locus-tag	class	description
MNQ99_00010	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MNQ99_00020	COG1435	thymidine kinase activity
MNQ99_00030	COG0640	Transcriptional regulator
MNQ99_00035	COG0346	lactoylglutathione lyase activity
MNQ99_00080	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MNQ99_00095	COG1940	carbohydrate kinase activity
MNQ99_00100	COG1129	ABC transporter
MNQ99_00105	COG1172	Belongs to the binding-protein-dependent transport system permease family
MNQ99_00110	COG4214	carbohydrate transport
MNQ99_00125	COG0673	inositol 2-dehydrogenase activity
MNQ99_00135	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MNQ99_00160	COG1609	Transcriptional regulator
MNQ99_00165	COG0395	ABC-type sugar transport system, permease component
MNQ99_00170	COG1175	transmembrane transport
MNQ99_00175	COG1653	transport
MNQ99_00180	COG0366	Alpha amylase catalytic
MNQ99_00250	COG0791	NLP P60 protein
MNQ99_00250	COG3883	PFAM NLP P60 protein
MNQ99_00265	COG2252	PERMEase
MNQ99_00275	COG0583	DNA-binding transcription factor activity
MNQ99_00285	COG4122	O-methyltransferase activity
MNQ99_00295	COG1064	alcohol dehydrogenase
MNQ99_00310	COG3387	PFAM Glycoside hydrolase 15-related
MNQ99_00310	COG3387	PFAM Glycoside hydrolase 15-related
MNQ99_00320	COG2733	membrane
MNQ99_00325	COG1984	allophanate hydrolase subunit 2
MNQ99_00330	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MNQ99_00335	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
MNQ99_00365	COG1012	belongs to the aldehyde dehydrogenase family
MNQ99_00380	COG0247	lactate metabolic process
MNQ99_00380	COG0277	FAD linked oxidase domain protein
MNQ99_00385	COG0577	efflux transmembrane transporter activity
MNQ99_00385	COG1136	(ABC) transporter
MNQ99_00395	COG5285	phytanoyl-CoA dioxygenase
MNQ99_00400	COG1917	Cupin 2, conserved barrel domain protein
MNQ99_00410	COG0456	acetyltransferase
MNQ99_00435	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MNQ99_00465	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MNQ99_00480	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MNQ99_00485	COG0823	Involved in the tonB-independent uptake of proteins
MNQ99_00485	COG1506	peptidase
MNQ99_00485	COG4946	Tricorn protease homolog
MNQ99_00505	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MNQ99_00510	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MNQ99_00535	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MNQ99_00540	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MNQ99_00550	COG0302	gtp cyclohydrolase
MNQ99_00555	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MNQ99_00565	COG0037	tRNA processing
MNQ99_00575	COG2027	D-alanyl-D-alanine carboxypeptidase
MNQ99_00600	COG0561	phosphatase activity
MNQ99_00605	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MNQ99_00615	COG3415	Transposase
MNQ99_00615	COG2801	Transposase and inactivated derivatives
MNQ99_00625	COG0077	Prephenate dehydratase
MNQ99_00630	COG1054	Belongs to the UPF0176 family
MNQ99_00635	COG3340	Belongs to the peptidase S51 family
MNQ99_00640	COG0154	amidase activity
MNQ99_00645	COG3104	oligopeptide transport
MNQ99_00660	COG2233	PERMEase
MNQ99_00665	COG3360	Dodecin
MNQ99_00690	COG0659	secondary active sulfate transmembrane transporter activity
MNQ99_00700	COG1929	Belongs to the glycerate kinase type-1 family
MNQ99_00705	COG0584	glycerophosphoryl diester phosphodiesterase
MNQ99_00715	COG0561	phosphatase activity
MNQ99_00720	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MNQ99_00730	COG1609	Transcriptional regulator
MNQ99_00735	COG1793	dna ligase
MNQ99_00735	COG3285	dna ligase
MNQ99_00740	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MNQ99_00755	COG2814	Major facilitator Superfamily
MNQ99_00760	COG2814	Major facilitator Superfamily
MNQ99_00765	COG1309	transcriptional regulator
MNQ99_00795	COG1024	Enoyl-CoA hydratase
MNQ99_00800	COG0483	inositol monophosphate 1-phosphatase activity
MNQ99_00820	COG2197	response regulator
MNQ99_00845	COG1716	ATPase activity
MNQ99_00850	COG1716	ATPase activity
MNQ99_00870	COG0515	serine threonine protein kinase
MNQ99_00875	COG2815	serine threonine protein kinase
MNQ99_00875	COG0515	serine threonine protein kinase
MNQ99_00890	COG0598	Magnesium transport protein CorA
MNQ99_00900	COG0705	Rhomboid family
MNQ99_00915	COG1215	transferase activity, transferring glycosyl groups
MNQ99_00940	COG3266	domain, Protein
MNQ99_00945	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MNQ99_00950	COG0187	DNA topoisomerase II activity
MNQ99_00955	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
MNQ99_00960	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MNQ99_00965	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
MNQ99_00970	COG0592	DNA-directed DNA polymerase activity
MNQ99_00975	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MNQ99_00980	COG0230	Belongs to the bacterial ribosomal protein bL34 family
MNQ99_00985	COG0594	ribonuclease P activity
MNQ99_00990	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MNQ99_00995	COG0706	membrane insertase activity
MNQ99_01005	COG0357	Ribosomal RNA small subunit methyltransferase G
MNQ99_01010	COG1192	Involved in chromosome partitioning
MNQ99_01015	COG1475	DNA binding
MNQ99_01025	COG0860	N-Acetylmuramoyl-L-alanine amidase
MNQ99_01025	COG3409	Peptidoglycan-binding domain 1 protein
MNQ99_01030	COG3118	belongs to the thioredoxin family
MNQ99_01035	COG0492	ferredoxin-NADP+ reductase activity
MNQ99_01055	COG0617	tRNA 3'-terminal CCA addition
MNQ99_01060	COG0588	phosphoglycerate mutase activity
MNQ99_01070	COG2261	transglycosylase associated protein
MNQ99_01075	COG2759	Belongs to the formate--tetrahydrofolate ligase family
MNQ99_01105	COG1215	transferase activity, transferring glycosyl groups
MNQ99_01110	COG2089	acid synthase
MNQ99_01130	COG1796	DNA polymerase
MNQ99_01130	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MNQ99_01135	COG1403	HNH endonuclease
MNQ99_01140	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MNQ99_01145	COG0577	efflux transmembrane transporter activity
MNQ99_01145	COG1136	(ABC) transporter
MNQ99_01165	COG2197	response regulator
MNQ99_01170	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
MNQ99_01175	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MNQ99_01180	COG0488	(ABC) transporter
MNQ99_01185	COG0738	Major facilitator superfamily
MNQ99_01215	COG4585	Histidine kinase
MNQ99_01220	COG2197	response regulator
MNQ99_01225	COG0360	Binds together with S18 to 16S ribosomal RNA
MNQ99_01235	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MNQ99_01240	COG0359	binds to the 23S rRNA
MNQ99_01245	COG0384	phenazine biosynthesis protein PhzF
MNQ99_01260	COG0305	Participates in initiation and elongation during chromosome replication
MNQ99_01265	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MNQ99_01280	COG0300	oxidoreductase activity
MNQ99_01290	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MNQ99_01295	COG1122	ATPase activity
MNQ99_01300	COG4721	ABC-type cobalt transport system, permease component
MNQ99_01340	COG0318	PFAM AMP-dependent synthetase and ligase
MNQ99_01350	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MNQ99_01360	COG2318	DinB family
MNQ99_01370	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MNQ99_01410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MNQ99_01415	COG1116	anion transmembrane transporter activity
MNQ99_01415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MNQ99_01425	COG0667	Aldo Keto reductase
MNQ99_01450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MNQ99_01460	COG0411	ABC transporter
MNQ99_01475	COG1012	belongs to the aldehyde dehydrogenase family
MNQ99_01490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MNQ99_01495	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
MNQ99_01510	COG3962	Belongs to the TPP enzyme family
MNQ99_01515	COG0477	Major facilitator Superfamily
MNQ99_01555	COG0477	Major facilitator Superfamily
MNQ99_01560	COG0693	protein deglycase activity
MNQ99_01570	COG0154	amidase activity
MNQ99_01580	COG1086	Polysaccharide biosynthesis protein
MNQ99_01590	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MNQ99_01605	COG3268	Saccharopine dehydrogenase
MNQ99_01650	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MNQ99_01660	COG3257	ureidoglycine aminohydrolase activity
MNQ99_01665	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MNQ99_01670	COG2814	Major facilitator Superfamily
MNQ99_01685	COG0534	Mate efflux family protein
MNQ99_01710	COG0697	spore germination
MNQ99_01715	COG0574	Belongs to the PEP-utilizing enzyme family
MNQ99_01715	COG3848	Pyruvate phosphate dikinase
MNQ99_01725	COG2814	Major facilitator Superfamily
MNQ99_01740	COG3620	sequence-specific DNA binding
MNQ99_01755	COG1937	Protein conserved in bacteria
MNQ99_01760	COG0477	Major facilitator Superfamily
MNQ99_01805	COG0492	ferredoxin-NADP+ reductase activity
MNQ99_01815	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MNQ99_01835	COG0436	Aminotransferase
MNQ99_01845	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MNQ99_01855	COG0667	Aldo Keto reductase
MNQ99_01870	COG1607	acyl-coa hydrolase
MNQ99_01875	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MNQ99_01885	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MNQ99_01900	COG1950	PFAM Membrane protein of
MNQ99_01905	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MNQ99_01915	COG0022	dehydrogenase e1 component
MNQ99_01920	COG0508	dehydrogenase complex catalyzes the overall conversion of
MNQ99_01925	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MNQ99_01930	COG0346	lactoylglutathione lyase activity
MNQ99_01940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MNQ99_02000	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MNQ99_02010	COG2211	Major facilitator Superfamily
MNQ99_02015	COG2815	serine threonine protein kinase
MNQ99_02015	COG0515	serine threonine protein kinase
MNQ99_02020	COG3842	ATPase activity
MNQ99_02030	COG0395	ABC-type sugar transport system, permease component
MNQ99_02045	COG1737	Transcriptional regulator
MNQ99_02060	COG0252	asparaginase activity
MNQ99_02065	COG0726	polysaccharide deacetylase
MNQ99_02070	COG0477	Major facilitator Superfamily
MNQ99_02075	COG1028	Short-chain dehydrogenase reductase Sdr
MNQ99_02080	COG1028	Short-chain dehydrogenase reductase Sdr
MNQ99_02090	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MNQ99_02145	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MNQ99_02150	COG0363	glucosamine-6-phosphate deaminase activity
MNQ99_02155	COG4335	DNA alkylation repair
MNQ99_02160	COG0596	Alpha beta hydrolase
MNQ99_02180	COG1278	Cold shock
MNQ99_02230	COG0583	DNA-binding transcription factor activity
MNQ99_02235	COG0531	amino acid
MNQ99_02270	COG0039	L-malate dehydrogenase activity
MNQ99_02275	COG0412	Dienelactone hydrolase
MNQ99_02310	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MNQ99_02345	COG1278	Cold shock
MNQ99_02355	COG0656	L-ascorbic acid biosynthetic process
MNQ99_02360	COG2050	protein possibly involved in aromatic compounds catabolism
MNQ99_02385	COG2910	NAD(P)H-binding
MNQ99_02400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MNQ99_02405	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MNQ99_02410	COG1116	anion transmembrane transporter activity
MNQ99_02420	COG1028	Short-chain dehydrogenase reductase Sdr
MNQ99_02430	COG1960	acyl-CoA dehydrogenase activity
MNQ99_02450	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MNQ99_02485	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MNQ99_02495	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MNQ99_02505	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MNQ99_02520	COG1414	Transcriptional regulator
MNQ99_02530	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MNQ99_02560	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MNQ99_02565	COG1268	BioY protein
MNQ99_02580	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MNQ99_02590	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MNQ99_02600	COG0673	inositol 2-dehydrogenase activity
MNQ99_02605	COG2860	membrane
MNQ99_02610	COG4565	transcriptional regulatory protein
MNQ99_02615	COG3290	protein histidine kinase activity
MNQ99_02620	COG2851	Citrate transporter
MNQ99_02640	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MNQ99_02645	COG1802	Transcriptional regulator
MNQ99_02650	COG0747	negative chemotaxis
MNQ99_02660	COG4948	Mandelate Racemase Muconate Lactonizing
MNQ99_02670	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MNQ99_02675	COG0583	DNA-binding transcription factor activity
MNQ99_02695	COG0589	response to stress
MNQ99_02700	COG1609	Transcriptional regulator
MNQ99_02710	COG1414	Transcriptional regulator
MNQ99_02715	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MNQ99_02720	COG0747	negative chemotaxis
MNQ99_02730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MNQ99_02735	COG0444	Belongs to the ABC transporter superfamily
MNQ99_02740	COG4608	Belongs to the ABC transporter superfamily
MNQ99_02750	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MNQ99_02755	COG4948	Mandelate Racemase Muconate Lactonizing
MNQ99_02760	COG0583	DNA-binding transcription factor activity
MNQ99_02770	COG0443	Heat shock 70 kDa protein
MNQ99_02825	COG2353	YceI-like domain
MNQ99_02830	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MNQ99_02835	COG1846	Transcriptional regulator
MNQ99_02835	COG1940	carbohydrate kinase activity
MNQ99_02840	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MNQ99_02860	COG3971	2-oxopent-4-enoate hydratase activity
MNQ99_02875	COG2124	cytochrome p450
MNQ99_02955	COG3433	isochorismatase activity
MNQ99_02955	COG1535	isochorismatase
MNQ99_02970	COG1643	Atp-dependent helicase
MNQ99_02975	COG1960	acyl-CoA dehydrogenase activity
MNQ99_03020	COG1024	Enoyl-CoA hydratase
MNQ99_03040	COG0640	Transcriptional regulator
MNQ99_03050	COG0471	metal ion transport
MNQ99_03055	COG0583	DNA-binding transcription factor activity
MNQ99_03060	COG4948	Mandelate Racemase Muconate Lactonizing
MNQ99_03065	COG4829	muconolactone delta-isomerase
MNQ99_03070	COG3485	protocatechuate 3,4-dioxygenase
MNQ99_03085	COG1063	alcohol dehydrogenase
MNQ99_03095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MNQ99_03100	COG1793	dna ligase
MNQ99_03110	COG1414	Transcriptional regulator
MNQ99_03120	COG2124	cytochrome p450
MNQ99_03135	COG1012	belongs to the aldehyde dehydrogenase family
MNQ99_03150	COG0584	glycerophosphoryl diester phosphodiesterase
MNQ99_03180	COG0667	Aldo Keto reductase
MNQ99_03190	COG4989	oxidoreductase activity
MNQ99_03230	COG1126	abc transporter atp-binding protein
MNQ99_03235	COG0765	amino acid transport
MNQ99_03240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MNQ99_03245	COG1803	Methylglyoxal synthase
MNQ99_03245	COG1597	lipid kinase activity
MNQ99_03250	COG0768	penicillin binding
MNQ99_03265	COG1254	Belongs to the acylphosphatase family
MNQ99_03295	COG0436	Aminotransferase
MNQ99_03305	COG1902	pentaerythritol trinitrate reductase activity
MNQ99_03310	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MNQ99_03320	COG1191	sigma factor activity
MNQ99_03335	COG0859	PFAM glycosyl transferase family 9
MNQ99_03345	COG0438	transferase activity, transferring glycosyl groups
MNQ99_03350	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
MNQ99_03355	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
MNQ99_03355	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MNQ99_03375	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
MNQ99_03375	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MNQ99_03420	COG1937	Protein conserved in bacteria
MNQ99_03425	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MNQ99_03430	COG0730	response to heat
MNQ99_03435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MNQ99_03455	COG2807	transmembrane transport
MNQ99_03465	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MNQ99_03465	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MNQ99_03470	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MNQ99_03505	COG0589	response to stress
MNQ99_03510	COG0519	Catalyzes the synthesis of GMP from XMP
MNQ99_03520	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MNQ99_03530	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MNQ99_03535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MNQ99_03550	COG2807	transmembrane transport
MNQ99_03555	COG2031	fatty acid transporter
MNQ99_03580	COG0435	Glutathione S-transferase
MNQ99_03585	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
MNQ99_03595	COG0789	Transcriptional regulator
MNQ99_03625	COG2267	carboxylic ester hydrolase activity
MNQ99_03630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MNQ99_03635	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MNQ99_03640	COG1120	ATPase activity
MNQ99_03650	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MNQ99_03660	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MNQ99_03675	COG3842	ATPase activity
MNQ99_03680	COG1176	ABC-type spermidine putrescine transport system, permease component I
MNQ99_03685	COG1177	transmembrane transport
MNQ99_03690	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MNQ99_03695	COG1742	UPF0060 membrane protein
MNQ99_03710	COG0477	Major facilitator Superfamily
MNQ99_03725	COG0227	Belongs to the bacterial ribosomal protein bL28 family
MNQ99_03730	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MNQ99_03735	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MNQ99_03740	COG0776	regulation of translation
MNQ99_03770	COG0433	COG0433 Predicted ATPase
MNQ99_03780	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MNQ99_03825	COG3483	tryptophan 2,3-dioxygenase activity
MNQ99_03830	COG0717	Belongs to the dCTP deaminase family
MNQ99_03840	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MNQ99_03840	COG2111	Na H antiporter
MNQ99_03845	COG1006	Multisubunit Na H antiporter MnhC subunit
MNQ99_03850	COG0651	ATP synthesis coupled electron transport
MNQ99_03860	COG2212	antiporter activity
MNQ99_03865	COG1320	monovalent cation:proton antiporter activity
MNQ99_03875	COG4721	ABC-type cobalt transport system, permease component
MNQ99_03880	COG4172	Belongs to the ABC transporter superfamily
MNQ99_03900	COG0512	Glutamine amidotransferase of anthranilate synthase
MNQ99_03900	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MNQ99_03905	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MNQ99_03910	COG1280	lysine exporter protein (LysE YggA)
MNQ99_03930	COG2409	Drug exporters of the RND superfamily
MNQ99_03935	COG0443	Heat shock 70 kDa protein
MNQ99_03940	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MNQ99_03945	COG0484	heat shock protein binding
MNQ99_03950	COG0789	Transcriptional regulator
MNQ99_03955	COG2003	Belongs to the UPF0758 family
MNQ99_03975	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MNQ99_03995	COG2353	YceI-like domain
MNQ99_04030	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MNQ99_04055	COG0151	Belongs to the GarS family
MNQ99_04060	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MNQ99_04080	COG1132	(ABC) transporter
MNQ99_04085	COG1132	(ABC) transporter
MNQ99_04100	COG1408	metallophosphoesterase
MNQ99_04105	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
MNQ99_04135	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MNQ99_04140	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MNQ99_04150	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MNQ99_04205	COG1205	dead DEAH box helicase
MNQ99_04205	COG1111	helicase
MNQ99_04215	COG1054	Belongs to the UPF0176 family
MNQ99_04230	COG2890	protein-(glutamine-N5) methyltransferase activity
MNQ99_04240	COG1754	DNA topoisomerase type I activity
MNQ99_04240	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MNQ99_04245	COG0248	Ppx GppA phosphatase
MNQ99_04255	COG0569	domain protein
MNQ99_04260	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MNQ99_04265	COG0123	including yeast histone deacetylase and acetoin utilization protein
MNQ99_04270	COG0640	Transcriptional regulator
MNQ99_04275	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MNQ99_04280	COG2971	BadF BadG BcrA BcrD
MNQ99_04285	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MNQ99_04310	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MNQ99_04320	COG0406	alpha-ribazole phosphatase activity
MNQ99_04325	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MNQ99_04330	COG0785	Cytochrome C biogenesis protein
MNQ99_04340	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MNQ99_04370	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MNQ99_04375	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
MNQ99_04400	COG1024	Enoyl-CoA hydratase
MNQ99_04405	COG1250	3-hydroxyacyl-CoA dehydrogenase
MNQ99_04420	COG1012	belongs to the aldehyde dehydrogenase family
MNQ99_04420	COG2030	dehydratase
MNQ99_04465	COG3396	Phenylacetate-CoA oxygenase
MNQ99_04470	COG3460	Phenylacetate-CoA oxygenase
MNQ99_04475	COG3396	Phenylacetate-CoA oxygenase
MNQ99_04480	COG2151	metal-sulfur cluster biosynthetic enzyme
MNQ99_04485	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MNQ99_04490	COG1024	Enoyl-CoA hydratase
MNQ99_04495	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MNQ99_04515	COG0022	dehydrogenase e1 component
MNQ99_04520	COG0508	dehydrogenase complex catalyzes the overall conversion of
MNQ99_04550	COG4948	Mandelate Racemase Muconate Lactonizing
MNQ99_04570	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MNQ99_04580	COG0765	amino acid transport
MNQ99_04585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MNQ99_04590	COG1169	isochorismate synthase
MNQ99_04595	COG2226	methyltransferase
MNQ99_04605	COG0142	geranyltranstransferase activity
MNQ99_04610	COG1280	lysine exporter protein (LysE YggA)
MNQ99_04630	COG0733	neurotransmitter:sodium symporter activity
MNQ99_04655	COG3739	integral membrane protein
MNQ99_04660	COG3655	Transcriptional regulator
MNQ99_04675	COG0577	efflux transmembrane transporter activity
MNQ99_04675	COG1136	(ABC) transporter
MNQ99_04680	COG0577	efflux transmembrane transporter activity
MNQ99_04680	COG1136	(ABC) transporter
MNQ99_04700	COG1674	ftsk spoiiie
MNQ99_04790	COG0753	catalase activity
MNQ99_04805	COG0501	Belongs to the peptidase M48B family
MNQ99_04815	COG2146	nitrite reductase [NAD(P)H] activity
MNQ99_04815	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MNQ99_04820	COG1666	GTP binding
MNQ99_04845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MNQ99_04875	COG0446	pyridine nucleotide-disulphide oxidoreductase
MNQ99_04875	COG1902	pentaerythritol trinitrate reductase activity
MNQ99_04890	COG2890	protein-(glutamine-N5) methyltransferase activity
MNQ99_04915	COG2030	dehydratase
MNQ99_04925	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MNQ99_04940	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MNQ99_04945	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MNQ99_04950	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MNQ99_04970	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MNQ99_04975	COG0456	acetyltransferase
MNQ99_04980	COG0745	RESPONSE REGULATOR receiver
MNQ99_04990	COG3485	protocatechuate 3,4-dioxygenase
MNQ99_04995	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MNQ99_05030	COG2197	response regulator
MNQ99_05040	COG0436	Aminotransferase
MNQ99_05055	COG0250	Participates in transcription elongation, termination and antitermination
MNQ99_05060	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MNQ99_05065	COG0081	regulation of translation
MNQ99_05085	COG1140	nitrate reductase beta subunit
MNQ99_05105	COG2186	Transcriptional regulator
MNQ99_05110	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MNQ99_05115	COG0222	ribosome binding
MNQ99_05120	COG0442	prolyl-tRNA aminoacylation
MNQ99_05125	COG0183	Belongs to the thiolase family
MNQ99_05130	COG0085	RNA polymerase activity
MNQ99_05135	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MNQ99_05150	COG3485	protocatechuate 3,4-dioxygenase
MNQ99_05155	COG3485	protocatechuate 3,4-dioxygenase
MNQ99_05170	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MNQ99_05175	COG0183	Belongs to the thiolase family
MNQ99_05185	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MNQ99_05190	COG1414	Transcriptional regulator
MNQ99_05195	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MNQ99_05200	COG0049	tRNA binding
MNQ99_05205	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MNQ99_05210	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MNQ99_05230	COG0051	transcription antitermination factor activity, RNA binding
MNQ99_05235	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MNQ99_05240	COG0088	Forms part of the polypeptide exit tunnel
MNQ99_05245	COG0089	rRNA binding
MNQ99_05250	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MNQ99_05255	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MNQ99_05260	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MNQ99_05265	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MNQ99_05270	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MNQ99_05275	COG0255	Belongs to the universal ribosomal protein uL29 family
MNQ99_05280	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MNQ99_05285	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MNQ99_05290	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MNQ99_05295	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MNQ99_05300	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MNQ99_05305	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MNQ99_05310	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MNQ99_05315	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MNQ99_05320	COG1841	ribosomal large subunit assembly
MNQ99_05325	COG0200	Binds to the 23S rRNA
MNQ99_05335	COG0563	adenylate kinase activity
MNQ99_05355	COG3191	aminopeptidase activity
MNQ99_05360	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MNQ99_05365	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MNQ99_05370	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MNQ99_05375	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MNQ99_05380	COG0202	RNA polymerase activity
MNQ99_05385	COG0203	ribosomal protein L17
MNQ99_05390	COG0101	tRNA pseudouridine synthase activity
MNQ99_05395	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MNQ99_05400	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MNQ99_05405	COG1256	bacterial-type flagellum assembly
MNQ99_05405	COG4786	Flagellar basal body rod
MNQ99_05415	COG1191	sigma factor activity
MNQ99_05420	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MNQ99_05450	COG1677	Flagellar hook-basal body complex protein FliE
MNQ99_05460	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MNQ99_05470	COG1157	protein secretion by the type III secretion system
MNQ99_05480	COG3883	PFAM NLP P60 protein
MNQ99_05480	COG0791	NLP P60 protein
MNQ99_05490	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
MNQ99_05500	COG1403	HNH endonuclease
MNQ99_05510	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MNQ99_05535	COG1338	Plays a role in the flagellum-specific transport system
MNQ99_05550	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MNQ99_05555	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MNQ99_05565	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MNQ99_05570	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MNQ99_05575	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MNQ99_05580	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MNQ99_05590	COG1970	mechanosensitive ion channel activity
MNQ99_05600	COG1072	(Pantothenic acid kinase))
MNQ99_05605	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MNQ99_05610	COG0736	holo-[acyl-carrier-protein] synthase activity
MNQ99_05630	COG1649	PFAM Uncharacterised BCR, COG1649
MNQ99_05665	COG0667	Aldo Keto reductase
MNQ99_05685	COG0628	permease
MNQ99_05715	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MNQ99_05735	COG1309	transcriptional regulator
MNQ99_05740	COG2409	Drug exporters of the RND superfamily
MNQ99_05760	COG1486	melibiose metabolic process
MNQ99_05765	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MNQ99_05770	COG0802	atpase or kinase
MNQ99_05780	COG0456	acetyltransferase
MNQ99_05780	COG1214	PFAM Peptidase M22, glycoprotease
MNQ99_05790	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MNQ99_05795	COG3979	chitinase
MNQ99_05805	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
MNQ99_05830	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MNQ99_05845	COG4604	ABC transporter, ATP-binding protein
MNQ99_05850	COG4605	iron ion homeostasis
MNQ99_05855	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MNQ99_05860	COG4607	ABC-type enterochelin transport system periplasmic component
MNQ99_05865	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MNQ99_05870	COG0459	protein refolding
MNQ99_05885	COG0516	GMP reductase activity
MNQ99_05890	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MNQ99_05905	COG0519	Catalyzes the synthesis of GMP from XMP
MNQ99_05905	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MNQ99_05925	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MNQ99_05930	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MNQ99_05950	COG0745	RESPONSE REGULATOR receiver
MNQ99_05955	COG5002	protein histidine kinase activity
MNQ99_05985	COG1162	GTPase activity
MNQ99_05995	COG1174	glycine betaine transport
MNQ99_06000	COG4176	ABC-type proline glycine betaine transport system permease component
MNQ99_06010	COG0436	Aminotransferase
MNQ99_06015	COG2326	polyphosphate kinase activity
MNQ99_06020	COG1722	exodeoxyribonuclease VII activity
MNQ99_06025	COG1570	exodeoxyribonuclease VII activity
MNQ99_06035	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MNQ99_06045	COG2801	Transposase and inactivated derivatives
MNQ99_06055	COG0012	GTP binding
MNQ99_06060	COG2824	Alkylphosphonate utilization operon protein PhnA
MNQ99_06070	COG0583	DNA-binding transcription factor activity
MNQ99_06080	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MNQ99_06095	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
MNQ99_06100	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MNQ99_06120	COG2824	Alkylphosphonate utilization operon protein PhnA
MNQ99_06125	COG3591	Belongs to the peptidase S1B family
MNQ99_06125	COG1864	DNA RNA non-specific endonuclease
MNQ99_06140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MNQ99_06145	COG2824	Alkylphosphonate utilization operon protein PhnA
MNQ99_06175	COG0723	plastoquinol--plastocyanin reductase activity
MNQ99_06195	COG0346	lactoylglutathione lyase activity
MNQ99_06205	COG1309	transcriptional regulator
MNQ99_06215	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
MNQ99_06235	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
MNQ99_06240	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
MNQ99_06260	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MNQ99_06280	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MNQ99_06285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MNQ99_06290	COG1120	ATPase activity
MNQ99_06295	COG0531	amino acid
MNQ99_06310	COG0437	4 iron, 4 sulfur cluster binding
MNQ99_06335	COG3276	selenocysteine insertion sequence binding
MNQ99_06350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MNQ99_06370	COG0531	amino acid
MNQ99_06375	COG0531	amino acid
MNQ99_06390	COG1217	gtp-binding protein TYPA
MNQ99_06425	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MNQ99_06440	COG2171	N-acyltransferase activity
MNQ99_06445	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MNQ99_06450	COG0765	amino acid transport
MNQ99_06455	COG0765	amino acid transport
MNQ99_06460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MNQ99_06465	COG1126	abc transporter atp-binding protein
MNQ99_06470	COG1611	Belongs to the LOG family
MNQ99_06490	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MNQ99_06495	COG4122	O-methyltransferase activity
MNQ99_06500	COG1595	DNA-templated transcription, initiation
MNQ99_06510	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MNQ99_06525	COG2239	Acts as a magnesium transporter
MNQ99_06535	COG0006	proline dipeptidase activity
MNQ99_06540	COG0613	PHP domain protein
MNQ99_06545	COG2189	Belongs to the N(4) N(6)-methyltransferase family
MNQ99_06550	COG0513	Belongs to the DEAD box helicase family
MNQ99_06565	COG2154	pterin-4-alpha-carbinolamine dehydratase
MNQ99_06580	COG1309	transcriptional regulator
MNQ99_06590	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MNQ99_06595	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MNQ99_06600	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MNQ99_06605	COG3253	May function as heme-dependent peroxidase
MNQ99_06610	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MNQ99_06615	COG0181	hydroxymethylbilane synthase activity
MNQ99_06625	COG0113	porphobilinogen synthase activity
MNQ99_06630	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MNQ99_06640	COG1464	Belongs to the NlpA lipoprotein family
MNQ99_06645	COG2011	ABC-type metal ion transport system permease component
MNQ99_06670	COG0210	DNA helicase
MNQ99_06705	COG3480	Lon protease (S16) C-terminal proteolytic domain
MNQ99_06710	COG1615	UPF0182 protein
MNQ99_06725	COG1842	Phage shock protein A
MNQ99_06735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MNQ99_06740	COG2086	electron transfer activity
MNQ99_06745	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
MNQ99_06750	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MNQ99_06760	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MNQ99_06765	COG0484	heat shock protein binding
MNQ99_06780	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MNQ99_06800	COG0482	sulfurtransferase activity
MNQ99_06825	COG0714	Associated with various cellular activities
MNQ99_06855	COG5000	phosphorelay sensor kinase activity
MNQ99_06855	COG5002	protein histidine kinase activity
MNQ99_06860	COG5401	PFAM Sporulation and spore germination
MNQ99_06865	COG1040	competence protein
MNQ99_06870	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MNQ99_06875	COG3214	Protein conserved in bacteria
MNQ99_06880	COG0653	protein targeting
MNQ99_06915	COG2902	Dehydrogenase
MNQ99_06940	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MNQ99_06970	COG0438	transferase activity, transferring glycosyl groups
MNQ99_07000	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MNQ99_07005	COG1063	alcohol dehydrogenase
MNQ99_07050	COG1537	nuclear-transcribed mRNA catabolic process, no-go decay
MNQ99_07100	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MNQ99_07105	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MNQ99_07115	COG0179	Fumarylacetoacetate (FAA) hydrolase
MNQ99_07125	COG3415	Transposase
MNQ99_07125	COG2801	Transposase and inactivated derivatives
MNQ99_07135	COG1960	acyl-CoA dehydrogenase activity
MNQ99_07140	COG1802	Transcriptional regulator
MNQ99_07165	COG3842	ATPase activity
MNQ99_07180	COG0179	Fumarylacetoacetate (FAA) hydrolase
MNQ99_07245	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MNQ99_07285	COG1028	Short-chain dehydrogenase reductase Sdr
MNQ99_07295	COG2884	Cell division ATP-binding protein ftsE
MNQ99_07300	COG2177	Part of the ABC transporter FtsEX involved in
MNQ99_07305	COG0739	heme binding
MNQ99_07305	COG0741	lytic transglycosylase activity
MNQ99_07305	COG1196	nuclear chromosome segregation
MNQ99_07310	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MNQ99_07315	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
MNQ99_07325	COG3344	reverse transcriptase
MNQ99_07340	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
MNQ99_07345	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
MNQ99_07350	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
MNQ99_07370	COG3559	Exporter of polyketide antibiotics
MNQ99_07375	COG1131	(ABC) transporter
MNQ99_07385	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MNQ99_07405	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
MNQ99_07415	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MNQ99_07420	COG1121	(ABC) transporter
MNQ99_07425	COG0803	Belongs to the bacterial solute-binding protein 9 family
MNQ99_07435	COG0483	inositol monophosphate 1-phosphatase activity
MNQ99_07445	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MNQ99_07455	COG1595	DNA-templated transcription, initiation
MNQ99_07480	COG0508	dehydrogenase complex catalyzes the overall conversion of
MNQ99_07480	COG0567	Dehydrogenase, E1 component
MNQ99_07490	COG1253	flavin adenine dinucleotide binding
MNQ99_07500	COG0803	Belongs to the bacterial solute-binding protein 9 family
MNQ99_07505	COG1121	(ABC) transporter
MNQ99_07520	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MNQ99_07535	COG0537	adenosine 5'-monophosphoramidase activity
MNQ99_07540	COG1643	Atp-dependent helicase
MNQ99_07555	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MNQ99_07555	COG1116	anion transmembrane transporter activity
MNQ99_07580	COG0018	arginyl-trna synthetase
MNQ99_07590	COG0460	homoserine dehydrogenase
MNQ99_07595	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MNQ99_07600	COG0083	homoserine kinase activity
MNQ99_07610	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MNQ99_07615	COG2890	protein-(glutamine-N5) methyltransferase activity
MNQ99_07625	COG1086	Polysaccharide biosynthesis protein
MNQ99_07630	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MNQ99_07645	COG0356	it plays a direct role in the translocation of protons across the membrane
MNQ99_07650	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MNQ99_07655	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MNQ99_07660	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MNQ99_07665	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MNQ99_07670	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MNQ99_07675	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MNQ99_07680	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MNQ99_07690	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MNQ99_07700	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MNQ99_07705	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
MNQ99_07730	COG1902	pentaerythritol trinitrate reductase activity
MNQ99_07735	COG1131	(ABC) transporter
MNQ99_07760	COG2827	Endonuclease containing a URI domain
MNQ99_07765	COG1335	isochorismatase
MNQ99_07770	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MNQ99_07775	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
MNQ99_07785	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MNQ99_07790	COG1234	tRNA 3'-trailer cleavage
MNQ99_07795	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MNQ99_07800	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MNQ99_07805	COG0586	Pfam SNARE associated Golgi protein
MNQ99_07815	COG1131	(ABC) transporter
MNQ99_07840	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MNQ99_07845	COG0420	3'-5' exonuclease activity
MNQ99_07850	COG0419	ATPase involved in DNA repair
MNQ99_07860	COG1414	Transcriptional regulator
MNQ99_07880	COG1028	Short-chain dehydrogenase reductase Sdr
MNQ99_07885	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MNQ99_07900	COG3226	Transcriptional regulator
MNQ99_07930	COG1012	belongs to the aldehyde dehydrogenase family
MNQ99_07945	COG2815	serine threonine protein kinase
MNQ99_07945	COG0515	serine threonine protein kinase
MNQ99_07950	COG2267	carboxylic ester hydrolase activity
MNQ99_07955	COG0508	dehydrogenase complex catalyzes the overall conversion of
MNQ99_07960	COG0022	dehydrogenase e1 component
MNQ99_07970	COG1113	amino acid transport
MNQ99_07985	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MNQ99_07995	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MNQ99_08000	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MNQ99_08020	COG1846	Transcriptional regulator
MNQ99_08025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MNQ99_08035	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MNQ99_08040	COG0579	oxidoreductase
MNQ99_08045	COG0747	negative chemotaxis
MNQ99_08060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MNQ99_08065	COG0601	transmembrane transport
MNQ99_08070	COG0747	negative chemotaxis
MNQ99_08090	COG2070	2-Nitropropane dioxygenase
MNQ99_08105	COG2133	pyrroloquinoline quinone binding
MNQ99_08135	COG0590	tRNA wobble adenosine to inosine editing
MNQ99_08140	COG0129	dihydroxy-acid dehydratase activity
MNQ99_08150	COG0440	acetolactate synthase activity
MNQ99_08155	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MNQ99_08170	COG1136	(ABC) transporter
MNQ99_08205	COG0129	dihydroxy-acid dehydratase activity
MNQ99_08210	COG1126	abc transporter atp-binding protein
MNQ99_08215	COG0765	amino acid transport
MNQ99_08225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MNQ99_08240	COG2186	Transcriptional regulator
MNQ99_08260	COG2197	response regulator
MNQ99_08265	COG4585	Histidine kinase
MNQ99_08270	COG0473	3-isopropylmalate dehydrogenase activity
MNQ99_08275	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MNQ99_08290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MNQ99_08300	COG0179	Fumarylacetoacetate (FAA) hydrolase
MNQ99_08310	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MNQ99_08315	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MNQ99_08335	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MNQ99_08350	COG1414	Transcriptional regulator
MNQ99_08355	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MNQ99_08360	COG0066	3-isopropylmalate dehydratase activity
MNQ99_08365	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MNQ99_08375	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MNQ99_08380	COG1181	Belongs to the D-alanine--D-alanine ligase family
MNQ99_08390	COG1316	TRANSCRIPTIONal
MNQ99_08410	COG1134	teichoic acid transport
MNQ99_08435	COG0463	Glycosyl transferase, family 2
MNQ99_08445	COG0463	Glycosyl transferase, family 2
MNQ99_08500	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MNQ99_08505	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MNQ99_08510	COG1461	Dihydroxyacetone kinase
MNQ99_08520	COG0742	ribosomal rna small subunit methyltransferase
MNQ99_08530	COG0436	Aminotransferase
MNQ99_08535	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MNQ99_08545	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MNQ99_08560	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MNQ99_08565	COG0571	ribonuclease III activity
MNQ99_08570	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MNQ99_08595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MNQ99_08600	COG0318	PFAM AMP-dependent synthetase and ligase
MNQ99_08605	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MNQ99_08610	COG1196	nuclear chromosome segregation
MNQ99_08625	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
MNQ99_08625	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MNQ99_08630	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
MNQ99_08675	COG0477	Major facilitator Superfamily
MNQ99_08695	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MNQ99_08725	COG2514	catechol 2,3-dioxygenase activity
MNQ99_08735	COG0228	four-way junction DNA binding
MNQ99_08740	COG1837	Belongs to the UPF0109 family
MNQ99_08745	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MNQ99_08750	COG0336	Belongs to the RNA methyltransferase TrmD family
MNQ99_08755	COG0335	large ribosomal subunit rRNA binding
MNQ99_08760	COG0681	Belongs to the peptidase S26 family
MNQ99_08770	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MNQ99_08780	COG0792	nuclease activity
MNQ99_08795	COG4974	Belongs to the 'phage' integrase family
MNQ99_08810	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MNQ99_08815	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MNQ99_08830	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
MNQ99_08865	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MNQ99_08885	COG1045	serine acetyltransferase
MNQ99_08895	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MNQ99_08900	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MNQ99_08935	COG2801	Transposase and inactivated derivatives
MNQ99_08945	COG3594	Acyltransferase
MNQ99_08990	COG1134	teichoic acid transport
MNQ99_09025	COG1216	Glycosyl transferase, family 2
MNQ99_09055	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MNQ99_09055	COG2755	lipolytic protein G-D-S-L family
MNQ99_09070	COG0438	transferase activity, transferring glycosyl groups
MNQ99_09075	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MNQ99_09100	COG0629	single-stranded DNA binding
MNQ99_09150	COG0438	transferase activity, transferring glycosyl groups
MNQ99_09165	COG1131	(ABC) transporter
MNQ99_09205	COG0544	peptidyl-prolyl cis-trans isomerase activity
MNQ99_09215	COG0740	serine-type endopeptidase activity
MNQ99_09220	COG0740	serine-type endopeptidase activity
MNQ99_09225	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MNQ99_09230	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MNQ99_09235	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MNQ99_09240	COG0525	valine-tRNA ligase activity
MNQ99_09245	COG3189	MarR family transcriptional regulator
MNQ99_09265	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MNQ99_09270	COG0285	dihydrofolate synthase activity
MNQ99_09280	COG0105	UTP biosynthetic process
MNQ99_09290	COG1530	ribonuclease E activity
MNQ99_09295	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MNQ99_09300	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MNQ99_09310	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MNQ99_09315	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MNQ99_09325	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MNQ99_09335	COG0799	negative regulation of ribosome biogenesis
MNQ99_09355	COG0517	IMP dehydrogenase activity
MNQ99_09355	COG4175	Glycine betaine
MNQ99_09360	COG4176	ABC-type proline glycine betaine transport system permease component
MNQ99_09385	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MNQ99_09390	COG1780	Probably involved in ribonucleotide reductase function
MNQ99_09395	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MNQ99_09400	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MNQ99_09410	COG2217	Heavy metal translocating P-type atpase
MNQ99_09425	COG2132	Multicopper oxidase
MNQ99_09435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MNQ99_09450	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MNQ99_09470	COG1937	Protein conserved in bacteria
MNQ99_09485	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MNQ99_09490	COG3547	Transposase (IS116 IS110 IS902 family)
MNQ99_09530	COG0508	dehydrogenase complex catalyzes the overall conversion of
MNQ99_09535	COG0022	dehydrogenase e1 component
MNQ99_09535	COG0508	dehydrogenase complex catalyzes the overall conversion of
MNQ99_09540	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MNQ99_09545	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MNQ99_09550	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MNQ99_09555	COG2801	Transposase and inactivated derivatives
MNQ99_09555	COG3415	Transposase
MNQ99_09565	COG0589	response to stress
MNQ99_09570	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MNQ99_09570	COG0574	Belongs to the PEP-utilizing enzyme family
MNQ99_09585	COG2217	Heavy metal translocating P-type atpase
MNQ99_09590	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MNQ99_09630	COG2267	carboxylic ester hydrolase activity
MNQ99_09635	COG0277	FAD linked oxidase domain protein
MNQ99_09640	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MNQ99_09650	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MNQ99_09660	COG0492	ferredoxin-NADP+ reductase activity
MNQ99_09665	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MNQ99_09695	COG3387	PFAM Glycoside hydrolase 15-related
MNQ99_09715	COG1234	tRNA 3'-trailer cleavage
MNQ99_09735	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MNQ99_09745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MNQ99_09760	COG2135	peptidase activity
MNQ99_09780	COG0587	DNA-directed DNA polymerase activity
MNQ99_09790	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MNQ99_09800	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MNQ99_09805	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MNQ99_09845	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MNQ99_09850	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MNQ99_09855	COG0217	transcriptional regulatory protein
MNQ99_09860	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MNQ99_09865	COG0632	four-way junction helicase activity
MNQ99_09870	COG2255	four-way junction helicase activity
MNQ99_09885	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MNQ99_09890	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MNQ99_09900	COG1196	nuclear chromosome segregation
MNQ99_09910	COG0124	histidyl-tRNA synthetase
MNQ99_09920	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MNQ99_09935	COG1490	D-aminoacyl-tRNA deacylase activity
MNQ99_09940	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MNQ99_09955	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MNQ99_09970	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MNQ99_09975	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MNQ99_09980	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MNQ99_09985	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MNQ99_09990	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MNQ99_09995	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MNQ99_10000	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MNQ99_10005	COG0540	Belongs to the ATCase OTCase family
MNQ99_10010	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MNQ99_10020	COG0505	Belongs to the CarA family
MNQ99_10025	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MNQ99_10030	COG0284	orotidine-5'-phosphate decarboxylase activity
MNQ99_10040	COG0194	GDP metabolic process
MNQ99_10045	COG1758	RNA polymerase activity
MNQ99_10055	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MNQ99_10070	COG0438	transferase activity, transferring glycosyl groups
MNQ99_10075	COG0596	Alpha beta hydrolase
MNQ99_10080	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MNQ99_10085	COG0495	leucyl-tRNA aminoacylation
MNQ99_10090	COG1307	EDD domain protein, DegV family
MNQ99_10100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MNQ99_10135	COG0268	Binds directly to 16S ribosomal RNA
MNQ99_10145	COG0481	GTPase activity
MNQ99_10180	COG1420	regulation of RNA biosynthetic process
MNQ99_10185	COG0484	heat shock protein binding
MNQ99_10205	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MNQ99_10215	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MNQ99_10220	COG1316	TRANSCRIPTIONal
MNQ99_10225	COG3590	peptidase
MNQ99_10230	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MNQ99_10235	COG1381	Involved in DNA repair and RecF pathway recombination
MNQ99_10240	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MNQ99_10250	COG0167	dihydroorotate dehydrogenase activity
MNQ99_10270	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MNQ99_10275	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MNQ99_10285	COG2188	Transcriptional regulator
MNQ99_10290	COG2801	Transposase and inactivated derivatives
MNQ99_10300	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MNQ99_10305	COG0723	plastoquinol--plastocyanin reductase activity
MNQ99_10310	COG2010	Cytochrome c
MNQ99_10315	COG1845	cytochrome c oxidase, subunit III
MNQ99_10320	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MNQ99_10380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MNQ99_10395	COG0076	glutamate decarboxylase activity
MNQ99_10420	COG2130	NADP-dependent
MNQ99_10430	COG2963	transposase activity
MNQ99_10435	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MNQ99_10440	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MNQ99_10450	COG0242	peptide deformylase activity
MNQ99_10455	COG0823	Involved in the tonB-independent uptake of proteins
MNQ99_10455	COG1506	peptidase
MNQ99_10465	COG2364	Membrane
MNQ99_10485	COG1216	Glycosyl transferase, family 2
MNQ99_10500	COG0805	protein transport
MNQ99_10505	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MNQ99_10515	COG2378	regulation of single-species biofilm formation
MNQ99_10525	COG0545	Peptidyl-prolyl cis-trans isomerase
MNQ99_10530	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
MNQ99_10535	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
MNQ99_10540	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
MNQ99_10550	COG4122	O-methyltransferase activity
MNQ99_10555	COG1222	aaa ATPase
MNQ99_10570	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MNQ99_10580	COG0215	cysteine-tRNA ligase activity
MNQ99_10585	COG1968	undecaprenyl-diphosphatase activity
MNQ99_10590	COG0667	Aldo Keto reductase
MNQ99_10610	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MNQ99_10635	COG3424	synthase
MNQ99_10645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MNQ99_10650	COG0438	transferase activity, transferring glycosyl groups
MNQ99_10660	COG3844	kynureninase activity
MNQ99_10670	COG4941	Belongs to the sigma-70 factor family
MNQ99_10730	COG0297	glycogen (starch) synthase activity
MNQ99_10740	COG2855	membrane
MNQ99_10750	COG0095	Lipoate-protein ligase
MNQ99_10755	COG2076	Multidrug Resistance protein
MNQ99_10780	COG3842	ATPase activity
MNQ99_10800	COG2610	gluconate transmembrane transporter activity
MNQ99_10810	COG0254	rRNA binding
MNQ99_10825	COG1119	ATPase activity
MNQ99_10830	COG0560	Phosphoserine phosphatase
MNQ99_10830	COG3830	Belongs to the UPF0237 family
MNQ99_10835	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MNQ99_10840	COG1028	Short-chain dehydrogenase reductase Sdr
MNQ99_10845	COG1028	Short-chain dehydrogenase reductase Sdr
MNQ99_10865	COG0488	(ABC) transporter
MNQ99_10880	COG2151	metal-sulfur cluster biosynthetic enzyme
MNQ99_10885	COG0396	ATPase activity
MNQ99_10910	COG1131	(ABC) transporter
MNQ99_10935	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MNQ99_10940	COG0109	protoheme IX farnesyltransferase activity
MNQ99_10950	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MNQ99_10955	COG0166	Belongs to the GPI family
MNQ99_10970	COG0363	glucosamine-6-phosphate deaminase activity
MNQ99_10980	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MNQ99_10985	COG0149	triose-phosphate isomerase activity
MNQ99_10990	COG0126	phosphoglycerate kinase activity
MNQ99_11000	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MNQ99_11005	COG1481	regulation of sporulation
MNQ99_11010	COG0391	Required for morphogenesis under gluconeogenic growth conditions
MNQ99_11015	COG1660	Displays ATPase and GTPase activities
MNQ99_11020	COG0322	excinuclease ABC activity
MNQ99_11025	COG0204	Acyl-transferase
MNQ99_11025	COG0318	PFAM AMP-dependent synthetase and ligase
MNQ99_11040	COG1725	Transcriptional regulator
MNQ99_11075	COG1028	Short-chain dehydrogenase reductase Sdr
MNQ99_11080	COG4106	trans-aconitate 2-methyltransferase activity
MNQ99_11090	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MNQ99_11105	COG0477	Major facilitator Superfamily
MNQ99_11115	COG0556	nucleotide-excision repair
MNQ99_11125	COG0237	dephospho-CoA kinase activity
MNQ99_11125	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MNQ99_11135	COG0277	FAD linked oxidase domain protein
MNQ99_11140	COG1672	PFAM Archaeal ATPase
MNQ99_11140	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
MNQ99_11145	COG1739	Uncharacterized protein family UPF0029
MNQ99_11155	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MNQ99_11190	COG0539	negative regulation of cytoplasmic translation
MNQ99_11195	COG4552	Acetyltransferase involved in intracellular survival and related
MNQ99_11205	COG2050	protein possibly involved in aromatic compounds catabolism
MNQ99_11235	COG0009	L-threonylcarbamoyladenylate synthase
MNQ99_11295	COG0469	pyruvate kinase activity
MNQ99_11305	COG0067	glutamate synthase
MNQ99_11305	COG0070	glutamate synthase
MNQ99_11305	COG0069	glutamate synthase activity
MNQ99_11310	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MNQ99_11315	COG0159	tryptophan synthase activity
MNQ99_11320	COG0133	tryptophan synthase activity
MNQ99_11325	COG0134	indole-3-glycerol-phosphate synthase activity
MNQ99_11345	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MNQ99_11355	COG0107	imidazoleglycerol-phosphate synthase activity
MNQ99_11360	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MNQ99_11365	COG0140	phosphoribosyl-ATP diphosphatase activity
MNQ99_11370	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MNQ99_11375	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MNQ99_11380	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MNQ99_11380	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MNQ99_11400	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MNQ99_11410	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MNQ99_11415	COG0242	peptide deformylase activity
MNQ99_11490	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MNQ99_11515	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
MNQ99_11530	COG4974	Belongs to the 'phage' integrase family
MNQ99_11535	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
MNQ99_11545	COG0697	spore germination
MNQ99_11550	COG0183	Belongs to the thiolase family
MNQ99_11555	COG1024	Enoyl-CoA hydratase
MNQ99_11555	COG1250	3-hydroxyacyl-CoA dehydrogenase
MNQ99_11580	COG0028	Belongs to the TPP enzyme family
MNQ99_11590	COG0667	Aldo Keto reductase
MNQ99_11595	COG0137	argininosuccinate synthase activity
MNQ99_11615	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MNQ99_11625	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MNQ99_11630	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MNQ99_11635	COG0531	amino acid
MNQ99_11640	COG1063	alcohol dehydrogenase
MNQ99_11645	COG4213	ABC transporter substrate-binding protein
MNQ99_11655	COG4214	carbohydrate transport
MNQ99_11660	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MNQ99_11665	COG1028	Short-chain dehydrogenase reductase Sdr
MNQ99_11670	COG2354	Protein conserved in bacteria
MNQ99_11675	COG0569	domain protein
MNQ99_11700	COG0756	dUTP diphosphatase activity
MNQ99_11740	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MNQ99_11755	COG4988	ABC transporter
MNQ99_11760	COG1294	oxidase, subunit
MNQ99_11765	COG1271	oxidase subunit
MNQ99_11780	COG0187	DNA topoisomerase II activity
MNQ99_11790	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MNQ99_11800	COG2223	nitrite transmembrane transporter activity
MNQ99_11810	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MNQ99_11815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MNQ99_11820	COG0508	dehydrogenase complex catalyzes the overall conversion of
MNQ99_11830	COG2801	Transposase and inactivated derivatives
MNQ99_11845	COG0793	Belongs to the peptidase S41A family
MNQ99_11845	COG4946	Tricorn protease homolog
MNQ99_11850	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MNQ99_11850	COG0515	serine threonine protein kinase
MNQ99_11855	COG0321	lipoyl(octanoyl) transferase activity
MNQ99_11860	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MNQ99_11890	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
MNQ99_11900	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
MNQ99_11920	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MNQ99_11925	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MNQ99_11930	COG0587	DNA-directed DNA polymerase activity
MNQ99_11940	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MNQ99_11945	COG3599	regulation of cell shape
MNQ99_11955	COG1799	cell septum assembly
MNQ99_11970	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MNQ99_11980	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MNQ99_11985	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MNQ99_11995	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MNQ99_12000	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MNQ99_12015	COG0768	penicillin binding
MNQ99_12025	COG0275	rRNA processing
MNQ99_12030	COG2001	Belongs to the MraZ family
MNQ99_12040	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MNQ99_12045	COG0142	geranyltranstransferase activity
MNQ99_12055	COG1388	LysM domain
MNQ99_12055	COG1705	Flagellar rod assembly protein muramidase FlgJ
MNQ99_12060	COG0515	serine threonine protein kinase
MNQ99_12060	COG2815	serine threonine protein kinase
MNQ99_12065	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
MNQ99_12085	COG1940	carbohydrate kinase activity
MNQ99_12095	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MNQ99_12120	COG1716	ATPase activity
MNQ99_12125	COG0509	glycine decarboxylation via glycine cleavage system
MNQ99_12140	COG1160	GTP binding
MNQ99_12150	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MNQ99_12165	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MNQ99_12170	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MNQ99_12190	COG2079	MmgE PrpD family protein
MNQ99_12195	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MNQ99_12205	COG1051	belongs to the nudix hydrolase family
MNQ99_12215	COG0494	nUDIX hydrolase
MNQ99_12220	COG0504	CTP synthase activity
MNQ99_12225	COG0497	DNA recombination
MNQ99_12230	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MNQ99_12245	COG0647	UMP catabolic process
MNQ99_12280	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MNQ99_12290	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MNQ99_12295	COG2094	Belongs to the DNA glycosylase MPG family
MNQ99_12305	COG0165	Argininosuccinate lyase
MNQ99_12310	COG1438	arginine binding
MNQ99_12315	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MNQ99_12320	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MNQ99_12325	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MNQ99_12330	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MNQ99_12335	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MNQ99_12360	COG0072	phenylalanine-tRNA ligase activity
MNQ99_12360	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MNQ99_12365	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MNQ99_12385	COG2816	NAD+ diphosphatase activity
MNQ99_12390	COG2814	Major facilitator Superfamily
MNQ99_12400	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MNQ99_12405	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MNQ99_12410	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MNQ99_12415	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MNQ99_12430	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MNQ99_12440	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MNQ99_12445	COG0131	Imidazoleglycerol-phosphate dehydratase
MNQ99_12450	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MNQ99_12460	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MNQ99_12470	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MNQ99_12475	COG2813	Specifically methylates the guanine in position
MNQ99_12480	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MNQ99_12485	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MNQ99_12490	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MNQ99_12500	COG2137	regulation of response to DNA damage stimulus
MNQ99_12505	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MNQ99_12520	COG1396	sequence-specific DNA binding
MNQ99_12525	COG1058	Belongs to the CinA family
MNQ99_12525	COG1546	Belongs to the CinA family
MNQ99_12535	COG1674	ftsk spoiiie
MNQ99_12540	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MNQ99_12545	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MNQ99_12550	COG2267	carboxylic ester hydrolase activity
MNQ99_12565	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MNQ99_12570	COG0314	molybdopterin synthase activity
MNQ99_12575	COG0521	Mo-molybdopterin cofactor biosynthetic process
MNQ99_12605	COG3585	molybdate ion transport
MNQ99_12620	COG0612	Peptidase, M16
MNQ99_12625	COG1185	polyribonucleotide nucleotidyltransferase activity
MNQ99_12630	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MNQ99_12650	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MNQ99_12660	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MNQ99_12665	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MNQ99_12700	COG0442	prolyl-tRNA aminoacylation
MNQ99_12710	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MNQ99_12725	COG0750	zinc metalloprotease
MNQ99_12730	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MNQ99_12735	COG0589	response to stress
MNQ99_12750	COG3181	Tripartite tricarboxylate transporter family receptor
MNQ99_12755	COG3290	protein histidine kinase activity
MNQ99_12760	COG4565	transcriptional regulatory protein
MNQ99_12785	COG1960	acyl-CoA dehydrogenase activity
MNQ99_12795	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MNQ99_12800	COG1309	transcriptional regulator
MNQ99_12810	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MNQ99_12815	COG0508	dehydrogenase complex catalyzes the overall conversion of
MNQ99_12820	COG0022	dehydrogenase e1 component
MNQ99_12830	COG1522	sequence-specific DNA binding
MNQ99_12835	COG0686	Belongs to the AlaDH PNT family
MNQ99_12840	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MNQ99_12850	COG3275	phosphorelay sensor kinase activity
MNQ99_12865	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MNQ99_12875	COG0575	Belongs to the CDS family
MNQ99_12880	COG0233	cytoplasmic translational termination
MNQ99_12885	COG0528	UMP kinase activity
MNQ99_12890	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MNQ99_12895	COG0052	Belongs to the universal ribosomal protein uS2 family
MNQ99_12925	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MNQ99_12935	COG2723	6-phospho-beta-galactosidase activity
MNQ99_12950	COG0358	DNA primase activity
MNQ99_12965	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MNQ99_12975	COG0423	glycine-tRNA ligase activity
MNQ99_13005	COG2755	lipolytic protein G-D-S-L family
MNQ99_13020	COG3833	ABC-type maltose transport systems, permease component
MNQ99_13025	COG1175	transmembrane transport
MNQ99_13035	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MNQ99_13040	COG2873	o-acetylhomoserine
MNQ99_13065	COG0765	amino acid transport
MNQ99_13085	COG1802	Transcriptional regulator
MNQ99_13090	COG1228	amidohydrolase
MNQ99_13095	COG1228	amidohydrolase
MNQ99_13100	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MNQ99_13105	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MNQ99_13120	COG2986	histidine ammonia-lyase
MNQ99_13145	COG0156	8-amino-7-oxononanoate synthase activity
MNQ99_13150	COG1063	alcohol dehydrogenase
MNQ99_13155	COG2124	cytochrome p450
MNQ99_13185	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MNQ99_13190	COG0154	amidase activity
MNQ99_13195	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MNQ99_13205	COG0456	acetyltransferase
MNQ99_13205	COG0454	-acetyltransferase
MNQ99_13240	COG0631	protein serine/threonine phosphatase activity
MNQ99_13260	COG0714	Associated with various cellular activities
MNQ99_13290	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MNQ99_13315	COG0424	maF-like protein
MNQ99_13320	COG4770	biotin carboxylase activity
MNQ99_13330	COG0477	Major facilitator Superfamily
MNQ99_13350	COG0745	RESPONSE REGULATOR receiver
MNQ99_13365	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MNQ99_13375	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MNQ99_13385	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MNQ99_13390	COG5002	protein histidine kinase activity
MNQ99_13405	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MNQ99_13430	COG1132	(ABC) transporter
MNQ99_13450	COG0822	iron-sulfur transferase activity
MNQ99_13465	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MNQ99_13470	COG1088	dTDP-glucose 4,6-dehydratase activity
MNQ99_13535	COG3944	biosynthesis protein
MNQ99_13555	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MNQ99_13565	COG2197	response regulator
MNQ99_13570	COG0193	aminoacyl-tRNA hydrolase activity
MNQ99_13575	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MNQ99_13580	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MNQ99_13585	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MNQ99_13615	COG5002	protein histidine kinase activity
MNQ99_13635	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
MNQ99_13650	COG0488	(ABC) transporter
MNQ99_13655	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MNQ99_13660	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MNQ99_13675	COG0084	hydrolase, TatD family'
MNQ99_13680	COG0714	Associated with various cellular activities
MNQ99_13730	COG1376	ErfK ybiS ycfS ynhG family protein
MNQ99_13735	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MNQ99_13795	COG1482	cell wall glycoprotein biosynthetic process
MNQ99_13805	COG1494	fructose-1,6-bisphosphatase
MNQ99_13815	COG0288	reversible hydration of carbon dioxide
MNQ99_13820	COG0114	fumarate hydratase activity
MNQ99_13825	COG1309	transcriptional regulator
MNQ99_13870	COG4585	Histidine kinase
MNQ99_13875	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
MNQ99_13880	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MNQ99_13890	COG1331	Highly conserved protein containing a thioredoxin domain
MNQ99_13900	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MNQ99_13910	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MNQ99_13920	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MNQ99_13940	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MNQ99_13945	COG0559	Belongs to the binding-protein-dependent transport system permease family
MNQ99_13965	COG2801	Transposase and inactivated derivatives
MNQ99_13990	COG1252	NADH dehydrogenase
MNQ99_14015	COG0148	phosphopyruvate hydratase activity
MNQ99_14020	COG3956	TIGRFAM MazG family protein
MNQ99_14025	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MNQ99_14045	COG1079	Belongs to the binding-protein-dependent transport system permease family
MNQ99_14050	COG4603	Belongs to the binding-protein-dependent transport system permease family
MNQ99_14055	COG3845	ABC transporter
MNQ99_14060	COG1744	ABC transporter substrate-binding protein PnrA-like
MNQ99_14065	COG1473	amidohydrolase
MNQ99_14065	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
MNQ99_14075	COG2009	succinate dehydrogenase
MNQ99_14090	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MNQ99_14105	COG0180	Tryptophanyl-tRNA synthetase
MNQ99_14130	COG1131	(ABC) transporter
MNQ99_14155	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MNQ99_14155	COG3608	succinylglutamate desuccinylase aspartoacylase
MNQ99_14160	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MNQ99_14165	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MNQ99_14180	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MNQ99_14180	COG3608	succinylglutamate desuccinylase aspartoacylase
MNQ99_14225	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MNQ99_14230	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MNQ99_14240	COG2072	flavoprotein involved in K transport
MNQ99_14265	COG1653	transport
MNQ99_14270	COG1175	transmembrane transport
MNQ99_14275	COG0395	ABC-type sugar transport system, permease component
MNQ99_14300	COG2838	Isocitrate dehydrogenase
MNQ99_14310	COG0138	bifunctional purine biosynthesis protein purh
MNQ99_14320	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MNQ99_14355	COG0477	Major facilitator Superfamily
MNQ99_14415	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MNQ99_14425	COG0406	alpha-ribazole phosphatase activity
MNQ99_14435	COG0431	NADPH-dependent FMN reductase
MNQ99_14445	COG1846	Transcriptional regulator
MNQ99_14470	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MNQ99_14490	COG0659	secondary active sulfate transmembrane transporter activity
MNQ99_14510	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MNQ99_14565	COG1063	alcohol dehydrogenase
MNQ99_14570	COG1028	Short-chain dehydrogenase reductase Sdr
MNQ99_14575	COG2610	gluconate transmembrane transporter activity
MNQ99_14580	COG3265	gluconokinase activity
MNQ99_14590	COG0028	Belongs to the TPP enzyme family
MNQ99_14620	COG0488	(ABC) transporter
MNQ99_14625	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MNQ99_14625	COG1017	nitric oxide dioxygenase activity
MNQ99_14630	COG0640	Transcriptional regulator
MNQ99_14650	COG3300	MHYT domain
MNQ99_14650	COG5001	Diguanylate cyclase
MNQ99_14660	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
MNQ99_14680	COG1280	lysine exporter protein (LysE YggA)
MNQ99_14685	COG1012	belongs to the aldehyde dehydrogenase family
MNQ99_14700	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
MNQ99_14705	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
MNQ99_14710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MNQ99_14715	COG0174	glutamine synthetase
MNQ99_14730	COG2124	cytochrome p450
MNQ99_14735	COG0833	amino acid
MNQ99_14740	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MNQ99_14755	COG1960	acyl-CoA dehydrogenase activity
MNQ99_14760	COG1012	belongs to the aldehyde dehydrogenase family
MNQ99_14765	COG1250	3-hydroxyacyl-CoA dehydrogenase
MNQ99_14770	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
MNQ99_14775	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MNQ99_14790	COG0477	Major facilitator Superfamily
MNQ99_14800	COG2514	catechol 2,3-dioxygenase activity
MNQ99_14875	COG0789	Transcriptional regulator
MNQ99_14940	COG1028	Short-chain dehydrogenase reductase Sdr
MNQ99_14940	COG3321	synthase
MNQ99_14940	COG0604	alcohol dehydrogenase
MNQ99_14950	COG0135	phosphoribosylanthranilate isomerase activity
MNQ99_14960	COG3634	alkyl hydroperoxide reductase activity
MNQ99_14965	COG2813	Specifically methylates the guanine in position
MNQ99_14970	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MNQ99_14985	COG0697	spore germination
MNQ99_14990	COG0515	serine threonine protein kinase
MNQ99_14990	COG2815	serine threonine protein kinase
MNQ99_14995	COG1414	Transcriptional regulator
MNQ99_15020	COG3842	ATPase activity
MNQ99_15045	COG2801	Transposase and inactivated derivatives
MNQ99_15075	COG0783	Belongs to the Dps family
MNQ99_15090	COG1595	DNA-templated transcription, initiation
MNQ99_15105	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MNQ99_15115	COG3104	oligopeptide transport
MNQ99_15120	COG0702	epimerase
MNQ99_15140	COG2200	EAL domain
MNQ99_15195	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MNQ99_15200	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MNQ99_15225	COG0671	phosphoesterase, PA-phosphatase related
MNQ99_15230	COG0028	Belongs to the TPP enzyme family
MNQ99_15260	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
MNQ99_15260	COG2066	Belongs to the glutaminase family
MNQ99_15265	COG1012	belongs to the aldehyde dehydrogenase family
MNQ99_15275	COG2814	Major facilitator Superfamily
MNQ99_15295	COG4585	Histidine kinase
MNQ99_15300	COG2197	response regulator
MNQ99_15315	COG0702	epimerase
MNQ99_15335	COG2259	Doxx family
MNQ99_15370	COG2149	membrane
MNQ99_15380	COG3012	SEC-C Motif Domain Protein
MNQ99_15390	COG1329	Transcriptional regulator
MNQ99_15420	COG1522	sequence-specific DNA binding
MNQ99_15455	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MNQ99_15465	COG3415	Transposase
MNQ99_15465	COG2801	Transposase and inactivated derivatives
MNQ99_15470	COG0431	NADPH-dependent FMN reductase
MNQ99_15490	COG0739	heme binding
MNQ99_15490	COG1196	nuclear chromosome segregation
MNQ99_15490	COG0741	lytic transglycosylase activity
MNQ99_15515	COG0028	Belongs to the TPP enzyme family
MNQ99_15525	COG1396	sequence-specific DNA binding
MNQ99_15535	COG0475	glutathione-regulated potassium exporter activity
MNQ99_15555	COG1309	transcriptional regulator
MNQ99_15565	COG1760	l-serine dehydratase
MNQ99_15590	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MNQ99_15660	COG0045	succinate-CoA ligase (ADP-forming) activity
MNQ99_15665	COG0668	transmembrane transport
MNQ99_15690	COG1132	(ABC) transporter
MNQ99_15700	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MNQ99_15715	COG0746	molybdenum cofactor guanylyltransferase activity
MNQ99_15730	COG3103	Sh3 type 3 domain protein
MNQ99_15730	COG0791	NLP P60 protein
MNQ99_15730	COG1388	LysM domain
MNQ99_15735	COG0739	heme binding
MNQ99_15750	COG2814	Major facilitator Superfamily
MNQ99_15760	COG1278	Cold shock
MNQ99_15785	COG0745	RESPONSE REGULATOR receiver
MNQ99_15790	COG2205	protein histidine kinase activity
MNQ99_15800	COG0328	RNA-DNA hybrid ribonuclease activity
MNQ99_15810	COG0459	protein refolding
MNQ99_15815	COG2314	TM2 domain
MNQ99_15835	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MNQ99_15930	COG3842	ATPase activity
MNQ99_15940	COG2264	protein methyltransferase activity
MNQ99_15945	COG0277	FAD linked oxidase domain protein
MNQ99_16005	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MNQ99_16010	COG0366	Alpha amylase catalytic
MNQ99_16015	COG0366	Alpha amylase catalytic
MNQ99_16025	COG1295	ribonuclease BN
MNQ99_16050	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MNQ99_16055	COG0215	cysteine-tRNA ligase activity
MNQ99_16060	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
MNQ99_16085	COG5002	protein histidine kinase activity
MNQ99_16095	COG0588	phosphoglycerate mutase activity
MNQ99_16115	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MNQ99_16120	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MNQ99_16145	COG2808	Putative FMN-binding domain
MNQ99_16170	COG1966	Carbon starvation protein
MNQ99_16175	COG0604	alcohol dehydrogenase
MNQ99_16200	COG1505	serine-type exopeptidase activity
MNQ99_16230	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MNQ99_16240	COG1959	2 iron, 2 sulfur cluster binding
MNQ99_16250	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
MNQ99_16265	COG1595	DNA-templated transcription, initiation
MNQ99_16270	COG2062	phosphohistidine phosphatase, SixA
MNQ99_16275	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MNQ99_16285	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MNQ99_16310	COG0745	RESPONSE REGULATOR receiver
MNQ99_16315	COG2205	protein histidine kinase activity
MNQ99_16360	COG0477	Major facilitator Superfamily
MNQ99_16380	COG2814	Major facilitator Superfamily
MNQ99_16380	COG0477	Major facilitator Superfamily
MNQ99_16400	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
MNQ99_16415	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MNQ99_16435	COG1201	RNA secondary structure unwinding
MNQ99_16440	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MNQ99_16450	COG0564	pseudouridine synthase activity
MNQ99_16500	COG1028	Short-chain dehydrogenase reductase Sdr
MNQ99_16505	COG0574	Belongs to the PEP-utilizing enzyme family
MNQ99_16505	COG3848	Pyruvate phosphate dikinase
MNQ99_16510	COG0574	Belongs to the PEP-utilizing enzyme family
MNQ99_16510	COG3848	Pyruvate phosphate dikinase
MNQ99_16520	COG1414	Transcriptional regulator
MNQ99_16530	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MNQ99_16580	COG0343	queuine tRNA-ribosyltransferase activity
MNQ99_16615	COG0351	phosphomethylpyrimidine kinase
MNQ99_16620	COG3706	GGDEF domain
MNQ99_16630	COG0778	Nitroreductase
MNQ99_16640	COG0604	alcohol dehydrogenase
MNQ99_16640	COG3321	synthase
MNQ99_16660	COG0753	catalase activity
MNQ99_16695	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MNQ99_16705	COG0542	response to heat
MNQ99_16715	COG0604	alcohol dehydrogenase
MNQ99_16725	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MNQ99_16730	COG0477	Major facilitator Superfamily
MNQ99_16735	COG1234	tRNA 3'-trailer cleavage
MNQ99_16745	COG0110	maltose O-acetyltransferase activity
MNQ99_16750	COG2205	protein histidine kinase activity
MNQ99_16755	COG0745	RESPONSE REGULATOR receiver
MNQ99_16780	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MNQ99_16785	COG1228	amidohydrolase
MNQ99_16795	COG0477	Major facilitator Superfamily
MNQ99_16800	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MNQ99_16830	COG0366	Alpha amylase catalytic
MNQ99_16835	COG1846	Transcriptional regulator
MNQ99_16840	COG0697	spore germination
MNQ99_16860	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MNQ99_16880	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MNQ99_16885	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MNQ99_16945	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MNQ99_16950	COG1028	Short-chain dehydrogenase reductase Sdr
MNQ99_16955	COG1028	Short-chain dehydrogenase reductase Sdr
MNQ99_16970	COG0252	asparaginase activity
MNQ99_16990	COG0477	Major facilitator Superfamily
MNQ99_17000	COG1414	Transcriptional regulator
MNQ99_17005	COG2807	transmembrane transport
MNQ99_17010	COG2814	Major facilitator Superfamily
MNQ99_17035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MNQ99_17045	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MNQ99_17065	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MNQ99_17070	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MNQ99_17075	COG1012	belongs to the aldehyde dehydrogenase family
MNQ99_17085	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MNQ99_17090	COG1609	Transcriptional regulator
MNQ99_17110	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MNQ99_17120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MNQ99_17185	COG0318	PFAM AMP-dependent synthetase and ligase
MNQ99_17195	COG0511	ligase activity, forming carbon-carbon bonds
MNQ99_17200	COG0439	Biotin carboxylase
MNQ99_17205	COG1116	anion transmembrane transporter activity
MNQ99_17205	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MNQ99_17210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MNQ99_17220	COG1268	BioY protein
MNQ99_17245	COG1024	Enoyl-CoA hydratase
MNQ99_17255	COG1960	acyl-CoA dehydrogenase activity
MNQ99_17260	COG0183	Belongs to the thiolase family
MNQ99_17265	COG1250	3-hydroxyacyl-CoA dehydrogenase
MNQ99_17265	COG1024	Enoyl-CoA hydratase
MNQ99_17275	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MNQ99_17280	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MNQ99_17285	COG0156	8-amino-7-oxononanoate synthase activity
MNQ99_17290	COG2124	cytochrome p450
MNQ99_17295	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MNQ99_17320	COG3842	ATPase activity
MNQ99_17345	COG1012	belongs to the aldehyde dehydrogenase family
MNQ99_17365	COG1228	amidohydrolase
MNQ99_17370	COG0477	Major facilitator Superfamily
MNQ99_17400	COG1396	sequence-specific DNA binding
MNQ99_17410	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MNQ99_17430	COG1116	anion transmembrane transporter activity
MNQ99_17435	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MNQ99_17440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MNQ99_17455	COG1960	acyl-CoA dehydrogenase activity
MNQ99_17460	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MNQ99_17470	COG0318	PFAM AMP-dependent synthetase and ligase
MNQ99_17495	COG3485	protocatechuate 3,4-dioxygenase
MNQ99_17500	COG3485	protocatechuate 3,4-dioxygenase
MNQ99_17505	COG1414	Transcriptional regulator
MNQ99_17525	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MNQ99_17530	COG1846	Transcriptional regulator
MNQ99_17550	COG0179	Fumarylacetoacetate (FAA) hydrolase
MNQ99_17565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MNQ99_17575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MNQ99_17580	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MNQ99_17585	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MNQ99_17590	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MNQ99_17600	COG0179	Fumarylacetoacetate (FAA) hydrolase
MNQ99_17620	COG1012	belongs to the aldehyde dehydrogenase family
MNQ99_17625	COG2423	ornithine cyclodeaminase activity
MNQ99_17640	COG0183	Belongs to the thiolase family
MNQ99_17650	COG1902	pentaerythritol trinitrate reductase activity
MNQ99_17650	COG0446	pyridine nucleotide-disulphide oxidoreductase
MNQ99_17675	COG1129	ABC transporter
MNQ99_17680	COG1172	Belongs to the binding-protein-dependent transport system permease family
MNQ99_17685	COG4211	Belongs to the binding-protein-dependent transport system permease family
MNQ99_17715	COG2515	1-aminocyclopropane-1-carboxylate deaminase
MNQ99_17725	COG1113	amino acid transport
MNQ99_17790	COG4115	mRNA cleavage
MNQ99_17795	COG2161	toxin-antitoxin pair type II binding
MNQ99_17810	COG2814	Major facilitator Superfamily
MNQ99_17875	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MNQ99_17900	COG0765	amino acid transport
MNQ99_17905	COG0765	amino acid transport
MNQ99_17910	COG1126	abc transporter atp-binding protein
MNQ99_17940	COG1846	Transcriptional regulator
MNQ99_17970	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MNQ99_17975	COG0047	phosphoribosylformylglycinamidine synthase activity
MNQ99_17980	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MNQ99_18000	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
MNQ99_18005	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MNQ99_18010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MNQ99_18015	COG0477	Major facilitator Superfamily
MNQ99_18020	COG1957	nucleoside hydrolase
MNQ99_18025	COG1609	Transcriptional regulator
MNQ99_18045	COG2315	Protein conserved in bacteria
MNQ99_18075	COG1832	CoA-binding protein
MNQ99_18095	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MNQ99_18100	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MNQ99_18130	COG1832	CoA-binding protein
MNQ99_18145	COG0438	transferase activity, transferring glycosyl groups
MNQ99_18150	COG0438	transferase activity, transferring glycosyl groups
MNQ99_18180	COG1216	Glycosyl transferase, family 2
MNQ99_18185	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MNQ99_18190	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MNQ99_18195	COG0076	glutamate decarboxylase activity
MNQ99_18250	COG2271	Major facilitator Superfamily
MNQ99_18265	COG1116	anion transmembrane transporter activity
MNQ99_18270	COG4107	phosphonate C-P lyase system protein PhnK
MNQ99_18275	COG3627	carbon phosphorus lyase activity
MNQ99_18285	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
MNQ99_18295	COG2188	Transcriptional regulator
MNQ99_18300	COG3639	organic phosphonate transmembrane transporter activity
MNQ99_18305	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MNQ99_18365	COG1793	dna ligase
MNQ99_18405	COG1192	Involved in chromosome partitioning
MNQ99_18495	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
MNQ99_18525	COG0251	oxidation-reduction process
MNQ99_18530	COG1012	belongs to the aldehyde dehydrogenase family
MNQ99_18535	COG0154	amidase activity
MNQ99_18560	COG3069	C4-dicarboxylate transmembrane transporter activity
MNQ99_18625	COG0022	dehydrogenase e1 component
MNQ99_18695	COG1063	alcohol dehydrogenase
MNQ99_18735	COG2207	Transcriptional regulator
MNQ99_18740	COG2072	flavoprotein involved in K transport
MNQ99_18795	COG1028	Short-chain dehydrogenase reductase Sdr
MNQ99_18800	COG1012	belongs to the aldehyde dehydrogenase family
MNQ99_18805	COG1116	anion transmembrane transporter activity
MNQ99_18810	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MNQ99_18815	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MNQ99_18830	COG0657	acetylesterase activity
MNQ99_18835	COG2072	flavoprotein involved in K transport
MNQ99_18845	COG1028	Short-chain dehydrogenase reductase Sdr
MNQ99_18860	COG1028	Short-chain dehydrogenase reductase Sdr
MNQ99_18865	COG0477	Major facilitator Superfamily
MNQ99_18870	COG0511	ligase activity, forming carbon-carbon bonds
MNQ99_18870	COG5016	pyruvate
MNQ99_18875	COG0511	ligase activity, forming carbon-carbon bonds
MNQ99_18880	COG0439	Biotin carboxylase
MNQ99_18885	COG1609	Transcriptional regulator
MNQ99_18895	COG1122	ATPase activity
MNQ99_18900	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MNQ99_18905	COG1268	BioY protein
MNQ99_18980	COG1131	(ABC) transporter