locus-tag	class	description
NtRootD5_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NtRootD5_00020	COG0592	DNA-directed DNA polymerase activity
NtRootD5_00030	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
NtRootD5_00040	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NtRootD5_00050	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
NtRootD5_00060	COG0187	DNA topoisomerase II activity
NtRootD5_00070	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NtRootD5_00090	COG3266	domain, Protein
NtRootD5_00110	COG1215	transferase activity, transferring glycosyl groups
NtRootD5_00140	COG0457	Tetratricopeptide repeat
NtRootD5_00140	COG0705	Rhomboid family
NtRootD5_00160	COG2818	Glycosylase
NtRootD5_00180	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NtRootD5_00180	COG2169	Transcriptional regulator
NtRootD5_00190	COG1595	DNA-templated transcription, initiation
NtRootD5_00220	COG3764	Sortase (surface protein transpeptidase)
NtRootD5_00240	COG0515	serine threonine protein kinase
NtRootD5_00250	COG0515	serine threonine protein kinase
NtRootD5_00260	COG0768	penicillin binding
NtRootD5_00290	COG1716	ATPase activity
NtRootD5_00300	COG1716	ATPase activity
NtRootD5_00390	COG1960	acyl-CoA dehydrogenase activity
NtRootD5_00420	COG0477	Major facilitator Superfamily
NtRootD5_00430	COG2175	clavaminate synthase activity
NtRootD5_00500	COG0346	lactoylglutathione lyase activity
NtRootD5_00530	COG2186	Transcriptional regulator
NtRootD5_00540	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NtRootD5_00550	COG0477	Major facilitator Superfamily
NtRootD5_00560	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NtRootD5_00570	COG4770	biotin carboxylase activity
NtRootD5_00580	COG1940	carbohydrate kinase activity
NtRootD5_00590	COG1653	transport
NtRootD5_00620	COG0395	ABC-type sugar transport system, permease component
NtRootD5_00640	COG1940	carbohydrate kinase activity
NtRootD5_00650	COG3119	arylsulfatase activity
NtRootD5_00670	COG3142	Participates in the control of copper homeostasis
NtRootD5_00680	COG0277	FAD linked oxidase domain protein
NtRootD5_00700	COG1733	regulation of RNA biosynthetic process
NtRootD5_00720	COG0385	Bile acid
NtRootD5_00730	COG0659	secondary active sulfate transmembrane transporter activity
NtRootD5_00770	COG0435	Glutathione S-transferase
NtRootD5_00780	COG0561	phosphatase activity
NtRootD5_00820	COG0584	glycerophosphoryl diester phosphodiesterase
NtRootD5_00830	COG3250	beta-galactosidase activity
NtRootD5_00840	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NtRootD5_00850	COG1929	Belongs to the glycerate kinase type-1 family
NtRootD5_00950	COG2720	vancomycin resistance protein
NtRootD5_00980	COG2135	peptidase activity
NtRootD5_01010	COG0693	protein deglycase activity
NtRootD5_01030	COG1131	(ABC) transporter
NtRootD5_01050	COG2197	response regulator
NtRootD5_01060	COG4585	Histidine kinase
NtRootD5_01090	COG2233	PERMEase
NtRootD5_01110	COG0778	Nitroreductase
NtRootD5_01150	COG3104	oligopeptide transport
NtRootD5_01170	COG3340	Belongs to the peptidase S51 family
NtRootD5_01180	COG0425	Belongs to the sulfur carrier protein TusA family
NtRootD5_01180	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NtRootD5_01210	COG1597	lipid kinase activity
NtRootD5_01220	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NtRootD5_01240	COG3973	AAA domain
NtRootD5_01250	COG0561	phosphatase activity
NtRootD5_01270	COG1191	sigma factor activity
NtRootD5_01410	COG0037	tRNA processing
NtRootD5_01440	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NtRootD5_01450	COG0302	gtp cyclohydrolase
NtRootD5_01470	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NtRootD5_01530	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NtRootD5_01550	COG2814	Major facilitator Superfamily
NtRootD5_01600	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NtRootD5_01650	COG0823	Involved in the tonB-independent uptake of proteins
NtRootD5_01650	COG1506	peptidase
NtRootD5_01660	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
NtRootD5_01690	COG2376	Dihydroxyacetone kinase
NtRootD5_01710	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
NtRootD5_01770	COG3707	response regulator
NtRootD5_01790	COG1301	dicarboxylic acid transport
NtRootD5_01830	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NtRootD5_01860	COG0671	phosphoesterase, PA-phosphatase related
NtRootD5_01910	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NtRootD5_02030	COG1609	Transcriptional regulator
NtRootD5_02070	COG0831	urea catabolic process
NtRootD5_02080	COG0832	Belongs to the urease beta subunit family
NtRootD5_02090	COG0804	urea catabolic process
NtRootD5_02100	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
NtRootD5_02110	COG0830	nickel cation binding
NtRootD5_02120	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NtRootD5_02130	COG0829	nickel cation binding
NtRootD5_02140	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
NtRootD5_02240	COG0656	L-ascorbic acid biosynthetic process
NtRootD5_02260	COG0667	Aldo Keto reductase
NtRootD5_02270	COG0656	L-ascorbic acid biosynthetic process
NtRootD5_02290	COG2826	transposase and inactivated derivatives, IS30 family
NtRootD5_02300	COG3360	Dodecin
NtRootD5_02310	COG1028	Short-chain dehydrogenase reductase Sdr
NtRootD5_02340	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NtRootD5_02350	COG0028	Belongs to the TPP enzyme family
NtRootD5_02360	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
NtRootD5_02370	COG1233	COG1233 Phytoene dehydrogenase and related
NtRootD5_02380	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NtRootD5_02400	COG1028	Short-chain dehydrogenase reductase Sdr
NtRootD5_02430	COG2186	Transcriptional regulator
NtRootD5_02460	COG2084	Dehydrogenase
NtRootD5_02470	COG2610	gluconate transmembrane transporter activity
NtRootD5_02580	COG0076	glutamate decarboxylase activity
NtRootD5_02590	COG3486	L-lysine 6-monooxygenase (NADPH) activity
NtRootD5_02680	COG1216	Glycosyl transferase, family 2
NtRootD5_02700	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NtRootD5_02710	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NtRootD5_02790	COG0346	lactoylglutathione lyase activity
NtRootD5_02810	COG0697	spore germination
NtRootD5_02820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NtRootD5_02830	COG2186	Transcriptional regulator
NtRootD5_02840	COG1653	transport
NtRootD5_02850	COG1175	transmembrane transport
NtRootD5_02870	COG4948	Mandelate Racemase Muconate Lactonizing
NtRootD5_02900	COG0477	Major facilitator Superfamily
NtRootD5_02910	COG2890	protein-(glutamine-N5) methyltransferase activity
NtRootD5_02950	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NtRootD5_02960	COG0395	ABC-type sugar transport system, permease component
NtRootD5_02970	COG1175	transmembrane transport
NtRootD5_03080	COG3226	Transcriptional regulator
NtRootD5_03100	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NtRootD5_03100	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NtRootD5_03100	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NtRootD5_03110	COG1105	Belongs to the carbohydrate kinase PfkB family
NtRootD5_03120	COG1349	DNA-binding transcription factor activity
NtRootD5_03170	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NtRootD5_03220	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NtRootD5_03290	COG1846	Transcriptional regulator
NtRootD5_03350	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
NtRootD5_03420	COG0129	dihydroxy-acid dehydratase activity
NtRootD5_03450	COG5006	permease, DMT superfamily
NtRootD5_03460	COG1609	Transcriptional regulator
NtRootD5_03470	COG0673	inositol 2-dehydrogenase activity
NtRootD5_03480	COG0673	inositol 2-dehydrogenase activity
NtRootD5_03500	COG0673	inositol 2-dehydrogenase activity
NtRootD5_03550	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NtRootD5_03560	COG1984	allophanate hydrolase subunit 2
NtRootD5_03580	COG2733	membrane
NtRootD5_03660	COG4122	O-methyltransferase activity
NtRootD5_03670	COG0454	-acetyltransferase
NtRootD5_03670	COG0456	acetyltransferase
NtRootD5_03700	COG1132	(ABC) transporter
NtRootD5_03720	COG2207	Transcriptional regulator
NtRootD5_03760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NtRootD5_03770	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NtRootD5_03780	COG1120	ATPase activity
NtRootD5_03790	COG2826	transposase and inactivated derivatives, IS30 family
NtRootD5_03820	COG1028	Short-chain dehydrogenase reductase Sdr
NtRootD5_03830	COG2826	transposase and inactivated derivatives, IS30 family
NtRootD5_03890	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NtRootD5_03930	COG2826	transposase and inactivated derivatives, IS30 family
NtRootD5_03950	COG0010	Belongs to the arginase family
NtRootD5_03960	COG2252	PERMEase
NtRootD5_04020	COG0574	Belongs to the PEP-utilizing enzyme family
NtRootD5_04020	COG3848	Pyruvate phosphate dikinase
NtRootD5_04050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NtRootD5_04240	COG0640	Transcriptional regulator
NtRootD5_04270	COG2182	Extracellular solute-binding protein
NtRootD5_04310	COG1609	Transcriptional regulator
NtRootD5_04350	COG2197	response regulator
NtRootD5_04360	COG4585	Histidine kinase
NtRootD5_04380	COG0666	response to abiotic stimulus
NtRootD5_04390	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NtRootD5_04410	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NtRootD5_04480	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NtRootD5_04500	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NtRootD5_04510	COG0303	'Molybdopterin
NtRootD5_04520	COG1063	alcohol dehydrogenase
NtRootD5_04540	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NtRootD5_04550	COG3404	Formiminotransferase-cyclodeaminase
NtRootD5_04580	COG1802	Transcriptional regulator
NtRootD5_04590	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NtRootD5_04610	COG0583	DNA-binding transcription factor activity
NtRootD5_04640	COG2197	response regulator
NtRootD5_04690	COG0415	Belongs to the DNA photolyase family
NtRootD5_04720	COG1024	Enoyl-CoA hydratase
NtRootD5_04780	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NtRootD5_04820	COG1012	belongs to the aldehyde dehydrogenase family
NtRootD5_04860	COG0789	Transcriptional regulator
NtRootD5_04870	COG1695	Transcriptional regulator
NtRootD5_04900	COG1609	Transcriptional regulator
NtRootD5_04920	COG1175	transmembrane transport
NtRootD5_04930	COG0395	ABC-type sugar transport system, permease component
NtRootD5_04950	COG0673	inositol 2-dehydrogenase activity
NtRootD5_04970	COG1904	glucuronate isomerase
NtRootD5_04980	COG0246	Mannitol dehydrogenase
NtRootD5_04990	COG4948	Mandelate Racemase Muconate Lactonizing
NtRootD5_05000	COG3265	gluconokinase activity
NtRootD5_05010	COG4213	ABC transporter substrate-binding protein
NtRootD5_05020	COG1129	ABC transporter
NtRootD5_05030	COG4214	carbohydrate transport
NtRootD5_05040	COG1609	Transcriptional regulator
NtRootD5_05050	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NtRootD5_05110	COG2826	transposase and inactivated derivatives, IS30 family
NtRootD5_05130	COG2826	transposase and inactivated derivatives, IS30 family
NtRootD5_05160	COG1120	ATPase activity
NtRootD5_05170	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NtRootD5_05180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NtRootD5_05190	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NtRootD5_05260	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NtRootD5_05270	COG2205	protein histidine kinase activity
NtRootD5_05290	COG1309	transcriptional regulator
NtRootD5_05300	COG0477	Major facilitator Superfamily
NtRootD5_05310	COG3386	PFAM SMP-30 Gluconolaconase
NtRootD5_05340	COG0488	(ABC) transporter
NtRootD5_05380	COG0477	Major facilitator Superfamily
NtRootD5_05390	COG3263	regulation of cellular component size
NtRootD5_05400	COG4932	domain protein
NtRootD5_05400	COG5492	domain, Protein
NtRootD5_05450	COG1609	Transcriptional regulator
NtRootD5_05470	COG0765	amino acid transport
NtRootD5_05480	COG1126	abc transporter atp-binding protein
NtRootD5_05490	COG0673	inositol 2-dehydrogenase activity
NtRootD5_05590	COG1832	CoA-binding protein
NtRootD5_05620	COG2315	Protein conserved in bacteria
NtRootD5_05630	COG1653	transport
NtRootD5_05640	COG1175	transmembrane transport
NtRootD5_05650	COG0395	ABC-type sugar transport system, permease component
NtRootD5_05720	COG2368	4-hydroxyphenylacetate
NtRootD5_05800	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NtRootD5_05810	COG3706	GGDEF domain
NtRootD5_05840	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NtRootD5_05850	COG0047	phosphoribosylformylglycinamidine synthase activity
NtRootD5_05890	COG3546	catalase activity
NtRootD5_05900	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NtRootD5_05960	COG1846	Transcriptional regulator
NtRootD5_05980	COG2826	transposase and inactivated derivatives, IS30 family
NtRootD5_06000	COG5416	Lipopolysaccharide assembly protein A domain
NtRootD5_06070	COG2847	Copper chaperone PCu(A)C
NtRootD5_06080	COG2837	iron assimilation
NtRootD5_06130	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NtRootD5_06150	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NtRootD5_06150	COG3323	Protein of unknown function (DUF1653)
NtRootD5_06170	COG1012	belongs to the aldehyde dehydrogenase family
NtRootD5_06200	COG1846	Transcriptional regulator
NtRootD5_06260	COG0739	heme binding
NtRootD5_06260	COG0741	lytic transglycosylase activity
NtRootD5_06260	COG1196	nuclear chromosome segregation
NtRootD5_06270	COG0386	Belongs to the glutathione peroxidase family
NtRootD5_06280	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NtRootD5_06340	COG1609	Transcriptional regulator
NtRootD5_06360	COG1175	transmembrane transport
NtRootD5_06370	COG0395	ABC-type sugar transport system, permease component
NtRootD5_06400	COG0438	transferase activity, transferring glycosyl groups
NtRootD5_06450	COG1621	beta-fructofuranosidase activity
NtRootD5_06460	COG1609	Transcriptional regulator
NtRootD5_06470	COG0395	ABC-type sugar transport system, permease component
NtRootD5_06510	COG0589	response to stress
NtRootD5_06550	COG3290	protein histidine kinase activity
NtRootD5_06560	COG4565	transcriptional regulatory protein
NtRootD5_06570	COG4702	Belongs to the UPF0303 family
NtRootD5_06590	COG0823	Involved in the tonB-independent uptake of proteins
NtRootD5_06610	COG0673	inositol 2-dehydrogenase activity
NtRootD5_06620	COG0673	inositol 2-dehydrogenase activity
NtRootD5_06640	COG0395	ABC-type sugar transport system, permease component
NtRootD5_06710	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NtRootD5_06730	COG1476	TRANSCRIPTIONal
NtRootD5_06780	COG1309	transcriptional regulator
NtRootD5_06800	COG0351	phosphomethylpyrimidine kinase
NtRootD5_06820	COG0642	Histidine kinase
NtRootD5_06830	COG0745	RESPONSE REGULATOR receiver
NtRootD5_06840	COG0477	Major facilitator Superfamily
NtRootD5_06900	COG0343	queuine tRNA-ribosyltransferase activity
NtRootD5_06980	COG1960	acyl-CoA dehydrogenase activity
NtRootD5_07040	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NtRootD5_07060	COG0586	Pfam SNARE associated Golgi protein
NtRootD5_07080	COG0564	pseudouridine synthase activity
NtRootD5_07130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NtRootD5_07140	COG2364	Membrane
NtRootD5_07170	COG1215	transferase activity, transferring glycosyl groups
NtRootD5_07190	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NtRootD5_07200	COG1201	RNA secondary structure unwinding
NtRootD5_07250	COG0475	glutathione-regulated potassium exporter activity
NtRootD5_07250	COG0569	domain protein
NtRootD5_07300	COG0438	transferase activity, transferring glycosyl groups
NtRootD5_07340	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NtRootD5_07420	COG2205	protein histidine kinase activity
NtRootD5_07430	COG0745	RESPONSE REGULATOR receiver
NtRootD5_07450	COG2062	phosphohistidine phosphatase, SixA
NtRootD5_07460	COG0583	DNA-binding transcription factor activity
NtRootD5_07470	COG0697	spore germination
NtRootD5_07490	COG1309	transcriptional regulator
NtRootD5_07500	COG1511	domain protein
NtRootD5_07540	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NtRootD5_07550	COG1940	carbohydrate kinase activity
NtRootD5_07570	COG4608	Belongs to the ABC transporter superfamily
NtRootD5_07580	COG0444	Belongs to the ABC transporter superfamily
NtRootD5_07590	COG0601	transmembrane transport
NtRootD5_07600	COG0747	negative chemotaxis
NtRootD5_07620	COG1309	transcriptional regulator
NtRootD5_07630	COG0477	Major facilitator Superfamily
NtRootD5_07640	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
NtRootD5_07650	COG0179	Fumarylacetoacetate (FAA) hydrolase
NtRootD5_07660	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
NtRootD5_07670	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NtRootD5_07670	COG1017	nitric oxide dioxygenase activity
NtRootD5_07720	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NtRootD5_07730	COG0514	ATP-dependent DNA helicase (RecQ)
NtRootD5_07740	COG0477	Major facilitator Superfamily
NtRootD5_07750	COG1505	serine-type exopeptidase activity
NtRootD5_07770	COG1113	amino acid transport
NtRootD5_07810	COG0604	alcohol dehydrogenase
NtRootD5_07810	COG1028	Short-chain dehydrogenase reductase Sdr
NtRootD5_07810	COG3321	synthase
NtRootD5_07830	COG1966	Carbon starvation protein
NtRootD5_07870	COG0656	L-ascorbic acid biosynthetic process
NtRootD5_07910	COG0673	inositol 2-dehydrogenase activity
NtRootD5_07920	COG1172	Belongs to the binding-protein-dependent transport system permease family
NtRootD5_07960	COG1609	Transcriptional regulator
NtRootD5_07990	COG0154	amidase activity
NtRootD5_08030	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NtRootD5_08090	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NtRootD5_08100	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NtRootD5_08140	COG0588	phosphoglycerate mutase activity
NtRootD5_08200	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NtRootD5_08210	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NtRootD5_08230	COG0215	cysteine-tRNA ligase activity
NtRootD5_08310	COG0366	Alpha amylase catalytic
NtRootD5_08330	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NtRootD5_08360	COG1609	Transcriptional regulator
NtRootD5_08370	COG0366	Alpha amylase catalytic
NtRootD5_08400	COG3833	ABC-type maltose transport systems, permease component
NtRootD5_08410	COG0366	Alpha amylase catalytic
NtRootD5_08420	COG0277	FAD linked oxidase domain protein
NtRootD5_08450	COG0402	S-adenosylhomocysteine deaminase activity
NtRootD5_08460	COG4608	Belongs to the ABC transporter superfamily
NtRootD5_08470	COG0444	Belongs to the ABC transporter superfamily
NtRootD5_08480	COG0601	transmembrane transport
NtRootD5_08500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NtRootD5_08510	COG0402	S-adenosylhomocysteine deaminase activity
NtRootD5_08550	COG3842	ATPase activity
NtRootD5_08650	COG0542	response to heat
NtRootD5_08660	COG1028	Short-chain dehydrogenase reductase Sdr
NtRootD5_08670	COG1609	Transcriptional regulator
NtRootD5_08680	COG0395	ABC-type sugar transport system, permease component
NtRootD5_08690	COG1175	transmembrane transport
NtRootD5_08700	COG1653	transport
NtRootD5_08720	COG1621	beta-fructofuranosidase activity
NtRootD5_08780	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NtRootD5_08800	COG3634	alkyl hydroperoxide reductase activity
NtRootD5_08850	COG1028	Short-chain dehydrogenase reductase Sdr
NtRootD5_08870	COG1960	acyl-CoA dehydrogenase activity
NtRootD5_08920	COG0579	oxidoreductase
NtRootD5_08970	COG2957	Belongs to the agmatine deiminase family
NtRootD5_08990	COG0024	Methionine aminopeptidase
NtRootD5_09020	COG0492	ferredoxin-NADP+ reductase activity
NtRootD5_09060	COG0477	Major facilitator Superfamily
NtRootD5_09080	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NtRootD5_09080	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NtRootD5_09090	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NtRootD5_09100	COG0509	glycine decarboxylation via glycine cleavage system
NtRootD5_09110	COG1760	l-serine dehydratase
NtRootD5_09120	COG1864	DNA RNA non-specific endonuclease
NtRootD5_09120	COG3591	Belongs to the peptidase S1B family
NtRootD5_09210	COG0459	protein refolding
NtRootD5_09220	COG0328	RNA-DNA hybrid ribonuclease activity
NtRootD5_09240	COG2205	protein histidine kinase activity
NtRootD5_09250	COG0745	RESPONSE REGULATOR receiver
NtRootD5_09270	COG0583	DNA-binding transcription factor activity
NtRootD5_09290	COG2132	Multicopper oxidase
NtRootD5_09340	COG1278	Cold shock
NtRootD5_09360	COG2814	Major facilitator Superfamily
NtRootD5_09370	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NtRootD5_09390	COG0739	heme binding
NtRootD5_09400	COG0791	NLP P60 protein
NtRootD5_09400	COG3103	Sh3 type 3 domain protein
NtRootD5_09400	COG1388	LysM domain
NtRootD5_09430	COG0746	molybdenum cofactor guanylyltransferase activity
NtRootD5_09460	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NtRootD5_09500	COG1126	abc transporter atp-binding protein
NtRootD5_09510	COG0765	amino acid transport
NtRootD5_09520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NtRootD5_09550	COG0488	(ABC) transporter
NtRootD5_09560	COG1132	(ABC) transporter
NtRootD5_09570	COG0494	nUDIX hydrolase
NtRootD5_09640	COG0483	inositol monophosphate 1-phosphatase activity
NtRootD5_09780	COG0045	succinate-CoA ligase (ADP-forming) activity
NtRootD5_09810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NtRootD5_09830	COG3962	Belongs to the TPP enzyme family
NtRootD5_09860	COG0673	inositol 2-dehydrogenase activity
NtRootD5_09870	COG1082	Xylose isomerase domain protein TIM barrel
NtRootD5_09880	COG3718	enzyme involved in inositol metabolism
NtRootD5_09890	COG2188	Transcriptional regulator
NtRootD5_09910	COG1172	Belongs to the binding-protein-dependent transport system permease family
NtRootD5_09960	COG0673	inositol 2-dehydrogenase activity
NtRootD5_10060	COG1396	sequence-specific DNA binding
NtRootD5_10110	COG0028	Belongs to the TPP enzyme family
NtRootD5_10120	COG0477	Major facilitator Superfamily
NtRootD5_10130	COG1234	tRNA 3'-trailer cleavage
NtRootD5_10140	COG0583	DNA-binding transcription factor activity
NtRootD5_10200	COG3142	Participates in the control of copper homeostasis
NtRootD5_10250	COG1401	restriction endodeoxyribonuclease activity
NtRootD5_10280	COG5002	protein histidine kinase activity
NtRootD5_10290	COG0745	RESPONSE REGULATOR receiver
NtRootD5_10310	COG1012	belongs to the aldehyde dehydrogenase family
NtRootD5_10340	COG1024	Enoyl-CoA hydratase
NtRootD5_10350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NtRootD5_10370	COG0477	Major facilitator Superfamily
NtRootD5_10380	COG1396	sequence-specific DNA binding
NtRootD5_10410	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NtRootD5_10430	COG3237	CsbD-like
NtRootD5_10440	COG1028	Short-chain dehydrogenase reductase Sdr
NtRootD5_10450	COG1028	Short-chain dehydrogenase reductase Sdr
NtRootD5_10490	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
NtRootD5_10510	COG1902	pentaerythritol trinitrate reductase activity
NtRootD5_10540	COG2376	Dihydroxyacetone kinase
NtRootD5_10550	COG0698	ribose 5-phosphate isomerase
NtRootD5_10560	COG1250	3-hydroxyacyl-CoA dehydrogenase
NtRootD5_10570	COG1028	Short-chain dehydrogenase reductase Sdr
NtRootD5_10580	COG2271	Major facilitator Superfamily
NtRootD5_10590	COG0149	triose-phosphate isomerase activity
NtRootD5_10670	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NtRootD5_10690	COG1254	Belongs to the acylphosphatase family
NtRootD5_10700	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
NtRootD5_10720	COG1309	transcriptional regulator
NtRootD5_10740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NtRootD5_10750	COG2186	Transcriptional regulator
NtRootD5_10760	COG0477	Major facilitator Superfamily
NtRootD5_10780	COG0640	Transcriptional regulator
NtRootD5_10800	COG4209	transmembrane transport
NtRootD5_10810	COG0395	ABC-type sugar transport system, permease component
NtRootD5_10820	COG1653	transport
NtRootD5_10920	COG1472	Belongs to the glycosyl hydrolase 3 family
NtRootD5_10930	COG0673	inositol 2-dehydrogenase activity
NtRootD5_10960	COG1609	Transcriptional regulator
NtRootD5_11000	COG0477	Major facilitator Superfamily
NtRootD5_11070	COG0640	Transcriptional regulator
NtRootD5_11100	COG1846	Transcriptional regulator
NtRootD5_11110	COG0697	spore germination
NtRootD5_11210	COG2072	flavoprotein involved in K transport
NtRootD5_11240	COG1278	Cold shock
NtRootD5_11260	COG1131	(ABC) transporter
NtRootD5_11330	COG1846	Transcriptional regulator
NtRootD5_11380	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NtRootD5_11400	COG0789	Transcriptional regulator
NtRootD5_11420	COG0484	heat shock protein binding
NtRootD5_11470	COG2271	Major facilitator Superfamily
NtRootD5_11480	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NtRootD5_11520	COG0138	bifunctional purine biosynthesis protein purh
NtRootD5_11540	COG2838	Isocitrate dehydrogenase
NtRootD5_11560	COG3639	organic phosphonate transmembrane transporter activity
NtRootD5_11570	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NtRootD5_11600	COG2188	Transcriptional regulator
NtRootD5_11630	COG0673	inositol 2-dehydrogenase activity
NtRootD5_11640	COG1136	(ABC) transporter
NtRootD5_11660	COG4213	ABC transporter substrate-binding protein
NtRootD5_11680	COG1129	ABC transporter
NtRootD5_11700	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NtRootD5_11720	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NtRootD5_11740	COG0531	amino acid
NtRootD5_11800	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NtRootD5_11810	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NtRootD5_11820	COG1131	(ABC) transporter
NtRootD5_11860	COG0708	Exodeoxyribonuclease III
NtRootD5_11870	COG0180	Tryptophanyl-tRNA synthetase
NtRootD5_11940	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NtRootD5_11970	COG2009	succinate dehydrogenase
NtRootD5_11990	COG1473	amidohydrolase
NtRootD5_11990	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NtRootD5_12000	COG1846	Transcriptional regulator
NtRootD5_12010	COG1764	response to oxidative stress
NtRootD5_12020	COG2130	NADP-dependent
NtRootD5_12030	COG1744	ABC transporter substrate-binding protein PnrA-like
NtRootD5_12040	COG3845	ABC transporter
NtRootD5_12050	COG4603	Belongs to the binding-protein-dependent transport system permease family
NtRootD5_12060	COG1079	Belongs to the binding-protein-dependent transport system permease family
NtRootD5_12100	COG0586	Pfam SNARE associated Golgi protein
NtRootD5_12110	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NtRootD5_12120	COG3956	TIGRFAM MazG family protein
NtRootD5_12130	COG0148	phosphopyruvate hydratase activity
NtRootD5_12180	COG1252	NADH dehydrogenase
NtRootD5_12230	COG2205	protein histidine kinase activity
NtRootD5_12240	COG0745	RESPONSE REGULATOR receiver
NtRootD5_12270	COG1136	(ABC) transporter
NtRootD5_12270	COG0577	efflux transmembrane transporter activity
NtRootD5_12280	COG0577	efflux transmembrane transporter activity
NtRootD5_12280	COG1136	(ABC) transporter
NtRootD5_12340	COG0559	Belongs to the binding-protein-dependent transport system permease family
NtRootD5_12360	COG0183	Belongs to the thiolase family
NtRootD5_12370	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NtRootD5_12390	COG2017	converts alpha-aldose to the beta-anomer
NtRootD5_12410	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NtRootD5_12430	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NtRootD5_12450	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NtRootD5_12480	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NtRootD5_12490	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NtRootD5_12560	COG0114	fumarate hydratase activity
NtRootD5_12570	COG0288	reversible hydration of carbon dioxide
NtRootD5_12590	COG1494	fructose-1,6-bisphosphatase
NtRootD5_12610	COG1482	cell wall glycoprotein biosynthetic process
NtRootD5_12730	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NtRootD5_12740	COG1376	ErfK ybiS ycfS ynhG family protein
NtRootD5_12750	COG1357	PFAM Pentapeptide repeats (8 copies)
NtRootD5_12850	COG0714	Associated with various cellular activities
NtRootD5_12860	COG0084	hydrolase, TatD family'
NtRootD5_12870	COG3583	domain protein
NtRootD5_12880	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NtRootD5_12890	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NtRootD5_12900	COG0488	(ABC) transporter
NtRootD5_12920	COG1309	transcriptional regulator
NtRootD5_12930	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NtRootD5_12940	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NtRootD5_12950	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NtRootD5_12960	COG0193	aminoacyl-tRNA hydrolase activity
NtRootD5_13010	COG0822	iron-sulfur transferase activity
NtRootD5_13020	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NtRootD5_13050	COG0702	epimerase
NtRootD5_13070	COG1988	membrane-bound metal-dependent
NtRootD5_13090	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NtRootD5_13110	COG0446	pyridine nucleotide-disulphide oxidoreductase
NtRootD5_13200	COG1028	Short-chain dehydrogenase reductase Sdr
NtRootD5_13240	COG1609	Transcriptional regulator
NtRootD5_13250	COG2814	Major facilitator Superfamily
NtRootD5_13270	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NtRootD5_13300	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NtRootD5_13320	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NtRootD5_13330	COG1621	beta-fructofuranosidase activity
NtRootD5_13390	COG0243	molybdopterin cofactor binding
NtRootD5_13400	COG2223	nitrite transmembrane transporter activity
NtRootD5_13410	COG0477	Major facilitator Superfamily
NtRootD5_13420	COG4770	biotin carboxylase activity
NtRootD5_13430	COG0424	maF-like protein
NtRootD5_13440	COG2409	Drug exporters of the RND superfamily
NtRootD5_13450	COG1309	transcriptional regulator
NtRootD5_13460	COG0393	Putative heavy-metal-binding
NtRootD5_13470	COG1823	symporter activity
NtRootD5_13500	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NtRootD5_13510	COG1028	Short-chain dehydrogenase reductase Sdr
NtRootD5_13520	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
NtRootD5_13520	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
NtRootD5_13570	COG0714	Associated with various cellular activities
NtRootD5_13610	COG0631	protein serine/threonine phosphatase activity
NtRootD5_13650	COG1674	ftsk spoiiie
NtRootD5_13660	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NtRootD5_13670	COG0483	inositol monophosphate 1-phosphatase activity
NtRootD5_13690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NtRootD5_13730	COG4565	transcriptional regulatory protein
NtRootD5_13750	COG2851	Citrate transporter
NtRootD5_13760	COG1316	TRANSCRIPTIONal
NtRootD5_13780	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NtRootD5_13790	COG0154	amidase activity
NtRootD5_13800	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NtRootD5_13820	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NtRootD5_13830	COG4209	transmembrane transport
NtRootD5_13840	COG0395	ABC-type sugar transport system, permease component
NtRootD5_13880	COG0583	DNA-binding transcription factor activity
NtRootD5_13890	COG1063	alcohol dehydrogenase
NtRootD5_13900	COG0156	8-amino-7-oxononanoate synthase activity
NtRootD5_13920	COG1228	amidohydrolase
NtRootD5_13930	COG0366	Alpha amylase catalytic
NtRootD5_13930	COG1470	cell adhesion involved in biofilm formation
NtRootD5_13940	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NtRootD5_13990	COG0588	phosphoglycerate mutase activity
NtRootD5_14020	COG2873	o-acetylhomoserine
NtRootD5_14030	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NtRootD5_14100	COG0423	glycine-tRNA ligase activity
NtRootD5_14140	COG0390	transport system, permease component
NtRootD5_14150	COG2205	protein histidine kinase activity
NtRootD5_14170	COG0586	Pfam SNARE associated Golgi protein
NtRootD5_14180	COG0671	phosphoesterase, PA-phosphatase related
NtRootD5_14200	COG1131	(ABC) transporter
NtRootD5_14210	COG0842	Transport permease protein
NtRootD5_14220	COG4585	Histidine kinase
NtRootD5_14230	COG2197	response regulator
NtRootD5_14260	COG0358	DNA primase activity
NtRootD5_14280	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
NtRootD5_14290	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NtRootD5_14310	COG2814	Major facilitator Superfamily
NtRootD5_14350	COG0297	glycogen (starch) synthase activity
NtRootD5_14380	COG0052	Belongs to the universal ribosomal protein uS2 family
NtRootD5_14390	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NtRootD5_14400	COG0528	UMP kinase activity
NtRootD5_14410	COG0233	cytoplasmic translational termination
NtRootD5_14420	COG0575	Belongs to the CDS family
NtRootD5_14450	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NtRootD5_14470	COG3279	Response regulator of the LytR AlgR family
NtRootD5_14480	COG3275	phosphorelay sensor kinase activity
NtRootD5_14500	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NtRootD5_14510	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NtRootD5_14510	COG1796	DNA polymerase
NtRootD5_14550	COG1522	sequence-specific DNA binding
NtRootD5_14570	COG0022	dehydrogenase e1 component
NtRootD5_14580	COG0508	dehydrogenase complex catalyzes the overall conversion of
NtRootD5_14590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NtRootD5_14620	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NtRootD5_14640	COG1960	acyl-CoA dehydrogenase activity
NtRootD5_14690	COG0673	inositol 2-dehydrogenase activity
NtRootD5_14720	COG0673	inositol 2-dehydrogenase activity
NtRootD5_14740	COG1175	transmembrane transport
NtRootD5_14750	COG1653	transport
NtRootD5_14760	COG1609	Transcriptional regulator
NtRootD5_14780	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NtRootD5_14790	COG0750	zinc metalloprotease
NtRootD5_14810	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NtRootD5_14840	COG1309	transcriptional regulator
NtRootD5_14880	COG0442	prolyl-tRNA aminoacylation
NtRootD5_14930	COG0779	Required for maturation of 30S ribosomal subunits
NtRootD5_14960	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NtRootD5_14960	COG0481	GTPase activity
NtRootD5_14970	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NtRootD5_14980	COG0590	tRNA wobble adenosine to inosine editing
NtRootD5_15000	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NtRootD5_15040	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NtRootD5_15050	COG1185	polyribonucleotide nucleotidyltransferase activity
NtRootD5_15060	COG0612	Peptidase, M16
NtRootD5_15100	COG0745	RESPONSE REGULATOR receiver
NtRootD5_15110	COG2205	protein histidine kinase activity
NtRootD5_15150	COG0521	Mo-molybdopterin cofactor biosynthetic process
NtRootD5_15170	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NtRootD5_15210	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NtRootD5_15220	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NtRootD5_15230	COG1674	ftsk spoiiie
NtRootD5_15250	COG1546	Belongs to the CinA family
NtRootD5_15250	COG1058	Belongs to the CinA family
NtRootD5_15260	COG1396	sequence-specific DNA binding
NtRootD5_15290	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NtRootD5_15300	COG2137	regulation of response to DNA damage stimulus
NtRootD5_15310	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NtRootD5_15320	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NtRootD5_15330	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NtRootD5_15340	COG2813	Specifically methylates the guanine in position
NtRootD5_15350	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NtRootD5_15370	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NtRootD5_15380	COG1388	LysM domain
NtRootD5_15400	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NtRootD5_15410	COG0131	Imidazoleglycerol-phosphate dehydratase
NtRootD5_15420	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NtRootD5_15440	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NtRootD5_15490	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NtRootD5_15500	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NtRootD5_15510	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NtRootD5_15520	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NtRootD5_15540	COG2814	Major facilitator Superfamily
NtRootD5_15610	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NtRootD5_15620	COG0072	phenylalanine-tRNA ligase activity
NtRootD5_15620	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NtRootD5_15630	COG3591	Belongs to the peptidase S1B family
NtRootD5_15700	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NtRootD5_15710	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NtRootD5_15720	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NtRootD5_15730	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NtRootD5_15740	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NtRootD5_15750	COG1438	arginine binding
NtRootD5_15760	COG0137	argininosuccinate synthase activity
NtRootD5_15770	COG0165	Argininosuccinate lyase
NtRootD5_15800	COG2094	Belongs to the DNA glycosylase MPG family
NtRootD5_15820	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NtRootD5_15850	COG0647	UMP catabolic process
NtRootD5_15880	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NtRootD5_15890	COG0497	DNA recombination
NtRootD5_15900	COG0504	CTP synthase activity
NtRootD5_15970	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NtRootD5_15980	COG2079	MmgE PrpD family protein
NtRootD5_16010	COG3290	protein histidine kinase activity
NtRootD5_16020	COG1301	dicarboxylic acid transport
NtRootD5_16040	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NtRootD5_16050	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NtRootD5_16080	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NtRootD5_16100	COG1160	GTP binding
NtRootD5_16120	COG2814	Major facilitator Superfamily
NtRootD5_16140	COG0509	glycine decarboxylation via glycine cleavage system
NtRootD5_16150	COG1716	ATPase activity
NtRootD5_16200	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NtRootD5_16220	COG1940	carbohydrate kinase activity
NtRootD5_16270	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
NtRootD5_16280	COG2815	serine threonine protein kinase
NtRootD5_16280	COG0515	serine threonine protein kinase
NtRootD5_16290	COG3942	CHAP domain
NtRootD5_16290	COG1388	LysM domain
NtRootD5_16320	COG0142	geranyltranstransferase activity
NtRootD5_16350	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NtRootD5_16370	COG2001	Belongs to the MraZ family
NtRootD5_16380	COG0275	rRNA processing
NtRootD5_16400	COG0768	penicillin binding
NtRootD5_16410	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NtRootD5_16430	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NtRootD5_16440	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NtRootD5_16460	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NtRootD5_16470	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NtRootD5_16490	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NtRootD5_16510	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NtRootD5_16520	COG1799	cell septum assembly
NtRootD5_16550	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NtRootD5_16600	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NtRootD5_16610	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NtRootD5_16620	COG1028	Short-chain dehydrogenase reductase Sdr
NtRootD5_16660	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NtRootD5_16670	COG0174	glutamine synthetase
NtRootD5_16680	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
NtRootD5_16750	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NtRootD5_16760	COG0321	lipoyl(octanoyl) transferase activity
NtRootD5_16770	COG0515	serine threonine protein kinase
NtRootD5_16770	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NtRootD5_16790	COG4946	Tricorn protease homolog
NtRootD5_16790	COG0793	Belongs to the peptidase S41A family
NtRootD5_16800	COG1764	response to oxidative stress
NtRootD5_16830	COG0508	dehydrogenase complex catalyzes the overall conversion of
NtRootD5_16840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NtRootD5_16850	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NtRootD5_16890	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NtRootD5_16950	COG1271	oxidase subunit
NtRootD5_16960	COG1294	oxidase, subunit
NtRootD5_16970	COG4988	ABC transporter
NtRootD5_17010	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NtRootD5_17020	COG0045	succinate-CoA ligase (ADP-forming) activity
NtRootD5_17020	COG1042	CoA-binding domain protein
NtRootD5_17020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NtRootD5_17050	COG1435	thymidine kinase activity
NtRootD5_17100	COG0756	dUTP diphosphatase activity
NtRootD5_17150	COG0569	domain protein
NtRootD5_17160	COG0531	amino acid
NtRootD5_17170	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NtRootD5_17180	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NtRootD5_17190	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NtRootD5_17230	COG0667	Aldo Keto reductase
NtRootD5_17240	COG1024	Enoyl-CoA hydratase
NtRootD5_17240	COG1250	3-hydroxyacyl-CoA dehydrogenase
NtRootD5_17250	COG0183	Belongs to the thiolase family
NtRootD5_17310	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NtRootD5_17340	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NtRootD5_17370	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NtRootD5_17380	COG3135	benzoate transporter
NtRootD5_17400	COG0531	amino acid
NtRootD5_17420	COG0242	peptide deformylase activity
NtRootD5_17430	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NtRootD5_17450	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NtRootD5_17490	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NtRootD5_17490	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NtRootD5_17510	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NtRootD5_17520	COG0140	phosphoribosyl-ATP diphosphatase activity
NtRootD5_17530	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NtRootD5_17540	COG0107	imidazoleglycerol-phosphate synthase activity
NtRootD5_17560	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NtRootD5_17600	COG0134	indole-3-glycerol-phosphate synthase activity
NtRootD5_17610	COG0133	tryptophan synthase activity
NtRootD5_17620	COG0159	tryptophan synthase activity
NtRootD5_17630	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NtRootD5_17640	COG0070	glutamate synthase
NtRootD5_17640	COG0069	glutamate synthase activity
NtRootD5_17640	COG0067	glutamate synthase
NtRootD5_17720	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NtRootD5_17730	COG0179	Fumarylacetoacetate (FAA) hydrolase
NtRootD5_17740	COG0145	ligase activity
NtRootD5_17780	COG1012	belongs to the aldehyde dehydrogenase family
NtRootD5_17790	COG0673	inositol 2-dehydrogenase activity
NtRootD5_17800	COG1028	Short-chain dehydrogenase reductase Sdr
NtRootD5_17810	COG0129	dihydroxy-acid dehydratase activity
NtRootD5_17820	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NtRootD5_17840	COG0673	inositol 2-dehydrogenase activity
NtRootD5_17860	COG1129	ABC transporter
NtRootD5_17870	COG1172	Belongs to the binding-protein-dependent transport system permease family
NtRootD5_17890	COG0277	FAD linked oxidase domain protein
NtRootD5_17890	COG0247	lactate metabolic process
NtRootD5_17950	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NtRootD5_17980	COG0800	Aldolase
NtRootD5_18000	COG1609	Transcriptional regulator
NtRootD5_18070	COG1028	Short-chain dehydrogenase reductase Sdr
NtRootD5_18090	COG0395	ABC-type sugar transport system, permease component
NtRootD5_18120	COG1760	l-serine dehydratase
NtRootD5_18150	COG2814	Major facilitator Superfamily
NtRootD5_18190	COG1733	regulation of RNA biosynthetic process
NtRootD5_18280	COG0443	Heat shock 70 kDa protein
NtRootD5_18290	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NtRootD5_18320	COG0542	response to heat
NtRootD5_18350	COG0747	negative chemotaxis
NtRootD5_18360	COG0601	transmembrane transport
NtRootD5_18370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NtRootD5_18380	COG0444	Belongs to the ABC transporter superfamily
NtRootD5_18390	COG4608	Belongs to the ABC transporter superfamily
NtRootD5_18410	COG1621	beta-fructofuranosidase activity
NtRootD5_18440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NtRootD5_18450	COG1028	Short-chain dehydrogenase reductase Sdr
NtRootD5_18470	COG0251	oxidation-reduction process
NtRootD5_18520	COG1802	Transcriptional regulator
NtRootD5_18540	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NtRootD5_18560	COG1126	abc transporter atp-binding protein
NtRootD5_18570	COG0765	amino acid transport
NtRootD5_18580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NtRootD5_18600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NtRootD5_18610	COG1012	belongs to the aldehyde dehydrogenase family
NtRootD5_18620	COG0473	3-isopropylmalate dehydrogenase activity
NtRootD5_18650	COG1064	alcohol dehydrogenase
NtRootD5_18660	COG0747	negative chemotaxis
NtRootD5_18680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NtRootD5_18690	COG4172	Belongs to the ABC transporter superfamily
NtRootD5_18700	COG1309	transcriptional regulator
NtRootD5_18720	COG0604	alcohol dehydrogenase
NtRootD5_18720	COG3321	synthase
NtRootD5_18880	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
NtRootD5_18940	COG1063	alcohol dehydrogenase
NtRootD5_18950	COG2217	Heavy metal translocating P-type atpase
NtRootD5_18970	COG0857	belongs to the CobB CobQ family
NtRootD5_18970	COG0280	phosphate acetyltransferase
NtRootD5_18980	COG0589	response to stress
NtRootD5_18990	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NtRootD5_19020	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NtRootD5_19030	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
NtRootD5_19050	COG0464	growth
NtRootD5_19180	COG1012	belongs to the aldehyde dehydrogenase family
NtRootD5_19230	COG2828	Protein conserved in bacteria
NtRootD5_19250	COG0673	inositol 2-dehydrogenase activity
NtRootD5_19270	COG0395	ABC-type sugar transport system, permease component
NtRootD5_19300	COG1609	Transcriptional regulator
NtRootD5_19320	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NtRootD5_19330	COG0318	PFAM AMP-dependent synthetase and ligase
NtRootD5_19340	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NtRootD5_19360	COG0475	glutathione-regulated potassium exporter activity
NtRootD5_19390	COG0028	Belongs to the TPP enzyme family
NtRootD5_19420	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NtRootD5_19520	COG1012	belongs to the aldehyde dehydrogenase family
NtRootD5_19530	COG2084	Dehydrogenase
NtRootD5_19540	COG1737	Transcriptional regulator
NtRootD5_19560	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NtRootD5_19580	COG3795	YCII-related domain
NtRootD5_19590	COG4941	Belongs to the sigma-70 factor family
NtRootD5_19620	COG1064	alcohol dehydrogenase
NtRootD5_19630	COG1643	Atp-dependent helicase
NtRootD5_19640	COG1228	amidohydrolase
NtRootD5_19710	COG0009	L-threonylcarbamoyladenylate synthase
NtRootD5_19750	COG2971	BadF BadG BcrA BcrD
NtRootD5_19770	COG1414	Transcriptional regulator
NtRootD5_19790	COG1053	succinate dehydrogenase
NtRootD5_19810	COG0477	Major facilitator Superfamily
NtRootD5_19840	COG3483	tryptophan 2,3-dioxygenase activity
NtRootD5_19910	COG2050	protein possibly involved in aromatic compounds catabolism
NtRootD5_19930	COG4552	Acetyltransferase involved in intracellular survival and related
NtRootD5_19950	COG0539	negative regulation of cytoplasmic translation
NtRootD5_19960	COG1739	Uncharacterized protein family UPF0029
NtRootD5_19970	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NtRootD5_19970	COG0237	dephospho-CoA kinase activity
NtRootD5_19980	COG0556	nucleotide-excision repair
NtRootD5_20000	COG0477	Major facilitator Superfamily
NtRootD5_20020	COG0456	acetyltransferase
NtRootD5_20030	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NtRootD5_20050	COG4106	trans-aconitate 2-methyltransferase activity
NtRootD5_20080	COG0546	phosphoglycolate phosphatase activity
NtRootD5_20100	COG0322	excinuclease ABC activity
NtRootD5_20110	COG1660	Displays ATPase and GTPase activities
NtRootD5_20130	COG1481	regulation of sporulation
NtRootD5_20140	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NtRootD5_20150	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NtRootD5_20160	COG0126	phosphoglycerate kinase activity
NtRootD5_20170	COG0149	triose-phosphate isomerase activity
NtRootD5_20180	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NtRootD5_20200	COG0363	glucosamine-6-phosphate deaminase activity
NtRootD5_20230	COG0166	Belongs to the GPI family
NtRootD5_20240	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NtRootD5_20260	COG0109	protoheme IX farnesyltransferase activity
NtRootD5_20300	COG0577	efflux transmembrane transporter activity
NtRootD5_20300	COG1136	(ABC) transporter
NtRootD5_20310	COG1612	heme a metabolic process
NtRootD5_20320	COG0842	Transport permease protein
NtRootD5_20330	COG1131	(ABC) transporter
NtRootD5_20360	COG0719	Fe-S assembly protein
NtRootD5_20380	COG0396	ATPase activity
NtRootD5_20390	COG2151	metal-sulfur cluster biosynthetic enzyme
NtRootD5_20410	COG0318	PFAM AMP-dependent synthetase and ligase
NtRootD5_20440	COG1122	ATPase activity
NtRootD5_20450	COG1268	BioY protein
NtRootD5_20460	COG0488	(ABC) transporter
NtRootD5_20510	COG1028	Short-chain dehydrogenase reductase Sdr
NtRootD5_20520	COG1028	Short-chain dehydrogenase reductase Sdr
NtRootD5_20530	COG1129	ABC transporter
NtRootD5_20560	COG0560	Phosphoserine phosphatase
NtRootD5_20560	COG3830	Belongs to the UPF0237 family
NtRootD5_20570	COG1119	ATPase activity
NtRootD5_20600	COG0254	rRNA binding
NtRootD5_20610	COG0095	Lipoate-protein ligase
NtRootD5_20650	COG2855	membrane
NtRootD5_20700	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NtRootD5_20720	COG0297	glycogen (starch) synthase activity
NtRootD5_20750	COG0183	Belongs to the thiolase family
NtRootD5_20780	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NtRootD5_20820	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NtRootD5_20830	COG0673	inositol 2-dehydrogenase activity
NtRootD5_20840	COG1088	dTDP-glucose 4,6-dehydratase activity
NtRootD5_20850	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NtRootD5_20980	COG1088	dTDP-glucose 4,6-dehydratase activity
NtRootD5_20990	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NtRootD5_21000	COG0667	Aldo Keto reductase
NtRootD5_21010	COG1968	undecaprenyl-diphosphatase activity
NtRootD5_21020	COG0215	cysteine-tRNA ligase activity
NtRootD5_21040	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NtRootD5_21050	COG1994	Peptidase M50
NtRootD5_21050	COG0517	IMP dehydrogenase activity
NtRootD5_21070	COG1222	aaa ATPase
NtRootD5_21080	COG4122	O-methyltransferase activity
NtRootD5_21100	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NtRootD5_21110	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NtRootD5_21120	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NtRootD5_21130	COG0545	Peptidyl-prolyl cis-trans isomerase
NtRootD5_21170	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NtRootD5_21180	COG0805	protein transport
NtRootD5_21190	COG4581	dead DEAH box helicase
NtRootD5_21200	COG1574	metal-dependent hydrolase with the TIM-barrel fold
NtRootD5_21210	COG1216	Glycosyl transferase, family 2
NtRootD5_21260	COG4946	Tricorn protease homolog
NtRootD5_21260	COG1506	peptidase
NtRootD5_21260	COG0823	Involved in the tonB-independent uptake of proteins
NtRootD5_21270	COG0242	peptide deformylase activity
NtRootD5_21310	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NtRootD5_21320	COG3424	synthase
NtRootD5_21330	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NtRootD5_21410	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NtRootD5_21420	COG1845	cytochrome c oxidase, subunit III
NtRootD5_21430	COG2010	Cytochrome c
NtRootD5_21440	COG0723	plastoquinol--plastocyanin reductase activity
NtRootD5_21450	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NtRootD5_21480	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NtRootD5_21500	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NtRootD5_21510	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NtRootD5_21550	COG0167	dihydroorotate dehydrogenase activity
NtRootD5_21590	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NtRootD5_21600	COG1381	Involved in DNA repair and RecF pathway recombination
NtRootD5_21610	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NtRootD5_21620	COG3590	peptidase
NtRootD5_21630	COG1316	TRANSCRIPTIONal
NtRootD5_21640	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NtRootD5_21660	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NtRootD5_21700	COG0484	heat shock protein binding
NtRootD5_21710	COG1420	regulation of RNA biosynthetic process
NtRootD5_21740	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NtRootD5_21750	COG0481	GTPase activity
NtRootD5_21770	COG0268	Binds directly to 16S ribosomal RNA
NtRootD5_21820	COG1307	EDD domain protein, DegV family
NtRootD5_21830	COG0495	leucyl-tRNA aminoacylation
NtRootD5_21840	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NtRootD5_21850	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NtRootD5_21860	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NtRootD5_21880	COG2390	Transcriptional regulator
NtRootD5_21890	COG0656	L-ascorbic acid biosynthetic process
NtRootD5_21910	COG0438	transferase activity, transferring glycosyl groups
NtRootD5_21930	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NtRootD5_21950	COG1758	RNA polymerase activity
NtRootD5_21960	COG0194	GDP metabolic process
NtRootD5_21980	COG0284	orotidine-5'-phosphate decarboxylase activity
NtRootD5_21990	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NtRootD5_22000	COG0505	Belongs to the CarA family
NtRootD5_22020	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NtRootD5_22030	COG0540	Belongs to the ATCase OTCase family
NtRootD5_22040	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NtRootD5_22070	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NtRootD5_22080	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NtRootD5_22100	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NtRootD5_22110	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NtRootD5_22120	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NtRootD5_22130	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NtRootD5_22160	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NtRootD5_22190	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NtRootD5_22230	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NtRootD5_22240	COG0124	histidyl-tRNA synthetase
NtRootD5_22260	COG1196	nuclear chromosome segregation
NtRootD5_22280	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NtRootD5_22290	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NtRootD5_22300	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NtRootD5_22320	COG2255	four-way junction helicase activity
NtRootD5_22330	COG0632	four-way junction helicase activity
NtRootD5_22340	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NtRootD5_22350	COG0217	transcriptional regulatory protein
NtRootD5_22360	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NtRootD5_22400	COG0339	signal peptide processing
NtRootD5_22410	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NtRootD5_22420	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NtRootD5_22440	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NtRootD5_22450	COG0587	DNA-directed DNA polymerase activity
NtRootD5_22500	COG2135	peptidase activity
NtRootD5_22530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NtRootD5_22590	COG0644	oxidoreductase
NtRootD5_22620	COG4804	nuclease activity
NtRootD5_22640	COG3842	ATPase activity
NtRootD5_22670	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NtRootD5_22680	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NtRootD5_22690	COG1780	Probably involved in ribonucleotide reductase function
NtRootD5_22710	COG0583	DNA-binding transcription factor activity
NtRootD5_22780	COG0714	Associated with various cellular activities
NtRootD5_22810	COG1175	transmembrane transport
NtRootD5_22840	COG2813	Specifically methylates the guanine in position
NtRootD5_22870	COG0799	negative regulation of ribosome biogenesis
NtRootD5_22890	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NtRootD5_22910	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NtRootD5_22920	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NtRootD5_22930	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NtRootD5_22940	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NtRootD5_22950	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NtRootD5_22960	COG0351	phosphomethylpyrimidine kinase
NtRootD5_22960	COG0352	thiamine-phosphate diphosphorylase activity
NtRootD5_22960	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NtRootD5_22970	COG1530	ribonuclease E activity
NtRootD5_22990	COG0105	UTP biosynthetic process
NtRootD5_23010	COG0285	dihydrofolate synthase activity
NtRootD5_23020	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NtRootD5_23050	COG0525	valine-tRNA ligase activity
NtRootD5_23060	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NtRootD5_23070	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NtRootD5_23080	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NtRootD5_23090	COG0740	serine-type endopeptidase activity
NtRootD5_23100	COG0740	serine-type endopeptidase activity
NtRootD5_23110	COG0544	peptidyl-prolyl cis-trans isomerase activity
NtRootD5_23180	COG0668	transmembrane transport
NtRootD5_23210	COG1946	Acyl-CoA thioesterase
NtRootD5_23260	COG0629	single-stranded DNA binding
NtRootD5_23300	COG0242	peptide deformylase activity
NtRootD5_23350	COG3022	response to hydroperoxide
NtRootD5_23370	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NtRootD5_23380	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NtRootD5_23400	COG1045	serine acetyltransferase
NtRootD5_23410	COG0300	oxidoreductase activity
NtRootD5_23420	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NtRootD5_23440	COG1063	alcohol dehydrogenase
NtRootD5_23450	COG1028	Short-chain dehydrogenase reductase Sdr
NtRootD5_23470	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NtRootD5_23490	COG0477	Major facilitator Superfamily
NtRootD5_23560	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
NtRootD5_23590	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NtRootD5_23600	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NtRootD5_23630	COG4974	Belongs to the 'phage' integrase family
NtRootD5_23660	COG0792	nuclease activity
NtRootD5_23680	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NtRootD5_23700	COG0681	Belongs to the peptidase S26 family
NtRootD5_23710	COG0335	large ribosomal subunit rRNA binding
NtRootD5_23720	COG0336	Belongs to the RNA methyltransferase TrmD family
NtRootD5_23730	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NtRootD5_23740	COG1837	Belongs to the UPF0109 family
NtRootD5_23750	COG0228	four-way junction DNA binding
NtRootD5_23770	COG2514	catechol 2,3-dioxygenase activity
NtRootD5_23820	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NtRootD5_23850	COG2814	Major facilitator Superfamily
NtRootD5_23920	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NtRootD5_23930	COG0571	ribonuclease III activity
NtRootD5_23940	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NtRootD5_23960	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NtRootD5_23990	COG0742	ribosomal rna small subunit methyltransferase
NtRootD5_24010	COG1461	Dihydroxyacetone kinase
NtRootD5_24040	COG1181	Belongs to the D-alanine--D-alanine ligase family
NtRootD5_24050	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NtRootD5_24070	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NtRootD5_24080	COG0066	3-isopropylmalate dehydratase activity
NtRootD5_24090	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NtRootD5_24100	COG1414	Transcriptional regulator
NtRootD5_24150	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NtRootD5_24160	COG0179	Fumarylacetoacetate (FAA) hydrolase
NtRootD5_24170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NtRootD5_24190	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NtRootD5_24200	COG0473	3-isopropylmalate dehydrogenase activity
NtRootD5_24210	COG4585	Histidine kinase
NtRootD5_24220	COG2197	response regulator
NtRootD5_24230	COG1136	(ABC) transporter
NtRootD5_24230	COG0577	efflux transmembrane transporter activity
NtRootD5_24260	COG0577	efflux transmembrane transporter activity
NtRootD5_24260	COG1136	(ABC) transporter
NtRootD5_24290	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NtRootD5_24300	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NtRootD5_24310	COG0440	acetolactate synthase activity
NtRootD5_24330	COG0129	dihydroxy-acid dehydratase activity
NtRootD5_24350	COG0088	Forms part of the polypeptide exit tunnel
NtRootD5_24390	COG0747	negative chemotaxis
NtRootD5_24400	COG0579	oxidoreductase
NtRootD5_24410	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NtRootD5_24420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NtRootD5_24440	COG1305	Transglutaminase-like
NtRootD5_24480	COG0179	Fumarylacetoacetate (FAA) hydrolase
NtRootD5_24500	COG1104	cysteine desulfurase activity
NtRootD5_24520	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NtRootD5_24530	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NtRootD5_24550	COG1522	sequence-specific DNA binding
NtRootD5_24560	COG1113	amino acid transport
NtRootD5_24580	COG0022	dehydrogenase e1 component
NtRootD5_24590	COG0508	dehydrogenase complex catalyzes the overall conversion of
NtRootD5_24630	COG0477	Major facilitator Superfamily
NtRootD5_24640	COG1414	Transcriptional regulator
NtRootD5_24700	COG1116	anion transmembrane transporter activity
NtRootD5_24710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NtRootD5_24740	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NtRootD5_24770	COG0419	ATPase involved in DNA repair
NtRootD5_24780	COG0420	3'-5' exonuclease activity
NtRootD5_24810	COG2149	membrane
NtRootD5_24860	COG1131	(ABC) transporter
NtRootD5_24890	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NtRootD5_24900	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NtRootD5_24910	COG1234	tRNA 3'-trailer cleavage
NtRootD5_24920	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NtRootD5_24940	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NtRootD5_24960	COG1335	isochorismatase
NtRootD5_24990	COG0363	glucosamine-6-phosphate deaminase activity
NtRootD5_25020	COG1902	pentaerythritol trinitrate reductase activity
NtRootD5_25080	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
NtRootD5_25090	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NtRootD5_25110	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NtRootD5_25120	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
NtRootD5_25140	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NtRootD5_25150	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NtRootD5_25160	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NtRootD5_25170	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NtRootD5_25180	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NtRootD5_25190	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NtRootD5_25200	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NtRootD5_25210	COG0356	it plays a direct role in the translocation of protons across the membrane
NtRootD5_25250	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NtRootD5_25280	COG0009	L-threonylcarbamoyladenylate synthase
NtRootD5_25290	COG2890	protein-(glutamine-N5) methyltransferase activity
NtRootD5_25300	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NtRootD5_25320	COG0083	homoserine kinase activity
NtRootD5_25330	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NtRootD5_25340	COG0460	homoserine dehydrogenase
NtRootD5_25350	COG0019	diaminopimelate decarboxylase activity
NtRootD5_25360	COG0018	arginyl-trna synthetase
NtRootD5_25400	COG1017	nitric oxide dioxygenase activity
NtRootD5_25400	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NtRootD5_25460	COG1643	Atp-dependent helicase
NtRootD5_25470	COG0537	adenosine 5'-monophosphoramidase activity
NtRootD5_25480	COG1064	alcohol dehydrogenase
NtRootD5_25520	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NtRootD5_25550	COG1121	(ABC) transporter
NtRootD5_25560	COG0803	Belongs to the bacterial solute-binding protein 9 family
NtRootD5_25580	COG1253	flavin adenine dinucleotide binding
NtRootD5_25590	COG0508	dehydrogenase complex catalyzes the overall conversion of
NtRootD5_25590	COG0567	Dehydrogenase, E1 component
NtRootD5_25660	COG1595	DNA-templated transcription, initiation
NtRootD5_25680	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NtRootD5_25700	COG0483	inositol monophosphate 1-phosphatase activity
NtRootD5_25710	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NtRootD5_25770	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NtRootD5_25790	COG2177	Part of the ABC transporter FtsEX involved in
NtRootD5_25800	COG2884	Cell division ATP-binding protein ftsE
NtRootD5_25810	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NtRootD5_25940	COG1216	Glycosyl transferase, family 2
NtRootD5_25990	COG1216	Glycosyl transferase, family 2
NtRootD5_26030	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NtRootD5_26060	COG0433	COG0433 Predicted ATPase
NtRootD5_26060	COG1674	ftsk spoiiie
NtRootD5_26100	COG2902	Dehydrogenase
NtRootD5_26170	COG0653	protein targeting
NtRootD5_26180	COG3214	Protein conserved in bacteria
NtRootD5_26190	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NtRootD5_26220	COG5401	PFAM Sporulation and spore germination
NtRootD5_26230	COG5002	protein histidine kinase activity
NtRootD5_26280	COG0714	Associated with various cellular activities
NtRootD5_26350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NtRootD5_26360	COG0601	transmembrane transport
NtRootD5_26400	COG0482	sulfurtransferase activity
NtRootD5_26410	COG1053	succinate dehydrogenase
NtRootD5_26440	COG0446	pyridine nucleotide-disulphide oxidoreductase
NtRootD5_26440	COG1902	pentaerythritol trinitrate reductase activity
NtRootD5_26450	COG0673	inositol 2-dehydrogenase activity
NtRootD5_26470	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NtRootD5_26480	COG0477	Major facilitator Superfamily
NtRootD5_26490	COG0583	DNA-binding transcription factor activity
NtRootD5_26530	COG0484	heat shock protein binding
NtRootD5_26540	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NtRootD5_26550	COG1595	DNA-templated transcription, initiation
NtRootD5_26580	COG3265	gluconokinase activity
NtRootD5_26590	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NtRootD5_26600	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
NtRootD5_26610	COG2086	electron transfer activity
NtRootD5_26620	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NtRootD5_26650	COG1842	Phage shock protein A
NtRootD5_26670	COG1615	UPF0182 protein
NtRootD5_26680	COG3480	Lon protease (S16) C-terminal proteolytic domain
NtRootD5_26720	COG2816	NAD+ diphosphatase activity
NtRootD5_26780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NtRootD5_26790	COG0765	amino acid transport
NtRootD5_26800	COG1126	abc transporter atp-binding protein
NtRootD5_26830	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NtRootD5_26850	COG0113	porphobilinogen synthase activity
NtRootD5_26870	COG0181	hydroxymethylbilane synthase activity
NtRootD5_26880	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NtRootD5_26890	COG3253	May function as heme-dependent peroxidase
NtRootD5_26900	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NtRootD5_26910	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NtRootD5_26920	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NtRootD5_26950	COG1309	transcriptional regulator
NtRootD5_27010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NtRootD5_27010	COG2022	thiamine diphosphate biosynthetic process
NtRootD5_27020	COG0352	thiamine-phosphate diphosphorylase activity
NtRootD5_27040	COG2267	carboxylic ester hydrolase activity
NtRootD5_27060	COG0513	Belongs to the DEAD box helicase family
NtRootD5_27080	COG2095	MarC family integral membrane protein
NtRootD5_27100	COG0006	proline dipeptidase activity
NtRootD5_27120	COG2239	Acts as a magnesium transporter
NtRootD5_27150	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NtRootD5_27170	COG1595	DNA-templated transcription, initiation
NtRootD5_27230	COG1126	abc transporter atp-binding protein
NtRootD5_27250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NtRootD5_27260	COG0765	amino acid transport
NtRootD5_27270	COG0765	amino acid transport
NtRootD5_27280	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NtRootD5_27290	COG2171	N-acyltransferase activity
NtRootD5_27320	COG3226	Transcriptional regulator
NtRootD5_27330	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NtRootD5_27390	COG1217	gtp-binding protein TYPA
NtRootD5_27420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NtRootD5_27440	COG4166	transmembrane transport
NtRootD5_27460	COG0012	GTP binding
NtRootD5_27470	COG1322	Protein conserved in bacteria
NtRootD5_27480	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NtRootD5_27500	COG1570	exodeoxyribonuclease VII activity
NtRootD5_27510	COG1722	exodeoxyribonuclease VII activity
NtRootD5_27520	COG2326	polyphosphate kinase activity
NtRootD5_27560	COG1174	glycine betaine transport
NtRootD5_27580	COG1162	GTPase activity
NtRootD5_27630	COG2971	BadF BadG BcrA BcrD
NtRootD5_27650	COG0583	DNA-binding transcription factor activity
NtRootD5_27660	COG2814	Major facilitator Superfamily
NtRootD5_27670	COG3548	integral membrane protein
NtRootD5_27720	COG0598	Magnesium transport protein CorA
NtRootD5_27740	COG1528	Iron-storage protein
NtRootD5_27750	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NtRootD5_27760	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NtRootD5_27780	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NtRootD5_27790	COG1695	Transcriptional regulator
NtRootD5_27990	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NtRootD5_28100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NtRootD5_28110	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NtRootD5_28120	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NtRootD5_28160	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NtRootD5_28160	COG0519	Catalyzes the synthesis of GMP from XMP
NtRootD5_28200	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NtRootD5_28210	COG0516	GMP reductase activity
NtRootD5_28250	COG1132	(ABC) transporter
NtRootD5_28290	COG0459	protein refolding
NtRootD5_28300	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NtRootD5_28330	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NtRootD5_28340	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NtRootD5_28360	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NtRootD5_28370	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NtRootD5_28400	COG0802	atpase or kinase
NtRootD5_28410	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NtRootD5_28450	COG0438	transferase activity, transferring glycosyl groups
NtRootD5_28460	COG2759	Belongs to the formate--tetrahydrofolate ligase family
NtRootD5_28480	COG0667	Aldo Keto reductase
NtRootD5_28530	COG0736	holo-[acyl-carrier-protein] synthase activity
NtRootD5_28550	COG1072	(Pantothenic acid kinase))
NtRootD5_28570	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NtRootD5_28580	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NtRootD5_28590	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NtRootD5_28630	COG2894	cell division
NtRootD5_28690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NtRootD5_28710	COG0101	tRNA pseudouridine synthase activity
NtRootD5_28720	COG0203	ribosomal protein L17
NtRootD5_28730	COG0202	RNA polymerase activity
NtRootD5_28740	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NtRootD5_28750	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NtRootD5_28760	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NtRootD5_28770	COG3191	aminopeptidase activity
NtRootD5_28830	COG0318	PFAM AMP-dependent synthetase and ligase
NtRootD5_28840	COG2124	cytochrome p450
NtRootD5_28850	COG1216	Glycosyl transferase, family 2
NtRootD5_28860	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NtRootD5_28870	COG0563	adenylate kinase activity
NtRootD5_28890	COG0200	Binds to the 23S rRNA
NtRootD5_28900	COG1841	ribosomal large subunit assembly
NtRootD5_28910	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NtRootD5_28930	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NtRootD5_28940	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NtRootD5_28950	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NtRootD5_28960	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NtRootD5_28970	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NtRootD5_28980	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NtRootD5_28990	COG0255	Belongs to the universal ribosomal protein uL29 family
NtRootD5_29000	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NtRootD5_29010	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NtRootD5_29020	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NtRootD5_29030	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NtRootD5_29040	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NtRootD5_29050	COG0089	rRNA binding
NtRootD5_29060	COG0088	Forms part of the polypeptide exit tunnel
NtRootD5_29070	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NtRootD5_29080	COG0051	transcription antitermination factor activity, RNA binding
NtRootD5_29120	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NtRootD5_29130	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NtRootD5_29140	COG0049	tRNA binding
NtRootD5_29150	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NtRootD5_29160	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NtRootD5_29170	COG0085	RNA polymerase activity
NtRootD5_29180	COG0183	Belongs to the thiolase family
NtRootD5_29190	COG0442	prolyl-tRNA aminoacylation
NtRootD5_29200	COG0222	ribosome binding
NtRootD5_29210	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NtRootD5_29250	COG0081	regulation of translation
NtRootD5_29260	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NtRootD5_29290	COG0436	Aminotransferase
NtRootD5_29300	COG2197	response regulator
NtRootD5_29420	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NtRootD5_29440	COG3485	protocatechuate 3,4-dioxygenase
NtRootD5_29470	COG0745	RESPONSE REGULATOR receiver
NtRootD5_29480	COG0456	acetyltransferase
NtRootD5_29490	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NtRootD5_29500	COG0406	alpha-ribazole phosphatase activity
NtRootD5_29500	COG0494	nUDIX hydrolase
NtRootD5_29540	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NtRootD5_29550	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NtRootD5_29570	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NtRootD5_29610	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NtRootD5_29620	COG0738	Major facilitator superfamily
NtRootD5_29640	COG2030	dehydratase
NtRootD5_29700	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NtRootD5_29720	COG4989	oxidoreductase activity
NtRootD5_29730	COG0366	Alpha amylase catalytic
NtRootD5_29740	COG0395	ABC-type sugar transport system, permease component
NtRootD5_29750	COG1175	transmembrane transport
NtRootD5_29780	COG1940	carbohydrate kinase activity
NtRootD5_29810	COG1376	ErfK ybiS ycfS ynhG family protein
NtRootD5_29870	COG0754	glutathionylspermidine amidase activity
NtRootD5_29890	COG5650	phosphatidylinositol metabolic process
NtRootD5_29930	COG1175	transmembrane transport
NtRootD5_29940	COG0395	ABC-type sugar transport system, permease component
NtRootD5_29990	COG5650	phosphatidylinositol metabolic process
NtRootD5_30050	COG0318	PFAM AMP-dependent synthetase and ligase
NtRootD5_30070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NtRootD5_30080	COG1309	transcriptional regulator
NtRootD5_30090	COG1131	(ABC) transporter
NtRootD5_30130	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NtRootD5_30150	COG1666	GTP binding
NtRootD5_30160	COG0672	)-iron permease
NtRootD5_30180	COG2837	iron assimilation
NtRootD5_30210	COG0501	Belongs to the peptidase M48B family
NtRootD5_30270	COG0531	amino acid
NtRootD5_30370	COG0395	ABC-type sugar transport system, permease component
NtRootD5_30380	COG4209	transmembrane transport
NtRootD5_30400	COG1609	Transcriptional regulator
NtRootD5_30440	COG1012	belongs to the aldehyde dehydrogenase family
NtRootD5_30450	COG3835	regulator
NtRootD5_30460	COG2807	transmembrane transport
NtRootD5_30470	COG2186	Transcriptional regulator
NtRootD5_30480	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NtRootD5_30480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NtRootD5_30500	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NtRootD5_30500	COG1648	precorrin-2 dehydrogenase activity
NtRootD5_30510	COG2066	Belongs to the glutaminase family
NtRootD5_30520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NtRootD5_30570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NtRootD5_30580	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NtRootD5_30600	COG2040	homocysteine
NtRootD5_30610	COG2895	sulfate adenylyltransferase (ATP) activity
NtRootD5_30630	COG0175	sulfate reduction
NtRootD5_30660	COG2860	membrane
NtRootD5_30690	COG0142	geranyltranstransferase activity
NtRootD5_30710	COG2226	methyltransferase
NtRootD5_30720	COG1169	isochorismate synthase
NtRootD5_30730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NtRootD5_30740	COG0765	amino acid transport
NtRootD5_30770	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NtRootD5_30790	COG4948	Mandelate Racemase Muconate Lactonizing
NtRootD5_30850	COG0395	ABC-type sugar transport system, permease component
NtRootD5_30860	COG1175	transmembrane transport
NtRootD5_30950	COG1404	Belongs to the peptidase S8 family
NtRootD5_31010	COG0508	dehydrogenase complex catalyzes the overall conversion of
NtRootD5_31020	COG0022	dehydrogenase e1 component
NtRootD5_31060	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NtRootD5_31080	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NtRootD5_31090	COG1088	dTDP-glucose 4,6-dehydratase activity
NtRootD5_31110	COG0489	protein tyrosine kinase activity
NtRootD5_31190	COG0438	transferase activity, transferring glycosyl groups
NtRootD5_31190	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NtRootD5_31210	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NtRootD5_31290	COG2267	carboxylic ester hydrolase activity
NtRootD5_31310	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NtRootD5_31320	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NtRootD5_31330	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NtRootD5_31340	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
NtRootD5_31470	COG1846	Transcriptional regulator
NtRootD5_31480	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
NtRootD5_31520	COG1063	alcohol dehydrogenase
NtRootD5_31550	COG0667	Aldo Keto reductase
NtRootD5_31610	COG1024	Enoyl-CoA hydratase
NtRootD5_31620	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NtRootD5_31630	COG2151	metal-sulfur cluster biosynthetic enzyme
NtRootD5_31640	COG3396	Phenylacetate-CoA oxygenase
NtRootD5_31650	COG3460	Phenylacetate-CoA oxygenase
NtRootD5_31660	COG3396	Phenylacetate-CoA oxygenase
NtRootD5_31670	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NtRootD5_31680	COG1388	LysM domain
NtRootD5_31680	COG3942	CHAP domain
NtRootD5_31700	COG3706	GGDEF domain
NtRootD5_31730	COG0438	transferase activity, transferring glycosyl groups
NtRootD5_31750	COG0438	transferase activity, transferring glycosyl groups
NtRootD5_31780	COG2226	methyltransferase
NtRootD5_31800	COG5002	protein histidine kinase activity
NtRootD5_31850	COG2050	protein possibly involved in aromatic compounds catabolism
NtRootD5_31880	COG1012	belongs to the aldehyde dehydrogenase family
NtRootD5_31880	COG2030	dehydratase
NtRootD5_31910	COG1250	3-hydroxyacyl-CoA dehydrogenase
NtRootD5_31920	COG1024	Enoyl-CoA hydratase
NtRootD5_31980	COG1266	CAAX protease self-immunity
NtRootD5_32000	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NtRootD5_32100	COG0443	Heat shock 70 kDa protein
NtRootD5_32110	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NtRootD5_32130	COG0785	Cytochrome C biogenesis protein
NtRootD5_32150	COG0406	alpha-ribazole phosphatase activity
NtRootD5_32210	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NtRootD5_32260	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NtRootD5_32270	COG3458	cephalosporin-C deacetylase activity
NtRootD5_32290	COG2814	Major facilitator Superfamily
NtRootD5_32310	COG0395	ABC-type sugar transport system, permease component
NtRootD5_32320	COG1175	transmembrane transport
NtRootD5_32360	COG0395	ABC-type sugar transport system, permease component
NtRootD5_32370	COG1175	transmembrane transport
NtRootD5_32390	COG0673	inositol 2-dehydrogenase activity
NtRootD5_32420	COG4948	Mandelate Racemase Muconate Lactonizing
NtRootD5_32430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NtRootD5_32450	COG0673	inositol 2-dehydrogenase activity
NtRootD5_32460	COG1609	Transcriptional regulator
NtRootD5_32490	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NtRootD5_32500	COG0640	Transcriptional regulator
NtRootD5_32530	COG0123	including yeast histone deacetylase and acetoin utilization protein
NtRootD5_32540	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NtRootD5_32550	COG0569	domain protein
NtRootD5_32560	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NtRootD5_32570	COG1082	Xylose isomerase domain protein TIM barrel
NtRootD5_32580	COG0248	Ppx GppA phosphatase
NtRootD5_32600	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NtRootD5_32600	COG1754	DNA topoisomerase type I activity
NtRootD5_32650	COG1054	Belongs to the UPF0176 family
NtRootD5_32670	COG1111	helicase
NtRootD5_32670	COG1205	dead DEAH box helicase
NtRootD5_32810	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NtRootD5_32820	COG1349	DNA-binding transcription factor activity
NtRootD5_32850	COG2826	transposase and inactivated derivatives, IS30 family
NtRootD5_32860	COG1609	Transcriptional regulator
NtRootD5_32880	COG1175	transmembrane transport
NtRootD5_32890	COG0395	ABC-type sugar transport system, permease component
NtRootD5_32980	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NtRootD5_32990	COG1408	metallophosphoesterase
NtRootD5_33000	COG1132	(ABC) transporter
NtRootD5_33010	COG1132	(ABC) transporter
NtRootD5_33050	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NtRootD5_33060	COG0151	Belongs to the GarS family
NtRootD5_33090	COG1301	dicarboxylic acid transport
NtRootD5_33110	COG1028	Short-chain dehydrogenase reductase Sdr
NtRootD5_33130	COG1953	Uracil, thiamine, allantoin
NtRootD5_33140	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
NtRootD5_33170	COG0454	-acetyltransferase
NtRootD5_33180	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NtRootD5_33200	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NtRootD5_33200	COG3608	succinylglutamate desuccinylase aspartoacylase
NtRootD5_33210	COG2252	PERMEase
NtRootD5_33220	COG0590	tRNA wobble adenosine to inosine editing
NtRootD5_33290	COG2233	PERMEase
NtRootD5_33300	COG1414	Transcriptional regulator
NtRootD5_33320	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NtRootD5_33340	COG3257	ureidoglycine aminohydrolase activity
NtRootD5_33370	COG0395	ABC-type sugar transport system, permease component
NtRootD5_33390	COG1653	transport
NtRootD5_33410	COG3119	arylsulfatase activity
NtRootD5_33420	COG1609	Transcriptional regulator
NtRootD5_33430	COG5492	domain, Protein
NtRootD5_33440	COG3654	unkown
NtRootD5_33460	COG2318	DinB family
NtRootD5_33520	COG2271	Major facilitator Superfamily
NtRootD5_33550	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NtRootD5_33550	COG4499	WXG100 protein secretion system (Wss), protein YukC
NtRootD5_33570	COG2814	Major facilitator Superfamily
NtRootD5_33600	COG0659	secondary active sulfate transmembrane transporter activity
NtRootD5_33680	COG0563	adenylate kinase activity
NtRootD5_33700	COG0477	Major facilitator Superfamily
NtRootD5_33720	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NtRootD5_33740	COG3401	FG-GAP repeat protein
NtRootD5_33750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NtRootD5_33790	COG2011	ABC-type metal ion transport system permease component
NtRootD5_33800	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NtRootD5_33810	COG1464	Belongs to the NlpA lipoprotein family
NtRootD5_33820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NtRootD5_33910	COG2267	carboxylic ester hydrolase activity
NtRootD5_33970	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NtRootD5_33980	COG1733	regulation of RNA biosynthetic process
NtRootD5_33990	COG3025	triphosphatase activity
NtRootD5_33990	COG5607	PFAM CHAD domain containing protein
NtRootD5_34070	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NtRootD5_34150	COG0405	Gamma-glutamyltransferase
NtRootD5_34260	COG0673	inositol 2-dehydrogenase activity
NtRootD5_34280	COG0673	inositol 2-dehydrogenase activity
NtRootD5_34310	COG1653	transport
NtRootD5_34320	COG1609	Transcriptional regulator
NtRootD5_34390	COG3622	Belongs to the hyi family
NtRootD5_34400	COG2084	Dehydrogenase
NtRootD5_34410	COG3960	tartronate-semialdehyde synthase activity
NtRootD5_34420	COG1929	Belongs to the glycerate kinase type-1 family
NtRootD5_34430	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NtRootD5_34440	COG0745	RESPONSE REGULATOR receiver
NtRootD5_34470	COG0745	RESPONSE REGULATOR receiver
NtRootD5_34480	COG1215	transferase activity, transferring glycosyl groups
NtRootD5_34490	COG1366	Belongs to the anti-sigma-factor antagonist family
NtRootD5_34510	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NtRootD5_34550	COG2814	Major facilitator Superfamily
NtRootD5_34570	COG0671	phosphoesterase, PA-phosphatase related
NtRootD5_34600	COG2826	transposase and inactivated derivatives, IS30 family
NtRootD5_34630	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NtRootD5_34670	COG0542	response to heat
NtRootD5_34720	COG3585	molybdate ion transport
NtRootD5_34730	COG4585	Histidine kinase
NtRootD5_34740	COG2197	response regulator
NtRootD5_34800	COG3304	Inner membrane component domain
NtRootD5_34810	COG0135	phosphoribosylanthranilate isomerase activity
NtRootD5_34850	COG0667	Aldo Keto reductase
NtRootD5_34880	COG2814	Major facilitator Superfamily
NtRootD5_34900	COG2813	Specifically methylates the guanine in position
NtRootD5_34920	COG1473	amidohydrolase
NtRootD5_34930	COG0477	Major facilitator Superfamily
NtRootD5_34940	COG2807	transmembrane transport
NtRootD5_34970	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NtRootD5_35080	COG2188	Transcriptional regulator
NtRootD5_35150	COG1012	belongs to the aldehyde dehydrogenase family
NtRootD5_35180	COG0596	Alpha beta hydrolase
NtRootD5_35180	COG2945	thiolester hydrolase activity
NtRootD5_35190	COG1028	Short-chain dehydrogenase reductase Sdr
NtRootD5_35260	COG1846	Transcriptional regulator
NtRootD5_35270	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
NtRootD5_35280	COG0789	Transcriptional regulator
NtRootD5_35290	COG0484	heat shock protein binding
NtRootD5_35300	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NtRootD5_35310	COG0443	Heat shock 70 kDa protein
NtRootD5_35320	COG3739	integral membrane protein
NtRootD5_35370	COG1917	Cupin 2, conserved barrel domain protein
NtRootD5_35370	COG4977	sequence-specific DNA binding
NtRootD5_35400	COG3540	Alkaline phosphatase
NtRootD5_35410	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
NtRootD5_35480	COG0531	amino acid
NtRootD5_35510	COG3226	Transcriptional regulator
NtRootD5_35520	COG1280	lysine exporter protein (LysE YggA)
NtRootD5_35570	COG0492	ferredoxin-NADP+ reductase activity
NtRootD5_35580	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NtRootD5_35590	COG0798	PFAM Bile acid sodium symporter
NtRootD5_35600	COG0640	Transcriptional regulator
NtRootD5_35620	COG2409	Drug exporters of the RND superfamily
NtRootD5_35650	COG3795	YCII-related domain
NtRootD5_35670	COG4941	Belongs to the sigma-70 factor family
NtRootD5_35710	COG1280	lysine exporter protein (LysE YggA)
NtRootD5_35730	COG1609	Transcriptional regulator
NtRootD5_35740	COG1957	nucleoside hydrolase
NtRootD5_35750	COG0477	Major facilitator Superfamily
NtRootD5_35760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NtRootD5_35790	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NtRootD5_35810	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NtRootD5_35830	COG0833	amino acid
NtRootD5_35840	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NtRootD5_35860	COG2986	histidine ammonia-lyase
NtRootD5_35920	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NtRootD5_35940	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NtRootD5_35950	COG1132	(ABC) transporter
NtRootD5_35950	COG2375	cellular response to nickel ion
NtRootD5_35990	COG1122	ATPase activity
NtRootD5_36000	COG4721	ABC-type cobalt transport system, permease component
NtRootD5_36030	COG1320	monovalent cation:proton antiporter activity
NtRootD5_36040	COG2212	antiporter activity
NtRootD5_36060	COG0651	ATP synthesis coupled electron transport
NtRootD5_36070	COG1006	Multisubunit Na H antiporter MnhC subunit
NtRootD5_36080	COG2111	Na H antiporter
NtRootD5_36080	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NtRootD5_36110	COG0475	glutathione-regulated potassium exporter activity
NtRootD5_36130	COG0717	Belongs to the dCTP deaminase family
NtRootD5_36160	COG1876	peptidase activity
NtRootD5_36170	COG0686	Belongs to the AlaDH PNT family
NtRootD5_36190	COG0583	DNA-binding transcription factor activity
NtRootD5_36210	COG0640	Transcriptional regulator
NtRootD5_36250	COG0657	acetylesterase activity
NtRootD5_36250	COG2755	lipolytic protein G-D-S-L family
NtRootD5_36260	COG1609	Transcriptional regulator
NtRootD5_36270	COG0673	inositol 2-dehydrogenase activity
NtRootD5_36330	COG2115	Belongs to the xylose isomerase family
NtRootD5_36340	COG1070	Carbohydrate kinase
NtRootD5_36350	COG1609	Transcriptional regulator
NtRootD5_36380	COG2160	L-arabinose isomerase activity
NtRootD5_36390	COG2017	converts alpha-aldose to the beta-anomer
NtRootD5_36410	COG2211	Major facilitator Superfamily
NtRootD5_36420	COG1846	Transcriptional regulator
NtRootD5_36420	COG1940	carbohydrate kinase activity
NtRootD5_36440	COG0765	amino acid transport
NtRootD5_36450	COG0765	amino acid transport
NtRootD5_36480	COG0251	oxidation-reduction process
NtRootD5_36510	COG0583	DNA-binding transcription factor activity
NtRootD5_36540	COG1609	Transcriptional regulator
NtRootD5_36550	COG3254	rhamnose metabolic process
NtRootD5_36570	COG3347	Dehydrogenase
NtRootD5_36570	COG1028	Short-chain dehydrogenase reductase Sdr
NtRootD5_36580	COG1070	Carbohydrate kinase
NtRootD5_36590	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NtRootD5_36610	COG3387	PFAM Glycoside hydrolase 15-related
NtRootD5_36620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NtRootD5_36630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NtRootD5_36640	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NtRootD5_36680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NtRootD5_36690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NtRootD5_36710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NtRootD5_36730	COG1126	abc transporter atp-binding protein
NtRootD5_36740	COG0765	amino acid transport
NtRootD5_36770	COG0433	COG0433 Predicted ATPase
NtRootD5_36800	COG3336	cytochrome c oxidase
NtRootD5_36810	COG0776	regulation of translation
NtRootD5_36860	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NtRootD5_36870	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NtRootD5_36880	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NtRootD5_36890	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NtRootD5_36890	COG1017	nitric oxide dioxygenase activity
NtRootD5_36980	COG1120	ATPase activity
NtRootD5_36990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NtRootD5_37000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NtRootD5_37080	COG3012	SEC-C Motif Domain Protein
NtRootD5_37110	COG0667	Aldo Keto reductase
NtRootD5_37190	COG2186	Transcriptional regulator
NtRootD5_37210	COG1027	Aspartate ammonia-lyase
NtRootD5_37260	COG3254	rhamnose metabolic process
NtRootD5_37280	COG4948	Mandelate Racemase Muconate Lactonizing
NtRootD5_37300	COG1028	Short-chain dehydrogenase reductase Sdr
NtRootD5_37320	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NtRootD5_37350	COG4221	oxidoreductase activity
NtRootD5_37370	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NtRootD5_37380	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NtRootD5_37420	COG1522	sequence-specific DNA binding
NtRootD5_37430	COG1280	lysine exporter protein (LysE YggA)
NtRootD5_37450	COG0640	Transcriptional regulator
NtRootD5_37490	COG2826	transposase and inactivated derivatives, IS30 family
NtRootD5_37510	COG2826	transposase and inactivated derivatives, IS30 family
NtRootD5_37520	COG1414	Transcriptional regulator
NtRootD5_37540	COG0477	Major facilitator Superfamily
NtRootD5_37560	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NtRootD5_37610	COG1760	l-serine dehydratase
NtRootD5_37660	COG2826	transposase and inactivated derivatives, IS30 family
NtRootD5_37680	COG0281	malic enzyme
NtRootD5_37690	COG1309	transcriptional regulator
NtRootD5_37730	COG2211	Major facilitator Superfamily
NtRootD5_37740	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NtRootD5_37750	COG0477	Major facilitator Superfamily
NtRootD5_37760	COG0477	Major facilitator Superfamily
NtRootD5_37770	COG2814	Major facilitator Superfamily
NtRootD5_37840	COG1113	amino acid transport
NtRootD5_37850	COG0246	Mannitol dehydrogenase
NtRootD5_37860	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NtRootD5_37860	COG2213	PTS system mannitol-specific
NtRootD5_37880	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NtRootD5_37920	COG0596	Alpha beta hydrolase
NtRootD5_37940	COG1793	dna ligase
NtRootD5_37990	COG0686	Belongs to the AlaDH PNT family
NtRootD5_38030	COG0673	inositol 2-dehydrogenase activity
NtRootD5_38080	COG1309	transcriptional regulator
NtRootD5_38090	COG0431	NADPH-dependent FMN reductase
NtRootD5_38140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NtRootD5_38180	COG0508	dehydrogenase complex catalyzes the overall conversion of
NtRootD5_38190	COG0022	dehydrogenase e1 component
NtRootD5_38210	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NtRootD5_38220	COG1950	PFAM Membrane protein of
NtRootD5_38250	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NtRootD5_38280	COG1607	acyl-coa hydrolase
NtRootD5_38290	COG4221	oxidoreductase activity
NtRootD5_38300	COG0477	Major facilitator Superfamily
NtRootD5_38310	COG1984	allophanate hydrolase subunit 2
NtRootD5_38320	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NtRootD5_38330	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NtRootD5_38340	COG0583	DNA-binding transcription factor activity
NtRootD5_38360	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NtRootD5_38370	COG0436	Aminotransferase
NtRootD5_38420	COG3971	2-oxopent-4-enoate hydratase activity
NtRootD5_38450	COG1802	Transcriptional regulator
NtRootD5_38460	COG0179	Fumarylacetoacetate (FAA) hydrolase
NtRootD5_38520	COG2207	Transcriptional regulator
NtRootD5_38520	COG3708	Transcriptional regulator
NtRootD5_38530	COG1028	Short-chain dehydrogenase reductase Sdr
NtRootD5_38690	COG2205	protein histidine kinase activity
NtRootD5_38700	COG2815	serine threonine protein kinase
NtRootD5_38700	COG0515	serine threonine protein kinase
NtRootD5_38740	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NtRootD5_38750	COG3387	PFAM Glycoside hydrolase 15-related
NtRootD5_38770	COG0076	glutamate decarboxylase activity
NtRootD5_38790	COG1011	Hydrolase
NtRootD5_38830	COG1414	Transcriptional regulator
NtRootD5_38840	COG2814	Major facilitator Superfamily
NtRootD5_38930	COG1846	Transcriptional regulator
NtRootD5_38990	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NtRootD5_39000	COG1760	l-serine dehydratase
NtRootD5_39010	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NtRootD5_39020	COG0509	glycine decarboxylation via glycine cleavage system
NtRootD5_39030	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NtRootD5_39040	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NtRootD5_39040	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NtRootD5_39060	COG2271	Major facilitator Superfamily
NtRootD5_39080	COG1970	mechanosensitive ion channel activity
NtRootD5_39390	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NtRootD5_39410	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NtRootD5_39460	COG2826	transposase and inactivated derivatives, IS30 family
NtRootD5_39470	COG2814	Major facilitator Superfamily
NtRootD5_39490	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NtRootD5_39520	COG0179	Fumarylacetoacetate (FAA) hydrolase
NtRootD5_39530	COG0251	oxidation-reduction process
NtRootD5_39550	COG1414	Transcriptional regulator
NtRootD5_39560	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NtRootD5_39580	COG0183	Belongs to the thiolase family
NtRootD5_39590	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NtRootD5_39600	COG2267	carboxylic ester hydrolase activity
NtRootD5_39630	COG3485	protocatechuate 3,4-dioxygenase
NtRootD5_39640	COG3185	4-Hydroxyphenylpyruvate dioxygenase
NtRootD5_39640	COG1082	Xylose isomerase domain protein TIM barrel
NtRootD5_39650	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NtRootD5_39660	COG1414	Transcriptional regulator
NtRootD5_39700	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NtRootD5_39720	COG3706	GGDEF domain
NtRootD5_39790	COG0583	DNA-binding transcription factor activity
NtRootD5_39860	COG2610	gluconate transmembrane transporter activity
NtRootD5_39870	COG0800	Aldolase
NtRootD5_39880	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
NtRootD5_39910	COG1414	Transcriptional regulator
NtRootD5_40010	COG2326	polyphosphate kinase activity
NtRootD5_40030	COG1737	Transcriptional regulator
NtRootD5_40040	COG3876	Protein conserved in bacteria
NtRootD5_40050	COG1472	Belongs to the glycosyl hydrolase 3 family
NtRootD5_40090	COG1937	Protein conserved in bacteria
NtRootD5_40100	COG2217	Heavy metal translocating P-type atpase
NtRootD5_40210	COG0534	Mate efflux family protein
NtRootD5_40230	COG2259	Doxx family
NtRootD5_40260	COG0574	Belongs to the PEP-utilizing enzyme family
NtRootD5_40260	COG3848	Pyruvate phosphate dikinase
NtRootD5_40280	COG1607	acyl-coa hydrolase
NtRootD5_40310	COG3958	Transketolase
NtRootD5_40320	COG3959	Transketolase, thiamine diphosphate binding domain
NtRootD5_40350	COG1028	Short-chain dehydrogenase reductase Sdr
NtRootD5_40360	COG2376	Dihydroxyacetone kinase
NtRootD5_40370	COG0698	ribose 5-phosphate isomerase
NtRootD5_40400	COG0305	Participates in initiation and elongation during chromosome replication
NtRootD5_40480	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NtRootD5_40490	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NtRootD5_40560	COG1131	(ABC) transporter
NtRootD5_40580	COG0384	phenazine biosynthesis protein PhzF
NtRootD5_40600	COG2826	transposase and inactivated derivatives, IS30 family
NtRootD5_40610	COG0359	binds to the 23S rRNA
NtRootD5_40620	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NtRootD5_40640	COG0360	Binds together with S18 to 16S ribosomal RNA
NtRootD5_40670	COG1113	amino acid transport
NtRootD5_40680	COG1362	aminopeptidase activity
NtRootD5_40750	COG0833	amino acid
NtRootD5_40760	COG2197	response regulator
NtRootD5_40770	COG4585	Histidine kinase
NtRootD5_40790	COG1131	(ABC) transporter
NtRootD5_40800	COG1597	lipid kinase activity
NtRootD5_40820	COG0738	Major facilitator superfamily
NtRootD5_40860	COG0768	penicillin binding
NtRootD5_40870	COG1501	Belongs to the glycosyl hydrolase 31 family
NtRootD5_40880	COG2197	response regulator
NtRootD5_40890	COG4585	Histidine kinase
NtRootD5_40910	COG1136	(ABC) transporter
NtRootD5_40920	COG1733	regulation of RNA biosynthetic process
NtRootD5_40930	COG2910	NAD(P)H-binding
NtRootD5_40970	COG0406	alpha-ribazole phosphatase activity
NtRootD5_40980	COG0617	tRNA 3'-terminal CCA addition
NtRootD5_41020	COG0492	ferredoxin-NADP+ reductase activity
NtRootD5_41030	COG3118	belongs to the thioredoxin family
NtRootD5_41080	COG1192	Involved in chromosome partitioning
NtRootD5_41090	COG0357	Ribosomal RNA small subunit methyltransferase G
NtRootD5_41110	COG0706	membrane insertase activity
NtRootD5_41120	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NtRootD5_41130	COG0594	ribonuclease P activity
NtRootD5_41140	COG0230	Belongs to the bacterial ribosomal protein bL34 family
NtRootD5_41220	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NtRootD5_41220	COG3608	succinylglutamate desuccinylase aspartoacylase
NtRootD5_41330	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NtRootD5_41360	COG0179	Fumarylacetoacetate (FAA) hydrolase
NtRootD5_41450	COG4974	Belongs to the 'phage' integrase family
NtRootD5_41510	COG1204	response to ionizing radiation
NtRootD5_41530	COG1929	Belongs to the glycerate kinase type-1 family
NtRootD5_41570	COG0673	inositol 2-dehydrogenase activity
NtRootD5_41620	COG2826	transposase and inactivated derivatives, IS30 family
NtRootD5_41650	COG1172	Belongs to the binding-protein-dependent transport system permease family
NtRootD5_41660	COG1129	ABC transporter
NtRootD5_41720	COG4124	Belongs to the glycosyl hydrolase 26 family
NtRootD5_41790	COG2720	vancomycin resistance protein
NtRootD5_41910	COG1475	DNA binding
NtRootD5_41920	COG1609	Transcriptional regulator
NtRootD5_41930	COG2814	Major facilitator Superfamily
NtRootD5_41940	COG0657	acetylesterase activity
NtRootD5_41970	COG2267	carboxylic ester hydrolase activity
NtRootD5_42000	COG1793	dna ligase
NtRootD5_42060	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NtRootD5_42480	COG2211	Major facilitator Superfamily
NtRootD5_42610	COG2801	Transposase and inactivated derivatives
NtRootD5_42610	COG3415	Transposase