locus-tag	class	description
NtRootA9_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NtRootA9_00020	COG0592	DNA-directed DNA polymerase activity
NtRootA9_00030	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
NtRootA9_00040	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NtRootA9_00050	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
NtRootA9_00060	COG0187	DNA topoisomerase II activity
NtRootA9_00070	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NtRootA9_00080	COG3266	domain, Protein
NtRootA9_00110	COG1215	transferase activity, transferring glycosyl groups
NtRootA9_00140	COG0705	Rhomboid family
NtRootA9_00150	COG2818	Glycosylase
NtRootA9_00170	COG3764	Sortase (surface protein transpeptidase)
NtRootA9_00200	COG0515	serine threonine protein kinase
NtRootA9_00210	COG0515	serine threonine protein kinase
NtRootA9_00250	COG1716	ATPase activity
NtRootA9_00260	COG1716	ATPase activity
NtRootA9_00270	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NtRootA9_00280	COG0747	negative chemotaxis
NtRootA9_00290	COG0601	transmembrane transport
NtRootA9_00300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NtRootA9_00310	COG0444	Belongs to the ABC transporter superfamily
NtRootA9_00320	COG4608	Belongs to the ABC transporter superfamily
NtRootA9_00340	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NtRootA9_00350	COG4948	Mandelate Racemase Muconate Lactonizing
NtRootA9_00360	COG0583	DNA-binding transcription factor activity
NtRootA9_00390	COG2837	iron assimilation
NtRootA9_00410	COG0672	)-iron permease
NtRootA9_00460	COG1309	transcriptional regulator
NtRootA9_00500	COG0243	molybdopterin cofactor binding
NtRootA9_00520	COG0346	lactoylglutathione lyase activity
NtRootA9_00580	COG1846	Transcriptional regulator
NtRootA9_00600	COG0277	FAD linked oxidase domain protein
NtRootA9_00610	COG1357	PFAM Pentapeptide repeats (8 copies)
NtRootA9_00620	COG0154	amidase activity
NtRootA9_00630	COG2957	Belongs to the agmatine deiminase family
NtRootA9_00650	COG1162	GTPase activity
NtRootA9_00670	COG1253	flavin adenine dinucleotide binding
NtRootA9_00690	COG3706	GGDEF domain
NtRootA9_00700	COG0673	inositol 2-dehydrogenase activity
NtRootA9_00720	COG0673	inositol 2-dehydrogenase activity
NtRootA9_00730	COG1609	Transcriptional regulator
NtRootA9_00750	COG0659	secondary active sulfate transmembrane transporter activity
NtRootA9_00760	COG0789	Transcriptional regulator
NtRootA9_00820	COG0436	Aminotransferase
NtRootA9_00830	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NtRootA9_00890	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NtRootA9_00980	COG0477	Major facilitator Superfamily
NtRootA9_00990	COG2188	Transcriptional regulator
NtRootA9_01010	COG2329	Antibiotic biosynthesis monooxygenase
NtRootA9_01030	COG1012	belongs to the aldehyde dehydrogenase family
NtRootA9_01040	COG2851	Citrate transporter
NtRootA9_01070	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
NtRootA9_01200	COG0457	Tetratricopeptide repeat
NtRootA9_01230	COG1316	TRANSCRIPTIONal
NtRootA9_01260	COG0747	negative chemotaxis
NtRootA9_01280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NtRootA9_01290	COG4172	Belongs to the ABC transporter superfamily
NtRootA9_01530	COG1131	(ABC) transporter
NtRootA9_01610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NtRootA9_01620	COG1116	anion transmembrane transporter activity
NtRootA9_01680	COG2186	Transcriptional regulator
NtRootA9_01690	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NtRootA9_01700	COG0477	Major facilitator Superfamily
NtRootA9_01710	COG1984	allophanate hydrolase subunit 2
NtRootA9_01720	COG4770	biotin carboxylase activity
NtRootA9_01730	COG5002	protein histidine kinase activity
NtRootA9_01760	COG1609	Transcriptional regulator
NtRootA9_01780	COG1396	sequence-specific DNA binding
NtRootA9_01790	COG1957	nucleoside hydrolase
NtRootA9_01800	COG0477	Major facilitator Superfamily
NtRootA9_01810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NtRootA9_01860	COG1846	Transcriptional regulator
NtRootA9_01890	COG1937	Protein conserved in bacteria
NtRootA9_01930	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NtRootA9_01940	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NtRootA9_02020	COG1028	Short-chain dehydrogenase reductase Sdr
NtRootA9_02030	COG2084	Dehydrogenase
NtRootA9_02040	COG0477	Major facilitator Superfamily
NtRootA9_02070	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NtRootA9_02210	COG0640	Transcriptional regulator
NtRootA9_02230	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NtRootA9_02250	COG0464	growth
NtRootA9_02270	COG0561	phosphatase activity
NtRootA9_02320	COG2200	EAL domain
NtRootA9_02320	COG2199	diguanylate cyclase activity
NtRootA9_02340	COG5002	protein histidine kinase activity
NtRootA9_02360	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NtRootA9_02390	COG1028	Short-chain dehydrogenase reductase Sdr
NtRootA9_02400	COG1929	Belongs to the glycerate kinase type-1 family
NtRootA9_02410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NtRootA9_02450	COG1028	Short-chain dehydrogenase reductase Sdr
NtRootA9_02490	COG0823	Involved in the tonB-independent uptake of proteins
NtRootA9_02510	COG0673	inositol 2-dehydrogenase activity
NtRootA9_02520	COG0673	inositol 2-dehydrogenase activity
NtRootA9_02540	COG3833	ABC-type maltose transport systems, permease component
NtRootA9_02630	COG1280	lysine exporter protein (LysE YggA)
NtRootA9_02670	COG2233	PERMEase
NtRootA9_02680	COG0778	Nitroreductase
NtRootA9_02740	COG2186	Transcriptional regulator
NtRootA9_02780	COG5416	Lipopolysaccharide assembly protein A domain
NtRootA9_02820	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NtRootA9_02820	COG0425	Belongs to the sulfur carrier protein TusA family
NtRootA9_02850	COG1597	lipid kinase activity
NtRootA9_02860	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NtRootA9_02900	COG0561	phosphatase activity
NtRootA9_03010	COG0037	tRNA processing
NtRootA9_03040	COG1609	Transcriptional regulator
NtRootA9_03050	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NtRootA9_03060	COG0302	gtp cyclohydrolase
NtRootA9_03070	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NtRootA9_03080	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NtRootA9_03140	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NtRootA9_03160	COG0693	protein deglycase activity
NtRootA9_03170	COG2814	Major facilitator Superfamily
NtRootA9_03200	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NtRootA9_03240	COG0823	Involved in the tonB-independent uptake of proteins
NtRootA9_03240	COG1506	peptidase
NtRootA9_03250	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
NtRootA9_03260	COG2376	Dihydroxyacetone kinase
NtRootA9_03270	COG1461	Dihydroxyacetone kinase
NtRootA9_03280	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NtRootA9_03280	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NtRootA9_03280	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
NtRootA9_03340	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NtRootA9_03370	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NtRootA9_03400	COG4948	Mandelate Racemase Muconate Lactonizing
NtRootA9_03420	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NtRootA9_03430	COG0583	DNA-binding transcription factor activity
NtRootA9_03470	COG0589	response to stress
NtRootA9_03560	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NtRootA9_03640	COG1476	TRANSCRIPTIONal
NtRootA9_03650	COG1609	Transcriptional regulator
NtRootA9_03680	COG1595	DNA-templated transcription, initiation
NtRootA9_03750	COG1609	Transcriptional regulator
NtRootA9_03760	COG1335	isochorismatase
NtRootA9_03770	COG0831	urea catabolic process
NtRootA9_03780	COG0832	Belongs to the urease beta subunit family
NtRootA9_03790	COG0804	urea catabolic process
NtRootA9_03800	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
NtRootA9_03810	COG0830	nickel cation binding
NtRootA9_03820	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NtRootA9_03830	COG0829	nickel cation binding
NtRootA9_03840	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
NtRootA9_03870	COG0477	Major facilitator Superfamily
NtRootA9_03890	COG1028	Short-chain dehydrogenase reductase Sdr
NtRootA9_03900	COG2376	Dihydroxyacetone kinase
NtRootA9_03910	COG0698	ribose 5-phosphate isomerase
NtRootA9_03930	COG2272	Belongs to the type-B carboxylesterase lipase family
NtRootA9_04020	COG3250	beta-galactosidase activity
NtRootA9_04050	COG3507	Belongs to the glycosyl hydrolase 43 family
NtRootA9_04100	COG0583	DNA-binding transcription factor activity
NtRootA9_04110	COG1028	Short-chain dehydrogenase reductase Sdr
NtRootA9_04110	COG3347	Dehydrogenase
NtRootA9_04120	COG1414	Transcriptional regulator
NtRootA9_04130	COG3408	Glycogen debranching enzyme
NtRootA9_04140	COG2272	Belongs to the type-B carboxylesterase lipase family
NtRootA9_04200	COG0385	Bile acid
NtRootA9_04210	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NtRootA9_04220	COG0318	PFAM AMP-dependent synthetase and ligase
NtRootA9_04230	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NtRootA9_04250	COG0179	Fumarylacetoacetate (FAA) hydrolase
NtRootA9_04260	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NtRootA9_04290	COG0110	maltose O-acetyltransferase activity
NtRootA9_04340	COG0436	Aminotransferase
NtRootA9_04350	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NtRootA9_04370	COG0583	DNA-binding transcription factor activity
NtRootA9_04380	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NtRootA9_04390	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NtRootA9_04400	COG1984	allophanate hydrolase subunit 2
NtRootA9_04410	COG0477	Major facilitator Superfamily
NtRootA9_04420	COG4221	oxidoreductase activity
NtRootA9_04440	COG1028	Short-chain dehydrogenase reductase Sdr
NtRootA9_04450	COG1063	alcohol dehydrogenase
NtRootA9_04460	COG3265	gluconokinase activity
NtRootA9_04480	COG0697	spore germination
NtRootA9_04500	COG0667	Aldo Keto reductase
NtRootA9_04560	COG2890	protein-(glutamine-N5) methyltransferase activity
NtRootA9_04610	COG0656	L-ascorbic acid biosynthetic process
NtRootA9_04620	COG3401	FG-GAP repeat protein
NtRootA9_04640	COG0395	ABC-type sugar transport system, permease component
NtRootA9_04650	COG1175	transmembrane transport
NtRootA9_04660	COG1653	transport
NtRootA9_04700	COG0667	Aldo Keto reductase
NtRootA9_04710	COG0656	L-ascorbic acid biosynthetic process
NtRootA9_04740	COG3360	Dodecin
NtRootA9_04750	COG3866	Pectate lyase
NtRootA9_04760	COG4677	pectinesterase activity
NtRootA9_04770	COG0395	ABC-type sugar transport system, permease component
NtRootA9_04780	COG1175	transmembrane transport
NtRootA9_04830	COG2186	Transcriptional regulator
NtRootA9_04850	COG2084	Dehydrogenase
NtRootA9_04860	COG2610	gluconate transmembrane transporter activity
NtRootA9_04930	COG0076	glutamate decarboxylase activity
NtRootA9_04940	COG3486	L-lysine 6-monooxygenase (NADPH) activity
NtRootA9_04970	COG0300	oxidoreductase activity
NtRootA9_04990	COG0477	Major facilitator Superfamily
NtRootA9_05010	COG1793	dna ligase
NtRootA9_05010	COG3285	dna ligase
NtRootA9_05020	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NtRootA9_05060	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NtRootA9_05060	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NtRootA9_05060	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NtRootA9_05080	COG1349	DNA-binding transcription factor activity
NtRootA9_05140	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NtRootA9_05150	COG1760	l-serine dehydratase
NtRootA9_05160	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NtRootA9_05170	COG0509	glycine decarboxylation via glycine cleavage system
NtRootA9_05180	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NtRootA9_05190	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NtRootA9_05190	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NtRootA9_05200	COG1113	amino acid transport
NtRootA9_05220	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NtRootA9_05230	COG2733	membrane
NtRootA9_05250	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NtRootA9_05340	COG4122	O-methyltransferase activity
NtRootA9_05350	COG0783	Belongs to the Dps family
NtRootA9_05400	COG1295	ribonuclease BN
NtRootA9_05460	COG1191	sigma factor activity
NtRootA9_05470	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NtRootA9_05480	COG0859	PFAM glycosyl transferase family 9
NtRootA9_05500	COG0297	glycogen (starch) synthase activity
NtRootA9_05510	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
NtRootA9_05520	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NtRootA9_05520	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NtRootA9_05550	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NtRootA9_05550	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NtRootA9_05570	COG0583	DNA-binding transcription factor activity
NtRootA9_05590	COG1028	Short-chain dehydrogenase reductase Sdr
NtRootA9_05610	COG1733	regulation of RNA biosynthetic process
NtRootA9_05620	COG0702	epimerase
NtRootA9_05660	COG2318	DinB family
NtRootA9_05680	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NtRootA9_05720	COG0179	Fumarylacetoacetate (FAA) hydrolase
NtRootA9_05730	COG0589	response to stress
NtRootA9_05770	COG3290	protein histidine kinase activity
NtRootA9_05780	COG4565	transcriptional regulatory protein
NtRootA9_05790	COG0010	Belongs to the arginase family
NtRootA9_05810	COG2252	PERMEase
NtRootA9_05850	COG0574	Belongs to the PEP-utilizing enzyme family
NtRootA9_05850	COG3848	Pyruvate phosphate dikinase
NtRootA9_05890	COG3883	PFAM NLP P60 protein
NtRootA9_05890	COG0791	NLP P60 protein
NtRootA9_05930	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NtRootA9_05930	COG1796	DNA polymerase
NtRootA9_06010	COG0366	Alpha amylase catalytic
NtRootA9_06060	COG1609	Transcriptional regulator
NtRootA9_06110	COG1024	Enoyl-CoA hydratase
NtRootA9_06130	COG1024	Enoyl-CoA hydratase
NtRootA9_06140	COG0492	ferredoxin-NADP+ reductase activity
NtRootA9_06180	COG1028	Short-chain dehydrogenase reductase Sdr
NtRootA9_06190	COG0789	Transcriptional regulator
NtRootA9_06210	COG1278	Cold shock
NtRootA9_06220	COG2197	response regulator
NtRootA9_06230	COG4585	Histidine kinase
NtRootA9_06260	COG0183	Belongs to the thiolase family
NtRootA9_06280	COG2031	fatty acid transporter
NtRootA9_06290	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NtRootA9_06310	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NtRootA9_06320	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NtRootA9_06330	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NtRootA9_06390	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NtRootA9_06390	COG0357	Ribosomal RNA small subunit methyltransferase G
NtRootA9_06400	COG0191	fructose-bisphosphate aldolase activity
NtRootA9_06440	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NtRootA9_06470	COG1595	DNA-templated transcription, initiation
NtRootA9_06490	COG1832	CoA-binding protein
NtRootA9_06510	COG2315	Protein conserved in bacteria
NtRootA9_06560	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NtRootA9_06570	COG0047	phosphoribosylformylglycinamidine synthase activity
NtRootA9_06640	COG1846	Transcriptional regulator
NtRootA9_06690	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NtRootA9_06710	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NtRootA9_06710	COG3323	Protein of unknown function (DUF1653)
NtRootA9_06730	COG1196	nuclear chromosome segregation
NtRootA9_06730	COG0741	lytic transglycosylase activity
NtRootA9_06730	COG0739	heme binding
NtRootA9_06740	COG0386	Belongs to the glutathione peroxidase family
NtRootA9_06750	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NtRootA9_06800	COG1309	transcriptional regulator
NtRootA9_06820	COG0438	transferase activity, transferring glycosyl groups
NtRootA9_06850	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NtRootA9_06870	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NtRootA9_06890	COG1476	TRANSCRIPTIONal
NtRootA9_06910	COG0642	Histidine kinase
NtRootA9_06920	COG0745	RESPONSE REGULATOR receiver
NtRootA9_06930	COG0477	Major facilitator Superfamily
NtRootA9_06950	COG1309	transcriptional regulator
NtRootA9_06970	COG0028	Belongs to the TPP enzyme family
NtRootA9_06980	COG0351	phosphomethylpyrimidine kinase
NtRootA9_07040	COG0343	queuine tRNA-ribosyltransferase activity
NtRootA9_07100	COG1621	beta-fructofuranosidase activity
NtRootA9_07110	COG3842	ATPase activity
NtRootA9_07160	COG1960	acyl-CoA dehydrogenase activity
NtRootA9_07190	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NtRootA9_07210	COG0586	Pfam SNARE associated Golgi protein
NtRootA9_07220	COG0564	pseudouridine synthase activity
NtRootA9_07260	COG2364	Membrane
NtRootA9_07270	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NtRootA9_07280	COG1201	RNA secondary structure unwinding
NtRootA9_07290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NtRootA9_07290	COG0723	plastoquinol--plastocyanin reductase activity
NtRootA9_07410	COG0438	transferase activity, transferring glycosyl groups
NtRootA9_07430	COG0671	phosphoesterase, PA-phosphatase related
NtRootA9_07440	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NtRootA9_07470	COG2205	protein histidine kinase activity
NtRootA9_07480	COG0745	RESPONSE REGULATOR receiver
NtRootA9_07530	COG2062	phosphohistidine phosphatase, SixA
NtRootA9_07540	COG0583	DNA-binding transcription factor activity
NtRootA9_07550	COG0697	spore germination
NtRootA9_07560	COG1309	transcriptional regulator
NtRootA9_07570	COG1511	domain protein
NtRootA9_07600	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
NtRootA9_07610	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NtRootA9_07610	COG1017	nitric oxide dioxygenase activity
NtRootA9_07620	COG1959	2 iron, 2 sulfur cluster binding
NtRootA9_07650	COG0514	ATP-dependent DNA helicase (RecQ)
NtRootA9_07680	COG1505	serine-type exopeptidase activity
NtRootA9_07700	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NtRootA9_07720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NtRootA9_07740	COG0737	Belongs to the 5'-nucleotidase family
NtRootA9_07760	COG1028	Short-chain dehydrogenase reductase Sdr
NtRootA9_07760	COG3321	synthase
NtRootA9_07760	COG0604	alcohol dehydrogenase
NtRootA9_07780	COG1136	(ABC) transporter
NtRootA9_07780	COG0577	efflux transmembrane transporter activity
NtRootA9_07800	COG1966	Carbon starvation protein
NtRootA9_07840	COG0656	L-ascorbic acid biosynthetic process
NtRootA9_07920	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NtRootA9_07930	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NtRootA9_07970	COG0588	phosphoglycerate mutase activity
NtRootA9_07990	COG5002	protein histidine kinase activity
NtRootA9_08340	COG3608	succinylglutamate desuccinylase aspartoacylase
NtRootA9_08340	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NtRootA9_08370	COG1484	DNA-dependent DNA replication
NtRootA9_08440	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NtRootA9_08470	COG0179	Fumarylacetoacetate (FAA) hydrolase
NtRootA9_08520	COG0563	adenylate kinase activity
NtRootA9_08530	COG0563	adenylate kinase activity
NtRootA9_08540	COG3250	beta-galactosidase activity
NtRootA9_08560	COG1846	Transcriptional regulator
NtRootA9_08620	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NtRootA9_08620	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NtRootA9_08630	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NtRootA9_08640	COG0215	cysteine-tRNA ligase activity
NtRootA9_08690	COG0028	Belongs to the TPP enzyme family
NtRootA9_08710	COG0366	Alpha amylase catalytic
NtRootA9_08730	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NtRootA9_08750	COG0277	FAD linked oxidase domain protein
NtRootA9_08770	COG3842	ATPase activity
NtRootA9_08880	COG0783	Belongs to the Dps family
NtRootA9_08890	COG0477	Major facilitator Superfamily
NtRootA9_08910	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NtRootA9_08910	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NtRootA9_08920	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NtRootA9_08940	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
NtRootA9_08990	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NtRootA9_09020	COG1278	Cold shock
NtRootA9_09040	COG0459	protein refolding
NtRootA9_09050	COG1653	transport
NtRootA9_09060	COG0328	RNA-DNA hybrid ribonuclease activity
NtRootA9_09080	COG2205	protein histidine kinase activity
NtRootA9_09090	COG0745	RESPONSE REGULATOR receiver
NtRootA9_09100	COG0726	polysaccharide deacetylase
NtRootA9_09140	COG1061	Type III restriction enzyme res subunit
NtRootA9_09170	COG1278	Cold shock
NtRootA9_09210	COG0739	heme binding
NtRootA9_09220	COG3103	Sh3 type 3 domain protein
NtRootA9_09220	COG1388	LysM domain
NtRootA9_09220	COG0791	NLP P60 protein
NtRootA9_09250	COG0746	molybdenum cofactor guanylyltransferase activity
NtRootA9_09280	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NtRootA9_09320	COG0488	(ABC) transporter
NtRootA9_09330	COG1132	(ABC) transporter
NtRootA9_09340	COG0494	nUDIX hydrolase
NtRootA9_09380	COG0483	inositol monophosphate 1-phosphatase activity
NtRootA9_09410	COG0045	succinate-CoA ligase (ADP-forming) activity
NtRootA9_09440	COG0640	Transcriptional regulator
NtRootA9_09450	COG1942	4-Oxalocrotonate Tautomerase
NtRootA9_09480	COG3962	Belongs to the TPP enzyme family
NtRootA9_09510	COG0673	inositol 2-dehydrogenase activity
NtRootA9_09520	COG1082	Xylose isomerase domain protein TIM barrel
NtRootA9_09530	COG2814	Major facilitator Superfamily
NtRootA9_09550	COG2814	Major facilitator Superfamily
NtRootA9_09570	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
NtRootA9_09590	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NtRootA9_09610	COG3718	enzyme involved in inositol metabolism
NtRootA9_09620	COG2188	Transcriptional regulator
NtRootA9_09630	COG2814	Major facilitator Superfamily
NtRootA9_09680	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NtRootA9_09690	COG1396	sequence-specific DNA binding
NtRootA9_09730	COG0028	Belongs to the TPP enzyme family
NtRootA9_09750	COG0477	Major facilitator Superfamily
NtRootA9_09800	COG1401	restriction endodeoxyribonuclease activity
NtRootA9_09820	COG5002	protein histidine kinase activity
NtRootA9_09830	COG0745	RESPONSE REGULATOR receiver
NtRootA9_09850	COG4124	Belongs to the glycosyl hydrolase 26 family
NtRootA9_09850	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NtRootA9_09880	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NtRootA9_09930	COG1902	pentaerythritol trinitrate reductase activity
NtRootA9_09950	COG2183	response to ionizing radiation
NtRootA9_09980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NtRootA9_10010	COG1652	LysM domain
NtRootA9_10030	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NtRootA9_10040	COG0366	Alpha amylase catalytic
NtRootA9_10040	COG3103	Sh3 type 3 domain protein
NtRootA9_10050	COG1254	Belongs to the acylphosphatase family
NtRootA9_10080	COG0514	ATP-dependent DNA helicase (RecQ)
NtRootA9_10110	COG0667	Aldo Keto reductase
NtRootA9_10120	COG1063	alcohol dehydrogenase
NtRootA9_10140	COG0477	Major facilitator Superfamily
NtRootA9_10150	COG0412	Dienelactone hydrolase
NtRootA9_10160	COG0366	Alpha amylase catalytic
NtRootA9_10210	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NtRootA9_10220	COG0640	Transcriptional regulator
NtRootA9_10300	COG1082	Xylose isomerase domain protein TIM barrel
NtRootA9_10340	COG2814	Major facilitator Superfamily
NtRootA9_10390	COG3655	Transcriptional regulator
NtRootA9_10410	COG0346	lactoylglutathione lyase activity
NtRootA9_10520	COG0277	FAD linked oxidase domain protein
NtRootA9_10530	COG3619	membrane
NtRootA9_10590	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NtRootA9_10620	COG0402	S-adenosylhomocysteine deaminase activity
NtRootA9_10680	COG0477	Major facilitator Superfamily
NtRootA9_10690	COG0604	alcohol dehydrogenase
NtRootA9_10690	COG3321	synthase
NtRootA9_10740	COG0028	Belongs to the TPP enzyme family
NtRootA9_10760	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NtRootA9_10770	COG1113	amino acid transport
NtRootA9_10930	COG0456	acetyltransferase
NtRootA9_10940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NtRootA9_10950	COG0477	Major facilitator Superfamily
NtRootA9_10970	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NtRootA9_11000	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NtRootA9_11010	COG2814	Major facilitator Superfamily
NtRootA9_11060	COG2350	Protein conserved in bacteria
NtRootA9_11090	COG1349	DNA-binding transcription factor activity
NtRootA9_11100	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NtRootA9_11130	COG0601	transmembrane transport
NtRootA9_11140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NtRootA9_11150	COG4172	Belongs to the ABC transporter superfamily
NtRootA9_11160	COG4608	Belongs to the ABC transporter superfamily
NtRootA9_11170	COG0667	Aldo Keto reductase
NtRootA9_11180	COG3836	Belongs to the HpcH HpaI aldolase family
NtRootA9_11200	COG1028	Short-chain dehydrogenase reductase Sdr
NtRootA9_11210	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NtRootA9_11270	COG4942	peptidase
NtRootA9_11340	COG1126	abc transporter atp-binding protein
NtRootA9_11350	COG0765	amino acid transport
NtRootA9_11370	COG0154	amidase activity
NtRootA9_11380	COG1802	Transcriptional regulator
NtRootA9_11400	COG3540	Alkaline phosphatase
NtRootA9_11430	COG2072	flavoprotein involved in K transport
NtRootA9_11440	COG1063	alcohol dehydrogenase
NtRootA9_11490	COG1914	H( )-stimulated, divalent metal cation uptake system
NtRootA9_11520	COG1278	Cold shock
NtRootA9_11590	COG3265	gluconokinase activity
NtRootA9_11600	COG2610	gluconate transmembrane transporter activity
NtRootA9_11620	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NtRootA9_11630	COG0697	spore germination
NtRootA9_11660	COG0833	amino acid
NtRootA9_11690	COG2040	homocysteine
NtRootA9_11700	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NtRootA9_11720	COG5001	Diguanylate cyclase
NtRootA9_11730	COG2261	transglycosylase associated protein
NtRootA9_11740	COG0561	phosphatase activity
NtRootA9_11820	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NtRootA9_11830	COG0438	transferase activity, transferring glycosyl groups
NtRootA9_11840	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
NtRootA9_11880	COG0477	Major facilitator Superfamily
NtRootA9_11890	COG0138	bifunctional purine biosynthesis protein purh
NtRootA9_11920	COG2838	Isocitrate dehydrogenase
NtRootA9_11940	COG0515	serine threonine protein kinase
NtRootA9_11980	COG1136	(ABC) transporter
NtRootA9_12010	COG4213	ABC transporter substrate-binding protein
NtRootA9_12050	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NtRootA9_12070	COG0531	amino acid
NtRootA9_12110	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NtRootA9_12120	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NtRootA9_12170	COG0708	Exodeoxyribonuclease III
NtRootA9_12180	COG0180	Tryptophanyl-tRNA synthetase
NtRootA9_12230	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NtRootA9_12260	COG2009	succinate dehydrogenase
NtRootA9_12280	COG1473	amidohydrolase
NtRootA9_12280	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NtRootA9_12290	COG1846	Transcriptional regulator
NtRootA9_12300	COG1764	response to oxidative stress
NtRootA9_12310	COG2130	NADP-dependent
NtRootA9_12320	COG1744	ABC transporter substrate-binding protein PnrA-like
NtRootA9_12330	COG3845	ABC transporter
NtRootA9_12340	COG4603	Belongs to the binding-protein-dependent transport system permease family
NtRootA9_12350	COG1079	Belongs to the binding-protein-dependent transport system permease family
NtRootA9_12380	COG0586	Pfam SNARE associated Golgi protein
NtRootA9_12400	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NtRootA9_12410	COG3956	TIGRFAM MazG family protein
NtRootA9_12420	COG0148	phosphopyruvate hydratase activity
NtRootA9_12530	COG0559	Belongs to the binding-protein-dependent transport system permease family
NtRootA9_12550	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NtRootA9_12570	COG2017	converts alpha-aldose to the beta-anomer
NtRootA9_12590	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NtRootA9_12610	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NtRootA9_12630	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NtRootA9_12660	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NtRootA9_12670	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NtRootA9_12740	COG0114	fumarate hydratase activity
NtRootA9_12750	COG0288	reversible hydration of carbon dioxide
NtRootA9_12770	COG1494	fructose-1,6-bisphosphatase
NtRootA9_12790	COG1482	cell wall glycoprotein biosynthetic process
NtRootA9_12800	COG1316	TRANSCRIPTIONal
NtRootA9_12910	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NtRootA9_12920	COG1376	ErfK ybiS ycfS ynhG family protein
NtRootA9_13020	COG0714	Associated with various cellular activities
NtRootA9_13030	COG0084	hydrolase, TatD family'
NtRootA9_13040	COG3583	domain protein
NtRootA9_13050	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NtRootA9_13060	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NtRootA9_13070	COG0488	(ABC) transporter
NtRootA9_13090	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NtRootA9_13110	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NtRootA9_13120	COG0193	aminoacyl-tRNA hydrolase activity
NtRootA9_13160	COG0822	iron-sulfur transferase activity
NtRootA9_13190	COG0702	epimerase
NtRootA9_13230	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NtRootA9_13260	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NtRootA9_13260	COG1648	precorrin-2 dehydrogenase activity
NtRootA9_13270	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NtRootA9_13290	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NtRootA9_13350	COG0243	molybdopterin cofactor binding
NtRootA9_13360	COG2223	nitrite transmembrane transporter activity
NtRootA9_13370	COG0477	Major facilitator Superfamily
NtRootA9_13400	COG4770	biotin carboxylase activity
NtRootA9_13410	COG0424	maF-like protein
NtRootA9_13420	COG2409	Drug exporters of the RND superfamily
NtRootA9_13450	COG1823	symporter activity
NtRootA9_13480	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NtRootA9_13490	COG1028	Short-chain dehydrogenase reductase Sdr
NtRootA9_13540	COG0714	Associated with various cellular activities
NtRootA9_13580	COG0631	protein serine/threonine phosphatase activity
NtRootA9_13620	COG1674	ftsk spoiiie
NtRootA9_13640	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NtRootA9_13650	COG0483	inositol monophosphate 1-phosphatase activity
NtRootA9_13680	COG4565	transcriptional regulatory protein
NtRootA9_13690	COG3290	protein histidine kinase activity
NtRootA9_13700	COG2851	Citrate transporter
NtRootA9_13710	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NtRootA9_13720	COG0154	amidase activity
NtRootA9_13730	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NtRootA9_13750	COG0583	DNA-binding transcription factor activity
NtRootA9_13760	COG1063	alcohol dehydrogenase
NtRootA9_13790	COG1228	amidohydrolase
NtRootA9_13840	COG2873	o-acetylhomoserine
NtRootA9_13850	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NtRootA9_13880	COG0400	carboxylic ester hydrolase activity
NtRootA9_13910	COG0423	glycine-tRNA ligase activity
NtRootA9_13960	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NtRootA9_13960	COG1017	nitric oxide dioxygenase activity
NtRootA9_13990	COG0358	DNA primase activity
NtRootA9_14020	COG2814	Major facilitator Superfamily
NtRootA9_14060	COG0438	transferase activity, transferring glycosyl groups
NtRootA9_14090	COG0052	Belongs to the universal ribosomal protein uS2 family
NtRootA9_14100	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NtRootA9_14110	COG0528	UMP kinase activity
NtRootA9_14120	COG0233	cytoplasmic translational termination
NtRootA9_14160	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NtRootA9_14180	COG3279	Response regulator of the LytR AlgR family
NtRootA9_14190	COG3275	phosphorelay sensor kinase activity
NtRootA9_14210	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NtRootA9_14230	COG1522	sequence-specific DNA binding
NtRootA9_14250	COG0022	dehydrogenase e1 component
NtRootA9_14260	COG0508	dehydrogenase complex catalyzes the overall conversion of
NtRootA9_14280	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NtRootA9_14300	COG1960	acyl-CoA dehydrogenase activity
NtRootA9_14360	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NtRootA9_14370	COG0750	zinc metalloprotease
NtRootA9_14420	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NtRootA9_14450	COG0442	prolyl-tRNA aminoacylation
NtRootA9_14500	COG0779	Required for maturation of 30S ribosomal subunits
NtRootA9_14530	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NtRootA9_14540	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NtRootA9_14560	COG0590	tRNA wobble adenosine to inosine editing
NtRootA9_14580	COG0436	Aminotransferase
NtRootA9_14590	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NtRootA9_14620	COG0196	riboflavin kinase activity
NtRootA9_14630	COG3483	tryptophan 2,3-dioxygenase activity
NtRootA9_14650	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NtRootA9_14660	COG1185	polyribonucleotide nucleotidyltransferase activity
NtRootA9_14670	COG0612	Peptidase, M16
NtRootA9_14740	COG0315	cyclic pyranopterin monophosphate synthase activity
NtRootA9_14750	COG0521	Mo-molybdopterin cofactor biosynthetic process
NtRootA9_14770	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NtRootA9_14810	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NtRootA9_14820	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NtRootA9_14830	COG1674	ftsk spoiiie
NtRootA9_14850	COG1546	Belongs to the CinA family
NtRootA9_14850	COG1058	Belongs to the CinA family
NtRootA9_14870	COG1396	sequence-specific DNA binding
NtRootA9_14900	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NtRootA9_14910	COG2137	regulation of response to DNA damage stimulus
NtRootA9_14920	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NtRootA9_14930	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NtRootA9_14940	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NtRootA9_14950	COG2813	Specifically methylates the guanine in position
NtRootA9_14960	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NtRootA9_14980	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NtRootA9_14990	COG1388	LysM domain
NtRootA9_15000	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NtRootA9_15010	COG0131	Imidazoleglycerol-phosphate dehydratase
NtRootA9_15020	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NtRootA9_15040	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NtRootA9_15080	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NtRootA9_15090	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NtRootA9_15100	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NtRootA9_15110	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NtRootA9_15130	COG2814	Major facilitator Superfamily
NtRootA9_15150	COG0494	nUDIX hydrolase
NtRootA9_15190	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NtRootA9_15200	COG0072	phenylalanine-tRNA ligase activity
NtRootA9_15200	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NtRootA9_15220	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NtRootA9_15230	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NtRootA9_15240	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NtRootA9_15250	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NtRootA9_15260	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NtRootA9_15270	COG1438	arginine binding
NtRootA9_15280	COG0137	argininosuccinate synthase activity
NtRootA9_15290	COG0165	Argininosuccinate lyase
NtRootA9_15300	COG0259	pyridoxamine-phosphate oxidase activity
NtRootA9_15320	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NtRootA9_15320	COG2169	Transcriptional regulator
NtRootA9_15340	COG2094	Belongs to the DNA glycosylase MPG family
NtRootA9_15350	COG3973	AAA domain
NtRootA9_15360	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NtRootA9_15390	COG0647	UMP catabolic process
NtRootA9_15420	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NtRootA9_15430	COG0497	DNA recombination
NtRootA9_15440	COG0504	CTP synthase activity
NtRootA9_15450	COG0494	nUDIX hydrolase
NtRootA9_15500	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NtRootA9_15510	COG2079	MmgE PrpD family protein
NtRootA9_15550	COG3290	protein histidine kinase activity
NtRootA9_15560	COG1301	dicarboxylic acid transport
NtRootA9_15580	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NtRootA9_15590	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NtRootA9_15620	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NtRootA9_15640	COG1160	GTP binding
NtRootA9_15660	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NtRootA9_15670	COG0509	glycine decarboxylation via glycine cleavage system
NtRootA9_15730	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NtRootA9_15750	COG1940	carbohydrate kinase activity
NtRootA9_15800	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
NtRootA9_15810	COG2815	serine threonine protein kinase
NtRootA9_15810	COG0515	serine threonine protein kinase
NtRootA9_15820	COG3942	CHAP domain
NtRootA9_15820	COG1388	LysM domain
NtRootA9_15850	COG0142	geranyltranstransferase activity
NtRootA9_15880	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NtRootA9_15900	COG2001	Belongs to the MraZ family
NtRootA9_15910	COG0275	rRNA processing
NtRootA9_15930	COG0768	penicillin binding
NtRootA9_15950	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NtRootA9_15960	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NtRootA9_15970	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NtRootA9_15980	COG0772	Belongs to the SEDS family
NtRootA9_15990	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NtRootA9_16000	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NtRootA9_16020	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NtRootA9_16030	COG1496	oxidoreductase activity
NtRootA9_16040	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NtRootA9_16050	COG1799	cell septum assembly
NtRootA9_16070	COG3599	regulation of cell shape
NtRootA9_16080	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NtRootA9_16100	COG0587	DNA-directed DNA polymerase activity
NtRootA9_16130	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NtRootA9_16140	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NtRootA9_16180	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NtRootA9_16190	COG0174	glutamine synthetase
NtRootA9_16200	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
NtRootA9_16250	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NtRootA9_16260	COG0321	lipoyl(octanoyl) transferase activity
NtRootA9_16280	COG1090	epimerase
NtRootA9_16300	COG4946	Tricorn protease homolog
NtRootA9_16300	COG0793	Belongs to the peptidase S41A family
NtRootA9_16310	COG1764	response to oxidative stress
NtRootA9_16330	COG0508	dehydrogenase complex catalyzes the overall conversion of
NtRootA9_16340	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NtRootA9_16350	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NtRootA9_16400	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NtRootA9_16450	COG1271	oxidase subunit
NtRootA9_16460	COG1294	oxidase, subunit
NtRootA9_16470	COG4988	ABC transporter
NtRootA9_16490	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NtRootA9_16530	COG1435	thymidine kinase activity
NtRootA9_16560	COG0756	dUTP diphosphatase activity
NtRootA9_16610	COG0569	domain protein
NtRootA9_16620	COG0531	amino acid
NtRootA9_16630	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NtRootA9_16640	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NtRootA9_16650	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NtRootA9_16680	COG0667	Aldo Keto reductase
NtRootA9_16730	COG1122	ATPase activity
NtRootA9_16740	COG1024	Enoyl-CoA hydratase
NtRootA9_16740	COG1250	3-hydroxyacyl-CoA dehydrogenase
NtRootA9_16750	COG0183	Belongs to the thiolase family
NtRootA9_16760	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
NtRootA9_16810	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NtRootA9_16840	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NtRootA9_16880	COG3135	benzoate transporter
NtRootA9_16910	COG0242	peptide deformylase activity
NtRootA9_16920	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NtRootA9_16940	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NtRootA9_16980	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NtRootA9_16980	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NtRootA9_16990	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NtRootA9_16990	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NtRootA9_17000	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NtRootA9_17010	COG0140	phosphoribosyl-ATP diphosphatase activity
NtRootA9_17020	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NtRootA9_17030	COG0107	imidazoleglycerol-phosphate synthase activity
NtRootA9_17050	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NtRootA9_17090	COG0134	indole-3-glycerol-phosphate synthase activity
NtRootA9_17100	COG0133	tryptophan synthase activity
NtRootA9_17110	COG0159	tryptophan synthase activity
NtRootA9_17120	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NtRootA9_17130	COG0070	glutamate synthase
NtRootA9_17130	COG0067	glutamate synthase
NtRootA9_17130	COG0069	glutamate synthase activity
NtRootA9_17180	COG0456	acetyltransferase
NtRootA9_17200	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
NtRootA9_17210	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
NtRootA9_17220	COG2154	pterin-4-alpha-carbinolamine dehydratase
NtRootA9_17270	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NtRootA9_17320	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NtRootA9_17340	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NtRootA9_17380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NtRootA9_17400	COG4941	Belongs to the sigma-70 factor family
NtRootA9_17410	COG0288	reversible hydration of carbon dioxide
NtRootA9_17420	COG2017	converts alpha-aldose to the beta-anomer
NtRootA9_17430	COG2160	L-arabinose isomerase activity
NtRootA9_17470	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NtRootA9_17500	COG0589	response to stress
NtRootA9_17520	COG0765	amino acid transport
NtRootA9_17530	COG0765	amino acid transport
NtRootA9_17560	COG3959	Transketolase, thiamine diphosphate binding domain
NtRootA9_17570	COG3958	Transketolase
NtRootA9_17580	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NtRootA9_17580	COG2755	lipolytic protein G-D-S-L family
NtRootA9_17600	COG2268	Band 7 protein
NtRootA9_17620	COG0277	FAD linked oxidase domain protein
NtRootA9_17630	COG0475	glutathione-regulated potassium exporter activity
NtRootA9_17680	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
NtRootA9_17720	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NtRootA9_17730	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NtRootA9_17740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NtRootA9_17770	COG0601	transmembrane transport
NtRootA9_17780	COG0747	negative chemotaxis
NtRootA9_17790	COG0277	FAD linked oxidase domain protein
NtRootA9_17830	COG1643	Atp-dependent helicase
NtRootA9_17870	COG0009	L-threonylcarbamoyladenylate synthase
NtRootA9_17930	COG2197	response regulator
NtRootA9_17990	COG2050	protein possibly involved in aromatic compounds catabolism
NtRootA9_18010	COG4552	Acetyltransferase involved in intracellular survival and related
NtRootA9_18020	COG0539	negative regulation of cytoplasmic translation
NtRootA9_18040	COG1739	Uncharacterized protein family UPF0029
NtRootA9_18050	COG0237	dephospho-CoA kinase activity
NtRootA9_18050	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NtRootA9_18060	COG0556	nucleotide-excision repair
NtRootA9_18080	COG0477	Major facilitator Superfamily
NtRootA9_18120	COG4106	trans-aconitate 2-methyltransferase activity
NtRootA9_18170	COG0546	phosphoglycolate phosphatase activity
NtRootA9_18180	COG0204	Acyl-transferase
NtRootA9_18180	COG0318	PFAM AMP-dependent synthetase and ligase
NtRootA9_18190	COG0322	excinuclease ABC activity
NtRootA9_18200	COG1660	Displays ATPase and GTPase activities
NtRootA9_18210	COG0391	Required for morphogenesis under gluconeogenic growth conditions
NtRootA9_18220	COG1481	regulation of sporulation
NtRootA9_18230	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NtRootA9_18240	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NtRootA9_18250	COG0126	phosphoglycerate kinase activity
NtRootA9_18260	COG0149	triose-phosphate isomerase activity
NtRootA9_18270	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NtRootA9_18290	COG0363	glucosamine-6-phosphate deaminase activity
NtRootA9_18320	COG0166	Belongs to the GPI family
NtRootA9_18330	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NtRootA9_18350	COG0109	protoheme IX farnesyltransferase activity
NtRootA9_18360	COG0659	secondary active sulfate transmembrane transporter activity
NtRootA9_18370	COG1612	heme a metabolic process
NtRootA9_18390	COG1131	(ABC) transporter
NtRootA9_18440	COG0396	ATPase activity
NtRootA9_18450	COG2151	metal-sulfur cluster biosynthetic enzyme
NtRootA9_18470	COG0318	PFAM AMP-dependent synthetase and ligase
NtRootA9_18480	COG0183	Belongs to the thiolase family
NtRootA9_18500	COG1122	ATPase activity
NtRootA9_18510	COG1268	BioY protein
NtRootA9_18540	COG0488	(ABC) transporter
NtRootA9_18600	COG1028	Short-chain dehydrogenase reductase Sdr
NtRootA9_18610	COG1028	Short-chain dehydrogenase reductase Sdr
NtRootA9_18620	COG0560	Phosphoserine phosphatase
NtRootA9_18620	COG3830	Belongs to the UPF0237 family
NtRootA9_18630	COG1119	ATPase activity
NtRootA9_18660	COG0254	rRNA binding
NtRootA9_18670	COG0095	Lipoate-protein ligase
NtRootA9_18690	COG2855	membrane
NtRootA9_18720	COG1305	Transglutaminase-like
NtRootA9_18750	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NtRootA9_18760	COG0297	glycogen (starch) synthase activity
NtRootA9_18800	COG1028	Short-chain dehydrogenase reductase Sdr
NtRootA9_18840	COG0435	Glutathione S-transferase
NtRootA9_18910	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NtRootA9_18950	COG0667	Aldo Keto reductase
NtRootA9_18960	COG1968	undecaprenyl-diphosphatase activity
NtRootA9_18970	COG0215	cysteine-tRNA ligase activity
NtRootA9_18990	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NtRootA9_19000	COG1994	Peptidase M50
NtRootA9_19000	COG0517	IMP dehydrogenase activity
NtRootA9_19020	COG1222	aaa ATPase
NtRootA9_19030	COG4122	O-methyltransferase activity
NtRootA9_19050	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NtRootA9_19060	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NtRootA9_19070	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NtRootA9_19080	COG0545	Peptidyl-prolyl cis-trans isomerase
NtRootA9_19120	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NtRootA9_19130	COG0805	protein transport
NtRootA9_19140	COG4581	dead DEAH box helicase
NtRootA9_19150	COG1574	metal-dependent hydrolase with the TIM-barrel fold
NtRootA9_19160	COG1216	Glycosyl transferase, family 2
NtRootA9_19210	COG0242	peptide deformylase activity
NtRootA9_19230	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NtRootA9_19250	COG3424	synthase
NtRootA9_19310	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NtRootA9_19320	COG1845	cytochrome c oxidase, subunit III
NtRootA9_19330	COG2010	Cytochrome c
NtRootA9_19340	COG0723	plastoquinol--plastocyanin reductase activity
NtRootA9_19350	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NtRootA9_19390	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NtRootA9_19400	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NtRootA9_19440	COG0167	dihydroorotate dehydrogenase activity
NtRootA9_19470	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NtRootA9_19480	COG1381	Involved in DNA repair and RecF pathway recombination
NtRootA9_19490	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NtRootA9_19500	COG3590	peptidase
NtRootA9_19510	COG1316	TRANSCRIPTIONal
NtRootA9_19520	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NtRootA9_19540	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NtRootA9_19570	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NtRootA9_19580	COG0484	heat shock protein binding
NtRootA9_19590	COG1420	regulation of RNA biosynthetic process
NtRootA9_19630	COG0481	GTPase activity
NtRootA9_19650	COG0268	Binds directly to 16S ribosomal RNA
NtRootA9_19690	COG1307	EDD domain protein, DegV family
NtRootA9_19700	COG0495	leucyl-tRNA aminoacylation
NtRootA9_19710	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NtRootA9_19720	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NtRootA9_19730	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NtRootA9_19740	COG2390	Transcriptional regulator
NtRootA9_19750	COG0656	L-ascorbic acid biosynthetic process
NtRootA9_19790	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NtRootA9_19810	COG1758	RNA polymerase activity
NtRootA9_19820	COG0194	GDP metabolic process
NtRootA9_19830	COG0194	GDP metabolic process
NtRootA9_19840	COG0284	orotidine-5'-phosphate decarboxylase activity
NtRootA9_19850	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NtRootA9_19860	COG0505	Belongs to the CarA family
NtRootA9_19880	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NtRootA9_19890	COG0540	Belongs to the ATCase OTCase family
NtRootA9_19900	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NtRootA9_19920	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NtRootA9_19930	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NtRootA9_19950	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NtRootA9_19960	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NtRootA9_19970	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NtRootA9_19980	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NtRootA9_20010	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NtRootA9_20040	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NtRootA9_20080	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NtRootA9_20090	COG0124	histidyl-tRNA synthetase
NtRootA9_20110	COG1196	nuclear chromosome segregation
NtRootA9_20130	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NtRootA9_20140	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NtRootA9_20150	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NtRootA9_20170	COG2255	four-way junction helicase activity
NtRootA9_20180	COG0632	four-way junction helicase activity
NtRootA9_20190	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NtRootA9_20200	COG0217	transcriptional regulatory protein
NtRootA9_20210	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NtRootA9_20220	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NtRootA9_20250	COG0339	signal peptide processing
NtRootA9_20260	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NtRootA9_20270	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NtRootA9_20290	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NtRootA9_20300	COG0587	DNA-directed DNA polymerase activity
NtRootA9_20330	COG0077	Prephenate dehydratase
NtRootA9_20330	COG1605	Chorismate mutase
NtRootA9_20350	COG2135	peptidase activity
NtRootA9_20380	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NtRootA9_20390	COG1695	Transcriptional regulator
NtRootA9_20450	COG1028	Short-chain dehydrogenase reductase Sdr
NtRootA9_20510	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
NtRootA9_20520	COG1234	tRNA 3'-trailer cleavage
NtRootA9_20640	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NtRootA9_20690	COG0574	Belongs to the PEP-utilizing enzyme family
NtRootA9_20690	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NtRootA9_20700	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NtRootA9_20740	COG2217	Heavy metal translocating P-type atpase
NtRootA9_20820	COG1063	alcohol dehydrogenase
NtRootA9_20860	COG1063	alcohol dehydrogenase
NtRootA9_20870	COG0768	penicillin binding
NtRootA9_20890	COG0492	ferredoxin-NADP+ reductase activity
NtRootA9_20950	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NtRootA9_20960	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NtRootA9_20970	COG1780	Probably involved in ribonucleotide reductase function
NtRootA9_21000	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NtRootA9_21030	COG0583	DNA-binding transcription factor activity
NtRootA9_21110	COG0714	Associated with various cellular activities
NtRootA9_21150	COG0492	ferredoxin-NADP+ reductase activity
NtRootA9_21180	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NtRootA9_21200	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NtRootA9_21210	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NtRootA9_21220	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NtRootA9_21230	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NtRootA9_21240	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NtRootA9_21250	COG0351	phosphomethylpyrimidine kinase
NtRootA9_21250	COG0352	thiamine-phosphate diphosphorylase activity
NtRootA9_21250	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NtRootA9_21260	COG1530	ribonuclease E activity
NtRootA9_21280	COG0105	UTP biosynthetic process
NtRootA9_21300	COG0285	dihydrofolate synthase activity
NtRootA9_21310	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NtRootA9_21340	COG0525	valine-tRNA ligase activity
NtRootA9_21350	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NtRootA9_21360	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NtRootA9_21370	COG0740	serine-type endopeptidase activity
NtRootA9_21380	COG0740	serine-type endopeptidase activity
NtRootA9_21390	COG0544	peptidyl-prolyl cis-trans isomerase activity
NtRootA9_21460	COG0668	transmembrane transport
NtRootA9_21490	COG1946	Acyl-CoA thioesterase
NtRootA9_21550	COG2115	Belongs to the xylose isomerase family
NtRootA9_21560	COG1070	Carbohydrate kinase
NtRootA9_21590	COG0673	inositol 2-dehydrogenase activity
NtRootA9_21600	COG1609	Transcriptional regulator
NtRootA9_21610	COG2755	lipolytic protein G-D-S-L family
NtRootA9_21610	COG0657	acetylesterase activity
NtRootA9_21650	COG0242	peptide deformylase activity
NtRootA9_21700	COG3022	response to hydroperoxide
NtRootA9_21720	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NtRootA9_21730	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NtRootA9_21750	COG1045	serine acetyltransferase
NtRootA9_21760	COG0300	oxidoreductase activity
NtRootA9_21770	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NtRootA9_21830	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
NtRootA9_21860	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NtRootA9_21870	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NtRootA9_21880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NtRootA9_21900	COG4974	Belongs to the 'phage' integrase family
NtRootA9_21930	COG0792	nuclease activity
NtRootA9_21950	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NtRootA9_21970	COG0681	Belongs to the peptidase S26 family
NtRootA9_21980	COG0335	large ribosomal subunit rRNA binding
NtRootA9_21990	COG0336	Belongs to the RNA methyltransferase TrmD family
NtRootA9_22000	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NtRootA9_22010	COG1837	Belongs to the UPF0109 family
NtRootA9_22020	COG0228	four-way junction DNA binding
NtRootA9_22040	COG2514	catechol 2,3-dioxygenase activity
NtRootA9_22090	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NtRootA9_22120	COG2814	Major facilitator Superfamily
NtRootA9_22150	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NtRootA9_22160	COG0571	ribonuclease III activity
NtRootA9_22170	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NtRootA9_22190	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NtRootA9_22220	COG0742	ribosomal rna small subunit methyltransferase
NtRootA9_22230	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NtRootA9_22270	COG1181	Belongs to the D-alanine--D-alanine ligase family
NtRootA9_22280	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NtRootA9_22300	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NtRootA9_22310	COG0066	3-isopropylmalate dehydratase activity
NtRootA9_22320	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NtRootA9_22330	COG1414	Transcriptional regulator
NtRootA9_22390	COG0647	UMP catabolic process
NtRootA9_22400	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NtRootA9_22410	COG0179	Fumarylacetoacetate (FAA) hydrolase
NtRootA9_22420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NtRootA9_22440	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NtRootA9_22450	COG0473	3-isopropylmalate dehydrogenase activity
NtRootA9_22460	COG4585	Histidine kinase
NtRootA9_22470	COG2197	response regulator
NtRootA9_22480	COG1136	(ABC) transporter
NtRootA9_22480	COG0577	efflux transmembrane transporter activity
NtRootA9_22510	COG0577	efflux transmembrane transporter activity
NtRootA9_22510	COG1136	(ABC) transporter
NtRootA9_22530	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NtRootA9_22540	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NtRootA9_22550	COG0440	acetolactate synthase activity
NtRootA9_22570	COG0129	dihydroxy-acid dehydratase activity
NtRootA9_22580	COG0088	Forms part of the polypeptide exit tunnel
NtRootA9_22620	COG0747	negative chemotaxis
NtRootA9_22630	COG0579	oxidoreductase
NtRootA9_22640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NtRootA9_22650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NtRootA9_22670	COG1305	Transglutaminase-like
NtRootA9_22720	COG1104	cysteine desulfurase activity
NtRootA9_22740	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NtRootA9_22750	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NtRootA9_22770	COG1113	amino acid transport
NtRootA9_22800	COG0477	Major facilitator Superfamily
NtRootA9_22830	COG0419	ATPase involved in DNA repair
NtRootA9_22900	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NtRootA9_22910	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NtRootA9_22920	COG1234	tRNA 3'-trailer cleavage
NtRootA9_22930	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NtRootA9_22950	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NtRootA9_22970	COG1335	isochorismatase
NtRootA9_23010	COG0363	glucosamine-6-phosphate deaminase activity
NtRootA9_23050	COG1902	pentaerythritol trinitrate reductase activity
NtRootA9_23120	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
NtRootA9_23140	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NtRootA9_23150	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
NtRootA9_23170	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NtRootA9_23180	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NtRootA9_23190	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NtRootA9_23200	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NtRootA9_23210	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NtRootA9_23220	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NtRootA9_23230	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NtRootA9_23240	COG0356	it plays a direct role in the translocation of protons across the membrane
NtRootA9_23310	COG2890	protein-(glutamine-N5) methyltransferase activity
NtRootA9_23320	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NtRootA9_23340	COG0083	homoserine kinase activity
NtRootA9_23350	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NtRootA9_23360	COG0460	homoserine dehydrogenase
NtRootA9_23370	COG0019	diaminopimelate decarboxylase activity
NtRootA9_23380	COG0018	arginyl-trna synthetase
NtRootA9_23410	COG0633	Ferredoxin
NtRootA9_23410	COG0543	2 iron, 2 sulfur cluster binding
NtRootA9_23470	COG1643	Atp-dependent helicase
NtRootA9_23480	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NtRootA9_23490	COG0537	adenosine 5'-monophosphoramidase activity
NtRootA9_23500	COG1064	alcohol dehydrogenase
NtRootA9_23560	COG1121	(ABC) transporter
NtRootA9_23590	COG1253	flavin adenine dinucleotide binding
NtRootA9_23600	COG0508	dehydrogenase complex catalyzes the overall conversion of
NtRootA9_23600	COG0567	Dehydrogenase, E1 component
NtRootA9_23650	COG1595	DNA-templated transcription, initiation
NtRootA9_23670	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NtRootA9_23690	COG0483	inositol monophosphate 1-phosphatase activity
NtRootA9_23700	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NtRootA9_23730	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NtRootA9_23740	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NtRootA9_23760	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NtRootA9_23770	COG2755	lipolytic protein G-D-S-L family
NtRootA9_23770	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NtRootA9_23780	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NtRootA9_23810	COG2884	Cell division ATP-binding protein ftsE
NtRootA9_23820	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NtRootA9_23910	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NtRootA9_23920	COG1088	dTDP-glucose 4,6-dehydratase activity
NtRootA9_23940	COG0463	Glycosyl transferase, family 2
NtRootA9_24040	COG1216	Glycosyl transferase, family 2
NtRootA9_24110	COG2902	Dehydrogenase
NtRootA9_24190	COG0653	protein targeting
NtRootA9_24200	COG3214	Protein conserved in bacteria
NtRootA9_24210	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NtRootA9_24230	COG5401	PFAM Sporulation and spore germination
NtRootA9_24240	COG5002	protein histidine kinase activity
NtRootA9_24290	COG0714	Associated with various cellular activities
NtRootA9_24360	COG0601	transmembrane transport
NtRootA9_24380	COG0482	sulfurtransferase activity
NtRootA9_24410	COG0484	heat shock protein binding
NtRootA9_24420	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NtRootA9_24430	COG1595	DNA-templated transcription, initiation
NtRootA9_24450	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NtRootA9_24460	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
NtRootA9_24470	COG2086	electron transfer activity
NtRootA9_24480	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NtRootA9_24500	COG1842	Phage shock protein A
NtRootA9_24510	COG0415	Belongs to the DNA photolyase family
NtRootA9_24530	COG1615	UPF0182 protein
NtRootA9_24540	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NtRootA9_24580	COG2816	NAD+ diphosphatase activity
NtRootA9_24600	COG0210	DNA helicase
NtRootA9_24600	COG0210	DNA helicase
NtRootA9_24640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NtRootA9_24650	COG0765	amino acid transport
NtRootA9_24660	COG1126	abc transporter atp-binding protein
NtRootA9_24670	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NtRootA9_24710	COG0181	hydroxymethylbilane synthase activity
NtRootA9_24720	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NtRootA9_24730	COG3253	May function as heme-dependent peroxidase
NtRootA9_24760	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NtRootA9_24770	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NtRootA9_24820	COG2022	thiamine diphosphate biosynthetic process
NtRootA9_24840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NtRootA9_24840	COG2022	thiamine diphosphate biosynthetic process
NtRootA9_24850	COG0352	thiamine-phosphate diphosphorylase activity
NtRootA9_24860	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
NtRootA9_24870	COG0513	Belongs to the DEAD box helicase family
NtRootA9_24880	COG2189	Belongs to the N(4) N(6)-methyltransferase family
NtRootA9_24900	COG0006	proline dipeptidase activity
NtRootA9_24920	COG2239	Acts as a magnesium transporter
NtRootA9_24950	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NtRootA9_24970	COG1595	DNA-templated transcription, initiation
NtRootA9_25020	COG1611	Belongs to the LOG family
NtRootA9_25030	COG1126	abc transporter atp-binding protein
NtRootA9_25050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NtRootA9_25060	COG0765	amino acid transport
NtRootA9_25070	COG0765	amino acid transport
NtRootA9_25080	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NtRootA9_25120	COG3226	Transcriptional regulator
NtRootA9_25130	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NtRootA9_25200	COG1217	gtp-binding protein TYPA
NtRootA9_25230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NtRootA9_25240	COG0601	transmembrane transport
NtRootA9_25270	COG3046	protein related to deoxyribodipyrimidine photolyase
NtRootA9_25300	COG0012	GTP binding
NtRootA9_25310	COG1322	Protein conserved in bacteria
NtRootA9_25320	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NtRootA9_25340	COG1570	exodeoxyribonuclease VII activity
NtRootA9_25350	COG1722	exodeoxyribonuclease VII activity
NtRootA9_25360	COG2326	polyphosphate kinase activity
NtRootA9_25390	COG1174	glycine betaine transport
NtRootA9_25400	COG1174	glycine betaine transport
NtRootA9_25430	COG2971	BadF BadG BcrA BcrD
NtRootA9_25440	COG0583	DNA-binding transcription factor activity
NtRootA9_25450	COG2814	Major facilitator Superfamily
NtRootA9_25490	COG0598	Magnesium transport protein CorA
NtRootA9_25520	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NtRootA9_25530	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NtRootA9_25570	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NtRootA9_25570	COG0519	Catalyzes the synthesis of GMP from XMP
NtRootA9_25610	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NtRootA9_25620	COG0516	GMP reductase activity
NtRootA9_25680	COG1132	(ABC) transporter
NtRootA9_25700	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NtRootA9_25700	COG2755	lipolytic protein G-D-S-L family
NtRootA9_25720	COG2072	flavoprotein involved in K transport
NtRootA9_25730	COG2197	response regulator
NtRootA9_25740	COG1793	dna ligase
NtRootA9_25760	COG0459	protein refolding
NtRootA9_25770	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NtRootA9_25810	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NtRootA9_25820	COG1472	Belongs to the glycosyl hydrolase 3 family
NtRootA9_25830	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NtRootA9_25840	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NtRootA9_25870	COG0802	atpase or kinase
NtRootA9_25880	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NtRootA9_25890	COG1105	Belongs to the carbohydrate kinase PfkB family
NtRootA9_25900	COG1486	melibiose metabolic process
NtRootA9_25910	COG0438	transferase activity, transferring glycosyl groups
NtRootA9_25920	COG2759	Belongs to the formate--tetrahydrofolate ligase family
NtRootA9_25970	COG0667	Aldo Keto reductase
NtRootA9_26020	COG0736	holo-[acyl-carrier-protein] synthase activity
NtRootA9_26040	COG1072	(Pantothenic acid kinase))
NtRootA9_26050	COG1876	peptidase activity
NtRootA9_26060	COG1970	mechanosensitive ion channel activity
NtRootA9_26070	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NtRootA9_26090	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NtRootA9_26090	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NtRootA9_26100	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NtRootA9_26110	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NtRootA9_26120	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NtRootA9_26180	COG0455	bacterial-type flagellum organization
NtRootA9_26270	COG2894	cell division
NtRootA9_26340	COG5002	protein histidine kinase activity
NtRootA9_26350	COG0101	tRNA pseudouridine synthase activity
NtRootA9_26360	COG0203	ribosomal protein L17
NtRootA9_26370	COG0202	RNA polymerase activity
NtRootA9_26380	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NtRootA9_26390	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NtRootA9_26400	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NtRootA9_26410	COG3191	aminopeptidase activity
NtRootA9_26460	COG3655	Transcriptional regulator
NtRootA9_26480	COG0563	adenylate kinase activity
NtRootA9_26500	COG0200	Binds to the 23S rRNA
NtRootA9_26510	COG1841	ribosomal large subunit assembly
NtRootA9_26520	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NtRootA9_26530	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NtRootA9_26540	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NtRootA9_26550	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NtRootA9_26560	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NtRootA9_26570	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NtRootA9_26580	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NtRootA9_26590	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NtRootA9_26600	COG0255	Belongs to the universal ribosomal protein uL29 family
NtRootA9_26610	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NtRootA9_26620	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NtRootA9_26630	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NtRootA9_26640	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NtRootA9_26650	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NtRootA9_26660	COG0089	rRNA binding
NtRootA9_26670	COG0088	Forms part of the polypeptide exit tunnel
NtRootA9_26680	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NtRootA9_26690	COG0051	transcription antitermination factor activity, RNA binding
NtRootA9_26700	COG2723	6-phospho-beta-galactosidase activity
NtRootA9_26730	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NtRootA9_26740	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NtRootA9_26750	COG0049	tRNA binding
NtRootA9_26760	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NtRootA9_26770	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NtRootA9_26780	COG0085	RNA polymerase activity
NtRootA9_26800	COG0183	Belongs to the thiolase family
NtRootA9_26810	COG0442	prolyl-tRNA aminoacylation
NtRootA9_26820	COG0222	ribosome binding
NtRootA9_26830	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NtRootA9_26860	COG0081	regulation of translation
NtRootA9_26870	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NtRootA9_26900	COG0436	Aminotransferase
NtRootA9_26910	COG2197	response regulator
NtRootA9_27000	COG0354	folic acid binding
NtRootA9_27020	COG3485	protocatechuate 3,4-dioxygenase
NtRootA9_27050	COG0745	RESPONSE REGULATOR receiver
NtRootA9_27060	COG0456	acetyltransferase
NtRootA9_27070	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NtRootA9_27120	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NtRootA9_27160	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NtRootA9_27200	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NtRootA9_27210	COG0738	Major facilitator superfamily
NtRootA9_27230	COG2030	dehydratase
NtRootA9_27270	COG4989	oxidoreductase activity
NtRootA9_27280	COG0366	Alpha amylase catalytic
NtRootA9_27300	COG0702	epimerase
NtRootA9_27320	COG1140	nitrate reductase beta subunit
NtRootA9_27370	COG0706	membrane insertase activity
NtRootA9_27410	COG0754	glutathionylspermidine amidase activity
NtRootA9_27490	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NtRootA9_27540	COG0318	PFAM AMP-dependent synthetase and ligase
NtRootA9_27560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NtRootA9_27570	COG1131	(ABC) transporter
NtRootA9_27600	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NtRootA9_27640	COG1666	GTP binding
NtRootA9_27650	COG0501	Belongs to the peptidase M48B family
NtRootA9_27710	COG0531	amino acid
NtRootA9_27820	COG1215	transferase activity, transferring glycosyl groups
NtRootA9_27850	COG1012	belongs to the aldehyde dehydrogenase family
NtRootA9_27860	COG3835	regulator
NtRootA9_27920	COG2186	Transcriptional regulator
NtRootA9_27990	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NtRootA9_27990	COG1648	precorrin-2 dehydrogenase activity
NtRootA9_28020	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NtRootA9_28040	COG1690	Belongs to the RtcB family
NtRootA9_28060	COG2895	sulfate adenylyltransferase (ATP) activity
NtRootA9_28080	COG0175	sulfate reduction
NtRootA9_28090	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NtRootA9_28110	COG2860	membrane
NtRootA9_28140	COG0142	geranyltranstransferase activity
NtRootA9_28150	COG0644	oxidoreductase
NtRootA9_28160	COG2226	methyltransferase
NtRootA9_28170	COG1169	isochorismate synthase
NtRootA9_28190	COG0765	amino acid transport
NtRootA9_28210	COG0436	Aminotransferase
NtRootA9_28230	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NtRootA9_28250	COG4948	Mandelate Racemase Muconate Lactonizing
NtRootA9_28260	COG0598	Magnesium transport protein CorA
NtRootA9_28340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NtRootA9_28390	COG3300	MHYT domain
NtRootA9_28390	COG5001	Diguanylate cyclase
NtRootA9_28400	COG0596	Alpha beta hydrolase
NtRootA9_28410	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NtRootA9_28410	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NtRootA9_28490	COG2202	Pas domain
NtRootA9_28490	COG2205	protein histidine kinase activity
NtRootA9_28500	COG2353	YceI-like domain
NtRootA9_28510	COG2755	lipolytic protein G-D-S-L family
NtRootA9_28510	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NtRootA9_28560	COG1131	(ABC) transporter
NtRootA9_28590	COG1597	lipid kinase activity
NtRootA9_28600	COG2354	Protein conserved in bacteria
NtRootA9_28620	COG1609	Transcriptional regulator
NtRootA9_28650	COG1621	beta-fructofuranosidase activity
NtRootA9_28660	COG1609	Transcriptional regulator
NtRootA9_28670	COG0395	ABC-type sugar transport system, permease component
NtRootA9_28710	COG1028	Short-chain dehydrogenase reductase Sdr
NtRootA9_28720	COG0508	dehydrogenase complex catalyzes the overall conversion of
NtRootA9_28730	COG0022	dehydrogenase e1 component
NtRootA9_28790	COG0745	RESPONSE REGULATOR receiver
NtRootA9_28800	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NtRootA9_28820	COG0438	transferase activity, transferring glycosyl groups
NtRootA9_28820	COG0297	glycogen (starch) synthase activity
NtRootA9_28840	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NtRootA9_28980	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NtRootA9_29000	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NtRootA9_29050	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NtRootA9_29080	COG0489	protein tyrosine kinase activity
NtRootA9_29110	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NtRootA9_29130	COG0489	protein tyrosine kinase activity
NtRootA9_29210	COG4124	Belongs to the glycosyl hydrolase 26 family
NtRootA9_29210	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NtRootA9_29240	COG1024	Enoyl-CoA hydratase
NtRootA9_29250	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NtRootA9_29270	COG1620	l-lactate permease
NtRootA9_29290	COG1024	Enoyl-CoA hydratase
NtRootA9_29300	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NtRootA9_29310	COG2151	metal-sulfur cluster biosynthetic enzyme
NtRootA9_29320	COG3396	Phenylacetate-CoA oxygenase
NtRootA9_29330	COG3460	Phenylacetate-CoA oxygenase
NtRootA9_29340	COG3396	Phenylacetate-CoA oxygenase
NtRootA9_29360	COG0671	phosphoesterase, PA-phosphatase related
NtRootA9_29370	COG0586	Pfam SNARE associated Golgi protein
NtRootA9_29390	COG5002	protein histidine kinase activity
NtRootA9_29500	COG0667	Aldo Keto reductase
NtRootA9_29590	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NtRootA9_29630	COG0492	ferredoxin-NADP+ reductase activity
NtRootA9_29660	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NtRootA9_29670	COG2267	carboxylic ester hydrolase activity
NtRootA9_29690	COG2217	Heavy metal translocating P-type atpase
NtRootA9_29720	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NtRootA9_29730	COG1316	TRANSCRIPTIONal
NtRootA9_29750	COG0406	alpha-ribazole phosphatase activity
NtRootA9_29760	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NtRootA9_29770	COG0071	Belongs to the small heat shock protein (HSP20) family
NtRootA9_29810	COG0446	pyridine nucleotide-disulphide oxidoreductase
NtRootA9_29820	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NtRootA9_29830	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NtRootA9_29850	COG0280	phosphate acetyltransferase
NtRootA9_29850	COG0857	belongs to the CobB CobQ family
NtRootA9_29860	COG2050	protein possibly involved in aromatic compounds catabolism
NtRootA9_29890	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NtRootA9_29930	COG1012	belongs to the aldehyde dehydrogenase family
NtRootA9_29930	COG2030	dehydratase
NtRootA9_29940	COG2050	protein possibly involved in aromatic compounds catabolism
NtRootA9_30010	COG1250	3-hydroxyacyl-CoA dehydrogenase
NtRootA9_30020	COG1024	Enoyl-CoA hydratase
NtRootA9_30060	COG3237	CsbD-like
NtRootA9_30110	COG1266	CAAX protease self-immunity
NtRootA9_30130	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NtRootA9_30220	COG0443	Heat shock 70 kDa protein
NtRootA9_30230	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NtRootA9_30250	COG0785	Cytochrome C biogenesis protein
NtRootA9_30260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NtRootA9_30270	COG0406	alpha-ribazole phosphatase activity
NtRootA9_30280	COG2353	YceI-like domain
NtRootA9_30310	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NtRootA9_30350	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NtRootA9_30370	COG3458	cephalosporin-C deacetylase activity
NtRootA9_30380	COG2814	Major facilitator Superfamily
NtRootA9_30390	COG1556	Lactate utilization protein
NtRootA9_30400	COG1139	Iron-sulfur cluster binding protein
NtRootA9_30410	COG0247	lactate metabolic process
NtRootA9_30420	COG1070	Carbohydrate kinase
NtRootA9_30430	COG1028	Short-chain dehydrogenase reductase Sdr
NtRootA9_30430	COG3347	Dehydrogenase
NtRootA9_30440	COG4952	isomerase
NtRootA9_30450	COG3254	rhamnose metabolic process
NtRootA9_30480	COG2755	lipolytic protein G-D-S-L family
NtRootA9_30490	COG0395	ABC-type sugar transport system, permease component
NtRootA9_30500	COG4209	transmembrane transport
NtRootA9_30510	COG1653	transport
NtRootA9_30520	COG5578	integral membrane protein
NtRootA9_30530	COG0673	inositol 2-dehydrogenase activity
NtRootA9_30560	COG2814	Major facilitator Superfamily
NtRootA9_30580	COG0395	ABC-type sugar transport system, permease component
NtRootA9_30590	COG1175	transmembrane transport
NtRootA9_30650	COG0395	ABC-type sugar transport system, permease component
NtRootA9_30660	COG1175	transmembrane transport
NtRootA9_30690	COG0673	inositol 2-dehydrogenase activity
NtRootA9_30720	COG4948	Mandelate Racemase Muconate Lactonizing
NtRootA9_30730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NtRootA9_30750	COG0673	inositol 2-dehydrogenase activity
NtRootA9_30760	COG1609	Transcriptional regulator
NtRootA9_30780	COG0640	Transcriptional regulator
NtRootA9_30790	COG0123	including yeast histone deacetylase and acetoin utilization protein
NtRootA9_30800	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NtRootA9_30810	COG0569	domain protein
NtRootA9_30820	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NtRootA9_30830	COG0248	Ppx GppA phosphatase
NtRootA9_30850	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NtRootA9_30850	COG1754	DNA topoisomerase type I activity
NtRootA9_30860	COG2890	protein-(glutamine-N5) methyltransferase activity
NtRootA9_30890	COG1054	Belongs to the UPF0176 family
NtRootA9_30910	COG1205	dead DEAH box helicase
NtRootA9_30910	COG1111	helicase
NtRootA9_31010	COG0494	nUDIX hydrolase
NtRootA9_31040	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NtRootA9_31070	COG0395	ABC-type sugar transport system, permease component
NtRootA9_31080	COG1349	DNA-binding transcription factor activity
NtRootA9_31090	COG1609	Transcriptional regulator
NtRootA9_31120	COG0395	ABC-type sugar transport system, permease component
NtRootA9_31210	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NtRootA9_31220	COG1408	metallophosphoesterase
NtRootA9_31230	COG1132	(ABC) transporter
NtRootA9_31240	COG1132	(ABC) transporter
NtRootA9_31270	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NtRootA9_31280	COG0151	Belongs to the GarS family
NtRootA9_31320	COG1028	Short-chain dehydrogenase reductase Sdr
NtRootA9_31340	COG1953	Uracil, thiamine, allantoin
NtRootA9_31360	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
NtRootA9_31400	COG0667	Aldo Keto reductase
NtRootA9_31410	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NtRootA9_31430	COG3608	succinylglutamate desuccinylase aspartoacylase
NtRootA9_31430	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NtRootA9_31440	COG2252	PERMEase
NtRootA9_31450	COG0590	tRNA wobble adenosine to inosine editing
NtRootA9_31470	COG3285	dna ligase
NtRootA9_31470	COG1793	dna ligase
NtRootA9_31500	COG2233	PERMEase
NtRootA9_31510	COG1414	Transcriptional regulator
NtRootA9_31530	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NtRootA9_31550	COG3257	ureidoglycine aminohydrolase activity
NtRootA9_31590	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NtRootA9_31610	COG3387	PFAM Glycoside hydrolase 15-related
NtRootA9_31660	COG0484	heat shock protein binding
NtRootA9_31670	COG0789	Transcriptional regulator
NtRootA9_31700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NtRootA9_31710	COG0563	adenylate kinase activity
NtRootA9_31730	COG0745	RESPONSE REGULATOR receiver
NtRootA9_31790	COG2267	carboxylic ester hydrolase activity
NtRootA9_31810	COG0640	Transcriptional regulator
NtRootA9_31850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NtRootA9_31870	COG0579	oxidoreductase
NtRootA9_31950	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NtRootA9_31970	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NtRootA9_32180	COG1609	Transcriptional regulator
NtRootA9_32200	COG0395	ABC-type sugar transport system, permease component
NtRootA9_32210	COG1175	transmembrane transport
NtRootA9_32240	COG1064	alcohol dehydrogenase
NtRootA9_32250	COG1063	alcohol dehydrogenase
NtRootA9_32270	COG2133	pyrroloquinoline quinone binding
NtRootA9_32290	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NtRootA9_32300	COG1116	anion transmembrane transporter activity
NtRootA9_32310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NtRootA9_32350	COG3739	integral membrane protein
NtRootA9_32420	COG2508	Transcriptional regulator
NtRootA9_32430	COG1414	Transcriptional regulator
NtRootA9_32540	COG0454	-acetyltransferase
NtRootA9_32580	COG1737	Transcriptional regulator
NtRootA9_32600	COG1012	belongs to the aldehyde dehydrogenase family
NtRootA9_32650	COG0583	DNA-binding transcription factor activity
NtRootA9_32660	COG2828	Protein conserved in bacteria
NtRootA9_32730	COG3845	ABC transporter
NtRootA9_32740	COG3813	Protein conserved in bacteria
NtRootA9_32760	COG0488	(ABC) transporter
NtRootA9_32770	COG0646	methionine synthase
NtRootA9_32770	COG1410	methionine synthase
NtRootA9_32900	COG0129	dihydroxy-acid dehydratase activity
NtRootA9_32910	COG2329	Antibiotic biosynthesis monooxygenase
NtRootA9_32930	COG2755	lipolytic protein G-D-S-L family
NtRootA9_32930	COG3401	FG-GAP repeat protein
NtRootA9_32950	COG2186	Transcriptional regulator
NtRootA9_32960	COG1620	l-lactate permease
NtRootA9_32970	COG0247	lactate metabolic process
NtRootA9_32980	COG1139	Iron-sulfur cluster binding protein
NtRootA9_32990	COG1556	Lactate utilization protein
NtRootA9_33040	COG1175	transmembrane transport
NtRootA9_33050	COG0395	ABC-type sugar transport system, permease component
NtRootA9_33070	COG2017	converts alpha-aldose to the beta-anomer
NtRootA9_33140	COG2197	response regulator
NtRootA9_33150	COG4585	Histidine kinase
NtRootA9_33170	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NtRootA9_33210	COG4166	transmembrane transport
NtRootA9_33230	COG0444	Belongs to the ABC transporter superfamily
NtRootA9_33240	COG4608	Belongs to the ABC transporter superfamily
NtRootA9_33250	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NtRootA9_33260	COG1940	carbohydrate kinase activity
NtRootA9_33270	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NtRootA9_33280	COG1228	amidohydrolase
NtRootA9_33350	COG0363	glucosamine-6-phosphate deaminase activity
NtRootA9_33380	COG4585	Histidine kinase
NtRootA9_33440	COG3401	FG-GAP repeat protein
NtRootA9_33490	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NtRootA9_33540	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NtRootA9_33570	COG1301	dicarboxylic acid transport
NtRootA9_33600	COG2146	nitrite reductase [NAD(P)H] activity
NtRootA9_33650	COG1473	amidohydrolase
NtRootA9_33670	COG0477	Major facilitator Superfamily
NtRootA9_33680	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
NtRootA9_33690	COG3622	Belongs to the hyi family
NtRootA9_33700	COG2084	Dehydrogenase
NtRootA9_33710	COG3960	tartronate-semialdehyde synthase activity
NtRootA9_33720	COG1929	Belongs to the glycerate kinase type-1 family
NtRootA9_33730	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NtRootA9_33770	COG3415	Transposase
NtRootA9_33770	COG2801	Transposase and inactivated derivatives
NtRootA9_33820	COG0745	RESPONSE REGULATOR receiver
NtRootA9_33840	COG1366	Belongs to the anti-sigma-factor antagonist family
NtRootA9_33860	COG2205	protein histidine kinase activity
NtRootA9_33880	COG2351	hydroxyisourate hydrolase activity
NtRootA9_33890	COG1414	Transcriptional regulator
NtRootA9_33900	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NtRootA9_33930	COG2909	trisaccharide binding
NtRootA9_33980	COG3404	Formiminotransferase-cyclodeaminase
NtRootA9_33990	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NtRootA9_34010	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NtRootA9_34020	COG2271	Major facilitator Superfamily
NtRootA9_34070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NtRootA9_34110	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NtRootA9_34150	COG0542	response to heat
NtRootA9_34160	COG5640	endopeptidase activity
NtRootA9_34200	COG3585	molybdate ion transport
NtRootA9_34250	COG0135	phosphoribosylanthranilate isomerase activity
NtRootA9_34270	COG1528	Iron-storage protein
NtRootA9_34310	COG0667	Aldo Keto reductase
NtRootA9_34330	COG1012	belongs to the aldehyde dehydrogenase family
NtRootA9_34340	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NtRootA9_34360	COG0513	Belongs to the DEAD box helicase family
NtRootA9_34370	COG2813	Specifically methylates the guanine in position
NtRootA9_34390	COG2807	transmembrane transport
NtRootA9_34400	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NtRootA9_34520	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NtRootA9_34580	COG0069	glutamate synthase activity
NtRootA9_34590	COG2218	PFAM glutamate synthase alpha subunit domain protein
NtRootA9_34600	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NtRootA9_34660	COG1215	transferase activity, transferring glycosyl groups
NtRootA9_34690	COG3979	chitinase
NtRootA9_34710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NtRootA9_34790	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NtRootA9_34810	COG1175	transmembrane transport
NtRootA9_34820	COG0395	ABC-type sugar transport system, permease component
NtRootA9_34870	COG3226	Transcriptional regulator
NtRootA9_34910	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NtRootA9_34950	COG0738	Major facilitator superfamily
NtRootA9_34960	COG3226	Transcriptional regulator
NtRootA9_34970	COG0110	maltose O-acetyltransferase activity
NtRootA9_34990	COG1115	amino acid carrier protein
NtRootA9_35000	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NtRootA9_35010	COG1233	COG1233 Phytoene dehydrogenase and related
NtRootA9_35020	COG1802	Transcriptional regulator
NtRootA9_35050	COG1760	l-serine dehydratase
NtRootA9_35100	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NtRootA9_35150	COG1175	transmembrane transport
NtRootA9_35160	COG0395	ABC-type sugar transport system, permease component
NtRootA9_35170	COG0366	Alpha amylase catalytic
NtRootA9_35220	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NtRootA9_35260	COG3971	2-oxopent-4-enoate hydratase activity
NtRootA9_35310	COG1012	belongs to the aldehyde dehydrogenase family
NtRootA9_35330	COG0789	Transcriptional regulator
NtRootA9_35340	COG0484	heat shock protein binding
NtRootA9_35350	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NtRootA9_35360	COG0443	Heat shock 70 kDa protein
NtRootA9_35370	COG0640	Transcriptional regulator
NtRootA9_35380	COG2814	Major facilitator Superfamily
NtRootA9_35420	COG2409	Drug exporters of the RND superfamily
NtRootA9_35430	COG1846	Transcriptional regulator
NtRootA9_35460	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NtRootA9_35480	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NtRootA9_35580	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NtRootA9_35590	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NtRootA9_35620	COG1122	ATPase activity
NtRootA9_35630	COG4721	ABC-type cobalt transport system, permease component
NtRootA9_35640	COG4702	Belongs to the UPF0303 family
NtRootA9_35700	COG1320	monovalent cation:proton antiporter activity
NtRootA9_35710	COG2212	antiporter activity
NtRootA9_35730	COG0651	ATP synthesis coupled electron transport
NtRootA9_35740	COG1006	Multisubunit Na H antiporter MnhC subunit
NtRootA9_35750	COG2111	Na H antiporter
NtRootA9_35750	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NtRootA9_35770	COG0569	domain protein
NtRootA9_35770	COG2985	domain, Protein
NtRootA9_35780	COG0475	glutathione-regulated potassium exporter activity
NtRootA9_35790	COG0717	Belongs to the dCTP deaminase family
NtRootA9_35830	COG0583	DNA-binding transcription factor activity
NtRootA9_35850	COG1012	belongs to the aldehyde dehydrogenase family
NtRootA9_35860	COG0531	amino acid
NtRootA9_35880	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NtRootA9_35910	COG0477	Major facilitator Superfamily
NtRootA9_35920	COG3387	PFAM Glycoside hydrolase 15-related
NtRootA9_35940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NtRootA9_35950	COG0667	Aldo Keto reductase
NtRootA9_35980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NtRootA9_36030	COG1012	belongs to the aldehyde dehydrogenase family
NtRootA9_36080	COG1063	alcohol dehydrogenase
NtRootA9_36100	COG1970	mechanosensitive ion channel activity
NtRootA9_36130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NtRootA9_36140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NtRootA9_36160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NtRootA9_36180	COG1126	abc transporter atp-binding protein
NtRootA9_36190	COG0765	amino acid transport
NtRootA9_36220	COG0433	COG0433 Predicted ATPase
NtRootA9_36270	COG0776	regulation of translation
NtRootA9_36290	COG1609	Transcriptional regulator
NtRootA9_36300	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NtRootA9_36310	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NtRootA9_36320	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NtRootA9_36330	COG1017	nitric oxide dioxygenase activity
NtRootA9_36330	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NtRootA9_36410	COG1120	ATPase activity
NtRootA9_36420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NtRootA9_36430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NtRootA9_36540	COG3012	SEC-C Motif Domain Protein
NtRootA9_36560	COG0667	Aldo Keto reductase
NtRootA9_36650	COG2186	Transcriptional regulator
NtRootA9_36670	COG1027	Aspartate ammonia-lyase
NtRootA9_36690	COG0405	Gamma-glutamyltransferase
NtRootA9_36700	COG0039	L-malate dehydrogenase activity
NtRootA9_36750	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NtRootA9_36790	COG1522	sequence-specific DNA binding
NtRootA9_36800	COG1280	lysine exporter protein (LysE YggA)
NtRootA9_36840	COG0281	malic enzyme
NtRootA9_36850	COG1309	transcriptional regulator
NtRootA9_36880	COG0477	Major facilitator Superfamily
NtRootA9_36890	COG0477	Major facilitator Superfamily
NtRootA9_36900	COG3842	ATPase activity
NtRootA9_36920	COG2814	Major facilitator Superfamily
NtRootA9_36950	COG4604	ABC transporter, ATP-binding protein
NtRootA9_36960	COG4605	iron ion homeostasis
NtRootA9_36970	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NtRootA9_36980	COG4607	ABC-type enterochelin transport system periplasmic component
NtRootA9_36990	COG0246	Mannitol dehydrogenase
NtRootA9_37000	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NtRootA9_37000	COG2213	PTS system mannitol-specific
NtRootA9_37020	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NtRootA9_37050	COG4608	Belongs to the ABC transporter superfamily
NtRootA9_37060	COG0444	Belongs to the ABC transporter superfamily
NtRootA9_37070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NtRootA9_37080	COG0601	transmembrane transport
NtRootA9_37090	COG0747	negative chemotaxis
NtRootA9_37120	COG2267	carboxylic ester hydrolase activity
NtRootA9_37140	COG0686	Belongs to the AlaDH PNT family
NtRootA9_37150	COG0673	inositol 2-dehydrogenase activity
NtRootA9_37240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NtRootA9_37280	COG0508	dehydrogenase complex catalyzes the overall conversion of
NtRootA9_37290	COG0022	dehydrogenase e1 component
NtRootA9_37310	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NtRootA9_37320	COG2755	lipolytic protein G-D-S-L family
NtRootA9_37340	COG1950	PFAM Membrane protein of
NtRootA9_37380	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NtRootA9_37400	COG0515	serine threonine protein kinase
NtRootA9_37440	COG1607	acyl-coa hydrolase
NtRootA9_37450	COG1840	ABC-type Fe3 transport system, periplasmic component
NtRootA9_37460	COG3842	ATPase activity
NtRootA9_37470	COG1178	ABC-type Fe3 transport system permease component
NtRootA9_37490	COG1309	transcriptional regulator
NtRootA9_37510	COG1414	Transcriptional regulator
NtRootA9_37540	COG1597	lipid kinase activity
NtRootA9_37580	COG1414	Transcriptional regulator
NtRootA9_37590	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NtRootA9_37610	COG0183	Belongs to the thiolase family
NtRootA9_37620	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NtRootA9_37640	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NtRootA9_37650	COG3485	protocatechuate 3,4-dioxygenase
NtRootA9_37660	COG3485	protocatechuate 3,4-dioxygenase
NtRootA9_37670	COG1082	Xylose isomerase domain protein TIM barrel
NtRootA9_37670	COG3185	4-Hydroxyphenylpyruvate dioxygenase
NtRootA9_37680	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NtRootA9_37690	COG1414	Transcriptional regulator
NtRootA9_37710	COG1793	dna ligase
NtRootA9_37830	COG1937	Protein conserved in bacteria
NtRootA9_37880	COG0697	spore germination
NtRootA9_37930	COG2259	Doxx family
NtRootA9_37950	COG0305	Participates in initiation and elongation during chromosome replication
NtRootA9_37990	COG0384	phenazine biosynthesis protein PhzF
NtRootA9_38010	COG0359	binds to the 23S rRNA
NtRootA9_38020	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NtRootA9_38040	COG0360	Binds together with S18 to 16S ribosomal RNA
NtRootA9_38050	COG1113	amino acid transport
NtRootA9_38060	COG2197	response regulator
NtRootA9_38100	COG1215	transferase activity, transferring glycosyl groups
NtRootA9_38140	COG1362	aminopeptidase activity
NtRootA9_38160	COG2197	response regulator
NtRootA9_38170	COG4585	Histidine kinase
NtRootA9_38210	COG0738	Major facilitator superfamily
NtRootA9_38220	COG0488	(ABC) transporter
NtRootA9_38230	COG0768	penicillin binding
NtRootA9_38260	COG0406	alpha-ribazole phosphatase activity
NtRootA9_38270	COG0617	tRNA 3'-terminal CCA addition
NtRootA9_38310	COG0492	ferredoxin-NADP+ reductase activity
NtRootA9_38320	COG3118	belongs to the thioredoxin family
NtRootA9_38350	COG1192	Involved in chromosome partitioning
NtRootA9_38360	COG0357	Ribosomal RNA small subunit methyltransferase G
NtRootA9_38380	COG0706	membrane insertase activity
NtRootA9_38390	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NtRootA9_38400	COG0594	ribonuclease P activity
NtRootA9_38410	COG0230	Belongs to the bacterial ribosomal protein bL34 family