locus-tag	class	description
N39L_00050	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
N39L_00120	COG1598	PFAM Uncharacterised protein family UPF0150
N39L_00240	COG1454	alcohol dehydrogenase
N39L_00250	COG0028	Belongs to the TPP enzyme family
N39L_00250	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
N39L_00630	COG1215	transferase activity, transferring glycosyl groups
N39L_00690	COG0220	tRNA (guanine-N7-)-methyltransferase activity
N39L_00750	COG1797	cobyrinic acid a,c-diamide synthase activity
N39L_00790	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
N39L_00800	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
N39L_00800	COG0237	dephospho-CoA kinase activity
N39L_00810	COG0586	Pfam SNARE associated Golgi protein
N39L_00820	COG1366	Belongs to the anti-sigma-factor antagonist family
N39L_00860	COG1619	proteins homologs of microcin C7 resistance protein MccF
N39L_00910	COG1489	DNA binding
N39L_00970	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
N39L_01010	COG0037	tRNA processing
N39L_01020	COG0463	Glycosyl transferase, family 2
N39L_01040	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
N39L_01060	COG0745	RESPONSE REGULATOR receiver
N39L_01070	COG3411	Ferredoxin
N39L_01080	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
N39L_01090	COG0459	protein refolding
N39L_01120	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
N39L_01150	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
N39L_01160	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
N39L_01190	COG0242	peptide deformylase activity
N39L_01230	COG1836	PFAM Integral membrane protein DUF92
N39L_01320	COG0357	Ribosomal RNA small subunit methyltransferase G
N39L_01340	COG0616	signal peptide processing
N39L_01350	COG0697	spore germination
N39L_01380	COG2003	Belongs to the UPF0758 family
N39L_01450	COG1741	Belongs to the pirin family
N39L_01460	COG1007	ATP synthesis coupled electron transport
N39L_01470	COG0500	methyltransferase
N39L_01480	COG2226	methyltransferase
N39L_01490	COG1280	lysine exporter protein (LysE YggA)
N39L_01500	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
N39L_01510	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
N39L_01530	COG0826	peptidase U32
N39L_01550	COG4221	oxidoreductase activity
N39L_01560	COG0156	8-amino-7-oxononanoate synthase activity
N39L_01580	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N39L_01590	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N39L_01610	COG0484	heat shock protein binding
N39L_01640	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N39L_01700	COG0529	Catalyzes the synthesis of activated sulfate
N39L_01730	COG0438	transferase activity, transferring glycosyl groups
N39L_01760	COG3409	Peptidoglycan-binding domain 1 protein
N39L_01760	COG3429	Glucose-6-phosphate dehydrogenase subunit
N39L_01770	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
N39L_01780	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
N39L_01820	COG1271	oxidase subunit
N39L_01860	COG3000	fatty acid hydroxylase
N39L_01860	COG0300	oxidoreductase activity
N39L_01890	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
N39L_01900	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
N39L_01940	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
N39L_01950	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
N39L_01970	COG0514	ATP-dependent DNA helicase (RecQ)
N39L_01980	COG0514	ATP-dependent DNA helicase (RecQ)
N39L_02030	COG4251	negative regulation of phosphorylation
N39L_02040	COG4251	negative regulation of phosphorylation
N39L_02110	COG0668	transmembrane transport
N39L_02390	COG2912	Transglutaminase-like superfamily
N39L_02400	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
N39L_02430	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N39L_02440	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
N39L_02450	COG1268	BioY protein
N39L_02460	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
N39L_02490	COG0581	inorganic phosphate transmembrane transporter activity
N39L_02500	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
N39L_02510	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
N39L_02690	COG0009	L-threonylcarbamoyladenylate synthase
N39L_02700	COG5002	protein histidine kinase activity
N39L_02700	COG2198	Histidine kinase
N39L_02700	COG0784	Response regulator, receiver
N39L_02710	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
N39L_02730	COG1376	ErfK ybiS ycfS ynhG family protein
N39L_02750	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
N39L_02760	COG1472	Belongs to the glycosyl hydrolase 3 family
N39L_02780	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
N39L_02830	COG3266	domain, Protein
N39L_02830	COG2911	Protein conserved in bacteria
N39L_02830	COG1361	Conserved repeat domain
N39L_02840	COG0793	Belongs to the peptidase S41A family
N39L_02860	COG0745	RESPONSE REGULATOR receiver
N39L_02870	COG0730	response to heat
N39L_02890	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
N39L_02890	COG3264	Mechanosensitive ion channel
N39L_02900	COG1943	Transposase
N39L_02930	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
N39L_02940	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
N39L_02950	COG0017	Asparaginyl-tRNA synthetase
N39L_03080	COG0105	UTP biosynthetic process
N39L_03090	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
N39L_03160	COG0784	Response regulator, receiver
N39L_03160	COG3437	response regulator, receiver
N39L_03170	COG3852	Histidine kinase
N39L_03190	COG0297	glycogen (starch) synthase activity
N39L_03210	COG5002	protein histidine kinase activity
N39L_03220	COG0702	epimerase
N39L_03230	COG0330	HflC and HflK could
N39L_03270	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
N39L_03280	COG1032	radical SAM domain protein
N39L_03290	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
N39L_03300	COG1381	Involved in DNA repair and RecF pathway recombination
N39L_03320	COG0270	DNA (cytosine-5-)-methyltransferase activity
N39L_03360	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
N39L_03370	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
N39L_03370	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
N39L_03380	COG3063	Type IV pilus biogenesis stability protein PilW
N39L_03400	COG0222	ribosome binding
N39L_03410	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
N39L_03420	COG0081	regulation of translation
N39L_03430	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
N39L_03440	COG0250	Participates in transcription elongation, termination and antitermination
N39L_03450	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
N39L_03460	COG0335	large ribosomal subunit rRNA binding
N39L_03470	COG0752	glycyl-tRNA synthetase alpha subunit
N39L_03520	COG2205	protein histidine kinase activity
N39L_03540	COG0494	nUDIX hydrolase
N39L_03550	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
N39L_03570	COG0601	transmembrane transport
N39L_03590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N39L_03870	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
N39L_03880	COG3932	Exopolysaccharide synthesis, ExoD
N39L_03910	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
N39L_03910	COG0284	orotidine-5'-phosphate decarboxylase activity
N39L_03940	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
N39L_03950	COG1882	Formate acetyltransferase
N39L_03960	COG0537	adenosine 5'-monophosphoramidase activity
N39L_04020	COG1695	Transcriptional regulator
N39L_04030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N39L_04050	COG2119	membrane
N39L_04060	COG1640	4-alpha-glucanotransferase
N39L_04070	COG1426	Protein conserved in bacteria
N39L_04080	COG1187	pseudouridine synthase activity
N39L_04100	COG0575	Belongs to the CDS family
N39L_04120	COG1982	Orn Lys Arg decarboxylase major
N39L_04130	COG0012	GTP binding
N39L_04140	COG1950	PFAM Membrane protein of
N39L_04170	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
N39L_04180	COG0306	phosphate transporter
N39L_04350	COG1598	PFAM Uncharacterised protein family UPF0150
N39L_04390	COG2886	Uncharacterised protein family (UPF0175)
N39L_04470	COG1598	PFAM Uncharacterised protein family UPF0150
N39L_04540	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
N39L_04580	COG5002	protein histidine kinase activity
N39L_04620	COG2027	D-alanyl-D-alanine carboxypeptidase
N39L_04630	COG2045	Belongs to the ComB family
N39L_04640	COG0515	serine threonine protein kinase
N39L_04640	COG1357	PFAM Pentapeptide repeats (8 copies)
N39L_04650	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
N39L_04890	COG0768	penicillin binding
N39L_04910	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
N39L_04970	COG0754	glutathionylspermidine amidase activity
N39L_05040	COG0598	Magnesium transport protein CorA
N39L_05050	COG3266	domain, Protein
N39L_05050	COG0515	serine threonine protein kinase
N39L_05060	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
N39L_05070	COG0840	transmembrane signaling receptor activity
N39L_05090	COG0784	Response regulator, receiver
N39L_05090	COG2205	protein histidine kinase activity
N39L_05100	COG1543	Belongs to the glycosyl hydrolase 57 family
N39L_05180	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
N39L_05220	COG0745	RESPONSE REGULATOR receiver
N39L_05230	COG0745	RESPONSE REGULATOR receiver
N39L_05310	COG0515	serine threonine protein kinase
N39L_05310	COG1357	PFAM Pentapeptide repeats (8 copies)
N39L_05330	COG1181	Belongs to the D-alanine--D-alanine ligase family
N39L_05360	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
N39L_05590	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
N39L_05720	COG1111	helicase
N39L_05720	COG1205	dead DEAH box helicase
N39L_05770	COG1201	RNA secondary structure unwinding
N39L_05870	COG4251	negative regulation of phosphorylation
N39L_05870	COG2203	Gaf domain
N39L_05870	COG3706	GGDEF domain
N39L_05870	COG5001	Diguanylate cyclase
N39L_05890	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
N39L_05910	COG3937	granule-associated protein
N39L_05920	COG0489	protein tyrosine kinase activity
N39L_05940	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
N39L_05960	COG1404	Belongs to the peptidase S8 family
N39L_05960	COG4935	Belongs to the peptidase S8 family
N39L_05980	COG0271	Belongs to the BolA IbaG family
N39L_05990	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
N39L_06020	COG0745	RESPONSE REGULATOR receiver
N39L_06030	COG1012	belongs to the aldehyde dehydrogenase family
N39L_06080	COG0643	Histidine kinase
N39L_06080	COG0784	Response regulator, receiver
N39L_06080	COG2198	Histidine kinase
N39L_06090	COG5002	protein histidine kinase activity
N39L_06130	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
N39L_06190	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
N39L_06200	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
N39L_06230	COG1295	ribonuclease BN
N39L_06250	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
N39L_06280	COG0277	FAD linked oxidase domain protein
N39L_06290	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
N39L_06330	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
N39L_06340	COG0732	type I restriction modification DNA specificity domain
N39L_06360	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N39L_06370	COG3659	wide pore channel activity
N39L_06380	COG3659	wide pore channel activity
N39L_06390	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N39L_06440	COG2046	Belongs to the sulfate adenylyltransferase family
N39L_06680	COG0784	Response regulator, receiver
N39L_06680	COG2205	protein histidine kinase activity
N39L_06720	COG4191	Histidine kinase
N39L_06770	COG0242	peptide deformylase activity
N39L_06780	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N39L_06790	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
N39L_06800	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
N39L_06820	COG0592	DNA-directed DNA polymerase activity
N39L_06870	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N39L_06880	COG1385	rRNA (uridine-N3-)-methyltransferase activity
N39L_06890	COG2084	Dehydrogenase
N39L_06920	COG0316	Belongs to the HesB IscA family
N39L_06950	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
N39L_06960	COG0463	Glycosyl transferase, family 2
N39L_06970	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
N39L_06990	COG1136	(ABC) transporter
N39L_07010	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
N39L_07030	COG1104	cysteine desulfurase activity
N39L_07040	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
N39L_07060	COG5002	protein histidine kinase activity
N39L_07070	COG0745	RESPONSE REGULATOR receiver
N39L_07150	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
N39L_07170	COG3239	Fatty acid desaturase
N39L_07200	COG2226	methyltransferase
N39L_07220	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
N39L_07310	COG0772	Belongs to the SEDS family
N39L_07340	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
N39L_07360	COG0793	Belongs to the peptidase S41A family
N39L_07370	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
N39L_07420	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
N39L_07430	COG1446	asparaginase
N39L_07440	COG0745	RESPONSE REGULATOR receiver
N39L_07450	COG2198	Histidine kinase
N39L_07450	COG0643	Histidine kinase
N39L_07470	COG0840	transmembrane signaling receptor activity
N39L_07490	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
N39L_07490	COG0457	Tetratricopeptide repeat
N39L_07500	COG2201	protein-glutamate methylesterase activity
N39L_07520	COG0863	Belongs to the N(4) N(6)-methyltransferase family
N39L_07550	COG1333	cytochrome c biogenesis protein
N39L_07630	COG0768	penicillin binding
N39L_07650	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
N39L_07660	COG4095	Psort location CytoplasmicMembrane, score
N39L_07700	COG4447	cellulose binding
N39L_07710	COG1773	rubredoxin
N39L_07720	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
N39L_07730	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
N39L_07740	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
N39L_07760	COG0612	Peptidase, M16
N39L_07780	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
N39L_07790	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
N39L_07800	COG0815	Transfers the fatty acyl group on membrane lipoproteins
N39L_07820	COG4251	negative regulation of phosphorylation
N39L_07850	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
N39L_07860	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
N39L_07870	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
N39L_07880	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
N39L_07890	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
N39L_07900	COG0356	it plays a direct role in the translocation of protons across the membrane
N39L_07920	COG0442	prolyl-tRNA aminoacylation
N39L_07930	COG1555	photosystem II stabilization
N39L_07930	COG1596	polysaccharide export
N39L_07950	COG1104	cysteine desulfurase activity
N39L_07960	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
N39L_07970	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
N39L_07970	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
N39L_08150	COG4636	protein conserved in cyanobacteria
N39L_08160	COG4636	protein conserved in cyanobacteria
N39L_08430	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
N39L_08510	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
N39L_08720	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
N39L_08730	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
N39L_08910	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
N39L_08920	COG0735	belongs to the Fur family
N39L_08930	COG3409	Peptidoglycan-binding domain 1 protein
N39L_08930	COG0860	N-Acetylmuramoyl-L-alanine amidase
N39L_08970	COG0673	inositol 2-dehydrogenase activity
N39L_08990	COG2385	sporulation resulting in formation of a cellular spore
N39L_09020	COG0574	Belongs to the PEP-utilizing enzyme family
N39L_09020	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
N39L_09030	COG1733	regulation of RNA biosynthetic process
N39L_09040	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
N39L_09040	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
N39L_09080	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
N39L_09080	COG0617	tRNA 3'-terminal CCA addition
N39L_09080	COG0517	IMP dehydrogenase activity
N39L_09120	COG0483	inositol monophosphate 1-phosphatase activity
N39L_09210	COG1216	Glycosyl transferase, family 2
N39L_09340	COG1131	(ABC) transporter
N39L_09350	COG0745	RESPONSE REGULATOR receiver
N39L_09430	COG0302	gtp cyclohydrolase
N39L_09450	COG0523	cobalamin synthesis protein
N39L_09510	COG1022	Amp-dependent synthetase and ligase
N39L_09540	COG0659	secondary active sulfate transmembrane transporter activity
N39L_09550	COG0659	secondary active sulfate transmembrane transporter activity
N39L_09560	COG1175	transmembrane transport
N39L_09580	COG2911	Protein conserved in bacteria
N39L_09580	COG1361	Conserved repeat domain
N39L_09580	COG3266	domain, Protein
N39L_09600	COG0402	S-adenosylhomocysteine deaminase activity
N39L_09620	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
N39L_09630	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N39L_09640	COG2226	methyltransferase
N39L_09700	COG2319	Wd-40 repeat
N39L_09700	COG3903	Transcriptional regulator
N39L_09730	COG0589	response to stress
N39L_09740	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
N39L_09760	COG1217	gtp-binding protein TYPA
N39L_09770	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
N39L_09790	COG1555	photosystem II stabilization
N39L_09810	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
N39L_09900	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
N39L_09920	COG1840	ABC-type Fe3 transport system, periplasmic component
N39L_09950	COG3659	wide pore channel activity
N39L_09980	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
N39L_09990	COG0114	fumarate hydratase activity
N39L_10110	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
N39L_10120	COG0824	Thioesterase
N39L_10160	COG0404	The glycine cleavage system catalyzes the degradation of glycine
N39L_10190	COG0745	RESPONSE REGULATOR receiver
N39L_10230	COG0006	proline dipeptidase activity
N39L_10240	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
N39L_10250	COG0812	UDP-N-acetylmuramate dehydrogenase activity
N39L_10260	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
N39L_10270	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
N39L_10280	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
N39L_10300	COG2124	cytochrome p450
N39L_10310	COG1575	Belongs to the MenA family. Type 1 subfamily
N39L_10380	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
N39L_10460	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
N39L_10470	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
N39L_10490	COG1131	(ABC) transporter
N39L_10530	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
N39L_10540	COG0189	ligase activity
N39L_10570	COG0440	acetolactate synthase activity
N39L_10580	COG0475	glutathione-regulated potassium exporter activity
N39L_10620	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
N39L_10640	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
N39L_10680	COG0784	Response regulator, receiver
N39L_10680	COG2205	protein histidine kinase activity
N39L_10690	COG0588	phosphoglycerate mutase activity
N39L_10700	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
N39L_10730	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
N39L_10740	COG0552	protein localization to endoplasmic reticulum
N39L_10740	COG0552	protein localization to endoplasmic reticulum
N39L_10750	COG2208	phosphoserine phosphatase activity
N39L_10770	COG0165	Argininosuccinate lyase
N39L_10890	COG0484	heat shock protein binding
N39L_10900	COG0443	Heat shock 70 kDa protein
N39L_10910	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
N39L_10910	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N39L_10950	COG0513	Belongs to the DEAD box helicase family
N39L_11010	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
N39L_11080	COG0724	RNA recognition motif
N39L_11090	COG1672	PFAM Archaeal ATPase
N39L_11100	COG1672	PFAM Archaeal ATPase
N39L_11110	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
N39L_11200	COG1122	ATPase activity
N39L_11260	COG0772	Belongs to the SEDS family
N39L_11280	COG0768	penicillin binding
N39L_11330	COG1115	amino acid carrier protein
N39L_11340	COG0107	imidazoleglycerol-phosphate synthase activity
N39L_11690	COG0501	Belongs to the peptidase M48B family
N39L_11700	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
N39L_11720	COG0686	Belongs to the AlaDH PNT family
N39L_11740	COG1040	competence protein
N39L_11750	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
N39L_11770	COG3659	wide pore channel activity
N39L_12050	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
N39L_12060	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
N39L_12120	COG1215	transferase activity, transferring glycosyl groups
N39L_12130	COG2815	serine threonine protein kinase
N39L_12130	COG0515	serine threonine protein kinase
N39L_12140	COG3852	Histidine kinase
N39L_12150	COG2814	Major facilitator Superfamily
N39L_12160	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
N39L_12160	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
N39L_12170	COG0339	signal peptide processing
N39L_12260	COG0308	aminopeptidase N
N39L_12270	COG0436	Aminotransferase
N39L_12280	COG1254	Belongs to the acylphosphatase family
N39L_12310	COG1012	belongs to the aldehyde dehydrogenase family
N39L_12330	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
N39L_12340	COG0583	DNA-binding transcription factor activity
N39L_12370	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
N39L_12390	COG0572	uridine kinase
N39L_12400	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
N39L_12430	COG0792	nuclease activity
N39L_12450	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
N39L_12460	COG0333	Belongs to the bacterial ribosomal protein bL32 family
N39L_12480	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
N39L_12510	COG0840	transmembrane signaling receptor activity
N39L_12520	COG1073	alpha beta
N39L_12660	COG4372	Transposase
N39L_12670	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N39L_12680	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
N39L_12690	COG0131	Imidazoleglycerol-phosphate dehydratase
N39L_12700	COG0793	Belongs to the peptidase S41A family
N39L_12710	COG3903	Transcriptional regulator
N39L_12710	COG2319	Wd-40 repeat
N39L_12720	COG0793	Belongs to the peptidase S41A family
N39L_12740	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
N39L_12740	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
N39L_12790	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
N39L_12830	COG0628	permease
N39L_12860	COG4968	Prepilin-type N-terminal cleavage methylation domain
N39L_12900	COG1215	transferase activity, transferring glycosyl groups
N39L_12960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N39L_13040	COG1252	NADH dehydrogenase
N39L_13050	COG0315	cyclic pyranopterin monophosphate synthase activity
N39L_13060	COG0574	Belongs to the PEP-utilizing enzyme family
N39L_13060	COG3848	Pyruvate phosphate dikinase
N39L_13100	COG0318	PFAM AMP-dependent synthetase and ligase
N39L_13130	COG0728	peptidoglycan biosynthetic process
N39L_13200	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N39L_13210	COG0110	maltose O-acetyltransferase activity
N39L_13220	COG0010	Belongs to the arginase family
N39L_13240	COG0528	UMP kinase activity
N39L_13250	COG0233	cytoplasmic translational termination
N39L_13270	COG3706	GGDEF domain
N39L_13270	COG2203	Gaf domain
N39L_13270	COG4251	negative regulation of phosphorylation
N39L_13270	COG5001	Diguanylate cyclase
N39L_13280	COG2010	Cytochrome c
N39L_13290	COG0312	modulator of DNA gyrase
N39L_13340	COG0489	protein tyrosine kinase activity
N39L_13380	COG1049	propionate catabolic process, 2-methylcitrate cycle
N39L_13470	COG1192	Involved in chromosome partitioning
N39L_13510	COG2197	response regulator
N39L_13540	COG1475	DNA binding
N39L_13740	COG1253	flavin adenine dinucleotide binding
N39L_13750	COG1597	lipid kinase activity
N39L_13750	COG1803	Methylglyoxal synthase
N39L_13760	COG2217	Heavy metal translocating P-type atpase
N39L_13850	COG0542	response to heat
N39L_13870	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
N39L_13890	COG3659	wide pore channel activity
N39L_13980	COG0129	dihydroxy-acid dehydratase activity
N39L_14010	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
N39L_14030	COG0419	ATPase involved in DNA repair
N39L_14060	COG1032	radical SAM domain protein
N39L_14070	COG0156	8-amino-7-oxononanoate synthase activity
N39L_14110	COG0318	PFAM AMP-dependent synthetase and ligase
N39L_14140	COG0047	phosphoribosylformylglycinamidine synthase activity
N39L_14150	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
N39L_14160	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
N39L_14270	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N39L_14510	COG1459	type II secretion system
N39L_14530	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
N39L_14540	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
N39L_14550	COG0443	Heat shock 70 kDa protein
N39L_14560	COG0484	heat shock protein binding
N39L_14580	COG1162	GTPase activity
N39L_14600	COG0243	molybdopterin cofactor binding
N39L_14610	COG2223	nitrite transmembrane transporter activity
N39L_14630	COG0402	S-adenosylhomocysteine deaminase activity
N39L_14640	COG1596	polysaccharide export
N39L_14690	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N39L_14740	COG1028	Short-chain dehydrogenase reductase Sdr
N39L_14760	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
N39L_14810	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
N39L_15000	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
N39L_15010	COG0719	Fe-S assembly protein
N39L_15020	COG0396	ATPase activity
N39L_15030	COG0719	Fe-S assembly protein
N39L_15060	COG2255	four-way junction helicase activity
N39L_15170	COG0460	homoserine dehydrogenase
N39L_15180	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N39L_15210	COG1295	ribonuclease BN
N39L_15250	COG0803	Belongs to the bacterial solute-binding protein 9 family
N39L_15270	COG1108	ABC-type Mn2 Zn2 transport systems permease components
N39L_15360	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
N39L_15370	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
N39L_15380	COG0019	diaminopimelate decarboxylase activity
N39L_15400	COG0542	response to heat
N39L_15430	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
N39L_15440	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
N39L_15450	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
N39L_15460	COG5002	protein histidine kinase activity
N39L_15510	COG1473	amidohydrolase
N39L_15540	COG0601	transmembrane transport
N39L_15550	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
N39L_15590	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
N39L_15620	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
N39L_15640	COG0521	Mo-molybdopterin cofactor biosynthetic process
N39L_15650	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
N39L_15660	COG2154	pterin-4-alpha-carbinolamine dehydratase
N39L_15670	COG2340	Cysteine-rich secretory protein family
N39L_15690	COG2890	protein-(glutamine-N5) methyltransferase activity
N39L_15770	COG1260	myo-inositol-1-phosphate synthase
N39L_16000	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
N39L_16110	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
N39L_16120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N39L_16130	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
N39L_16140	COG0395	ABC-type sugar transport system, permease component
N39L_16200	COG0489	protein tyrosine kinase activity
N39L_16210	COG0408	coproporphyrinogen oxidase activity
N39L_16250	COG0739	heme binding
N39L_16260	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
N39L_16270	COG0587	DNA-directed DNA polymerase activity
N39L_16280	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
N39L_16300	COG1842	Phage shock protein A
N39L_16330	COG2197	response regulator
N39L_16370	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
N39L_16420	COG0842	Transport permease protein
N39L_16420	COG1131	(ABC) transporter
N39L_16420	COG1716	ATPase activity
N39L_16440	COG1215	transferase activity, transferring glycosyl groups
N39L_16460	COG0110	maltose O-acetyltransferase activity
N39L_16530	COG0642	Histidine kinase
N39L_16550	COG1725	Transcriptional regulator
N39L_16560	COG0412	Dienelactone hydrolase
N39L_16570	COG0539	negative regulation of cytoplasmic translation
N39L_16580	COG2971	BadF BadG BcrA BcrD
N39L_16610	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
N39L_16640	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
N39L_16750	COG3266	domain, Protein
N39L_16750	COG0515	serine threonine protein kinase
N39L_16890	COG0542	response to heat
N39L_16940	COG5002	protein histidine kinase activity
N39L_16960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N39L_16960	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
N39L_17010	COG2217	Heavy metal translocating P-type atpase
N39L_17020	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
N39L_17040	COG1413	lyase activity
N39L_17050	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
N39L_17060	COG0237	dephospho-CoA kinase activity
N39L_17100	COG0601	transmembrane transport
N39L_17120	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
N39L_17130	COG0629	single-stranded DNA binding
N39L_17190	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
N39L_17250	COG0321	lipoyl(octanoyl) transferase activity
N39L_17400	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
N39L_17510	COG2192	nodulation
N39L_17560	COG0277	FAD linked oxidase domain protein
N39L_17560	COG0247	lactate metabolic process
N39L_17580	COG0740	serine-type endopeptidase activity
N39L_17600	COG0557	exoribonuclease II activity
N39L_17630	COG0776	regulation of translation
N39L_17650	COG1429	ligase activity, forming nitrogen-metal bonds
N39L_17660	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
N39L_17670	COG0569	domain protein
N39L_17710	COG0501	Belongs to the peptidase M48B family
N39L_17730	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
N39L_17740	COG1361	Conserved repeat domain
N39L_17740	COG2911	Protein conserved in bacteria
N39L_17740	COG3266	domain, Protein
N39L_17790	COG0463	Glycosyl transferase, family 2
N39L_17790	COG1216	Glycosyl transferase, family 2
N39L_17890	COG0438	transferase activity, transferring glycosyl groups
N39L_17920	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
N39L_18300	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
N39L_18310	COG0375	protein maturation
N39L_18320	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
N39L_18330	COG0205	6-phosphofructokinase activity
N39L_18350	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
N39L_18490	COG1702	phosphate starvation-inducible protein PhoH
N39L_18510	COG0228	four-way junction DNA binding
N39L_18520	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
N39L_18590	COG1122	ATPase activity
N39L_18710	COG0516	GMP reductase activity
N39L_18710	COG0517	IMP dehydrogenase activity
N39L_18740	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
N39L_18780	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
N39L_18810	COG0215	cysteine-tRNA ligase activity
N39L_18830	COG0523	cobalamin synthesis protein
N39L_18840	COG2166	iron-sulfur cluster assembly
N39L_18850	COG0113	porphobilinogen synthase activity
N39L_18900	COG0004	ammonium transporteR
N39L_18910	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
N39L_18940	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
N39L_19000	COG0596	Alpha beta hydrolase
N39L_19020	COG0538	isocitrate dehydrogenase activity
N39L_19030	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
N39L_19040	COG2197	response regulator
N39L_19050	COG0303	'Molybdopterin
N39L_19070	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
N39L_19110	COG0784	Response regulator, receiver
N39L_19110	COG2198	Histidine kinase
N39L_19110	COG2205	protein histidine kinase activity
N39L_19130	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
N39L_19150	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
N39L_19180	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
N39L_19180	COG0512	Glutamine amidotransferase of anthranilate synthase
N39L_19190	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
N39L_19200	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
N39L_19650	COG0617	tRNA 3'-terminal CCA addition
N39L_19750	COG4251	negative regulation of phosphorylation
N39L_19750	COG5001	Diguanylate cyclase
N39L_19750	COG3706	GGDEF domain
N39L_19750	COG2203	Gaf domain
N39L_19770	COG0515	serine threonine protein kinase
N39L_19770	COG1357	PFAM Pentapeptide repeats (8 copies)
N39L_19900	COG1214	PFAM Peptidase M22, glycoprotease
N39L_19970	COG3409	Peptidoglycan-binding domain 1 protein
N39L_19980	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
N39L_20020	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
N39L_20020	COG0189	ligase activity
N39L_20030	COG4242	Belongs to the peptidase S51 family
N39L_20040	COG0336	Belongs to the RNA methyltransferase TrmD family
N39L_20080	COG0589	response to stress
N39L_20080	COG0475	glutathione-regulated potassium exporter activity
N39L_20250	COG0415	Belongs to the DNA photolyase family
N39L_20280	COG1215	transferase activity, transferring glycosyl groups
N39L_20300	COG0857	belongs to the CobB CobQ family
N39L_20540	COG1191	sigma factor activity
N39L_20550	COG0509	glycine decarboxylation via glycine cleavage system
N39L_20600	COG0121	glutamine amidotransferase
N39L_20620	COG0596	Alpha beta hydrolase
N39L_20640	COG2885	chlorophyll binding
N39L_20650	COG2885	chlorophyll binding
N39L_20660	COG0307	riboflavin synthase, alpha
N39L_20680	COG0667	Aldo Keto reductase
N39L_20750	COG0515	serine threonine protein kinase
N39L_20760	COG0583	DNA-binding transcription factor activity
N39L_20770	COG0583	DNA-binding transcription factor activity
N39L_20790	COG3118	belongs to the thioredoxin family
N39L_20810	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
N39L_20820	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
N39L_20830	COG0328	RNA-DNA hybrid ribonuclease activity
N39L_20840	COG0138	bifunctional purine biosynthesis protein purh
N39L_20860	COG0745	RESPONSE REGULATOR receiver
N39L_20880	COG0471	metal ion transport
N39L_20880	COG3273	potassium ion transport
N39L_20890	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
N39L_20910	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
N39L_20920	COG0463	Glycosyl transferase, family 2
N39L_20980	COG2850	peptidyl-arginine hydroxylation
N39L_21020	COG5002	protein histidine kinase activity
N39L_21050	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
N39L_21060	COG0088	Forms part of the polypeptide exit tunnel
N39L_21070	COG0089	rRNA binding
N39L_21080	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
N39L_21090	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
N39L_21100	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
N39L_21110	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
N39L_21120	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
N39L_21130	COG0255	Belongs to the universal ribosomal protein uL29 family
N39L_21140	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
N39L_21150	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
N39L_21160	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
N39L_21170	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
N39L_21180	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
N39L_21190	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
N39L_21200	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
N39L_21210	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
N39L_21220	COG0200	Binds to the 23S rRNA
N39L_21230	COG0201	protein transport
N39L_21240	COG0563	adenylate kinase activity
N39L_21250	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
N39L_21260	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
N39L_21270	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
N39L_21280	COG0202	RNA polymerase activity
N39L_21290	COG0203	ribosomal protein L17
N39L_21300	COG0101	tRNA pseudouridine synthase activity
N39L_21310	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
N39L_21320	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
N39L_21330	COG0254	rRNA binding
N39L_21350	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
N39L_21360	COG2204	response regulator
N39L_21370	COG0488	(ABC) transporter
N39L_21430	COG0484	heat shock protein binding
N39L_21450	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
N39L_21480	COG2226	methyltransferase
N39L_21500	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
N39L_21500	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
N39L_21510	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
N39L_21520	COG2211	Major facilitator Superfamily
N39L_21540	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
N39L_21550	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
N39L_21680	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N39L_21710	COG5002	protein histidine kinase activity
N39L_21730	COG0745	RESPONSE REGULATOR receiver
N39L_21760	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
N39L_21790	COG1196	nuclear chromosome segregation
N39L_21810	COG1196	nuclear chromosome segregation
N39L_21840	COG0134	indole-3-glycerol-phosphate synthase activity
N39L_21870	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
N39L_21880	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
N39L_21900	COG0148	phosphopyruvate hydratase activity
N39L_21910	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
N39L_21950	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
N39L_22000	COG0589	response to stress
N39L_22020	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
N39L_22030	COG2066	Belongs to the glutaminase family
N39L_22220	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
N39L_22230	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
N39L_22410	COG1666	GTP binding
N39L_22880	COG1309	transcriptional regulator
N39L_22890	COG0612	Peptidase, M16
N39L_22900	COG0612	Peptidase, M16
N39L_22910	COG0730	response to heat
N39L_22960	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
N39L_22970	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N39L_22990	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
N39L_23030	COG2066	Belongs to the glutaminase family
N39L_23150	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
N39L_23170	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
N39L_23190	COG3240	lipase activity
N39L_23230	COG3536	Protein conserved in bacteria
N39L_23240	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
N39L_23250	COG0644	oxidoreductase
N39L_23290	COG1045	serine acetyltransferase
N39L_23650	COG0784	Response regulator, receiver
N39L_23720	COG0840	transmembrane signaling receptor activity
N39L_23730	COG0643	Histidine kinase
N39L_23730	COG0784	Response regulator, receiver
N39L_23730	COG2198	Histidine kinase
N39L_23850	COG3706	GGDEF domain
N39L_23850	COG4251	negative regulation of phosphorylation
N39L_23850	COG2203	Gaf domain
N39L_23850	COG5001	Diguanylate cyclase
N39L_23890	COG1943	Transposase
N39L_23910	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
N39L_23920	COG0424	maF-like protein
N39L_23990	COG0154	amidase activity
N39L_24010	COG1127	ABC transporter
N39L_24020	COG0391	Required for morphogenesis under gluconeogenic growth conditions
N39L_24040	COG3409	Peptidoglycan-binding domain 1 protein
N39L_24050	COG0612	Peptidase, M16
N39L_24080	COG0848	biopolymer transport protein
N39L_24090	COG0811	peptide transport
N39L_24100	COG1492	cobalamin metabolic process
N39L_24120	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
N39L_24180	COG0724	RNA recognition motif
N39L_24210	COG0737	Belongs to the 5'-nucleotidase family
N39L_24220	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
N39L_24230	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
N39L_24240	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
N39L_24260	COG0483	inositol monophosphate 1-phosphatase activity
N39L_24280	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
N39L_24290	COG0436	Aminotransferase
N39L_24300	COG3266	domain, Protein
N39L_24300	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
N39L_24320	COG0195	Participates in both transcription termination and antitermination
N39L_24330	COG0779	Required for maturation of 30S ribosomal subunits
N39L_24350	COG1216	Glycosyl transferase, family 2
N39L_24360	COG0360	Binds together with S18 to 16S ribosomal RNA
N39L_24390	COG1776	CheC inhibitor of MCP methylation
N39L_24400	COG2201	protein-glutamate methylesterase activity
N39L_24420	COG0446	pyridine nucleotide-disulphide oxidoreductase
N39L_24430	COG0579	oxidoreductase
N39L_24460	COG1108	ABC-type Mn2 Zn2 transport systems permease components
N39L_24470	COG1121	(ABC) transporter
N39L_24490	COG0557	exoribonuclease II activity
N39L_24500	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
N39L_24510	COG0267	Belongs to the bacterial ribosomal protein bL33 family
N39L_24540	COG0436	Aminotransferase
N39L_24550	COG3118	belongs to the thioredoxin family
N39L_24560	COG1494	fructose-1,6-bisphosphatase
N39L_24570	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
N39L_24580	COG0525	valine-tRNA ligase activity
N39L_24610	COG1672	PFAM Archaeal ATPase
N39L_24610	COG2319	Wd-40 repeat
N39L_24620	COG1672	PFAM Archaeal ATPase
N39L_24620	COG2319	Wd-40 repeat
N39L_24630	COG0009	L-threonylcarbamoyladenylate synthase
N39L_24640	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
N39L_24650	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
N39L_24660	COG1850	ribulose-bisphosphate carboxylase activity
N39L_24670	COG0235	Class ii aldolase
N39L_24700	COG0789	Transcriptional regulator
N39L_24710	COG2082	Precorrin-8x methylmutase
N39L_24730	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
N39L_24770	COG0444	Belongs to the ABC transporter superfamily
N39L_24780	COG4608	Belongs to the ABC transporter superfamily
N39L_24810	COG0657	acetylesterase activity
N39L_24830	COG3001	Fructosamine kinase
N39L_24850	COG2949	membrane
N39L_24860	COG0157	Belongs to the NadC ModD family
N39L_24880	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
N39L_24890	COG1216	Glycosyl transferase, family 2
N39L_24910	COG1132	(ABC) transporter
N39L_24920	COG0438	transferase activity, transferring glycosyl groups
N39L_24960	COG0438	transferase activity, transferring glycosyl groups
N39L_24980	COG1216	Glycosyl transferase, family 2
N39L_25000	COG0438	transferase activity, transferring glycosyl groups
N39L_25010	COG0438	transferase activity, transferring glycosyl groups
N39L_25070	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
N39L_25090	COG0515	serine threonine protein kinase
N39L_25090	COG1357	PFAM Pentapeptide repeats (8 copies)
N39L_25110	COG0784	Response regulator, receiver
N39L_25110	COG2205	protein histidine kinase activity
N39L_25130	COG3842	ATPase activity
N39L_25160	COG1653	transport
N39L_25170	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
N39L_25180	COG2076	Multidrug Resistance protein
N39L_25210	COG0515	serine threonine protein kinase
N39L_25210	COG1357	PFAM Pentapeptide repeats (8 copies)
N39L_25220	COG0515	serine threonine protein kinase
N39L_25220	COG1357	PFAM Pentapeptide repeats (8 copies)
N39L_25260	COG1252	NADH dehydrogenase
N39L_25280	COG0802	atpase or kinase
N39L_25300	COG1136	(ABC) transporter
N39L_25340	COG0713	ATP synthesis coupled electron transport
N39L_25360	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
N39L_25370	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
N39L_25380	COG0372	Belongs to the citrate synthase family
N39L_25390	COG2062	phosphohistidine phosphatase, SixA
N39L_25410	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
N39L_25430	COG0612	Peptidase, M16
N39L_25550	COG0135	phosphoribosylanthranilate isomerase activity
N39L_25580	COG0358	DNA primase activity
N39L_25600	COG2319	Wd-40 repeat
N39L_25600	COG4249	Peptidase C14 caspase catalytic subunit p20
N39L_25620	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
N39L_25660	COG1215	transferase activity, transferring glycosyl groups
N39L_25680	COG0347	Belongs to the P(II) protein family
N39L_25900	COG2270	Major facilitator Superfamily
N39L_25920	COG0635	Involved in the biosynthesis of porphyrin-containing compound
N39L_25940	COG2203	Gaf domain
N39L_25940	COG3706	GGDEF domain
N39L_25940	COG5001	Diguanylate cyclase
N39L_25940	COG4251	negative regulation of phosphorylation
N39L_25960	COG0745	RESPONSE REGULATOR receiver
N39L_25990	COG0745	RESPONSE REGULATOR receiver
N39L_26000	COG2205	protein histidine kinase activity
N39L_26000	COG2202	Pas domain
N39L_26020	COG3447	MASE1 domain protein
N39L_26020	COG5001	Diguanylate cyclase
N39L_26020	COG5002	protein histidine kinase activity
N39L_26090	COG0589	response to stress
N39L_26100	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
N39L_26110	COG0268	Binds directly to 16S ribosomal RNA
N39L_26120	COG0084	hydrolase, TatD family'
N39L_26130	COG0085	RNA polymerase activity
N39L_26140	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
N39L_26150	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
N39L_26380	COG2211	Major facilitator Superfamily
N39L_26410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N39L_26420	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
N39L_26470	COG0628	permease
N39L_26510	COG0463	Glycosyl transferase, family 2
N39L_26510	COG0457	Tetratricopeptide repeat
N39L_26530	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
N39L_26540	COG0589	response to stress
N39L_26550	COG0824	Thioesterase
N39L_26560	COG3852	Histidine kinase
N39L_26580	COG3300	MHYT domain
N39L_26580	COG5001	Diguanylate cyclase
N39L_26600	COG3706	GGDEF domain
N39L_26600	COG4251	negative regulation of phosphorylation
N39L_26600	COG5001	Diguanylate cyclase
N39L_26600	COG2203	Gaf domain
N39L_26640	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
N39L_26650	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
N39L_26650	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
N39L_26680	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
N39L_26700	COG4279	zinc finger
N39L_26760	COG1116	anion transmembrane transporter activity
N39L_26760	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
N39L_26770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N39L_26780	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
N39L_26780	COG1116	anion transmembrane transporter activity
N39L_26800	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
N39L_26870	COG0799	negative regulation of ribosome biogenesis
N39L_26880	COG0297	glycogen (starch) synthase activity
N39L_26900	COG1090	epimerase
N39L_26910	COG1160	GTP binding
N39L_26950	COG2205	protein histidine kinase activity
N39L_26950	COG3437	response regulator, receiver
N39L_26950	COG3850	Histidine kinase
N39L_26950	COG4999	Histidine kinase
N39L_26970	COG1028	Short-chain dehydrogenase reductase Sdr
N39L_27090	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N39L_27110	COG0525	valine-tRNA ligase activity
N39L_27120	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
N39L_27290	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
N39L_27580	COG0159	tryptophan synthase activity
N39L_27590	COG0656	L-ascorbic acid biosynthetic process
N39L_27680	COG0450	alkyl hydroperoxide reductase
N39L_27690	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
N39L_27720	COG0463	Glycosyl transferase, family 2
N39L_27720	COG1216	Glycosyl transferase, family 2
N39L_27740	COG1215	transferase activity, transferring glycosyl groups
N39L_27750	COG0542	response to heat
N39L_27760	COG0346	lactoylglutathione lyase activity
N39L_27830	COG1473	amidohydrolase
N39L_28380	COG1234	tRNA 3'-trailer cleavage
N39L_28400	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
N39L_28410	COG0436	Aminotransferase
N39L_28420	COG1619	proteins homologs of microcin C7 resistance protein MccF
N39L_28430	COG0384	phenazine biosynthesis protein PhzF
N39L_28440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
N39L_28780	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
N39L_28790	COG0829	nickel cation binding
N39L_28800	COG0831	urea catabolic process
N39L_28810	COG0832	Belongs to the urease beta subunit family
N39L_28820	COG0804	urea catabolic process
N39L_28830	COG3706	GGDEF domain
N39L_28870	COG1649	PFAM Uncharacterised BCR, COG1649
N39L_28890	COG1301	dicarboxylic acid transport
N39L_28900	COG1794	racemase activity, acting on amino acids and derivatives
N39L_29000	COG0516	GMP reductase activity
N39L_29010	COG3118	belongs to the thioredoxin family
N39L_29030	COG0745	RESPONSE REGULATOR receiver
N39L_29040	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
N39L_29110	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N39L_29140	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
N39L_29150	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
N39L_29150	COG0140	phosphoribosyl-ATP diphosphatase activity
N39L_29200	COG2308	Evidence 4 Homologs of previously reported genes of
N39L_29220	COG0540	Belongs to the ATCase OTCase family
N39L_29260	COG1132	(ABC) transporter
N39L_29290	COG0443	Heat shock 70 kDa protein
N39L_29330	COG0800	Aldolase
N39L_29340	COG0435	Glutathione S-transferase
N39L_29380	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
N39L_29390	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
N39L_29410	COG1691	(AIR) carboxylase
N39L_29820	COG0527	aspartate kinase activity
N39L_29830	COG0701	Predicted permease
N39L_29870	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
N39L_29900	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N39L_29920	COG0745	RESPONSE REGULATOR receiver
N39L_29930	COG2201	protein-glutamate methylesterase activity
N39L_29940	COG0643	Histidine kinase
N39L_29940	COG0784	Response regulator, receiver
N39L_29940	COG2198	Histidine kinase
N39L_29950	COG5278	phosphoserine phosphatase activity
N39L_29950	COG0840	transmembrane signaling receptor activity
N39L_29990	COG3854	ATPases associated with a variety of cellular activities
N39L_30020	COG1615	UPF0182 protein
N39L_30080	COG0438	transferase activity, transferring glycosyl groups
N39L_30080	COG1216	Glycosyl transferase, family 2
N39L_30200	COG0434	BtpA family
N39L_30210	COG4243	Vitamin k epoxide reductase
N39L_30240	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
N39L_30270	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
N39L_30280	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
N39L_30290	COG0750	zinc metalloprotease
N39L_30300	COG3769	mannosylglycerate metabolic process
N39L_30330	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
N39L_30370	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
N39L_30390	COG0443	Heat shock 70 kDa protein
N39L_30400	COG0355	proton-transporting ATP synthase activity, rotational mechanism
N39L_30410	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
N39L_30420	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
N39L_30440	COG2337	Toxic component of a toxin-antitoxin (TA) module
N39L_30490	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
N39L_30500	COG2894	cell division
N39L_30510	COG0850	regulation of cytokinetic process
N39L_30540	COG4953	penicillin-binding protein 1C
N39L_30550	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
N39L_30570	COG0745	RESPONSE REGULATOR receiver
N39L_30700	COG3335	DDE superfamily endonuclease
N39L_30840	COG0640	Transcriptional regulator
N39L_30880	COG1216	Glycosyl transferase, family 2
N39L_30930	COG2274	protein secretion by the type I secretion system
N39L_31060	COG0438	transferase activity, transferring glycosyl groups
N39L_31070	COG0371	Dehydrogenase
N39L_31080	COG0436	Aminotransferase
N39L_31100	COG0189	ligase activity
N39L_31170	COG2205	protein histidine kinase activity
N39L_31200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N39L_31240	COG4243	Vitamin k epoxide reductase
N39L_31250	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
N39L_31260	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
N39L_31400	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
N39L_31410	COG1704	LemA family
N39L_31430	COG0312	modulator of DNA gyrase
N39L_31480	COG5002	protein histidine kinase activity
N39L_31530	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
N39L_31590	COG0095	Lipoate-protein ligase
N39L_31600	COG1994	Peptidase M50
N39L_31600	COG0517	IMP dehydrogenase activity
N39L_31630	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
N39L_31630	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
N39L_31740	COG2326	polyphosphate kinase activity
N39L_31770	COG4172	Belongs to the ABC transporter superfamily
N39L_31780	COG0284	orotidine-5'-phosphate decarboxylase activity
N39L_31790	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
N39L_31810	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
N39L_31870	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
N39L_31920	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
N39L_31940	COG0589	response to stress
N39L_31950	COG0126	phosphoglycerate kinase activity
N39L_31960	COG0784	Response regulator, receiver
N39L_31960	COG2205	protein histidine kinase activity
N39L_31980	COG0493	'glutamate synthase
N39L_32020	COG0463	Glycosyl transferase, family 2
N39L_32030	COG2201	protein-glutamate methylesterase activity
N39L_32050	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N39L_32160	COG0175	sulfate reduction
N39L_32180	COG1525	nuclease
N39L_32210	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
N39L_32240	COG2205	protein histidine kinase activity
N39L_32240	COG0784	Response regulator, receiver
N39L_32250	COG0488	(ABC) transporter
N39L_32300	COG2226	methyltransferase
N39L_32310	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N39L_32320	COG5001	Diguanylate cyclase
N39L_32320	COG4251	negative regulation of phosphorylation
N39L_32320	COG3706	GGDEF domain
N39L_32320	COG2203	Gaf domain
N39L_32380	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
N39L_32420	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
N39L_32420	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
N39L_32460	COG0251	oxidation-reduction process
N39L_32470	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
N39L_32480	COG0058	SHG alpha-glucan phosphorylase activity
N39L_32490	COG0419	ATPase involved in DNA repair
N39L_32500	COG1597	lipid kinase activity
N39L_32530	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
N39L_32540	COG0564	pseudouridine synthase activity
N39L_32560	COG1136	(ABC) transporter
N39L_32560	COG0577	efflux transmembrane transporter activity
N39L_32630	COG2205	protein histidine kinase activity
N39L_32660	COG0788	formyltetrahydrofolate deformylase activity
N39L_33010	COG3335	DDE superfamily endonuclease
N39L_33140	COG0515	serine threonine protein kinase
N39L_33140	COG1357	PFAM Pentapeptide repeats (8 copies)
N39L_33160	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
N39L_33170	COG1376	ErfK ybiS ycfS ynhG family protein
N39L_33190	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
N39L_33210	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
N39L_33220	COG0668	transmembrane transport
N39L_33250	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
N39L_33250	COG3264	Mechanosensitive ion channel
N39L_33270	COG0217	transcriptional regulatory protein
N39L_33290	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
N39L_33320	COG2815	serine threonine protein kinase
N39L_33320	COG0515	serine threonine protein kinase
N39L_33330	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N39L_33340	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
N39L_33360	COG0330	HflC and HflK could
N39L_33410	COG3842	ATPase activity
N39L_33740	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
N39L_33940	COG3239	Fatty acid desaturase
N39L_33960	COG3842	ATPase activity
N39L_33970	COG4597	amino acid ABC transporter
N39L_33980	COG0765	amino acid transport
N39L_34000	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
N39L_34050	COG0167	dihydroorotate dehydrogenase activity
N39L_34060	COG0497	DNA recombination
N39L_34090	COG1518	maintenance of DNA repeat elements
N39L_34200	COG0515	serine threonine protein kinase
N39L_34200	COG2815	serine threonine protein kinase
N39L_34380	COG1332	CRISPR-associated RAMP protein, Csm5 family
N39L_34400	COG1337	RAMP superfamily
N39L_34480	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
N39L_34490	COG0534	Mate efflux family protein
N39L_34500	COG0556	nucleotide-excision repair
N39L_34510	COG0123	including yeast histone deacetylase and acetoin utilization protein
N39L_34520	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
N39L_34540	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
N39L_34550	COG0163	prenyltransferase activity
N39L_34570	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
N39L_34580	COG0514	ATP-dependent DNA helicase (RecQ)
N39L_34600	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
N39L_34650	COG0193	aminoacyl-tRNA hydrolase activity
N39L_34660	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
N39L_34690	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
N39L_34700	COG1234	tRNA 3'-trailer cleavage
N39L_34740	COG0745	RESPONSE REGULATOR receiver
N39L_34760	COG3659	wide pore channel activity
N39L_34770	COG3266	domain, Protein
N39L_34770	COG0515	serine threonine protein kinase
N39L_34810	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
N39L_34830	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
N39L_34830	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
N39L_34860	COG1132	(ABC) transporter
N39L_34890	COG1028	Short-chain dehydrogenase reductase Sdr
N39L_35000	COG0484	heat shock protein binding
N39L_35010	COG0740	serine-type endopeptidase activity
N39L_35020	COG0740	serine-type endopeptidase activity
N39L_35030	COG0740	serine-type endopeptidase activity
N39L_35040	COG2304	oxidoreductase activity
N39L_35050	COG0194	GDP metabolic process
N39L_35060	COG2052	Domain of unknown function (DUF370)
N39L_35750	COG1357	PFAM Pentapeptide repeats (8 copies)
N39L_35750	COG0515	serine threonine protein kinase
N39L_35760	COG0616	signal peptide processing
N39L_35770	COG0724	RNA recognition motif
N39L_35810	COG0438	transferase activity, transferring glycosyl groups
N39L_35810	COG1216	Glycosyl transferase, family 2
N39L_35940	COG0204	Acyl-transferase
N39L_36000	COG0436	Aminotransferase
N39L_36020	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
N39L_36030	COG1530	ribonuclease E activity
N39L_36040	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
N39L_36070	COG0077	Prephenate dehydratase
N39L_36070	COG1605	Chorismate mutase
N39L_36080	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
N39L_36140	COG0316	Belongs to the HesB IscA family
N39L_36170	COG0067	glutamate synthase
N39L_36170	COG0070	glutamate synthase
N39L_36170	COG0069	glutamate synthase activity
N39L_36320	COG1475	DNA binding
N39L_36330	COG1716	ATPase activity
N39L_36330	COG1131	(ABC) transporter
N39L_36330	COG0842	Transport permease protein
N39L_36340	COG3266	domain, Protein
N39L_36340	COG0515	serine threonine protein kinase
N39L_36420	COG1587	Uroporphyrinogen-III synthase
N39L_36450	COG2010	Cytochrome c
N39L_36470	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
N39L_36500	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
N39L_36540	COG1216	Glycosyl transferase, family 2
N39L_36550	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N39L_36570	COG3850	Histidine kinase
N39L_36570	COG3437	response regulator, receiver
N39L_36570	COG2205	protein histidine kinase activity
N39L_36570	COG4999	Histidine kinase
N39L_36590	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
N39L_36700	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
N39L_36740	COG2010	Cytochrome c
N39L_36820	COG0617	tRNA 3'-terminal CCA addition
N39L_36890	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
N39L_36890	COG4451	ribulose bisphosphate carboxylase, small
N39L_36910	COG0181	hydroxymethylbilane synthase activity
N39L_37580	COG1132	(ABC) transporter
N39L_37590	COG2319	Wd-40 repeat
N39L_37590	COG1672	PFAM Archaeal ATPase
N39L_37620	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
N39L_37630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N39L_37630	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
N39L_37690	COG0830	nickel cation binding
N39L_37700	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
N39L_37710	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
N39L_37720	COG2226	methyltransferase
N39L_37750	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
N39L_37760	COG1716	ATPase activity
N39L_37760	COG1131	(ABC) transporter
N39L_37760	COG0842	Transport permease protein
N39L_37780	COG0363	glucosamine-6-phosphate deaminase activity
N39L_37790	COG1716	ATPase activity
N39L_37850	COG2886	Uncharacterised protein family (UPF0175)
N39L_38360	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
N39L_38380	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
N39L_38390	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
N39L_38400	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
N39L_38550	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
N39L_39040	COG0454	-acetyltransferase
N39L_39130	COG1247	-acetyltransferase
N39L_39140	COG0297	glycogen (starch) synthase activity
N39L_39160	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N39L_39180	COG0028	Belongs to the TPP enzyme family
N39L_39200	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
N39L_39220	COG2267	carboxylic ester hydrolase activity
N39L_39230	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
N39L_39240	COG1331	Highly conserved protein containing a thioredoxin domain
N39L_39280	COG4251	negative regulation of phosphorylation
N39L_39290	COG4783	chaperone-mediated protein folding
N39L_39300	COG2200	EAL domain
N39L_39300	COG2199	diguanylate cyclase activity
N39L_39430	COG1598	PFAM Uncharacterised protein family UPF0150
N39L_39580	COG1252	NADH dehydrogenase
N39L_39610	COG2264	protein methyltransferase activity
N39L_39620	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
N39L_39690	COG0515	serine threonine protein kinase
N39L_39690	COG1357	PFAM Pentapeptide repeats (8 copies)
N39L_39740	COG1714	RDD family
N39L_39800	COG2091	lysine biosynthetic process via aminoadipic acid
N39L_39830	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
N39L_39840	COG0006	proline dipeptidase activity
N39L_39870	COG4451	ribulose bisphosphate carboxylase, small
N39L_39890	COG1850	ribulose-bisphosphate carboxylase activity
N39L_39900	COG0583	DNA-binding transcription factor activity
N39L_39950	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
N39L_39990	COG0484	heat shock protein binding
N39L_40090	COG4636	protein conserved in cyanobacteria
N39L_40110	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
N39L_40130	COG5635	Nacht domain
N39L_40130	COG2319	Wd-40 repeat
N39L_40140	COG1748	Saccharopine dehydrogenase
N39L_40160	COG0629	single-stranded DNA binding
N39L_40190	COG2226	methyltransferase
N39L_40200	COG4399	Belongs to the UPF0754 family
N39L_40210	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
N39L_40220	COG1160	GTP binding
N39L_40230	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
N39L_40250	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
N39L_40260	COG1799	cell septum assembly
N39L_40270	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
N39L_40280	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
N39L_40300	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
N39L_40330	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
N39L_40330	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
N39L_40370	COG4245	von Willebrand factor, type A
N39L_40400	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
N39L_40400	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
N39L_40420	COG0515	serine threonine protein kinase
N39L_40470	COG1450	Type ii and iii secretion system protein
N39L_40480	COG0776	regulation of translation
N39L_40490	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
N39L_40510	COG0322	excinuclease ABC activity
N39L_40520	COG2124	cytochrome p450
N39L_40550	COG1819	glycosyl
N39L_40580	COG0142	geranyltranstransferase activity
N39L_40620	COG0579	oxidoreductase
N39L_40630	COG0004	ammonium transporteR
N39L_40670	COG0501	Belongs to the peptidase M48B family
N39L_40680	COG1704	LemA family
N39L_40690	COG3977	Valine--pyruvate aminotransferase
N39L_40730	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
N39L_40800	COG2239	Acts as a magnesium transporter
N39L_40810	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
N39L_40830	COG2319	Wd-40 repeat
N39L_40830	COG3903	Transcriptional regulator
N39L_40880	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
N39L_40890	COG0515	serine threonine protein kinase
N39L_40890	COG3266	domain, Protein
N39L_40900	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
N39L_40910	COG1834	amidinotransferase
N39L_40970	COG1166	arginine decarboxylase activity
N39L_40980	COG1210	Utp--glucose-1-phosphate uridylyltransferase
N39L_40990	COG1640	4-alpha-glucanotransferase
N39L_41010	COG1640	4-alpha-glucanotransferase
N39L_41060	COG1357	PFAM Pentapeptide repeats (8 copies)
N39L_41060	COG0515	serine threonine protein kinase
N39L_41100	COG0745	RESPONSE REGULATOR receiver
N39L_41110	COG2197	response regulator
N39L_41130	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
N39L_41170	COG1487	ribonuclease activity
N39L_41200	COG0518	GMP synthase (glutamine-hydrolyzing) activity
N39L_41200	COG0519	Catalyzes the synthesis of GMP from XMP
N39L_41240	COG1104	cysteine desulfurase activity
N39L_41390	COG1104	cysteine desulfurase activity
N39L_41410	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
N39L_41420	COG0805	protein transport
N39L_41450	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
N39L_41470	COG1216	Glycosyl transferase, family 2
N39L_41490	COG0827	DNA restriction-modification system
N39L_41500	COG0270	DNA (cytosine-5-)-methyltransferase activity
N39L_41510	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
N39L_41520	COG2203	Gaf domain
N39L_41520	COG3706	GGDEF domain
N39L_41520	COG4251	negative regulation of phosphorylation
N39L_41520	COG5001	Diguanylate cyclase
N39L_41530	COG1187	pseudouridine synthase activity
N39L_41570	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
N39L_41590	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
N39L_41610	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
N39L_41610	COG4451	ribulose bisphosphate carboxylase, small
N39L_41620	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
N39L_41630	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
N39L_41640	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
N39L_41650	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
N39L_41660	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
N39L_41680	COG1132	(ABC) transporter
N39L_41720	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
N39L_41760	COG3842	ATPase activity
N39L_41780	COG1176	ABC-type spermidine putrescine transport system, permease component I
N39L_41790	COG1177	transmembrane transport
N39L_41800	COG0196	riboflavin kinase activity
N39L_41820	COG0714	Associated with various cellular activities
N39L_41840	COG1959	2 iron, 2 sulfur cluster binding
N39L_41850	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
N39L_41860	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
N39L_41870	COG1304	FMN binding
N39L_41900	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
N39L_41910	COG0227	Belongs to the bacterial ribosomal protein bL28 family
N39L_41920	COG1754	DNA topoisomerase type I activity
N39L_41920	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
N39L_41940	COG0612	Peptidase, M16
N39L_41950	COG0390	transport system, permease component
N39L_42000	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
N39L_42010	COG0187	DNA topoisomerase II activity
N39L_42010	COG1372	Participates in initiation and elongation during chromosome replication
N39L_42030	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
N39L_42040	COG0740	serine-type endopeptidase activity
N39L_42050	COG0544	peptidyl-prolyl cis-trans isomerase activity
N39L_42060	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
N39L_42070	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N39L_42080	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
N39L_42090	COG3829	transcription factor binding
N39L_42090	COG3290	protein histidine kinase activity
N39L_42120	COG4948	Mandelate Racemase Muconate Lactonizing
N39L_42140	COG1192	Involved in chromosome partitioning
N39L_42150	COG0596	Alpha beta hydrolase
N39L_42180	COG5001	Diguanylate cyclase
N39L_42180	COG3300	MHYT domain
N39L_42190	COG2239	Acts as a magnesium transporter
N39L_42300	COG1185	polyribonucleotide nucleotidyltransferase activity
N39L_42310	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
N39L_42320	COG0183	Belongs to the thiolase family
N39L_42330	COG1028	Short-chain dehydrogenase reductase Sdr
N39L_42390	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
N39L_42410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N39L_42410	COG2022	thiamine diphosphate biosynthetic process
N39L_42610	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
N39L_42650	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
N39L_42660	COG1122	ATPase activity
N39L_42670	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
N39L_42690	COG0515	serine threonine protein kinase
N39L_42690	COG1357	PFAM Pentapeptide repeats (8 copies)
N39L_42700	COG1064	alcohol dehydrogenase
N39L_42710	COG1012	belongs to the aldehyde dehydrogenase family
N39L_42710	COG1454	alcohol dehydrogenase
N39L_42720	COG2319	Wd-40 repeat
N39L_42720	COG3903	Transcriptional regulator
N39L_42750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N39L_42800	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
N39L_42830	COG1950	PFAM Membrane protein of
N39L_42860	COG1410	methionine synthase
N39L_42860	COG0646	methionine synthase
N39L_42870	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
N39L_42880	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
N39L_42890	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
N39L_42900	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
N39L_42910	COG3906	Belongs to the UPF0473 family
N39L_42920	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
N39L_43000	COG0261	This protein binds to 23S rRNA in the presence of protein L20
N39L_43020	COG0211	Belongs to the bacterial ribosomal protein bL27 family
N39L_43050	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
N39L_43060	COG4251	negative regulation of phosphorylation
N39L_43110	COG5001	Diguanylate cyclase
N39L_43110	COG3706	GGDEF domain
N39L_43110	COG2203	Gaf domain
N39L_43110	COG4251	negative regulation of phosphorylation
N39L_43120	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
N39L_43170	COG1293	RNA-binding protein homologous to eukaryotic snRNP
N39L_43180	COG1902	pentaerythritol trinitrate reductase activity
N39L_43220	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N39L_43230	COG0431	NADPH-dependent FMN reductase
N39L_43240	COG0798	PFAM Bile acid sodium symporter
N39L_43450	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
N39L_43490	COG1940	carbohydrate kinase activity
N39L_43500	COG2211	Major facilitator Superfamily
N39L_43590	COG0723	plastoquinol--plastocyanin reductase activity
N39L_43600	COG3258	Cytochrome c
N39L_43750	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
N39L_43770	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
N39L_43850	COG0003	Pfam Anion-transporting ATPase
N39L_44040	COG1185	polyribonucleotide nucleotidyltransferase activity
N39L_44070	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
N39L_44080	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
N39L_44130	COG0741	lytic transglycosylase activity
N39L_44160	COG0191	fructose-bisphosphate aldolase activity
N39L_44170	COG0676	glucose-6-phosphate 1-epimerase activity
N39L_44180	COG2843	Capsule synthesis protein
N39L_44200	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
N39L_44230	COG3751	2OG-Fe(II) oxygenase superfamily
N39L_44240	COG3751	2OG-Fe(II) oxygenase superfamily
N39L_44330	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
N39L_44340	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
N39L_44380	COG2211	Major facilitator Superfamily
N39L_44410	COG4191	Histidine kinase
N39L_44440	COG0640	Transcriptional regulator
N39L_44520	COG0515	serine threonine protein kinase
N39L_44520	COG1357	PFAM Pentapeptide repeats (8 copies)
N39L_44530	COG1357	PFAM Pentapeptide repeats (8 copies)
N39L_44530	COG0515	serine threonine protein kinase
N39L_44540	COG0515	serine threonine protein kinase
N39L_44540	COG1357	PFAM Pentapeptide repeats (8 copies)
N39L_44550	COG1357	PFAM Pentapeptide repeats (8 copies)
N39L_44550	COG0515	serine threonine protein kinase
N39L_44560	COG0415	Belongs to the DNA photolyase family
N39L_44570	COG0494	nUDIX hydrolase
N39L_44580	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
N39L_44600	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
N39L_44620	COG1192	Involved in chromosome partitioning
N39L_44640	COG2373	Large extracellular alpha-helical protein
N39L_44650	COG0837	glucose binding
N39L_44660	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
N39L_44670	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
N39L_44680	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
N39L_44690	COG0484	heat shock protein binding
N39L_44720	COG1606	tRNA processing
N39L_44750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N39L_44770	COG0170	dolichyl monophosphate biosynthetic process
N39L_44970	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
N39L_44980	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
N39L_44990	COG0668	transmembrane transport
N39L_45280	COG1131	(ABC) transporter
N39L_45330	COG2202	Pas domain
N39L_45330	COG2205	protein histidine kinase activity
N39L_45340	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
N39L_45350	COG1234	tRNA 3'-trailer cleavage
N39L_45440	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
N39L_45460	COG4245	von Willebrand factor, type A
N39L_45530	COG3259	Nickel-dependent hydrogenase
N39L_45540	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
N39L_45560	COG1151	hydroxylamine reductase activity
N39L_45580	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
N39L_45590	COG0298	carbon dioxide binding
N39L_45600	COG0674	pyruvate-flavodoxin oxidoreductase activity
N39L_45600	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
N39L_45600	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
N39L_45600	COG1013	pyruvate-flavodoxin oxidoreductase activity
N39L_45610	COG0167	dihydroorotate dehydrogenase activity
N39L_45630	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
N39L_45680	COG0828	Belongs to the bacterial ribosomal protein bS21 family
N39L_45690	COG2205	protein histidine kinase activity
N39L_45800	COG0542	response to heat
N39L_45870	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
N39L_45880	COG0457	Tetratricopeptide repeat
N39L_45950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N39L_45950	COG2205	protein histidine kinase activity
N39L_45970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N39L_45980	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
N39L_45990	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
N39L_46000	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
N39L_46010	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
N39L_46050	COG2340	Cysteine-rich secretory protein family
N39L_46330	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
N39L_46340	COG0297	glycogen (starch) synthase activity
N39L_46520	COG1162	GTPase activity
N39L_46570	COG0445	tRNA wobble uridine modification
N39L_46600	COG1215	transferase activity, transferring glycosyl groups
N39L_46850	COG1028	Short-chain dehydrogenase reductase Sdr
N39L_46870	COG1305	Transglutaminase-like
N39L_46900	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
N39L_46920	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
N39L_46950	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
N39L_46970	COG2205	protein histidine kinase activity
N39L_46970	COG0784	Response regulator, receiver
N39L_46980	COG4191	Histidine kinase
N39L_46990	COG0180	Tryptophanyl-tRNA synthetase
N39L_47060	COG4999	Histidine kinase
N39L_47060	COG3850	Histidine kinase
N39L_47060	COG3437	response regulator, receiver
N39L_47060	COG2205	protein histidine kinase activity
N39L_47070	COG0492	ferredoxin-NADP+ reductase activity
N39L_47090	COG1028	Short-chain dehydrogenase reductase Sdr
N39L_47100	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
N39L_47120	COG4636	protein conserved in cyanobacteria
N39L_47130	COG4636	protein conserved in cyanobacteria
N39L_47210	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
N39L_47250	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N39L_47270	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N39L_47280	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N39L_47310	COG0024	Methionine aminopeptidase
N39L_47320	COG0745	RESPONSE REGULATOR receiver
N39L_47370	COG3757	hydrolase, family 25
N39L_47380	COG2226	methyltransferase
N39L_47390	COG0492	ferredoxin-NADP+ reductase activity
N39L_47410	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
N39L_47420	COG1012	belongs to the aldehyde dehydrogenase family
N39L_47440	COG0179	Fumarylacetoacetate (FAA) hydrolase
N39L_47450	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
N39L_47460	COG0518	GMP synthase (glutamine-hydrolyzing) activity
N39L_47460	COG0519	Catalyzes the synthesis of GMP from XMP
N39L_47490	COG2239	Acts as a magnesium transporter
N39L_47510	COG1285	pathogenesis
N39L_47520	COG0366	Alpha amylase catalytic
N39L_47530	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
N39L_47550	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
N39L_47590	COG0745	RESPONSE REGULATOR receiver
N39L_47620	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
N39L_47630	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
N39L_47640	COG1546	Belongs to the CinA family
N39L_47640	COG1058	Belongs to the CinA family
N39L_47660	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
N39L_47730	COG1480	7TM receptor with intracellular HD hydrolase
N39L_47750	COG0495	leucyl-tRNA aminoacylation
N39L_47790	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
N39L_47820	COG0564	pseudouridine synthase activity
N39L_47890	COG0116	Belongs to the methyltransferase superfamily
N39L_47910	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
N39L_47980	COG0123	including yeast histone deacetylase and acetoin utilization protein
N39L_48010	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
N39L_48020	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
N39L_48340	COG0450	alkyl hydroperoxide reductase
N39L_48350	COG2133	pyrroloquinoline quinone binding
N39L_48390	COG2267	carboxylic ester hydrolase activity
N39L_48400	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
N39L_48430	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
N39L_48440	COG3842	ATPase activity
N39L_48450	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
N39L_48470	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
N39L_48480	COG3437	response regulator, receiver
N39L_48480	COG2205	protein histidine kinase activity
N39L_48480	COG4999	Histidine kinase
N39L_48480	COG3850	Histidine kinase
N39L_48500	COG2205	protein histidine kinase activity
N39L_48530	COG0504	CTP synthase activity
N39L_48540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N39L_48570	COG0653	protein targeting
N39L_48590	COG1715	Restriction endonuclease
N39L_48670	COG0024	Methionine aminopeptidase
N39L_48930	COG2202	Pas domain
N39L_48930	COG3920	Histidine kinase
N39L_48940	COG0673	inositol 2-dehydrogenase activity
N39L_49090	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
N39L_49110	COG0039	L-malate dehydrogenase activity
N39L_49130	COG1357	PFAM Pentapeptide repeats (8 copies)
N39L_49130	COG0515	serine threonine protein kinase
N39L_49270	COG0820	rRNA (adenine-C2-)-methyltransferase activity
N39L_49290	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
N39L_49360	COG1487	ribonuclease activity
N39L_49380	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
N39L_49380	COG3264	Mechanosensitive ion channel
N39L_49390	COG4208	sulfate ABC transporter
N39L_49400	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
N39L_49410	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
N39L_49430	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
N39L_49450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N39L_49460	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
N39L_49470	COG1045	serine acetyltransferase
N39L_49480	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N39L_49490	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
N39L_49500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N39L_49510	COG1042	CoA-binding domain protein
N39L_49510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N39L_49510	COG0045	succinate-CoA ligase (ADP-forming) activity
N39L_49520	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
N39L_49540	COG2911	Protein conserved in bacteria
N39L_49540	COG3266	domain, Protein
N39L_49540	COG1361	Conserved repeat domain
N39L_49550	COG2226	methyltransferase
N39L_49570	COG0058	SHG alpha-glucan phosphorylase activity
N39L_49590	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
N39L_49630	COG3621	Patatin-like phospholipase
N39L_49670	COG2226	methyltransferase
N39L_49810	COG3266	domain, Protein
N39L_49810	COG0515	serine threonine protein kinase
N39L_49830	COG0515	serine threonine protein kinase
N39L_49870	COG1122	ATPase activity
N39L_49890	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
N39L_49900	COG0310	cobalt ion transport
N39L_49910	COG1216	Glycosyl transferase, family 2
N39L_49920	COG0137	argininosuccinate synthase activity
N39L_49930	COG5322	oxidoreductase activity
N39L_49950	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
N39L_49960	COG0395	ABC-type sugar transport system, permease component
N39L_49980	COG0438	transferase activity, transferring glycosyl groups
N39L_49980	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
N39L_50000	COG1012	belongs to the aldehyde dehydrogenase family
N39L_50000	COG1454	alcohol dehydrogenase
N39L_50010	COG0651	ATP synthesis coupled electron transport
N39L_50020	COG1006	Multisubunit Na H antiporter MnhC subunit
N39L_50030	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
N39L_50090	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
N39L_50130	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
N39L_50140	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
N39L_50150	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
N39L_50170	COG0784	Response regulator, receiver
N39L_50170	COG2205	protein histidine kinase activity
N39L_50170	COG5002	protein histidine kinase activity
N39L_50250	COG0189	ligase activity
N39L_50250	COG4067	protein conserved in archaea
N39L_50280	COG1176	ABC-type spermidine putrescine transport system, permease component I
N39L_50300	COG1177	transmembrane transport
N39L_50320	COG0469	pyruvate kinase activity
N39L_50330	COG1372	Participates in initiation and elongation during chromosome replication
N39L_50330	COG0305	Participates in initiation and elongation during chromosome replication
N39L_50340	COG0359	binds to the 23S rRNA
N39L_50350	COG1126	abc transporter atp-binding protein
N39L_50380	COG1131	(ABC) transporter
N39L_50390	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
N39L_50420	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
N39L_50430	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
N39L_50480	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
N39L_50500	COG2252	PERMEase
N39L_50510	COG2203	Gaf domain
N39L_50520	COG0628	permease
N39L_50530	COG0697	spore germination
N39L_50540	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N39L_50550	COG0302	gtp cyclohydrolase
N39L_50560	COG1028	Short-chain dehydrogenase reductase Sdr
N39L_50570	COG0825	malonyl-CoA metabolic process
N39L_50590	COG0678	peroxiredoxin activity
N39L_50600	COG0515	serine threonine protein kinase
N39L_50600	COG1357	PFAM Pentapeptide repeats (8 copies)
N39L_50650	COG3937	granule-associated protein
N39L_50660	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
N39L_50670	COG0631	protein serine/threonine phosphatase activity
N39L_50680	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
N39L_50700	COG0513	Belongs to the DEAD box helicase family
N39L_50740	COG1070	Carbohydrate kinase
N39L_50750	COG3409	Peptidoglycan-binding domain 1 protein
N39L_50750	COG3773	Cell wall hydrolase
N39L_50760	COG0151	Belongs to the GarS family
N39L_50770	COG5002	protein histidine kinase activity
N39L_50850	COG0429	hydrolase of the alpha beta-hydrolase fold
N39L_50860	COG0515	serine threonine protein kinase
N39L_50860	COG1357	PFAM Pentapeptide repeats (8 copies)
N39L_50870	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
N39L_50920	COG0702	epimerase
N39L_51050	COG1132	(ABC) transporter
N39L_51070	COG0463	Glycosyl transferase, family 2
N39L_51080	COG3118	belongs to the thioredoxin family
N39L_51090	COG1028	Short-chain dehydrogenase reductase Sdr
N39L_51100	COG0459	protein refolding
N39L_51110	COG0745	RESPONSE REGULATOR receiver
N39L_51120	COG5002	protein histidine kinase activity
N39L_51160	COG0571	ribonuclease III activity
N39L_51170	COG4245	von Willebrand factor, type A
N39L_51210	COG5001	Diguanylate cyclase
N39L_51210	COG4251	negative regulation of phosphorylation
N39L_51210	COG3706	GGDEF domain
N39L_51210	COG2203	Gaf domain
N39L_51270	COG0142	geranyltranstransferase activity
N39L_51300	COG0602	queuosine metabolic process
N39L_51310	COG0023	Translation Initiation Factor
N39L_51380	COG1496	oxidoreductase activity
N39L_51390	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
N39L_51390	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
N39L_51400	COG0739	heme binding
N39L_51430	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N39L_51440	COG0745	RESPONSE REGULATOR receiver
N39L_51470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N39L_51540	COG2954	triphosphatase activity
N39L_51580	COG2197	response regulator
N39L_51600	COG0124	histidyl-tRNA synthetase
N39L_51620	COG2319	Wd-40 repeat
N39L_51620	COG4249	Peptidase C14 caspase catalytic subunit p20
N39L_51620	COG2319	Wd-40 repeat
N39L_51620	COG4249	Peptidase C14 caspase catalytic subunit p20
N39L_51650	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
N39L_51660	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
N39L_51680	COG4249	Peptidase C14 caspase catalytic subunit p20
N39L_51680	COG2319	Wd-40 repeat
N39L_51700	COG2205	protein histidine kinase activity
N39L_51730	COG0515	serine threonine protein kinase
N39L_51730	COG1357	PFAM Pentapeptide repeats (8 copies)
N39L_51740	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N39L_51740	COG0072	phenylalanine-tRNA ligase activity
N39L_51810	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
N39L_51920	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
N39L_51950	COG2027	D-alanyl-D-alanine carboxypeptidase
N39L_51970	COG0416	fatty acid biosynthetic process
N39L_51980	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N39L_51990	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
N39L_52000	COG5002	protein histidine kinase activity
N39L_52210	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
N39L_52230	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
N39L_52350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N39L_52470	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
N39L_53080	COG1116	anion transmembrane transporter activity
N39L_53090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
N39L_53090	COG1116	anion transmembrane transporter activity
N39L_53100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N39L_53120	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
N39L_53140	COG0542	response to heat
N39L_53160	COG0542	response to heat
N39L_53410	COG1404	Belongs to the peptidase S8 family
N39L_53500	COG0426	domain, Protein
N39L_53500	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N39L_53510	COG0426	domain, Protein
N39L_53510	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N39L_53530	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
N39L_53580	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
N39L_53590	COG0742	ribosomal rna small subunit methyltransferase
N39L_53600	COG3956	TIGRFAM MazG family protein
N39L_53660	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N39L_53690	COG0398	Pfam SNARE associated Golgi protein
N39L_53710	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
N39L_53740	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
N39L_53750	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
N39L_53760	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
N39L_53770	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
N39L_53780	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N39L_53820	COG0530	calcium, potassium:sodium antiporter activity
N39L_53830	COG0018	arginyl-trna synthetase
N39L_53870	COG5002	protein histidine kinase activity
N39L_53870	COG0784	Response regulator, receiver
N39L_53890	COG1490	D-aminoacyl-tRNA deacylase activity
N39L_53900	COG0523	cobalamin synthesis protein
N39L_53910	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
N39L_53970	COG0438	transferase activity, transferring glycosyl groups
N39L_54010	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
N39L_54110	COG0583	DNA-binding transcription factor activity
N39L_54590	COG0829	nickel cation binding
N39L_54600	COG0829	nickel cation binding
N39L_54630	COG0410	ABC transporter
N39L_54640	COG1129	ABC transporter
N39L_54660	COG0515	serine threonine protein kinase
N39L_54660	COG1357	PFAM Pentapeptide repeats (8 copies)
N39L_54680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N39L_54740	COG1115	amino acid carrier protein
N39L_54770	COG4249	Peptidase C14 caspase catalytic subunit p20
N39L_54770	COG2319	Wd-40 repeat
N39L_54820	COG0464	growth
N39L_54830	COG0515	serine threonine protein kinase
N39L_54840	COG0515	serine threonine protein kinase
N39L_54940	COG0515	serine threonine protein kinase
N39L_54950	COG0515	serine threonine protein kinase
N39L_54980	COG0443	Heat shock 70 kDa protein
N39L_55000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N39L_55030	COG0515	serine threonine protein kinase
N39L_55040	COG1845	cytochrome c oxidase, subunit III
N39L_55050	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
N39L_55080	COG0109	protoheme IX farnesyltransferase activity
N39L_55100	COG2203	Gaf domain
N39L_55100	COG3706	GGDEF domain
N39L_55100	COG4251	negative regulation of phosphorylation
N39L_55100	COG5001	Diguanylate cyclase
N39L_55110	COG4251	negative regulation of phosphorylation
N39L_55120	COG2198	Histidine kinase
N39L_55120	COG0784	Response regulator, receiver
N39L_55120	COG2205	protein histidine kinase activity
N39L_55130	COG2203	Gaf domain
N39L_55130	COG4251	negative regulation of phosphorylation
N39L_55130	COG3706	GGDEF domain
N39L_55130	COG5001	Diguanylate cyclase
N39L_55140	COG1672	PFAM Archaeal ATPase
N39L_55140	COG2319	Wd-40 repeat
N39L_55160	COG3659	wide pore channel activity
N39L_55230	COG0439	Biotin carboxylase
N39L_55560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N39L_55750	COG4585	Histidine kinase
N39L_55760	COG2197	response regulator
N39L_55830	COG1074	ATP-dependent DNA helicase activity
N39L_55850	COG3266	domain, Protein
N39L_55850	COG0515	serine threonine protein kinase
N39L_55860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N39L_55890	COG2217	Heavy metal translocating P-type atpase
N39L_55900	COG0505	Belongs to the CarA family
N39L_55920	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N39L_56050	COG4956	integral membrane protein (PIN domain superfamily)
N39L_56090	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
N39L_56100	COG0149	triose-phosphate isomerase activity
N39L_56170	COG0352	thiamine-phosphate diphosphorylase activity
N39L_56230	COG1088	dTDP-glucose 4,6-dehydratase activity
N39L_56250	COG2843	Capsule synthesis protein
N39L_56280	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N39L_56310	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
N39L_56310	COG1116	anion transmembrane transporter activity
N39L_56320	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
N39L_56340	COG4172	Belongs to the ABC transporter superfamily
N39L_56350	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
N39L_56360	COG0511	ligase activity, forming carbon-carbon bonds
N39L_56390	COG3608	succinylglutamate desuccinylase aspartoacylase
N39L_56410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N39L_56410	COG4191	Histidine kinase
N39L_56440	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
N39L_56470	COG0720	synthase
N39L_56510	COG1716	ATPase activity
N39L_56510	COG0842	Transport permease protein
N39L_56510	COG1131	(ABC) transporter
N39L_56560	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
N39L_56570	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
N39L_56600	COG0405	Gamma-glutamyltransferase
N39L_56660	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
N39L_56670	COG0291	Belongs to the bacterial ribosomal protein bL35 family
N39L_56680	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
N39L_56700	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
N39L_56730	COG1649	PFAM Uncharacterised BCR, COG1649
N39L_56790	COG1136	(ABC) transporter
N39L_56790	COG0577	efflux transmembrane transporter activity
N39L_56840	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
N39L_56850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N39L_56860	COG1136	(ABC) transporter
N39L_56860	COG0577	efflux transmembrane transporter activity
N39L_56870	COG2385	sporulation resulting in formation of a cellular spore
N39L_56880	COG2183	response to ionizing radiation
N39L_56910	COG2267	carboxylic ester hydrolase activity
N39L_56930	COG3540	Alkaline phosphatase
N39L_56960	COG0596	Alpha beta hydrolase
N39L_56970	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N39L_57000	COG0572	uridine kinase
N39L_57010	COG2815	serine threonine protein kinase
N39L_57010	COG0515	serine threonine protein kinase
N39L_57030	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
N39L_57040	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
N39L_57060	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
N39L_57070	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
N39L_57080	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
N39L_57120	COG0702	epimerase
N39L_57130	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
N39L_57170	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
N39L_57180	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
N39L_57230	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
N39L_57240	COG0052	Belongs to the universal ribosomal protein uS2 family
N39L_57300	COG1002	Type II restriction enzyme, methylase subunits
N39L_57310	COG1002	Type II restriction enzyme, methylase subunits
N39L_57540	COG1002	Type II restriction enzyme, methylase subunits
N39L_57780	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
N39L_57840	COG1061	Type III restriction enzyme res subunit
N39L_57850	COG1061	Type III restriction enzyme res subunit
N39L_57880	COG0285	dihydrofolate synthase activity
N39L_57910	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
N39L_57920	COG0133	tryptophan synthase activity
N39L_57990	COG0251	oxidation-reduction process
N39L_58030	COG1842	Phage shock protein A
N39L_58070	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
N39L_58080	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
N39L_58090	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
N39L_58100	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
N39L_58100	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
N39L_58120	COG0314	molybdopterin synthase activity
N39L_58130	COG1595	DNA-templated transcription, initiation
N39L_58180	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
N39L_58190	COG1983	PspC domain protein
N39L_58200	COG2081	HI0933 family
N39L_58360	COG0632	four-way junction helicase activity
N39L_58420	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
N39L_58420	COG0758	DNA mediated transformation
N39L_58440	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
N39L_58450	COG0859	PFAM glycosyl transferase family 9
N39L_58470	COG1968	undecaprenyl-diphosphatase activity
N39L_58490	COG0860	N-Acetylmuramoyl-L-alanine amidase
N39L_58500	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
N39L_58520	COG0596	Alpha beta hydrolase
N39L_58530	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
N39L_58540	COG0515	serine threonine protein kinase
N39L_58540	COG1357	PFAM Pentapeptide repeats (8 copies)
N39L_58580	COG0589	response to stress
N39L_58580	COG0475	glutathione-regulated potassium exporter activity
N39L_58590	COG0751	glycine-tRNA ligase activity
N39L_58610	COG0515	serine threonine protein kinase
N39L_58610	COG1357	PFAM Pentapeptide repeats (8 copies)
N39L_58650	COG1316	TRANSCRIPTIONal
N39L_58670	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
N39L_58740	COG1175	transmembrane transport
N39L_58770	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
N39L_58790	COG0649	NAD binding
N39L_58800	COG0275	rRNA processing
N39L_58830	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
N39L_58860	COG2205	protein histidine kinase activity
N39L_59070	COG1716	ATPase activity
N39L_59070	COG1131	(ABC) transporter
N39L_59070	COG0842	Transport permease protein
N39L_59080	COG3266	domain, Protein
N39L_59080	COG0515	serine threonine protein kinase
N39L_59110	COG0515	serine threonine protein kinase
N39L_59140	COG1475	DNA binding
N39L_59170	COG0515	serine threonine protein kinase
N39L_59250	COG1858	cytochrome C peroxidase
N39L_59300	COG0469	pyruvate kinase activity
N39L_59400	COG3243	poly(R)-hydroxyalkanoic acid synthase
N39L_59440	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
N39L_59470	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
N39L_59490	COG0559	Belongs to the binding-protein-dependent transport system permease family
N39L_59510	COG0411	ABC transporter
N39L_59530	COG2022	thiamine diphosphate biosynthetic process
N39L_59530	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N39L_59540	COG0300	oxidoreductase activity
N39L_59720	COG3788	relative of glutathione S-transferase, MAPEG superfamily
N39L_59740	COG5001	Diguanylate cyclase
N39L_59740	COG4251	negative regulation of phosphorylation
N39L_59740	COG3706	GGDEF domain
N39L_59740	COG2203	Gaf domain
N39L_59750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N39L_59800	COG0083	homoserine kinase activity
N39L_59850	COG1357	PFAM Pentapeptide repeats (8 copies)
N39L_59850	COG0515	serine threonine protein kinase
N39L_59910	COG0166	Belongs to the GPI family
N39L_59920	COG0857	belongs to the CobB CobQ family
N39L_59920	COG0280	phosphate acetyltransferase
N39L_59930	COG2203	Gaf domain
N39L_59930	COG2200	EAL domain
N39L_59930	COG2199	diguanylate cyclase activity
N39L_59940	COG1716	ATPase activity
N39L_59940	COG5001	Diguanylate cyclase
N39L_59960	COG1733	regulation of RNA biosynthetic process
N39L_59970	COG0574	Belongs to the PEP-utilizing enzyme family
N39L_59970	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
N39L_60010	COG4178	(ABC) transporter
N39L_60020	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
N39L_60040	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
N39L_60070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N39L_60070	COG4191	Histidine kinase
N39L_60080	COG1028	Short-chain dehydrogenase reductase Sdr
N39L_60210	COG0237	dephospho-CoA kinase activity
N39L_60220	COG5398	heme oxygenase
N39L_60230	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
N39L_60250	COG3852	Histidine kinase
N39L_60280	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
N39L_60310	COG0508	dehydrogenase complex catalyzes the overall conversion of
N39L_60310	COG0022	dehydrogenase e1 component
N39L_60320	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
N39L_60330	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
N39L_60360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N39L_60370	COG0409	Hydrogenase expression formation protein
N39L_60440	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
N39L_60450	COG2189	Belongs to the N(4) N(6)-methyltransferase family
N39L_60480	COG1573	uracil-dna glycosylase
N39L_60520	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
N39L_60540	COG0484	heat shock protein binding
N39L_60560	COG0456	acetyltransferase
N39L_60580	COG0746	molybdenum cofactor guanylyltransferase activity
N39L_60620	COG0443	Heat shock 70 kDa protein
N39L_60670	COG1505	serine-type exopeptidase activity
N39L_60690	COG0514	ATP-dependent DNA helicase (RecQ)
N39L_60710	COG0584	glycerophosphoryl diester phosphodiesterase
N39L_60740	COG3842	ATPase activity
N39L_60770	COG0756	dUTP diphosphatase activity
N39L_60780	COG2131	deaminase
N39L_60790	COG2304	oxidoreductase activity
N39L_61130	COG3852	Histidine kinase
N39L_61140	COG0515	serine threonine protein kinase
N39L_61140	COG2815	serine threonine protein kinase
N39L_61240	COG0312	modulator of DNA gyrase
N39L_61250	COG0312	modulator of DNA gyrase
N39L_61260	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
N39L_61290	COG0432	Pfam Uncharacterised protein family UPF0047
N39L_61320	COG2205	protein histidine kinase activity
N39L_61320	COG5002	protein histidine kinase activity
N39L_61320	COG0784	Response regulator, receiver
N39L_61330	COG0247	lactate metabolic process
N39L_61340	COG0277	FAD linked oxidase domain protein
N39L_61450	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
N39L_61490	COG5001	Diguanylate cyclase
N39L_61520	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
N39L_61540	COG1943	Transposase
N39L_61550	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
N39L_61560	COG2048	Heterodisulfide reductase, subunit B
N39L_61570	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N39L_61580	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
N39L_61590	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
N39L_61600	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
N39L_61640	COG0628	permease
N39L_61660	COG0745	RESPONSE REGULATOR receiver
N39L_61690	COG0827	DNA restriction-modification system
N39L_61700	COG0827	DNA restriction-modification system
N39L_61720	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
N39L_61730	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N39L_61750	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N39L_61770	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
N39L_61790	COG0482	sulfurtransferase activity
N39L_61800	COG1192	Involved in chromosome partitioning
N39L_61850	COG0230	Belongs to the bacterial ribosomal protein bL34 family
N39L_61860	COG0594	ribonuclease P activity
N39L_61880	COG0706	membrane insertase activity
N39L_61910	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
N39L_61940	COG3185	4-Hydroxyphenylpyruvate dioxygenase
N39L_61960	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
N39L_62040	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
N39L_62090	COG0667	Aldo Keto reductase
N39L_62120	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
N39L_62140	COG0343	queuine tRNA-ribosyltransferase activity
N39L_62170	COG1672	PFAM Archaeal ATPase
N39L_62180	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
N39L_62190	COG0571	ribonuclease III activity
N39L_62300	COG0535	radical SAM domain protein
N39L_62330	COG4636	protein conserved in cyanobacteria
N39L_62350	COG0404	The glycine cleavage system catalyzes the degradation of glycine
N39L_62570	COG1649	PFAM Uncharacterised BCR, COG1649
N39L_62580	COG1696	Membrane protein involved in D-alanine export
N39L_62590	COG0481	GTPase activity
N39L_62610	COG0681	Belongs to the peptidase S26 family
N39L_62660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N39L_62670	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
N39L_62680	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
N39L_62720	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N39L_62720	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N39L_62750	COG0745	RESPONSE REGULATOR receiver
N39L_62760	COG1366	Belongs to the anti-sigma-factor antagonist family
N39L_62780	COG0783	Belongs to the Dps family
N39L_62800	COG0539	negative regulation of cytoplasmic translation
N39L_62820	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
N39L_62830	COG2022	thiamine diphosphate biosynthetic process
N39L_62860	COG0745	RESPONSE REGULATOR receiver
N39L_62890	COG1193	negative regulation of DNA recombination
N39L_62950	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
N39L_62950	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
N39L_63100	COG1222	aaa ATPase
N39L_63120	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
N39L_63180	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N39L_63200	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
N39L_63220	COG0731	radical SAM domain protein
N39L_63280	COG0003	Pfam Anion-transporting ATPase
N39L_63370	COG1077	Cell shape determining protein MreB Mrl
N39L_63450	COG1132	(ABC) transporter
N39L_63470	COG0019	diaminopimelate decarboxylase activity
N39L_63510	COG2084	Dehydrogenase
N39L_63530	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
N39L_63540	COG0066	3-isopropylmalate dehydratase activity
N39L_63550	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
N39L_63560	COG0367	asparagine synthase
N39L_63610	COG0546	phosphoglycolate phosphatase activity
N39L_63630	COG4279	zinc finger
N39L_t00050	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity