locus-tag	class	description
ADLECEL_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ADLECEL_00020	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ADLECEL_00030	COG0594	ribonuclease P activity
ADLECEL_00040	COG0706	membrane insertase activity
ADLECEL_00050	COG1847	R3H domain protein
ADLECEL_00060	COG0357	Ribosomal RNA small subunit methyltransferase G
ADLECEL_00070	COG1192	Involved in chromosome partitioning
ADLECEL_00080	COG1475	DNA binding
ADLECEL_00090	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ADLECEL_00100	COG1181	Belongs to the D-alanine--D-alanine ligase family
ADLECEL_00120	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ADLECEL_00120	COG1199	ATP-dependent helicase activity
ADLECEL_00160	COG0629	single-stranded DNA binding
ADLECEL_00170	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ADLECEL_00180	COG0359	binds to the 23S rRNA
ADLECEL_00190	COG0305	Participates in initiation and elongation during chromosome replication
ADLECEL_00230	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ADLECEL_00270	COG3328	transposase activity
ADLECEL_00280	COG3328	transposase activity
ADLECEL_00300	COG1053	succinate dehydrogenase
ADLECEL_00300	COG3976	FMN-binding domain protein
ADLECEL_00310	COG0622	Phosphoesterase
ADLECEL_00320	COG3706	GGDEF domain
ADLECEL_00340	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ADLECEL_00350	COG0531	amino acid
ADLECEL_00380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ADLECEL_00410	COG1696	Membrane protein involved in D-alanine export
ADLECEL_00450	COG1396	sequence-specific DNA binding
ADLECEL_00460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ADLECEL_00470	COG0778	Nitroreductase
ADLECEL_00490	COG1192	Involved in chromosome partitioning
ADLECEL_00500	COG1475	DNA binding
ADLECEL_00540	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ADLECEL_00800	COG0791	NLP P60 protein
ADLECEL_00950	COG1012	belongs to the aldehyde dehydrogenase family
ADLECEL_00970	COG0546	phosphoglycolate phosphatase activity
ADLECEL_00990	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ADLECEL_01070	COG0864	Transcriptional regulator
ADLECEL_01130	COG0443	Heat shock 70 kDa protein
ADLECEL_01140	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ADLECEL_01150	COG0484	heat shock protein binding
ADLECEL_01160	COG0789	Transcriptional regulator
ADLECEL_01170	COG0542	response to heat
ADLECEL_01190	COG0393	Putative heavy-metal-binding
ADLECEL_01210	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ADLECEL_01220	COG3279	Response regulator of the LytR AlgR family
ADLECEL_01230	COG0166	Belongs to the GPI family
ADLECEL_01240	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ADLECEL_01250	COG0298	carbon dioxide binding
ADLECEL_01370	COG2197	response regulator
ADLECEL_01410	COG1610	YqeY-like protein
ADLECEL_01420	COG0437	4 iron, 4 sulfur cluster binding
ADLECEL_01430	COG0243	molybdopterin cofactor binding
ADLECEL_01450	COG0577	efflux transmembrane transporter activity
ADLECEL_01460	COG1136	(ABC) transporter
ADLECEL_01480	COG2205	protein histidine kinase activity
ADLECEL_01540	COG3428	Bacterial PH domain
ADLECEL_01550	COG4535	Mg2 and Co2 transporter CorC
ADLECEL_01570	COG0569	domain protein
ADLECEL_01610	COG1115	amino acid carrier protein
ADLECEL_01620	COG1763	Mo-molybdopterin cofactor biosynthetic process
ADLECEL_01640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADLECEL_01650	COG0765	amino acid transport
ADLECEL_01660	COG1126	abc transporter atp-binding protein
ADLECEL_01670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ADLECEL_01700	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ADLECEL_01720	COG3655	Transcriptional regulator
ADLECEL_01810	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ADLECEL_01840	COG0528	UMP kinase activity
ADLECEL_01850	COG0233	cytoplasmic translational termination
ADLECEL_01870	COG4589	Belongs to the CDS family
ADLECEL_01880	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ADLECEL_01900	COG0750	zinc metalloprotease
ADLECEL_01910	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ADLECEL_01920	COG0442	prolyl-tRNA aminoacylation
ADLECEL_01950	COG1053	succinate dehydrogenase
ADLECEL_01970	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ADLECEL_01990	COG3620	sequence-specific DNA binding
ADLECEL_02040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ADLECEL_02050	COG0542	response to heat
ADLECEL_02090	COG1053	succinate dehydrogenase
ADLECEL_02090	COG3976	FMN-binding domain protein
ADLECEL_02120	COG0745	RESPONSE REGULATOR receiver
ADLECEL_02130	COG5002	protein histidine kinase activity
ADLECEL_02150	COG0437	4 iron, 4 sulfur cluster binding
ADLECEL_02170	COG1136	(ABC) transporter
ADLECEL_02270	COG1410	methionine synthase
ADLECEL_02270	COG0646	methionine synthase
ADLECEL_02290	COG5012	cobalamin binding
ADLECEL_02320	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ADLECEL_02350	COG3328	transposase activity
ADLECEL_02360	COG0402	S-adenosylhomocysteine deaminase activity
ADLECEL_02380	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ADLECEL_02390	COG0085	RNA polymerase activity
ADLECEL_02400	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ADLECEL_02410	COG0583	DNA-binding transcription factor activity
ADLECEL_02530	COG0140	phosphoribosyl-ATP diphosphatase activity
ADLECEL_02540	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ADLECEL_02560	COG0733	neurotransmitter:sodium symporter activity
ADLECEL_02600	COG2076	Multidrug Resistance protein
ADLECEL_02640	COG2326	polyphosphate kinase activity
ADLECEL_02650	COG4509	Sortase family
ADLECEL_02660	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ADLECEL_02670	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ADLECEL_02680	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ADLECEL_02710	COG0138	bifunctional purine biosynthesis protein purh
ADLECEL_02760	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ADLECEL_02770	COG1053	succinate dehydrogenase
ADLECEL_02780	COG2197	response regulator
ADLECEL_02790	COG2304	oxidoreductase activity
ADLECEL_02810	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ADLECEL_02820	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ADLECEL_02830	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ADLECEL_02840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ADLECEL_02860	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ADLECEL_02910	COG2357	RelA SpoT domain protein
ADLECEL_02930	COG0215	cysteine-tRNA ligase activity
ADLECEL_02940	COG1053	succinate dehydrogenase
ADLECEL_02940	COG3976	FMN-binding domain protein
ADLECEL_02970	COG1131	(ABC) transporter
ADLECEL_03000	COG0826	peptidase U32
ADLECEL_03030	COG0545	Peptidyl-prolyl cis-trans isomerase
ADLECEL_03040	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ADLECEL_03050	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ADLECEL_03060	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ADLECEL_03070	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ADLECEL_03080	COG0137	argininosuccinate synthase activity
ADLECEL_03100	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ADLECEL_03120	COG0826	peptidase U32
ADLECEL_03130	COG1053	succinate dehydrogenase
ADLECEL_03150	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ADLECEL_03210	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ADLECEL_03230	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ADLECEL_03240	COG3383	formate dehydrogenase (NAD+) activity
ADLECEL_03250	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ADLECEL_03260	COG0651	ATP synthesis coupled electron transport
ADLECEL_03270	COG0650	Formate hydrogenlyase subunit 4
ADLECEL_03280	COG4237	Hydrogenase 4 membrane
ADLECEL_03290	COG0651	ATP synthesis coupled electron transport
ADLECEL_03300	COG3261	NADH dehydrogenase
ADLECEL_03300	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
ADLECEL_03310	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADLECEL_03320	COG3260	NADH ubiquinone oxidoreductase 20
ADLECEL_03340	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ADLECEL_03350	COG2116	formate transmembrane transporter activity
ADLECEL_03360	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ADLECEL_03400	COG0586	Pfam SNARE associated Golgi protein
ADLECEL_03410	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ADLECEL_03420	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ADLECEL_03430	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ADLECEL_03460	COG1288	antiporter activity
ADLECEL_03480	COG0024	Methionine aminopeptidase
ADLECEL_03500	COG0697	spore germination
ADLECEL_03520	COG0477	Major facilitator Superfamily
ADLECEL_03550	COG0484	heat shock protein binding
ADLECEL_03610	COG1924	4 iron, 4 sulfur cluster binding
ADLECEL_03620	COG2814	Major facilitator Superfamily
ADLECEL_03680	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ADLECEL_03750	COG3550	peptidyl-serine autophosphorylation
ADLECEL_03770	COG0326	Molecular chaperone. Has ATPase activity
ADLECEL_03810	COG3956	TIGRFAM MazG family protein
ADLECEL_03830	COG3976	FMN-binding domain protein
ADLECEL_03830	COG1053	succinate dehydrogenase
ADLECEL_03840	COG1228	amidohydrolase
ADLECEL_03850	COG2235	arginine
ADLECEL_03860	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ADLECEL_03870	COG0549	Belongs to the carbamate kinase family
ADLECEL_03890	COG1834	amidinotransferase
ADLECEL_03920	COG0477	Major facilitator Superfamily
ADLECEL_03940	COG1834	amidinotransferase
ADLECEL_03960	COG1053	succinate dehydrogenase
ADLECEL_03960	COG3976	FMN-binding domain protein
ADLECEL_03970	COG0583	DNA-binding transcription factor activity
ADLECEL_03990	COG0436	Aminotransferase
ADLECEL_04040	COG2414	aldehyde ferredoxin oxidoreductase
ADLECEL_04050	COG0437	4 iron, 4 sulfur cluster binding
ADLECEL_04090	COG1876	peptidase activity
ADLECEL_04160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ADLECEL_04200	COG0482	sulfurtransferase activity
ADLECEL_04210	COG1053	succinate dehydrogenase
ADLECEL_04220	COG2197	response regulator
ADLECEL_04240	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ADLECEL_04250	COG2205	protein histidine kinase activity
ADLECEL_04250	COG0784	Response regulator, receiver
ADLECEL_04320	COG0437	4 iron, 4 sulfur cluster binding
ADLECEL_04330	COG0542	response to heat
ADLECEL_04370	COG2197	response regulator
ADLECEL_04590	COG0560	Phosphoserine phosphatase
ADLECEL_04650	COG2843	Capsule synthesis protein
ADLECEL_04660	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ADLECEL_04680	COG0604	alcohol dehydrogenase
ADLECEL_04680	COG1028	Short-chain dehydrogenase reductase Sdr
ADLECEL_04680	COG3321	synthase
ADLECEL_04710	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ADLECEL_04720	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ADLECEL_04720	COG0825	malonyl-CoA metabolic process
ADLECEL_04730	COG1748	Saccharopine dehydrogenase
ADLECEL_04770	COG1131	(ABC) transporter
ADLECEL_04820	COG2815	serine threonine protein kinase
ADLECEL_04820	COG0515	serine threonine protein kinase
ADLECEL_04860	COG1968	undecaprenyl-diphosphatase activity
ADLECEL_04880	COG1725	Transcriptional regulator
ADLECEL_04910	COG3550	peptidyl-serine autophosphorylation
ADLECEL_04950	COG0243	molybdopterin cofactor binding
ADLECEL_04960	COG0437	4 iron, 4 sulfur cluster binding
ADLECEL_05020	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ADLECEL_05070	COG3845	ABC transporter
ADLECEL_05080	COG1122	ATPase activity
ADLECEL_05090	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ADLECEL_05110	COG0657	acetylesterase activity
ADLECEL_05120	COG3973	AAA domain
ADLECEL_05170	COG0789	Transcriptional regulator
ADLECEL_05200	COG1201	RNA secondary structure unwinding
ADLECEL_05220	COG1201	RNA secondary structure unwinding
ADLECEL_05270	COG0824	Thioesterase
ADLECEL_05280	COG3254	rhamnose metabolic process
ADLECEL_05300	COG2848	UPF0210 protein
ADLECEL_05320	COG3550	peptidyl-serine autophosphorylation
ADLECEL_05330	COG0288	reversible hydration of carbon dioxide
ADLECEL_05360	COG1725	Transcriptional regulator
ADLECEL_05370	COG0243	molybdopterin cofactor binding
ADLECEL_05380	COG0437	4 iron, 4 sulfur cluster binding
ADLECEL_05420	COG1316	TRANSCRIPTIONal
ADLECEL_05520	COG0822	iron-sulfur transferase activity
ADLECEL_05540	COG1959	2 iron, 2 sulfur cluster binding
ADLECEL_05550	COG0784	Response regulator, receiver
ADLECEL_05550	COG2205	protein histidine kinase activity
ADLECEL_05560	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ADLECEL_05560	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ADLECEL_05570	COG0084	hydrolase, TatD family'
ADLECEL_05590	COG3550	peptidyl-serine autophosphorylation
ADLECEL_05620	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ADLECEL_05640	COG1247	-acetyltransferase
ADLECEL_05650	COG0514	ATP-dependent DNA helicase (RecQ)
ADLECEL_05670	COG0538	isocitrate dehydrogenase activity
ADLECEL_05690	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ADLECEL_05700	COG2197	response regulator
ADLECEL_05750	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ADLECEL_05760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ADLECEL_05770	COG0437	4 iron, 4 sulfur cluster binding
ADLECEL_05780	COG0243	molybdopterin cofactor binding
ADLECEL_05810	COG0348	domain, Protein
ADLECEL_05840	COG1138	Cytochrome C-type biogenesis protein
ADLECEL_05850	COG4555	ABC transporter
ADLECEL_05910	COG1733	regulation of RNA biosynthetic process
ADLECEL_05950	COG1053	succinate dehydrogenase
ADLECEL_05950	COG3976	FMN-binding domain protein
ADLECEL_05990	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ADLECEL_06030	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ADLECEL_06040	COG2003	Belongs to the UPF0758 family
ADLECEL_06060	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ADLECEL_06070	COG3177	Filamentation induced by cAMP protein fic
ADLECEL_06120	COG3328	transposase activity
ADLECEL_06170	COG3853	Toxic anion resistance protein (TelA)
ADLECEL_06180	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ADLECEL_06210	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ADLECEL_06230	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ADLECEL_06240	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ADLECEL_06250	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ADLECEL_06260	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ADLECEL_06270	COG0006	proline dipeptidase activity
ADLECEL_06290	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ADLECEL_06330	COG1053	succinate dehydrogenase
ADLECEL_06340	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
ADLECEL_06360	COG0511	ligase activity, forming carbon-carbon bonds
ADLECEL_06360	COG5016	pyruvate
ADLECEL_06370	COG0439	Biotin carboxylase
ADLECEL_06390	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ADLECEL_06410	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ADLECEL_06430	COG0004	ammonium transporteR
ADLECEL_06440	COG0347	Belongs to the P(II) protein family
ADLECEL_06490	COG0539	negative regulation of cytoplasmic translation
ADLECEL_06500	COG0237	dephospho-CoA kinase activity
ADLECEL_06510	COG2197	response regulator
ADLECEL_06520	COG1053	succinate dehydrogenase
ADLECEL_06560	COG0556	nucleotide-excision repair
ADLECEL_06580	COG0497	DNA recombination
ADLECEL_06620	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ADLECEL_06630	COG0072	phenylalanine-tRNA ligase activity
ADLECEL_06640	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ADLECEL_06650	COG0736	holo-[acyl-carrier-protein] synthase activity
ADLECEL_06670	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ADLECEL_06670	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ADLECEL_06710	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ADLECEL_06730	COG1705	Flagellar rod assembly protein muramidase FlgJ
ADLECEL_06730	COG3942	CHAP domain
ADLECEL_06740	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ADLECEL_06780	COG0653	protein targeting
ADLECEL_06790	COG3657	addiction module killer protein
ADLECEL_06810	COG1682	transport, permease protein
ADLECEL_06820	COG1134	teichoic acid transport
ADLECEL_06830	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ADLECEL_06880	COG3328	transposase activity
ADLECEL_06890	COG3328	transposase activity
ADLECEL_06960	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ADLECEL_06990	COG1216	Glycosyl transferase, family 2
ADLECEL_07110	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ADLECEL_07120	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ADLECEL_07140	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ADLECEL_07190	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ADLECEL_07210	COG1215	transferase activity, transferring glycosyl groups
ADLECEL_07210	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ADLECEL_07240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ADLECEL_07250	COG1696	Membrane protein involved in D-alanine export
ADLECEL_07310	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ADLECEL_07340	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ADLECEL_07350	COG0463	Glycosyl transferase, family 2
ADLECEL_07380	COG0151	Belongs to the GarS family
ADLECEL_07390	COG1088	dTDP-glucose 4,6-dehydratase activity
ADLECEL_07400	COG4193	domain, Protein
ADLECEL_07410	COG1376	ErfK ybiS ycfS ynhG family protein
ADLECEL_07430	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ADLECEL_07470	COG1773	rubredoxin
ADLECEL_07470	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ADLECEL_07490	COG0343	queuine tRNA-ribosyltransferase activity
ADLECEL_07500	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ADLECEL_07550	COG2197	response regulator
ADLECEL_07560	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ADLECEL_07560	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ADLECEL_07580	COG2197	response regulator
ADLECEL_07610	COG0535	radical SAM domain protein
ADLECEL_07630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADLECEL_07640	COG1120	ATPase activity
ADLECEL_07660	COG1122	ATPase activity
ADLECEL_07670	COG1122	ATPase activity
ADLECEL_07680	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ADLECEL_07700	COG1115	amino acid carrier protein
ADLECEL_07710	COG1115	amino acid carrier protein
ADLECEL_07720	COG2081	HI0933 family
ADLECEL_07730	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
ADLECEL_07740	COG2267	carboxylic ester hydrolase activity
ADLECEL_07750	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ADLECEL_07770	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ADLECEL_07800	COG2131	deaminase
ADLECEL_07820	COG0356	it plays a direct role in the translocation of protons across the membrane
ADLECEL_07840	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ADLECEL_07850	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ADLECEL_07860	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ADLECEL_07870	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ADLECEL_07880	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ADLECEL_07950	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ADLECEL_07990	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ADLECEL_08020	COG0101	tRNA pseudouridine synthase activity
ADLECEL_08030	COG4656	Part of a membrane complex involved in electron transport
ADLECEL_08050	COG0733	neurotransmitter:sodium symporter activity
ADLECEL_08060	COG0012	GTP binding
ADLECEL_08100	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ADLECEL_08110	COG0154	amidase activity
ADLECEL_08120	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ADLECEL_08140	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
ADLECEL_08160	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ADLECEL_08180	COG0674	pyruvate-flavodoxin oxidoreductase activity
ADLECEL_08190	COG1013	pyruvate-flavodoxin oxidoreductase activity
ADLECEL_08210	COG1053	succinate dehydrogenase
ADLECEL_08250	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ADLECEL_08310	COG2235	arginine
ADLECEL_08320	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ADLECEL_08330	COG1288	antiporter activity
ADLECEL_08340	COG0018	arginyl-trna synthetase
ADLECEL_08370	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ADLECEL_08370	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ADLECEL_08410	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ADLECEL_08430	COG0025	NhaP-type Na H and K H
ADLECEL_08440	COG0180	Tryptophanyl-tRNA synthetase
ADLECEL_08460	COG0494	nUDIX hydrolase
ADLECEL_08470	COG0488	(ABC) transporter
ADLECEL_08490	COG0025	NhaP-type Na H and K H
ADLECEL_08520	COG1053	succinate dehydrogenase
ADLECEL_08520	COG3976	FMN-binding domain protein
ADLECEL_08530	COG3976	FMN-binding domain protein
ADLECEL_08530	COG1053	succinate dehydrogenase
ADLECEL_08540	COG1994	Peptidase M50
ADLECEL_08560	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ADLECEL_08570	COG1187	pseudouridine synthase activity
ADLECEL_08580	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ADLECEL_08590	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ADLECEL_08620	COG2205	protein histidine kinase activity
ADLECEL_08620	COG0784	Response regulator, receiver
ADLECEL_08690	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ADLECEL_08700	COG0204	Acyl-transferase
ADLECEL_08710	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ADLECEL_08730	COG1160	GTP binding
ADLECEL_08740	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ADLECEL_08750	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ADLECEL_08760	COG2205	protein histidine kinase activity
ADLECEL_08760	COG5002	protein histidine kinase activity
ADLECEL_08760	COG0784	Response regulator, receiver
ADLECEL_08780	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ADLECEL_08790	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ADLECEL_08800	COG1104	cysteine desulfurase activity
ADLECEL_08840	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ADLECEL_08850	COG1302	Protein conserved in bacteria
ADLECEL_08860	COG1461	Dihydroxyacetone kinase
ADLECEL_08870	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ADLECEL_08880	COG0742	ribosomal rna small subunit methyltransferase
ADLECEL_08910	COG0038	chloride channel
ADLECEL_08920	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ADLECEL_08930	COG0416	fatty acid biosynthetic process
ADLECEL_08940	COG0571	ribonuclease III activity
ADLECEL_08950	COG1196	nuclear chromosome segregation
ADLECEL_08970	COG0243	molybdopterin cofactor binding
ADLECEL_09000	COG0243	molybdopterin cofactor binding
ADLECEL_09050	COG0243	molybdopterin cofactor binding
ADLECEL_09080	COG2226	methyltransferase
ADLECEL_09100	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ADLECEL_09110	COG1215	transferase activity, transferring glycosyl groups
ADLECEL_09150	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ADLECEL_09190	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ADLECEL_09210	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ADLECEL_09230	COG0513	Belongs to the DEAD box helicase family
ADLECEL_09240	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ADLECEL_09270	COG1597	lipid kinase activity
ADLECEL_09280	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ADLECEL_09290	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ADLECEL_09310	COG0105	UTP biosynthetic process
ADLECEL_09360	COG1077	Cell shape determining protein MreB Mrl
ADLECEL_09370	COG1792	Involved in formation and maintenance of cell shape
ADLECEL_09400	COG0772	Belongs to the SEDS family
ADLECEL_09440	COG0537	adenosine 5'-monophosphoramidase activity
ADLECEL_09470	COG1151	hydroxylamine reductase activity
ADLECEL_09480	COG2816	NAD+ diphosphatase activity
ADLECEL_09510	COG0335	large ribosomal subunit rRNA binding
ADLECEL_09520	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ADLECEL_09530	COG0792	nuclease activity
ADLECEL_09540	COG0606	chelatase, subunit chli
ADLECEL_09550	COG0758	DNA mediated transformation
ADLECEL_09560	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
ADLECEL_09600	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ADLECEL_09620	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ADLECEL_09640	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ADLECEL_09760	COG1074	ATP-dependent DNA helicase activity
ADLECEL_09800	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ADLECEL_09820	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ADLECEL_09840	COG0318	PFAM AMP-dependent synthetase and ligase
ADLECEL_09880	COG1960	acyl-CoA dehydrogenase activity
ADLECEL_09900	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ADLECEL_09910	COG2086	electron transfer activity
ADLECEL_09920	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ADLECEL_09930	COG0247	lactate metabolic process
ADLECEL_09930	COG2181	nitrate reductase activity
ADLECEL_09970	COG0318	PFAM AMP-dependent synthetase and ligase
ADLECEL_09980	COG0318	PFAM AMP-dependent synthetase and ligase
ADLECEL_10030	COG0243	molybdopterin cofactor binding
ADLECEL_10040	COG0437	4 iron, 4 sulfur cluster binding
ADLECEL_10090	COG0243	molybdopterin cofactor binding
ADLECEL_10100	COG1140	nitrate reductase beta subunit
ADLECEL_10110	COG0437	4 iron, 4 sulfur cluster binding
ADLECEL_10140	COG1846	Transcriptional regulator
ADLECEL_10150	COG0243	molybdopterin cofactor binding
ADLECEL_10160	COG0437	4 iron, 4 sulfur cluster binding
ADLECEL_10210	COG0437	4 iron, 4 sulfur cluster binding
ADLECEL_10260	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ADLECEL_10300	COG4134	Bacterial extracellular solute-binding protein
ADLECEL_10310	COG1177	transmembrane transport
ADLECEL_10330	COG3842	ATPase activity
ADLECEL_10380	COG1960	acyl-CoA dehydrogenase activity
ADLECEL_10400	COG0583	DNA-binding transcription factor activity
ADLECEL_10410	COG0779	Required for maturation of 30S ribosomal subunits
ADLECEL_10420	COG0195	Participates in both transcription termination and antitermination
ADLECEL_10440	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ADLECEL_10440	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ADLECEL_10450	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ADLECEL_10460	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ADLECEL_10470	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ADLECEL_10480	COG0196	riboflavin kinase activity
ADLECEL_10490	COG1368	sulfuric ester hydrolase activity
ADLECEL_10500	COG0322	excinuclease ABC activity
ADLECEL_10510	COG0322	excinuclease ABC activity
ADLECEL_10520	COG1660	Displays ATPase and GTPase activities
ADLECEL_10530	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ADLECEL_10540	COG1481	regulation of sporulation
ADLECEL_10560	COG0126	phosphoglycerate kinase activity
ADLECEL_10570	COG0149	triose-phosphate isomerase activity
ADLECEL_10580	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ADLECEL_10590	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ADLECEL_10620	COG0861	Integral membrane protein TerC family
ADLECEL_10650	COG1597	lipid kinase activity
ADLECEL_10660	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ADLECEL_10670	COG2738	Putative neutral zinc metallopeptidase
ADLECEL_10680	COG1570	exodeoxyribonuclease VII activity
ADLECEL_10690	COG1722	exodeoxyribonuclease VII activity
ADLECEL_10700	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ADLECEL_10710	COG1053	succinate dehydrogenase
ADLECEL_10710	COG3976	FMN-binding domain protein
ADLECEL_10730	COG0280	phosphate acetyltransferase
ADLECEL_10750	COG1215	transferase activity, transferring glycosyl groups
ADLECEL_10760	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ADLECEL_10770	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ADLECEL_10780	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ADLECEL_10800	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ADLECEL_10810	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ADLECEL_10820	COG0564	pseudouridine synthase activity
ADLECEL_10830	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ADLECEL_10840	COG3976	FMN-binding domain protein
ADLECEL_10840	COG1053	succinate dehydrogenase
ADLECEL_10880	COG1053	succinate dehydrogenase
ADLECEL_10880	COG3976	FMN-binding domain protein
ADLECEL_10890	COG2197	response regulator
ADLECEL_10900	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ADLECEL_10910	COG1053	succinate dehydrogenase
ADLECEL_10910	COG3976	FMN-binding domain protein
ADLECEL_10950	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ADLECEL_10950	COG2111	Na H antiporter
ADLECEL_10960	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ADLECEL_10970	COG3260	NADH ubiquinone oxidoreductase 20
ADLECEL_11000	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ADLECEL_11020	COG2720	vancomycin resistance protein
ADLECEL_11050	COG1686	Belongs to the peptidase S11 family
ADLECEL_11100	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
ADLECEL_11110	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ADLECEL_11150	COG0756	dUTP diphosphatase activity
ADLECEL_11160	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ADLECEL_11180	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ADLECEL_11190	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ADLECEL_11210	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ADLECEL_11220	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ADLECEL_11230	COG2359	stage V sporulation protein S
ADLECEL_11250	COG1418	mRNA catabolic process
ADLECEL_11280	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ADLECEL_11290	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ADLECEL_11300	COG1666	GTP binding
ADLECEL_11330	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ADLECEL_11340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ADLECEL_11350	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ADLECEL_11360	COG1185	polyribonucleotide nucleotidyltransferase activity
ADLECEL_11370	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ADLECEL_11410	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ADLECEL_11440	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ADLECEL_11460	COG0484	heat shock protein binding
ADLECEL_11470	COG1420	regulation of RNA biosynthetic process
ADLECEL_11480	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ADLECEL_11490	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ADLECEL_11520	COG0481	GTPase activity
ADLECEL_11530	COG0268	Binds directly to 16S ribosomal RNA
ADLECEL_11560	COG0658	competence protein
ADLECEL_11560	COG2333	competence protein COMEC
ADLECEL_11570	COG1555	photosystem II stabilization
ADLECEL_11570	COG1596	polysaccharide export
ADLECEL_11580	COG0301	tRNA thio-modification
ADLECEL_11600	COG0194	GDP metabolic process
ADLECEL_11620	COG0284	orotidine-5'-phosphate decarboxylase activity
ADLECEL_11630	COG0167	dihydroorotate dehydrogenase activity
ADLECEL_11640	COG0543	2 iron, 2 sulfur cluster binding
ADLECEL_11650	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ADLECEL_11660	COG0505	Belongs to the CarA family
ADLECEL_11720	COG1120	ATPase activity
ADLECEL_11730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADLECEL_11740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADLECEL_11750	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ADLECEL_11760	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ADLECEL_11770	COG0540	Belongs to the ATCase OTCase family
ADLECEL_11780	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ADLECEL_11790	COG1592	Rubrerythrin
ADLECEL_11800	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
ADLECEL_11820	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ADLECEL_11860	COG0674	pyruvate-flavodoxin oxidoreductase activity
ADLECEL_11860	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ADLECEL_11870	COG1144	Oxidoreductase
ADLECEL_11890	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ADLECEL_11910	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ADLECEL_11910	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ADLECEL_11920	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ADLECEL_11930	COG0242	peptide deformylase activity
ADLECEL_11940	COG0358	DNA primase activity
ADLECEL_11950	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ADLECEL_11960	COG0328	RNA-DNA hybrid ribonuclease activity
ADLECEL_11980	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ADLECEL_11990	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ADLECEL_12000	COG0440	acetolactate synthase activity
ADLECEL_12010	COG0028	Belongs to the TPP enzyme family
ADLECEL_12020	COG0129	dihydroxy-acid dehydratase activity
ADLECEL_12050	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ADLECEL_12060	COG2890	protein-(glutamine-N5) methyltransferase activity
ADLECEL_12070	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ADLECEL_12110	COG0437	4 iron, 4 sulfur cluster binding
ADLECEL_12120	COG0243	molybdopterin cofactor binding
ADLECEL_12140	COG0569	domain protein
ADLECEL_12140	COG0475	glutathione-regulated potassium exporter activity
ADLECEL_12160	COG0492	ferredoxin-NADP+ reductase activity
ADLECEL_12170	COG4145	pantothenate transmembrane transporter activity
ADLECEL_12190	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ADLECEL_12220	COG0525	valine-tRNA ligase activity
ADLECEL_12230	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ADLECEL_12240	COG0740	serine-type endopeptidase activity
ADLECEL_12250	COG0544	peptidyl-prolyl cis-trans isomerase activity
ADLECEL_12450	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
ADLECEL_12460	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ADLECEL_12460	COG0116	Belongs to the methyltransferase superfamily
ADLECEL_12470	COG0116	Belongs to the methyltransferase superfamily
ADLECEL_12470	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ADLECEL_12480	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ADLECEL_12490	COG0745	RESPONSE REGULATOR receiver
ADLECEL_12510	COG0437	4 iron, 4 sulfur cluster binding
ADLECEL_12520	COG0243	molybdopterin cofactor binding
ADLECEL_12550	COG1053	succinate dehydrogenase
ADLECEL_12560	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ADLECEL_12570	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ADLECEL_12600	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ADLECEL_12630	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ADLECEL_12690	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ADLECEL_12750	COG3328	transposase activity
ADLECEL_12760	COG3328	transposase activity
ADLECEL_12770	COG1476	TRANSCRIPTIONal
ADLECEL_12870	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ADLECEL_12880	COG0077	Prephenate dehydratase
ADLECEL_12880	COG1605	Chorismate mutase
ADLECEL_12910	COG1194	a g-specific adenine glycosylase
ADLECEL_12940	COG1132	(ABC) transporter
ADLECEL_12970	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ADLECEL_13030	COG1192	Involved in chromosome partitioning
ADLECEL_13040	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ADLECEL_13060	COG0574	Belongs to the PEP-utilizing enzyme family
ADLECEL_13060	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ADLECEL_13080	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ADLECEL_13090	COG0751	glycine-tRNA ligase activity
ADLECEL_13100	COG0752	glycyl-tRNA synthetase alpha subunit
ADLECEL_13110	COG0681	Belongs to the peptidase S26 family
ADLECEL_13120	COG0336	Belongs to the RNA methyltransferase TrmD family
ADLECEL_13130	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ADLECEL_13140	COG1837	Belongs to the UPF0109 family
ADLECEL_13180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ADLECEL_13190	COG0601	transmembrane transport
ADLECEL_13220	COG0552	protein localization to endoplasmic reticulum
ADLECEL_13230	COG0733	neurotransmitter:sodium symporter activity
ADLECEL_13250	COG0557	exoribonuclease II activity
ADLECEL_13270	COG2177	Part of the ABC transporter FtsEX involved in
ADLECEL_13280	COG2884	Cell division ATP-binding protein ftsE
ADLECEL_13290	COG3958	Transketolase
ADLECEL_13310	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ADLECEL_13320	COG0653	protein targeting
ADLECEL_13340	COG1294	oxidase, subunit
ADLECEL_13350	COG1271	oxidase subunit
ADLECEL_13400	COG0799	negative regulation of ribosome biogenesis
ADLECEL_13410	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ADLECEL_13410	COG1713	HD superfamily hydrolase involved in NAD metabolism
ADLECEL_13420	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ADLECEL_13430	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ADLECEL_13440	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ADLECEL_13450	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ADLECEL_13460	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ADLECEL_13470	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ADLECEL_13480	COG1288	antiporter activity
ADLECEL_13490	COG2235	arginine
ADLECEL_13500	COG2197	response regulator
ADLECEL_13510	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ADLECEL_13510	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ADLECEL_13520	COG0745	RESPONSE REGULATOR receiver
ADLECEL_13530	COG0174	glutamine synthetase
ADLECEL_13550	COG2033	superoxide reductase activity
ADLECEL_13560	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ADLECEL_13590	COG0316	Belongs to the HesB IscA family
ADLECEL_13590	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ADLECEL_13610	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ADLECEL_13650	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ADLECEL_13650	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ADLECEL_13690	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ADLECEL_13700	COG0583	DNA-binding transcription factor activity
ADLECEL_13720	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ADLECEL_13740	COG0107	imidazoleglycerol-phosphate synthase activity
ADLECEL_13750	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ADLECEL_13760	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ADLECEL_13770	COG0131	Imidazoleglycerol-phosphate dehydratase
ADLECEL_13780	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ADLECEL_13790	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ADLECEL_13800	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ADLECEL_13810	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
ADLECEL_13820	COG1691	(AIR) carboxylase
ADLECEL_13830	COG0789	Transcriptional regulator
ADLECEL_13850	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ADLECEL_13890	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ADLECEL_13900	COG1363	Peptidase, m42
ADLECEL_13950	COG3409	Peptidoglycan-binding domain 1 protein
ADLECEL_14610	COG1307	EDD domain protein, DegV family
ADLECEL_14640	COG1307	EDD domain protein, DegV family
ADLECEL_14650	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ADLECEL_14660	COG1774	PSP1 C-terminal conserved region
ADLECEL_14680	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ADLECEL_14690	COG0281	malic enzyme
ADLECEL_14710	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ADLECEL_14710	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ADLECEL_14720	COG0551	DNA topoisomerase type I activity
ADLECEL_14720	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ADLECEL_14780	COG0765	amino acid transport
ADLECEL_14790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADLECEL_14810	COG3872	metal-dependent enzyme
ADLECEL_14820	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
ADLECEL_14830	COG2226	methyltransferase
ADLECEL_14840	COG1278	Cold shock
ADLECEL_14860	COG2255	four-way junction helicase activity
ADLECEL_14870	COG0632	four-way junction helicase activity
ADLECEL_14880	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ADLECEL_14910	COG1028	Short-chain dehydrogenase reductase Sdr
ADLECEL_14920	COG0217	transcriptional regulatory protein
ADLECEL_14930	COG2909	trisaccharide binding
ADLECEL_14940	COG1053	succinate dehydrogenase
ADLECEL_14960	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ADLECEL_14980	COG3976	FMN-binding domain protein
ADLECEL_14980	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
ADLECEL_15000	COG0437	4 iron, 4 sulfur cluster binding
ADLECEL_15010	COG0243	molybdopterin cofactor binding
ADLECEL_15030	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ADLECEL_15040	COG4149	molybdate abc transporter
ADLECEL_15070	COG0617	tRNA 3'-terminal CCA addition
ADLECEL_15110	COG1053	succinate dehydrogenase
ADLECEL_15120	COG0351	phosphomethylpyrimidine kinase
ADLECEL_15130	COG1335	isochorismatase
ADLECEL_15140	COG0352	thiamine-phosphate diphosphorylase activity
ADLECEL_15150	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ADLECEL_15180	COG0762	integral membrane protein
ADLECEL_15190	COG1799	cell septum assembly
ADLECEL_15220	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ADLECEL_15230	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ADLECEL_15240	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ADLECEL_15250	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ADLECEL_15260	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ADLECEL_15270	COG0772	Belongs to the SEDS family
ADLECEL_15280	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ADLECEL_15320	COG0768	penicillin binding
ADLECEL_15340	COG0275	rRNA processing
ADLECEL_15350	COG2001	Belongs to the MraZ family
ADLECEL_15360	COG4974	Belongs to the 'phage' integrase family
ADLECEL_15370	COG0252	asparaginase activity
ADLECEL_15380	COG2860	membrane
ADLECEL_15390	COG4868	Belongs to the UPF0371 family
ADLECEL_15410	COG0504	CTP synthase activity
ADLECEL_15430	COG1396	sequence-specific DNA binding
ADLECEL_15430	COG1917	Cupin 2, conserved barrel domain protein
ADLECEL_15450	COG0024	Methionine aminopeptidase
ADLECEL_15460	COG0728	peptidoglycan biosynthetic process
ADLECEL_15470	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ADLECEL_15480	COG0081	regulation of translation
ADLECEL_15490	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ADLECEL_15500	COG0250	Participates in transcription elongation, termination and antitermination
ADLECEL_15510	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ADLECEL_15520	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ADLECEL_15550	COG0426	domain, Protein
ADLECEL_15560	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ADLECEL_15570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ADLECEL_15590	COG1794	racemase activity, acting on amino acids and derivatives
ADLECEL_15620	COG1725	Transcriptional regulator
ADLECEL_15650	COG0437	4 iron, 4 sulfur cluster binding
ADLECEL_15660	COG0243	molybdopterin cofactor binding
ADLECEL_15670	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
ADLECEL_15670	COG3976	FMN-binding domain protein
ADLECEL_15710	COG0747	negative chemotaxis
ADLECEL_15730	COG0563	adenylate kinase activity
ADLECEL_15750	COG0200	Binds to the 23S rRNA
ADLECEL_15760	COG1841	ribosomal large subunit assembly
ADLECEL_15770	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ADLECEL_15780	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ADLECEL_15790	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ADLECEL_15800	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ADLECEL_15810	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ADLECEL_15820	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ADLECEL_15830	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ADLECEL_15840	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ADLECEL_15850	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ADLECEL_15870	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ADLECEL_15880	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ADLECEL_15900	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ADLECEL_15910	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ADLECEL_15970	COG0544	peptidyl-prolyl cis-trans isomerase activity
ADLECEL_16000	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ADLECEL_16010	COG1053	succinate dehydrogenase
ADLECEL_16040	COG1136	(ABC) transporter
ADLECEL_16100	COG2197	response regulator
ADLECEL_16130	COG0089	rRNA binding
ADLECEL_16140	COG0088	Forms part of the polypeptide exit tunnel
ADLECEL_16150	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ADLECEL_16160	COG0051	transcription antitermination factor activity, RNA binding
ADLECEL_16170	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ADLECEL_16180	COG0049	tRNA binding
ADLECEL_16190	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ADLECEL_16200	COG2195	Cleaves the N-terminal amino acid of tripeptides
ADLECEL_16210	COG1227	inorganic diphosphatase activity
ADLECEL_16220	COG1760	l-serine dehydratase
ADLECEL_16240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ADLECEL_16290	COG0494	nUDIX hydrolase
ADLECEL_16310	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ADLECEL_16340	COG2860	membrane
ADLECEL_16360	COG0306	phosphate transporter
ADLECEL_16370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ADLECEL_16380	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ADLECEL_16390	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ADLECEL_16390	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ADLECEL_16400	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ADLECEL_16410	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ADLECEL_16420	COG0602	queuosine metabolic process
ADLECEL_16430	COG0720	synthase
ADLECEL_16440	COG3328	transposase activity
ADLECEL_16450	COG3328	transposase activity
ADLECEL_16460	COG0583	DNA-binding transcription factor activity
ADLECEL_16480	COG2197	response regulator
ADLECEL_16490	COG1739	Uncharacterized protein family UPF0029
ADLECEL_16500	COG0488	(ABC) transporter
ADLECEL_16510	COG2814	Major facilitator Superfamily
ADLECEL_16520	COG0193	aminoacyl-tRNA hydrolase activity
ADLECEL_16530	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ADLECEL_16540	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ADLECEL_16560	COG2217	Heavy metal translocating P-type atpase
ADLECEL_16570	COG1937	Protein conserved in bacteria
ADLECEL_16600	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ADLECEL_16620	COG0598	Magnesium transport protein CorA
ADLECEL_16630	COG1573	uracil-dna glycosylase
ADLECEL_16640	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ADLECEL_16650	COG0521	Mo-molybdopterin cofactor biosynthetic process
ADLECEL_16660	COG0303	'Molybdopterin
ADLECEL_16670	COG1132	(ABC) transporter
ADLECEL_16680	COG2197	response regulator
ADLECEL_16690	COG1053	succinate dehydrogenase
ADLECEL_16690	COG3976	FMN-binding domain protein
ADLECEL_16700	COG2814	Major facilitator Superfamily
ADLECEL_16720	COG4716	Myosin-crossreactive antigen
ADLECEL_16740	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ADLECEL_16760	COG0203	ribosomal protein L17
ADLECEL_16770	COG0202	RNA polymerase activity
ADLECEL_16780	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ADLECEL_16790	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ADLECEL_16810	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ADLECEL_16820	COG0189	ligase activity
ADLECEL_16820	COG2918	glutathione biosynthetic process
ADLECEL_16830	COG2814	Major facilitator Superfamily
ADLECEL_16890	COG0459	protein refolding
ADLECEL_16900	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ADLECEL_16910	COG2197	response regulator
ADLECEL_16920	COG4585	Histidine kinase
ADLECEL_16930	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ADLECEL_16930	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ADLECEL_16950	COG0805	protein transport
ADLECEL_16960	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ADLECEL_16980	COG0402	S-adenosylhomocysteine deaminase activity
ADLECEL_16990	COG2226	methyltransferase
ADLECEL_17020	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
ADLECEL_17060	COG0437	4 iron, 4 sulfur cluster binding
ADLECEL_17070	COG0243	molybdopterin cofactor binding
ADLECEL_17080	COG0330	HflC and HflK could
ADLECEL_17110	COG0745	RESPONSE REGULATOR receiver
ADLECEL_17120	COG2205	protein histidine kinase activity
ADLECEL_17150	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ADLECEL_17190	COG0802	atpase or kinase
ADLECEL_17200	COG2116	formate transmembrane transporter activity
ADLECEL_17210	COG3976	FMN-binding domain protein
ADLECEL_17210	COG1053	succinate dehydrogenase
ADLECEL_17220	COG2909	trisaccharide binding
ADLECEL_17230	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ADLECEL_17240	COG3404	Formiminotransferase-cyclodeaminase
ADLECEL_17250	COG2759	Belongs to the formate--tetrahydrofolate ligase family
ADLECEL_17260	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ADLECEL_17270	COG0745	RESPONSE REGULATOR receiver
ADLECEL_17300	COG1268	BioY protein
ADLECEL_17330	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ADLECEL_17340	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ADLECEL_17350	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ADLECEL_17360	COG0424	maF-like protein
ADLECEL_17380	COG0037	tRNA processing
ADLECEL_17390	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ADLECEL_17400	COG1950	PFAM Membrane protein of
ADLECEL_17410	COG0577	efflux transmembrane transporter activity
ADLECEL_17410	COG1136	(ABC) transporter
ADLECEL_17420	COG1528	Iron-storage protein
ADLECEL_17430	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ADLECEL_17440	COG1272	protein, Hemolysin III
ADLECEL_17450	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ADLECEL_17520	COG0656	L-ascorbic acid biosynthetic process
ADLECEL_17530	COG2078	PFAM AMMECR1 domain protein
ADLECEL_17530	COG3885	ferrous iron binding
ADLECEL_17540	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
ADLECEL_17550	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ADLECEL_17560	COG3250	beta-galactosidase activity
ADLECEL_17600	COG1053	succinate dehydrogenase
ADLECEL_17680	COG0437	4 iron, 4 sulfur cluster binding
ADLECEL_17690	COG0243	molybdopterin cofactor binding
ADLECEL_17700	COG0583	DNA-binding transcription factor activity
ADLECEL_17710	COG0656	L-ascorbic acid biosynthetic process
ADLECEL_17730	COG1490	D-aminoacyl-tRNA deacylase activity
ADLECEL_17740	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ADLECEL_17790	COG1373	ATPase (AAA superfamily
ADLECEL_17810	COG0613	PHP domain protein
ADLECEL_17820	COG4778	phosphonate C-P lyase system protein PhnL
ADLECEL_17830	COG3454	Phosphonate metabolism
ADLECEL_17840	COG4107	phosphonate C-P lyase system protein PhnK
ADLECEL_17850	COG3627	carbon phosphorus lyase activity
ADLECEL_17890	COG3639	organic phosphonate transmembrane transporter activity
ADLECEL_17900	COG3639	organic phosphonate transmembrane transporter activity
ADLECEL_17910	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ADLECEL_17940	COG1115	amino acid carrier protein
ADLECEL_17950	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ADLECEL_17970	COG1132	(ABC) transporter
ADLECEL_17980	COG3973	AAA domain
ADLECEL_18010	COG1234	tRNA 3'-trailer cleavage
ADLECEL_18030	COG2205	protein histidine kinase activity
ADLECEL_18030	COG0784	Response regulator, receiver
ADLECEL_18110	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ADLECEL_18110	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ADLECEL_18140	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ADLECEL_18200	COG1053	succinate dehydrogenase
ADLECEL_18220	COG1028	Short-chain dehydrogenase reductase Sdr
ADLECEL_18240	COG3976	FMN-binding domain protein
ADLECEL_18240	COG1053	succinate dehydrogenase
ADLECEL_18250	COG0446	pyridine nucleotide-disulphide oxidoreductase
ADLECEL_18280	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ADLECEL_18300	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
ADLECEL_18320	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ADLECEL_18360	COG0549	Belongs to the carbamate kinase family
ADLECEL_18380	COG2153	protein acetylation
ADLECEL_18410	COG0659	secondary active sulfate transmembrane transporter activity
ADLECEL_18420	COG1053	succinate dehydrogenase
ADLECEL_18460	COG0569	domain protein
ADLECEL_18470	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ADLECEL_18500	COG2832	Protein of unknown function (DUF454)
ADLECEL_18510	COG0363	glucosamine-6-phosphate deaminase activity
ADLECEL_18520	COG0659	secondary active sulfate transmembrane transporter activity
ADLECEL_18530	COG1028	Short-chain dehydrogenase reductase Sdr
ADLECEL_18720	COG3657	addiction module killer protein
ADLECEL_18730	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ADLECEL_18780	COG0640	Transcriptional regulator
ADLECEL_18790	COG2217	Heavy metal translocating P-type atpase
ADLECEL_18800	COG2217	Heavy metal translocating P-type atpase
ADLECEL_18810	COG2217	Heavy metal translocating P-type atpase
ADLECEL_18840	COG0222	ribosome binding
ADLECEL_18850	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ADLECEL_18860	COG2197	response regulator
ADLECEL_18870	COG1053	succinate dehydrogenase
ADLECEL_18890	COG1487	ribonuclease activity
ADLECEL_18910	COG0124	histidyl-tRNA synthetase
ADLECEL_18920	COG0473	3-isopropylmalate dehydrogenase activity
ADLECEL_18930	COG0066	3-isopropylmalate dehydratase activity
ADLECEL_18940	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ADLECEL_18960	COG0142	geranyltranstransferase activity
ADLECEL_18990	COG3976	FMN-binding domain protein
ADLECEL_18990	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
ADLECEL_19010	COG0437	4 iron, 4 sulfur cluster binding
ADLECEL_19020	COG0243	molybdopterin cofactor binding
ADLECEL_19030	COG0745	RESPONSE REGULATOR receiver
ADLECEL_19040	COG2205	protein histidine kinase activity
ADLECEL_19100	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ADLECEL_19100	COG1918	ferrous iron import across plasma membrane
ADLECEL_19230	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
ADLECEL_19330	COG1002	Type II restriction enzyme, methylase subunits
ADLECEL_19370	COG0582	viral genome integration into host DNA
ADLECEL_19440	COG1131	(ABC) transporter
ADLECEL_19450	COG4585	Histidine kinase
ADLECEL_19460	COG2197	response regulator
ADLECEL_19480	COG1917	Cupin 2, conserved barrel domain protein
ADLECEL_19480	COG4977	sequence-specific DNA binding
ADLECEL_19490	COG0697	spore germination
ADLECEL_19540	COG0488	(ABC) transporter
ADLECEL_19560	COG1131	(ABC) transporter
ADLECEL_19600	COG2197	response regulator
ADLECEL_19620	COG1053	succinate dehydrogenase
ADLECEL_19620	COG3976	FMN-binding domain protein
ADLECEL_19670	COG1136	(ABC) transporter
ADLECEL_19680	COG5002	protein histidine kinase activity
ADLECEL_19690	COG0745	RESPONSE REGULATOR receiver
ADLECEL_19700	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ADLECEL_19720	COG1309	transcriptional regulator
ADLECEL_19760	COG2205	protein histidine kinase activity
ADLECEL_19760	COG0784	Response regulator, receiver
ADLECEL_19770	COG0495	leucyl-tRNA aminoacylation
ADLECEL_19790	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ADLECEL_19810	COG0583	DNA-binding transcription factor activity
ADLECEL_19850	COG1592	Rubrerythrin
ADLECEL_19860	COG1362	aminopeptidase activity
ADLECEL_19870	COG0549	Belongs to the carbamate kinase family
ADLECEL_19890	COG2235	arginine
ADLECEL_19920	COG2957	Belongs to the agmatine deiminase family
ADLECEL_19930	COG0531	amino acid
ADLECEL_19970	COG1574	metal-dependent hydrolase with the TIM-barrel fold
ADLECEL_19980	COG4584	PFAM Integrase catalytic
ADLECEL_20040	COG0549	Belongs to the carbamate kinase family
ADLECEL_20050	COG2957	Belongs to the agmatine deiminase family
ADLECEL_20060	COG0531	amino acid
ADLECEL_20070	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ADLECEL_20110	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ADLECEL_20120	COG0477	Major facilitator Superfamily
ADLECEL_20160	COG0745	RESPONSE REGULATOR receiver
ADLECEL_20170	COG5002	protein histidine kinase activity
ADLECEL_20170	COG3850	Histidine kinase
ADLECEL_20320	COG2205	protein histidine kinase activity
ADLECEL_20340	COG1131	(ABC) transporter
ADLECEL_20350	COG0745	RESPONSE REGULATOR receiver
ADLECEL_20400	COG2814	Major facilitator Superfamily
ADLECEL_20410	COG0235	Class ii aldolase
ADLECEL_20420	COG4806	L-rhamnose isomerase
ADLECEL_20420	COG1070	Carbohydrate kinase
ADLECEL_20430	COG1070	Carbohydrate kinase
ADLECEL_20480	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ADLECEL_20490	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ADLECEL_20530	COG0067	glutamate synthase
ADLECEL_20540	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ADLECEL_20540	COG0069	glutamate synthase activity
ADLECEL_20550	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ADLECEL_20550	COG0069	glutamate synthase activity
ADLECEL_20580	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
ADLECEL_20590	COG2873	o-acetylhomoserine
ADLECEL_20780	COG1396	sequence-specific DNA binding
ADLECEL_20810	COG0460	homoserine dehydrogenase
ADLECEL_20830	COG0019	diaminopimelate decarboxylase activity
ADLECEL_20860	COG0733	neurotransmitter:sodium symporter activity
ADLECEL_20890	COG0398	Pfam SNARE associated Golgi protein
ADLECEL_20920	COG1181	Belongs to the D-alanine--D-alanine ligase family
ADLECEL_20930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ADLECEL_20960	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ADLECEL_20980	COG0515	serine threonine protein kinase
ADLECEL_20980	COG2815	serine threonine protein kinase
ADLECEL_20990	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ADLECEL_21010	COG3275	phosphorelay sensor kinase activity
ADLECEL_21020	COG0730	response to heat
ADLECEL_21040	COG1162	GTPase activity
ADLECEL_21060	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ADLECEL_21090	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ADLECEL_21100	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ADLECEL_21120	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ADLECEL_21130	COG5002	protein histidine kinase activity
ADLECEL_21140	COG0745	RESPONSE REGULATOR receiver
ADLECEL_21160	COG1472	Belongs to the glycosyl hydrolase 3 family
ADLECEL_21170	COG0785	Cytochrome C biogenesis protein
ADLECEL_21180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ADLECEL_21220	COG2770	Histidine kinase
ADLECEL_21220	COG2208	phosphoserine phosphatase activity
ADLECEL_21230	COG1366	Belongs to the anti-sigma-factor antagonist family
ADLECEL_21240	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ADLECEL_21380	COG4974	Belongs to the 'phage' integrase family
ADLECEL_21440	COG2239	Acts as a magnesium transporter
ADLECEL_21460	COG1959	2 iron, 2 sulfur cluster binding
ADLECEL_21470	COG1757	Na H antiporter
ADLECEL_21510	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ADLECEL_21520	COG1169	isochorismate synthase
ADLECEL_21530	COG3830	Belongs to the UPF0237 family
ADLECEL_21540	COG0302	gtp cyclohydrolase
ADLECEL_21570	COG0708	Exodeoxyribonuclease III
ADLECEL_21580	COG1316	TRANSCRIPTIONal
ADLECEL_21600	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ADLECEL_21640	COG0437	4 iron, 4 sulfur cluster binding
ADLECEL_21650	COG0243	molybdopterin cofactor binding
ADLECEL_21660	COG0583	DNA-binding transcription factor activity
ADLECEL_21670	COG1053	succinate dehydrogenase
ADLECEL_21690	COG3177	Filamentation induced by cAMP protein fic
ADLECEL_21720	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ADLECEL_21730	COG3189	MarR family transcriptional regulator
ADLECEL_21740	COG2233	PERMEase
ADLECEL_21790	COG3706	GGDEF domain
ADLECEL_21830	COG0025	NhaP-type Na H and K H
ADLECEL_21840	COG0519	Catalyzes the synthesis of GMP from XMP
ADLECEL_21970	COG1396	sequence-specific DNA binding
ADLECEL_21990	COG0657	acetylesterase activity
ADLECEL_22000	COG0454	-acetyltransferase
ADLECEL_22020	COG2207	Transcriptional regulator
ADLECEL_22020	COG3708	Transcriptional regulator
ADLECEL_22030	COG0456	acetyltransferase
ADLECEL_22040	COG0477	Major facilitator Superfamily
ADLECEL_22080	COG2066	Belongs to the glutaminase family
ADLECEL_22090	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ADLECEL_22110	COG1307	EDD domain protein, DegV family
ADLECEL_22120	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ADLECEL_22180	COG1393	Belongs to the ArsC family
ADLECEL_22220	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ADLECEL_22270	COG0531	amino acid
ADLECEL_22310	COG2223	nitrite transmembrane transporter activity
ADLECEL_22350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ADLECEL_22360	COG1120	ATPase activity
ADLECEL_22410	COG3093	addiction module antidote protein HigA
ADLECEL_22450	COG0433	COG0433 Predicted ATPase
ADLECEL_22460	COG0390	transport system, permease component
ADLECEL_22650	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ADLECEL_22730	COG0784	Response regulator, receiver
ADLECEL_22730	COG2205	protein histidine kinase activity
ADLECEL_22750	COG3437	response regulator, receiver
ADLECEL_22770	COG0745	RESPONSE REGULATOR receiver
ADLECEL_22780	COG2205	protein histidine kinase activity
ADLECEL_22790	COG0437	4 iron, 4 sulfur cluster binding
ADLECEL_22800	COG0243	molybdopterin cofactor binding
ADLECEL_22890	COG3177	Filamentation induced by cAMP protein fic
ADLECEL_22930	COG0765	amino acid transport
ADLECEL_22940	COG1126	abc transporter atp-binding protein
ADLECEL_22950	COG2223	nitrite transmembrane transporter activity
ADLECEL_22970	COG0280	phosphate acetyltransferase
ADLECEL_23080	COG1842	Phage shock protein A
ADLECEL_23140	COG0631	protein serine/threonine phosphatase activity
ADLECEL_23160	COG2815	serine threonine protein kinase
ADLECEL_23160	COG0515	serine threonine protein kinase
ADLECEL_23190	COG5002	protein histidine kinase activity
ADLECEL_23200	COG0745	RESPONSE REGULATOR receiver
ADLECEL_23210	COG1283	sodium-dependent phosphate transmembrane transporter activity
ADLECEL_23220	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ADLECEL_23230	COG0581	inorganic phosphate transmembrane transporter activity
ADLECEL_23240	COG0573	inorganic phosphate transmembrane transporter activity
ADLECEL_23260	COG1785	Belongs to the alkaline phosphatase family
ADLECEL_23290	COG1328	CTP reductase activity
ADLECEL_23310	COG1122	ATPase activity
ADLECEL_23400	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ADLECEL_23430	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
ADLECEL_23440	COG0644	oxidoreductase
ADLECEL_23450	COG0446	pyridine nucleotide-disulphide oxidoreductase
ADLECEL_23450	COG1902	pentaerythritol trinitrate reductase activity
ADLECEL_23470	COG1028	Short-chain dehydrogenase reductase Sdr
ADLECEL_23480	COG0431	NADPH-dependent FMN reductase
ADLECEL_23480	COG3976	FMN-binding domain protein
ADLECEL_23480	COG1053	succinate dehydrogenase
ADLECEL_23570	COG1053	succinate dehydrogenase
ADLECEL_23600	COG1047	Peptidyl-prolyl cis-trans
ADLECEL_23680	COG1979	alcohol dehydrogenase
ADLECEL_23710	COG0726	polysaccharide deacetylase
ADLECEL_23720	COG1045	serine acetyltransferase
ADLECEL_23730	COG2814	Major facilitator Superfamily
ADLECEL_23740	COG1253	flavin adenine dinucleotide binding
ADLECEL_23760	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ADLECEL_23770	COG1217	gtp-binding protein TYPA
ADLECEL_23840	COG4804	nuclease activity
ADLECEL_23960	COG3328	transposase activity
ADLECEL_24310	COG0270	DNA (cytosine-5-)-methyltransferase activity
ADLECEL_24630	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ADLECEL_24640	COG0187	DNA topoisomerase II activity
ADLECEL_24650	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP