locus-tag	class	description
OIT41_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OIT41_00010	COG0592	DNA-directed DNA polymerase activity
OIT41_00015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
OIT41_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OIT41_00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
OIT41_00030	COG0187	DNA topoisomerase II activity
OIT41_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OIT41_00040	COG3266	domain, Protein
OIT41_00065	COG1215	transferase activity, transferring glycosyl groups
OIT41_00105	COG0640	Transcriptional regulator
OIT41_00110	COG2818	Glycosylase
OIT41_00120	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OIT41_00125	COG1595	DNA-templated transcription, initiation
OIT41_00130	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OIT41_00140	COG3764	Sortase (surface protein transpeptidase)
OIT41_00150	COG2815	serine threonine protein kinase
OIT41_00150	COG0515	serine threonine protein kinase
OIT41_00155	COG0515	serine threonine protein kinase
OIT41_00160	COG0768	penicillin binding
OIT41_00175	COG1716	ATPase activity
OIT41_00225	COG1609	Transcriptional regulator
OIT41_00230	COG0659	secondary active sulfate transmembrane transporter activity
OIT41_00255	COG0561	phosphatase activity
OIT41_00280	COG0584	glycerophosphoryl diester phosphodiesterase
OIT41_00285	COG4941	Belongs to the sigma-70 factor family
OIT41_00295	COG1929	Belongs to the glycerate kinase type-1 family
OIT41_00300	COG1610	YqeY-like protein
OIT41_00305	COG2233	PERMEase
OIT41_00310	COG0778	Nitroreductase
OIT41_00330	COG3104	oligopeptide transport
OIT41_00335	COG0154	amidase activity
OIT41_00340	COG3340	Belongs to the peptidase S51 family
OIT41_00345	COG0425	Belongs to the sulfur carrier protein TusA family
OIT41_00345	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OIT41_00360	COG1597	lipid kinase activity
OIT41_00365	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OIT41_00375	COG0561	phosphatase activity
OIT41_00395	COG2027	D-alanyl-D-alanine carboxypeptidase
OIT41_00405	COG0037	tRNA processing
OIT41_00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OIT41_00420	COG0302	gtp cyclohydrolase
OIT41_00425	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OIT41_00430	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OIT41_00460	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OIT41_00465	COG2814	Major facilitator Superfamily
OIT41_00490	COG1802	Transcriptional regulator
OIT41_00500	COG1960	acyl-CoA dehydrogenase activity
OIT41_00530	COG0596	Alpha beta hydrolase
OIT41_00535	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
OIT41_00555	COG1506	peptidase
OIT41_00555	COG0823	Involved in the tonB-independent uptake of proteins
OIT41_00560	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
OIT41_00570	COG2376	Dihydroxyacetone kinase
OIT41_00575	COG1461	Dihydroxyacetone kinase
OIT41_00590	COG2226	methyltransferase
OIT41_00605	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
OIT41_00615	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OIT41_00620	COG3547	Transposase (IS116 IS110 IS902 family)
OIT41_00650	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OIT41_00655	COG0306	phosphate transporter
OIT41_00675	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OIT41_00680	COG0586	Pfam SNARE associated Golgi protein
OIT41_00685	COG0831	urea catabolic process
OIT41_00690	COG0832	Belongs to the urease beta subunit family
OIT41_00695	COG0804	urea catabolic process
OIT41_00700	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
OIT41_00705	COG0830	nickel cation binding
OIT41_00710	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
OIT41_00715	COG0829	nickel cation binding
OIT41_00720	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
OIT41_00725	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
OIT41_00725	COG1796	DNA polymerase
OIT41_00750	COG0656	L-ascorbic acid biosynthetic process
OIT41_00760	COG0667	Aldo Keto reductase
OIT41_00785	COG3360	Dodecin
OIT41_00795	COG1522	sequence-specific DNA binding
OIT41_00805	COG1012	belongs to the aldehyde dehydrogenase family
OIT41_00810	COG0460	homoserine dehydrogenase
OIT41_00815	COG0833	amino acid
OIT41_00830	COG1414	Transcriptional regulator
OIT41_00845	COG2040	homocysteine
OIT41_00850	COG2186	Transcriptional regulator
OIT41_00935	COG1172	Belongs to the binding-protein-dependent transport system permease family
OIT41_00945	COG1012	belongs to the aldehyde dehydrogenase family
OIT41_00950	COG3962	Belongs to the TPP enzyme family
OIT41_00960	COG0673	inositol 2-dehydrogenase activity
OIT41_00970	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OIT41_00975	COG0673	inositol 2-dehydrogenase activity
OIT41_01015	COG0542	response to heat
OIT41_01025	COG5002	protein histidine kinase activity
OIT41_01030	COG0745	RESPONSE REGULATOR receiver
OIT41_01040	COG0477	Major facilitator Superfamily
OIT41_01045	COG2890	protein-(glutamine-N5) methyltransferase activity
OIT41_01065	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
OIT41_01080	COG3237	CsbD-like
OIT41_01105	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OIT41_01110	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OIT41_01110	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OIT41_01110	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OIT41_01120	COG1349	DNA-binding transcription factor activity
OIT41_01155	COG1129	ABC transporter
OIT41_01160	COG1172	Belongs to the binding-protein-dependent transport system permease family
OIT41_01185	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OIT41_01200	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OIT41_01210	COG1819	glycosyl
OIT41_01230	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
OIT41_01235	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
OIT41_01240	COG1984	allophanate hydrolase subunit 2
OIT41_01245	COG2733	membrane
OIT41_01285	COG4122	O-methyltransferase activity
OIT41_01310	COG1028	Short-chain dehydrogenase reductase Sdr
OIT41_01315	COG3706	GGDEF domain
OIT41_01350	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
OIT41_01370	COG0010	Belongs to the arginase family
OIT41_01375	COG2252	PERMEase
OIT41_01395	COG3848	Pyruvate phosphate dikinase
OIT41_01395	COG0574	Belongs to the PEP-utilizing enzyme family
OIT41_01405	COG1609	Transcriptional regulator
OIT41_01410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OIT41_01435	COG1302	Protein conserved in bacteria
OIT41_01465	COG0366	Alpha amylase catalytic
OIT41_01490	COG1609	Transcriptional regulator
OIT41_01510	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OIT41_01520	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OIT41_01535	COG0415	Belongs to the DNA photolyase family
OIT41_01555	COG1024	Enoyl-CoA hydratase
OIT41_01565	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OIT41_01570	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OIT41_01575	COG1609	Transcriptional regulator
OIT41_01585	COG1175	transmembrane transport
OIT41_01590	COG0395	ABC-type sugar transport system, permease component
OIT41_01600	COG0673	inositol 2-dehydrogenase activity
OIT41_01610	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OIT41_01615	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OIT41_01635	COG0357	Ribosomal RNA small subunit methyltransferase G
OIT41_01635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OIT41_01640	COG0191	fructose-bisphosphate aldolase activity
OIT41_01660	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OIT41_01675	COG1832	CoA-binding protein
OIT41_01685	COG2315	Protein conserved in bacteria
OIT41_01695	COG1653	transport
OIT41_01700	COG1175	transmembrane transport
OIT41_01705	COG0395	ABC-type sugar transport system, permease component
OIT41_01725	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OIT41_01730	COG0047	phosphoribosylformylglycinamidine synthase activity
OIT41_01765	COG1846	Transcriptional regulator
OIT41_01785	COG1131	(ABC) transporter
OIT41_01795	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OIT41_01810	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OIT41_01825	COG1012	belongs to the aldehyde dehydrogenase family
OIT41_01845	COG1196	nuclear chromosome segregation
OIT41_01845	COG0741	lytic transglycosylase activity
OIT41_01845	COG0739	heme binding
OIT41_01850	COG0386	Belongs to the glutathione peroxidase family
OIT41_01855	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OIT41_01895	COG1309	transcriptional regulator
OIT41_01915	COG4702	Belongs to the UPF0303 family
OIT41_01925	COG0823	Involved in the tonB-independent uptake of proteins
OIT41_01945	COG0673	inositol 2-dehydrogenase activity
OIT41_01955	COG0395	ABC-type sugar transport system, permease component
OIT41_01995	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OIT41_02040	COG1131	(ABC) transporter
OIT41_02050	COG0343	queuine tRNA-ribosyltransferase activity
OIT41_02070	COG3547	Transposase (IS116 IS110 IS902 family)
OIT41_02100	COG1960	acyl-CoA dehydrogenase activity
OIT41_02105	COG3254	rhamnose metabolic process
OIT41_02110	COG0477	Major facilitator Superfamily
OIT41_02115	COG1609	Transcriptional regulator
OIT41_02120	COG0673	inositol 2-dehydrogenase activity
OIT41_02135	COG0673	inositol 2-dehydrogenase activity
OIT41_02145	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
OIT41_02180	COG0564	pseudouridine synthase activity
OIT41_02190	COG3511	phospholipase C
OIT41_02190	COG3511	phospholipase C
OIT41_02220	COG2364	Membrane
OIT41_02225	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OIT41_02230	COG1201	RNA secondary structure unwinding
OIT41_02255	COG0475	glutathione-regulated potassium exporter activity
OIT41_02255	COG0569	domain protein
OIT41_02305	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OIT41_02310	COG0640	Transcriptional regulator
OIT41_02320	COG1846	Transcriptional regulator
OIT41_02365	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OIT41_02435	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OIT41_02505	COG1846	Transcriptional regulator
OIT41_02565	COG2732	(Barnase) inhibitor
OIT41_02590	COG5001	Diguanylate cyclase
OIT41_02590	COG3300	MHYT domain
OIT41_02640	COG4974	Belongs to the 'phage' integrase family
OIT41_02665	COG1254	Belongs to the acylphosphatase family
OIT41_02680	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OIT41_02695	COG1609	Transcriptional regulator
OIT41_02705	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
OIT41_02710	COG4821	SIS domain
OIT41_02715	COG0363	glucosamine-6-phosphate deaminase activity
OIT41_02730	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OIT41_02735	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OIT41_02750	COG2205	protein histidine kinase activity
OIT41_02755	COG0745	RESPONSE REGULATOR receiver
OIT41_02790	COG0697	spore germination
OIT41_02800	COG1309	transcriptional regulator
OIT41_02805	COG1511	domain protein
OIT41_02820	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
OIT41_02825	COG1940	carbohydrate kinase activity
OIT41_02835	COG4608	Belongs to the ABC transporter superfamily
OIT41_02840	COG0444	Belongs to the ABC transporter superfamily
OIT41_02845	COG0601	transmembrane transport
OIT41_02855	COG2188	Transcriptional regulator
OIT41_02865	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
OIT41_02870	COG0574	Belongs to the PEP-utilizing enzyme family
OIT41_02870	COG3848	Pyruvate phosphate dikinase
OIT41_02900	COG0514	ATP-dependent DNA helicase (RecQ)
OIT41_02905	COG2814	Major facilitator Superfamily
OIT41_02915	COG1505	serine-type exopeptidase activity
OIT41_02935	COG1968	undecaprenyl-diphosphatase activity
OIT41_02945	COG0604	alcohol dehydrogenase
OIT41_02970	COG0656	L-ascorbic acid biosynthetic process
OIT41_02975	COG1609	Transcriptional regulator
OIT41_02985	COG1175	transmembrane transport
OIT41_02990	COG0395	ABC-type sugar transport system, permease component
OIT41_03000	COG0673	inositol 2-dehydrogenase activity
OIT41_03015	COG2801	Transposase and inactivated derivatives
OIT41_03065	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OIT41_03070	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OIT41_03090	COG0588	phosphoglycerate mutase activity
OIT41_03120	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
OIT41_03120	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
OIT41_03125	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
OIT41_03130	COG0215	cysteine-tRNA ligase activity
OIT41_03135	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OIT41_03160	COG0366	Alpha amylase catalytic
OIT41_03165	COG0366	Alpha amylase catalytic
OIT41_03170	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OIT41_03210	COG0277	FAD linked oxidase domain protein
OIT41_03220	COG0402	S-adenosylhomocysteine deaminase activity
OIT41_03235	COG3842	ATPase activity
OIT41_03270	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OIT41_03280	COG0583	DNA-binding transcription factor activity
OIT41_03285	COG2828	Protein conserved in bacteria
OIT41_03290	COG1301	dicarboxylic acid transport
OIT41_03305	COG0531	amino acid
OIT41_03320	COG1621	beta-fructofuranosidase activity
OIT41_03330	COG4608	Belongs to the ABC transporter superfamily
OIT41_03335	COG0444	Belongs to the ABC transporter superfamily
OIT41_03340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OIT41_03345	COG0601	transmembrane transport
OIT41_03350	COG0747	negative chemotaxis
OIT41_03360	COG1621	beta-fructofuranosidase activity
OIT41_03400	COG1309	transcriptional regulator
OIT41_03420	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OIT41_03425	COG0318	PFAM AMP-dependent synthetase and ligase
OIT41_03430	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OIT41_03445	COG0671	phosphoesterase, PA-phosphatase related
OIT41_03460	COG0667	Aldo Keto reductase
OIT41_03475	COG0747	negative chemotaxis
OIT41_03480	COG0601	transmembrane transport
OIT41_03485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OIT41_03510	COG5001	Diguanylate cyclase
OIT41_03530	COG0667	Aldo Keto reductase
OIT41_03535	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OIT41_03545	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OIT41_03555	COG0444	Belongs to the ABC transporter superfamily
OIT41_03580	COG4166	transmembrane transport
OIT41_03585	COG1335	isochorismatase
OIT41_03630	COG0402	S-adenosylhomocysteine deaminase activity
OIT41_03640	COG0154	amidase activity
OIT41_03645	COG3290	protein histidine kinase activity
OIT41_03650	COG4565	transcriptional regulatory protein
OIT41_03660	COG3832	glyoxalase III activity
OIT41_03665	COG0640	Transcriptional regulator
OIT41_03690	COG1177	transmembrane transport
OIT41_03695	COG3842	ATPase activity
OIT41_03735	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OIT41_03740	COG4786	Flagellar basal body rod
OIT41_03740	COG1256	bacterial-type flagellum assembly
OIT41_03750	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OIT41_03770	COG1815	bacterial-type flagellum-dependent cell motility
OIT41_03780	COG1677	Flagellar hook-basal body complex protein FliE
OIT41_03785	COG1766	The M ring may be actively involved in energy transduction
OIT41_03790	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OIT41_03800	COG1157	protein secretion by the type III secretion system
OIT41_03820	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
OIT41_03845	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OIT41_03850	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OIT41_03855	COG0531	amino acid
OIT41_03860	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OIT41_03870	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OIT41_03890	COG0671	phosphoesterase, PA-phosphatase related
OIT41_03905	COG5002	protein histidine kinase activity
OIT41_03930	COG3842	ATPase activity
OIT41_03945	COG0390	transport system, permease component
OIT41_03955	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
OIT41_03960	COG1360	Flagellar Motor Protein
OIT41_03970	COG3585	molybdate ion transport
OIT41_04000	COG1338	Plays a role in the flagellum-specific transport system
OIT41_04005	COG1987	bacterial-type flagellum assembly
OIT41_04015	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OIT41_04020	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OIT41_04030	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
OIT41_04045	COG0477	Major facilitator Superfamily
OIT41_04055	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OIT41_04055	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OIT41_04060	COG0404	The glycine cleavage system catalyzes the degradation of glycine
OIT41_04065	COG0509	glycine decarboxylation via glycine cleavage system
OIT41_04070	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OIT41_04125	COG0459	protein refolding
OIT41_04130	COG0328	RNA-DNA hybrid ribonuclease activity
OIT41_04140	COG2205	protein histidine kinase activity
OIT41_04145	COG0745	RESPONSE REGULATOR receiver
OIT41_04155	COG0583	DNA-binding transcription factor activity
OIT41_04180	COG1278	Cold shock
OIT41_04190	COG2814	Major facilitator Superfamily
OIT41_04205	COG0739	heme binding
OIT41_04240	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OIT41_04255	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OIT41_04260	COG1126	abc transporter atp-binding protein
OIT41_04265	COG0765	amino acid transport
OIT41_04270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OIT41_04285	COG0488	(ABC) transporter
OIT41_04290	COG1132	(ABC) transporter
OIT41_04305	COG0494	nUDIX hydrolase
OIT41_04350	COG0483	inositol monophosphate 1-phosphatase activity
OIT41_04360	COG0045	succinate-CoA ligase (ADP-forming) activity
OIT41_04370	COG1942	4-Oxalocrotonate Tautomerase
OIT41_04385	COG3962	Belongs to the TPP enzyme family
OIT41_04400	COG0673	inositol 2-dehydrogenase activity
OIT41_04405	COG1082	Xylose isomerase domain protein TIM barrel
OIT41_04415	COG0659	secondary active sulfate transmembrane transporter activity
OIT41_04435	COG1609	Transcriptional regulator
OIT41_04445	COG1172	Belongs to the binding-protein-dependent transport system permease family
OIT41_04455	COG0673	inositol 2-dehydrogenase activity
OIT41_04460	COG0673	inositol 2-dehydrogenase activity
OIT41_04465	COG0673	inositol 2-dehydrogenase activity
OIT41_04475	COG0673	inositol 2-dehydrogenase activity
OIT41_04480	COG3718	enzyme involved in inositol metabolism
OIT41_04485	COG2188	Transcriptional regulator
OIT41_04500	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
OIT41_04520	COG0477	Major facilitator Superfamily
OIT41_04530	COG4176	ABC-type proline glycine betaine transport system permease component
OIT41_04535	COG0517	IMP dehydrogenase activity
OIT41_04535	COG4175	Glycine betaine
OIT41_04540	COG1012	belongs to the aldehyde dehydrogenase family
OIT41_04575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIT41_04595	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OIT41_04620	COG1760	l-serine dehydratase
OIT41_04645	COG0726	polysaccharide deacetylase
OIT41_04675	COG1396	sequence-specific DNA binding
OIT41_04705	COG0028	Belongs to the TPP enzyme family
OIT41_04715	COG0477	Major facilitator Superfamily
OIT41_04735	COG3142	Participates in the control of copper homeostasis
OIT41_04745	COG1401	restriction endodeoxyribonuclease activity
OIT41_04765	COG0463	Glycosyl transferase, family 2
OIT41_04790	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OIT41_04795	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OIT41_04815	COG1902	pentaerythritol trinitrate reductase activity
OIT41_04820	COG0477	Major facilitator Superfamily
OIT41_04835	COG2188	Transcriptional regulator
OIT41_04850	COG2183	response to ionizing radiation
OIT41_04855	COG3300	MHYT domain
OIT41_04855	COG5001	Diguanylate cyclase
OIT41_04875	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OIT41_04890	COG0640	Transcriptional regulator
OIT41_04925	COG1309	transcriptional regulator
OIT41_04940	COG0477	Major facilitator Superfamily
OIT41_04985	COG1396	sequence-specific DNA binding
OIT41_05000	COG4565	transcriptional regulatory protein
OIT41_05005	COG1116	anion transmembrane transporter activity
OIT41_05025	COG0667	Aldo Keto reductase
OIT41_05045	COG3547	Transposase (IS116 IS110 IS902 family)
OIT41_05155	COG3547	Transposase (IS116 IS110 IS902 family)
OIT41_05185	COG4221	oxidoreductase activity
OIT41_05200	COG1131	(ABC) transporter
OIT41_05225	COG1116	anion transmembrane transporter activity
OIT41_05255	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OIT41_05260	COG0438	transferase activity, transferring glycosyl groups
OIT41_05275	COG2268	Band 7 protein
OIT41_05280	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIT41_05285	COG2814	Major facilitator Superfamily
OIT41_05300	COG0179	Fumarylacetoacetate (FAA) hydrolase
OIT41_05345	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
OIT41_05355	COG0138	bifunctional purine biosynthesis protein purh
OIT41_05370	COG2838	Isocitrate dehydrogenase
OIT41_05410	COG0673	inositol 2-dehydrogenase activity
OIT41_05415	COG0577	efflux transmembrane transporter activity
OIT41_05415	COG1136	(ABC) transporter
OIT41_05420	COG1136	(ABC) transporter
OIT41_05420	COG0577	efflux transmembrane transporter activity
OIT41_05425	COG4213	ABC transporter substrate-binding protein
OIT41_05465	COG1131	(ABC) transporter
OIT41_05480	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OIT41_05485	COG0531	amino acid
OIT41_05510	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OIT41_05515	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OIT41_05520	COG4585	Histidine kinase
OIT41_05525	COG2197	response regulator
OIT41_05535	COG1131	(ABC) transporter
OIT41_05560	COG0180	Tryptophanyl-tRNA synthetase
OIT41_05580	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OIT41_05595	COG2009	succinate dehydrogenase
OIT41_05605	COG1473	amidohydrolase
OIT41_05605	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
OIT41_05610	COG1846	Transcriptional regulator
OIT41_05615	COG1764	response to oxidative stress
OIT41_05620	COG2130	NADP-dependent
OIT41_05625	COG1744	ABC transporter substrate-binding protein PnrA-like
OIT41_05630	COG3845	ABC transporter
OIT41_05635	COG4603	Belongs to the binding-protein-dependent transport system permease family
OIT41_05640	COG1079	Belongs to the binding-protein-dependent transport system permease family
OIT41_05660	COG0586	Pfam SNARE associated Golgi protein
OIT41_05665	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OIT41_05670	COG3956	TIGRFAM MazG family protein
OIT41_05675	COG0148	phosphopyruvate hydratase activity
OIT41_05700	COG1252	NADH dehydrogenase
OIT41_05730	COG0411	ABC transporter
OIT41_05745	COG0183	Belongs to the thiolase family
OIT41_05750	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
OIT41_05760	COG2017	converts alpha-aldose to the beta-anomer
OIT41_05770	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OIT41_05775	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OIT41_05785	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OIT41_05795	COG1331	Highly conserved protein containing a thioredoxin domain
OIT41_05805	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OIT41_05810	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
OIT41_05850	COG0114	fumarate hydratase activity
OIT41_05855	COG0288	reversible hydration of carbon dioxide
OIT41_05865	COG1494	fructose-1,6-bisphosphatase
OIT41_05880	COG1482	cell wall glycoprotein biosynthetic process
OIT41_05885	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
OIT41_05935	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
OIT41_05945	COG1376	ErfK ybiS ycfS ynhG family protein
OIT41_05990	COG0714	Associated with various cellular activities
OIT41_05995	COG0084	hydrolase, TatD family'
OIT41_06000	COG3583	domain protein
OIT41_06005	COG2801	Transposase and inactivated derivatives
OIT41_06015	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OIT41_06020	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OIT41_06025	COG0488	(ABC) transporter
OIT41_06030	COG1309	transcriptional regulator
OIT41_06040	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OIT41_06050	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OIT41_06055	COG0193	aminoacyl-tRNA hydrolase activity
OIT41_06075	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OIT41_06085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OIT41_06100	COG3979	chitinase
OIT41_06110	COG1215	transferase activity, transferring glycosyl groups
OIT41_06150	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OIT41_06200	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
OIT41_06205	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIT41_06220	COG2814	Major facilitator Superfamily
OIT41_06235	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIT41_06235	COG2146	nitrite reductase [NAD(P)H] activity
OIT41_06245	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OIT41_06280	COG0243	molybdopterin cofactor binding
OIT41_06285	COG2223	nitrite transmembrane transporter activity
OIT41_06290	COG0477	Major facilitator Superfamily
OIT41_06295	COG4770	biotin carboxylase activity
OIT41_06300	COG0424	maF-like protein
OIT41_06305	COG2409	Drug exporters of the RND superfamily
OIT41_06310	COG1309	transcriptional regulator
OIT41_06315	COG0393	Putative heavy-metal-binding
OIT41_06320	COG1823	symporter activity
OIT41_06335	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OIT41_06340	COG1028	Short-chain dehydrogenase reductase Sdr
OIT41_06370	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OIT41_06375	COG0483	inositol monophosphate 1-phosphatase activity
OIT41_06380	COG0456	acetyltransferase
OIT41_06385	COG0251	oxidation-reduction process
OIT41_06390	COG4565	transcriptional regulatory protein
OIT41_06395	COG3290	protein histidine kinase activity
OIT41_06400	COG2851	Citrate transporter
OIT41_06405	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OIT41_06410	COG0154	amidase activity
OIT41_06415	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OIT41_06425	COG1609	Transcriptional regulator
OIT41_06435	COG1175	transmembrane transport
OIT41_06440	COG0395	ABC-type sugar transport system, permease component
OIT41_06460	COG1063	alcohol dehydrogenase
OIT41_06465	COG0156	8-amino-7-oxononanoate synthase activity
OIT41_06470	COG1486	melibiose metabolic process
OIT41_06485	COG1228	amidohydrolase
OIT41_06490	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OIT41_06495	COG1940	carbohydrate kinase activity
OIT41_06515	COG0588	phosphoglycerate mutase activity
OIT41_06530	COG2873	o-acetylhomoserine
OIT41_06535	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OIT41_06565	COG0423	glycine-tRNA ligase activity
OIT41_06585	COG1131	(ABC) transporter
OIT41_06590	COG0842	Transport permease protein
OIT41_06595	COG4585	Histidine kinase
OIT41_06600	COG2197	response regulator
OIT41_06615	COG0358	DNA primase activity
OIT41_06625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIT41_06655	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OIT41_06665	COG0297	glycogen (starch) synthase activity
OIT41_06695	COG3118	belongs to the thioredoxin family
OIT41_06705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OIT41_06740	COG2814	Major facilitator Superfamily
OIT41_06750	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OIT41_06755	COG3263	regulation of cellular component size
OIT41_06785	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OIT41_06795	COG0484	heat shock protein binding
OIT41_06800	COG0071	Belongs to the small heat shock protein (HSP20) family
OIT41_06825	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OIT41_06870	COG0657	acetylesterase activity
OIT41_06875	COG1960	acyl-CoA dehydrogenase activity
OIT41_06885	COG0052	Belongs to the universal ribosomal protein uS2 family
OIT41_06890	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OIT41_06895	COG0528	UMP kinase activity
OIT41_06900	COG0233	cytoplasmic translational termination
OIT41_06905	COG0575	Belongs to the CDS family
OIT41_06930	COG1522	sequence-specific DNA binding
OIT41_06940	COG0022	dehydrogenase e1 component
OIT41_06945	COG0508	dehydrogenase complex catalyzes the overall conversion of
OIT41_06960	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OIT41_06970	COG1960	acyl-CoA dehydrogenase activity
OIT41_07000	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
OIT41_07005	COG0750	zinc metalloprotease
OIT41_07015	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OIT41_07025	COG1309	transcriptional regulator
OIT41_07035	COG1131	(ABC) transporter
OIT41_07040	COG0442	prolyl-tRNA aminoacylation
OIT41_07065	COG0779	Required for maturation of 30S ribosomal subunits
OIT41_07070	COG0195	Participates in both transcription termination and antitermination
OIT41_07080	COG0481	GTPase activity
OIT41_07080	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OIT41_07085	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OIT41_07090	COG0590	tRNA wobble adenosine to inosine editing
OIT41_07095	COG0436	Aminotransferase
OIT41_07100	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OIT41_07120	COG3483	tryptophan 2,3-dioxygenase activity
OIT41_07125	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OIT41_07130	COG1185	polyribonucleotide nucleotidyltransferase activity
OIT41_07135	COG0612	Peptidase, M16
OIT41_07160	COG0745	RESPONSE REGULATOR receiver
OIT41_07180	COG0315	cyclic pyranopterin monophosphate synthase activity
OIT41_07185	COG0521	Mo-molybdopterin cofactor biosynthetic process
OIT41_07195	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
OIT41_07220	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OIT41_07225	COG1674	ftsk spoiiie
OIT41_07235	COG1546	Belongs to the CinA family
OIT41_07235	COG1058	Belongs to the CinA family
OIT41_07240	COG1396	sequence-specific DNA binding
OIT41_07255	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OIT41_07260	COG2137	regulation of response to DNA damage stimulus
OIT41_07270	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OIT41_07275	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OIT41_07280	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OIT41_07285	COG2813	Specifically methylates the guanine in position
OIT41_07290	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OIT41_07300	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OIT41_07310	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OIT41_07315	COG0131	Imidazoleglycerol-phosphate dehydratase
OIT41_07320	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OIT41_07330	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OIT41_07350	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OIT41_07355	COG0291	Belongs to the bacterial ribosomal protein bL35 family
OIT41_07360	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OIT41_07365	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OIT41_07375	COG2814	Major facilitator Superfamily
OIT41_07390	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
OIT41_07400	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OIT41_07405	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OIT41_07405	COG0072	phenylalanine-tRNA ligase activity
OIT41_07435	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OIT41_07440	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OIT41_07445	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
OIT41_07450	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OIT41_07455	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OIT41_07460	COG1438	arginine binding
OIT41_07465	COG0137	argininosuccinate synthase activity
OIT41_07470	COG0165	Argininosuccinate lyase
OIT41_07485	COG2094	Belongs to the DNA glycosylase MPG family
OIT41_07500	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OIT41_07505	COG2801	Transposase and inactivated derivatives
OIT41_07535	COG0647	UMP catabolic process
OIT41_07550	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OIT41_07555	COG0497	DNA recombination
OIT41_07560	COG0504	CTP synthase activity
OIT41_07565	COG0494	nUDIX hydrolase
OIT41_07585	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
OIT41_07590	COG2079	MmgE PrpD family protein
OIT41_07600	COG4565	transcriptional regulatory protein
OIT41_07605	COG3290	protein histidine kinase activity
OIT41_07610	COG1301	dicarboxylic acid transport
OIT41_07620	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OIT41_07625	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OIT41_07635	COG0287	Prephenate dehydrogenase
OIT41_07640	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
OIT41_07650	COG1160	GTP binding
OIT41_07660	COG2824	Alkylphosphonate utilization operon protein PhnA
OIT41_07670	COG2814	Major facilitator Superfamily
OIT41_07675	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OIT41_07680	COG0509	glycine decarboxylation via glycine cleavage system
OIT41_07685	COG1716	ATPase activity
OIT41_07705	COG1192	Involved in chromosome partitioning
OIT41_07710	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
OIT41_07720	COG1940	carbohydrate kinase activity
OIT41_07740	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
OIT41_07745	COG0515	serine threonine protein kinase
OIT41_07745	COG2815	serine threonine protein kinase
OIT41_07750	COG3942	CHAP domain
OIT41_07750	COG1388	LysM domain
OIT41_07760	COG0142	geranyltranstransferase activity
OIT41_07770	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OIT41_07780	COG2001	Belongs to the MraZ family
OIT41_07785	COG0275	rRNA processing
OIT41_07795	COG0768	penicillin binding
OIT41_07800	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OIT41_07810	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OIT41_07815	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OIT41_07825	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OIT41_07830	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OIT41_07835	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OIT41_07840	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OIT41_07850	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OIT41_07855	COG1799	cell septum assembly
OIT41_07870	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OIT41_07880	COG0587	DNA-directed DNA polymerase activity
OIT41_07895	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OIT41_07900	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OIT41_07920	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
OIT41_07925	COG0174	glutamine synthetase
OIT41_07930	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
OIT41_07950	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OIT41_07970	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OIT41_07975	COG0321	lipoyl(octanoyl) transferase activity
OIT41_07985	COG1090	epimerase
OIT41_07990	COG4946	Tricorn protease homolog
OIT41_07990	COG0793	Belongs to the peptidase S41A family
OIT41_07995	COG1764	response to oxidative stress
OIT41_08005	COG0508	dehydrogenase complex catalyzes the overall conversion of
OIT41_08010	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OIT41_08015	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OIT41_08035	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OIT41_08040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIT41_08075	COG1271	oxidase subunit
OIT41_08080	COG1294	oxidase, subunit
OIT41_08085	COG4988	ABC transporter
OIT41_08105	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OIT41_08125	COG1435	thymidine kinase activity
OIT41_08145	COG0756	dUTP diphosphatase activity
OIT41_08170	COG0569	domain protein
OIT41_08175	COG0531	amino acid
OIT41_08180	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OIT41_08185	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OIT41_08190	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OIT41_08205	COG0667	Aldo Keto reductase
OIT41_08220	COG1250	3-hydroxyacyl-CoA dehydrogenase
OIT41_08220	COG1024	Enoyl-CoA hydratase
OIT41_08225	COG0183	Belongs to the thiolase family
OIT41_08255	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OIT41_08290	COG3135	benzoate transporter
OIT41_08300	COG0531	amino acid
OIT41_08340	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OIT41_08360	COG0242	peptide deformylase activity
OIT41_08365	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OIT41_08375	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OIT41_08395	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OIT41_08395	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OIT41_08400	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OIT41_08400	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OIT41_08405	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
OIT41_08410	COG0140	phosphoribosyl-ATP diphosphatase activity
OIT41_08415	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OIT41_08420	COG0107	imidazoleglycerol-phosphate synthase activity
OIT41_08430	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OIT41_08450	COG0134	indole-3-glycerol-phosphate synthase activity
OIT41_08455	COG0133	tryptophan synthase activity
OIT41_08460	COG0159	tryptophan synthase activity
OIT41_08465	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OIT41_08470	COG0069	glutamate synthase activity
OIT41_08470	COG0070	glutamate synthase
OIT41_08470	COG0067	glutamate synthase
OIT41_08570	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
OIT41_08575	COG1396	sequence-specific DNA binding
OIT41_08655	COG3328	transposase activity
OIT41_08750	COG1404	Belongs to the peptidase S8 family
OIT41_08760	COG4249	Peptidase C14 caspase catalytic subunit p20
OIT41_08760	COG2319	Wd-40 repeat
OIT41_08780	COG0656	L-ascorbic acid biosynthetic process
OIT41_08790	COG0673	inositol 2-dehydrogenase activity
OIT41_08795	COG1028	Short-chain dehydrogenase reductase Sdr
OIT41_08815	COG1879	ABC-type sugar transport system periplasmic component
OIT41_08820	COG1172	Belongs to the binding-protein-dependent transport system permease family
OIT41_08825	COG1129	ABC transporter
OIT41_08830	COG1940	carbohydrate kinase activity
OIT41_08850	COG1063	alcohol dehydrogenase
OIT41_08860	COG1175	transmembrane transport
OIT41_08870	COG0673	inositol 2-dehydrogenase activity
OIT41_08875	COG1940	carbohydrate kinase activity
OIT41_08885	COG0667	Aldo Keto reductase
OIT41_08890	COG0667	Aldo Keto reductase
OIT41_08905	COG0071	Belongs to the small heat shock protein (HSP20) family
OIT41_08910	COG0789	Transcriptional regulator
OIT41_08945	COG0515	serine threonine protein kinase
OIT41_08945	COG2815	serine threonine protein kinase
OIT41_08955	COG1846	Transcriptional regulator
OIT41_08980	COG2855	membrane
OIT41_09005	COG3559	Exporter of polyketide antibiotics
OIT41_09010	COG1131	(ABC) transporter
OIT41_09030	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
OIT41_09040	COG0745	RESPONSE REGULATOR receiver
OIT41_09045	COG5002	protein histidine kinase activity
OIT41_09045	COG3850	Histidine kinase
OIT41_09050	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIT41_09050	COG1017	nitric oxide dioxygenase activity
OIT41_09065	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
OIT41_09090	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
OIT41_09095	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
OIT41_09100	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OIT41_09115	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
OIT41_09125	COG1695	Transcriptional regulator
OIT41_09145	COG1937	Protein conserved in bacteria
OIT41_09150	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OIT41_09165	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OIT41_09175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIT41_09190	COG0574	Belongs to the PEP-utilizing enzyme family
OIT41_09190	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OIT41_09225	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
OIT41_09250	COG0574	Belongs to the PEP-utilizing enzyme family
OIT41_09250	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OIT41_09320	COG2217	Heavy metal translocating P-type atpase
OIT41_09360	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
OIT41_09410	COG0531	amino acid
OIT41_09440	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OIT41_09460	COG1396	sequence-specific DNA binding
OIT41_09465	COG0492	ferredoxin-NADP+ reductase activity
OIT41_09470	COG0667	Aldo Keto reductase
OIT41_09505	COG1609	Transcriptional regulator
OIT41_09545	COG1104	cysteine desulfurase activity
OIT41_09570	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OIT41_09585	COG0688	phosphatidylethanolamine metabolic process
OIT41_09645	COG1028	Short-chain dehydrogenase reductase Sdr
OIT41_09650	COG1309	transcriptional regulator
OIT41_09695	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
OIT41_09705	COG0633	Ferredoxin
OIT41_09705	COG0543	2 iron, 2 sulfur cluster binding
OIT41_09710	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OIT41_09715	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
OIT41_09730	COG2801	Transposase and inactivated derivatives
OIT41_09755	COG0789	Transcriptional regulator
OIT41_09780	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OIT41_09785	COG0667	Aldo Keto reductase
OIT41_09795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OIT41_09805	COG2124	cytochrome p450
OIT41_09810	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIT41_09815	COG1668	transmembrane transport
OIT41_09825	COG1131	(ABC) transporter
OIT41_09835	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OIT41_09840	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
OIT41_09860	COG3795	YCII-related domain
OIT41_09865	COG4941	Belongs to the sigma-70 factor family
OIT41_09890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIT41_09935	COG1309	transcriptional regulator
OIT41_09945	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
OIT41_09970	COG4632	Exopolysaccharide biosynthesis protein
OIT41_09970	COG5434	Belongs to the glycosyl hydrolase 28 family
OIT41_09975	COG0598	Magnesium transport protein CorA
OIT41_09985	COG2902	Dehydrogenase
OIT41_09995	COG0318	PFAM AMP-dependent synthetase and ligase
OIT41_10050	COG3387	PFAM Glycoside hydrolase 15-related
OIT41_10060	COG0243	molybdopterin cofactor binding
OIT41_10060	COG3383	formate dehydrogenase (NAD+) activity
OIT41_10065	COG0437	4 iron, 4 sulfur cluster binding
OIT41_10105	COG0651	ATP synthesis coupled electron transport
OIT41_10130	COG1012	belongs to the aldehyde dehydrogenase family
OIT41_10150	COG3226	Transcriptional regulator
OIT41_10160	COG4952	isomerase
OIT41_10165	COG3347	Dehydrogenase
OIT41_10165	COG1028	Short-chain dehydrogenase reductase Sdr
OIT41_10170	COG1070	Carbohydrate kinase
OIT41_10180	COG2814	Major facilitator Superfamily
OIT41_10225	COG1012	belongs to the aldehyde dehydrogenase family
OIT41_10235	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OIT41_10240	COG1024	Enoyl-CoA hydratase
OIT41_10245	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OIT41_10255	COG1396	sequence-specific DNA binding
OIT41_10260	COG0477	Major facilitator Superfamily
OIT41_10270	COG3422	double-strand break repair
OIT41_10280	COG0515	serine threonine protein kinase
OIT41_10310	COG0673	inositol 2-dehydrogenase activity
OIT41_10315	COG1126	abc transporter atp-binding protein
OIT41_10320	COG0765	amino acid transport
OIT41_10335	COG3959	Transketolase, thiamine diphosphate binding domain
OIT41_10390	COG0121	glutamine amidotransferase
OIT41_10395	COG0076	glutamate decarboxylase activity
OIT41_10410	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OIT41_10420	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OIT41_10435	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
OIT41_10440	COG0339	signal peptide processing
OIT41_10455	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
OIT41_10460	COG0217	transcriptional regulatory protein
OIT41_10465	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
OIT41_10470	COG0632	four-way junction helicase activity
OIT41_10475	COG2255	four-way junction helicase activity
OIT41_10485	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OIT41_10490	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OIT41_10495	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OIT41_10505	COG1196	nuclear chromosome segregation
OIT41_10515	COG0124	histidyl-tRNA synthetase
OIT41_10520	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OIT41_10540	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OIT41_10555	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OIT41_10560	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OIT41_10570	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OIT41_10575	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OIT41_10580	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OIT41_10585	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OIT41_10595	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OIT41_10600	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OIT41_10605	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
OIT41_10610	COG0540	Belongs to the ATCase OTCase family
OIT41_10615	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OIT41_10625	COG0505	Belongs to the CarA family
OIT41_10630	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
OIT41_10635	COG0284	orotidine-5'-phosphate decarboxylase activity
OIT41_10640	COG0194	GDP metabolic process
OIT41_10645	COG0194	GDP metabolic process
OIT41_10650	COG1758	RNA polymerase activity
OIT41_10660	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OIT41_10670	COG0438	transferase activity, transferring glycosyl groups
OIT41_10680	COG0656	L-ascorbic acid biosynthetic process
OIT41_10685	COG2390	Transcriptional regulator
OIT41_10690	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OIT41_10695	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OIT41_10700	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OIT41_10705	COG0495	leucyl-tRNA aminoacylation
OIT41_10710	COG1307	EDD domain protein, DegV family
OIT41_10735	COG0268	Binds directly to 16S ribosomal RNA
OIT41_10745	COG0481	GTPase activity
OIT41_10765	COG1420	regulation of RNA biosynthetic process
OIT41_10770	COG0484	heat shock protein binding
OIT41_10775	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OIT41_10790	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OIT41_10800	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OIT41_10805	COG1316	TRANSCRIPTIONal
OIT41_10810	COG3590	peptidase
OIT41_10815	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OIT41_10820	COG1381	Involved in DNA repair and RecF pathway recombination
OIT41_10825	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OIT41_10830	COG2267	carboxylic ester hydrolase activity
OIT41_10845	COG0167	dihydroorotate dehydrogenase activity
OIT41_10865	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OIT41_10870	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OIT41_10880	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OIT41_10885	COG2188	Transcriptional regulator
OIT41_10890	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
OIT41_10895	COG0723	plastoquinol--plastocyanin reductase activity
OIT41_10900	COG2010	Cytochrome c
OIT41_10905	COG1845	cytochrome c oxidase, subunit III
OIT41_10910	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OIT41_10930	COG1316	TRANSCRIPTIONal
OIT41_10935	COG1280	lysine exporter protein (LysE YggA)
OIT41_10945	COG1335	isochorismatase
OIT41_10955	COG0384	phenazine biosynthesis protein PhzF
OIT41_10975	COG4974	Belongs to the 'phage' integrase family
OIT41_11015	COG3424	synthase
OIT41_11020	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OIT41_11030	COG0242	peptide deformylase activity
OIT41_11035	COG4946	Tricorn protease homolog
OIT41_11035	COG1506	peptidase
OIT41_11035	COG0823	Involved in the tonB-independent uptake of proteins
OIT41_11060	COG1216	Glycosyl transferase, family 2
OIT41_11065	COG1574	metal-dependent hydrolase with the TIM-barrel fold
OIT41_11070	COG4581	dead DEAH box helicase
OIT41_11075	COG0805	protein transport
OIT41_11080	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OIT41_11100	COG0545	Peptidyl-prolyl cis-trans isomerase
OIT41_11105	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
OIT41_11110	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
OIT41_11115	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
OIT41_11125	COG4122	O-methyltransferase activity
OIT41_11130	COG1222	aaa ATPase
OIT41_11140	COG0517	IMP dehydrogenase activity
OIT41_11140	COG1994	Peptidase M50
OIT41_11145	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OIT41_11155	COG0215	cysteine-tRNA ligase activity
OIT41_11160	COG1968	undecaprenyl-diphosphatase activity
OIT41_11185	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OIT41_11200	COG1028	Short-chain dehydrogenase reductase Sdr
OIT41_11205	COG0183	Belongs to the thiolase family
OIT41_11220	COG0297	glycogen (starch) synthase activity
OIT41_11225	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
OIT41_11250	COG2855	membrane
OIT41_11265	COG0254	rRNA binding
OIT41_11280	COG1119	ATPase activity
OIT41_11285	COG0560	Phosphoserine phosphatase
OIT41_11285	COG3830	Belongs to the UPF0237 family
OIT41_11290	COG1028	Short-chain dehydrogenase reductase Sdr
OIT41_11295	COG1028	Short-chain dehydrogenase reductase Sdr
OIT41_11325	COG0488	(ABC) transporter
OIT41_11335	COG1268	BioY protein
OIT41_11340	COG1122	ATPase activity
OIT41_11355	COG0318	PFAM AMP-dependent synthetase and ligase
OIT41_11360	COG2151	metal-sulfur cluster biosynthetic enzyme
OIT41_11365	COG0396	ATPase activity
OIT41_11390	COG1131	(ABC) transporter
OIT41_11400	COG1612	heme a metabolic process
OIT41_11405	COG0109	protoheme IX farnesyltransferase activity
OIT41_11415	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OIT41_11420	COG0166	Belongs to the GPI family
OIT41_11435	COG0363	glucosamine-6-phosphate deaminase activity
OIT41_11445	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
OIT41_11450	COG0149	triose-phosphate isomerase activity
OIT41_11455	COG0126	phosphoglycerate kinase activity
OIT41_11460	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OIT41_11465	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OIT41_11470	COG1481	regulation of sporulation
OIT41_11475	COG0391	Required for morphogenesis under gluconeogenic growth conditions
OIT41_11480	COG1660	Displays ATPase and GTPase activities
OIT41_11485	COG0322	excinuclease ABC activity
OIT41_11495	COG0546	phosphoglycolate phosphatase activity
OIT41_11520	COG4106	trans-aconitate 2-methyltransferase activity
OIT41_11545	COG0556	nucleotide-excision repair
OIT41_11550	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OIT41_11550	COG0237	dephospho-CoA kinase activity
OIT41_11555	COG1739	Uncharacterized protein family UPF0029
OIT41_11560	COG0539	negative regulation of cytoplasmic translation
OIT41_11570	COG4552	Acetyltransferase involved in intracellular survival and related
OIT41_11580	COG2050	protein possibly involved in aromatic compounds catabolism
OIT41_11585	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OIT41_11620	COG3483	tryptophan 2,3-dioxygenase activity
OIT41_11650	COG0009	L-threonylcarbamoyladenylate synthase
OIT41_11670	COG1643	Atp-dependent helicase
OIT41_11705	COG1064	alcohol dehydrogenase
OIT41_11710	COG0667	Aldo Keto reductase
OIT41_11725	COG0492	ferredoxin-NADP+ reductase activity
OIT41_11800	COG0412	Dienelactone hydrolase
OIT41_11805	COG1234	tRNA 3'-trailer cleavage
OIT41_11810	COG4804	nuclease activity
OIT41_11835	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OIT41_11840	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OIT41_11845	COG1780	Probably involved in ribonucleotide reductase function
OIT41_11855	COG0583	DNA-binding transcription factor activity
OIT41_11865	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OIT41_11870	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
OIT41_11890	COG1653	transport
OIT41_11905	COG2813	Specifically methylates the guanine in position
OIT41_11935	COG1309	transcriptional regulator
OIT41_11940	COG1028	Short-chain dehydrogenase reductase Sdr
OIT41_11950	COG0477	Major facilitator Superfamily
OIT41_11960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OIT41_11970	COG2957	Belongs to the agmatine deiminase family
OIT41_11975	COG0154	amidase activity
OIT41_11980	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OIT41_12000	COG0444	Belongs to the ABC transporter superfamily
OIT41_12035	COG0587	DNA-directed DNA polymerase activity
OIT41_12045	COG0673	inositol 2-dehydrogenase activity
OIT41_12050	COG1609	Transcriptional regulator
OIT41_12060	COG1609	Transcriptional regulator
OIT41_12070	COG0799	negative regulation of ribosome biogenesis
OIT41_12080	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OIT41_12090	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OIT41_12095	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OIT41_12100	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OIT41_12105	COG0211	Belongs to the bacterial ribosomal protein bL27 family
OIT41_12110	COG0261	This protein binds to 23S rRNA in the presence of protein L20
OIT41_12115	COG0351	phosphomethylpyrimidine kinase
OIT41_12115	COG0352	thiamine-phosphate diphosphorylase activity
OIT41_12115	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OIT41_12120	COG1530	ribonuclease E activity
OIT41_12130	COG0105	UTP biosynthetic process
OIT41_12140	COG0285	dihydrofolate synthase activity
OIT41_12145	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OIT41_12160	COG3189	MarR family transcriptional regulator
OIT41_12165	COG0525	valine-tRNA ligase activity
OIT41_12170	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OIT41_12175	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OIT41_12180	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OIT41_12185	COG0740	serine-type endopeptidase activity
OIT41_12190	COG0740	serine-type endopeptidase activity
OIT41_12195	COG0544	peptidyl-prolyl cis-trans isomerase activity
OIT41_12235	COG0668	transmembrane transport
OIT41_12250	COG1946	Acyl-CoA thioesterase
OIT41_12265	COG0629	single-stranded DNA binding
OIT41_12315	COG0242	peptide deformylase activity
OIT41_12345	COG3022	response to hydroperoxide
OIT41_12355	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OIT41_12360	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OIT41_12370	COG1045	serine acetyltransferase
OIT41_12375	COG0300	oxidoreductase activity
OIT41_12380	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OIT41_12390	COG1063	alcohol dehydrogenase
OIT41_12395	COG1028	Short-chain dehydrogenase reductase Sdr
OIT41_12410	COG0477	Major facilitator Superfamily
OIT41_12445	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
OIT41_12460	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OIT41_12465	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OIT41_12480	COG4974	Belongs to the 'phage' integrase family
OIT41_12495	COG0792	nuclease activity
OIT41_12505	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OIT41_12515	COG0681	Belongs to the peptidase S26 family
OIT41_12520	COG0335	large ribosomal subunit rRNA binding
OIT41_12525	COG0336	Belongs to the RNA methyltransferase TrmD family
OIT41_12530	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OIT41_12535	COG1837	Belongs to the UPF0109 family
OIT41_12540	COG0228	four-way junction DNA binding
OIT41_12550	COG2514	catechol 2,3-dioxygenase activity
OIT41_12575	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OIT41_12590	COG2814	Major facilitator Superfamily
OIT41_12605	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OIT41_12610	COG0571	ribonuclease III activity
OIT41_12615	COG0333	Belongs to the bacterial ribosomal protein bL32 family
OIT41_12625	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OIT41_12640	COG0742	ribosomal rna small subunit methyltransferase
OIT41_12665	COG1181	Belongs to the D-alanine--D-alanine ligase family
OIT41_12670	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
OIT41_12680	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OIT41_12685	COG0066	3-isopropylmalate dehydratase activity
OIT41_12690	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OIT41_12695	COG1414	Transcriptional regulator
OIT41_12720	COG1011	Hydrolase
OIT41_12725	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OIT41_12730	COG0179	Fumarylacetoacetate (FAA) hydrolase
OIT41_12735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIT41_12745	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OIT41_12750	COG0473	3-isopropylmalate dehydrogenase activity
OIT41_12760	COG0577	efflux transmembrane transporter activity
OIT41_12760	COG1136	(ABC) transporter
OIT41_12770	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OIT41_12775	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OIT41_12780	COG0440	acetolactate synthase activity
OIT41_12790	COG0129	dihydroxy-acid dehydratase activity
OIT41_12825	COG0747	negative chemotaxis
OIT41_12830	COG0579	oxidoreductase
OIT41_12835	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OIT41_12840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIT41_12850	COG1305	Transglutaminase-like
OIT41_12865	COG0179	Fumarylacetoacetate (FAA) hydrolase
OIT41_12875	COG1104	cysteine desulfurase activity
OIT41_12885	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
OIT41_12890	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OIT41_12905	COG1113	amino acid transport
OIT41_12915	COG0022	dehydrogenase e1 component
OIT41_12920	COG0508	dehydrogenase complex catalyzes the overall conversion of
OIT41_13000	COG1414	Transcriptional regulator
OIT41_13010	COG0419	ATPase involved in DNA repair
OIT41_13015	COG0420	3'-5' exonuclease activity
OIT41_13020	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OIT41_13025	COG2149	membrane
OIT41_13055	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OIT41_13070	COG0586	Pfam SNARE associated Golgi protein
OIT41_13075	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OIT41_13080	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OIT41_13085	COG1234	tRNA 3'-trailer cleavage
OIT41_13090	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OIT41_13100	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
OIT41_13110	COG1335	isochorismatase
OIT41_13125	COG0363	glucosamine-6-phosphate deaminase activity
OIT41_13140	COG1902	pentaerythritol trinitrate reductase activity
OIT41_13170	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
OIT41_13175	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
OIT41_13190	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
OIT41_13195	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
OIT41_13205	COG0355	proton-transporting ATP synthase activity, rotational mechanism
OIT41_13210	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OIT41_13215	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OIT41_13220	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OIT41_13225	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OIT41_13230	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OIT41_13235	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OIT41_13240	COG0356	it plays a direct role in the translocation of protons across the membrane
OIT41_13255	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OIT41_13275	COG2890	protein-(glutamine-N5) methyltransferase activity
OIT41_13280	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OIT41_13290	COG0083	homoserine kinase activity
OIT41_13295	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OIT41_13300	COG0460	homoserine dehydrogenase
OIT41_13305	COG0019	diaminopimelate decarboxylase activity
OIT41_13310	COG0018	arginyl-trna synthetase
OIT41_13325	COG0633	Ferredoxin
OIT41_13325	COG0543	2 iron, 2 sulfur cluster binding
OIT41_13360	COG1643	Atp-dependent helicase
OIT41_13370	COG1064	alcohol dehydrogenase
OIT41_13380	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OIT41_13395	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OIT41_13400	COG1121	(ABC) transporter
OIT41_13415	COG1253	flavin adenine dinucleotide binding
OIT41_13420	COG0567	Dehydrogenase, E1 component
OIT41_13420	COG0508	dehydrogenase complex catalyzes the overall conversion of
OIT41_13445	COG1595	DNA-templated transcription, initiation
OIT41_13455	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OIT41_13465	COG0483	inositol monophosphate 1-phosphatase activity
OIT41_13470	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OIT41_13505	COG2801	Transposase and inactivated derivatives
OIT41_13520	COG1028	Short-chain dehydrogenase reductase Sdr
OIT41_13530	COG1960	acyl-CoA dehydrogenase activity
OIT41_13540	COG0477	Major facilitator Superfamily
OIT41_13555	COG0477	Major facilitator Superfamily
OIT41_13575	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OIT41_13585	COG2177	Part of the ABC transporter FtsEX involved in
OIT41_13590	COG2884	Cell division ATP-binding protein ftsE
OIT41_13595	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
OIT41_13640	COG1088	dTDP-glucose 4,6-dehydratase activity
OIT41_13650	COG1216	Glycosyl transferase, family 2
OIT41_13665	COG1215	transferase activity, transferring glycosyl groups
OIT41_13685	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
OIT41_13695	COG0656	L-ascorbic acid biosynthetic process
OIT41_13710	COG1216	Glycosyl transferase, family 2
OIT41_13740	COG2902	Dehydrogenase
OIT41_13870	COG0653	protein targeting
OIT41_13875	COG3214	Protein conserved in bacteria
OIT41_13880	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
OIT41_13885	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OIT41_13890	COG5401	PFAM Sporulation and spore germination
OIT41_13895	COG5002	protein histidine kinase activity
OIT41_13920	COG0714	Associated with various cellular activities
OIT41_13955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OIT41_13960	COG0601	transmembrane transport
OIT41_13970	COG0482	sulfurtransferase activity
OIT41_13995	COG0484	heat shock protein binding
OIT41_14000	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OIT41_14025	COG3265	gluconokinase activity
OIT41_14035	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
OIT41_14040	COG2086	electron transfer activity
OIT41_14045	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OIT41_14055	COG1842	Phage shock protein A
OIT41_14060	COG1960	acyl-CoA dehydrogenase activity
OIT41_14070	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
OIT41_14075	COG2086	electron transfer activity
OIT41_14100	COG2801	Transposase and inactivated derivatives
OIT41_14105	COG1615	UPF0182 protein
OIT41_14110	COG3480	Lon protease (S16) C-terminal proteolytic domain
OIT41_14130	COG2816	NAD+ diphosphatase activity
OIT41_14140	COG0210	DNA helicase
OIT41_14160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OIT41_14165	COG0765	amino acid transport
OIT41_14170	COG1126	abc transporter atp-binding protein
OIT41_14175	COG1472	Belongs to the glycosyl hydrolase 3 family
OIT41_14180	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OIT41_14185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIT41_14190	COG0113	porphobilinogen synthase activity
OIT41_14200	COG0181	hydroxymethylbilane synthase activity
OIT41_14205	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
OIT41_14210	COG3253	May function as heme-dependent peroxidase
OIT41_14220	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OIT41_14225	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
OIT41_14240	COG1309	transcriptional regulator
OIT41_14255	COG2154	pterin-4-alpha-carbinolamine dehydratase
OIT41_14260	COG2022	thiamine diphosphate biosynthetic process
OIT41_14270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OIT41_14270	COG2022	thiamine diphosphate biosynthetic process
OIT41_14275	COG0352	thiamine-phosphate diphosphorylase activity
OIT41_14285	COG0513	Belongs to the DEAD box helicase family
OIT41_14290	COG2189	Belongs to the N(4) N(6)-methyltransferase family
OIT41_14295	COG0613	PHP domain protein
OIT41_14300	COG0006	proline dipeptidase activity
OIT41_14310	COG2239	Acts as a magnesium transporter
OIT41_14325	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OIT41_14335	COG1595	DNA-templated transcription, initiation
OIT41_14365	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OIT41_14370	COG2171	N-acyltransferase activity
OIT41_14385	COG3226	Transcriptional regulator
OIT41_14390	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OIT41_14435	COG1217	gtp-binding protein TYPA
OIT41_14445	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OIT41_14450	COG0601	transmembrane transport
OIT41_14455	COG4166	transmembrane transport
OIT41_14475	COG0601	transmembrane transport
OIT41_14480	COG4166	transmembrane transport
OIT41_14500	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OIT41_14515	COG3549	Plasmid maintenance system killer
OIT41_14570	COG0012	GTP binding
OIT41_14580	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OIT41_14590	COG1570	exodeoxyribonuclease VII activity
OIT41_14595	COG1722	exodeoxyribonuclease VII activity
OIT41_14600	COG2326	polyphosphate kinase activity
OIT41_14620	COG1174	glycine betaine transport
OIT41_14640	COG2971	BadF BadG BcrA BcrD
OIT41_14645	COG0583	DNA-binding transcription factor activity
OIT41_14650	COG2814	Major facilitator Superfamily
OIT41_14655	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OIT41_14660	COG0626	cystathionine gamma-synthase activity
OIT41_14695	COG0598	Magnesium transport protein CorA
OIT41_14720	COG2329	Antibiotic biosynthesis monooxygenase
OIT41_14730	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OIT41_14735	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OIT41_14740	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OIT41_14765	COG4948	Mandelate Racemase Muconate Lactonizing
OIT41_14775	COG0246	Mannitol dehydrogenase
OIT41_14780	COG1904	glucuronate isomerase
OIT41_14785	COG1609	Transcriptional regulator
OIT41_14790	COG0673	inositol 2-dehydrogenase activity
OIT41_14830	COG3265	gluconokinase activity
OIT41_14865	COG1012	belongs to the aldehyde dehydrogenase family
OIT41_14870	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OIT41_14910	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OIT41_14915	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OIT41_14935	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OIT41_14935	COG0519	Catalyzes the synthesis of GMP from XMP
OIT41_14955	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OIT41_14960	COG0516	GMP reductase activity
OIT41_14970	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
OIT41_14970	COG2755	lipolytic protein G-D-S-L family
OIT41_14975	COG0459	protein refolding
OIT41_14980	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OIT41_14995	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OIT41_15000	COG0257	Belongs to the bacterial ribosomal protein bL36 family
OIT41_15010	COG2732	(Barnase) inhibitor
OIT41_15035	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OIT41_15040	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIT41_15045	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OIT41_15070	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
OIT41_15075	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OIT41_15090	COG0802	atpase or kinase
OIT41_15095	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OIT41_15110	COG0438	transferase activity, transferring glycosyl groups
OIT41_15115	COG2759	Belongs to the formate--tetrahydrofolate ligase family
OIT41_15125	COG3328	transposase activity
OIT41_15140	COG0667	Aldo Keto reductase
OIT41_15165	COG0736	holo-[acyl-carrier-protein] synthase activity
OIT41_15175	COG1072	(Pantothenic acid kinase))
OIT41_15180	COG1876	peptidase activity
OIT41_15185	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OIT41_15195	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OIT41_15195	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OIT41_15200	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OIT41_15205	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OIT41_15240	COG0455	bacterial-type flagellum organization
OIT41_15260	COG0101	tRNA pseudouridine synthase activity
OIT41_15265	COG0203	ribosomal protein L17
OIT41_15270	COG0202	RNA polymerase activity
OIT41_15275	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OIT41_15280	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OIT41_15285	COG0257	Belongs to the bacterial ribosomal protein bL36 family
OIT41_15290	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OIT41_15295	COG3191	aminopeptidase activity
OIT41_15305	COG1175	transmembrane transport
OIT41_15320	COG0024	Methionine aminopeptidase
OIT41_15325	COG0563	adenylate kinase activity
OIT41_15335	COG0200	Binds to the 23S rRNA
OIT41_15340	COG1841	ribosomal large subunit assembly
OIT41_15345	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
OIT41_15355	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OIT41_15360	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OIT41_15365	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OIT41_15370	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OIT41_15375	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OIT41_15380	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OIT41_15390	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OIT41_15395	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OIT41_15400	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
OIT41_15405	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OIT41_15410	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OIT41_15415	COG0089	rRNA binding
OIT41_15420	COG0088	Forms part of the polypeptide exit tunnel
OIT41_15425	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OIT41_15430	COG0051	transcription antitermination factor activity, RNA binding
OIT41_15435	COG2723	6-phospho-beta-galactosidase activity
OIT41_15450	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OIT41_15455	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OIT41_15460	COG0049	tRNA binding
OIT41_15465	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OIT41_15470	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OIT41_15475	COG0085	RNA polymerase activity
OIT41_15480	COG0183	Belongs to the thiolase family
OIT41_15485	COG0442	prolyl-tRNA aminoacylation
OIT41_15490	COG0222	ribosome binding
OIT41_15495	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OIT41_15510	COG0081	regulation of translation
OIT41_15515	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OIT41_15535	COG0436	Aminotransferase
OIT41_15540	COG2197	response regulator
OIT41_15590	COG0354	folic acid binding
OIT41_15600	COG3485	protocatechuate 3,4-dioxygenase
OIT41_15610	COG0745	RESPONSE REGULATOR receiver
OIT41_15615	COG0456	acetyltransferase
OIT41_15620	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
OIT41_15630	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OIT41_15635	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OIT41_15645	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OIT41_15660	COG0812	UDP-N-acetylmuramate dehydrogenase activity
OIT41_15665	COG2030	dehydratase
OIT41_15670	COG2030	dehydratase
OIT41_15690	COG4989	oxidoreductase activity
OIT41_15695	COG0366	Alpha amylase catalytic
OIT41_15700	COG1940	carbohydrate kinase activity
OIT41_15715	COG1388	LysM domain
OIT41_15715	COG3942	CHAP domain
OIT41_15730	COG4974	Belongs to the 'phage' integrase family
OIT41_15750	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OIT41_15775	COG0791	NLP P60 protein
OIT41_15775	COG3103	Sh3 type 3 domain protein
OIT41_15775	COG1388	LysM domain
OIT41_15840	COG0318	PFAM AMP-dependent synthetase and ligase
OIT41_15850	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OIT41_15875	COG1666	GTP binding
OIT41_15885	COG0501	Belongs to the peptidase M48B family
OIT41_15890	COG0531	amino acid
OIT41_15910	COG0531	amino acid
OIT41_15955	COG1012	belongs to the aldehyde dehydrogenase family
OIT41_15960	COG2508	Transcriptional regulator
OIT41_15960	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
OIT41_15965	COG2807	transmembrane transport
OIT41_15970	COG2186	Transcriptional regulator
OIT41_15975	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OIT41_15975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIT41_15985	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OIT41_15985	COG1648	precorrin-2 dehydrogenase activity
OIT41_15990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIT41_16000	COG1116	anion transmembrane transporter activity
OIT41_16020	COG0175	sulfate reduction
OIT41_16025	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIT41_16035	COG2860	membrane
OIT41_16050	COG0142	geranyltranstransferase activity
OIT41_16055	COG0644	oxidoreductase
OIT41_16060	COG2226	methyltransferase
OIT41_16065	COG1169	isochorismate synthase
OIT41_16075	COG0765	amino acid transport
OIT41_16085	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
OIT41_16095	COG4948	Mandelate Racemase Muconate Lactonizing
OIT41_16100	COG1609	Transcriptional regulator
OIT41_16110	COG0395	ABC-type sugar transport system, permease component
OIT41_16115	COG1175	transmembrane transport
OIT41_16150	COG0701	Predicted permease
OIT41_16200	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OIT41_16210	COG0640	Transcriptional regulator
OIT41_16215	COG0702	epimerase
OIT41_16225	COG3979	chitinase
OIT41_16235	COG0640	Transcriptional regulator
OIT41_16260	COG1309	transcriptional regulator
OIT41_16265	COG0562	UDP-galactopyranose mutase
OIT41_16290	COG2197	response regulator
OIT41_16335	COG0508	dehydrogenase complex catalyzes the overall conversion of
OIT41_16340	COG0022	dehydrogenase e1 component
OIT41_16355	COG0489	protein tyrosine kinase activity
OIT41_16360	COG3307	-O-antigen
OIT41_16380	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
OIT41_16385	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OIT41_16395	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OIT41_16410	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OIT41_16415	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OIT41_16430	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OIT41_16435	COG1316	TRANSCRIPTIONal
OIT41_16445	COG0640	Transcriptional regulator
OIT41_16505	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIT41_16510	COG2151	metal-sulfur cluster biosynthetic enzyme
OIT41_16515	COG3396	Phenylacetate-CoA oxygenase
OIT41_16520	COG3460	Phenylacetate-CoA oxygenase
OIT41_16525	COG3396	Phenylacetate-CoA oxygenase
OIT41_16535	COG5002	protein histidine kinase activity
OIT41_16540	COG0745	RESPONSE REGULATOR receiver
OIT41_16565	COG1192	Involved in chromosome partitioning
OIT41_16595	COG0574	Belongs to the PEP-utilizing enzyme family
OIT41_16595	COG3848	Pyruvate phosphate dikinase
OIT41_16610	COG1316	TRANSCRIPTIONal
OIT41_16635	COG5002	protein histidine kinase activity
OIT41_16645	COG0745	RESPONSE REGULATOR receiver
OIT41_16655	COG2050	protein possibly involved in aromatic compounds catabolism
OIT41_16680	COG2030	dehydratase
OIT41_16680	COG1012	belongs to the aldehyde dehydrogenase family
OIT41_16690	COG1280	lysine exporter protein (LysE YggA)
OIT41_16705	COG1250	3-hydroxyacyl-CoA dehydrogenase
OIT41_16710	COG1024	Enoyl-CoA hydratase
OIT41_16740	COG1266	CAAX protease self-immunity
OIT41_16750	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
OIT41_16775	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OIT41_16785	COG0785	Cytochrome C biogenesis protein
OIT41_16795	COG0406	alpha-ribazole phosphatase activity
OIT41_16815	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
OIT41_16840	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OIT41_16845	COG1609	Transcriptional regulator
OIT41_16850	COG2186	Transcriptional regulator
OIT41_16860	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OIT41_16865	COG0640	Transcriptional regulator
OIT41_16870	COG0123	including yeast histone deacetylase and acetoin utilization protein
OIT41_16875	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OIT41_16880	COG0569	domain protein
OIT41_16885	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OIT41_16890	COG1082	Xylose isomerase domain protein TIM barrel
OIT41_16895	COG0248	Ppx GppA phosphatase
OIT41_16905	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OIT41_16905	COG1754	DNA topoisomerase type I activity
OIT41_16915	COG2890	protein-(glutamine-N5) methyltransferase activity
OIT41_16930	COG1054	Belongs to the UPF0176 family
OIT41_16940	COG1205	dead DEAH box helicase
OIT41_16940	COG1111	helicase
OIT41_17010	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OIT41_17020	COG1175	transmembrane transport
OIT41_17025	COG0395	ABC-type sugar transport system, permease component
OIT41_17035	COG1349	DNA-binding transcription factor activity
OIT41_17040	COG1609	Transcriptional regulator
OIT41_17050	COG1175	transmembrane transport
OIT41_17055	COG0395	ABC-type sugar transport system, permease component
OIT41_17070	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
OIT41_17100	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OIT41_17105	COG1408	metallophosphoesterase
OIT41_17110	COG1132	(ABC) transporter
OIT41_17115	COG1132	(ABC) transporter
OIT41_17135	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
OIT41_17140	COG0151	Belongs to the GarS family
OIT41_17160	COG1301	dicarboxylic acid transport
OIT41_17180	COG2066	Belongs to the glutaminase family
OIT41_17185	COG1028	Short-chain dehydrogenase reductase Sdr
OIT41_17195	COG1953	Uracil, thiamine, allantoin
OIT41_17200	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
OIT41_17215	COG3547	Transposase (IS116 IS110 IS902 family)
OIT41_17220	COG2080	2 iron, 2 sulfur cluster binding
OIT41_17220	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OIT41_17230	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
OIT41_17230	COG3608	succinylglutamate desuccinylase aspartoacylase
OIT41_17235	COG2252	PERMEase
OIT41_17240	COG0590	tRNA wobble adenosine to inosine editing
OIT41_17265	COG2233	PERMEase
OIT41_17270	COG1414	Transcriptional regulator
OIT41_17280	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OIT41_17290	COG3257	ureidoglycine aminohydrolase activity
OIT41_17295	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OIT41_17300	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OIT41_17315	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
OIT41_17320	COG3387	PFAM Glycoside hydrolase 15-related
OIT41_17325	COG0563	adenylate kinase activity
OIT41_17340	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OIT41_17340	COG4499	WXG100 protein secretion system (Wss), protein YukC
OIT41_17385	COG1028	Short-chain dehydrogenase reductase Sdr
OIT41_17425	COG2337	Toxic component of a toxin-antitoxin (TA) module
OIT41_17440	COG3958	Transketolase
OIT41_17445	COG3959	Transketolase, thiamine diphosphate binding domain
OIT41_17450	COG0477	Major facilitator Superfamily
OIT41_17455	COG1082	Xylose isomerase domain protein TIM barrel
OIT41_17460	COG1028	Short-chain dehydrogenase reductase Sdr
OIT41_17465	COG2376	Dihydroxyacetone kinase
OIT41_17470	COG0698	ribose 5-phosphate isomerase
OIT41_17475	COG3547	Transposase (IS116 IS110 IS902 family)
OIT41_17485	COG1609	Transcriptional regulator
OIT41_17495	COG1175	transmembrane transport
OIT41_17505	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
OIT41_17525	COG2971	BadF BadG BcrA BcrD
OIT41_17545	COG2267	carboxylic ester hydrolase activity
OIT41_17560	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OIT41_17615	COG0583	DNA-binding transcription factor activity
OIT41_17625	COG1301	dicarboxylic acid transport
OIT41_17630	COG1929	Belongs to the glycerate kinase type-1 family
OIT41_17650	COG1136	(ABC) transporter
OIT41_17660	COG3622	Belongs to the hyi family
OIT41_17665	COG2084	Dehydrogenase
OIT41_17670	COG3960	tartronate-semialdehyde synthase activity
OIT41_17675	COG1929	Belongs to the glycerate kinase type-1 family
OIT41_17680	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OIT41_17695	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
OIT41_17715	COG1012	belongs to the aldehyde dehydrogenase family
OIT41_17720	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
OIT41_17730	COG2186	Transcriptional regulator
OIT41_17750	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
OIT41_17765	COG0640	Transcriptional regulator
OIT41_17780	COG0542	response to heat
OIT41_17825	COG0028	Belongs to the TPP enzyme family
OIT41_17830	COG3304	Inner membrane component domain
OIT41_17835	COG1793	dna ligase
OIT41_17855	COG0135	phosphoribosylanthranilate isomerase activity
OIT41_17875	COG0667	Aldo Keto reductase
OIT41_17915	COG1473	amidohydrolase
OIT41_17920	COG0477	Major facilitator Superfamily
OIT41_17925	COG2807	transmembrane transport
OIT41_17930	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OIT41_17935	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OIT41_17965	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OIT41_17985	COG1172	Belongs to the binding-protein-dependent transport system permease family
OIT41_18010	COG1113	amino acid transport
OIT41_18015	COG0251	oxidation-reduction process
OIT41_18055	COG0789	Transcriptional regulator
OIT41_18060	COG0484	heat shock protein binding
OIT41_18065	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OIT41_18070	COG0443	Heat shock 70 kDa protein
OIT41_18090	COG2409	Drug exporters of the RND superfamily
OIT41_18095	COG1846	Transcriptional regulator
OIT41_18110	COG2226	methyltransferase
OIT41_18115	COG3795	YCII-related domain
OIT41_18120	COG4941	Belongs to the sigma-70 factor family
OIT41_18130	COG1280	lysine exporter protein (LysE YggA)
OIT41_18135	COG1609	Transcriptional regulator
OIT41_18140	COG1957	nucleoside hydrolase
OIT41_18145	COG0477	Major facilitator Superfamily
OIT41_18150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OIT41_18155	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OIT41_18165	COG1953	Uracil, thiamine, allantoin
OIT41_18195	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OIT41_18255	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
OIT41_18260	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OIT41_18270	COG1122	ATPase activity
OIT41_18275	COG4721	ABC-type cobalt transport system, permease component
OIT41_18295	COG2212	antiporter activity
OIT41_18305	COG0651	ATP synthesis coupled electron transport
OIT41_18310	COG1006	Multisubunit Na H antiporter MnhC subunit
OIT41_18315	COG2111	Na H antiporter
OIT41_18315	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OIT41_18330	COG1472	Belongs to the glycosyl hydrolase 3 family
OIT41_18335	COG0363	glucosamine-6-phosphate deaminase activity
OIT41_18340	COG2985	domain, Protein
OIT41_18340	COG0490	domain, Protein
OIT41_18345	COG0475	glutathione-regulated potassium exporter activity
OIT41_18360	COG0717	Belongs to the dCTP deaminase family
OIT41_18395	COG0583	DNA-binding transcription factor activity
OIT41_18400	COG1309	transcriptional regulator
OIT41_18410	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
OIT41_18420	COG3387	PFAM Glycoside hydrolase 15-related
OIT41_18425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIT41_18430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OIT41_18435	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OIT41_18445	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OIT41_18470	COG1136	(ABC) transporter
OIT41_18470	COG0577	efflux transmembrane transporter activity
OIT41_18490	COG3547	Transposase (IS116 IS110 IS902 family)
OIT41_18510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIT41_18535	COG1126	abc transporter atp-binding protein
OIT41_18540	COG0765	amino acid transport
OIT41_18555	COG3547	Transposase (IS116 IS110 IS902 family)
OIT41_18560	COG2318	DinB family
OIT41_18575	COG3336	cytochrome c oxidase
OIT41_18580	COG0776	regulation of translation
OIT41_18600	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OIT41_18605	COG0267	Belongs to the bacterial ribosomal protein bL33 family
OIT41_18610	COG0227	Belongs to the bacterial ribosomal protein bL28 family
OIT41_18615	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIT41_18615	COG1017	nitric oxide dioxygenase activity
OIT41_18665	COG1120	ATPase activity
OIT41_18670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OIT41_18675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OIT41_18715	COG3012	SEC-C Motif Domain Protein
OIT41_18730	COG0667	Aldo Keto reductase
OIT41_18745	COG0438	transferase activity, transferring glycosyl groups
OIT41_18760	COG2186	Transcriptional regulator
OIT41_18770	COG1027	Aspartate ammonia-lyase
OIT41_18780	COG0179	Fumarylacetoacetate (FAA) hydrolase
OIT41_18785	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OIT41_18820	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OIT41_18830	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OIT41_18850	COG1522	sequence-specific DNA binding
OIT41_18855	COG1280	lysine exporter protein (LysE YggA)
OIT41_18870	COG2197	response regulator
OIT41_18880	COG0281	malic enzyme
OIT41_18885	COG1309	transcriptional regulator
OIT41_18895	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OIT41_18900	COG0477	Major facilitator Superfamily
OIT41_18905	COG0477	Major facilitator Superfamily
OIT41_18910	COG2814	Major facilitator Superfamily
OIT41_18925	COG1113	amino acid transport
OIT41_18930	COG0246	Mannitol dehydrogenase
OIT41_18935	COG2213	PTS system mannitol-specific
OIT41_18935	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OIT41_18945	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OIT41_18950	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OIT41_18960	COG1960	acyl-CoA dehydrogenase activity
OIT41_18965	COG1309	transcriptional regulator
OIT41_18985	COG0686	Belongs to the AlaDH PNT family
OIT41_18995	COG3328	transposase activity
OIT41_19015	COG0673	inositol 2-dehydrogenase activity
OIT41_19020	COG1309	transcriptional regulator
OIT41_19040	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
OIT41_19045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIT41_19065	COG0508	dehydrogenase complex catalyzes the overall conversion of
OIT41_19070	COG0022	dehydrogenase e1 component
OIT41_19080	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OIT41_19085	COG1950	PFAM Membrane protein of
OIT41_19100	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OIT41_19120	COG1607	acyl-coa hydrolase
OIT41_19125	COG4221	oxidoreductase activity
OIT41_19130	COG0477	Major facilitator Superfamily
OIT41_19135	COG1984	allophanate hydrolase subunit 2
OIT41_19140	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
OIT41_19145	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
OIT41_19150	COG0583	DNA-binding transcription factor activity
OIT41_19160	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OIT41_19165	COG0436	Aminotransferase
OIT41_19180	COG3971	2-oxopent-4-enoate hydratase activity
OIT41_19195	COG1802	Transcriptional regulator
OIT41_19200	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OIT41_19210	COG0596	Alpha beta hydrolase
OIT41_19235	COG4221	oxidoreductase activity
OIT41_19250	COG1132	(ABC) transporter
OIT41_19265	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
OIT41_19270	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
OIT41_19275	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
OIT41_19305	COG1414	Transcriptional regulator
OIT41_19325	COG1970	mechanosensitive ion channel activity
OIT41_19335	COG0506	proline dehydrogenase activity
OIT41_19345	COG1278	Cold shock
OIT41_19350	COG1028	Short-chain dehydrogenase reductase Sdr
OIT41_19415	COG1414	Transcriptional regulator
OIT41_19420	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OIT41_19430	COG0183	Belongs to the thiolase family
OIT41_19435	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OIT41_19450	COG3485	protocatechuate 3,4-dioxygenase
OIT41_19455	COG3485	protocatechuate 3,4-dioxygenase
OIT41_19460	COG3185	4-Hydroxyphenylpyruvate dioxygenase
OIT41_19460	COG1082	Xylose isomerase domain protein TIM barrel
OIT41_19465	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OIT41_19470	COG1414	Transcriptional regulator
OIT41_19475	COG0477	Major facilitator Superfamily
OIT41_19485	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
OIT41_19500	COG2199	diguanylate cyclase activity
OIT41_19500	COG2200	EAL domain
OIT41_19505	COG1937	Protein conserved in bacteria
OIT41_19545	COG0534	Mate efflux family protein
OIT41_19550	COG1607	acyl-coa hydrolase
OIT41_19570	COG0305	Participates in initiation and elongation during chromosome replication
OIT41_19595	COG0359	binds to the 23S rRNA
OIT41_19600	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OIT41_19610	COG0360	Binds together with S18 to 16S ribosomal RNA
OIT41_19615	COG1742	UPF0060 membrane protein
OIT41_19625	COG1362	aminopeptidase activity
OIT41_19630	COG2197	response regulator
OIT41_19635	COG4585	Histidine kinase
OIT41_19645	COG1131	(ABC) transporter
OIT41_19660	COG1136	(ABC) transporter
OIT41_19665	COG1136	(ABC) transporter
OIT41_19665	COG0577	efflux transmembrane transporter activity
OIT41_19675	COG0738	Major facilitator superfamily
OIT41_19685	COG0488	(ABC) transporter
OIT41_19690	COG1309	transcriptional regulator
OIT41_19700	COG0768	penicillin binding
OIT41_19705	COG2197	response regulator
OIT41_19710	COG4585	Histidine kinase
OIT41_19720	COG1136	(ABC) transporter
OIT41_19725	COG1733	regulation of RNA biosynthetic process
OIT41_19730	COG2910	NAD(P)H-binding
OIT41_19750	COG0406	alpha-ribazole phosphatase activity
OIT41_19755	COG0617	tRNA 3'-terminal CCA addition
OIT41_19775	COG0492	ferredoxin-NADP+ reductase activity
OIT41_19780	COG3118	belongs to the thioredoxin family
OIT41_19785	COG3328	transposase activity
OIT41_19795	COG1192	Involved in chromosome partitioning
OIT41_19800	COG0357	Ribosomal RNA small subunit methyltransferase G
OIT41_19810	COG0706	membrane insertase activity
OIT41_19815	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
OIT41_19820	COG0594	ribonuclease P activity
OIT41_19825	COG0230	Belongs to the bacterial ribosomal protein bL34 family
OIT41_19875	COG0288	reversible hydration of carbon dioxide
OIT41_19950	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OIT41_19970	COG1921	L-seryl-tRNASec selenium transferase activity
OIT41_19980	COG0709	Synthesizes selenophosphate from selenide and ATP
OIT41_19990	COG0437	4 iron, 4 sulfur cluster binding
OIT41_20010	COG4974	Belongs to the 'phage' integrase family
OIT41_20030	COG2161	toxin-antitoxin pair type II binding
OIT41_20035	COG2026	Addiction module toxin, RelE StbE family
OIT41_20165	COG0515	serine threonine protein kinase
OIT41_20175	COG1349	DNA-binding transcription factor activity
OIT41_20180	COG0673	inositol 2-dehydrogenase activity
OIT41_20190	COG1175	transmembrane transport
OIT41_20195	COG0395	ABC-type sugar transport system, permease component
OIT41_20200	COG1028	Short-chain dehydrogenase reductase Sdr
OIT41_20205	COG4948	Mandelate Racemase Muconate Lactonizing
OIT41_20210	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OIT41_20215	COG3386	PFAM SMP-30 Gluconolaconase
OIT41_20220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OIT41_20225	COG3684	Belongs to the aldolase LacD family
OIT41_20230	COG1012	belongs to the aldehyde dehydrogenase family
OIT41_20250	COG0529	Catalyzes the synthesis of activated sulfate
OIT41_20250	COG2895	sulfate adenylyltransferase (ATP) activity
OIT41_20300	COG1846	Transcriptional regulator
OIT41_20305	COG2200	EAL domain
OIT41_20305	COG2199	diguanylate cyclase activity
OIT41_20340	COG2135	peptidase activity
OIT41_20345	COG0587	DNA-directed DNA polymerase activity
OIT41_20355	COG1192	Involved in chromosome partitioning
OIT41_20425	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
OIT41_20435	COG1192	Involved in chromosome partitioning
OIT41_20460	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OIT41_20495	COG2894	cell division
OIT41_20520	COG4152	abc transporter atp-binding protein
OIT41_20585	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OIT41_20650	COG0537	adenosine 5'-monophosphoramidase activity
OIT41_20675	COG3209	COG3209 Rhs family protein
OIT41_20710	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OIT41_20720	COG0492	ferredoxin-NADP+ reductase activity
OIT41_20725	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OIT41_20745	COG0456	acetyltransferase
OIT41_20765	COG2963	transposase activity
OIT41_20775	COG2801	Transposase and inactivated derivatives