locus-tag	class	description
AACERI_AaceriAAL007C	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AACERI_AaceriAAL012C	COG0473	3-isopropylmalate dehydrogenase activity
AACERI_AaceriAAL013W	COG1104	cysteine desulfurase activity
AACERI_AaceriAAL020C	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AACERI_AaceriAAL021W	COG0440	acetolactate synthase activity
AACERI_AaceriAAL022W	COG0538	isocitrate dehydrogenase activity
AACERI_AaceriAAL024C	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AACERI_AaceriAAL028W	COG0488	(ABC) transporter
AACERI_AaceriAAL029W	COG0515	serine threonine protein kinase
AACERI_AaceriAAL029W	COG2815	serine threonine protein kinase
AACERI_AaceriAAL035W	COG2226	methyltransferase
AACERI_AaceriAAL043C	COG0443	Heat shock 70 kDa protein
AACERI_AaceriAAL044C	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AACERI_AaceriAAL061C	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AACERI_AaceriAAL065C	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AACERI_AaceriAAL071C	COG1012	belongs to the aldehyde dehydrogenase family
AACERI_AaceriAAL072C	COG0557	exoribonuclease II activity
AACERI_AaceriAAL073W	COG3961	Belongs to the TPP enzyme family
AACERI_AaceriAAL074C	COG0233	cytoplasmic translational termination
AACERI_AaceriAAL080W	COG1205	dead DEAH box helicase
AACERI_AaceriAAL080W	COG1111	helicase
AACERI_AaceriAAL088W	COG0495	leucyl-tRNA aminoacylation
AACERI_AaceriAAL093C	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AACERI_AaceriAAL099C	COG0417	DNA replication proofreading
AACERI_AaceriAAL103W	COG0484	heat shock protein binding
AACERI_AaceriAAL113W	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AACERI_AaceriAAL115W	COG0109	protoheme IX farnesyltransferase activity
AACERI_AaceriAAL121C	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AACERI_AaceriAAL121C	COG2124	cytochrome p450
AACERI_AaceriAAL131C	COG0688	phosphatidylethanolamine metabolic process
AACERI_AaceriAAL133W	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AACERI_AaceriAAL134W	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AACERI_AaceriAAL136C	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AACERI_AaceriAAL137W	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
AACERI_AaceriAAL141C	COG0644	oxidoreductase
AACERI_AaceriAAL164C	COG0513	Belongs to the DEAD box helicase family
AACERI_AaceriAAL177W	COG1185	polyribonucleotide nucleotidyltransferase activity
AACERI_AaceriAAL182W	COG1196	nuclear chromosome segregation
AACERI_AaceriAAL182W	COG1196	nuclear chromosome segregation
AACERI_AaceriAAR009W	COG1357	PFAM Pentapeptide repeats (8 copies)
AACERI_AaceriAAR009W	COG0515	serine threonine protein kinase
AACERI_AaceriAAR020W	COG1643	Atp-dependent helicase
AACERI_AaceriAAR025C	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AACERI_AaceriAAR034W	COG0525	valine-tRNA ligase activity
AACERI_AaceriAAR037W	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AACERI_AaceriAAR045C	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AACERI_AaceriAAR047C	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AACERI_AaceriAAR059C	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AACERI_AaceriAAR067W	COG0335	large ribosomal subunit rRNA binding
AACERI_AaceriAAR071W	COG4770	biotin carboxylase activity
AACERI_AaceriAAR072C	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AACERI_AaceriAAR082W	COG0004	ammonium transporteR
AACERI_AaceriAAR098W	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AACERI_AaceriAAR120C	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AACERI_AaceriAAR125C	COG3118	belongs to the thioredoxin family
AACERI_AaceriAAR128W	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AACERI_AaceriAAR130C	COG1394	ATPase activity, coupled to movement of substances
AACERI_AaceriAAR132C	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AACERI_AaceriAAR136W	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AACERI_AaceriAAR140W	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AACERI_AaceriAAR143W	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AACERI_AaceriAAR144W	COG0405	Gamma-glutamyltransferase
AACERI_AaceriAAR147W	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AACERI_AaceriAAR152W	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AACERI_AaceriAAR152W	COG1648	precorrin-2 dehydrogenase activity
AACERI_AaceriAAR162C	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AACERI_AaceriAAR167C	COG0022	dehydrogenase e1 component
AACERI_AaceriAAR168C	COG0318	PFAM AMP-dependent synthetase and ligase
AACERI_AaceriAAR170W	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AACERI_AaceriAAR177W	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AACERI_AaceriAAR180C	COG1643	Atp-dependent helicase
AACERI_AaceriAAR186W	COG0259	pyridoxamine-phosphate oxidase activity
AACERI_AaceriABL004W	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AACERI_AaceriABL028W	COG0515	serine threonine protein kinase
AACERI_AaceriABL029W	COG0033	Phosphoglucomutase
AACERI_AaceriABL034W	COG2815	serine threonine protein kinase
AACERI_AaceriABL034W	COG0515	serine threonine protein kinase
AACERI_AaceriABL035C	COG1362	aminopeptidase activity
AACERI_AaceriABL036C	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AACERI_AaceriABL040W	COG2814	Major facilitator Superfamily
AACERI_AaceriABL041W	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AACERI_AaceriABL048W	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AACERI_AaceriABL054C	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AACERI_AaceriABL077W	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AACERI_AaceriABL088C	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AACERI_AaceriABL102C	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AACERI_AaceriABL104C	COG0156	8-amino-7-oxononanoate synthase activity
AACERI_AaceriABL106C	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AACERI_AaceriABL107C	COG0181	hydroxymethylbilane synthase activity
AACERI_AaceriABL111C	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AACERI_AaceriABL125W	COG2040	homocysteine
AACERI_AaceriABL126W	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AACERI_AaceriABL132W	COG2226	methyltransferase
AACERI_AaceriABL134C	COG0724	RNA recognition motif
AACERI_AaceriABL138W	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AACERI_AaceriABL144C	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AACERI_AaceriABL161C	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AACERI_AaceriABL161C	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AACERI_AaceriABL174C	COG0443	Heat shock 70 kDa protein
AACERI_AaceriABL183W	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AACERI_AaceriABL184W	COG0647	UMP catabolic process
AACERI_AaceriABL186W	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AACERI_AaceriABL194C	COG0484	heat shock protein binding
AACERI_AaceriABL195C	COG0625	glutathione transferase activity
AACERI_AaceriABL203W	COG1404	Belongs to the peptidase S8 family
AACERI_AaceriABL204W	COG3579	cysteine-type endopeptidase activity
AACERI_AaceriABL205C	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AACERI_AaceriABL205C	COG4624	Iron only hydrogenase large subunit, C-terminal domain
AACERI_AaceriABL206C	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AACERI_AaceriABL209C	COG0656	L-ascorbic acid biosynthetic process
AACERI_AaceriABR010C	COG0052	Belongs to the universal ribosomal protein uS2 family
AACERI_AaceriABR019C	COG2255	four-way junction helicase activity
AACERI_AaceriABR040W	COG0012	GTP binding
AACERI_AaceriABR046C	COG2154	pterin-4-alpha-carbinolamine dehydratase
AACERI_AaceriABR063C	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AACERI_AaceriABR065W	COG0571	ribonuclease III activity
AACERI_AaceriABR068C	COG0191	fructose-bisphosphate aldolase activity
AACERI_AaceriABR094W	COG0667	Aldo Keto reductase
AACERI_AaceriABR096C	COG0105	UTP biosynthetic process
AACERI_AaceriABR122C	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
AACERI_AaceriABR123W	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AACERI_AaceriABR124C	COG1953	Uracil, thiamine, allantoin
AACERI_AaceriABR125C	COG1716	ATPase activity
AACERI_AaceriABR125C	COG1131	(ABC) transporter
AACERI_AaceriABR125C	COG0842	Transport permease protein
AACERI_AaceriABR126W	COG1132	(ABC) transporter
AACERI_AaceriABR133W	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AACERI_AaceriABR137W	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AACERI_AaceriABR139W	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AACERI_AaceriABR140C	COG0154	amidase activity
AACERI_AaceriABR142W	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AACERI_AaceriABR145C	COG0156	8-amino-7-oxononanoate synthase activity
AACERI_AaceriABR148W	COG0049	tRNA binding
AACERI_AaceriABR157W	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AACERI_AaceriABR161C	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AACERI_AaceriABR168W	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AACERI_AaceriABR169W	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AACERI_AaceriABR170W	COG0354	folic acid binding
AACERI_AaceriABR171W	COG0049	tRNA binding
AACERI_AaceriABR179C	COG0724	RNA recognition motif
AACERI_AaceriABR184C	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AACERI_AaceriABR186W	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AACERI_AaceriABR192W	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AACERI_AaceriABR209W	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AACERI_AaceriABR212C	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AACERI_AaceriABR223C	COG2814	Major facilitator Superfamily
AACERI_AaceriABR227C	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AACERI_AaceriABR228C	COG2132	Multicopper oxidase
AACERI_AaceriABR229C	COG1063	alcohol dehydrogenase
AACERI_AaceriABR246W	COG1028	Short-chain dehydrogenase reductase Sdr
AACERI_AaceriACL021C	COG0277	FAD linked oxidase domain protein
AACERI_AaceriACL028W	COG0006	proline dipeptidase activity
AACERI_AaceriACL032C	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AACERI_AaceriACL035C	COG0167	dihydroorotate dehydrogenase activity
AACERI_AaceriACL039W	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AACERI_AaceriACL044W	COG1012	belongs to the aldehyde dehydrogenase family
AACERI_AaceriACL053C	COG0515	serine threonine protein kinase
AACERI_AaceriACL053C	COG2815	serine threonine protein kinase
AACERI_AaceriACL059C	COG0626	cystathionine gamma-synthase activity
AACERI_AaceriACL068W	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AACERI_AaceriACL069C	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AACERI_AaceriACL077C	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AACERI_AaceriACL098C	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AACERI_AaceriACL107C	COG0656	L-ascorbic acid biosynthetic process
AACERI_AaceriACL109C	COG0492	ferredoxin-NADP+ reductase activity
AACERI_AaceriACL120W	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AACERI_AaceriACL121C	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AACERI_AaceriACL126W	COG0235	Class ii aldolase
AACERI_AaceriACL129W	COG2086	electron transfer activity
AACERI_AaceriACL130C	COG3830	Belongs to the UPF0237 family
AACERI_AaceriACL130C	COG0560	Phosphoserine phosphatase
AACERI_AaceriACL131W	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AACERI_AaceriACL135W	COG0833	amino acid
AACERI_AaceriACL136W	COG0012	GTP binding
AACERI_AaceriACL155W	COG1793	dna ligase
AACERI_AaceriACL162C	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
AACERI_AaceriACL172C	COG2814	Major facilitator Superfamily
AACERI_AaceriACL174W	COG0318	PFAM AMP-dependent synthetase and ligase
AACERI_AaceriACL176W	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AACERI_AaceriACL190W	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AACERI_AaceriACL196W	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AACERI_AaceriACL197W	COG0450	alkyl hydroperoxide reductase
AACERI_AaceriACL198W	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AACERI_AaceriACR013C	COG0114	fumarate hydratase activity
AACERI_AaceriACR022W	COG1132	(ABC) transporter
AACERI_AaceriACR026W	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AACERI_AaceriACR037C	COG1914	H( )-stimulated, divalent metal cation uptake system
AACERI_AaceriACR038W	COG0443	Heat shock 70 kDa protein
AACERI_AaceriACR045W	COG0459	protein refolding
AACERI_AaceriACR050C	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AACERI_AaceriACR052W	COG1053	succinate dehydrogenase
AACERI_AaceriACR055W	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AACERI_AaceriACR056W	COG0588	phosphoglycerate mutase activity
AACERI_AaceriACR069C	COG0612	Peptidase, M16
AACERI_AaceriACR070W	COG0083	homoserine kinase activity
AACERI_AaceriACR084C	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AACERI_AaceriACR089C	COG0180	Tryptophanyl-tRNA synthetase
AACERI_AaceriACR106C	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AACERI_AaceriACR108C	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AACERI_AaceriACR112C	COG0822	iron-sulfur transferase activity
AACERI_AaceriACR117W	COG0515	serine threonine protein kinase
AACERI_AaceriACR117W	COG2815	serine threonine protein kinase
AACERI_AaceriACR118W	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AACERI_AaceriACR119W	COG0515	serine threonine protein kinase
AACERI_AaceriACR119W	COG2815	serine threonine protein kinase
AACERI_AaceriACR128C	COG1121	(ABC) transporter
AACERI_AaceriACR134W	COG0285	dihydrofolate synthase activity
AACERI_AaceriACR136C	COG0585	pseudouridine synthase activity
AACERI_AaceriACR155W	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AACERI_AaceriACR155W	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AACERI_AaceriACR170C	COG0563	adenylate kinase activity
AACERI_AaceriACR187W	COG0124	histidyl-tRNA synthetase
AACERI_AaceriACR191C	COG0515	serine threonine protein kinase
AACERI_AaceriACR191C	COG2815	serine threonine protein kinase
AACERI_AaceriACR200C	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AACERI_AaceriACR202W	COG0493	'glutamate synthase
AACERI_AaceriACR210C	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AACERI_AaceriACR211W	COG3961	Belongs to the TPP enzyme family
AACERI_AaceriACR215C	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AACERI_AaceriACR217C	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AACERI_AaceriACR226W	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AACERI_AaceriACR233W	COG0442	prolyl-tRNA aminoacylation
AACERI_AaceriACR249C	COG0515	serine threonine protein kinase
AACERI_AaceriACR249C	COG2815	serine threonine protein kinase
AACERI_AaceriACR256C	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AACERI_AaceriACR268C	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AACERI_AaceriACR281C	COG2815	serine threonine protein kinase
AACERI_AaceriACR281C	COG0515	serine threonine protein kinase
AACERI_AaceriACR286C	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AACERI_AaceriACR293C	COG2175	clavaminate synthase activity
AACERI_AaceriADL006W	COG0489	protein tyrosine kinase activity
AACERI_AaceriADL018W	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AACERI_AaceriADL024C	COG0513	Belongs to the DEAD box helicase family
AACERI_AaceriADL031W	COG2873	o-acetylhomoserine
AACERI_AaceriADL032W	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AACERI_AaceriADL039C	COG0017	Asparaginyl-tRNA synthetase
AACERI_AaceriADL053C	COG0515	serine threonine protein kinase
AACERI_AaceriADL057W	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AACERI_AaceriADL057W	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AACERI_AaceriADL062W	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AACERI_AaceriADL066C	COG2224	Isocitrate lyase
AACERI_AaceriADL071C	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AACERI_AaceriADL072C	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AACERI_AaceriADL077C	COG0251	oxidation-reduction process
AACERI_AaceriADL079C	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AACERI_AaceriADL081C	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AACERI_AaceriADL098C	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AACERI_AaceriADL099C	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AACERI_AaceriADL099C	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AACERI_AaceriADL102C	COG0515	serine threonine protein kinase
AACERI_AaceriADL102C	COG2815	serine threonine protein kinase
AACERI_AaceriADL109W	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AACERI_AaceriADL111W	COG0484	heat shock protein binding
AACERI_AaceriADL116C	COG2205	protein histidine kinase activity
AACERI_AaceriADL117W	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AACERI_AaceriADL129W	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AACERI_AaceriADL154C	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AACERI_AaceriADL154C	COG0678	peroxiredoxin activity
AACERI_AaceriADL159C	COG1914	H( )-stimulated, divalent metal cation uptake system
AACERI_AaceriADL164C	COG0039	L-malate dehydrogenase activity
AACERI_AaceriADL191W	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AACERI_AaceriADL214C	COG0473	3-isopropylmalate dehydrogenase activity
AACERI_AaceriADL215W	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AACERI_AaceriADL215W	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AACERI_AaceriADL217W	COG2815	serine threonine protein kinase
AACERI_AaceriADL217W	COG0515	serine threonine protein kinase
AACERI_AaceriADL223W	COG0473	3-isopropylmalate dehydrogenase activity
AACERI_AaceriADL226C	COG0288	reversible hydration of carbon dioxide
AACERI_AaceriADL249W	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AACERI_AaceriADL256W	COG2890	protein-(glutamine-N5) methyltransferase activity
AACERI_AaceriADL258W	COG2814	Major facilitator Superfamily
AACERI_AaceriADL265W	COG0123	including yeast histone deacetylase and acetoin utilization protein
AACERI_AaceriADL268C	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AACERI_AaceriADL269W	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AACERI_AaceriADL270C	COG0131	Imidazoleglycerol-phosphate dehydratase
AACERI_AaceriADL272W	COG0833	amino acid
AACERI_AaceriADL273C	COG0513	Belongs to the DEAD box helicase family
AACERI_AaceriADL278C	COG1160	GTP binding
AACERI_AaceriADL284C	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AACERI_AaceriADL287C	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AACERI_AaceriADL290W	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AACERI_AaceriADL292C	COG1028	Short-chain dehydrogenase reductase Sdr
AACERI_AaceriADL296C	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AACERI_AaceriADL296C	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AACERI_AaceriADL301C	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AACERI_AaceriADL304W	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AACERI_AaceriADL305C	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AACERI_AaceriADL308C	COG0456	acetyltransferase
AACERI_AaceriADL327W	COG0484	heat shock protein binding
AACERI_AaceriADL345C	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AACERI_AaceriADL365W	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AACERI_AaceriADL366W	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AACERI_AaceriADL370C	COG2895	sulfate adenylyltransferase (ATP) activity
AACERI_AaceriADL373W	COG0423	glycine-tRNA ligase activity
AACERI_AaceriADL384W	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AACERI_AaceriADL385C	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AACERI_AaceriADL388W	COG4999	Histidine kinase
AACERI_AaceriADL388W	COG3850	Histidine kinase
AACERI_AaceriADL388W	COG3437	response regulator, receiver
AACERI_AaceriADL388W	COG2205	protein histidine kinase activity
AACERI_AaceriADR003C	COG1482	cell wall glycoprotein biosynthetic process
AACERI_AaceriADR011C	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AACERI_AaceriADR015W	COG0484	heat shock protein binding
AACERI_AaceriADR016C	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AACERI_AaceriADR021W	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AACERI_AaceriADR033W	COG0515	serine threonine protein kinase
AACERI_AaceriADR052W	COG1022	Amp-dependent synthetase and ligase
AACERI_AaceriADR053W	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AACERI_AaceriADR058C	COG0515	serine threonine protein kinase
AACERI_AaceriADR058C	COG2815	serine threonine protein kinase
AACERI_AaceriADR059C	COG4221	oxidoreductase activity
AACERI_AaceriADR083W	COG0459	protein refolding
AACERI_AaceriADR084C	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AACERI_AaceriADR086C	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AACERI_AaceriADR086C	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AACERI_AaceriADR087C	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AACERI_AaceriADR091W	COG2814	Major facilitator Superfamily
AACERI_AaceriADR102W	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
AACERI_AaceriADR111W	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AACERI_AaceriADR111W	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AACERI_AaceriADR115W	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AACERI_AaceriADR118C	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AACERI_AaceriADR118C	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AACERI_AaceriADR128C	COG0443	Heat shock 70 kDa protein
AACERI_AaceriADR132W	COG2132	Multicopper oxidase
AACERI_AaceriADR139C	COG2814	Major facilitator Superfamily
AACERI_AaceriADR140C	COG1643	Atp-dependent helicase
AACERI_AaceriADR152C	COG0039	L-malate dehydrogenase activity
AACERI_AaceriADR156C	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AACERI_AaceriADR160W	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AACERI_AaceriADR163W	COG0457	Tetratricopeptide repeat
AACERI_AaceriADR163W	COG0515	serine threonine protein kinase
AACERI_AaceriADR164C	COG3265	gluconokinase activity
AACERI_AaceriADR168C	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AACERI_AaceriADR174C	COG0515	serine threonine protein kinase
AACERI_AaceriADR188C	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AACERI_AaceriADR196W	COG2226	methyltransferase
AACERI_AaceriADR206W	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AACERI_AaceriADR208W	COG2857	Cytochrome c1
AACERI_AaceriADR208W	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AACERI_AaceriADR212C	COG1234	tRNA 3'-trailer cleavage
AACERI_AaceriADR219C	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AACERI_AaceriADR224W	COG1643	Atp-dependent helicase
AACERI_AaceriADR252W	COG0039	L-malate dehydrogenase activity
AACERI_AaceriADR253W	COG0515	serine threonine protein kinase
AACERI_AaceriADR254W	COG3961	Belongs to the TPP enzyme family
AACERI_AaceriADR262C	COG1252	NADH dehydrogenase
AACERI_AaceriADR269C	COG0681	Belongs to the peptidase S26 family
AACERI_AaceriADR287C	COG1643	Atp-dependent helicase
AACERI_AaceriADR288W	COG0572	uridine kinase
AACERI_AaceriADR290W	COG0070	glutamate synthase
AACERI_AaceriADR290W	COG0069	glutamate synthase activity
AACERI_AaceriADR290W	COG0067	glutamate synthase
AACERI_AaceriADR300C	COG4991	sh3 domain protein
AACERI_AaceriADR300C	COG3064	Membrane
AACERI_AaceriADR300C	COG0515	serine threonine protein kinase
AACERI_AaceriADR302W	COG0556	nucleotide-excision repair
AACERI_AaceriADR309W	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AACERI_AaceriADR312W	COG1253	flavin adenine dinucleotide binding
AACERI_AaceriADR313W	COG0515	serine threonine protein kinase
AACERI_AaceriADR317C	COG0515	serine threonine protein kinase
AACERI_AaceriADR317C	COG2815	serine threonine protein kinase
AACERI_AaceriADR327W	COG5434	Belongs to the glycosyl hydrolase 28 family
AACERI_AaceriADR351C	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AACERI_AaceriADR363C	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AACERI_AaceriADR368W	COG0469	pyruvate kinase activity
AACERI_AaceriADR369C	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AACERI_AaceriADR372C	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AACERI_AaceriADR373W	COG3266	domain, Protein
AACERI_AaceriADR373W	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AACERI_AaceriADR374C	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AACERI_AaceriADR396W	COG0509	glycine decarboxylation via glycine cleavage system
AACERI_AaceriADR402W	COG1160	GTP binding
AACERI_AaceriADR417W	COG1012	belongs to the aldehyde dehydrogenase family
AACERI_AaceriAEL013C	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AACERI_AaceriAEL019W	COG0165	Argininosuccinate lyase
AACERI_AaceriAEL020W	COG0017	Asparaginyl-tRNA synthetase
AACERI_AaceriAEL021C	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AACERI_AaceriAEL030W	COG0833	amino acid
AACERI_AaceriAEL031C	COG0557	exoribonuclease II activity
AACERI_AaceriAEL032W	COG0488	(ABC) transporter
AACERI_AaceriAEL034W	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AACERI_AaceriAEL042C	COG2814	Major facilitator Superfamily
AACERI_AaceriAEL044W	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AACERI_AaceriAEL054C	COG0017	Asparaginyl-tRNA synthetase
AACERI_AaceriAEL055C	COG0028	Belongs to the TPP enzyme family
AACERI_AaceriAEL057C	COG2814	Major facilitator Superfamily
AACERI_AaceriAEL062C	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AACERI_AaceriAEL065C	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AACERI_AaceriAEL076C	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AACERI_AaceriAEL078C	COG0200	Binds to the 23S rRNA
AACERI_AaceriAEL084W	COG0575	Belongs to the CDS family
AACERI_AaceriAEL086W	COG0513	Belongs to the DEAD box helicase family
AACERI_AaceriAEL087C	COG0482	sulfurtransferase activity
AACERI_AaceriAEL088C	COG0483	inositol monophosphate 1-phosphatase activity
AACERI_AaceriAEL095C	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AACERI_AaceriAEL097C	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AACERI_AaceriAEL098W	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AACERI_AaceriAEL112C	COG0484	heat shock protein binding
AACERI_AaceriAEL115C	COG0515	serine threonine protein kinase
AACERI_AaceriAEL119W	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AACERI_AaceriAEL120W	COG3266	domain, Protein
AACERI_AaceriAEL120W	COG0515	serine threonine protein kinase
AACERI_AaceriAEL122W	COG0142	geranyltranstransferase activity
AACERI_AaceriAEL124W	COG0481	GTPase activity
AACERI_AaceriAEL156W	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AACERI_AaceriAEL162W	COG0203	ribosomal protein L17
AACERI_AaceriAEL185C	COG0515	serine threonine protein kinase
AACERI_AaceriAEL188W	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AACERI_AaceriAEL191C	COG1999	signal sequence binding
AACERI_AaceriAEL192W	COG0012	GTP binding
AACERI_AaceriAEL196W	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AACERI_AaceriAEL198W	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AACERI_AaceriAEL208W	COG0205	6-phosphofructokinase activity
AACERI_AaceriAEL211W	COG0045	succinate-CoA ligase (ADP-forming) activity
AACERI_AaceriAEL215C	COG0363	glucosamine-6-phosphate deaminase activity
AACERI_AaceriAEL218W	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AACERI_AaceriAEL223C	COG0542	response to heat
AACERI_AaceriAEL229W	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AACERI_AaceriAEL235W	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AACERI_AaceriAEL238C	COG0142	geranyltranstransferase activity
AACERI_AaceriAEL244W	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AACERI_AaceriAEL256C	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AACERI_AaceriAEL257W	COG2119	membrane
AACERI_AaceriAEL259W	COG0175	sulfate reduction
AACERI_AaceriAEL265W	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AACERI_AaceriAEL294C	COG0672	)-iron permease
AACERI_AaceriAEL297W	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AACERI_AaceriAEL300C	COG0009	L-threonylcarbamoyladenylate synthase
AACERI_AaceriAEL305C	COG0028	Belongs to the TPP enzyme family
AACERI_AaceriAEL316W	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AACERI_AaceriAEL326C	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
AACERI_AaceriAEL337C	COG1196	nuclear chromosome segregation
AACERI_AaceriAEL338C	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AACERI_AaceriAEL338C	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
AACERI_AaceriAEL341W	COG0626	cystathionine gamma-synthase activity
AACERI_AaceriAEL343C	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AACERI_AaceriAER004W	COG0142	geranyltranstransferase activity
AACERI_AaceriAER007W	COG1012	belongs to the aldehyde dehydrogenase family
AACERI_AaceriAER014W	COG0135	phosphoribosylanthranilate isomerase activity
AACERI_AaceriAER015C	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AACERI_AaceriAER017C	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AACERI_AaceriAER033W	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AACERI_AaceriAER043C	COG0495	leucyl-tRNA aminoacylation
AACERI_AaceriAER044W	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AACERI_AaceriAER053C	COG1025	Belongs to the peptidase M16 family
AACERI_AaceriAER061C	COG0538	isocitrate dehydrogenase activity
AACERI_AaceriAER065C	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AACERI_AaceriAER070C	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AACERI_AaceriAER075W	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AACERI_AaceriAER083C	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AACERI_AaceriAER085C	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AACERI_AaceriAER091W	COG4178	(ABC) transporter
AACERI_AaceriAER094C	COG1643	Atp-dependent helicase
AACERI_AaceriAER098W	COG0418	dihydroorotase activity
AACERI_AaceriAER101W	COG1058	Belongs to the CinA family
AACERI_AaceriAER101W	COG1546	Belongs to the CinA family
AACERI_AaceriAER103W	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AACERI_AaceriAER105W	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AACERI_AaceriAER123W	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AACERI_AaceriAER128W	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AACERI_AaceriAER145W	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AACERI_AaceriAER169C	COG1222	aaa ATPase
AACERI_AaceriAER178W	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AACERI_AaceriAER187W	COG0443	Heat shock 70 kDa protein
AACERI_AaceriAER190W	COG1136	(ABC) transporter
AACERI_AaceriAER192W	COG1584	GPR1 FUN34 yaaH family protein
AACERI_AaceriAER195C	COG0515	serine threonine protein kinase
AACERI_AaceriAER195C	COG2815	serine threonine protein kinase
AACERI_AaceriAER218C	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AACERI_AaceriAER221W	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AACERI_AaceriAER223C	COG0515	serine threonine protein kinase
AACERI_AaceriAER226W	COG0351	phosphomethylpyrimidine kinase
AACERI_AaceriAER226W	COG0352	thiamine-phosphate diphosphorylase activity
AACERI_AaceriAER228C	COG0588	phosphoglycerate mutase activity
AACERI_AaceriAER230C	COG0137	argininosuccinate synthase activity
AACERI_AaceriAER233C	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AACERI_AaceriAER234W	COG0534	Mate efflux family protein
AACERI_AaceriAER239W	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AACERI_AaceriAER252C	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AACERI_AaceriAER254W	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AACERI_AaceriAER263C	COG4249	Peptidase C14 caspase catalytic subunit p20
AACERI_AaceriAER263C	COG2319	Wd-40 repeat
AACERI_AaceriAER267W	COG0512	Glutamine amidotransferase of anthranilate synthase
AACERI_AaceriAER267W	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AACERI_AaceriAER290C	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AACERI_AaceriAER292C	COG2072	flavoprotein involved in K transport
AACERI_AaceriAER294C	COG0148	phosphopyruvate hydratase activity
AACERI_AaceriAER298C	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AACERI_AaceriAER302C	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AACERI_AaceriAER308C	COG0025	NhaP-type Na H and K H
AACERI_AaceriAER312W	COG0450	alkyl hydroperoxide reductase
AACERI_AaceriAER321W	COG0277	FAD linked oxidase domain protein
AACERI_AaceriAER325W	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AACERI_AaceriAER327C	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AACERI_AaceriAER334C	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AACERI_AaceriAER341W	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AACERI_AaceriAER346W	COG0484	heat shock protein binding
AACERI_AaceriAER350W	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AACERI_AaceriAER350W	COG0519	Catalyzes the synthesis of GMP from XMP
AACERI_AaceriAER357C	COG1183	phosphatidylcholine synthase activity
AACERI_AaceriAER362W	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AACERI_AaceriAER363W	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AACERI_AaceriAER364W	COG0508	dehydrogenase complex catalyzes the overall conversion of
AACERI_AaceriAER375C	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AACERI_AaceriAER381C	COG0417	DNA replication proofreading
AACERI_AaceriAER386W	COG0477	Major facilitator Superfamily
AACERI_AaceriAER394W	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AACERI_AaceriAER401W	COG0656	L-ascorbic acid biosynthetic process
AACERI_AaceriAER405C	COG0833	amino acid
AACERI_AaceriAER407C	COG0572	uridine kinase
AACERI_AaceriAER410W	COG0187	DNA topoisomerase II activity
AACERI_AaceriAER415W	COG0459	protein refolding
AACERI_AaceriAER427W	COG0484	heat shock protein binding
AACERI_AaceriAER437C	COG0037	tRNA processing
AACERI_AaceriAER444W	COG2271	Major facilitator Superfamily
AACERI_AaceriAER451W	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AACERI_AaceriAFL011W	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AACERI_AaceriAFL027C	COG0513	Belongs to the DEAD box helicase family
AACERI_AaceriAFL032C	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AACERI_AaceriAFL032C	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AACERI_AaceriAFL034W	COG2814	Major facilitator Superfamily
AACERI_AaceriAFL039C	COG0386	Belongs to the glutathione peroxidase family
AACERI_AaceriAFL042C	COG1160	GTP binding
AACERI_AaceriAFL047W	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AACERI_AaceriAFL050W	COG0724	RNA recognition motif
AACERI_AaceriAFL057W	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AACERI_AaceriAFL060W	COG0489	protein tyrosine kinase activity
AACERI_AaceriAFL063W	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AACERI_AaceriAFL079W	COG3239	Fatty acid desaturase
AACERI_AaceriAFL080W	COG0513	Belongs to the DEAD box helicase family
AACERI_AaceriAFL081W	COG0531	amino acid
AACERI_AaceriAFL089C	COG0222	ribosome binding
AACERI_AaceriAFL090W	COG0515	serine threonine protein kinase
AACERI_AaceriAFL091W	COG0515	serine threonine protein kinase
AACERI_AaceriAFL102W	COG0513	Belongs to the DEAD box helicase family
AACERI_AaceriAFL105C	COG0101	tRNA pseudouridine synthase activity
AACERI_AaceriAFL117C	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AACERI_AaceriAFL121W	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AACERI_AaceriAFL123W	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AACERI_AaceriAFL130C	COG1058	Belongs to the CinA family
AACERI_AaceriAFL130C	COG1546	Belongs to the CinA family
AACERI_AaceriAFL131W	COG0488	(ABC) transporter
AACERI_AaceriAFL133C	COG0463	Glycosyl transferase, family 2
AACERI_AaceriAFL142W	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AACERI_AaceriAFL148C	COG0326	Molecular chaperone. Has ATPase activity
AACERI_AaceriAFL156W	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AACERI_AaceriAFL158C	COG2271	Major facilitator Superfamily
AACERI_AaceriAFL159W	COG0514	ATP-dependent DNA helicase (RecQ)
AACERI_AaceriAFL162C	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AACERI_AaceriAFL188C	COG2815	serine threonine protein kinase
AACERI_AaceriAFL188C	COG0515	serine threonine protein kinase
AACERI_AaceriAFL192C	COG4284	Utp--glucose-1-phosphate uridylyltransferase
AACERI_AaceriAFL197C	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AACERI_AaceriAFL201W	COG1012	belongs to the aldehyde dehydrogenase family
AACERI_AaceriAFL204C	COG2814	Major facilitator Superfamily
AACERI_AaceriAFL205C	COG2814	Major facilitator Superfamily
AACERI_AaceriAFL206C	COG0018	arginyl-trna synthetase
AACERI_AaceriAFL207C	COG0477	Major facilitator Superfamily
AACERI_AaceriAFL207C	COG2814	Major facilitator Superfamily
AACERI_AaceriAFL208C	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AACERI_AaceriAFL218C	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AACERI_AaceriAFL225W	COG0424	maF-like protein
AACERI_AaceriAFL229W	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AACERI_AaceriAFR001W	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AACERI_AaceriAFR012C	COG1612	heme a metabolic process
AACERI_AaceriAFR019W	COG0515	serine threonine protein kinase
AACERI_AaceriAFR022C	COG0688	phosphatidylethanolamine metabolic process
AACERI_AaceriAFR024C	COG0179	Fumarylacetoacetate (FAA) hydrolase
AACERI_AaceriAFR031C	COG0481	GTPase activity
AACERI_AaceriAFR035W	COG0515	serine threonine protein kinase
AACERI_AaceriAFR037W	COG0004	ammonium transporteR
AACERI_AaceriAFR051W	COG5277	cytoskeleton organization
AACERI_AaceriAFR052C	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AACERI_AaceriAFR062C	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AACERI_AaceriAFR067W	COG0459	protein refolding
AACERI_AaceriAFR076W	COG2815	serine threonine protein kinase
AACERI_AaceriAFR076W	COG0515	serine threonine protein kinase
AACERI_AaceriAFR084C	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AACERI_AaceriAFR085W	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AACERI_AaceriAFR093W	COG0210	DNA helicase
AACERI_AaceriAFR098W	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AACERI_AaceriAFR114W	COG0443	Heat shock 70 kDa protein
AACERI_AaceriAFR115W	COG1956	GAF domain-containing protein
AACERI_AaceriAFR119C	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AACERI_AaceriAFR129W	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AACERI_AaceriAFR133C	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AACERI_AaceriAFR134C	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AACERI_AaceriAFR137C	COG0473	3-isopropylmalate dehydrogenase activity
AACERI_AaceriAFR138W	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AACERI_AaceriAFR142C	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AACERI_AaceriAFR144W	COG1584	GPR1 FUN34 yaaH family protein
AACERI_AaceriAFR152C	COG1129	ABC transporter
AACERI_AaceriAFR155W	COG0459	protein refolding
AACERI_AaceriAFR156W	COG0833	amino acid
AACERI_AaceriAFR158W	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AACERI_AaceriAFR164W	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AACERI_AaceriAFR164W	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AACERI_AaceriAFR172C	COG0123	including yeast histone deacetylase and acetoin utilization protein
AACERI_AaceriAFR179C	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AACERI_AaceriAFR179C	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
AACERI_AaceriAFR183C	COG1233	COG1233 Phytoene dehydrogenase and related
AACERI_AaceriAFR213C	COG0138	bifunctional purine biosynthesis protein purh
AACERI_AaceriAFR220W	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AACERI_AaceriAFR222W	COG1643	Atp-dependent helicase
AACERI_AaceriAFR226C	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AACERI_AaceriAFR229C	COG2271	Major facilitator Superfamily
AACERI_AaceriAFR230C	COG0833	amino acid
AACERI_AaceriAFR232C	COG0488	(ABC) transporter
AACERI_AaceriAFR239W	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AACERI_AaceriAFR239W	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AACERI_AaceriAFR243C	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AACERI_AaceriAFR246C	COG0484	heat shock protein binding
AACERI_AaceriAFR254C	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AACERI_AaceriAFR255W	COG0445	tRNA wobble uridine modification
AACERI_AaceriAFR264W	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AACERI_AaceriAFR271W	COG0157	Belongs to the NadC ModD family
AACERI_AaceriAFR277W	COG0248	Ppx GppA phosphatase
AACERI_AaceriAFR282W	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AACERI_AaceriAFR292W	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AACERI_AaceriAFR295W	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AACERI_AaceriAFR303W	COG0367	asparagine synthase
AACERI_AaceriAFR322C	COG2814	Major facilitator Superfamily
AACERI_AaceriAFR334W	COG0612	Peptidase, M16
AACERI_AaceriAFR352C	COG0443	Heat shock 70 kDa protein
AACERI_AaceriAFR354C	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AACERI_AaceriAFR359C	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
AACERI_AaceriAFR360W	COG3474	cytochrome
AACERI_AaceriAFR361C	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AACERI_AaceriAFR367W	COG1053	succinate dehydrogenase
AACERI_AaceriAFR369W	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AACERI_AaceriAFR376W	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AACERI_AaceriAFR377C	COG0515	serine threonine protein kinase
AACERI_AaceriAFR394W	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AACERI_AaceriAFR403W	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AACERI_AaceriAFR404C	COG0085	RNA polymerase activity
AACERI_AaceriAFR410W	COG0646	methionine synthase
AACERI_AaceriAFR410W	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AACERI_AaceriAFR412C	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AACERI_AaceriAFR418W	COG0459	protein refolding
AACERI_AaceriAFR422W	COG2255	four-way junction helicase activity
AACERI_AaceriAFR425C	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AACERI_AaceriAFR432W	COG1132	(ABC) transporter
AACERI_AaceriAFR442C	COG0477	Major facilitator Superfamily
AACERI_AaceriAFR445C	COG0193	aminoacyl-tRNA hydrolase activity
AACERI_AaceriAFR447C	COG1252	NADH dehydrogenase
AACERI_AaceriAFR457W	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AACERI_AaceriAFR466C	COG1335	isochorismatase
AACERI_AaceriAFR485C	COG0133	tryptophan synthase activity
AACERI_AaceriAFR493C	COG0590	tRNA wobble adenosine to inosine editing
AACERI_AaceriAFR512W	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AACERI_AaceriAFR516W	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AACERI_AaceriAFR529W	COG1621	beta-fructofuranosidase activity
AACERI_AaceriAFR534W	COG0505	Belongs to the CarA family
AACERI_AaceriAFR538C	COG0571	ribonuclease III activity
AACERI_AaceriAFR544W	COG0517	IMP dehydrogenase activity
AACERI_AaceriAFR544W	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AACERI_AaceriAFR547W	COG0058	SHG alpha-glucan phosphorylase activity
AACERI_AaceriAFR548C	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AACERI_AaceriAFR554W	COG0406	alpha-ribazole phosphatase activity
AACERI_AaceriAFR555W	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AACERI_AaceriAFR561W	COG4221	oxidoreductase activity
AACERI_AaceriAFR573C	COG0047	phosphoribosylformylglycinamidine synthase activity
AACERI_AaceriAFR573C	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AACERI_AaceriAFR583W	COG0443	Heat shock 70 kDa protein
AACERI_AaceriAFR592W	COG0204	Acyl-transferase
AACERI_AaceriAFR593C	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AACERI_AaceriAFR598C	COG1953	Uracil, thiamine, allantoin
AACERI_AaceriAFR599W	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AACERI_AaceriAFR602W	COG2814	Major facilitator Superfamily
AACERI_AaceriAFR603C	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AACERI_AaceriAFR609C	COG0095	Lipoate-protein ligase
AACERI_AaceriAFR622W	COG2233	PERMEase
AACERI_AaceriAFR626W	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AACERI_AaceriAFR629W	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AACERI_AaceriAFR637W	COG1196	nuclear chromosome segregation
AACERI_AaceriAFR639W	COG0484	heat shock protein binding
AACERI_AaceriAFR640W	COG0215	cysteine-tRNA ligase activity
AACERI_AaceriAFR647C	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AACERI_AaceriAFR648W	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AACERI_AaceriAFR650W	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AACERI_AaceriAFR667C	COG0833	amino acid
AACERI_AaceriAFR668W	COG0833	amino acid
AACERI_AaceriAFR675W	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AACERI_AaceriAFR681W	COG1819	glycosyl
AACERI_AaceriAFR682C	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AACERI_AaceriAFR683C	COG1132	(ABC) transporter
AACERI_AaceriAFR696C	COG2815	serine threonine protein kinase
AACERI_AaceriAFR696C	COG0515	serine threonine protein kinase
AACERI_AaceriAFR698C	COG0833	amino acid
AACERI_AaceriAFR703W	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AACERI_AaceriAFR718W	COG3118	belongs to the thioredoxin family
AACERI_AaceriAFR721W	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AACERI_AaceriAFR734C	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AACERI_AaceriAFR735W	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AACERI_AaceriAFR738C	COG0038	chloride channel
AACERI_AaceriAGL003W	COG0101	tRNA pseudouridine synthase activity
AACERI_AaceriAGL004C	COG0513	Belongs to the DEAD box helicase family
AACERI_AaceriAGL013W	COG0228	four-way junction DNA binding
AACERI_AaceriAGL018C	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AACERI_AaceriAGL023W	COG1196	nuclear chromosome segregation
AACERI_AaceriAGL026W	COG2271	Major facilitator Superfamily
AACERI_AaceriAGL033C	COG0316	Belongs to the HesB IscA family
AACERI_AaceriAGL041C	COG2217	Heavy metal translocating P-type atpase
AACERI_AaceriAGL043C	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AACERI_AaceriAGL050C	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AACERI_AaceriAGL053C	COG0217	transcriptional regulatory protein
AACERI_AaceriAGL060W	COG1028	Short-chain dehydrogenase reductase Sdr
AACERI_AaceriAGL066W	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AACERI_AaceriAGL068W	COG0281	malic enzyme
AACERI_AaceriAGL069C	COG2814	Major facilitator Superfamily
AACERI_AaceriAGL080C	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AACERI_AaceriAGL085C	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AACERI_AaceriAGL092W	COG0459	protein refolding
AACERI_AaceriAGL097C	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AACERI_AaceriAGL098W	COG3844	kynureninase activity
AACERI_AaceriAGL101C	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AACERI_AaceriAGL101C	COG0551	DNA topoisomerase type I activity
AACERI_AaceriAGL107W	COG0321	lipoyl(octanoyl) transferase activity
AACERI_AaceriAGL110C	COG0237	dephospho-CoA kinase activity
AACERI_AaceriAGL112C	COG0513	Belongs to the DEAD box helicase family
AACERI_AaceriAGL122W	COG0024	Methionine aminopeptidase
AACERI_AaceriAGL171W	COG0833	amino acid
AACERI_AaceriAGL177C	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AACERI_AaceriAGL186C	COG2890	protein-(glutamine-N5) methyltransferase activity
AACERI_AaceriAGL200W	COG0508	dehydrogenase complex catalyzes the overall conversion of
AACERI_AaceriAGL201C	COG0149	triose-phosphate isomerase activity
AACERI_AaceriAGL210C	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AACERI_AaceriAGL222W	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AACERI_AaceriAGL224W	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AACERI_AaceriAGL225C	COG0513	Belongs to the DEAD box helicase family
AACERI_AaceriAGL229C	COG3118	belongs to the thioredoxin family
AACERI_AaceriAGL231W	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AACERI_AaceriAGL247C	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AACERI_AaceriAGL249C	COG0515	serine threonine protein kinase
AACERI_AaceriAGL250W	COG0724	RNA recognition motif
AACERI_AaceriAGL260W	COG1785	Belongs to the alkaline phosphatase family
AACERI_AaceriAGL261W	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AACERI_AaceriAGL272C	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AACERI_AaceriAGL276W	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AACERI_AaceriAGL277W	COG2814	Major facilitator Superfamily
AACERI_AaceriAGL283W	COG0024	Methionine aminopeptidase
AACERI_AaceriAGL303W	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AACERI_AaceriAGL320C	COG0504	CTP synthase activity
AACERI_AaceriAGL335W	COG5265	(ABC) transporter
AACERI_AaceriAGL346W	COG1132	(ABC) transporter
AACERI_AaceriAGR010C	COG0724	RNA recognition motif
AACERI_AaceriAGR021C	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AACERI_AaceriAGR022C	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AACERI_AaceriAGR024C	COG1024	Enoyl-CoA hydratase
AACERI_AaceriAGR027C	COG0515	serine threonine protein kinase
AACERI_AaceriAGR027C	COG2815	serine threonine protein kinase
AACERI_AaceriAGR030C	COG0408	coproporphyrinogen oxidase activity
AACERI_AaceriAGR035C	COG0051	transcription antitermination factor activity, RNA binding
AACERI_AaceriAGR037C	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AACERI_AaceriAGR038C	COG0833	amino acid
AACERI_AaceriAGR039C	COG0833	amino acid
AACERI_AaceriAGR040C	COG0833	amino acid
AACERI_AaceriAGR047W	COG1132	(ABC) transporter
AACERI_AaceriAGR048C	COG0515	serine threonine protein kinase
AACERI_AaceriAGR048C	COG2815	serine threonine protein kinase
AACERI_AaceriAGR058W	COG2815	serine threonine protein kinase
AACERI_AaceriAGR058W	COG0515	serine threonine protein kinase
AACERI_AaceriAGR066W	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AACERI_AaceriAGR074C	COG0714	Associated with various cellular activities
AACERI_AaceriAGR076C	COG0477	Major facilitator Superfamily
AACERI_AaceriAGR080W	COG0081	regulation of translation
AACERI_AaceriAGR081C	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AACERI_AaceriAGR084C	COG0484	heat shock protein binding
AACERI_AaceriAGR089C	COG1196	nuclear chromosome segregation
AACERI_AaceriAGR103W	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AACERI_AaceriAGR111W	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AACERI_AaceriAGR115C	COG0563	adenylate kinase activity
AACERI_AaceriAGR116W	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AACERI_AaceriAGR118W	COG0617	tRNA 3'-terminal CCA addition
AACERI_AaceriAGR127C	COG0156	8-amino-7-oxononanoate synthase activity
AACERI_AaceriAGR129C	COG0672	)-iron permease
AACERI_AaceriAGR141C	COG0436	Aminotransferase
AACERI_AaceriAGR143W	COG0706	membrane insertase activity
AACERI_AaceriAGR164C	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AACERI_AaceriAGR165W	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AACERI_AaceriAGR167W	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AACERI_AaceriAGR169W	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AACERI_AaceriAGR192C	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AACERI_AaceriAGR194W	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AACERI_AaceriAGR196W	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AACERI_AaceriAGR206C	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AACERI_AaceriAGR231C	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AACERI_AaceriAGR236W	COG1196	nuclear chromosome segregation
AACERI_AaceriAGR249C	COG0756	dUTP diphosphatase activity
AACERI_AaceriAGR259C	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AACERI_AaceriAGR272W	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AACERI_AaceriAGR278C	COG0513	Belongs to the DEAD box helicase family
AACERI_AaceriAGR279C	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AACERI_AaceriAGR281C	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AACERI_AaceriAGR288W	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AACERI_AaceriAGR290W	COG0481	GTPase activity
AACERI_AaceriAGR297C	COG0647	UMP catabolic process
AACERI_AaceriAGR298C	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AACERI_AaceriAGR298C	COG1648	precorrin-2 dehydrogenase activity
AACERI_AaceriAGR319W	COG0833	amino acid
AACERI_AaceriAGR320W	COG1185	polyribonucleotide nucleotidyltransferase activity
AACERI_AaceriAGR322W	COG0529	Catalyzes the synthesis of activated sulfate
AACERI_AaceriAGR322W	COG2046	Belongs to the sulfate adenylyltransferase family
AACERI_AaceriAGR323C	COG0508	dehydrogenase complex catalyzes the overall conversion of
AACERI_AaceriAGR329C	COG1902	pentaerythritol trinitrate reductase activity
AACERI_AaceriAGR332C	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AACERI_AaceriAGR332C	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AACERI_AaceriAGR335C	COG0302	gtp cyclohydrolase
AACERI_AaceriAGR346C	COG1444	tRNA N-acetyltransferase activity
AACERI_AaceriAGR368W	COG0450	alkyl hydroperoxide reductase
AACERI_AaceriAGR371C	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AACERI_AaceriAGR379W	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AACERI_AaceriAGR387C	COG1965	Belongs to the frataxin family
AACERI_AaceriAGR395W	COG0123	including yeast histone deacetylase and acetoin utilization protein
AACERI_AaceriAGR396W	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AACERI_AaceriAGR403W	COG0673	inositol 2-dehydrogenase activity
AACERI_AaceriAGR405C	COG0339	signal peptide processing
AACERI_AaceriAGR406C	COG0339	signal peptide processing