locus-tag	class	description
MUK71_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MUK71_00010	COG0592	DNA-directed DNA polymerase activity
MUK71_00015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
MUK71_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MUK71_00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
MUK71_00030	COG0187	DNA topoisomerase II activity
MUK71_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MUK71_00040	COG3266	domain, Protein
MUK71_00075	COG0705	Rhomboid family
MUK71_00085	COG3764	Sortase (surface protein transpeptidase)
MUK71_00100	COG2815	serine threonine protein kinase
MUK71_00100	COG0515	serine threonine protein kinase
MUK71_00105	COG0515	serine threonine protein kinase
MUK71_00110	COG0768	penicillin binding
MUK71_00125	COG1716	ATPase activity
MUK71_00130	COG1716	ATPase activity
MUK71_00150	COG0346	lactoylglutathione lyase activity
MUK71_00160	COG3265	gluconokinase activity
MUK71_00165	COG2186	Transcriptional regulator
MUK71_00170	COG0783	Belongs to the Dps family
MUK71_00180	COG0723	plastoquinol--plastocyanin reductase activity
MUK71_00205	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MUK71_00235	COG1376	ErfK ybiS ycfS ynhG family protein
MUK71_00240	COG0702	epimerase
MUK71_00260	COG1063	alcohol dehydrogenase
MUK71_00265	COG1028	Short-chain dehydrogenase reductase Sdr
MUK71_00270	COG1609	Transcriptional regulator
MUK71_00300	COG0561	phosphatase activity
MUK71_00305	COG0671	phosphoesterase, PA-phosphatase related
MUK71_00310	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
MUK71_00315	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MUK71_00325	COG1929	Belongs to the glycerate kinase type-1 family
MUK71_00330	COG2233	PERMEase
MUK71_00340	COG1012	belongs to the aldehyde dehydrogenase family
MUK71_00345	COG2801	Transposase and inactivated derivatives
MUK71_00375	COG3104	oligopeptide transport
MUK71_00380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUK71_00390	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MUK71_00395	COG0077	Prephenate dehydratase
MUK71_00410	COG1597	lipid kinase activity
MUK71_00415	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MUK71_00420	COG0561	phosphatase activity
MUK71_00435	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MUK71_00440	COG2027	D-alanyl-D-alanine carboxypeptidase
MUK71_00450	COG0037	tRNA processing
MUK71_00460	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MUK71_00465	COG0302	gtp cyclohydrolase
MUK71_00470	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MUK71_00475	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MUK71_00505	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MUK71_00510	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MUK71_00530	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MUK71_00535	COG3237	CsbD-like
MUK71_00540	COG2376	Dihydroxyacetone kinase
MUK71_00545	COG1461	Dihydroxyacetone kinase
MUK71_00565	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MUK71_00580	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MUK71_00590	COG0581	inorganic phosphate transmembrane transporter activity
MUK71_00595	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MUK71_00600	COG0306	phosphate transporter
MUK71_00655	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MUK71_00685	COG2733	membrane
MUK71_00690	COG3387	PFAM Glycoside hydrolase 15-related
MUK71_00715	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MUK71_00720	COG0857	belongs to the CobB CobQ family
MUK71_00720	COG0280	phosphate acetyltransferase
MUK71_00725	COG0531	amino acid
MUK71_00735	COG4122	O-methyltransferase activity
MUK71_00755	COG2801	Transposase and inactivated derivatives
MUK71_00765	COG2252	PERMEase
MUK71_00845	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MUK71_00850	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MUK71_00865	COG0357	Ribosomal RNA small subunit methyltransferase G
MUK71_00865	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MUK71_00870	COG0191	fructose-bisphosphate aldolase activity
MUK71_00890	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MUK71_00900	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MUK71_00920	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MUK71_00935	COG1832	CoA-binding protein
MUK71_00950	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MUK71_00955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MUK71_00965	COG1116	anion transmembrane transporter activity
MUK71_00975	COG1832	CoA-binding protein
MUK71_00985	COG2315	Protein conserved in bacteria
MUK71_01000	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MUK71_01005	COG0047	phosphoribosylformylglycinamidine synthase activity
MUK71_01010	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MUK71_01040	COG2814	Major facilitator Superfamily
MUK71_01055	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MUK71_01060	COG1846	Transcriptional regulator
MUK71_01075	COG4555	ABC transporter
MUK71_01085	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MUK71_01120	COG3548	integral membrane protein
MUK71_01135	COG1136	(ABC) transporter
MUK71_01135	COG0577	efflux transmembrane transporter activity
MUK71_01145	COG2197	response regulator
MUK71_01155	COG0318	PFAM AMP-dependent synthetase and ligase
MUK71_01160	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MUK71_01165	COG3896	Chloramphenicol phosphotransferase-like protein
MUK71_01180	COG1335	isochorismatase
MUK71_01195	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MUK71_01200	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MUK71_01205	COG1802	Transcriptional regulator
MUK71_01265	COG0028	Belongs to the TPP enzyme family
MUK71_01295	COG2755	lipolytic protein G-D-S-L family
MUK71_01295	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MUK71_01325	COG1131	(ABC) transporter
MUK71_01370	COG3226	Transcriptional regulator
MUK71_01395	COG0702	epimerase
MUK71_01405	COG1309	transcriptional regulator
MUK71_01420	COG2814	Major facilitator Superfamily
MUK71_01445	COG2200	EAL domain
MUK71_01445	COG2771	luxR family
MUK71_01480	COG3246	L-lysine catabolic process to acetate
MUK71_01495	COG1176	ABC-type spermidine putrescine transport system, permease component I
MUK71_01500	COG1177	transmembrane transport
MUK71_01540	COG2764	glyoxalase bleomycin resistance protein dioxygenase
MUK71_01545	COG0384	phenazine biosynthesis protein PhzF
MUK71_01565	COG1028	Short-chain dehydrogenase reductase Sdr
MUK71_01580	COG0640	Transcriptional regulator
MUK71_01585	COG0798	PFAM Bile acid sodium symporter
MUK71_01590	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MUK71_01600	COG1063	alcohol dehydrogenase
MUK71_01605	COG2508	Transcriptional regulator
MUK71_01660	COG4585	Histidine kinase
MUK71_01665	COG2197	response regulator
MUK71_01705	COG0386	Belongs to the glutathione peroxidase family
MUK71_01730	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MUK71_01740	COG1396	sequence-specific DNA binding
MUK71_01745	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MUK71_01755	COG2314	TM2 domain
MUK71_01760	COG0351	phosphomethylpyrimidine kinase
MUK71_01785	COG0343	queuine tRNA-ribosyltransferase activity
MUK71_01825	COG1960	acyl-CoA dehydrogenase activity
MUK71_01840	COG3486	L-lysine 6-monooxygenase (NADPH) activity
MUK71_01860	COG0564	pseudouridine synthase activity
MUK71_01865	COG0659	secondary active sulfate transmembrane transporter activity
MUK71_01875	COG1846	Transcriptional regulator
MUK71_01885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MUK71_01890	COG1120	ATPase activity
MUK71_01900	COG0477	Major facilitator Superfamily
MUK71_01915	COG0583	DNA-binding transcription factor activity
MUK71_01920	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MUK71_01925	COG1201	RNA secondary structure unwinding
MUK71_01945	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MUK71_01960	COG3546	catalase activity
MUK71_01965	COG0515	serine threonine protein kinase
MUK71_01970	COG1674	ftsk spoiiie
MUK71_01970	COG0433	COG0433 Predicted ATPase
MUK71_02020	COG0590	tRNA wobble adenosine to inosine editing
MUK71_02025	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MUK71_02035	COG2062	phosphohistidine phosphatase, SixA
MUK71_02040	COG1511	domain protein
MUK71_02060	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
MUK71_02075	COG0514	ATP-dependent DNA helicase (RecQ)
MUK71_02080	COG2267	carboxylic ester hydrolase activity
MUK71_02090	COG1024	Enoyl-CoA hydratase
MUK71_02100	COG0667	Aldo Keto reductase
MUK71_02115	COG1505	serine-type exopeptidase activity
MUK71_02150	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
MUK71_02165	COG3250	beta-galactosidase activity
MUK71_02180	COG1175	transmembrane transport
MUK71_02185	COG0395	ABC-type sugar transport system, permease component
MUK71_02195	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MUK71_02210	COG2072	flavoprotein involved in K transport
MUK71_02225	COG0604	alcohol dehydrogenase
MUK71_02230	COG1966	Carbon starvation protein
MUK71_02255	COG0656	L-ascorbic acid biosynthetic process
MUK71_02260	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MUK71_02285	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MUK71_02305	COG1815	bacterial-type flagellum-dependent cell motility
MUK71_02315	COG1677	Flagellar hook-basal body complex protein FliE
MUK71_02320	COG1766	The M ring may be actively involved in energy transduction
MUK71_02325	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MUK71_02335	COG1157	protein secretion by the type III secretion system
MUK71_02345	COG0791	NLP P60 protein
MUK71_02355	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
MUK71_02370	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MUK71_02375	COG1360	Flagellar Motor Protein
MUK71_02385	COG1776	CheC inhibitor of MCP methylation
MUK71_02385	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MUK71_02395	COG1338	Plays a role in the flagellum-specific transport system
MUK71_02410	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MUK71_02425	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MUK71_02445	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MUK71_02450	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MUK71_02455	COG0626	cystathionine gamma-synthase activity
MUK71_02470	COG0588	phosphoglycerate mutase activity
MUK71_02480	COG5002	protein histidine kinase activity
MUK71_02485	COG0745	RESPONSE REGULATOR receiver
MUK71_02500	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MUK71_02505	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
MUK71_02510	COG0215	cysteine-tRNA ligase activity
MUK71_02515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MUK71_02530	COG0366	Alpha amylase catalytic
MUK71_02535	COG0366	Alpha amylase catalytic
MUK71_02540	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MUK71_02585	COG0277	FAD linked oxidase domain protein
MUK71_02590	COG0366	Alpha amylase catalytic
MUK71_02605	COG3842	ATPase activity
MUK71_02615	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
MUK71_02650	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MUK71_02655	COG0477	Major facilitator Superfamily
MUK71_02660	COG1957	nucleoside hydrolase
MUK71_02665	COG0318	PFAM AMP-dependent synthetase and ligase
MUK71_02735	COG1028	Short-chain dehydrogenase reductase Sdr
MUK71_02750	COG2365	Tyrosine phosphatase family
MUK71_02790	COG1609	Transcriptional regulator
MUK71_02795	COG0366	Alpha amylase catalytic
MUK71_02805	COG1175	transmembrane transport
MUK71_02810	COG3833	ABC-type maltose transport systems, permease component
MUK71_02815	COG0667	Aldo Keto reductase
MUK71_02845	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MUK71_02875	COG0459	protein refolding
MUK71_02885	COG2205	protein histidine kinase activity
MUK71_02890	COG0745	RESPONSE REGULATOR receiver
MUK71_02910	COG1278	Cold shock
MUK71_02920	COG2814	Major facilitator Superfamily
MUK71_02935	COG0741	lytic transglycosylase activity
MUK71_02935	COG1196	nuclear chromosome segregation
MUK71_02935	COG0739	heme binding
MUK71_02965	COG0303	'Molybdopterin
MUK71_02970	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MUK71_02975	COG5002	protein histidine kinase activity
MUK71_02980	COG1132	(ABC) transporter
MUK71_02985	COG0363	glucosamine-6-phosphate deaminase activity
MUK71_02995	COG0191	fructose-bisphosphate aldolase activity
MUK71_03000	COG1105	Belongs to the carbohydrate kinase PfkB family
MUK71_03010	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MUK71_03025	COG0395	ABC-type sugar transport system, permease component
MUK71_03050	COG0483	inositol monophosphate 1-phosphatase activity
MUK71_03060	COG0045	succinate-CoA ligase (ADP-forming) activity
MUK71_03070	COG2814	Major facilitator Superfamily
MUK71_03080	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MUK71_03090	COG0318	PFAM AMP-dependent synthetase and ligase
MUK71_03100	COG1396	sequence-specific DNA binding
MUK71_03115	COG0028	Belongs to the TPP enzyme family
MUK71_03145	COG0514	ATP-dependent DNA helicase (RecQ)
MUK71_03210	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MUK71_03225	COG0730	response to heat
MUK71_03230	COG3265	gluconokinase activity
MUK71_03235	COG2610	gluconate transmembrane transporter activity
MUK71_03255	COG0596	Alpha beta hydrolase
MUK71_03280	COG3387	PFAM Glycoside hydrolase 15-related
MUK71_03285	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MUK71_03330	COG0640	Transcriptional regulator
MUK71_03345	COG1454	alcohol dehydrogenase
MUK71_03355	COG2814	Major facilitator Superfamily
MUK71_03365	COG4213	ABC transporter substrate-binding protein
MUK71_03370	COG1129	ABC transporter
MUK71_03375	COG4214	carbohydrate transport
MUK71_03395	COG0583	DNA-binding transcription factor activity
MUK71_03405	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MUK71_03415	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MUK71_03420	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MUK71_03430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MUK71_03440	COG1028	Short-chain dehydrogenase reductase Sdr
MUK71_03445	COG1063	alcohol dehydrogenase
MUK71_03455	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MUK71_03465	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MUK71_03485	COG2301	Belongs to the HpcH HpaI aldolase family
MUK71_03530	COG3573	Dehydrogenase
MUK71_03535	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MUK71_03545	COG2079	MmgE PrpD family protein
MUK71_03550	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MUK71_03560	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
MUK71_03675	COG2235	arginine
MUK71_03725	COG1879	ABC-type sugar transport system periplasmic component
MUK71_03730	COG1129	ABC transporter
MUK71_03735	COG1172	Belongs to the binding-protein-dependent transport system permease family
MUK71_03740	COG1940	carbohydrate kinase activity
MUK71_03755	COG0252	asparaginase activity
MUK71_03770	COG1028	Short-chain dehydrogenase reductase Sdr
MUK71_03775	COG1028	Short-chain dehydrogenase reductase Sdr
MUK71_03805	COG1960	acyl-CoA dehydrogenase activity
MUK71_03815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MUK71_03890	COG1358	cellular component organization or biogenesis
MUK71_03950	COG1595	DNA-templated transcription, initiation
MUK71_03985	COG0583	DNA-binding transcription factor activity
MUK71_03990	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MUK71_03995	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MUK71_04000	COG1028	Short-chain dehydrogenase reductase Sdr
MUK71_04005	COG1024	Enoyl-CoA hydratase
MUK71_04010	COG1250	3-hydroxyacyl-CoA dehydrogenase
MUK71_04015	COG2801	Transposase and inactivated derivatives
MUK71_04030	COG0824	Thioesterase
MUK71_04035	COG1024	Enoyl-CoA hydratase
MUK71_04040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MUK71_04045	COG1940	carbohydrate kinase activity
MUK71_04050	COG2115	Belongs to the xylose isomerase family
MUK71_04055	COG1070	Carbohydrate kinase
MUK71_04060	COG2017	converts alpha-aldose to the beta-anomer
MUK71_04075	COG3458	cephalosporin-C deacetylase activity
MUK71_04080	COG1472	Belongs to the glycosyl hydrolase 3 family
MUK71_04090	COG1175	transmembrane transport
MUK71_04095	COG1653	transport
MUK71_04100	COG1609	Transcriptional regulator
MUK71_04110	COG0584	glycerophosphoryl diester phosphodiesterase
MUK71_04120	COG2390	Transcriptional regulator
MUK71_04125	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MUK71_04130	COG0738	Major facilitator superfamily
MUK71_04145	COG1175	transmembrane transport
MUK71_04150	COG0395	ABC-type sugar transport system, permease component
MUK71_04165	COG2814	Major facilitator Superfamily
MUK71_04170	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MUK71_04180	COG0667	Aldo Keto reductase
MUK71_04200	COG0247	lactate metabolic process
MUK71_04205	COG1139	Iron-sulfur cluster binding protein
MUK71_04210	COG1556	Lactate utilization protein
MUK71_04225	COG3619	membrane
MUK71_04230	COG0405	Gamma-glutamyltransferase
MUK71_04235	COG0039	L-malate dehydrogenase activity
MUK71_04240	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MUK71_04255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUK71_04265	COG2323	membrane
MUK71_04270	COG1278	Cold shock
MUK71_04275	COG2066	Belongs to the glutaminase family
MUK71_04275	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
MUK71_04280	COG1278	Cold shock
MUK71_04285	COG2186	Transcriptional regulator
MUK71_04290	COG0531	amino acid
MUK71_04300	COG2815	serine threonine protein kinase
MUK71_04300	COG0515	serine threonine protein kinase
MUK71_04305	COG3012	SEC-C Motif Domain Protein
MUK71_04310	COG1063	alcohol dehydrogenase
MUK71_04315	COG1063	alcohol dehydrogenase
MUK71_04345	COG0366	Alpha amylase catalytic
MUK71_04350	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
MUK71_04360	COG0829	nickel cation binding
MUK71_04365	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MUK71_04375	COG0804	urea catabolic process
MUK71_04380	COG0832	Belongs to the urease beta subunit family
MUK71_04385	COG0831	urea catabolic process
MUK71_04410	COG0753	catalase activity
MUK71_04490	COG0477	Major facilitator Superfamily
MUK71_04500	COG0138	bifunctional purine biosynthesis protein purh
MUK71_04510	COG0385	Bile acid
MUK71_04555	COG4214	carbohydrate transport
MUK71_04585	COG2072	flavoprotein involved in K transport
MUK71_04590	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MUK71_04595	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MUK71_04625	COG0708	Exodeoxyribonuclease III
MUK71_04630	COG0180	Tryptophanyl-tRNA synthetase
MUK71_04645	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MUK71_04660	COG2009	succinate dehydrogenase
MUK71_04670	COG1473	amidohydrolase
MUK71_04670	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
MUK71_04675	COG1744	ABC transporter substrate-binding protein PnrA-like
MUK71_04680	COG3845	ABC transporter
MUK71_04685	COG4603	Belongs to the binding-protein-dependent transport system permease family
MUK71_04690	COG1079	Belongs to the binding-protein-dependent transport system permease family
MUK71_04710	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MUK71_04715	COG3956	TIGRFAM MazG family protein
MUK71_04720	COG0148	phosphopyruvate hydratase activity
MUK71_04745	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MUK71_04780	COG0559	Belongs to the binding-protein-dependent transport system permease family
MUK71_04795	COG2017	converts alpha-aldose to the beta-anomer
MUK71_04805	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MUK71_04810	COG0705	Rhomboid family
MUK71_04815	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MUK71_04825	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MUK71_04835	COG1331	Highly conserved protein containing a thioredoxin domain
MUK71_04845	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MUK71_04850	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
MUK71_04865	COG0477	Major facilitator Superfamily
MUK71_04875	COG0114	fumarate hydratase activity
MUK71_04890	COG1494	fructose-1,6-bisphosphatase
MUK71_04905	COG1482	cell wall glycoprotein biosynthetic process
MUK71_04910	COG1316	TRANSCRIPTIONal
MUK71_04965	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MUK71_04985	COG1022	Amp-dependent synthetase and ligase
MUK71_05015	COG0714	Associated with various cellular activities
MUK71_05020	COG0084	hydrolase, TatD family'
MUK71_05040	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MUK71_05045	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MUK71_05050	COG0488	(ABC) transporter
MUK71_05070	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MUK71_05075	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MUK71_05080	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MUK71_05085	COG0193	aminoacyl-tRNA hydrolase activity
MUK71_05160	COG1192	Involved in chromosome partitioning
MUK71_05185	COG0822	iron-sulfur transferase activity
MUK71_05195	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MUK71_05200	COG5002	protein histidine kinase activity
MUK71_05205	COG0745	RESPONSE REGULATOR receiver
MUK71_05210	COG5002	protein histidine kinase activity
MUK71_05255	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MUK71_05295	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MUK71_05325	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MUK71_05340	COG0477	Major facilitator Superfamily
MUK71_05345	COG4770	biotin carboxylase activity
MUK71_05355	COG0424	maF-like protein
MUK71_05360	COG1823	symporter activity
MUK71_05375	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MUK71_05400	COG0631	protein serine/threonine phosphatase activity
MUK71_05415	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MUK71_05430	COG2226	methyltransferase
MUK71_05440	COG0456	acetyltransferase
MUK71_05445	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MUK71_05450	COG0154	amidase activity
MUK71_05455	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MUK71_05470	COG1175	transmembrane transport
MUK71_05475	COG0395	ABC-type sugar transport system, permease component
MUK71_05480	COG4948	Mandelate Racemase Muconate Lactonizing
MUK71_05485	COG0800	Aldolase
MUK71_05500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MUK71_05510	COG1254	Belongs to the acylphosphatase family
MUK71_05515	COG2986	histidine ammonia-lyase
MUK71_05525	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MUK71_05530	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MUK71_05540	COG1228	amidohydrolase
MUK71_05555	COG3250	beta-galactosidase activity
MUK71_05570	COG2873	o-acetylhomoserine
MUK71_05575	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MUK71_05610	COG0423	glycine-tRNA ligase activity
MUK71_05625	COG2031	fatty acid transporter
MUK71_05645	COG0358	DNA primase activity
MUK71_05660	COG1301	dicarboxylic acid transport
MUK71_05670	COG0477	Major facilitator Superfamily
MUK71_05680	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MUK71_05690	COG0297	glycogen (starch) synthase activity
MUK71_05700	COG1960	acyl-CoA dehydrogenase activity
MUK71_05710	COG0052	Belongs to the universal ribosomal protein uS2 family
MUK71_05715	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MUK71_05720	COG0528	UMP kinase activity
MUK71_05725	COG0233	cytoplasmic translational termination
MUK71_05730	COG0575	Belongs to the CDS family
MUK71_05740	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MUK71_05750	COG3279	Response regulator of the LytR AlgR family
MUK71_05755	COG3275	phosphorelay sensor kinase activity
MUK71_05765	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MUK71_05800	COG0022	dehydrogenase e1 component
MUK71_05805	COG0508	dehydrogenase complex catalyzes the overall conversion of
MUK71_05815	COG1309	transcriptional regulator
MUK71_05820	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MUK71_05830	COG1960	acyl-CoA dehydrogenase activity
MUK71_05860	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MUK71_05865	COG0750	zinc metalloprotease
MUK71_05885	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MUK71_05895	COG0442	prolyl-tRNA aminoacylation
MUK71_05905	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
MUK71_05915	COG0779	Required for maturation of 30S ribosomal subunits
MUK71_05920	COG0195	Participates in both transcription termination and antitermination
MUK71_05930	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MUK71_05935	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MUK71_05940	COG0436	Aminotransferase
MUK71_05945	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MUK71_05965	COG0196	riboflavin kinase activity
MUK71_05970	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MUK71_05975	COG1185	polyribonucleotide nucleotidyltransferase activity
MUK71_05980	COG0612	Peptidase, M16
MUK71_05995	COG0725	ABC transporter, periplasmic molybdate-binding protein
MUK71_06020	COG0521	Mo-molybdopterin cofactor biosynthetic process
MUK71_06030	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MUK71_06045	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MUK71_06050	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MUK71_06055	COG1674	ftsk spoiiie
MUK71_06065	COG1546	Belongs to the CinA family
MUK71_06065	COG1058	Belongs to the CinA family
MUK71_06070	COG1396	sequence-specific DNA binding
MUK71_06090	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MUK71_06095	COG2137	regulation of response to DNA damage stimulus
MUK71_06110	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MUK71_06115	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MUK71_06120	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MUK71_06125	COG2813	Specifically methylates the guanine in position
MUK71_06130	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MUK71_06140	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MUK71_06150	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MUK71_06155	COG0131	Imidazoleglycerol-phosphate dehydratase
MUK71_06160	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MUK71_06170	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MUK71_06190	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MUK71_06195	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MUK71_06200	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MUK71_06205	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MUK71_06210	COG2814	Major facilitator Superfamily
MUK71_06230	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MUK71_06235	COG0072	phenylalanine-tRNA ligase activity
MUK71_06235	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MUK71_06250	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MUK71_06255	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MUK71_06260	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MUK71_06265	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MUK71_06270	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MUK71_06275	COG1438	arginine binding
MUK71_06280	COG0137	argininosuccinate synthase activity
MUK71_06285	COG0165	Argininosuccinate lyase
MUK71_06290	COG0259	pyridoxamine-phosphate oxidase activity
MUK71_06300	COG2094	Belongs to the DNA glycosylase MPG family
MUK71_06310	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MUK71_06320	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MUK71_06350	COG0647	UMP catabolic process
MUK71_06365	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MUK71_06370	COG0497	DNA recombination
MUK71_06375	COG0504	CTP synthase activity
MUK71_06380	COG0494	nUDIX hydrolase
MUK71_06390	COG0494	nUDIX hydrolase
MUK71_06400	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MUK71_06405	COG2079	MmgE PrpD family protein
MUK71_06420	COG4565	transcriptional regulatory protein
MUK71_06425	COG3290	protein histidine kinase activity
MUK71_06430	COG1301	dicarboxylic acid transport
MUK71_06445	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MUK71_06450	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MUK71_06460	COG0287	Prephenate dehydrogenase
MUK71_06465	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MUK71_06470	COG1160	GTP binding
MUK71_06485	COG2133	pyrroloquinoline quinone binding
MUK71_06495	COG1716	ATPase activity
MUK71_06520	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MUK71_06535	COG1940	carbohydrate kinase activity
MUK71_06555	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
MUK71_06560	COG0515	serine threonine protein kinase
MUK71_06560	COG2815	serine threonine protein kinase
MUK71_06565	COG1388	LysM domain
MUK71_06565	COG3942	CHAP domain
MUK71_06575	COG0142	geranyltranstransferase activity
MUK71_06585	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MUK71_06595	COG2001	Belongs to the MraZ family
MUK71_06600	COG0275	rRNA processing
MUK71_06610	COG0768	penicillin binding
MUK71_06625	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MUK71_06630	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MUK71_06640	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MUK71_06645	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MUK71_06655	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MUK71_06660	COG1496	oxidoreductase activity
MUK71_06665	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MUK71_06670	COG1799	cell septum assembly
MUK71_06680	COG3599	regulation of cell shape
MUK71_06685	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MUK71_06695	COG0587	DNA-directed DNA polymerase activity
MUK71_06700	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MUK71_06705	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MUK71_06725	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
MUK71_06730	COG0174	glutamine synthetase
MUK71_06735	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
MUK71_06740	COG0765	amino acid transport
MUK71_06745	COG1126	abc transporter atp-binding protein
MUK71_06755	COG0277	FAD linked oxidase domain protein
MUK71_06765	COG2382	esterase
MUK71_06770	COG1120	ATPase activity
MUK71_06775	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MUK71_06780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MUK71_06785	COG4592	Periplasmic binding protein
MUK71_06830	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MUK71_06835	COG0321	lipoyl(octanoyl) transferase activity
MUK71_06840	COG2815	serine threonine protein kinase
MUK71_06840	COG0515	serine threonine protein kinase
MUK71_06845	COG0793	Belongs to the peptidase S41A family
MUK71_06845	COG4946	Tricorn protease homolog
MUK71_06850	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MUK71_06855	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MUK71_06865	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
MUK71_06870	COG0829	nickel cation binding
MUK71_06875	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MUK71_06880	COG0830	nickel cation binding
MUK71_06885	COG0804	urea catabolic process
MUK71_06890	COG0832	Belongs to the urease beta subunit family
MUK71_06900	COG0831	urea catabolic process
MUK71_06905	COG1764	response to oxidative stress
MUK71_06915	COG0508	dehydrogenase complex catalyzes the overall conversion of
MUK71_06920	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MUK71_06925	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MUK71_06945	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MUK71_06955	COG0187	DNA topoisomerase II activity
MUK71_06965	COG0501	Belongs to the peptidase M48B family
MUK71_06975	COG1271	oxidase subunit
MUK71_06980	COG1294	oxidase, subunit
MUK71_06985	COG4988	ABC transporter
MUK71_07000	COG1937	Protein conserved in bacteria
MUK71_07015	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MUK71_07030	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MUK71_07035	COG1435	thymidine kinase activity
MUK71_07055	COG0756	dUTP diphosphatase activity
MUK71_07080	COG0569	domain protein
MUK71_07085	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MUK71_07090	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MUK71_07095	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MUK71_07110	COG0667	Aldo Keto reductase
MUK71_07125	COG4221	oxidoreductase activity
MUK71_07130	COG1250	3-hydroxyacyl-CoA dehydrogenase
MUK71_07130	COG1024	Enoyl-CoA hydratase
MUK71_07135	COG0183	Belongs to the thiolase family
MUK71_07140	COG0657	acetylesterase activity
MUK71_07150	COG4566	intracellular signal transduction
MUK71_07215	COG2318	DinB family
MUK71_07255	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MUK71_07260	COG0183	Belongs to the thiolase family
MUK71_07280	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
MUK71_07285	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
MUK71_07305	COG1269	ATP hydrolysis coupled proton transport
MUK71_07325	COG0024	Methionine aminopeptidase
MUK71_07335	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MUK71_07365	COG0500	methyltransferase
MUK71_07370	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MUK71_07455	COG0242	peptide deformylase activity
MUK71_07460	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MUK71_07470	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MUK71_07490	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MUK71_07490	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MUK71_07495	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MUK71_07495	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MUK71_07500	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MUK71_07510	COG4335	DNA alkylation repair
MUK71_07515	COG2315	Protein conserved in bacteria
MUK71_07525	COG0477	Major facilitator Superfamily
MUK71_07535	COG0477	Major facilitator Superfamily
MUK71_07570	COG3795	YCII-related domain
MUK71_07575	COG0140	phosphoribosyl-ATP diphosphatase activity
MUK71_07580	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MUK71_07585	COG0107	imidazoleglycerol-phosphate synthase activity
MUK71_07590	COG0456	acetyltransferase
MUK71_07590	COG0454	-acetyltransferase
MUK71_07605	COG1064	alcohol dehydrogenase
MUK71_07645	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
MUK71_07695	COG2354	Protein conserved in bacteria
MUK71_07705	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MUK71_07725	COG0134	indole-3-glycerol-phosphate synthase activity
MUK71_07730	COG0133	tryptophan synthase activity
MUK71_07735	COG0159	tryptophan synthase activity
MUK71_07745	COG0070	glutamate synthase
MUK71_07745	COG0069	glutamate synthase activity
MUK71_07745	COG0067	glutamate synthase
MUK71_07800	COG1953	Uracil, thiamine, allantoin
MUK71_07815	COG0789	Transcriptional regulator
MUK71_07850	COG1595	DNA-templated transcription, initiation
MUK71_07880	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MUK71_07890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MUK71_07895	COG2814	Major facilitator Superfamily
MUK71_07920	COG2124	cytochrome p450
MUK71_07930	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MUK71_07935	COG1309	transcriptional regulator
MUK71_07940	COG0778	Nitroreductase
MUK71_07945	COG1609	Transcriptional regulator
MUK71_07950	COG1329	Transcriptional regulator
MUK71_07955	COG1643	Atp-dependent helicase
MUK71_07980	COG2814	Major facilitator Superfamily
MUK71_07990	COG1960	acyl-CoA dehydrogenase activity
MUK71_08020	COG0488	(ABC) transporter
MUK71_08035	COG1785	Belongs to the alkaline phosphatase family
MUK71_08040	COG0009	L-threonylcarbamoyladenylate synthase
MUK71_08045	COG2267	carboxylic ester hydrolase activity
MUK71_08065	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MUK71_08070	COG4499	WXG100 protein secretion system (Wss), protein YukC
MUK71_08070	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MUK71_08080	COG1028	Short-chain dehydrogenase reductase Sdr
MUK71_08090	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
MUK71_08095	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
MUK71_08100	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
MUK71_08115	COG0791	NLP P60 protein
MUK71_08115	COG1388	LysM domain
MUK71_08115	COG3103	Sh3 type 3 domain protein
MUK71_08130	COG0425	Belongs to the sulfur carrier protein TusA family
MUK71_08135	COG2391	methyltransferase activity
MUK71_08155	COG1028	Short-chain dehydrogenase reductase Sdr
MUK71_08165	COG2272	Belongs to the type-B carboxylesterase lipase family
MUK71_08175	COG0488	(ABC) transporter
MUK71_08185	COG2272	Belongs to the type-B carboxylesterase lipase family
MUK71_08200	COG1607	acyl-coa hydrolase
MUK71_08205	COG0438	transferase activity, transferring glycosyl groups
MUK71_08225	COG1472	Belongs to the glycosyl hydrolase 3 family
MUK71_08230	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MUK71_08235	COG0477	Major facilitator Superfamily
MUK71_08240	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MUK71_08245	COG1082	Xylose isomerase domain protein TIM barrel
MUK71_08245	COG3185	4-Hydroxyphenylpyruvate dioxygenase
MUK71_08250	COG1414	Transcriptional regulator
MUK71_08260	COG0531	amino acid
MUK71_08265	COG0076	glutamate decarboxylase activity
MUK71_08275	COG2814	Major facilitator Superfamily
MUK71_08290	COG1902	pentaerythritol trinitrate reductase activity
MUK71_08295	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MUK71_08300	COG2050	protein possibly involved in aromatic compounds catabolism
MUK71_08310	COG4552	Acetyltransferase involved in intracellular survival and related
MUK71_08315	COG0539	negative regulation of cytoplasmic translation
MUK71_08335	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MUK71_08345	COG2723	6-phospho-beta-galactosidase activity
MUK71_08355	COG1175	transmembrane transport
MUK71_08365	COG2813	Specifically methylates the guanine in position
MUK71_08370	COG1739	Uncharacterized protein family UPF0029
MUK71_08375	COG0237	dephospho-CoA kinase activity
MUK71_08375	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MUK71_08380	COG0556	nucleotide-excision repair
MUK71_08415	COG4106	trans-aconitate 2-methyltransferase activity
MUK71_08425	COG0531	amino acid
MUK71_08455	COG0546	phosphoglycolate phosphatase activity
MUK71_08460	COG0204	Acyl-transferase
MUK71_08460	COG0318	PFAM AMP-dependent synthetase and ligase
MUK71_08465	COG0322	excinuclease ABC activity
MUK71_08470	COG1660	Displays ATPase and GTPase activities
MUK71_08475	COG0391	Required for morphogenesis under gluconeogenic growth conditions
MUK71_08480	COG1481	regulation of sporulation
MUK71_08495	COG0126	phosphoglycerate kinase activity
MUK71_08500	COG0149	triose-phosphate isomerase activity
MUK71_08505	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MUK71_08510	COG0363	glucosamine-6-phosphate deaminase activity
MUK71_08530	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MUK71_08540	COG0109	protoheme IX farnesyltransferase activity
MUK71_08545	COG1612	heme a metabolic process
MUK71_08555	COG1131	(ABC) transporter
MUK71_08575	COG0396	ATPase activity
MUK71_08580	COG2151	metal-sulfur cluster biosynthetic enzyme
MUK71_08590	COG1011	Hydrolase
MUK71_08600	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MUK71_08605	COG1122	ATPase activity
MUK71_08610	COG1268	BioY protein
MUK71_08615	COG0488	(ABC) transporter
MUK71_08640	COG1028	Short-chain dehydrogenase reductase Sdr
MUK71_08645	COG1028	Short-chain dehydrogenase reductase Sdr
MUK71_08650	COG0560	Phosphoserine phosphatase
MUK71_08650	COG3830	Belongs to the UPF0237 family
MUK71_08655	COG1119	ATPase activity
MUK71_08670	COG0254	rRNA binding
MUK71_08695	COG2855	membrane
MUK71_08700	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MUK71_08710	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MUK71_08715	COG0297	glycogen (starch) synthase activity
MUK71_08725	COG1309	transcriptional regulator
MUK71_08730	COG0183	Belongs to the thiolase family
MUK71_08735	COG1028	Short-chain dehydrogenase reductase Sdr
MUK71_08745	COG3844	kynureninase activity
MUK71_08750	COG0589	response to stress
MUK71_08760	COG1253	flavin adenine dinucleotide binding
MUK71_08765	COG0628	permease
MUK71_08775	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MUK71_08795	COG1968	undecaprenyl-diphosphatase activity
MUK71_08800	COG0215	cysteine-tRNA ligase activity
MUK71_08810	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MUK71_08825	COG1222	aaa ATPase
MUK71_08830	COG4122	O-methyltransferase activity
MUK71_08840	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
MUK71_08845	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
MUK71_08850	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
MUK71_08855	COG0545	Peptidyl-prolyl cis-trans isomerase
MUK71_08875	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MUK71_08880	COG0805	protein transport
MUK71_08890	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MUK71_08895	COG1216	Glycosyl transferase, family 2
MUK71_08920	COG0823	Involved in the tonB-independent uptake of proteins
MUK71_08920	COG1506	peptidase
MUK71_08920	COG4946	Tricorn protease homolog
MUK71_08925	COG0242	peptide deformylase activity
MUK71_08955	COG0366	Alpha amylase catalytic
MUK71_08965	COG1028	Short-chain dehydrogenase reductase Sdr
MUK71_08980	COG1136	(ABC) transporter
MUK71_09000	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MUK71_09005	COG1845	cytochrome c oxidase, subunit III
MUK71_09010	COG2010	Cytochrome c
MUK71_09015	COG0723	plastoquinol--plastocyanin reductase activity
MUK71_09020	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MUK71_09030	COG2188	Transcriptional regulator
MUK71_09035	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MUK71_09045	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MUK71_09050	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MUK71_09070	COG0167	dihydroorotate dehydrogenase activity
MUK71_09080	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MUK71_09085	COG1381	Involved in DNA repair and RecF pathway recombination
MUK71_09090	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MUK71_09095	COG1316	TRANSCRIPTIONal
MUK71_09100	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MUK71_09110	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MUK71_09130	COG0484	heat shock protein binding
MUK71_09135	COG1420	regulation of RNA biosynthetic process
MUK71_09155	COG0481	GTPase activity
MUK71_09165	COG0268	Binds directly to 16S ribosomal RNA
MUK71_09185	COG1307	EDD domain protein, DegV family
MUK71_09190	COG0495	leucyl-tRNA aminoacylation
MUK71_09195	COG1595	DNA-templated transcription, initiation
MUK71_09200	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MUK71_09205	COG0385	Bile acid
MUK71_09210	COG2072	flavoprotein involved in K transport
MUK71_09215	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MUK71_09220	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MUK71_09225	COG0656	L-ascorbic acid biosynthetic process
MUK71_09230	COG0596	Alpha beta hydrolase
MUK71_09235	COG0438	transferase activity, transferring glycosyl groups
MUK71_09240	COG2130	NADP-dependent
MUK71_09245	COG1846	Transcriptional regulator
MUK71_09270	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MUK71_09280	COG1758	RNA polymerase activity
MUK71_09285	COG0194	GDP metabolic process
MUK71_09290	COG0194	GDP metabolic process
MUK71_09295	COG0284	orotidine-5'-phosphate decarboxylase activity
MUK71_09300	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MUK71_09305	COG0505	Belongs to the CarA family
MUK71_09315	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MUK71_09320	COG0540	Belongs to the ATCase OTCase family
MUK71_09325	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MUK71_09335	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MUK71_09340	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MUK71_09345	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MUK71_09355	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MUK71_09360	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MUK71_09370	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MUK71_09375	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MUK71_09390	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MUK71_09410	COG0384	phenazine biosynthesis protein PhzF
MUK71_09415	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MUK71_09425	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MUK71_09430	COG0124	histidyl-tRNA synthetase
MUK71_09440	COG1196	nuclear chromosome segregation
MUK71_09450	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MUK71_09455	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MUK71_09460	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MUK71_09470	COG2255	four-way junction helicase activity
MUK71_09475	COG0632	four-way junction helicase activity
MUK71_09480	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MUK71_09485	COG0217	transcriptional regulatory protein
MUK71_09490	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MUK71_09495	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MUK71_09515	COG2226	methyltransferase
MUK71_09545	COG0339	signal peptide processing
MUK71_09550	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MUK71_09555	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MUK71_09565	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MUK71_09570	COG0587	DNA-directed DNA polymerase activity
MUK71_09625	COG2409	Drug exporters of the RND superfamily
MUK71_09660	COG0346	lactoylglutathione lyase activity
MUK71_09690	COG0667	Aldo Keto reductase
MUK71_09695	COG2135	peptidase activity
MUK71_09730	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MUK71_09750	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MUK71_09800	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MUK71_09820	COG0583	DNA-binding transcription factor activity
MUK71_09875	COG3201	nicotinamide mononucleotide transporter
MUK71_09890	COG0406	alpha-ribazole phosphatase activity
MUK71_09905	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MUK71_09915	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MUK71_09920	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MUK71_09925	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MUK71_09930	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MUK71_09935	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MUK71_09940	COG1530	ribonuclease E activity
MUK71_09960	COG0105	UTP biosynthetic process
MUK71_09970	COG0285	dihydrofolate synthase activity
MUK71_09975	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MUK71_09990	COG3189	MarR family transcriptional regulator
MUK71_09995	COG0525	valine-tRNA ligase activity
MUK71_10000	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MUK71_10005	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MUK71_10010	COG0740	serine-type endopeptidase activity
MUK71_10020	COG0544	peptidyl-prolyl cis-trans isomerase activity
MUK71_10060	COG0668	transmembrane transport
MUK71_10080	COG1946	Acyl-CoA thioesterase
MUK71_10095	COG0629	single-stranded DNA binding
MUK71_10165	COG0242	peptide deformylase activity
MUK71_10185	COG3022	response to hydroperoxide
MUK71_10195	COG1579	Zn-ribbon protein possibly nucleic acid-binding
MUK71_10200	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MUK71_10205	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MUK71_10215	COG1045	serine acetyltransferase
MUK71_10220	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MUK71_10250	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
MUK71_10265	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MUK71_10270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MUK71_10275	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MUK71_10285	COG4974	Belongs to the 'phage' integrase family
MUK71_10310	COG0792	nuclease activity
MUK71_10335	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MUK71_10340	COG0681	Belongs to the peptidase S26 family
MUK71_10345	COG0681	Belongs to the peptidase S26 family
MUK71_10350	COG0335	large ribosomal subunit rRNA binding
MUK71_10355	COG0336	Belongs to the RNA methyltransferase TrmD family
MUK71_10360	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MUK71_10365	COG1837	Belongs to the UPF0109 family
MUK71_10370	COG0228	four-way junction DNA binding
MUK71_10375	COG2514	catechol 2,3-dioxygenase activity
MUK71_10380	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MUK71_10400	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MUK71_10420	COG0477	Major facilitator Superfamily
MUK71_10430	COG1196	nuclear chromosome segregation
MUK71_10435	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MUK71_10440	COG0318	PFAM AMP-dependent synthetase and ligase
MUK71_10445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MUK71_10450	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MUK71_10460	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MUK71_10465	COG0571	ribonuclease III activity
MUK71_10470	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MUK71_10485	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MUK71_10500	COG0742	ribosomal rna small subunit methyltransferase
MUK71_10510	COG1461	Dihydroxyacetone kinase
MUK71_10515	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MUK71_10530	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MUK71_10535	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MUK71_10540	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MUK71_10545	COG1215	transferase activity, transferring glycosyl groups
MUK71_10545	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MUK71_10550	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MUK71_10555	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MUK71_10565	COG1134	teichoic acid transport
MUK71_10570	COG1682	transport, permease protein
MUK71_10585	COG1316	TRANSCRIPTIONal
MUK71_10600	COG1181	Belongs to the D-alanine--D-alanine ligase family
MUK71_10605	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MUK71_10615	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MUK71_10620	COG0066	3-isopropylmalate dehydratase activity
MUK71_10625	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MUK71_10630	COG1414	Transcriptional regulator
MUK71_10660	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MUK71_10690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MUK71_10695	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MUK71_10700	COG0473	3-isopropylmalate dehydrogenase activity
MUK71_10705	COG4585	Histidine kinase
MUK71_10710	COG2197	response regulator
MUK71_10725	COG0577	efflux transmembrane transporter activity
MUK71_10725	COG1136	(ABC) transporter
MUK71_10750	COG0577	efflux transmembrane transporter activity
MUK71_10750	COG1136	(ABC) transporter
MUK71_10755	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MUK71_10760	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MUK71_10765	COG0440	acetolactate synthase activity
MUK71_10775	COG0129	dihydroxy-acid dehydratase activity
MUK71_10785	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MUK71_10805	COG1690	Belongs to the RtcB family
MUK71_10825	COG0747	negative chemotaxis
MUK71_10830	COG0601	transmembrane transport
MUK71_10835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MUK71_10845	COG4172	Belongs to the ABC transporter superfamily
MUK71_10850	COG0747	negative chemotaxis
MUK71_10855	COG0579	oxidoreductase
MUK71_10860	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MUK71_10870	COG1846	Transcriptional regulator
MUK71_10875	COG2814	Major facilitator Superfamily
MUK71_10880	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MUK71_10885	COG1104	cysteine desulfurase activity
MUK71_10895	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MUK71_10900	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MUK71_10915	COG1113	amino acid transport
MUK71_10925	COG0022	dehydrogenase e1 component
MUK71_10930	COG0508	dehydrogenase complex catalyzes the overall conversion of
MUK71_10940	COG0515	serine threonine protein kinase
MUK71_10955	COG0419	ATPase involved in DNA repair
MUK71_10960	COG0420	3'-5' exonuclease activity
MUK71_10965	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MUK71_10980	COG0586	Pfam SNARE associated Golgi protein
MUK71_10985	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MUK71_10990	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MUK71_11000	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MUK71_11010	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
MUK71_11020	COG1335	isochorismatase
MUK71_11040	COG1131	(ABC) transporter
MUK71_11045	COG1902	pentaerythritol trinitrate reductase activity
MUK71_11070	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
MUK71_11085	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MUK71_11095	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MUK71_11100	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MUK71_11105	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MUK71_11110	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MUK71_11115	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MUK71_11120	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MUK71_11125	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MUK71_11130	COG0356	it plays a direct role in the translocation of protons across the membrane
MUK71_11150	COG1086	Polysaccharide biosynthesis protein
MUK71_11165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MUK71_11175	COG2890	protein-(glutamine-N5) methyltransferase activity
MUK71_11180	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MUK71_11190	COG0083	homoserine kinase activity
MUK71_11195	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MUK71_11200	COG0460	homoserine dehydrogenase
MUK71_11205	COG0019	diaminopimelate decarboxylase activity
MUK71_11210	COG0018	arginyl-trna synthetase
MUK71_11240	COG0577	efflux transmembrane transporter activity
MUK71_11240	COG1136	(ABC) transporter
MUK71_11245	COG1136	(ABC) transporter
MUK71_11280	COG0559	Belongs to the binding-protein-dependent transport system permease family
MUK71_11310	COG1643	Atp-dependent helicase
MUK71_11315	COG0537	adenosine 5'-monophosphoramidase activity
MUK71_11325	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MUK71_11340	COG1121	(ABC) transporter
MUK71_11355	COG1253	flavin adenine dinucleotide binding
MUK71_11360	COG0508	dehydrogenase complex catalyzes the overall conversion of
MUK71_11360	COG0567	Dehydrogenase, E1 component
MUK71_11370	COG0747	negative chemotaxis
MUK71_11380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MUK71_11390	COG0604	alcohol dehydrogenase
MUK71_11400	COG1595	DNA-templated transcription, initiation
MUK71_11410	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MUK71_11420	COG0483	inositol monophosphate 1-phosphatase activity
MUK71_11430	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
MUK71_11435	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
MUK71_11440	COG0366	Alpha amylase catalytic
MUK71_11470	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MUK71_11475	COG0739	heme binding
MUK71_11475	COG0741	lytic transglycosylase activity
MUK71_11475	COG1196	nuclear chromosome segregation
MUK71_11480	COG2177	Part of the ABC transporter FtsEX involved in
MUK71_11485	COG2884	Cell division ATP-binding protein ftsE
MUK71_11490	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MUK71_11500	COG1215	transferase activity, transferring glycosyl groups
MUK71_11560	COG1215	transferase activity, transferring glycosyl groups
MUK71_11575	COG1088	dTDP-glucose 4,6-dehydratase activity
MUK71_11585	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MUK71_11600	COG2801	Transposase and inactivated derivatives
MUK71_11615	COG1216	Glycosyl transferase, family 2
MUK71_11630	COG1674	ftsk spoiiie
MUK71_11650	COG2902	Dehydrogenase
MUK71_11685	COG0653	protein targeting
MUK71_11690	COG3214	Protein conserved in bacteria
MUK71_11695	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MUK71_11705	COG5401	PFAM Sporulation and spore germination
MUK71_11710	COG5002	protein histidine kinase activity
MUK71_11715	COG0745	RESPONSE REGULATOR receiver
MUK71_11735	COG0714	Associated with various cellular activities
MUK71_11760	COG0482	sulfurtransferase activity
MUK71_11770	COG0484	heat shock protein binding
MUK71_11775	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MUK71_11785	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MUK71_11790	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
MUK71_11800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MUK71_11815	COG1842	Phage shock protein A
MUK71_11830	COG1615	UPF0182 protein
MUK71_11835	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MUK71_11875	COG1131	(ABC) transporter
MUK71_11885	COG0210	DNA helicase
MUK71_11910	COG2011	ABC-type metal ion transport system permease component
MUK71_11915	COG1464	Belongs to the NlpA lipoprotein family
MUK71_11920	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MUK71_11925	COG0113	porphobilinogen synthase activity
MUK71_11935	COG0181	hydroxymethylbilane synthase activity
MUK71_11940	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MUK71_11945	COG3253	May function as heme-dependent peroxidase
MUK71_11955	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MUK71_11960	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MUK71_12005	COG0613	PHP domain protein
MUK71_12010	COG0006	proline dipeptidase activity
MUK71_12020	COG2239	Acts as a magnesium transporter
MUK71_12035	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MUK71_12045	COG1595	DNA-templated transcription, initiation
MUK71_12055	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MUK71_12070	COG0519	Catalyzes the synthesis of GMP from XMP
MUK71_12085	COG1126	abc transporter atp-binding protein
MUK71_12090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MUK71_12095	COG0765	amino acid transport
MUK71_12100	COG0765	amino acid transport
MUK71_12105	COG2801	Transposase and inactivated derivatives
MUK71_12115	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MUK71_12120	COG2171	N-acyltransferase activity
MUK71_12130	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MUK71_12160	COG1217	gtp-binding protein TYPA
MUK71_12170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MUK71_12175	COG0601	transmembrane transport
MUK71_12205	COG2814	Major facilitator Superfamily
MUK71_12230	COG0012	GTP binding
MUK71_12235	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MUK71_12245	COG1570	exodeoxyribonuclease VII activity
MUK71_12250	COG1722	exodeoxyribonuclease VII activity
MUK71_12265	COG1174	glycine betaine transport
MUK71_12280	COG1051	belongs to the nudix hydrolase family
MUK71_12285	COG2971	BadF BadG BcrA BcrD
MUK71_12310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MUK71_12315	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MUK71_12320	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MUK71_12345	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MUK71_12345	COG0519	Catalyzes the synthesis of GMP from XMP
MUK71_12365	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MUK71_12370	COG0516	GMP reductase activity
MUK71_12385	COG0459	protein refolding
MUK71_12390	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MUK71_12395	COG4607	ABC-type enterochelin transport system periplasmic component
MUK71_12400	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MUK71_12405	COG4605	iron ion homeostasis
MUK71_12410	COG4604	ABC transporter, ATP-binding protein
MUK71_12420	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
MUK71_12430	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MUK71_12435	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
MUK71_12440	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MUK71_12455	COG0802	atpase or kinase
MUK71_12460	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MUK71_12470	COG0667	Aldo Keto reductase
MUK71_12475	COG2721	sulfolactate sulfo-lyase activity
MUK71_12480	COG4948	Mandelate Racemase Muconate Lactonizing
MUK71_12485	COG1904	glucuronate isomerase
MUK71_12490	COG1609	Transcriptional regulator
MUK71_12500	COG3842	ATPase activity
MUK71_12510	COG0395	ABC-type sugar transport system, permease component
MUK71_12515	COG0246	Mannitol dehydrogenase
MUK71_12550	COG0736	holo-[acyl-carrier-protein] synthase activity
MUK71_12560	COG1072	(Pantothenic acid kinase))
MUK71_12565	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MUK71_12570	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MUK71_12575	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MUK71_12580	COG0101	tRNA pseudouridine synthase activity
MUK71_12585	COG0203	ribosomal protein L17
MUK71_12590	COG0202	RNA polymerase activity
MUK71_12595	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MUK71_12600	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MUK71_12605	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MUK71_12610	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MUK71_12615	COG0024	Methionine aminopeptidase
MUK71_12620	COG0563	adenylate kinase activity
MUK71_12630	COG0200	Binds to the 23S rRNA
MUK71_12635	COG1841	ribosomal large subunit assembly
MUK71_12640	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MUK71_12650	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MUK71_12655	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MUK71_12660	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MUK71_12665	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MUK71_12670	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MUK71_12675	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MUK71_12685	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MUK71_12690	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MUK71_12695	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MUK71_12700	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MUK71_12705	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MUK71_12710	COG0089	rRNA binding
MUK71_12715	COG0088	Forms part of the polypeptide exit tunnel
MUK71_12720	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MUK71_12725	COG0051	transcription antitermination factor activity, RNA binding
MUK71_12735	COG0318	PFAM AMP-dependent synthetase and ligase
MUK71_12745	COG0446	pyridine nucleotide-disulphide oxidoreductase
MUK71_12745	COG1902	pentaerythritol trinitrate reductase activity
MUK71_12750	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MUK71_12755	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MUK71_12760	COG0049	tRNA binding
MUK71_12765	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MUK71_12770	COG1414	Transcriptional regulator
MUK71_12775	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MUK71_12785	COG0183	Belongs to the thiolase family
MUK71_12790	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MUK71_12805	COG3485	protocatechuate 3,4-dioxygenase
MUK71_12810	COG3485	protocatechuate 3,4-dioxygenase
MUK71_12825	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MUK71_12830	COG0085	RNA polymerase activity
MUK71_12835	COG0183	Belongs to the thiolase family
MUK71_12840	COG0222	ribosome binding
MUK71_12845	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MUK71_12860	COG0081	regulation of translation
MUK71_12865	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MUK71_12870	COG0250	Participates in transcription elongation, termination and antitermination
MUK71_12875	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MUK71_12885	COG0436	Aminotransferase
MUK71_12890	COG2197	response regulator
MUK71_12930	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MUK71_12935	COG3485	protocatechuate 3,4-dioxygenase
MUK71_12945	COG0745	RESPONSE REGULATOR receiver
MUK71_12950	COG0456	acetyltransferase
MUK71_12955	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MUK71_12970	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MUK71_12975	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MUK71_12980	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MUK71_12985	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MUK71_12995	COG2030	dehydratase
MUK71_13010	COG0693	protein deglycase activity
MUK71_13030	COG2815	serine threonine protein kinase
MUK71_13030	COG0515	serine threonine protein kinase
MUK71_13045	COG5650	phosphatidylinositol metabolic process
MUK71_13050	COG0402	S-adenosylhomocysteine deaminase activity
MUK71_13075	COG0318	PFAM AMP-dependent synthetase and ligase
MUK71_13085	COG0004	ammonium transporteR
MUK71_13090	COG1063	alcohol dehydrogenase
MUK71_13095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MUK71_13115	COG1666	GTP binding
MUK71_13125	COG0501	Belongs to the peptidase M48B family
MUK71_13135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MUK71_13185	COG0142	geranyltranstransferase activity
MUK71_13190	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
MUK71_13195	COG0463	Glycosyl transferase, family 2
MUK71_13295	COG0537	adenosine 5'-monophosphoramidase activity
MUK71_13305	COG0142	geranyltranstransferase activity
MUK71_13310	COG0644	oxidoreductase
MUK71_13315	COG2226	methyltransferase
MUK71_13330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MUK71_13335	COG0765	amino acid transport
MUK71_13345	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MUK71_13355	COG0402	S-adenosylhomocysteine deaminase activity
MUK71_13365	COG4948	Mandelate Racemase Muconate Lactonizing
MUK71_13385	COG0508	dehydrogenase complex catalyzes the overall conversion of
MUK71_13400	COG1522	sequence-specific DNA binding
MUK71_13405	COG2837	iron assimilation
MUK71_13425	COG1028	Short-chain dehydrogenase reductase Sdr
MUK71_13440	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MUK71_13445	COG2151	metal-sulfur cluster biosynthetic enzyme
MUK71_13450	COG3396	Phenylacetate-CoA oxygenase
MUK71_13455	COG3460	Phenylacetate-CoA oxygenase
MUK71_13460	COG3396	Phenylacetate-CoA oxygenase
MUK71_13490	COG2723	6-phospho-beta-galactosidase activity
MUK71_13495	COG0395	ABC-type sugar transport system, permease component
MUK71_13525	COG1012	belongs to the aldehyde dehydrogenase family
MUK71_13525	COG2030	dehydratase
MUK71_13545	COG1793	dna ligase
MUK71_13555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUK71_13585	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MUK71_13610	COG1140	nitrate reductase beta subunit
MUK71_13620	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MUK71_13645	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MUK71_13655	COG0785	Cytochrome C biogenesis protein
MUK71_13660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MUK71_13665	COG0406	alpha-ribazole phosphatase activity
MUK71_13670	COG2353	YceI-like domain
MUK71_13685	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MUK71_13710	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MUK71_13715	COG0640	Transcriptional regulator
MUK71_13720	COG0123	including yeast histone deacetylase and acetoin utilization protein
MUK71_13725	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MUK71_13730	COG0569	domain protein
MUK71_13735	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MUK71_13740	COG1082	Xylose isomerase domain protein TIM barrel
MUK71_13745	COG0248	Ppx GppA phosphatase
MUK71_13750	COG1754	DNA topoisomerase type I activity
MUK71_13750	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MUK71_13755	COG2890	protein-(glutamine-N5) methyltransferase activity
MUK71_13760	COG1053	succinate dehydrogenase
MUK71_13765	COG1054	Belongs to the UPF0176 family
MUK71_13775	COG1111	helicase
MUK71_13775	COG1205	dead DEAH box helicase
MUK71_13815	COG2072	flavoprotein involved in K transport
MUK71_13825	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MUK71_13825	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MUK71_13830	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MUK71_13830	COG2755	lipolytic protein G-D-S-L family
MUK71_13840	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MUK71_13850	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MUK71_13855	COG1764	response to oxidative stress
MUK71_13865	COG0477	Major facilitator Superfamily
MUK71_13905	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MUK71_13910	COG1408	metallophosphoesterase
MUK71_13920	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MUK71_13925	COG0151	Belongs to the GarS family
MUK71_13950	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MUK71_13975	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MUK71_13980	COG1012	belongs to the aldehyde dehydrogenase family
MUK71_13990	COG0768	penicillin binding
MUK71_14010	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MUK71_14015	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
MUK71_14040	COG0789	Transcriptional regulator
MUK71_14045	COG0484	heat shock protein binding
MUK71_14050	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MUK71_14055	COG0443	Heat shock 70 kDa protein
MUK71_14065	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MUK71_14075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MUK71_14090	COG1122	ATPase activity
MUK71_14095	COG4721	ABC-type cobalt transport system, permease component
MUK71_14110	COG2212	antiporter activity
MUK71_14120	COG0651	ATP synthesis coupled electron transport
MUK71_14125	COG1006	Multisubunit Na H antiporter MnhC subunit
MUK71_14130	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MUK71_14130	COG2111	Na H antiporter
MUK71_14140	COG0717	Belongs to the dCTP deaminase family
MUK71_14145	COG3483	tryptophan 2,3-dioxygenase activity
MUK71_14170	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MUK71_14210	COG3336	cytochrome c oxidase
MUK71_14215	COG0776	regulation of translation
MUK71_14225	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MUK71_14230	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MUK71_14235	COG0227	Belongs to the bacterial ribosomal protein bL28 family
MUK71_14240	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MUK71_14250	COG0477	Major facilitator Superfamily
MUK71_14260	COG1597	lipid kinase activity
MUK71_14265	COG0739	heme binding
MUK71_14265	COG0741	lytic transglycosylase activity
MUK71_14265	COG1196	nuclear chromosome segregation
MUK71_14270	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MUK71_14275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MUK71_14290	COG1120	ATPase activity
MUK71_14295	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MUK71_14300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MUK71_14305	COG0435	Glutathione S-transferase
MUK71_14315	COG0492	ferredoxin-NADP+ reductase activity
MUK71_14320	COG0531	amino acid
MUK71_14325	COG1295	ribonuclease BN
MUK71_14345	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MUK71_14350	COG2146	nitrite reductase [NAD(P)H] activity
MUK71_14375	COG1028	Short-chain dehydrogenase reductase Sdr
MUK71_14380	COG1960	acyl-CoA dehydrogenase activity
MUK71_14390	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
MUK71_14410	COG1414	Transcriptional regulator
MUK71_14435	COG1732	Glycine betaine
MUK71_14440	COG1174	glycine betaine transport
MUK71_14450	COG1174	glycine betaine transport
MUK71_14480	COG4585	Histidine kinase
MUK71_14485	COG2197	response regulator
MUK71_14490	COG4152	abc transporter atp-binding protein
MUK71_14520	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MUK71_14525	COG1012	belongs to the aldehyde dehydrogenase family
MUK71_14545	COG0318	PFAM AMP-dependent synthetase and ligase
MUK71_14555	COG4221	oxidoreductase activity
MUK71_14565	COG2755	lipolytic protein G-D-S-L family
MUK71_14580	COG0028	Belongs to the TPP enzyme family
MUK71_14590	COG0596	Alpha beta hydrolase
MUK71_14595	COG5002	protein histidine kinase activity
MUK71_14605	COG1012	belongs to the aldehyde dehydrogenase family
MUK71_14610	COG2860	membrane
MUK71_14620	COG1063	alcohol dehydrogenase
MUK71_14640	COG1072	(Pantothenic acid kinase))
MUK71_14645	COG3386	PFAM SMP-30 Gluconolaconase
MUK71_14655	COG2508	Transcriptional regulator
MUK71_14660	COG1929	Belongs to the glycerate kinase type-1 family
MUK71_14665	COG2610	gluconate transmembrane transporter activity
MUK71_14670	COG0531	amino acid
MUK71_14700	COG0492	ferredoxin-NADP+ reductase activity
MUK71_14745	COG1028	Short-chain dehydrogenase reductase Sdr
MUK71_14780	COG2217	Heavy metal translocating P-type atpase
MUK71_14785	COG0471	metal ion transport
MUK71_14785	COG0490	domain, Protein
MUK71_14790	COG0598	Magnesium transport protein CorA
MUK71_14815	COG3546	catalase activity
MUK71_14840	COG1028	Short-chain dehydrogenase reductase Sdr
MUK71_14845	COG2814	Major facilitator Superfamily
MUK71_14855	COG0477	Major facilitator Superfamily
MUK71_14865	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MUK71_14875	COG2301	Belongs to the HpcH HpaI aldolase family
MUK71_14880	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MUK71_14885	COG3622	Belongs to the hyi family
MUK71_14890	COG3257	ureidoglycine aminohydrolase activity
MUK71_14900	COG2233	PERMEase
MUK71_14935	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MUK71_14940	COG0697	spore germination
MUK71_14945	COG1846	Transcriptional regulator
MUK71_14980	COG5650	phosphatidylinositol metabolic process
MUK71_14990	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MUK71_15015	COG1129	ABC transporter
MUK71_15020	COG1172	Belongs to the binding-protein-dependent transport system permease family
MUK71_15025	COG1735	metal-dependent hydrolase with the TIM-barrel fold
MUK71_15050	COG3971	2-oxopent-4-enoate hydratase activity
MUK71_15060	COG1012	belongs to the aldehyde dehydrogenase family
MUK71_15075	COG1196	nuclear chromosome segregation
MUK71_15080	COG1902	pentaerythritol trinitrate reductase activity
MUK71_15145	COG0656	L-ascorbic acid biosynthetic process
MUK71_15165	COG2076	Multidrug Resistance protein
MUK71_15220	COG1742	UPF0060 membrane protein
MUK71_15225	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MUK71_15250	COG0656	L-ascorbic acid biosynthetic process
MUK71_15275	COG2197	response regulator
MUK71_15315	COG1937	Protein conserved in bacteria
MUK71_15320	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MUK71_15350	COG1132	(ABC) transporter
MUK71_15365	COG2409	Drug exporters of the RND superfamily
MUK71_15380	COG0667	Aldo Keto reductase
MUK71_15390	COG0277	FAD linked oxidase domain protein
MUK71_15395	COG1620	l-lactate permease
MUK71_15400	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MUK71_15405	COG1028	Short-chain dehydrogenase reductase Sdr
MUK71_15415	COG1115	amino acid carrier protein
MUK71_15425	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MUK71_15430	COG0509	glycine decarboxylation via glycine cleavage system
MUK71_15435	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MUK71_15440	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MUK71_15440	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MUK71_15445	COG1113	amino acid transport
MUK71_15470	COG1302	Protein conserved in bacteria
MUK71_15480	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MUK71_15500	COG0686	Belongs to the AlaDH PNT family
MUK71_15535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MUK71_15540	COG0508	dehydrogenase complex catalyzes the overall conversion of
MUK71_15545	COG0022	dehydrogenase e1 component
MUK71_15555	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MUK71_15560	COG1950	PFAM Membrane protein of
MUK71_15575	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MUK71_15580	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MUK71_15590	COG0590	tRNA wobble adenosine to inosine editing
MUK71_15595	COG0789	Transcriptional regulator
MUK71_15615	COG2080	2 iron, 2 sulfur cluster binding
MUK71_15620	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
MUK71_15625	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MUK71_15670	COG1309	transcriptional regulator
MUK71_15675	COG1329	Transcriptional regulator
MUK71_15700	COG1063	alcohol dehydrogenase
MUK71_15720	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MUK71_15735	COG3145	DNA-N1-methyladenine dioxygenase activity
MUK71_15740	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MUK71_15745	COG1595	DNA-templated transcription, initiation
MUK71_15750	COG0318	PFAM AMP-dependent synthetase and ligase
MUK71_15775	COG3655	Transcriptional regulator
MUK71_15795	COG1940	carbohydrate kinase activity
MUK71_15805	COG2205	protein histidine kinase activity
MUK71_15810	COG0745	RESPONSE REGULATOR receiver
MUK71_15825	COG0477	Major facilitator Superfamily
MUK71_15835	COG1028	Short-chain dehydrogenase reductase Sdr
MUK71_15845	COG1960	acyl-CoA dehydrogenase activity
MUK71_15860	COG1028	Short-chain dehydrogenase reductase Sdr
MUK71_15880	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MUK71_15895	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MUK71_15910	COG0534	Mate efflux family protein
MUK71_15915	COG2814	Major facilitator Superfamily
MUK71_15940	COG4214	carbohydrate transport
MUK71_15950	COG4213	ABC transporter substrate-binding protein
MUK71_15955	COG2160	L-arabinose isomerase activity
MUK71_15970	COG1609	Transcriptional regulator
MUK71_15975	COG0531	amino acid
MUK71_15985	COG0305	Participates in initiation and elongation during chromosome replication
MUK71_15990	COG0359	binds to the 23S rRNA
MUK71_15995	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MUK71_16005	COG0360	Binds together with S18 to 16S ribosomal RNA
MUK71_16010	COG1362	aminopeptidase activity
MUK71_16020	COG1131	(ABC) transporter
MUK71_16025	COG1131	(ABC) transporter
MUK71_16040	COG0738	Major facilitator superfamily
MUK71_16045	COG0488	(ABC) transporter
MUK71_16090	COG2759	Belongs to the formate--tetrahydrofolate ligase family
MUK71_16095	COG0438	transferase activity, transferring glycosyl groups
MUK71_16105	COG0406	alpha-ribazole phosphatase activity
MUK71_16110	COG0617	tRNA 3'-terminal CCA addition
MUK71_16130	COG0492	ferredoxin-NADP+ reductase activity
MUK71_16135	COG3118	belongs to the thioredoxin family
MUK71_16140	COG0860	N-Acetylmuramoyl-L-alanine amidase
MUK71_16140	COG3409	Peptidoglycan-binding domain 1 protein
MUK71_16145	COG0583	DNA-binding transcription factor activity
MUK71_16170	COG1475	DNA binding
MUK71_16175	COG1192	Involved in chromosome partitioning
MUK71_16180	COG0357	Ribosomal RNA small subunit methyltransferase G
MUK71_16185	COG1847	R3H domain protein
MUK71_16190	COG0706	membrane insertase activity
MUK71_16200	COG0594	ribonuclease P activity
MUK71_16205	COG0230	Belongs to the bacterial ribosomal protein bL34 family