locus-tag	class	description
AFL94_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
AFL94_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
AFL94_00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AFL94_00020	ENOG4105K7N	UPF0232 protein
AFL94_00025	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AFL94_00030	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AFL94_00035	ENOG4108ZED	Transmembrane domain of unknown function (DUF3566)
AFL94_00060	ENOG4105C09	Bile acid
AFL94_00075	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
AFL94_00090	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
AFL94_00095	ENOG4105KPY	Small multidrug resistance protein
AFL94_00100	ENOG4105ZJT	Cell division protein CrgA
AFL94_00105	ENOG4108U4N	(sortase) family
AFL94_00120	ENOG4105D9P	serine threonine protein kinase
AFL94_00125	ENOG4107TPY	serine threonine protein kinase
AFL94_00145	ENOG4105HZM	Fha domain containing protein
AFL94_00170	ENOG4105ETE	Transcriptional regulator (LacI family
AFL94_00175	ENOG4105DU0	nucleoside hydrolase
AFL94_00180	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
AFL94_00195	ENOG4105E39	Enoyl-CoA hydratase
AFL94_00205	ENOG4105D7K	pfkb domain protein
AFL94_00210	ENOG4108K4B	hydrolase
AFL94_00235	ENOG4105C2W	permease
AFL94_00240	ENOG4105DWF	phosphomethylpyrimidine kinase
AFL94_00245	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AFL94_00250	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
AFL94_00265	ENOG4105C26	Dehydrogenase
AFL94_00270	ENOG4108IQI	permease
AFL94_00275	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
AFL94_00290	ENOG4105VMP	Transcriptional regulator
AFL94_00295	ENOG4105DUX	Transporter
AFL94_00315	ENOG4107TE5	Lipid kinase
AFL94_00320	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AFL94_00325	ENOG4108X4Q	Hydrolase
AFL94_00355	ENOG4107QSV	RmuC domain protein
AFL94_00365	ENOG4105F0N	pyrophosphate phospho-hydrolase
AFL94_00370	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
AFL94_00380	ENOG4107RD1	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
AFL94_00390	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AFL94_00395	ENOG4105EUJ	GTP cyclohydrolase i
AFL94_00430	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
AFL94_00480	ENOG4108QIU	Dehydrogenase
AFL94_00485	ENOG4105C9K	Endothelin-converting enzyme 1
AFL94_00490	ENOG4105CRK	lysyL-tRNA synthetase
AFL94_00500	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AFL94_00540	ENOG4105CEN	a g-specific adenine glycosylase
AFL94_00550	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
AFL94_00555	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
AFL94_00565	ENOG4107QJG	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
AFL94_00580	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AFL94_00595	ENOG4105CJ3	phosphate transporter
AFL94_00645	ENOG4105C5H	ABC transporter
AFL94_00650	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AFL94_00670	ENOG4105C26	Dehydrogenase
AFL94_00685	ENOG4105CIR	epoxide hydrolase
AFL94_00695	ENOG4108TGP	Thioesterase superfamily protein
AFL94_00715	ENOG41080RH	Thioredoxin
AFL94_00730	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AFL94_00750	ENOG4105CQB	FAD linked oxidase domain protein
AFL94_00875	ENOG4105C7N	Xanthine uracil vitamin C permease
AFL94_00925	ENOG4105E39	Enoyl-CoA hydratase
AFL94_00940	ENOG4105C1G	acyl-Coa dehydrogenase
AFL94_00965	ENOG4107RMH	nh(3)-dependent nad( ) synthetase
AFL94_00975	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AFL94_00990	ENOG4105CJ1	ABC, transporter
AFL94_01005	ENOG4108JEZ	rRNA small subunit methyltransferase G
AFL94_01025	ENOG4108UGD	Serine Threonine protein kinase
AFL94_01080	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AFL94_01085	ENOG4105GR3	Histidine kinase
AFL94_01105	ENOG4105C85	amino acid
AFL94_01115	ENOG4107104	thymidine kinase
AFL94_01130	ENOG4105BZU	Histidine kinase
AFL94_01135	ENOG4108YZA	Nitrogen regulatory protein pii
AFL94_01160	ENOG4107RSM	transcriptional regulator
AFL94_01170	ENOG4108RNG	Permease of the drug metabolite transporter
AFL94_01185	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
AFL94_01195	ENOG4105C7K	acetolactate synthase
AFL94_01200	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AFL94_01220	ENOG4108ZJ4	polysaccharide deacetylase
AFL94_01235	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
AFL94_01240	ENOG4105DM4	PTS System
AFL94_01245	ENOG4105DE4	1-phosphofructokinase
AFL94_01250	ENOG4107EDW	L-fucose operon activator
AFL94_01260	ENOG4105TVJ	transport system, permease
AFL94_01265	ENOG4105DQ5	transport system permease protein
AFL94_01270	ENOG4108MES	Periplasmic binding protein
AFL94_01275	ENOG4105K4P	CoA-binding domain protein
AFL94_01285	ENOG4107TB6	phosphoglycerate mutase
AFL94_01290	ENOG4105K6V	RNA polymerase
AFL94_01295	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
AFL94_01300	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
AFL94_01310	ENOG4105C94	Transporter
AFL94_01315	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AFL94_01320	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
AFL94_01350	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AFL94_01370	ENOG4105ECR	NmrA family
AFL94_01380	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
AFL94_01385	ENOG4108UMI	ABC transporter, permease
AFL94_01390	ENOG4105D01	(LipO)protein
AFL94_01395	ENOG4105FDT	acyl-CoA dehydrogenase
AFL94_01405	ENOG4105K4P	CoA-binding domain protein
AFL94_01410	ENOG4105MSB	protein, conserved in bacteria
AFL94_01425	ENOG4105CGH	5'-nucleotidase
AFL94_01455	ENOG4105CPU	Monooxygenase
AFL94_01465	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
AFL94_01480	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
AFL94_01485	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
AFL94_01490	ENOG410839H	phosphoribosylformylglycinamidine synthase
AFL94_01495	ENOG4105K5B	UPF0225 protein
AFL94_01505	ENOG4107SFS	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity)
AFL94_01530	ENOG4105D4T	Citrate transporter
AFL94_01535	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
AFL94_01540	ENOG4108V9W	transcriptional regulatory protein
AFL94_01550	ENOG4105CFH	Aspartokinase
AFL94_01585	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
AFL94_01635	ENOG4105C85	amino acid
AFL94_01640	ENOG4107TB6	phosphoglycerate mutase
AFL94_01650	ENOG4107R9S	Malate synthase
AFL94_01660	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AFL94_01685	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AFL94_01690	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AFL94_01695	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
AFL94_01705	ENOG4105CUB	amino acid
AFL94_01720	ENOG4108FUF	Transcriptional regulator, IclR family
AFL94_01760	ENOG4105WH1	Two component transcriptional regulator luxr family
AFL94_01765	ENOG4105BZU	Histidine kinase
AFL94_01770	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
AFL94_01800	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
AFL94_01815	ENOG4105DWF	phosphomethylpyrimidine kinase
AFL94_01845	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
AFL94_01880	ENOG4108S0J	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates (By similarity)
AFL94_01885	ENOG4107QRT	dEAD DEAH box helicase
AFL94_01890	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
AFL94_01905	ENOG41088SP	formiminoglutamate hydrolase
AFL94_01910	ENOG4105D6U	Sodium Glutamate Symporter
AFL94_01915	ENOG4108JQ1	Dehydrogenase
AFL94_01930	ENOG4105DA5	(ABC) transporter
AFL94_01955	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
AFL94_01965	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
AFL94_01985	ENOG4108Q27	Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate (By similarity)
AFL94_01995	ENOG4105D2S	major facilitator superfamily
AFL94_02000	ENOG4105CHU	acetyl-coa acetyltransferase
AFL94_02010	ENOG4107QNJ	CoA-transferase subunit B
AFL94_02015	ENOG4107HP6	Transcriptional regulator
AFL94_02040	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
AFL94_02045	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AFL94_02050	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AFL94_02090	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AFL94_02115	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
AFL94_02140	ENOG4108IUE	nitrate reductase beta subunit
AFL94_02155	ENOG4105PTV	Nudix Hydrolase
AFL94_02180	ENOG4108Z6B	deaminase
AFL94_02185	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
AFL94_02190	ENOG4105BZU	Histidine kinase
AFL94_02195	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AFL94_02220	ENOG4108IG5	Transcriptional regulator
AFL94_02225	ENOG4105ECB	domain protein
AFL94_02255	ENOG4105CS2	ec 3.2.1.21
AFL94_02260	ENOG4105ETE	Transcriptional regulator (LacI family
AFL94_02280	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
AFL94_02285	ENOG4105C2C	drug resistance transporter, Bcr CflA
AFL94_02300	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
AFL94_02305	ENOG41081JD	Transcriptional regulator
AFL94_02320	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AFL94_02350	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
AFL94_02355	ENOG4105D22	carbon starvation protein
AFL94_02370	ENOG4105CV8	reductase
AFL94_02395	ENOG4107QMP	dna polymerase iii subunits gamma and tau
AFL94_02400	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
AFL94_02415	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AFL94_02430	ENOG4105BZU	Histidine kinase
AFL94_02445	ENOG4108VJ1	Transcriptional regulator (CarD family
AFL94_02450	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
AFL94_02455	ENOG4105C8N	cysteinyl-tRNA synthetase
AFL94_02460	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AFL94_02480	ENOG4105CQB	FAD linked oxidase domain protein
AFL94_02520	ENOG4108IJ9	(ABC) transporter
AFL94_02560	ENOG4107QMH	DNA methylase
AFL94_02570	ENOG4105CKW	Inner membrane protein yedI
AFL94_02605	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
AFL94_02620	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AFL94_02640	ENOG4105BZU	Histidine kinase
AFL94_02645	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AFL94_02655	ENOG4105VEQ	Cold shock protein
AFL94_02665	ENOG4107R8H	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
AFL94_02670	ENOG4107R5H	iron (metal) dependent repressor, dtxr family
AFL94_02675	ENOG4105DR5	peptidase
AFL94_02715	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
AFL94_02785	ENOG4105C7K	acetolactate synthase
AFL94_02795	ENOG4105ECY	inositol monophosphatase
AFL94_02820	ENOG4105G9B	Transcriptional regulator
AFL94_02825	ENOG4105C1G	acyl-Coa dehydrogenase
AFL94_02830	ENOG4105C26	Dehydrogenase
AFL94_02835	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AFL94_02860	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AFL94_02875	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AFL94_02880	ENOG4107R34	abc transporter permease protein
AFL94_02925	ENOG4107U9T	Pfam:Ribonuclease_BN
AFL94_02930	ENOG4106839	domain protein
AFL94_02935	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
AFL94_02945	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
AFL94_03010	ENOG41079KZ	Major Facilitator Superfamily
AFL94_03020	ENOG4105DC1	bifunctional purine biosynthesis protein purh
AFL94_03025	ENOG4105C94	Transporter
AFL94_03045	ENOG4105C5A	transporter
AFL94_03050	ENOG4105CFM	UPF0317 protein
AFL94_03080	ENOG4108JIK	carboxylase
AFL94_03085	ENOG4107R7A	Allophanate hydrolase subunit 2
AFL94_03090	ENOG4105E7W	lamb ycsf family protein
AFL94_03110	ENOG4105E9K	Isocitrate dehydrogenase
AFL94_03120	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
AFL94_03125	ENOG4108WYP	Transcriptional regulator
AFL94_03135	ENOG4108R85	Short chain dehydrogenase
AFL94_03170	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AFL94_03190	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
AFL94_03245	ENOG41086D8	Transcriptional regulator
AFL94_03250	ENOG4108Z0R	Transferase
AFL94_03265	ENOG4105F95	Monooxygenase
AFL94_03270	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AFL94_03300	ENOG4105Y3U	Transglycosylase-associated protein
AFL94_03305	ENOG4105CSH	Transporter
AFL94_03310	ENOG4105DUM	transcriptional regulator, lysR family
AFL94_03320	ENOG4105WH1	Two component transcriptional regulator luxr family
AFL94_03345	ENOG4105CGK	Exodeoxyribonuclease III
AFL94_03350	ENOG4105C31	Tryptophanyl-tRNA synthetase
AFL94_03370	ENOG4105CHH	sulfate transporter
AFL94_03380	ENOG4105E6M	Sulphatase-modifying factor protein
AFL94_03385	ENOG4105WH1	Two component transcriptional regulator luxr family
AFL94_03410	ENOG4105E33	succinate dehydrogenase
AFL94_03430	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
AFL94_03435	ENOG4105C94	Transporter
AFL94_03440	ENOG4107RM1	amidohydrolase
AFL94_03445	ENOG4105DIH	basic membrane
AFL94_03450	ENOG4108JQ9	ABC transporter
AFL94_03455	ENOG4105UIB	(ABC) transporter
AFL94_03480	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
AFL94_03495	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AFL94_03515	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AFL94_03545	ENOG4105C7B	Threonine dehydratase
AFL94_03550	ENOG4107YD5	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
AFL94_03560	ENOG4105T1M	mycothiol conjugate amidase mca
AFL94_03575	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AFL94_03580	ENOG4108IAB	Phoh family
AFL94_03600	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AFL94_03625	ENOG4105C9Q	fumarate hydratase class II
AFL94_03645	ENOG4105EIP	mannose-6-phosphate isomerase
AFL94_03650	ENOG4108KGH	TRANSCRIPTIONal
AFL94_03655	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
AFL94_03675	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
AFL94_03715	ENOG4105FF9	glycosyl transferase, family 39
AFL94_03740	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AFL94_03745	ENOG4105F8V	Hydrolase, tatD family
AFL94_03750	ENOG4106839	domain protein
AFL94_03755	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AFL94_03760	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
AFL94_03775	ENOG4105C87	Aminotransferase class I and II
AFL94_03790	ENOG4105C5H	ABC transporter
AFL94_03800	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AFL94_03820	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
AFL94_03835	ENOG4108UNV	SUF system FeS assembly protein, NifU family
AFL94_03840	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AFL94_03870	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
AFL94_03875	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
AFL94_03890	ENOG4105CSH	Transporter
AFL94_03910	ENOG4108JIK	carboxylase
AFL94_03920	ENOG4106032	Glutathionylspermidine synthase
AFL94_03930	ENOG4107WR6	Maf-like protein
AFL94_03935	ENOG4105EYF	MMPL domain protein
AFL94_03950	ENOG4108ETY	sodium dicarboxylate symporter
AFL94_03955	ENOG4105NPE	arsR family transcriptional regulator
AFL94_03960	ENOG41090KQ	Glyoxalase Bleomycin resistance protein (Dioxygenase
AFL94_03970	ENOG4105C2C	drug resistance transporter, Bcr CflA
AFL94_03985	ENOG4105D8K	carboxyl transferase
AFL94_04015	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
AFL94_04040	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
AFL94_04045	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
AFL94_04075	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AFL94_04080	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AFL94_04085	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AFL94_04105	ENOG4105DEF	Extracellular solute-binding protein, family 5
AFL94_04110	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AFL94_04125	ENOG4108JQ7	(ABC) transporter
AFL94_04135	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
AFL94_04145	ENOG4105EV4	Multidrug resistance protein mdtH
AFL94_04155	ENOG4105CPQ	Dehydrogenase
AFL94_04160	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AFL94_04165	ENOG4105ETE	Transcriptional regulator (LacI family
AFL94_04170	ENOG4105EPJ	extracellular solute-binding protein family 1
AFL94_04175	ENOG4105S9S	Binding-protein-dependent transport systems, inner membrane component
AFL94_04180	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
AFL94_04195	ENOG4105CGP	Urocanate hydratase
AFL94_04200	ENOG4105DWD	nucleoside recognition domain protein
AFL94_04210	ENOG4105CI2	imidazolone-5-propionate hydrolase
AFL94_04215	ENOG4105CI2	imidazolone-5-propionate hydrolase
AFL94_04220	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
AFL94_04225	ENOG4105C2X	Arabinose 5-phosphate isomerase
AFL94_04230	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
AFL94_04235	ENOG4105DE4	1-phosphofructokinase
AFL94_04265	ENOG4105E98	transcriptional regulator DeoR family
AFL94_04295	ENOG4108IQK	o-acetylhomoserine
AFL94_04300	ENOG4105DWV	Homoserine O-trans-acetylase
AFL94_04305	ENOG41090WU	lipolytic protein G-D-S-L family
AFL94_04320	ENOG4105WQ3	Rna-binding protein
AFL94_04325	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
AFL94_04365	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
AFL94_04370	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AFL94_04415	ENOG4105DUU	IucA IucC family protein
AFL94_04420	ENOG4105F1Y	L-lysine 6-monooxygenase (NADPH)
AFL94_04435	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AFL94_04455	ENOG4107TYR	Glycosyl Transferase
AFL94_04470	ENOG4105CE9	30S ribosomal protein S2
AFL94_04475	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
AFL94_04480	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AFL94_04485	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
AFL94_04490	ENOG4105KNE	Phosphatidate cytidylyltransferase
AFL94_04510	ENOG4105DY9	regulatoR
AFL94_04515	ENOG4108HRK	Histidine kinase
AFL94_04525	ENOG4107QN1	sodium solute
AFL94_04530	ENOG4107W19	lmbE family
AFL94_04535	ENOG4105CPF	Cell wall formation (By similarity)
AFL94_04540	ENOG4105CND	Glycosyl transferase, family 2
AFL94_04555	ENOG4105CPP	Dehydrogenase, E1 component
AFL94_04560	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
AFL94_04565	ENOG4105DEF	Extracellular solute-binding protein, family 5
AFL94_04570	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AFL94_04575	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AFL94_04595	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AFL94_04615	ENOG4105C1G	acyl-Coa dehydrogenase
AFL94_04620	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
AFL94_04625	ENOG4105DZP	Membrane-associated zinc metalloprotease
AFL94_04645	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
AFL94_04675	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AFL94_04685	ENOG4105WH1	Two component transcriptional regulator luxr family
AFL94_04690	ENOG4105BZU	Histidine kinase
AFL94_04700	ENOG4107S2Z	UPF0761 membrane protein
AFL94_04715	ENOG4107Z1I	Required for maturation of 30S ribosomal subunits (By similarity)
AFL94_04725	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AFL94_04730	ENOG4107ZPY	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
AFL94_04760	ENOG4105CK7	Sodium proline symporter
AFL94_04765	ENOG4105CSH	Transporter
AFL94_04770	ENOG4105CWC	Acetylornithine deacetylase
AFL94_04785	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
AFL94_04800	ENOG4105DTN	riboflavin biosynthesis protein ribF
AFL94_04810	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
AFL94_04860	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
AFL94_04865	ENOG410680H	amp-dependent synthetase and ligase
AFL94_04870	ENOG4105E2T	synthase III
AFL94_04880	ENOG4105SHT	UspA domain-containing protein
AFL94_04905	ENOG4108MRH	transcriptional regulatory protein
AFL94_04915	ENOG4105DJ2	Major Facilitator Superfamily
AFL94_04920	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AFL94_04925	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AFL94_05025	ENOG4105KME	endoribonuclease L-psp
AFL94_05035	ENOG41080X4	futalosine nucleosidase
AFL94_05040	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
AFL94_05055	ENOG4107S1Q	Phosphatase
AFL94_05060	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
AFL94_05065	ENOG4107RSM	transcriptional regulator
AFL94_05070	ENOG4105CSH	Transporter
AFL94_05075	ENOG4107S9B	Shikimate dehydrogenase
AFL94_05090	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
AFL94_05100	ENOG4105CPQ	Dehydrogenase
AFL94_05105	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
AFL94_05120	ENOG4105C1V	Peptidase, M16
AFL94_05135	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
AFL94_05150	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AFL94_05155	ENOG4105CN5	Metallo-Beta-Lactamase
AFL94_05170	ENOG4105YB8	TM2 domain containing protein
AFL94_05180	ENOG4105E90	ABC transporter
AFL94_05195	ENOG4107QZI	cell division protein FtsK
AFL94_05205	ENOG4105CEV	competence damage-inducible protein
AFL94_05220	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AFL94_05230	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AFL94_05235	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
AFL94_05240	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
AFL94_05245	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
AFL94_05250	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
AFL94_05260	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
AFL94_05270	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AFL94_05275	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
AFL94_05280	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
AFL94_05285	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
AFL94_05305	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
AFL94_05315	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
AFL94_05320	ENOG4108RWN	rrna methyltransferase
AFL94_05325	ENOG4105M6F	mutator MutT protein
AFL94_05335	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AFL94_05340	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
AFL94_05345	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
AFL94_05360	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
AFL94_05390	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
AFL94_05395	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
AFL94_05400	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
AFL94_05405	ENOG4105CAS	nag kinase
AFL94_05410	ENOG4105C8Y	Acetylornithine aminotransferase
AFL94_05415	ENOG4105DBV	ornithine carbamoyltransferase
AFL94_05420	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
AFL94_05425	ENOG4108UVJ	appr-1-p processing domain protein
AFL94_05430	ENOG4105CH7	arginosuccinase
AFL94_05440	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
AFL94_05450	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AFL94_05480	ENOG4105DSU	hydrolase
AFL94_05495	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
AFL94_05500	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
AFL94_05505	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
AFL94_05510	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
AFL94_05515	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AFL94_05525	ENOG4105VMP	Transcriptional regulator
AFL94_05540	ENOG4105CR4	methylisocitrate lyase
AFL94_05555	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AFL94_05565	ENOG4108MRH	transcriptional regulatory protein
AFL94_05570	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
AFL94_05575	ENOG4107QJT	sodium dicarboxylate symporter
AFL94_05590	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
AFL94_05595	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
AFL94_05610	ENOG4105CAT	Cytidine monophosphate kinase
AFL94_05615	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AFL94_05625	ENOG4105JAB	phenazine biosynthesis protein, phzf family
AFL94_05640	ENOG4105QPS	Monooxygenase
AFL94_05645	ENOG4105K78	MarR family Transcriptional regulator
AFL94_05650	ENOG4108UW8	fha domain-containing protein
AFL94_05670	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
AFL94_05675	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
AFL94_05685	ENOG4108IQE	Amp-dependent synthetase and ligase
AFL94_05705	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
AFL94_05725	ENOG4105EC2	ftsk spoIIIe
AFL94_05765	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
AFL94_05770	ENOG4105CAK	Cell division ATP-binding protein ftsE
AFL94_05775	ENOG4107RYD	Part of the ABC transporter FtsEX involved in cellular division (By similarity)
AFL94_05780	ENOG4105E4C	Lytic transglycosylase catalytic
AFL94_05785	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
AFL94_05795	ENOG41083TI	Protein CrcB homolog
AFL94_05800	ENOG4107JBM	CrcB-like protein
AFL94_05805	ENOG4108U51	Universal stress protein
AFL94_05810	ENOG4107RPQ	ABC transporter
AFL94_05815	ENOG4107TK4	histidinol-phosphate phosphatase
AFL94_05825	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
AFL94_05830	ENOG4105EMN	RNA polymerase sigma factor
AFL94_05845	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
AFL94_05850	ENOG4105C37	(CBS) domain
AFL94_05855	ENOG4105C37	(CBS) domain
AFL94_05860	ENOG4105DIK	(ABC) transporter
AFL94_05885	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
AFL94_05895	ENOG4107ZUX	Histidine triad (HIT) protein
AFL94_05900	ENOG4105CQ7	ATP-dependent helicase
AFL94_05925	ENOG4105C75	arginyL-tRNA synthetase
AFL94_05930	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
AFL94_05935	ENOG4105D6E	homoserine dehydrogenase
AFL94_05940	ENOG4107R5I	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
AFL94_05945	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
AFL94_05955	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
AFL94_05960	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AFL94_05965	ENOG4107UIY	sua5 ycio yrdc ywlc family protein
AFL94_05970	ENOG4105ESV	Glycosyl transferase, family 4
AFL94_05980	ENOG4107UH5	it plays a direct role in the translocation of protons across the membrane (By similarity)
AFL94_05985	ENOG4106DE0	ATP synthase
AFL94_05990	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
AFL94_05995	ENOG4108T62	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AFL94_06000	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
AFL94_06005	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
AFL94_06010	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
AFL94_06015	ENOG410825K	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AFL94_06030	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
AFL94_06080	ENOG4105CRK	lysyL-tRNA synthetase
AFL94_06095	ENOG4108RWI	nicotinamidase
AFL94_06100	ENOG4107RKP	Nicotinate phosphoribosyltransferase
AFL94_06105	ENOG4105KEN	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
AFL94_06115	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
AFL94_06120	ENOG4108RQ5	Beta-lactamase domain-containing protein
AFL94_06135	ENOG4105EUJ	GTP cyclohydrolase i
AFL94_06150	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
AFL94_06155	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AFL94_06165	ENOG4105DVE	abc transporter atp-binding protein
AFL94_06175	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
AFL94_06190	ENOG4107RH8	nuclease SbcCD subunit D
AFL94_06195	ENOG4105EYH	Exonuclease
AFL94_06215	ENOG4105ETE	Transcriptional regulator (LacI family
AFL94_06220	ENOG4105CG3	alpha amylase, catalytic region
AFL94_06230	ENOG4105D56	permease protein
AFL94_06235	ENOG4105EG2	ABC transporter, permease
AFL94_06275	ENOG4105CRK	lysyL-tRNA synthetase
AFL94_06290	ENOG4108RWI	nicotinamidase
AFL94_06295	ENOG4107RKP	Nicotinate phosphoribosyltransferase
AFL94_06300	ENOG4105KEN	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
AFL94_06310	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
AFL94_06315	ENOG4108RQ5	Beta-lactamase domain-containing protein
AFL94_06330	ENOG4105EUJ	GTP cyclohydrolase i
AFL94_06345	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
AFL94_06350	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AFL94_06360	ENOG4105DVE	abc transporter atp-binding protein
AFL94_06370	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
AFL94_06385	ENOG4107RH8	nuclease SbcCD subunit D
AFL94_06390	ENOG4105EYH	Exonuclease
AFL94_06410	ENOG4105ETE	Transcriptional regulator (LacI family
AFL94_06415	ENOG4105CG3	alpha amylase, catalytic region
AFL94_06425	ENOG4105D56	permease protein
AFL94_06430	ENOG4105EG2	ABC transporter, permease
AFL94_06485	ENOG4105C26	Dehydrogenase
AFL94_06490	ENOG4108WYP	Transcriptional regulator
AFL94_06510	ENOG4105C01	Dihydroxy-acid dehydratase
AFL94_06535	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
AFL94_06545	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
AFL94_06585	ENOG4105K56	Transcriptional regulator
AFL94_06595	ENOG4105W5T	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
AFL94_06600	ENOG4105DTJ	flagellar hook-associated protein
AFL94_06605	ENOG4105E1Q	flagellar hook-associated protein
AFL94_06615	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AFL94_06620	ENOG4105I03	Flagellin
AFL94_06625	ENOG410804A	Flagellar hook-associated 2 domain-containing protein
AFL94_06640	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
AFL94_06645	ENOG4108ZC9	flagellar basal-body rod protein flgc
AFL94_06655	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
AFL94_06680	ENOG4107SN7	NLP P60 protein
AFL94_06695	ENOG4105BZE	flagellar hook protein, FlgE
AFL94_06705	ENOG4105E14	MotA TolQ exbB proton channel
AFL94_06710	ENOG4106VK6	Flagellar motor protein
AFL94_06720	ENOG4105DD5	Flagellar motor switch protein
AFL94_06730	ENOG4105CN7	Flagellar biosynthetic protein FliP
AFL94_06735	ENOG4105VS8	Flagellar biosynthetic protein fliq
AFL94_06745	ENOG4105D00	flagellar biosynthetic protein flhB
AFL94_06750	ENOG4105D7B	Flagellar biosynthesis protein flha
AFL94_06760	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
AFL94_06795	ENOG4105DWT	malate dehydrogenase (quinone)
AFL94_06805	ENOG4105F9U	Dehydrogenase
AFL94_06845	ENOG4105CGD	Nad-dependent epimerase dehydratase
AFL94_06890	ENOG4108ZEY	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
AFL94_06900	ENOG4105BZU	Histidine kinase
AFL94_06915	ENOG410802X	bacteriophage n4 adsorption protein b
AFL94_06925	ENOG4105C01	Dihydroxy-acid dehydratase
AFL94_06930	ENOG4105C7K	acetolactate synthase
AFL94_06935	ENOG4108ZP8	Acetolactate synthase small subunit
AFL94_06940	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
AFL94_06955	ENOG4107QPT	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
AFL94_06960	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
AFL94_06975	ENOG41086KC	Transcriptional regulator
AFL94_06990	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
AFL94_06995	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
AFL94_07055	ENOG4105J5G	Transferase hexapeptide repeat containing protein
AFL94_07115	ENOG4105JEU	Glycosyl transferase, family 2
AFL94_07200	ENOG4105WH1	Two component transcriptional regulator luxr family
AFL94_07205	ENOG4105BZU	Histidine kinase
AFL94_07210	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AFL94_07215	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AFL94_07220	ENOG4105CMR	udp-glucose 4-epimerase
AFL94_07225	ENOG4105ERH	Fumarylacetoacetate hydrolase
AFL94_07230	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AFL94_07235	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AFL94_07255	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
AFL94_07265	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
AFL94_07275	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AFL94_07280	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AFL94_07285	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AFL94_07295	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AFL94_07300	ENOG4105CPF	Cell wall formation (By similarity)
AFL94_07310	ENOG4108KGH	TRANSCRIPTIONal
AFL94_07315	ENOG4105DP4	dak2 domain fusion protein ylov
AFL94_07325	ENOG4106H78	methyltransferase
AFL94_07340	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
AFL94_07345	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
AFL94_07350	ENOG4108KGH	TRANSCRIPTIONal
AFL94_07360	ENOG4105EY8	ABC transporter
AFL94_07375	ENOG4107YSK	Glycerol-3-phosphate cytidylyltransferase
AFL94_07385	ENOG4107VDP	teichoic acid biosynthesis
AFL94_07405	ENOG4108I69	Glycosyl transferases group 1
AFL94_07425	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
AFL94_07435	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
AFL94_07445	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AFL94_07450	ENOG4105EXC	Acyl-transferase
AFL94_07480	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AFL94_07485	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AFL94_07490	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
AFL94_07525	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AFL94_07530	ENOG4105CHU	acetyl-coa acetyltransferase
AFL94_07535	ENOG4105DBE	peroxidase
AFL94_07540	ENOG410650H	(LipO)protein
AFL94_07575	ENOG41090CE	integral membrane protein
AFL94_07585	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
AFL94_07615	ENOG4105C1G	acyl-Coa dehydrogenase
AFL94_07620	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AFL94_07665	ENOG4107XFJ	UPF0246 protein
AFL94_07670	ENOG4105HRU	Glyoxalase Bleomycin resistance protein (Dioxygenase
AFL94_07675	ENOG4105EGD	dinuclear metal center protein, YbgI family
AFL94_07680	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
AFL94_07685	ENOG4105C6T	cysteine synthase
AFL94_07690	ENOG4105D7W	serine acetyltransferase
AFL94_07700	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AFL94_07715	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AFL94_07720	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
AFL94_07740	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
AFL94_07750	ENOG4105C6Z	Gluconate
AFL94_07755	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
AFL94_07760	ENOG4105Y3U	Transglycosylase-associated protein
AFL94_07770	ENOG4108UT2	hemolysin iii
AFL94_07775	ENOG41067RQ	csbd family
AFL94_07810	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
AFL94_07825	ENOG41082KT	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AFL94_07830	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AFL94_07850	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AFL94_07860	ENOG4105C0P	Mg chelatase subunit ChlI
AFL94_07865	ENOG41080R2	UPF0102 protein
AFL94_07875	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AFL94_07880	ENOG4107QYR	Signal peptidase i
AFL94_07890	ENOG4107QYR	Signal peptidase i
AFL94_07895	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
AFL94_07900	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
AFL94_07905	ENOG4107XUM	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
AFL94_07910	ENOG41082KU	UPF0109 protein
AFL94_07915	ENOG4105K5M	30s ribosomal protein S16
AFL94_07920	ENOG4105N14	lysine exporter protein LysE YggA
AFL94_07960	ENOG4105C5H	ABC transporter
AFL94_07985	ENOG4105CHR	reductase
AFL94_07990	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
AFL94_08020	ENOG4105DKW	ABC transporter
AFL94_08030	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AFL94_08035	ENOG4105NRA	50s ribosomal protein l31 type b
AFL94_08040	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
AFL94_08045	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
AFL94_08110	ENOG4105CHR	reductase
AFL94_08120	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AFL94_08135	ENOG4107EFR	Flavocytochrome c
AFL94_08145	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
AFL94_08150	ENOG4108KXV	response regulator
AFL94_08155	ENOG41062D9	Histidine kinase
AFL94_08165	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AFL94_08185	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AFL94_08190	ENOG4105C8N	cysteinyl-tRNA synthetase
AFL94_08200	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
AFL94_08215	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
AFL94_08220	ENOG4105E5F	proteasome
AFL94_08230	ENOG4105DVV	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine (By similarity)
AFL94_08235	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AFL94_08260	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
AFL94_08275	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
AFL94_08300	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AFL94_08320	ENOG4105NAE	bifunctional deaminase-reductase domain protein
AFL94_08350	ENOG4108I0Q	anthranilate phosphoribosyltransferase
AFL94_08355	ENOG4105CCU	oxidase (Subunit III)
AFL94_08360	ENOG4107UDY	cytochrome C
AFL94_08365	ENOG4107EUI	c reductase, iron-sulfur
AFL94_08370	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AFL94_08380	ENOG4105FDP	GntR family transcriptional regulator
AFL94_08385	ENOG4108ZRS	Part of cytochrome c oxidase, its function is
AFL94_08390	ENOG4105BZ9	Cytochrome C oxidase, subunit I
AFL94_08395	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
AFL94_08415	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
AFL94_08420	ENOG4105E5G	Alpha beta hydrolase fold
AFL94_08425	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AFL94_08430	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
AFL94_08435	ENOG4107QXN	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AFL94_08445	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
AFL94_08455	ENOG4107VNR	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
AFL94_08470	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
AFL94_08475	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AFL94_08480	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
AFL94_08500	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
AFL94_08510	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
AFL94_08520	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
AFL94_08530	ENOG4105EPR	degv family
AFL94_08535	ENOG4105C8T	Leucyl-tRNA synthetase
AFL94_08550	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
AFL94_08555	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
AFL94_08565	ENOG4105DKT	Transcriptional regulator
AFL94_08585	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
AFL94_08595	ENOG4105MTQ	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
AFL94_08600	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AFL94_08610	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
AFL94_08615	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AFL94_08620	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AFL94_08630	ENOG4105CD3	dihydroorotase
AFL94_08635	ENOG4105CXT	aspartate transcarbamylase
AFL94_08640	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
AFL94_08645	ENOG410803B	Involved in the transcription termination process (By similarity)
AFL94_08650	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AFL94_08660	ENOG4105D49	3-dehydroquinate synthase
AFL94_08665	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
AFL94_08670	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
AFL94_08675	ENOG4105E2X	shikimate dehydrogenase
AFL94_08685	ENOG41080G3	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
AFL94_08690	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AFL94_08985	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AFL94_08990	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AFL94_09000	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
AFL94_09015	ENOG4105C9M	aspartyl-trna synthetase
AFL94_09020	ENOG4105CUT	histidyl-tRNA synthetase
AFL94_09025	ENOG4105C99	atpase involved in dna repair
AFL94_09035	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AFL94_09040	ENOG4107RTU	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AFL94_09050	ENOG4105VIE	preprotein translocase, subunit YajC
AFL94_09055	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
AFL94_09060	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
AFL94_09065	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
AFL94_09070	ENOG4105CDY	transcriptional regulatory protein
AFL94_09075	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
AFL94_09085	ENOG4105DGW	oligopeptidase A
AFL94_09090	ENOG4108U7W	acetyltransferase
AFL94_09105	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
AFL94_09110	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
AFL94_09115	ENOG4105BZ7	extracellular solute-binding protein family 1
AFL94_09120	ENOG4105DRS	transport system, permease
AFL94_09130	ENOG4105N2W	Transcriptional regulator
AFL94_09135	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
AFL94_09145	ENOG4105CIG	ABC transporter
AFL94_09160	ENOG4107WHG	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
AFL94_09170	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AFL94_09175	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
AFL94_09180	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
AFL94_09190	ENOG4105C22	threonyL-tRNA synthetase
AFL94_09220	ENOG4105RHY	Pfam:UPF0157
AFL94_09225	ENOG4105C0B	DNA polymerase III (alpha subunit)
AFL94_09240	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
AFL94_09245	ENOG4105CSH	Transporter
AFL94_09250	ENOG4105CV8	reductase
AFL94_09260	ENOG4105C5X	domain protein
AFL94_09270	ENOG4108RAV	Conserved protein
AFL94_09310	ENOG4108HH4	Major Facilitator Superfamily
AFL94_09325	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AFL94_09330	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AFL94_09335	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
AFL94_09345	ENOG4105DFA	alanine racemase domain protein
AFL94_09350	ENOG4105C7K	acetolactate synthase
AFL94_09355	ENOG4105DFA	alanine racemase domain protein
AFL94_09380	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AFL94_09410	ENOG4105C5H	ABC transporter
AFL94_09415	ENOG4105IW1	AmiS UreI transporter
AFL94_09420	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
AFL94_09425	ENOG4105DND	Transcriptional regulator
AFL94_09440	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
AFL94_09450	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AFL94_09455	ENOG4105C85	amino acid
AFL94_09475	ENOG4105D7N	magnesium and cobalt transport protein CorA
AFL94_09520	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
AFL94_09530	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
AFL94_09540	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
AFL94_09545	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
AFL94_09550	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AFL94_09555	ENOG4105K46	50S ribosomal protein l27
AFL94_09560	ENOG410826X	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
AFL94_09565	ENOG4105C03	ribonuclease
AFL94_09600	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
AFL94_09610	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
AFL94_09615	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AFL94_09630	ENOG4105ENE	Histidine kinase
AFL94_09635	ENOG4105WH1	Two component transcriptional regulator luxr family
AFL94_09640	ENOG4105EYF	MMPL domain protein
AFL94_09650	ENOG4105K56	Transcriptional regulator
AFL94_09655	ENOG4108ZHJ	Organic hydroperoxide resistance protein
AFL94_09715	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
AFL94_09740	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
AFL94_09750	ENOG4105MC2	DSBA oxidoreductase
AFL94_09755	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
AFL94_09760	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AFL94_09765	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AFL94_09770	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
AFL94_09795	ENOG4108YZG	isomerase
AFL94_09820	ENOG4105C29	acyl-CoA thioesterase
AFL94_09825	ENOG4108Z4X	TRANSCRIPTIONal
AFL94_09865	ENOG4108XM1	transcriptional regulator AsnC family
AFL94_09870	ENOG4105N14	lysine exporter protein LysE YggA
AFL94_09875	ENOG4108JJB	ABC transporter
AFL94_09880	ENOG4107QCX	Transporter
AFL94_09885	ENOG4107ZYJ	bioY protein
AFL94_09890	ENOG4105CEY	Amp-dependent synthetase and ligase
AFL94_09895	ENOG4105CHU	acetyl-coa acetyltransferase
AFL94_09900	ENOG4105VG1	fes assembly suf system protein
AFL94_09905	ENOG4105VG1	fes assembly suf system protein
AFL94_09910	ENOG4105C3K	feS assembly ATPase SufC
AFL94_09930	ENOG4105CJ1	ABC, transporter
AFL94_09955	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
AFL94_09965	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
AFL94_09985	ENOG4107XU2	6-phosphogluconolactonase (EC 3.1.1.31)
AFL94_10010	ENOG4105CP7	Triose-phosphate isomerase
AFL94_10015	ENOG4105BZA	Phosphoglycerate kinase
AFL94_10030	ENOG4105CIE	May be required for sporulation (By similarity)
AFL94_10035	ENOG4105CHW	UPF0052 protein
AFL94_10040	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
AFL94_10045	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
AFL94_10055	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AFL94_10060	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AFL94_10090	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
AFL94_10150	ENOG4108V8F	Transcriptional regulator, MarR family
AFL94_10160	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
AFL94_10185	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
AFL94_10195	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
AFL94_10220	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AFL94_10240	ENOG4108TZA	Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules (By similarity)
AFL94_10270	ENOG4105CA9	Pyruvate kinase
AFL94_10280	ENOG4105CBC	glutamate synthase
AFL94_10285	ENOG4107SYZ	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
AFL94_10290	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
AFL94_10295	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AFL94_10300	ENOG4105DK0	Indole-3-glycerol phosphate synthase
AFL94_10320	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
AFL94_10330	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
AFL94_10335	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
AFL94_10340	ENOG4105M0N	phosphoribosyl-ATP pyrophosphatase
AFL94_10345	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
AFL94_10350	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AFL94_10370	ENOG4105DJV	ribulose-phosphate 3-epimerase
AFL94_10380	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
AFL94_10385	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AFL94_10440	ENOG4105DKK	Benzoate
AFL94_10445	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
AFL94_10460	ENOG4108Z66	YbaK ebsC protein
AFL94_10470	ENOG4105E0X	reductase
AFL94_10500	ENOG4105CHU	acetyl-coa acetyltransferase
AFL94_10505	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AFL94_10520	ENOG4105CPC	Aldo Keto reductase
AFL94_10525	ENOG4105CDH	Citrulline--aspartate ligase
AFL94_10550	ENOG4105EVI	UPF0374 protein
AFL94_10555	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
AFL94_10600	ENOG4107QM5	aconitate hydratase
AFL94_10605	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AFL94_10610	ENOG4105C0X	amino acid
AFL94_10615	ENOG4107VEG	TrkA-N domain protein
AFL94_10640	ENOG4107ZFB	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
AFL94_10670	ENOG410870F	Cyclic nucleotide-binding protein
AFL94_10675	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AFL94_10680	ENOG4108JJ9	ABC, transporter
AFL94_10685	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AFL94_10690	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AFL94_10705	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AFL94_10715	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AFL94_10735	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AFL94_10755	ENOG4105D9P	serine threonine protein kinase
AFL94_10760	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
AFL94_10765	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
AFL94_10780	ENOG4105C5F	glutamine synthetase
AFL94_10790	ENOG4107Y2X	deaminase
AFL94_10800	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
AFL94_10805	ENOG4105C5F	glutamine synthetase
AFL94_10810	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
AFL94_10825	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
AFL94_10830	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
AFL94_10835	ENOG4105C0B	DNA polymerase III (alpha subunit)
AFL94_10845	ENOG4107ZIW	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
AFL94_10860	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
AFL94_10865	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
AFL94_10870	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AFL94_10875	ENOG4108UFP	Essential cell division protein (By similarity)
AFL94_10880	ENOG4105DFU	Cell wall formation (By similarity)
AFL94_10885	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
AFL94_10890	ENOG4105CNI	cell division protein FtsW
AFL94_10895	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
AFL94_10900	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
AFL94_10915	ENOG4105CJN	penicillin-binding protein
AFL94_10925	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
AFL94_10930	ENOG4108V6E	Cell division protein mraZ
AFL94_10940	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AFL94_10965	ENOG4105C7I	Dehydrogenase
AFL94_10995	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AFL94_11000	ENOG4105T0Z	Conserved Protein
AFL94_11005	ENOG4108S7Q	sigma 54 modulation protein ribosomal protein S30ea
AFL94_11010	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
AFL94_11015	ENOG4108T3R	lipoprotein lpqB
AFL94_11020	ENOG4105BZU	Histidine kinase
AFL94_11025	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AFL94_11040	ENOG4108JQ6	ABC transporter
AFL94_11045	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AFL94_11050	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AFL94_11055	ENOG4105KNR	Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity)
AFL94_11070	ENOG4105CB5	ATP-dependent DNA helicase recG
AFL94_11075	ENOG4108M8W	Monooxygenase
AFL94_11085	ENOG4105CEI	nitrite reductase
AFL94_11105	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
AFL94_11120	ENOG4105EEI	dihydropteroate synthase
AFL94_11135	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AFL94_11140	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
AFL94_11155	ENOG4105C10	Electron transfer flavoprotein
AFL94_11165	ENOG4105C0H	protease
AFL94_11175	ENOG41087YS	Phage shock protein A
AFL94_11195	ENOG4105DJZ	UPF0182 protein
AFL94_11200	ENOG41063PX	domain protein
AFL94_11250	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
AFL94_11255	ENOG4108UMI	ABC transporter, permease
AFL94_11260	ENOG4105D01	(LipO)protein
AFL94_11265	ENOG4105CUB	amino acid
AFL94_11270	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AFL94_11275	ENOG4105D52	delta-aminolevulinic acid dehydratase
AFL94_11290	ENOG4107QME	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
AFL94_11295	ENOG4107JTW	chlorite dismutase
AFL94_11300	ENOG4105C1Q	protoporphyrinogen oxidase
AFL94_11305	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
AFL94_11310	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
AFL94_11315	ENOG4108R86	Transcriptional regulator
AFL94_11335	ENOG4105CEC	DNA methylase N-4 N-6
AFL94_11345	ENOG4107T6F	Xaa-Pro aminopeptidase
AFL94_11355	ENOG4105CJW	magnesium transporter
AFL94_11365	ENOG4105D1F	ATP-binding protein
AFL94_11370	ENOG4105UTW	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
AFL94_11375	ENOG4105DU6	RNA polymerase
AFL94_11380	ENOG4107ZBN	O-methyltransferase
AFL94_11390	ENOG4108URH	decarboxylase
AFL94_11395	ENOG4105CDA	abc transporter atp-binding protein
AFL94_11400	ENOG4107UBR	Extracellular solute-binding protein family 3
AFL94_11405	ENOG4108Q1T	ABC transporter
AFL94_11410	ENOG4105DRP	amino acid AbC transporter
AFL94_11415	ENOG4107R4C	succinyl-diaminopimelate desuccinylase
AFL94_11420	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
AFL94_11440	ENOG4108Z4U	Ferredoxin
AFL94_11465	ENOG4105CI3	gtp-binding protein typa
AFL94_11480	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
AFL94_11510	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
AFL94_11620	ENOG4108X6U	May play a role in the intracellular transport of hydrophobic ligands
AFL94_11630	ENOG4105EI2	Pseudouridine synthase
AFL94_11645	ENOG4105CKK	Glycosyl transferase, family 2
AFL94_11680	ENOG4105C3G	gtp-binding protein
AFL94_11685	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
AFL94_11690	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AFL94_11695	ENOG4105YX8	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AFL94_11705	ENOG4105CSR	polyphosphate kinase 2
AFL94_11740	ENOG4108Z9I	-acetyltransferase
AFL94_11745	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
AFL94_11765	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AFL94_11780	ENOG4107QVP	Dehydrogenase
AFL94_11805	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AFL94_11810	ENOG4105EXC	Acyl-transferase
AFL94_11825	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AFL94_11830	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AFL94_11835	ENOG4108IQI	permease
AFL94_11850	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
AFL94_11855	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AFL94_11860	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
AFL94_11870	ENOG4108097	ATP-binding protein
AFL94_11875	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AFL94_11880	ENOG41080FJ	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
AFL94_11885	ENOG4105CS9	pantothenic acid kinase
AFL94_11890	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AFL94_11895	ENOG41082KK	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
AFL94_11900	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AFL94_11925	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
AFL94_11930	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AFL94_11935	ENOG4108UJD	30S ribosomal protein S9
AFL94_11940	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
AFL94_11945	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AFL94_11955	ENOG4108ZT0	50S ribosomal protein l17
AFL94_11960	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AFL94_11965	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
AFL94_11970	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AFL94_11975	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
AFL94_11985	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
AFL94_11990	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
AFL94_12000	ENOG410849U	50S ribosomal protein L30
AFL94_12005	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
AFL94_12010	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
AFL94_12015	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
AFL94_12020	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AFL94_12025	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AFL94_12030	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
AFL94_12035	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
AFL94_12060	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
AFL94_12070	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
AFL94_12075	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AFL94_12080	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
AFL94_12085	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
AFL94_12090	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AFL94_12095	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AFL94_12100	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
AFL94_12105	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AFL94_12110	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AFL94_12120	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AFL94_12125	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AFL94_12130	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
AFL94_12135	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
AFL94_12145	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AFL94_12150	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AFL94_12165	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
AFL94_12170	ENOG4108VZM	50s ribosomal protein L10
AFL94_12175	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AFL94_12180	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AFL94_12185	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
AFL94_12190	ENOG410683Z	Preprotein translocase SecE subunit
AFL94_12240	ENOG4108X6U	May play a role in the intracellular transport of hydrophobic ligands
AFL94_12250	ENOG4107NHD	transcriptional regulator
AFL94_12255	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
AFL94_12260	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
AFL94_12275	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
AFL94_12290	ENOG4107QJH	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
AFL94_12295	ENOG4107R4N	Cell wall formation (By similarity)
AFL94_12300	ENOG4106UW1	Major Facilitator superfamily
AFL94_12310	ENOG410900P	UPF0336 protein
AFL94_12380	ENOG41080RH	Thioredoxin
AFL94_12390	ENOG4108VPT	UPF0234 protein
AFL94_12395	ENOG4105D0M	Protease HtpX homolog
AFL94_12410	ENOG4105C8J	)-transporter
AFL94_12435	ENOG4105E4F	Isochorismate synthase
AFL94_12445	ENOG4105EAD	ABC transporter
AFL94_12450	ENOG4105CDA	abc transporter atp-binding protein
AFL94_12455	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
AFL94_12465	ENOG4107TCW	O-succinylbenzoate synthase
AFL94_12480	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
AFL94_12485	ENOG4105CPP	Dehydrogenase, E1 component
AFL94_12495	ENOG4108ZRZ	Transcriptional regulator (AsnC family)
AFL94_12500	ENOG4108UKI	Enoyl-CoA hydratase
AFL94_12505	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
AFL94_12510	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
AFL94_12515	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
AFL94_12520	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
AFL94_12525	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
AFL94_12530	ENOG4105NQG	DoxX
AFL94_12535	ENOG4105CDA	abc transporter atp-binding protein
AFL94_12540	ENOG4105E5Q	amino acid AbC transporter
AFL94_12550	ENOG4105RHY	Pfam:UPF0157
AFL94_12555	ENOG4108ZJI	phenylacetic acid degradation protein
AFL94_12575	ENOG4105DXM	phenylacetic acid degradation protein
AFL94_12580	ENOG4105KA0	thioesterase Superfamily protein
AFL94_12610	ENOG4106HK8	GPR1 FUN34 yaaH family protein
AFL94_12620	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AFL94_12625	ENOG4105E39	Enoyl-CoA hydratase
AFL94_12630	ENOG4105CHU	acetyl-coa acetyltransferase
AFL94_12635	ENOG4105CSH	Transporter
AFL94_12640	ENOG4107SIQ	Naphthoate synthase
AFL94_12665	ENOG4105CRE	cytochrome C
AFL94_12675	ENOG4107QIV	Cytochrome c biogenesis protein
AFL94_12680	ENOG4105K63	Thioredoxin
AFL94_12685	ENOG4108RH7	phosphoglycerate mutase
AFL94_12695	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
AFL94_12705	ENOG4108RXW	HAD-superfamily subfamily IB hydrolase
AFL94_12715	ENOG4105D82	Glutamate dehydrogenase
AFL94_12720	ENOG4105MHT	Transcriptional regulator, ARSR family
AFL94_12725	ENOG4105DGU	Histone deacetylase
AFL94_12740	ENOG41061H0	Monooxygenase
AFL94_12745	ENOG4105II7	pyrroline-5-carboxylate reductase
AFL94_12750	ENOG4105EY0	Xylose isomerase domain protein TIM barrel
AFL94_12755	ENOG4107R33	ppx gppa phosphatase
AFL94_12760	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AFL94_12780	ENOG4105C72	UPF0176 protein
AFL94_12790	ENOG4108I5C	dEAD DEAH box helicase
AFL94_12835	ENOG4105P8F	nudix hydrolase
AFL94_12845	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AFL94_12855	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
AFL94_12860	ENOG4105C0H	protease
AFL94_12875	ENOG4105KME	endoribonuclease L-psp
AFL94_12880	ENOG4105BZ4	penicillin-binding protein
AFL94_12890	ENOG4105BZ1	(ABC) transporter
AFL94_12895	ENOG4105BZ1	(ABC) transporter
AFL94_12900	ENOG4105C8V	SAICAR synthetase
AFL94_12905	ENOG4105C12	Phosphoribosylglycinamide synthetase
AFL94_12930	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
AFL94_12945	ENOG410836F	Transposase
AFL94_12955	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
AFL94_12965	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AFL94_12980	ENOG410901E	Membrane
AFL94_12985	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
AFL94_12995	ENOG4105KNI	merR family transcriptional Regulator
AFL94_13000	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AFL94_13005	ENOG4108093	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AFL94_13010	ENOG4105CFG	Acts as a chaperone (By similarity)
AFL94_13060	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AFL94_13070	ENOG4108JJB	ABC transporter
AFL94_13075	ENOG4105NSK	ABC superfamily ATP binding cassette transporter membrane protein
AFL94_13085	ENOG4105KJM	monovalent cation h antiporter subunit g
AFL94_13095	ENOG4105SC1	monovalent cation H antiporter subunit E
AFL94_13100	ENOG4108JPZ	Monovalent cation H antiporter subunit D
AFL94_13105	ENOG4105MKQ	Monovalent cation H antiporter subunit C
AFL94_13110	ENOG4105D65	subunit l
AFL94_13120	ENOG4105DHP	deoxycytidine triphosphate deaminase
AFL94_13135	ENOG4107GFK	fumarate
AFL94_13155	ENOG4105EAB	amino acid AbC transporter
AFL94_13160	ENOG4105DRP	amino acid AbC transporter
AFL94_13165	ENOG4105CDA	abc transporter atp-binding protein
AFL94_13170	ENOG4105D7A	ATP-binding protein
AFL94_13180	ENOG4107Y80	Major Facilitator superfamily
AFL94_13205	ENOG41080T7	secreted protein
AFL94_13220	ENOG4108426	dNA-binding protein
AFL94_13225	ENOG4108426	dNA-binding protein
AFL94_13230	ENOG4105CHR	reductase
AFL94_13240	ENOG41080FR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
AFL94_13245	ENOG4105W0E	50S ribosomal protein L33
AFL94_13250	ENOG4105KDC	50s ribosomal protein l28
AFL94_13265	ENOG4105F38	ABC transporter, permease
AFL94_13270	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AFL94_13285	ENOG4105EW9	transcriptional regulator AsnC family
AFL94_13290	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
AFL94_13325	ENOG4105C26	Dehydrogenase
AFL94_13330	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
AFL94_13340	ENOG4105F9E	Shikimate 5-dehydrogenase
AFL94_13405	ENOG4105W1N	transcriptional regulator
AFL94_13420	ENOG4105CJP	fad dependent oxidoreductase
AFL94_13460	ENOG4105CJW	magnesium transporter
AFL94_13470	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AFL94_13480	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
AFL94_13485	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AFL94_13500	ENOG4107R7I	amino acid
AFL94_13515	ENOG4105CHF	Glutathione S-transferase
AFL94_13530	ENOG4105BZ1	(ABC) transporter
AFL94_13540	ENOG4105E0A	ABC, transporter
AFL94_13545	ENOG4105TVJ	transport system, permease
AFL94_13550	ENOG4105DQ5	transport system permease protein
AFL94_13555	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AFL94_13570	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AFL94_13595	ENOG4105JAB	phenazine biosynthesis protein, phzf family
AFL94_13620	ENOG4105C1G	acyl-Coa dehydrogenase
AFL94_13625	ENOG4105CQ7	ATP-dependent helicase
AFL94_13630	ENOG4105U6C	Alpha beta hydrolase fold protein
AFL94_13635	ENOG4105CPC	Aldo Keto reductase
AFL94_13640	ENOG4105C26	Dehydrogenase
AFL94_13660	ENOG4106S2D	Transcriptional regulator
AFL94_13670	ENOG41090A1	ferritin
AFL94_13690	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
AFL94_13700	ENOG4105EN6	Membrane
AFL94_13715	ENOG4105C57	major facilitator superfamily
AFL94_13720	ENOG4105VEQ	Cold shock protein
AFL94_13725	ENOG4105DEN	Luciferase family
AFL94_13750	ENOG4105DUM	transcriptional regulator, lysR family
AFL94_13760	ENOG4105CBC	glutamate synthase
AFL94_13765	ENOG4105BZ1	(ABC) transporter
AFL94_13770	ENOG4108JJ9	ABC, transporter
AFL94_13780	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
AFL94_13790	ENOG4105BZU	Histidine kinase
AFL94_13795	ENOG4105WH1	Two component transcriptional regulator luxr family
AFL94_13800	ENOG4108IUX	(ABC) transporter
AFL94_13830	ENOG4105KV4	Transcriptional regulator
AFL94_13845	ENOG4105C26	Dehydrogenase
AFL94_13855	ENOG4105CK7	Sodium proline symporter
AFL94_13890	ENOG410667J	hydrolase
AFL94_13930	ENOG4105KXX	peptidase s58 dmpa
AFL94_13955	ENOG4105CPQ	Dehydrogenase
AFL94_13960	ENOG4105CHR	reductase
AFL94_13980	ENOG4105F27	Major Facilitator
AFL94_13990	ENOG4105CF1	Alkylated DNA repair protein
AFL94_13995	ENOG4108KPW	sugar kinase
AFL94_14025	ENOG4105C84	Histidine ammonia-lyase
AFL94_14030	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
AFL94_14050	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
AFL94_14055	ENOG4108RVA	ribokinase
AFL94_14060	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
AFL94_14065	ENOG4105CNN	ABC, transporter
AFL94_14070	ENOG4105C2J	ABC transporter
AFL94_14075	ENOG4105ETE	Transcriptional regulator (LacI family
AFL94_14080	ENOG4107R5H	iron (metal) dependent repressor, dtxr family
AFL94_14090	ENOG4105CZE	histidine utilization repressor
AFL94_14110	ENOG4105S7S	phosphonate abc transporter
AFL94_14150	ENOG4107TXC	Transcriptional regulator
AFL94_14210	ENOG4107ZYR	domain protein
AFL94_14215	ENOG4105CZN	Potassium uptake protein
AFL94_14245	ENOG4105VQD	rieske 2fe-2S domain-containing protein
AFL94_14280	ENOG4105FDP	GntR family transcriptional regulator
AFL94_14285	ENOG4105DAA	L-lactate
AFL94_14290	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
AFL94_14295	ENOG4107QR9	Iron-sulfur cluster binding protein
AFL94_14300	ENOG41080R8	Conserved Protein
AFL94_14325	ENOG4105E90	ABC transporter
AFL94_14330	ENOG4108IJ8	ABC transporter
AFL94_14335	ENOG4105E90	ABC transporter
AFL94_14340	ENOG4105ERH	Fumarylacetoacetate hydrolase
AFL94_14345	ENOG4105BZG	amino acid carrier protein
AFL94_14350	ENOG4105CI0	Citrate lyase
AFL94_14380	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AFL94_14390	ENOG4108ZJI	phenylacetic acid degradation protein
AFL94_14395	ENOG4107HP6	Transcriptional regulator
AFL94_14400	ENOG4107TRN	Xylose isomerase domain protein TIM barrel
AFL94_14405	ENOG4107S9B	Shikimate dehydrogenase
AFL94_14410	ENOG4105CSH	Transporter
AFL94_14425	ENOG4108R4R	Iron-regulated virulence regulatory protein
AFL94_14435	ENOG4108M0I	Transcriptional regulator
AFL94_14440	ENOG4107ZR7	Membrane
AFL94_14455	ENOG4105C1G	acyl-Coa dehydrogenase
AFL94_14460	ENOG4105VG5	Membrane
AFL94_14465	ENOG4105JP4	Inner membrane protein yidG
AFL94_14475	ENOG4105CSH	Transporter
AFL94_14480	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
AFL94_14485	ENOG4105KVH	Transcriptional regulator
AFL94_14495	ENOG4105DEF	Extracellular solute-binding protein, family 5
AFL94_14505	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AFL94_14525	ENOG4105CEY	Amp-dependent synthetase and ligase
AFL94_14540	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AFL94_14595	ENOG4107258	Transcriptional regulator
AFL94_14615	ENOG4105CHU	acetyl-coa acetyltransferase
AFL94_14620	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AFL94_14625	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
AFL94_14630	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AFL94_14635	ENOG4105C7K	acetolactate synthase
AFL94_14650	ENOG4107YCY	Transcriptional regulator
AFL94_14660	ENOG4108IJ0	Aspartate ammonia-lyase
AFL94_14670	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
AFL94_14695	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
AFL94_14700	ENOG4105CPP	Dehydrogenase, E1 component
AFL94_14710	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AFL94_14715	ENOG41082T9	Membrane
AFL94_14730	ENOG4107QTF	adenylosuccinate lyase
AFL94_14735	ENOG4107QND	Nitrite extrusion protein
AFL94_14740	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
AFL94_14745	ENOG4107QZF	nitrite reductase NADPH large subunit
AFL94_14755	ENOG4107QZF	nitrite reductase NADPH large subunit
AFL94_14760	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AFL94_14770	ENOG4105CPC	Aldo Keto reductase
AFL94_14780	ENOG4105CQB	FAD linked oxidase domain protein
AFL94_14800	ENOG4105C2W	permease
AFL94_14810	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
AFL94_14825	ENOG4105CEY	Amp-dependent synthetase and ligase
AFL94_14845	ENOG4105BZU	Histidine kinase
AFL94_14855	ENOG4108M15	ABC transporter
AFL94_14880	ENOG4105CI2	imidazolone-5-propionate hydrolase
AFL94_14900	ENOG4105CHM	Aminotransferase
AFL94_14905	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
AFL94_14920	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AFL94_14925	ENOG4105QPS	Monooxygenase
AFL94_14930	ENOG4105DXX	methyltransferase
AFL94_14970	ENOG4105DWY	Agmatine deiminase
AFL94_14975	ENOG4107QPI	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
AFL94_15015	ENOG4105CSV	Glutaminase
AFL94_15020	ENOG4105NAU	thioesterase Superfamily protein
AFL94_15045	ENOG4105BZU	Histidine kinase
AFL94_15085	ENOG4105QPS	Monooxygenase
AFL94_15110	ENOG4105DJ2	Major Facilitator Superfamily
AFL94_15135	ENOG4105VPX	protein, conserved in bacteria
AFL94_15150	ENOG4105ME7	Membrane
AFL94_15160	ENOG4105C85	amino acid
AFL94_15170	ENOG4105NAE	bifunctional deaminase-reductase domain protein
AFL94_15175	ENOG4107QTZ	amino acid
AFL94_15180	ENOG4105KZX	Pterin carbinolamine dehydratase
AFL94_15200	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
AFL94_15205	ENOG4105CUB	amino acid
AFL94_15225	ENOG4105CSH	Transporter
AFL94_15235	ENOG4105UQX	Mate efflux family protein
AFL94_15245	ENOG4105D94	Major Facilitator Superfamily
AFL94_15250	ENOG4108TYN	CAAX amino terminal protease family protein
AFL94_15260	ENOG4105DEF	Extracellular solute-binding protein, family 5
AFL94_15265	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AFL94_15270	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AFL94_15280	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
AFL94_15295	ENOG4106NZI	LysR family Transcriptional regulator
AFL94_15305	ENOG4105C10	Electron transfer flavoprotein
AFL94_15345	ENOG4108RK3	acyl-Coa dehydrogenase
AFL94_15350	ENOG4105X7H	acyl-CoA dehydrogenase
AFL94_15395	ENOG4105C26	Dehydrogenase
AFL94_15415	ENOG4108SGK	Tetr family transcriptional regulator
AFL94_15420	ENOG4105CD5	CoA-binding domain protein
AFL94_15425	ENOG4105D2B	acyl-CoA dehydrogenase
AFL94_15455	ENOG4105D0M	Protease HtpX homolog
AFL94_15465	ENOG41080UQ	Transcriptional regulator
AFL94_15470	ENOG4105CSH	Transporter
AFL94_15475	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
AFL94_15480	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AFL94_15495	ENOG4108ZCD	Transcriptional coactivator pterin dehydratase
AFL94_15505	ENOG4105H67	Protein of unknown function (DUF421)
AFL94_15510	ENOG4107RY6	amino acid
AFL94_15520	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
AFL94_15540	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
AFL94_15555	ENOG4105FDF	Could be involved in DNA repair (By similarity)
AFL94_15560	ENOG4105DQE	DNA ligase
AFL94_15570	ENOG4105C26	Dehydrogenase
AFL94_15580	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
AFL94_15595	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
AFL94_15620	ENOG4105C26	Dehydrogenase
AFL94_15625	ENOG4105C7K	acetolactate synthase
AFL94_15635	ENOG4105DUM	transcriptional regulator, lysR family
AFL94_15640	ENOG4105CSH	Transporter
AFL94_15650	ENOG4105G9B	Transcriptional regulator
AFL94_15740	ENOG4108JJB	ABC transporter
AFL94_15770	ENOG4105CKU	formyltetrahydrofolate synthetase
AFL94_15790	ENOG4107258	Transcriptional regulator
AFL94_15800	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
AFL94_15810	ENOG4105CHR	reductase
AFL94_15835	ENOG4105CSV	Glutaminase
AFL94_15875	ENOG4105EXC	Acyl-transferase
AFL94_15885	ENOG4108PYU	two-component system response regulator
AFL94_15890	ENOG4108FKE	two-component system sensor kinase
AFL94_15905	ENOG4107ZR7	Membrane
AFL94_15925	ENOG4107S2Z	UPF0761 membrane protein
AFL94_15940	ENOG41060W2	glyoxylate carboligase
AFL94_15945	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
AFL94_15950	ENOG4107TFQ	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
AFL94_15955	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
AFL94_15960	ENOG410633P	Hydantoin racemase
AFL94_15985	ENOG4108MES	Periplasmic binding protein
AFL94_15995	ENOG4105CM4	permease protein
AFL94_16000	ENOG4108IPW	abc transporter atp-binding protein
AFL94_16020	ENOG4105CC5	ABC transporter
AFL94_16025	ENOG4105FDK	ABC transporter
AFL94_16045	ENOG4107QX3	carboxylase
AFL94_16100	ENOG4105BZW	Glycerate kinase
AFL94_16115	ENOG4105CHH	sulfate transporter
AFL94_16125	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
AFL94_16140	ENOG4105CEY	Amp-dependent synthetase and ligase
AFL94_16210	ENOG4105C94	Transporter
AFL94_16220	ENOG4105CSH	Transporter
AFL94_16225	ENOG4105CSH	Transporter
AFL94_16230	ENOG4107258	Transcriptional regulator
AFL94_16240	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
AFL94_16245	ENOG4105DKQ	ROK family
AFL94_16250	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AFL94_16255	ENOG4108JQ7	(ABC) transporter
AFL94_16260	ENOG4105C3U	ABC transporter
AFL94_16265	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AFL94_16270	ENOG4105DEF	Extracellular solute-binding protein, family 5
AFL94_16275	ENOG41073TP	transcriptional regulator
AFL94_16285	ENOG4105C10	Electron transfer flavoprotein
AFL94_16305	ENOG41069M3	Transcriptional regulator
AFL94_16310	ENOG4105IKQ	hydratase
AFL94_16315	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
AFL94_16320	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
AFL94_16350	ENOG4105C10	Electron transfer flavoprotein
AFL94_16370	ENOG4105E39	Enoyl-CoA hydratase
AFL94_16385	ENOG4105EA8	2-Nitropropane dioxygenase
AFL94_16405	ENOG41080V3	Major Facilitator superfamily
AFL94_16410	ENOG4105F2C	Acetyl-CoA acetyltransferase
AFL94_16420	ENOG4105CC9	acyl-Coa dehydrogenase
AFL94_16430	ENOG4105D2B	acyl-CoA dehydrogenase
AFL94_16435	ENOG4105D2B	acyl-CoA dehydrogenase
AFL94_16440	ENOG4108KC2	acyl-Coa dehydrogenase
AFL94_16465	ENOG4105CHU	acetyl-coa acetyltransferase
AFL94_16485	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AFL94_16570	ENOG4105E4C	Lytic transglycosylase catalytic
AFL94_16595	ENOG4105CDU	Replicative dna helicase
AFL94_16605	ENOG4105C57	major facilitator superfamily
AFL94_16620	ENOG4105EUB	pirin domain protein
AFL94_16625	ENOG4105K56	Transcriptional regulator
AFL94_16640	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
AFL94_16675	ENOG4105VT2	5-hydroxyisourate hydrolase
AFL94_16685	ENOG4105C2W	permease
AFL94_16705	ENOG4105CUB	amino acid
AFL94_16730	ENOG4105EMU	Dehydrogenase
AFL94_16745	ENOG4105DXB	Major Facilitator superfamily
AFL94_16750	ENOG4105C85	amino acid
AFL94_16760	ENOG4105DKQ	ROK family
AFL94_16770	ENOG4105D9R	oxidoreductase
AFL94_16780	ENOG4105D7K	pfkb domain protein
AFL94_16790	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
AFL94_16795	ENOG4105C26	Dehydrogenase
AFL94_16805	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
AFL94_16810	ENOG4105F0H	myo-inositol catabolism protein
AFL94_16815	ENOG4107QNK	)-transporter
AFL94_16820	ENOG4105SHT	UspA domain-containing protein
AFL94_16830	ENOG4105ETE	Transcriptional regulator (LacI family
AFL94_16835	ENOG4105CK5	oxidoreductase
AFL94_16845	ENOG4105DH8	myo-inositol catabolism
AFL94_16850	ENOG4105FDP	GntR family transcriptional regulator
AFL94_16860	ENOG41060NJ	transcriptional regulator
AFL94_16870	ENOG41062B0	ABC transporter, permease
AFL94_16875	ENOG4105C2J	ABC transporter
AFL94_16880	ENOG4105ETE	Transcriptional regulator (LacI family
AFL94_16885	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
AFL94_16890	ENOG4105CK5	oxidoreductase
AFL94_16900	ENOG4105CK5	oxidoreductase
AFL94_16920	ENOG4105BZ1	(ABC) transporter
AFL94_16925	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
AFL94_16945	ENOG4107R9S	Malate synthase
AFL94_16955	ENOG4105S0E	allantoin catabolism protein
AFL94_16970	ENOG4105H37	Glyoxalase Bleomycin resistance protein (Dioxygenase
AFL94_16985	ENOG41088PD	hydrolase
AFL94_16990	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
AFL94_17015	ENOG4105CEY	Amp-dependent synthetase and ligase
AFL94_17025	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AFL94_17055	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
AFL94_17060	ENOG4105CSH	Transporter
AFL94_17115	ENOG4108RZE	Tetr family transcriptional regulator
AFL94_17120	ENOG4105D74	hydrolase
AFL94_17130	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AFL94_17145	ENOG4105CHR	reductase
AFL94_17160	ENOG4105CHU	acetyl-coa acetyltransferase
AFL94_17185	ENOG410836F	Transposase
AFL94_17190	ENOG410836F	Transposase
AFL94_17210	ENOG4105MP0	transposase
AFL94_17285	ENOG4107QME	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
AFL94_17290	ENOG41084HI	prevent-host-death family
AFL94_17330	ENOG4105CBD	Diacylglycerol kinase
AFL94_17355	ENOG4105CEY	Amp-dependent synthetase and ligase
AFL94_17405	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
AFL94_17410	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
AFL94_17420	ENOG410829C	Binds together with S18 to 16S ribosomal RNA (By similarity)
AFL94_17425	ENOG4105EXC	Acyl-transferase
AFL94_17430	ENOG4105D5U	fad dependent oxidoreductase
AFL94_17445	ENOG4105DFM	M18 family aminopeptidase
AFL94_17455	ENOG4105WH1	Two component transcriptional regulator luxr family
AFL94_17460	ENOG4105BZU	Histidine kinase
AFL94_17495	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AFL94_17525	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
AFL94_17555	ENOG4105C2J	ABC transporter
AFL94_17560	ENOG4105CNN	ABC, transporter
AFL94_17570	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AFL94_17575	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
AFL94_17580	ENOG4105CHU	acetyl-coa acetyltransferase
AFL94_17585	ENOG4108JGH	Tetr family transcriptional regulator
AFL94_17600	ENOG4108WFR	AraC Family Transcriptional Regulator
AFL94_17625	ENOG4105CHR	reductase
AFL94_17650	ENOG4105F0R	Cytidylyltransferase
AFL94_17655	ENOG4105D2T	synthase
AFL94_17680	ENOG4105CZA	synthase
AFL94_17685	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AFL94_17705	ENOG4105C3M	thioredoxin reductase
AFL94_17710	ENOG4105K63	Thioredoxin
AFL94_17720	ENOG4105FA0	parb-like partition protein
AFL94_17725	ENOG4107QJE	Chromosome Partitioning Protein
AFL94_17730	ENOG4107XUG	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
AFL94_17740	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AFL94_17745	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)