locus-tag	class	description
CGK93_00010	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CGK93_00015	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CGK93_00020	COG0592	DNA-directed DNA polymerase activity
CGK93_00025	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CGK93_00030	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CGK93_00035	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
CGK93_00040	COG0187	DNA topoisomerase II activity
CGK93_00050	COG3266	domain, Protein
CGK93_00075	COG1215	transferase activity, transferring glycosyl groups
CGK93_00090	COG0705	Rhomboid family
CGK93_00100	COG2818	Glycosylase
CGK93_00110	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CGK93_00110	COG2169	Transcriptional regulator
CGK93_00130	COG3764	Sortase (surface protein transpeptidase)
CGK93_00140	COG0515	serine threonine protein kinase
CGK93_00145	COG0515	serine threonine protein kinase
CGK93_00150	COG0768	penicillin binding
CGK93_00165	COG1716	ATPase activity
CGK93_00170	COG1716	ATPase activity
CGK93_00180	COG2188	Transcriptional regulator
CGK93_00190	COG2197	response regulator
CGK93_00195	COG4585	Histidine kinase
CGK93_00235	COG1505	serine-type exopeptidase activity
CGK93_00265	COG1132	(ABC) transporter
CGK93_00270	COG1132	(ABC) transporter
CGK93_00275	COG1609	Transcriptional regulator
CGK93_00290	COG1120	ATPase activity
CGK93_00305	COG0346	lactoylglutathione lyase activity
CGK93_00320	COG2186	Transcriptional regulator
CGK93_00325	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CGK93_00335	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CGK93_00340	COG4770	biotin carboxylase activity
CGK93_00345	COG0277	FAD linked oxidase domain protein
CGK93_00350	COG1609	Transcriptional regulator
CGK93_00355	COG0385	Bile acid
CGK93_00360	COG0659	secondary active sulfate transmembrane transporter activity
CGK93_00380	COG0435	Glutathione S-transferase
CGK93_00385	COG0561	phosphatase activity
CGK93_00420	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CGK93_00425	COG1929	Belongs to the glycerate kinase type-1 family
CGK93_00455	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CGK93_00510	COG0506	proline dehydrogenase activity
CGK93_00535	COG1309	transcriptional regulator
CGK93_00540	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_00545	COG1309	transcriptional regulator
CGK93_00555	COG0693	protein deglycase activity
CGK93_00585	COG0395	ABC-type sugar transport system, permease component
CGK93_00610	COG1131	(ABC) transporter
CGK93_00620	COG2197	response regulator
CGK93_00625	COG4585	Histidine kinase
CGK93_00630	COG4585	Histidine kinase
CGK93_00640	COG2233	PERMEase
CGK93_00645	COG0778	Nitroreductase
CGK93_00670	COG3104	oligopeptide transport
CGK93_00680	COG3340	Belongs to the peptidase S51 family
CGK93_00685	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CGK93_00685	COG0425	Belongs to the sulfur carrier protein TusA family
CGK93_00690	COG0077	Prephenate dehydratase
CGK93_00700	COG1597	lipid kinase activity
CGK93_00705	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CGK93_00725	COG3973	AAA domain
CGK93_00730	COG0561	phosphatase activity
CGK93_00750	COG1191	sigma factor activity
CGK93_00760	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CGK93_00765	COG0859	PFAM glycosyl transferase family 9
CGK93_00775	COG0438	transferase activity, transferring glycosyl groups
CGK93_00780	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CGK93_00785	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CGK93_00785	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CGK93_00790	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_00800	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CGK93_00800	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CGK93_00870	COG0037	tRNA processing
CGK93_00885	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CGK93_00890	COG0302	gtp cyclohydrolase
CGK93_00900	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CGK93_00930	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CGK93_00935	COG2814	Major facilitator Superfamily
CGK93_01010	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CGK93_01020	COG0542	response to heat
CGK93_01030	COG0823	Involved in the tonB-independent uptake of proteins
CGK93_01030	COG1506	peptidase
CGK93_01040	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CGK93_01060	COG1335	isochorismatase
CGK93_01065	COG2376	Dihydroxyacetone kinase
CGK93_01070	COG1461	Dihydroxyacetone kinase
CGK93_01075	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CGK93_01080	COG3237	CsbD-like
CGK93_01105	COG1301	dicarboxylic acid transport
CGK93_01115	COG1194	a g-specific adenine glycosylase
CGK93_01125	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CGK93_01140	COG3665	Urea carboxylase-associated protein
CGK93_01170	COG0671	phosphoesterase, PA-phosphatase related
CGK93_01195	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CGK93_01260	COG1609	Transcriptional regulator
CGK93_01295	COG0831	urea catabolic process
CGK93_01300	COG0832	Belongs to the urease beta subunit family
CGK93_01305	COG0804	urea catabolic process
CGK93_01310	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CGK93_01315	COG0830	nickel cation binding
CGK93_01320	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CGK93_01325	COG0829	nickel cation binding
CGK93_01330	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CGK93_01340	COG1595	DNA-templated transcription, initiation
CGK93_01370	COG0656	L-ascorbic acid biosynthetic process
CGK93_01380	COG0667	Aldo Keto reductase
CGK93_01385	COG0656	L-ascorbic acid biosynthetic process
CGK93_01395	COG3360	Dodecin
CGK93_01400	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_01410	COG0028	Belongs to the TPP enzyme family
CGK93_01415	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CGK93_01420	COG1233	COG1233 Phytoene dehydrogenase and related
CGK93_01425	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CGK93_01450	COG2186	Transcriptional regulator
CGK93_01455	COG2267	carboxylic ester hydrolase activity
CGK93_01465	COG2084	Dehydrogenase
CGK93_01470	COG2610	gluconate transmembrane transporter activity
CGK93_01525	COG0076	glutamate decarboxylase activity
CGK93_01530	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CGK93_01550	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_01560	COG1289	transmembrane transporter activity
CGK93_01575	COG0346	lactoylglutathione lyase activity
CGK93_01590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CGK93_01595	COG0477	Major facilitator Superfamily
CGK93_01600	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CGK93_01610	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CGK93_01640	COG3285	dna ligase
CGK93_01640	COG1793	dna ligase
CGK93_01645	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CGK93_01680	COG3226	Transcriptional regulator
CGK93_01690	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CGK93_01690	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CGK93_01690	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CGK93_01700	COG1349	DNA-binding transcription factor activity
CGK93_01720	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CGK93_01745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CGK93_01765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CGK93_01775	COG1126	abc transporter atp-binding protein
CGK93_01840	COG1846	Transcriptional regulator
CGK93_01865	COG0142	geranyltranstransferase activity
CGK93_01870	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CGK93_01900	COG0179	Fumarylacetoacetate (FAA) hydrolase
CGK93_01915	COG2814	Major facilitator Superfamily
CGK93_01920	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CGK93_01925	COG4335	DNA alkylation repair
CGK93_01935	COG0129	dihydroxy-acid dehydratase activity
CGK93_01950	COG2197	response regulator
CGK93_01965	COG5006	permease, DMT superfamily
CGK93_01985	COG2066	Belongs to the glutaminase family
CGK93_02005	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CGK93_02025	COG2733	membrane
CGK93_02095	COG1132	(ABC) transporter
CGK93_02100	COG1132	(ABC) transporter
CGK93_02105	COG2207	Transcriptional regulator
CGK93_02120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGK93_02130	COG1120	ATPase activity
CGK93_02135	COG0583	DNA-binding transcription factor activity
CGK93_02145	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_02150	COG1733	regulation of RNA biosynthetic process
CGK93_02155	COG0702	epimerase
CGK93_02175	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CGK93_02205	COG0010	Belongs to the arginase family
CGK93_02210	COG2252	PERMEase
CGK93_02235	COG0574	Belongs to the PEP-utilizing enzyme family
CGK93_02235	COG3848	Pyruvate phosphate dikinase
CGK93_02250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CGK93_02285	COG1302	Protein conserved in bacteria
CGK93_02330	COG1653	transport
CGK93_02335	COG1175	transmembrane transport
CGK93_02340	COG0395	ABC-type sugar transport system, permease component
CGK93_02345	COG1609	Transcriptional regulator
CGK93_02365	COG2197	response regulator
CGK93_02370	COG4585	Histidine kinase
CGK93_02385	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CGK93_02395	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CGK93_02415	COG4585	Histidine kinase
CGK93_02435	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CGK93_02450	COG1063	alcohol dehydrogenase
CGK93_02460	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CGK93_02465	COG3404	Formiminotransferase-cyclodeaminase
CGK93_02480	COG1802	Transcriptional regulator
CGK93_02485	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CGK93_02495	COG0583	DNA-binding transcription factor activity
CGK93_02520	COG0415	Belongs to the DNA photolyase family
CGK93_02530	COG1024	Enoyl-CoA hydratase
CGK93_02595	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CGK93_02600	COG1960	acyl-CoA dehydrogenase activity
CGK93_02635	COG1280	lysine exporter protein (LysE YggA)
CGK93_02705	COG1621	beta-fructofuranosidase activity
CGK93_02710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CGK93_02720	COG0789	Transcriptional regulator
CGK93_02735	COG1012	belongs to the aldehyde dehydrogenase family
CGK93_02740	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CGK93_02750	COG0531	amino acid
CGK93_02755	COG2186	Transcriptional regulator
CGK93_02760	COG3835	regulator
CGK93_02765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CGK93_02770	COG0765	amino acid transport
CGK93_02775	COG1126	abc transporter atp-binding protein
CGK93_02785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CGK93_02790	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CGK93_02795	COG1609	Transcriptional regulator
CGK93_02810	COG0747	negative chemotaxis
CGK93_02820	COG0444	Belongs to the ABC transporter superfamily
CGK93_02835	COG0673	inositol 2-dehydrogenase activity
CGK93_02840	COG1609	Transcriptional regulator
CGK93_02845	COG1904	glucuronate isomerase
CGK93_02850	COG0246	Mannitol dehydrogenase
CGK93_02855	COG4948	Mandelate Racemase Muconate Lactonizing
CGK93_02865	COG4213	ABC transporter substrate-binding protein
CGK93_02870	COG1129	ABC transporter
CGK93_02875	COG4214	carbohydrate transport
CGK93_02880	COG1609	Transcriptional regulator
CGK93_02885	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CGK93_02930	COG1120	ATPase activity
CGK93_02935	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGK93_02940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGK93_02945	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CGK93_02980	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CGK93_02995	COG2814	Major facilitator Superfamily
CGK93_03015	COG1309	transcriptional regulator
CGK93_03055	COG0583	DNA-binding transcription factor activity
CGK93_03060	COG0039	L-malate dehydrogenase activity
CGK93_03065	COG0477	Major facilitator Superfamily
CGK93_03070	COG2267	carboxylic ester hydrolase activity
CGK93_03080	COG3263	regulation of cellular component size
CGK93_03125	COG0765	amino acid transport
CGK93_03130	COG1126	abc transporter atp-binding protein
CGK93_03135	COG0673	inositol 2-dehydrogenase activity
CGK93_03180	COG1832	CoA-binding protein
CGK93_03190	COG2315	Protein conserved in bacteria
CGK93_03205	COG1175	transmembrane transport
CGK93_03230	COG2368	4-hydroxyphenylacetate
CGK93_03290	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CGK93_03295	COG0047	phosphoribosylformylglycinamidine synthase activity
CGK93_03315	COG3546	catalase activity
CGK93_03320	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CGK93_03350	COG1846	Transcriptional regulator
CGK93_03365	COG1174	glycine betaine transport
CGK93_03370	COG0517	IMP dehydrogenase activity
CGK93_03370	COG1125	glycine betaine transport
CGK93_03375	COG1174	glycine betaine transport
CGK93_03380	COG1732	Glycine betaine
CGK93_03390	COG4948	Mandelate Racemase Muconate Lactonizing
CGK93_03395	COG1012	belongs to the aldehyde dehydrogenase family
CGK93_03400	COG2084	Dehydrogenase
CGK93_03415	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_03425	COG5416	Lipopolysaccharide assembly protein A domain
CGK93_03440	COG2814	Major facilitator Superfamily
CGK93_03470	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CGK93_03485	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CGK93_03500	COG1012	belongs to the aldehyde dehydrogenase family
CGK93_03525	COG0739	heme binding
CGK93_03525	COG0741	lytic transglycosylase activity
CGK93_03525	COG1196	nuclear chromosome segregation
CGK93_03530	COG0386	Belongs to the glutathione peroxidase family
CGK93_03585	COG1609	Transcriptional regulator
CGK93_03590	COG0673	inositol 2-dehydrogenase activity
CGK93_03615	COG0395	ABC-type sugar transport system, permease component
CGK93_03630	COG0438	transferase activity, transferring glycosyl groups
CGK93_03655	COG1621	beta-fructofuranosidase activity
CGK93_03665	COG0395	ABC-type sugar transport system, permease component
CGK93_03690	COG1621	beta-fructofuranosidase activity
CGK93_03695	COG0589	response to stress
CGK93_03715	COG3290	protein histidine kinase activity
CGK93_03735	COG0546	phosphoglycolate phosphatase activity
CGK93_03750	COG2076	Multidrug Resistance protein
CGK93_03755	COG0590	tRNA wobble adenosine to inosine editing
CGK93_03760	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CGK93_03775	COG4702	Belongs to the UPF0303 family
CGK93_03795	COG0673	inositol 2-dehydrogenase activity
CGK93_03825	COG1476	TRANSCRIPTIONal
CGK93_03835	COG1309	transcriptional regulator
CGK93_03845	COG0351	phosphomethylpyrimidine kinase
CGK93_03855	COG0642	Histidine kinase
CGK93_03860	COG0745	RESPONSE REGULATOR receiver
CGK93_03865	COG0477	Major facilitator Superfamily
CGK93_03870	COG1090	epimerase
CGK93_03885	COG0343	queuine tRNA-ribosyltransferase activity
CGK93_03925	COG1960	acyl-CoA dehydrogenase activity
CGK93_03955	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CGK93_03965	COG1215	transferase activity, transferring glycosyl groups
CGK93_03980	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CGK93_03990	COG0586	Pfam SNARE associated Golgi protein
CGK93_04000	COG0564	pseudouridine synthase activity
CGK93_04030	COG2364	Membrane
CGK93_04045	COG1215	transferase activity, transferring glycosyl groups
CGK93_04055	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CGK93_04060	COG1201	RNA secondary structure unwinding
CGK93_04085	COG0515	serine threonine protein kinase
CGK93_04160	COG0438	transferase activity, transferring glycosyl groups
CGK93_04170	COG0590	tRNA wobble adenosine to inosine editing
CGK93_04175	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CGK93_04200	COG2205	protein histidine kinase activity
CGK93_04205	COG0745	RESPONSE REGULATOR receiver
CGK93_04215	COG2062	phosphohistidine phosphatase, SixA
CGK93_04225	COG0583	DNA-binding transcription factor activity
CGK93_04230	COG0697	spore germination
CGK93_04245	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CGK93_04255	COG0601	transmembrane transport
CGK93_04265	COG4172	Belongs to the ABC transporter superfamily
CGK93_04270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CGK93_04280	COG1309	transcriptional regulator
CGK93_04285	COG1511	domain protein
CGK93_04305	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CGK93_04310	COG1940	carbohydrate kinase activity
CGK93_04320	COG4608	Belongs to the ABC transporter superfamily
CGK93_04325	COG0444	Belongs to the ABC transporter superfamily
CGK93_04335	COG0747	negative chemotaxis
CGK93_04355	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CGK93_04380	COG0514	ATP-dependent DNA helicase (RecQ)
CGK93_04385	COG2814	Major facilitator Superfamily
CGK93_04395	COG1505	serine-type exopeptidase activity
CGK93_04435	COG1966	Carbon starvation protein
CGK93_04455	COG0656	L-ascorbic acid biosynthetic process
CGK93_04465	COG0154	amidase activity
CGK93_04480	COG1473	amidohydrolase
CGK93_04505	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CGK93_04510	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CGK93_04530	COG0588	phosphoglycerate mutase activity
CGK93_04540	COG5002	protein histidine kinase activity
CGK93_04560	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CGK93_04565	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CGK93_04575	COG0215	cysteine-tRNA ligase activity
CGK93_04610	COG0366	Alpha amylase catalytic
CGK93_04620	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CGK93_04650	COG1609	Transcriptional regulator
CGK93_04670	COG3833	ABC-type maltose transport systems, permease component
CGK93_04675	COG0366	Alpha amylase catalytic
CGK93_04680	COG0277	FAD linked oxidase domain protein
CGK93_04695	COG0402	S-adenosylhomocysteine deaminase activity
CGK93_04715	COG3842	ATPase activity
CGK93_04740	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CGK93_04750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CGK93_04770	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CGK93_04775	COG2814	Major facilitator Superfamily
CGK93_04870	COG3201	nicotinamide mononucleotide transporter
CGK93_04885	COG0586	Pfam SNARE associated Golgi protein
CGK93_04895	COG0395	ABC-type sugar transport system, permease component
CGK93_04900	COG1175	transmembrane transport
CGK93_04915	COG1621	beta-fructofuranosidase activity
CGK93_04925	COG0514	ATP-dependent DNA helicase (RecQ)
CGK93_04930	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CGK93_04980	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_04990	COG1960	acyl-CoA dehydrogenase activity
CGK93_05015	COG0579	oxidoreductase
CGK93_05055	COG0024	Methionine aminopeptidase
CGK93_05070	COG0492	ferredoxin-NADP+ reductase activity
CGK93_05080	COG1473	amidohydrolase
CGK93_05090	COG0477	Major facilitator Superfamily
CGK93_05100	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CGK93_05100	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CGK93_05105	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CGK93_05110	COG0509	glycine decarboxylation via glycine cleavage system
CGK93_05120	COG1864	DNA RNA non-specific endonuclease
CGK93_05120	COG3591	Belongs to the peptidase S1B family
CGK93_05150	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CGK93_05170	COG0459	protein refolding
CGK93_05185	COG2205	protein histidine kinase activity
CGK93_05190	COG0745	RESPONSE REGULATOR receiver
CGK93_05200	COG0583	DNA-binding transcription factor activity
CGK93_05210	COG2132	Multicopper oxidase
CGK93_05235	COG1278	Cold shock
CGK93_05245	COG2814	Major facilitator Superfamily
CGK93_05260	COG0739	heme binding
CGK93_05265	COG1388	LysM domain
CGK93_05265	COG0791	NLP P60 protein
CGK93_05265	COG3103	Sh3 type 3 domain protein
CGK93_05280	COG0746	molybdenum cofactor guanylyltransferase activity
CGK93_05295	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CGK93_05315	COG1126	abc transporter atp-binding protein
CGK93_05325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CGK93_05340	COG0488	(ABC) transporter
CGK93_05345	COG1132	(ABC) transporter
CGK93_05375	COG0483	inositol monophosphate 1-phosphatase activity
CGK93_05400	COG0045	succinate-CoA ligase (ADP-forming) activity
CGK93_05415	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CGK93_05455	COG1396	sequence-specific DNA binding
CGK93_05470	COG0028	Belongs to the TPP enzyme family
CGK93_05535	COG1175	transmembrane transport
CGK93_05545	COG1609	Transcriptional regulator
CGK93_05560	COG1609	Transcriptional regulator
CGK93_05590	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CGK93_05620	COG0739	heme binding
CGK93_05620	COG0741	lytic transglycosylase activity
CGK93_05620	COG1196	nuclear chromosome segregation
CGK93_05630	COG1401	restriction endodeoxyribonuclease activity
CGK93_05645	COG5002	protein histidine kinase activity
CGK93_05650	COG0745	RESPONSE REGULATOR receiver
CGK93_05670	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CGK93_05685	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_05720	COG1902	pentaerythritol trinitrate reductase activity
CGK93_05735	COG2376	Dihydroxyacetone kinase
CGK93_05740	COG0698	ribose 5-phosphate isomerase
CGK93_05745	COG1250	3-hydroxyacyl-CoA dehydrogenase
CGK93_05750	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_05755	COG2271	Major facilitator Superfamily
CGK93_05760	COG0149	triose-phosphate isomerase activity
CGK93_05815	COG3103	Sh3 type 3 domain protein
CGK93_05815	COG0366	Alpha amylase catalytic
CGK93_05820	COG1254	Belongs to the acylphosphatase family
CGK93_05825	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
CGK93_05835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CGK93_05840	COG2186	Transcriptional regulator
CGK93_05850	COG1957	nucleoside hydrolase
CGK93_05855	COG0640	Transcriptional regulator
CGK93_05865	COG4209	transmembrane transport
CGK93_05870	COG0395	ABC-type sugar transport system, permease component
CGK93_05885	COG0402	S-adenosylhomocysteine deaminase activity
CGK93_05920	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CGK93_05930	COG0673	inositol 2-dehydrogenase activity
CGK93_05945	COG1609	Transcriptional regulator
CGK93_05965	COG2365	Tyrosine phosphatase family
CGK93_05970	COG3639	organic phosphonate transmembrane transporter activity
CGK93_05975	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CGK93_05985	COG0477	Major facilitator Superfamily
CGK93_06000	COG0604	alcohol dehydrogenase
CGK93_06010	COG1309	transcriptional regulator
CGK93_06015	COG0861	Integral membrane protein TerC family
CGK93_06080	COG1846	Transcriptional regulator
CGK93_06085	COG0697	spore germination
CGK93_06125	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CGK93_06125	COG0515	serine threonine protein kinase
CGK93_06140	COG1401	restriction endodeoxyribonuclease activity
CGK93_06185	COG0531	amino acid
CGK93_06215	COG1278	Cold shock
CGK93_06230	COG0477	Major facilitator Superfamily
CGK93_06235	COG0501	Belongs to the peptidase M48B family
CGK93_06250	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CGK93_06275	COG0789	Transcriptional regulator
CGK93_06285	COG0484	heat shock protein binding
CGK93_06315	COG2814	Major facilitator Superfamily
CGK93_06320	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CGK93_06330	COG0138	bifunctional purine biosynthesis protein purh
CGK93_06345	COG2838	Isocitrate dehydrogenase
CGK93_06355	COG3639	organic phosphonate transmembrane transporter activity
CGK93_06360	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CGK93_06375	COG2188	Transcriptional regulator
CGK93_06380	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CGK93_06410	COG0577	efflux transmembrane transporter activity
CGK93_06410	COG1136	(ABC) transporter
CGK93_06415	COG0577	efflux transmembrane transporter activity
CGK93_06415	COG1136	(ABC) transporter
CGK93_06420	COG1136	(ABC) transporter
CGK93_06425	COG1136	(ABC) transporter
CGK93_06425	COG0577	efflux transmembrane transporter activity
CGK93_06430	COG4213	ABC transporter substrate-binding protein
CGK93_06440	COG1129	ABC transporter
CGK93_06450	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CGK93_06460	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CGK93_06465	COG0531	amino acid
CGK93_06495	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CGK93_06500	COG1131	(ABC) transporter
CGK93_06535	COG0180	Tryptophanyl-tRNA synthetase
CGK93_06570	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CGK93_06585	COG2009	succinate dehydrogenase
CGK93_06595	COG1473	amidohydrolase
CGK93_06595	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CGK93_06600	COG1846	Transcriptional regulator
CGK93_06605	COG1764	response to oxidative stress
CGK93_06610	COG2130	NADP-dependent
CGK93_06650	COG0586	Pfam SNARE associated Golgi protein
CGK93_06655	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CGK93_06660	COG3956	TIGRFAM MazG family protein
CGK93_06665	COG0148	phosphopyruvate hydratase activity
CGK93_06690	COG1252	NADH dehydrogenase
CGK93_06730	COG0559	Belongs to the binding-protein-dependent transport system permease family
CGK93_06745	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CGK93_06755	COG2017	converts alpha-aldose to the beta-anomer
CGK93_06765	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CGK93_06775	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CGK93_06785	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CGK93_06795	COG1331	Highly conserved protein containing a thioredoxin domain
CGK93_06805	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CGK93_06810	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CGK93_06845	COG0114	fumarate hydratase activity
CGK93_06850	COG0288	reversible hydration of carbon dioxide
CGK93_06860	COG1494	fructose-1,6-bisphosphatase
CGK93_06870	COG1482	cell wall glycoprotein biosynthetic process
CGK93_06930	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CGK93_06945	COG1357	PFAM Pentapeptide repeats (8 copies)
CGK93_07000	COG0714	Associated with various cellular activities
CGK93_07005	COG0084	hydrolase, TatD family'
CGK93_07010	COG3583	domain protein
CGK93_07015	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CGK93_07020	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CGK93_07025	COG0488	(ABC) transporter
CGK93_07035	COG1309	transcriptional regulator
CGK93_07045	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CGK93_07050	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CGK93_07055	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CGK93_07060	COG0193	aminoacyl-tRNA hydrolase activity
CGK93_07105	COG0702	epimerase
CGK93_07115	COG1988	membrane-bound metal-dependent
CGK93_07125	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CGK93_07175	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CGK93_07235	COG0456	acetyltransferase
CGK93_07245	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CGK93_07255	COG1648	precorrin-2 dehydrogenase activity
CGK93_07255	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CGK93_07270	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CGK93_07275	COG1621	beta-fructofuranosidase activity
CGK93_07305	COG0243	molybdopterin cofactor binding
CGK93_07310	COG2223	nitrite transmembrane transporter activity
CGK93_07315	COG0477	Major facilitator Superfamily
CGK93_07320	COG4770	biotin carboxylase activity
CGK93_07325	COG0424	maF-like protein
CGK93_07330	COG2409	Drug exporters of the RND superfamily
CGK93_07335	COG1309	transcriptional regulator
CGK93_07340	COG0393	Putative heavy-metal-binding
CGK93_07390	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_07395	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CGK93_07395	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CGK93_07420	COG0714	Associated with various cellular activities
CGK93_07440	COG0631	protein serine/threonine phosphatase activity
CGK93_07460	COG1674	ftsk spoiiie
CGK93_07470	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CGK93_07475	COG0483	inositol monophosphate 1-phosphatase activity
CGK93_07495	COG0251	oxidation-reduction process
CGK93_07500	COG4565	transcriptional regulatory protein
CGK93_07510	COG2851	Citrate transporter
CGK93_07515	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CGK93_07520	COG0154	amidase activity
CGK93_07525	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CGK93_07535	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CGK93_07540	COG4209	transmembrane transport
CGK93_07545	COG0395	ABC-type sugar transport system, permease component
CGK93_07570	COG1063	alcohol dehydrogenase
CGK93_07575	COG0156	8-amino-7-oxononanoate synthase activity
CGK93_07590	COG1228	amidohydrolase
CGK93_07595	COG0366	Alpha amylase catalytic
CGK93_07595	COG1470	cell adhesion involved in biofilm formation
CGK93_07600	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CGK93_07605	COG1940	carbohydrate kinase activity
CGK93_07615	COG0191	fructose-bisphosphate aldolase activity
CGK93_07640	COG2873	o-acetylhomoserine
CGK93_07645	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CGK93_07680	COG0423	glycine-tRNA ligase activity
CGK93_07705	COG0358	DNA primase activity
CGK93_07725	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CGK93_07730	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CGK93_07740	COG2814	Major facilitator Superfamily
CGK93_07750	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CGK93_07780	COG0052	Belongs to the universal ribosomal protein uS2 family
CGK93_07785	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CGK93_07790	COG0528	UMP kinase activity
CGK93_07795	COG0233	cytoplasmic translational termination
CGK93_07800	COG0575	Belongs to the CDS family
CGK93_07815	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CGK93_07825	COG3279	Response regulator of the LytR AlgR family
CGK93_07830	COG3275	phosphorelay sensor kinase activity
CGK93_07840	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CGK93_07845	COG1796	DNA polymerase
CGK93_07845	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CGK93_07865	COG1522	sequence-specific DNA binding
CGK93_07875	COG0022	dehydrogenase e1 component
CGK93_07880	COG0508	dehydrogenase complex catalyzes the overall conversion of
CGK93_07885	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CGK93_07900	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CGK93_07910	COG1960	acyl-CoA dehydrogenase activity
CGK93_07935	COG0673	inositol 2-dehydrogenase activity
CGK93_07945	COG0673	inositol 2-dehydrogenase activity
CGK93_07955	COG1175	transmembrane transport
CGK93_07960	COG1653	transport
CGK93_07965	COG1609	Transcriptional regulator
CGK93_07975	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CGK93_07980	COG0750	zinc metalloprotease
CGK93_07990	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CGK93_08005	COG0442	prolyl-tRNA aminoacylation
CGK93_08015	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CGK93_08020	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
CGK93_08035	COG0779	Required for maturation of 30S ribosomal subunits
CGK93_08050	COG0481	GTPase activity
CGK93_08050	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CGK93_08055	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CGK93_08060	COG0590	tRNA wobble adenosine to inosine editing
CGK93_08070	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CGK93_08090	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CGK93_08095	COG1185	polyribonucleotide nucleotidyltransferase activity
CGK93_08100	COG0612	Peptidase, M16
CGK93_08120	COG0745	RESPONSE REGULATOR receiver
CGK93_08125	COG2205	protein histidine kinase activity
CGK93_08145	COG0521	Mo-molybdopterin cofactor biosynthetic process
CGK93_08155	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CGK93_08180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CGK93_08185	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CGK93_08190	COG1674	ftsk spoiiie
CGK93_08200	COG1546	Belongs to the CinA family
CGK93_08200	COG1058	Belongs to the CinA family
CGK93_08205	COG1396	sequence-specific DNA binding
CGK93_08220	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CGK93_08225	COG2137	regulation of response to DNA damage stimulus
CGK93_08230	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CGK93_08235	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CGK93_08240	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CGK93_08245	COG2813	Specifically methylates the guanine in position
CGK93_08250	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CGK93_08260	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CGK93_08265	COG1388	LysM domain
CGK93_08270	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CGK93_08275	COG0131	Imidazoleglycerol-phosphate dehydratase
CGK93_08280	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CGK93_08285	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CGK93_08305	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CGK93_08310	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CGK93_08315	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CGK93_08320	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CGK93_08325	COG2814	Major facilitator Superfamily
CGK93_08340	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CGK93_08360	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CGK93_08365	COG0072	phenylalanine-tRNA ligase activity
CGK93_08365	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CGK93_08370	COG3591	Belongs to the peptidase S1B family
CGK93_08440	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CGK93_08445	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CGK93_08450	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CGK93_08455	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CGK93_08460	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CGK93_08465	COG1438	arginine binding
CGK93_08470	COG0137	argininosuccinate synthase activity
CGK93_08475	COG0165	Argininosuccinate lyase
CGK93_08490	COG2094	Belongs to the DNA glycosylase MPG family
CGK93_08500	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CGK93_08525	COG0647	UMP catabolic process
CGK93_08540	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CGK93_08545	COG0497	DNA recombination
CGK93_08550	COG0504	CTP synthase activity
CGK93_08570	COG0494	nUDIX hydrolase
CGK93_08580	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CGK93_08585	COG2079	MmgE PrpD family protein
CGK93_08610	COG3290	protein histidine kinase activity
CGK93_08615	COG1301	dicarboxylic acid transport
CGK93_08625	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CGK93_08630	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CGK93_08645	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CGK93_08655	COG1160	GTP binding
CGK93_08665	COG1846	Transcriptional regulator
CGK93_08670	COG2814	Major facilitator Superfamily
CGK93_08680	COG0509	glycine decarboxylation via glycine cleavage system
CGK93_08685	COG1716	ATPase activity
CGK93_08710	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CGK93_08720	COG1940	carbohydrate kinase activity
CGK93_08745	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CGK93_08750	COG2815	serine threonine protein kinase
CGK93_08750	COG0515	serine threonine protein kinase
CGK93_08755	COG3942	CHAP domain
CGK93_08755	COG1388	LysM domain
CGK93_08765	COG0142	geranyltranstransferase activity
CGK93_08785	COG2001	Belongs to the MraZ family
CGK93_08790	COG0275	rRNA processing
CGK93_08800	COG0768	penicillin binding
CGK93_08805	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CGK93_08815	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CGK93_08820	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CGK93_08830	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CGK93_08835	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CGK93_08845	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CGK93_08855	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CGK93_08860	COG1799	cell septum assembly
CGK93_08875	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CGK93_08900	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CGK93_08905	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CGK93_08910	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_08935	COG0174	glutamine synthetase
CGK93_08940	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CGK93_08985	COG1045	serine acetyltransferase
CGK93_08990	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CGK93_08995	COG0321	lipoyl(octanoyl) transferase activity
CGK93_09005	COG1090	epimerase
CGK93_09015	COG1764	response to oxidative stress
CGK93_09030	COG0508	dehydrogenase complex catalyzes the overall conversion of
CGK93_09035	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CGK93_09040	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CGK93_09060	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CGK93_09090	COG1271	oxidase subunit
CGK93_09095	COG1294	oxidase, subunit
CGK93_09100	COG4988	ABC transporter
CGK93_09120	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CGK93_09125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CGK93_09125	COG1042	CoA-binding domain protein
CGK93_09125	COG0045	succinate-CoA ligase (ADP-forming) activity
CGK93_09140	COG1435	thymidine kinase activity
CGK93_09160	COG0756	dUTP diphosphatase activity
CGK93_09185	COG0569	domain protein
CGK93_09190	COG0531	amino acid
CGK93_09195	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CGK93_09230	COG1250	3-hydroxyacyl-CoA dehydrogenase
CGK93_09230	COG1024	Enoyl-CoA hydratase
CGK93_09235	COG0183	Belongs to the thiolase family
CGK93_09265	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CGK93_09280	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CGK93_09300	COG3135	benzoate transporter
CGK93_09310	COG0531	amino acid
CGK93_09400	COG3422	double-strand break repair
CGK93_09505	COG0210	DNA helicase
CGK93_09555	COG0242	peptide deformylase activity
CGK93_09560	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CGK93_09570	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CGK93_09590	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CGK93_09590	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CGK93_09600	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CGK93_09605	COG0140	phosphoribosyl-ATP diphosphatase activity
CGK93_09610	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CGK93_09615	COG0107	imidazoleglycerol-phosphate synthase activity
CGK93_09625	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CGK93_09645	COG0134	indole-3-glycerol-phosphate synthase activity
CGK93_09650	COG0133	tryptophan synthase activity
CGK93_09655	COG0159	tryptophan synthase activity
CGK93_09660	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CGK93_09870	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CGK93_09885	COG0384	phenazine biosynthesis protein PhzF
CGK93_09900	COG2084	Dehydrogenase
CGK93_09905	COG1082	Xylose isomerase domain protein TIM barrel
CGK93_09910	COG0149	triose-phosphate isomerase activity
CGK93_09915	COG0698	ribose 5-phosphate isomerase
CGK93_09920	COG2376	Dihydroxyacetone kinase
CGK93_09925	COG2186	Transcriptional regulator
CGK93_09935	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_09970	COG1414	Transcriptional regulator
CGK93_09980	COG1917	Cupin 2, conserved barrel domain protein
CGK93_10010	COG2272	Belongs to the type-B carboxylesterase lipase family
CGK93_10020	COG2723	6-phospho-beta-galactosidase activity
CGK93_10025	COG2211	Major facilitator Superfamily
CGK93_10040	COG3958	Transketolase
CGK93_10045	COG3959	Transketolase, thiamine diphosphate binding domain
CGK93_10055	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_10065	COG2814	Major facilitator Superfamily
CGK93_10075	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CGK93_10080	COG1414	Transcriptional regulator
CGK93_10095	COG3384	dioxygenase
CGK93_10105	COG0066	3-isopropylmalate dehydratase activity
CGK93_10115	COG2814	Major facilitator Superfamily
CGK93_10125	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_10150	COG3395	kinase activity
CGK93_10155	COG0235	Class ii aldolase
CGK93_10160	COG2508	Transcriptional regulator
CGK93_10210	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_10245	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CGK93_10250	COG2076	Multidrug Resistance protein
CGK93_10255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CGK93_10270	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CGK93_10275	COG0626	cystathionine gamma-synthase activity
CGK93_10295	COG0251	oxidation-reduction process
CGK93_10300	COG0531	amino acid
CGK93_10320	COG1012	belongs to the aldehyde dehydrogenase family
CGK93_10325	COG0460	homoserine dehydrogenase
CGK93_10330	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CGK93_10340	COG0697	spore germination
CGK93_10350	COG0583	DNA-binding transcription factor activity
CGK93_10365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CGK93_10380	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_10385	COG3250	beta-galactosidase activity
CGK93_10405	COG0444	Belongs to the ABC transporter superfamily
CGK93_10425	COG1609	Transcriptional regulator
CGK93_10430	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_10445	COG2814	Major facilitator Superfamily
CGK93_10455	COG3507	Belongs to the glycosyl hydrolase 43 family
CGK93_10465	COG2072	flavoprotein involved in K transport
CGK93_10490	COG3485	protocatechuate 3,4-dioxygenase
CGK93_10495	COG4638	Rieske (2fe-2S)
CGK93_10500	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CGK93_10520	COG0583	DNA-binding transcription factor activity
CGK93_10525	COG2814	Major facilitator Superfamily
CGK93_10575	COG0154	amidase activity
CGK93_10595	COG1228	amidohydrolase
CGK93_10600	COG1228	amidohydrolase
CGK93_10610	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_10615	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CGK93_10640	COG0402	S-adenosylhomocysteine deaminase activity
CGK93_10650	COG3534	alpha-L-arabinofuranosidase
CGK93_10655	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CGK93_10660	COG2186	Transcriptional regulator
CGK93_10665	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CGK93_10680	COG1175	transmembrane transport
CGK93_10695	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_10710	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_10740	COG1957	nucleoside hydrolase
CGK93_10750	COG1609	Transcriptional regulator
CGK93_10760	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CGK93_10770	COG1609	Transcriptional regulator
CGK93_10785	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_10790	COG4948	Mandelate Racemase Muconate Lactonizing
CGK93_10820	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CGK93_10855	COG0395	ABC-type sugar transport system, permease component
CGK93_10860	COG1609	Transcriptional regulator
CGK93_10865	COG3534	alpha-L-arabinofuranosidase
CGK93_10955	COG1401	restriction endodeoxyribonuclease activity
CGK93_10975	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CGK93_10980	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CGK93_11000	COG0667	Aldo Keto reductase
CGK93_11030	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CGK93_11035	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CGK93_11045	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_11050	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_11065	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CGK93_11095	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CGK93_11105	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CGK93_11105	COG0446	pyridine nucleotide-disulphide oxidoreductase
CGK93_11200	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CGK93_11205	COG0861	Integral membrane protein TerC family
CGK93_11285	COG0628	permease
CGK93_11325	COG0395	ABC-type sugar transport system, permease component
CGK93_11330	COG1063	alcohol dehydrogenase
CGK93_11370	COG0656	L-ascorbic acid biosynthetic process
CGK93_11395	COG1063	alcohol dehydrogenase
CGK93_11405	COG5002	protein histidine kinase activity
CGK93_11420	COG0673	inositol 2-dehydrogenase activity
CGK93_11430	COG1172	Belongs to the binding-protein-dependent transport system permease family
CGK93_11435	COG1879	ABC-type sugar transport system periplasmic component
CGK93_11440	COG1082	Xylose isomerase domain protein TIM barrel
CGK93_11445	COG1082	Xylose isomerase domain protein TIM barrel
CGK93_11450	COG1129	ABC transporter
CGK93_11485	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CGK93_11490	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CGK93_11495	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CGK93_11520	COG3842	ATPase activity
CGK93_11555	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CGK93_11565	COG0436	Aminotransferase
CGK93_11605	COG1012	belongs to the aldehyde dehydrogenase family
CGK93_11615	COG0464	growth
CGK93_11620	COG2354	Protein conserved in bacteria
CGK93_11630	COG0747	negative chemotaxis
CGK93_11635	COG0601	transmembrane transport
CGK93_11640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CGK93_11645	COG0444	Belongs to the ABC transporter superfamily
CGK93_11650	COG4608	Belongs to the ABC transporter superfamily
CGK93_11670	COG2828	Protein conserved in bacteria
CGK93_11690	COG0747	negative chemotaxis
CGK93_11715	COG0531	amino acid
CGK93_11735	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_11740	COG0475	glutathione-regulated potassium exporter activity
CGK93_11755	COG0028	Belongs to the TPP enzyme family
CGK93_11775	COG1120	ATPase activity
CGK93_11780	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CGK93_11800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CGK93_11825	COG0179	Fumarylacetoacetate (FAA) hydrolase
CGK93_11845	COG0179	Fumarylacetoacetate (FAA) hydrolase
CGK93_11855	COG2814	Major facilitator Superfamily
CGK93_11860	COG0583	DNA-binding transcription factor activity
CGK93_11870	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CGK93_11885	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CGK93_11920	COG1643	Atp-dependent helicase
CGK93_11925	COG1228	amidohydrolase
CGK93_11965	COG0009	L-threonylcarbamoyladenylate synthase
CGK93_11975	COG1131	(ABC) transporter
CGK93_12025	COG3483	tryptophan 2,3-dioxygenase activity
CGK93_12060	COG2050	protein possibly involved in aromatic compounds catabolism
CGK93_12070	COG4552	Acetyltransferase involved in intracellular survival and related
CGK93_12080	COG0539	negative regulation of cytoplasmic translation
CGK93_12085	COG1739	Uncharacterized protein family UPF0029
CGK93_12090	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CGK93_12090	COG0237	dephospho-CoA kinase activity
CGK93_12095	COG0556	nucleotide-excision repair
CGK93_12100	COG0861	Integral membrane protein TerC family
CGK93_12105	COG0477	Major facilitator Superfamily
CGK93_12120	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CGK93_12130	COG4106	trans-aconitate 2-methyltransferase activity
CGK93_12145	COG0546	phosphoglycolate phosphatase activity
CGK93_12155	COG0322	excinuclease ABC activity
CGK93_12160	COG1660	Displays ATPase and GTPase activities
CGK93_12170	COG1481	regulation of sporulation
CGK93_12175	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CGK93_12180	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CGK93_12185	COG0126	phosphoglycerate kinase activity
CGK93_12190	COG0149	triose-phosphate isomerase activity
CGK93_12195	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CGK93_12205	COG0363	glucosamine-6-phosphate deaminase activity
CGK93_12220	COG0166	Belongs to the GPI family
CGK93_12225	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CGK93_12235	COG0109	protoheme IX farnesyltransferase activity
CGK93_12260	COG0577	efflux transmembrane transporter activity
CGK93_12260	COG1136	(ABC) transporter
CGK93_12265	COG1612	heme a metabolic process
CGK93_12270	COG0842	Transport permease protein
CGK93_12275	COG1131	(ABC) transporter
CGK93_12290	COG0719	Fe-S assembly protein
CGK93_12300	COG0396	ATPase activity
CGK93_12305	COG2151	metal-sulfur cluster biosynthetic enzyme
CGK93_12315	COG0318	PFAM AMP-dependent synthetase and ligase
CGK93_12330	COG1122	ATPase activity
CGK93_12335	COG1268	BioY protein
CGK93_12340	COG0488	(ABC) transporter
CGK93_12365	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_12370	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_12375	COG1129	ABC transporter
CGK93_12385	COG0560	Phosphoserine phosphatase
CGK93_12385	COG3830	Belongs to the UPF0237 family
CGK93_12390	COG1119	ATPase activity
CGK93_12405	COG0254	rRNA binding
CGK93_12420	COG2855	membrane
CGK93_12445	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CGK93_12450	COG0297	glycogen (starch) synthase activity
CGK93_12465	COG0183	Belongs to the thiolase family
CGK93_12470	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_12485	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CGK93_12505	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CGK93_12520	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CGK93_12530	COG1215	transferase activity, transferring glycosyl groups
CGK93_12575	COG1088	dTDP-glucose 4,6-dehydratase activity
CGK93_12580	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CGK93_12585	COG0667	Aldo Keto reductase
CGK93_12590	COG1968	undecaprenyl-diphosphatase activity
CGK93_12595	COG0215	cysteine-tRNA ligase activity
CGK93_12605	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CGK93_12610	COG1994	Peptidase M50
CGK93_12610	COG0517	IMP dehydrogenase activity
CGK93_12620	COG1222	aaa ATPase
CGK93_12625	COG4122	O-methyltransferase activity
CGK93_12635	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CGK93_12640	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CGK93_12645	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CGK93_12650	COG0545	Peptidyl-prolyl cis-trans isomerase
CGK93_12670	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CGK93_12675	COG0805	protein transport
CGK93_12680	COG4581	dead DEAH box helicase
CGK93_12685	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CGK93_12690	COG1216	Glycosyl transferase, family 2
CGK93_12715	COG0823	Involved in the tonB-independent uptake of proteins
CGK93_12715	COG4946	Tricorn protease homolog
CGK93_12715	COG1506	peptidase
CGK93_12720	COG0242	peptide deformylase activity
CGK93_12740	COG3424	synthase
CGK93_12745	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CGK93_12765	COG3718	enzyme involved in inositol metabolism
CGK93_12770	COG0673	inositol 2-dehydrogenase activity
CGK93_12775	COG0673	inositol 2-dehydrogenase activity
CGK93_12780	COG0673	inositol 2-dehydrogenase activity
CGK93_12790	COG1172	Belongs to the binding-protein-dependent transport system permease family
CGK93_12820	COG2814	Major facilitator Superfamily
CGK93_12825	COG1082	Xylose isomerase domain protein TIM barrel
CGK93_12830	COG0673	inositol 2-dehydrogenase activity
CGK93_12845	COG3962	Belongs to the TPP enzyme family
CGK93_12855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CGK93_12860	COG1942	4-Oxalocrotonate Tautomerase
CGK93_12890	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CGK93_12895	COG1845	cytochrome c oxidase, subunit III
CGK93_12900	COG2010	Cytochrome c
CGK93_12905	COG0723	plastoquinol--plastocyanin reductase activity
CGK93_12910	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CGK93_12915	COG2188	Transcriptional regulator
CGK93_12920	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CGK93_12930	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CGK93_12935	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CGK93_12955	COG0167	dihydroorotate dehydrogenase activity
CGK93_12970	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CGK93_12975	COG1381	Involved in DNA repair and RecF pathway recombination
CGK93_12980	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CGK93_12985	COG3590	peptidase
CGK93_12990	COG1316	TRANSCRIPTIONal
CGK93_12995	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CGK93_13005	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CGK93_13020	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CGK93_13025	COG0484	heat shock protein binding
CGK93_13030	COG1420	regulation of RNA biosynthetic process
CGK93_13050	COG0481	GTPase activity
CGK93_13060	COG0268	Binds directly to 16S ribosomal RNA
CGK93_13080	COG1307	EDD domain protein, DegV family
CGK93_13085	COG0495	leucyl-tRNA aminoacylation
CGK93_13090	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CGK93_13095	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CGK93_13100	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CGK93_13105	COG2390	Transcriptional regulator
CGK93_13110	COG0656	L-ascorbic acid biosynthetic process
CGK93_13120	COG0438	transferase activity, transferring glycosyl groups
CGK93_13130	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CGK93_13140	COG1758	RNA polymerase activity
CGK93_13145	COG0194	GDP metabolic process
CGK93_13155	COG0284	orotidine-5'-phosphate decarboxylase activity
CGK93_13160	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CGK93_13165	COG0505	Belongs to the CarA family
CGK93_13175	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CGK93_13180	COG0540	Belongs to the ATCase OTCase family
CGK93_13185	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CGK93_13195	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CGK93_13200	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CGK93_13210	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CGK93_13215	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CGK93_13220	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CGK93_13225	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CGK93_13235	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CGK93_13240	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CGK93_13255	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CGK93_13275	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CGK93_13280	COG0124	histidyl-tRNA synthetase
CGK93_13290	COG1196	nuclear chromosome segregation
CGK93_13300	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CGK93_13305	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CGK93_13310	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CGK93_13320	COG2255	four-way junction helicase activity
CGK93_13325	COG0632	four-way junction helicase activity
CGK93_13330	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CGK93_13335	COG0217	transcriptional regulatory protein
CGK93_13340	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CGK93_13360	COG0339	signal peptide processing
CGK93_13365	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CGK93_13380	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CGK93_13385	COG0587	DNA-directed DNA polymerase activity
CGK93_13410	COG2135	peptidase activity
CGK93_13425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CGK93_13480	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CGK93_13485	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CGK93_13490	COG1780	Probably involved in ribonucleotide reductase function
CGK93_13500	COG0583	DNA-binding transcription factor activity
CGK93_13535	COG0714	Associated with various cellular activities
CGK93_13555	COG1653	transport
CGK93_13560	COG1940	carbohydrate kinase activity
CGK93_13560	COG1846	Transcriptional regulator
CGK93_13565	COG2813	Specifically methylates the guanine in position
CGK93_13590	COG0799	negative regulation of ribosome biogenesis
CGK93_13600	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CGK93_13610	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CGK93_13615	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CGK93_13620	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CGK93_13625	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CGK93_13630	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CGK93_13635	COG0351	phosphomethylpyrimidine kinase
CGK93_13635	COG0352	thiamine-phosphate diphosphorylase activity
CGK93_13635	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CGK93_13640	COG1530	ribonuclease E activity
CGK93_13650	COG0105	UTP biosynthetic process
CGK93_13660	COG0285	dihydrofolate synthase activity
CGK93_13665	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CGK93_13680	COG0525	valine-tRNA ligase activity
CGK93_13685	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CGK93_13690	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CGK93_13695	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CGK93_13700	COG0740	serine-type endopeptidase activity
CGK93_13705	COG0740	serine-type endopeptidase activity
CGK93_13710	COG0544	peptidyl-prolyl cis-trans isomerase activity
CGK93_13755	COG0668	transmembrane transport
CGK93_13770	COG1946	Acyl-CoA thioesterase
CGK93_13830	COG0242	peptide deformylase activity
CGK93_13860	COG3022	response to hydroperoxide
CGK93_13875	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CGK93_13885	COG1045	serine acetyltransferase
CGK93_13890	COG0300	oxidoreductase activity
CGK93_13895	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CGK93_13905	COG1063	alcohol dehydrogenase
CGK93_13910	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_13920	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CGK93_13930	COG0477	Major facilitator Superfamily
CGK93_14055	COG0305	Participates in initiation and elongation during chromosome replication
CGK93_14060	COG0305	Participates in initiation and elongation during chromosome replication
CGK93_14310	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CGK93_14325	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CGK93_14330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CGK93_14345	COG4974	Belongs to the 'phage' integrase family
CGK93_14355	COG0606	chelatase, subunit chli
CGK93_14360	COG0792	nuclease activity
CGK93_14370	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CGK93_14380	COG0681	Belongs to the peptidase S26 family
CGK93_14385	COG0335	large ribosomal subunit rRNA binding
CGK93_14390	COG0336	Belongs to the RNA methyltransferase TrmD family
CGK93_14395	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CGK93_14400	COG1837	Belongs to the UPF0109 family
CGK93_14405	COG0228	four-way junction DNA binding
CGK93_14415	COG2514	catechol 2,3-dioxygenase activity
CGK93_14425	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CGK93_14440	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CGK93_14455	COG2814	Major facilitator Superfamily
CGK93_14490	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CGK93_14495	COG0571	ribonuclease III activity
CGK93_14500	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CGK93_14510	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CGK93_14525	COG0742	ribosomal rna small subunit methyltransferase
CGK93_14550	COG1181	Belongs to the D-alanine--D-alanine ligase family
CGK93_14555	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CGK93_14565	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CGK93_14570	COG0066	3-isopropylmalate dehydratase activity
CGK93_14575	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CGK93_14580	COG1414	Transcriptional regulator
CGK93_14625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CGK93_14630	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CGK93_14635	COG0473	3-isopropylmalate dehydrogenase activity
CGK93_14640	COG4585	Histidine kinase
CGK93_14645	COG2197	response regulator
CGK93_14650	COG0577	efflux transmembrane transporter activity
CGK93_14650	COG1136	(ABC) transporter
CGK93_14660	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CGK93_14665	COG1136	(ABC) transporter
CGK93_14665	COG0577	efflux transmembrane transporter activity
CGK93_14675	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CGK93_14680	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CGK93_14685	COG0440	acetolactate synthase activity
CGK93_14695	COG0129	dihydroxy-acid dehydratase activity
CGK93_14705	COG0088	Forms part of the polypeptide exit tunnel
CGK93_14710	COG2133	pyrroloquinoline quinone binding
CGK93_14745	COG0579	oxidoreductase
CGK93_14750	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CGK93_14755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CGK93_14765	COG1305	Transglutaminase-like
CGK93_14790	COG0179	Fumarylacetoacetate (FAA) hydrolase
CGK93_14800	COG1104	cysteine desulfurase activity
CGK93_14815	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CGK93_14825	COG1522	sequence-specific DNA binding
CGK93_14830	COG1113	amino acid transport
CGK93_14840	COG0022	dehydrogenase e1 component
CGK93_14845	COG0508	dehydrogenase complex catalyzes the overall conversion of
CGK93_14865	COG0477	Major facilitator Superfamily
CGK93_14870	COG1414	Transcriptional regulator
CGK93_14880	COG0531	amino acid
CGK93_14895	COG0419	ATPase involved in DNA repair
CGK93_14900	COG0420	3'-5' exonuclease activity
CGK93_14915	COG2149	membrane
CGK93_14940	COG1131	(ABC) transporter
CGK93_14955	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CGK93_14960	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CGK93_14965	COG1234	tRNA 3'-trailer cleavage
CGK93_14970	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CGK93_14980	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CGK93_14990	COG1335	isochorismatase
CGK93_15005	COG0363	glucosamine-6-phosphate deaminase activity
CGK93_15020	COG1902	pentaerythritol trinitrate reductase activity
CGK93_15050	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
CGK93_15055	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CGK93_15065	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CGK93_15070	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CGK93_15080	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CGK93_15085	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CGK93_15090	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CGK93_15095	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CGK93_15100	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CGK93_15105	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CGK93_15110	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CGK93_15115	COG0356	it plays a direct role in the translocation of protons across the membrane
CGK93_15135	COG1216	Glycosyl transferase, family 2
CGK93_15150	COG2890	protein-(glutamine-N5) methyltransferase activity
CGK93_15155	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CGK93_15165	COG0083	homoserine kinase activity
CGK93_15170	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CGK93_15175	COG0460	homoserine dehydrogenase
CGK93_15180	COG0019	diaminopimelate decarboxylase activity
CGK93_15185	COG0018	arginyl-trna synthetase
CGK93_15200	COG0543	2 iron, 2 sulfur cluster binding
CGK93_15200	COG0633	Ferredoxin
CGK93_15230	COG1643	Atp-dependent helicase
CGK93_15235	COG0537	adenosine 5'-monophosphoramidase activity
CGK93_15240	COG1064	alcohol dehydrogenase
CGK93_15265	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CGK93_15270	COG1121	(ABC) transporter
CGK93_15275	COG0803	Belongs to the bacterial solute-binding protein 9 family
CGK93_15285	COG1253	flavin adenine dinucleotide binding
CGK93_15290	COG0567	Dehydrogenase, E1 component
CGK93_15290	COG0508	dehydrogenase complex catalyzes the overall conversion of
CGK93_15320	COG1595	DNA-templated transcription, initiation
CGK93_15330	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CGK93_15340	COG0483	inositol monophosphate 1-phosphatase activity
CGK93_15345	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CGK93_15370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CGK93_15380	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CGK93_15385	COG0739	heme binding
CGK93_15390	COG2177	Part of the ABC transporter FtsEX involved in
CGK93_15395	COG2884	Cell division ATP-binding protein ftsE
CGK93_15400	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CGK93_15510	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CGK93_15540	COG2902	Dehydrogenase
CGK93_15575	COG0653	protein targeting
CGK93_15580	COG3214	Protein conserved in bacteria
CGK93_15585	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CGK93_15595	COG5401	PFAM Sporulation and spore germination
CGK93_15600	COG5002	protein histidine kinase activity
CGK93_15625	COG0714	Associated with various cellular activities
CGK93_15655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CGK93_15660	COG0601	transmembrane transport
CGK93_15680	COG0482	sulfurtransferase activity
CGK93_15695	COG1597	lipid kinase activity
CGK93_15700	COG0484	heat shock protein binding
CGK93_15705	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CGK93_15725	COG3265	gluconokinase activity
CGK93_15730	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CGK93_15735	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CGK93_15740	COG2086	electron transfer activity
CGK93_15745	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CGK93_15760	COG1842	Phage shock protein A
CGK93_15765	COG2188	Transcriptional regulator
CGK93_15780	COG1615	UPF0182 protein
CGK93_15805	COG2816	NAD+ diphosphatase activity
CGK93_15835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CGK93_15840	COG0765	amino acid transport
CGK93_15845	COG1126	abc transporter atp-binding protein
CGK93_15850	COG1472	Belongs to the glycosyl hydrolase 3 family
CGK93_15855	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CGK93_15865	COG0113	porphobilinogen synthase activity
CGK93_15875	COG0181	hydroxymethylbilane synthase activity
CGK93_15895	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CGK93_15900	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CGK93_15910	COG1309	transcriptional regulator
CGK93_15930	COG2022	thiamine diphosphate biosynthetic process
CGK93_15945	COG0352	thiamine-phosphate diphosphorylase activity
CGK93_15955	COG2314	TM2 domain
CGK93_15965	COG0513	Belongs to the DEAD box helicase family
CGK93_15975	COG2095	MarC family integral membrane protein
CGK93_15995	COG2239	Acts as a magnesium transporter
CGK93_16010	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CGK93_16020	COG1595	DNA-templated transcription, initiation
CGK93_16025	COG4122	O-methyltransferase activity
CGK93_16050	COG1126	abc transporter atp-binding protein
CGK93_16055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CGK93_16060	COG0765	amino acid transport
CGK93_16065	COG0765	amino acid transport
CGK93_16070	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CGK93_16075	COG2171	N-acyltransferase activity
CGK93_16090	COG3226	Transcriptional regulator
CGK93_16095	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CGK93_16140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CGK93_16145	COG0601	transmembrane transport
CGK93_16150	COG0747	negative chemotaxis
CGK93_16155	COG0012	GTP binding
CGK93_16160	COG1322	Protein conserved in bacteria
CGK93_16165	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CGK93_16175	COG1570	exodeoxyribonuclease VII activity
CGK93_16180	COG1722	exodeoxyribonuclease VII activity
CGK93_16185	COG2326	polyphosphate kinase activity
CGK93_16215	COG1162	GTPase activity
CGK93_16235	COG2971	BadF BadG BcrA BcrD
CGK93_16240	COG2070	2-Nitropropane dioxygenase
CGK93_16245	COG0583	DNA-binding transcription factor activity
CGK93_16250	COG2814	Major facilitator Superfamily
CGK93_16255	COG3548	integral membrane protein
CGK93_16280	COG0598	Magnesium transport protein CorA
CGK93_16290	COG1528	Iron-storage protein
CGK93_16295	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CGK93_16300	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CGK93_16310	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CGK93_16340	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CGK93_16345	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CGK93_16365	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CGK93_16365	COG0519	Catalyzes the synthesis of GMP from XMP
CGK93_16385	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CGK93_16425	COG2072	flavoprotein involved in K transport
CGK93_16440	COG0459	protein refolding
CGK93_16445	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CGK93_16460	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CGK93_16465	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CGK93_16475	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CGK93_16480	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CGK93_16485	COG0456	acetyltransferase
CGK93_16495	COG0802	atpase or kinase
CGK93_16500	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CGK93_16510	COG1486	melibiose metabolic process
CGK93_16520	COG0438	transferase activity, transferring glycosyl groups
CGK93_16525	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CGK93_16535	COG0667	Aldo Keto reductase
CGK93_16560	COG0736	holo-[acyl-carrier-protein] synthase activity
CGK93_16565	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CGK93_16580	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CGK93_16585	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CGK93_16590	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CGK93_16620	COG0455	bacterial-type flagellum organization
CGK93_16640	COG0101	tRNA pseudouridine synthase activity
CGK93_16645	COG0203	ribosomal protein L17
CGK93_16650	COG0202	RNA polymerase activity
CGK93_16655	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CGK93_16660	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CGK93_16665	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CGK93_16670	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CGK93_16705	COG0318	PFAM AMP-dependent synthetase and ligase
CGK93_16710	COG2124	cytochrome p450
CGK93_16715	COG1215	transferase activity, transferring glycosyl groups
CGK93_16720	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CGK93_16725	COG0563	adenylate kinase activity
CGK93_16735	COG0200	Binds to the 23S rRNA
CGK93_16740	COG1841	ribosomal large subunit assembly
CGK93_16745	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CGK93_16755	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CGK93_16760	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CGK93_16765	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CGK93_16770	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CGK93_16775	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CGK93_16780	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CGK93_16785	COG0255	Belongs to the universal ribosomal protein uL29 family
CGK93_16790	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CGK93_16795	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CGK93_16800	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CGK93_16805	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CGK93_16810	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CGK93_16815	COG0089	rRNA binding
CGK93_16820	COG0088	Forms part of the polypeptide exit tunnel
CGK93_16825	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CGK93_16830	COG0051	transcription antitermination factor activity, RNA binding
CGK93_16845	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CGK93_16850	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CGK93_16855	COG0049	tRNA binding
CGK93_16860	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CGK93_16865	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CGK93_16870	COG0085	RNA polymerase activity
CGK93_16875	COG0183	Belongs to the thiolase family
CGK93_16880	COG0442	prolyl-tRNA aminoacylation
CGK93_16885	COG0222	ribosome binding
CGK93_16890	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CGK93_16905	COG0081	regulation of translation
CGK93_16910	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CGK93_16920	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CGK93_16930	COG0436	Aminotransferase
CGK93_16935	COG2197	response regulator
CGK93_16985	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CGK93_16995	COG3485	protocatechuate 3,4-dioxygenase
CGK93_17005	COG0745	RESPONSE REGULATOR receiver
CGK93_17010	COG0456	acetyltransferase
CGK93_17015	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CGK93_17035	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CGK93_17040	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CGK93_17050	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CGK93_17080	COG2030	dehydratase
CGK93_17110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CGK93_17120	COG4989	oxidoreductase activity
CGK93_17125	COG0366	Alpha amylase catalytic
CGK93_17145	COG1940	carbohydrate kinase activity
CGK93_17170	COG1376	ErfK ybiS ycfS ynhG family protein
CGK93_17200	COG0754	glutathionylspermidine amidase activity
CGK93_17210	COG5650	phosphatidylinositol metabolic process
CGK93_17225	COG1653	transport
CGK93_17265	COG5650	phosphatidylinositol metabolic process
CGK93_17300	COG0318	PFAM AMP-dependent synthetase and ligase
CGK93_17310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CGK93_17315	COG5479	isomerase activity
CGK93_17315	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CGK93_17320	COG1309	transcriptional regulator
CGK93_17325	COG1131	(ABC) transporter
CGK93_17345	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CGK93_17360	COG1666	GTP binding
CGK93_17365	COG0501	Belongs to the peptidase M48B family
CGK93_17395	COG0531	amino acid
CGK93_17440	COG1012	belongs to the aldehyde dehydrogenase family
CGK93_17445	COG2508	Transcriptional regulator
CGK93_17450	COG2807	transmembrane transport
CGK93_17455	COG2186	Transcriptional regulator
CGK93_17460	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CGK93_17460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CGK93_17480	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CGK93_17480	COG1648	precorrin-2 dehydrogenase activity
CGK93_17490	COG2066	Belongs to the glutaminase family
CGK93_17505	COG1982	Orn Lys Arg decarboxylase major
CGK93_17510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CGK93_17545	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CGK93_17560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CGK93_17565	COG1116	anion transmembrane transporter activity
CGK93_17575	COG2040	homocysteine
CGK93_17595	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CGK93_17605	COG2860	membrane
CGK93_17630	COG2226	methyltransferase
CGK93_17635	COG1169	isochorismate synthase
CGK93_17640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CGK93_17645	COG0765	amino acid transport
CGK93_17660	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CGK93_17670	COG4948	Mandelate Racemase Muconate Lactonizing
CGK93_17690	COG1621	beta-fructofuranosidase activity
CGK93_17695	COG0395	ABC-type sugar transport system, permease component
CGK93_17700	COG1175	transmembrane transport
CGK93_17755	COG1404	Belongs to the peptidase S8 family
CGK93_17765	COG0662	Cupin 2, conserved barrel domain protein
CGK93_17800	COG0508	dehydrogenase complex catalyzes the overall conversion of
CGK93_17805	COG0022	dehydrogenase e1 component
CGK93_17830	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CGK93_17855	COG1215	transferase activity, transferring glycosyl groups
CGK93_17865	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CGK93_17875	COG1134	teichoic acid transport
CGK93_17885	COG0438	transferase activity, transferring glycosyl groups
CGK93_17905	COG1316	TRANSCRIPTIONal
CGK93_17930	COG0596	Alpha beta hydrolase
CGK93_17940	COG4585	Histidine kinase
CGK93_17970	COG3655	Transcriptional regulator
CGK93_18000	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CGK93_18010	COG1597	lipid kinase activity
CGK93_18015	COG1024	Enoyl-CoA hydratase
CGK93_18020	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CGK93_18025	COG2151	metal-sulfur cluster biosynthetic enzyme
CGK93_18030	COG3396	Phenylacetate-CoA oxygenase
CGK93_18035	COG3460	Phenylacetate-CoA oxygenase
CGK93_18040	COG3396	Phenylacetate-CoA oxygenase
CGK93_18050	COG1316	TRANSCRIPTIONal
CGK93_18055	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CGK93_18095	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CGK93_18110	COG0489	protein tyrosine kinase activity
CGK93_18115	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CGK93_18130	COG3706	GGDEF domain
CGK93_18170	COG0438	transferase activity, transferring glycosyl groups
CGK93_18185	COG2226	methyltransferase
CGK93_18195	COG5002	protein histidine kinase activity
CGK93_18215	COG2050	protein possibly involved in aromatic compounds catabolism
CGK93_18220	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CGK93_18230	COG2030	dehydratase
CGK93_18230	COG1012	belongs to the aldehyde dehydrogenase family
CGK93_18235	COG1216	Glycosyl transferase, family 2
CGK93_18245	COG2755	lipolytic protein G-D-S-L family
CGK93_18255	COG1250	3-hydroxyacyl-CoA dehydrogenase
CGK93_18260	COG1024	Enoyl-CoA hydratase
CGK93_18265	COG0183	Belongs to the thiolase family
CGK93_18285	COG1022	Amp-dependent synthetase and ligase
CGK93_18310	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CGK93_18320	COG0488	(ABC) transporter
CGK93_18335	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CGK93_18340	COG1121	(ABC) transporter
CGK93_18345	COG0803	Belongs to the bacterial solute-binding protein 9 family
CGK93_18350	COG1266	CAAX protease self-immunity
CGK93_18360	COG0395	ABC-type sugar transport system, permease component
CGK93_18365	COG1175	transmembrane transport
CGK93_18380	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CGK93_18430	COG0443	Heat shock 70 kDa protein
CGK93_18435	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CGK93_18440	COG1333	cytochrome c biogenesis protein
CGK93_18445	COG0785	Cytochrome C biogenesis protein
CGK93_18455	COG0406	alpha-ribazole phosphatase activity
CGK93_18480	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CGK93_18490	COG0560	Phosphoserine phosphatase
CGK93_18510	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CGK93_18515	COG3458	cephalosporin-C deacetylase activity
CGK93_18525	COG2755	lipolytic protein G-D-S-L family
CGK93_18530	COG0395	ABC-type sugar transport system, permease component
CGK93_18535	COG4209	transmembrane transport
CGK93_18540	COG1653	transport
CGK93_18545	COG5578	integral membrane protein
CGK93_18565	COG2814	Major facilitator Superfamily
CGK93_18575	COG0395	ABC-type sugar transport system, permease component
CGK93_18580	COG1175	transmembrane transport
CGK93_18600	COG0395	ABC-type sugar transport system, permease component
CGK93_18605	COG1175	transmembrane transport
CGK93_18630	COG4948	Mandelate Racemase Muconate Lactonizing
CGK93_18635	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CGK93_18645	COG0673	inositol 2-dehydrogenase activity
CGK93_18655	COG1802	Transcriptional regulator
CGK93_18665	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CGK93_18670	COG0640	Transcriptional regulator
CGK93_18675	COG0123	including yeast histone deacetylase and acetoin utilization protein
CGK93_18680	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CGK93_18685	COG0569	domain protein
CGK93_18690	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CGK93_18695	COG1082	Xylose isomerase domain protein TIM barrel
CGK93_18700	COG0248	Ppx GppA phosphatase
CGK93_18710	COG1754	DNA topoisomerase type I activity
CGK93_18710	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CGK93_18745	COG1205	dead DEAH box helicase
CGK93_18745	COG1111	helicase
CGK93_18850	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CGK93_18855	COG1349	DNA-binding transcription factor activity
CGK93_18870	COG1609	Transcriptional regulator
CGK93_18880	COG4209	transmembrane transport
CGK93_18885	COG0395	ABC-type sugar transport system, permease component
CGK93_18900	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CGK93_18930	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CGK93_18935	COG1408	metallophosphoesterase
CGK93_18940	COG1132	(ABC) transporter
CGK93_18945	COG1132	(ABC) transporter
CGK93_18965	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CGK93_18970	COG0151	Belongs to the GarS family
CGK93_18985	COG1301	dicarboxylic acid transport
CGK93_18995	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_19005	COG1953	Uracil, thiamine, allantoin
CGK93_19010	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CGK93_19030	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CGK93_19040	COG3608	succinylglutamate desuccinylase aspartoacylase
CGK93_19040	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CGK93_19045	COG2252	PERMEase
CGK93_19050	COG0590	tRNA wobble adenosine to inosine editing
CGK93_19085	COG2233	PERMEase
CGK93_19095	COG1414	Transcriptional regulator
CGK93_19115	COG3257	ureidoglycine aminohydrolase activity
CGK93_19135	COG2318	DinB family
CGK93_19145	COG4499	WXG100 protein secretion system (Wss), protein YukC
CGK93_19145	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CGK93_19165	COG0673	inositol 2-dehydrogenase activity
CGK93_19170	COG0477	Major facilitator Superfamily
CGK93_19175	COG1414	Transcriptional regulator
CGK93_19180	COG0583	DNA-binding transcription factor activity
CGK93_19190	COG1063	alcohol dehydrogenase
CGK93_19195	COG1053	succinate dehydrogenase
CGK93_19225	COG0659	secondary active sulfate transmembrane transporter activity
CGK93_19255	COG0563	adenylate kinase activity
CGK93_19280	COG0477	Major facilitator Superfamily
CGK93_19300	COG3401	FG-GAP repeat protein
CGK93_19365	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CGK93_19370	COG1733	regulation of RNA biosynthetic process
CGK93_19375	COG2267	carboxylic ester hydrolase activity
CGK93_19415	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CGK93_19420	COG1024	Enoyl-CoA hydratase
CGK93_19425	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CGK93_19480	COG1942	4-Oxalocrotonate Tautomerase
CGK93_19545	COG0405	Gamma-glutamyltransferase
CGK93_19590	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CGK93_19640	COG0673	inositol 2-dehydrogenase activity
CGK93_19655	COG1653	transport
CGK93_19660	COG1609	Transcriptional regulator
CGK93_19695	COG3093	addiction module antidote protein HigA
CGK93_19720	COG3622	Belongs to the hyi family
CGK93_19725	COG2084	Dehydrogenase
CGK93_19730	COG3960	tartronate-semialdehyde synthase activity
CGK93_19735	COG1929	Belongs to the glycerate kinase type-1 family
CGK93_19740	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CGK93_19745	COG0745	RESPONSE REGULATOR receiver
CGK93_19755	COG0745	RESPONSE REGULATOR receiver
CGK93_19765	COG1366	Belongs to the anti-sigma-factor antagonist family
CGK93_19795	COG2814	Major facilitator Superfamily
CGK93_19805	COG0671	phosphoesterase, PA-phosphatase related
CGK93_19830	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CGK93_19855	COG0542	response to heat
CGK93_19900	COG3304	Inner membrane component domain
CGK93_19910	COG0135	phosphoribosylanthranilate isomerase activity
CGK93_19920	COG2076	Multidrug Resistance protein
CGK93_19925	COG2076	Multidrug Resistance protein
CGK93_19930	COG0667	Aldo Keto reductase
CGK93_19975	COG0477	Major facilitator Superfamily
CGK93_19980	COG2807	transmembrane transport
CGK93_19985	COG0259	pyridoxamine-phosphate oxidase activity
CGK93_19990	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CGK93_20030	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CGK93_20040	COG2188	Transcriptional regulator
CGK93_20060	COG1609	Transcriptional regulator
CGK93_20070	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CGK93_20075	COG1653	transport
CGK93_20080	COG1175	transmembrane transport
CGK93_20085	COG0395	ABC-type sugar transport system, permease component
CGK93_20105	COG0154	amidase activity
CGK93_20110	COG2957	Belongs to the agmatine deiminase family
CGK93_20140	COG0789	Transcriptional regulator
CGK93_20145	COG0484	heat shock protein binding
CGK93_20150	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CGK93_20155	COG0443	Heat shock 70 kDa protein
CGK93_20160	COG3739	integral membrane protein
CGK93_20215	COG1175	transmembrane transport
CGK93_20220	COG0395	ABC-type sugar transport system, permease component
CGK93_20230	COG1940	carbohydrate kinase activity
CGK93_20255	COG1609	Transcriptional regulator
CGK93_20265	COG1653	transport
CGK93_20280	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CGK93_20295	COG3540	Alkaline phosphatase
CGK93_20335	COG3226	Transcriptional regulator
CGK93_20340	COG1280	lysine exporter protein (LysE YggA)
CGK93_20370	COG2409	Drug exporters of the RND superfamily
CGK93_20380	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CGK93_20385	COG3795	YCII-related domain
CGK93_20390	COG4941	Belongs to the sigma-70 factor family
CGK93_20395	COG0667	Aldo Keto reductase
CGK93_20405	COG1280	lysine exporter protein (LysE YggA)
CGK93_20415	COG1609	Transcriptional regulator
CGK93_20420	COG1957	nucleoside hydrolase
CGK93_20425	COG0477	Major facilitator Superfamily
CGK93_20430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CGK93_20440	COG1309	transcriptional regulator
CGK93_20445	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CGK93_20455	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CGK93_20465	COG0833	amino acid
CGK93_20470	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CGK93_20480	COG2986	histidine ammonia-lyase
CGK93_20515	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CGK93_20520	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CGK93_20555	COG1122	ATPase activity
CGK93_20560	COG4721	ABC-type cobalt transport system, permease component
CGK93_20575	COG1320	monovalent cation:proton antiporter activity
CGK93_20580	COG2212	antiporter activity
CGK93_20595	COG1006	Multisubunit Na H antiporter MnhC subunit
CGK93_20600	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CGK93_20600	COG2111	Na H antiporter
CGK93_20615	COG0475	glutathione-regulated potassium exporter activity
CGK93_20625	COG0717	Belongs to the dCTP deaminase family
CGK93_20655	COG0686	Belongs to the AlaDH PNT family
CGK93_20665	COG0583	DNA-binding transcription factor activity
CGK93_20680	COG0657	acetylesterase activity
CGK93_20680	COG2755	lipolytic protein G-D-S-L family
CGK93_20685	COG1609	Transcriptional regulator
CGK93_20690	COG0673	inositol 2-dehydrogenase activity
CGK93_20735	COG2115	Belongs to the xylose isomerase family
CGK93_20740	COG1070	Carbohydrate kinase
CGK93_20745	COG1609	Transcriptional regulator
CGK93_20760	COG2160	L-arabinose isomerase activity
CGK93_20765	COG2017	converts alpha-aldose to the beta-anomer
CGK93_20790	COG3347	Dehydrogenase
CGK93_20790	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_20795	COG1070	Carbohydrate kinase
CGK93_20800	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CGK93_20835	COG3387	PFAM Glycoside hydrolase 15-related
CGK93_20840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CGK93_20845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CGK93_20850	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CGK93_20880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CGK93_20890	COG1126	abc transporter atp-binding protein
CGK93_20910	COG0433	COG0433 Predicted ATPase
CGK93_20925	COG3336	cytochrome c oxidase
CGK93_20930	COG0776	regulation of translation
CGK93_20985	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CGK93_20990	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CGK93_20995	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CGK93_21030	COG1120	ATPase activity
CGK93_21035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGK93_21040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGK93_21080	COG3012	SEC-C Motif Domain Protein
CGK93_21095	COG0667	Aldo Keto reductase
CGK93_21135	COG2186	Transcriptional regulator
CGK93_21145	COG1027	Aspartate ammonia-lyase
CGK93_21155	COG2186	Transcriptional regulator
CGK93_21160	COG3618	amidohydrolase
CGK93_21170	COG3254	rhamnose metabolic process
CGK93_21180	COG4948	Mandelate Racemase Muconate Lactonizing
CGK93_21190	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_21195	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CGK93_21210	COG4221	oxidoreductase activity
CGK93_21225	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CGK93_21250	COG0640	Transcriptional regulator
CGK93_21265	COG2197	response regulator
CGK93_21270	COG4585	Histidine kinase
CGK93_21280	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CGK93_21305	COG1760	l-serine dehydratase
CGK93_21320	COG0281	malic enzyme
CGK93_21325	COG1309	transcriptional regulator
CGK93_21365	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CGK93_21370	COG0477	Major facilitator Superfamily
CGK93_21375	COG2986	histidine ammonia-lyase
CGK93_21380	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CGK93_21410	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CGK93_21420	COG0477	Major facilitator Superfamily
CGK93_21425	COG2814	Major facilitator Superfamily
CGK93_21430	COG1846	Transcriptional regulator
CGK93_21465	COG1113	amino acid transport
CGK93_21470	COG4604	ABC transporter, ATP-binding protein
CGK93_21475	COG4605	iron ion homeostasis
CGK93_21480	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGK93_21490	COG0246	Mannitol dehydrogenase
CGK93_21495	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CGK93_21495	COG2213	PTS system mannitol-specific
CGK93_21505	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CGK93_21510	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CGK93_21540	COG1793	dna ligase
CGK93_21555	COG0686	Belongs to the AlaDH PNT family
CGK93_21570	COG0673	inositol 2-dehydrogenase activity
CGK93_21580	COG2161	toxin-antitoxin pair type II binding
CGK93_21605	COG1309	transcriptional regulator
CGK93_21640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CGK93_21655	COG0531	amino acid
CGK93_21670	COG0508	dehydrogenase complex catalyzes the overall conversion of
CGK93_21675	COG0022	dehydrogenase e1 component
CGK93_21685	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CGK93_21690	COG1950	PFAM Membrane protein of
CGK93_21705	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CGK93_21720	COG1607	acyl-coa hydrolase
CGK93_21740	COG3971	2-oxopent-4-enoate hydratase activity
CGK93_21755	COG1802	Transcriptional regulator
CGK93_21760	COG0179	Fumarylacetoacetate (FAA) hydrolase
CGK93_21780	COG2261	transglycosylase associated protein
CGK93_21790	COG2207	Transcriptional regulator
CGK93_21790	COG3708	Transcriptional regulator
CGK93_21795	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_21860	COG1609	Transcriptional regulator
CGK93_21875	COG0395	ABC-type sugar transport system, permease component
CGK93_21880	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CGK93_21925	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CGK93_21965	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_21975	COG2207	Transcriptional regulator
CGK93_21980	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CGK93_21990	COG4209	transmembrane transport
CGK93_21995	COG0395	ABC-type sugar transport system, permease component
CGK93_22030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CGK93_22035	COG0395	ABC-type sugar transport system, permease component
CGK93_22040	COG1175	transmembrane transport
CGK93_22065	COG2188	Transcriptional regulator
CGK93_22070	COG0673	inositol 2-dehydrogenase activity
CGK93_22095	COG0492	ferredoxin-NADP+ reductase activity
CGK93_22125	COG1053	succinate dehydrogenase
CGK93_22135	COG0800	Aldolase
CGK93_22140	COG1940	carbohydrate kinase activity
CGK93_22155	COG4214	carbohydrate transport
CGK93_22160	COG4213	ABC transporter substrate-binding protein
CGK93_22165	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_22175	COG2186	Transcriptional regulator
CGK93_22180	COG0673	inositol 2-dehydrogenase activity
CGK93_22195	COG0673	inositol 2-dehydrogenase activity
CGK93_22220	COG0395	ABC-type sugar transport system, permease component
CGK93_22225	COG4209	transmembrane transport
CGK93_22245	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CGK93_22295	COG1396	sequence-specific DNA binding
CGK93_22305	COG0604	alcohol dehydrogenase
CGK93_22315	COG3387	PFAM Glycoside hydrolase 15-related
CGK93_22325	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
CGK93_22330	COG0477	Major facilitator Superfamily
CGK93_22335	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CGK93_22340	COG1063	alcohol dehydrogenase
CGK93_22345	COG1028	Short-chain dehydrogenase reductase Sdr
CGK93_22350	COG0800	Aldolase
CGK93_22360	COG1414	Transcriptional regulator
CGK93_22380	COG1414	Transcriptional regulator
CGK93_22385	COG2814	Major facilitator Superfamily
CGK93_22420	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CGK93_22430	COG2909	trisaccharide binding
CGK93_22435	COG0471	metal ion transport
CGK93_22435	COG0490	domain, Protein
CGK93_22440	COG0477	Major facilitator Superfamily
CGK93_22445	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CGK93_22450	COG2261	transglycosylase associated protein
CGK93_22455	COG0515	serine threonine protein kinase
CGK93_22465	COG1846	Transcriptional regulator
CGK93_22495	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CGK93_22500	COG1760	l-serine dehydratase
CGK93_22505	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CGK93_22510	COG0509	glycine decarboxylation via glycine cleavage system
CGK93_22515	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CGK93_22520	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CGK93_22520	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CGK93_22525	COG1970	mechanosensitive ion channel activity
CGK93_22540	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CGK93_22545	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CGK93_22550	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CGK93_22575	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CGK93_22605	COG2814	Major facilitator Superfamily
CGK93_22630	COG0179	Fumarylacetoacetate (FAA) hydrolase
CGK93_22635	COG0251	oxidation-reduction process
CGK93_22645	COG1414	Transcriptional regulator
CGK93_22650	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CGK93_22660	COG0183	Belongs to the thiolase family
CGK93_22665	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CGK93_22685	COG3485	protocatechuate 3,4-dioxygenase
CGK93_22695	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CGK93_22700	COG1414	Transcriptional regulator
CGK93_22705	COG0477	Major facilitator Superfamily
CGK93_22720	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CGK93_22730	COG3706	GGDEF domain
CGK93_22740	COG0583	DNA-binding transcription factor activity
CGK93_22775	COG0463	Glycosyl transferase, family 2
CGK93_22800	COG0366	Alpha amylase catalytic
CGK93_22815	COG2326	polyphosphate kinase activity
CGK93_22835	COG1737	Transcriptional regulator
CGK93_22840	COG3876	Protein conserved in bacteria
CGK93_22845	COG1472	Belongs to the glycosyl hydrolase 3 family
CGK93_22885	COG1937	Protein conserved in bacteria
CGK93_22940	COG0534	Mate efflux family protein
CGK93_22955	COG2259	Doxx family
CGK93_22965	COG0574	Belongs to the PEP-utilizing enzyme family
CGK93_22965	COG3848	Pyruvate phosphate dikinase
CGK93_22975	COG1607	acyl-coa hydrolase
CGK93_22985	COG0745	RESPONSE REGULATOR receiver
CGK93_22990	COG0642	Histidine kinase
CGK93_22990	COG3850	Histidine kinase
CGK93_23005	COG0305	Participates in initiation and elongation during chromosome replication
CGK93_23050	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CGK93_23055	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CGK93_23095	COG1414	Transcriptional regulator
CGK93_23100	COG1131	(ABC) transporter
CGK93_23110	COG0384	phenazine biosynthesis protein PhzF
CGK93_23120	COG0359	binds to the 23S rRNA
CGK93_23125	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CGK93_23135	COG0360	Binds together with S18 to 16S ribosomal RNA
CGK93_23140	COG1742	UPF0060 membrane protein
CGK93_23155	COG1113	amino acid transport
CGK93_23160	COG1362	aminopeptidase activity
CGK93_23180	COG1414	Transcriptional regulator
CGK93_23195	COG0833	amino acid
CGK93_23205	COG2197	response regulator
CGK93_23210	COG4585	Histidine kinase
CGK93_23220	COG1131	(ABC) transporter
CGK93_23235	COG0738	Major facilitator superfamily
CGK93_23255	COG0768	penicillin binding
CGK93_23260	COG1501	Belongs to the glycosyl hydrolase 31 family
CGK93_23265	COG2197	response regulator
CGK93_23270	COG4585	Histidine kinase
CGK93_23280	COG1136	(ABC) transporter
CGK93_23285	COG1733	regulation of RNA biosynthetic process
CGK93_23290	COG2910	NAD(P)H-binding
CGK93_23305	COG0406	alpha-ribazole phosphatase activity
CGK93_23310	COG0617	tRNA 3'-terminal CCA addition
CGK93_23330	COG0492	ferredoxin-NADP+ reductase activity
CGK93_23335	COG3118	belongs to the thioredoxin family
CGK93_23350	COG1192	Involved in chromosome partitioning
CGK93_23355	COG0357	Ribosomal RNA small subunit methyltransferase G
CGK93_23365	COG0706	membrane insertase activity
CGK93_23370	COG0759	Could be involved in insertion of integral membrane proteins into the membrane