locus-tag	class	description
NicSoilB11_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NicSoilB11_00020	COG0592	DNA-directed DNA polymerase activity
NicSoilB11_00030	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
NicSoilB11_00040	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NicSoilB11_00050	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
NicSoilB11_00060	COG0187	DNA topoisomerase II activity
NicSoilB11_00070	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NicSoilB11_00090	COG3266	domain, Protein
NicSoilB11_00150	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NicSoilB11_00160	COG2818	Glycosylase
NicSoilB11_00180	COG3764	Sortase (surface protein transpeptidase)
NicSoilB11_00210	COG0515	serine threonine protein kinase
NicSoilB11_00210	COG2815	serine threonine protein kinase
NicSoilB11_00220	COG0515	serine threonine protein kinase
NicSoilB11_00260	COG1716	ATPase activity
NicSoilB11_00270	COG1716	ATPase activity
NicSoilB11_00360	COG0431	NADPH-dependent FMN reductase
NicSoilB11_00370	COG0346	lactoylglutathione lyase activity
NicSoilB11_00460	COG0277	FAD linked oxidase domain protein
NicSoilB11_00470	COG1357	PFAM Pentapeptide repeats (8 copies)
NicSoilB11_00480	COG0154	amidase activity
NicSoilB11_00490	COG2957	Belongs to the agmatine deiminase family
NicSoilB11_00510	COG1162	GTPase activity
NicSoilB11_00530	COG3706	GGDEF domain
NicSoilB11_00570	COG0673	inositol 2-dehydrogenase activity
NicSoilB11_00590	COG1175	transmembrane transport
NicSoilB11_00600	COG1653	transport
NicSoilB11_00620	COG4948	Mandelate Racemase Muconate Lactonizing
NicSoilB11_00640	COG1609	Transcriptional regulator
NicSoilB11_00650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NicSoilB11_00660	COG0765	amino acid transport
NicSoilB11_00670	COG1126	abc transporter atp-binding protein
NicSoilB11_00680	COG0673	inositol 2-dehydrogenase activity
NicSoilB11_00700	COG0659	secondary active sulfate transmembrane transporter activity
NicSoilB11_00760	COG2084	Dehydrogenase
NicSoilB11_00840	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NicSoilB11_00950	COG0477	Major facilitator Superfamily
NicSoilB11_00970	COG0179	Fumarylacetoacetate (FAA) hydrolase
NicSoilB11_00980	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NicSoilB11_01080	COG0515	serine threonine protein kinase
NicSoilB11_01080	COG2815	serine threonine protein kinase
NicSoilB11_01140	COG1609	Transcriptional regulator
NicSoilB11_01150	COG1957	nucleoside hydrolase
NicSoilB11_01160	COG0477	Major facilitator Superfamily
NicSoilB11_01170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NicSoilB11_01180	COG1609	Transcriptional regulator
NicSoilB11_01190	COG0395	ABC-type sugar transport system, permease component
NicSoilB11_01200	COG1175	transmembrane transport
NicSoilB11_01230	COG1621	beta-fructofuranosidase activity
NicSoilB11_01240	COG1028	Short-chain dehydrogenase reductase Sdr
NicSoilB11_01340	COG0395	ABC-type sugar transport system, permease component
NicSoilB11_01350	COG3622	Belongs to the hyi family
NicSoilB11_01420	COG0673	inositol 2-dehydrogenase activity
NicSoilB11_01460	COG1940	carbohydrate kinase activity
NicSoilB11_01470	COG0673	inositol 2-dehydrogenase activity
NicSoilB11_01490	COG0477	Major facilitator Superfamily
NicSoilB11_01510	COG0583	DNA-binding transcription factor activity
NicSoilB11_01530	COG1028	Short-chain dehydrogenase reductase Sdr
NicSoilB11_01550	COG0179	Fumarylacetoacetate (FAA) hydrolase
NicSoilB11_01570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NicSoilB11_01590	COG0179	Fumarylacetoacetate (FAA) hydrolase
NicSoilB11_01630	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NicSoilB11_01650	COG0561	phosphatase activity
NicSoilB11_01670	COG0584	glycerophosphoryl diester phosphodiesterase
NicSoilB11_01700	COG2200	EAL domain
NicSoilB11_01700	COG2199	diguanylate cyclase activity
NicSoilB11_01720	COG5002	protein histidine kinase activity
NicSoilB11_01750	COG1028	Short-chain dehydrogenase reductase Sdr
NicSoilB11_01760	COG1929	Belongs to the glycerate kinase type-1 family
NicSoilB11_01790	COG1028	Short-chain dehydrogenase reductase Sdr
NicSoilB11_01820	COG0823	Involved in the tonB-independent uptake of proteins
NicSoilB11_01840	COG0673	inositol 2-dehydrogenase activity
NicSoilB11_01850	COG0673	inositol 2-dehydrogenase activity
NicSoilB11_01870	COG0395	ABC-type sugar transport system, permease component
NicSoilB11_01960	COG2233	PERMEase
NicSoilB11_01970	COG0778	Nitroreductase
NicSoilB11_02010	COG0583	DNA-binding transcription factor activity
NicSoilB11_02040	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
NicSoilB11_02050	COG2186	Transcriptional regulator
NicSoilB11_02070	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NicSoilB11_02100	COG5416	Lipopolysaccharide assembly protein A domain
NicSoilB11_02140	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NicSoilB11_02170	COG1597	lipid kinase activity
NicSoilB11_02180	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NicSoilB11_02210	COG0561	phosphatase activity
NicSoilB11_02240	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
NicSoilB11_02300	COG0037	tRNA processing
NicSoilB11_02320	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NicSoilB11_02330	COG0302	gtp cyclohydrolase
NicSoilB11_02340	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NicSoilB11_02350	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NicSoilB11_02410	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NicSoilB11_02460	COG0693	protein deglycase activity
NicSoilB11_02470	COG2814	Major facilitator Superfamily
NicSoilB11_02490	COG1309	transcriptional regulator
NicSoilB11_02520	COG3665	Urea carboxylase-associated protein
NicSoilB11_02570	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NicSoilB11_02620	COG0823	Involved in the tonB-independent uptake of proteins
NicSoilB11_02620	COG1506	peptidase
NicSoilB11_02630	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
NicSoilB11_02640	COG2376	Dihydroxyacetone kinase
NicSoilB11_02650	COG1461	Dihydroxyacetone kinase
NicSoilB11_02660	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
NicSoilB11_02720	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NicSoilB11_02750	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NicSoilB11_02780	COG4948	Mandelate Racemase Muconate Lactonizing
NicSoilB11_02800	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NicSoilB11_02810	COG0583	DNA-binding transcription factor activity
NicSoilB11_02850	COG0589	response to stress
NicSoilB11_02880	COG5002	protein histidine kinase activity
NicSoilB11_02940	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NicSoilB11_02970	COG0306	phosphate transporter
NicSoilB11_03030	COG1609	Transcriptional regulator
NicSoilB11_03060	COG1595	DNA-templated transcription, initiation
NicSoilB11_03110	COG1609	Transcriptional regulator
NicSoilB11_03120	COG1335	isochorismatase
NicSoilB11_03130	COG0831	urea catabolic process
NicSoilB11_03140	COG0832	Belongs to the urease beta subunit family
NicSoilB11_03150	COG0804	urea catabolic process
NicSoilB11_03160	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
NicSoilB11_03170	COG0830	nickel cation binding
NicSoilB11_03180	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NicSoilB11_03190	COG0829	nickel cation binding
NicSoilB11_03200	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
NicSoilB11_03300	COG3958	Transketolase
NicSoilB11_03310	COG3959	Transketolase, thiamine diphosphate binding domain
NicSoilB11_03320	COG0477	Major facilitator Superfamily
NicSoilB11_03340	COG1028	Short-chain dehydrogenase reductase Sdr
NicSoilB11_03350	COG2376	Dihydroxyacetone kinase
NicSoilB11_03360	COG0698	ribose 5-phosphate isomerase
NicSoilB11_03390	COG0402	S-adenosylhomocysteine deaminase activity
NicSoilB11_03410	COG2272	Belongs to the type-B carboxylesterase lipase family
NicSoilB11_03480	COG2723	6-phospho-beta-galactosidase activity
NicSoilB11_03530	COG3250	beta-galactosidase activity
NicSoilB11_03580	COG1414	Transcriptional regulator
NicSoilB11_03590	COG3250	beta-galactosidase activity
NicSoilB11_03640	COG1175	transmembrane transport
NicSoilB11_03650	COG0395	ABC-type sugar transport system, permease component
NicSoilB11_03660	COG4948	Mandelate Racemase Muconate Lactonizing
NicSoilB11_03670	COG0800	Aldolase
NicSoilB11_03690	COG4948	Mandelate Racemase Muconate Lactonizing
NicSoilB11_03710	COG0477	Major facilitator Superfamily
NicSoilB11_03720	COG0477	Major facilitator Superfamily
NicSoilB11_03760	COG1028	Short-chain dehydrogenase reductase Sdr
NicSoilB11_03780	COG1960	acyl-CoA dehydrogenase activity
NicSoilB11_03800	COG0477	Major facilitator Superfamily
NicSoilB11_03820	COG0385	Bile acid
NicSoilB11_03830	COG0243	molybdopterin cofactor binding
NicSoilB11_03860	COG0657	acetylesterase activity
NicSoilB11_03870	COG0179	Fumarylacetoacetate (FAA) hydrolase
NicSoilB11_03880	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NicSoilB11_03920	COG1028	Short-chain dehydrogenase reductase Sdr
NicSoilB11_03950	COG0436	Aminotransferase
NicSoilB11_03960	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NicSoilB11_03980	COG0583	DNA-binding transcription factor activity
NicSoilB11_03990	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NicSoilB11_04000	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NicSoilB11_04010	COG1984	allophanate hydrolase subunit 2
NicSoilB11_04020	COG4221	oxidoreductase activity
NicSoilB11_04030	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NicSoilB11_04040	COG1028	Short-chain dehydrogenase reductase Sdr
NicSoilB11_04050	COG1063	alcohol dehydrogenase
NicSoilB11_04060	COG3265	gluconokinase activity
NicSoilB11_04080	COG0697	spore germination
NicSoilB11_04100	COG0667	Aldo Keto reductase
NicSoilB11_04160	COG2890	protein-(glutamine-N5) methyltransferase activity
NicSoilB11_04200	COG0656	L-ascorbic acid biosynthetic process
NicSoilB11_04210	COG0318	PFAM AMP-dependent synthetase and ligase
NicSoilB11_04220	COG0183	Belongs to the thiolase family
NicSoilB11_04230	COG1960	acyl-CoA dehydrogenase activity
NicSoilB11_04240	COG1309	transcriptional regulator
NicSoilB11_04260	COG0667	Aldo Keto reductase
NicSoilB11_04270	COG0656	L-ascorbic acid biosynthetic process
NicSoilB11_04300	COG3360	Dodecin
NicSoilB11_04310	COG2186	Transcriptional regulator
NicSoilB11_04330	COG2084	Dehydrogenase
NicSoilB11_04340	COG2610	gluconate transmembrane transporter activity
NicSoilB11_04400	COG0300	oxidoreductase activity
NicSoilB11_04420	COG0477	Major facilitator Superfamily
NicSoilB11_04440	COG1793	dna ligase
NicSoilB11_04440	COG3285	dna ligase
NicSoilB11_04450	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NicSoilB11_04490	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NicSoilB11_04490	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NicSoilB11_04490	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NicSoilB11_04500	COG1105	Belongs to the carbohydrate kinase PfkB family
NicSoilB11_04510	COG1349	DNA-binding transcription factor activity
NicSoilB11_04540	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NicSoilB11_04560	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NicSoilB11_04580	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NicSoilB11_04590	COG0509	glycine decarboxylation via glycine cleavage system
NicSoilB11_04600	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NicSoilB11_04610	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NicSoilB11_04610	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NicSoilB11_04620	COG1113	amino acid transport
NicSoilB11_04640	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NicSoilB11_04660	COG2733	membrane
NicSoilB11_04680	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NicSoilB11_04770	COG4122	O-methyltransferase activity
NicSoilB11_04870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NicSoilB11_04880	COG1191	sigma factor activity
NicSoilB11_04890	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NicSoilB11_04920	COG0297	glycogen (starch) synthase activity
NicSoilB11_04930	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
NicSoilB11_04940	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NicSoilB11_04940	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NicSoilB11_04970	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NicSoilB11_04970	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NicSoilB11_04990	COG0583	DNA-binding transcription factor activity
NicSoilB11_05010	COG1028	Short-chain dehydrogenase reductase Sdr
NicSoilB11_05030	COG1733	regulation of RNA biosynthetic process
NicSoilB11_05040	COG0702	epimerase
NicSoilB11_05050	COG1280	lysine exporter protein (LysE YggA)
NicSoilB11_05080	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NicSoilB11_05120	COG0179	Fumarylacetoacetate (FAA) hydrolase
NicSoilB11_05130	COG0589	response to stress
NicSoilB11_05170	COG3290	protein histidine kinase activity
NicSoilB11_05180	COG4565	transcriptional regulatory protein
NicSoilB11_05190	COG0010	Belongs to the arginase family
NicSoilB11_05200	COG3263	regulation of cellular component size
NicSoilB11_05210	COG2252	PERMEase
NicSoilB11_05250	COG3848	Pyruvate phosphate dikinase
NicSoilB11_05250	COG0574	Belongs to the PEP-utilizing enzyme family
NicSoilB11_05290	COG0791	NLP P60 protein
NicSoilB11_05290	COG3883	PFAM NLP P60 protein
NicSoilB11_05320	COG0697	spore germination
NicSoilB11_05330	COG1796	DNA polymerase
NicSoilB11_05330	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NicSoilB11_05410	COG0366	Alpha amylase catalytic
NicSoilB11_05460	COG1609	Transcriptional regulator
NicSoilB11_05490	COG1024	Enoyl-CoA hydratase
NicSoilB11_05530	COG0789	Transcriptional regulator
NicSoilB11_05550	COG1278	Cold shock
NicSoilB11_05560	COG2197	response regulator
NicSoilB11_05570	COG4585	Histidine kinase
NicSoilB11_05590	COG0183	Belongs to the thiolase family
NicSoilB11_05610	COG2031	fatty acid transporter
NicSoilB11_05620	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NicSoilB11_05640	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NicSoilB11_05650	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NicSoilB11_05700	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NicSoilB11_05700	COG0357	Ribosomal RNA small subunit methyltransferase G
NicSoilB11_05710	COG0191	fructose-bisphosphate aldolase activity
NicSoilB11_05810	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NicSoilB11_05860	COG1832	CoA-binding protein
NicSoilB11_05880	COG2315	Protein conserved in bacteria
NicSoilB11_05920	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NicSoilB11_05930	COG0047	phosphoribosylformylglycinamidine synthase activity
NicSoilB11_05960	COG1404	Belongs to the peptidase S8 family
NicSoilB11_06000	COG1846	Transcriptional regulator
NicSoilB11_06050	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NicSoilB11_06100	COG0386	Belongs to the glutathione peroxidase family
NicSoilB11_06110	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NicSoilB11_06160	COG1309	transcriptional regulator
NicSoilB11_06180	COG0438	transferase activity, transferring glycosyl groups
NicSoilB11_06210	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NicSoilB11_06230	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NicSoilB11_06280	COG0642	Histidine kinase
NicSoilB11_06290	COG0745	RESPONSE REGULATOR receiver
NicSoilB11_06300	COG0477	Major facilitator Superfamily
NicSoilB11_06310	COG0028	Belongs to the TPP enzyme family
NicSoilB11_06320	COG0351	phosphomethylpyrimidine kinase
NicSoilB11_06400	COG0343	queuine tRNA-ribosyltransferase activity
NicSoilB11_06460	COG1621	beta-fructofuranosidase activity
NicSoilB11_06490	COG1960	acyl-CoA dehydrogenase activity
NicSoilB11_06520	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NicSoilB11_06540	COG0586	Pfam SNARE associated Golgi protein
NicSoilB11_06560	COG0564	pseudouridine synthase activity
NicSoilB11_06600	COG2364	Membrane
NicSoilB11_06610	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NicSoilB11_06620	COG1201	RNA secondary structure unwinding
NicSoilB11_06630	COG0723	plastoquinol--plastocyanin reductase activity
NicSoilB11_06640	COG0644	oxidoreductase
NicSoilB11_06710	COG0028	Belongs to the TPP enzyme family
NicSoilB11_06730	COG2066	Belongs to the glutaminase family
NicSoilB11_06760	COG0179	Fumarylacetoacetate (FAA) hydrolase
NicSoilB11_06790	COG2814	Major facilitator Superfamily
NicSoilB11_06800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NicSoilB11_06810	COG1609	Transcriptional regulator
NicSoilB11_06830	COG1175	transmembrane transport
NicSoilB11_06840	COG0395	ABC-type sugar transport system, permease component
NicSoilB11_06860	COG0673	inositol 2-dehydrogenase activity
NicSoilB11_06880	COG1904	glucuronate isomerase
NicSoilB11_06890	COG0246	Mannitol dehydrogenase
NicSoilB11_06910	COG4948	Mandelate Racemase Muconate Lactonizing
NicSoilB11_06950	COG1063	alcohol dehydrogenase
NicSoilB11_07010	COG0671	phosphoesterase, PA-phosphatase related
NicSoilB11_07020	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NicSoilB11_07050	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NicSoilB11_07060	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NicSoilB11_07080	COG2205	protein histidine kinase activity
NicSoilB11_07090	COG0745	RESPONSE REGULATOR receiver
NicSoilB11_07120	COG2062	phosphohistidine phosphatase, SixA
NicSoilB11_07130	COG0583	DNA-binding transcription factor activity
NicSoilB11_07150	COG1309	transcriptional regulator
NicSoilB11_07160	COG1511	domain protein
NicSoilB11_07190	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
NicSoilB11_07200	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NicSoilB11_07200	COG1017	nitric oxide dioxygenase activity
NicSoilB11_07230	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NicSoilB11_07240	COG0514	ATP-dependent DNA helicase (RecQ)
NicSoilB11_07260	COG1505	serine-type exopeptidase activity
NicSoilB11_07280	COG3321	synthase
NicSoilB11_07280	COG0604	alcohol dehydrogenase
NicSoilB11_07280	COG1028	Short-chain dehydrogenase reductase Sdr
NicSoilB11_07300	COG0577	efflux transmembrane transporter activity
NicSoilB11_07300	COG1136	(ABC) transporter
NicSoilB11_07330	COG1966	Carbon starvation protein
NicSoilB11_07370	COG0656	L-ascorbic acid biosynthetic process
NicSoilB11_07410	COG1252	NADH dehydrogenase
NicSoilB11_07450	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NicSoilB11_07460	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NicSoilB11_07500	COG0588	phosphoglycerate mutase activity
NicSoilB11_07520	COG5002	protein histidine kinase activity
NicSoilB11_07560	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NicSoilB11_07570	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NicSoilB11_07580	COG0215	cysteine-tRNA ligase activity
NicSoilB11_07630	COG0028	Belongs to the TPP enzyme family
NicSoilB11_07660	COG0366	Alpha amylase catalytic
NicSoilB11_07680	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NicSoilB11_07710	COG0366	Alpha amylase catalytic
NicSoilB11_07720	COG0277	FAD linked oxidase domain protein
NicSoilB11_07740	COG3842	ATPase activity
NicSoilB11_07760	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
NicSoilB11_07810	COG4214	carbohydrate transport
NicSoilB11_07820	COG1129	ABC transporter
NicSoilB11_07830	COG4213	ABC transporter substrate-binding protein
NicSoilB11_07860	COG2160	L-arabinose isomerase activity
NicSoilB11_07870	COG1609	Transcriptional regulator
NicSoilB11_07920	COG0783	Belongs to the Dps family
NicSoilB11_07930	COG0477	Major facilitator Superfamily
NicSoilB11_07950	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NicSoilB11_07950	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NicSoilB11_07960	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NicSoilB11_08030	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NicSoilB11_08060	COG1278	Cold shock
NicSoilB11_08080	COG0459	protein refolding
NicSoilB11_08090	COG1653	transport
NicSoilB11_08100	COG0328	RNA-DNA hybrid ribonuclease activity
NicSoilB11_08120	COG2205	protein histidine kinase activity
NicSoilB11_08130	COG0745	RESPONSE REGULATOR receiver
NicSoilB11_08170	COG1061	Type III restriction enzyme res subunit
NicSoilB11_08200	COG1278	Cold shock
NicSoilB11_08240	COG0739	heme binding
NicSoilB11_08250	COG1388	LysM domain
NicSoilB11_08250	COG3103	Sh3 type 3 domain protein
NicSoilB11_08250	COG0791	NLP P60 protein
NicSoilB11_08280	COG0746	molybdenum cofactor guanylyltransferase activity
NicSoilB11_08310	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NicSoilB11_08350	COG0488	(ABC) transporter
NicSoilB11_08360	COG1132	(ABC) transporter
NicSoilB11_08410	COG0483	inositol monophosphate 1-phosphatase activity
NicSoilB11_08440	COG0045	succinate-CoA ligase (ADP-forming) activity
NicSoilB11_08480	COG1028	Short-chain dehydrogenase reductase Sdr
NicSoilB11_08500	COG1082	Xylose isomerase domain protein TIM barrel
NicSoilB11_08510	COG2376	Dihydroxyacetone kinase
NicSoilB11_08520	COG0698	ribose 5-phosphate isomerase
NicSoilB11_08530	COG1250	3-hydroxyacyl-CoA dehydrogenase
NicSoilB11_08540	COG1028	Short-chain dehydrogenase reductase Sdr
NicSoilB11_08550	COG2271	Major facilitator Superfamily
NicSoilB11_08580	COG0640	Transcriptional regulator
NicSoilB11_08610	COG3962	Belongs to the TPP enzyme family
NicSoilB11_08640	COG0673	inositol 2-dehydrogenase activity
NicSoilB11_08650	COG2814	Major facilitator Superfamily
NicSoilB11_08650	COG2814	Major facilitator Superfamily
NicSoilB11_08660	COG1846	Transcriptional regulator
NicSoilB11_08670	COG2814	Major facilitator Superfamily
NicSoilB11_08680	COG3718	enzyme involved in inositol metabolism
NicSoilB11_08690	COG2188	Transcriptional regulator
NicSoilB11_08740	COG1396	sequence-specific DNA binding
NicSoilB11_08760	COG0028	Belongs to the TPP enzyme family
NicSoilB11_08780	COG0477	Major facilitator Superfamily
NicSoilB11_08830	COG1401	restriction endodeoxyribonuclease activity
NicSoilB11_08850	COG5002	protein histidine kinase activity
NicSoilB11_08860	COG0745	RESPONSE REGULATOR receiver
NicSoilB11_08900	COG4124	Belongs to the glycosyl hydrolase 26 family
NicSoilB11_08900	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NicSoilB11_08960	COG1902	pentaerythritol trinitrate reductase activity
NicSoilB11_09030	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NicSoilB11_09060	COG3583	domain protein
NicSoilB11_09070	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NicSoilB11_09080	COG0366	Alpha amylase catalytic
NicSoilB11_09080	COG3103	Sh3 type 3 domain protein
NicSoilB11_09090	COG1254	Belongs to the acylphosphatase family
NicSoilB11_09130	COG0477	Major facilitator Superfamily
NicSoilB11_09140	COG1063	alcohol dehydrogenase
NicSoilB11_09170	COG0246	Mannitol dehydrogenase
NicSoilB11_09180	COG0800	Aldolase
NicSoilB11_09200	COG0514	ATP-dependent DNA helicase (RecQ)
NicSoilB11_09240	COG0667	Aldo Keto reductase
NicSoilB11_09250	COG1063	alcohol dehydrogenase
NicSoilB11_09280	COG0477	Major facilitator Superfamily
NicSoilB11_09300	COG1253	flavin adenine dinucleotide binding
NicSoilB11_09320	COG0179	Fumarylacetoacetate (FAA) hydrolase
NicSoilB11_09360	COG4948	Mandelate Racemase Muconate Lactonizing
NicSoilB11_09370	COG2186	Transcriptional regulator
NicSoilB11_09390	COG1175	transmembrane transport
NicSoilB11_09400	COG0395	ABC-type sugar transport system, permease component
NicSoilB11_09420	COG0640	Transcriptional regulator
NicSoilB11_09500	COG1012	belongs to the aldehyde dehydrogenase family
NicSoilB11_09510	COG0395	ABC-type sugar transport system, permease component
NicSoilB11_09520	COG1175	transmembrane transport
NicSoilB11_09540	COG3684	Belongs to the aldolase LacD family
NicSoilB11_09560	COG0673	inositol 2-dehydrogenase activity
NicSoilB11_09640	COG0477	Major facilitator Superfamily
NicSoilB11_09690	COG4209	transmembrane transport
NicSoilB11_09700	COG0395	ABC-type sugar transport system, permease component
NicSoilB11_09750	COG1472	Belongs to the glycosyl hydrolase 3 family
NicSoilB11_09760	COG0673	inositol 2-dehydrogenase activity
NicSoilB11_09790	COG1609	Transcriptional regulator
NicSoilB11_09830	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NicSoilB11_09840	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NicSoilB11_09850	COG4770	biotin carboxylase activity
NicSoilB11_10020	COG0395	ABC-type sugar transport system, permease component
NicSoilB11_10170	COG3619	membrane
NicSoilB11_10300	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NicSoilB11_10310	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
NicSoilB11_10350	COG0028	Belongs to the TPP enzyme family
NicSoilB11_10380	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NicSoilB11_10390	COG1113	amino acid transport
NicSoilB11_10450	COG1358	cellular component organization or biogenesis
NicSoilB11_10500	COG3853	Toxic anion resistance protein (TelA)
NicSoilB11_10550	COG2304	oxidoreductase activity
NicSoilB11_10590	COG1113	amino acid transport
NicSoilB11_10640	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NicSoilB11_10650	COG0531	amino acid
NicSoilB11_10660	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NicSoilB11_10720	COG2826	transposase and inactivated derivatives, IS30 family
NicSoilB11_10730	COG1201	RNA secondary structure unwinding
NicSoilB11_10830	COG1349	DNA-binding transcription factor activity
NicSoilB11_10840	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NicSoilB11_10860	COG2072	flavoprotein involved in K transport
NicSoilB11_10870	COG1063	alcohol dehydrogenase
NicSoilB11_10910	COG1609	Transcriptional regulator
NicSoilB11_10940	COG1129	ABC transporter
NicSoilB11_10950	COG1172	Belongs to the binding-protein-dependent transport system permease family
NicSoilB11_11050	COG2350	Protein conserved in bacteria
NicSoilB11_11060	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NicSoilB11_11070	COG0477	Major facilitator Superfamily
NicSoilB11_11100	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NicSoilB11_11130	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
NicSoilB11_11200	COG1349	DNA-binding transcription factor activity
NicSoilB11_11210	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NicSoilB11_11220	COG3395	kinase activity
NicSoilB11_11310	COG0456	acetyltransferase
NicSoilB11_11320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NicSoilB11_11330	COG0477	Major facilitator Superfamily
NicSoilB11_11350	COG2186	Transcriptional regulator
NicSoilB11_11400	COG3540	Alkaline phosphatase
NicSoilB11_11440	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NicSoilB11_11540	COG2072	flavoprotein involved in K transport
NicSoilB11_11570	COG1914	H( )-stimulated, divalent metal cation uptake system
NicSoilB11_11600	COG1278	Cold shock
NicSoilB11_11630	COG3265	gluconokinase activity
NicSoilB11_11640	COG2610	gluconate transmembrane transporter activity
NicSoilB11_11670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NicSoilB11_11700	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NicSoilB11_11710	COG0546	phosphoglycolate phosphatase activity
NicSoilB11_11730	COG1012	belongs to the aldehyde dehydrogenase family
NicSoilB11_11750	COG0833	amino acid
NicSoilB11_11770	COG1414	Transcriptional regulator
NicSoilB11_11800	COG2040	homocysteine
NicSoilB11_11820	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NicSoilB11_11850	COG3437	response regulator, receiver
NicSoilB11_11850	COG2205	protein histidine kinase activity
NicSoilB11_11850	COG3850	Histidine kinase
NicSoilB11_11850	COG4999	Histidine kinase
NicSoilB11_11860	COG5001	Diguanylate cyclase
NicSoilB11_11860	COG3300	MHYT domain
NicSoilB11_11880	COG0561	phosphatase activity
NicSoilB11_11890	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NicSoilB11_11900	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NicSoilB11_11900	COG0438	transferase activity, transferring glycosyl groups
NicSoilB11_11910	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
NicSoilB11_11960	COG0477	Major facilitator Superfamily
NicSoilB11_11970	COG0138	bifunctional purine biosynthesis protein purh
NicSoilB11_12000	COG2838	Isocitrate dehydrogenase
NicSoilB11_12020	COG0515	serine threonine protein kinase
NicSoilB11_12060	COG1136	(ABC) transporter
NicSoilB11_12080	COG0464	growth
NicSoilB11_12110	COG1172	Belongs to the binding-protein-dependent transport system permease family
NicSoilB11_12140	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NicSoilB11_12160	COG0531	amino acid
NicSoilB11_12200	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NicSoilB11_12210	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NicSoilB11_12220	COG1131	(ABC) transporter
NicSoilB11_12260	COG0708	Exodeoxyribonuclease III
NicSoilB11_12270	COG0180	Tryptophanyl-tRNA synthetase
NicSoilB11_12330	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NicSoilB11_12360	COG2009	succinate dehydrogenase
NicSoilB11_12380	COG1473	amidohydrolase
NicSoilB11_12380	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NicSoilB11_12390	COG1846	Transcriptional regulator
NicSoilB11_12400	COG1764	response to oxidative stress
NicSoilB11_12410	COG2130	NADP-dependent
NicSoilB11_12430	COG1744	ABC transporter substrate-binding protein PnrA-like
NicSoilB11_12440	COG3845	ABC transporter
NicSoilB11_12450	COG4603	Belongs to the binding-protein-dependent transport system permease family
NicSoilB11_12460	COG1079	Belongs to the binding-protein-dependent transport system permease family
NicSoilB11_12490	COG0586	Pfam SNARE associated Golgi protein
NicSoilB11_12500	COG0586	Pfam SNARE associated Golgi protein
NicSoilB11_12510	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NicSoilB11_12520	COG3956	TIGRFAM MazG family protein
NicSoilB11_12530	COG0148	phosphopyruvate hydratase activity
NicSoilB11_12570	COG1404	Belongs to the peptidase S8 family
NicSoilB11_12580	COG1252	NADH dehydrogenase
NicSoilB11_12660	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NicSoilB11_12680	COG2017	converts alpha-aldose to the beta-anomer
NicSoilB11_12700	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NicSoilB11_12720	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NicSoilB11_12740	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NicSoilB11_12770	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NicSoilB11_12780	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NicSoilB11_12850	COG0114	fumarate hydratase activity
NicSoilB11_12860	COG0288	reversible hydration of carbon dioxide
NicSoilB11_12880	COG1494	fructose-1,6-bisphosphatase
NicSoilB11_12900	COG1482	cell wall glycoprotein biosynthetic process
NicSoilB11_12910	COG1316	TRANSCRIPTIONal
NicSoilB11_13030	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NicSoilB11_13080	COG1022	Amp-dependent synthetase and ligase
NicSoilB11_13140	COG0714	Associated with various cellular activities
NicSoilB11_13150	COG0084	hydrolase, TatD family'
NicSoilB11_13160	COG3583	domain protein
NicSoilB11_13170	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NicSoilB11_13180	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NicSoilB11_13190	COG0488	(ABC) transporter
NicSoilB11_13210	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NicSoilB11_13230	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NicSoilB11_13240	COG0193	aminoacyl-tRNA hydrolase activity
NicSoilB11_13280	COG0822	iron-sulfur transferase activity
NicSoilB11_13310	COG0702	epimerase
NicSoilB11_13350	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NicSoilB11_13360	COG0446	pyridine nucleotide-disulphide oxidoreductase
NicSoilB11_13380	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NicSoilB11_13380	COG1648	precorrin-2 dehydrogenase activity
NicSoilB11_13390	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NicSoilB11_13410	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NicSoilB11_13490	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NicSoilB11_13500	COG0243	molybdopterin cofactor binding
NicSoilB11_13510	COG2223	nitrite transmembrane transporter activity
NicSoilB11_13520	COG0477	Major facilitator Superfamily
NicSoilB11_13550	COG4770	biotin carboxylase activity
NicSoilB11_13560	COG0424	maF-like protein
NicSoilB11_13570	COG2409	Drug exporters of the RND superfamily
NicSoilB11_13600	COG1823	symporter activity
NicSoilB11_13630	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NicSoilB11_13650	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
NicSoilB11_13650	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
NicSoilB11_13700	COG0714	Associated with various cellular activities
NicSoilB11_13750	COG0631	protein serine/threonine phosphatase activity
NicSoilB11_13790	COG1674	ftsk spoiiie
NicSoilB11_13810	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NicSoilB11_13820	COG0483	inositol monophosphate 1-phosphatase activity
NicSoilB11_13840	COG0251	oxidation-reduction process
NicSoilB11_13850	COG4565	transcriptional regulatory protein
NicSoilB11_13870	COG2851	Citrate transporter
NicSoilB11_13880	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NicSoilB11_13890	COG0154	amidase activity
NicSoilB11_13900	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NicSoilB11_13920	COG0583	DNA-binding transcription factor activity
NicSoilB11_13930	COG1063	alcohol dehydrogenase
NicSoilB11_13960	COG1228	amidohydrolase
NicSoilB11_14020	COG2873	o-acetylhomoserine
NicSoilB11_14030	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NicSoilB11_14110	COG0400	carboxylic ester hydrolase activity
NicSoilB11_14140	COG0423	glycine-tRNA ligase activity
NicSoilB11_14270	COG0358	DNA primase activity
NicSoilB11_14300	COG2814	Major facilitator Superfamily
NicSoilB11_14370	COG0052	Belongs to the universal ribosomal protein uS2 family
NicSoilB11_14380	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NicSoilB11_14390	COG0528	UMP kinase activity
NicSoilB11_14400	COG0233	cytoplasmic translational termination
NicSoilB11_14440	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NicSoilB11_14460	COG3279	Response regulator of the LytR AlgR family
NicSoilB11_14470	COG3275	phosphorelay sensor kinase activity
NicSoilB11_14490	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NicSoilB11_14530	COG1522	sequence-specific DNA binding
NicSoilB11_14550	COG0022	dehydrogenase e1 component
NicSoilB11_14560	COG0508	dehydrogenase complex catalyzes the overall conversion of
NicSoilB11_14580	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NicSoilB11_14600	COG1960	acyl-CoA dehydrogenase activity
NicSoilB11_14660	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NicSoilB11_14670	COG0750	zinc metalloprotease
NicSoilB11_14710	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NicSoilB11_14740	COG1309	transcriptional regulator
NicSoilB11_14780	COG0442	prolyl-tRNA aminoacylation
NicSoilB11_14810	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
NicSoilB11_14840	COG0779	Required for maturation of 30S ribosomal subunits
NicSoilB11_14850	COG0195	Participates in both transcription termination and antitermination
NicSoilB11_14870	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NicSoilB11_14890	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NicSoilB11_14910	COG0590	tRNA wobble adenosine to inosine editing
NicSoilB11_14930	COG0436	Aminotransferase
NicSoilB11_14940	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NicSoilB11_14980	COG3483	tryptophan 2,3-dioxygenase activity
NicSoilB11_15000	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NicSoilB11_15010	COG1185	polyribonucleotide nucleotidyltransferase activity
NicSoilB11_15020	COG0612	Peptidase, M16
NicSoilB11_15120	COG0521	Mo-molybdopterin cofactor biosynthetic process
NicSoilB11_15140	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NicSoilB11_15190	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NicSoilB11_15200	COG1674	ftsk spoiiie
NicSoilB11_15220	COG1546	Belongs to the CinA family
NicSoilB11_15220	COG1058	Belongs to the CinA family
NicSoilB11_15240	COG1396	sequence-specific DNA binding
NicSoilB11_15270	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NicSoilB11_15280	COG2137	regulation of response to DNA damage stimulus
NicSoilB11_15290	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NicSoilB11_15300	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NicSoilB11_15310	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NicSoilB11_15320	COG2813	Specifically methylates the guanine in position
NicSoilB11_15330	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NicSoilB11_15350	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NicSoilB11_15370	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NicSoilB11_15380	COG0131	Imidazoleglycerol-phosphate dehydratase
NicSoilB11_15390	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NicSoilB11_15410	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NicSoilB11_15450	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NicSoilB11_15460	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NicSoilB11_15470	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NicSoilB11_15500	COG2814	Major facilitator Superfamily
NicSoilB11_15520	COG0494	nUDIX hydrolase
NicSoilB11_15560	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NicSoilB11_15570	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NicSoilB11_15570	COG0072	phenylalanine-tRNA ligase activity
NicSoilB11_15590	COG2801	Transposase and inactivated derivatives
NicSoilB11_15610	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NicSoilB11_15620	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NicSoilB11_15630	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NicSoilB11_15640	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NicSoilB11_15650	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NicSoilB11_15660	COG1438	arginine binding
NicSoilB11_15670	COG0137	argininosuccinate synthase activity
NicSoilB11_15680	COG0165	Argininosuccinate lyase
NicSoilB11_15690	COG0259	pyridoxamine-phosphate oxidase activity
NicSoilB11_15730	COG2094	Belongs to the DNA glycosylase MPG family
NicSoilB11_15740	COG3973	AAA domain
NicSoilB11_15750	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NicSoilB11_15770	COG0647	UMP catabolic process
NicSoilB11_15800	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NicSoilB11_15810	COG0497	DNA recombination
NicSoilB11_15820	COG0504	CTP synthase activity
NicSoilB11_15830	COG0494	nUDIX hydrolase
NicSoilB11_15880	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NicSoilB11_15890	COG2079	MmgE PrpD family protein
NicSoilB11_15930	COG3290	protein histidine kinase activity
NicSoilB11_15940	COG1301	dicarboxylic acid transport
NicSoilB11_15960	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NicSoilB11_15970	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NicSoilB11_16000	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NicSoilB11_16020	COG1160	GTP binding
NicSoilB11_16040	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NicSoilB11_16050	COG0509	glycine decarboxylation via glycine cleavage system
NicSoilB11_16060	COG1716	ATPase activity
NicSoilB11_16100	COG1192	Involved in chromosome partitioning
NicSoilB11_16110	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NicSoilB11_16130	COG1940	carbohydrate kinase activity
NicSoilB11_16180	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
NicSoilB11_16190	COG0515	serine threonine protein kinase
NicSoilB11_16190	COG2815	serine threonine protein kinase
NicSoilB11_16200	COG1388	LysM domain
NicSoilB11_16200	COG3942	CHAP domain
NicSoilB11_16220	COG0142	geranyltranstransferase activity
NicSoilB11_16240	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NicSoilB11_16260	COG2001	Belongs to the MraZ family
NicSoilB11_16270	COG0275	rRNA processing
NicSoilB11_16290	COG0768	penicillin binding
NicSoilB11_16300	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NicSoilB11_16320	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NicSoilB11_16330	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NicSoilB11_16340	COG0772	Belongs to the SEDS family
NicSoilB11_16350	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NicSoilB11_16360	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NicSoilB11_16370	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NicSoilB11_16380	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NicSoilB11_16390	COG1496	oxidoreductase activity
NicSoilB11_16400	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NicSoilB11_16410	COG1799	cell septum assembly
NicSoilB11_16430	COG3599	regulation of cell shape
NicSoilB11_16440	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NicSoilB11_16460	COG0587	DNA-directed DNA polymerase activity
NicSoilB11_16490	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NicSoilB11_16500	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NicSoilB11_16540	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NicSoilB11_16550	COG0174	glutamine synthetase
NicSoilB11_16560	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
NicSoilB11_16630	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NicSoilB11_16640	COG0321	lipoyl(octanoyl) transferase activity
NicSoilB11_16660	COG1090	epimerase
NicSoilB11_16670	COG4946	Tricorn protease homolog
NicSoilB11_16670	COG0793	Belongs to the peptidase S41A family
NicSoilB11_16680	COG2801	Transposase and inactivated derivatives
NicSoilB11_16680	COG3415	Transposase
NicSoilB11_16690	COG1764	response to oxidative stress
NicSoilB11_16710	COG0508	dehydrogenase complex catalyzes the overall conversion of
NicSoilB11_16720	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NicSoilB11_16730	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NicSoilB11_16770	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NicSoilB11_16820	COG1271	oxidase subunit
NicSoilB11_16830	COG1294	oxidase, subunit
NicSoilB11_16840	COG4988	ABC transporter
NicSoilB11_16860	COG1131	(ABC) transporter
NicSoilB11_16880	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NicSoilB11_16920	COG1435	thymidine kinase activity
NicSoilB11_16970	COG0756	dUTP diphosphatase activity
NicSoilB11_17020	COG0569	domain protein
NicSoilB11_17030	COG0531	amino acid
NicSoilB11_17040	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NicSoilB11_17050	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NicSoilB11_17060	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NicSoilB11_17090	COG0667	Aldo Keto reductase
NicSoilB11_17130	COG1122	ATPase activity
NicSoilB11_17140	COG1250	3-hydroxyacyl-CoA dehydrogenase
NicSoilB11_17140	COG1024	Enoyl-CoA hydratase
NicSoilB11_17150	COG0183	Belongs to the thiolase family
NicSoilB11_17160	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
NicSoilB11_17210	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NicSoilB11_17240	COG1012	belongs to the aldehyde dehydrogenase family
NicSoilB11_17260	COG2132	Multicopper oxidase
NicSoilB11_17270	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NicSoilB11_17310	COG3135	benzoate transporter
NicSoilB11_17340	COG0242	peptide deformylase activity
NicSoilB11_17350	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NicSoilB11_17370	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NicSoilB11_17400	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NicSoilB11_17400	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NicSoilB11_17420	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NicSoilB11_17430	COG0140	phosphoribosyl-ATP diphosphatase activity
NicSoilB11_17440	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NicSoilB11_17450	COG0107	imidazoleglycerol-phosphate synthase activity
NicSoilB11_17470	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NicSoilB11_17500	COG0134	indole-3-glycerol-phosphate synthase activity
NicSoilB11_17510	COG0133	tryptophan synthase activity
NicSoilB11_17520	COG0159	tryptophan synthase activity
NicSoilB11_17530	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NicSoilB11_17540	COG0069	glutamate synthase activity
NicSoilB11_17540	COG0070	glutamate synthase
NicSoilB11_17540	COG0067	glutamate synthase
NicSoilB11_17750	COG5001	Diguanylate cyclase
NicSoilB11_17830	COG0784	Response regulator, receiver
NicSoilB11_17830	COG2205	protein histidine kinase activity
NicSoilB11_17830	COG5002	protein histidine kinase activity
NicSoilB11_17970	COG1733	regulation of RNA biosynthetic process
NicSoilB11_18150	COG0800	Aldolase
NicSoilB11_18170	COG1609	Transcriptional regulator
NicSoilB11_18240	COG0395	ABC-type sugar transport system, permease component
NicSoilB11_18290	COG2154	pterin-4-alpha-carbinolamine dehydratase
NicSoilB11_18320	COG2135	peptidase activity
NicSoilB11_18330	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NicSoilB11_18400	COG1063	alcohol dehydrogenase
NicSoilB11_18420	COG4638	Rieske (2fe-2S)
NicSoilB11_18450	COG0437	4 iron, 4 sulfur cluster binding
NicSoilB11_18470	COG0709	Synthesizes selenophosphate from selenide and ATP
NicSoilB11_18520	COG1082	Xylose isomerase domain protein TIM barrel
NicSoilB11_18540	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NicSoilB11_18590	COG2124	cytochrome p450
NicSoilB11_18600	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NicSoilB11_18600	COG2755	lipolytic protein G-D-S-L family
NicSoilB11_18640	COG0667	Aldo Keto reductase
NicSoilB11_18660	COG2268	Band 7 protein
NicSoilB11_18680	COG1028	Short-chain dehydrogenase reductase Sdr
NicSoilB11_18710	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NicSoilB11_18740	COG0406	alpha-ribazole phosphatase activity
NicSoilB11_18750	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
NicSoilB11_18780	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NicSoilB11_18790	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NicSoilB11_18820	COG1643	Atp-dependent helicase
NicSoilB11_18860	COG0009	L-threonylcarbamoyladenylate synthase
NicSoilB11_18920	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NicSoilB11_18930	COG2050	protein possibly involved in aromatic compounds catabolism
NicSoilB11_18950	COG4552	Acetyltransferase involved in intracellular survival and related
NicSoilB11_18960	COG0539	negative regulation of cytoplasmic translation
NicSoilB11_18980	COG1739	Uncharacterized protein family UPF0029
NicSoilB11_18990	COG0237	dephospho-CoA kinase activity
NicSoilB11_18990	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NicSoilB11_19000	COG0556	nucleotide-excision repair
NicSoilB11_19010	COG1653	transport
NicSoilB11_19030	COG0477	Major facilitator Superfamily
NicSoilB11_19070	COG4106	trans-aconitate 2-methyltransferase activity
NicSoilB11_19120	COG0546	phosphoglycolate phosphatase activity
NicSoilB11_19130	COG0318	PFAM AMP-dependent synthetase and ligase
NicSoilB11_19130	COG0204	Acyl-transferase
NicSoilB11_19140	COG0322	excinuclease ABC activity
NicSoilB11_19150	COG1660	Displays ATPase and GTPase activities
NicSoilB11_19160	COG0391	Required for morphogenesis under gluconeogenic growth conditions
NicSoilB11_19170	COG1481	regulation of sporulation
NicSoilB11_19180	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NicSoilB11_19190	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NicSoilB11_19200	COG0126	phosphoglycerate kinase activity
NicSoilB11_19210	COG0149	triose-phosphate isomerase activity
NicSoilB11_19220	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NicSoilB11_19240	COG0363	glucosamine-6-phosphate deaminase activity
NicSoilB11_19270	COG0166	Belongs to the GPI family
NicSoilB11_19280	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NicSoilB11_19300	COG0109	protoheme IX farnesyltransferase activity
NicSoilB11_19310	COG0659	secondary active sulfate transmembrane transporter activity
NicSoilB11_19320	COG1612	heme a metabolic process
NicSoilB11_19340	COG1131	(ABC) transporter
NicSoilB11_19390	COG0396	ATPase activity
NicSoilB11_19400	COG2151	metal-sulfur cluster biosynthetic enzyme
NicSoilB11_19420	COG0318	PFAM AMP-dependent synthetase and ligase
NicSoilB11_19440	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NicSoilB11_19450	COG1122	ATPase activity
NicSoilB11_19460	COG1268	BioY protein
NicSoilB11_19490	COG2826	transposase and inactivated derivatives, IS30 family
NicSoilB11_19510	COG0456	acetyltransferase
NicSoilB11_19510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NicSoilB11_19520	COG2329	Antibiotic biosynthesis monooxygenase
NicSoilB11_19530	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NicSoilB11_19550	COG0346	lactoylglutathione lyase activity
NicSoilB11_19560	COG2354	Protein conserved in bacteria
NicSoilB11_19580	COG0488	(ABC) transporter
NicSoilB11_19630	COG1028	Short-chain dehydrogenase reductase Sdr
NicSoilB11_19640	COG1028	Short-chain dehydrogenase reductase Sdr
NicSoilB11_19650	COG0560	Phosphoserine phosphatase
NicSoilB11_19650	COG3830	Belongs to the UPF0237 family
NicSoilB11_19670	COG1119	ATPase activity
NicSoilB11_19700	COG0254	rRNA binding
NicSoilB11_19730	COG2855	membrane
NicSoilB11_19760	COG1305	Transglutaminase-like
NicSoilB11_19790	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NicSoilB11_19800	COG0297	glycogen (starch) synthase activity
NicSoilB11_19840	COG1028	Short-chain dehydrogenase reductase Sdr
NicSoilB11_19880	COG0435	Glutathione S-transferase
NicSoilB11_19950	COG1063	alcohol dehydrogenase
NicSoilB11_19980	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NicSoilB11_20020	COG0667	Aldo Keto reductase
NicSoilB11_20040	COG1968	undecaprenyl-diphosphatase activity
NicSoilB11_20050	COG0215	cysteine-tRNA ligase activity
NicSoilB11_20070	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NicSoilB11_20080	COG0517	IMP dehydrogenase activity
NicSoilB11_20080	COG1994	Peptidase M50
NicSoilB11_20100	COG1222	aaa ATPase
NicSoilB11_20110	COG4122	O-methyltransferase activity
NicSoilB11_20130	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NicSoilB11_20140	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NicSoilB11_20150	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NicSoilB11_20160	COG0545	Peptidyl-prolyl cis-trans isomerase
NicSoilB11_20200	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NicSoilB11_20210	COG0805	protein transport
NicSoilB11_20220	COG4581	dead DEAH box helicase
NicSoilB11_20230	COG1574	metal-dependent hydrolase with the TIM-barrel fold
NicSoilB11_20240	COG1216	Glycosyl transferase, family 2
NicSoilB11_20290	COG0242	peptide deformylase activity
NicSoilB11_20320	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NicSoilB11_20330	COG3424	synthase
NicSoilB11_20340	COG1404	Belongs to the peptidase S8 family
NicSoilB11_20380	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NicSoilB11_20390	COG1845	cytochrome c oxidase, subunit III
NicSoilB11_20400	COG2010	Cytochrome c
NicSoilB11_20410	COG0723	plastoquinol--plastocyanin reductase activity
NicSoilB11_20420	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NicSoilB11_20460	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NicSoilB11_20470	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NicSoilB11_20510	COG0167	dihydroorotate dehydrogenase activity
NicSoilB11_20530	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NicSoilB11_20540	COG1381	Involved in DNA repair and RecF pathway recombination
NicSoilB11_20550	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NicSoilB11_20560	COG3590	peptidase
NicSoilB11_20570	COG1316	TRANSCRIPTIONal
NicSoilB11_20580	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NicSoilB11_20600	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NicSoilB11_20630	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NicSoilB11_20640	COG0484	heat shock protein binding
NicSoilB11_20650	COG1420	regulation of RNA biosynthetic process
NicSoilB11_20690	COG0481	GTPase activity
NicSoilB11_20710	COG0268	Binds directly to 16S ribosomal RNA
NicSoilB11_20750	COG1307	EDD domain protein, DegV family
NicSoilB11_20760	COG0495	leucyl-tRNA aminoacylation
NicSoilB11_20810	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NicSoilB11_20820	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NicSoilB11_20850	COG2390	Transcriptional regulator
NicSoilB11_20860	COG0656	L-ascorbic acid biosynthetic process
NicSoilB11_20880	COG0438	transferase activity, transferring glycosyl groups
NicSoilB11_20900	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NicSoilB11_20920	COG1758	RNA polymerase activity
NicSoilB11_20930	COG0194	GDP metabolic process
NicSoilB11_20940	COG0194	GDP metabolic process
NicSoilB11_20950	COG0284	orotidine-5'-phosphate decarboxylase activity
NicSoilB11_20960	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NicSoilB11_20970	COG0505	Belongs to the CarA family
NicSoilB11_20990	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NicSoilB11_21000	COG0540	Belongs to the ATCase OTCase family
NicSoilB11_21010	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NicSoilB11_21030	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NicSoilB11_21040	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NicSoilB11_21060	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NicSoilB11_21070	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NicSoilB11_21080	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NicSoilB11_21090	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NicSoilB11_21120	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NicSoilB11_21150	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NicSoilB11_21190	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NicSoilB11_21210	COG0124	histidyl-tRNA synthetase
NicSoilB11_21230	COG1196	nuclear chromosome segregation
NicSoilB11_21250	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NicSoilB11_21260	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NicSoilB11_21270	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NicSoilB11_21290	COG2255	four-way junction helicase activity
NicSoilB11_21300	COG0632	four-way junction helicase activity
NicSoilB11_21310	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NicSoilB11_21320	COG0217	transcriptional regulatory protein
NicSoilB11_21330	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NicSoilB11_21340	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NicSoilB11_21360	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NicSoilB11_21380	COG0339	signal peptide processing
NicSoilB11_21390	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NicSoilB11_21400	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NicSoilB11_21420	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NicSoilB11_21430	COG0587	DNA-directed DNA polymerase activity
NicSoilB11_21460	COG0077	Prephenate dehydratase
NicSoilB11_21460	COG1605	Chorismate mutase
NicSoilB11_21480	COG2135	peptidase activity
NicSoilB11_21510	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NicSoilB11_21520	COG1695	Transcriptional regulator
NicSoilB11_21590	COG1028	Short-chain dehydrogenase reductase Sdr
NicSoilB11_21650	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
NicSoilB11_21660	COG1234	tRNA 3'-trailer cleavage
NicSoilB11_21690	COG0589	response to stress
NicSoilB11_21830	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NicSoilB11_21850	COG0574	Belongs to the PEP-utilizing enzyme family
NicSoilB11_21850	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NicSoilB11_21860	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NicSoilB11_21880	COG2217	Heavy metal translocating P-type atpase
NicSoilB11_22090	COG1842	Phage shock protein A
NicSoilB11_22110	COG4152	abc transporter atp-binding protein
NicSoilB11_22150	COG1175	transmembrane transport
NicSoilB11_22160	COG0395	ABC-type sugar transport system, permease component
NicSoilB11_22170	COG4948	Mandelate Racemase Muconate Lactonizing
NicSoilB11_22200	COG0492	ferredoxin-NADP+ reductase activity
NicSoilB11_22640	COG2801	Transposase and inactivated derivatives
NicSoilB11_22650	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NicSoilB11_22660	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NicSoilB11_22670	COG1780	Probably involved in ribonucleotide reductase function
NicSoilB11_22700	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NicSoilB11_22730	COG0583	DNA-binding transcription factor activity
NicSoilB11_22760	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NicSoilB11_22830	COG0714	Associated with various cellular activities
NicSoilB11_22860	COG1175	transmembrane transport
NicSoilB11_22890	COG2813	Specifically methylates the guanine in position
NicSoilB11_22900	COG0492	ferredoxin-NADP+ reductase activity
NicSoilB11_22910	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NicSoilB11_22940	COG0799	negative regulation of ribosome biogenesis
NicSoilB11_22960	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NicSoilB11_22980	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NicSoilB11_22990	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NicSoilB11_23000	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NicSoilB11_23010	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NicSoilB11_23020	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NicSoilB11_23030	COG0351	phosphomethylpyrimidine kinase
NicSoilB11_23030	COG0352	thiamine-phosphate diphosphorylase activity
NicSoilB11_23030	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NicSoilB11_23040	COG1530	ribonuclease E activity
NicSoilB11_23060	COG0105	UTP biosynthetic process
NicSoilB11_23080	COG0285	dihydrofolate synthase activity
NicSoilB11_23090	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NicSoilB11_23130	COG3189	MarR family transcriptional regulator
NicSoilB11_23140	COG0525	valine-tRNA ligase activity
NicSoilB11_23150	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NicSoilB11_23160	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NicSoilB11_23170	COG0740	serine-type endopeptidase activity
NicSoilB11_23180	COG0740	serine-type endopeptidase activity
NicSoilB11_23190	COG0544	peptidyl-prolyl cis-trans isomerase activity
NicSoilB11_23260	COG0668	transmembrane transport
NicSoilB11_23270	COG2346	COG2346, Truncated hemoglobins
NicSoilB11_23290	COG1946	Acyl-CoA thioesterase
NicSoilB11_23320	COG0629	single-stranded DNA binding
NicSoilB11_23340	COG2115	Belongs to the xylose isomerase family
NicSoilB11_23350	COG1070	Carbohydrate kinase
NicSoilB11_23360	COG1082	Xylose isomerase domain protein TIM barrel
NicSoilB11_23380	COG0673	inositol 2-dehydrogenase activity
NicSoilB11_23390	COG1609	Transcriptional regulator
NicSoilB11_23400	COG0657	acetylesterase activity
NicSoilB11_23400	COG2755	lipolytic protein G-D-S-L family
NicSoilB11_23410	COG2017	converts alpha-aldose to the beta-anomer
NicSoilB11_23440	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NicSoilB11_23450	COG0242	peptide deformylase activity
NicSoilB11_23500	COG3022	response to hydroperoxide
NicSoilB11_23520	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NicSoilB11_23530	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NicSoilB11_23550	COG1045	serine acetyltransferase
NicSoilB11_23560	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NicSoilB11_23580	COG1063	alcohol dehydrogenase
NicSoilB11_23590	COG1028	Short-chain dehydrogenase reductase Sdr
NicSoilB11_23600	COG2084	Dehydrogenase
NicSoilB11_23650	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
NicSoilB11_23680	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NicSoilB11_23690	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NicSoilB11_23700	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NicSoilB11_23720	COG4974	Belongs to the 'phage' integrase family
NicSoilB11_23750	COG0792	nuclease activity
NicSoilB11_23770	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NicSoilB11_23790	COG0681	Belongs to the peptidase S26 family
NicSoilB11_23800	COG0335	large ribosomal subunit rRNA binding
NicSoilB11_23810	COG0336	Belongs to the RNA methyltransferase TrmD family
NicSoilB11_23820	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NicSoilB11_23830	COG1837	Belongs to the UPF0109 family
NicSoilB11_23840	COG0228	four-way junction DNA binding
NicSoilB11_23860	COG2514	catechol 2,3-dioxygenase activity
NicSoilB11_23910	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NicSoilB11_23970	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NicSoilB11_23980	COG0318	PFAM AMP-dependent synthetase and ligase
NicSoilB11_23990	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NicSoilB11_24000	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NicSoilB11_24010	COG0571	ribonuclease III activity
NicSoilB11_24020	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NicSoilB11_24040	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NicSoilB11_24070	COG0742	ribosomal rna small subunit methyltransferase
NicSoilB11_24080	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NicSoilB11_24090	COG1461	Dihydroxyacetone kinase
NicSoilB11_24120	COG1181	Belongs to the D-alanine--D-alanine ligase family
NicSoilB11_24130	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NicSoilB11_24150	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NicSoilB11_24160	COG0066	3-isopropylmalate dehydratase activity
NicSoilB11_24170	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NicSoilB11_24180	COG1414	Transcriptional regulator
NicSoilB11_24210	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NicSoilB11_24240	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NicSoilB11_24250	COG0179	Fumarylacetoacetate (FAA) hydrolase
NicSoilB11_24260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NicSoilB11_24270	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NicSoilB11_24280	COG0473	3-isopropylmalate dehydrogenase activity
NicSoilB11_24290	COG4585	Histidine kinase
NicSoilB11_24300	COG2197	response regulator
NicSoilB11_24310	COG0577	efflux transmembrane transporter activity
NicSoilB11_24310	COG1136	(ABC) transporter
NicSoilB11_24340	COG0577	efflux transmembrane transporter activity
NicSoilB11_24340	COG1136	(ABC) transporter
NicSoilB11_24360	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NicSoilB11_24370	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NicSoilB11_24380	COG0440	acetolactate synthase activity
NicSoilB11_24400	COG0129	dihydroxy-acid dehydratase activity
NicSoilB11_24410	COG0088	Forms part of the polypeptide exit tunnel
NicSoilB11_24460	COG0747	negative chemotaxis
NicSoilB11_24470	COG0579	oxidoreductase
NicSoilB11_24480	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NicSoilB11_24490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NicSoilB11_24510	COG1305	Transglutaminase-like
NicSoilB11_24550	COG1104	cysteine desulfurase activity
NicSoilB11_24570	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NicSoilB11_24580	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NicSoilB11_24610	COG1113	amino acid transport
NicSoilB11_24640	COG0477	Major facilitator Superfamily
NicSoilB11_24670	COG0419	ATPase involved in DNA repair
NicSoilB11_24680	COG0420	3'-5' exonuclease activity
NicSoilB11_24730	COG0586	Pfam SNARE associated Golgi protein
NicSoilB11_24740	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NicSoilB11_24750	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NicSoilB11_24760	COG1234	tRNA 3'-trailer cleavage
NicSoilB11_24770	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NicSoilB11_24790	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NicSoilB11_24810	COG1335	isochorismatase
NicSoilB11_24840	COG0363	glucosamine-6-phosphate deaminase activity
NicSoilB11_24900	COG1902	pentaerythritol trinitrate reductase activity
NicSoilB11_24930	COG0628	permease
NicSoilB11_24960	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
NicSoilB11_24980	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NicSoilB11_24990	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
NicSoilB11_25010	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NicSoilB11_25020	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NicSoilB11_25030	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NicSoilB11_25040	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NicSoilB11_25050	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NicSoilB11_25060	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NicSoilB11_25070	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NicSoilB11_25080	COG0356	it plays a direct role in the translocation of protons across the membrane
NicSoilB11_25150	COG2890	protein-(glutamine-N5) methyltransferase activity
NicSoilB11_25160	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NicSoilB11_25180	COG0083	homoserine kinase activity
NicSoilB11_25190	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NicSoilB11_25200	COG0460	homoserine dehydrogenase
NicSoilB11_25210	COG0019	diaminopimelate decarboxylase activity
NicSoilB11_25220	COG0018	arginyl-trna synthetase
NicSoilB11_25260	COG1017	nitric oxide dioxygenase activity
NicSoilB11_25260	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NicSoilB11_25320	COG1643	Atp-dependent helicase
NicSoilB11_25330	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NicSoilB11_25340	COG0537	adenosine 5'-monophosphoramidase activity
NicSoilB11_25350	COG1064	alcohol dehydrogenase
NicSoilB11_25370	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NicSoilB11_25380	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NicSoilB11_25410	COG3842	ATPase activity
NicSoilB11_25420	COG0803	Belongs to the bacterial solute-binding protein 9 family
NicSoilB11_25450	COG0508	dehydrogenase complex catalyzes the overall conversion of
NicSoilB11_25450	COG0567	Dehydrogenase, E1 component
NicSoilB11_25500	COG1595	DNA-templated transcription, initiation
NicSoilB11_25530	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NicSoilB11_25550	COG0483	inositol monophosphate 1-phosphatase activity
NicSoilB11_25560	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NicSoilB11_25590	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NicSoilB11_25600	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NicSoilB11_25620	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NicSoilB11_25640	COG1063	alcohol dehydrogenase
NicSoilB11_25710	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NicSoilB11_25740	COG2884	Cell division ATP-binding protein ftsE
NicSoilB11_25750	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NicSoilB11_25990	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NicSoilB11_26000	COG1088	dTDP-glucose 4,6-dehydratase activity
NicSoilB11_26120	COG2826	transposase and inactivated derivatives, IS30 family
NicSoilB11_26170	COG1216	Glycosyl transferase, family 2
NicSoilB11_26230	COG2902	Dehydrogenase
NicSoilB11_26240	COG0489	protein tyrosine kinase activity
NicSoilB11_26300	COG0653	protein targeting
NicSoilB11_26310	COG3214	Protein conserved in bacteria
NicSoilB11_26320	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NicSoilB11_26350	COG5401	PFAM Sporulation and spore germination
NicSoilB11_26360	COG5002	protein histidine kinase activity
NicSoilB11_26410	COG0714	Associated with various cellular activities
NicSoilB11_26470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NicSoilB11_26480	COG0601	transmembrane transport
NicSoilB11_26490	COG4533	DNA binding
NicSoilB11_26490	COG4533	DNA binding
NicSoilB11_26500	COG0482	sulfurtransferase activity
NicSoilB11_26550	COG0484	heat shock protein binding
NicSoilB11_26560	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NicSoilB11_26600	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
NicSoilB11_26610	COG2086	electron transfer activity
NicSoilB11_26620	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NicSoilB11_26640	COG1842	Phage shock protein A
NicSoilB11_26650	COG0415	Belongs to the DNA photolyase family
NicSoilB11_26670	COG1615	UPF0182 protein
NicSoilB11_26680	COG3480	Lon protease (S16) C-terminal proteolytic domain
NicSoilB11_26720	COG2816	NAD+ diphosphatase activity
NicSoilB11_26790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NicSoilB11_26800	COG0765	amino acid transport
NicSoilB11_26810	COG1126	abc transporter atp-binding protein
NicSoilB11_26820	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NicSoilB11_26840	COG0113	porphobilinogen synthase activity
NicSoilB11_26860	COG0181	hydroxymethylbilane synthase activity
NicSoilB11_26870	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NicSoilB11_26880	COG3253	May function as heme-dependent peroxidase
NicSoilB11_26900	COG1231	oxidoreductase activity
NicSoilB11_26910	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NicSoilB11_26920	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NicSoilB11_26970	COG2022	thiamine diphosphate biosynthetic process
NicSoilB11_26990	COG2022	thiamine diphosphate biosynthetic process
NicSoilB11_26990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NicSoilB11_27000	COG0352	thiamine-phosphate diphosphorylase activity
NicSoilB11_27020	COG0513	Belongs to the DEAD box helicase family
NicSoilB11_27030	COG2189	Belongs to the N(4) N(6)-methyltransferase family
NicSoilB11_27040	COG3547	Transposase (IS116 IS110 IS902 family)
NicSoilB11_27050	COG0613	PHP domain protein
NicSoilB11_27060	COG0006	proline dipeptidase activity
NicSoilB11_27080	COG2239	Acts as a magnesium transporter
NicSoilB11_27110	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NicSoilB11_27130	COG1595	DNA-templated transcription, initiation
NicSoilB11_27140	COG4122	O-methyltransferase activity
NicSoilB11_27170	COG3599	regulation of cell shape
NicSoilB11_27190	COG1126	abc transporter atp-binding protein
NicSoilB11_27200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NicSoilB11_27210	COG0765	amino acid transport
NicSoilB11_27220	COG0765	amino acid transport
NicSoilB11_27230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NicSoilB11_27240	COG2171	N-acyltransferase activity
NicSoilB11_27270	COG3226	Transcriptional regulator
NicSoilB11_27280	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NicSoilB11_27340	COG1217	gtp-binding protein TYPA
NicSoilB11_27370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NicSoilB11_27390	COG4166	transmembrane transport
NicSoilB11_27410	COG0012	GTP binding
NicSoilB11_27420	COG1322	Protein conserved in bacteria
NicSoilB11_27430	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NicSoilB11_27450	COG1570	exodeoxyribonuclease VII activity
NicSoilB11_27460	COG1722	exodeoxyribonuclease VII activity
NicSoilB11_27470	COG2326	polyphosphate kinase activity
NicSoilB11_27500	COG1174	glycine betaine transport
NicSoilB11_27510	COG1174	glycine betaine transport
NicSoilB11_27540	COG2971	BadF BadG BcrA BcrD
NicSoilB11_27550	COG0583	DNA-binding transcription factor activity
NicSoilB11_27560	COG2814	Major facilitator Superfamily
NicSoilB11_27600	COG0598	Magnesium transport protein CorA
NicSoilB11_27670	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NicSoilB11_27680	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NicSoilB11_27720	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NicSoilB11_27720	COG0519	Catalyzes the synthesis of GMP from XMP
NicSoilB11_27760	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NicSoilB11_27770	COG0516	GMP reductase activity
NicSoilB11_27800	COG1621	beta-fructofuranosidase activity
NicSoilB11_27880	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NicSoilB11_27880	COG2755	lipolytic protein G-D-S-L family
NicSoilB11_27910	COG1793	dna ligase
NicSoilB11_27930	COG0459	protein refolding
NicSoilB11_27940	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NicSoilB11_27970	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NicSoilB11_27980	COG1472	Belongs to the glycosyl hydrolase 3 family
NicSoilB11_27990	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NicSoilB11_28000	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NicSoilB11_28010	COG1214	PFAM Peptidase M22, glycoprotease
NicSoilB11_28010	COG0456	acetyltransferase
NicSoilB11_28030	COG0802	atpase or kinase
NicSoilB11_28040	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NicSoilB11_28050	COG1105	Belongs to the carbohydrate kinase PfkB family
NicSoilB11_28070	COG0438	transferase activity, transferring glycosyl groups
NicSoilB11_28080	COG2759	Belongs to the formate--tetrahydrofolate ligase family
NicSoilB11_28110	COG0667	Aldo Keto reductase
NicSoilB11_28160	COG0736	holo-[acyl-carrier-protein] synthase activity
NicSoilB11_28170	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NicSoilB11_28180	COG1072	(Pantothenic acid kinase))
NicSoilB11_28190	COG1876	peptidase activity
NicSoilB11_28200	COG1970	mechanosensitive ion channel activity
NicSoilB11_28210	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NicSoilB11_28240	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NicSoilB11_28250	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NicSoilB11_28260	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NicSoilB11_28270	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NicSoilB11_28340	COG2894	cell division
NicSoilB11_28410	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NicSoilB11_28470	COG2894	cell division
NicSoilB11_28520	COG0745	RESPONSE REGULATOR receiver
NicSoilB11_28540	COG0101	tRNA pseudouridine synthase activity
NicSoilB11_28550	COG0203	ribosomal protein L17
NicSoilB11_28560	COG0202	RNA polymerase activity
NicSoilB11_28570	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NicSoilB11_28580	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NicSoilB11_28590	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NicSoilB11_28600	COG3191	aminopeptidase activity
NicSoilB11_28650	COG0563	adenylate kinase activity
NicSoilB11_28670	COG0200	Binds to the 23S rRNA
NicSoilB11_28680	COG1841	ribosomal large subunit assembly
NicSoilB11_28690	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NicSoilB11_28700	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NicSoilB11_28710	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NicSoilB11_28720	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NicSoilB11_28730	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NicSoilB11_28740	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NicSoilB11_28750	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NicSoilB11_28760	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NicSoilB11_28770	COG0255	Belongs to the universal ribosomal protein uL29 family
NicSoilB11_28780	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NicSoilB11_28790	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NicSoilB11_28800	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NicSoilB11_28810	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NicSoilB11_28820	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NicSoilB11_28830	COG0089	rRNA binding
NicSoilB11_28840	COG0088	Forms part of the polypeptide exit tunnel
NicSoilB11_28850	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NicSoilB11_28860	COG0051	transcription antitermination factor activity, RNA binding
NicSoilB11_28900	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NicSoilB11_28910	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NicSoilB11_28920	COG0049	tRNA binding
NicSoilB11_28930	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NicSoilB11_28940	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NicSoilB11_28950	COG0085	RNA polymerase activity
NicSoilB11_28980	COG0183	Belongs to the thiolase family
NicSoilB11_28990	COG0442	prolyl-tRNA aminoacylation
NicSoilB11_29000	COG0222	ribosome binding
NicSoilB11_29010	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NicSoilB11_29040	COG0081	regulation of translation
NicSoilB11_29050	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NicSoilB11_29080	COG0436	Aminotransferase
NicSoilB11_29090	COG2197	response regulator
NicSoilB11_29180	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NicSoilB11_29200	COG3485	protocatechuate 3,4-dioxygenase
NicSoilB11_29230	COG0745	RESPONSE REGULATOR receiver
NicSoilB11_29240	COG0456	acetyltransferase
NicSoilB11_29250	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NicSoilB11_29270	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NicSoilB11_29280	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NicSoilB11_29350	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NicSoilB11_29380	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NicSoilB11_29390	COG0738	Major facilitator superfamily
NicSoilB11_29410	COG2030	dehydratase
NicSoilB11_29450	COG4989	oxidoreductase activity
NicSoilB11_29460	COG0366	Alpha amylase catalytic
NicSoilB11_29470	COG1940	carbohydrate kinase activity
NicSoilB11_29480	COG0702	epimerase
NicSoilB11_29500	COG1140	nitrate reductase beta subunit
NicSoilB11_29550	COG0706	membrane insertase activity
NicSoilB11_29590	COG0754	glutathionylspermidine amidase activity
NicSoilB11_29670	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NicSoilB11_29750	COG0318	PFAM AMP-dependent synthetase and ligase
NicSoilB11_29770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NicSoilB11_29790	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NicSoilB11_29830	COG1666	GTP binding
NicSoilB11_29840	COG0672	)-iron permease
NicSoilB11_29860	COG2837	iron assimilation
NicSoilB11_29870	COG0501	Belongs to the peptidase M48B family
NicSoilB11_29920	COG0531	amino acid
NicSoilB11_30040	COG1012	belongs to the aldehyde dehydrogenase family
NicSoilB11_30050	COG3835	regulator
NicSoilB11_30080	COG2186	Transcriptional regulator
NicSoilB11_30150	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NicSoilB11_30150	COG1648	precorrin-2 dehydrogenase activity
NicSoilB11_30180	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NicSoilB11_30200	COG1690	Belongs to the RtcB family
NicSoilB11_30210	COG2895	sulfate adenylyltransferase (ATP) activity
NicSoilB11_30240	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NicSoilB11_30260	COG2860	membrane
NicSoilB11_30290	COG0142	geranyltranstransferase activity
NicSoilB11_30310	COG2226	methyltransferase
NicSoilB11_30320	COG1169	isochorismate synthase
NicSoilB11_30340	COG0765	amino acid transport
NicSoilB11_30360	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NicSoilB11_30400	COG4948	Mandelate Racemase Muconate Lactonizing
NicSoilB11_30410	COG0598	Magnesium transport protein CorA
NicSoilB11_30430	COG3559	Exporter of polyketide antibiotics
NicSoilB11_30440	COG1131	(ABC) transporter
NicSoilB11_30450	COG2814	Major facilitator Superfamily
NicSoilB11_30530	COG2072	flavoprotein involved in K transport
NicSoilB11_30620	COG0492	ferredoxin-NADP+ reductase activity
NicSoilB11_30630	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NicSoilB11_30700	COG1316	TRANSCRIPTIONal
NicSoilB11_30740	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NicSoilB11_30740	COG2755	lipolytic protein G-D-S-L family
NicSoilB11_30770	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NicSoilB11_30780	COG3795	YCII-related domain
NicSoilB11_30790	COG4941	Belongs to the sigma-70 factor family
NicSoilB11_30830	COG0508	dehydrogenase complex catalyzes the overall conversion of
NicSoilB11_30840	COG0022	dehydrogenase e1 component
NicSoilB11_30970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NicSoilB11_30990	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NicSoilB11_31010	COG1063	alcohol dehydrogenase
NicSoilB11_31020	COG2017	converts alpha-aldose to the beta-anomer
NicSoilB11_31070	COG0028	Belongs to the TPP enzyme family
NicSoilB11_31110	COG3387	PFAM Glycoside hydrolase 15-related
NicSoilB11_31160	COG0584	glycerophosphoryl diester phosphodiesterase
NicSoilB11_31170	COG2801	Transposase and inactivated derivatives
NicSoilB11_31190	COG0596	Alpha beta hydrolase
NicSoilB11_31290	COG0076	glutamate decarboxylase activity
NicSoilB11_31310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NicSoilB11_31320	COG0765	amino acid transport
NicSoilB11_31340	COG1304	FMN binding
NicSoilB11_31350	COG0076	glutamate decarboxylase activity
NicSoilB11_31430	COG0489	protein tyrosine kinase activity
NicSoilB11_31440	COG0438	transferase activity, transferring glycosyl groups
NicSoilB11_31470	COG0438	transferase activity, transferring glycosyl groups
NicSoilB11_31510	COG0297	glycogen (starch) synthase activity
NicSoilB11_31540	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NicSoilB11_31580	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NicSoilB11_31590	COG1024	Enoyl-CoA hydratase
NicSoilB11_31610	COG1620	l-lactate permease
NicSoilB11_31630	COG2188	Transcriptional regulator
NicSoilB11_31640	COG0277	FAD linked oxidase domain protein
NicSoilB11_31660	COG1620	l-lactate permease
NicSoilB11_31670	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NicSoilB11_31680	COG1024	Enoyl-CoA hydratase
NicSoilB11_31690	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NicSoilB11_31700	COG2151	metal-sulfur cluster biosynthetic enzyme
NicSoilB11_31710	COG3396	Phenylacetate-CoA oxygenase
NicSoilB11_31720	COG3460	Phenylacetate-CoA oxygenase
NicSoilB11_31730	COG3396	Phenylacetate-CoA oxygenase
NicSoilB11_31840	COG0667	Aldo Keto reductase
NicSoilB11_31850	COG0300	oxidoreductase activity
NicSoilB11_31890	COG0640	Transcriptional regulator
NicSoilB11_31910	COG0456	acetyltransferase
NicSoilB11_31910	COG1214	PFAM Peptidase M22, glycoprotease
NicSoilB11_31960	COG0390	transport system, permease component
NicSoilB11_32020	COG1937	Protein conserved in bacteria
NicSoilB11_32030	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NicSoilB11_32060	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NicSoilB11_32080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NicSoilB11_32110	COG0508	dehydrogenase complex catalyzes the overall conversion of
NicSoilB11_32120	COG0022	dehydrogenase e1 component
NicSoilB11_32120	COG0508	dehydrogenase complex catalyzes the overall conversion of
NicSoilB11_32130	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NicSoilB11_32140	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NicSoilB11_32250	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NicSoilB11_32280	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NicSoilB11_32290	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NicSoilB11_32320	COG3842	ATPase activity
NicSoilB11_32340	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NicSoilB11_32360	COG2217	Heavy metal translocating P-type atpase
NicSoilB11_32390	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NicSoilB11_32400	COG1316	TRANSCRIPTIONal
NicSoilB11_32420	COG0588	phosphoglycerate mutase activity
NicSoilB11_32430	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NicSoilB11_32440	COG0071	Belongs to the small heat shock protein (HSP20) family
NicSoilB11_32520	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NicSoilB11_32570	COG4948	Mandelate Racemase Muconate Lactonizing
NicSoilB11_32580	COG1802	Transcriptional regulator
NicSoilB11_32590	COG2271	Major facilitator Superfamily
NicSoilB11_32600	COG0857	belongs to the CobB CobQ family
NicSoilB11_32600	COG0280	phosphate acetyltransferase
NicSoilB11_32610	COG2050	protein possibly involved in aromatic compounds catabolism
NicSoilB11_32640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NicSoilB11_32670	COG2030	dehydratase
NicSoilB11_32670	COG1012	belongs to the aldehyde dehydrogenase family
NicSoilB11_32680	COG2050	protein possibly involved in aromatic compounds catabolism
NicSoilB11_32720	COG2755	lipolytic protein G-D-S-L family
NicSoilB11_32750	COG1250	3-hydroxyacyl-CoA dehydrogenase
NicSoilB11_32760	COG1024	Enoyl-CoA hydratase
NicSoilB11_32820	COG2146	nitrite reductase [NAD(P)H] activity
NicSoilB11_32830	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NicSoilB11_32850	COG1266	CAAX protease self-immunity
NicSoilB11_32870	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NicSoilB11_32970	COG0443	Heat shock 70 kDa protein
NicSoilB11_32980	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NicSoilB11_33000	COG0785	Cytochrome C biogenesis protein
NicSoilB11_33010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NicSoilB11_33020	COG0406	alpha-ribazole phosphatase activity
NicSoilB11_33050	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NicSoilB11_33090	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NicSoilB11_33100	COG3458	cephalosporin-C deacetylase activity
NicSoilB11_33110	COG1070	Carbohydrate kinase
NicSoilB11_33120	COG1028	Short-chain dehydrogenase reductase Sdr
NicSoilB11_33120	COG3347	Dehydrogenase
NicSoilB11_33150	COG1609	Transcriptional regulator
NicSoilB11_33200	COG2755	lipolytic protein G-D-S-L family
NicSoilB11_33210	COG0395	ABC-type sugar transport system, permease component
NicSoilB11_33220	COG4209	transmembrane transport
NicSoilB11_33230	COG1653	transport
NicSoilB11_33240	COG5578	integral membrane protein
NicSoilB11_33270	COG2814	Major facilitator Superfamily
NicSoilB11_33290	COG0395	ABC-type sugar transport system, permease component
NicSoilB11_33300	COG1175	transmembrane transport
NicSoilB11_33340	COG0395	ABC-type sugar transport system, permease component
NicSoilB11_33350	COG1175	transmembrane transport
NicSoilB11_33380	COG0673	inositol 2-dehydrogenase activity
NicSoilB11_33410	COG4948	Mandelate Racemase Muconate Lactonizing
NicSoilB11_33420	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NicSoilB11_33440	COG0673	inositol 2-dehydrogenase activity
NicSoilB11_33480	COG0640	Transcriptional regulator
NicSoilB11_33490	COG0123	including yeast histone deacetylase and acetoin utilization protein
NicSoilB11_33500	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NicSoilB11_33510	COG0569	domain protein
NicSoilB11_33530	COG0248	Ppx GppA phosphatase
NicSoilB11_33550	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NicSoilB11_33550	COG1754	DNA topoisomerase type I activity
NicSoilB11_33560	COG2890	protein-(glutamine-N5) methyltransferase activity
NicSoilB11_33590	COG1054	Belongs to the UPF0176 family
NicSoilB11_33610	COG1111	helicase
NicSoilB11_33610	COG1205	dead DEAH box helicase
NicSoilB11_33740	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NicSoilB11_33750	COG1349	DNA-binding transcription factor activity
NicSoilB11_33760	COG1609	Transcriptional regulator
NicSoilB11_33780	COG4209	transmembrane transport
NicSoilB11_33790	COG0395	ABC-type sugar transport system, permease component
NicSoilB11_33820	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NicSoilB11_33860	COG0395	ABC-type sugar transport system, permease component
NicSoilB11_33870	COG1175	transmembrane transport
NicSoilB11_33890	COG1609	Transcriptional regulator
NicSoilB11_33930	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NicSoilB11_33940	COG1408	metallophosphoesterase
NicSoilB11_33950	COG1132	(ABC) transporter
NicSoilB11_33960	COG1132	(ABC) transporter
NicSoilB11_33990	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NicSoilB11_34000	COG0151	Belongs to the GarS family
NicSoilB11_34060	COG1953	Uracil, thiamine, allantoin
NicSoilB11_34070	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
NicSoilB11_34080	COG2070	2-Nitropropane dioxygenase
NicSoilB11_34130	COG0667	Aldo Keto reductase
NicSoilB11_34140	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NicSoilB11_34140	COG2080	2 iron, 2 sulfur cluster binding
NicSoilB11_34160	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NicSoilB11_34160	COG3608	succinylglutamate desuccinylase aspartoacylase
NicSoilB11_34170	COG2252	PERMEase
NicSoilB11_34180	COG0590	tRNA wobble adenosine to inosine editing
NicSoilB11_34200	COG3285	dna ligase
NicSoilB11_34200	COG1793	dna ligase
NicSoilB11_34230	COG2233	PERMEase
NicSoilB11_34240	COG1414	Transcriptional regulator
NicSoilB11_34260	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NicSoilB11_34280	COG3257	ureidoglycine aminohydrolase activity
NicSoilB11_34330	COG3387	PFAM Glycoside hydrolase 15-related
NicSoilB11_34380	COG0484	heat shock protein binding
NicSoilB11_34400	COG0789	Transcriptional regulator
NicSoilB11_34430	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NicSoilB11_34440	COG0563	adenylate kinase activity
NicSoilB11_34460	COG0745	RESPONSE REGULATOR receiver
NicSoilB11_34470	COG2267	carboxylic ester hydrolase activity
NicSoilB11_34480	COG0640	Transcriptional regulator
NicSoilB11_34520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NicSoilB11_34610	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NicSoilB11_34610	COG4499	WXG100 protein secretion system (Wss), protein YukC
NicSoilB11_34710	COG2070	2-Nitropropane dioxygenase
NicSoilB11_34720	COG1064	alcohol dehydrogenase
NicSoilB11_34730	COG1063	alcohol dehydrogenase
NicSoilB11_34770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NicSoilB11_34790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NicSoilB11_34830	COG3739	integral membrane protein
NicSoilB11_34860	COG0129	dihydroxy-acid dehydratase activity
NicSoilB11_34900	COG2508	Transcriptional regulator
NicSoilB11_34930	COG2801	Transposase and inactivated derivatives
NicSoilB11_34970	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
NicSoilB11_35000	COG0477	Major facilitator Superfamily
NicSoilB11_35060	COG0640	Transcriptional regulator
NicSoilB11_35080	COG3866	Pectate lyase
NicSoilB11_35090	COG2755	lipolytic protein G-D-S-L family
NicSoilB11_35100	COG1053	succinate dehydrogenase
NicSoilB11_35130	COG0446	pyridine nucleotide-disulphide oxidoreductase
NicSoilB11_35130	COG1902	pentaerythritol trinitrate reductase activity
NicSoilB11_35140	COG0673	inositol 2-dehydrogenase activity
NicSoilB11_35150	COG1028	Short-chain dehydrogenase reductase Sdr
NicSoilB11_35160	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NicSoilB11_35170	COG0477	Major facilitator Superfamily
NicSoilB11_35180	COG0583	DNA-binding transcription factor activity
NicSoilB11_35210	COG0454	-acetyltransferase
NicSoilB11_35220	COG1609	Transcriptional regulator
NicSoilB11_35230	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NicSoilB11_35240	COG2814	Major facilitator Superfamily
NicSoilB11_35310	COG1960	acyl-CoA dehydrogenase activity
NicSoilB11_35320	COG0583	DNA-binding transcription factor activity
NicSoilB11_35340	COG0824	Thioesterase
NicSoilB11_35350	COG1960	acyl-CoA dehydrogenase activity
NicSoilB11_35390	COG0477	Major facilitator Superfamily
NicSoilB11_35440	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
NicSoilB11_35450	COG4251	negative regulation of phosphorylation
NicSoilB11_35480	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NicSoilB11_35490	COG2197	response regulator
NicSoilB11_35500	COG4585	Histidine kinase
NicSoilB11_35520	COG0577	efflux transmembrane transporter activity
NicSoilB11_35520	COG1136	(ABC) transporter
NicSoilB11_35540	COG4585	Histidine kinase
NicSoilB11_35590	COG3401	FG-GAP repeat protein
NicSoilB11_35610	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NicSoilB11_35660	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NicSoilB11_35690	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NicSoilB11_35700	COG1301	dicarboxylic acid transport
NicSoilB11_35720	COG1414	Transcriptional regulator
NicSoilB11_35730	COG2814	Major facilitator Superfamily
NicSoilB11_35740	COG1609	Transcriptional regulator
NicSoilB11_35750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NicSoilB11_35750	COG2190	(PTS) system
NicSoilB11_35750	COG1263	PTS System
NicSoilB11_35760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NicSoilB11_35770	COG1263	PTS System
NicSoilB11_35820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NicSoilB11_35860	COG1301	dicarboxylic acid transport
NicSoilB11_35880	COG1473	amidohydrolase
NicSoilB11_35890	COG0477	Major facilitator Superfamily
NicSoilB11_35910	COG2801	Transposase and inactivated derivatives
NicSoilB11_35930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NicSoilB11_35940	COG1621	beta-fructofuranosidase activity
NicSoilB11_35950	COG1609	Transcriptional regulator
NicSoilB11_35960	COG0395	ABC-type sugar transport system, permease component
NicSoilB11_36000	COG3622	Belongs to the hyi family
NicSoilB11_36010	COG2084	Dehydrogenase
NicSoilB11_36020	COG3960	tartronate-semialdehyde synthase activity
NicSoilB11_36030	COG1929	Belongs to the glycerate kinase type-1 family
NicSoilB11_36040	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NicSoilB11_36100	COG0745	RESPONSE REGULATOR receiver
NicSoilB11_36120	COG1366	Belongs to the anti-sigma-factor antagonist family
NicSoilB11_36150	COG2351	hydroxyisourate hydrolase activity
NicSoilB11_36170	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NicSoilB11_36210	COG2197	response regulator
NicSoilB11_36230	COG1802	Transcriptional regulator
NicSoilB11_36260	COG3404	Formiminotransferase-cyclodeaminase
NicSoilB11_36270	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NicSoilB11_36330	COG2271	Major facilitator Superfamily
NicSoilB11_36380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NicSoilB11_36420	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NicSoilB11_36500	COG3585	molybdate ion transport
NicSoilB11_36550	COG0135	phosphoribosylanthranilate isomerase activity
NicSoilB11_36580	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
NicSoilB11_36610	COG1175	transmembrane transport
NicSoilB11_36630	COG1940	carbohydrate kinase activity
NicSoilB11_36650	COG2076	Multidrug Resistance protein
NicSoilB11_36670	COG0667	Aldo Keto reductase
NicSoilB11_36710	COG0500	methyltransferase
NicSoilB11_36730	COG2807	transmembrane transport
NicSoilB11_36750	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NicSoilB11_36870	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NicSoilB11_36910	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NicSoilB11_36920	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NicSoilB11_36930	COG0069	glutamate synthase activity
NicSoilB11_36940	COG2218	PFAM glutamate synthase alpha subunit domain protein
NicSoilB11_36950	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NicSoilB11_36970	COG1609	Transcriptional regulator
NicSoilB11_36980	COG0673	inositol 2-dehydrogenase activity
NicSoilB11_37020	COG1609	Transcriptional regulator
NicSoilB11_37060	COG1175	transmembrane transport
NicSoilB11_37070	COG0395	ABC-type sugar transport system, permease component
NicSoilB11_37140	COG3226	Transcriptional regulator
NicSoilB11_37190	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NicSoilB11_37260	COG1760	l-serine dehydratase
NicSoilB11_37310	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NicSoilB11_37330	COG1940	carbohydrate kinase activity
NicSoilB11_37330	COG1846	Transcriptional regulator
NicSoilB11_37350	COG1175	transmembrane transport
NicSoilB11_37360	COG0395	ABC-type sugar transport system, permease component
NicSoilB11_37370	COG0366	Alpha amylase catalytic
NicSoilB11_37460	COG3971	2-oxopent-4-enoate hydratase activity
NicSoilB11_37500	COG1012	belongs to the aldehyde dehydrogenase family
NicSoilB11_37520	COG0789	Transcriptional regulator
NicSoilB11_37530	COG0484	heat shock protein binding
NicSoilB11_37540	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NicSoilB11_37550	COG0443	Heat shock 70 kDa protein
NicSoilB11_37590	COG2409	Drug exporters of the RND superfamily
NicSoilB11_37630	COG1280	lysine exporter protein (LysE YggA)
NicSoilB11_37660	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NicSoilB11_37750	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NicSoilB11_37760	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NicSoilB11_37780	COG1122	ATPase activity
NicSoilB11_37790	COG4721	ABC-type cobalt transport system, permease component
NicSoilB11_37800	COG4702	Belongs to the UPF0303 family
NicSoilB11_37840	COG1320	monovalent cation:proton antiporter activity
NicSoilB11_37850	COG2212	antiporter activity
NicSoilB11_37870	COG0651	ATP synthesis coupled electron transport
NicSoilB11_37880	COG1006	Multisubunit Na H antiporter MnhC subunit
NicSoilB11_37890	COG2111	Na H antiporter
NicSoilB11_37890	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NicSoilB11_37920	COG0475	glutathione-regulated potassium exporter activity
NicSoilB11_37930	COG0717	Belongs to the dCTP deaminase family
NicSoilB11_37990	COG0583	DNA-binding transcription factor activity
NicSoilB11_38010	COG1012	belongs to the aldehyde dehydrogenase family
NicSoilB11_38020	COG0531	amino acid
NicSoilB11_38030	COG0583	DNA-binding transcription factor activity
NicSoilB11_38040	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NicSoilB11_38070	COG2814	Major facilitator Superfamily
NicSoilB11_38080	COG3387	PFAM Glycoside hydrolase 15-related
NicSoilB11_38090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NicSoilB11_38100	COG0667	Aldo Keto reductase
NicSoilB11_38130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NicSoilB11_38150	COG1012	belongs to the aldehyde dehydrogenase family
NicSoilB11_38190	COG3845	ABC transporter
NicSoilB11_38240	COG1609	Transcriptional regulator
NicSoilB11_38260	COG0800	Aldolase
NicSoilB11_38290	COG0646	methionine synthase
NicSoilB11_38290	COG1410	methionine synthase
NicSoilB11_38300	COG0535	radical SAM domain protein
NicSoilB11_38380	COG2267	carboxylic ester hydrolase activity
NicSoilB11_38390	COG3265	gluconokinase activity
NicSoilB11_38410	COG2084	Dehydrogenase
NicSoilB11_38420	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
NicSoilB11_38430	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NicSoilB11_38460	COG0726	polysaccharide deacetylase
NicSoilB11_38500	COG1802	Transcriptional regulator
NicSoilB11_38520	COG3842	ATPase activity
NicSoilB11_38540	COG1840	ABC-type Fe3 transport system, periplasmic component
NicSoilB11_38560	COG0583	DNA-binding transcription factor activity
NicSoilB11_38570	COG2828	Protein conserved in bacteria
NicSoilB11_38580	COG1301	dicarboxylic acid transport
NicSoilB11_38600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NicSoilB11_38610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NicSoilB11_38640	COG1126	abc transporter atp-binding protein
NicSoilB11_38650	COG0765	amino acid transport
NicSoilB11_38680	COG0433	COG0433 Predicted ATPase
NicSoilB11_38720	COG3336	cytochrome c oxidase
NicSoilB11_38730	COG0776	regulation of translation
NicSoilB11_38750	COG1609	Transcriptional regulator
NicSoilB11_38760	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NicSoilB11_38770	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NicSoilB11_38780	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NicSoilB11_38790	COG1017	nitric oxide dioxygenase activity
NicSoilB11_38790	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NicSoilB11_38880	COG1120	ATPase activity
NicSoilB11_38890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NicSoilB11_38900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NicSoilB11_39010	COG3012	SEC-C Motif Domain Protein
NicSoilB11_39030	COG0667	Aldo Keto reductase
NicSoilB11_39110	COG0671	phosphoesterase, PA-phosphatase related
NicSoilB11_39120	COG0586	Pfam SNARE associated Golgi protein
NicSoilB11_39130	COG2186	Transcriptional regulator
NicSoilB11_39150	COG1027	Aspartate ammonia-lyase
NicSoilB11_39170	COG0405	Gamma-glutamyltransferase
NicSoilB11_39180	COG0039	L-malate dehydrogenase activity
NicSoilB11_39190	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NicSoilB11_39220	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NicSoilB11_39270	COG1280	lysine exporter protein (LysE YggA)
NicSoilB11_39310	COG0281	malic enzyme
NicSoilB11_39320	COG1309	transcriptional regulator
NicSoilB11_39350	COG0477	Major facilitator Superfamily
NicSoilB11_39360	COG0477	Major facilitator Superfamily
NicSoilB11_39370	COG2814	Major facilitator Superfamily
NicSoilB11_39400	COG0246	Mannitol dehydrogenase
NicSoilB11_39410	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NicSoilB11_39410	COG2213	PTS system mannitol-specific
NicSoilB11_39430	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NicSoilB11_39470	COG0686	Belongs to the AlaDH PNT family
NicSoilB11_39480	COG0673	inositol 2-dehydrogenase activity
NicSoilB11_39540	COG0431	NADPH-dependent FMN reductase
NicSoilB11_39560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NicSoilB11_39570	COG0589	response to stress
NicSoilB11_39610	COG0508	dehydrogenase complex catalyzes the overall conversion of
NicSoilB11_39620	COG0022	dehydrogenase e1 component
NicSoilB11_39640	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NicSoilB11_39690	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NicSoilB11_39700	COG0406	alpha-ribazole phosphatase activity
NicSoilB11_39710	COG0515	serine threonine protein kinase
NicSoilB11_39710	COG2815	serine threonine protein kinase
NicSoilB11_39750	COG1607	acyl-coa hydrolase
NicSoilB11_39760	COG1840	ABC-type Fe3 transport system, periplasmic component
NicSoilB11_39770	COG3842	ATPase activity
NicSoilB11_39780	COG1178	ABC-type Fe3 transport system permease component
NicSoilB11_39820	COG1414	Transcriptional regulator
NicSoilB11_39830	COG2814	Major facilitator Superfamily
NicSoilB11_39860	COG2271	Major facilitator Superfamily
NicSoilB11_39870	COG1802	Transcriptional regulator
NicSoilB11_39910	COG1597	lipid kinase activity
NicSoilB11_39950	COG1414	Transcriptional regulator
NicSoilB11_39960	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NicSoilB11_39970	COG0477	Major facilitator Superfamily
NicSoilB11_39980	COG1414	Transcriptional regulator
NicSoilB11_39990	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NicSoilB11_40010	COG0183	Belongs to the thiolase family
NicSoilB11_40020	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NicSoilB11_40050	COG3485	protocatechuate 3,4-dioxygenase
NicSoilB11_40060	COG3485	protocatechuate 3,4-dioxygenase
NicSoilB11_40080	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NicSoilB11_40090	COG1414	Transcriptional regulator
NicSoilB11_40100	COG0477	Major facilitator Superfamily
NicSoilB11_40110	COG1793	dna ligase
NicSoilB11_40150	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NicSoilB11_40210	COG1937	Protein conserved in bacteria
NicSoilB11_40260	COG0697	spore germination
NicSoilB11_40310	COG2259	Doxx family
NicSoilB11_40330	COG0305	Participates in initiation and elongation during chromosome replication
NicSoilB11_40390	COG0384	phenazine biosynthesis protein PhzF
NicSoilB11_40400	COG0359	binds to the 23S rRNA
NicSoilB11_40410	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NicSoilB11_40430	COG0360	Binds together with S18 to 16S ribosomal RNA
NicSoilB11_40520	COG0438	transferase activity, transferring glycosyl groups
NicSoilB11_40520	COG1216	Glycosyl transferase, family 2
NicSoilB11_40530	COG0463	Glycosyl transferase, family 2
NicSoilB11_40570	COG1362	aminopeptidase activity
NicSoilB11_40580	COG1113	amino acid transport
NicSoilB11_40620	COG0738	Major facilitator superfamily
NicSoilB11_40640	COG0488	(ABC) transporter
NicSoilB11_40650	COG0768	penicillin binding
NicSoilB11_40680	COG0406	alpha-ribazole phosphatase activity
NicSoilB11_40690	COG0617	tRNA 3'-terminal CCA addition
NicSoilB11_40730	COG0492	ferredoxin-NADP+ reductase activity
NicSoilB11_40740	COG3118	belongs to the thioredoxin family
NicSoilB11_40790	COG1192	Involved in chromosome partitioning
NicSoilB11_40800	COG0357	Ribosomal RNA small subunit methyltransferase G
NicSoilB11_40820	COG0706	membrane insertase activity
NicSoilB11_40830	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NicSoilB11_40840	COG0594	ribonuclease P activity
NicSoilB11_40850	COG0230	Belongs to the bacterial ribosomal protein bL34 family
NicSoilB11_40870	COG1902	pentaerythritol trinitrate reductase activity
NicSoilB11_40930	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NicSoilB11_40930	COG4124	Belongs to the glycosyl hydrolase 26 family
NicSoilB11_40970	COG0745	RESPONSE REGULATOR receiver
NicSoilB11_40980	COG5002	protein histidine kinase activity
NicSoilB11_41000	COG1401	restriction endodeoxyribonuclease activity
NicSoilB11_41050	COG0477	Major facilitator Superfamily
NicSoilB11_41070	COG0028	Belongs to the TPP enzyme family
NicSoilB11_41140	COG1396	sequence-specific DNA binding
NicSoilB11_41160	COG0028	Belongs to the TPP enzyme family
NicSoilB11_41180	COG0477	Major facilitator Superfamily
NicSoilB11_41250	COG1401	restriction endodeoxyribonuclease activity
NicSoilB11_41270	COG5002	protein histidine kinase activity
NicSoilB11_41280	COG0745	RESPONSE REGULATOR receiver
NicSoilB11_41320	COG4124	Belongs to the glycosyl hydrolase 26 family
NicSoilB11_41320	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NicSoilB11_41380	COG1902	pentaerythritol trinitrate reductase activity
NicSoilB11_41400	COG1609	Transcriptional regulator
NicSoilB11_41490	COG1609	Transcriptional regulator
NicSoilB11_41520	COG1175	transmembrane transport
NicSoilB11_41530	COG3833	ABC-type maltose transport systems, permease component
NicSoilB11_41540	COG0366	Alpha amylase catalytic
NicSoilB11_41550	COG0366	Alpha amylase catalytic
NicSoilB11_41760	COG3547	Transposase (IS116 IS110 IS902 family)
NicSoilB11_41880	COG3547	Transposase (IS116 IS110 IS902 family)
NicSoilB11_41910	COG1475	DNA binding
NicSoilB11_42320	COG4152	abc transporter atp-binding protein
NicSoilB11_42350	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NicSoilB11_42380	COG0601	transmembrane transport
NicSoilB11_42390	COG0444	Belongs to the ABC transporter superfamily
NicSoilB11_42420	COG3250	beta-galactosidase activity
NicSoilB11_42550	COG2755	lipolytic protein G-D-S-L family
NicSoilB11_42730	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NicSoilB11_42730	COG3608	succinylglutamate desuccinylase aspartoacylase
NicSoilB11_42750	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NicSoilB11_42930	COG3547	Transposase (IS116 IS110 IS902 family)
NicSoilB11_43060	COG2211	Major facilitator Superfamily
