locus-tag	class	description
ART_0007	ENOG4105DSU	hydrolase
ART_0010	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
ART_0011	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
ART_0012	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
ART_0018	ENOG4105KME	endoribonuclease L-psp
ART_0019	ENOG4107258	Transcriptional regulator
ART_0027	ENOG4105CR4	methylisocitrate lyase
ART_0030	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
ART_0031	ENOG4105N14	lysine exporter protein LysE YggA
ART_0039	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
ART_0040	ENOG4108IG5	Transcriptional regulator
ART_0044	ENOG4107QQR	Sporulation
ART_0046	ENOG4108FUT	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
ART_0047	ENOG4105QE3	oxidoreductase
ART_0048	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
ART_0050	ENOG4105CIB	oxidoreductase Domain protein
ART_0052	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
ART_0054	ENOG4105ETE	Transcriptional regulator (LacI family
ART_0058	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
ART_0059	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
ART_0062	ENOG4105CAT	Cytidine monophosphate kinase
ART_0065	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
ART_0069	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
ART_0074	ENOG4107S1E	Beta-lactamase
ART_0077	ENOG4105CSU	acyl-Coa dehydrogenase
ART_0081	ENOG41083TI	Protein CrcB homolog
ART_0082	ENOG41083GQ	Protein CrcB homolog
ART_0086	ENOG4108UW8	fha domain-containing protein
ART_0091	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ART_0092	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
ART_0094	ENOG4105DKQ	ROK family
ART_0098	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
ART_0100	ENOG41068JE	domain protein
ART_0103	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
ART_0106	ENOG4108V6E	Cell division protein mraZ
ART_0107	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
ART_0109	ENOG4105CJN	penicillin-binding protein
ART_0112	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
ART_0113	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
ART_0115	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
ART_0116	ENOG4105DFU	Cell wall formation (By similarity)
ART_0118	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
ART_0119	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
ART_0120	ENOG4105DFA	alanine racemase domain protein
ART_0121	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
ART_0123	ENOG4107VQS	DivIVA family
ART_0125	ENOG4107ZIW	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
ART_0129	ENOG4105C0B	DNA polymerase III (alpha subunit)
ART_0131	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
ART_0132	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
ART_0133	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
ART_0137	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
ART_0138	ENOG4105C5F	glutamine synthetase
ART_0139	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
ART_0141	ENOG4105CBG	Sulfatase
ART_0142	ENOG4105E5Q	amino acid AbC transporter
ART_0143	ENOG4105CDA	abc transporter atp-binding protein
ART_0144	ENOG4105CSV	Glutaminase
ART_0196	ENOG4105CDU	Replicative dna helicase
ART_0204	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
ART_0208	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
ART_0209	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
ART_0216	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
ART_0217	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
ART_0219	ENOG4105FCD	Major Facilitator
ART_0222	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
ART_0223	ENOG4105WH1	Two component transcriptional regulator luxr family
ART_0226	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
ART_0227	ENOG4105D0M	Protease HtpX homolog
ART_0229	ENOG4105C4M	(Ubiquinol oxidase) subunit I
ART_0230	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
ART_0231	ENOG4108JJ9	ABC, transporter
ART_0235	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
ART_0242	ENOG4107ZFB	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
ART_0247	ENOG4107VEG	TrkA-N domain protein
ART_0248	ENOG4105C0X	amino acid
ART_0249	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
ART_0251	ENOG4107QM5	aconitate hydratase
ART_0256	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
ART_0259	ENOG4105CPC	Aldo Keto reductase
ART_0261	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
ART_0262	ENOG4105CHU	acetyl-coa acetyltransferase
ART_0263	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
ART_0269	ENOG4105E0X	reductase
ART_0272	ENOG4108Z66	YbaK ebsC protein
ART_0275	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
ART_0278	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
ART_0279	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
ART_0281	ENOG4105DJV	ribulose-phosphate 3-epimerase
ART_0286	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
ART_0287	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
ART_0288	ENOG4105M0N	phosphoribosyl-ATP pyrophosphatase
ART_0289	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
ART_0290	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
ART_0292	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
ART_0296	ENOG4105DK0	Indole-3-glycerol phosphate synthase
ART_0297	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
ART_0298	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
ART_0299	ENOG4107TBN	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
ART_0300	ENOG4105CBC	glutamate synthase
ART_0303	ENOG4105F9F	transposase
ART_0313	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
ART_0319	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
ART_0322	ENOG4106PVI	ATP-dependent carboxylate-amine ligase (By similarity)
ART_0335	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
ART_0337	ENOG4108HHA	Transketolase
ART_0339	ENOG4105CPP	Dehydrogenase, E1 component
ART_0340	ENOG4108JYK	Dehydrogenase
ART_0343	ENOG4105E33	succinate dehydrogenase
ART_0346	ENOG4105C5I	Dehydrogenase
ART_0353	ENOG4107QRI	Phosphoketolase
ART_0354	ENOG4108YV4	Universal stress protein
ART_0378	ENOG4105CB2	alcohol dehydrogenase
ART_0385	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
ART_0395	ENOG4105DQ4	alcohol dehydrogenase
ART_0404	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
ART_0413	ENOG4108W6C	Dehydrogenase
ART_0414	ENOG4105H3G	oxidoreductase
ART_0416	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
ART_0417	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
ART_0419	ENOG4105EWV	Sodium calcium exchanger membrane region
ART_0420	ENOG4108HYG	acetyltransferase
ART_0435	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
ART_0438	ENOG4105E9Z	Nad-dependent epimerase dehydratase
ART_0439	ENOG4105CPC	Aldo Keto reductase
ART_0442	ENOG4105CH2	amidohydrolase
ART_0443	ENOG4105D7V	transposase
ART_0445	ENOG4105CH2	amidohydrolase
ART_0448	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
ART_0451	ENOG4105NAE	bifunctional deaminase-reductase domain protein
ART_0456	ENOG4105CEY	Amp-dependent synthetase and ligase
ART_0459	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
ART_0460	ENOG4105BZU	Histidine kinase
ART_0461	ENOG4105WH1	Two component transcriptional regulator luxr family
ART_0466	ENOG4105WH1	Two component transcriptional regulator luxr family
ART_0476	ENOG4105BZ1	(ABC) transporter
ART_0477	ENOG4105BZ1	(ABC) transporter
ART_0486	ENOG4107RRE	RNA-directed DNA polymerase
ART_0488	ENOG4105CPC	Aldo Keto reductase
ART_0489	ENOG4105CPC	Aldo Keto reductase
ART_0494	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
ART_0502	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
ART_0511	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
ART_0513	ENOG4105KI2	Urea amidohydrolase subunit beta
ART_0514	ENOG4105CQM	Urea amidohydrolase subunit alpha
ART_0515	ENOG4105HFU	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
ART_0516	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
ART_0517	ENOG4107S16	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
ART_0518	ENOG4105ICD	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
ART_0519	ENOG4105D9G	High-affinity
ART_0523	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
ART_0526	ENOG4108IQI	permease
ART_0527	ENOG4107WHG	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
ART_0529	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
ART_0530	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
ART_0531	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
ART_0533	ENOG4105CPU	Monooxygenase
ART_0536	ENOG4105DFW	ABC transporter
ART_0537	ENOG4105C2J	ABC transporter
ART_0538	ENOG4107RNG	ABC transporter
ART_0539	ENOG4106N3A	copper homeostasis protein cutc
ART_0545	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
ART_0554	ENOG4108IXY	short-chain dehydrogenase reductase
ART_0557	ENOG4105WH1	Two component transcriptional regulator luxr family
ART_0558	ENOG41080VW	acetyltransferase
ART_0561	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
ART_0562	ENOG4105PMW	Domain of unknown function (DUF1990)
ART_0565	ENOG4105BZ1	(ABC) transporter
ART_0567	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
ART_0570	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
ART_0573	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
ART_0593	ENOG4105JSC	dimethylmenaquinone methyltransferase
ART_0601	ENOG4105F27	Major Facilitator
ART_0602	ENOG4106NZI	LysR family Transcriptional regulator
ART_0614	ENOG4105WH1	Two component transcriptional regulator luxr family
ART_0618	ENOG4105RHY	Pfam:UPF0157
ART_0620	ENOG4105EKQ	RNA-directed DNA polymerase
ART_0624	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
ART_0639	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
ART_0640	ENOG41084HI	prevent-host-death family
ART_0641	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
ART_0647	ENOG4107QM5	aconitate hydratase
ART_0649	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
ART_0651	ENOG4108VW9	Membrane
ART_0655	ENOG4105Q70	
ART_0656	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
ART_0657	ENOG4105EFZ	amidohydrolase
ART_0658	ENOG4105CQR	helicase
ART_0659	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
ART_0666	ENOG4105DVV	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine (By similarity)
ART_0667	ENOG4105F7N	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
ART_0668	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
ART_0670	ENOG4105WFD	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation (By similarity)
ART_0671	ENOG4105E5F	proteasome
ART_0672	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
ART_0675	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
ART_0678	ENOG4105C8N	cysteinyl-tRNA synthetase
ART_0679	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
ART_0680	ENOG4105CPC	Aldo Keto reductase
ART_0684	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
ART_0688	ENOG4105CHR	reductase
ART_0689	ENOG4105CHU	acetyl-coa acetyltransferase
ART_0692	ENOG4107QPH	glycogen) synthase
ART_0693	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
ART_0696	ENOG4107ZR7	Membrane
ART_0699	ENOG4105DF9	Lipoate-protein, ligase
ART_0700	ENOG4105NRA	50s ribosomal protein l31 type b
ART_0702	ENOG4105C2N	RNA methyltransferase TrmH family group 3
ART_0704	ENOG4105DKW	ABC transporter
ART_0705	ENOG4105EAC	phosphoserine phosphatase
ART_0706	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
ART_0708	ENOG4105CHR	reductase
ART_0713	ENOG4105C5H	ABC transporter
ART_0714	ENOG4107ZYJ	bioY protein
ART_0715	ENOG4108JJB	ABC transporter
ART_0716	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
ART_0717	ENOG4105CHU	acetyl-coa acetyltransferase
ART_0718	ENOG4107F3J	Amp-dependent synthetase and ligase
ART_0720	ENOG4105VG1	fes assembly suf system protein
ART_0721	ENOG4105C3K	feS assembly ATPase SufC
ART_0730	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
ART_0732	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
ART_0733	ENOG4105C89	phosphohexose isomerase
ART_0736	ENOG4107XU2	6-phosphogluconolactonase (EC 3.1.1.31)
ART_0738	ENOG4105CP7	Triose-phosphate isomerase
ART_0739	ENOG4105BZA	Phosphoglycerate kinase
ART_0740	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
ART_0742	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
ART_0743	ENOG4105CIE	May be required for sporulation (By similarity)
ART_0744	ENOG4105CHW	UPF0052 protein
ART_0745	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
ART_0746	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
ART_0748	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
ART_0749	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
ART_0756	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
ART_0760	ENOG4107QM2	Aldo Keto reductase
ART_0762	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
ART_0764	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
ART_0765	ENOG4105DNP	FAD linked oxidase domain protein
ART_0766	ENOG4107SM8	Adenylate Guanylate cyclase
ART_0767	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
ART_0768	ENOG4105KAF	membrAne
ART_0771	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
ART_0776	ENOG4105KA0	thioesterase Superfamily protein
ART_0779	ENOG4105EUB	pirin domain protein
ART_0784	ENOG4105CEY	Amp-dependent synthetase and ligase
ART_0785	ENOG4105Y3U	Transglycosylase-associated protein
ART_0788	ENOG4105D8V	Glucose sorbosone dehydrogenase
ART_0792	ENOG41060NJ	transcriptional regulator
ART_0796	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
ART_0799	ENOG4105BZ4	penicillin-binding protein
ART_0800	ENOG4105DFA	alanine racemase domain protein
ART_0801	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
ART_0802	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
ART_0804	ENOG4105CQ7	ATP-dependent helicase
ART_0807	ENOG4105C7B	Threonine dehydratase
ART_0813	ENOG4105DZ6	Band 7 protein
ART_0817	ENOG4105WH1	Two component transcriptional regulator luxr family
ART_0826	ENOG4105E3B	Multicopper oxidase
ART_0831	ENOG4108ESY	Metal dependent phosphohydrolase
ART_0840	ENOG4107QUV	Domain protein
ART_0841	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
ART_0847	ENOG4107UWC	ABC, transporter
ART_0848	ENOG4105CBG	Sulfatase
ART_0850	ENOG4105EEQ	Na H antiporter
ART_0855	ENOG4105DIK	(ABC) transporter
ART_0859	ENOG4105CBG	Sulfatase
ART_0861	ENOG4105DRS	transport system, permease
ART_0864	ENOG4105CMD	Transcriptional regulator, GntR family
ART_0872	ENOG4108I0Q	anthranilate phosphoribosyltransferase
ART_0873	ENOG4105CCU	oxidase (Subunit III)
ART_0874	ENOG4107UDY	cytochrome C
ART_0875	ENOG4107EUI	c reductase, iron-sulfur
ART_0876	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
ART_0878	ENOG4105FDP	GntR family transcriptional regulator
ART_0880	ENOG4108ZRS	Part of cytochrome c oxidase, its function is
ART_0881	ENOG4105BZ9	Cytochrome C oxidase, subunit I
ART_0882	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
ART_0886	ENOG4105CPC	Aldo Keto reductase
ART_0887	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
ART_0890	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
ART_0891	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
ART_0892	ENOG4107QXN	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
ART_0893	ENOG4105C9K	Endothelin-converting enzyme 1
ART_0895	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
ART_0897	ENOG4107VNR	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
ART_0901	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
ART_0902	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
ART_0905	ENOG4105CSA	Coproporphyrinogen iii oxidase
ART_0906	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
ART_0908	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
ART_0910	ENOG4105BZP	glycoside hydrolase 15-related
ART_0911	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
ART_0918	ENOG4105DIA	mandelate racemase muconate lactonizing
ART_0929	ENOG41067RQ	csbd family
ART_0934	ENOG4105EPR	degv family
ART_0935	ENOG4105C8T	Leucyl-tRNA synthetase
ART_0936	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
ART_0937	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
ART_0939	ENOG4107RHR	regulatoR
ART_0940	ENOG4105CV8	reductase
ART_0945	ENOG4107RSZ	Primosomal protein n'
ART_0946	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
ART_0948	ENOG4105MTQ	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
ART_0949	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
ART_0950	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
ART_0951	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
ART_0952	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
ART_0953	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
ART_0955	ENOG4105CD3	dihydroorotase
ART_0956	ENOG4105CXT	aspartate transcarbamylase
ART_0957	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
ART_0959	ENOG410803B	Involved in the transcription termination process (By similarity)
ART_0960	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
ART_0962	ENOG4105D49	3-dehydroquinate synthase
ART_0963	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
ART_0964	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
ART_0965	ENOG4105E2X	shikimate dehydrogenase
ART_0967	ENOG41080G3	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
ART_0968	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
ART_0971	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
ART_0976	ENOG4105C9M	aspartyl-trna synthetase
ART_0977	ENOG4105CUT	histidyl-tRNA synthetase
ART_0979	ENOG4105C99	atpase involved in dna repair
ART_0981	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
ART_0982	ENOG4107RTU	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
ART_0985	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
ART_0986	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
ART_0987	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
ART_0988	ENOG4105CDY	transcriptional regulatory protein
ART_0989	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
ART_0990	ENOG4105CAQ	asparagine synthetase
ART_0991	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
ART_0992	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
ART_0993	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
ART_0994	ENOG4108VTU	Cdp-alcohol phosphatidyltransferase
ART_0996	ENOG4105C22	threonyL-tRNA synthetase
ART_0997	ENOG4105C0B	DNA polymerase III (alpha subunit)
ART_0999	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
ART_1001	ENOG4108RAV	Conserved protein
ART_1002	ENOG4105C31	Tryptophanyl-tRNA synthetase
ART_1010	ENOG4105CEY	Amp-dependent synthetase and ligase
ART_1012	ENOG4108Z12	YiaAB two helix domain-containing protein
ART_1013	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
ART_1014	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
ART_1015	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
ART_1018	ENOG4108RFG	Tetr family transcriptional regulator
ART_1019	ENOG4108UW5	maltose o-acetyltransferase
ART_1020	ENOG4105C5Q	Transcriptional regulator
ART_1021	ENOG4105C26	Dehydrogenase
ART_1026	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
ART_1027	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
ART_1028	ENOG4105K5B	UPF0225 protein
ART_1029	ENOG4105FDP	GntR family transcriptional regulator
ART_1032	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
ART_1034	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
ART_1036	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
ART_1040	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
ART_1041	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ART_1043	ENOG410826X	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
ART_1045	ENOG4105DWF	phosphomethylpyrimidine kinase
ART_1046	ENOG4105C03	ribonuclease
ART_1049	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
ART_1051	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
ART_1052	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
ART_1055	ENOG4105K78	MarR family Transcriptional regulator
ART_1057	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
ART_1059	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
ART_1060	ENOG4105BZF	Glycosyl transferase (Group 1
ART_1063	ENOG4105MC2	DSBA oxidoreductase
ART_1064	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
ART_1065	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
ART_1066	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
ART_1067	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
ART_1069	ENOG4108YZG	isomerase
ART_1074	ENOG4105D8X	mechanosensitive ion channel
ART_1078	ENOG4105C29	acyl-CoA thioesterase
ART_1088	ENOG4108ZHJ	Organic hydroperoxide resistance protein
ART_1089	ENOG4105K56	Transcriptional regulator
ART_1092	ENOG4105DQ4	alcohol dehydrogenase
ART_1095	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
ART_1098	ENOG4105F6J	Alpha beta hydrolase fold
ART_1104	ENOG4105WH1	Two component transcriptional regulator luxr family
ART_1109	ENOG4105H3G	oxidoreductase
ART_1112	ENOG4105CVK	Glutamate decarboxylase
ART_1115	ENOG41090CE	integral membrane protein
ART_1117	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
ART_1121	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
ART_1122	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
ART_1127	ENOG4107XFJ	UPF0246 protein
ART_1128	ENOG4105HRU	Glyoxalase Bleomycin resistance protein (Dioxygenase
ART_1130	ENOG4105EGD	dinuclear metal center protein, YbgI family
ART_1131	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
ART_1133	ENOG4105D7W	serine acetyltransferase
ART_1136	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
ART_1137	ENOG4105CPQ	Dehydrogenase
ART_1138	ENOG4105CHR	reductase
ART_1139	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
ART_1142	ENOG4108N16	Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region
ART_1144	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
ART_1148	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
ART_1151	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
ART_1152	ENOG41082KT	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
ART_1155	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
ART_1156	ENOG4108KGH	TRANSCRIPTIONal
ART_1158	ENOG4105C0P	Mg chelatase subunit ChlI
ART_1159	ENOG41080R2	UPF0102 protein
ART_1161	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
ART_1163	ENOG4107QYR	Signal peptidase i
ART_1164	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
ART_1165	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
ART_1166	ENOG4107XUM	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
ART_1167	ENOG41082KU	UPF0109 protein
ART_1168	ENOG4105K5M	30s ribosomal protein S16
ART_1171	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
ART_1172	ENOG4105XYF	acetyltransferase
ART_1178	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
ART_1185	ENOG4107QNK	)-transporter
ART_1188	ENOG4105E2T	synthase III
ART_1189	ENOG410680H	amp-dependent synthetase and ligase
ART_1190	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
ART_1194	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
ART_1196	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
ART_1197	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
ART_1198	ENOG41062IY	50S ribosomal protein L32
ART_1201	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
ART_1207	ENOG4106H78	methyltransferase
ART_1208	ENOG4105CB5	ATP-dependent DNA helicase recG
ART_1217	ENOG41085FC	arsR family transcriptional regulator
ART_1224	ENOG4105CGP	Urocanate hydratase
ART_1226	ENOG4105NFY	transcriptional modulator of maze toxin, mazf
ART_1227	ENOG4105C1G	acyl-Coa dehydrogenase
ART_1228	ENOG4105ETS	cytosine purines uracil thiamine allantoin
ART_1229	ENOG4105CIH	Imidazole acetol-phosphate transaminase
ART_1231	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
ART_1233	ENOG4105NTW	Transcriptional regulator
ART_1243	ENOG4105CPK	Glycosyl transferase (Group 1
ART_1245	ENOG4107VDP	teichoic acid biosynthesis
ART_1249	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
ART_1250	ENOG4107SJB	teichoic acid biosynthesis
ART_1251	ENOG4108NMT	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon (By similarity)
ART_1255	ENOG4108UW5	maltose o-acetyltransferase
ART_1256	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
ART_1259	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
ART_1260	ENOG4107SJB	teichoic acid biosynthesis
ART_1263	ENOG4107SJB	teichoic acid biosynthesis
ART_1263	ENOG4107SJB	teichoic acid biosynthesis
ART_1266	ENOG4105EY8	ABC transporter
ART_1271	ENOG4108KGH	TRANSCRIPTIONal
ART_1273	ENOG4105ETE	Transcriptional regulator (LacI family
ART_1275	ENOG4105CE4	GlcNAc 6-P deacetylase
ART_1276	ENOG4108SU4	UPF0309 protein
ART_1277	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
ART_1282	ENOG4105K64	Glycosyl transferase, family 2
ART_1284	ENOG4108IJ1	Dehydrogenase
ART_1288	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
ART_1293	ENOG4105CPF	Cell wall formation (By similarity)
ART_1294	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
ART_1296	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
ART_1301	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
ART_1302	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
ART_1303	ENOG41069M3	Transcriptional regulator
ART_1304	ENOG4105K4I	Scp-like extracellular
ART_1314	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
ART_1321	ENOG4105C85	amino acid
ART_1324	ENOG4105WH1	Two component transcriptional regulator luxr family
ART_1325	ENOG4105BZU	Histidine kinase
ART_1327	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
ART_1328	ENOG4105S64	Formate nitrite transporter
ART_1330	ENOG4105CM2	brancheD-chain amino acid aminotransferase
ART_1333	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
ART_1334	ENOG4105BZU	Histidine kinase
ART_1335	ENOG4105WH1	Two component transcriptional regulator luxr family
ART_1337	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
ART_1338	ENOG4105XN3	extracellular solute-binding protein family 1
ART_1340	ENOG41073TP	transcriptional regulator
ART_1344	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
ART_1345	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
ART_1349	ENOG4105CHR	reductase
ART_1350	ENOG4108JQ1	Dehydrogenase
ART_1352	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
ART_1357	ENOG4106N3A	copper homeostasis protein cutc
ART_1359	ENOG41061MV	Arylsulfatase
ART_1360	ENOG4105DKQ	ROK family
ART_1362	ENOG4105DRS	transport system, permease
ART_1363	ENOG4105S9S	Binding-protein-dependent transport systems, inner membrane component
ART_1365	ENOG41061DF	Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity)
ART_1368	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
ART_1369	ENOG4108ZP8	Acetolactate synthase small subunit
ART_1371	ENOG4105C01	Dihydroxy-acid dehydratase
ART_1373	ENOG4105EYW	Ion transport protein
ART_1376	ENOG4105DEF	Extracellular solute-binding protein, family 5
ART_1377	ENOG4105DWT	malate dehydrogenase (quinone)
ART_1381	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
ART_1382	ENOG410834F	Transcriptional regulator
ART_1386	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
ART_1387	ENOG4105ERH	Fumarylacetoacetate hydrolase
ART_1391	ENOG4105BZU	Histidine kinase
ART_1396	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
ART_1397	ENOG4108IYU	L-aspartate oxidase
ART_1398	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
ART_1400	ENOG4105C85	amino acid
ART_1403	ENOG4105EYH	Exonuclease
ART_1404	ENOG4107RH8	nuclease SbcCD subunit D
ART_1408	ENOG4105VG5	Membrane
ART_1416	ENOG4105DVE	abc transporter atp-binding protein
ART_1417	ENOG4105FDP	GntR family transcriptional regulator
ART_1418	ENOG4105DQR	SNARE associated Golgi
ART_1419	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
ART_1420	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
ART_1423	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
ART_1425	ENOG4105KEN	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
ART_1426	ENOG4107RKP	Nicotinate phosphoribosyltransferase
ART_1427	ENOG4108RWI	nicotinamidase
ART_1430	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
ART_1433	ENOG41080RH	Thioredoxin
ART_1438	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
ART_1439	ENOG4105CE4	GlcNAc 6-P deacetylase
ART_1440	ENOG4105FF5	Membrane
ART_1443	ENOG410825K	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
ART_1444	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
ART_1445	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
ART_1446	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
ART_1447	ENOG4108T62	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
ART_1448	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
ART_1449	ENOG4106DE0	ATP synthase
ART_1450	ENOG4107UH5	it plays a direct role in the translocation of protons across the membrane (By similarity)
ART_1452	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
ART_1455	ENOG4108MKI	Glycosyl transferase, family 2
ART_1457	ENOG4107UIY	sua5 ycio yrdc ywlc family protein
ART_1458	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
ART_1459	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
ART_1461	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
ART_1462	ENOG4107R5I	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
ART_1463	ENOG4105D6E	homoserine dehydrogenase
ART_1464	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
ART_1465	ENOG4105C75	arginyL-tRNA synthetase
ART_1469	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
ART_1471	ENOG4105ETS	cytosine purines uracil thiamine allantoin
ART_1477	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
ART_1478	ENOG4105EBR	Carboxylesterase
ART_1481	ENOG4107258	Transcriptional regulator
ART_1483	ENOG4105CSH	Transporter
ART_1484	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
ART_1489	ENOG4105EJQ	L-serine dehydratase
ART_1491	ENOG410870W	N-acetyltransferase
ART_1492	ENOG4108KTG	Membrane protein, drug metabolite transporter
ART_1493	ENOG41067TZ	transcriptional regulator, MarR family
ART_1495	ENOG4105CQ7	ATP-dependent helicase
ART_1496	ENOG4105VTW	prevent-host-death family
ART_1497	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
ART_1501	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
ART_1502	ENOG4105D7V	transposase
ART_1503	ENOG4107ZUX	Histidine triad (HIT) protein
ART_1504	ENOG4105DQ4	alcohol dehydrogenase
ART_1505	ENOG4105KHC	sulfurtransferase
ART_1506	ENOG4105C6T	cysteine synthase
ART_1507	ENOG4105E8R	UPF0173 metal-dependent hydrolase
ART_1511	ENOG4105E0A	ABC, transporter
ART_1512	ENOG4105DSE	periplasmic solute binding protein
ART_1514	ENOG4105C37	(CBS) domain
ART_1516	ENOG4108Z4X	TRANSCRIPTIONal
ART_1517	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
ART_1518	ENOG4105JXH	GntR family transcriptional regulator
ART_1521	ENOG4105D56	permease protein
ART_1523	ENOG4105CXK	mandelate racemase muconate lactonizing
ART_1524	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
ART_1525	ENOG4105CXK	mandelate racemase muconate lactonizing
ART_1526	ENOG4105DEI	Mannitol dehydrogenase
ART_1527	ENOG4105D2H	Uronic isomerase
ART_1528	ENOG4105ETE	Transcriptional regulator (LacI family
ART_1531	ENOG4105DDC	Oxidoreductase domain protein
ART_1533	ENOG4105ETE	Transcriptional regulator (LacI family
ART_1534	ENOG4105ETE	Transcriptional regulator (LacI family
ART_1537	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
ART_1540	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
ART_1547	ENOG4105EMN	RNA polymerase sigma factor
ART_1549	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
ART_1551	ENOG4107TK4	histidinol-phosphate phosphatase
ART_1552	ENOG4105C9B	Cysteine desulfurase
ART_1555	ENOG4107R5H	iron (metal) dependent repressor, dtxr family
ART_1562	ENOG41061ZR	Transcriptional regulator
ART_1564	ENOG4105EJQ	L-serine dehydratase
ART_1631	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
ART_1634	ENOG4105CAK	Cell division ATP-binding protein ftsE
ART_1635	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
ART_1653	ENOG4105BZ1	(ABC) transporter
ART_1655	ENOG4107XB0	Lipopolysaccharide 1,2-N-acetylglucosaminetransferase
ART_1657	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
ART_1662	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
ART_1665	ENOG4108IJ1	Dehydrogenase
ART_1667	ENOG4105CMR	udp-glucose 4-epimerase
ART_1669	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
ART_1673	ENOG4105CKK	Glycosyl transferase, family 2
ART_1677	ENOG4105EXC	Acyl-transferase
ART_1679	ENOG4107QPT	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
ART_1681	ENOG4105EY8	ABC transporter
ART_1683	ENOG410602S	Transferase
ART_1686	ENOG4105EC2	ftsk spoIIIe
ART_1688	ENOG4105KRM	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
ART_1690	ENOG4105C7I	Dehydrogenase
ART_1697	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
ART_1698	ENOG4105T0Z	Conserved Protein
ART_1699	ENOG4108S7Q	sigma 54 modulation protein ribosomal protein S30ea
ART_1700	ENOG4105MJ2	Competence protein
ART_1702	ENOG4108T3R	lipoprotein lpqB
ART_1703	ENOG4105BZU	Histidine kinase
ART_1704	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ART_1708	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
ART_1715	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
ART_1719	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
ART_1723	ENOG4105EUJ	GTP cyclohydrolase i
ART_1725	ENOG4105EEI	dihydropteroate synthase
ART_1727	ENOG4105DVC	DnaJ domain protein
ART_1728	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
ART_1729	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
ART_1731	ENOG4105C10	Electron transfer flavoprotein
ART_1732	ENOG4105BZJ	Electron transfer flavoprotein
ART_1735	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
ART_1737	ENOG4105C0H	protease
ART_1741	ENOG41087YS	Phage shock protein A
ART_1742	ENOG4105CV8	reductase
ART_1743	ENOG4105X1Q	TOBE domain protein
ART_1751	ENOG4105C1G	acyl-Coa dehydrogenase
ART_1753	ENOG4105C10	Electron transfer flavoprotein
ART_1755	ENOG41067TZ	transcriptional regulator, MarR family
ART_1757	ENOG410846T	CoA-transferase family III
ART_1758	ENOG4105CEY	Amp-dependent synthetase and ligase
ART_1759	ENOG4105E39	Enoyl-CoA hydratase
ART_1760	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
ART_1761	ENOG4105CHU	acetyl-coa acetyltransferase
ART_1762	ENOG4105C1G	acyl-Coa dehydrogenase
ART_1763	ENOG41060WC	Enoyl-CoA hydratase
ART_1766	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
ART_1771	ENOG4107QX3	carboxylase
ART_1775	ENOG4105DSF	transport protein
ART_1778	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
ART_1779	ENOG4105CFC	Transporter
ART_1781	ENOG4107QWE	)-transporter
ART_1782	ENOG4105DJZ	UPF0182 protein
ART_1783	ENOG41063PX	domain protein
ART_1788	ENOG4105E09	nadh pyrophosphatase
ART_1796	ENOG4106TNF	Periplasmic binding protein
ART_1797	ENOG4105E5Q	amino acid AbC transporter
ART_1798	ENOG4105CDA	abc transporter atp-binding protein
ART_1802	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
ART_1806	ENOG4107QME	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
ART_1807	ENOG4107JTW	chlorite dismutase
ART_1809	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
ART_1810	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
ART_1813	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
ART_1814	ENOG4108UMI	ABC transporter, permease
ART_1815	ENOG4105D01	(LipO)protein
ART_1820	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
ART_1822	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
ART_1823	ENOG4107Y5I	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
ART_1824	ENOG4105CK7	Sodium proline symporter
ART_1825	ENOG4105C5R	Aminotransferase
ART_1832	ENOG4105DEN	Luciferase family
ART_1834	ENOG4105H3G	oxidoreductase
ART_1840	ENOG4108K01	transcriptional regulator
ART_1853	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
ART_1855	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
ART_1856	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
ART_1857	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
ART_1858	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ART_1861	ENOG4105D94	Major Facilitator Superfamily
ART_1862	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
ART_1868	ENOG4105C1J	atp-dependent rna helicase
ART_1871	ENOG4105DB7	PHP domain protein
ART_1872	ENOG4107T6F	Xaa-Pro aminopeptidase
ART_1874	ENOG4105CJW	magnesium transporter
ART_1878	ENOG4105UTW	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
ART_1879	ENOG4105DU6	RNA polymerase
ART_1883	ENOG4108R3E	Dna-3-methyladenine glycosylase i
ART_1885	ENOG4108URH	decarboxylase
ART_1886	ENOG4105CDA	abc transporter atp-binding protein
ART_1887	ENOG4107UBR	Extracellular solute-binding protein family 3
ART_1888	ENOG4108Q1T	ABC transporter
ART_1889	ENOG4105DRP	amino acid AbC transporter
ART_1890	ENOG4107R4C	succinyl-diaminopimelate desuccinylase
ART_1892	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
ART_1899	ENOG4108Z4U	Ferredoxin
ART_1903	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
ART_1904	ENOG4108JQ6	ABC transporter
ART_1905	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
ART_1906	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
ART_1907	ENOG4107QSI	ABC, transporter
ART_1908	ENOG4105CI3	gtp-binding protein typa
ART_1911	ENOG4108ZGX	Histidine kinase
ART_1913	ENOG4108M15	ABC transporter
ART_1917	ENOG4108NY6	Extracellular solute-binding protein, family 5
ART_1929	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
ART_1930	ENOG4105JXH	GntR family transcriptional regulator
ART_1931	ENOG41083X2	DNA polymerase III, epsilon subunit
ART_1937	ENOG4105C3G	gtp-binding protein
ART_1938	ENOG4105CGY	Dna recombination protein
ART_1940	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
ART_1942	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
ART_1943	ENOG4105YX8	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
ART_1945	ENOG4105CSR	polyphosphate kinase 2
ART_1949	ENOG4105ETE	Transcriptional regulator (LacI family
ART_1950	ENOG4105RD7	BadF BadG BcrA BcrD
ART_1951	ENOG4105EA8	2-Nitropropane dioxygenase
ART_1952	ENOG4105EW9	transcriptional regulator AsnC family
ART_1953	ENOG4105D7N	magnesium and cobalt transport protein CorA
ART_1956	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
ART_1958	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
ART_1959	ENOG4105E7W	lamb ycsf family protein
ART_1960	ENOG4105P4J	Allophanate hydrolase, subunit 1
ART_1964	ENOG4108X07	Tetr family transcriptional regulator
ART_1965	ENOG4105CIG	ABC transporter
ART_1969	ENOG4105BZ4	penicillin-binding protein
ART_1971	ENOG4105C5H	ABC transporter
ART_1986	ENOG4105C6F	GntR Family Transcriptional Regulator
ART_1989	ENOG4105C0D	helicase
ART_1991	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
ART_1993	ENOG4105EF1	ribulokinase
ART_1994	ENOG4105ETE	Transcriptional regulator (LacI family
ART_1996	ENOG4107WI4	Aldose-1-epimerase
ART_2011	ENOG4108F3G	Type I restriction-modification system, R subunit
ART_2025	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
ART_2026	ENOG41080UU	5-formyltetrahydrofolate cyclo-ligase
ART_2031	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
ART_2035	ENOG4107QVP	Dehydrogenase
ART_2041	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
ART_2043	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
ART_2044	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
ART_2050	ENOG4108IPW	abc transporter atp-binding protein
ART_2051	ENOG4105CM4	permease protein
ART_2055	ENOG4105F9E	Shikimate 5-dehydrogenase
ART_2056	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
ART_2057	ENOG410841Q	phosphoesterase PA-phosphatase related protein
ART_2059	ENOG4105ETX	regulatoR
ART_2060	ENOG4105BZU	Histidine kinase
ART_2063	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
ART_2064	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
ART_2066	ENOG4108097	ATP-binding protein
ART_2067	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
ART_2068	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
ART_2072	ENOG4105CG3	alpha amylase, catalytic region
ART_2074	ENOG4105CZA	synthase
ART_2076	ENOG4105CPC	Aldo Keto reductase
ART_2080	ENOG41082KK	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
ART_2081	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
ART_2082	ENOG4105CS9	pantothenic acid kinase
ART_2084	ENOG41080FJ	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
ART_2085	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
ART_2086	ENOG4108UJD	30S ribosomal protein S9
ART_2087	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
ART_2088	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
ART_2089	ENOG4108ZT0	50S ribosomal protein l17
ART_2090	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
ART_2091	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
ART_2092	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ART_2094	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
ART_2097	ENOG4105BZ7	extracellular solute-binding protein family 1
ART_2098	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
ART_2099	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
ART_2103	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
ART_2106	ENOG410849U	50S ribosomal protein L30
ART_2107	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
ART_2108	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
ART_2109	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
ART_2110	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
ART_2111	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ART_2112	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
ART_2113	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
ART_2114	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
ART_2115	ENOG41082SA	50s ribosomal protein l29
ART_2116	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
ART_2117	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
ART_2118	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
ART_2120	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
ART_2121	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
ART_2122	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
ART_2123	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
ART_2124	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
ART_2129	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
ART_2130	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
ART_2131	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
ART_2132	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
ART_2134	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
ART_2135	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
ART_2137	ENOG4105CHU	acetyl-coa acetyltransferase
ART_2139	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
ART_2140	ENOG4108VZM	50s ribosomal protein L10
ART_2143	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
ART_2144	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
ART_2145	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
ART_2146	ENOG410683Z	Preprotein translocase SecE subunit
ART_2149	ENOG4105WH1	Two component transcriptional regulator luxr family
ART_2157	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
ART_2159	ENOG4108X6U	May play a role in the intracellular transport of hydrophobic ligands
ART_2162	ENOG4107NHD	transcriptional regulator
ART_2163	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
ART_2164	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
ART_2169	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
ART_2173	ENOG4107QJH	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
ART_2176	ENOG4107R4N	Cell wall formation (By similarity)
ART_2179	ENOG410900P	UPF0336 protein
ART_2181	ENOG4105C57	major facilitator superfamily
ART_2186	ENOG4105CI0	Citrate lyase
ART_2197	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
ART_2198	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
ART_2199	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
ART_2200	ENOG4105DTD	Dehydrogenase
ART_2201	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
ART_2202	ENOG4105MS9	Resuscitation-promoting factor
ART_2204	ENOG4108Z4X	TRANSCRIPTIONal
ART_2211	ENOG4105C26	Dehydrogenase
ART_2217	ENOG4105CPQ	Dehydrogenase
ART_2218	ENOG4105IE8	Alpha-ketoglutarate permease
ART_2219	ENOG4105CMT	Dihydroxyacetone kinase
ART_2220	ENOG4107YVI	ribose 5-phosphate isomerase
ART_2221	ENOG4105CHR	reductase
ART_2223	ENOG41080RH	Thioredoxin
ART_2225	ENOG4105DXB	Major Facilitator superfamily
ART_2233	ENOG4108VPT	UPF0234 protein
ART_2236	ENOG4105BZU	Histidine kinase
ART_2237	ENOG4105GCF	PGAM
ART_2240	ENOG4105F9F	transposase
ART_2241	ENOG4105CH6	catalase
ART_2245	ENOG4105CUB	amino acid
ART_2250	ENOG4107QN2	dihydrolipoyl dehydrogenase
ART_2257	ENOG4105C26	Dehydrogenase
ART_2262	ENOG4105CZE	histidine utilization repressor
ART_2264	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
ART_2266	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
ART_2267	ENOG4108IY8	ABC, transporter
ART_2280	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
ART_2281	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
ART_2286	ENOG4108IUX	(ABC) transporter
ART_2287	ENOG4105EN6	Membrane
ART_2293	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
ART_2294	ENOG4105E4F	Isochorismate synthase
ART_2295	ENOG4106PMH	Extracellular solute-binding protein family 3
ART_2296	ENOG4108HW4	amino acid AbC transporter
ART_2298	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
ART_2299	ENOG4107TCW	O-succinylbenzoate synthase
ART_2306	ENOG4107TE5	Lipid kinase
ART_2309	ENOG4105CQB	FAD linked oxidase domain protein
ART_2312	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
ART_2313	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
ART_2314	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
ART_2315	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
ART_2316	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
ART_2322	ENOG4105DXM	phenylacetic acid degradation protein
ART_2323	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
ART_2324	ENOG4105E39	Enoyl-CoA hydratase
ART_2325	ENOG4105CHU	acetyl-coa acetyltransferase
ART_2331	ENOG4105CVK	Glutamate decarboxylase
ART_2332	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
ART_2333	ENOG4105C6K	Malic enzyme
ART_2340	ENOG4105C5H	ABC transporter
ART_2345	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
ART_2348	ENOG4105M2Z	protein tyrosine serine phosphatase
ART_2351	ENOG4107SIQ	Naphthoate synthase
ART_2363	ENOG4105CVR	type I restriction-modification system
ART_2374	ENOG4105KAK	Plasmid pRiA4b ORF-3 family protein
ART_2375	ENOG4105DFS	Conserved Protein
ART_2377	ENOG4105DZR	Type I site-specific deoxyribonuclease
ART_2378	ENOG4105E7D	Protein of unknown function (DUF3375)
ART_2387	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
ART_2394	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
ART_2397	ENOG4105C01	Dihydroxy-acid dehydratase
ART_2399	ENOG4108IUW	ABC transporter
ART_2400	ENOG4105CFH	Aspartokinase
ART_2401	ENOG4108JPW	Aminotransferase
ART_2402	ENOG4105C26	Dehydrogenase
ART_2405	ENOG4105C26	Dehydrogenase
ART_2408	ENOG4105CJP	fad dependent oxidoreductase
ART_2413	ENOG4105K56	Transcriptional regulator
ART_2422	ENOG410839H	phosphoribosylformylglycinamidine synthase
ART_2423	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
ART_2424	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
ART_2428	ENOG4105NAE	bifunctional deaminase-reductase domain protein
ART_2430	ENOG4105K4P	CoA-binding domain protein
ART_2433	ENOG4107QPI	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
ART_2435	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
ART_2436	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
ART_2438	ENOG4108QIU	Dehydrogenase
ART_2446	ENOG4105CEI	nitrite reductase
ART_2452	ENOG4107RCW	fructose-bisphosphate aldolase
ART_2457	ENOG4107104	thymidine kinase
ART_2458	ENOG4105BZ9	Cytochrome C oxidase, subunit I
ART_2459	ENOG4107104	thymidine kinase
ART_2460	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
ART_2462	ENOG4108UHU	Aldolase
ART_2463	ENOG4105CXK	mandelate racemase muconate lactonizing
ART_2464	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
ART_2465	ENOG4105HS6	binding-protein-dependent transport systems inner membrane Component
ART_2467	ENOG4107XBN	GntR Family Transcriptional Regulator
ART_2468	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
ART_2469	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
ART_2471	ENOG4108HQS	Glycine betaine
ART_2472	ENOG4108IJ7	Glycine betaine
ART_2475	ENOG4105ETE	Transcriptional regulator (LacI family
ART_2486	ENOG4105VBF	alkaline shock protein
ART_2488	ENOG4105K4H	Nlp p60 protein
ART_2494	ENOG4105JDN	Copper resistance protein
ART_2495	ENOG4105C7N	Xanthine uracil vitamin C permease
ART_2496	ENOG41088SP	formiminoglutamate hydrolase
ART_2499	ENOG4105C84	Histidine ammonia-lyase
ART_2502	ENOG4105C85	amino acid
ART_2506	ENOG41087PP	glycosyltransferase MGT family
ART_2511	ENOG4105BZP	glycoside hydrolase 15-related
ART_2512	ENOG4106BRA	Membrane
ART_2518	ENOG4105E98	transcriptional regulator DeoR family
ART_2519	ENOG4105DE4	1-phosphofructokinase
ART_2520	ENOG4105DM4	PTS System
ART_2521	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
ART_2522	ENOG410849S	phosphocarrier protein (HPr)
ART_2523	ENOG4105CSH	Transporter
ART_2524	ENOG4105EMU	Dehydrogenase
ART_2526	ENOG4105DWF	phosphomethylpyrimidine kinase
ART_2527	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
ART_2532	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
ART_2533	ENOG41081E8	Alpha beta hydrolase
ART_2540	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
ART_2543	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
ART_2547	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
ART_2555	ENOG4108UTZ	Dihydroxyacetone kinase
ART_2556	ENOG4105CMT	Dihydroxyacetone kinase
ART_2559	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
ART_2562	ENOG4105CRK	lysyL-tRNA synthetase
ART_2563	ENOG4105ETE	Transcriptional regulator (LacI family
ART_2564	ENOG4105DU0	nucleoside hydrolase
ART_2565	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
ART_2566	ENOG4108RVA	ribokinase
ART_2567	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
ART_2572	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ART_2575	ENOG4105EUJ	GTP cyclohydrolase i
ART_2576	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
ART_2579	ENOG4107RD1	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
ART_2585	ENOG4108KP7	hydrolase
ART_2586	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
ART_2587	ENOG4107TE5	Lipid kinase
ART_2589	ENOG4105C72	UPF0176 protein
ART_2590	ENOG4105DUX	Transporter
ART_2595	ENOG4105C2W	permease
ART_2598	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
ART_2599	ENOG4105DRR	Transcriptional regulator, GntR family
ART_2603	ENOG4105CTU	Proline racemase
ART_2607	ENOG4108IV0	ABC, transporter
ART_2608	ENOG4105C0Z	ABC transporter
ART_2609	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
ART_2610	ENOG4105C32	Amino acid ABC transporter (Permease)
ART_2611	ENOG4105CP9	extracellular ligand-binding receptor
ART_2612	ENOG4105BZW	Glycerate kinase
ART_2614	ENOG410667J	hydrolase
ART_2616	ENOG4105D7K	pfkb domain protein
ART_2622	ENOG4108ZGX	Histidine kinase
ART_2636	ENOG4105E2A	Dehydrogenase
ART_2640	ENOG4105CBG	Sulfatase
ART_2643	ENOG4105DRS	transport system, permease
ART_2644	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
ART_2646	ENOG4105CBG	Sulfatase
ART_2647	ENOG4108JQ1	Dehydrogenase
ART_2650	ENOG41080R8	Conserved Protein
ART_2651	ENOG4107QR9	Iron-sulfur cluster binding protein
ART_2652	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
ART_2655	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
ART_2656	ENOG4105C26	Dehydrogenase
ART_2657	ENOG4105C7K	acetolactate synthase
ART_2658	ENOG4105G9B	Transcriptional regulator
ART_2659	ENOG4105CSH	Transporter
ART_2660	ENOG4105KME	endoribonuclease L-psp
ART_2661	ENOG4105JSC	dimethylmenaquinone methyltransferase
ART_2665	ENOG4105EHG	Permease protein
ART_2666	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
ART_2675	ENOG4105CDW	Resistance protein
ART_2681	ENOG4105DAX	Pfam:DUF2983
ART_2685	ENOG4105KME	endoribonuclease L-psp
ART_2686	ENOG4108JQ6	ABC transporter
ART_2687	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
ART_2688	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
ART_2689	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
ART_2692	ENOG4105DU0	nucleoside hydrolase
ART_2693	ENOG4105ETE	Transcriptional regulator (LacI family
ART_2698	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
ART_2699	ENOG4105C87	Aminotransferase class I and II
ART_2708	ENOG4105DFM	M18 family aminopeptidase
ART_2710	ENOG4105WH1	Two component transcriptional regulator luxr family
ART_2711	ENOG4105BZU	Histidine kinase
ART_2715	ENOG4106UW1	Major Facilitator superfamily
ART_2720	ENOG4105C5H	ABC transporter
ART_2721	ENOG4108ZGX	Histidine kinase
ART_2722	ENOG4105WH1	Two component transcriptional regulator luxr family
ART_2723	ENOG4108IUX	(ABC) transporter
ART_2728	ENOG4105WH1	Two component transcriptional regulator luxr family
ART_2730	ENOG4105K4H	Nlp p60 protein
ART_2731	ENOG4108VB1	regulatoR
ART_2732	ENOG4105BZU	Histidine kinase
ART_2738	ENOG4107TB6	phosphoglycerate mutase
ART_2739	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
ART_2743	ENOG4105C3M	thioredoxin reductase
ART_2744	ENOG4105K63	Thioredoxin
ART_2752	ENOG410836F	Transposase
ART_2753	ENOG410836F	Transposase
ART_2758	ENOG4107QJE	Chromosome Partitioning Protein
ART_2759	ENOG4107XUG	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
ART_2761	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
ART_2763	ENOG41084CH	50S ribosomal protein l34
ART_2765	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
ART_2766	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
ART_2767	ENOG4108J5G	6-phosphogluconate dehydrogenase
ART_2768	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
ART_2769	ENOG4105K7N	UPF0232 protein
ART_2770	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
ART_2771	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
ART_2773	ENOG4108ZED	Transmembrane domain of unknown function (DUF3566)
ART_2779	ENOG4105MXW	flavin reductase domain protein, FMN-binding
ART_2782	ENOG4105RHY	Pfam:UPF0157
ART_2786	ENOG4105ZJT	Cell division protein CrgA
ART_2787	ENOG4108U4N	(sortase) family
ART_2791	ENOG4107TPY	serine threonine protein kinase
ART_2792	ENOG4105CJN	penicillin-binding protein
ART_2795	ENOG4105HZM	Fha domain containing protein
ART_2796	ENOG4105TV9	FHA Domain-Containing protein
ART_2808	ENOG410829C	Binds together with S18 to 16S ribosomal RNA (By similarity)
ART_2810	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
ART_2811	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
ART_2813	ENOG4105CDU	Replicative dna helicase
ART_2814	ENOG4107QI1	Mate efflux family protein
ART_2818	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
ART_2819	ENOG4108SU4	UPF0309 protein
ART_2822	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
ART_2827	ENOG4105VPX	protein, conserved in bacteria
ART_2834	ENOG4105CPQ	Dehydrogenase
ART_2838	ENOG4105DKT	Transcriptional regulator
ART_2840	ENOG4105DEI	Mannitol dehydrogenase
ART_2841	ENOG4105C7K	acetolactate synthase
ART_2845	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
ART_2850	ENOG4105NAU	thioesterase Superfamily protein
ART_2852	ENOG4107QTF	adenylosuccinate lyase
ART_2855	ENOG41082T9	Membrane
ART_2856	ENOG4105CIH	Imidazole acetol-phosphate transaminase
ART_2858	ENOG4105CPP	Dehydrogenase, E1 component
ART_2859	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
ART_2864	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
ART_2868	ENOG4105D9R	oxidoreductase
ART_2880	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
ART_2887	ENOG4107QN2	dihydrolipoyl dehydrogenase
ART_2889	ENOG4105E90	ABC transporter
ART_2890	ENOG4105E90	ABC transporter
ART_2891	ENOG4108IJ8	ABC transporter
ART_2892	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
ART_2894	ENOG4105E6M	Sulphatase-modifying factor protein
ART_2909	ENOG4107TXC	Transcriptional regulator
ART_2911	ENOG4108URH	decarboxylase
ART_2915	ENOG4105CHF	Glutathione S-transferase
ART_2921	ENOG4105DQ5	transport system permease protein
ART_2922	ENOG4105TVJ	transport system, permease
ART_2923	ENOG4105E0A	ABC, transporter
ART_2925	ENOG4108SQ4	Glyoxalase Bleomycin resistance protein (Dioxygenase
ART_2927	ENOG4105BZ1	(ABC) transporter
ART_2931	ENOG4105KDC	50s ribosomal protein l28
ART_2932	ENOG4105W0E	50S ribosomal protein L33
ART_2933	ENOG41080FR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
ART_2934	ENOG4108426	dNA-binding protein
ART_2935	ENOG4108T5E	Copper resistance protein
ART_2938	ENOG4105D7A	ATP-binding protein
ART_2940	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
ART_2942	ENOG4105E8G	Major facilitator Superfamily
ART_2949	ENOG4107RWR	Sodium hydrogen exchanger
ART_2951	ENOG4105DHP	deoxycytidine triphosphate deaminase
ART_2953	ENOG4105D65	subunit l
ART_2954	ENOG4105MKQ	Monovalent cation H antiporter subunit C
ART_2955	ENOG4108JPZ	Monovalent cation H antiporter subunit D
ART_2956	ENOG4105SC1	monovalent cation H antiporter subunit E
ART_2957	ENOG41080TA	Multiple resistance and ph regulation protein f
ART_2958	ENOG4105KJM	monovalent cation h antiporter subunit g
ART_2960	ENOG4105NSK	ABC superfamily ATP binding cassette transporter membrane protein
ART_2961	ENOG4108JJB	ABC transporter
ART_2963	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
ART_2964	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
ART_2970	ENOG4108ZJ4	polysaccharide deacetylase
ART_2971	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
ART_2972	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
ART_2974	ENOG4105FF5	Membrane
ART_2976	ENOG4108SEA	Esterase
ART_2981	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
ART_2983	ENOG4105KJF	protein tyrosine phosphatase
ART_2985	ENOG4105E3B	Multicopper oxidase
ART_2987	ENOG4108M6P	methyltransferase
ART_2988	ENOG4105CFG	Acts as a chaperone (By similarity)
ART_2989	ENOG4108093	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ART_2990	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
ART_2991	ENOG4105KNI	merR family transcriptional Regulator
ART_2992	ENOG4105C0D	helicase
ART_2996	ENOG4108IUE	nitrate reductase beta subunit
ART_2999	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
ART_3000	ENOG4105C1J	atp-dependent rna helicase
ART_3002	ENOG4105ENE	Histidine kinase
ART_3003	ENOG4105WH1	Two component transcriptional regulator luxr family
ART_3005	ENOG4105JAB	phenazine biosynthesis protein, phzf family
ART_3006	ENOG41090B9	response to stress
ART_3012	ENOG4108S01	response regulator
ART_3013	ENOG4105BZU	Histidine kinase
ART_3023	ENOG4105VZ8	Transcriptional regulator
ART_3027	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
ART_3030	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
ART_3036	ENOG4105C12	Phosphoribosylglycinamide synthetase
ART_3037	ENOG4105C8V	SAICAR synthetase
ART_3040	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
ART_3042	ENOG4107RGJ	metallophosphoesterase
ART_3043	ENOG4105BZ4	penicillin-binding protein
ART_3048	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
ART_3051	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
ART_3054	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
ART_3055	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
ART_3060	ENOG4105CI2	imidazolone-5-propionate hydrolase
ART_3069	ENOG4108I5C	dEAD DEAH box helicase
ART_3071	ENOG4105C72	UPF0176 protein
ART_3072	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
ART_3073	ENOG4105KT7	mgtC SapB transporter
ART_3074	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
ART_3075	ENOG4107R33	ppx gppa phosphatase
ART_3076	ENOG4105EY0	Xylose isomerase domain protein TIM barrel
ART_3077	ENOG4105II7	pyrroline-5-carboxylate reductase
ART_3078	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
ART_3081	ENOG4107ZYR	domain protein
ART_3082	ENOG4105CZN	Potassium uptake protein
ART_3083	ENOG4105DGU	Histone deacetylase
ART_3085	ENOG4105D82	Glutamate dehydrogenase
ART_3086	ENOG4105E53	ec 3.2.1.28
ART_3088	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
ART_3096	ENOG4105ETE	Transcriptional regulator (LacI family
ART_3098	ENOG4105ETE	Transcriptional regulator (LacI family
ART_3102	ENOG4105DET	Rhamnulokinase
ART_3104	ENOG4105I82	acetyl xylan esterase
ART_3105	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
ART_3107	ENOG4108RXW	HAD-superfamily subfamily IB hydrolase
ART_3109	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
ART_3112	ENOG4108YYC	ycei family
ART_3113	ENOG4108RH7	phosphoglycerate mutase
ART_3114	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ART_3115	ENOG4107QIV	Cytochrome c biogenesis protein
ART_3117	ENOG4105CRE	cytochrome C
ART_3121	ENOG4105C5H	ABC transporter
ART_3128	ENOG4105BZ1	(ABC) transporter
ART_3130	ENOG4108M8W	Monooxygenase
ART_3132	ENOG4105C08	Histidine kinase
ART_3133	ENOG4108KXV	response regulator
ART_3135	ENOG4107RCV	ABC transporter, permease
ART_3136	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
ART_3137	ENOG4105CN5	Metallo-Beta-Lactamase
ART_3142	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
ART_3143	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
ART_3146	ENOG41060NJ	transcriptional regulator
ART_3149	ENOG4105HS6	binding-protein-dependent transport systems inner membrane Component
ART_3150	ENOG4105DRS	transport system, permease
ART_3151	ENOG4105CK5	oxidoreductase
ART_3153	ENOG4108MR6	WD40-like Beta Propeller Repeat
ART_3155	ENOG4105C0H	protease
ART_3157	ENOG4107R9S	Malate synthase
ART_3164	ENOG4105CHR	reductase
ART_3167	ENOG4105QPS	Monooxygenase
ART_3169	ENOG4105F1N	DNA alkylation repair
ART_3170	ENOG41082F9	transcriptional regulator
ART_3183	ENOG4105GRZ	Ycii-related protein
ART_3190	ENOG4105CNV	Aldolase
ART_3193	ENOG4105C26	Dehydrogenase
ART_3196	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
ART_3200	ENOG4105CIS	alcohol dehydrogenase
ART_3205	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
ART_3224	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
ART_3238	ENOG4105I6B	RNA polymerase
ART_3241	ENOG4108S0J	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates (By similarity)
ART_3243	ENOG4107QRT	dEAD DEAH box helicase
ART_3248	ENOG4105BZU	Histidine kinase
ART_3249	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ART_3254	ENOG4108Z6B	deaminase
ART_3255	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
ART_3258	ENOG4105RV9	Transcriptional regulator
ART_3261	ENOG4105M4E	phosphohistidine phosphatase, SixA
ART_3263	ENOG410836F	Transposase
ART_3264	ENOG4105CJW	magnesium transporter
ART_3265	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
ART_3266	ENOG4105DKQ	ROK family
ART_3268	ENOG4108JQ7	(ABC) transporter
ART_3270	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
ART_3271	ENOG4105DEF	Extracellular solute-binding protein, family 5
ART_3272	ENOG41073TP	transcriptional regulator
ART_3275	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
ART_3277	ENOG41081JD	Transcriptional regulator
ART_3279	ENOG4107QKV	phosphomannomutase
ART_3280	ENOG4105C9U	ATP-dependent DNA helicase RecQ
ART_3284	ENOG4105DIA	mandelate racemase muconate lactonizing
ART_3296	ENOG4107T31	5'-nucleotidase
ART_3300	ENOG4105D22	carbon starvation protein
ART_3302	ENOG4108VC7	Protein of unknown function (DUF2587)
ART_3306	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
ART_3309	ENOG4105C6E	dna polymerase iii
ART_3310	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
ART_3314	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
ART_3315	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
ART_3316	ENOG4105BZU	Histidine kinase
ART_3317	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ART_3320	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
ART_3321	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
ART_3322	ENOG4105C8N	cysteinyl-tRNA synthetase
ART_3323	ENOG4105C2N	RNA methyltransferase TrmH family group 3
ART_3328	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
ART_3330	ENOG41070F3	Catalyzes the ATP-dependent phosphorylation of maltose to maltose 1-phosphate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, GlgE and GlgB (By similarity)
ART_3331	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
ART_3337	ENOG4105EG2	ABC transporter, permease
ART_3338	ENOG4107R28	alpha amylase, catalytic region
ART_3339	ENOG4105CQB	FAD linked oxidase domain protein
ART_3341	ENOG4108IJ9	(ABC) transporter
ART_3342	ENOG4105DZC	cytosine deaminase
ART_3343	ENOG4108K4C	ec 3.1.3.12
ART_3344	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
ART_3360	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
ART_3362	ENOG4105ETE	Transcriptional regulator (LacI family
ART_3367	ENOG4105DRS	transport system, permease
ART_3368	ENOG4108IJ9	(ABC) transporter
ART_3376	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
ART_3394	ENOG4108R85	Short chain dehydrogenase
ART_3395	ENOG4105DEI	Mannitol dehydrogenase
ART_3397	ENOG4105CNN	ABC, transporter
ART_3398	ENOG4105C2J	ABC transporter
ART_3399	ENOG4107Z1W	Fructose transport system kinase
ART_3400	ENOG4105ETE	Transcriptional regulator (LacI family
ART_3401	ENOG4107QKS	N-acylglucosamine 2-epimerase
ART_3434	ENOG4105CPQ	Dehydrogenase
ART_3435	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
ART_3439	ENOG4108ZBR	Gcn5-related n-acetyltransferase
ART_3441	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
ART_3442	ENOG4105CH7	arginosuccinase
ART_3443	ENOG4108I5D	sulfate abc transporter
ART_3444	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
ART_3449	ENOG4105CY2	Citrate transporter
ART_3456	ENOG4105C10	Electron transfer flavoprotein
ART_3459	ENOG4105CHR	reductase
ART_3461	ENOG4105CSH	Transporter
ART_3462	ENOG4105CHR	reductase
ART_3467	ENOG4105ERH	Fumarylacetoacetate hydrolase
ART_3468	ENOG4108Z6Z	Transcriptional regulator
ART_3471	ENOG410667J	hydrolase
ART_3476	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
ART_3477	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
ART_3480	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
ART_3481	ENOG4108JJB	ABC transporter
ART_3482	ENOG4107ZYJ	bioY protein
ART_3483	ENOG4105C1G	acyl-Coa dehydrogenase
ART_3485	ENOG4107QX3	carboxylase
ART_3490	ENOG4105C5X	domain protein
ART_3491	ENOG4105CHR	reductase
ART_3492	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
ART_3493	ENOG4108RZE	Tetr family transcriptional regulator
ART_3494	ENOG4105CSH	Transporter
ART_3495	ENOG4105CEY	Amp-dependent synthetase and ligase
ART_3498	ENOG4108JIK	carboxylase
ART_3499	ENOG4105CI0	Citrate lyase
ART_3501	ENOG4108IV0	ABC, transporter
ART_3502	ENOG4105C0Z	ABC transporter
ART_3505	ENOG4108IG5	Transcriptional regulator
ART_3509	ENOG41087EV	Hsp20/alpha crystallin family
ART_3511	ENOG4105SCY	DNAK suppressor
ART_3512	ENOG4105WH1	Two component transcriptional regulator luxr family
ART_3514	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
ART_3517	ENOG4105EKQ	RNA-directed DNA polymerase
ART_3526	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
ART_3530	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
ART_3533	ENOG4105C7W	Xanthine dehydrogenase
ART_3534	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
ART_3535	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
ART_3538	ENOG4106PVI	ATP-dependent carboxylate-amine ligase (By similarity)
ART_3548	ENOG4105DQE	DNA ligase
ART_3549	ENOG4105FDF	Could be involved in DNA repair (By similarity)
ART_3552	ENOG4108Z0Z	intracellular protease Pfpi family
ART_3557	ENOG4105EKQ	RNA-directed DNA polymerase
ART_3560	ENOG4105DQ5	transport system permease protein
ART_3561	ENOG4105TVJ	transport system, permease
ART_3562	ENOG4105E0A	ABC, transporter
ART_3571	ENOG4105CSH	Transporter
ART_3572	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
ART_3576	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ART_3577	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ART_3580	ENOG4105CSH	Transporter
ART_3581	ENOG4105C7K	acetolactate synthase
ART_3583	ENOG4105WH1	Two component transcriptional regulator luxr family
ART_3584	ENOG4105BZU	Histidine kinase
ART_3585	ENOG4105EYF	MMPL domain protein
ART_3589	ENOG4105CBG	Sulfatase
ART_3590	ENOG4105CBG	Sulfatase
ART_3595	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
ART_3601	ENOG4105D7N	magnesium and cobalt transport protein CorA
ART_3605	ENOG4105CC5	ABC transporter
ART_3606	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
ART_3618	ENOG4108JQ6	ABC transporter
ART_3619	ENOG4105E2D	ec 3.2.1.52
ART_3623	ENOG4106N3A	copper homeostasis protein cutc
ART_3625	ENOG4105CGD	Nad-dependent epimerase dehydratase
ART_3630	ENOG4105EWK	phytoene
ART_3634	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
ART_3640	ENOG4105CPU	Monooxygenase
ART_3643	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
ART_3644	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
ART_3645	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
ART_3646	ENOG4108YYH	Nadph-dependent fmn reductase
ART_3655	ENOG410667J	hydrolase
ART_3667	ENOG4105WH1	Two component transcriptional regulator luxr family
ART_3671	ENOG4105WH1	Two component transcriptional regulator luxr family
ART_3676	ENOG4105C26	Dehydrogenase
ART_3684	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
ART_3689	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
ART_3693	ENOG4105BZU	Histidine kinase
ART_3694	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ART_3695	ENOG4106KS4	Sulfatase
ART_3696	ENOG4105CBG	Sulfatase
ART_3700	ENOG4105CMD	Transcriptional regulator, GntR family
ART_3701	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
ART_3702	ENOG4106AM8	polysaccharide lyase family 8
ART_3705	ENOG4105CBG	Sulfatase
ART_3707	ENOG41061MV	Arylsulfatase
ART_3715	ENOG4107R8H	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
ART_3717	ENOG4105DR5	peptidase
ART_3727	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
ART_3729	ENOG4105CDA	abc transporter atp-binding protein
ART_3730	ENOG4105DRP	amino acid AbC transporter
ART_3732	ENOG4105BZ1	(ABC) transporter
ART_3733	ENOG4105KBX	Transcriptional regulator, TetR family
ART_3734	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
ART_3735	ENOG4105CI2	imidazolone-5-propionate hydrolase
ART_3736	ENOG4105CH2	amidohydrolase
ART_3743	ENOG4105DTR	rard protein
ART_3744	ENOG4108MWI	inositol mono-phosphatase
ART_3748	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
ART_3753	ENOG4105F27	Major Facilitator
ART_3754	ENOG4105CV8	reductase
ART_3755	ENOG41082J7	Rhodanese domain protein
ART_3763	ENOG4108JCI	Transcriptional regulator
ART_3769	ENOG4105C7K	acetolactate synthase
ART_3770	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
ART_3783	ENOG4105ECP	epimerase
ART_3787	ENOG4107YCY	Transcriptional regulator
ART_3789	ENOG4108IJ0	Aspartate ammonia-lyase
ART_3793	ENOG4105JXH	GntR family transcriptional regulator
ART_3795	ENOG4105CMT	Dihydroxyacetone kinase
ART_3796	ENOG4107YVI	ribose 5-phosphate isomerase
ART_3797	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
ART_3799	ENOG4105CSP	Major Facilitator Superfamily
ART_3800	ENOG4105CP7	Triose-phosphate isomerase
ART_3802	ENOG4105C6Z	Gluconate
ART_3803	ENOG4105ZXK	Dehydrogenase
ART_3805	ENOG4107EJG	GntR family transcriptional regulator
ART_3809	ENOG4108ZEY	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
ART_3817	ENOG4105DEF	Extracellular solute-binding protein, family 5
ART_3821	ENOG4105C93	Xylose Isomerase
ART_3823	ENOG4107WI4	Aldose-1-epimerase
ART_3824	ENOG4105CHH	sulfate transporter
ART_3837	ENOG4108JU3	Alkyl hydroperoxide reductase
ART_3843	ENOG4105CSU	acyl-Coa dehydrogenase
ART_3846	ENOG4105VG9	Plasmid stabilization system
ART_3847	ENOG41067D0	Antitoxin component of a toxin-antitoxin (TA) module. Upon expression in M.smegmatis neutralizes the effect of toxin RelE2
ART_3850	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
ART_3852	ENOG4105VEQ	Cold shock protein
ART_3857	ENOG41079KZ	Major Facilitator Superfamily
ART_3860	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ART_3861	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
ART_3862	ENOG4105DC1	bifunctional purine biosynthesis protein purh
ART_3864	ENOG4105F9F	transposase
ART_3866	ENOG4105E9K	Isocitrate dehydrogenase
ART_3868	ENOG4105C32	Amino acid ABC transporter (Permease)
ART_3869	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
ART_3871	ENOG4105C0Z	ABC transporter
ART_3872	ENOG4108IV0	ABC, transporter
ART_3875	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
ART_3876	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
ART_3877	ENOG4108JP0	extracellular solute-binding protein family 1
ART_3878	ENOG4105E2R	ROK family
ART_3880	ENOG4107SET	aldo keto reductase
ART_3882	ENOG4107ZR7	Membrane
ART_3884	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
ART_3885	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
ART_3887	ENOG4105D4Y	metalloprotease
ART_3888	ENOG4105WH1	Two component transcriptional regulator luxr family
ART_3889	ENOG4105BZU	Histidine kinase
ART_3893	ENOG4105C31	Tryptophanyl-tRNA synthetase
ART_3896	ENOG4108ZXC	Two component transcriptional regulator, luxr family
ART_3897	ENOG4105E33	succinate dehydrogenase
ART_3902	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
ART_3903	ENOG4107RM1	amidohydrolase
ART_3904	ENOG4105DIH	basic membrane
ART_3905	ENOG4108JQ9	ABC transporter
ART_3906	ENOG4105UIB	(ABC) transporter
ART_3911	ENOG4107XFB	conserved TRANSMEMBRANE PROTEIN
ART_3912	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
ART_3916	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
ART_3925	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
ART_3927	ENOG4105E98	transcriptional regulator DeoR family
ART_3928	ENOG4107WI4	Aldose-1-epimerase
ART_3930	ENOG4105C7B	Threonine dehydratase
ART_3931	ENOG4107YD5	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
ART_3933	ENOG4105T1M	mycothiol conjugate amidase mca
ART_3935	ENOG4105C7Z	Conserved Protein
ART_3937	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
ART_3940	ENOG4108UT2	hemolysin iii
ART_3941	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
ART_3943	ENOG4108IAB	Phoh family
ART_3946	ENOG4106YYS	transcriptional regulatory protein
ART_3947	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
ART_3948	ENOG4105D4T	Citrate transporter
ART_3953	ENOG4105C9Q	fumarate hydratase class II
ART_3954	ENOG4108V9Q	carbonic anhydrase
ART_3958	ENOG4105EIP	mannose-6-phosphate isomerase
ART_3964	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
ART_3965	ENOG4107RGC	Glycosyl transferase, family 2
ART_3970	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
ART_3971	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
ART_3981	ENOG4107QYR	Signal peptidase i
ART_3988	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
ART_3989	ENOG4105F8V	Hydrolase, tatD family
ART_3991	ENOG4106839	domain protein
ART_3992	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
ART_3994	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
ART_3995	ENOG4105C5H	ABC transporter
ART_4000	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
ART_4002	ENOG4107XT7	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
ART_4003	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
ART_4008	ENOG4105D3Q	Sugar transferase
ART_4009	ENOG4107TYG	Oxidoreductase domain-containing protein
ART_4010	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
ART_4011	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
ART_4014	ENOG4105PSV	Polysaccharide Biosynthesis Protein
ART_4016	ENOG4107EF8	Glycosyl transferase (Group 1
ART_4021	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
ART_4022	ENOG4105D5U	fad dependent oxidoreductase
ART_4024	ENOG4108UNV	SUF system FeS assembly protein, NifU family
ART_4039	ENOG4108TJN	glycosyl transferase group 1
ART_4041	ENOG4105D3Q	Sugar transferase
ART_4043	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
ART_4057	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
ART_4060	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
ART_4063	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
ART_4067	ENOG4105C8J	)-transporter
ART_4070	ENOG4105CSH	Transporter
ART_4071	ENOG4108JIK	carboxylase
ART_4074	ENOG4107WR6	Maf-like protein
ART_4080	ENOG4105C26	Dehydrogenase
ART_4084	ENOG4107RR1	TRANSCRIPTIONal
ART_4085	ENOG4105EYF	MMPL domain protein
ART_4090	ENOG4105D8K	carboxyl transferase
ART_4097	ENOG4105WH1	Two component transcriptional regulator luxr family
ART_4100	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
ART_4105	ENOG4108ZF3	Phosphatase
ART_4109	ENOG4105EC2	ftsk spoIIIe
ART_4111	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
ART_4112	ENOG4105ECY	inositol monophosphatase
ART_4116	ENOG4105BZU	Histidine kinase
ART_4117	ENOG4108S01	response regulator
ART_4120	ENOG4105CG3	alpha amylase, catalytic region
ART_4121	ENOG4105I1K	ABC transporter
ART_4124	ENOG4105E2R	ROK family
ART_4125	ENOG4108MXC	l-carnitine dehydratase bile acid-inducible protein F
ART_4130	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
ART_4131	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
ART_4132	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
ART_4136	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
ART_4139	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
ART_4141	ENOG4108JQ1	Dehydrogenase
ART_4144	ENOG4105CTZ	aminopeptidase c
ART_4145	ENOG4108MTT	Glutamate-rich protein grpB
ART_4146	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
ART_4147	ENOG4108RJ7	Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP) (By similarity)
ART_4150	ENOG4105CJ1	ABC, transporter
ART_4152	ENOG4105E2D	ec 3.2.1.52
ART_4154	ENOG4105CPQ	Dehydrogenase
ART_4155	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
ART_4158	ENOG4105E6M	Sulphatase-modifying factor protein
ART_4159	ENOG4105FC8	fad dependent oxidoreductase
ART_4160	ENOG4108NIW	Leucine export protein LeuE
ART_4161	ENOG4105CI2	imidazolone-5-propionate hydrolase
ART_4167	ENOG4105E98	transcriptional regulator DeoR family
ART_4168	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
ART_4171	ENOG4105BZM	domain protein
ART_4172	ENOG4108IQK	o-acetylhomoserine
ART_4173	ENOG4105DWV	Homoserine O-trans-acetylase
ART_4176	ENOG41090WU	lipolytic protein G-D-S-L family
ART_4184	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
ART_4192	ENOG41065KQ	synthase
ART_4193	ENOG4105CJW	magnesium transporter
ART_4194	ENOG4108XG4	DNA-binding transcriptional regulator
ART_4195	ENOG4105ECB	domain protein
ART_4199	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
ART_4200	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
ART_4201	ENOG4105C2C	drug resistance transporter, Bcr CflA
ART_4205	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
ART_4206	ENOG4105C1G	acyl-Coa dehydrogenase
ART_4208	ENOG4105CE9	30S ribosomal protein S2
ART_4209	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
ART_4210	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
ART_4211	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
ART_4217	ENOG4108NEV	two component transcriptional regulator, LytTR family
ART_4218	ENOG4108HRK	Histidine kinase
ART_4220	ENOG4107QN1	sodium solute
ART_4223	ENOG4105CPP	Dehydrogenase, E1 component
ART_4224	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
ART_4227	ENOG41067SE	Tetr family transcriptional regulator
ART_4228	ENOG4107QX3	carboxylase
ART_4230	ENOG4105C1G	acyl-Coa dehydrogenase
ART_4239	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
ART_4240	ENOG4105DZP	Membrane-associated zinc metalloprotease
ART_4244	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
ART_4246	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
ART_4249	ENOG4105CIG	ABC transporter
ART_4250	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
ART_4256	ENOG4107Z1I	Required for maturation of 30S ribosomal subunits (By similarity)
ART_4259	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
ART_4261	ENOG4107ZPY	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
ART_4262	ENOG4105C1G	acyl-Coa dehydrogenase
ART_4264	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
ART_4271	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
ART_4272	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
ART_4273	ENOG4105C1V	Peptidase, M16
ART_4281	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
ART_4283	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
ART_4286	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
ART_4287	ENOG4105CN5	Metallo-Beta-Lactamase
ART_4288	ENOG4107QZI	cell division protein FtsK
ART_4290	ENOG4105CEV	competence damage-inducible protein
ART_4291	ENOG4105WBV	Transcriptional regulator
ART_4292	ENOG4105XMC	MarR family Transcriptional regulator
ART_4294	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
ART_4295	ENOG4105KC9	Modulates RecA activity (By similarity)
ART_4297	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
ART_4298	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
ART_4299	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
ART_4300	ENOG4107Y49	methyltransferase
ART_4301	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
ART_4304	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
ART_4306	ENOG4105CIH	Imidazole acetol-phosphate transaminase
ART_4307	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
ART_4308	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
ART_4310	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
ART_4314	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
ART_4315	ENOG41084BS	50S ribosomal protein L35
ART_4316	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
ART_4320	ENOG4105F27	Major Facilitator
ART_4324	ENOG4105CEY	Amp-dependent synthetase and ligase
ART_4330	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
ART_4331	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
ART_4335	ENOG41073TP	transcriptional regulator
ART_4337	ENOG4108EF6	Proline imino-peptidase
ART_4343	ENOG4107U9T	Pfam:Ribonuclease_BN
ART_4344	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
ART_4345	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
ART_4346	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
ART_4347	ENOG4105CAS	nag kinase
ART_4348	ENOG4105C8Y	Acetylornithine aminotransferase
ART_4349	ENOG4105DBV	ornithine carbamoyltransferase
ART_4350	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
ART_4352	ENOG4105CDH	Citrulline--aspartate ligase
ART_4353	ENOG4105CH7	arginosuccinase
ART_4359	ENOG4105CPQ	Dehydrogenase
ART_4361	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
ART_4363	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)