locus-tag	class	description
ASPU41_00030	COG1126	abc transporter atp-binding protein
ASPU41_00035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASPU41_00040	COG0765	amino acid transport
ASPU41_00045	COG0765	amino acid transport
ASPU41_00050	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ASPU41_00055	COG2171	N-acyltransferase activity
ASPU41_00070	COG3226	Transcriptional regulator
ASPU41_00120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASPU41_00135	COG4172	Belongs to the ABC transporter superfamily
ASPU41_00155	COG4166	transmembrane transport
ASPU41_00160	COG0012	GTP binding
ASPU41_00165	COG1322	Protein conserved in bacteria
ASPU41_00170	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ASPU41_00180	COG1570	exodeoxyribonuclease VII activity
ASPU41_00185	COG1722	exodeoxyribonuclease VII activity
ASPU41_00190	COG2326	polyphosphate kinase activity
ASPU41_00205	COG1174	glycine betaine transport
ASPU41_00210	COG1174	glycine betaine transport
ASPU41_00220	COG1162	GTPase activity
ASPU41_00230	COG2971	BadF BadG BcrA BcrD
ASPU41_00240	COG0583	DNA-binding transcription factor activity
ASPU41_00245	COG2814	Major facilitator Superfamily
ASPU41_00250	COG0626	cystathionine gamma-synthase activity
ASPU41_00270	COG0598	Magnesium transport protein CorA
ASPU41_00275	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ASPU41_00285	COG0488	(ABC) transporter
ASPU41_00290	COG2890	protein-(glutamine-N5) methyltransferase activity
ASPU41_00305	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ASPU41_00310	COG1695	Transcriptional regulator
ASPU41_00335	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ASPU41_00340	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ASPU41_00360	COG0519	Catalyzes the synthesis of GMP from XMP
ASPU41_00360	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ASPU41_00380	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ASPU41_00385	COG0516	GMP reductase activity
ASPU41_00425	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ASPU41_00425	COG2755	lipolytic protein G-D-S-L family
ASPU41_00440	COG0459	protein refolding
ASPU41_00445	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ASPU41_00460	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ASPU41_00465	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ASPU41_00470	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ASPU41_00485	COG0802	atpase or kinase
ASPU41_00490	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ASPU41_00510	COG0438	transferase activity, transferring glycosyl groups
ASPU41_00515	COG2759	Belongs to the formate--tetrahydrofolate ligase family
ASPU41_00530	COG0667	Aldo Keto reductase
ASPU41_00555	COG0736	holo-[acyl-carrier-protein] synthase activity
ASPU41_00560	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ASPU41_00565	COG1072	(Pantothenic acid kinase))
ASPU41_00570	COG1876	peptidase activity
ASPU41_00575	COG1970	mechanosensitive ion channel activity
ASPU41_00590	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ASPU41_00595	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ASPU41_00600	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ASPU41_00625	COG0455	bacterial-type flagellum organization
ASPU41_00665	COG1192	Involved in chromosome partitioning
ASPU41_00700	COG0101	tRNA pseudouridine synthase activity
ASPU41_00705	COG0203	ribosomal protein L17
ASPU41_00710	COG0202	RNA polymerase activity
ASPU41_00715	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ASPU41_00720	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ASPU41_00725	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ASPU41_00730	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ASPU41_00735	COG3191	aminopeptidase activity
ASPU41_00740	COG1175	transmembrane transport
ASPU41_00750	COG1653	transport
ASPU41_00760	COG0563	adenylate kinase activity
ASPU41_00770	COG0200	Binds to the 23S rRNA
ASPU41_00775	COG1841	ribosomal large subunit assembly
ASPU41_00780	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ASPU41_00790	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ASPU41_00795	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ASPU41_00800	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ASPU41_00805	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ASPU41_00810	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ASPU41_00815	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ASPU41_00820	COG0255	Belongs to the universal ribosomal protein uL29 family
ASPU41_00825	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ASPU41_00830	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ASPU41_00835	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ASPU41_00840	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ASPU41_00845	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ASPU41_00850	COG0089	rRNA binding
ASPU41_00855	COG0088	Forms part of the polypeptide exit tunnel
ASPU41_00860	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ASPU41_00865	COG0051	transcription antitermination factor activity, RNA binding
ASPU41_00880	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ASPU41_00885	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ASPU41_00890	COG0049	tRNA binding
ASPU41_00895	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ASPU41_00900	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ASPU41_00905	COG0085	RNA polymerase activity
ASPU41_00910	COG0183	Belongs to the thiolase family
ASPU41_00915	COG0442	prolyl-tRNA aminoacylation
ASPU41_00920	COG0222	ribosome binding
ASPU41_00925	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ASPU41_00935	COG0081	regulation of translation
ASPU41_00940	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ASPU41_00950	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ASPU41_00960	COG0436	Aminotransferase
ASPU41_00965	COG2197	response regulator
ASPU41_01020	COG3485	protocatechuate 3,4-dioxygenase
ASPU41_01030	COG0745	RESPONSE REGULATOR receiver
ASPU41_01035	COG0456	acetyltransferase
ASPU41_01040	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ASPU41_01050	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ASPU41_01055	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ASPU41_01090	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ASPU41_01105	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ASPU41_01110	COG0738	Major facilitator superfamily
ASPU41_01120	COG2030	dehydratase
ASPU41_01130	COG0659	secondary active sulfate transmembrane transporter activity
ASPU41_01150	COG4989	oxidoreductase activity
ASPU41_01155	COG0366	Alpha amylase catalytic
ASPU41_01160	COG1940	carbohydrate kinase activity
ASPU41_01165	COG0702	epimerase
ASPU41_01195	COG1051	belongs to the nudix hydrolase family
ASPU41_01230	COG0318	PFAM AMP-dependent synthetase and ligase
ASPU41_01240	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ASPU41_01265	COG0346	lactoylglutathione lyase activity
ASPU41_01330	COG1215	transferase activity, transferring glycosyl groups
ASPU41_01335	COG1366	Belongs to the anti-sigma-factor antagonist family
ASPU41_01345	COG0745	RESPONSE REGULATOR receiver
ASPU41_01350	COG5001	Diguanylate cyclase
ASPU41_01350	COG3300	MHYT domain
ASPU41_01365	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ASPU41_01370	COG3300	MHYT domain
ASPU41_01370	COG5001	Diguanylate cyclase
ASPU41_01380	COG0542	response to heat
ASPU41_01395	COG4974	Belongs to the 'phage' integrase family
ASPU41_01410	COG1666	GTP binding
ASPU41_01415	COG0501	Belongs to the peptidase M48B family
ASPU41_01435	COG1116	anion transmembrane transporter activity
ASPU41_01440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ASPU41_01450	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ASPU41_01455	COG0531	amino acid
ASPU41_01535	COG2186	Transcriptional regulator
ASPU41_01560	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ASPU41_01560	COG1648	precorrin-2 dehydrogenase activity
ASPU41_01575	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ASPU41_01585	COG1690	Belongs to the RtcB family
ASPU41_01610	COG0175	sulfate reduction
ASPU41_01625	COG2860	membrane
ASPU41_01645	COG0644	oxidoreductase
ASPU41_01650	COG2226	methyltransferase
ASPU41_01655	COG1169	isochorismate synthase
ASPU41_01660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASPU41_01665	COG0765	amino acid transport
ASPU41_01685	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ASPU41_01690	COG0018	arginyl-trna synthetase
ASPU41_01700	COG2132	Multicopper oxidase
ASPU41_01710	COG1846	Transcriptional regulator
ASPU41_01715	COG4948	Mandelate Racemase Muconate Lactonizing
ASPU41_01720	COG3764	Sortase (surface protein transpeptidase)
ASPU41_01730	COG1621	beta-fructofuranosidase activity
ASPU41_01775	COG0765	amino acid transport
ASPU41_01780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASPU41_01850	COG2801	Transposase and inactivated derivatives
ASPU41_01860	COG0508	dehydrogenase complex catalyzes the overall conversion of
ASPU41_01865	COG0022	dehydrogenase e1 component
ASPU41_01880	COG2244	polysaccharide biosynthetic process
ASPU41_01890	COG2826	transposase and inactivated derivatives, IS30 family
ASPU41_01900	COG2826	transposase and inactivated derivatives, IS30 family
ASPU41_01920	COG1484	DNA-dependent DNA replication
ASPU41_01945	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ASPU41_01965	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ASPU41_01970	COG1024	Enoyl-CoA hydratase
ASPU41_01975	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ASPU41_01980	COG2151	metal-sulfur cluster biosynthetic enzyme
ASPU41_01985	COG3396	Phenylacetate-CoA oxygenase
ASPU41_01990	COG3460	Phenylacetate-CoA oxygenase
ASPU41_01995	COG3396	Phenylacetate-CoA oxygenase
ASPU41_02000	COG0681	Belongs to the peptidase S26 family
ASPU41_02005	COG0489	protein tyrosine kinase activity
ASPU41_02020	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ASPU41_02025	COG1316	TRANSCRIPTIONal
ASPU41_02035	COG1088	dTDP-glucose 4,6-dehydratase activity
ASPU41_02040	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ASPU41_02050	COG1940	carbohydrate kinase activity
ASPU41_02055	COG0277	FAD linked oxidase domain protein
ASPU41_02060	COG2115	Belongs to the xylose isomerase family
ASPU41_02065	COG1070	Carbohydrate kinase
ASPU41_02070	COG0673	inositol 2-dehydrogenase activity
ASPU41_02075	COG0673	inositol 2-dehydrogenase activity
ASPU41_02100	COG0659	secondary active sulfate transmembrane transporter activity
ASPU41_02105	COG0789	Transcriptional regulator
ASPU41_02120	COG2217	Heavy metal translocating P-type atpase
ASPU41_02130	COG1611	Belongs to the LOG family
ASPU41_02135	COG1136	(ABC) transporter
ASPU41_02135	COG4591	ABC-type transport system involved in lipoprotein release permease component
ASPU41_02140	COG4591	ABC-type transport system involved in lipoprotein release permease component
ASPU41_02155	COG2217	Heavy metal translocating P-type atpase
ASPU41_02190	COG2132	Multicopper oxidase
ASPU41_02245	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ASPU41_02255	COG0857	belongs to the CobB CobQ family
ASPU41_02255	COG0280	phosphate acetyltransferase
ASPU41_02265	COG2050	protein possibly involved in aromatic compounds catabolism
ASPU41_02290	COG2030	dehydratase
ASPU41_02290	COG1012	belongs to the aldehyde dehydrogenase family
ASPU41_02295	COG2050	protein possibly involved in aromatic compounds catabolism
ASPU41_02305	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ASPU41_02305	COG1017	nitric oxide dioxygenase activity
ASPU41_02320	COG2755	lipolytic protein G-D-S-L family
ASPU41_02330	COG1250	3-hydroxyacyl-CoA dehydrogenase
ASPU41_02335	COG1024	Enoyl-CoA hydratase
ASPU41_02340	COG0183	Belongs to the thiolase family
ASPU41_02355	COG3237	CsbD-like
ASPU41_02370	COG0488	(ABC) transporter
ASPU41_02375	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ASPU41_02380	COG1121	(ABC) transporter
ASPU41_02390	COG1266	CAAX protease self-immunity
ASPU41_02400	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ASPU41_02430	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ASPU41_02440	COG0785	Cytochrome C biogenesis protein
ASPU41_02445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ASPU41_02450	COG0406	alpha-ribazole phosphatase activity
ASPU41_02455	COG2353	YceI-like domain
ASPU41_02470	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ASPU41_02480	COG0560	Phosphoserine phosphatase
ASPU41_02490	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ASPU41_02505	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ASPU41_02510	COG0640	Transcriptional regulator
ASPU41_02520	COG0123	including yeast histone deacetylase and acetoin utilization protein
ASPU41_02525	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ASPU41_02530	COG0569	domain protein
ASPU41_02535	COG0723	plastoquinol--plastocyanin reductase activity
ASPU41_02535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ASPU41_02555	COG3795	YCII-related domain
ASPU41_02560	COG0248	Ppx GppA phosphatase
ASPU41_02570	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ASPU41_02570	COG1754	DNA topoisomerase type I activity
ASPU41_02580	COG2890	protein-(glutamine-N5) methyltransferase activity
ASPU41_02585	COG0789	Transcriptional regulator
ASPU41_02615	COG1111	helicase
ASPU41_02615	COG1205	dead DEAH box helicase
ASPU41_02655	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ASPU41_02655	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ASPU41_02665	COG1051	belongs to the nudix hydrolase family
ASPU41_02670	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ASPU41_02680	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ASPU41_02730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ASPU41_02735	COG1408	metallophosphoesterase
ASPU41_02740	COG1132	(ABC) transporter
ASPU41_02745	COG1132	(ABC) transporter
ASPU41_02765	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ASPU41_02770	COG0151	Belongs to the GarS family
ASPU41_02790	COG1028	Short-chain dehydrogenase reductase Sdr
ASPU41_02805	COG0546	phosphoglycolate phosphatase activity
ASPU41_02815	COG3387	PFAM Glycoside hydrolase 15-related
ASPU41_02875	COG4948	Mandelate Racemase Muconate Lactonizing
ASPU41_02885	COG0800	Aldolase
ASPU41_02890	COG4948	Mandelate Racemase Muconate Lactonizing
ASPU41_02900	COG1175	transmembrane transport
ASPU41_02915	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ASPU41_02920	COG0589	response to stress
ASPU41_02965	COG2267	carboxylic ester hydrolase activity
ASPU41_02985	COG0693	protein deglycase activity
ASPU41_03090	COG2244	polysaccharide biosynthetic process
ASPU41_03100	COG0318	PFAM AMP-dependent synthetase and ligase
ASPU41_03125	COG0463	Glycosyl transferase, family 2
ASPU41_03145	COG1028	Short-chain dehydrogenase reductase Sdr
ASPU41_03150	COG1309	transcriptional regulator
ASPU41_03180	COG0395	ABC-type sugar transport system, permease component
ASPU41_03185	COG4209	transmembrane transport
ASPU41_03190	COG1609	Transcriptional regulator
ASPU41_03195	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ASPU41_03205	COG1349	DNA-binding transcription factor activity
ASPU41_03210	COG1070	Carbohydrate kinase
ASPU41_03225	COG2376	Dihydroxyacetone kinase
ASPU41_03240	COG1129	ABC transporter
ASPU41_03265	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ASPU41_03280	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ASPU41_03350	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ASPU41_03360	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ASPU41_03375	COG0596	Alpha beta hydrolase
ASPU41_03380	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ASPU41_03385	COG0579	oxidoreductase
ASPU41_03390	COG1960	acyl-CoA dehydrogenase activity
ASPU41_03395	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASPU41_03405	COG1028	Short-chain dehydrogenase reductase Sdr
ASPU41_03410	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ASPU41_03450	COG2807	transmembrane transport
ASPU41_03475	COG4867	von Willebrand factor, type A
ASPU41_03480	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
ASPU41_03500	COG3845	ABC transporter
ASPU41_03505	COG3415	Transposase
ASPU41_03505	COG2801	Transposase and inactivated derivatives
ASPU41_03510	COG1410	methionine synthase
ASPU41_03510	COG0646	methionine synthase
ASPU41_03540	COG1028	Short-chain dehydrogenase reductase Sdr
ASPU41_03545	COG1028	Short-chain dehydrogenase reductase Sdr
ASPU41_03560	COG0252	asparaginase activity
ASPU41_03565	COG1609	Transcriptional regulator
ASPU41_03570	COG2508	Transcriptional regulator
ASPU41_03585	COG0439	Biotin carboxylase
ASPU41_03590	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ASPU41_03595	COG1984	allophanate hydrolase subunit 2
ASPU41_03610	COG1984	allophanate hydrolase subunit 2
ASPU41_03615	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ASPU41_03620	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ASPU41_03675	COG4948	Mandelate Racemase Muconate Lactonizing
ASPU41_03695	COG2186	Transcriptional regulator
ASPU41_03705	COG1028	Short-chain dehydrogenase reductase Sdr
ASPU41_03710	COG0747	negative chemotaxis
ASPU41_03720	COG4608	Belongs to the ABC transporter superfamily
ASPU41_03725	COG0601	transmembrane transport
ASPU41_03740	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ASPU41_03755	COG0251	oxidation-reduction process
ASPU41_03760	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
ASPU41_03780	COG2801	Transposase and inactivated derivatives
ASPU41_03805	COG4974	Belongs to the 'phage' integrase family
ASPU41_03825	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ASPU41_03835	COG2267	carboxylic ester hydrolase activity
ASPU41_03875	COG0667	Aldo Keto reductase
ASPU41_03880	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ASPU41_03890	COG0590	tRNA wobble adenosine to inosine editing
ASPU41_03905	COG3257	ureidoglycine aminohydrolase activity
ASPU41_03910	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ASPU41_03915	COG3622	Belongs to the hyi family
ASPU41_03920	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ASPU41_03925	COG2226	methyltransferase
ASPU41_03940	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ASPU41_03955	COG0542	response to heat
ASPU41_03960	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ASPU41_03980	COG3585	molybdate ion transport
ASPU41_04015	COG2353	YceI-like domain
ASPU41_04020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ASPU41_04025	COG0135	phosphoribosylanthranilate isomerase activity
ASPU41_04040	COG2076	Multidrug Resistance protein
ASPU41_04060	COG0513	Belongs to the DEAD box helicase family
ASPU41_04100	COG2807	transmembrane transport
ASPU41_04105	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ASPU41_04115	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ASPU41_04145	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ASPU41_04150	COG0800	Aldolase
ASPU41_04170	COG1175	transmembrane transport
ASPU41_04180	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
ASPU41_04185	COG1414	Transcriptional regulator
ASPU41_04190	COG1921	L-seryl-tRNASec selenium transferase activity
ASPU41_04195	COG0251	oxidation-reduction process
ASPU41_04215	COG1802	Transcriptional regulator
ASPU41_04230	COG3971	2-oxopent-4-enoate hydratase activity
ASPU41_04245	COG0789	Transcriptional regulator
ASPU41_04250	COG0484	heat shock protein binding
ASPU41_04255	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ASPU41_04260	COG0443	Heat shock 70 kDa protein
ASPU41_04280	COG2409	Drug exporters of the RND superfamily
ASPU41_04315	COG1280	lysine exporter protein (LysE YggA)
ASPU41_04325	COG0477	Major facilitator Superfamily
ASPU41_04345	COG1028	Short-chain dehydrogenase reductase Sdr
ASPU41_04355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ASPU41_04360	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ASPU41_04365	COG0512	Glutamine amidotransferase of anthranilate synthase
ASPU41_04365	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ASPU41_04395	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ASPU41_04400	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ASPU41_04410	COG1122	ATPase activity
ASPU41_04415	COG4721	ABC-type cobalt transport system, permease component
ASPU41_04420	COG4702	Belongs to the UPF0303 family
ASPU41_04430	COG1320	monovalent cation:proton antiporter activity
ASPU41_04435	COG2212	antiporter activity
ASPU41_04455	COG2111	Na H antiporter
ASPU41_04455	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ASPU41_04470	COG0475	glutathione-regulated potassium exporter activity
ASPU41_04475	COG0717	Belongs to the dCTP deaminase family
ASPU41_04500	COG0583	DNA-binding transcription factor activity
ASPU41_04510	COG1012	belongs to the aldehyde dehydrogenase family
ASPU41_04515	COG0531	amino acid
ASPU41_04525	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ASPU41_04545	COG3387	PFAM Glycoside hydrolase 15-related
ASPU41_04550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ASPU41_04570	COG0433	COG0433 Predicted ATPase
ASPU41_04590	COG3336	cytochrome c oxidase
ASPU41_04595	COG0776	regulation of translation
ASPU41_04635	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ASPU41_04640	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ASPU41_04645	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ASPU41_04650	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ASPU41_04650	COG1017	nitric oxide dioxygenase activity
ASPU41_04670	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
ASPU41_04670	COG2066	Belongs to the glutaminase family
ASPU41_04695	COG1120	ATPase activity
ASPU41_04700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASPU41_04705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASPU41_04745	COG3012	SEC-C Motif Domain Protein
ASPU41_04755	COG0667	Aldo Keto reductase
ASPU41_04760	COG0702	epimerase
ASPU41_04770	COG0698	ribose 5-phosphate isomerase
ASPU41_04780	COG1028	Short-chain dehydrogenase reductase Sdr
ASPU41_04795	COG3959	Transketolase, thiamine diphosphate binding domain
ASPU41_04800	COG3958	Transketolase
ASPU41_04820	COG1595	DNA-templated transcription, initiation
ASPU41_04855	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ASPU41_04880	COG0039	L-malate dehydrogenase activity
ASPU41_04890	COG0640	Transcriptional regulator
ASPU41_04920	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ASPU41_04930	COG1522	sequence-specific DNA binding
ASPU41_04935	COG1280	lysine exporter protein (LysE YggA)
ASPU41_04960	COG1309	transcriptional regulator
ASPU41_04975	COG0477	Major facilitator Superfamily
ASPU41_04985	COG0246	Mannitol dehydrogenase
ASPU41_04990	COG2213	PTS system mannitol-specific
ASPU41_04990	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASPU41_05000	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ASPU41_05020	COG0686	Belongs to the AlaDH PNT family
ASPU41_05025	COG0673	inositol 2-dehydrogenase activity
ASPU41_05030	COG1309	transcriptional regulator
ASPU41_05035	COG0431	NADPH-dependent FMN reductase
ASPU41_05040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ASPU41_05045	COG0589	response to stress
ASPU41_05075	COG0318	PFAM AMP-dependent synthetase and ligase
ASPU41_05090	COG3485	protocatechuate 3,4-dioxygenase
ASPU41_05105	COG0583	DNA-binding transcription factor activity
ASPU41_05110	COG0508	dehydrogenase complex catalyzes the overall conversion of
ASPU41_05115	COG0022	dehydrogenase e1 component
ASPU41_05125	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ASPU41_05130	COG1950	PFAM Membrane protein of
ASPU41_05145	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ASPU41_05160	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASPU41_05165	COG1607	acyl-coa hydrolase
ASPU41_05170	COG1840	ABC-type Fe3 transport system, periplasmic component
ASPU41_05175	COG3842	ATPase activity
ASPU41_05180	COG1178	ABC-type Fe3 transport system permease component
ASPU41_05190	COG1414	Transcriptional regulator
ASPU41_05195	COG1970	mechanosensitive ion channel activity
ASPU41_05225	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ASPU41_05230	COG2244	polysaccharide biosynthetic process
ASPU41_05235	COG1216	Glycosyl transferase, family 2
ASPU41_05245	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ASPU41_05250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ASPU41_05255	COG0673	inositol 2-dehydrogenase activity
ASPU41_05260	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ASPU41_05265	COG1597	lipid kinase activity
ASPU41_05275	COG1414	Transcriptional regulator
ASPU41_05280	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ASPU41_05295	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ASPU41_05305	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ASPU41_05310	COG3485	protocatechuate 3,4-dioxygenase
ASPU41_05315	COG3485	protocatechuate 3,4-dioxygenase
ASPU41_05320	COG3185	4-Hydroxyphenylpyruvate dioxygenase
ASPU41_05325	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ASPU41_05330	COG1414	Transcriptional regulator
ASPU41_05335	COG0477	Major facilitator Superfamily
ASPU41_05340	COG1793	dna ligase
ASPU41_05385	COG1937	Protein conserved in bacteria
ASPU41_05410	COG0697	spore germination
ASPU41_05430	COG0534	Mate efflux family protein
ASPU41_05435	COG2259	Doxx family
ASPU41_05440	COG1607	acyl-coa hydrolase
ASPU41_05445	COG0305	Participates in initiation and elongation during chromosome replication
ASPU41_05480	COG0359	binds to the 23S rRNA
ASPU41_05485	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ASPU41_05495	COG0360	Binds together with S18 to 16S ribosomal RNA
ASPU41_05520	COG1362	aminopeptidase activity
ASPU41_05530	COG1113	amino acid transport
ASPU41_05535	COG2197	response regulator
ASPU41_05540	COG4585	Histidine kinase
ASPU41_05550	COG1131	(ABC) transporter
ASPU41_05565	COG0738	Major facilitator superfamily
ASPU41_05575	COG0247	lactate metabolic process
ASPU41_05575	COG0277	FAD linked oxidase domain protein
ASPU41_05580	COG1620	l-lactate permease
ASPU41_05600	COG2197	response regulator
ASPU41_05625	COG0406	alpha-ribazole phosphatase activity
ASPU41_05630	COG0617	tRNA 3'-terminal CCA addition
ASPU41_05650	COG0492	ferredoxin-NADP+ reductase activity
ASPU41_05655	COG3118	belongs to the thioredoxin family
ASPU41_05665	COG1192	Involved in chromosome partitioning
ASPU41_05670	COG0357	Ribosomal RNA small subunit methyltransferase G
ASPU41_05680	COG0706	membrane insertase activity
ASPU41_05685	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ASPU41_05690	COG0594	ribonuclease P activity
ASPU41_05695	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ASPU41_05700	COG0592	DNA-directed DNA polymerase activity
ASPU41_05705	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
ASPU41_05710	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ASPU41_05715	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
ASPU41_05720	COG0187	DNA topoisomerase II activity
ASPU41_05725	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ASPU41_05730	COG3266	domain, Protein
ASPU41_05755	COG1215	transferase activity, transferring glycosyl groups
ASPU41_05770	COG0705	Rhomboid family
ASPU41_05775	COG2818	Glycosylase
ASPU41_05790	COG0515	serine threonine protein kinase
ASPU41_05795	COG0515	serine threonine protein kinase
ASPU41_05800	COG0768	penicillin binding
ASPU41_05815	COG1716	ATPase activity
ASPU41_05820	COG1716	ATPase activity
ASPU41_05855	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ASPU41_05865	COG0346	lactoylglutathione lyase activity
ASPU41_05895	COG4336	lyase activity
ASPU41_05900	COG1914	H( )-stimulated, divalent metal cation uptake system
ASPU41_05905	COG2186	Transcriptional regulator
ASPU41_05910	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ASPU41_05915	COG1984	allophanate hydrolase subunit 2
ASPU41_05920	COG4770	biotin carboxylase activity
ASPU41_05945	COG2076	Multidrug Resistance protein
ASPU41_05950	COG2826	transposase and inactivated derivatives, IS30 family
ASPU41_06060	COG2197	response regulator
ASPU41_06075	COG2801	Transposase and inactivated derivatives
ASPU41_06095	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ASPU41_06100	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ASPU41_06105	COG0698	ribose 5-phosphate isomerase
ASPU41_06110	COG0191	fructose-bisphosphate aldolase activity
ASPU41_06170	COG0647	UMP catabolic process
ASPU41_06175	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ASPU41_06195	COG2826	transposase and inactivated derivatives, IS30 family
ASPU41_06205	COG1064	alcohol dehydrogenase
ASPU41_06225	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASPU41_06235	COG2186	Transcriptional regulator
ASPU41_06240	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ASPU41_06265	COG1024	Enoyl-CoA hydratase
ASPU41_06265	COG1250	3-hydroxyacyl-CoA dehydrogenase
ASPU41_06270	COG1960	acyl-CoA dehydrogenase activity
ASPU41_06275	COG0318	PFAM AMP-dependent synthetase and ligase
ASPU41_06280	COG0183	Belongs to the thiolase family
ASPU41_06285	COG1309	transcriptional regulator
ASPU41_06290	COG2610	gluconate transmembrane transporter activity
ASPU41_06300	COG1028	Short-chain dehydrogenase reductase Sdr
ASPU41_06310	COG0574	Belongs to the PEP-utilizing enzyme family
ASPU41_06310	COG3848	Pyruvate phosphate dikinase
ASPU41_06320	COG2188	Transcriptional regulator
ASPU41_06330	COG0477	Major facilitator Superfamily
ASPU41_06350	COG1113	amino acid transport
ASPU41_06360	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ASPU41_06370	COG1414	Transcriptional regulator
ASPU41_06380	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ASPU41_06380	COG0574	Belongs to the PEP-utilizing enzyme family
ASPU41_06385	COG0574	Belongs to the PEP-utilizing enzyme family
ASPU41_06385	COG3848	Pyruvate phosphate dikinase
ASPU41_06440	COG2847	Copper chaperone PCu(A)C
ASPU41_06455	COG2188	Transcriptional regulator
ASPU41_06470	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ASPU41_06470	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ASPU41_06485	COG0477	Major facilitator Superfamily
ASPU41_06490	COG1609	Transcriptional regulator
ASPU41_06510	COG0076	glutamate decarboxylase activity
ASPU41_06515	COG3486	L-lysine 6-monooxygenase (NADPH) activity
ASPU41_06545	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ASPU41_06550	COG0569	domain protein
ASPU41_06555	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ASPU41_06580	COG2186	Transcriptional regulator
ASPU41_06585	COG2084	Dehydrogenase
ASPU41_06595	COG0656	L-ascorbic acid biosynthetic process
ASPU41_06600	COG0667	Aldo Keto reductase
ASPU41_06610	COG1349	DNA-binding transcription factor activity
ASPU41_06625	COG1879	ABC-type sugar transport system periplasmic component
ASPU41_06635	COG1172	Belongs to the binding-protein-dependent transport system permease family
ASPU41_06645	COG1869	D-ribose catabolic process
ASPU41_06680	COG0561	phosphatase activity
ASPU41_06690	COG0584	glycerophosphoryl diester phosphodiesterase
ASPU41_06695	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ASPU41_06695	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ASPU41_06700	COG0328	RNA-DNA hybrid ribonuclease activity
ASPU41_06700	COG0406	alpha-ribazole phosphatase activity
ASPU41_06705	COG1929	Belongs to the glycerate kinase type-1 family
ASPU41_06720	COG1028	Short-chain dehydrogenase reductase Sdr
ASPU41_06735	COG2233	PERMEase
ASPU41_06740	COG0778	Nitroreductase
ASPU41_06745	COG3706	GGDEF domain
ASPU41_06770	COG0154	amidase activity
ASPU41_06775	COG0425	Belongs to the sulfur carrier protein TusA family
ASPU41_06775	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ASPU41_06790	COG1597	lipid kinase activity
ASPU41_06795	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ASPU41_06800	COG0561	phosphatase activity
ASPU41_06825	COG2272	Belongs to the type-B carboxylesterase lipase family
ASPU41_06845	COG0037	tRNA processing
ASPU41_06855	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ASPU41_06860	COG0302	gtp cyclohydrolase
ASPU41_06865	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ASPU41_06870	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ASPU41_06900	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ASPU41_06920	COG1435	thymidine kinase activity
ASPU41_06925	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ASPU41_06940	COG0542	response to heat
ASPU41_06945	COG0823	Involved in the tonB-independent uptake of proteins
ASPU41_06945	COG1506	peptidase
ASPU41_06950	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ASPU41_06955	COG2376	Dihydroxyacetone kinase
ASPU41_06960	COG1461	Dihydroxyacetone kinase
ASPU41_06965	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
ASPU41_06995	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
ASPU41_07000	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ASPU41_07005	COG0515	serine threonine protein kinase
ASPU41_07005	COG2815	serine threonine protein kinase
ASPU41_07025	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ASPU41_07055	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ASPU41_07070	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ASPU41_07075	COG0306	phosphate transporter
ASPU41_07100	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ASPU41_07130	COG1796	DNA polymerase
ASPU41_07130	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ASPU41_07140	COG2890	protein-(glutamine-N5) methyltransferase activity
ASPU41_07150	COG2261	transglycosylase associated protein
ASPU41_07155	COG0667	Aldo Keto reductase
ASPU41_07160	COG3360	Dodecin
ASPU41_07170	COG1937	Protein conserved in bacteria
ASPU41_07190	COG2610	gluconate transmembrane transporter activity
ASPU41_07215	COG1028	Short-chain dehydrogenase reductase Sdr
ASPU41_07220	COG0477	Major facilitator Superfamily
ASPU41_07240	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
ASPU41_07260	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASPU41_07260	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASPU41_07260	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASPU41_07270	COG1349	DNA-binding transcription factor activity
ASPU41_07280	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ASPU41_07315	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ASPU41_07325	COG1140	nitrate reductase beta subunit
ASPU41_07345	COG2733	membrane
ASPU41_07355	COG3559	Exporter of polyketide antibiotics
ASPU41_07360	COG1131	(ABC) transporter
ASPU41_07435	COG4948	Mandelate Racemase Muconate Lactonizing
ASPU41_07440	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ASPU41_07450	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ASPU41_07460	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ASPU41_07465	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ASPU41_07465	COG0574	Belongs to the PEP-utilizing enzyme family
ASPU41_07480	COG0726	polysaccharide deacetylase
ASPU41_07525	COG0583	DNA-binding transcription factor activity
ASPU41_07530	COG1028	Short-chain dehydrogenase reductase Sdr
ASPU41_07540	COG0604	alcohol dehydrogenase
ASPU41_07555	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ASPU41_07570	COG3263	regulation of cellular component size
ASPU41_07575	COG0010	Belongs to the arginase family
ASPU41_07580	COG2252	PERMEase
ASPU41_07600	COG0574	Belongs to the PEP-utilizing enzyme family
ASPU41_07600	COG3848	Pyruvate phosphate dikinase
ASPU41_07630	COG0697	spore germination
ASPU41_07635	COG0583	DNA-binding transcription factor activity
ASPU41_07675	COG4941	Belongs to the sigma-70 factor family
ASPU41_07685	COG2176	DNA-directed DNA polymerase activity
ASPU41_07725	COG4974	Belongs to the 'phage' integrase family
ASPU41_07745	COG2801	Transposase and inactivated derivatives
ASPU41_07760	COG3387	PFAM Glycoside hydrolase 15-related
ASPU41_07780	COG2226	methyltransferase
ASPU41_07790	COG4134	Bacterial extracellular solute-binding protein
ASPU41_07805	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ASPU41_07815	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ASPU41_07830	COG0785	Cytochrome C biogenesis protein
ASPU41_07840	COG3118	belongs to the thioredoxin family
ASPU41_07860	COG3118	belongs to the thioredoxin family
ASPU41_07865	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASPU41_07875	COG0789	Transcriptional regulator
ASPU41_07890	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ASPU41_07980	COG0596	Alpha beta hydrolase
ASPU41_08015	COG2182	Extracellular solute-binding protein
ASPU41_08035	COG1609	Transcriptional regulator
ASPU41_08055	COG1024	Enoyl-CoA hydratase
ASPU41_08075	COG0477	Major facilitator Superfamily
ASPU41_08090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ASPU41_08095	COG1960	acyl-CoA dehydrogenase activity
ASPU41_08100	COG1278	Cold shock
ASPU41_08105	COG1215	transferase activity, transferring glycosyl groups
ASPU41_08120	COG3848	Pyruvate phosphate dikinase
ASPU41_08120	COG0574	Belongs to the PEP-utilizing enzyme family
ASPU41_08130	COG1063	alcohol dehydrogenase
ASPU41_08140	COG0145	ligase activity
ASPU41_08145	COG4647	ligase activity
ASPU41_08150	COG0145	ligase activity
ASPU41_08155	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
ASPU41_08190	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ASPU41_08210	COG0508	dehydrogenase complex catalyzes the overall conversion of
ASPU41_08215	COG0022	dehydrogenase e1 component
ASPU41_08215	COG0508	dehydrogenase complex catalyzes the overall conversion of
ASPU41_08220	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ASPU41_08225	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ASPU41_08230	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ASPU41_08255	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ASPU41_08255	COG0357	Ribosomal RNA small subunit methyltransferase G
ASPU41_08260	COG0191	fructose-bisphosphate aldolase activity
ASPU41_08280	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ASPU41_08300	COG1832	CoA-binding protein
ASPU41_08315	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ASPU41_08320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ASPU41_08330	COG1116	anion transmembrane transporter activity
ASPU41_08335	COG1832	CoA-binding protein
ASPU41_08340	COG2315	Protein conserved in bacteria
ASPU41_08345	COG4762	Protein conserved in bacteria
ASPU41_08370	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ASPU41_08375	COG0047	phosphoribosylformylglycinamidine synthase activity
ASPU41_08410	COG1846	Transcriptional regulator
ASPU41_08430	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ASPU41_08460	COG0739	heme binding
ASPU41_08460	COG0741	lytic transglycosylase activity
ASPU41_08460	COG1196	nuclear chromosome segregation
ASPU41_08465	COG0386	Belongs to the glutathione peroxidase family
ASPU41_08470	COG1063	alcohol dehydrogenase
ASPU41_08475	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ASPU41_08480	COG0438	transferase activity, transferring glycosyl groups
ASPU41_08505	COG0438	transferase activity, transferring glycosyl groups
ASPU41_08525	COG2807	transmembrane transport
ASPU41_08540	COG1396	sequence-specific DNA binding
ASPU41_08545	COG0028	Belongs to the TPP enzyme family
ASPU41_08555	COG0351	phosphomethylpyrimidine kinase
ASPU41_08560	COG0477	Major facilitator Superfamily
ASPU41_08590	COG0343	queuine tRNA-ribosyltransferase activity
ASPU41_08620	COG3842	ATPase activity
ASPU41_08645	COG1960	acyl-CoA dehydrogenase activity
ASPU41_08665	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ASPU41_08680	COG0564	pseudouridine synthase activity
ASPU41_08705	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ASPU41_08710	COG1201	RNA secondary structure unwinding
ASPU41_08725	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ASPU41_08760	COG4974	Belongs to the 'phage' integrase family
ASPU41_08765	COG0582	viral genome integration into host DNA
ASPU41_08770	COG4974	Belongs to the 'phage' integrase family
ASPU41_08815	COG0667	Aldo Keto reductase
ASPU41_08830	COG0477	Major facilitator Superfamily
ASPU41_08850	COG0438	transferase activity, transferring glycosyl groups
ASPU41_08860	COG0590	tRNA wobble adenosine to inosine editing
ASPU41_08865	COG0671	phosphoesterase, PA-phosphatase related
ASPU41_08870	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ASPU41_08885	COG2205	protein histidine kinase activity
ASPU41_08890	COG0745	RESPONSE REGULATOR receiver
ASPU41_08905	COG2062	phosphohistidine phosphatase, SixA
ASPU41_08925	COG1309	transcriptional regulator
ASPU41_08930	COG1511	domain protein
ASPU41_08955	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
ASPU41_08965	COG1017	nitric oxide dioxygenase activity
ASPU41_08965	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ASPU41_08970	COG1959	2 iron, 2 sulfur cluster binding
ASPU41_08980	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ASPU41_08985	COG0514	ATP-dependent DNA helicase (RecQ)
ASPU41_08990	COG0477	Major facilitator Superfamily
ASPU41_09005	COG1505	serine-type exopeptidase activity
ASPU41_09040	COG1966	Carbon starvation protein
ASPU41_09060	COG0656	L-ascorbic acid biosynthetic process
ASPU41_09085	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ASPU41_09115	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ASPU41_09120	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ASPU41_09140	COG0588	phosphoglycerate mutase activity
ASPU41_09150	COG5002	protein histidine kinase activity
ASPU41_09170	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ASPU41_09175	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ASPU41_09185	COG0215	cysteine-tRNA ligase activity
ASPU41_09220	COG0366	Alpha amylase catalytic
ASPU41_09230	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ASPU41_09260	COG0277	FAD linked oxidase domain protein
ASPU41_09270	COG3842	ATPase activity
ASPU41_09280	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
ASPU41_09315	COG0783	Belongs to the Dps family
ASPU41_09320	COG0477	Major facilitator Superfamily
ASPU41_09330	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ASPU41_09330	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ASPU41_09335	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ASPU41_09340	COG0509	glycine decarboxylation via glycine cleavage system
ASPU41_09345	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ASPU41_09355	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
ASPU41_09375	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ASPU41_09390	COG1278	Cold shock
ASPU41_09400	COG0459	protein refolding
ASPU41_09415	COG2205	protein histidine kinase activity
ASPU41_09420	COG0745	RESPONSE REGULATOR receiver
ASPU41_09440	COG1278	Cold shock
ASPU41_09450	COG2814	Major facilitator Superfamily
ASPU41_09465	COG0739	heme binding
ASPU41_09480	COG0746	molybdenum cofactor guanylyltransferase activity
ASPU41_09495	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ASPU41_09515	COG0488	(ABC) transporter
ASPU41_09520	COG1132	(ABC) transporter
ASPU41_09570	COG0483	inositol monophosphate 1-phosphatase activity
ASPU41_09595	COG0045	succinate-CoA ligase (ADP-forming) activity
ASPU41_09610	COG0640	Transcriptional regulator
ASPU41_09625	COG1942	4-Oxalocrotonate Tautomerase
ASPU41_09630	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ASPU41_09640	COG3962	Belongs to the TPP enzyme family
ASPU41_09655	COG0673	inositol 2-dehydrogenase activity
ASPU41_09660	COG1082	Xylose isomerase domain protein TIM barrel
ASPU41_09665	COG2814	Major facilitator Superfamily
ASPU41_09675	COG2814	Major facilitator Superfamily
ASPU41_09685	COG1172	Belongs to the binding-protein-dependent transport system permease family
ASPU41_09695	COG0673	inositol 2-dehydrogenase activity
ASPU41_09705	COG0673	inositol 2-dehydrogenase activity
ASPU41_09710	COG3718	enzyme involved in inositol metabolism
ASPU41_09715	COG1609	Transcriptional regulator
ASPU41_09720	COG0584	glycerophosphoryl diester phosphodiesterase
ASPU41_09725	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ASPU41_09755	COG1396	sequence-specific DNA binding
ASPU41_09770	COG0028	Belongs to the TPP enzyme family
ASPU41_09815	COG1401	restriction endodeoxyribonuclease activity
ASPU41_09860	COG1063	alcohol dehydrogenase
ASPU41_09865	COG1902	pentaerythritol trinitrate reductase activity
ASPU41_09890	COG0405	Gamma-glutamyltransferase
ASPU41_09920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ASPU41_09945	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ASPU41_10015	COG4152	abc transporter atp-binding protein
ASPU41_10025	COG1254	Belongs to the acylphosphatase family
ASPU41_10030	COG0514	ATP-dependent DNA helicase (RecQ)
ASPU41_10040	COG3835	regulator
ASPU41_10070	COG0477	Major facilitator Superfamily
ASPU41_10095	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ASPU41_10105	COG2072	flavoprotein involved in K transport
ASPU41_10135	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ASPU41_10160	COG1175	transmembrane transport
ASPU41_10175	COG3684	Belongs to the aldolase LacD family
ASPU41_10185	COG0673	inositol 2-dehydrogenase activity
ASPU41_10190	COG1349	DNA-binding transcription factor activity
ASPU41_10245	COG1302	Protein conserved in bacteria
ASPU41_10275	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ASPU41_10305	COG1597	lipid kinase activity
ASPU41_10310	COG0028	Belongs to the TPP enzyme family
ASPU41_10320	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ASPU41_10325	COG1113	amino acid transport
ASPU41_10345	COG2826	transposase and inactivated derivatives, IS30 family
ASPU41_10375	COG3540	Alkaline phosphatase
ASPU41_10395	COG4942	peptidase
ASPU41_10405	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ASPU41_10435	COG2072	flavoprotein involved in K transport
ASPU41_10450	COG4638	Rieske (2fe-2S)
ASPU41_10455	COG0583	DNA-binding transcription factor activity
ASPU41_10460	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ASPU41_10470	COG0302	gtp cyclohydrolase
ASPU41_10490	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ASPU41_10515	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ASPU41_10555	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
ASPU41_10610	COG0346	lactoylglutathione lyase activity
ASPU41_10620	COG1278	Cold shock
ASPU41_10680	COG1473	amidohydrolase
ASPU41_10700	COG1609	Transcriptional regulator
ASPU41_10715	COG3300	MHYT domain
ASPU41_10715	COG5001	Diguanylate cyclase
ASPU41_10720	COG5001	Diguanylate cyclase
ASPU41_10720	COG3300	MHYT domain
ASPU41_10730	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ASPU41_10730	COG0438	transferase activity, transferring glycosyl groups
ASPU41_10750	COG0318	PFAM AMP-dependent synthetase and ligase
ASPU41_10755	COG1028	Short-chain dehydrogenase reductase Sdr
ASPU41_10770	COG0477	Major facilitator Superfamily
ASPU41_10795	COG0477	Major facilitator Superfamily
ASPU41_10800	COG0138	bifunctional purine biosynthesis protein purh
ASPU41_10810	COG2838	Isocitrate dehydrogenase
ASPU41_10825	COG0515	serine threonine protein kinase
ASPU41_10825	COG2815	serine threonine protein kinase
ASPU41_10835	COG0673	inositol 2-dehydrogenase activity
ASPU41_10845	COG1136	(ABC) transporter
ASPU41_10855	COG4213	ABC transporter substrate-binding protein
ASPU41_10895	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ASPU41_10900	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ASPU41_10930	COG0180	Tryptophanyl-tRNA synthetase
ASPU41_10950	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ASPU41_10965	COG2009	succinate dehydrogenase
ASPU41_10975	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ASPU41_10975	COG1473	amidohydrolase
ASPU41_10980	COG1846	Transcriptional regulator
ASPU41_10985	COG1764	response to oxidative stress
ASPU41_10990	COG2130	NADP-dependent
ASPU41_10995	COG1744	ABC transporter substrate-binding protein PnrA-like
ASPU41_11035	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ASPU41_11040	COG3956	TIGRFAM MazG family protein
ASPU41_11045	COG0148	phosphopyruvate hydratase activity
ASPU41_11070	COG1252	NADH dehydrogenase
ASPU41_11105	COG0559	Belongs to the binding-protein-dependent transport system permease family
ASPU41_11115	COG0183	Belongs to the thiolase family
ASPU41_11120	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ASPU41_11135	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ASPU41_11145	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ASPU41_11155	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ASPU41_11165	COG1331	Highly conserved protein containing a thioredoxin domain
ASPU41_11175	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ASPU41_11180	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ASPU41_11215	COG0114	fumarate hydratase activity
ASPU41_11220	COG0288	reversible hydration of carbon dioxide
ASPU41_11230	COG1494	fructose-1,6-bisphosphatase
ASPU41_11245	COG1482	cell wall glycoprotein biosynthetic process
ASPU41_11305	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ASPU41_11310	COG1376	ErfK ybiS ycfS ynhG family protein
ASPU41_11350	COG0714	Associated with various cellular activities
ASPU41_11355	COG0084	hydrolase, TatD family'
ASPU41_11360	COG3583	domain protein
ASPU41_11365	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ASPU41_11370	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ASPU41_11375	COG0488	(ABC) transporter
ASPU41_11390	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ASPU41_11400	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ASPU41_11405	COG0193	aminoacyl-tRNA hydrolase activity
ASPU41_11415	COG2197	response regulator
ASPU41_11435	COG0822	iron-sulfur transferase activity
ASPU41_11450	COG0702	epimerase
ASPU41_11475	COG0446	pyridine nucleotide-disulphide oxidoreductase
ASPU41_11490	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ASPU41_11500	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ASPU41_11505	COG1959	2 iron, 2 sulfur cluster binding
ASPU41_11570	COG0243	molybdopterin cofactor binding
ASPU41_11575	COG2223	nitrite transmembrane transporter activity
ASPU41_11580	COG0477	Major facilitator Superfamily
ASPU41_11590	COG4770	biotin carboxylase activity
ASPU41_11595	COG0424	maF-like protein
ASPU41_11610	COG2409	Drug exporters of the RND superfamily
ASPU41_11640	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ASPU41_11645	COG1028	Short-chain dehydrogenase reductase Sdr
ASPU41_11650	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ASPU41_11650	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ASPU41_11670	COG0714	Associated with various cellular activities
ASPU41_11690	COG0631	protein serine/threonine phosphatase activity
ASPU41_11710	COG1674	ftsk spoiiie
ASPU41_11775	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ASPU41_11800	COG4565	transcriptional regulatory protein
ASPU41_11810	COG2851	Citrate transporter
ASPU41_11815	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ASPU41_11820	COG0154	amidase activity
ASPU41_11825	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ASPU41_11840	COG1063	alcohol dehydrogenase
ASPU41_11855	COG1228	amidohydrolase
ASPU41_11875	COG2873	o-acetylhomoserine
ASPU41_11880	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ASPU41_11910	COG2755	lipolytic protein G-D-S-L family
ASPU41_11915	COG0400	carboxylic ester hydrolase activity
ASPU41_11930	COG0423	glycine-tRNA ligase activity
ASPU41_11940	COG2031	fatty acid transporter
ASPU41_11945	COG0204	Acyl-transferase
ASPU41_11960	COG0277	FAD linked oxidase domain protein
ASPU41_11980	COG0358	DNA primase activity
ASPU41_12000	COG2814	Major facilitator Superfamily
ASPU41_12020	COG0297	glycogen (starch) synthase activity
ASPU41_12040	COG0052	Belongs to the universal ribosomal protein uS2 family
ASPU41_12045	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ASPU41_12050	COG0528	UMP kinase activity
ASPU41_12055	COG0233	cytoplasmic translational termination
ASPU41_12060	COG0575	Belongs to the CDS family
ASPU41_12070	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ASPU41_12085	COG3275	phosphorelay sensor kinase activity
ASPU41_12095	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ASPU41_12100	COG1522	sequence-specific DNA binding
ASPU41_12110	COG0022	dehydrogenase e1 component
ASPU41_12115	COG0508	dehydrogenase complex catalyzes the overall conversion of
ASPU41_12125	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ASPU41_12135	COG1960	acyl-CoA dehydrogenase activity
ASPU41_12160	COG4565	transcriptional regulatory protein
ASPU41_12165	COG3290	protein histidine kinase activity
ASPU41_12190	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ASPU41_12195	COG0750	zinc metalloprotease
ASPU41_12215	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ASPU41_12225	COG0442	prolyl-tRNA aminoacylation
ASPU41_12255	COG0779	Required for maturation of 30S ribosomal subunits
ASPU41_12270	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ASPU41_12275	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ASPU41_12285	COG0590	tRNA wobble adenosine to inosine editing
ASPU41_12290	COG3118	belongs to the thioredoxin family
ASPU41_12310	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ASPU41_12360	COG3483	tryptophan 2,3-dioxygenase activity
ASPU41_12370	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ASPU41_12375	COG1185	polyribonucleotide nucleotidyltransferase activity
ASPU41_12380	COG0612	Peptidase, M16
ASPU41_12395	COG0411	ABC transporter
ASPU41_12400	COG0410	ABC transporter
ASPU41_12460	COG0521	Mo-molybdopterin cofactor biosynthetic process
ASPU41_12470	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ASPU41_12490	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ASPU41_12490	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ASPU41_12495	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ASPU41_12500	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ASPU41_12505	COG1674	ftsk spoiiie
ASPU41_12515	COG1546	Belongs to the CinA family
ASPU41_12515	COG1058	Belongs to the CinA family
ASPU41_12520	COG1396	sequence-specific DNA binding
ASPU41_12535	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ASPU41_12540	COG2137	regulation of response to DNA damage stimulus
ASPU41_12545	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ASPU41_12550	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ASPU41_12555	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ASPU41_12560	COG2813	Specifically methylates the guanine in position
ASPU41_12565	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ASPU41_12575	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ASPU41_12585	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ASPU41_12590	COG0131	Imidazoleglycerol-phosphate dehydratase
ASPU41_12595	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ASPU41_12600	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ASPU41_12620	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ASPU41_12625	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ASPU41_12630	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ASPU41_12635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ASPU41_12640	COG2261	transglycosylase associated protein
ASPU41_12650	COG2814	Major facilitator Superfamily
ASPU41_12660	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ASPU41_12665	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ASPU41_12670	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ASPU41_12720	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ASPU41_12725	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASPU41_12725	COG0072	phenylalanine-tRNA ligase activity
ASPU41_12765	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ASPU41_12770	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ASPU41_12775	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ASPU41_12780	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ASPU41_12785	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ASPU41_12790	COG1438	arginine binding
ASPU41_12795	COG0137	argininosuccinate synthase activity
ASPU41_12800	COG0165	Argininosuccinate lyase
ASPU41_12805	COG0259	pyridoxamine-phosphate oxidase activity
ASPU41_12815	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ASPU41_12815	COG2169	Transcriptional regulator
ASPU41_12825	COG2094	Belongs to the DNA glycosylase MPG family
ASPU41_12835	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ASPU41_12845	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ASPU41_12890	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ASPU41_12895	COG0497	DNA recombination
ASPU41_12900	COG0504	CTP synthase activity
ASPU41_12930	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ASPU41_12935	COG2079	MmgE PrpD family protein
ASPU41_12955	COG3290	protein histidine kinase activity
ASPU41_12970	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ASPU41_12975	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ASPU41_12990	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ASPU41_13000	COG1160	GTP binding
ASPU41_13010	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ASPU41_13015	COG0509	glycine decarboxylation via glycine cleavage system
ASPU41_13045	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ASPU41_13055	COG1940	carbohydrate kinase activity
ASPU41_13080	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ASPU41_13085	COG0515	serine threonine protein kinase
ASPU41_13085	COG2815	serine threonine protein kinase
ASPU41_13090	COG1388	LysM domain
ASPU41_13090	COG3942	CHAP domain
ASPU41_13100	COG0142	geranyltranstransferase activity
ASPU41_13110	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ASPU41_13120	COG2001	Belongs to the MraZ family
ASPU41_13125	COG0275	rRNA processing
ASPU41_13135	COG0768	penicillin binding
ASPU41_13140	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ASPU41_13145	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ASPU41_13150	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ASPU41_13155	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ASPU41_13160	COG0772	Belongs to the SEDS family
ASPU41_13165	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ASPU41_13170	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ASPU41_13180	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ASPU41_13195	COG1799	cell septum assembly
ASPU41_13210	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ASPU41_13235	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ASPU41_13240	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ASPU41_13255	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ASPU41_13260	COG0174	glutamine synthetase
ASPU41_13265	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ASPU41_13290	COG2826	transposase and inactivated derivatives, IS30 family
ASPU41_13305	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ASPU41_13310	COG0321	lipoyl(octanoyl) transferase activity
ASPU41_13325	COG1090	epimerase
ASPU41_13330	COG4946	Tricorn protease homolog
ASPU41_13330	COG0793	Belongs to the peptidase S41A family
ASPU41_13335	COG1764	response to oxidative stress
ASPU41_13345	COG0508	dehydrogenase complex catalyzes the overall conversion of
ASPU41_13350	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASPU41_13355	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ASPU41_13375	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ASPU41_13385	COG0187	DNA topoisomerase II activity
ASPU41_13405	COG1271	oxidase subunit
ASPU41_13410	COG1294	oxidase, subunit
ASPU41_13415	COG4988	ABC transporter
ASPU41_13420	COG0456	acetyltransferase
ASPU41_13430	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ASPU41_13435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ASPU41_13435	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ASPU41_13465	COG0756	dUTP diphosphatase activity
ASPU41_13490	COG0569	domain protein
ASPU41_13495	COG0531	amino acid
ASPU41_13500	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ASPU41_13505	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ASPU41_13510	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ASPU41_13530	COG0667	Aldo Keto reductase
ASPU41_13550	COG3845	ABC transporter
ASPU41_13560	COG1024	Enoyl-CoA hydratase
ASPU41_13560	COG1250	3-hydroxyacyl-CoA dehydrogenase
ASPU41_13565	COG0183	Belongs to the thiolase family
ASPU41_13570	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ASPU41_13595	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASPU41_13605	COG3415	Transposase
ASPU41_13605	COG2801	Transposase and inactivated derivatives
ASPU41_13615	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ASPU41_13680	COG0242	peptide deformylase activity
ASPU41_13685	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ASPU41_13695	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ASPU41_13720	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ASPU41_13725	COG0140	phosphoribosyl-ATP diphosphatase activity
ASPU41_13730	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ASPU41_13735	COG0107	imidazoleglycerol-phosphate synthase activity
ASPU41_13745	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ASPU41_13765	COG0134	indole-3-glycerol-phosphate synthase activity
ASPU41_13770	COG0133	tryptophan synthase activity
ASPU41_13775	COG0159	tryptophan synthase activity
ASPU41_13780	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ASPU41_13785	COG0067	glutamate synthase
ASPU41_13785	COG0069	glutamate synthase activity
ASPU41_13785	COG0070	glutamate synthase
ASPU41_13795	COG0469	pyruvate kinase activity
ASPU41_13815	COG2801	Transposase and inactivated derivatives
ASPU41_13880	COG1028	Short-chain dehydrogenase reductase Sdr
ASPU41_13880	COG3321	synthase
ASPU41_13880	COG0604	alcohol dehydrogenase
ASPU41_13900	COG0179	Fumarylacetoacetate (FAA) hydrolase
ASPU41_13945	COG2072	flavoprotein involved in K transport
ASPU41_13950	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ASPU41_14015	COG1063	alcohol dehydrogenase
ASPU41_14025	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ASPU41_14030	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ASPU41_14045	COG2801	Transposase and inactivated derivatives
ASPU41_14100	COG4974	Belongs to the 'phage' integrase family
ASPU41_14105	COG0582	viral genome integration into host DNA
ASPU41_14110	COG4974	Belongs to the 'phage' integrase family
ASPU41_14120	COG2814	Major facilitator Superfamily
ASPU41_14150	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ASPU41_14160	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ASPU41_14200	COG0438	transferase activity, transferring glycosyl groups
ASPU41_14255	COG5416	Lipopolysaccharide assembly protein A domain
ASPU41_14345	COG1278	Cold shock
ASPU41_14355	COG2963	transposase activity
ASPU41_14360	COG2801	Transposase and inactivated derivatives
ASPU41_14375	COG2409	Drug exporters of the RND superfamily
ASPU41_14380	COG2801	Transposase and inactivated derivatives
ASPU41_14400	COG2801	Transposase and inactivated derivatives
ASPU41_14410	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ASPU41_14420	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ASPU41_14425	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ASPU41_14430	COG2801	Transposase and inactivated derivatives
ASPU41_14485	COG2814	Major facilitator Superfamily
ASPU41_14515	COG1960	acyl-CoA dehydrogenase activity
ASPU41_14530	COG0733	neurotransmitter:sodium symporter activity
ASPU41_14545	COG2188	Transcriptional regulator
ASPU41_14550	COG1620	l-lactate permease
ASPU41_14555	COG0247	lactate metabolic process
ASPU41_14560	COG1139	Iron-sulfur cluster binding protein
ASPU41_14565	COG1556	Lactate utilization protein
ASPU41_14575	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ASPU41_14580	COG0277	FAD linked oxidase domain protein
ASPU41_14585	COG1414	Transcriptional regulator
ASPU41_14590	COG1793	dna ligase
ASPU41_14590	COG3285	dna ligase
ASPU41_14600	COG2124	cytochrome p450
ASPU41_14610	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ASPU41_14615	COG2197	response regulator
ASPU41_14620	COG2814	Major facilitator Superfamily
ASPU41_14625	COG1028	Short-chain dehydrogenase reductase Sdr
ASPU41_14640	COG4638	Rieske (2fe-2S)
ASPU41_14645	COG0583	DNA-binding transcription factor activity
ASPU41_14650	COG3485	protocatechuate 3,4-dioxygenase
ASPU41_14655	COG3135	benzoate transporter
ASPU41_14660	COG1528	Iron-storage protein
ASPU41_14690	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ASPU41_14695	COG1937	Protein conserved in bacteria
ASPU41_14700	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ASPU41_14710	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ASPU41_14715	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ASPU41_14725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ASPU41_14730	COG2814	Major facilitator Superfamily
ASPU41_14735	COG2801	Transposase and inactivated derivatives
ASPU41_14770	COG0861	Integral membrane protein TerC family
ASPU41_14805	COG1846	Transcriptional regulator
ASPU41_14810	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ASPU41_14815	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ASPU41_14815	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ASPU41_14840	COG0412	Dienelactone hydrolase
ASPU41_14865	COG1643	Atp-dependent helicase
ASPU41_14880	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ASPU41_14915	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ASPU41_14950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ASPU41_14965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ASPU41_14990	COG2801	Transposase and inactivated derivatives
ASPU41_15015	COG0667	Aldo Keto reductase
ASPU41_15020	COG1621	beta-fructofuranosidase activity
ASPU41_15040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASPU41_15045	COG0601	transmembrane transport
ASPU41_15050	COG0747	negative chemotaxis
ASPU41_15060	COG1609	Transcriptional regulator
ASPU41_15070	COG1175	transmembrane transport
ASPU41_15075	COG0395	ABC-type sugar transport system, permease component
ASPU41_15080	COG1621	beta-fructofuranosidase activity
ASPU41_15095	COG4974	Belongs to the 'phage' integrase family
ASPU41_15100	COG0582	viral genome integration into host DNA
ASPU41_15105	COG4974	Belongs to the 'phage' integrase family
ASPU41_15120	COG2801	Transposase and inactivated derivatives
ASPU41_15175	COG0009	L-threonylcarbamoyladenylate synthase
ASPU41_15180	COG1174	glycine betaine transport
ASPU41_15190	COG1174	glycine betaine transport
ASPU41_15205	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ASPU41_15205	COG3608	succinylglutamate desuccinylase aspartoacylase
ASPU41_15220	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ASPU41_15230	COG3608	succinylglutamate desuccinylase aspartoacylase
ASPU41_15230	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ASPU41_15250	COG0583	DNA-binding transcription factor activity
ASPU41_15270	COG0318	PFAM AMP-dependent synthetase and ligase
ASPU41_15275	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ASPU41_15295	COG0589	response to stress
ASPU41_15305	COG0179	Fumarylacetoacetate (FAA) hydrolase
ASPU41_15320	COG2814	Major facilitator Superfamily
ASPU41_15325	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASPU41_15340	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ASPU41_15345	COG2050	protein possibly involved in aromatic compounds catabolism
ASPU41_15355	COG4552	Acetyltransferase involved in intracellular survival and related
ASPU41_15360	COG0539	negative regulation of cytoplasmic translation
ASPU41_15375	COG1739	Uncharacterized protein family UPF0029
ASPU41_15380	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ASPU41_15380	COG0237	dephospho-CoA kinase activity
ASPU41_15385	COG0556	nucleotide-excision repair
ASPU41_15390	COG0861	Integral membrane protein TerC family
ASPU41_15420	COG4106	trans-aconitate 2-methyltransferase activity
ASPU41_15425	COG1132	(ABC) transporter
ASPU41_15460	COG0322	excinuclease ABC activity
ASPU41_15465	COG1660	Displays ATPase and GTPase activities
ASPU41_15470	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ASPU41_15475	COG1481	regulation of sporulation
ASPU41_15480	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ASPU41_15485	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ASPU41_15490	COG0126	phosphoglycerate kinase activity
ASPU41_15495	COG0149	triose-phosphate isomerase activity
ASPU41_15500	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ASPU41_15510	COG0363	glucosamine-6-phosphate deaminase activity
ASPU41_15525	COG0166	Belongs to the GPI family
ASPU41_15530	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ASPU41_15540	COG0109	protoheme IX farnesyltransferase activity
ASPU41_15545	COG1612	heme a metabolic process
ASPU41_15550	COG0842	Transport permease protein
ASPU41_15555	COG1131	(ABC) transporter
ASPU41_15580	COG0396	ATPase activity
ASPU41_15585	COG2151	metal-sulfur cluster biosynthetic enzyme
ASPU41_15595	COG0318	PFAM AMP-dependent synthetase and ligase
ASPU41_15610	COG1122	ATPase activity
ASPU41_15615	COG1268	BioY protein
ASPU41_15620	COG0488	(ABC) transporter
ASPU41_15630	COG2801	Transposase and inactivated derivatives
ASPU41_15630	COG3415	Transposase
ASPU41_15665	COG1028	Short-chain dehydrogenase reductase Sdr
ASPU41_15690	COG1028	Short-chain dehydrogenase reductase Sdr
ASPU41_15695	COG0560	Phosphoserine phosphatase
ASPU41_15695	COG3830	Belongs to the UPF0237 family
ASPU41_15700	COG1119	ATPase activity
ASPU41_15715	COG0254	rRNA binding
ASPU41_15730	COG2855	membrane
ASPU41_15780	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ASPU41_15785	COG0297	glycogen (starch) synthase activity
ASPU41_15800	COG0183	Belongs to the thiolase family
ASPU41_15805	COG1028	Short-chain dehydrogenase reductase Sdr
ASPU41_15820	COG0435	Glutathione S-transferase
ASPU41_15830	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ASPU41_15885	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ASPU41_15905	COG0656	L-ascorbic acid biosynthetic process
ASPU41_15910	COG1968	undecaprenyl-diphosphatase activity
ASPU41_15915	COG0215	cysteine-tRNA ligase activity
ASPU41_15925	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ASPU41_15930	COG1994	Peptidase M50
ASPU41_15930	COG0517	IMP dehydrogenase activity
ASPU41_15940	COG1222	aaa ATPase
ASPU41_15945	COG4122	O-methyltransferase activity
ASPU41_15955	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
ASPU41_15960	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
ASPU41_15965	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
ASPU41_15970	COG0545	Peptidyl-prolyl cis-trans isomerase
ASPU41_15990	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ASPU41_15995	COG0805	protein transport
ASPU41_16000	COG4581	dead DEAH box helicase
ASPU41_16005	COG1574	metal-dependent hydrolase with the TIM-barrel fold
ASPU41_16010	COG1216	Glycosyl transferase, family 2
ASPU41_16035	COG0823	Involved in the tonB-independent uptake of proteins
ASPU41_16035	COG1506	peptidase
ASPU41_16035	COG4946	Tricorn protease homolog
ASPU41_16040	COG0242	peptide deformylase activity
ASPU41_16065	COG3424	synthase
ASPU41_16115	COG0723	plastoquinol--plastocyanin reductase activity
ASPU41_16115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ASPU41_16145	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ASPU41_16150	COG1845	cytochrome c oxidase, subunit III
ASPU41_16155	COG2010	Cytochrome c
ASPU41_16160	COG0723	plastoquinol--plastocyanin reductase activity
ASPU41_16165	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ASPU41_16170	COG2188	Transcriptional regulator
ASPU41_16185	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ASPU41_16190	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ASPU41_16200	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ASPU41_16210	COG0167	dihydroorotate dehydrogenase activity
ASPU41_16220	COG2267	carboxylic ester hydrolase activity
ASPU41_16225	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ASPU41_16230	COG1381	Involved in DNA repair and RecF pathway recombination
ASPU41_16235	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ASPU41_16240	COG3590	peptidase
ASPU41_16245	COG5492	domain, Protein
ASPU41_16245	COG4932	domain protein
ASPU41_16255	COG1316	TRANSCRIPTIONal
ASPU41_16260	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ASPU41_16270	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ASPU41_16285	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ASPU41_16290	COG0484	heat shock protein binding
ASPU41_16295	COG1420	regulation of RNA biosynthetic process
ASPU41_16310	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ASPU41_16315	COG0481	GTPase activity
ASPU41_16330	COG0268	Binds directly to 16S ribosomal RNA
ASPU41_16365	COG2132	Multicopper oxidase
ASPU41_16445	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
ASPU41_16450	COG2217	Heavy metal translocating P-type atpase
ASPU41_16465	COG1937	Protein conserved in bacteria
ASPU41_16480	COG1388	LysM domain
ASPU41_16480	COG3103	Sh3 type 3 domain protein
ASPU41_16480	COG0791	NLP P60 protein
ASPU41_16505	COG0785	Cytochrome C biogenesis protein
ASPU41_16510	COG2132	Multicopper oxidase
ASPU41_16555	COG0739	heme binding
ASPU41_16570	COG0531	amino acid
ASPU41_16585	COG2217	Heavy metal translocating P-type atpase
ASPU41_16650	COG4974	Belongs to the 'phage' integrase family
ASPU41_16660	COG2161	toxin-antitoxin pair type II binding
ASPU41_16690	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ASPU41_16735	COG2801	Transposase and inactivated derivatives
ASPU41_16745	COG0596	Alpha beta hydrolase
ASPU41_16805	COG1307	EDD domain protein, DegV family
ASPU41_16810	COG0495	leucyl-tRNA aminoacylation
ASPU41_16830	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ASPU41_16835	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ASPU41_16840	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ASPU41_16845	COG2390	Transcriptional regulator
ASPU41_16850	COG0656	L-ascorbic acid biosynthetic process
ASPU41_16870	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ASPU41_16880	COG1758	RNA polymerase activity
ASPU41_16885	COG0194	GDP metabolic process
ASPU41_16890	COG0194	GDP metabolic process
ASPU41_16895	COG0284	orotidine-5'-phosphate decarboxylase activity
ASPU41_16900	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ASPU41_16905	COG0505	Belongs to the CarA family
ASPU41_16915	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ASPU41_16920	COG0540	Belongs to the ATCase OTCase family
ASPU41_16925	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ASPU41_16935	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ASPU41_16940	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ASPU41_16950	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ASPU41_16960	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ASPU41_16965	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ASPU41_16980	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ASPU41_16995	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ASPU41_17025	COG1846	Transcriptional regulator
ASPU41_17050	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ASPU41_17070	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ASPU41_17080	COG0124	histidyl-tRNA synthetase
ASPU41_17090	COG1196	nuclear chromosome segregation
ASPU41_17100	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ASPU41_17105	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ASPU41_17110	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ASPU41_17120	COG2255	four-way junction helicase activity
ASPU41_17125	COG0632	four-way junction helicase activity
ASPU41_17130	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ASPU41_17135	COG0217	transcriptional regulatory protein
ASPU41_17140	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ASPU41_17145	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ASPU41_17155	COG0454	-acetyltransferase
ASPU41_17180	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ASPU41_17195	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ASPU41_17200	COG0587	DNA-directed DNA polymerase activity
ASPU41_17215	COG0077	Prephenate dehydratase
ASPU41_17215	COG1605	Chorismate mutase
ASPU41_17225	COG0446	pyridine nucleotide-disulphide oxidoreductase
ASPU41_17230	COG2135	peptidase activity
ASPU41_17290	COG0586	Pfam SNARE associated Golgi protein
ASPU41_17365	COG0405	Gamma-glutamyltransferase
ASPU41_17380	COG1132	(ABC) transporter
ASPU41_17390	COG0297	glycogen (starch) synthase activity
ASPU41_17395	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ASPU41_17410	COG1253	flavin adenine dinucleotide binding
ASPU41_17445	COG2826	transposase and inactivated derivatives, IS30 family
ASPU41_17460	COG3384	dioxygenase
ASPU41_17475	COG3540	Alkaline phosphatase
ASPU41_17500	COG1196	nuclear chromosome segregation
ASPU41_17505	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ASPU41_17510	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ASPU41_17515	COG1780	Probably involved in ribonucleotide reductase function
ASPU41_17525	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ASPU41_17545	COG1012	belongs to the aldehyde dehydrogenase family
ASPU41_17575	COG1846	Transcriptional regulator
ASPU41_17575	COG1940	carbohydrate kinase activity
ASPU41_17580	COG2813	Specifically methylates the guanine in position
ASPU41_17590	COG2824	Alkylphosphonate utilization operon protein PhnA
ASPU41_17625	COG0799	negative regulation of ribosome biogenesis
ASPU41_17635	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ASPU41_17645	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ASPU41_17650	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ASPU41_17655	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ASPU41_17660	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ASPU41_17665	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ASPU41_17670	COG0352	thiamine-phosphate diphosphorylase activity
ASPU41_17670	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ASPU41_17670	COG0351	phosphomethylpyrimidine kinase
ASPU41_17675	COG1530	ribonuclease E activity
ASPU41_17685	COG0105	UTP biosynthetic process
ASPU41_17695	COG0285	dihydrofolate synthase activity
ASPU41_17700	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ASPU41_17715	COG1115	amino acid carrier protein
ASPU41_17720	COG0525	valine-tRNA ligase activity
ASPU41_17725	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ASPU41_17730	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ASPU41_17735	COG0740	serine-type endopeptidase activity
ASPU41_17740	COG0740	serine-type endopeptidase activity
ASPU41_17745	COG0544	peptidyl-prolyl cis-trans isomerase activity
ASPU41_17785	COG0668	transmembrane transport
ASPU41_17805	COG1946	Acyl-CoA thioesterase
ASPU41_17825	COG5416	Lipopolysaccharide assembly protein A domain
ASPU41_17865	COG0242	peptide deformylase activity
ASPU41_17870	COG0596	Alpha beta hydrolase
ASPU41_17875	COG2326	polyphosphate kinase activity
ASPU41_17920	COG3022	response to hydroperoxide
ASPU41_17930	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ASPU41_17935	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASPU41_17945	COG1045	serine acetyltransferase
ASPU41_17950	COG1028	Short-chain dehydrogenase reductase Sdr
ASPU41_17955	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ASPU41_17965	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ASPU41_18005	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ASPU41_18020	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ASPU41_18025	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ASPU41_18030	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ASPU41_18040	COG4974	Belongs to the 'phage' integrase family
ASPU41_18160	COG2826	transposase and inactivated derivatives, IS30 family
ASPU41_18195	COG0792	nuclease activity
ASPU41_18205	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ASPU41_18215	COG0681	Belongs to the peptidase S26 family
ASPU41_18220	COG0335	large ribosomal subunit rRNA binding
ASPU41_18225	COG0336	Belongs to the RNA methyltransferase TrmD family
ASPU41_18230	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ASPU41_18235	COG1837	Belongs to the UPF0109 family
ASPU41_18240	COG0228	four-way junction DNA binding
ASPU41_18250	COG2514	catechol 2,3-dioxygenase activity
ASPU41_18265	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ASPU41_18280	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ASPU41_18295	COG2814	Major facilitator Superfamily
ASPU41_18350	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ASPU41_18355	COG0571	ribonuclease III activity
ASPU41_18360	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ASPU41_18375	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ASPU41_18380	COG0300	oxidoreductase activity
ASPU41_18400	COG0742	ribosomal rna small subunit methyltransferase
ASPU41_18410	COG1461	Dihydroxyacetone kinase
ASPU41_18425	COG1088	dTDP-glucose 4,6-dehydratase activity
ASPU41_18430	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ASPU41_18440	COG1181	Belongs to the D-alanine--D-alanine ligase family
ASPU41_18445	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ASPU41_18455	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ASPU41_18460	COG0066	3-isopropylmalate dehydratase activity
ASPU41_18465	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ASPU41_18470	COG1414	Transcriptional regulator
ASPU41_18510	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ASPU41_18515	COG0179	Fumarylacetoacetate (FAA) hydrolase
ASPU41_18530	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ASPU41_18535	COG0473	3-isopropylmalate dehydrogenase activity
ASPU41_18555	COG1136	(ABC) transporter
ASPU41_18555	COG0577	efflux transmembrane transporter activity
ASPU41_18565	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ASPU41_18570	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ASPU41_18575	COG0440	acetolactate synthase activity
ASPU41_18585	COG0129	dihydroxy-acid dehydratase activity
ASPU41_18590	COG0583	DNA-binding transcription factor activity
ASPU41_18645	COG0747	negative chemotaxis
ASPU41_18650	COG0579	oxidoreductase
ASPU41_18655	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ASPU41_18670	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ASPU41_18680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ASPU41_18685	COG1846	Transcriptional regulator
ASPU41_18690	COG1305	Transglutaminase-like
ASPU41_18710	COG1104	cysteine desulfurase activity
ASPU41_18725	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ASPU41_18740	COG1113	amino acid transport
ASPU41_18750	COG0022	dehydrogenase e1 component
ASPU41_18755	COG0508	dehydrogenase complex catalyzes the overall conversion of
ASPU41_18780	COG0477	Major facilitator Superfamily
ASPU41_18810	COG0419	ATPase involved in DNA repair
ASPU41_18815	COG0420	3'-5' exonuclease activity
ASPU41_18840	COG0586	Pfam SNARE associated Golgi protein
ASPU41_18845	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ASPU41_18850	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ASPU41_18855	COG1234	tRNA 3'-trailer cleavage
ASPU41_18860	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ASPU41_18870	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ASPU41_18880	COG1335	isochorismatase
ASPU41_18900	COG0363	glucosamine-6-phosphate deaminase activity
ASPU41_18915	COG1902	pentaerythritol trinitrate reductase activity
ASPU41_18945	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
ASPU41_18955	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ASPU41_18960	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ASPU41_18970	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ASPU41_18975	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ASPU41_18980	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ASPU41_18985	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ASPU41_18990	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ASPU41_18995	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ASPU41_19000	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ASPU41_19005	COG0356	it plays a direct role in the translocation of protons across the membrane
ASPU41_19015	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ASPU41_19020	COG1086	Polysaccharide biosynthesis protein
ASPU41_19040	COG2890	protein-(glutamine-N5) methyltransferase activity
ASPU41_19045	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ASPU41_19055	COG0083	homoserine kinase activity
ASPU41_19060	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ASPU41_19065	COG0460	homoserine dehydrogenase
ASPU41_19070	COG0019	diaminopimelate decarboxylase activity
ASPU41_19075	COG0018	arginyl-trna synthetase
ASPU41_19100	COG0706	membrane insertase activity
ASPU41_19125	COG1643	Atp-dependent helicase
ASPU41_19130	COG0537	adenosine 5'-monophosphoramidase activity
ASPU41_19135	COG1064	alcohol dehydrogenase
ASPU41_19145	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ASPU41_19175	COG1121	(ABC) transporter
ASPU41_19190	COG1253	flavin adenine dinucleotide binding
ASPU41_19200	COG0508	dehydrogenase complex catalyzes the overall conversion of
ASPU41_19200	COG0567	Dehydrogenase, E1 component
ASPU41_19225	COG1595	DNA-templated transcription, initiation
ASPU41_19235	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ASPU41_19245	COG0483	inositol monophosphate 1-phosphatase activity
ASPU41_19250	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ASPU41_19265	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ASPU41_19270	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ASPU41_19285	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ASPU41_19290	COG0739	heme binding
ASPU41_19300	COG2884	Cell division ATP-binding protein ftsE
ASPU41_19305	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ASPU41_19390	COG2963	transposase activity
ASPU41_19405	COG1216	Glycosyl transferase, family 2
ASPU41_19445	COG1216	Glycosyl transferase, family 2
ASPU41_19455	COG1674	ftsk spoiiie
ASPU41_19475	COG2902	Dehydrogenase
ASPU41_19510	COG0653	protein targeting
ASPU41_19520	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ASPU41_19525	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ASPU41_19530	COG5401	PFAM Sporulation and spore germination
ASPU41_19535	COG5002	protein histidine kinase activity
ASPU41_19565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASPU41_19580	COG0482	sulfurtransferase activity
ASPU41_19595	COG0697	spore germination
ASPU41_19620	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ASPU41_19625	COG1595	DNA-templated transcription, initiation
ASPU41_19635	COG3265	gluconokinase activity
ASPU41_19645	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ASPU41_19655	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ASPU41_19665	COG1842	Phage shock protein A
ASPU41_19670	COG0415	Belongs to the DNA photolyase family
ASPU41_19685	COG1615	UPF0182 protein
ASPU41_19690	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ASPU41_19710	COG2816	NAD+ diphosphatase activity
ASPU41_19720	COG0210	DNA helicase
ASPU41_19745	COG2011	ABC-type metal ion transport system permease component
ASPU41_19755	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ASPU41_19765	COG0113	porphobilinogen synthase activity
ASPU41_19775	COG0181	hydroxymethylbilane synthase activity
ASPU41_19800	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ASPU41_19805	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ASPU41_19835	COG2022	thiamine diphosphate biosynthetic process
ASPU41_19850	COG0352	thiamine-phosphate diphosphorylase activity
ASPU41_19865	COG0513	Belongs to the DEAD box helicase family
ASPU41_19870	COG2189	Belongs to the N(4) N(6)-methyltransferase family
ASPU41_19875	COG0613	PHP domain protein
ASPU41_19880	COG0006	proline dipeptidase activity
ASPU41_19890	COG2239	Acts as a magnesium transporter
ASPU41_19900	COG0489	protein tyrosine kinase activity
ASPU41_19900	COG2151	metal-sulfur cluster biosynthetic enzyme
ASPU41_19905	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ASPU41_19915	COG3300	MHYT domain
ASPU41_19915	COG5001	Diguanylate cyclase
ASPU41_19970	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ASPU41_19980	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ASPU41_20030	COG2801	Transposase and inactivated derivatives
ASPU41_20075	COG1475	DNA binding
ASPU41_20080	COG2801	Transposase and inactivated derivatives
ASPU41_20095	COG0582	viral genome integration into host DNA
ASPU41_20100	COG4974	Belongs to the 'phage' integrase family
ASPU41_20115	COG2801	Transposase and inactivated derivatives
ASPU41_20130	COG0542	response to heat
ASPU41_20160	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ASPU41_20205	COG2801	Transposase and inactivated derivatives
ASPU41_20215	COG0129	dihydroxy-acid dehydratase activity
ASPU41_20255	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ASPU41_20290	COG3103	Sh3 type 3 domain protein
ASPU41_20290	COG1388	LysM domain
ASPU41_20290	COG0791	NLP P60 protein
ASPU41_20325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ASPU41_20350	COG2801	Transposase and inactivated derivatives
ASPU41_20395	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ASPU41_20415	COG0656	L-ascorbic acid biosynthetic process
ASPU41_20420	COG0667	Aldo Keto reductase
ASPU41_20460	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ASPU41_20485	COG2188	Transcriptional regulator
ASPU41_20490	COG0154	amidase activity
ASPU41_20505	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ASPU41_20510	COG1012	belongs to the aldehyde dehydrogenase family
ASPU41_20610	COG1192	Involved in chromosome partitioning
ASPU41_20640	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ASPU41_20675	COG2801	Transposase and inactivated derivatives
ASPU41_20690	COG2801	Transposase and inactivated derivatives
ASPU41_20700	COG0582	viral genome integration into host DNA
ASPU41_20705	COG4974	Belongs to the 'phage' integrase family
ASPU41_20730	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ASPU41_20740	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ASPU41_20755	COG1253	flavin adenine dinucleotide binding
ASPU41_20770	COG1192	Involved in chromosome partitioning
ASPU41_20795	COG0542	response to heat
ASPU41_20825	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ASPU41_20990	COG2267	carboxylic ester hydrolase activity
ASPU41_21030	COG2801	Transposase and inactivated derivatives
ASPU41_21055	COG0129	dihydroxy-acid dehydratase activity
ASPU41_21085	COG0861	Integral membrane protein TerC family
ASPU41_21095	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ASPU41_21100	COG0861	Integral membrane protein TerC family
ASPU41_21125	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ASPU41_21160	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ASPU41_21185	COG0542	response to heat
ASPU41_21200	COG0386	Belongs to the glutathione peroxidase family
ASPU41_21205	COG1760	l-serine dehydratase
ASPU41_21235	COG0477	Major facilitator Superfamily
ASPU41_21420	COG0346	lactoylglutathione lyase activity
ASPU41_21440	COG1192	Involved in chromosome partitioning
ASPU41_21480	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ASPU41_21485	COG0129	dihydroxy-acid dehydratase activity
ASPU41_21510	COG0861	Integral membrane protein TerC family
ASPU41_21520	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ASPU41_21525	COG0861	Integral membrane protein TerC family
ASPU41_21550	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ASPU41_21585	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ASPU41_21615	COG1192	Involved in chromosome partitioning
ASPU41_21700	COG0741	lytic transglycosylase activity
ASPU41_21770	COG0084	hydrolase, TatD family'
ASPU41_21800	COG0629	single-stranded DNA binding