locus-tag	class	description
E5206_00010	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
E5206_00015	ENOG4105C6E	dna polymerase iii
E5206_00050	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
E5206_00070	ENOG4108HQS	Glycine betaine
E5206_00075	ENOG4108IJ7	Glycine betaine
E5206_00080	ENOG4105C26	Dehydrogenase
E5206_00105	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
E5206_00110	ENOG4105DVW	rieske (2Fe-2S)
E5206_00115	ENOG4105J4Q	Transcriptional regulator
E5206_00140	ENOG4105CSH	Transporter
E5206_00170	ENOG4105CV8	reductase
E5206_00180	ENOG4108VC7	Protein of unknown function (DUF2587)
E5206_00190	ENOG4105D22	carbon starvation protein
E5206_00200	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
E5206_00230	ENOG41076QQ	Glycosyl transferase, family 2
E5206_00265	ENOG4105C9U	ATP-dependent DNA helicase RecQ
E5206_00270	ENOG4107QKV	phosphomannomutase
E5206_00285	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
E5206_00290	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
E5206_00300	ENOG4105FDP	GntR family transcriptional regulator
E5206_00305	ENOG4107QN2	dihydrolipoyl dehydrogenase
E5206_00315	ENOG4105ECB	domain protein
E5206_00320	ENOG4108IG5	Transcriptional regulator
E5206_00335	ENOG4105M4E	phosphohistidine phosphatase, SixA
E5206_00355	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
E5206_00360	ENOG4105BZU	Histidine kinase
E5206_00375	ENOG4105EDW	glycosyl transferase, family 39
E5206_00375	ENOG4105EDW	glycosyl transferase, family 39
E5206_00380	ENOG4105EDW	glycosyl transferase, family 39
E5206_00395	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
E5206_00400	ENOG410841Q	phosphoesterase PA-phosphatase related protein
E5206_00405	ENOG4108Z6B	deaminase
E5206_00415	ENOG4107STW	synthase
E5206_00450	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
E5206_00455	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
E5206_00470	ENOG4107YVI	ribose 5-phosphate isomerase
E5206_00475	ENOG4105CMT	Dihydroxyacetone kinase
E5206_00515	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
E5206_00520	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
E5206_00545	ENOG4107QRT	dEAD DEAH box helicase
E5206_00550	ENOG4108S0J	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates (By similarity)
E5206_00555	ENOG4108VW9	Membrane
E5206_00575	ENOG4108W1A	pseudouridine synthase
E5206_00580	ENOG4107XFB	conserved TRANSMEMBRANE PROTEIN
E5206_00590	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
E5206_00620	ENOG4105C1G	acyl-Coa dehydrogenase
E5206_00645	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
E5206_00690	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
E5206_00710	ENOG4105C7K	acetolactate synthase
E5206_00720	ENOG4108IMY	Transcriptional regulator
E5206_00730	ENOG4107R9S	Malate synthase
E5206_00775	ENOG4105C39	capsular polysaccharide phosphotransferase
E5206_00780	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
E5206_00785	ENOG4105E2A	Dehydrogenase
E5206_00790	ENOG4108V06	Glutathione peroxidase
E5206_00795	ENOG4105E4C	Lytic transglycosylase catalytic
E5206_00820	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
E5206_00825	ENOG4105CFH	Aspartokinase
E5206_00840	ENOG4105K56	Transcriptional regulator
E5206_00875	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
E5206_00880	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
E5206_00900	ENOG4105PMW	Domain of unknown function (DUF1990)
E5206_00905	ENOG4105MSB	protein, conserved in bacteria
E5206_00915	ENOG4105K4P	CoA-binding domain protein
E5206_00925	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
E5206_00930	ENOG4105FBW	Monooxygenase
E5206_00940	ENOG4105K4P	CoA-binding domain protein
E5206_00960	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
E5206_00965	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
E5206_00980	ENOG4107RCW	fructose-bisphosphate aldolase
E5206_00985	ENOG4108JEZ	rRNA small subunit methyltransferase G
E5206_01010	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
E5206_01045	ENOG4105D17	glycoside hydrolase, family 3 domain protein
E5206_01050	ENOG4105CXK	mandelate racemase muconate lactonizing
E5206_01055	ENOG4105CT4	transporter
E5206_01060	ENOG4105CNT	hydrolase family 2
E5206_01065	ENOG4105DEI	Mannitol dehydrogenase
E5206_01070	ENOG4105D2H	Uronic isomerase
E5206_01075	ENOG4105ETE	Transcriptional regulator (LacI family
E5206_01080	ENOG4105CK5	oxidoreductase
E5206_01095	ENOG4105C3U	ABC transporter
E5206_01110	ENOG4105EPC	oxidoreductase
E5206_01120	ENOG4105ETE	Transcriptional regulator (LacI family
E5206_01150	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
E5206_01165	ENOG4107TYC	hydantoinase B oxoprolinase
E5206_01170	ENOG4107RID	5-oxoprolinase (ATP-hydrolyzing)
E5206_01175	ENOG4105RQI	acetone carboxylase gamma subunit
E5206_01180	ENOG4107SZ9	Hydantoinase oxoprolinase
E5206_01185	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
E5206_01190	ENOG4105CPQ	Dehydrogenase
E5206_01200	ENOG4107R95	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
E5206_01215	ENOG4106WTF	Glycosyl transferase, family 2
E5206_01220	ENOG4105VEQ	Cold shock protein
E5206_01235	ENOG4105C1G	acyl-Coa dehydrogenase
E5206_01240	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
E5206_01255	ENOG4105E39	Enoyl-CoA hydratase
E5206_01270	ENOG4105C26	Dehydrogenase
E5206_01285	ENOG4105ETE	Transcriptional regulator (LacI family
E5206_01305	ENOG4107FKK	extracellular solute-binding protein family 1
E5206_01330	ENOG4105VBF	alkaline shock protein
E5206_01365	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
E5206_01370	ENOG4107Y9U	Membrane
E5206_01405	ENOG4107R95	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
E5206_01425	ENOG4105C7N	Xanthine uracil vitamin C permease
E5206_01430	ENOG41088SP	formiminoglutamate hydrolase
E5206_01440	ENOG4105DAX	Pfam:DUF2983
E5206_01465	ENOG4105CDW	Resistance protein
E5206_01495	ENOG4105C84	Histidine ammonia-lyase
E5206_01500	ENOG4105CGP	Urocanate hydratase
E5206_01515	ENOG4105C85	amino acid
E5206_01530	ENOG4105CR8	Transcriptional regulator
E5206_01555	ENOG4107S2Z	UPF0761 membrane protein
E5206_01630	ENOG4106BRA	Membrane
E5206_01650	ENOG4108IUE	nitrate reductase beta subunit
E5206_01660	ENOG4105E7W	lamb ycsf family protein
E5206_01680	ENOG4108PJD	permease
E5206_01715	ENOG4108638	50S ribosomal protein L36
E5206_01755	ENOG4105X0D	Fimbrial protein
E5206_01765	ENOG4105CZX	twitching motility protein
E5206_01770	ENOG4107QHF	type ii secretion system protein e
E5206_01780	ENOG4107UVD	Beta-phosphoglucomutase family hydrolase
E5206_01785	ENOG4105ETE	Transcriptional regulator (LacI family
E5206_01800	ENOG4105E98	transcriptional regulator DeoR family
E5206_01810	ENOG4105DM4	PTS System
E5206_01820	ENOG4105FDF	Could be involved in DNA repair (By similarity)
E5206_01830	ENOG4108RVA	ribokinase
E5206_01835	ENOG41080V3	Major Facilitator superfamily
E5206_01840	ENOG4105DU0	nucleoside hydrolase
E5206_01860	ENOG4105CSH	Transporter
E5206_01870	ENOG4105EMU	Dehydrogenase
E5206_01885	ENOG4105D2N	Aldolase
E5206_01890	ENOG4105C6Z	Gluconate
E5206_01905	ENOG4105EMF	GntR family transcriptional regulator
E5206_01910	ENOG4105VPX	protein, conserved in bacteria
E5206_01920	ENOG4105WKW	Pfam:DUF1458
E5206_01925	ENOG4105CPC	Aldo Keto reductase
E5206_01930	ENOG4105Y3U	Transglycosylase-associated protein
E5206_01940	ENOG4105BZU	Histidine kinase
E5206_01960	ENOG4105CJ3	phosphate transporter
E5206_01965	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
E5206_02010	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
E5206_02015	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
E5206_02040	ENOG4107HP6	Transcriptional regulator
E5206_02050	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
E5206_02070	ENOG4105VDH	Dihydroxyacetone kinase
E5206_02075	ENOG4108UTZ	Dihydroxyacetone kinase
E5206_02080	ENOG4105CMT	Dihydroxyacetone kinase
E5206_02090	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E5206_02105	ENOG4105CRK	lysyL-tRNA synthetase
E5206_02125	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
E5206_02150	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E5206_02160	ENOG4105EEI	dihydropteroate synthase
E5206_02165	ENOG4105EUJ	GTP cyclohydrolase i
E5206_02170	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
E5206_02180	ENOG4107RD1	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
E5206_02205	ENOG410667J	hydrolase
E5206_02210	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
E5206_02215	ENOG4107TE5	Lipid kinase
E5206_02230	ENOG4105VFE	sira family
E5206_02240	ENOG4105DKK	Benzoate
E5206_02245	ENOG4108QMY	dioxygenase
E5206_02250	ENOG4105FUY	alpha subunit
E5206_02255	ENOG4108UKV	benzoate 1,2-dioxygenase
E5206_02275	ENOG4105NN7	muconolactone delta-isomerase
E5206_02280	ENOG4105DTQ	mandelate racemase muconate lactonizing
E5206_02285	ENOG4107RSM	transcriptional regulator
E5206_02290	ENOG4105D2S	major facilitator superfamily
E5206_02305	ENOG4105DUX	Transporter
E5206_02325	ENOG4105CSV	Glutaminase
E5206_02340	ENOG4105BZU	Histidine kinase
E5206_02350	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
E5206_02355	ENOG4105C2W	permease
E5206_02365	ENOG4105C2C	drug resistance transporter, Bcr CflA
E5206_02375	ENOG4105BZW	Glycerate kinase
E5206_02380	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
E5206_02390	ENOG4108K4B	hydrolase
E5206_02410	ENOG4105D2S	major facilitator superfamily
E5206_02425	ENOG4107TPS	domain protein
E5206_02430	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
E5206_02460	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
E5206_02465	ENOG4108IG5	Transcriptional regulator
E5206_02475	ENOG4105C09	Bile acid
E5206_02480	ENOG4107P2S	Transcriptional regulator
E5206_02495	ENOG4105E5Q	amino acid AbC transporter
E5206_02510	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
E5206_02520	ENOG4105CPU	Monooxygenase
E5206_02535	ENOG4105EAB	amino acid AbC transporter
E5206_02575	ENOG4105CHR	reductase
E5206_02595	ENOG4107HP6	Transcriptional regulator
E5206_02600	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
E5206_02610	ENOG4108JIK	carboxylase
E5206_02620	ENOG4105CSH	Transporter
E5206_02625	ENOG4105E7W	lamb ycsf family protein
E5206_02635	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
E5206_02640	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
E5206_02645	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
E5206_02650	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
E5206_02660	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
E5206_02685	ENOG4108YZ9	Urea amidohydrolase subunit gamma
E5206_02720	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
E5206_02765	ENOG4105TV9	FHA Domain-Containing protein
E5206_02770	ENOG4105HZM	Fha domain containing protein
E5206_02785	ENOG4105CJN	penicillin-binding protein
E5206_02790	ENOG4107TPY	serine threonine protein kinase
E5206_02815	ENOG4105C3U	ABC transporter
E5206_02820	ENOG4108JQ7	(ABC) transporter
E5206_02825	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
E5206_02830	ENOG4105DKQ	ROK family
E5206_02835	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
E5206_02840	ENOG4105CE4	GlcNAc 6-P deacetylase
E5206_02845	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
E5206_02855	ENOG4105I82	acetyl xylan esterase
E5206_02870	ENOG4105EDW	glycosyl transferase, family 39
E5206_02890	ENOG4105E2A	Dehydrogenase
E5206_02935	ENOG4105C3M	thioredoxin reductase
E5206_02955	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
E5206_02995	ENOG4108U4N	(sortase) family
E5206_03000	ENOG4105ZJT	Cell division protein CrgA
E5206_03005	ENOG4108R3E	Dna-3-methyladenine glycosylase i
E5206_03025	ENOG4107R8N	Glycosyl transferase, family 2
E5206_03050	ENOG4108ZED	Transmembrane domain of unknown function (DUF3566)
E5206_03055	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E5206_03060	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E5206_03065	ENOG4105K7N	UPF0232 protein
E5206_03070	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
E5206_03075	ENOG4108J5G	6-phosphogluconate dehydrogenase
E5206_03080	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
E5206_03085	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
E5206_03090	ENOG41084CH	50S ribosomal protein l34
E5206_03100	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
E5206_03105	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
E5206_03115	ENOG4107XUG	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
E5206_03120	ENOG4107QJE	Chromosome Partitioning Protein
E5206_03170	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E5206_03190	ENOG4105K63	Thioredoxin
E5206_03195	ENOG4105C3M	thioredoxin reductase
E5206_03215	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
E5206_03220	ENOG4108ZM9	phosphoglycerate mutase
E5206_03235	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
E5206_03240	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
E5206_03245	ENOG4105BZU	Histidine kinase
E5206_03250	ENOG4105WH1	Two component transcriptional regulator luxr family
E5206_03255	ENOG4105CJN	penicillin-binding protein
E5206_03260	ENOG4105C5H	ABC transporter
E5206_03265	ENOG4106UW1	Major Facilitator superfamily
E5206_03275	ENOG4105CJ1	ABC, transporter
E5206_03285	ENOG4105C85	amino acid
E5206_03295	ENOG4105DFM	M18 family aminopeptidase
E5206_03345	ENOG4105CND	Glycosyl transferase, family 2
E5206_03360	ENOG4107S6X	Glycosyl transferase, family 2
E5206_03370	ENOG4105WH1	Two component transcriptional regulator luxr family
E5206_03380	ENOG410829C	Binds together with S18 to 16S ribosomal RNA (By similarity)
E5206_03390	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
E5206_03395	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
E5206_03400	ENOG4108UZX	fmn reductase
E5206_03415	ENOG4105CDU	Replicative dna helicase
E5206_03420	ENOG4105D5U	fad dependent oxidoreductase
E5206_03430	ENOG4106NZI	LysR family Transcriptional regulator
E5206_03435	ENOG4105CRW	Short chain fatty acid transporter
E5206_03445	ENOG4105NQG	DoxX
E5206_03470	ENOG4108UZ3	Transporter
E5206_03485	ENOG4105VPX	protein, conserved in bacteria
E5206_03520	ENOG4105J4Q	Transcriptional regulator
E5206_03525	ENOG4107S9B	Shikimate dehydrogenase
E5206_03530	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
E5206_03540	ENOG4105RM9	Protocatechuate 3,4-dioxygenase alpha
E5206_03545	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
E5206_03555	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
E5206_03560	ENOG4105CHU	acetyl-coa acetyltransferase
E5206_03570	ENOG4107QNJ	CoA-transferase subunit B
E5206_03575	ENOG4107HP6	Transcriptional regulator
E5206_03585	ENOG4105CBD	Diacylglycerol kinase
E5206_03590	ENOG4105D3Q	Sugar transferase
E5206_03595	ENOG4107TYG	Oxidoreductase domain-containing protein
E5206_03600	ENOG4105CMR	udp-glucose 4-epimerase
E5206_03605	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
E5206_03615	ENOG4105J5G	Transferase hexapeptide repeat containing protein
E5206_03620	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
E5206_03635	ENOG4105D2S	major facilitator superfamily
E5206_03655	ENOG4105NAU	thioesterase Superfamily protein
E5206_03665	ENOG4105C7I	Dehydrogenase
E5206_03675	ENOG4107QTF	adenylosuccinate lyase
E5206_03690	ENOG41082T9	Membrane
E5206_03695	ENOG4105CIH	Imidazole acetol-phosphate transaminase
E5206_03705	ENOG4105CPP	Dehydrogenase, E1 component
E5206_03710	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
E5206_03720	ENOG4108QMY	dioxygenase
E5206_03740	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
E5206_03775	ENOG4105D9R	oxidoreductase
E5206_03780	ENOG4105DCF	alanine dehydrogenase
E5206_03800	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
E5206_03810	ENOG4105CTS	PTS system mannitol-specific
E5206_03815	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
E5206_03825	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
E5206_03835	ENOG4108SGK	Tetr family transcriptional regulator
E5206_03865	ENOG4105F7P	transcriptional regulator AsnC family
E5206_03875	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
E5206_03880	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
E5206_03900	ENOG4108IJ0	Aspartate ammonia-lyase
E5206_03910	ENOG4105JXH	GntR family transcriptional regulator
E5206_03920	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
E5206_03945	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
E5206_03950	ENOG4105VTW	prevent-host-death family
E5206_04025	ENOG4105ECR	NmrA family
E5206_04030	ENOG4105CPC	Aldo Keto reductase
E5206_04040	ENOG4105K5B	UPF0225 protein
E5206_04100	ENOG4105GSW	
E5206_04170	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
E5206_04175	ENOG4105KDC	50s ribosomal protein l28
E5206_04180	ENOG4105W0E	50S ribosomal protein L33
E5206_04185	ENOG41080FR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
E5206_04230	ENOG4108426	dNA-binding protein
E5206_04235	ENOG4105E4J	Cytochrome c oxidase caa3-type, assembly factor ctag-related protein
E5206_04250	ENOG4105D7A	ATP-binding protein
E5206_04260	ENOG4105DEN	Luciferase family
E5206_04265	ENOG4105BZP	glycoside hydrolase 15-related
E5206_04280	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
E5206_04290	ENOG4105CUB	amino acid
E5206_04295	ENOG4105C26	Dehydrogenase
E5206_04320	ENOG4105DHP	deoxycytidine triphosphate deaminase
E5206_04340	ENOG4107RWR	Sodium hydrogen exchanger
E5206_04355	ENOG4105D65	subunit l
E5206_04360	ENOG4105MKQ	Monovalent cation H antiporter subunit C
E5206_04365	ENOG4108JPZ	Monovalent cation H antiporter subunit D
E5206_04375	ENOG41080TA	Multiple resistance and ph regulation protein f
E5206_04380	ENOG4105KJM	monovalent cation h antiporter subunit g
E5206_04390	ENOG4105NSK	ABC superfamily ATP binding cassette transporter membrane protein
E5206_04395	ENOG4108JJB	ABC transporter
E5206_04405	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
E5206_04410	ENOG4106PVI	ATP-dependent carboxylate-amine ligase (By similarity)
E5206_04440	ENOG4105EJQ	L-serine dehydratase
E5206_04465	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
E5206_04500	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
E5206_04510	ENOG4105KJF	protein tyrosine phosphatase
E5206_04515	ENOG4107HP6	Transcriptional regulator
E5206_04535	ENOG4108KC1	acyl-Coa dehydrogenase
E5206_04540	ENOG4108KHK	Glyoxalase Bleomycin resistance protein (Dioxygenase
E5206_04550	ENOG4108KC1	acyl-Coa dehydrogenase
E5206_04565	ENOG4108PGP	mmge prpd family protein
E5206_04570	ENOG4108IV0	ABC, transporter
E5206_04575	ENOG4105C0Z	ABC transporter
E5206_04590	ENOG41067SE	Tetr family transcriptional regulator
E5206_04605	ENOG4107EFR	Flavocytochrome c
E5206_04625	ENOG4107EFR	Flavocytochrome c
E5206_04635	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
E5206_04655	ENOG4105CHU	acetyl-coa acetyltransferase
E5206_04660	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
E5206_04680	ENOG4105CHR	reductase
E5206_04690	ENOG4105C1G	acyl-Coa dehydrogenase
E5206_04700	ENOG4105CSH	Transporter
E5206_04750	ENOG4107KWJ	von Willebrand factor, type A
E5206_04795	ENOG4105CFG	Acts as a chaperone (By similarity)
E5206_04800	ENOG4108093	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
E5206_04805	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
E5206_04810	ENOG4105KNI	merR family transcriptional Regulator
E5206_04820	ENOG4105C0D	helicase
E5206_04850	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
E5206_04860	ENOG4105DJ2	Major Facilitator Superfamily
E5206_04880	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
E5206_04885	ENOG4106F60	Histidine kinase
E5206_04895	ENOG4105CJ2	(LipO)protein
E5206_04905	ENOG4107QIZ	NADH dehydrogenase
E5206_04915	ENOG4105IIV	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity (By similarity)
E5206_04920	ENOG4105C1J	atp-dependent rna helicase
E5206_04935	ENOG41090B9	response to stress
E5206_04940	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
E5206_04945	ENOG4108YYC	ycei family
E5206_04965	ENOG4105X1Q	TOBE domain protein
E5206_04985	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
E5206_04990	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E5206_05010	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
E5206_05035	ENOG4107TFQ	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
E5206_05125	ENOG4105CPQ	Dehydrogenase
E5206_05130	ENOG4105D7K	pfkb domain protein
E5206_05150	ENOG4105CH2	amidohydrolase
E5206_05165	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
E5206_05180	ENOG4105C2C	drug resistance transporter, Bcr CflA
E5206_05195	ENOG4105CEY	Amp-dependent synthetase and ligase
E5206_05205	ENOG41082F9	transcriptional regulator
E5206_05230	ENOG4105CNV	Aldolase
E5206_05245	ENOG4105CSH	Transporter
E5206_05300	ENOG4105D2S	major facilitator superfamily
E5206_05310	ENOG4105FP9	thiamine pyrophosphate
E5206_05320	ENOG4107R7Y	intracellular protease Pfpi family
E5206_05325	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
E5206_05330	ENOG4105CPQ	Dehydrogenase
E5206_05350	ENOG4105CSH	Transporter
E5206_05360	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
E5206_05370	ENOG4105CV8	reductase
E5206_05375	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
E5206_05390	ENOG4108MUZ	hydrolase
E5206_05395	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
E5206_05400	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
E5206_05435	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
E5206_05445	ENOG4105F1N	DNA alkylation repair
E5206_05455	ENOG4107X2D	transcriptional regulator, merr family
E5206_05465	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
E5206_05490	ENOG4105BZP	glycoside hydrolase 15-related
E5206_05525	ENOG4105C12	Phosphoribosylglycinamide synthetase
E5206_05530	ENOG4105C8V	SAICAR synthetase
E5206_05550	ENOG4105BZ1	(ABC) transporter
E5206_05555	ENOG4105BZ1	(ABC) transporter
E5206_05560	ENOG4107RGJ	metallophosphoesterase
E5206_05565	ENOG4105BZ4	penicillin-binding protein
E5206_05595	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
E5206_05605	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
E5206_05620	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
E5206_05630	ENOG4105C2M	dna polymerase I
E5206_05670	ENOG4108I5C	dEAD DEAH box helicase
E5206_05680	ENOG4105C72	UPF0176 protein
E5206_05695	ENOG4108Z6Z	Transcriptional regulator
E5206_05700	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
E5206_05710	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
E5206_05725	ENOG4105GRZ	Ycii-related protein
E5206_05730	ENOG4105II7	pyrroline-5-carboxylate reductase
E5206_05740	ENOG4105CZN	Potassium uptake protein
E5206_05745	ENOG4105DGU	Histone deacetylase
E5206_05750	ENOG41082BM	Transcriptional regulator, arsr family
E5206_05755	ENOG4105D82	Glutamate dehydrogenase
E5206_05765	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
E5206_05780	ENOG4108RXW	HAD-superfamily subfamily IB hydrolase
E5206_05790	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
E5206_05805	ENOG4108YYC	ycei family
E5206_05810	ENOG4108RH7	phosphoglycerate mutase
E5206_05815	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E5206_05820	ENOG4107QIV	Cytochrome c biogenesis protein
E5206_05830	ENOG4105CRE	cytochrome C
E5206_05860	ENOG4107SIQ	Naphthoate synthase
E5206_05875	ENOG4105C85	amino acid
E5206_05885	ENOG41067RQ	csbd family
E5206_05900	ENOG4105CHU	acetyl-coa acetyltransferase
E5206_05905	ENOG4105E39	Enoyl-CoA hydratase
E5206_05910	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
E5206_05945	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
E5206_05950	ENOG4105KA0	thioesterase Superfamily protein
E5206_05955	ENOG4105DXM	phenylacetic acid degradation protein
E5206_05980	ENOG4108ZJI	phenylacetic acid degradation protein
E5206_05985	ENOG4105C6K	Malic enzyme
E5206_05990	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
E5206_05995	ENOG4108YYQ	gCN5-related N-acetyltransferase
E5206_06005	ENOG4107S2E	monooxygenase
E5206_06035	ENOG4108KGH	TRANSCRIPTIONal
E5206_06040	ENOG4106PVI	ATP-dependent carboxylate-amine ligase (By similarity)
E5206_06045	ENOG4107ZF2	Phosphatase
E5206_06050	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
E5206_06055	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
E5206_06060	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
E5206_06065	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
E5206_06070	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
E5206_06075	ENOG4105CGU	Enoyl-CoA hydratase
E5206_06080	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
E5206_06100	ENOG4107QQG	Dehydrogenase
E5206_06105	ENOG4107YJ4	chain length determinant protein
E5206_06140	ENOG4105EW9	transcriptional regulator AsnC family
E5206_06150	ENOG4105CPP	Dehydrogenase, E1 component
E5206_06155	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
E5206_06160	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
E5206_06165	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
E5206_06175	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
E5206_06270	ENOG4105CHM	Aminotransferase
E5206_06285	ENOG4108KXV	response regulator
E5206_06290	ENOG4107TCW	O-succinylbenzoate synthase
E5206_06305	ENOG4105C75	arginyL-tRNA synthetase
E5206_06310	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
E5206_06320	ENOG4105CDA	abc transporter atp-binding protein
E5206_06325	ENOG4105E5Q	amino acid AbC transporter
E5206_06335	ENOG4105E4F	Isochorismate synthase
E5206_06340	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
E5206_06365	ENOG4105EN6	Membrane
E5206_06375	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
E5206_06380	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
E5206_06405	ENOG4108IY8	ABC, transporter
E5206_06420	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
E5206_06440	ENOG4105JXH	GntR family transcriptional regulator
E5206_06455	ENOG4105C26	Dehydrogenase
E5206_06475	ENOG4105BZU	Histidine kinase
E5206_06495	ENOG4107RR1	TRANSCRIPTIONal
E5206_06500	ENOG4105C26	Dehydrogenase
E5206_06515	ENOG4105CUB	amino acid
E5206_06525	ENOG4105CH6	catalase
E5206_06540	ENOG4105D0M	Protease HtpX homolog
E5206_06545	ENOG4108VPT	UPF0234 protein
E5206_06605	ENOG4105CIG	ABC transporter
E5206_06610	ENOG4105DIM	ABC transporter
E5206_06625	ENOG4105D9U	N-acetyltransferase
E5206_06640	ENOG41080RH	Thioredoxin
E5206_06650	ENOG4105CEY	Amp-dependent synthetase and ligase
E5206_06685	ENOG4108U8T	Mannosyltransferase
E5206_06730	ENOG4105C1G	acyl-Coa dehydrogenase
E5206_06780	ENOG4105CG3	alpha amylase, catalytic region
E5206_06785	ENOG4107QM2	Aldo Keto reductase
E5206_06800	ENOG4105CHH	sulfate transporter
E5206_06810	ENOG410900P	UPF0336 protein
E5206_06820	ENOG4106UW1	Major Facilitator superfamily
E5206_06825	ENOG4107R4N	Cell wall formation (By similarity)
E5206_06840	ENOG4107QJH	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
E5206_06850	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
E5206_06855	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
E5206_06865	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
E5206_06870	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
E5206_06875	ENOG4107NHD	transcriptional regulator
E5206_06885	ENOG4108X6U	May play a role in the intracellular transport of hydrophobic ligands
E5206_06945	ENOG4105WH1	Two component transcriptional regulator luxr family
E5206_06960	ENOG410683Z	Preprotein translocase SecE subunit
E5206_06970	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
E5206_06975	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
E5206_06985	ENOG4108VZM	50s ribosomal protein L10
E5206_06990	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
E5206_06995	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
E5206_07000	ENOG4105CHU	acetyl-coa acetyltransferase
E5206_07005	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
E5206_07010	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
E5206_07015	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
E5206_07020	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
E5206_07025	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
E5206_07030	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
E5206_07045	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
E5206_07050	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
E5206_07055	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
E5206_07060	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
E5206_07065	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
E5206_07070	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
E5206_07075	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
E5206_07080	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
E5206_07085	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
E5206_07090	ENOG41082SA	50s ribosomal protein l29
E5206_07095	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
E5206_07100	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
E5206_07105	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
E5206_07110	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
E5206_07115	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
E5206_07120	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
E5206_07125	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
E5206_07130	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
E5206_07135	ENOG410849U	50S ribosomal protein L30
E5206_07150	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
E5206_07170	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
E5206_07175	ENOG4105KXX	peptidase s58 dmpa
E5206_07180	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
E5206_07185	ENOG41067V7	50S ribosomal protein L36
E5206_07190	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
E5206_07195	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
E5206_07200	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
E5206_07205	ENOG4108ZT0	50S ribosomal protein l17
E5206_07210	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
E5206_07240	ENOG4107QMS	site-determining protein
E5206_07275	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
E5206_07280	ENOG4108UJD	30S ribosomal protein S9
E5206_07290	ENOG4105EDW	glycosyl transferase, family 39
E5206_07290	ENOG4105EDW	glycosyl transferase, family 39
E5206_07300	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
E5206_07305	ENOG41080FJ	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
E5206_07310	ENOG4108UZE	carboxy-peptidase
E5206_07315	ENOG4105CS9	pantothenic acid kinase
E5206_07320	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
E5206_07325	ENOG41082KK	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
E5206_07350	ENOG4105CPC	Aldo Keto reductase
E5206_07360	ENOG4105CKU	formyltetrahydrofolate synthetase
E5206_07365	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
E5206_07370	ENOG4105F8D	glycoside hydrolase family 4
E5206_07375	ENOG4105DE4	1-phosphofructokinase
E5206_07380	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
E5206_07385	ENOG4108097	ATP-binding protein
E5206_07400	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
E5206_07405	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
E5206_07410	ENOG4105D17	glycoside hydrolase, family 3 domain protein
E5206_07415	ENOG4105F9E	Shikimate 5-dehydrogenase
E5206_07430	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
E5206_07435	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
E5206_07440	ENOG4105EXC	Acyl-transferase
E5206_07445	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
E5206_07450	ENOG4105BZ1	(ABC) transporter
E5206_07455	ENOG4107QVP	Dehydrogenase
E5206_07460	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
E5206_07480	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
E5206_07500	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
E5206_07505	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
E5206_07575	ENOG41082SX	arsR family transcriptional regulator
E5206_07600	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
E5206_07605	ENOG4105C5H	ABC transporter
E5206_07620	ENOG4105D7N	magnesium and cobalt transport protein CorA
E5206_07645	ENOG4105D94	Major Facilitator Superfamily
E5206_07650	ENOG4107QWG	2-Nitropropane dioxygenase
E5206_07655	ENOG4105RD7	BadF BadG BcrA BcrD
E5206_07670	ENOG4107T5X	Binding-protein-dependent transport systems, inner membrane component
E5206_07675	ENOG4107T5X	Binding-protein-dependent transport systems, inner membrane component
E5206_07690	ENOG4105CSR	polyphosphate kinase 2
E5206_07695	ENOG4105YX8	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
E5206_07700	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
E5206_07710	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
E5206_07720	ENOG4105C3G	gtp-binding protein
E5206_07725	ENOG4108J59	Extracellular solute-binding protein, family 5
E5206_07735	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
E5206_07745	ENOG4108JQ6	ABC transporter
E5206_07750	ENOG4108EVY	peptide transport periplasmic protein
E5206_07755	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
E5206_07760	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
E5206_07775	ENOG4105CI3	gtp-binding protein typa
E5206_07795	ENOG4108Z4U	Ferredoxin
E5206_07810	ENOG4105CMR	udp-glucose 4-epimerase
E5206_07815	ENOG4105W1N	transcriptional regulator
E5206_07830	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
E5206_07835	ENOG4107R4C	succinyl-diaminopimelate desuccinylase
E5206_07840	ENOG4105DRP	amino acid AbC transporter
E5206_07845	ENOG4108Q1T	ABC transporter
E5206_07855	ENOG4105CDA	abc transporter atp-binding protein
E5206_07860	ENOG4108URH	decarboxylase
E5206_07885	ENOG4105DU6	RNA polymerase
E5206_07895	ENOG4105UTW	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
E5206_07900	ENOG4105D1F	ATP-binding protein
E5206_07910	ENOG4105CJW	magnesium transporter
E5206_07940	ENOG4107T6F	Xaa-Pro aminopeptidase
E5206_07945	ENOG4105DB7	PHP domain protein
E5206_07950	ENOG4105CEC	DNA methylase N-4 N-6
E5206_07955	ENOG4105C1J	atp-dependent rna helicase
E5206_07970	ENOG4107Y5I	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
E5206_07975	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
E5206_07985	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
E5206_08025	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
E5206_08045	ENOG4107QME	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
E5206_08050	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
E5206_08060	ENOG4105D52	delta-aminolevulinic acid dehydratase
E5206_08070	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
E5206_08080	ENOG4105E5Q	amino acid AbC transporter
E5206_08085	ENOG4105EAB	amino acid AbC transporter
E5206_08115	ENOG4105E09	nadh pyrophosphatase
E5206_08135	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
E5206_08140	ENOG4105DJZ	UPF0182 protein
E5206_08155	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
E5206_08160	ENOG41087YS	Phage shock protein A
E5206_08170	ENOG4105C0H	protease
E5206_08175	ENOG4105BZJ	Electron transfer flavoprotein
E5206_08180	ENOG4105C10	Electron transfer flavoprotein
E5206_08185	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
E5206_08190	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
E5206_08195	ENOG4105C6Z	Gluconate
E5206_08210	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
E5206_08240	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
E5206_08290	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
E5206_08295	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
E5206_08300	ENOG4108JQ6	ABC transporter
E5206_08330	ENOG4108T3R	lipoprotein lpqB
E5206_08335	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
E5206_08340	ENOG4108S7Q	sigma 54 modulation protein ribosomal protein S30ea
E5206_08345	ENOG4105T0Z	Conserved Protein
E5206_08350	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
E5206_08385	ENOG4105C7I	Dehydrogenase
E5206_08415	ENOG410602S	Transferase
E5206_08425	ENOG4105EY8	ABC transporter
E5206_08435	ENOG4107QPT	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
E5206_08455	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
E5206_08465	ENOG4105BZU	Histidine kinase
E5206_08470	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
E5206_08475	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
E5206_08550	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
E5206_08555	ENOG4105CAK	Cell division ATP-binding protein ftsE
E5206_08560	ENOG4107RYD	Part of the ABC transporter FtsEX involved in cellular division (By similarity)
E5206_08565	ENOG41061JJ	Peptidase family M23
E5206_08570	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
E5206_08605	ENOG4105C9B	Cysteine desulfurase
E5206_08610	ENOG4107TK4	histidinol-phosphate phosphatase
E5206_08615	ENOG4105CH2	amidohydrolase
E5206_08630	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
E5206_08640	ENOG4105EMN	RNA polymerase sigma factor
E5206_08665	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
E5206_08690	ENOG4105DIK	(ABC) transporter
E5206_08695	ENOG4105CC5	ABC transporter
E5206_08705	ENOG4105E8R	UPF0173 metal-dependent hydrolase
E5206_08730	ENOG4105DQ4	alcohol dehydrogenase
E5206_08735	ENOG4107ZUX	Histidine triad (HIT) protein
E5206_08740	ENOG4105CQ7	ATP-dependent helicase
E5206_08775	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
E5206_08790	ENOG4105C75	arginyL-tRNA synthetase
E5206_08795	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
E5206_08800	ENOG4105D6E	homoserine dehydrogenase
E5206_08805	ENOG4107R5I	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
E5206_08810	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
E5206_08820	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
E5206_08825	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
E5206_08830	ENOG4107UIY	sua5 ycio yrdc ywlc family protein
E5206_08845	ENOG4105ESV	Glycosyl transferase, family 4
E5206_08860	ENOG4107UH5	it plays a direct role in the translocation of protons across the membrane (By similarity)
E5206_08865	ENOG4106DE0	ATP synthase
E5206_08870	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
E5206_08875	ENOG4108T62	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
E5206_08880	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
E5206_08885	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
E5206_08890	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
E5206_08895	ENOG410825K	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
E5206_08905	ENOG4108SEA	Esterase
E5206_08910	ENOG4105FF5	Membrane
E5206_08920	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
E5206_08965	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
E5206_08985	ENOG4108RWI	nicotinamidase
E5206_08995	ENOG4105KEN	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
E5206_09005	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
E5206_09010	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
E5206_09015	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
E5206_09020	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
E5206_09025	ENOG4107XFB	conserved TRANSMEMBRANE PROTEIN
E5206_09045	ENOG4105VG5	Membrane
E5206_09050	ENOG4105JP4	Inner membrane protein yidG
E5206_09065	ENOG4105EYH	Exonuclease
E5206_09070	ENOG41069M3	Transcriptional regulator
E5206_09085	ENOG4105CSH	Transporter
E5206_09090	ENOG4108EMS	branched-chain alpha-keto acid dehydrogenase subunit E2
E5206_09095	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
E5206_09100	ENOG4105CPP	Dehydrogenase, E1 component
E5206_09110	ENOG4105C85	amino acid
E5206_09130	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
E5206_09135	ENOG4108IYU	L-aspartate oxidase
E5206_09140	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
E5206_09145	ENOG4107QI6	Cysteine desulfurase
E5206_09170	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
E5206_09175	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
E5206_09190	ENOG4105DWT	malate dehydrogenase (quinone)
E5206_09195	ENOG4105DEF	Extracellular solute-binding protein, family 5
E5206_09360	ENOG4105DR5	peptidase
E5206_09385	ENOG4105DR5	peptidase
E5206_09615	ENOG4105D8V	Glucose sorbosone dehydrogenase
E5206_09620	ENOG4105K5M	30s ribosomal protein S16
E5206_09625	ENOG4105C01	Dihydroxy-acid dehydratase
E5206_09635	ENOG4108ZP8	Acetolactate synthase small subunit
E5206_09640	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
E5206_09645	ENOG4108JQ1	Dehydrogenase
E5206_09655	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
E5206_09675	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
E5206_09680	ENOG4105CM2	brancheD-chain amino acid aminotransferase
E5206_09690	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
E5206_09695	ENOG4105NTW	Transcriptional regulator
E5206_09700	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
E5206_09775	ENOG4108C33	Resolvase
E5206_09830	ENOG4108YYH	Nadph-dependent fmn reductase
E5206_09865	ENOG4105CSH	Transporter
E5206_09870	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
E5206_09895	ENOG4105EJQ	L-serine dehydratase
E5206_09900	ENOG4108V06	Glutathione peroxidase
E5206_09915	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
E5206_09930	ENOG4108C33	Resolvase
E5206_09955	ENOG41069M3	Transcriptional regulator
E5206_09960	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
E5206_09965	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
E5206_09970	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
E5206_09980	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
E5206_09985	ENOG4105CPF	Cell wall formation (By similarity)
E5206_10000	ENOG4105DP4	dak2 domain fusion protein ylov
E5206_10010	ENOG4106H78	methyltransferase
E5206_10030	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
E5206_10040	ENOG41062IY	50S ribosomal protein L32
E5206_10045	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
E5206_10050	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
E5206_10065	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
E5206_10070	ENOG410680H	amp-dependent synthetase and ligase
E5206_10075	ENOG4105E2T	synthase III
E5206_10085	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
E5206_10105	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
E5206_10120	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
E5206_10130	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
E5206_10140	ENOG4105K5M	30s ribosomal protein S16
E5206_10145	ENOG41082KU	UPF0109 protein
E5206_10150	ENOG4107XUM	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
E5206_10155	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
E5206_10160	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
E5206_10165	ENOG4107QYR	Signal peptidase i
E5206_10175	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
E5206_10185	ENOG41080R2	UPF0102 protein
E5206_10190	ENOG4105C0P	Mg chelatase subunit ChlI
E5206_10200	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E5206_10220	ENOG41082KT	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
E5206_10225	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
E5206_10240	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
E5206_10285	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
E5206_10295	ENOG4105CHR	reductase
E5206_10300	ENOG4105CPQ	Dehydrogenase
E5206_10310	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
E5206_10315	ENOG4105E1F	short-chain dehydrogenase reductase
E5206_10320	ENOG4105D7W	serine acetyltransferase
E5206_10330	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
E5206_10335	ENOG4105EGD	dinuclear metal center protein, YbgI family
E5206_10345	ENOG4107XFJ	UPF0246 protein
E5206_10385	ENOG4105CSR	polyphosphate kinase 2
E5206_10390	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
E5206_10405	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
E5206_10410	ENOG4107JC6	Membrane
E5206_10425	ENOG41060H3	Protein of unknown function (DUF1049)
E5206_10435	ENOG4105D7N	magnesium and cobalt transport protein CorA
E5206_10460	ENOG4105C29	acyl-CoA thioesterase
E5206_10475	ENOG4105D8X	mechanosensitive ion channel
E5206_10495	ENOG4108YZG	isomerase
E5206_10515	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
E5206_10520	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
E5206_10525	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
E5206_10530	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
E5206_10535	ENOG4105MC2	DSBA oxidoreductase
E5206_10540	ENOG4105BZP	glycoside hydrolase 15-related
E5206_10545	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
E5206_10550	ENOG4105K78	MarR family Transcriptional regulator
E5206_10565	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
E5206_10570	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
E5206_10580	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
E5206_10590	ENOG4105C03	ribonuclease
E5206_10595	ENOG4105DWF	phosphomethylpyrimidine kinase
E5206_10600	ENOG410826X	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
E5206_10605	ENOG4105K46	50S ribosomal protein l27
E5206_10610	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
E5206_10615	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
E5206_10620	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
E5206_10630	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
E5206_10655	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
E5206_10660	ENOG4105CAY	ferredoxin--nadp reductase
E5206_10665	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
E5206_10670	ENOG4105E2R	ROK family
E5206_10685	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
E5206_10720	ENOG4105C26	Dehydrogenase
E5206_10740	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
E5206_10750	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
E5206_10755	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
E5206_10760	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
E5206_10765	ENOG4105CB5	ATP-dependent DNA helicase recG
E5206_10775	ENOG4105DZR	Type I site-specific deoxyribonuclease
E5206_10780	ENOG4105DFS	Conserved Protein
E5206_10805	ENOG4107XFB	conserved TRANSMEMBRANE PROTEIN
E5206_10845	ENOG410836F	Transposase
E5206_10850	ENOG410836F	Transposase
E5206_10855	ENOG4105D8X	mechanosensitive ion channel
E5206_10880	ENOG41082SX	arsR family transcriptional regulator
E5206_10890	ENOG4105CJW	magnesium transporter
E5206_10910	ENOG4108KGH	TRANSCRIPTIONal
E5206_10925	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
E5206_10995	ENOG4105C10	Electron transfer flavoprotein
E5206_11035	ENOG4105D7N	magnesium and cobalt transport protein CorA
E5206_11060	ENOG41088T4	Helicase IV
E5206_11065	ENOG41088T4	Helicase IV
E5206_11080	ENOG4105CJ1	ABC, transporter
E5206_11140	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
E5206_11155	ENOG4105C6Z	Gluconate
E5206_11160	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
E5206_11200	ENOG4105BZ1	(ABC) transporter
E5206_11220	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
E5206_11225	ENOG4108MRH	transcriptional regulatory protein
E5206_11235	ENOG4105EXC	Acyl-transferase
E5206_11250	ENOG4105DRP	amino acid AbC transporter
E5206_11255	ENOG4105CDA	abc transporter atp-binding protein
E5206_11325	ENOG4105DU6	RNA polymerase
E5206_11360	ENOG4105GR3	Histidine kinase
E5206_11365	ENOG4105ETX	regulatoR
E5206_11375	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
E5206_11380	ENOG4105NAE	bifunctional deaminase-reductase domain protein
E5206_11450	ENOG4105C5X	domain protein
E5206_11465	ENOG4108RAV	Conserved protein
E5206_11500	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
E5206_11510	ENOG4105BZ4	penicillin-binding protein
E5206_11525	ENOG4108HH4	Major Facilitator Superfamily
E5206_11535	ENOG41080RH	Thioredoxin
E5206_11555	ENOG4108VCT	Sulfite exporter TauE/SafE
E5206_11580	ENOG4105DXI	Major Facilitator superfamily
E5206_11590	ENOG4105XTG	Pfam:DUF156
E5206_11610	ENOG4107JBM	CrcB-like protein
E5206_11615	ENOG41083TI	Protein CrcB homolog
E5206_11645	ENOG4105C0B	DNA polymerase III (alpha subunit)
E5206_11650	ENOG4105C22	threonyL-tRNA synthetase
E5206_11665	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
E5206_11670	ENOG4105DGW	oligopeptidase A
E5206_11685	ENOG4105DMS	mur ligase
E5206_11690	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
E5206_11695	ENOG4105CDY	transcriptional regulatory protein
E5206_11700	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
E5206_11705	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
E5206_11710	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
E5206_11720	ENOG4107RSV	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
E5206_11725	ENOG4107RTU	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
E5206_11730	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
E5206_11740	ENOG4105C99	atpase involved in dna repair
E5206_11750	ENOG4105CUT	histidyl-tRNA synthetase
E5206_11755	ENOG4105KHC	sulfurtransferase
E5206_11760	ENOG4105C9M	aspartyl-trna synthetase
E5206_11765	ENOG4105CSH	Transporter
E5206_11770	ENOG4107HP6	Transcriptional regulator
E5206_11775	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
E5206_11800	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
E5206_11815	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
E5206_11820	ENOG41080G3	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
E5206_11830	ENOG4105E2X	shikimate dehydrogenase
E5206_11835	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
E5206_11840	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
E5206_11845	ENOG4105D49	3-dehydroquinate synthase
E5206_11855	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
E5206_11860	ENOG410803B	Involved in the transcription termination process (By similarity)
E5206_11865	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
E5206_11870	ENOG4105CXT	aspartate transcarbamylase
E5206_11875	ENOG4105CD3	dihydroorotase
E5206_11885	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
E5206_11890	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
E5206_11895	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
E5206_11900	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
E5206_11905	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
E5206_11910	ENOG4105MTQ	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
E5206_11920	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
E5206_11940	ENOG4105CV8	reductase
E5206_11955	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
E5206_11960	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
E5206_11965	ENOG4105C8T	Leucyl-tRNA synthetase
E5206_11970	ENOG4105EPR	degv family
E5206_11985	ENOG4105BZM	domain protein
E5206_12000	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
E5206_12010	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
E5206_12030	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
E5206_12035	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
E5206_12040	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
E5206_12050	ENOG4105MXW	flavin reductase domain protein, FMN-binding
E5206_12060	ENOG4107VNR	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
E5206_12070	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
E5206_12075	ENOG4107TB5	TRANSCRIPTIONal
E5206_12080	ENOG4105C9K	Endothelin-converting enzyme 1
E5206_12085	ENOG4107QXN	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
E5206_12090	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
E5206_12095	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
E5206_12100	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
E5206_12105	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
E5206_12125	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
E5206_12130	ENOG4105BZ9	Cytochrome C oxidase, subunit I
E5206_12135	ENOG4105MCD	Part of cytochrome c oxidase, its function is
E5206_12140	ENOG410849S	phosphocarrier protein (HPr)
E5206_12150	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
E5206_12155	ENOG4107EUI	c reductase, iron-sulfur
E5206_12160	ENOG4107UDY	cytochrome C
E5206_12165	ENOG4105CCU	oxidase (Subunit III)
E5206_12170	ENOG4108I0Q	anthranilate phosphoribosyltransferase
E5206_12200	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
E5206_12215	ENOG4107QSA	Oxaloacetate decarboxylase
E5206_12220	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
E5206_12225	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
E5206_12230	ENOG4108K8U	Glycerol operon regulatory protein
E5206_12240	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
E5206_12255	ENOG4108KEZ	Dehydrogenase
E5206_12270	ENOG4105BZU	Histidine kinase
E5206_12310	ENOG4105CPQ	Dehydrogenase
E5206_12330	ENOG4105CIB	oxidoreductase Domain protein
E5206_12355	ENOG4105C1G	acyl-Coa dehydrogenase
E5206_12365	ENOG4105CI0	Citrate lyase
E5206_12395	ENOG4105EKQ	RNA-directed DNA polymerase
E5206_12405	ENOG4105C26	Dehydrogenase
E5206_12420	ENOG4105C26	Dehydrogenase
E5206_12430	ENOG4108Z86	Glutamine amidotransferase
E5206_12435	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
E5206_12440	ENOG4105C5F	glutamine synthetase
E5206_12455	ENOG4107EJG	GntR family transcriptional regulator
E5206_12490	ENOG41065KQ	synthase
E5206_12510	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
E5206_12535	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
E5206_12540	ENOG4105EFZ	amidohydrolase
E5206_12545	ENOG4105CQR	helicase
E5206_12550	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
E5206_12580	ENOG4105DVV	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine (By similarity)
E5206_12585	ENOG4105F7N	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
E5206_12590	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
E5206_12595	ENOG4105WFD	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation (By similarity)
E5206_12600	ENOG4105E5F	proteasome
E5206_12605	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
E5206_12620	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
E5206_12630	ENOG4105C8N	cysteinyl-tRNA synthetase
E5206_12635	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
E5206_12640	ENOG4105CV8	reductase
E5206_12660	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
E5206_12755	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
E5206_12790	ENOG4105CHF	Glutathione S-transferase
E5206_12805	ENOG4105CHR	reductase
E5206_12810	ENOG4105CHU	acetyl-coa acetyltransferase
E5206_12825	ENOG4107QPH	glycogen) synthase
E5206_12830	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
E5206_12880	ENOG4107ZR7	Membrane
E5206_12895	ENOG4107QN2	dihydrolipoyl dehydrogenase
E5206_12910	ENOG4105NRA	50s ribosomal protein l31 type b
E5206_12925	ENOG4105DKW	ABC transporter
E5206_12930	ENOG4105EAC	phosphoserine phosphatase
E5206_12935	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
E5206_12945	ENOG4105CHR	reductase
E5206_12965	ENOG4105C5H	ABC transporter
E5206_12970	ENOG4107ZYJ	bioY protein
E5206_12975	ENOG4108JJB	ABC transporter
E5206_12990	ENOG4107F3J	Amp-dependent synthetase and ligase
E5206_13000	ENOG4105VG1	fes assembly suf system protein
E5206_13005	ENOG4105C3K	feS assembly ATPase SufC
E5206_13030	ENOG4105CJ1	ABC, transporter
E5206_13040	ENOG4107SGF	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
E5206_13045	ENOG4107XFB	conserved TRANSMEMBRANE PROTEIN
E5206_13050	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
E5206_13060	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
E5206_13080	ENOG4107XU2	6-phosphogluconolactonase (EC 3.1.1.31)
E5206_13095	ENOG4105CP7	Triose-phosphate isomerase
E5206_13100	ENOG4105BZA	Phosphoglycerate kinase
E5206_13105	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
E5206_13110	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
E5206_13115	ENOG4105CIE	May be required for sporulation (By similarity)
E5206_13120	ENOG4105CHW	UPF0052 protein
E5206_13125	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
E5206_13130	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
E5206_13135	ENOG4105CEY	Amp-dependent synthetase and ligase
E5206_13145	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
E5206_13160	ENOG4105BZ1	(ABC) transporter
E5206_13165	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
E5206_13205	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
E5206_13245	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
E5206_13250	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
E5206_13255	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
E5206_13265	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
E5206_13270	ENOG4105HHS	UPF0256 protein
E5206_13280	ENOG4105KA0	thioesterase Superfamily protein
E5206_13285	ENOG4105NAE	bifunctional deaminase-reductase domain protein
E5206_13305	ENOG4105D2S	major facilitator superfamily
E5206_13320	ENOG4105ERH	Fumarylacetoacetate hydrolase
E5206_13335	ENOG4108YV4	Universal stress protein
E5206_13345	ENOG4105CY0	Metallo-Beta-Lactamase
E5206_13350	ENOG4105CEY	Amp-dependent synthetase and ligase
E5206_13390	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
E5206_13415	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
E5206_13435	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
E5206_13460	ENOG4105C4B	ABC transporter, permease
E5206_13475	ENOG4105BZU	Histidine kinase
E5206_13510	ENOG4105EUB	pirin domain protein
E5206_13530	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
E5206_13550	ENOG41087PP	glycosyltransferase MGT family
E5206_13560	ENOG4105CVK	Glutamate decarboxylase
E5206_13570	ENOG4107QZF	nitrite reductase NADPH large subunit
E5206_13585	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
E5206_13590	ENOG4105CK5	oxidoreductase
E5206_13595	ENOG4105ETE	Transcriptional regulator (LacI family
E5206_13600	ENOG4106A3M	Cytochrome p-450
E5206_13605	ENOG4105CQ7	ATP-dependent helicase
E5206_13615	ENOG4105ECR	NmrA family
E5206_13640	ENOG4105W1N	transcriptional regulator
E5206_13645	ENOG41063TF	transcriptional regulator (AraC
E5206_13655	ENOG4105C26	Dehydrogenase
E5206_13660	ENOG4105CSH	Transporter
E5206_13665	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
E5206_13670	ENOG4105GVJ	transcriptional regulator
E5206_13705	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
E5206_13710	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
E5206_13715	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
E5206_13755	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
E5206_13780	ENOG4108IG5	Transcriptional regulator
E5206_13785	ENOG4105C1G	acyl-Coa dehydrogenase
E5206_13790	ENOG4105CEY	Amp-dependent synthetase and ligase
E5206_13795	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
E5206_13800	ENOG4108IAJ	Nad-dependent epimerase dehydratase
E5206_13805	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
E5206_13810	ENOG4105CMR	udp-glucose 4-epimerase
E5206_13835	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
E5206_13845	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
E5206_13875	ENOG4105CN8	Transcriptional regulator
E5206_13900	ENOG4105SUT	Transcriptional Regulator AraC Family
E5206_13905	ENOG4108KC1	acyl-Coa dehydrogenase
E5206_13925	ENOG4107RQ0	Maleylacetate reductase
E5206_13955	ENOG4105CPC	Aldo Keto reductase
E5206_13980	ENOG410836F	Transposase
E5206_13995	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
E5206_14000	ENOG4105ETX	regulatoR
E5206_14005	ENOG4105GR3	Histidine kinase
E5206_14015	ENOG4107T8Q	Glycosyl transferase (Group 1
E5206_14025	ENOG4105BZ1	(ABC) transporter
E5206_14045	ENOG4105FBN	Acid phosphatase
E5206_14065	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
E5206_14085	ENOG4105CHR	reductase
E5206_14090	ENOG4107S9B	Shikimate dehydrogenase
E5206_14100	ENOG4107RSM	transcriptional regulator
E5206_14105	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
E5206_14120	ENOG4105KHM	amidohydrolase 2
E5206_14130	ENOG4105GAK	amidohydrolase 2
E5206_14145	ENOG4105CPC	Aldo Keto reductase
E5206_14175	ENOG41085W3	Transposase
E5206_14200	ENOG410836F	Transposase
E5206_14235	ENOG41090KN	UPF0303 protein
E5206_14300	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
E5206_14320	ENOG4107QM5	aconitate hydratase
E5206_14325	ENOG4105E33	succinate dehydrogenase
E5206_14335	ENOG4105EQW	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
E5206_14340	ENOG4105K78	MarR family Transcriptional regulator
E5206_14345	ENOG4108VX5	3-methyladenine DNA glycosylase
E5206_14355	ENOG4105JP4	Inner membrane protein yidG
E5206_14360	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
E5206_14365	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
E5206_14375	ENOG4105CHU	acetyl-coa acetyltransferase
E5206_14385	ENOG4105C10	Electron transfer flavoprotein
E5206_14395	ENOG4105CEY	Amp-dependent synthetase and ligase
E5206_14410	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
E5206_14415	ENOG4105D2B	acyl-CoA dehydrogenase
E5206_14420	ENOG4105CHU	acetyl-coa acetyltransferase
E5206_14430	ENOG4105CHU	acetyl-coa acetyltransferase
E5206_14445	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
E5206_14460	ENOG4105D2B	acyl-CoA dehydrogenase
E5206_14500	ENOG4106P55	Transcriptional regulator
E5206_14510	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
E5206_14515	ENOG4105CEY	Amp-dependent synthetase and ligase
E5206_14535	ENOG4105CSH	Transporter
E5206_14540	ENOG4105CEY	Amp-dependent synthetase and ligase
E5206_14550	ENOG4105C32	Amino acid ABC transporter (Permease)
E5206_14555	ENOG4105C2J	ABC transporter
E5206_14560	ENOG4108IV0	ABC, transporter
E5206_14570	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
E5206_14590	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
E5206_14595	ENOG4105J7D	transcriptional regulator
E5206_14630	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
E5206_14635	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
E5206_14640	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
E5206_14650	ENOG4105ETE	Transcriptional regulator (LacI family
E5206_14660	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
E5206_14665	ENOG4105CHU	acetyl-coa acetyltransferase
E5206_14670	ENOG4105C26	Dehydrogenase
E5206_14675	ENOG4105E39	Enoyl-CoA hydratase
E5206_14680	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
E5206_14685	ENOG4105F95	Monooxygenase
E5206_14710	ENOG4106NZI	LysR family Transcriptional regulator
E5206_14720	ENOG4105C1G	acyl-Coa dehydrogenase
E5206_14740	ENOG4105CNN	ABC, transporter
E5206_14745	ENOG4105CNN	ABC, transporter
E5206_14755	ENOG4105CHR	reductase
E5206_14760	ENOG4106NZI	LysR family Transcriptional regulator
E5206_14765	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
E5206_14770	ENOG4105F95	Monooxygenase
E5206_14825	ENOG4108IG5	Transcriptional regulator
E5206_14845	ENOG4105D2S	major facilitator superfamily
E5206_14875	ENOG4105ERH	Fumarylacetoacetate hydrolase
E5206_14885	ENOG4105JP4	Inner membrane protein yidG
E5206_14900	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
E5206_14915	ENOG4105CHR	reductase
E5206_14930	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
E5206_14945	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
E5206_14975	ENOG4105CA9	Pyruvate kinase
E5206_14985	ENOG4105CBC	glutamate synthase
E5206_14990	ENOG4107TBN	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
E5206_14995	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
E5206_15000	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
E5206_15005	ENOG4105DK0	Indole-3-glycerol phosphate synthase
E5206_15025	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
E5206_15035	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
E5206_15040	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
E5206_15045	ENOG4105M0N	phosphoribosyl-ATP pyrophosphatase
E5206_15050	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
E5206_15055	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
E5206_15060	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
E5206_15075	ENOG4105DJV	ribulose-phosphate 3-epimerase
E5206_15085	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
E5206_15090	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
E5206_15100	ENOG4107RNG	ABC transporter
E5206_15155	ENOG4108Z66	YbaK ebsC protein
E5206_15160	ENOG4108YYC	ycei family
E5206_15175	ENOG4105E0X	reductase
E5206_15200	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
E5206_15205	ENOG4105CHU	acetyl-coa acetyltransferase
E5206_15210	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
E5206_15215	ENOG4105DU0	nucleoside hydrolase
E5206_15220	ENOG4107SET	aldo keto reductase
E5206_15235	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
E5206_15240	ENOG4107QM5	aconitate hydratase
E5206_15245	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
E5206_15250	ENOG4105C0X	amino acid
E5206_15255	ENOG4107VEG	TrkA-N domain protein
E5206_15280	ENOG4107ZFB	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
E5206_15300	ENOG4107W53	thymidine kinase
E5206_15315	ENOG410870F	Cyclic nucleotide-binding protein
E5206_15320	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E5206_15330	ENOG4108JJ9	ABC, transporter
E5206_15335	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
E5206_15340	ENOG4105C4M	(Ubiquinol oxidase) subunit I
E5206_15355	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E5206_15365	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E5206_15385	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
E5206_15405	ENOG4108Z9K	Osmotically inducible protein
E5206_15410	ENOG4107RE3	peptidase, S41
E5206_15415	ENOG4105ECP	epimerase
E5206_15425	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
E5206_15430	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
E5206_15465	ENOG4105CDA	abc transporter atp-binding protein
E5206_15470	ENOG4105E5Q	amino acid AbC transporter
E5206_15475	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
E5206_15480	ENOG4105C5F	glutamine synthetase
E5206_15485	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
E5206_15505	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
E5206_15510	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
E5206_15525	ENOG4105C0B	DNA polymerase III (alpha subunit)
E5206_15535	ENOG4107ZIW	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
E5206_15540	ENOG4107VQS	DivIVA family
E5206_15550	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
E5206_15555	ENOG4105DFA	alanine racemase domain protein
E5206_15560	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
E5206_15565	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
E5206_15570	ENOG4105ME9	cell division protein FtsQ
E5206_15575	ENOG4105DFU	Cell wall formation (By similarity)
E5206_15580	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
E5206_15585	ENOG4105CNI	cell division protein FtsW
E5206_15590	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
E5206_15595	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
E5206_15600	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
E5206_15605	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
E5206_15610	ENOG4105CJN	penicillin-binding protein
E5206_15620	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
E5206_15625	ENOG4108V6E	Cell division protein mraZ
E5206_15635	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
E5206_15645	ENOG4105EAH	synthase
E5206_15655	ENOG41068JE	domain protein
E5206_15665	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
E5206_15685	ENOG4105DKQ	ROK family
E5206_15695	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
E5206_15700	ENOG4107QJE	Chromosome Partitioning Protein
E5206_15720	ENOG4108UW8	fha domain-containing protein
E5206_15735	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
E5206_15745	ENOG4105CAT	Cytidine monophosphate kinase
E5206_15760	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
E5206_15765	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
E5206_15775	ENOG4105CK2	sodium dicarboxylate symporter
E5206_15780	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
E5206_15785	ENOG4108MRH	transcriptional regulatory protein
E5206_15790	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
E5206_15840	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
E5206_15845	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
E5206_15850	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
E5206_15865	ENOG4105DSU	hydrolase
E5206_15890	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
E5206_15900	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
E5206_15915	ENOG4108VX5	3-methyladenine DNA glycosylase
E5206_15925	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
E5206_15930	ENOG4105CH7	arginosuccinase
E5206_15935	ENOG4105CDH	Citrulline--aspartate ligase
E5206_15940	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
E5206_15945	ENOG4105DBV	ornithine carbamoyltransferase
E5206_15950	ENOG4105C8Y	Acetylornithine aminotransferase
E5206_15955	ENOG4105CAS	nag kinase
E5206_15960	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
E5206_15965	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
E5206_15975	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
E5206_15995	ENOG4105D7K	pfkb domain protein
E5206_16000	ENOG4108HKT	sucrose-6-phosphate hydrolase
E5206_16005	ENOG4105DRS	transport system, permease
E5206_16020	ENOG4105ETE	Transcriptional regulator (LacI family
E5206_16030	ENOG4105QPS	Monooxygenase
E5206_16045	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
E5206_16050	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
E5206_16075	ENOG4105W8H	transhydrogenase (subunit alpha
E5206_16080	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
E5206_16090	ENOG4105F27	Major Facilitator
E5206_16100	ENOG4105Y3U	Transglycosylase-associated protein
E5206_16105	ENOG4108RWN	rrna methyltransferase
E5206_16110	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
E5206_16115	ENOG41084BS	50S ribosomal protein L35
E5206_16120	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
E5206_16130	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
E5206_16135	ENOG4108UMI	ABC transporter, permease
E5206_16140	ENOG4105D01	(LipO)protein
E5206_16160	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
E5206_16165	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
E5206_16170	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
E5206_16175	ENOG4105CIH	Imidazole acetol-phosphate transaminase
E5206_16185	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
E5206_16195	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
E5206_16200	ENOG4107Y49	methyltransferase
E5206_16205	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
E5206_16210	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
E5206_16215	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
E5206_16220	ENOG4105KC9	Modulates RecA activity (By similarity)
E5206_16225	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
E5206_16240	ENOG4105WBV	Transcriptional regulator
E5206_16245	ENOG4105CEV	competence damage-inducible protein
E5206_16255	ENOG4107QZI	cell division protein FtsK
E5206_16260	ENOG4105CN5	Metallo-Beta-Lactamase
E5206_16265	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
E5206_16290	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
E5206_16300	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
E5206_16335	ENOG4105C1V	Peptidase, M16
E5206_16340	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
E5206_16345	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
E5206_16355	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
E5206_16385	ENOG4108JW7	Maf-like protein
E5206_16405	ENOG4105CHM	Aminotransferase
E5206_16420	ENOG4105K63	Thioredoxin
E5206_16425	ENOG4107Y2X	deaminase
E5206_16430	ENOG4107ZPY	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
E5206_16435	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
E5206_16450	ENOG4107Z1I	Required for maturation of 30S ribosomal subunits (By similarity)
E5206_16475	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
E5206_16490	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
E5206_16500	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
E5206_16520	ENOG4105DZP	Membrane-associated zinc metalloprotease
E5206_16525	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
E5206_16555	ENOG4105C1G	acyl-Coa dehydrogenase
E5206_16565	ENOG4107QX3	carboxylase
E5206_16575	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
E5206_16580	ENOG4105CPP	Dehydrogenase, E1 component
E5206_16595	ENOG4107QN1	sodium solute
E5206_16605	ENOG4108HRK	Histidine kinase
E5206_16610	ENOG4105DY9	regulatoR
E5206_16630	ENOG4105KNE	Phosphatidate cytidylyltransferase
E5206_16635	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
E5206_16640	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
E5206_16645	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
E5206_16650	ENOG4105CE9	30S ribosomal protein S2
E5206_16660	ENOG4105C1G	acyl-Coa dehydrogenase
E5206_16670	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
E5206_16680	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
E5206_16690	ENOG4105C2C	drug resistance transporter, Bcr CflA
E5206_16710	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
E5206_16715	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
E5206_16750	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
E5206_16765	ENOG4105FBA	Phospholipase Carboxylesterase
E5206_16780	ENOG4105DWV	Homoserine O-trans-acetylase
E5206_16785	ENOG4108IQK	o-acetylhomoserine
E5206_16815	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
E5206_16825	ENOG4105CI2	imidazolone-5-propionate hydrolase
E5206_16835	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
E5206_16840	ENOG4105CPQ	Dehydrogenase
E5206_16860	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
E5206_16865	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
E5206_16870	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
E5206_16875	ENOG4105D4T	Citrate transporter
E5206_16880	ENOG4106F60	Histidine kinase
E5206_16905	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
E5206_16910	ENOG4108ZF3	Phosphatase
E5206_16925	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
E5206_16930	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
E5206_16935	ENOG4105D8K	carboxyl transferase
E5206_16950	ENOG4108ETY	sodium dicarboxylate symporter
E5206_16965	ENOG4105EYF	MMPL domain protein
E5206_16975	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
E5206_16980	ENOG4107WR6	Maf-like protein
E5206_16985	ENOG4108JIK	carboxylase
E5206_17010	ENOG4105CSH	Transporter
E5206_17015	ENOG4107QND	Nitrite extrusion protein
E5206_17020	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
E5206_17070	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
E5206_17080	ENOG4107QZF	nitrite reductase NADPH large subunit
E5206_17100	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
E5206_17110	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
E5206_17135	ENOG4107R8N	Glycosyl transferase, family 2
E5206_17150	ENOG4108NNZ	chitinase
E5206_17160	ENOG4108IAJ	Nad-dependent epimerase dehydratase
E5206_17165	ENOG4107QQG	Dehydrogenase
E5206_17170	ENOG4108UNV	SUF system FeS assembly protein, NifU family
E5206_17190	ENOG4105WH1	Two component transcriptional regulator luxr family
E5206_17200	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
E5206_17205	ENOG4107XT7	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
E5206_17215	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
E5206_17225	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
E5206_17235	ENOG4105CHR	reductase
E5206_17240	ENOG41067SE	Tetr family transcriptional regulator
E5206_17245	ENOG4105C5H	ABC transporter
E5206_17250	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
E5206_17255	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
E5206_17260	ENOG4106839	domain protein
E5206_17265	ENOG4105F8V	Hydrolase, tatD family
E5206_17270	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
E5206_17280	ENOG4105F8C	transglutaminase domain-containing protein
E5206_17310	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
E5206_17335	ENOG4107RGC	Glycosyl transferase, family 2
E5206_17340	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
E5206_17355	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
E5206_17360	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
E5206_17365	ENOG4108KGH	TRANSCRIPTIONal
E5206_17370	ENOG4105EIP	mannose-6-phosphate isomerase
E5206_17395	ENOG4108V9Q	carbonic anhydrase
E5206_17400	ENOG4105C9Q	fumarate hydratase class II
E5206_17430	ENOG4108IAB	Phoh family
E5206_17435	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
E5206_17440	ENOG4108UT2	hemolysin iii
E5206_17445	ENOG4105C7Z	Conserved Protein
E5206_17455	ENOG4105T1M	mycothiol conjugate amidase mca
E5206_17465	ENOG4107YD5	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
E5206_17475	ENOG4105C7B	Threonine dehydratase
E5206_17485	ENOG4107WI4	Aldose-1-epimerase
E5206_17490	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
E5206_17495	ENOG4105CHU	acetyl-coa acetyltransferase
E5206_17505	ENOG4105C32	Amino acid ABC transporter (Permease)
E5206_17510	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
E5206_17515	ENOG4105C0Z	ABC transporter
E5206_17520	ENOG4108IV0	ABC, transporter
E5206_17560	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
E5206_17565	ENOG4105DXN	mazG family
E5206_17570	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
E5206_17575	ENOG4107XFB	conserved TRANSMEMBRANE PROTEIN
E5206_17600	ENOG4105UIB	(ABC) transporter
E5206_17605	ENOG4108JQ9	ABC transporter
E5206_17610	ENOG4105DIH	basic membrane
E5206_17615	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
E5206_17620	ENOG4108ZHJ	Organic hydroperoxide resistance protein
E5206_17625	ENOG4105K56	Transcriptional regulator
E5206_17630	ENOG4107RM1	amidohydrolase
E5206_17655	ENOG4105E33	succinate dehydrogenase
E5206_17675	ENOG4105C31	Tryptophanyl-tRNA synthetase
E5206_17690	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
E5206_17710	ENOG4108Z0R	Transferase
E5206_17720	ENOG4105CUB	amino acid
E5206_17740	ENOG4105C2J	ABC transporter
E5206_17745	ENOG41062B0	ABC transporter, permease
E5206_17750	ENOG4105DFW	ABC transporter
E5206_17760	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
E5206_17770	ENOG4105D9P	serine threonine protein kinase
E5206_17780	ENOG4105E9K	Isocitrate dehydrogenase
E5206_17785	ENOG4105DC1	bifunctional purine biosynthesis protein purh
E5206_17790	ENOG41079KZ	Major Facilitator Superfamily
E5206_17830	ENOG4105DZ6	Band 7 protein
E5206_17845	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
E5206_17890	ENOG4105VEQ	Cold shock protein
E5206_17915	ENOG4105E7D	Protein of unknown function (DUF3375)
E5206_17945	ENOG4105F95	Monooxygenase
E5206_17950	ENOG4107RR1	TRANSCRIPTIONal
E5206_17965	ENOG4107UNZ	domain protein
E5206_18000	ENOG4105D7K	pfkb domain protein
E5206_18005	ENOG4105C2J	ABC transporter
E5206_18010	ENOG4105CNN	ABC, transporter
E5206_18015	ENOG4107R5G	Periplasmic binding protein LacI transcriptional regulator
E5206_18045	ENOG4105NAE	bifunctional deaminase-reductase domain protein
E5206_18065	ENOG4105C9B	Cysteine desulfurase
E5206_18075	ENOG41067HS	methyltransferase
E5206_18080	ENOG4108V75	Glutamine amidotransferase
E5206_18085	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
E5206_18095	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E5206_18105	ENOG41080V3	Major Facilitator superfamily
E5206_18140	ENOG4105C9U	ATP-dependent DNA helicase RecQ
E5206_18145	ENOG4105ERH	Fumarylacetoacetate hydrolase
E5206_18150	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
E5206_18160	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
E5206_18170	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
E5206_18175	ENOG4108MRH	transcriptional regulatory protein
E5206_18190	ENOG4105EFA	4-hydroxyphenylacetate
E5206_18205	ENOG4105EBR	Carboxylesterase
E5206_18220	ENOG4105D7T	ABC transporter
E5206_18225	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
E5206_18240	ENOG4105C26	Dehydrogenase
E5206_18260	ENOG4105CPU	Monooxygenase
E5206_18265	ENOG4105CSH	Transporter
E5206_18275	ENOG41086X7	Acylphosphatase
E5206_18285	ENOG4108IUX	(ABC) transporter
E5206_18335	ENOG4108535	NAD dependent epimerase/dehydratase family
E5206_18370	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
E5206_18385	ENOG4105Q56	cytochrome P450
E5206_18400	ENOG4108IG5	Transcriptional regulator
E5206_18415	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
E5206_18440	ENOG4105CMD	Transcriptional regulator, GntR family
E5206_18470	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
E5206_18505	ENOG4105C7K	acetolactate synthase
E5206_18525	ENOG4108JCI	Transcriptional regulator
E5206_18565	ENOG4108Z86	Glutamine amidotransferase
E5206_18570	ENOG4105CK5	oxidoreductase
E5206_18575	ENOG4105CK5	oxidoreductase
E5206_18580	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
E5206_18585	ENOG4105C2J	ABC transporter
E5206_18590	ENOG41062B0	ABC transporter, permease
E5206_18600	ENOG4108X79	transcriptional regulator
E5206_18605	ENOG4105DH8	myo-inositol catabolism
E5206_18610	ENOG4105F27	Major Facilitator
E5206_18615	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
E5206_18620	ENOG4105F0H	myo-inositol catabolism protein
E5206_18625	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
E5206_18635	ENOG4105C26	Dehydrogenase
E5206_18640	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
E5206_18650	ENOG4105D7K	pfkb domain protein
E5206_18655	ENOG41090U3	tautomerase
E5206_18660	ENOG4105NPE	arsR family transcriptional regulator
E5206_18675	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
E5206_18685	ENOG4105ECY	inositol monophosphatase
E5206_18700	ENOG4105BZU	Histidine kinase
E5206_18715	ENOG4108NNZ	chitinase
E5206_18735	ENOG4105PTV	Nudix Hydrolase
E5206_18740	ENOG4105BZ1	(ABC) transporter
E5206_18745	ENOG4105C5H	ABC transporter
E5206_18770	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
E5206_18775	ENOG4105CEV	competence damage-inducible protein
E5206_18800	ENOG4105DR5	peptidase
E5206_18810	ENOG4107R8H	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
E5206_18815	ENOG4107Y80	Major Facilitator superfamily
E5206_18825	ENOG4105VEQ	Cold shock protein
E5206_18850	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
E5206_18855	ENOG4105BZU	Histidine kinase
E5206_18870	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
E5206_18880	ENOG4105VEQ	Cold shock protein
E5206_18895	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
E5206_18915	ENOG4105KAV	tspo and mbr like protein
E5206_18925	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
E5206_18930	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
E5206_18935	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
E5206_18940	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
E5206_18950	ENOG4105C57	major facilitator superfamily
E5206_18955	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
E5206_18980	ENOG4105C54	Major Facilitator superfamily
E5206_19000	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
E5206_19010	ENOG4108IJ9	(ABC) transporter
E5206_19020	ENOG4105CQB	FAD linked oxidase domain protein
E5206_19045	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
E5206_19055	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
E5206_19090	ENOG4105C8N	cysteinyl-tRNA synthetase
E5206_19100	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
E5206_19105	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
E5206_19125	ENOG4105BZU	Histidine kinase
E5206_19135	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)