locus-tag	class	description
ARZXY2_100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ARZXY2_1004	COG2902	Dehydrogenase
ARZXY2_1008	COG1674	ftsk spoiiie
ARZXY2_1010	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ARZXY2_1014	COG1216	Glycosyl transferase, family 2
ARZXY2_102	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ARZXY2_103	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ARZXY2_1032	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ARZXY2_1033	COG2884	Cell division ATP-binding protein ftsE
ARZXY2_1034	COG2177	Part of the ABC transporter FtsEX involved in
ARZXY2_1035	COG0739	heme binding
ARZXY2_1036	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ARZXY2_104	COG0477	Major facilitator Superfamily
ARZXY2_1042	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ARZXY2_1043	COG0483	inositol monophosphate 1-phosphatase activity
ARZXY2_1045	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ARZXY2_1048	COG1595	DNA-templated transcription, initiation
ARZXY2_105	COG1957	nucleoside hydrolase
ARZXY2_1053	COG0567	Dehydrogenase, E1 component
ARZXY2_1053	COG0508	dehydrogenase complex catalyzes the overall conversion of
ARZXY2_1054	COG1253	flavin adenine dinucleotide binding
ARZXY2_1056	COG0803	Belongs to the bacterial solute-binding protein 9 family
ARZXY2_1057	COG1121	(ABC) transporter
ARZXY2_1058	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ARZXY2_106	COG1609	Transcriptional regulator
ARZXY2_1063	COG1064	alcohol dehydrogenase
ARZXY2_1064	COG0537	adenosine 5'-monophosphoramidase activity
ARZXY2_1065	COG1643	Atp-dependent helicase
ARZXY2_107	COG1280	lysine exporter protein (LysE YggA)
ARZXY2_1072	COG1017	nitric oxide dioxygenase activity
ARZXY2_1072	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ARZXY2_1076	COG0018	arginyl-trna synthetase
ARZXY2_1077	COG0019	diaminopimelate decarboxylase activity
ARZXY2_1078	COG0460	homoserine dehydrogenase
ARZXY2_1079	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ARZXY2_1080	COG0083	homoserine kinase activity
ARZXY2_1082	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ARZXY2_1083	COG2890	protein-(glutamine-N5) methyltransferase activity
ARZXY2_1084	COG0009	L-threonylcarbamoyladenylate synthase
ARZXY2_1087	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ARZXY2_1089	COG0356	it plays a direct role in the translocation of protons across the membrane
ARZXY2_1091	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ARZXY2_1092	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ARZXY2_1093	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ARZXY2_1094	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ARZXY2_1095	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ARZXY2_1096	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ARZXY2_1097	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ARZXY2_1099	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ARZXY2_110	COG0667	Aldo Keto reductase
ARZXY2_1100	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ARZXY2_1102	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ARZXY2_1103	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
ARZXY2_1109	COG1902	pentaerythritol trinitrate reductase activity
ARZXY2_111	COG4941	Belongs to the sigma-70 factor family
ARZXY2_1112	COG0363	glucosamine-6-phosphate deaminase activity
ARZXY2_1115	COG1335	isochorismatase
ARZXY2_1118	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ARZXY2_112	COG3795	YCII-related domain
ARZXY2_1120	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ARZXY2_1121	COG1234	tRNA 3'-trailer cleavage
ARZXY2_1122	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ARZXY2_1123	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ARZXY2_1126	COG1131	(ABC) transporter
ARZXY2_113	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ARZXY2_1131	COG2149	membrane
ARZXY2_1135	COG0419	ATPase involved in DNA repair
ARZXY2_1137	COG1414	Transcriptional regulator
ARZXY2_1138	COG0477	Major facilitator Superfamily
ARZXY2_1142	COG0508	dehydrogenase complex catalyzes the overall conversion of
ARZXY2_1143	COG0022	dehydrogenase e1 component
ARZXY2_1145	COG1113	amino acid transport
ARZXY2_1146	COG1522	sequence-specific DNA binding
ARZXY2_1148	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ARZXY2_1149	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ARZXY2_115	COG2409	Drug exporters of the RND superfamily
ARZXY2_1151	COG1104	cysteine desulfurase activity
ARZXY2_1154	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ARZXY2_1156	COG1305	Transglutaminase-like
ARZXY2_1157	COG1846	Transcriptional regulator
ARZXY2_1158	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ARZXY2_1159	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ARZXY2_1161	COG0579	oxidoreductase
ARZXY2_1162	COG0747	negative chemotaxis
ARZXY2_1168	COG2133	pyrroloquinoline quinone binding
ARZXY2_117	COG2026	Addiction module toxin, RelE StbE family
ARZXY2_1170	COG0129	dihydroxy-acid dehydratase activity
ARZXY2_1172	COG0440	acetolactate synthase activity
ARZXY2_1173	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ARZXY2_1174	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ARZXY2_1176	COG1136	(ABC) transporter
ARZXY2_1176	COG0577	efflux transmembrane transporter activity
ARZXY2_1179	COG1136	(ABC) transporter
ARZXY2_1179	COG0577	efflux transmembrane transporter activity
ARZXY2_118	COG2161	toxin-antitoxin pair type II binding
ARZXY2_1180	COG2197	response regulator
ARZXY2_1181	COG4585	Histidine kinase
ARZXY2_1182	COG0473	3-isopropylmalate dehydrogenase activity
ARZXY2_1183	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ARZXY2_1184	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ARZXY2_1186	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ARZXY2_1195	COG1414	Transcriptional regulator
ARZXY2_1196	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ARZXY2_1197	COG0066	3-isopropylmalate dehydratase activity
ARZXY2_1198	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ARZXY2_12	COG0433	COG0433 Predicted ATPase
ARZXY2_120	COG1280	lysine exporter protein (LysE YggA)
ARZXY2_1200	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ARZXY2_1201	COG1181	Belongs to the D-alanine--D-alanine ligase family
ARZXY2_1204	COG1461	Dihydroxyacetone kinase
ARZXY2_1206	COG0742	ribosomal rna small subunit methyltransferase
ARZXY2_1209	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ARZXY2_1211	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ARZXY2_1212	COG0571	ribonuclease III activity
ARZXY2_1213	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ARZXY2_1225	COG2963	transposase activity
ARZXY2_1232	COG0210	DNA helicase
ARZXY2_124	COG1064	alcohol dehydrogenase
ARZXY2_125	COG0436	Aminotransferase
ARZXY2_1255	COG2132	Multicopper oxidase
ARZXY2_1257	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ARZXY2_1258	COG2226	methyltransferase
ARZXY2_1260	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ARZXY2_1262	COG2132	Multicopper oxidase
ARZXY2_1264	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ARZXY2_1270	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ARZXY2_1273	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
ARZXY2_1277	COG1611	Belongs to the LOG family
ARZXY2_1283	COG1937	Protein conserved in bacteria
ARZXY2_1286	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ARZXY2_1321	COG0750	zinc metalloprotease
ARZXY2_1341	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
ARZXY2_1357	COG0500	methyltransferase
ARZXY2_1359	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_1373	COG0542	response to heat
ARZXY2_1375	COG1074	ATP-dependent DNA helicase activity
ARZXY2_138	COG3540	Alkaline phosphatase
ARZXY2_1390	COG0798	PFAM Bile acid sodium symporter
ARZXY2_1395	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ARZXY2_1397	COG0659	secondary active sulfate transmembrane transporter activity
ARZXY2_1398	COG0789	Transcriptional regulator
ARZXY2_140	COG0477	Major facilitator Superfamily
ARZXY2_1403	COG1793	dna ligase
ARZXY2_1404	COG4974	Belongs to the 'phage' integrase family
ARZXY2_1408	COG1793	dna ligase
ARZXY2_1416	COG0085	RNA polymerase activity
ARZXY2_1450	COG2814	Major facilitator Superfamily
ARZXY2_1453	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ARZXY2_1458	COG2514	catechol 2,3-dioxygenase activity
ARZXY2_146	COG3739	integral membrane protein
ARZXY2_1460	COG0228	four-way junction DNA binding
ARZXY2_1461	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ARZXY2_1462	COG0336	Belongs to the RNA methyltransferase TrmD family
ARZXY2_1463	COG0335	large ribosomal subunit rRNA binding
ARZXY2_1464	COG0681	Belongs to the peptidase S26 family
ARZXY2_1466	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ARZXY2_1468	COG0792	nuclease activity
ARZXY2_147	COG0443	Heat shock 70 kDa protein
ARZXY2_148	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ARZXY2_1488	COG0606	chelatase, subunit chli
ARZXY2_149	COG0484	heat shock protein binding
ARZXY2_1492	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ARZXY2_1493	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ARZXY2_1496	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ARZXY2_1498	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_1499	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ARZXY2_150	COG0789	Transcriptional regulator
ARZXY2_1500	COG2124	cytochrome p450
ARZXY2_1504	COG0512	Glutamine amidotransferase of anthranilate synthase
ARZXY2_1507	COG0686	Belongs to the AlaDH PNT family
ARZXY2_151	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ARZXY2_1510	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ARZXY2_1515	COG2149	membrane
ARZXY2_1519	COG2814	Major facilitator Superfamily
ARZXY2_152	COG1879	ABC-type sugar transport system periplasmic component
ARZXY2_1526	COG4974	Belongs to the 'phage' integrase family
ARZXY2_1529	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ARZXY2_153	COG1129	ABC transporter
ARZXY2_1530	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ARZXY2_1533	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ARZXY2_1539	COG2801	Transposase and inactivated derivatives
ARZXY2_1539	COG3415	Transposase
ARZXY2_154	COG1172	Belongs to the binding-protein-dependent transport system permease family
ARZXY2_1542	COG0477	Major facilitator Superfamily
ARZXY2_1545	COG2084	Dehydrogenase
ARZXY2_1546	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_1547	COG1063	alcohol dehydrogenase
ARZXY2_1549	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ARZXY2_155	COG1082	Xylose isomerase domain protein TIM barrel
ARZXY2_1550	COG1045	serine acetyltransferase
ARZXY2_1552	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ARZXY2_1553	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ARZXY2_1555	COG3022	response to hydroperoxide
ARZXY2_1560	COG0242	peptide deformylase activity
ARZXY2_157	COG1737	Transcriptional regulator
ARZXY2_1572	COG1946	Acyl-CoA thioesterase
ARZXY2_1575	COG0668	transmembrane transport
ARZXY2_158	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ARZXY2_1584	COG0544	peptidyl-prolyl cis-trans isomerase activity
ARZXY2_1586	COG0740	serine-type endopeptidase activity
ARZXY2_1587	COG0740	serine-type endopeptidase activity
ARZXY2_1588	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ARZXY2_1589	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ARZXY2_159	COG2140	Oxalate decarboxylase
ARZXY2_1590	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ARZXY2_1592	COG0525	valine-tRNA ligase activity
ARZXY2_1596	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ARZXY2_1597	COG0285	dihydrofolate synthase activity
ARZXY2_1599	COG0105	UTP biosynthetic process
ARZXY2_16	COG1126	abc transporter atp-binding protein
ARZXY2_1602	COG1530	ribonuclease E activity
ARZXY2_1603	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ARZXY2_1603	COG0352	thiamine-phosphate diphosphorylase activity
ARZXY2_1603	COG0351	phosphomethylpyrimidine kinase
ARZXY2_1604	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ARZXY2_1605	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ARZXY2_1606	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ARZXY2_1607	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ARZXY2_1608	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ARZXY2_161	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ARZXY2_1610	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ARZXY2_1613	COG0799	negative regulation of ribosome biogenesis
ARZXY2_1618	COG2813	Specifically methylates the guanine in position
ARZXY2_1619	COG1940	carbohydrate kinase activity
ARZXY2_1619	COG1846	Transcriptional regulator
ARZXY2_162	COG1063	alcohol dehydrogenase
ARZXY2_1621	COG0714	Associated with various cellular activities
ARZXY2_1629	COG0583	DNA-binding transcription factor activity
ARZXY2_163	COG1063	alcohol dehydrogenase
ARZXY2_1631	COG1780	Probably involved in ribonucleotide reductase function
ARZXY2_1632	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ARZXY2_1633	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ARZXY2_1640	COG4804	nuclease activity
ARZXY2_1647	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ARZXY2_165	COG0800	Aldolase
ARZXY2_1650	COG2135	peptidase activity
ARZXY2_1655	COG0587	DNA-directed DNA polymerase activity
ARZXY2_1656	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ARZXY2_1659	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ARZXY2_1660	COG0339	signal peptide processing
ARZXY2_1664	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ARZXY2_1665	COG0217	transcriptional regulatory protein
ARZXY2_1666	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ARZXY2_1667	COG0632	four-way junction helicase activity
ARZXY2_1668	COG2255	four-way junction helicase activity
ARZXY2_1670	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ARZXY2_1671	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ARZXY2_1672	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ARZXY2_1674	COG1196	nuclear chromosome segregation
ARZXY2_1676	COG0124	histidyl-tRNA synthetase
ARZXY2_1678	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ARZXY2_1682	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ARZXY2_1685	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ARZXY2_1688	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ARZXY2_1688	COG0710	3-dehydroquinate dehydratase activity
ARZXY2_1689	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ARZXY2_1690	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ARZXY2_1691	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ARZXY2_1693	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ARZXY2_1694	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ARZXY2_1696	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ARZXY2_1697	COG0540	Belongs to the ATCase OTCase family
ARZXY2_1698	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ARZXY2_1700	COG0505	Belongs to the CarA family
ARZXY2_1701	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ARZXY2_1702	COG0284	orotidine-5'-phosphate decarboxylase activity
ARZXY2_1704	COG0194	GDP metabolic process
ARZXY2_1705	COG1758	RNA polymerase activity
ARZXY2_1707	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ARZXY2_171	COG4221	oxidoreductase activity
ARZXY2_1710	COG0438	transferase activity, transferring glycosyl groups
ARZXY2_1712	COG0656	L-ascorbic acid biosynthetic process
ARZXY2_1713	COG2390	Transcriptional regulator
ARZXY2_1714	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ARZXY2_1715	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ARZXY2_1716	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ARZXY2_1717	COG0495	leucyl-tRNA aminoacylation
ARZXY2_1718	COG1307	EDD domain protein, DegV family
ARZXY2_172	COG0477	Major facilitator Superfamily
ARZXY2_1722	COG0268	Binds directly to 16S ribosomal RNA
ARZXY2_1724	COG0481	GTPase activity
ARZXY2_1728	COG1420	regulation of RNA biosynthetic process
ARZXY2_1729	COG0484	heat shock protein binding
ARZXY2_1734	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ARZXY2_1736	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ARZXY2_1737	COG1316	TRANSCRIPTIONal
ARZXY2_1738	COG3590	peptidase
ARZXY2_1739	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ARZXY2_1740	COG1381	Involved in DNA repair and RecF pathway recombination
ARZXY2_1741	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ARZXY2_1742	COG2267	carboxylic ester hydrolase activity
ARZXY2_1745	COG0167	dihydroorotate dehydrogenase activity
ARZXY2_1749	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ARZXY2_175	COG1105	Belongs to the carbohydrate kinase PfkB family
ARZXY2_1750	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ARZXY2_1752	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ARZXY2_1754	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ARZXY2_1755	COG0723	plastoquinol--plastocyanin reductase activity
ARZXY2_1756	COG2010	Cytochrome c
ARZXY2_1757	COG1845	cytochrome c oxidase, subunit III
ARZXY2_1758	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ARZXY2_176	COG3958	Transketolase
ARZXY2_177	COG3959	Transketolase, thiamine diphosphate binding domain
ARZXY2_1770	COG1126	abc transporter atp-binding protein
ARZXY2_1772	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ARZXY2_1780	COG0667	Aldo Keto reductase
ARZXY2_1782	COG3424	synthase
ARZXY2_1783	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ARZXY2_1786	COG0242	peptide deformylase activity
ARZXY2_1787	COG4946	Tricorn protease homolog
ARZXY2_1787	COG1506	peptidase
ARZXY2_1787	COG0823	Involved in the tonB-independent uptake of proteins
ARZXY2_1788	COG2226	methyltransferase
ARZXY2_1792	COG1216	Glycosyl transferase, family 2
ARZXY2_1793	COG1574	metal-dependent hydrolase with the TIM-barrel fold
ARZXY2_1794	COG4581	dead DEAH box helicase
ARZXY2_1795	COG0805	protein transport
ARZXY2_1796	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ARZXY2_1800	COG0545	Peptidyl-prolyl cis-trans isomerase
ARZXY2_1801	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
ARZXY2_1802	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
ARZXY2_1803	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
ARZXY2_1805	COG4122	O-methyltransferase activity
ARZXY2_1806	COG1222	aaa ATPase
ARZXY2_1809	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ARZXY2_1811	COG0215	cysteine-tRNA ligase activity
ARZXY2_1812	COG1968	undecaprenyl-diphosphatase activity
ARZXY2_1813	COG0656	L-ascorbic acid biosynthetic process
ARZXY2_1814	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ARZXY2_1815	COG1088	dTDP-glucose 4,6-dehydratase activity
ARZXY2_1829	COG0673	inositol 2-dehydrogenase activity
ARZXY2_1830	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ARZXY2_1838	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_1839	COG0183	Belongs to the thiolase family
ARZXY2_1841	COG1960	acyl-CoA dehydrogenase activity
ARZXY2_1842	COG0297	glycogen (starch) synthase activity
ARZXY2_1843	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ARZXY2_1845	COG1305	Transglutaminase-like
ARZXY2_1850	COG0254	rRNA binding
ARZXY2_1853	COG1119	ATPase activity
ARZXY2_1854	COG3830	Belongs to the UPF0237 family
ARZXY2_1854	COG0560	Phosphoserine phosphatase
ARZXY2_1856	COG1129	ABC transporter
ARZXY2_1857	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_1858	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_1863	COG0488	(ABC) transporter
ARZXY2_1865	COG1268	BioY protein
ARZXY2_1866	COG1122	ATPase activity
ARZXY2_1869	COG0318	PFAM AMP-dependent synthetase and ligase
ARZXY2_1871	COG2151	metal-sulfur cluster biosynthetic enzyme
ARZXY2_1872	COG0396	ATPase activity
ARZXY2_1877	COG1131	(ABC) transporter
ARZXY2_1879	COG1612	heme a metabolic process
ARZXY2_188	COG3177	Filamentation induced by cAMP protein fic
ARZXY2_1880	COG0109	protoheme IX farnesyltransferase activity
ARZXY2_1882	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ARZXY2_1883	COG0166	Belongs to the GPI family
ARZXY2_1886	COG0363	glucosamine-6-phosphate deaminase activity
ARZXY2_1887	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ARZXY2_1888	COG0149	triose-phosphate isomerase activity
ARZXY2_1889	COG0126	phosphoglycerate kinase activity
ARZXY2_1890	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ARZXY2_1892	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ARZXY2_1893	COG1481	regulation of sporulation
ARZXY2_1895	COG1660	Displays ATPase and GTPase activities
ARZXY2_1896	COG0322	excinuclease ABC activity
ARZXY2_1898	COG0546	phosphoglycolate phosphatase activity
ARZXY2_1902	COG4106	trans-aconitate 2-methyltransferase activity
ARZXY2_1904	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ARZXY2_1908	COG0861	Integral membrane protein TerC family
ARZXY2_1909	COG0556	nucleotide-excision repair
ARZXY2_191	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ARZXY2_1910	COG0237	dephospho-CoA kinase activity
ARZXY2_1910	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ARZXY2_1911	COG1739	Uncharacterized protein family UPF0029
ARZXY2_1912	COG0539	negative regulation of cytoplasmic translation
ARZXY2_1914	COG4552	Acetyltransferase involved in intracellular survival and related
ARZXY2_1916	COG2050	protein possibly involved in aromatic compounds catabolism
ARZXY2_1923	COG3483	tryptophan 2,3-dioxygenase activity
ARZXY2_1926	COG2971	BadF BadG BcrA BcrD
ARZXY2_1930	COG0009	L-threonylcarbamoyladenylate synthase
ARZXY2_1938	COG1643	Atp-dependent helicase
ARZXY2_1939	COG1064	alcohol dehydrogenase
ARZXY2_1942	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ARZXY2_1947	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ARZXY2_1951	COG3285	dna ligase
ARZXY2_1951	COG1793	dna ligase
ARZXY2_1952	COG0028	Belongs to the TPP enzyme family
ARZXY2_1955	COG1802	Transcriptional regulator
ARZXY2_1958	COG3971	2-oxopent-4-enoate hydratase activity
ARZXY2_1965	COG2814	Major facilitator Superfamily
ARZXY2_1970	COG0179	Fumarylacetoacetate (FAA) hydrolase
ARZXY2_1971	COG0251	oxidation-reduction process
ARZXY2_1975	COG0572	uridine kinase
ARZXY2_198	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ARZXY2_1985	COG2197	response regulator
ARZXY2_1986	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
ARZXY2_1987	COG1846	Transcriptional regulator
ARZXY2_199	COG2807	transmembrane transport
ARZXY2_1994	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_1999	COG1012	belongs to the aldehyde dehydrogenase family
ARZXY2_200	COG0477	Major facilitator Superfamily
ARZXY2_2000	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ARZXY2_2000	COG3608	succinylglutamate desuccinylase aspartoacylase
ARZXY2_2002	COG2080	2 iron, 2 sulfur cluster binding
ARZXY2_2004	COG2175	clavaminate synthase activity
ARZXY2_2005	COG0477	Major facilitator Superfamily
ARZXY2_2010	COG3842	ATPase activity
ARZXY2_2012	COG1228	amidohydrolase
ARZXY2_2013	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ARZXY2_2014	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ARZXY2_2020	COG1172	Belongs to the binding-protein-dependent transport system permease family
ARZXY2_2021	COG1129	ABC transporter
ARZXY2_2023	COG0673	inositol 2-dehydrogenase activity
ARZXY2_2025	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ARZXY2_2026	COG0129	dihydroxy-acid dehydratase activity
ARZXY2_2027	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_2029	COG0673	inositol 2-dehydrogenase activity
ARZXY2_203	COG2813	Specifically methylates the guanine in position
ARZXY2_2030	COG1012	belongs to the aldehyde dehydrogenase family
ARZXY2_2031	COG3962	Belongs to the TPP enzyme family
ARZXY2_2035	COG0179	Fumarylacetoacetate (FAA) hydrolase
ARZXY2_2036	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ARZXY2_2042	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
ARZXY2_2043	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ARZXY2_2047	COG0857	belongs to the CobB CobQ family
ARZXY2_2047	COG0280	phosphate acetyltransferase
ARZXY2_2057	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ARZXY2_2062	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ARZXY2_2063	COG0508	dehydrogenase complex catalyzes the overall conversion of
ARZXY2_2064	COG0022	dehydrogenase e1 component
ARZXY2_2064	COG0508	dehydrogenase complex catalyzes the overall conversion of
ARZXY2_2065	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ARZXY2_2066	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ARZXY2_2067	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ARZXY2_2068	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ARZXY2_2076	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ARZXY2_2080	COG1937	Protein conserved in bacteria
ARZXY2_2083	COG0574	Belongs to the PEP-utilizing enzyme family
ARZXY2_2083	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ARZXY2_2087	COG1131	(ABC) transporter
ARZXY2_2090	COG0726	polysaccharide deacetylase
ARZXY2_2093	COG1131	(ABC) transporter
ARZXY2_2099	COG0861	Integral membrane protein TerC family
ARZXY2_210	COG2076	Multidrug Resistance protein
ARZXY2_2101	COG1349	DNA-binding transcription factor activity
ARZXY2_2102	COG0673	inositol 2-dehydrogenase activity
ARZXY2_2104	COG3684	Belongs to the aldolase LacD family
ARZXY2_2106	COG1175	transmembrane transport
ARZXY2_211	COG2076	Multidrug Resistance protein
ARZXY2_2111	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ARZXY2_2113	COG2132	Multicopper oxidase
ARZXY2_2116	COG2217	Heavy metal translocating P-type atpase
ARZXY2_2124	COG3415	Transposase
ARZXY2_2124	COG2801	Transposase and inactivated derivatives
ARZXY2_213	COG0135	phosphoribosylanthranilate isomerase activity
ARZXY2_2133	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ARZXY2_2134	COG1349	DNA-binding transcription factor activity
ARZXY2_2140	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_2147	COG0070	glutamate synthase
ARZXY2_2147	COG0069	glutamate synthase activity
ARZXY2_2147	COG0067	glutamate synthase
ARZXY2_2148	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ARZXY2_2149	COG0159	tryptophan synthase activity
ARZXY2_215	COG3304	Inner membrane component domain
ARZXY2_2150	COG0133	tryptophan synthase activity
ARZXY2_2151	COG0134	indole-3-glycerol-phosphate synthase activity
ARZXY2_2155	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ARZXY2_2157	COG0107	imidazoleglycerol-phosphate synthase activity
ARZXY2_2158	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ARZXY2_2159	COG0140	phosphoribosyl-ATP diphosphatase activity
ARZXY2_2160	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ARZXY2_2161	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ARZXY2_2162	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ARZXY2_2162	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ARZXY2_2166	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ARZXY2_2168	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ARZXY2_2169	COG0242	peptide deformylase activity
ARZXY2_2181	COG0531	amino acid
ARZXY2_2183	COG3135	benzoate transporter
ARZXY2_2187	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ARZXY2_219	COG3585	molybdate ion transport
ARZXY2_2190	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ARZXY2_2195	COG0183	Belongs to the thiolase family
ARZXY2_2196	COG1024	Enoyl-CoA hydratase
ARZXY2_2196	COG1250	3-hydroxyacyl-CoA dehydrogenase
ARZXY2_2197	COG0667	Aldo Keto reductase
ARZXY2_22	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ARZXY2_2201	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ARZXY2_2202	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ARZXY2_2203	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ARZXY2_2204	COG0531	amino acid
ARZXY2_2205	COG0569	domain protein
ARZXY2_2210	COG0756	dUTP diphosphatase activity
ARZXY2_2214	COG1435	thymidine kinase activity
ARZXY2_2217	COG1042	CoA-binding domain protein
ARZXY2_2217	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ARZXY2_2217	COG0045	succinate-CoA ligase (ADP-forming) activity
ARZXY2_2218	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ARZXY2_2222	COG4988	ABC transporter
ARZXY2_2223	COG1294	oxidase, subunit
ARZXY2_2224	COG1271	oxidase subunit
ARZXY2_2229	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ARZXY2_2234	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ARZXY2_2235	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ARZXY2_2236	COG0508	dehydrogenase complex catalyzes the overall conversion of
ARZXY2_2238	COG1764	response to oxidative stress
ARZXY2_2239	COG1090	epimerase
ARZXY2_224	COG0542	response to heat
ARZXY2_2240	COG0793	Belongs to the peptidase S41A family
ARZXY2_2240	COG4946	Tricorn protease homolog
ARZXY2_2242	COG0321	lipoyl(octanoyl) transferase activity
ARZXY2_2243	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ARZXY2_2250	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ARZXY2_2252	COG0174	glutamine synthetase
ARZXY2_2253	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ARZXY2_2257	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ARZXY2_2259	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ARZXY2_2262	COG0587	DNA-directed DNA polymerase activity
ARZXY2_2264	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ARZXY2_2267	COG1799	cell septum assembly
ARZXY2_2268	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ARZXY2_2271	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ARZXY2_2273	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ARZXY2_2274	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ARZXY2_2276	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ARZXY2_2277	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ARZXY2_2279	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ARZXY2_2280	COG0768	penicillin binding
ARZXY2_2282	COG0275	rRNA processing
ARZXY2_2283	COG2001	Belongs to the MraZ family
ARZXY2_2288	COG0142	geranyltranstransferase activity
ARZXY2_2290	COG3942	CHAP domain
ARZXY2_2290	COG1388	LysM domain
ARZXY2_2291	COG0515	serine threonine protein kinase
ARZXY2_2291	COG2815	serine threonine protein kinase
ARZXY2_2292	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ARZXY2_2297	COG1940	carbohydrate kinase activity
ARZXY2_2299	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ARZXY2_2305	COG1716	ATPase activity
ARZXY2_2307	COG0509	glycine decarboxylation via glycine cleavage system
ARZXY2_2308	COG3415	Transposase
ARZXY2_2308	COG2801	Transposase and inactivated derivatives
ARZXY2_2309	COG2814	Major facilitator Superfamily
ARZXY2_231	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ARZXY2_2312	COG1160	GTP binding
ARZXY2_2314	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ARZXY2_2317	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ARZXY2_2318	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ARZXY2_2320	COG1301	dicarboxylic acid transport
ARZXY2_2321	COG3290	protein histidine kinase activity
ARZXY2_2324	COG2079	MmgE PrpD family protein
ARZXY2_2325	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ARZXY2_2331	COG0504	CTP synthase activity
ARZXY2_2332	COG0497	DNA recombination
ARZXY2_2333	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ARZXY2_2336	COG0647	UMP catabolic process
ARZXY2_2343	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ARZXY2_2345	COG2094	Belongs to the DNA glycosylase MPG family
ARZXY2_2348	COG0165	Argininosuccinate lyase
ARZXY2_2349	COG0137	argininosuccinate synthase activity
ARZXY2_2350	COG1438	arginine binding
ARZXY2_2351	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ARZXY2_2352	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ARZXY2_2353	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ARZXY2_2354	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ARZXY2_2355	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ARZXY2_2358	COG0072	phenylalanine-tRNA ligase activity
ARZXY2_2358	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ARZXY2_2359	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ARZXY2_236	COG0671	phosphoesterase, PA-phosphatase related
ARZXY2_2362	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
ARZXY2_2364	COG2816	NAD+ diphosphatase activity
ARZXY2_2365	COG2814	Major facilitator Superfamily
ARZXY2_2366	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ARZXY2_2367	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ARZXY2_2368	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ARZXY2_2369	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ARZXY2_237	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ARZXY2_2373	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ARZXY2_2375	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ARZXY2_2376	COG0131	Imidazoleglycerol-phosphate dehydratase
ARZXY2_2377	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ARZXY2_2378	COG1388	LysM domain
ARZXY2_2379	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ARZXY2_2381	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ARZXY2_2382	COG2813	Specifically methylates the guanine in position
ARZXY2_2383	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ARZXY2_2384	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ARZXY2_2385	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ARZXY2_2386	COG2137	regulation of response to DNA damage stimulus
ARZXY2_2387	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ARZXY2_2390	COG1396	sequence-specific DNA binding
ARZXY2_2391	COG1546	Belongs to the CinA family
ARZXY2_2391	COG1058	Belongs to the CinA family
ARZXY2_2393	COG1674	ftsk spoiiie
ARZXY2_2394	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ARZXY2_2395	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ARZXY2_2399	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ARZXY2_24	COG1937	Protein conserved in bacteria
ARZXY2_240	COG3415	Transposase
ARZXY2_240	COG2801	Transposase and inactivated derivatives
ARZXY2_2401	COG0521	Mo-molybdopterin cofactor biosynthetic process
ARZXY2_2405	COG2205	protein histidine kinase activity
ARZXY2_2406	COG0745	RESPONSE REGULATOR receiver
ARZXY2_2410	COG0612	Peptidase, M16
ARZXY2_2411	COG1185	polyribonucleotide nucleotidyltransferase activity
ARZXY2_2412	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ARZXY2_2416	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ARZXY2_2418	COG0590	tRNA wobble adenosine to inosine editing
ARZXY2_2419	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ARZXY2_2421	COG0481	GTPase activity
ARZXY2_2421	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ARZXY2_2424	COG0779	Required for maturation of 30S ribosomal subunits
ARZXY2_2428	COG0442	prolyl-tRNA aminoacylation
ARZXY2_2429	COG1131	(ABC) transporter
ARZXY2_2433	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ARZXY2_2435	COG0750	zinc metalloprotease
ARZXY2_2436	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ARZXY2_2439	COG1653	transport
ARZXY2_244	COG1366	Belongs to the anti-sigma-factor antagonist family
ARZXY2_2440	COG1175	transmembrane transport
ARZXY2_2442	COG0673	inositol 2-dehydrogenase activity
ARZXY2_2450	COG1960	acyl-CoA dehydrogenase activity
ARZXY2_2452	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ARZXY2_2454	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ARZXY2_2455	COG0508	dehydrogenase complex catalyzes the overall conversion of
ARZXY2_2456	COG0022	dehydrogenase e1 component
ARZXY2_2458	COG1522	sequence-specific DNA binding
ARZXY2_246	COG0745	RESPONSE REGULATOR receiver
ARZXY2_2460	COG1796	DNA polymerase
ARZXY2_2460	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ARZXY2_2461	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ARZXY2_2463	COG3275	phosphorelay sensor kinase activity
ARZXY2_2466	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ARZXY2_2469	COG0575	Belongs to the CDS family
ARZXY2_2470	COG0233	cytoplasmic translational termination
ARZXY2_2471	COG0528	UMP kinase activity
ARZXY2_2472	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ARZXY2_2473	COG0052	Belongs to the universal ribosomal protein uS2 family
ARZXY2_2476	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
ARZXY2_249	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ARZXY2_250	COG1929	Belongs to the glycerate kinase type-1 family
ARZXY2_251	COG3960	tartronate-semialdehyde synthase activity
ARZXY2_252	COG2084	Dehydrogenase
ARZXY2_253	COG3622	Belongs to the hyi family
ARZXY2_2543	COG0297	glycogen (starch) synthase activity
ARZXY2_2549	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ARZXY2_2550	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ARZXY2_2554	COG0358	DNA primase activity
ARZXY2_2559	COG0423	glycine-tRNA ligase activity
ARZXY2_256	COG1609	Transcriptional regulator
ARZXY2_2565	COG2801	Transposase and inactivated derivatives
ARZXY2_2565	COG3415	Transposase
ARZXY2_2567	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ARZXY2_2568	COG2873	o-acetylhomoserine
ARZXY2_2574	COG1940	carbohydrate kinase activity
ARZXY2_2575	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ARZXY2_2576	COG1228	amidohydrolase
ARZXY2_2578	COG0156	8-amino-7-oxononanoate synthase activity
ARZXY2_2579	COG1063	alcohol dehydrogenase
ARZXY2_258	COG1653	transport
ARZXY2_2581	COG0673	inositol 2-dehydrogenase activity
ARZXY2_2586	COG0395	ABC-type sugar transport system, permease component
ARZXY2_2587	COG4209	transmembrane transport
ARZXY2_2588	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ARZXY2_2589	COG0154	amidase activity
ARZXY2_2590	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ARZXY2_2591	COG2851	Citrate transporter
ARZXY2_2593	COG4565	transcriptional regulatory protein
ARZXY2_2594	COG0251	oxidation-reduction process
ARZXY2_2598	COG0483	inositol monophosphate 1-phosphatase activity
ARZXY2_2599	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ARZXY2_2601	COG1674	ftsk spoiiie
ARZXY2_261	COG0673	inositol 2-dehydrogenase activity
ARZXY2_2611	COG0714	Associated with various cellular activities
ARZXY2_2618	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ARZXY2_2624	COG1309	transcriptional regulator
ARZXY2_2625	COG2409	Drug exporters of the RND superfamily
ARZXY2_2626	COG0424	maF-like protein
ARZXY2_2627	COG4770	biotin carboxylase activity
ARZXY2_2628	COG0477	Major facilitator Superfamily
ARZXY2_2629	COG2223	nitrite transmembrane transporter activity
ARZXY2_2630	COG2223	nitrite transmembrane transporter activity
ARZXY2_2631	COG0243	molybdopterin cofactor binding
ARZXY2_2637	COG1621	beta-fructofuranosidase activity
ARZXY2_2638	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ARZXY2_2640	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ARZXY2_2644	COG0659	secondary active sulfate transmembrane transporter activity
ARZXY2_2645	COG2824	Alkylphosphonate utilization operon protein PhnA
ARZXY2_2646	COG2814	Major facilitator Superfamily
ARZXY2_2649	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_2657	COG0446	pyridine nucleotide-disulphide oxidoreductase
ARZXY2_2658	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ARZXY2_266	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ARZXY2_2661	COG0297	glycogen (starch) synthase activity
ARZXY2_2665	COG1988	membrane-bound metal-dependent
ARZXY2_2667	COG0702	epimerase
ARZXY2_267	COG1454	alcohol dehydrogenase
ARZXY2_2670	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ARZXY2_2671	COG0822	iron-sulfur transferase activity
ARZXY2_2677	COG0193	aminoacyl-tRNA hydrolase activity
ARZXY2_2678	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ARZXY2_2679	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ARZXY2_2680	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ARZXY2_2684	COG0488	(ABC) transporter
ARZXY2_2685	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ARZXY2_2686	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ARZXY2_2687	COG3583	domain protein
ARZXY2_2688	COG0084	hydrolase, TatD family'
ARZXY2_2689	COG0714	Associated with various cellular activities
ARZXY2_2701	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ARZXY2_2711	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ARZXY2_2713	COG1482	cell wall glycoprotein biosynthetic process
ARZXY2_2715	COG1494	fructose-1,6-bisphosphatase
ARZXY2_2717	COG0288	reversible hydration of carbon dioxide
ARZXY2_2718	COG0114	fumarate hydratase activity
ARZXY2_2722	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ARZXY2_2723	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ARZXY2_2725	COG1331	Highly conserved protein containing a thioredoxin domain
ARZXY2_2728	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ARZXY2_2729	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ARZXY2_2731	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ARZXY2_2733	COG2017	converts alpha-aldose to the beta-anomer
ARZXY2_2735	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ARZXY2_2736	COG0183	Belongs to the thiolase family
ARZXY2_2738	COG0559	Belongs to the binding-protein-dependent transport system permease family
ARZXY2_2746	COG1252	NADH dehydrogenase
ARZXY2_2751	COG0148	phosphopyruvate hydratase activity
ARZXY2_2753	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ARZXY2_2754	COG0586	Pfam SNARE associated Golgi protein
ARZXY2_2763	COG2130	NADP-dependent
ARZXY2_2764	COG1764	response to oxidative stress
ARZXY2_2765	COG1846	Transcriptional regulator
ARZXY2_2766	COG1473	amidohydrolase
ARZXY2_2766	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ARZXY2_2769	COG2009	succinate dehydrogenase
ARZXY2_277	COG0405	Gamma-glutamyltransferase
ARZXY2_2772	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ARZXY2_2779	COG0180	Tryptophanyl-tRNA synthetase
ARZXY2_2784	COG1131	(ABC) transporter
ARZXY2_2785	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ARZXY2_2786	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ARZXY2_2791	COG0531	amino acid
ARZXY2_2792	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ARZXY2_2795	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ARZXY2_2797	COG1129	ABC transporter
ARZXY2_2798	COG4214	carbohydrate transport
ARZXY2_2799	COG4213	ABC transporter substrate-binding protein
ARZXY2_28	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ARZXY2_2800	COG1136	(ABC) transporter
ARZXY2_2800	COG0577	efflux transmembrane transporter activity
ARZXY2_2801	COG0577	efflux transmembrane transporter activity
ARZXY2_2801	COG1136	(ABC) transporter
ARZXY2_2803	COG0673	inositol 2-dehydrogenase activity
ARZXY2_2806	COG2838	Isocitrate dehydrogenase
ARZXY2_2808	COG0138	bifunctional purine biosynthesis protein purh
ARZXY2_2810	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ARZXY2_2811	COG2271	Major facilitator Superfamily
ARZXY2_2817	COG0484	heat shock protein binding
ARZXY2_2818	COG0071	Belongs to the small heat shock protein (HSP20) family
ARZXY2_2819	COG0789	Transcriptional regulator
ARZXY2_2823	COG3415	Transposase
ARZXY2_2823	COG2801	Transposase and inactivated derivatives
ARZXY2_2826	COG1278	Cold shock
ARZXY2_2827	COG4942	peptidase
ARZXY2_2832	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_2848	COG0861	Integral membrane protein TerC family
ARZXY2_2855	COG3973	AAA domain
ARZXY2_2858	COG0477	Major facilitator Superfamily
ARZXY2_2861	COG1609	Transcriptional regulator
ARZXY2_2870	COG0402	S-adenosylhomocysteine deaminase activity
ARZXY2_2872	COG1653	transport
ARZXY2_2873	COG0395	ABC-type sugar transport system, permease component
ARZXY2_2874	COG0395	ABC-type sugar transport system, permease component
ARZXY2_2875	COG4209	transmembrane transport
ARZXY2_2877	COG0640	Transcriptional regulator
ARZXY2_2879	COG1254	Belongs to the acylphosphatase family
ARZXY2_2881	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ARZXY2_2884	COG3835	regulator
ARZXY2_2886	COG0511	ligase activity, forming carbon-carbon bonds
ARZXY2_2887	COG0439	Biotin carboxylase
ARZXY2_2888	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ARZXY2_2889	COG1984	allophanate hydrolase subunit 2
ARZXY2_2896	COG0149	triose-phosphate isomerase activity
ARZXY2_2898	COG2271	Major facilitator Superfamily
ARZXY2_2900	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_2901	COG1250	3-hydroxyacyl-CoA dehydrogenase
ARZXY2_2902	COG0698	ribose 5-phosphate isomerase
ARZXY2_2903	COG2376	Dihydroxyacetone kinase
ARZXY2_2906	COG1902	pentaerythritol trinitrate reductase activity
ARZXY2_2907	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ARZXY2_2911	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ARZXY2_2915	COG1396	sequence-specific DNA binding
ARZXY2_2918	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ARZXY2_2919	COG1024	Enoyl-CoA hydratase
ARZXY2_292	COG2267	carboxylic ester hydrolase activity
ARZXY2_2921	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_2922	COG1012	belongs to the aldehyde dehydrogenase family
ARZXY2_2925	COG2205	protein histidine kinase activity
ARZXY2_2928	COG1401	restriction endodeoxyribonuclease activity
ARZXY2_2930	COG3142	Participates in the control of copper homeostasis
ARZXY2_2936	COG0028	Belongs to the TPP enzyme family
ARZXY2_2938	COG1396	sequence-specific DNA binding
ARZXY2_2949	COG0673	inositol 2-dehydrogenase activity
ARZXY2_2951	COG1172	Belongs to the binding-protein-dependent transport system permease family
ARZXY2_2954	COG3718	enzyme involved in inositol metabolism
ARZXY2_2955	COG1082	Xylose isomerase domain protein TIM barrel
ARZXY2_2956	COG0673	inositol 2-dehydrogenase activity
ARZXY2_2959	COG3962	Belongs to the TPP enzyme family
ARZXY2_296	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ARZXY2_2961	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ARZXY2_2962	COG1942	4-Oxalocrotonate Tautomerase
ARZXY2_2964	COG0045	succinate-CoA ligase (ADP-forming) activity
ARZXY2_2968	COG0483	inositol monophosphate 1-phosphatase activity
ARZXY2_297	COG3311	Transcriptional regulator
ARZXY2_2975	COG1132	(ABC) transporter
ARZXY2_2976	COG0488	(ABC) transporter
ARZXY2_2979	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ARZXY2_2980	COG0765	amino acid transport
ARZXY2_2981	COG1126	abc transporter atp-binding protein
ARZXY2_2985	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ARZXY2_2987	COG0746	molybdenum cofactor guanylyltransferase activity
ARZXY2_2990	COG3103	Sh3 type 3 domain protein
ARZXY2_2990	COG1388	LysM domain
ARZXY2_2990	COG0791	NLP P60 protein
ARZXY2_2991	COG0739	heme binding
ARZXY2_2995	COG1278	Cold shock
ARZXY2_30	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ARZXY2_3000	COG2132	Multicopper oxidase
ARZXY2_3005	COG0745	RESPONSE REGULATOR receiver
ARZXY2_3006	COG2205	protein histidine kinase activity
ARZXY2_3009	COG0459	protein refolding
ARZXY2_301	COG0300	oxidoreductase activity
ARZXY2_3014	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ARZXY2_3021	COG0577	efflux transmembrane transporter activity
ARZXY2_3021	COG1136	(ABC) transporter
ARZXY2_3024	COG1864	DNA RNA non-specific endonuclease
ARZXY2_3024	COG3591	Belongs to the peptidase S1B family
ARZXY2_3027	COG0509	glycine decarboxylation via glycine cleavage system
ARZXY2_3028	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ARZXY2_3029	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ARZXY2_3029	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ARZXY2_303	COG3401	FG-GAP repeat protein
ARZXY2_3031	COG0477	Major facilitator Superfamily
ARZXY2_3034	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ARZXY2_3036	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ARZXY2_3037	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ARZXY2_3039	COG1987	bacterial-type flagellum assembly
ARZXY2_3040	COG1338	Plays a role in the flagellum-specific transport system
ARZXY2_3044	COG1360	Flagellar Motor Protein
ARZXY2_3045	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ARZXY2_3048	COG3550	peptidyl-serine autophosphorylation
ARZXY2_305	COG0563	adenylate kinase activity
ARZXY2_3052	COG0791	NLP P60 protein
ARZXY2_3054	COG1157	protein secretion by the type III secretion system
ARZXY2_3056	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ARZXY2_3057	COG1766	The M ring may be actively involved in energy transduction
ARZXY2_3058	COG1677	Flagellar hook-basal body complex protein FliE
ARZXY2_3060	COG1815	bacterial-type flagellum-dependent cell motility
ARZXY2_3062	COG1473	amidohydrolase
ARZXY2_3066	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ARZXY2_3068	COG1256	bacterial-type flagellum assembly
ARZXY2_3068	COG4786	Flagellar basal body rod
ARZXY2_3070	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
ARZXY2_3073	COG1609	Transcriptional regulator
ARZXY2_3075	COG0492	ferredoxin-NADP+ reductase activity
ARZXY2_3077	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ARZXY2_3078	COG2957	Belongs to the agmatine deiminase family
ARZXY2_3083	COG0579	oxidoreductase
ARZXY2_309	COG0659	secondary active sulfate transmembrane transporter activity
ARZXY2_3091	COG1252	NADH dehydrogenase
ARZXY2_3093	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ARZXY2_3096	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_3097	COG0475	glutathione-regulated potassium exporter activity
ARZXY2_3104	COG3842	ATPase activity
ARZXY2_3110	COG0277	FAD linked oxidase domain protein
ARZXY2_3118	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ARZXY2_3120	COG0366	Alpha amylase catalytic
ARZXY2_3128	COG0215	cysteine-tRNA ligase activity
ARZXY2_3130	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ARZXY2_3131	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ARZXY2_3135	COG5002	protein histidine kinase activity
ARZXY2_3137	COG0588	phosphoglycerate mutase activity
ARZXY2_3142	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ARZXY2_3143	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ARZXY2_315	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ARZXY2_3155	COG0656	L-ascorbic acid biosynthetic process
ARZXY2_3159	COG1966	Carbon starvation protein
ARZXY2_316	COG4585	Histidine kinase
ARZXY2_3161	COG0604	alcohol dehydrogenase
ARZXY2_3161	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_3161	COG3321	synthase
ARZXY2_3164	COG1113	amino acid transport
ARZXY2_3166	COG1505	serine-type exopeptidase activity
ARZXY2_3169	COG0514	ATP-dependent DNA helicase (RecQ)
ARZXY2_317	COG2318	DinB family
ARZXY2_3170	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ARZXY2_3173	COG1017	nitric oxide dioxygenase activity
ARZXY2_3173	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ARZXY2_3174	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
ARZXY2_3180	COG0747	negative chemotaxis
ARZXY2_3181	COG0601	transmembrane transport
ARZXY2_3182	COG0444	Belongs to the ABC transporter superfamily
ARZXY2_3183	COG4608	Belongs to the ABC transporter superfamily
ARZXY2_3184	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ARZXY2_3185	COG1940	carbohydrate kinase activity
ARZXY2_3186	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
ARZXY2_3188	COG1129	ABC transporter
ARZXY2_3189	COG1511	domain protein
ARZXY2_3190	COG1309	transcriptional regulator
ARZXY2_3192	COG0697	spore germination
ARZXY2_3193	COG0583	DNA-binding transcription factor activity
ARZXY2_3194	COG2062	phosphohistidine phosphatase, SixA
ARZXY2_320	COG3257	ureidoglycine aminohydrolase activity
ARZXY2_3200	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ARZXY2_3202	COG0438	transferase activity, transferring glycosyl groups
ARZXY2_3217	COG1201	RNA secondary structure unwinding
ARZXY2_3218	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ARZXY2_3219	COG2364	Membrane
ARZXY2_3220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ARZXY2_3223	COG0564	pseudouridine synthase activity
ARZXY2_3225	COG0586	Pfam SNARE associated Golgi protein
ARZXY2_3227	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ARZXY2_3230	COG1215	transferase activity, transferring glycosyl groups
ARZXY2_3232	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ARZXY2_3237	COG1960	acyl-CoA dehydrogenase activity
ARZXY2_324	COG1414	Transcriptional regulator
ARZXY2_3242	COG3842	ATPase activity
ARZXY2_3245	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ARZXY2_3246	COG1574	metal-dependent hydrolase with the TIM-barrel fold
ARZXY2_3247	COG1012	belongs to the aldehyde dehydrogenase family
ARZXY2_3248	COG0028	Belongs to the TPP enzyme family
ARZXY2_3249	COG0477	Major facilitator Superfamily
ARZXY2_325	COG2233	PERMEase
ARZXY2_3250	COG2508	Transcriptional regulator
ARZXY2_3251	COG0477	Major facilitator Superfamily
ARZXY2_3253	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ARZXY2_3257	COG0343	queuine tRNA-ribosyltransferase activity
ARZXY2_3259	COG1309	transcriptional regulator
ARZXY2_3260	COG1090	epimerase
ARZXY2_3263	COG0477	Major facilitator Superfamily
ARZXY2_3264	COG0745	RESPONSE REGULATOR receiver
ARZXY2_3265	COG0642	Histidine kinase
ARZXY2_3267	COG0351	phosphomethylpyrimidine kinase
ARZXY2_3269	COG1309	transcriptional regulator
ARZXY2_3270	COG1476	TRANSCRIPTIONal
ARZXY2_3277	COG0673	inositol 2-dehydrogenase activity
ARZXY2_3284	COG2855	membrane
ARZXY2_3287	COG4565	transcriptional regulatory protein
ARZXY2_3288	COG3290	protein histidine kinase activity
ARZXY2_3292	COG0589	response to stress
ARZXY2_3295	COG0438	transferase activity, transferring glycosyl groups
ARZXY2_3298	COG0395	ABC-type sugar transport system, permease component
ARZXY2_330	COG0590	tRNA wobble adenosine to inosine editing
ARZXY2_3302	COG1309	transcriptional regulator
ARZXY2_3308	COG0739	heme binding
ARZXY2_3308	COG0741	lytic transglycosylase activity
ARZXY2_3308	COG1196	nuclear chromosome segregation
ARZXY2_331	COG2252	PERMEase
ARZXY2_3310	COG1012	belongs to the aldehyde dehydrogenase family
ARZXY2_3313	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ARZXY2_3315	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ARZXY2_332	COG3608	succinylglutamate desuccinylase aspartoacylase
ARZXY2_332	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ARZXY2_3325	COG1846	Transcriptional regulator
ARZXY2_3331	COG1404	Belongs to the peptidase S8 family
ARZXY2_3333	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ARZXY2_3337	COG0047	phosphoribosylformylglycinamidine synthase activity
ARZXY2_3338	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ARZXY2_334	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ARZXY2_3341	COG3706	GGDEF domain
ARZXY2_3345	COG1175	transmembrane transport
ARZXY2_3347	COG2315	Protein conserved in bacteria
ARZXY2_3350	COG1832	CoA-binding protein
ARZXY2_3357	COG0395	ABC-type sugar transport system, permease component
ARZXY2_3358	COG1175	transmembrane transport
ARZXY2_3361	COG1621	beta-fructofuranosidase activity
ARZXY2_3364	COG0129	dihydroxy-acid dehydratase activity
ARZXY2_3366	COG2271	Major facilitator Superfamily
ARZXY2_337	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ARZXY2_3371	COG0477	Major facilitator Superfamily
ARZXY2_3372	COG1609	Transcriptional regulator
ARZXY2_3374	COG0765	amino acid transport
ARZXY2_3375	COG1126	abc transporter atp-binding protein
ARZXY2_3376	COG0673	inositol 2-dehydrogenase activity
ARZXY2_3377	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ARZXY2_338	COG1953	Uracil, thiamine, allantoin
ARZXY2_3383	COG2814	Major facilitator Superfamily
ARZXY2_3385	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ARZXY2_3390	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ARZXY2_3390	COG0357	Ribosomal RNA small subunit methyltransferase G
ARZXY2_3397	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ARZXY2_3399	COG4948	Mandelate Racemase Muconate Lactonizing
ARZXY2_34	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ARZXY2_340	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_3401	COG0246	Mannitol dehydrogenase
ARZXY2_3402	COG1904	glucuronate isomerase
ARZXY2_3403	COG1609	Transcriptional regulator
ARZXY2_3404	COG0673	inositol 2-dehydrogenase activity
ARZXY2_3407	COG0444	Belongs to the ABC transporter superfamily
ARZXY2_3409	COG0747	negative chemotaxis
ARZXY2_341	COG1301	dicarboxylic acid transport
ARZXY2_3412	COG1609	Transcriptional regulator
ARZXY2_3415	COG0789	Transcriptional regulator
ARZXY2_3418	COG3328	transposase activity
ARZXY2_342	COG1301	dicarboxylic acid transport
ARZXY2_3422	COG1960	acyl-CoA dehydrogenase activity
ARZXY2_3423	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ARZXY2_3430	COG1024	Enoyl-CoA hydratase
ARZXY2_3432	COG0415	Belongs to the DNA photolyase family
ARZXY2_3437	COG0583	DNA-binding transcription factor activity
ARZXY2_3439	COG1473	amidohydrolase
ARZXY2_3441	COG0174	glutamine synthetase
ARZXY2_3442	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ARZXY2_3447	COG0683	leucine binding
ARZXY2_345	COG0151	Belongs to the GarS family
ARZXY2_3452	COG1802	Transcriptional regulator
ARZXY2_3455	COG3404	Formiminotransferase-cyclodeaminase
ARZXY2_3456	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ARZXY2_3458	COG1063	alcohol dehydrogenase
ARZXY2_3459	COG0303	'Molybdopterin
ARZXY2_346	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ARZXY2_3460	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ARZXY2_3462	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ARZXY2_3467	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ARZXY2_3470	COG0666	response to abiotic stimulus
ARZXY2_3473	COG4585	Histidine kinase
ARZXY2_3474	COG2197	response regulator
ARZXY2_3478	COG1609	Transcriptional regulator
ARZXY2_3482	COG2182	Extracellular solute-binding protein
ARZXY2_3495	COG1285	pathogenesis
ARZXY2_3496	COG1175	transmembrane transport
ARZXY2_3497	COG0395	ABC-type sugar transport system, permease component
ARZXY2_3499	COG1802	Transcriptional regulator
ARZXY2_35	COG3387	PFAM Glycoside hydrolase 15-related
ARZXY2_350	COG1132	(ABC) transporter
ARZXY2_3507	COG1609	Transcriptional regulator
ARZXY2_351	COG1132	(ABC) transporter
ARZXY2_3510	COG3848	Pyruvate phosphate dikinase
ARZXY2_3510	COG0574	Belongs to the PEP-utilizing enzyme family
ARZXY2_3515	COG2252	PERMEase
ARZXY2_3516	COG0010	Belongs to the arginase family
ARZXY2_3518	COG2902	Dehydrogenase
ARZXY2_352	COG1408	metallophosphoesterase
ARZXY2_3523	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ARZXY2_3527	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_3539	COG2733	membrane
ARZXY2_354	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ARZXY2_3540	COG1984	allophanate hydrolase subunit 2
ARZXY2_3541	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ARZXY2_3546	COG2828	Protein conserved in bacteria
ARZXY2_3548	COG0673	inositol 2-dehydrogenase activity
ARZXY2_3550	COG0673	inositol 2-dehydrogenase activity
ARZXY2_3551	COG0673	inositol 2-dehydrogenase activity
ARZXY2_3553	COG0028	Belongs to the TPP enzyme family
ARZXY2_3554	COG0477	Major facilitator Superfamily
ARZXY2_3557	COG1309	transcriptional regulator
ARZXY2_3559	COG2301	Belongs to the HpcH HpaI aldolase family
ARZXY2_3560	COG4770	biotin carboxylase activity
ARZXY2_3562	COG0318	PFAM AMP-dependent synthetase and ligase
ARZXY2_3563	COG1309	transcriptional regulator
ARZXY2_3564	COG1902	pentaerythritol trinitrate reductase activity
ARZXY2_3565	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_3566	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ARZXY2_3568	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ARZXY2_3573	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ARZXY2_3577	COG0179	Fumarylacetoacetate (FAA) hydrolase
ARZXY2_3583	COG3971	2-oxopent-4-enoate hydratase activity
ARZXY2_3584	COG1414	Transcriptional regulator
ARZXY2_3586	COG3384	dioxygenase
ARZXY2_3587	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ARZXY2_3589	COG3842	ATPase activity
ARZXY2_359	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ARZXY2_3592	COG1846	Transcriptional regulator
ARZXY2_3593	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
ARZXY2_3594	COG0142	geranyltranstransferase activity
ARZXY2_3599	COG1846	Transcriptional regulator
ARZXY2_3604	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ARZXY2_3609	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ARZXY2_3614	COG1349	DNA-binding transcription factor activity
ARZXY2_3616	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ARZXY2_3616	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ARZXY2_3616	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ARZXY2_362	COG0395	ABC-type sugar transport system, permease component
ARZXY2_3627	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
ARZXY2_363	COG4209	transmembrane transport
ARZXY2_3631	COG2890	protein-(glutamine-N5) methyltransferase activity
ARZXY2_3632	COG0477	Major facilitator Superfamily
ARZXY2_3635	COG4948	Mandelate Racemase Muconate Lactonizing
ARZXY2_3638	COG1175	transmembrane transport
ARZXY2_3640	COG2186	Transcriptional regulator
ARZXY2_3641	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ARZXY2_3642	COG0697	spore germination
ARZXY2_3646	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_3649	COG3486	L-lysine 6-monooxygenase (NADPH) activity
ARZXY2_365	COG1609	Transcriptional regulator
ARZXY2_3660	COG2610	gluconate transmembrane transporter activity
ARZXY2_3661	COG2084	Dehydrogenase
ARZXY2_3664	COG2186	Transcriptional regulator
ARZXY2_3669	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ARZXY2_367	COG0577	efflux transmembrane transporter activity
ARZXY2_367	COG1136	(ABC) transporter
ARZXY2_3671	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
ARZXY2_3673	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_3674	COG3360	Dodecin
ARZXY2_3677	COG0667	Aldo Keto reductase
ARZXY2_3679	COG0656	L-ascorbic acid biosynthetic process
ARZXY2_368	COG1349	DNA-binding transcription factor activity
ARZXY2_3680	COG2706	6-phosphogluconolactonase activity
ARZXY2_3684	COG1595	DNA-templated transcription, initiation
ARZXY2_3685	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
ARZXY2_3686	COG0829	nickel cation binding
ARZXY2_3687	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ARZXY2_3688	COG0830	nickel cation binding
ARZXY2_3689	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
ARZXY2_369	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ARZXY2_3690	COG0804	urea catabolic process
ARZXY2_3691	COG0832	Belongs to the urease beta subunit family
ARZXY2_3692	COG0831	urea catabolic process
ARZXY2_37	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ARZXY2_3704	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ARZXY2_3710	COG0671	phosphoesterase, PA-phosphatase related
ARZXY2_3717	COG1247	-acetyltransferase
ARZXY2_3722	COG3559	Exporter of polyketide antibiotics
ARZXY2_3723	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ARZXY2_3724	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ARZXY2_3725	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ARZXY2_3726	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
ARZXY2_3734	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_3737	COG3237	CsbD-like
ARZXY2_3738	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
ARZXY2_3739	COG1461	Dihydroxyacetone kinase
ARZXY2_3740	COG2376	Dihydroxyacetone kinase
ARZXY2_3744	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ARZXY2_3745	COG1506	peptidase
ARZXY2_3745	COG0823	Involved in the tonB-independent uptake of proteins
ARZXY2_3751	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ARZXY2_3759	COG0477	Major facilitator Superfamily
ARZXY2_3764	COG3328	transposase activity
ARZXY2_3768	COG2814	Major facilitator Superfamily
ARZXY2_3769	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ARZXY2_3775	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ARZXY2_3777	COG0302	gtp cyclohydrolase
ARZXY2_3778	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ARZXY2_3781	COG0037	tRNA processing
ARZXY2_3794	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ARZXY2_3794	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ARZXY2_3797	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ARZXY2_3797	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ARZXY2_3798	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ARZXY2_3799	COG0438	transferase activity, transferring glycosyl groups
ARZXY2_3801	COG0859	PFAM glycosyl transferase family 9
ARZXY2_3802	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ARZXY2_3803	COG0859	PFAM glycosyl transferase family 9
ARZXY2_3804	COG1191	sigma factor activity
ARZXY2_3808	COG0561	phosphatase activity
ARZXY2_3809	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ARZXY2_3810	COG1597	lipid kinase activity
ARZXY2_3812	COG0077	Prephenate dehydratase
ARZXY2_3813	COG0425	Belongs to the sulfur carrier protein TusA family
ARZXY2_3813	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ARZXY2_3814	COG3340	Belongs to the peptidase S51 family
ARZXY2_3816	COG3104	oligopeptide transport
ARZXY2_3819	COG0778	Nitroreductase
ARZXY2_3820	COG3415	Transposase
ARZXY2_3820	COG2801	Transposase and inactivated derivatives
ARZXY2_3821	COG2233	PERMEase
ARZXY2_3823	COG3655	Transcriptional regulator
ARZXY2_3825	COG0693	protein deglycase activity
ARZXY2_3827	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ARZXY2_3831	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ARZXY2_3833	COG1929	Belongs to the glycerate kinase type-1 family
ARZXY2_3834	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ARZXY2_3835	COG3250	beta-galactosidase activity
ARZXY2_3836	COG0584	glycerophosphoryl diester phosphodiesterase
ARZXY2_3838	COG0561	phosphatase activity
ARZXY2_3839	COG0435	Glutathione S-transferase
ARZXY2_3843	COG0659	secondary active sulfate transmembrane transporter activity
ARZXY2_3844	COG0277	FAD linked oxidase domain protein
ARZXY2_3845	COG4770	biotin carboxylase activity
ARZXY2_3846	COG1984	allophanate hydrolase subunit 2
ARZXY2_3847	COG0477	Major facilitator Superfamily
ARZXY2_3848	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ARZXY2_3849	COG2186	Transcriptional regulator
ARZXY2_385	COG1205	dead DEAH box helicase
ARZXY2_385	COG1111	helicase
ARZXY2_3852	COG0346	lactoylglutathione lyase activity
ARZXY2_3864	COG1716	ATPase activity
ARZXY2_3865	COG1716	ATPase activity
ARZXY2_3868	COG0768	penicillin binding
ARZXY2_3869	COG0515	serine threonine protein kinase
ARZXY2_3870	COG0515	serine threonine protein kinase
ARZXY2_3873	COG3764	Sortase (surface protein transpeptidase)
ARZXY2_3876	COG1595	DNA-templated transcription, initiation
ARZXY2_3877	COG2169	Transcriptional regulator
ARZXY2_3877	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ARZXY2_3878	COG3145	DNA-N1-methyladenine dioxygenase activity
ARZXY2_3879	COG2818	Glycosylase
ARZXY2_3881	COG0457	Tetratricopeptide repeat
ARZXY2_3881	COG0705	Rhomboid family
ARZXY2_3884	COG1215	transferase activity, transferring glycosyl groups
ARZXY2_3886	COG3525	Glycosyl hydrolase, family 20, catalytic domain
ARZXY2_3886	COG3291	Pkd domain containing protein
ARZXY2_3890	COG3266	domain, Protein
ARZXY2_3892	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ARZXY2_3893	COG0187	DNA topoisomerase II activity
ARZXY2_3894	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
ARZXY2_3895	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ARZXY2_3896	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
ARZXY2_3897	COG0592	DNA-directed DNA polymerase activity
ARZXY2_3898	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ARZXY2_3899	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ARZXY2_390	COG2890	protein-(glutamine-N5) methyltransferase activity
ARZXY2_3900	COG0594	ribonuclease P activity
ARZXY2_3901	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ARZXY2_3902	COG0706	membrane insertase activity
ARZXY2_3904	COG0357	Ribosomal RNA small subunit methyltransferase G
ARZXY2_3905	COG1192	Involved in chromosome partitioning
ARZXY2_3908	COG3118	belongs to the thioredoxin family
ARZXY2_3909	COG0492	ferredoxin-NADP+ reductase activity
ARZXY2_3914	COG0617	tRNA 3'-terminal CCA addition
ARZXY2_3915	COG0406	alpha-ribazole phosphatase activity
ARZXY2_3919	COG2910	NAD(P)H-binding
ARZXY2_3920	COG1733	regulation of RNA biosynthetic process
ARZXY2_3921	COG1136	(ABC) transporter
ARZXY2_3923	COG4585	Histidine kinase
ARZXY2_3924	COG2197	response regulator
ARZXY2_3925	COG0768	penicillin binding
ARZXY2_3927	COG0488	(ABC) transporter
ARZXY2_3928	COG3415	Transposase
ARZXY2_3928	COG2801	Transposase and inactivated derivatives
ARZXY2_393	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ARZXY2_393	COG1754	DNA topoisomerase type I activity
ARZXY2_3930	COG0738	Major facilitator superfamily
ARZXY2_3932	COG1131	(ABC) transporter
ARZXY2_3934	COG4585	Histidine kinase
ARZXY2_3935	COG2197	response regulator
ARZXY2_3936	COG1362	aminopeptidase activity
ARZXY2_3937	COG1113	amino acid transport
ARZXY2_3939	COG0640	Transcriptional regulator
ARZXY2_3942	COG1742	UPF0060 membrane protein
ARZXY2_3943	COG0360	Binds together with S18 to 16S ribosomal RNA
ARZXY2_3945	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ARZXY2_3946	COG0359	binds to the 23S rRNA
ARZXY2_395	COG0248	Ppx GppA phosphatase
ARZXY2_3958	COG0305	Participates in initiation and elongation during chromosome replication
ARZXY2_396	COG1082	Xylose isomerase domain protein TIM barrel
ARZXY2_3961	COG0698	ribose 5-phosphate isomerase
ARZXY2_3962	COG2376	Dihydroxyacetone kinase
ARZXY2_3963	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_3964	COG1082	Xylose isomerase domain protein TIM barrel
ARZXY2_3966	COG3959	Transketolase, thiamine diphosphate binding domain
ARZXY2_3967	COG3958	Transketolase
ARZXY2_397	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ARZXY2_3970	COG1607	acyl-coa hydrolase
ARZXY2_398	COG0569	domain protein
ARZXY2_3981	COG1937	Protein conserved in bacteria
ARZXY2_399	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ARZXY2_3991	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
ARZXY2_3993	COG2610	gluconate transmembrane transporter activity
ARZXY2_40	COG1070	Carbohydrate kinase
ARZXY2_400	COG0123	including yeast histone deacetylase and acetoin utilization protein
ARZXY2_4001	COG0583	DNA-binding transcription factor activity
ARZXY2_4003	COG3384	dioxygenase
ARZXY2_4008	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ARZXY2_4009	COG1116	anion transmembrane transporter activity
ARZXY2_4009	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ARZXY2_4010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ARZXY2_4011	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ARZXY2_4012	COG1116	anion transmembrane transporter activity
ARZXY2_4013	COG1309	transcriptional regulator
ARZXY2_4014	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_4018	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ARZXY2_402	COG0640	Transcriptional regulator
ARZXY2_4028	COG0800	Aldolase
ARZXY2_4029	COG2186	Transcriptional regulator
ARZXY2_403	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ARZXY2_4030	COG1879	ABC-type sugar transport system periplasmic component
ARZXY2_4031	COG1172	Belongs to the binding-protein-dependent transport system permease family
ARZXY2_4032	COG1172	Belongs to the binding-protein-dependent transport system permease family
ARZXY2_4036	COG2376	Dihydroxyacetone kinase
ARZXY2_4037	COG1461	Dihydroxyacetone kinase
ARZXY2_4038	COG0693	protein deglycase activity
ARZXY2_4041	COG4948	Mandelate Racemase Muconate Lactonizing
ARZXY2_4042	COG3386	PFAM SMP-30 Gluconolaconase
ARZXY2_4043	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ARZXY2_4044	COG0693	protein deglycase activity
ARZXY2_4047	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ARZXY2_4052	COG4974	Belongs to the 'phage' integrase family
ARZXY2_4054	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ARZXY2_4056	COG2252	PERMEase
ARZXY2_4060	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ARZXY2_407	COG1609	Transcriptional regulator
ARZXY2_408	COG0673	inositol 2-dehydrogenase activity
ARZXY2_4087	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ARZXY2_4099	COG1802	Transcriptional regulator
ARZXY2_41	COG3347	Dehydrogenase
ARZXY2_41	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_410	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ARZXY2_4100	COG2271	Major facilitator Superfamily
ARZXY2_4101	COG1970	mechanosensitive ion channel activity
ARZXY2_4102	COG0318	PFAM AMP-dependent synthetase and ligase
ARZXY2_4103	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ARZXY2_4103	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ARZXY2_4104	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ARZXY2_4105	COG0509	glycine decarboxylation via glycine cleavage system
ARZXY2_4106	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ARZXY2_4109	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ARZXY2_411	COG4948	Mandelate Racemase Muconate Lactonizing
ARZXY2_4134	COG1846	Transcriptional regulator
ARZXY2_4136	COG0515	serine threonine protein kinase
ARZXY2_4137	COG2261	transglycosylase associated protein
ARZXY2_4140	COG0243	molybdopterin cofactor binding
ARZXY2_4142	COG2814	Major facilitator Superfamily
ARZXY2_4146	COG3387	PFAM Glycoside hydrolase 15-related
ARZXY2_4152	COG2815	serine threonine protein kinase
ARZXY2_4152	COG0515	serine threonine protein kinase
ARZXY2_4155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ARZXY2_4156	COG1621	beta-fructofuranosidase activity
ARZXY2_4158	COG0395	ABC-type sugar transport system, permease component
ARZXY2_4160	COG1653	transport
ARZXY2_4163	COG1621	beta-fructofuranosidase activity
ARZXY2_4166	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_4168	COG2207	Transcriptional regulator
ARZXY2_4168	COG3708	Transcriptional regulator
ARZXY2_417	COG1175	transmembrane transport
ARZXY2_4170	COG2261	transglycosylase associated protein
ARZXY2_4178	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ARZXY2_418	COG0395	ABC-type sugar transport system, permease component
ARZXY2_4181	COG0583	DNA-binding transcription factor activity
ARZXY2_4182	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ARZXY2_4183	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ARZXY2_4184	COG1984	allophanate hydrolase subunit 2
ARZXY2_4185	COG0477	Major facilitator Superfamily
ARZXY2_4186	COG4221	oxidoreductase activity
ARZXY2_4187	COG1607	acyl-coa hydrolase
ARZXY2_4190	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ARZXY2_4193	COG1950	PFAM Membrane protein of
ARZXY2_4194	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ARZXY2_4196	COG0022	dehydrogenase e1 component
ARZXY2_4197	COG0508	dehydrogenase complex catalyzes the overall conversion of
ARZXY2_42	COG4952	isomerase
ARZXY2_4205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ARZXY2_4211	COG1309	transcriptional regulator
ARZXY2_4217	COG0673	inositol 2-dehydrogenase activity
ARZXY2_4223	COG0686	Belongs to the AlaDH PNT family
ARZXY2_4228	COG1793	dna ligase
ARZXY2_423	COG1175	transmembrane transport
ARZXY2_4230	COG2267	carboxylic ester hydrolase activity
ARZXY2_4234	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ARZXY2_4236	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ARZXY2_4236	COG2213	PTS system mannitol-specific
ARZXY2_4237	COG0246	Mannitol dehydrogenase
ARZXY2_4239	COG1113	amino acid transport
ARZXY2_424	COG0395	ABC-type sugar transport system, permease component
ARZXY2_4244	COG1846	Transcriptional regulator
ARZXY2_4245	COG2814	Major facilitator Superfamily
ARZXY2_4246	COG0477	Major facilitator Superfamily
ARZXY2_4247	COG0477	Major facilitator Superfamily
ARZXY2_4248	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ARZXY2_4255	COG1309	transcriptional regulator
ARZXY2_4257	COG0281	malic enzyme
ARZXY2_426	COG2814	Major facilitator Superfamily
ARZXY2_4263	COG1760	l-serine dehydratase
ARZXY2_4268	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ARZXY2_427	COG0673	inositol 2-dehydrogenase activity
ARZXY2_4270	COG0477	Major facilitator Superfamily
ARZXY2_4272	COG1414	Transcriptional regulator
ARZXY2_4277	COG1280	lysine exporter protein (LysE YggA)
ARZXY2_4278	COG1522	sequence-specific DNA binding
ARZXY2_428	COG5578	integral membrane protein
ARZXY2_4281	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ARZXY2_4283	COG4221	oxidoreductase activity
ARZXY2_4284	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ARZXY2_4286	COG2186	Transcriptional regulator
ARZXY2_4288	COG1027	Aspartate ammonia-lyase
ARZXY2_4290	COG2186	Transcriptional regulator
ARZXY2_43	COG3254	rhamnose metabolic process
ARZXY2_430	COG1653	transport
ARZXY2_4303	COG0667	Aldo Keto reductase
ARZXY2_431	COG4209	transmembrane transport
ARZXY2_4314	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ARZXY2_4315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ARZXY2_4316	COG1120	ATPase activity
ARZXY2_432	COG0395	ABC-type sugar transport system, permease component
ARZXY2_4321	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ARZXY2_4322	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ARZXY2_4323	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ARZXY2_433	COG2755	lipolytic protein G-D-S-L family
ARZXY2_4338	COG2814	Major facilitator Superfamily
ARZXY2_4344	COG0745	RESPONSE REGULATOR receiver
ARZXY2_4345	COG0745	RESPONSE REGULATOR receiver
ARZXY2_4347	COG5002	protein histidine kinase activity
ARZXY2_4349	COG2814	Major facilitator Superfamily
ARZXY2_435	COG3458	cephalosporin-C deacetylase activity
ARZXY2_4350	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ARZXY2_4351	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ARZXY2_4352	COG4948	Mandelate Racemase Muconate Lactonizing
ARZXY2_4353	COG0588	phosphoglycerate mutase activity
ARZXY2_4357	COG3547	Transposase (IS116 IS110 IS902 family)
ARZXY2_4358	COG1321	iron dependent repressor
ARZXY2_436	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ARZXY2_4363	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ARZXY2_4364	COG0785	Cytochrome C biogenesis protein
ARZXY2_4368	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ARZXY2_4370	COG0739	heme binding
ARZXY2_4375	COG0640	Transcriptional regulator
ARZXY2_4376	COG3336	cytochrome c oxidase
ARZXY2_4381	COG2372	response to copper ion
ARZXY2_4384	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ARZXY2_44	COG1609	Transcriptional regulator
ARZXY2_440	COG0560	Phosphoserine phosphatase
ARZXY2_4401	COG2323	membrane
ARZXY2_4402	COG4325	translation initiation factor activity
ARZXY2_442	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ARZXY2_4430	COG1192	Involved in chromosome partitioning
ARZXY2_4446	COG0789	Transcriptional regulator
ARZXY2_4453	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ARZXY2_4454	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ARZXY2_4455	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ARZXY2_4456	COG1802	Transcriptional regulator
ARZXY2_4458	COG1556	Lactate utilization protein
ARZXY2_4459	COG1139	Iron-sulfur cluster binding protein
ARZXY2_446	COG0406	alpha-ribazole phosphatase activity
ARZXY2_4460	COG0247	lactate metabolic process
ARZXY2_4461	COG1620	l-lactate permease
ARZXY2_4462	COG2186	Transcriptional regulator
ARZXY2_4471	COG1475	DNA binding
ARZXY2_448	COG0785	Cytochrome C biogenesis protein
ARZXY2_4499	COG2963	transposase activity
ARZXY2_45	COG2017	converts alpha-aldose to the beta-anomer
ARZXY2_450	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ARZXY2_451	COG0443	Heat shock 70 kDa protein
ARZXY2_4548	COG2963	transposase activity
ARZXY2_4569	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ARZXY2_4569	COG3608	succinylglutamate desuccinylase aspartoacylase
ARZXY2_4574	COG3328	transposase activity
ARZXY2_4584	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ARZXY2_4587	COG0179	Fumarylacetoacetate (FAA) hydrolase
ARZXY2_4597	COG4974	Belongs to the 'phage' integrase family
ARZXY2_46	COG2160	L-arabinose isomerase activity
ARZXY2_4601	COG2963	transposase activity
ARZXY2_4604	COG2271	Major facilitator Superfamily
ARZXY2_4605	COG1802	Transcriptional regulator
ARZXY2_461	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ARZXY2_4611	COG3842	ATPase activity
ARZXY2_4614	COG0586	Pfam SNARE associated Golgi protein
ARZXY2_4615	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ARZXY2_4617	COG0745	RESPONSE REGULATOR receiver
ARZXY2_4618	COG2205	protein histidine kinase activity
ARZXY2_4624	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ARZXY2_4627	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ARZXY2_4628	COG0586	Pfam SNARE associated Golgi protein
ARZXY2_463	COG1266	CAAX protease self-immunity
ARZXY2_4630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ARZXY2_4631	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ARZXY2_4634	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ARZXY2_4635	COG1937	Protein conserved in bacteria
ARZXY2_464	COG0803	Belongs to the bacterial solute-binding protein 9 family
ARZXY2_4646	COG0640	Transcriptional regulator
ARZXY2_4647	COG2814	Major facilitator Superfamily
ARZXY2_4649	COG0640	Transcriptional regulator
ARZXY2_465	COG1121	(ABC) transporter
ARZXY2_4650	COG2217	Heavy metal translocating P-type atpase
ARZXY2_4657	COG2217	Heavy metal translocating P-type atpase
ARZXY2_466	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ARZXY2_4667	COG2132	Multicopper oxidase
ARZXY2_4668	COG0785	Cytochrome C biogenesis protein
ARZXY2_467	COG0488	(ABC) transporter
ARZXY2_4676	COG2124	cytochrome p450
ARZXY2_4677	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ARZXY2_4678	COG1028	Short-chain dehydrogenase reductase Sdr
ARZXY2_4680	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ARZXY2_4683	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ARZXY2_4687	COG1473	amidohydrolase
ARZXY2_4688	COG2814	Major facilitator Superfamily
ARZXY2_4693	COG2149	membrane
ARZXY2_4703	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ARZXY2_4705	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ARZXY2_473	COG0183	Belongs to the thiolase family
ARZXY2_4731	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ARZXY2_474	COG1024	Enoyl-CoA hydratase
ARZXY2_475	COG1250	3-hydroxyacyl-CoA dehydrogenase
ARZXY2_4758	COG2066	Belongs to the glutaminase family
ARZXY2_4762	COG0765	amino acid transport
ARZXY2_4765	COG1609	Transcriptional regulator
ARZXY2_4771	COG0789	Transcriptional regulator
ARZXY2_4772	COG1482	cell wall glycoprotein biosynthetic process
ARZXY2_4774	COG0589	response to stress
ARZXY2_478	COG1216	Glycosyl transferase, family 2
ARZXY2_4784	COG1609	Transcriptional regulator
ARZXY2_4791	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ARZXY2_4794	COG0686	Belongs to the AlaDH PNT family
ARZXY2_4798	COG0512	Glutamine amidotransferase of anthranilate synthase
ARZXY2_480	COG2030	dehydratase
ARZXY2_480	COG1012	belongs to the aldehyde dehydrogenase family
ARZXY2_4819	COG1192	Involved in chromosome partitioning
ARZXY2_4829	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ARZXY2_4839	COG1401	restriction endodeoxyribonuclease activity
ARZXY2_484	COG2050	protein possibly involved in aromatic compounds catabolism
ARZXY2_4850	COG4124	Belongs to the glycosyl hydrolase 26 family
ARZXY2_4853	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ARZXY2_4862	COG1475	DNA binding
ARZXY2_4867	COG2175	clavaminate synthase activity
ARZXY2_4870	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ARZXY2_4886	COG1192	Involved in chromosome partitioning
ARZXY2_489	COG5002	protein histidine kinase activity
ARZXY2_4895	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ARZXY2_49	COG1609	Transcriptional regulator
ARZXY2_4902	COG0529	Catalyzes the synthesis of activated sulfate
ARZXY2_4914	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ARZXY2_493	COG3706	GGDEF domain
ARZXY2_493	COG2203	Gaf domain
ARZXY2_493	COG5001	Diguanylate cyclase
ARZXY2_493	COG4251	negative regulation of phosphorylation
ARZXY2_494	COG5002	protein histidine kinase activity
ARZXY2_494	COG2205	protein histidine kinase activity
ARZXY2_494	COG0784	Response regulator, receiver
ARZXY2_495	COG3942	CHAP domain
ARZXY2_495	COG1388	LysM domain
ARZXY2_496	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ARZXY2_497	COG3396	Phenylacetate-CoA oxygenase
ARZXY2_498	COG3460	Phenylacetate-CoA oxygenase
ARZXY2_499	COG3396	Phenylacetate-CoA oxygenase
ARZXY2_50	COG1070	Carbohydrate kinase
ARZXY2_500	COG2151	metal-sulfur cluster biosynthetic enzyme
ARZXY2_501	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ARZXY2_502	COG1024	Enoyl-CoA hydratase
ARZXY2_505	COG2801	Transposase and inactivated derivatives
ARZXY2_505	COG3415	Transposase
ARZXY2_506	COG1597	lipid kinase activity
ARZXY2_51	COG2115	Belongs to the xylose isomerase family
ARZXY2_511	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ARZXY2_512	COG3979	chitinase
ARZXY2_518	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ARZXY2_520	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ARZXY2_521	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
ARZXY2_533	COG0489	protein tyrosine kinase activity
ARZXY2_537	COG1316	TRANSCRIPTIONal
ARZXY2_541	COG0438	transferase activity, transferring glycosyl groups
ARZXY2_542	COG1682	transport, permease protein
ARZXY2_543	COG1134	teichoic acid transport
ARZXY2_545	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ARZXY2_552	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ARZXY2_556	COG0022	dehydrogenase e1 component
ARZXY2_557	COG0508	dehydrogenase complex catalyzes the overall conversion of
ARZXY2_56	COG0673	inositol 2-dehydrogenase activity
ARZXY2_561	COG1404	Belongs to the peptidase S8 family
ARZXY2_569	COG1175	transmembrane transport
ARZXY2_570	COG0395	ABC-type sugar transport system, permease component
ARZXY2_571	COG1621	beta-fructofuranosidase activity
ARZXY2_572	COG1609	Transcriptional regulator
ARZXY2_575	COG4948	Mandelate Racemase Muconate Lactonizing
ARZXY2_577	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ARZXY2_579	COG0765	amino acid transport
ARZXY2_58	COG1609	Transcriptional regulator
ARZXY2_581	COG1169	isochorismate synthase
ARZXY2_582	COG2226	methyltransferase
ARZXY2_589	COG2860	membrane
ARZXY2_591	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ARZXY2_592	COG0175	sulfate reduction
ARZXY2_594	COG2895	sulfate adenylyltransferase (ATP) activity
ARZXY2_595	COG2040	homocysteine
ARZXY2_597	COG1116	anion transmembrane transporter activity
ARZXY2_597	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ARZXY2_598	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ARZXY2_60	COG0583	DNA-binding transcription factor activity
ARZXY2_601	COG1733	regulation of RNA biosynthetic process
ARZXY2_603	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ARZXY2_604	COG1648	precorrin-2 dehydrogenase activity
ARZXY2_604	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ARZXY2_606	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ARZXY2_606	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ARZXY2_607	COG2186	Transcriptional regulator
ARZXY2_609	COG2807	transmembrane transport
ARZXY2_610	COG3835	regulator
ARZXY2_611	COG1012	belongs to the aldehyde dehydrogenase family
ARZXY2_618	COG0531	amino acid
ARZXY2_625	COG0501	Belongs to the peptidase M48B family
ARZXY2_626	COG1666	GTP binding
ARZXY2_629	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ARZXY2_633	COG1131	(ABC) transporter
ARZXY2_636	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ARZXY2_642	COG1051	belongs to the nudix hydrolase family
ARZXY2_646	COG0395	ABC-type sugar transport system, permease component
ARZXY2_652	COG0754	glutathionylspermidine amidase activity
ARZXY2_661	COG0702	epimerase
ARZXY2_663	COG1940	carbohydrate kinase activity
ARZXY2_667	COG0366	Alpha amylase catalytic
ARZXY2_668	COG4989	oxidoreductase activity
ARZXY2_670	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ARZXY2_675	COG2030	dehydratase
ARZXY2_677	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ARZXY2_68	COG0717	Belongs to the dCTP deaminase family
ARZXY2_680	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ARZXY2_682	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ARZXY2_683	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ARZXY2_684	COG1725	Transcriptional regulator
ARZXY2_687	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ARZXY2_688	COG0456	acetyltransferase
ARZXY2_689	COG0745	RESPONSE REGULATOR receiver
ARZXY2_692	COG3485	protocatechuate 3,4-dioxygenase
ARZXY2_694	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ARZXY2_70	COG0475	glutathione-regulated potassium exporter activity
ARZXY2_704	COG2197	response regulator
ARZXY2_705	COG0436	Aminotransferase
ARZXY2_707	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ARZXY2_709	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ARZXY2_710	COG0081	regulation of translation
ARZXY2_713	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ARZXY2_714	COG0222	ribosome binding
ARZXY2_715	COG0442	prolyl-tRNA aminoacylation
ARZXY2_716	COG0183	Belongs to the thiolase family
ARZXY2_717	COG0085	RNA polymerase activity
ARZXY2_718	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ARZXY2_719	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ARZXY2_720	COG0049	tRNA binding
ARZXY2_721	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ARZXY2_722	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ARZXY2_726	COG0051	transcription antitermination factor activity, RNA binding
ARZXY2_727	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ARZXY2_728	COG0088	Forms part of the polypeptide exit tunnel
ARZXY2_729	COG0089	rRNA binding
ARZXY2_73	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ARZXY2_73	COG2111	Na H antiporter
ARZXY2_730	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ARZXY2_731	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ARZXY2_732	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ARZXY2_733	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ARZXY2_734	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ARZXY2_735	COG0255	Belongs to the universal ribosomal protein uL29 family
ARZXY2_736	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ARZXY2_737	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ARZXY2_738	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ARZXY2_739	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ARZXY2_740	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ARZXY2_741	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ARZXY2_743	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ARZXY2_744	COG1841	ribosomal large subunit assembly
ARZXY2_745	COG0200	Binds to the 23S rRNA
ARZXY2_747	COG0563	adenylate kinase activity
ARZXY2_748	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ARZXY2_749	COG1216	Glycosyl transferase, family 2
ARZXY2_749	COG1442	glycosyl transferase family 8
ARZXY2_751	COG0318	PFAM AMP-dependent synthetase and ligase
ARZXY2_753	COG0024	Methionine aminopeptidase
ARZXY2_757	COG3191	aminopeptidase activity
ARZXY2_758	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ARZXY2_759	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ARZXY2_760	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ARZXY2_761	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ARZXY2_762	COG0202	RNA polymerase activity
ARZXY2_763	COG0203	ribosomal protein L17
ARZXY2_764	COG0101	tRNA pseudouridine synthase activity
ARZXY2_768	COG0455	bacterial-type flagellum organization
ARZXY2_77	COG2212	antiporter activity
ARZXY2_774	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ARZXY2_775	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ARZXY2_776	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ARZXY2_778	COG1072	(Pantothenic acid kinase))
ARZXY2_78	COG1320	monovalent cation:proton antiporter activity
ARZXY2_780	COG0736	holo-[acyl-carrier-protein] synthase activity
ARZXY2_785	COG0667	Aldo Keto reductase
ARZXY2_787	COG2759	Belongs to the formate--tetrahydrofolate ligase family
ARZXY2_789	COG0438	transferase activity, transferring glycosyl groups
ARZXY2_791	COG1486	melibiose metabolic process
ARZXY2_793	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ARZXY2_794	COG0802	atpase or kinase
ARZXY2_797	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ARZXY2_798	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ARZXY2_8	COG0776	regulation of translation
ARZXY2_801	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ARZXY2_802	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ARZXY2_805	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ARZXY2_806	COG0459	protein refolding
ARZXY2_81	COG4721	ABC-type cobalt transport system, permease component
ARZXY2_811	COG0516	GMP reductase activity
ARZXY2_815	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ARZXY2_819	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ARZXY2_819	COG0519	Catalyzes the synthesis of GMP from XMP
ARZXY2_82	COG1122	ATPase activity
ARZXY2_820	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
ARZXY2_823	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ARZXY2_824	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ARZXY2_830	COG1695	Transcriptional regulator
ARZXY2_831	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ARZXY2_833	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ARZXY2_834	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ARZXY2_835	COG1528	Iron-storage protein
ARZXY2_836	COG0598	Magnesium transport protein CorA
ARZXY2_841	COG3548	integral membrane protein
ARZXY2_842	COG2814	Major facilitator Superfamily
ARZXY2_843	COG2814	Major facilitator Superfamily
ARZXY2_845	COG2971	BadF BadG BcrA BcrD
ARZXY2_848	COG1162	GTPase activity
ARZXY2_850	COG1174	glycine betaine transport
ARZXY2_854	COG2326	polyphosphate kinase activity
ARZXY2_855	COG1722	exodeoxyribonuclease VII activity
ARZXY2_856	COG1570	exodeoxyribonuclease VII activity
ARZXY2_859	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ARZXY2_860	COG1322	Protein conserved in bacteria
ARZXY2_861	COG0012	GTP binding
ARZXY2_87	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ARZXY2_877	COG0747	negative chemotaxis
ARZXY2_879	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ARZXY2_89	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ARZXY2_891	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ARZXY2_892	COG3226	Transcriptional regulator
ARZXY2_895	COG2171	N-acyltransferase activity
ARZXY2_896	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ARZXY2_897	COG0765	amino acid transport
ARZXY2_899	COG0765	amino acid transport
ARZXY2_900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ARZXY2_901	COG1126	abc transporter atp-binding protein
ARZXY2_906	COG4122	O-methyltransferase activity
ARZXY2_907	COG1595	DNA-templated transcription, initiation
ARZXY2_909	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ARZXY2_912	COG2239	Acts as a magnesium transporter
ARZXY2_914	COG0006	proline dipeptidase activity
ARZXY2_915	COG0613	PHP domain protein
ARZXY2_916	COG2095	MarC family integral membrane protein
ARZXY2_917	COG0513	Belongs to the DEAD box helicase family
ARZXY2_918	COG2801	Transposase and inactivated derivatives
ARZXY2_918	COG3415	Transposase
ARZXY2_921	COG0352	thiamine-phosphate diphosphorylase activity
ARZXY2_927	COG1309	transcriptional regulator
ARZXY2_929	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ARZXY2_930	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ARZXY2_934	COG0181	hydroxymethylbilane synthase activity
ARZXY2_936	COG0113	porphobilinogen synthase activity
ARZXY2_938	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ARZXY2_940	COG1472	Belongs to the glycosyl hydrolase 3 family
ARZXY2_942	COG0765	amino acid transport
ARZXY2_943	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ARZXY2_946	COG1074	ATP-dependent DNA helicase activity
ARZXY2_949	COG2816	NAD+ diphosphatase activity
ARZXY2_95	COG2986	histidine ammonia-lyase
ARZXY2_953	COG3480	Lon protease (S16) C-terminal proteolytic domain
ARZXY2_954	COG1615	UPF0182 protein
ARZXY2_958	COG1842	Phage shock protein A
ARZXY2_960	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ARZXY2_962	COG2086	electron transfer activity
ARZXY2_963	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ARZXY2_964	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ARZXY2_965	COG3265	gluconokinase activity
ARZXY2_967	COG1595	DNA-templated transcription, initiation
ARZXY2_968	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ARZXY2_969	COG0484	heat shock protein binding
ARZXY2_97	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ARZXY2_975	COG0482	sulfurtransferase activity
ARZXY2_979	COG0601	transmembrane transport
ARZXY2_98	COG0833	amino acid
ARZXY2_980	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ARZXY2_986	COG0714	Associated with various cellular activities
ARZXY2_990	COG0745	RESPONSE REGULATOR receiver
ARZXY2_991	COG5002	protein histidine kinase activity
ARZXY2_991	COG5000	phosphorelay sensor kinase activity
ARZXY2_992	COG5401	PFAM Sporulation and spore germination
ARZXY2_994	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ARZXY2_995	COG3214	Protein conserved in bacteria
ARZXY2_996	COG0653	protein targeting