locus-tag	class	description
NF551_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NF551_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NF551_00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
NF551_00030	COG0187	DNA topoisomerase II activity
NF551_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NF551_00075	COG0705	Rhomboid family
NF551_00085	COG3764	Sortase (surface protein transpeptidase)
NF551_00100	COG0515	serine threonine protein kinase
NF551_00100	COG2815	serine threonine protein kinase
NF551_00105	COG0515	serine threonine protein kinase
NF551_00110	COG0768	penicillin binding
NF551_00125	COG1716	ATPase activity
NF551_00130	COG1716	ATPase activity
NF551_00155	COG0783	Belongs to the Dps family
NF551_00200	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NF551_00210	COG0789	Transcriptional regulator
NF551_00235	COG2267	carboxylic ester hydrolase activity
NF551_00250	COG1376	ErfK ybiS ycfS ynhG family protein
NF551_00255	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NF551_00255	COG2755	lipolytic protein G-D-S-L family
NF551_00260	COG0702	epimerase
NF551_00280	COG1028	Short-chain dehydrogenase reductase Sdr
NF551_00295	COG0596	Alpha beta hydrolase
NF551_00305	COG0561	phosphatase activity
NF551_00310	COG0671	phosphoesterase, PA-phosphatase related
NF551_00320	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NF551_00335	COG1929	Belongs to the glycerate kinase type-1 family
NF551_00340	COG2233	PERMEase
NF551_00345	COG1028	Short-chain dehydrogenase reductase Sdr
NF551_00350	COG1012	belongs to the aldehyde dehydrogenase family
NF551_00360	COG1116	anion transmembrane transporter activity
NF551_00360	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NF551_00380	COG3104	oligopeptide transport
NF551_00385	COG0154	amidase activity
NF551_00390	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NF551_00395	COG0077	Prephenate dehydratase
NF551_00410	COG1597	lipid kinase activity
NF551_00415	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NF551_00420	COG0561	phosphatase activity
NF551_00430	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NF551_00435	COG2027	D-alanyl-D-alanine carboxypeptidase
NF551_00445	COG0037	tRNA processing
NF551_00455	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NF551_00460	COG0302	gtp cyclohydrolase
NF551_00470	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NF551_00475	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NF551_00500	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NF551_00505	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NF551_00525	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
NF551_00535	COG2376	Dihydroxyacetone kinase
NF551_00540	COG1461	Dihydroxyacetone kinase
NF551_00545	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NF551_00545	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NF551_00545	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
NF551_00560	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NF551_00590	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NF551_00595	COG0306	phosphate transporter
NF551_00640	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NF551_00640	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NF551_00645	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NF551_00650	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NF551_00650	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NF551_00650	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NF551_00665	COG2261	transglycosylase associated protein
NF551_00675	COG2733	membrane
NF551_00685	COG3387	PFAM Glycoside hydrolase 15-related
NF551_00705	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NF551_00710	COG0857	belongs to the CobB CobQ family
NF551_00710	COG0280	phosphate acetyltransferase
NF551_00715	COG0531	amino acid
NF551_00730	COG2252	PERMEase
NF551_00765	COG0477	Major facilitator Superfamily
NF551_00810	COG1414	Transcriptional regulator
NF551_00825	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NF551_00830	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NF551_00850	COG0191	fructose-bisphosphate aldolase activity
NF551_00870	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NF551_00910	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NF551_00930	COG1832	CoA-binding protein
NF551_00945	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NF551_00950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NF551_00960	COG1116	anion transmembrane transporter activity
NF551_00975	COG1028	Short-chain dehydrogenase reductase Sdr
NF551_00990	COG1832	CoA-binding protein
NF551_01000	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NF551_01005	COG2011	ABC-type metal ion transport system permease component
NF551_01020	COG1464	Belongs to the NlpA lipoprotein family
NF551_01050	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NF551_01055	COG0047	phosphoribosylformylglycinamidine synthase activity
NF551_01060	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NF551_01085	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NF551_01090	COG1846	Transcriptional regulator
NF551_01110	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NF551_01150	COG3548	integral membrane protein
NF551_01165	COG1136	(ABC) transporter
NF551_01175	COG2197	response regulator
NF551_01180	COG1309	transcriptional regulator
NF551_01195	COG0318	PFAM AMP-dependent synthetase and ligase
NF551_01200	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NF551_01205	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NF551_01205	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NF551_01280	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NF551_01295	COG0765	amino acid transport
NF551_01330	COG0028	Belongs to the TPP enzyme family
NF551_01340	COG0579	oxidoreductase
NF551_01350	COG0531	amino acid
NF551_01365	COG1028	Short-chain dehydrogenase reductase Sdr
NF551_01400	COG1960	acyl-CoA dehydrogenase activity
NF551_01425	COG1063	alcohol dehydrogenase
NF551_01440	COG0583	DNA-binding transcription factor activity
NF551_01445	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
NF551_01450	COG1126	abc transporter atp-binding protein
NF551_01455	COG0765	amino acid transport
NF551_01495	COG0363	glucosamine-6-phosphate deaminase activity
NF551_01545	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NF551_01580	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NF551_01590	COG1396	sequence-specific DNA binding
NF551_01595	COG0024	Methionine aminopeptidase
NF551_01605	COG1595	DNA-templated transcription, initiation
NF551_01610	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NF551_01620	COG0179	Fumarylacetoacetate (FAA) hydrolase
NF551_01630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NF551_01640	COG0179	Fumarylacetoacetate (FAA) hydrolase
NF551_01645	COG0583	DNA-binding transcription factor activity
NF551_01650	COG1172	Belongs to the binding-protein-dependent transport system permease family
NF551_01655	COG1129	ABC transporter
NF551_01665	COG1404	Belongs to the peptidase S8 family
NF551_01690	COG0351	phosphomethylpyrimidine kinase
NF551_01710	COG0343	queuine tRNA-ribosyltransferase activity
NF551_01765	COG0564	pseudouridine synthase activity
NF551_01770	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NF551_01775	COG1201	RNA secondary structure unwinding
NF551_01790	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NF551_01800	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NF551_01815	COG2354	Protein conserved in bacteria
NF551_01835	COG4589	Belongs to the CDS family
NF551_01855	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NF551_01865	COG2062	phosphohistidine phosphatase, SixA
NF551_01880	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
NF551_01940	COG1024	Enoyl-CoA hydratase
NF551_01955	COG0667	Aldo Keto reductase
NF551_01965	COG1505	serine-type exopeptidase activity
NF551_01970	COG2860	membrane
NF551_01980	COG2197	response regulator
NF551_01985	COG4585	Histidine kinase
NF551_02025	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
NF551_02030	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NF551_02035	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NF551_02065	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NF551_02080	COG1228	amidohydrolase
NF551_02105	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NF551_02140	COG1966	Carbon starvation protein
NF551_02160	COG0656	L-ascorbic acid biosynthetic process
NF551_02165	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NF551_02175	COG1256	bacterial-type flagellum assembly
NF551_02175	COG4786	Flagellar basal body rod
NF551_02190	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NF551_02195	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NF551_02200	COG1516	flagellar protein fliS
NF551_02210	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NF551_02225	COG1677	Flagellar hook-basal body complex protein FliE
NF551_02230	COG1766	The M ring may be actively involved in energy transduction
NF551_02235	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NF551_02245	COG1157	protein secretion by the type III secretion system
NF551_02255	COG3883	PFAM NLP P60 protein
NF551_02255	COG0791	NLP P60 protein
NF551_02265	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
NF551_02280	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NF551_02285	COG1360	Flagellar Motor Protein
NF551_02295	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NF551_02295	COG1776	CheC inhibitor of MCP methylation
NF551_02305	COG1338	Plays a role in the flagellum-specific transport system
NF551_02320	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NF551_02325	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NF551_02335	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NF551_02365	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NF551_02370	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NF551_02390	COG0588	phosphoglycerate mutase activity
NF551_02400	COG5002	protein histidine kinase activity
NF551_02405	COG0745	RESPONSE REGULATOR receiver
NF551_02420	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NF551_02425	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NF551_02430	COG0215	cysteine-tRNA ligase activity
NF551_02435	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NF551_02450	COG0366	Alpha amylase catalytic
NF551_02455	COG0366	Alpha amylase catalytic
NF551_02460	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NF551_02505	COG0277	FAD linked oxidase domain protein
NF551_02510	COG0366	Alpha amylase catalytic
NF551_02525	COG3842	ATPase activity
NF551_02530	COG1877	trehalose-phosphatase activity
NF551_02565	COG3655	Transcriptional regulator
NF551_02580	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NF551_02585	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NF551_02600	COG1335	isochorismatase
NF551_02625	COG2159	amidohydrolase
NF551_02655	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NF551_02655	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NF551_02695	COG1609	Transcriptional regulator
NF551_02700	COG0366	Alpha amylase catalytic
NF551_02710	COG1175	transmembrane transport
NF551_02715	COG3833	ABC-type maltose transport systems, permease component
NF551_02720	COG0667	Aldo Keto reductase
NF551_02775	COG1278	Cold shock
NF551_02785	COG0459	protein refolding
NF551_02795	COG2205	protein histidine kinase activity
NF551_02800	COG0745	RESPONSE REGULATOR receiver
NF551_02845	COG1278	Cold shock
NF551_02870	COG0739	heme binding
NF551_02870	COG0741	lytic transglycosylase activity
NF551_02870	COG1196	nuclear chromosome segregation
NF551_02880	COG0791	NLP P60 protein
NF551_02880	COG1388	LysM domain
NF551_02880	COG3103	Sh3 type 3 domain protein
NF551_02890	COG0746	molybdenum cofactor guanylyltransferase activity
NF551_02900	COG0303	'Molybdopterin
NF551_02910	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NF551_02915	COG5002	protein histidine kinase activity
NF551_02920	COG1132	(ABC) transporter
NF551_02930	COG0191	fructose-bisphosphate aldolase activity
NF551_02935	COG1105	Belongs to the carbohydrate kinase PfkB family
NF551_02940	COG1940	carbohydrate kinase activity
NF551_02985	COG0483	inositol monophosphate 1-phosphatase activity
NF551_02995	COG0045	succinate-CoA ligase (ADP-forming) activity
NF551_03005	COG2814	Major facilitator Superfamily
NF551_03020	COG1063	alcohol dehydrogenase
NF551_03040	COG0318	PFAM AMP-dependent synthetase and ligase
NF551_03050	COG1396	sequence-specific DNA binding
NF551_03070	COG0028	Belongs to the TPP enzyme family
NF551_03090	COG3424	synthase
NF551_03125	COG0028	Belongs to the TPP enzyme family
NF551_03140	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NF551_03150	COG0252	asparaginase activity
NF551_03175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NF551_03180	COG1957	nucleoside hydrolase
NF551_03190	COG0431	NADPH-dependent FMN reductase
NF551_03195	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
NF551_03200	COG0028	Belongs to the TPP enzyme family
NF551_03215	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NF551_03240	COG3265	gluconokinase activity
NF551_03245	COG2610	gluconate transmembrane transporter activity
NF551_03250	COG1028	Short-chain dehydrogenase reductase Sdr
NF551_03255	COG1063	alcohol dehydrogenase
NF551_03295	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NF551_03300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NF551_03340	COG0640	Transcriptional regulator
NF551_03360	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NF551_03390	COG4213	ABC transporter substrate-binding protein
NF551_03395	COG1129	ABC transporter
NF551_03400	COG4214	carbohydrate transport
NF551_03410	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NF551_03415	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NF551_03430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NF551_03435	COG4172	Belongs to the ABC transporter superfamily
NF551_03440	COG1619	proteins homologs of microcin C7 resistance protein MccF
NF551_03445	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NF551_03455	COG4948	Mandelate Racemase Muconate Lactonizing
NF551_03500	COG1802	Transcriptional regulator
NF551_03550	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NF551_03565	COG0154	amidase activity
NF551_03570	COG2957	Belongs to the agmatine deiminase family
NF551_03575	COG1228	amidohydrolase
NF551_03600	COG0697	spore germination
NF551_03605	COG1846	Transcriptional regulator
NF551_03615	COG0737	Belongs to the 5'-nucleotidase family
NF551_03630	COG1063	alcohol dehydrogenase
NF551_03635	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NF551_03635	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
NF551_03640	COG1940	carbohydrate kinase activity
NF551_03645	COG2115	Belongs to the xylose isomerase family
NF551_03650	COG1070	Carbohydrate kinase
NF551_03655	COG2017	converts alpha-aldose to the beta-anomer
NF551_03660	COG1175	transmembrane transport
NF551_03675	COG1063	alcohol dehydrogenase
NF551_03700	COG3458	cephalosporin-C deacetylase activity
NF551_03705	COG1472	Belongs to the glycosyl hydrolase 3 family
NF551_03715	COG1175	transmembrane transport
NF551_03720	COG1653	transport
NF551_03725	COG1609	Transcriptional regulator
NF551_03730	COG2814	Major facilitator Superfamily
NF551_03770	COG0583	DNA-binding transcription factor activity
NF551_03780	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NF551_03785	COG0154	amidase activity
NF551_03790	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NF551_03800	COG0667	Aldo Keto reductase
NF551_03805	COG1012	belongs to the aldehyde dehydrogenase family
NF551_03815	COG0363	glucosamine-6-phosphate deaminase activity
NF551_03825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NF551_03830	COG0165	Argininosuccinate lyase
NF551_03835	COG4149	molybdate abc transporter
NF551_03840	COG3842	ATPase activity
NF551_03845	COG1840	ABC-type Fe3 transport system, periplasmic component
NF551_03850	COG1940	carbohydrate kinase activity
NF551_03865	COG0477	Major facilitator Superfamily
NF551_03880	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NF551_03905	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NF551_03910	COG0277	FAD linked oxidase domain protein
NF551_03915	COG2197	response regulator
NF551_03925	COG2188	Transcriptional regulator
NF551_03930	COG1620	l-lactate permease
NF551_03935	COG0247	lactate metabolic process
NF551_03940	COG1139	Iron-sulfur cluster binding protein
NF551_03945	COG1556	Lactate utilization protein
NF551_03950	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NF551_03960	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NF551_03975	COG3971	2-oxopent-4-enoate hydratase activity
NF551_04005	COG0683	leucine binding
NF551_04010	COG1620	l-lactate permease
NF551_04020	COG3619	membrane
NF551_04025	COG0405	Gamma-glutamyltransferase
NF551_04035	COG0039	L-malate dehydrogenase activity
NF551_04055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NF551_04080	COG1063	alcohol dehydrogenase
NF551_04085	COG1131	(ABC) transporter
NF551_04090	COG3559	Exporter of polyketide antibiotics
NF551_04095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NF551_04100	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NF551_04115	COG3842	ATPase activity
NF551_04120	COG1176	ABC-type spermidine putrescine transport system, permease component I
NF551_04125	COG1177	transmembrane transport
NF551_04140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NF551_04155	COG1278	Cold shock
NF551_04160	COG2066	Belongs to the glutaminase family
NF551_04160	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
NF551_04165	COG1278	Cold shock
NF551_04175	COG0515	serine threonine protein kinase
NF551_04180	COG3012	SEC-C Motif Domain Protein
NF551_04185	COG1063	alcohol dehydrogenase
NF551_04195	COG0829	nickel cation binding
NF551_04200	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NF551_04210	COG0804	urea catabolic process
NF551_04215	COG0832	Belongs to the urease beta subunit family
NF551_04220	COG0831	urea catabolic process
NF551_04230	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NF551_04240	COG0753	catalase activity
NF551_04255	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NF551_04265	COG0531	amino acid
NF551_04270	COG2186	Transcriptional regulator
NF551_04330	COG0477	Major facilitator Superfamily
NF551_04335	COG0138	bifunctional purine biosynthesis protein purh
NF551_04365	COG4213	ABC transporter substrate-binding protein
NF551_04370	COG4214	carbohydrate transport
NF551_04375	COG1129	ABC transporter
NF551_04400	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NF551_04405	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NF551_04410	COG1131	(ABC) transporter
NF551_04425	COG2197	response regulator
NF551_04455	COG0180	Tryptophanyl-tRNA synthetase
NF551_04470	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NF551_04485	COG2009	succinate dehydrogenase
NF551_04495	COG1473	amidohydrolase
NF551_04495	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NF551_04500	COG1744	ABC transporter substrate-binding protein PnrA-like
NF551_04505	COG3845	ABC transporter
NF551_04510	COG4603	Belongs to the binding-protein-dependent transport system permease family
NF551_04515	COG1079	Belongs to the binding-protein-dependent transport system permease family
NF551_04535	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NF551_04545	COG0148	phosphopyruvate hydratase activity
NF551_04600	COG0559	Belongs to the binding-protein-dependent transport system permease family
NF551_04615	COG2017	converts alpha-aldose to the beta-anomer
NF551_04625	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NF551_04630	COG0705	Rhomboid family
NF551_04635	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NF551_04645	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NF551_04655	COG1331	Highly conserved protein containing a thioredoxin domain
NF551_04665	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NF551_04675	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NF551_04700	COG0114	fumarate hydratase activity
NF551_04715	COG1494	fructose-1,6-bisphosphatase
NF551_04730	COG1482	cell wall glycoprotein biosynthetic process
NF551_04735	COG1316	TRANSCRIPTIONal
NF551_04790	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NF551_04840	COG0714	Associated with various cellular activities
NF551_04845	COG0084	hydrolase, TatD family'
NF551_04865	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NF551_04870	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NF551_04875	COG0488	(ABC) transporter
NF551_04895	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NF551_04900	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NF551_04905	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NF551_04910	COG0193	aminoacyl-tRNA hydrolase activity
NF551_04925	COG0673	inositol 2-dehydrogenase activity
NF551_04930	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NF551_04935	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NF551_04945	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NF551_04950	COG2244	polysaccharide biosynthetic process
NF551_05030	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NF551_05040	COG0822	iron-sulfur transferase activity
NF551_05045	COG5002	protein histidine kinase activity
NF551_05050	COG0745	RESPONSE REGULATOR receiver
NF551_05060	COG1012	belongs to the aldehyde dehydrogenase family
NF551_05095	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NF551_05130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NF551_05135	COG1012	belongs to the aldehyde dehydrogenase family
NF551_05140	COG1819	glycosyl
NF551_05150	COG3842	ATPase activity
NF551_05155	COG1177	transmembrane transport
NF551_05190	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NF551_05215	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NF551_05230	COG0477	Major facilitator Superfamily
NF551_05235	COG4770	biotin carboxylase activity
NF551_05245	COG0424	maF-like protein
NF551_05250	COG1823	symporter activity
NF551_05265	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NF551_05270	COG1028	Short-chain dehydrogenase reductase Sdr
NF551_05295	COG0714	Associated with various cellular activities
NF551_05310	COG0631	protein serine/threonine phosphatase activity
NF551_05345	COG1674	ftsk spoiiie
NF551_05420	COG4941	Belongs to the sigma-70 factor family
NF551_05430	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NF551_05450	COG0601	transmembrane transport
NF551_05455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NF551_05460	COG0444	Belongs to the ABC transporter superfamily
NF551_05465	COG1124	(ABC) transporter
NF551_05475	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NF551_05485	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NF551_05490	COG0154	amidase activity
NF551_05495	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NF551_05525	COG1254	Belongs to the acylphosphatase family
NF551_05530	COG2986	histidine ammonia-lyase
NF551_05540	COG3250	beta-galactosidase activity
NF551_05555	COG2873	o-acetylhomoserine
NF551_05560	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NF551_05580	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NF551_05600	COG2837	iron assimilation
NF551_05615	COG0423	glycine-tRNA ligase activity
NF551_05640	COG0358	DNA primase activity
NF551_05655	COG0281	malic enzyme
NF551_05660	COG0477	Major facilitator Superfamily
NF551_05670	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NF551_05680	COG0297	glycogen (starch) synthase activity
NF551_05700	COG0052	Belongs to the universal ribosomal protein uS2 family
NF551_05705	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NF551_05710	COG0528	UMP kinase activity
NF551_05715	COG0233	cytoplasmic translational termination
NF551_05720	COG0575	Belongs to the CDS family
NF551_05730	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NF551_05745	COG3275	phosphorelay sensor kinase activity
NF551_05755	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NF551_05760	COG1522	sequence-specific DNA binding
NF551_05770	COG0022	dehydrogenase e1 component
NF551_05775	COG0508	dehydrogenase complex catalyzes the overall conversion of
NF551_05785	COG1309	transcriptional regulator
NF551_05790	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NF551_05800	COG1960	acyl-CoA dehydrogenase activity
NF551_05830	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NF551_05835	COG0750	zinc metalloprotease
NF551_05855	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NF551_05870	COG0442	prolyl-tRNA aminoacylation
NF551_05890	COG0779	Required for maturation of 30S ribosomal subunits
NF551_05905	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NF551_05910	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NF551_05920	COG0436	Aminotransferase
NF551_05925	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NF551_05945	COG0196	riboflavin kinase activity
NF551_05950	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NF551_05955	COG1185	polyribonucleotide nucleotidyltransferase activity
NF551_05960	COG0612	Peptidase, M16
NF551_05975	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NF551_05990	COG0315	cyclic pyranopterin monophosphate synthase activity
NF551_05995	COG0521	Mo-molybdopterin cofactor biosynthetic process
NF551_06005	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NF551_06015	COG2814	Major facilitator Superfamily
NF551_06025	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NF551_06030	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NF551_06035	COG1674	ftsk spoiiie
NF551_06045	COG1058	Belongs to the CinA family
NF551_06045	COG1546	Belongs to the CinA family
NF551_06050	COG1396	sequence-specific DNA binding
NF551_06065	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NF551_06085	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NF551_06090	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NF551_06095	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NF551_06100	COG2813	Specifically methylates the guanine in position
NF551_06105	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NF551_06115	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NF551_06125	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NF551_06130	COG0131	Imidazoleglycerol-phosphate dehydratase
NF551_06135	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NF551_06145	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NF551_06165	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NF551_06170	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NF551_06175	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NF551_06180	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NF551_06185	COG2814	Major facilitator Superfamily
NF551_06190	COG2816	NAD+ diphosphatase activity
NF551_06215	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NF551_06220	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NF551_06220	COG0072	phenylalanine-tRNA ligase activity
NF551_06235	COG3655	Transcriptional regulator
NF551_06250	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NF551_06255	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NF551_06260	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NF551_06265	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NF551_06270	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NF551_06275	COG1438	arginine binding
NF551_06280	COG0137	argininosuccinate synthase activity
NF551_06285	COG0165	Argininosuccinate lyase
NF551_06290	COG0259	pyridoxamine-phosphate oxidase activity
NF551_06305	COG3181	Tripartite tricarboxylate transporter family receptor
NF551_06320	COG2094	Belongs to the DNA glycosylase MPG family
NF551_06325	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NF551_06335	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NF551_06365	COG0647	UMP catabolic process
NF551_06380	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NF551_06385	COG0497	DNA recombination
NF551_06390	COG0504	CTP synthase activity
NF551_06395	COG0494	nUDIX hydrolase
NF551_06405	COG1846	Transcriptional regulator
NF551_06410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NF551_06415	COG1051	belongs to the nudix hydrolase family
NF551_06435	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NF551_06440	COG2079	MmgE PrpD family protein
NF551_06455	COG4565	transcriptional regulatory protein
NF551_06460	COG3290	protein histidine kinase activity
NF551_06465	COG1301	dicarboxylic acid transport
NF551_06480	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NF551_06485	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NF551_06500	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NF551_06505	COG1160	GTP binding
NF551_06520	COG0492	ferredoxin-NADP+ reductase activity
NF551_06565	COG2133	pyrroloquinoline quinone binding
NF551_06570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NF551_06590	COG3226	Transcriptional regulator
NF551_06595	COG2132	Multicopper oxidase
NF551_06610	COG4585	Histidine kinase
NF551_06625	COG1716	ATPase activity
NF551_06665	COG1940	carbohydrate kinase activity
NF551_06680	COG0204	Acyl-transferase
NF551_06685	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
NF551_06690	COG0515	serine threonine protein kinase
NF551_06690	COG2815	serine threonine protein kinase
NF551_06695	COG1388	LysM domain
NF551_06695	COG3942	CHAP domain
NF551_06705	COG0142	geranyltranstransferase activity
NF551_06715	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NF551_06725	COG2001	Belongs to the MraZ family
NF551_06730	COG0275	rRNA processing
NF551_06740	COG0768	penicillin binding
NF551_06750	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NF551_06755	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NF551_06760	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NF551_06770	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NF551_06775	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NF551_06780	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NF551_06785	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NF551_06790	COG1496	oxidoreductase activity
NF551_06795	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NF551_06800	COG1799	cell septum assembly
NF551_06810	COG3599	regulation of cell shape
NF551_06815	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NF551_06825	COG0587	DNA-directed DNA polymerase activity
NF551_06830	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NF551_06835	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NF551_06855	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NF551_06860	COG0174	glutamine synthetase
NF551_06865	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
NF551_06870	COG0765	amino acid transport
NF551_06875	COG1126	abc transporter atp-binding protein
NF551_06880	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NF551_06900	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NF551_06905	COG0321	lipoyl(octanoyl) transferase activity
NF551_06915	COG0793	Belongs to the peptidase S41A family
NF551_06915	COG4946	Tricorn protease homolog
NF551_06925	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NF551_06930	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NF551_06940	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
NF551_06945	COG0829	nickel cation binding
NF551_06950	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NF551_06955	COG0830	nickel cation binding
NF551_06960	COG0804	urea catabolic process
NF551_06965	COG0832	Belongs to the urease beta subunit family
NF551_06975	COG0831	urea catabolic process
NF551_06980	COG1764	response to oxidative stress
NF551_06990	COG0508	dehydrogenase complex catalyzes the overall conversion of
NF551_06995	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NF551_07000	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NF551_07020	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NF551_07035	COG0501	Belongs to the peptidase M48B family
NF551_07045	COG1271	oxidase subunit
NF551_07050	COG1294	oxidase, subunit
NF551_07055	COG4988	ABC transporter
NF551_07070	COG1937	Protein conserved in bacteria
NF551_07085	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NF551_07105	COG1435	thymidine kinase activity
NF551_07125	COG0756	dUTP diphosphatase activity
NF551_07150	COG0569	domain protein
NF551_07155	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NF551_07160	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NF551_07165	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NF551_07180	COG0667	Aldo Keto reductase
NF551_07190	COG2365	Tyrosine phosphatase family
NF551_07200	COG1840	ABC-type Fe3 transport system, periplasmic component
NF551_07205	COG1178	ABC-type Fe3 transport system permease component
NF551_07210	COG3842	ATPase activity
NF551_07215	COG0406	alpha-ribazole phosphatase activity
NF551_07250	COG0745	RESPONSE REGULATOR receiver
NF551_07260	COG1929	Belongs to the glycerate kinase type-1 family
NF551_07265	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NF551_07270	COG0640	Transcriptional regulator
NF551_07275	COG0798	PFAM Bile acid sodium symporter
NF551_07280	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NF551_07300	COG1024	Enoyl-CoA hydratase
NF551_07300	COG1250	3-hydroxyacyl-CoA dehydrogenase
NF551_07305	COG0183	Belongs to the thiolase family
NF551_07320	COG1252	NADH dehydrogenase
NF551_07325	COG1595	DNA-templated transcription, initiation
NF551_07360	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NF551_07365	COG0183	Belongs to the thiolase family
NF551_07405	COG1269	ATP hydrolysis coupled proton transport
NF551_07420	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NF551_07450	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NF551_07520	COG0242	peptide deformylase activity
NF551_07525	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NF551_07535	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NF551_07545	COG0488	(ABC) transporter
NF551_07565	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NF551_07565	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NF551_07570	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NF551_07575	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NF551_07585	COG0477	Major facilitator Superfamily
NF551_07595	COG4941	Belongs to the sigma-70 factor family
NF551_07600	COG3795	YCII-related domain
NF551_07615	COG0702	epimerase
NF551_07630	COG3896	Chloramphenicol phosphotransferase-like protein
NF551_07635	COG0456	acetyltransferase
NF551_07660	COG0140	phosphoribosyl-ATP diphosphatase activity
NF551_07665	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NF551_07670	COG0107	imidazoleglycerol-phosphate synthase activity
NF551_07685	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NF551_07705	COG0134	indole-3-glycerol-phosphate synthase activity
NF551_07710	COG0133	tryptophan synthase activity
NF551_07715	COG0159	tryptophan synthase activity
NF551_07720	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NF551_07725	COG0069	glutamate synthase activity
NF551_07725	COG0067	glutamate synthase
NF551_07725	COG0070	glutamate synthase
NF551_07735	COG0469	pyruvate kinase activity
NF551_07755	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NF551_07780	COG1940	carbohydrate kinase activity
NF551_07790	COG0471	metal ion transport
NF551_07800	COG0415	Belongs to the DNA photolyase family
NF551_07815	COG1132	(ABC) transporter
NF551_07820	COG0454	-acetyltransferase
NF551_07840	COG2890	protein-(glutamine-N5) methyltransferase activity
NF551_07845	COG3585	molybdate ion transport
NF551_07870	COG5000	phosphorelay sensor kinase activity
NF551_07870	COG5002	protein histidine kinase activity
NF551_07880	COG3173	Aminoglycoside phosphotransferase
NF551_07890	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NF551_07900	COG1643	Atp-dependent helicase
NF551_07905	COG1329	Transcriptional regulator
NF551_07910	COG3103	Sh3 type 3 domain protein
NF551_07910	COG1388	LysM domain
NF551_07910	COG0791	NLP P60 protein
NF551_07915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NF551_07935	COG1120	ATPase activity
NF551_07940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NF551_07955	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NF551_07960	COG0569	domain protein
NF551_07965	COG1937	Protein conserved in bacteria
NF551_07975	COG1785	Belongs to the alkaline phosphatase family
NF551_07980	COG0009	L-threonylcarbamoyladenylate synthase
NF551_08000	COG1793	dna ligase
NF551_08000	COG3285	dna ligase
NF551_08005	COG0778	Nitroreductase
NF551_08010	COG1215	transferase activity, transferring glycosyl groups
NF551_08035	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NF551_08045	COG2272	Belongs to the type-B carboxylesterase lipase family
NF551_08050	COG0488	(ABC) transporter
NF551_08060	COG2272	Belongs to the type-B carboxylesterase lipase family
NF551_08075	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NF551_08080	COG1793	dna ligase
NF551_08085	COG1607	acyl-coa hydrolase
NF551_08090	COG2807	transmembrane transport
NF551_08095	COG1472	Belongs to the glycosyl hydrolase 3 family
NF551_08100	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NF551_08105	COG0477	Major facilitator Superfamily
NF551_08110	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NF551_08115	COG1082	Xylose isomerase domain protein TIM barrel
NF551_08115	COG3185	4-Hydroxyphenylpyruvate dioxygenase
NF551_08120	COG1414	Transcriptional regulator
NF551_08130	COG0531	amino acid
NF551_08135	COG0076	glutamate decarboxylase activity
NF551_08150	COG2050	protein possibly involved in aromatic compounds catabolism
NF551_08165	COG0539	negative regulation of cytoplasmic translation
NF551_08180	COG2723	6-phospho-beta-galactosidase activity
NF551_08205	COG1739	Uncharacterized protein family UPF0029
NF551_08210	COG0237	dephospho-CoA kinase activity
NF551_08210	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NF551_08215	COG0556	nucleotide-excision repair
NF551_08250	COG4106	trans-aconitate 2-methyltransferase activity
NF551_08290	COG0322	excinuclease ABC activity
NF551_08295	COG1660	Displays ATPase and GTPase activities
NF551_08305	COG1481	regulation of sporulation
NF551_08320	COG0126	phosphoglycerate kinase activity
NF551_08325	COG0149	triose-phosphate isomerase activity
NF551_08330	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NF551_08335	COG0363	glucosamine-6-phosphate deaminase activity
NF551_08350	COG0166	Belongs to the GPI family
NF551_08355	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NF551_08365	COG0109	protoheme IX farnesyltransferase activity
NF551_08370	COG1612	heme a metabolic process
NF551_08380	COG1131	(ABC) transporter
NF551_08400	COG0396	ATPase activity
NF551_08405	COG2151	metal-sulfur cluster biosynthetic enzyme
NF551_08415	COG1122	ATPase activity
NF551_08420	COG1268	BioY protein
NF551_08425	COG0488	(ABC) transporter
NF551_08450	COG1028	Short-chain dehydrogenase reductase Sdr
NF551_08455	COG3830	Belongs to the UPF0237 family
NF551_08455	COG0560	Phosphoserine phosphatase
NF551_08460	COG1119	ATPase activity
NF551_08480	COG0254	rRNA binding
NF551_08505	COG2855	membrane
NF551_08510	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NF551_08525	COG0297	glycogen (starch) synthase activity
NF551_08545	COG1028	Short-chain dehydrogenase reductase Sdr
NF551_08560	COG0589	response to stress
NF551_08570	COG1253	flavin adenine dinucleotide binding
NF551_08580	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NF551_08600	COG1968	undecaprenyl-diphosphatase activity
NF551_08605	COG0215	cysteine-tRNA ligase activity
NF551_08615	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NF551_08630	COG1222	aaa ATPase
NF551_08635	COG4122	O-methyltransferase activity
NF551_08645	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NF551_08650	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NF551_08655	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NF551_08680	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NF551_08685	COG0805	protein transport
NF551_08690	COG4581	dead DEAH box helicase
NF551_08700	COG1216	Glycosyl transferase, family 2
NF551_08725	COG0823	Involved in the tonB-independent uptake of proteins
NF551_08725	COG1506	peptidase
NF551_08725	COG4946	Tricorn protease homolog
NF551_08730	COG0242	peptide deformylase activity
NF551_08775	COG1028	Short-chain dehydrogenase reductase Sdr
NF551_08805	COG1136	(ABC) transporter
NF551_08825	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NF551_08830	COG1845	cytochrome c oxidase, subunit III
NF551_08835	COG2010	Cytochrome c
NF551_08840	COG0723	plastoquinol--plastocyanin reductase activity
NF551_08845	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NF551_08855	COG2188	Transcriptional regulator
NF551_08865	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NF551_08870	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NF551_08890	COG0167	dihydroorotate dehydrogenase activity
NF551_08900	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NF551_08905	COG1381	Involved in DNA repair and RecF pathway recombination
NF551_08910	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NF551_08915	COG1316	TRANSCRIPTIONal
NF551_08920	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NF551_08930	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NF551_08950	COG0484	heat shock protein binding
NF551_08955	COG1420	regulation of RNA biosynthetic process
NF551_08975	COG0481	GTPase activity
NF551_08985	COG0268	Binds directly to 16S ribosomal RNA
NF551_09030	COG1307	EDD domain protein, DegV family
NF551_09035	COG0495	leucyl-tRNA aminoacylation
NF551_09045	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NF551_09050	COG0385	Bile acid
NF551_09055	COG2072	flavoprotein involved in K transport
NF551_09060	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NF551_09065	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NF551_09070	COG0656	L-ascorbic acid biosynthetic process
NF551_09075	COG0596	Alpha beta hydrolase
NF551_09080	COG0438	transferase activity, transferring glycosyl groups
NF551_09085	COG2130	NADP-dependent
NF551_09100	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NF551_09110	COG1758	RNA polymerase activity
NF551_09115	COG0194	GDP metabolic process
NF551_09120	COG0194	GDP metabolic process
NF551_09125	COG0284	orotidine-5'-phosphate decarboxylase activity
NF551_09130	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NF551_09135	COG0505	Belongs to the CarA family
NF551_09145	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NF551_09150	COG0540	Belongs to the ATCase OTCase family
NF551_09155	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NF551_09165	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NF551_09170	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NF551_09175	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NF551_09180	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NF551_09185	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NF551_09190	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NF551_09205	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NF551_09220	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NF551_09230	COG0384	phenazine biosynthesis protein PhzF
NF551_09255	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NF551_09270	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NF551_09275	COG2070	2-Nitropropane dioxygenase
NF551_09290	COG1968	undecaprenyl-diphosphatase activity
NF551_09315	COG0596	Alpha beta hydrolase
NF551_09320	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NF551_09325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NF551_09330	COG1116	anion transmembrane transporter activity
NF551_09335	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NF551_09345	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NF551_09360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NF551_09365	COG1120	ATPase activity
NF551_09370	COG0778	Nitroreductase
NF551_09370	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
NF551_09375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NF551_09380	COG0124	histidyl-tRNA synthetase
NF551_09390	COG1196	nuclear chromosome segregation
NF551_09400	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NF551_09405	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NF551_09410	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NF551_09425	COG0632	four-way junction helicase activity
NF551_09430	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NF551_09435	COG0217	transcriptional regulatory protein
NF551_09440	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NF551_09445	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NF551_09470	COG0339	signal peptide processing
NF551_09480	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NF551_09485	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NF551_09495	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NF551_09500	COG0587	DNA-directed DNA polymerase activity
NF551_09530	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NF551_09540	COG2409	Drug exporters of the RND superfamily
NF551_09550	COG2135	peptidase activity
NF551_09565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NF551_09605	COG0667	Aldo Keto reductase
NF551_09610	COG2135	peptidase activity
NF551_09620	COG0346	lactoylglutathione lyase activity
NF551_09635	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NF551_09640	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NF551_09670	COG0667	Aldo Keto reductase
NF551_09675	COG0442	prolyl-tRNA aminoacylation
NF551_09700	COG1231	oxidoreductase activity
NF551_09715	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NF551_09720	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NF551_09725	COG1780	Probably involved in ribonucleotide reductase function
NF551_09730	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NF551_09735	COG0583	DNA-binding transcription factor activity
NF551_09760	COG3621	Patatin-like phospholipase
NF551_09765	COG0789	Transcriptional regulator
NF551_09795	COG4989	oxidoreductase activity
NF551_09820	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NF551_09830	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NF551_09835	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NF551_09840	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NF551_09845	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NF551_09850	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NF551_09855	COG1530	ribonuclease E activity
NF551_09870	COG0105	UTP biosynthetic process
NF551_09880	COG0285	dihydrofolate synthase activity
NF551_09885	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NF551_09890	COG4221	oxidoreductase activity
NF551_09900	COG3189	MarR family transcriptional regulator
NF551_09905	COG0525	valine-tRNA ligase activity
NF551_09910	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NF551_09915	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NF551_09920	COG0740	serine-type endopeptidase activity
NF551_09925	COG0740	serine-type endopeptidase activity
NF551_09930	COG0544	peptidyl-prolyl cis-trans isomerase activity
NF551_09955	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
NF551_09955	COG5479	isomerase activity
NF551_09970	COG0668	transmembrane transport
NF551_09985	COG0824	Thioesterase
NF551_09990	COG1946	Acyl-CoA thioesterase
NF551_10005	COG0629	single-stranded DNA binding
NF551_10075	COG0242	peptide deformylase activity
NF551_10095	COG3022	response to hydroperoxide
NF551_10110	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NF551_10115	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NF551_10130	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NF551_10165	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
NF551_10190	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NF551_10195	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NF551_10200	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NF551_10210	COG4974	Belongs to the 'phage' integrase family
NF551_10230	COG0792	nuclease activity
NF551_10250	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NF551_10255	COG0681	Belongs to the peptidase S26 family
NF551_10260	COG0681	Belongs to the peptidase S26 family
NF551_10265	COG0335	large ribosomal subunit rRNA binding
NF551_10270	COG0336	Belongs to the RNA methyltransferase TrmD family
NF551_10275	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NF551_10280	COG1837	Belongs to the UPF0109 family
NF551_10285	COG0228	four-way junction DNA binding
NF551_10290	COG2514	catechol 2,3-dioxygenase activity
NF551_10315	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NF551_10340	COG0477	Major facilitator Superfamily
NF551_10355	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NF551_10360	COG0318	PFAM AMP-dependent synthetase and ligase
NF551_10365	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NF551_10375	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NF551_10380	COG0571	ribonuclease III activity
NF551_10385	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NF551_10400	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NF551_10415	COG0742	ribosomal rna small subunit methyltransferase
NF551_10425	COG1461	Dihydroxyacetone kinase
NF551_10435	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NF551_10450	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NF551_10460	COG1134	teichoic acid transport
NF551_10465	COG1682	transport, permease protein
NF551_10470	COG0438	transferase activity, transferring glycosyl groups
NF551_10495	COG1181	Belongs to the D-alanine--D-alanine ligase family
NF551_10500	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NF551_10510	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NF551_10515	COG0066	3-isopropylmalate dehydratase activity
NF551_10520	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NF551_10525	COG1414	Transcriptional regulator
NF551_10530	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NF551_10560	COG0546	phosphoglycolate phosphatase activity
NF551_10565	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NF551_10575	COG0179	Fumarylacetoacetate (FAA) hydrolase
NF551_10600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NF551_10605	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NF551_10610	COG0473	3-isopropylmalate dehydrogenase activity
NF551_10615	COG4585	Histidine kinase
NF551_10620	COG2197	response regulator
NF551_10630	COG1136	(ABC) transporter
NF551_10630	COG0577	efflux transmembrane transporter activity
NF551_10635	COG1136	(ABC) transporter
NF551_10635	COG0577	efflux transmembrane transporter activity
NF551_10655	COG0577	efflux transmembrane transporter activity
NF551_10655	COG1136	(ABC) transporter
NF551_10660	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NF551_10665	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NF551_10670	COG0440	acetolactate synthase activity
NF551_10680	COG0129	dihydroxy-acid dehydratase activity
NF551_10720	COG0183	Belongs to the thiolase family
NF551_10725	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NF551_10730	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NF551_10755	COG1960	acyl-CoA dehydrogenase activity
NF551_10800	COG1172	Belongs to the binding-protein-dependent transport system permease family
NF551_10820	COG0747	negative chemotaxis
NF551_10825	COG0601	transmembrane transport
NF551_10830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NF551_10840	COG0747	negative chemotaxis
NF551_10845	COG0579	oxidoreductase
NF551_10850	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NF551_10855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NF551_10865	COG2814	Major facilitator Superfamily
NF551_10870	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NF551_10875	COG1104	cysteine desulfurase activity
NF551_10885	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NF551_10905	COG0022	dehydrogenase e1 component
NF551_10910	COG0508	dehydrogenase complex catalyzes the overall conversion of
NF551_10920	COG0515	serine threonine protein kinase
NF551_10920	COG2815	serine threonine protein kinase
NF551_10930	COG1116	anion transmembrane transporter activity
NF551_10935	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NF551_10945	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NF551_10955	COG0419	ATPase involved in DNA repair
NF551_10960	COG0420	3'-5' exonuclease activity
NF551_10965	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NF551_10980	COG0586	Pfam SNARE associated Golgi protein
NF551_10985	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NF551_10990	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NF551_11000	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NF551_11010	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NF551_11020	COG1335	isochorismatase
NF551_11075	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
NF551_11085	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NF551_11095	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NF551_11100	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NF551_11105	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NF551_11110	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NF551_11115	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NF551_11120	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NF551_11125	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NF551_11130	COG0356	it plays a direct role in the translocation of protons across the membrane
NF551_11160	COG1216	Glycosyl transferase, family 2
NF551_11165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NF551_11175	COG2890	protein-(glutamine-N5) methyltransferase activity
NF551_11180	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NF551_11190	COG0083	homoserine kinase activity
NF551_11195	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NF551_11200	COG0460	homoserine dehydrogenase
NF551_11205	COG0019	diaminopimelate decarboxylase activity
NF551_11210	COG0018	arginyl-trna synthetase
NF551_11235	COG0577	efflux transmembrane transporter activity
NF551_11240	COG0577	efflux transmembrane transporter activity
NF551_11240	COG1136	(ABC) transporter
NF551_11270	COG1643	Atp-dependent helicase
NF551_11275	COG0537	adenosine 5'-monophosphoramidase activity
NF551_11295	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NF551_11300	COG1121	(ABC) transporter
NF551_11315	COG1253	flavin adenine dinucleotide binding
NF551_11320	COG0508	dehydrogenase complex catalyzes the overall conversion of
NF551_11320	COG0567	Dehydrogenase, E1 component
NF551_11330	COG0604	alcohol dehydrogenase
NF551_11340	COG1595	DNA-templated transcription, initiation
NF551_11350	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NF551_11360	COG0483	inositol monophosphate 1-phosphatase activity
NF551_11370	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NF551_11375	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NF551_11380	COG0366	Alpha amylase catalytic
NF551_11445	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
NF551_11455	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
NF551_11475	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NF551_11480	COG0739	heme binding
NF551_11485	COG2177	Part of the ABC transporter FtsEX involved in
NF551_11490	COG2884	Cell division ATP-binding protein ftsE
NF551_11500	COG1028	Short-chain dehydrogenase reductase Sdr
NF551_11510	COG0318	PFAM AMP-dependent synthetase and ligase
NF551_11540	COG2755	lipolytic protein G-D-S-L family
NF551_11540	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NF551_11545	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NF551_11600	COG1088	dTDP-glucose 4,6-dehydratase activity
NF551_11610	COG1215	transferase activity, transferring glycosyl groups
NF551_11615	COG0463	Glycosyl transferase, family 2
NF551_11645	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NF551_11665	COG1216	Glycosyl transferase, family 2
NF551_11675	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NF551_11675	COG2755	lipolytic protein G-D-S-L family
NF551_11695	COG2902	Dehydrogenase
NF551_11730	COG0653	protein targeting
NF551_11735	COG3214	Protein conserved in bacteria
NF551_11740	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NF551_11750	COG5401	PFAM Sporulation and spore germination
NF551_11755	COG5002	protein histidine kinase activity
NF551_11760	COG0745	RESPONSE REGULATOR receiver
NF551_11780	COG0714	Associated with various cellular activities
NF551_11805	COG0482	sulfurtransferase activity
NF551_11815	COG0484	heat shock protein binding
NF551_11820	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NF551_11825	COG2226	methyltransferase
NF551_11830	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NF551_11835	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
NF551_11840	COG2086	electron transfer activity
NF551_11845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NF551_11855	COG1842	Phage shock protein A
NF551_11870	COG1615	UPF0182 protein
NF551_11875	COG3480	Lon protease (S16) C-terminal proteolytic domain
NF551_11915	COG1131	(ABC) transporter
NF551_11925	COG0210	DNA helicase
NF551_11945	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NF551_11960	COG1131	(ABC) transporter
NF551_11970	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NF551_11975	COG0113	porphobilinogen synthase activity
NF551_11985	COG0181	hydroxymethylbilane synthase activity
NF551_11990	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NF551_11995	COG3253	May function as heme-dependent peroxidase
NF551_12000	COG1231	oxidoreductase activity
NF551_12005	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NF551_12010	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NF551_12045	COG0513	Belongs to the DEAD box helicase family
NF551_12055	COG0613	PHP domain protein
NF551_12060	COG0006	proline dipeptidase activity
NF551_12070	COG2239	Acts as a magnesium transporter
NF551_12085	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NF551_12095	COG1595	DNA-templated transcription, initiation
NF551_12100	COG4122	O-methyltransferase activity
NF551_12105	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NF551_12115	COG0519	Catalyzes the synthesis of GMP from XMP
NF551_12125	COG1611	Belongs to the LOG family
NF551_12130	COG1126	abc transporter atp-binding protein
NF551_12135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NF551_12140	COG0765	amino acid transport
NF551_12145	COG0765	amino acid transport
NF551_12150	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NF551_12155	COG2171	N-acyltransferase activity
NF551_12165	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NF551_12200	COG1217	gtp-binding protein TYPA
NF551_12210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NF551_12215	COG0601	transmembrane transport
NF551_12220	COG4166	transmembrane transport
NF551_12235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NF551_12245	COG4166	transmembrane transport
NF551_12300	COG0012	GTP binding
NF551_12305	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NF551_12315	COG1570	exodeoxyribonuclease VII activity
NF551_12320	COG1722	exodeoxyribonuclease VII activity
NF551_12350	COG1051	belongs to the nudix hydrolase family
NF551_12355	COG2971	BadF BadG BcrA BcrD
NF551_12375	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NF551_12380	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NF551_12405	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NF551_12405	COG0519	Catalyzes the synthesis of GMP from XMP
NF551_12425	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NF551_12430	COG0516	GMP reductase activity
NF551_12440	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NF551_12440	COG2755	lipolytic protein G-D-S-L family
NF551_12445	COG0459	protein refolding
NF551_12450	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NF551_12455	COG4607	ABC-type enterochelin transport system periplasmic component
NF551_12460	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NF551_12465	COG4605	iron ion homeostasis
NF551_12470	COG4604	ABC transporter, ATP-binding protein
NF551_12490	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NF551_12505	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NF551_12510	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NF551_12520	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NF551_12530	COG0456	acetyltransferase
NF551_12530	COG1214	PFAM Peptidase M22, glycoprotease
NF551_12545	COG0802	atpase or kinase
NF551_12550	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NF551_12560	COG0667	Aldo Keto reductase
NF551_12585	COG0736	holo-[acyl-carrier-protein] synthase activity
NF551_12595	COG1072	(Pantothenic acid kinase))
NF551_12600	COG1970	mechanosensitive ion channel activity
NF551_12605	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NF551_12610	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NF551_12615	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NF551_12620	COG0101	tRNA pseudouridine synthase activity
NF551_12625	COG0203	ribosomal protein L17
NF551_12630	COG0202	RNA polymerase activity
NF551_12635	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NF551_12640	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NF551_12645	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NF551_12650	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NF551_12665	COG0024	Methionine aminopeptidase
NF551_12670	COG0563	adenylate kinase activity
NF551_12680	COG0200	Binds to the 23S rRNA
NF551_12685	COG1841	ribosomal large subunit assembly
NF551_12690	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NF551_12700	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NF551_12705	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NF551_12710	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NF551_12715	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NF551_12720	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NF551_12725	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NF551_12735	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NF551_12740	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NF551_12745	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NF551_12750	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NF551_12755	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NF551_12760	COG0089	rRNA binding
NF551_12765	COG0088	Forms part of the polypeptide exit tunnel
NF551_12770	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NF551_12775	COG0051	transcription antitermination factor activity, RNA binding
NF551_12790	COG0318	PFAM AMP-dependent synthetase and ligase
NF551_12795	COG1960	acyl-CoA dehydrogenase activity
NF551_12800	COG0446	pyridine nucleotide-disulphide oxidoreductase
NF551_12800	COG1902	pentaerythritol trinitrate reductase activity
NF551_12805	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NF551_12810	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NF551_12815	COG0049	tRNA binding
NF551_12820	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NF551_12825	COG1414	Transcriptional regulator
NF551_12830	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NF551_12840	COG0183	Belongs to the thiolase family
NF551_12845	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NF551_12860	COG3485	protocatechuate 3,4-dioxygenase
NF551_12865	COG3485	protocatechuate 3,4-dioxygenase
NF551_12880	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NF551_12885	COG0085	RNA polymerase activity
NF551_12890	COG0183	Belongs to the thiolase family
NF551_12895	COG0442	prolyl-tRNA aminoacylation
NF551_12900	COG0222	ribosome binding
NF551_12905	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NF551_12915	COG0081	regulation of translation
NF551_12920	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NF551_12940	COG0436	Aminotransferase
NF551_12945	COG2197	response regulator
NF551_12985	COG0354	folic acid binding
NF551_12990	COG3485	protocatechuate 3,4-dioxygenase
NF551_13000	COG0745	RESPONSE REGULATOR receiver
NF551_13005	COG0456	acetyltransferase
NF551_13010	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NF551_13030	COG1725	Transcriptional regulator
NF551_13035	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NF551_13040	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NF551_13045	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NF551_13050	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NF551_13060	COG2030	dehydratase
NF551_13075	COG0693	protein deglycase activity
NF551_13095	COG0515	serine threonine protein kinase
NF551_13150	COG1063	alcohol dehydrogenase
NF551_13155	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NF551_13175	COG1666	GTP binding
NF551_13185	COG0501	Belongs to the peptidase M48B family
NF551_13195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NF551_13245	COG0142	geranyltranstransferase activity
NF551_13250	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
NF551_13265	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NF551_13320	COG0477	Major facilitator Superfamily
NF551_13385	COG0142	geranyltranstransferase activity
NF551_13395	COG2226	methyltransferase
NF551_13405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NF551_13415	COG0765	amino acid transport
NF551_13420	COG1126	abc transporter atp-binding protein
NF551_13425	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NF551_13435	COG4948	Mandelate Racemase Muconate Lactonizing
NF551_13455	COG0508	dehydrogenase complex catalyzes the overall conversion of
NF551_13460	COG0022	dehydrogenase e1 component
NF551_13480	COG2837	iron assimilation
NF551_13500	COG1024	Enoyl-CoA hydratase
NF551_13505	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NF551_13510	COG2151	metal-sulfur cluster biosynthetic enzyme
NF551_13515	COG3396	Phenylacetate-CoA oxygenase
NF551_13520	COG3460	Phenylacetate-CoA oxygenase
NF551_13525	COG3396	Phenylacetate-CoA oxygenase
NF551_13545	COG0586	Pfam SNARE associated Golgi protein
NF551_13565	COG2030	dehydratase
NF551_13565	COG1012	belongs to the aldehyde dehydrogenase family
NF551_13585	COG1250	3-hydroxyacyl-CoA dehydrogenase
NF551_13590	COG1024	Enoyl-CoA hydratase
NF551_13635	COG0604	alcohol dehydrogenase
NF551_13635	COG1028	Short-chain dehydrogenase reductase Sdr
NF551_13635	COG3321	synthase
NF551_13640	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NF551_13665	COG1140	nitrate reductase beta subunit
NF551_13675	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NF551_13710	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NF551_13720	COG0785	Cytochrome C biogenesis protein
NF551_13725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NF551_13730	COG0406	alpha-ribazole phosphatase activity
NF551_13735	COG2353	YceI-like domain
NF551_13750	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NF551_13775	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NF551_13785	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NF551_13790	COG0640	Transcriptional regulator
NF551_13795	COG0123	including yeast histone deacetylase and acetoin utilization protein
NF551_13800	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NF551_13805	COG0569	domain protein
NF551_13815	COG1082	Xylose isomerase domain protein TIM barrel
NF551_13820	COG0248	Ppx GppA phosphatase
NF551_13825	COG1754	DNA topoisomerase type I activity
NF551_13825	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NF551_13830	COG2890	protein-(glutamine-N5) methyltransferase activity
NF551_13835	COG2814	Major facilitator Superfamily
NF551_13845	COG1053	succinate dehydrogenase
NF551_13850	COG1054	Belongs to the UPF0176 family
NF551_13860	COG1111	helicase
NF551_13860	COG1205	dead DEAH box helicase
NF551_13910	COG4585	Histidine kinase
NF551_13915	COG2197	response regulator
NF551_13925	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NF551_13935	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NF551_13940	COG1764	response to oxidative stress
NF551_13950	COG0477	Major facilitator Superfamily
NF551_13985	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NF551_13990	COG1408	metallophosphoesterase
NF551_13995	COG1132	(ABC) transporter
NF551_14000	COG1132	(ABC) transporter
NF551_14015	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NF551_14020	COG0151	Belongs to the GarS family
NF551_14045	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NF551_14070	COG0768	penicillin binding
NF551_14080	COG3304	Inner membrane component domain
NF551_14105	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NF551_14125	COG1131	(ABC) transporter
NF551_14140	COG0484	heat shock protein binding
NF551_14145	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NF551_14150	COG0443	Heat shock 70 kDa protein
NF551_14155	COG2226	methyltransferase
NF551_14160	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NF551_14170	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NF551_14185	COG1122	ATPase activity
NF551_14205	COG2212	antiporter activity
NF551_14215	COG0651	ATP synthesis coupled electron transport
NF551_14225	COG2111	Na H antiporter
NF551_14225	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NF551_14240	COG1028	Short-chain dehydrogenase reductase Sdr
NF551_14245	COG1053	succinate dehydrogenase
NF551_14260	COG1053	succinate dehydrogenase
NF551_14275	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NF551_14280	COG0477	Major facilitator Superfamily
NF551_14285	COG0583	DNA-binding transcription factor activity
NF551_14290	COG1053	succinate dehydrogenase
NF551_14295	COG0717	Belongs to the dCTP deaminase family
NF551_14300	COG3483	tryptophan 2,3-dioxygenase activity
NF551_14325	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NF551_14365	COG0776	regulation of translation
NF551_14370	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NF551_14375	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NF551_14380	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NF551_14385	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NF551_14395	COG0477	Major facilitator Superfamily
NF551_14405	COG1597	lipid kinase activity
NF551_14410	COG0739	heme binding
NF551_14420	COG1120	ATPase activity
NF551_14425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NF551_14430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NF551_14435	COG0435	Glutathione S-transferase
NF551_14445	COG1295	ribonuclease BN
NF551_14465	COG0446	pyridine nucleotide-disulphide oxidoreductase
NF551_14510	COG1028	Short-chain dehydrogenase reductase Sdr
NF551_14515	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
NF551_14530	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NF551_14550	COG0531	amino acid
NF551_14560	COG0477	Major facilitator Superfamily
NF551_14570	COG1473	amidohydrolase
NF551_14575	COG4585	Histidine kinase
NF551_14580	COG2197	response regulator
NF551_14585	COG4152	abc transporter atp-binding protein
NF551_14600	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
NF551_14605	COG1414	Transcriptional regulator
NF551_14620	COG3257	ureidoglycine aminohydrolase activity
NF551_14625	COG3622	Belongs to the hyi family
NF551_14630	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NF551_14695	COG1028	Short-chain dehydrogenase reductase Sdr
NF551_14710	COG1012	belongs to the aldehyde dehydrogenase family
NF551_14725	COG0318	PFAM AMP-dependent synthetase and ligase
NF551_14735	COG1028	Short-chain dehydrogenase reductase Sdr
NF551_14760	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NF551_14765	COG1984	allophanate hydrolase subunit 2
NF551_14770	COG0028	Belongs to the TPP enzyme family
NF551_14785	COG1129	ABC transporter
NF551_14800	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NF551_14820	COG0596	Alpha beta hydrolase
NF551_14825	COG5002	protein histidine kinase activity
NF551_14845	COG1072	(Pantothenic acid kinase))
NF551_14865	COG0366	Alpha amylase catalytic
NF551_14875	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NF551_14880	COG3639	organic phosphonate transmembrane transporter activity
NF551_14935	COG4592	Periplasmic binding protein
NF551_14940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NF551_14945	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NF551_14950	COG1120	ATPase activity
NF551_14960	COG2382	esterase
NF551_14970	COG1846	Transcriptional regulator
NF551_14980	COG2807	transmembrane transport
NF551_15015	COG1522	sequence-specific DNA binding
NF551_15030	COG0546	phosphoglycolate phosphatase activity
NF551_15045	COG2124	cytochrome p450
NF551_15055	COG1414	Transcriptional regulator
NF551_15065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NF551_15080	COG2072	flavoprotein involved in K transport
NF551_15090	COG0277	FAD linked oxidase domain protein
NF551_15100	COG2329	Antibiotic biosynthesis monooxygenase
NF551_15105	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NF551_15110	COG2076	Multidrug Resistance protein
NF551_15115	COG2076	Multidrug Resistance protein
NF551_15130	COG0531	amino acid
NF551_15180	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NF551_15225	COG1121	(ABC) transporter
NF551_15230	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NF551_15240	COG2217	Heavy metal translocating P-type atpase
NF551_15265	COG0656	L-ascorbic acid biosynthetic process
NF551_15290	COG1120	ATPase activity
NF551_15305	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NF551_15315	COG1028	Short-chain dehydrogenase reductase Sdr
NF551_15320	COG1053	succinate dehydrogenase
NF551_15325	COG0477	Major facilitator Superfamily
NF551_15335	COG1053	succinate dehydrogenase
NF551_15340	COG1414	Transcriptional regulator
NF551_15355	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
NF551_15360	COG2116	formate transmembrane transporter activity
NF551_15400	COG1120	ATPase activity
NF551_15430	COG1012	belongs to the aldehyde dehydrogenase family
NF551_15465	COG1178	ABC-type Fe3 transport system permease component
NF551_15470	COG3842	ATPase activity
NF551_15485	COG1028	Short-chain dehydrogenase reductase Sdr
NF551_15495	COG1653	transport
NF551_15510	COG0673	inositol 2-dehydrogenase activity
NF551_15525	COG0673	inositol 2-dehydrogenase activity
NF551_15530	COG1879	ABC-type sugar transport system periplasmic component
NF551_15535	COG1129	ABC transporter
NF551_15540	COG1172	Belongs to the binding-protein-dependent transport system permease family
NF551_15550	COG1940	carbohydrate kinase activity
NF551_15570	COG0084	hydrolase, TatD family'
NF551_15580	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NF551_15610	COG0598	Magnesium transport protein CorA
NF551_15650	COG1028	Short-chain dehydrogenase reductase Sdr
NF551_15660	COG0477	Major facilitator Superfamily
NF551_15685	COG2233	PERMEase
NF551_15710	COG3608	succinylglutamate desuccinylase aspartoacylase
NF551_15710	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NF551_15720	COG2080	2 iron, 2 sulfur cluster binding
NF551_15720	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NF551_15730	COG2409	Drug exporters of the RND superfamily
NF551_15740	COG0277	FAD linked oxidase domain protein
NF551_15745	COG1620	l-lactate permease
NF551_15750	COG1028	Short-chain dehydrogenase reductase Sdr
NF551_15755	COG1115	amino acid carrier protein
NF551_15775	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NF551_15780	COG0509	glycine decarboxylation via glycine cleavage system
NF551_15785	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NF551_15790	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NF551_15790	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NF551_15795	COG1113	amino acid transport
NF551_15800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NF551_15825	COG1302	Protein conserved in bacteria
NF551_15830	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NF551_15845	COG0686	Belongs to the AlaDH PNT family
NF551_15855	COG0673	inositol 2-dehydrogenase activity
NF551_15890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NF551_15900	COG0508	dehydrogenase complex catalyzes the overall conversion of
NF551_15905	COG0022	dehydrogenase e1 component
NF551_15915	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NF551_15920	COG1950	PFAM Membrane protein of
NF551_15935	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NF551_15945	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NF551_15975	COG0590	tRNA wobble adenosine to inosine editing
NF551_15985	COG2807	transmembrane transport
NF551_15995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NF551_16025	COG2124	cytochrome p450
NF551_16040	COG1309	transcriptional regulator
NF551_16060	COG1063	alcohol dehydrogenase
NF551_16065	COG0395	ABC-type sugar transport system, permease component
NF551_16070	COG1175	transmembrane transport
NF551_16120	COG3145	DNA-N1-methyladenine dioxygenase activity
NF551_16125	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NF551_16130	COG1595	DNA-templated transcription, initiation
NF551_16135	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NF551_16150	COG1960	acyl-CoA dehydrogenase activity
NF551_16160	COG1028	Short-chain dehydrogenase reductase Sdr
NF551_16165	COG0659	secondary active sulfate transmembrane transporter activity
NF551_16175	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NF551_16180	COG1546	Belongs to the CinA family
NF551_16180	COG1058	Belongs to the CinA family
NF551_16210	COG3546	catalase activity
NF551_16220	COG0318	PFAM AMP-dependent synthetase and ligase
NF551_16260	COG2814	Major facilitator Superfamily
NF551_16275	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NF551_16280	COG1652	LysM domain
NF551_16285	COG0531	amino acid
NF551_16295	COG0305	Participates in initiation and elongation during chromosome replication
NF551_16300	COG0359	binds to the 23S rRNA
NF551_16305	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NF551_16315	COG0360	Binds together with S18 to 16S ribosomal RNA
NF551_16320	COG1362	aminopeptidase activity
NF551_16330	COG1131	(ABC) transporter
NF551_16355	COG0738	Major facilitator superfamily
NF551_16360	COG0488	(ABC) transporter
NF551_16405	COG2759	Belongs to the formate--tetrahydrofolate ligase family
NF551_16410	COG0438	transferase activity, transferring glycosyl groups
NF551_16415	COG0406	alpha-ribazole phosphatase activity
NF551_16420	COG0617	tRNA 3'-terminal CCA addition
NF551_16440	COG0492	ferredoxin-NADP+ reductase activity
NF551_16445	COG3118	belongs to the thioredoxin family
NF551_16450	COG3409	Peptidoglycan-binding domain 1 protein
NF551_16450	COG0860	N-Acetylmuramoyl-L-alanine amidase
NF551_16470	COG1475	DNA binding
NF551_16475	COG1192	Involved in chromosome partitioning
NF551_16480	COG0357	Ribosomal RNA small subunit methyltransferase G
NF551_16490	COG0706	membrane insertase activity
NF551_16495	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NF551_16500	COG0594	ribonuclease P activity
NF551_16505	COG0230	Belongs to the bacterial ribosomal protein bL34 family
NF551_16740	COG3550	peptidyl-serine autophosphorylation
NF551_16775	COG3177	Filamentation induced by cAMP protein fic
NF551_16815	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
NF551_16815	COG5479	isomerase activity
NF551_16870	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NF551_17000	COG0328	RNA-DNA hybrid ribonuclease activity
NF551_17045	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NF551_17120	COG1842	Phage shock protein A
NF551_17160	COG0741	lytic transglycosylase activity
NF551_17200	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NF551_17200	COG2755	lipolytic protein G-D-S-L family
NF551_17220	COG0617	tRNA 3'-terminal CCA addition
NF551_17270	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NF551_17295	COG4152	abc transporter atp-binding protein
NF551_17300	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NF551_17315	COG0492	ferredoxin-NADP+ reductase activity
NF551_17395	COG0756	dUTP diphosphatase activity
NF551_17655	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NF551_17685	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NF551_17705	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NF551_17750	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NF551_17755	COG0025	NhaP-type Na H and K H
NF551_17865	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NF551_17945	COG0754	glutathionylspermidine amidase activity
NF551_17995	COG1690	Belongs to the RtcB family
NF551_18080	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NF551_18090	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NF551_18105	COG2176	DNA-directed DNA polymerase activity
NF551_18200	COG2268	Band 7 protein
NF551_18220	COG0741	lytic transglycosylase activity
NF551_18220	COG0739	heme binding
NF551_18220	COG1196	nuclear chromosome segregation
NF551_18320	COG2894	cell division
NF551_18360	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NF551_18535	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NF551_18680	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NF551_18895	COG1674	ftsk spoiiie