Astex_1246 f66f8a0b3a1979ceb1af2dccd3c42482 284 SMART SM01057 61 282 4.8E-77 T 13-10-2018 IPR001148 Alpha carbonic anhydrase domain Astex_1246 f66f8a0b3a1979ceb1af2dccd3c42482 284 SUPERFAMILY SSF51069 59 278 6.8E-69 T 13-10-2018 IPR036398 Alpha carbonic anhydrase domain superfamily Astex_1246 f66f8a0b3a1979ceb1af2dccd3c42482 284 Gene3D G3DSA:3.10.200.10 58 283 8.9E-72 T 13-10-2018 IPR036398 Alpha carbonic anhydrase domain superfamily Astex_1246 f66f8a0b3a1979ceb1af2dccd3c42482 284 Pfam PF00194 Eukaryotic-type carbonic anhydrase 60 279 7.0E-42 T 13-10-2018 IPR001148 Alpha carbonic anhydrase domain Astex_3258 c60303a7140c693e40467c4a47ba5b21 946 Pfam PF07516 SecA Wing and Scaffold domain 656 867 3.5E-60 T 13-10-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 Astex_3258 c60303a7140c693e40467c4a47ba5b21 946 PRINTS PR00906 SecA protein signature 116 126 7.9E-66 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Astex_3258 c60303a7140c693e40467c4a47ba5b21 946 PRINTS PR00906 SecA protein signature 403 416 7.9E-66 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Astex_3258 c60303a7140c693e40467c4a47ba5b21 946 PRINTS PR00906 SecA protein signature 62 86 7.9E-66 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Astex_3258 c60303a7140c693e40467c4a47ba5b21 946 PRINTS PR00906 SecA protein signature 329 351 7.9E-66 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Astex_3258 c60303a7140c693e40467c4a47ba5b21 946 PRINTS PR00906 SecA protein signature 366 383 7.9E-66 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Astex_3258 c60303a7140c693e40467c4a47ba5b21 946 PRINTS PR00906 SecA protein signature 169 189 7.9E-66 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Astex_3258 c60303a7140c693e40467c4a47ba5b21 946 PRINTS PR00906 SecA protein signature 100 114 7.9E-66 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Astex_3258 c60303a7140c693e40467c4a47ba5b21 946 SUPERFAMILY SSF52540 406 657 3.09E-49 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_3258 c60303a7140c693e40467c4a47ba5b21 946 SUPERFAMILY SSF52540 5 405 4.5E-76 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_3258 c60303a7140c693e40467c4a47ba5b21 946 Gene3D G3DSA:3.10.450.50 905 946 7.9E-6 T 13-10-2018 Astex_3258 c60303a7140c693e40467c4a47ba5b21 946 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 27 463 3.9E-194 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Astex_3258 c60303a7140c693e40467c4a47ba5b21 946 SMART SM00958 227 348 1.8E-65 T 13-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 Astex_3258 c60303a7140c693e40467c4a47ba5b21 946 Pfam PF07517 SecA DEAD-like domain 6 391 1.4E-127 T 13-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 Astex_3258 c60303a7140c693e40467c4a47ba5b21 946 Pfam PF01043 SecA preprotein cross-linking domain 231 348 7.8E-34 T 13-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 Astex_3258 c60303a7140c693e40467c4a47ba5b21 946 Gene3D G3DSA:3.90.1440.10 228 358 4.3E-169 T 13-10-2018 Astex_3258 c60303a7140c693e40467c4a47ba5b21 946 SUPERFAMILY SSF81886 659 934 9.29E-76 T 13-10-2018 IPR036266 SecA, Wing/Scaffold superfamily Astex_3258 c60303a7140c693e40467c4a47ba5b21 946 Gene3D G3DSA:3.40.50.300 24 405 4.3E-169 T 13-10-2018 Astex_3258 c60303a7140c693e40467c4a47ba5b21 946 Pfam PF02810 SEC-C motif 926 943 1.4E-8 T 13-10-2018 IPR004027 SEC-C motif Astex_3258 c60303a7140c693e40467c4a47ba5b21 946 ProSitePatterns PS01312 SecA family signature. 527 542 - T 13-10-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 Astex_3258 c60303a7140c693e40467c4a47ba5b21 946 Gene3D G3DSA:1.10.3060.10 660 871 1.6E-67 T 13-10-2018 Astex_3258 c60303a7140c693e40467c4a47ba5b21 946 SUPERFAMILY SSF81767 226 358 2.22E-39 T 13-10-2018 IPR036670 SecA, preprotein cross-linking domain superfamily GO:0016020|GO:0017038 Astex_3258 c60303a7140c693e40467c4a47ba5b21 946 Hamap MF_01382 Protein translocase subunit SecA [secA]. 4 870 19.638 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 Astex_3258 c60303a7140c693e40467c4a47ba5b21 946 SMART SM00957 5 392 8.8E-276 T 13-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 Astex_2713 38f7fa8b14b57b24d4fcbe5a84189847 446 TIGRFAM TIGR00115 tig: trigger factor 12 424 5.0E-122 T 13-10-2018 IPR005215 Trigger factor GO:0015031 Astex_2713 38f7fa8b14b57b24d4fcbe5a84189847 446 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 269 425 1.7E-40 T 13-10-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 Astex_2713 38f7fa8b14b57b24d4fcbe5a84189847 446 PIRSF PIRSF003095 1 446 4.4E-115 T 13-10-2018 IPR005215 Trigger factor GO:0015031 Astex_2713 38f7fa8b14b57b24d4fcbe5a84189847 446 Hamap MF_00303 Trigger factor [tig]. 1 431 19.649 T 13-10-2018 IPR005215 Trigger factor GO:0015031 Astex_2713 38f7fa8b14b57b24d4fcbe5a84189847 446 SUPERFAMILY SSF109998 257 440 5.69E-42 T 13-10-2018 IPR027304 Trigger factor/SurA domain superfamily Astex_2713 38f7fa8b14b57b24d4fcbe5a84189847 446 Pfam PF05697 Bacterial trigger factor protein (TF) 1 149 1.5E-34 T 13-10-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 Astex_2713 38f7fa8b14b57b24d4fcbe5a84189847 446 SUPERFAMILY SSF102735 1 136 6.8E-32 T 13-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 Astex_2713 38f7fa8b14b57b24d4fcbe5a84189847 446 SUPERFAMILY SSF54534 106 248 1.73E-32 T 13-10-2018 Astex_2713 38f7fa8b14b57b24d4fcbe5a84189847 446 Gene3D G3DSA:1.10.3120.10 121 430 5.9E-83 T 13-10-2018 IPR037041 Trigger factor, C-terminal domain superfamily GO:0006457|GO:0015031 Astex_2713 38f7fa8b14b57b24d4fcbe5a84189847 446 Gene3D G3DSA:3.10.50.40 155 254 5.9E-83 T 13-10-2018 Astex_2713 38f7fa8b14b57b24d4fcbe5a84189847 446 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 165 238 2.4E-15 T 13-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain Astex_2713 38f7fa8b14b57b24d4fcbe5a84189847 446 Gene3D G3DSA:3.30.70.1050 1 120 2.6E-29 T 13-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 Astex_2727 e15945725f50eda86a28da9ac3ca64b6 762 Gene3D G3DSA:3.30.2080.10 312 747 2.5E-232 T 13-10-2018 Astex_2727 e15945725f50eda86a28da9ac3ca64b6 762 Gene3D G3DSA:1.20.1050.60 366 455 2.5E-232 T 13-10-2018 Astex_2727 e15945725f50eda86a28da9ac3ca64b6 762 Gene3D G3DSA:1.20.1610.10 456 619 2.5E-232 T 13-10-2018 Astex_2727 e15945725f50eda86a28da9ac3ca64b6 762 Pfam PF07971 Glycosyl hydrolase family 92 254 743 3.1E-158 T 13-10-2018 IPR012939 Glycosyl hydrolase family 92 Astex_2727 e15945725f50eda86a28da9ac3ca64b6 762 SUPERFAMILY SSF48208 273 718 2.89E-23 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 Astex_2727 e15945725f50eda86a28da9ac3ca64b6 762 Gene3D G3DSA:2.70.98.10 31 365 2.5E-232 T 13-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 Astex_2727 e15945725f50eda86a28da9ac3ca64b6 762 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 23 747 2.4E-187 T 13-10-2018 IPR005887 Alpha-1,2-mannosidase, putative Astex_2075 4a4108a20924460f475cd708fb5fda2a 367 Gene3D G3DSA:1.10.3290.10 41 291 7.2E-44 T 13-10-2018 IPR036597 Fido-like domain superfamily Astex_2075 4a4108a20924460f475cd708fb5fda2a 367 SUPERFAMILY SSF140931 94 294 8.11E-38 T 13-10-2018 IPR036597 Fido-like domain superfamily Astex_2075 4a4108a20924460f475cd708fb5fda2a 367 Pfam PF13776 Domain of unknown function (DUF4172) 3 84 2.0E-32 T 13-10-2018 IPR025230 Domain of unknown function DUF4172 Astex_2075 4a4108a20924460f475cd708fb5fda2a 367 Pfam PF02661 Fic/DOC family 113 223 1.1E-18 T 13-10-2018 IPR003812 Fido domain Astex_2014 0766de78afb7cde2fa0c39eeb6cb8616 656 TIGRFAM TIGR00353 nrfE: cytochrome c-type biogenesis protein CcmF 53 646 4.3E-174 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 Astex_2014 0766de78afb7cde2fa0c39eeb6cb8616 656 Pfam PF01578 Cytochrome C assembly protein 89 295 1.6E-49 T 13-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 Astex_2014 0766de78afb7cde2fa0c39eeb6cb8616 656 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 132 149 1.9E-82 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 Astex_2014 0766de78afb7cde2fa0c39eeb6cb8616 656 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 294 310 1.9E-82 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 Astex_2014 0766de78afb7cde2fa0c39eeb6cb8616 656 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 274 294 1.9E-82 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 Astex_2014 0766de78afb7cde2fa0c39eeb6cb8616 656 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 80 106 1.9E-82 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 Astex_2014 0766de78afb7cde2fa0c39eeb6cb8616 656 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 210 236 1.9E-82 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 Astex_2014 0766de78afb7cde2fa0c39eeb6cb8616 656 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 244 264 1.9E-82 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 Astex_2014 0766de78afb7cde2fa0c39eeb6cb8616 656 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 310 329 1.9E-82 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 Astex_2014 0766de78afb7cde2fa0c39eeb6cb8616 656 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 159 181 1.9E-82 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 Astex_2014 0766de78afb7cde2fa0c39eeb6cb8616 656 Pfam PF16327 Cytochrome c-type biogenesis protein CcmF C-terminal 315 643 5.6E-94 T 13-10-2018 IPR032523 Cytochrome c-type biogenesis protein CcmF, C-terminal Astex_2014 0766de78afb7cde2fa0c39eeb6cb8616 656 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 4 28 9.0E-36 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 Astex_2014 0766de78afb7cde2fa0c39eeb6cb8616 656 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 351 368 9.0E-36 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 Astex_2014 0766de78afb7cde2fa0c39eeb6cb8616 656 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 313 328 9.0E-36 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 Astex_2014 0766de78afb7cde2fa0c39eeb6cb8616 656 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 636 649 9.0E-36 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 Astex_2014 0766de78afb7cde2fa0c39eeb6cb8616 656 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 113 136 9.0E-36 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 Astex_2014 0766de78afb7cde2fa0c39eeb6cb8616 656 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 394 413 9.0E-36 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 Astex_2014 0766de78afb7cde2fa0c39eeb6cb8616 656 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 189 204 9.0E-36 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 Astex_3394 459872698d85360f598c296d13a6df17 456 SUPERFAMILY SSF89550 25 318 8.63E-17 T 13-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 Astex_1192 5d1bc59baee3708c1e6b1a5a15fb85d2 175 Pfam PF13505 Outer membrane protein beta-barrel domain 9 175 6.0E-23 T 13-10-2018 IPR027385 Outer membrane protein beta-barrel Astex_1192 5d1bc59baee3708c1e6b1a5a15fb85d2 175 Gene3D G3DSA:2.40.160.20 12 175 6.1E-15 T 13-10-2018 Astex_1192 5d1bc59baee3708c1e6b1a5a15fb85d2 175 SUPERFAMILY SSF56925 32 169 1.33E-13 T 13-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel Astex_3230 b4361160d7ae3b6c79beeadcc3990da3 241 ProSitePatterns PS00018 EF-hand calcium-binding domain. 199 211 - T 13-10-2018 IPR018247 EF-Hand 1, calcium-binding site Astex_3230 b4361160d7ae3b6c79beeadcc3990da3 241 Pfam PF13202 EF hand 195 211 1.9E-4 T 13-10-2018 IPR002048 EF-hand domain GO:0005509 Astex_3230 b4361160d7ae3b6c79beeadcc3990da3 241 SUPERFAMILY SSF47473 68 211 3.56E-11 T 13-10-2018 IPR011992 EF-hand domain pair Astex_2009 243f398869c130045c14e16571bdc99f 132 SUPERFAMILY SSF46894 62 131 5.78E-21 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Astex_2009 243f398869c130045c14e16571bdc99f 132 ProSitePatterns PS00622 LuxR-type HTH domain signature. 85 112 - T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Astex_2009 243f398869c130045c14e16571bdc99f 132 Pfam PF00196 Bacterial regulatory proteins, luxR family 72 125 2.5E-19 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Astex_2009 243f398869c130045c14e16571bdc99f 132 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 101 113 3.9E-13 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Astex_2009 243f398869c130045c14e16571bdc99f 132 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 71 85 3.9E-13 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Astex_2009 243f398869c130045c14e16571bdc99f 132 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 85 101 3.9E-13 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Astex_2009 243f398869c130045c14e16571bdc99f 132 SMART SM00421 68 125 5.0E-22 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Astex_2009 243f398869c130045c14e16571bdc99f 132 Gene3D G3DSA:1.10.10.10 24 132 4.2E-24 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_3288 d5b6f69cd023fb565ca16204ffb8c198 405 SUPERFAMILY SSF103473 15 395 4.45E-53 T 13-10-2018 IPR036259 MFS transporter superfamily Astex_3288 d5b6f69cd023fb565ca16204ffb8c198 405 Pfam PF07690 Major Facilitator Superfamily 20 361 1.4E-34 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Astex_3288 d5b6f69cd023fb565ca16204ffb8c198 405 Gene3D G3DSA:1.20.1720.10 15 395 2.8E-82 T 13-10-2018 Astex_3288 d5b6f69cd023fb565ca16204ffb8c198 405 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 26 377 1.4E-62 T 13-10-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0006855|GO:0015238|GO:0016021 Astex_2951 941d22599fe131bb52caa90e7517abc0 169 SUPERFAMILY SSF50475 5 163 1.4E-29 T 13-10-2018 Astex_2951 941d22599fe131bb52caa90e7517abc0 169 Pfam PF01613 Flavin reductase like domain 14 164 5.8E-25 T 13-10-2018 IPR002563 Flavin reductase like domain GO:0010181 Astex_2951 941d22599fe131bb52caa90e7517abc0 169 Gene3D G3DSA:2.30.110.10 2 166 3.0E-36 T 13-10-2018 IPR012349 FMN-binding split barrel GO:0048037 Astex_2951 941d22599fe131bb52caa90e7517abc0 169 SMART SM00903 13 163 1.5E-38 T 13-10-2018 IPR002563 Flavin reductase like domain GO:0010181 Astex_0387 39920b2cacec86a0863134ead2150c55 406 Gene3D G3DSA:3.90.105.10 23 176 1.7E-106 T 13-10-2018 Astex_0387 39920b2cacec86a0863134ead2150c55 406 Gene3D G3DSA:3.40.980.10 177 327 1.7E-106 T 13-10-2018 IPR036425 MoaB/Mog-like domain superfamily Astex_0387 39920b2cacec86a0863134ead2150c55 406 SUPERFAMILY SSF53218 177 322 4.19E-34 T 13-10-2018 IPR036425 MoaB/Mog-like domain superfamily Astex_0387 39920b2cacec86a0863134ead2150c55 406 Pfam PF00994 Probable molybdopterin binding domain 183 318 1.7E-20 T 13-10-2018 IPR001453 MoaB/Mog domain Astex_0387 39920b2cacec86a0863134ead2150c55 406 Gene3D G3DSA:2.170.190.11 47 143 1.7E-106 T 13-10-2018 Astex_0387 39920b2cacec86a0863134ead2150c55 406 SMART SM00852 182 319 6.9E-34 T 13-10-2018 IPR001453 MoaB/Mog domain Astex_0387 39920b2cacec86a0863134ead2150c55 406 SUPERFAMILY SSF63867 332 404 3.79E-10 T 13-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Astex_0387 39920b2cacec86a0863134ead2150c55 406 Gene3D G3DSA:2.40.340.10 328 396 1.7E-106 T 13-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Astex_0387 39920b2cacec86a0863134ead2150c55 406 Pfam PF03454 MoeA C-terminal region (domain IV) 332 399 6.4E-9 T 13-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Astex_0387 39920b2cacec86a0863134ead2150c55 406 Pfam PF03453 MoeA N-terminal region (domain I and II) 5 169 1.5E-39 T 13-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Astex_0387 39920b2cacec86a0863134ead2150c55 406 SUPERFAMILY SSF63882 5 178 9.16E-44 T 13-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Astex_2968 df2ae42f8fd2de47d4f201eeb96c545c 322 SUPERFAMILY SSF103481 53 159 1.44E-9 T 13-10-2018 Astex_2968 df2ae42f8fd2de47d4f201eeb96c545c 322 Pfam PF00892 EamA-like transporter family 169 303 6.2E-15 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Astex_2968 df2ae42f8fd2de47d4f201eeb96c545c 322 Pfam PF00892 EamA-like transporter family 18 156 3.0E-13 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Astex_2968 df2ae42f8fd2de47d4f201eeb96c545c 322 SUPERFAMILY SSF103481 227 308 1.83E-11 T 13-10-2018 Astex_2970 8ac0fe24113331c1318105ac1693c6e8 189 Pfam PF01936 NYN domain 8 165 1.6E-37 T 13-10-2018 IPR021139 NYN domain, limkain-b1-type Astex_2970 8ac0fe24113331c1318105ac1693c6e8 189 Gene3D G3DSA:3.40.50.1010 3 169 7.1E-50 T 13-10-2018 Astex_3150 4abd7afdc0d75be3201ddd3fe133e24b 208 Gene3D G3DSA:3.40.50.1240 1 185 2.9E-48 T 13-10-2018 IPR029033 Histidine phosphatase superfamily Astex_3150 4abd7afdc0d75be3201ddd3fe133e24b 208 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 4 13 - T 13-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 Astex_3150 4abd7afdc0d75be3201ddd3fe133e24b 208 PIRSF PIRSF000709 1 131 4.5E-6 T 13-10-2018 Astex_3150 4abd7afdc0d75be3201ddd3fe133e24b 208 SUPERFAMILY SSF53254 2 185 4.24E-45 T 13-10-2018 IPR029033 Histidine phosphatase superfamily Astex_3150 4abd7afdc0d75be3201ddd3fe133e24b 208 SMART SM00855 1 156 2.2E-19 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 Astex_3150 4abd7afdc0d75be3201ddd3fe133e24b 208 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 174 3.5E-43 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 Astex_0001 61b51d70f6e4471620f905b09b908e04 473 SMART SM00382 163 291 1.2E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_0001 61b51d70f6e4471620f905b09b908e04 473 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 382 450 1.0E-28 T 13-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 Astex_0001 61b51d70f6e4471620f905b09b908e04 473 Pfam PF00308 Bacterial dnaA protein 131 352 1.2E-80 T 13-10-2018 IPR013317 Chromosomal replication initiator protein DnaA Astex_0001 61b51d70f6e4471620f905b09b908e04 473 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 13 472 27.474 T 13-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 Astex_0001 61b51d70f6e4471620f905b09b908e04 473 Gene3D G3DSA:3.40.50.300 120 294 2.1E-43 T 13-10-2018 Astex_0001 61b51d70f6e4471620f905b09b908e04 473 Gene3D G3DSA:1.10.8.60 297 373 8.0E-7 T 13-10-2018 Astex_0001 61b51d70f6e4471620f905b09b908e04 473 ProSitePatterns PS01008 DnaA protein signature. 431 450 - T 13-10-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 Astex_0001 61b51d70f6e4471620f905b09b908e04 473 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 196 210 1.3E-41 T 13-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like Astex_0001 61b51d70f6e4471620f905b09b908e04 473 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 262 289 1.3E-41 T 13-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like Astex_0001 61b51d70f6e4471620f905b09b908e04 473 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 228 242 1.3E-41 T 13-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like Astex_0001 61b51d70f6e4471620f905b09b908e04 473 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 164 184 1.3E-41 T 13-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like Astex_0001 61b51d70f6e4471620f905b09b908e04 473 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 431 450 1.3E-41 T 13-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like Astex_0001 61b51d70f6e4471620f905b09b908e04 473 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 16 471 2.4E-133 T 13-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 Astex_0001 61b51d70f6e4471620f905b09b908e04 473 SMART SM00760 381 450 1.2E-39 T 13-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 Astex_0001 61b51d70f6e4471620f905b09b908e04 473 Gene3D G3DSA:1.10.1750.10 380 473 3.3E-35 T 13-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 Astex_0001 61b51d70f6e4471620f905b09b908e04 473 SUPERFAMILY SSF52540 131 348 5.02E-37 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0001 61b51d70f6e4471620f905b09b908e04 473 SUPERFAMILY SSF48295 372 472 4.97E-36 T 13-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 Astex_3856 c0180bf62c05201223624f44af85d53c 1063 Gene3D G3DSA:1.20.1640.10 13 517 1.0E-292 T 13-10-2018 Astex_3856 c0180bf62c05201223624f44af85d53c 1063 PRINTS PR00702 Acriflavin resistance protein family signature 366 387 9.6E-24 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3856 c0180bf62c05201223624f44af85d53c 1063 PRINTS PR00702 Acriflavin resistance protein family signature 480 503 9.6E-24 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3856 c0180bf62c05201223624f44af85d53c 1063 PRINTS PR00702 Acriflavin resistance protein family signature 553 570 9.6E-24 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3856 c0180bf62c05201223624f44af85d53c 1063 PRINTS PR00702 Acriflavin resistance protein family signature 339 362 9.6E-24 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3856 c0180bf62c05201223624f44af85d53c 1063 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 9.6E-24 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3856 c0180bf62c05201223624f44af85d53c 1063 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 9.6E-24 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3856 c0180bf62c05201223624f44af85d53c 1063 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1050 0.0 T 13-10-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 Astex_3856 c0180bf62c05201223624f44af85d53c 1063 Gene3D G3DSA:1.20.1640.10 518 1037 1.0E-292 T 13-10-2018 Astex_3856 c0180bf62c05201223624f44af85d53c 1063 Gene3D G3DSA:3.30.70.1430 568 669 1.0E-292 T 13-10-2018 Astex_3856 c0180bf62c05201223624f44af85d53c 1063 Gene3D G3DSA:3.30.2090.10 188 278 1.0E-292 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Astex_3856 c0180bf62c05201223624f44af85d53c 1063 SUPERFAMILY SSF82693 567 667 1.57E-7 T 13-10-2018 Astex_3856 c0180bf62c05201223624f44af85d53c 1063 SUPERFAMILY SSF82693 155 333 6.15E-20 T 13-10-2018 Astex_3856 c0180bf62c05201223624f44af85d53c 1063 Gene3D G3DSA:3.30.70.1440 670 880 1.0E-292 T 13-10-2018 Astex_3856 c0180bf62c05201223624f44af85d53c 1063 Gene3D G3DSA:3.30.70.1430 42 830 1.0E-292 T 13-10-2018 Astex_3856 c0180bf62c05201223624f44af85d53c 1063 SUPERFAMILY SSF82714 192 274 3.27E-17 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Astex_3856 c0180bf62c05201223624f44af85d53c 1063 Pfam PF00873 AcrB/AcrD/AcrF family 6 1041 0.0 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3856 c0180bf62c05201223624f44af85d53c 1063 SUPERFAMILY SSF82866 818 1044 1.07E-51 T 13-10-2018 Astex_3856 c0180bf62c05201223624f44af85d53c 1063 Gene3D G3DSA:3.30.70.1320 136 335 1.0E-292 T 13-10-2018 Astex_3856 c0180bf62c05201223624f44af85d53c 1063 SUPERFAMILY SSF82693 42 128 1.92E-23 T 13-10-2018 Astex_3856 c0180bf62c05201223624f44af85d53c 1063 Gene3D G3DSA:3.30.2090.10 724 822 1.0E-292 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Astex_3856 c0180bf62c05201223624f44af85d53c 1063 SUPERFAMILY SSF82714 725 819 1.57E-16 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Astex_3856 c0180bf62c05201223624f44af85d53c 1063 SUPERFAMILY SSF82866 299 506 2.09E-31 T 13-10-2018 Astex_1323 1dcd3c53193db25c1a5b0069fd83aebe 359 Pfam PF06379 L-rhamnose-proton symport protein (RhaT) 6 349 7.5E-73 T 13-10-2018 IPR004673 L-rhamnose-proton symport, RhaT GO:0008645|GO:0015153|GO:0016021 Astex_3297 8ce77043f780a529baa11fd80d37aecd 428 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 127 422 6.1E-56 T 13-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 Astex_3297 8ce77043f780a529baa11fd80d37aecd 428 TIGRFAM TIGR01266 fum_ac_acetase: fumarylacetoacetase 12 426 2.3E-155 T 13-10-2018 IPR005959 Fumarylacetoacetase GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 Astex_3297 8ce77043f780a529baa11fd80d37aecd 428 SUPERFAMILY SSF63433 11 121 5.23E-24 T 13-10-2018 IPR036462 Fumarylacetoacetase, N-terminal domain superfamily GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 Astex_3297 8ce77043f780a529baa11fd80d37aecd 428 Gene3D G3DSA:3.90.850.10 119 427 5.4E-114 T 13-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 Astex_3297 8ce77043f780a529baa11fd80d37aecd 428 Gene3D G3DSA:2.30.30.230 1 117 1.8E-25 T 13-10-2018 IPR036462 Fumarylacetoacetase, N-terminal domain superfamily GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 Astex_3297 8ce77043f780a529baa11fd80d37aecd 428 SUPERFAMILY SSF56529 123 425 1.83E-89 T 13-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 Astex_3297 8ce77043f780a529baa11fd80d37aecd 428 Pfam PF09298 Fumarylacetoacetase N-terminal 26 121 5.6E-16 T 13-10-2018 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 Astex_3006 d56eb68bdbea29ef6fb94d3ff935e854 163 SUPERFAMILY SSF51230 89 163 9.42E-24 T 13-10-2018 IPR011053 Single hybrid motif Astex_3006 d56eb68bdbea29ef6fb94d3ff935e854 163 Pfam PF00364 Biotin-requiring enzyme 90 162 7.2E-23 T 13-10-2018 IPR000089 Biotin/lipoyl attachment Astex_3006 d56eb68bdbea29ef6fb94d3ff935e854 163 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 119 136 - T 13-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Astex_3006 d56eb68bdbea29ef6fb94d3ff935e854 163 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 13 163 1.7E-41 T 13-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 Astex_3006 d56eb68bdbea29ef6fb94d3ff935e854 163 Gene3D G3DSA:2.40.50.100 85 163 3.9E-28 T 13-10-2018 Astex_3006 d56eb68bdbea29ef6fb94d3ff935e854 163 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 109 123 7.4E-14 T 13-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 Astex_3006 d56eb68bdbea29ef6fb94d3ff935e854 163 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 124 137 7.4E-14 T 13-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 Astex_3006 d56eb68bdbea29ef6fb94d3ff935e854 163 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 92 105 7.4E-14 T 13-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 Astex_2773 e0d4b940b9a4d1abe4e617f184cead4d 668 TIGRFAM TIGR01055 parE_Gneg: DNA topoisomerase IV, B subunit 28 660 9.6E-232 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 Astex_2773 e0d4b940b9a4d1abe4e617f184cead4d 668 SMART SM00387 54 199 6.8E-28 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_2773 e0d4b940b9a4d1abe4e617f184cead4d 668 PRINTS PR00418 DNA topoisomerase II family signature 556 568 2.1E-64 T 13-10-2018 Astex_2773 e0d4b940b9a4d1abe4e617f184cead4d 668 PRINTS PR00418 DNA topoisomerase II family signature 452 466 2.1E-64 T 13-10-2018 Astex_2773 e0d4b940b9a4d1abe4e617f184cead4d 668 PRINTS PR00418 DNA topoisomerase II family signature 518 534 2.1E-64 T 13-10-2018 Astex_2773 e0d4b940b9a4d1abe4e617f184cead4d 668 PRINTS PR00418 DNA topoisomerase II family signature 137 151 2.1E-64 T 13-10-2018 Astex_2773 e0d4b940b9a4d1abe4e617f184cead4d 668 PRINTS PR00418 DNA topoisomerase II family signature 93 106 2.1E-64 T 13-10-2018 Astex_2773 e0d4b940b9a4d1abe4e617f184cead4d 668 PRINTS PR00418 DNA topoisomerase II family signature 303 316 2.1E-64 T 13-10-2018 Astex_2773 e0d4b940b9a4d1abe4e617f184cead4d 668 PRINTS PR00418 DNA topoisomerase II family signature 536 553 2.1E-64 T 13-10-2018 Astex_2773 e0d4b940b9a4d1abe4e617f184cead4d 668 PRINTS PR00418 DNA topoisomerase II family signature 598 614 2.1E-64 T 13-10-2018 Astex_2773 e0d4b940b9a4d1abe4e617f184cead4d 668 PRINTS PR00418 DNA topoisomerase II family signature 58 73 2.1E-64 T 13-10-2018 Astex_2773 e0d4b940b9a4d1abe4e617f184cead4d 668 SUPERFAMILY SSF56719 427 659 1.23E-76 T 13-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 Astex_2773 e0d4b940b9a4d1abe4e617f184cead4d 668 Pfam PF01751 Toprim domain 451 551 2.8E-17 T 13-10-2018 IPR006171 TOPRIM domain Astex_2773 e0d4b940b9a4d1abe4e617f184cead4d 668 Gene3D G3DSA:3.40.50.670 431 668 8.3E-87 T 13-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Astex_2773 e0d4b940b9a4d1abe4e617f184cead4d 668 SUPERFAMILY SSF55874 29 236 2.75E-57 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_2773 e0d4b940b9a4d1abe4e617f184cead4d 668 PRINTS PR01098 Topoisomerase IV subunit B signature 620 634 5.7E-11 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 Astex_2773 e0d4b940b9a4d1abe4e617f184cead4d 668 PRINTS PR01098 Topoisomerase IV subunit B signature 53 66 5.7E-11 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 Astex_2773 e0d4b940b9a4d1abe4e617f184cead4d 668 PRINTS PR01098 Topoisomerase IV subunit B signature 542 558 5.7E-11 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 Astex_2773 e0d4b940b9a4d1abe4e617f184cead4d 668 PRINTS PR01098 Topoisomerase IV subunit B signature 398 423 5.7E-11 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 Astex_2773 e0d4b940b9a4d1abe4e617f184cead4d 668 PRINTS PR01098 Topoisomerase IV subunit B signature 272 295 5.7E-11 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 Astex_2773 e0d4b940b9a4d1abe4e617f184cead4d 668 PRINTS PR01098 Topoisomerase IV subunit B signature 486 507 5.7E-11 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 Astex_2773 e0d4b940b9a4d1abe4e617f184cead4d 668 PRINTS PR01098 Topoisomerase IV subunit B signature 374 397 5.7E-11 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 Astex_2773 e0d4b940b9a4d1abe4e617f184cead4d 668 Hamap MF_00938 DNA topoisomerase 4 subunit B [parE]. 26 664 42.687 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 Astex_2773 e0d4b940b9a4d1abe4e617f184cead4d 668 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 54 198 6.9E-20 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_2773 e0d4b940b9a4d1abe4e617f184cead4d 668 Gene3D G3DSA:3.30.230.10 251 427 5.9E-46 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Astex_2773 e0d4b940b9a4d1abe4e617f184cead4d 668 ProSitePatterns PS00177 DNA topoisomerase II signature. 454 462 - T 13-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Astex_2773 e0d4b940b9a4d1abe4e617f184cead4d 668 Pfam PF00204 DNA gyrase B 251 423 1.4E-41 T 13-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Astex_2773 e0d4b940b9a4d1abe4e617f184cead4d 668 Gene3D G3DSA:3.30.565.10 26 241 7.5E-76 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_2773 e0d4b940b9a4d1abe4e617f184cead4d 668 SMART SM00433 58 660 1.5E-285 T 13-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Astex_2773 e0d4b940b9a4d1abe4e617f184cead4d 668 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 594 656 3.0E-24 T 13-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Astex_2773 e0d4b940b9a4d1abe4e617f184cead4d 668 SUPERFAMILY SSF54211 251 424 1.82E-40 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Astex_1824 df3b94ad56621b650580a619f17f1177 330 TIGRFAM TIGR01249 pro_imino_pep_1: prolyl aminopeptidase 18 324 4.6E-127 T 13-10-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 Astex_1824 df3b94ad56621b650580a619f17f1177 330 Pfam PF00561 alpha/beta hydrolase fold 45 309 7.2E-33 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Astex_1824 df3b94ad56621b650580a619f17f1177 330 SUPERFAMILY SSF53474 8 309 6.06E-60 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1824 df3b94ad56621b650580a619f17f1177 330 Gene3D G3DSA:3.40.50.1820 11 325 7.3E-103 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1824 df3b94ad56621b650580a619f17f1177 330 PRINTS PR00111 Alpha/beta hydrolase fold signature 119 132 1.7E-5 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Astex_1824 df3b94ad56621b650580a619f17f1177 330 PRINTS PR00111 Alpha/beta hydrolase fold signature 69 84 1.7E-5 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Astex_1824 df3b94ad56621b650580a619f17f1177 330 PRINTS PR00111 Alpha/beta hydrolase fold signature 133 146 1.7E-5 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Astex_1824 df3b94ad56621b650580a619f17f1177 330 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 72 83 1.4E-13 T 13-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 Astex_1824 df3b94ad56621b650580a619f17f1177 330 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 46 54 1.4E-13 T 13-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 Astex_1824 df3b94ad56621b650580a619f17f1177 330 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 119 133 1.4E-13 T 13-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 Astex_1824 df3b94ad56621b650580a619f17f1177 330 PIRSF PIRSF006431 9 329 1.2E-134 T 13-10-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 Astex_2167 75d9c51655a5fffa3042a8aaa737ef9a 282 Pfam PF08220 DeoR-like helix-turn-helix domain 6 60 1.4E-15 T 13-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 Astex_2167 75d9c51655a5fffa3042a8aaa737ef9a 282 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 13-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 Astex_2167 75d9c51655a5fffa3042a8aaa737ef9a 282 SMART SM00420 6 58 1.3E-16 T 13-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 Astex_2167 75d9c51655a5fffa3042a8aaa737ef9a 282 SUPERFAMILY SSF100950 94 251 1.26E-24 T 13-10-2018 IPR037171 NagB/RpiA transferase-like Astex_2167 75d9c51655a5fffa3042a8aaa737ef9a 282 SUPERFAMILY SSF46785 3 60 5.88E-14 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_2167 75d9c51655a5fffa3042a8aaa737ef9a 282 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 2.6E-8 T 13-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 Astex_2167 75d9c51655a5fffa3042a8aaa737ef9a 282 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 2.6E-8 T 13-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 Astex_2167 75d9c51655a5fffa3042a8aaa737ef9a 282 SMART SM01134 91 250 2.4E-47 T 13-10-2018 Astex_2167 75d9c51655a5fffa3042a8aaa737ef9a 282 Gene3D G3DSA:1.10.10.10 1 55 7.6E-6 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_2167 75d9c51655a5fffa3042a8aaa737ef9a 282 Pfam PF00455 DeoR C terminal sensor domain 94 249 2.9E-40 T 13-10-2018 IPR014036 DeoR C-terminal sensor domain Astex_3151 a53af347f40ebc4292795fd8017070d4 707 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 160 282 5.0E-13 T 13-10-2018 IPR000014 PAS domain Astex_3151 a53af347f40ebc4292795fd8017070d4 707 Gene3D G3DSA:3.30.450.20 152 284 1.7E-25 T 13-10-2018 Astex_3151 a53af347f40ebc4292795fd8017070d4 707 Pfam PF08448 PAS fold 169 277 2.7E-19 T 13-10-2018 IPR013656 PAS fold-4 Astex_3151 a53af347f40ebc4292795fd8017070d4 707 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 285 443 5.7E-40 T 13-10-2018 IPR000160 GGDEF domain Astex_3151 a53af347f40ebc4292795fd8017070d4 707 SUPERFAMILY SSF54631 14 146 1.72E-6 T 13-10-2018 Astex_3151 a53af347f40ebc4292795fd8017070d4 707 Gene3D G3DSA:3.30.70.270 285 460 7.3E-58 T 13-10-2018 Astex_3151 a53af347f40ebc4292795fd8017070d4 707 Gene3D G3DSA:3.10.580.10 7 135 6.5E-6 T 13-10-2018 Astex_3151 a53af347f40ebc4292795fd8017070d4 707 SMART SM00267 276 447 9.6E-66 T 13-10-2018 IPR000160 GGDEF domain Astex_3151 a53af347f40ebc4292795fd8017070d4 707 SMART SM00091 162 228 5.7E-9 T 13-10-2018 IPR000014 PAS domain Astex_3151 a53af347f40ebc4292795fd8017070d4 707 SUPERFAMILY SSF141868 462 700 1.83E-93 T 13-10-2018 IPR035919 EAL domain superfamily Astex_3151 a53af347f40ebc4292795fd8017070d4 707 Pfam PF00990 Diguanylate cyclase, GGDEF domain 287 442 7.6E-46 T 13-10-2018 IPR000160 GGDEF domain Astex_3151 a53af347f40ebc4292795fd8017070d4 707 SMART SM00052 457 699 9.1E-125 T 13-10-2018 IPR001633 EAL domain Astex_3151 a53af347f40ebc4292795fd8017070d4 707 SUPERFAMILY SSF55073 292 448 1.02E-49 T 13-10-2018 IPR029787 Nucleotide cyclase Astex_3151 a53af347f40ebc4292795fd8017070d4 707 SUPERFAMILY SSF55785 147 274 1.92E-17 T 13-10-2018 IPR035965 PAS domain superfamily Astex_3151 a53af347f40ebc4292795fd8017070d4 707 Pfam PF00563 EAL domain 464 694 2.0E-77 T 13-10-2018 IPR001633 EAL domain Astex_3151 a53af347f40ebc4292795fd8017070d4 707 Gene3D G3DSA:3.20.20.450 461 705 1.7E-103 T 13-10-2018 IPR035919 EAL domain superfamily Astex_2786 65b8f404257bf7e9080ebde57ab506f7 649 SUPERFAMILY SSF53474 390 645 6.76E-66 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_2786 65b8f404257bf7e9080ebde57ab506f7 649 Pfam PF00326 Prolyl oligopeptidase family 435 645 8.1E-41 T 13-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 Astex_2786 65b8f404257bf7e9080ebde57ab506f7 649 SUPERFAMILY SSF82171 47 374 6.67E-11 T 13-10-2018 Astex_2786 65b8f404257bf7e9080ebde57ab506f7 649 Gene3D G3DSA:3.40.50.1820 381 647 2.6E-72 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_3121 a79736c7b8b0c62cb48c01e829ac0e25 294 SUPERFAMILY SSF55681 7 291 3.73E-124 T 13-10-2018 Astex_3121 a79736c7b8b0c62cb48c01e829ac0e25 294 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 7 293 3.1E-138 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 Astex_3121 a79736c7b8b0c62cb48c01e829ac0e25 294 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 6 293 58.563 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 Astex_3121 a79736c7b8b0c62cb48c01e829ac0e25 294 Gene3D G3DSA:3.30.930.10 1 210 4.5E-106 T 13-10-2018 Astex_3121 a79736c7b8b0c62cb48c01e829ac0e25 294 Gene3D G3DSA:1.20.58.180 211 294 4.8E-28 T 13-10-2018 Astex_3121 a79736c7b8b0c62cb48c01e829ac0e25 294 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 161 176 1.8E-63 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 Astex_3121 a79736c7b8b0c62cb48c01e829ac0e25 294 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 60 75 1.8E-63 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 Astex_3121 a79736c7b8b0c62cb48c01e829ac0e25 294 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 253 269 1.8E-63 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 Astex_3121 a79736c7b8b0c62cb48c01e829ac0e25 294 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 112 136 1.8E-63 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 Astex_3121 a79736c7b8b0c62cb48c01e829ac0e25 294 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 81 101 1.8E-63 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 Astex_3121 a79736c7b8b0c62cb48c01e829ac0e25 294 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 138 158 1.8E-63 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 Astex_3121 a79736c7b8b0c62cb48c01e829ac0e25 294 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 8 291 1.4E-144 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 Astex_1862 a90c2e8b9441324509c24857bf758309 329 SUPERFAMILY SSF52440 1 122 1.06E-14 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily Astex_1862 a90c2e8b9441324509c24857bf758309 329 Gene3D G3DSA:3.30.1490.20 139 196 1.3E-62 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 Astex_1862 a90c2e8b9441324509c24857bf758309 329 Gene3D G3DSA:3.40.50.20 83 317 1.3E-62 T 13-10-2018 Astex_1862 a90c2e8b9441324509c24857bf758309 329 Pfam PF07478 D-ala D-ala ligase C-terminus 157 316 5.0E-38 T 13-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Astex_1862 a90c2e8b9441324509c24857bf758309 329 Gene3D G3DSA:3.30.470.20 112 314 1.3E-62 T 13-10-2018 Astex_1862 a90c2e8b9441324509c24857bf758309 329 Pfam PF01820 D-ala D-ala ligase N-terminus 3 113 1.2E-10 T 13-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Astex_1862 a90c2e8b9441324509c24857bf758309 329 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 267 294 - T 13-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Astex_1862 a90c2e8b9441324509c24857bf758309 329 SUPERFAMILY SSF56059 123 317 6.06E-41 T 13-10-2018 Astex_0448 ca5cb33fec0f14738670e84139b7ae76 862 Pfam PF11791 Aconitate B N-terminal domain 4 156 1.7E-63 T 13-10-2018 IPR015933 Aconitase B, HEAT-like domain GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 Astex_0448 ca5cb33fec0f14738670e84139b7ae76 862 ProSitePatterns PS00450 Aconitase family signature 1. 703 720 - T 13-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 Astex_0448 ca5cb33fec0f14738670e84139b7ae76 862 Pfam PF06434 Aconitate hydratase 2 N-terminus 168 380 3.2E-94 T 13-10-2018 IPR015929 Aconitase B, swivel GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 Astex_0448 ca5cb33fec0f14738670e84139b7ae76 862 SUPERFAMILY SSF53732 377 854 4.84E-140 T 13-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 Astex_0448 ca5cb33fec0f14738670e84139b7ae76 862 Gene3D G3DSA:3.40.1060.10 383 682 3.3E-147 T 13-10-2018 IPR015932 Aconitase, domain 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-1268020|Reactome: R-HSA-71403 Astex_0448 ca5cb33fec0f14738670e84139b7ae76 862 SUPERFAMILY SSF52016 162 370 1.22E-64 T 13-10-2018 Astex_0448 ca5cb33fec0f14738670e84139b7ae76 862 Pfam PF00330 Aconitase family (aconitate hydratase) 471 814 9.4E-38 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Astex_0448 ca5cb33fec0f14738670e84139b7ae76 862 Gene3D G3DSA:3.30.499.10 403 530 3.3E-147 T 13-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 Astex_0448 ca5cb33fec0f14738670e84139b7ae76 862 Gene3D G3DSA:3.20.19.10 162 359 3.7E-72 T 13-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 Astex_0448 ca5cb33fec0f14738670e84139b7ae76 862 SUPERFAMILY SSF74778 1 160 1.15E-66 T 13-10-2018 IPR036288 Aconitase B, HEAT-like domain superfamily GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 Astex_0448 ca5cb33fec0f14738670e84139b7ae76 862 PIRSF PIRSF036687 1 859 0.0 T 13-10-2018 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 Astex_0448 ca5cb33fec0f14738670e84139b7ae76 862 TIGRFAM TIGR00117 acnB: aconitate hydratase 2 1 853 0.0 T 13-10-2018 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 Astex_0448 ca5cb33fec0f14738670e84139b7ae76 862 Gene3D G3DSA:3.30.499.10 684 862 9.7E-61 T 13-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 Astex_0448 ca5cb33fec0f14738670e84139b7ae76 862 Gene3D G3DSA:1.25.40.310 1 161 6.9E-66 T 13-10-2018 IPR036288 Aconitase B, HEAT-like domain superfamily GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 Astex_0263 be513296f9586a17599adf802099e171 481 SUPERFAMILY SSF50615 9 84 3.66E-24 T 13-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Astex_0263 be513296f9586a17599adf802099e171 481 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 11 477 5.8E-250 T 13-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 Astex_0263 be513296f9586a17599adf802099e171 481 Hamap MF_01347 ATP synthase subunit beta [atpB]. 9 477 56.929 T 13-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 Astex_0263 be513296f9586a17599adf802099e171 481 PIRSF PIRSF039072 1 481 8.6E-284 T 13-10-2018 Astex_0263 be513296f9586a17599adf802099e171 481 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 139 359 2.2E-64 T 13-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Astex_0263 be513296f9586a17599adf802099e171 481 Gene3D G3DSA:1.10.1140.10 362 481 2.1E-57 T 13-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Astex_0263 be513296f9586a17599adf802099e171 481 SMART SM00382 151 336 3.1E-6 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_0263 be513296f9586a17599adf802099e171 481 Gene3D G3DSA:3.40.50.300 85 361 1.1E-117 T 13-10-2018 Astex_0263 be513296f9586a17599adf802099e171 481 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 350 359 - T 13-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Astex_0263 be513296f9586a17599adf802099e171 481 Gene3D G3DSA:2.40.10.170 1 84 9.3E-33 T 13-10-2018 Astex_0263 be513296f9586a17599adf802099e171 481 SUPERFAMILY SSF47917 362 477 2.59E-52 T 13-10-2018 Astex_0263 be513296f9586a17599adf802099e171 481 SUPERFAMILY SSF52540 86 364 1.1E-88 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0263 be513296f9586a17599adf802099e171 481 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 14 82 3.6E-21 T 13-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Astex_3475 111612488ae03ef073937bf2348d1de3 801 SUPERFAMILY SSF56935 137 801 8.63E-71 T 13-10-2018 Astex_3475 111612488ae03ef073937bf2348d1de3 801 Pfam PF00593 TonB dependent receptor 376 798 1.8E-25 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_3475 111612488ae03ef073937bf2348d1de3 801 Gene3D G3DSA:2.40.170.20 144 801 2.2E-92 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_3475 111612488ae03ef073937bf2348d1de3 801 Gene3D G3DSA:3.55.50.30 29 123 1.4E-8 T 13-10-2018 Astex_3475 111612488ae03ef073937bf2348d1de3 801 Pfam PF07715 TonB-dependent Receptor Plug Domain 143 249 3.2E-7 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_2135 ae1fee37893207d83dc3a1472910fed8 398 Pfam PF13378 Enolase C-terminal domain-like 194 389 1.7E-42 T 13-10-2018 IPR029065 Enolase C-terminal domain-like Astex_2135 ae1fee37893207d83dc3a1472910fed8 398 Hamap MF_01288 L-rhamnonate dehydratase [rhmD]. 1 398 76.04 T 13-10-2018 IPR023444 L-rhamnonate dehydratase GO:0050032 KEGG: 00051+4.2.1.90|MetaCyc: PWY-6713|MetaCyc: PWY-6714 Astex_2135 ae1fee37893207d83dc3a1472910fed8 398 SUPERFAMILY SSF51604 141 390 1.44E-58 T 13-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily Astex_2135 ae1fee37893207d83dc3a1472910fed8 398 Gene3D G3DSA:3.20.20.120 153 390 7.9E-204 T 13-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily Astex_2135 ae1fee37893207d83dc3a1472910fed8 398 SUPERFAMILY SSF54826 44 158 3.98E-29 T 13-10-2018 Astex_2135 ae1fee37893207d83dc3a1472910fed8 398 SMART SM00922 159 265 2.3E-7 T 13-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal Astex_2135 ae1fee37893207d83dc3a1472910fed8 398 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 63 153 4.3E-9 T 13-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain Astex_2135 ae1fee37893207d83dc3a1472910fed8 398 Gene3D G3DSA:3.30.390.10 4 152 7.9E-204 T 13-10-2018 IPR029017 Enolase-like, N-terminal Astex_3593 9c6cca4d09dd1961be27c0640df44a73 456 SUPERFAMILY SSF82171 123 453 1.44E-20 T 13-10-2018 Astex_3593 9c6cca4d09dd1961be27c0640df44a73 456 Pfam PF14583 Oligogalacturonate lyase 228 449 4.2E-12 T 13-10-2018 IPR027946 Oligogalacturonate lyase domain GO:0045490|GO:0047487 KEGG: 00040+4.2.2.6 Astex_3593 9c6cca4d09dd1961be27c0640df44a73 456 Gene3D G3DSA:2.130.10.10 43 453 2.2E-84 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 Astex_3136 15abdc9e8c5931ea383ce586e0cdc50b 938 Pfam PF08264 Anticodon-binding domain of tRNA 667 810 2.7E-40 T 13-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 Astex_3136 15abdc9e8c5931ea383ce586e0cdc50b 938 Gene3D G3DSA:1.10.287.380 863 935 2.5E-16 T 13-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 Astex_3136 15abdc9e8c5931ea383ce586e0cdc50b 938 SUPERFAMILY SSF46589 870 934 5.75E-13 T 13-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 Astex_3136 15abdc9e8c5931ea383ce586e0cdc50b 938 SUPERFAMILY SSF50677 192 361 3.66E-57 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Astex_3136 15abdc9e8c5931ea383ce586e0cdc50b 938 PRINTS PR00986 Valyl-tRNA synthetase signature 536 554 5.7E-38 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 Astex_3136 15abdc9e8c5931ea383ce586e0cdc50b 938 PRINTS PR00986 Valyl-tRNA synthetase signature 249 266 5.7E-38 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 Astex_3136 15abdc9e8c5931ea383ce586e0cdc50b 938 PRINTS PR00986 Valyl-tRNA synthetase signature 36 47 5.7E-38 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 Astex_3136 15abdc9e8c5931ea383ce586e0cdc50b 938 PRINTS PR00986 Valyl-tRNA synthetase signature 505 526 5.7E-38 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 Astex_3136 15abdc9e8c5931ea383ce586e0cdc50b 938 PRINTS PR00986 Valyl-tRNA synthetase signature 365 378 5.7E-38 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 Astex_3136 15abdc9e8c5931ea383ce586e0cdc50b 938 SUPERFAMILY SSF52374 3 634 4.41E-136 T 13-10-2018 Astex_3136 15abdc9e8c5931ea383ce586e0cdc50b 938 TIGRFAM TIGR00422 valS: valine--tRNA ligase 3 917 0.0 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 Astex_3136 15abdc9e8c5931ea383ce586e0cdc50b 938 Hamap MF_02004 Valine--tRNA ligase [valS]. 2 935 15.66 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 Astex_3136 15abdc9e8c5931ea383ce586e0cdc50b 938 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 15 623 1.0E-209 T 13-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Astex_3136 15abdc9e8c5931ea383ce586e0cdc50b 938 Gene3D G3DSA:3.40.50.620 22 585 1.5E-290 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Astex_3136 15abdc9e8c5931ea383ce586e0cdc50b 938 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 870 935 7.1E-16 T 13-10-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 Astex_3136 15abdc9e8c5931ea383ce586e0cdc50b 938 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 54 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Astex_3136 15abdc9e8c5931ea383ce586e0cdc50b 938 Gene3D G3DSA:1.10.730.10 2 799 1.5E-290 T 13-10-2018 Astex_3136 15abdc9e8c5931ea383ce586e0cdc50b 938 SUPERFAMILY SSF47323 636 883 3.36E-54 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Astex_3136 15abdc9e8c5931ea383ce586e0cdc50b 938 Gene3D G3DSA:3.90.740.10 176 361 1.5E-290 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Astex_2341 17c391fc3affc008cc4e93b2d4227ff2 535 Pfam PF04616 Glycosyl hydrolases family 43 55 327 1.7E-84 T 13-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 Astex_2341 17c391fc3affc008cc4e93b2d4227ff2 535 Gene3D G3DSA:2.115.10.20 54 337 1.7E-69 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Astex_2341 17c391fc3affc008cc4e93b2d4227ff2 535 SUPERFAMILY SSF49899 352 523 3.17E-21 T 13-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily Astex_2341 17c391fc3affc008cc4e93b2d4227ff2 535 SUPERFAMILY SSF75005 55 332 2.36E-72 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Astex_2341 17c391fc3affc008cc4e93b2d4227ff2 535 Gene3D G3DSA:2.60.120.200 353 533 8.3E-19 T 13-10-2018 Astex_3467 1ed7f42c3c9dd345bf663c36dda3e4d1 988 SUPERFAMILY SSF50677 215 460 6.7E-39 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Astex_3467 1ed7f42c3c9dd345bf663c36dda3e4d1 988 Pfam PF08264 Anticodon-binding domain of tRNA 742 891 1.6E-21 T 13-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 Astex_3467 1ed7f42c3c9dd345bf663c36dda3e4d1 988 SUPERFAMILY SSF47323 710 982 1.96E-51 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Astex_3467 1ed7f42c3c9dd345bf663c36dda3e4d1 988 SUPERFAMILY SSF52374 9 705 4.69E-132 T 13-10-2018 Astex_3467 1ed7f42c3c9dd345bf663c36dda3e4d1 988 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 65 76 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Astex_3467 1ed7f42c3c9dd345bf663c36dda3e4d1 988 Gene3D G3DSA:1.10.730.20 698 982 1.4E-71 T 13-10-2018 Astex_3467 1ed7f42c3c9dd345bf663c36dda3e4d1 988 Gene3D G3DSA:3.90.740.10 205 465 3.0E-219 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Astex_3467 1ed7f42c3c9dd345bf663c36dda3e4d1 988 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 33 698 2.9E-176 T 13-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Astex_3467 1ed7f42c3c9dd345bf663c36dda3e4d1 988 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 262 285 7.8E-24 T 13-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 Astex_3467 1ed7f42c3c9dd345bf663c36dda3e4d1 988 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 585 598 7.8E-24 T 13-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 Astex_3467 1ed7f42c3c9dd345bf663c36dda3e4d1 988 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 619 628 7.8E-24 T 13-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 Astex_3467 1ed7f42c3c9dd345bf663c36dda3e4d1 988 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 58 69 7.8E-24 T 13-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 Astex_3467 1ed7f42c3c9dd345bf663c36dda3e4d1 988 Gene3D G3DSA:3.40.50.620 30 687 3.0E-219 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Astex_3467 1ed7f42c3c9dd345bf663c36dda3e4d1 988 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 7 981 19.624 T 13-10-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 Astex_3467 1ed7f42c3c9dd345bf663c36dda3e4d1 988 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 20 893 1.8E-242 T 13-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 Astex_2734 5623ae00f609feb44056882a10350c0c 322 Gene3D G3DSA:3.40.1280.10 150 320 1.5E-49 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Astex_2734 5623ae00f609feb44056882a10350c0c 322 SMART SM00967 75 150 3.6E-9 T 13-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 Astex_2734 5623ae00f609feb44056882a10350c0c 322 Pfam PF00588 SpoU rRNA Methylase family 166 315 1.5E-37 T 13-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 Astex_2734 5623ae00f609feb44056882a10350c0c 322 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 75 146 2.2E-6 T 13-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 Astex_2734 5623ae00f609feb44056882a10350c0c 322 SUPERFAMILY SSF55315 71 143 4.94E-6 T 13-10-2018 IPR029064 50S ribosomal protein L30e-like Astex_2734 5623ae00f609feb44056882a10350c0c 322 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 76 318 1.1E-57 T 13-10-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 Astex_2734 5623ae00f609feb44056882a10350c0c 322 SUPERFAMILY SSF75217 162 318 4.5E-42 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases Astex_0948 c6577e3c44335acc59f9d9ec06670981 278 SUPERFAMILY SSF50104 126 272 1.02E-60 T 13-10-2018 IPR008991 Translation protein SH3-like domain superfamily Astex_0948 c6577e3c44335acc59f9d9ec06670981 278 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 250 2.5E-56 T 13-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 Astex_0948 c6577e3c44335acc59f9d9ec06670981 278 PIRSF PIRSF002158 4 275 3.8E-94 T 13-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_0948 c6577e3c44335acc59f9d9ec06670981 278 SUPERFAMILY SSF50249 2 125 1.47E-43 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Astex_0948 c6577e3c44335acc59f9d9ec06670981 278 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 273 4.1E-124 T 13-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Astex_0948 c6577e3c44335acc59f9d9ec06670981 278 SMART SM01382 124 252 1.8E-89 T 13-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 Astex_0948 c6577e3c44335acc59f9d9ec06670981 278 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 45.098 T 13-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Astex_0948 c6577e3c44335acc59f9d9ec06670981 278 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 117 6.0E-29 T 13-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_0948 c6577e3c44335acc59f9d9ec06670981 278 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 13-10-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0948 c6577e3c44335acc59f9d9ec06670981 278 SMART SM01383 42 118 2.0E-40 T 13-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_0948 c6577e3c44335acc59f9d9ec06670981 278 Gene3D G3DSA:2.40.50.140 1 114 4.3E-42 T 13-10-2018 Astex_0948 c6577e3c44335acc59f9d9ec06670981 278 Gene3D G3DSA:2.30.30.30 118 196 2.3E-31 T 13-10-2018 IPR014722 Ribosomal protein L2, domain 2 Astex_0948 c6577e3c44335acc59f9d9ec06670981 278 Gene3D G3DSA:4.10.950.10 197 274 6.8E-35 T 13-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_3568 26120976df125c9d2b0122652da093f4 562 Gene3D G3DSA:1.10.287.950 274 561 4.9E-49 T 13-10-2018 Astex_3568 26120976df125c9d2b0122652da093f4 562 Pfam PF00672 HAMP domain 214 260 1.6E-7 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Astex_3568 26120976df125c9d2b0122652da093f4 562 Gene3D G3DSA:1.20.1480.50 169 271 7.4E-12 T 13-10-2018 Astex_3568 26120976df125c9d2b0122652da093f4 562 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 362 525 1.2E-25 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_3568 26120976df125c9d2b0122652da093f4 562 SMART SM00283 302 556 1.9E-37 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_3568 26120976df125c9d2b0122652da093f4 562 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 400 427 9.0E-18 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_3568 26120976df125c9d2b0122652da093f4 562 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 429 458 9.0E-18 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_3568 26120976df125c9d2b0122652da093f4 562 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 6 31 9.0E-18 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_3568 26120976df125c9d2b0122652da093f4 562 SMART SM00304 212 265 1.5E-7 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Astex_3568 26120976df125c9d2b0122652da093f4 562 SUPERFAMILY SSF58104 242 555 1.07E-57 T 13-10-2018 Astex_1580 93eff2a145b4d92fb15140b06c0b5d59 233 SMART SM00448 13 123 1.0E-40 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1580 93eff2a145b4d92fb15140b06c0b5d59 233 SMART SM00862 158 230 1.5E-18 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Astex_1580 93eff2a145b4d92fb15140b06c0b5d59 233 Gene3D G3DSA:1.10.10.10 132 233 7.9E-27 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1580 93eff2a145b4d92fb15140b06c0b5d59 233 Pfam PF00072 Response regulator receiver domain 16 123 5.0E-28 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1580 93eff2a145b4d92fb15140b06c0b5d59 233 Gene3D G3DSA:3.40.50.2300 12 131 3.9E-36 T 13-10-2018 Astex_1580 93eff2a145b4d92fb15140b06c0b5d59 233 SUPERFAMILY SSF52172 14 138 2.42E-39 T 13-10-2018 IPR011006 CheY-like superfamily Astex_1580 93eff2a145b4d92fb15140b06c0b5d59 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 160 230 3.0E-18 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Astex_1580 93eff2a145b4d92fb15140b06c0b5d59 233 SUPERFAMILY SSF46894 138 231 1.3E-21 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Astex_2772 5910de26152db97877a8904b09b4ee15 501 Gene3D G3DSA:3.40.50.300 217 407 3.4E-51 T 13-10-2018 Astex_2772 5910de26152db97877a8904b09b4ee15 501 Gene3D G3DSA:3.40.50.300 1 216 2.8E-78 T 13-10-2018 Astex_2772 5910de26152db97877a8904b09b4ee15 501 SMART SM00487 21 221 1.2E-67 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Astex_2772 5910de26152db97877a8904b09b4ee15 501 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 152 160 - T 13-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site Astex_2772 5910de26152db97877a8904b09b4ee15 501 SMART SM00490 264 345 6.7E-33 T 13-10-2018 IPR001650 Helicase, C-terminal Astex_2772 5910de26152db97877a8904b09b4ee15 501 Pfam PF00271 Helicase conserved C-terminal domain 246 345 3.8E-28 T 13-10-2018 IPR001650 Helicase, C-terminal Astex_2772 5910de26152db97877a8904b09b4ee15 501 SUPERFAMILY SSF52540 74 361 1.1E-76 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2772 5910de26152db97877a8904b09b4ee15 501 Pfam PF00270 DEAD/DEAH box helicase 26 194 1.2E-51 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Astex_3402 291d808f5fb691a147eac850229f92b6 740 Gene3D G3DSA:3.40.50.1700 361 624 7.7E-74 T 13-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 Astex_3402 291d808f5fb691a147eac850229f92b6 740 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 96 342 8.6E-45 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_3402 291d808f5fb691a147eac850229f92b6 740 Gene3D G3DSA:3.20.20.300 26 349 2.9E-98 T 13-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 Astex_3402 291d808f5fb691a147eac850229f92b6 740 SUPERFAMILY SSF51445 37 371 3.16E-86 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_3402 291d808f5fb691a147eac850229f92b6 740 SMART SM01217 655 722 2.5E-17 T 13-10-2018 IPR026891 Fibronectin type III-like domain Astex_3402 291d808f5fb691a147eac850229f92b6 740 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 375 623 1.2E-58 T 13-10-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 Astex_3402 291d808f5fb691a147eac850229f92b6 740 Gene3D G3DSA:2.60.40.10 626 739 7.8E-26 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_3402 291d808f5fb691a147eac850229f92b6 740 PRINTS PR00133 Glycosyl hydrolase family 3 signature 96 112 4.5E-30 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_3402 291d808f5fb691a147eac850229f92b6 740 PRINTS PR00133 Glycosyl hydrolase family 3 signature 203 219 4.5E-30 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_3402 291d808f5fb691a147eac850229f92b6 740 PRINTS PR00133 Glycosyl hydrolase family 3 signature 172 188 4.5E-30 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_3402 291d808f5fb691a147eac850229f92b6 740 PRINTS PR00133 Glycosyl hydrolase family 3 signature 273 291 4.5E-30 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_3402 291d808f5fb691a147eac850229f92b6 740 PRINTS PR00133 Glycosyl hydrolase family 3 signature 126 145 4.5E-30 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_3402 291d808f5fb691a147eac850229f92b6 740 SUPERFAMILY SSF52279 375 626 5.49E-52 T 13-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 Astex_3402 291d808f5fb691a147eac850229f92b6 740 Pfam PF14310 Fibronectin type III-like domain 657 720 4.0E-15 T 13-10-2018 IPR026891 Fibronectin type III-like domain Astex_0657 a97b3e813b5ca76ce9ac641429018416 688 SUPERFAMILY SSF81660 322 457 3.6E-30 T 13-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 Astex_0657 a97b3e813b5ca76ce9ac641429018416 688 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 447 458 1.4E-23 T 13-10-2018 Astex_0657 a97b3e813b5ca76ce9ac641429018416 688 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 522 541 1.4E-23 T 13-10-2018 Astex_0657 a97b3e813b5ca76ce9ac641429018416 688 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 545 557 1.4E-23 T 13-10-2018 Astex_0657 a97b3e813b5ca76ce9ac641429018416 688 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 311 325 1.4E-23 T 13-10-2018 Astex_0657 a97b3e813b5ca76ce9ac641429018416 688 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 469 479 1.4E-23 T 13-10-2018 Astex_0657 a97b3e813b5ca76ce9ac641429018416 688 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 154 168 1.4E-23 T 13-10-2018 Astex_0657 a97b3e813b5ca76ce9ac641429018416 688 Gene3D G3DSA:3.40.1110.10 323 453 6.3E-47 T 13-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 Astex_0657 a97b3e813b5ca76ce9ac641429018416 688 Pfam PF00702 haloacid dehalogenase-like hydrolase 307 536 1.3E-31 T 13-10-2018 Astex_0657 a97b3e813b5ca76ce9ac641429018416 688 SUPERFAMILY SSF56784 309 572 5.39E-37 T 13-10-2018 IPR036412 HAD-like superfamily Astex_0657 a97b3e813b5ca76ce9ac641429018416 688 Gene3D G3DSA:2.70.150.20 105 212 6.3E-28 T 13-10-2018 Astex_0657 a97b3e813b5ca76ce9ac641429018416 688 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 313 319 - T 13-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 Astex_0657 a97b3e813b5ca76ce9ac641429018416 688 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 12 680 0.0 T 13-10-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 Astex_0657 a97b3e813b5ca76ce9ac641429018416 688 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 6 686 39.867 T 13-10-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 Astex_0657 a97b3e813b5ca76ce9ac641429018416 688 SUPERFAMILY SSF81653 116 207 6.67E-23 T 13-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 Astex_0657 a97b3e813b5ca76ce9ac641429018416 688 Pfam PF00122 E1-E2 ATPase 109 290 2.1E-35 T 13-10-2018 Astex_0657 a97b3e813b5ca76ce9ac641429018416 688 SUPERFAMILY SSF81665 28 305 2.88E-9 T 13-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 Astex_0657 a97b3e813b5ca76ce9ac641429018416 688 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 75 346 1.9E-31 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Astex_0657 a97b3e813b5ca76ce9ac641429018416 688 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 374 607 3.1E-45 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Astex_0946 a6b1ae66e8e5dbbd821e1ce8fcd5923c 210 Pfam PF00573 Ribosomal protein L4/L1 family 16 204 1.9E-59 T 13-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 Astex_0946 a6b1ae66e8e5dbbd821e1ce8fcd5923c 210 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 16 203 2.3E-65 T 13-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0946 a6b1ae66e8e5dbbd821e1ce8fcd5923c 210 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 207 30.419 T 13-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0946 a6b1ae66e8e5dbbd821e1ce8fcd5923c 210 Gene3D G3DSA:3.40.1370.10 2 210 1.4E-66 T 13-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 Astex_0946 a6b1ae66e8e5dbbd821e1ce8fcd5923c 210 SUPERFAMILY SSF52166 1 206 6.93E-68 T 13-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 Astex_3581 9edccd2aa470d40785dca61610f2350e 513 Gene3D G3DSA:3.40.50.300 244 501 6.7E-47 T 13-10-2018 Astex_3581 9edccd2aa470d40785dca61610f2350e 513 SMART SM00382 285 480 3.2E-6 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_3581 9edccd2aa470d40785dca61610f2350e 513 SMART SM00382 28 247 1.8E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_3581 9edccd2aa470d40785dca61610f2350e 513 Pfam PF00005 ABC transporter 276 431 1.9E-23 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_3581 9edccd2aa470d40785dca61610f2350e 513 SUPERFAMILY SSF52540 3 227 2.98E-53 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_3581 9edccd2aa470d40785dca61610f2350e 513 SUPERFAMILY SSF52540 255 484 2.62E-46 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_3581 9edccd2aa470d40785dca61610f2350e 513 Gene3D G3DSA:3.40.50.300 1 243 9.1E-53 T 13-10-2018 Astex_3581 9edccd2aa470d40785dca61610f2350e 513 ProSitePatterns PS00211 ABC transporters family signature. 404 418 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Astex_3581 9edccd2aa470d40785dca61610f2350e 513 Pfam PF00005 ABC transporter 21 169 1.8E-27 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_2673 55ee910a30faa7a04409af30aa8540dc 352 Gene3D G3DSA:1.10.1200.160 297 327 9.5E-37 T 13-10-2018 Astex_2673 55ee910a30faa7a04409af30aa8540dc 352 Gene3D G3DSA:2.40.128.260 174 343 9.5E-37 T 13-10-2018 Astex_2673 55ee910a30faa7a04409af30aa8540dc 352 Pfam PF03743 Bacterial conjugation TrbI-like protein 172 344 6.2E-42 T 13-10-2018 IPR005498 Type IV secretion system, VirB10 / TraB / TrbI Astex_0610 1167bbbd1d3d122109fdae85847c7f92 170 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 8 89 2.4E-7 T 13-10-2018 IPR023485 Phosphotyrosine protein phosphatase I Astex_0610 1167bbbd1d3d122109fdae85847c7f92 170 SMART SM00226 6 144 2.3E-7 T 13-10-2018 IPR023485 Phosphotyrosine protein phosphatase I Astex_0610 1167bbbd1d3d122109fdae85847c7f92 170 Gene3D G3DSA:3.40.50.2300 6 146 3.3E-23 T 13-10-2018 Astex_0610 1167bbbd1d3d122109fdae85847c7f92 170 SUPERFAMILY SSF52788 6 143 2.09E-22 T 13-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily Astex_3682 3299c42aa34717a3d7dae2001e88bede 140 Pfam PF03994 Domain of Unknown Function (DUF350) 17 67 2.0E-9 T 13-10-2018 IPR007140 Protein of unknown function DUF350 Astex_3176 7bc13bfad42e18292e8fd3a82fd75a93 195 Gene3D G3DSA:1.10.357.10 6 178 6.4E-17 T 13-10-2018 Astex_3176 7bc13bfad42e18292e8fd3a82fd75a93 195 SUPERFAMILY SSF46689 7 67 1.13E-11 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Astex_3176 7bc13bfad42e18292e8fd3a82fd75a93 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 53 6.0E-10 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Astex_2620 90f0df02bd8a1553e70a9fcb60f8fa19 296 SUPERFAMILY SSF81452 7 292 4.71E-86 T 13-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_2620 90f0df02bd8a1553e70a9fcb60f8fa19 296 Pfam PF00510 Cytochrome c oxidase subunit III 8 119 2.0E-27 T 13-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_2620 90f0df02bd8a1553e70a9fcb60f8fa19 296 Pfam PF00510 Cytochrome c oxidase subunit III 141 292 5.0E-51 T 13-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_2620 90f0df02bd8a1553e70a9fcb60f8fa19 296 Gene3D G3DSA:1.10.287.70 4 76 1.1E-25 T 13-10-2018 Astex_2620 90f0df02bd8a1553e70a9fcb60f8fa19 296 Gene3D G3DSA:1.20.120.80 77 294 5.4E-72 T 13-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_3220 1f81b5cbb297673c64dbb831782be6a7 403 Pfam PF00072 Response regulator receiver domain 9 122 1.2E-20 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_3220 1f81b5cbb297673c64dbb831782be6a7 403 SUPERFAMILY SSF52172 6 186 1.32E-31 T 13-10-2018 IPR011006 CheY-like superfamily Astex_3220 1f81b5cbb297673c64dbb831782be6a7 403 Gene3D G3DSA:3.40.50.300 141 273 2.3E-20 T 13-10-2018 Astex_3220 1f81b5cbb297673c64dbb831782be6a7 403 Gene3D G3DSA:1.10.8.60 274 341 1.1E-16 T 13-10-2018 Astex_3220 1f81b5cbb297673c64dbb831782be6a7 403 Pfam PF02954 Bacterial regulatory protein, Fis family 361 401 1.7E-14 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Astex_3220 1f81b5cbb297673c64dbb831782be6a7 403 SUPERFAMILY SSF46689 316 403 7.62E-14 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Astex_3220 1f81b5cbb297673c64dbb831782be6a7 403 SUPERFAMILY SSF52540 142 344 3.36E-27 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_3220 1f81b5cbb297673c64dbb831782be6a7 403 SMART SM00448 6 122 2.5E-23 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_3220 1f81b5cbb297673c64dbb831782be6a7 403 Gene3D G3DSA:3.40.50.2300 3 137 9.2E-28 T 13-10-2018 Astex_3220 1f81b5cbb297673c64dbb831782be6a7 403 Gene3D G3DSA:1.10.10.60 347 403 8.0E-13 T 13-10-2018 Astex_3220 1f81b5cbb297673c64dbb831782be6a7 403 Pfam PF14532 Sigma-54 interaction domain 143 274 1.4E-16 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 Astex_3220 1f81b5cbb297673c64dbb831782be6a7 403 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 384 403 5.9E-9 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Astex_3220 1f81b5cbb297673c64dbb831782be6a7 403 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 367 384 5.9E-9 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Astex_1954 b3c5647bb0b45788bf04e4926aa889d2 493 PIRSF PIRSF000110 2 493 2.8E-157 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 Astex_1954 b3c5647bb0b45788bf04e4926aa889d2 493 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 179 185 - T 13-10-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 Astex_1954 b3c5647bb0b45788bf04e4926aa889d2 493 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 11 493 78.002 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 Astex_1954 b3c5647bb0b45788bf04e4926aa889d2 493 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 328 354 7.6E-48 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 Astex_1954 b3c5647bb0b45788bf04e4926aa889d2 493 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 239 255 7.6E-48 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 Astex_1954 b3c5647bb0b45788bf04e4926aa889d2 493 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 169 197 7.6E-48 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 Astex_1954 b3c5647bb0b45788bf04e4926aa889d2 493 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 221 238 7.6E-48 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 Astex_1954 b3c5647bb0b45788bf04e4926aa889d2 493 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 145 158 7.6E-48 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 Astex_1954 b3c5647bb0b45788bf04e4926aa889d2 493 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 13 492 1.7E-160 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 Astex_1954 b3c5647bb0b45788bf04e4926aa889d2 493 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 15 189 2.6E-48 T 13-10-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 Astex_1954 b3c5647bb0b45788bf04e4926aa889d2 493 Gene3D G3DSA:3.40.50.720 14 441 1.6E-154 T 13-10-2018 Astex_1954 b3c5647bb0b45788bf04e4926aa889d2 493 SUPERFAMILY SSF51735 10 192 1.4E-46 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_1954 b3c5647bb0b45788bf04e4926aa889d2 493 Gene3D G3DSA:3.30.360.10 179 480 1.6E-154 T 13-10-2018 Astex_1954 b3c5647bb0b45788bf04e4926aa889d2 493 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 191 491 1.0E-111 T 13-10-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 Astex_1954 b3c5647bb0b45788bf04e4926aa889d2 493 SUPERFAMILY SSF55347 179 491 3.6E-109 T 13-10-2018 Astex_2360 24095c82a9e7476ca4ef1b0152eb39d3 409 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 91 105 - T 13-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Astex_2360 24095c82a9e7476ca4ef1b0152eb39d3 409 Gene3D G3DSA:3.40.50.1100 20 216 1.4E-183 T 13-10-2018 Astex_2360 24095c82a9e7476ca4ef1b0152eb39d3 409 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 64 389 2.2E-44 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme Astex_2360 24095c82a9e7476ca4ef1b0152eb39d3 409 SUPERFAMILY SSF53686 13 400 5.76E-148 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme Astex_2360 24095c82a9e7476ca4ef1b0152eb39d3 409 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 17 401 6.0E-191 T 13-10-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Astex_2360 24095c82a9e7476ca4ef1b0152eb39d3 409 PIRSF PIRSF001413 2 408 3.4E-164 T 13-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Astex_2360 24095c82a9e7476ca4ef1b0152eb39d3 409 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 12 402 52.662 T 13-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Astex_2360 24095c82a9e7476ca4ef1b0152eb39d3 409 Gene3D G3DSA:3.40.50.1100 64 395 1.4E-183 T 13-10-2018 Astex_0631 f9c9841b47c5e8f79702e98b21da8681 534 SUPERFAMILY SSF52540 10 278 1.92E-79 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0631 f9c9841b47c5e8f79702e98b21da8681 534 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 3 531 48.283 T 13-10-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 Astex_0631 f9c9841b47c5e8f79702e98b21da8681 534 SUPERFAMILY SSF50447 263 398 2.99E-21 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Astex_0631 f9c9841b47c5e8f79702e98b21da8681 534 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 57 72 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site Astex_0631 f9c9841b47c5e8f79702e98b21da8681 534 Gene3D G3DSA:3.40.50.300 71 384 2.4E-91 T 13-10-2018 Astex_0631 f9c9841b47c5e8f79702e98b21da8681 534 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 16 160 4.9E-23 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Astex_0631 f9c9841b47c5e8f79702e98b21da8681 534 Pfam PF16658 Class II release factor RF3, C-terminal domain 392 518 1.4E-41 T 13-10-2018 IPR032090 Peptide chain release factor 3, C-terminal Astex_0631 f9c9841b47c5e8f79702e98b21da8681 534 SUPERFAMILY SSF54980 398 470 5.04E-16 T 13-10-2018 IPR035647 EF-G domain III/V-like Astex_0631 f9c9841b47c5e8f79702e98b21da8681 534 Gene3D G3DSA:3.40.50.300 109 276 2.4E-91 T 13-10-2018 Astex_0631 f9c9841b47c5e8f79702e98b21da8681 534 PRINTS PR00315 GTP-binding elongation factor signature 14 27 3.6E-13 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Astex_0631 f9c9841b47c5e8f79702e98b21da8681 534 PRINTS PR00315 GTP-binding elongation factor signature 100 111 3.6E-13 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Astex_0631 f9c9841b47c5e8f79702e98b21da8681 534 PRINTS PR00315 GTP-binding elongation factor signature 64 72 3.6E-13 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Astex_0631 f9c9841b47c5e8f79702e98b21da8681 534 PRINTS PR00315 GTP-binding elongation factor signature 136 145 3.6E-13 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Astex_0631 f9c9841b47c5e8f79702e98b21da8681 534 PRINTS PR00315 GTP-binding elongation factor signature 84 94 3.6E-13 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Astex_0631 f9c9841b47c5e8f79702e98b21da8681 534 Pfam PF00009 Elongation factor Tu GTP binding domain 12 278 4.3E-50 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Astex_0631 f9c9841b47c5e8f79702e98b21da8681 534 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 7 532 3.0E-184 T 13-10-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 Astex_0631 f9c9841b47c5e8f79702e98b21da8681 534 Gene3D G3DSA:3.30.70.3280 395 533 2.9E-45 T 13-10-2018 IPR038467 Peptide chain release factor 3, C-terminal domain superfamily Astex_1827 62d89ebb1d500aa2ca71843510c31c29 112 Pfam PF00825 Ribonuclease P 6 108 1.4E-20 T 13-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 Astex_1827 62d89ebb1d500aa2ca71843510c31c29 112 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 6 107 2.1E-13 T 13-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 Astex_1827 62d89ebb1d500aa2ca71843510c31c29 112 SUPERFAMILY SSF54211 5 108 4.8E-22 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Astex_1827 62d89ebb1d500aa2ca71843510c31c29 112 Gene3D G3DSA:3.30.230.10 3 111 4.0E-21 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Astex_1827 62d89ebb1d500aa2ca71843510c31c29 112 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 6 108 2.0E-8 T 13-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 Astex_3449 3e6c94545dd28e3c5bff68421f5ebd8a 1162 Gene3D G3DSA:3.30.70.1430 50 143 5.7E-157 T 13-10-2018 Astex_3449 3e6c94545dd28e3c5bff68421f5ebd8a 1162 Gene3D G3DSA:3.30.2090.10 189 281 5.7E-157 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Astex_3449 3e6c94545dd28e3c5bff68421f5ebd8a 1162 SUPERFAMILY SSF82693 50 143 2.75E-23 T 13-10-2018 Astex_3449 3e6c94545dd28e3c5bff68421f5ebd8a 1162 Gene3D G3DSA:3.30.2090.10 824 915 4.3E-121 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Astex_3449 3e6c94545dd28e3c5bff68421f5ebd8a 1162 PRINTS PR00702 Acriflavin resistance protein family signature 471 494 2.3E-43 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3449 3e6c94545dd28e3c5bff68421f5ebd8a 1162 PRINTS PR00702 Acriflavin resistance protein family signature 48 66 2.3E-43 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3449 3e6c94545dd28e3c5bff68421f5ebd8a 1162 PRINTS PR00702 Acriflavin resistance protein family signature 393 417 2.3E-43 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3449 3e6c94545dd28e3c5bff68421f5ebd8a 1162 PRINTS PR00702 Acriflavin resistance protein family signature 365 386 2.3E-43 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3449 3e6c94545dd28e3c5bff68421f5ebd8a 1162 PRINTS PR00702 Acriflavin resistance protein family signature 446 469 2.3E-43 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3449 3e6c94545dd28e3c5bff68421f5ebd8a 1162 PRINTS PR00702 Acriflavin resistance protein family signature 20 44 2.3E-43 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3449 3e6c94545dd28e3c5bff68421f5ebd8a 1162 PRINTS PR00702 Acriflavin resistance protein family signature 338 361 2.3E-43 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3449 3e6c94545dd28e3c5bff68421f5ebd8a 1162 SUPERFAMILY SSF82693 689 774 5.23E-11 T 13-10-2018 Astex_3449 3e6c94545dd28e3c5bff68421f5ebd8a 1162 SUPERFAMILY SSF82693 149 322 1.94E-11 T 13-10-2018 Astex_3449 3e6c94545dd28e3c5bff68421f5ebd8a 1162 Gene3D G3DSA:3.30.70.1440 778 973 4.3E-121 T 13-10-2018 Astex_3449 3e6c94545dd28e3c5bff68421f5ebd8a 1162 Gene3D G3DSA:1.20.1640.10 20 503 5.7E-157 T 13-10-2018 Astex_3449 3e6c94545dd28e3c5bff68421f5ebd8a 1162 SUPERFAMILY SSF82866 300 499 4.84E-44 T 13-10-2018 Astex_3449 3e6c94545dd28e3c5bff68421f5ebd8a 1162 SUPERFAMILY SSF82714 825 914 1.1E-11 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Astex_3449 3e6c94545dd28e3c5bff68421f5ebd8a 1162 SUPERFAMILY SSF82866 912 1135 7.59E-49 T 13-10-2018 Astex_3449 3e6c94545dd28e3c5bff68421f5ebd8a 1162 Gene3D G3DSA:3.30.70.1430 690 777 4.3E-121 T 13-10-2018 Astex_3449 3e6c94545dd28e3c5bff68421f5ebd8a 1162 Gene3D G3DSA:3.30.70.1320 144 333 5.7E-157 T 13-10-2018 Astex_3449 3e6c94545dd28e3c5bff68421f5ebd8a 1162 Gene3D G3DSA:1.20.1640.10 504 547 5.7E-157 T 13-10-2018 Astex_3449 3e6c94545dd28e3c5bff68421f5ebd8a 1162 SUPERFAMILY SSF82714 192 274 1.83E-14 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Astex_3449 3e6c94545dd28e3c5bff68421f5ebd8a 1162 Pfam PF00873 AcrB/AcrD/AcrF family 656 1133 1.8E-96 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3449 3e6c94545dd28e3c5bff68421f5ebd8a 1162 Pfam PF00873 AcrB/AcrD/AcrF family 14 510 2.5E-125 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3449 3e6c94545dd28e3c5bff68421f5ebd8a 1162 Gene3D G3DSA:1.20.1640.10 656 1130 4.3E-121 T 13-10-2018 Astex_1789 98040a2dc1b50e5ffecacc985e1c9902 65 Pfam PF01632 Ribosomal protein L35 3 61 2.9E-18 T 13-10-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_1789 98040a2dc1b50e5ffecacc985e1c9902 65 Gene3D G3DSA:2.40.50.530 1 65 4.1E-21 T 13-10-2018 Astex_1789 98040a2dc1b50e5ffecacc985e1c9902 65 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 14.737 T 13-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 Astex_1789 98040a2dc1b50e5ffecacc985e1c9902 65 PRINTS PR00064 Ribosomal protein L35 signature 3 20 8.1E-7 T 13-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 Astex_1789 98040a2dc1b50e5ffecacc985e1c9902 65 PRINTS PR00064 Ribosomal protein L35 signature 21 35 8.1E-7 T 13-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 Astex_1789 98040a2dc1b50e5ffecacc985e1c9902 65 SUPERFAMILY SSF143034 3 64 3.92E-20 T 13-10-2018 IPR037229 Ribosomal protein L35 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_1789 98040a2dc1b50e5ffecacc985e1c9902 65 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 3 64 1.4E-18 T 13-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 Astex_1789 98040a2dc1b50e5ffecacc985e1c9902 65 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 13-10-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_2230 67551f00be5ecae51ae0196745641faf 572 Gene3D G3DSA:3.40.50.620 195 519 7.1E-25 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Astex_2230 67551f00be5ecae51ae0196745641faf 572 Gene3D G3DSA:3.60.20.10 73 180 1.5E-6 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Astex_2230 67551f00be5ecae51ae0196745641faf 572 SUPERFAMILY SSF56235 89 179 2.23E-8 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Astex_2230 67551f00be5ecae51ae0196745641faf 572 SUPERFAMILY SSF52402 196 534 2.72E-30 T 13-10-2018 Astex_2230 67551f00be5ecae51ae0196745641faf 572 Pfam PF00733 Asparagine synthase 204 365 6.3E-10 T 13-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 Astex_2230 67551f00be5ecae51ae0196745641faf 572 Pfam PF00733 Asparagine synthase 448 529 4.8E-6 T 13-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 Astex_0709 33a8696c32c51082c2d24039d66b92ec 471 Gene3D G3DSA:3.30.499.10 329 471 3.7E-50 T 13-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 Astex_0709 33a8696c32c51082c2d24039d66b92ec 471 Gene3D G3DSA:3.30.499.20 6 293 3.7E-95 T 13-10-2018 Astex_0709 33a8696c32c51082c2d24039d66b92ec 471 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 3 466 53.093 T 13-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 Astex_0709 33a8696c32c51082c2d24039d66b92ec 471 Pfam PF00330 Aconitase family (aconitate hydratase) 9 457 5.3E-147 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Astex_0709 33a8696c32c51082c2d24039d66b92ec 471 SUPERFAMILY SSF53732 4 466 1.44E-155 T 13-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 Astex_0709 33a8696c32c51082c2d24039d66b92ec 471 ProSitePatterns PS00450 Aconitase family signature 1. 339 355 - T 13-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 Astex_0709 33a8696c32c51082c2d24039d66b92ec 471 ProSitePatterns PS01244 Aconitase family signature 2. 399 412 - T 13-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 Astex_0709 33a8696c32c51082c2d24039d66b92ec 471 PRINTS PR00415 Aconitase family signature 399 412 3.2E-40 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Astex_0709 33a8696c32c51082c2d24039d66b92ec 471 PRINTS PR00415 Aconitase family signature 115 123 3.2E-40 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Astex_0709 33a8696c32c51082c2d24039d66b92ec 471 PRINTS PR00415 Aconitase family signature 126 139 3.2E-40 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Astex_0709 33a8696c32c51082c2d24039d66b92ec 471 PRINTS PR00415 Aconitase family signature 140 155 3.2E-40 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Astex_0709 33a8696c32c51082c2d24039d66b92ec 471 PRINTS PR00415 Aconitase family signature 293 307 3.2E-40 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Astex_0709 33a8696c32c51082c2d24039d66b92ec 471 PRINTS PR00415 Aconitase family signature 343 354 3.2E-40 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Astex_0709 33a8696c32c51082c2d24039d66b92ec 471 PRINTS PR00415 Aconitase family signature 202 215 3.2E-40 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Astex_0709 33a8696c32c51082c2d24039d66b92ec 471 PRINTS PR00415 Aconitase family signature 216 229 3.2E-40 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Astex_0709 33a8696c32c51082c2d24039d66b92ec 471 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 4 465 1.1E-190 T 13-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 Astex_2793 dc5fbf2d332f1b1f90fdff8555f4f44b 213 Hamap MF_00328 Guanylate kinase [gmk]. 8 192 35.652 T 13-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 Astex_2793 dc5fbf2d332f1b1f90fdff8555f4f44b 213 Gene3D G3DSA:3.40.50.300 14 187 1.0E-63 T 13-10-2018 Astex_2793 dc5fbf2d332f1b1f90fdff8555f4f44b 213 ProSitePatterns PS00856 Guanylate kinase-like signature. 44 61 - T 13-10-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 Astex_2793 dc5fbf2d332f1b1f90fdff8555f4f44b 213 SUPERFAMILY SSF52540 9 192 1.23E-64 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2793 dc5fbf2d332f1b1f90fdff8555f4f44b 213 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 11 189 2.8E-70 T 13-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 Astex_2793 dc5fbf2d332f1b1f90fdff8555f4f44b 213 Pfam PF00625 Guanylate kinase 12 187 1.3E-44 T 13-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit Astex_2793 dc5fbf2d332f1b1f90fdff8555f4f44b 213 Gene3D G3DSA:3.30.63.10 41 100 1.0E-63 T 13-10-2018 Astex_2793 dc5fbf2d332f1b1f90fdff8555f4f44b 213 SMART SM00072 9 192 2.7E-60 T 13-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit Astex_3126 048d03e0cf40c9212eb162f3dcd4b824 555 Gene3D G3DSA:3.30.9.90 83 456 2.6E-188 T 13-10-2018 Astex_3126 048d03e0cf40c9212eb162f3dcd4b824 555 Gene3D G3DSA:3.30.70.20 457 550 3.2E-39 T 13-10-2018 Astex_3126 048d03e0cf40c9212eb162f3dcd4b824 555 Gene3D G3DSA:3.50.50.60 11 388 2.6E-188 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_3126 048d03e0cf40c9212eb162f3dcd4b824 555 SUPERFAMILY SSF54373 214 310 4.32E-38 T 13-10-2018 Astex_3126 048d03e0cf40c9212eb162f3dcd4b824 555 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 13 35 3.2E-6 T 13-10-2018 Astex_3126 048d03e0cf40c9212eb162f3dcd4b824 555 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 182 197 3.2E-6 T 13-10-2018 Astex_3126 048d03e0cf40c9212eb162f3dcd4b824 555 SUPERFAMILY SSF51905 6 454 4.05E-53 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_3126 048d03e0cf40c9212eb162f3dcd4b824 555 SUPERFAMILY SSF54862 456 555 6.58E-31 T 13-10-2018 Astex_3126 048d03e0cf40c9212eb162f3dcd4b824 555 Pfam PF13450 NAD(P)-binding Rossmann-like domain 16 61 2.4E-7 T 13-10-2018 Astex_3126 048d03e0cf40c9212eb162f3dcd4b824 555 Pfam PF05187 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 452 552 5.2E-51 T 13-10-2018 Astex_2788 f69c8c40b6fcb8400b04f1960c25ac35 246 SUPERFAMILY SSF51735 6 245 1.34E-80 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_2788 f69c8c40b6fcb8400b04f1960c25ac35 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 1.4E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2788 f69c8c40b6fcb8400b04f1960c25ac35 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 1.4E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2788 f69c8c40b6fcb8400b04f1960c25ac35 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 1.4E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2788 f69c8c40b6fcb8400b04f1960c25ac35 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 6.7E-41 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2788 f69c8c40b6fcb8400b04f1960c25ac35 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 6.7E-41 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2788 f69c8c40b6fcb8400b04f1960c25ac35 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 6.7E-41 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2788 f69c8c40b6fcb8400b04f1960c25ac35 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 6.7E-41 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2788 f69c8c40b6fcb8400b04f1960c25ac35 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 6.7E-41 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2788 f69c8c40b6fcb8400b04f1960c25ac35 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 6.7E-41 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2788 f69c8c40b6fcb8400b04f1960c25ac35 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Astex_2788 f69c8c40b6fcb8400b04f1960c25ac35 246 Gene3D G3DSA:3.40.50.720 1 246 3.2E-81 T 13-10-2018 Astex_2788 f69c8c40b6fcb8400b04f1960c25ac35 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 243 1.0E-60 T 13-10-2018 Astex_2788 f69c8c40b6fcb8400b04f1960c25ac35 246 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 9 244 2.8E-95 T 13-10-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 Astex_2788 f69c8c40b6fcb8400b04f1960c25ac35 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 189 9.3E-8 T 13-10-2018 Astex_2093 e5eb90c96da3cc3d3065f23a453c5314 481 SUPERFAMILY SSF46548 12 158 6.8E-33 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Astex_2093 e5eb90c96da3cc3d3065f23a453c5314 481 TIGRFAM TIGR01318 gltD_gamma_fam: glutamate synthase, small subunit 8 470 2.2E-161 T 13-10-2018 IPR006006 Glutamate synthase, NADH/NADPH, small subunit 2 GO:0006537|GO:0016639 Astex_2093 e5eb90c96da3cc3d3065f23a453c5314 481 Gene3D G3DSA:1.10.1060.10 2 147 7.7E-34 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Astex_2093 e5eb90c96da3cc3d3065f23a453c5314 481 PRINTS PR00419 Adrenodoxin reductase family signature 172 185 1.3E-32 T 13-10-2018 Astex_2093 e5eb90c96da3cc3d3065f23a453c5314 481 PRINTS PR00419 Adrenodoxin reductase family signature 326 339 1.3E-32 T 13-10-2018 Astex_2093 e5eb90c96da3cc3d3065f23a453c5314 481 PRINTS PR00419 Adrenodoxin reductase family signature 149 171 1.3E-32 T 13-10-2018 Astex_2093 e5eb90c96da3cc3d3065f23a453c5314 481 PRINTS PR00419 Adrenodoxin reductase family signature 214 224 1.3E-32 T 13-10-2018 Astex_2093 e5eb90c96da3cc3d3065f23a453c5314 481 PRINTS PR00419 Adrenodoxin reductase family signature 292 306 1.3E-32 T 13-10-2018 Astex_2093 e5eb90c96da3cc3d3065f23a453c5314 481 Gene3D G3DSA:3.50.50.60 374 473 1.0E-7 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_2093 e5eb90c96da3cc3d3065f23a453c5314 481 SUPERFAMILY SSF51971 148 402 4.47E-65 T 13-10-2018 Astex_2093 e5eb90c96da3cc3d3065f23a453c5314 481 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 24 135 1.1E-38 T 13-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 Astex_2093 e5eb90c96da3cc3d3065f23a453c5314 481 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 149 458 6.7E-34 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Astex_2093 e5eb90c96da3cc3d3065f23a453c5314 481 SUPERFAMILY SSF51971 337 469 2.71E-9 T 13-10-2018 Astex_2093 e5eb90c96da3cc3d3065f23a453c5314 481 Gene3D G3DSA:3.50.50.60 274 373 8.1E-20 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_2093 e5eb90c96da3cc3d3065f23a453c5314 481 Gene3D G3DSA:3.50.50.60 148 273 1.6E-29 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_3422 23e2749f0246ea30b1982b88671012e0 1003 Gene3D G3DSA:2.40.170.20 386 1003 1.5E-39 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_3422 23e2749f0246ea30b1982b88671012e0 1003 Gene3D G3DSA:3.55.50.30 27 130 1.2E-18 T 13-10-2018 Astex_3422 23e2749f0246ea30b1982b88671012e0 1003 Gene3D G3DSA:2.170.130.10 131 278 5.5E-17 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_3422 23e2749f0246ea30b1982b88671012e0 1003 Pfam PF00593 TonB dependent receptor 525 1002 6.2E-34 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_3422 23e2749f0246ea30b1982b88671012e0 1003 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 143 1003 8.4E-190 T 13-10-2018 IPR010104 Bacterial TonB-dependent receptor Astex_3422 23e2749f0246ea30b1982b88671012e0 1003 SUPERFAMILY SSF56935 143 1003 5.13E-81 T 13-10-2018 Astex_3422 23e2749f0246ea30b1982b88671012e0 1003 Pfam PF07660 Secretin and TonB N terminus short domain 63 106 1.3E-8 T 13-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 Astex_3422 23e2749f0246ea30b1982b88671012e0 1003 Pfam PF07715 TonB-dependent Receptor Plug Domain 159 273 7.2E-14 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_3422 23e2749f0246ea30b1982b88671012e0 1003 SMART SM00965 57 108 8.4E-11 T 13-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 Astex_2280 1ace025a76cfbcab1600d33b03781e66 411 Pfam PF13242 HAD-hyrolase-like 351 399 7.1E-9 T 13-10-2018 Astex_2280 1ace025a76cfbcab1600d33b03781e66 411 Gene3D G3DSA:3.90.550.10 10 245 5.4E-51 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_2280 1ace025a76cfbcab1600d33b03781e66 411 Gene3D G3DSA:3.40.50.1000 246 407 3.3E-45 T 13-10-2018 IPR023214 HAD superfamily Astex_2280 1ace025a76cfbcab1600d33b03781e66 411 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 246 393 2.1E-33 T 13-10-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 Astex_2280 1ace025a76cfbcab1600d33b03781e66 411 SUPERFAMILY SSF53448 14 242 8.55E-46 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_2280 1ace025a76cfbcab1600d33b03781e66 411 SUPERFAMILY SSF56784 241 401 2.85E-37 T 13-10-2018 IPR036412 HAD-like superfamily Astex_2280 1ace025a76cfbcab1600d33b03781e66 411 Pfam PF00483 Nucleotidyl transferase 14 236 1.0E-22 T 13-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Astex_2280 1ace025a76cfbcab1600d33b03781e66 411 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 247 395 3.6E-29 T 13-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 Astex_0169 12facc1bbbf2f01c34d346ab499c2466 296 Pfam PF03471 Transporter associated domain 203 285 6.3E-18 T 13-10-2018 IPR005170 Transporter-associated domain Astex_0169 12facc1bbbf2f01c34d346ab499c2466 296 SMART SM01091 202 286 8.0E-20 T 13-10-2018 IPR005170 Transporter-associated domain Astex_0169 12facc1bbbf2f01c34d346ab499c2466 296 Gene3D G3DSA:3.30.465.10 196 292 2.6E-21 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 Astex_0169 12facc1bbbf2f01c34d346ab499c2466 296 SMART SM00116 68 117 0.039 T 13-10-2018 IPR000644 CBS domain Astex_0169 12facc1bbbf2f01c34d346ab499c2466 296 SMART SM00116 138 186 3.0 T 13-10-2018 IPR000644 CBS domain Astex_0169 12facc1bbbf2f01c34d346ab499c2466 296 SUPERFAMILY SSF54631 54 197 6.06E-32 T 13-10-2018 Astex_0169 12facc1bbbf2f01c34d346ab499c2466 296 Pfam PF00571 CBS domain 136 186 2.3E-5 T 13-10-2018 IPR000644 CBS domain Astex_0169 12facc1bbbf2f01c34d346ab499c2466 296 Pfam PF00571 CBS domain 59 117 2.7E-6 T 13-10-2018 IPR000644 CBS domain Astex_0169 12facc1bbbf2f01c34d346ab499c2466 296 SUPERFAMILY SSF56176 200 288 1.28E-17 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 Astex_0169 12facc1bbbf2f01c34d346ab499c2466 296 Gene3D G3DSA:3.10.580.10 39 195 5.9E-50 T 13-10-2018 Astex_2754 904e987cf6cd5c56bc136f5791b087c1 170 Gene3D G3DSA:3.40.30.10 16 169 3.2E-43 T 13-10-2018 Astex_2754 904e987cf6cd5c56bc136f5791b087c1 170 SUPERFAMILY SSF52833 22 167 1.82E-46 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Astex_2754 904e987cf6cd5c56bc136f5791b087c1 170 PIRSF PIRSF000239 20 167 9.9E-23 T 13-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 Astex_2754 904e987cf6cd5c56bc136f5791b087c1 170 Pfam PF00578 AhpC/TSA family 23 147 4.9E-30 T 13-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 Astex_0707 2917ee2c6fd56568350fb354f474a74c 353 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 5 345 1.7E-140 T 13-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 Astex_0707 2917ee2c6fd56568350fb354f474a74c 353 SUPERFAMILY SSF53659 3 345 9.72E-112 T 13-10-2018 Astex_0707 2917ee2c6fd56568350fb354f474a74c 353 Gene3D G3DSA:3.40.718.10 1 351 1.4E-133 T 13-10-2018 Astex_0707 2917ee2c6fd56568350fb354f474a74c 353 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 341 5.4E-125 T 13-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 Astex_0707 2917ee2c6fd56568350fb354f474a74c 353 SMART SM01329 5 342 5.6E-172 T 13-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 Astex_0707 2917ee2c6fd56568350fb354f474a74c 353 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 4 346 45.197 T 13-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 Astex_0707 2917ee2c6fd56568350fb354f474a74c 353 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 238 257 - T 13-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 Astex_0176 f821348d8edf1d50a658620d19f84d42 546 Gene3D G3DSA:3.30.1480.10 10 137 2.0E-33 T 13-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 Astex_0176 f821348d8edf1d50a658620d19f84d42 546 Gene3D G3DSA:2.40.50.140 145 207 1.4E-23 T 13-10-2018 Astex_0176 f821348d8edf1d50a658620d19f84d42 546 SMART SM00316 143 209 9.2E-10 T 13-10-2018 IPR022967 RNA-binding domain, S1 Astex_0176 f821348d8edf1d50a658620d19f84d42 546 SUPERFAMILY SSF54814 288 351 7.85E-17 T 13-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 Astex_0176 f821348d8edf1d50a658620d19f84d42 546 Gene3D G3DSA:3.30.300.20 287 355 2.8E-28 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta Astex_0176 f821348d8edf1d50a658620d19f84d42 546 Pfam PF00575 S1 RNA binding domain 141 203 1.9E-5 T 13-10-2018 IPR003029 S1 domain GO:0003676 Astex_0176 f821348d8edf1d50a658620d19f84d42 546 SUPERFAMILY SSF47794 358 423 3.14E-15 T 13-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 Astex_0176 f821348d8edf1d50a658620d19f84d42 546 Pfam PF13184 NusA-like KH domain 239 305 1.6E-28 T 13-10-2018 IPR025249 KH domain, NusA-like GO:0003723 Astex_0176 f821348d8edf1d50a658620d19f84d42 546 SUPERFAMILY SSF50249 141 208 2.11E-19 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Astex_0176 f821348d8edf1d50a658620d19f84d42 546 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 375 423 2.6E-21 T 13-10-2018 IPR010214 Transcription termination factor NusA, C-terminal duplication Astex_0176 f821348d8edf1d50a658620d19f84d42 546 SUPERFAMILY SSF54814 210 286 4.32E-30 T 13-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 Astex_0176 f821348d8edf1d50a658620d19f84d42 546 Gene3D G3DSA:3.30.300.20 208 286 5.1E-33 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta Astex_0176 f821348d8edf1d50a658620d19f84d42 546 SUPERFAMILY SSF69705 11 135 4.32E-30 T 13-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 Astex_0176 f821348d8edf1d50a658620d19f84d42 546 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 12 352 3.0E-126 T 13-10-2018 IPR010213 Transcription termination factor NusA GO:0003723 Astex_0176 f821348d8edf1d50a658620d19f84d42 546 Pfam PF14520 Helix-hairpin-helix domain 378 421 4.1E-4 T 13-10-2018 Astex_0176 f821348d8edf1d50a658620d19f84d42 546 Pfam PF14520 Helix-hairpin-helix domain 441 476 6.7E-5 T 13-10-2018 Astex_0176 f821348d8edf1d50a658620d19f84d42 546 Pfam PF08529 NusA N-terminal domain 12 134 3.3E-27 T 13-10-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 Astex_0176 f821348d8edf1d50a658620d19f84d42 546 SMART SM00322 239 302 26.0 T 13-10-2018 IPR004087 K Homology domain GO:0003676 Astex_0176 f821348d8edf1d50a658620d19f84d42 546 SMART SM00322 310 383 1.9E-5 T 13-10-2018 IPR004087 K Homology domain GO:0003676 Astex_0176 f821348d8edf1d50a658620d19f84d42 546 Gene3D G3DSA:1.10.150.20 364 430 6.2E-22 T 13-10-2018 Astex_0176 f821348d8edf1d50a658620d19f84d42 546 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 10 419 29.701 T 13-10-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 Astex_0176 f821348d8edf1d50a658620d19f84d42 546 Gene3D G3DSA:1.10.150.20 440 486 9.9E-7 T 13-10-2018 Astex_0176 f821348d8edf1d50a658620d19f84d42 546 SUPERFAMILY SSF158702 421 488 3.92E-5 T 13-10-2018 Astex_2092 fa09c1ba9dab3eea794032776b8eb650 1506 Pfam PF00310 Glutamine amidotransferases class-II 34 452 2.1E-150 T 13-10-2018 IPR017932 Glutamine amidotransferase type 2 domain Astex_2092 fa09c1ba9dab3eea794032776b8eb650 1506 SUPERFAMILY SSF56235 34 454 1.97E-136 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Astex_2092 fa09c1ba9dab3eea794032776b8eb650 1506 Pfam PF01645 Conserved region in glutamate synthase 823 1193 7.3E-146 T 13-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 Astex_2092 fa09c1ba9dab3eea794032776b8eb650 1506 SUPERFAMILY SSF69336 1246 1494 3.53E-79 T 13-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 Astex_2092 fa09c1ba9dab3eea794032776b8eb650 1506 Gene3D G3DSA:2.160.20.60 1244 1506 7.1E-96 T 13-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 Astex_2092 fa09c1ba9dab3eea794032776b8eb650 1506 Pfam PF01493 GXGXG motif 1271 1453 9.3E-68 T 13-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 Astex_2092 fa09c1ba9dab3eea794032776b8eb650 1506 Gene3D G3DSA:3.20.20.70 506 1208 0.0 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_2092 fa09c1ba9dab3eea794032776b8eb650 1506 Gene3D G3DSA:3.60.20.10 34 568 0.0 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Astex_2092 fa09c1ba9dab3eea794032776b8eb650 1506 Gene3D G3DSA:3.20.20.70 457 822 0.0 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_2092 fa09c1ba9dab3eea794032776b8eb650 1506 Pfam PF04898 Glutamate synthase central domain 480 766 3.4E-91 T 13-10-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 Astex_2092 fa09c1ba9dab3eea794032776b8eb650 1506 SUPERFAMILY SSF51395 458 1228 7.33E-242 T 13-10-2018 Astex_1884 34f6cf68cdd81bdb557e20795cfbd524 485 Gene3D G3DSA:3.30.1490.270 350 410 4.2E-26 T 13-10-2018 Astex_1884 34f6cf68cdd81bdb557e20795cfbd524 485 Gene3D G3DSA:3.40.50.11290 216 313 2.1E-43 T 13-10-2018 Astex_1884 34f6cf68cdd81bdb557e20795cfbd524 485 PIRSF PIRSF005522 1 480 1.2E-222 T 13-10-2018 IPR016450 Uncharacterised conserved protein UCP005522 Astex_1884 34f6cf68cdd81bdb557e20795cfbd524 485 SUPERFAMILY SSF56059 36 468 1.37E-63 T 13-10-2018 Astex_1884 34f6cf68cdd81bdb557e20795cfbd524 485 Pfam PF14403 Circularly permuted ATP-grasp type 2 78 453 3.8E-162 T 13-10-2018 IPR025841 Circularly permuted ATP-grasp type 2 Astex_1084 6fa7bb842b18fb683862c8cb922b80d1 335 Pfam PF07728 AAA domain (dynein-related subfamily) 73 195 1.4E-11 T 13-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 Astex_1084 6fa7bb842b18fb683862c8cb922b80d1 335 TIGRFAM TIGR01650 PD_CobS: cobaltochelatase, CobS subunit 10 333 1.9E-192 T 13-10-2018 IPR006537 Cobaltochelatase subunit CobS KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 Astex_1084 6fa7bb842b18fb683862c8cb922b80d1 335 Gene3D G3DSA:3.40.50.300 58 236 7.0E-23 T 13-10-2018 Astex_1084 6fa7bb842b18fb683862c8cb922b80d1 335 Pfam PF12556 Cobaltochelatase CobS subunit N terminal 17 46 4.0E-16 T 13-10-2018 IPR025865 Cobaltochelatase subunit CobS N-terminal domain KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 Astex_1084 6fa7bb842b18fb683862c8cb922b80d1 335 SUPERFAMILY SSF52540 60 291 3.55E-31 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0602 7f4e017241d7b6221b5554df25f6d98e 338 Gene3D G3DSA:3.20.20.80 10 338 1.5E-85 T 13-10-2018 Astex_0602 7f4e017241d7b6221b5554df25f6d98e 338 Pfam PF00331 Glycosyl hydrolase family 10 28 336 3.8E-77 T 13-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 Astex_0602 7f4e017241d7b6221b5554df25f6d98e 338 SUPERFAMILY SSF51445 27 338 1.3E-84 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_0602 7f4e017241d7b6221b5554df25f6d98e 338 PRINTS PR00134 Glycosyl hydrolase family 10 signature 92 104 2.1E-9 T 13-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 Astex_0602 7f4e017241d7b6221b5554df25f6d98e 338 PRINTS PR00134 Glycosyl hydrolase family 10 signature 181 192 2.1E-9 T 13-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 Astex_0602 7f4e017241d7b6221b5554df25f6d98e 338 PRINTS PR00134 Glycosyl hydrolase family 10 signature 136 147 2.1E-9 T 13-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 Astex_0602 7f4e017241d7b6221b5554df25f6d98e 338 PRINTS PR00134 Glycosyl hydrolase family 10 signature 210 222 2.1E-9 T 13-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 Astex_0602 7f4e017241d7b6221b5554df25f6d98e 338 SMART SM00633 61 338 6.5E-64 T 13-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 Astex_3282 80493db96ca863717635f36c1199309e 773 Pfam PF00563 EAL domain 520 753 3.8E-67 T 13-10-2018 IPR001633 EAL domain Astex_3282 80493db96ca863717635f36c1199309e 773 Pfam PF05226 CHASE2 domain 26 248 2.0E-16 T 13-10-2018 IPR007890 CHASE2 Astex_3282 80493db96ca863717635f36c1199309e 773 Gene3D G3DSA:3.20.20.450 515 767 1.0E-81 T 13-10-2018 IPR035919 EAL domain superfamily Astex_3282 80493db96ca863717635f36c1199309e 773 SMART SM01080 36 294 8.3E-18 T 13-10-2018 IPR007890 CHASE2 Astex_3282 80493db96ca863717635f36c1199309e 773 SMART SM00052 513 758 5.3E-81 T 13-10-2018 IPR001633 EAL domain Astex_3282 80493db96ca863717635f36c1199309e 773 Gene3D G3DSA:3.30.70.270 367 514 2.4E-5 T 13-10-2018 Astex_3282 80493db96ca863717635f36c1199309e 773 SUPERFAMILY SSF141868 519 763 1.44E-76 T 13-10-2018 IPR035919 EAL domain superfamily Astex_2814 87945e354a03a19253aa2bfd8e9e952a 102 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 3 102 20.566 T 13-10-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 Astex_2814 87945e354a03a19253aa2bfd8e9e952a 102 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 8 96 1.5E-24 T 13-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like Astex_3848 cfaa4d86c75c136db9cb60229a70361c 786 SUPERFAMILY SSF56784 475 779 2.25E-54 T 13-10-2018 IPR036412 HAD-like superfamily Astex_3848 cfaa4d86c75c136db9cb60229a70361c 786 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 597 608 2.3E-27 T 13-10-2018 Astex_3848 cfaa4d86c75c136db9cb60229a70361c 786 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 619 629 2.3E-27 T 13-10-2018 Astex_3848 cfaa4d86c75c136db9cb60229a70361c 786 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 672 691 2.3E-27 T 13-10-2018 Astex_3848 cfaa4d86c75c136db9cb60229a70361c 786 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 477 491 2.3E-27 T 13-10-2018 Astex_3848 cfaa4d86c75c136db9cb60229a70361c 786 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 325 339 2.3E-27 T 13-10-2018 Astex_3848 cfaa4d86c75c136db9cb60229a70361c 786 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 695 707 2.3E-27 T 13-10-2018 Astex_3848 cfaa4d86c75c136db9cb60229a70361c 786 SUPERFAMILY SSF81665 238 760 3.27E-16 T 13-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 Astex_3848 cfaa4d86c75c136db9cb60229a70361c 786 Gene3D G3DSA:3.40.50.1000 458 723 2.1E-84 T 13-10-2018 IPR023214 HAD superfamily Astex_3848 cfaa4d86c75c136db9cb60229a70361c 786 SUPERFAMILY SSF81653 278 374 3.27E-29 T 13-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 Astex_3848 cfaa4d86c75c136db9cb60229a70361c 786 Gene3D G3DSA:2.70.150.20 269 380 2.5E-44 T 13-10-2018 Astex_3848 cfaa4d86c75c136db9cb60229a70361c 786 Pfam PF00122 E1-E2 ATPase 275 457 5.3E-60 T 13-10-2018 Astex_3848 cfaa4d86c75c136db9cb60229a70361c 786 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 248 750 1.3E-88 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Astex_3848 cfaa4d86c75c136db9cb60229a70361c 786 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 205 780 1.7E-187 T 13-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 Astex_3848 cfaa4d86c75c136db9cb60229a70361c 786 PRINTS PR00943 Copper-transporting ATPase signature 245 264 1.1E-10 T 13-10-2018 Astex_3848 cfaa4d86c75c136db9cb60229a70361c 786 PRINTS PR00943 Copper-transporting ATPase signature 649 666 1.1E-10 T 13-10-2018 Astex_3848 cfaa4d86c75c136db9cb60229a70361c 786 PRINTS PR00943 Copper-transporting ATPase signature 398 412 1.1E-10 T 13-10-2018 Astex_3848 cfaa4d86c75c136db9cb60229a70361c 786 PRINTS PR00943 Copper-transporting ATPase signature 190 209 1.1E-10 T 13-10-2018 Astex_3848 cfaa4d86c75c136db9cb60229a70361c 786 PRINTS PR00943 Copper-transporting ATPase signature 265 283 1.1E-10 T 13-10-2018 Astex_3848 cfaa4d86c75c136db9cb60229a70361c 786 PRINTS PR00943 Copper-transporting ATPase signature 460 475 1.1E-10 T 13-10-2018 Astex_3848 cfaa4d86c75c136db9cb60229a70361c 786 PRINTS PR00943 Copper-transporting ATPase signature 745 759 1.1E-10 T 13-10-2018 Astex_3848 cfaa4d86c75c136db9cb60229a70361c 786 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 479 485 - T 13-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 Astex_3848 cfaa4d86c75c136db9cb60229a70361c 786 Pfam PF00702 haloacid dehalogenase-like hydrolase 473 685 4.3E-41 T 13-10-2018 Astex_3848 cfaa4d86c75c136db9cb60229a70361c 786 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 187 782 2.7E-179 T 13-10-2018 Astex_3848 cfaa4d86c75c136db9cb60229a70361c 786 Gene3D G3DSA:3.40.1110.10 488 604 2.1E-84 T 13-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 Astex_0195 617880b04655c0f560cbb0f6d944f5b2 1655 SUPERFAMILY SSF48239 1187 1451 7.68E-33 T 13-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid Astex_0195 617880b04655c0f560cbb0f6d944f5b2 1655 Pfam PF11974 Alpha-2-macroglobulin MG1 domain 302 402 1.5E-19 T 13-10-2018 Astex_0195 617880b04655c0f560cbb0f6d944f5b2 1655 Gene3D G3DSA:2.60.40.1930 416 516 5.7E-7 T 13-10-2018 Astex_0195 617880b04655c0f560cbb0f6d944f5b2 1655 Pfam PF01835 MG2 domain 418 512 2.4E-19 T 13-10-2018 IPR002890 Alpha-2-macroglobulin, N-terminal GO:0004866 Astex_0195 617880b04655c0f560cbb0f6d944f5b2 1655 SMART SM01359 774 925 8.5E-23 T 13-10-2018 IPR011625 Alpha-2-macroglobulin, N-terminal 2 Astex_0195 617880b04655c0f560cbb0f6d944f5b2 1655 Gene3D G3DSA:1.50.10.20 1185 1452 1.5E-23 T 13-10-2018 Astex_0195 617880b04655c0f560cbb0f6d944f5b2 1655 Pfam PF00207 Alpha-2-macroglobulin family 985 1064 3.3E-7 T 13-10-2018 IPR001599 Alpha-2-macroglobulin GO:0004866 Astex_0195 617880b04655c0f560cbb0f6d944f5b2 1655 PIRSF PIRSF038980 6 1655 0.0 T 13-10-2018 IPR026284 Alpha-2-macroglobulin domain protein, bacteria Astex_0195 617880b04655c0f560cbb0f6d944f5b2 1655 Pfam PF07703 Alpha-2-macroglobulin family N-terminal region 777 925 3.2E-11 T 13-10-2018 IPR011625 Alpha-2-macroglobulin, N-terminal 2 Astex_0195 617880b04655c0f560cbb0f6d944f5b2 1655 SMART SM01360 984 1073 8.8E-23 T 13-10-2018 IPR001599 Alpha-2-macroglobulin GO:0004866 Astex_3464 492271f22f738600af83ed7ade8f93d7 643 SMART SM01340 219 337 6.5E-57 T 13-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 Astex_3464 492271f22f738600af83ed7ade8f93d7 643 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 220 336 9.1E-36 T 13-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 Astex_3464 492271f22f738600af83ed7ade8f93d7 643 Gene3D G3DSA:3.30.565.10 3 211 2.4E-58 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_3464 492271f22f738600af83ed7ade8f93d7 643 SUPERFAMILY SSF118116 452 642 6.8E-59 T 13-10-2018 IPR037198 MutL, C-terminal domain superfamily Astex_3464 492271f22f738600af83ed7ade8f93d7 643 SUPERFAMILY SSF55874 2 209 3.01E-46 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_3464 492271f22f738600af83ed7ade8f93d7 643 Pfam PF08676 MutL C terminal dimerisation domain 453 600 2.1E-48 T 13-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 Astex_3464 492271f22f738600af83ed7ade8f93d7 643 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 25 131 6.0E-11 T 13-10-2018 Astex_3464 492271f22f738600af83ed7ade8f93d7 643 Gene3D G3DSA:2.30.42.20 459 637 2.4E-60 T 13-10-2018 Astex_3464 492271f22f738600af83ed7ade8f93d7 643 SMART SM00853 457 600 9.3E-53 T 13-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 Astex_3464 492271f22f738600af83ed7ade8f93d7 643 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 3 317 2.0E-86 T 13-10-2018 IPR002099 DNA mismatch repair protein family, N-terminal GO:0005524|GO:0006298|GO:0030983 Astex_3464 492271f22f738600af83ed7ade8f93d7 643 SUPERFAMILY SSF54211 212 337 5.31E-34 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Astex_3464 492271f22f738600af83ed7ade8f93d7 643 Gene3D G3DSA:3.30.1370.100 500 595 2.4E-60 T 13-10-2018 Astex_3464 492271f22f738600af83ed7ade8f93d7 643 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 98 104 - T 13-10-2018 IPR014762 DNA mismatch repair, conserved site Astex_3464 492271f22f738600af83ed7ade8f93d7 643 Gene3D G3DSA:3.30.230.10 224 336 6.7E-33 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Astex_3464 492271f22f738600af83ed7ade8f93d7 643 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 2 640 27.556 T 13-10-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 Astex_0275 6b4795de26095ef42df94b9edb85aa75 351 Gene3D G3DSA:3.40.190.10 124 235 7.3E-85 T 13-10-2018 Astex_0275 6b4795de26095ef42df94b9edb85aa75 351 SUPERFAMILY SSF53850 61 250 4.26E-30 T 13-10-2018 Astex_0275 6b4795de26095ef42df94b9edb85aa75 351 Gene3D G3DSA:3.40.190.10 41 263 7.3E-85 T 13-10-2018 Astex_0275 6b4795de26095ef42df94b9edb85aa75 351 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 41 290 7.8E-62 T 13-10-2018 Astex_0275 6b4795de26095ef42df94b9edb85aa75 351 TIGRFAM TIGR01098 3A0109s03R: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein 7 260 1.8E-75 T 13-10-2018 IPR005770 Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein GO:0043190|GO:0055085 Astex_1238 5b51736daa878ce0f13d45a08b41aeb7 368 SMART SM00257 115 159 9.2E-9 T 13-10-2018 IPR018392 LysM domain Astex_1238 5b51736daa878ce0f13d45a08b41aeb7 368 Pfam PF01551 Peptidase family M23 264 352 4.6E-26 T 13-10-2018 IPR016047 Peptidase M23 Astex_1238 5b51736daa878ce0f13d45a08b41aeb7 368 Gene3D G3DSA:3.10.350.10 107 172 2.3E-12 T 13-10-2018 IPR036779 LysM domain superfamily Astex_1238 5b51736daa878ce0f13d45a08b41aeb7 368 Gene3D G3DSA:2.70.70.10 229 367 4.7E-33 T 13-10-2018 IPR011055 Duplicated hybrid motif Astex_1238 5b51736daa878ce0f13d45a08b41aeb7 368 Pfam PF01476 LysM domain 116 159 2.3E-9 T 13-10-2018 IPR018392 LysM domain Astex_1238 5b51736daa878ce0f13d45a08b41aeb7 368 SUPERFAMILY SSF51261 119 367 9.94E-38 T 13-10-2018 IPR011055 Duplicated hybrid motif Astex_2878 929e478a28c4cda8c6778a106bcde3a0 255 Gene3D G3DSA:2.40.40.10 73 165 2.4E-31 T 13-10-2018 IPR036908 RlpA-like domain superfamily Astex_2878 929e478a28c4cda8c6778a106bcde3a0 255 Hamap MF_02071 Endolytic peptidoglycan transglycosylase RlpA [rlpA]. 12 164 22.886 T 13-10-2018 IPR034718 Endolytic peptidoglycan transglycosylase RlpA GO:0016829 Astex_2878 929e478a28c4cda8c6778a106bcde3a0 255 Pfam PF03330 Lytic transglycolase 74 161 2.1E-20 T 13-10-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain Astex_2878 929e478a28c4cda8c6778a106bcde3a0 255 SUPERFAMILY SSF50685 81 163 1.15E-6 T 13-10-2018 IPR036908 RlpA-like domain superfamily Astex_2878 929e478a28c4cda8c6778a106bcde3a0 255 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 75 167 6.7E-33 T 13-10-2018 IPR012997 Rare lipoprotein A Astex_2878 929e478a28c4cda8c6778a106bcde3a0 255 Pfam PF05036 Sporulation related domain 188 251 2.4E-10 T 13-10-2018 IPR007730 Sporulation-like domain GO:0042834 Astex_2878 929e478a28c4cda8c6778a106bcde3a0 255 Gene3D G3DSA:3.30.70.1070 188 253 9.0E-10 T 13-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 Astex_2878 929e478a28c4cda8c6778a106bcde3a0 255 SUPERFAMILY SSF110997 187 251 1.83E-11 T 13-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 Astex_1594 02a2c8338c003b9f1208a2444f51dcb7 275 SUPERFAMILY SSF56655 7 266 6.54E-69 T 13-10-2018 Astex_1594 02a2c8338c003b9f1208a2444f51dcb7 275 Pfam PF00459 Inositol monophosphatase family 8 263 1.7E-46 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Astex_1594 02a2c8338c003b9f1208a2444f51dcb7 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 69 85 5.5E-25 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Astex_1594 02a2c8338c003b9f1208a2444f51dcb7 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 184 205 5.5E-25 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Astex_1594 02a2c8338c003b9f1208a2444f51dcb7 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 89 105 5.5E-25 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Astex_1594 02a2c8338c003b9f1208a2444f51dcb7 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 47 67 5.5E-25 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Astex_1594 02a2c8338c003b9f1208a2444f51dcb7 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 215 239 5.5E-25 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Astex_1594 02a2c8338c003b9f1208a2444f51dcb7 275 Gene3D G3DSA:3.40.190.80 152 265 2.4E-30 T 13-10-2018 Astex_1594 02a2c8338c003b9f1208a2444f51dcb7 275 TIGRFAM TIGR02067 his_9_HisN: histidinol-phosphatase 11 264 5.8E-89 T 13-10-2018 IPR011809 Histidinol-phosphate phosphatase, putative, inositol monophosphatase GO:0004401 KEGG: 00340+3.1.3.15 Astex_1594 02a2c8338c003b9f1208a2444f51dcb7 275 Gene3D G3DSA:3.30.540.10 2 140 2.3E-38 T 13-10-2018 Astex_1594 02a2c8338c003b9f1208a2444f51dcb7 275 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 89 102 - T 13-10-2018 IPR020583 Inositol monophosphatase, metal-binding site Astex_1081 80afec9077e52dbab1f84a3ff4e13adc 90 Pfam PF01722 BolA-like protein 12 89 1.9E-30 T 13-10-2018 IPR002634 BolA protein Astex_1081 80afec9077e52dbab1f84a3ff4e13adc 90 Gene3D G3DSA:3.30.300.90 3 90 3.1E-32 T 13-10-2018 Astex_1081 80afec9077e52dbab1f84a3ff4e13adc 90 SUPERFAMILY SSF82657 3 89 1.44E-27 T 13-10-2018 IPR036065 BolA-like superfamily Astex_1081 80afec9077e52dbab1f84a3ff4e13adc 90 PIRSF PIRSF003113 1 90 2.7E-30 T 13-10-2018 IPR002634 BolA protein Astex_1766 33b88358102862695f62832d4b80193d 334 Gene3D G3DSA:3.10.290.10 19 76 4.5E-10 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 Astex_1766 33b88358102862695f62832d4b80193d 334 Pfam PF00849 RNA pseudouridylate synthase 104 263 1.5E-33 T 13-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 Astex_1766 33b88358102862695f62832d4b80193d 334 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 151 165 - T 13-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Astex_1766 33b88358102862695f62832d4b80193d 334 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 27 331 3.6E-88 T 13-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 Astex_1766 33b88358102862695f62832d4b80193d 334 Gene3D G3DSA:3.30.2350.10 97 333 3.8E-73 T 13-10-2018 Astex_1766 33b88358102862695f62832d4b80193d 334 SUPERFAMILY SSF55120 91 331 3.08E-74 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 Astex_1577 06e85ed3015617245df4f86963d7b5c8 252 Hamap MF_00361 NAD kinase [nadK]. 1 252 20.08 T 13-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 Astex_1577 06e85ed3015617245df4f86963d7b5c8 252 Gene3D G3DSA:3.40.50.10330 16 91 6.8E-39 T 13-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 Astex_1577 06e85ed3015617245df4f86963d7b5c8 252 SUPERFAMILY SSF111331 29 236 1.05E-52 T 13-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily Astex_1577 06e85ed3015617245df4f86963d7b5c8 252 Pfam PF01513 ATP-NAD kinase 30 199 1.1E-17 T 13-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 Astex_1577 06e85ed3015617245df4f86963d7b5c8 252 Gene3D G3DSA:2.60.200.30 92 229 6.8E-39 T 13-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 Astex_3112 e5e77bfd6a5348183a8db76e7ac653c5 1162 Pfam PF14559 Tetratricopeptide repeat 167 220 3.9E-7 T 13-10-2018 Astex_3112 e5e77bfd6a5348183a8db76e7ac653c5 1162 Gene3D G3DSA:1.25.40.10 51 324 5.7E-40 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_3112 e5e77bfd6a5348183a8db76e7ac653c5 1162 SUPERFAMILY SSF53756 892 1148 1.02E-15 T 13-10-2018 Astex_3112 e5e77bfd6a5348183a8db76e7ac653c5 1162 SUPERFAMILY SSF48452 665 831 2.82E-25 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_3112 e5e77bfd6a5348183a8db76e7ac653c5 1162 SMART SM00028 668 701 0.003 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Astex_3112 e5e77bfd6a5348183a8db76e7ac653c5 1162 SMART SM00028 187 220 44.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Astex_3112 e5e77bfd6a5348183a8db76e7ac653c5 1162 SMART SM00028 770 803 0.81 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Astex_3112 e5e77bfd6a5348183a8db76e7ac653c5 1162 SMART SM00028 255 288 1.2 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Astex_3112 e5e77bfd6a5348183a8db76e7ac653c5 1162 SMART SM00028 119 152 0.032 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Astex_3112 e5e77bfd6a5348183a8db76e7ac653c5 1162 SMART SM00028 221 254 4.5 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Astex_3112 e5e77bfd6a5348183a8db76e7ac653c5 1162 SMART SM00028 153 186 15.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Astex_3112 e5e77bfd6a5348183a8db76e7ac653c5 1162 SMART SM00028 702 735 78.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Astex_3112 e5e77bfd6a5348183a8db76e7ac653c5 1162 Pfam PF13181 Tetratricopeptide repeat 257 283 0.04 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Astex_3112 e5e77bfd6a5348183a8db76e7ac653c5 1162 SUPERFAMILY SSF48452 85 455 5.31E-32 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_3112 e5e77bfd6a5348183a8db76e7ac653c5 1162 SUPERFAMILY SSF53756 345 604 2.51E-14 T 13-10-2018 Astex_3112 e5e77bfd6a5348183a8db76e7ac653c5 1162 Pfam PF13432 Tetratricopeptide repeat 743 798 3.2E-6 T 13-10-2018 Astex_3112 e5e77bfd6a5348183a8db76e7ac653c5 1162 Pfam PF13432 Tetratricopeptide repeat 648 701 2.6E-5 T 13-10-2018 Astex_3112 e5e77bfd6a5348183a8db76e7ac653c5 1162 Gene3D G3DSA:1.25.40.10 631 866 8.1E-31 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_3453 cd03cb1c6f237440f390c0e4b7d1d24a 304 Pfam PF00589 Phage integrase family 110 285 1.2E-44 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 Astex_3453 cd03cb1c6f237440f390c0e4b7d1d24a 304 Gene3D G3DSA:1.10.443.10 109 293 3.7E-57 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 Astex_3453 cd03cb1c6f237440f390c0e4b7d1d24a 304 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 4 299 51.959 T 13-10-2018 IPR023009 Tyrosine recombinase XerC/XerD Astex_3453 cd03cb1c6f237440f390c0e4b7d1d24a 304 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 6 88 4.8E-18 T 13-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 Astex_3453 cd03cb1c6f237440f390c0e4b7d1d24a 304 SUPERFAMILY SSF56349 9 292 3.83E-56 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 Astex_3453 cd03cb1c6f237440f390c0e4b7d1d24a 304 Gene3D G3DSA:1.10.150.130 4 97 9.8E-18 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal Astex_0057 995ed7ce92c1e82a2cdc190b67729c54 389 Pfam PF00684 DnaJ central domain 151 211 6.9E-13 T 13-10-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 Astex_0057 995ed7ce92c1e82a2cdc190b67729c54 389 Gene3D G3DSA:1.10.287.110 1 116 2.1E-34 T 13-10-2018 IPR036869 Chaperone J-domain superfamily Astex_0057 995ed7ce92c1e82a2cdc190b67729c54 389 Pfam PF00226 DnaJ domain 4 66 1.9E-25 T 13-10-2018 IPR001623 DnaJ domain Astex_0057 995ed7ce92c1e82a2cdc190b67729c54 389 SUPERFAMILY SSF49493 263 356 2.49E-20 T 13-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 Astex_0057 995ed7ce92c1e82a2cdc190b67729c54 389 Gene3D G3DSA:2.60.260.20 258 378 6.4E-29 T 13-10-2018 Astex_0057 995ed7ce92c1e82a2cdc190b67729c54 389 SUPERFAMILY SSF49493 118 265 2.62E-19 T 13-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 Astex_0057 995ed7ce92c1e82a2cdc190b67729c54 389 PRINTS PR00625 DnaJ domain signature 6 24 4.9E-28 T 13-10-2018 IPR001623 DnaJ domain Astex_0057 995ed7ce92c1e82a2cdc190b67729c54 389 PRINTS PR00625 DnaJ domain signature 24 39 4.9E-28 T 13-10-2018 IPR001623 DnaJ domain Astex_0057 995ed7ce92c1e82a2cdc190b67729c54 389 PRINTS PR00625 DnaJ domain signature 61 80 4.9E-28 T 13-10-2018 IPR001623 DnaJ domain Astex_0057 995ed7ce92c1e82a2cdc190b67729c54 389 PRINTS PR00625 DnaJ domain signature 41 61 4.9E-28 T 13-10-2018 IPR001623 DnaJ domain Astex_0057 995ed7ce92c1e82a2cdc190b67729c54 389 Gene3D G3DSA:2.60.260.20 121 253 5.2E-36 T 13-10-2018 Astex_0057 995ed7ce92c1e82a2cdc190b67729c54 389 ProSitePatterns PS00636 Nt-dnaJ domain signature. 46 65 - T 13-10-2018 IPR018253 DnaJ domain, conserved site Astex_0057 995ed7ce92c1e82a2cdc190b67729c54 389 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 1 381 40.042 T 13-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 Astex_0057 995ed7ce92c1e82a2cdc190b67729c54 389 SUPERFAMILY SSF57938 138 214 5.89E-21 T 13-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily Astex_0057 995ed7ce92c1e82a2cdc190b67729c54 389 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 4 361 4.5E-127 T 13-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 Astex_0057 995ed7ce92c1e82a2cdc190b67729c54 389 Pfam PF01556 DnaJ C terminal domain 124 345 4.3E-40 T 13-10-2018 IPR002939 Chaperone DnaJ, C-terminal Astex_0057 995ed7ce92c1e82a2cdc190b67729c54 389 Gene3D G3DSA:2.10.230.10 151 211 5.2E-36 T 13-10-2018 Astex_0057 995ed7ce92c1e82a2cdc190b67729c54 389 SMART SM00271 3 61 3.2E-29 T 13-10-2018 IPR001623 DnaJ domain Astex_0057 995ed7ce92c1e82a2cdc190b67729c54 389 SUPERFAMILY SSF46565 3 113 1.14E-32 T 13-10-2018 IPR036869 Chaperone J-domain superfamily Astex_2158 43604edcfa5bf112d48b966c25e88bdb 1301 Gene3D G3DSA:2.60.390.10 871 948 3.0E-6 T 13-10-2018 IPR036833 Beta-galactosidase, domain 3 superfamily KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_2158 43604edcfa5bf112d48b966c25e88bdb 1301 SUPERFAMILY SSF51445 338 687 2.83E-88 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_2158 43604edcfa5bf112d48b966c25e88bdb 1301 SUPERFAMILY SSF117100 868 949 7.06E-13 T 13-10-2018 IPR036833 Beta-galactosidase, domain 3 superfamily KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_2158 43604edcfa5bf112d48b966c25e88bdb 1301 SUPERFAMILY SSF49785 953 1141 1.7E-27 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_2158 43604edcfa5bf112d48b966c25e88bdb 1301 PRINTS PR00742 Glycosyl hydrolase family 35 signature 641 656 1.7E-24 T 13-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_2158 43604edcfa5bf112d48b966c25e88bdb 1301 PRINTS PR00742 Glycosyl hydrolase family 35 signature 372 390 1.7E-24 T 13-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_2158 43604edcfa5bf112d48b966c25e88bdb 1301 PRINTS PR00742 Glycosyl hydrolase family 35 signature 1045 1061 1.7E-24 T 13-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_2158 43604edcfa5bf112d48b966c25e88bdb 1301 PRINTS PR00742 Glycosyl hydrolase family 35 signature 482 497 1.7E-24 T 13-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_2158 43604edcfa5bf112d48b966c25e88bdb 1301 PRINTS PR00742 Glycosyl hydrolase family 35 signature 427 446 1.7E-24 T 13-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_2158 43604edcfa5bf112d48b966c25e88bdb 1301 PRINTS PR00742 Glycosyl hydrolase family 35 signature 660 676 1.7E-24 T 13-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_2158 43604edcfa5bf112d48b966c25e88bdb 1301 PRINTS PR00742 Glycosyl hydrolase family 35 signature 350 367 1.7E-24 T 13-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_2158 43604edcfa5bf112d48b966c25e88bdb 1301 Gene3D G3DSA:2.60.120.260 971 1155 4.0E-97 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_2158 43604edcfa5bf112d48b966c25e88bdb 1301 Pfam PF13364 Beta-galactosidase jelly roll domain 1156 1267 6.5E-27 T 13-10-2018 IPR025300 Beta-galactosidase jelly roll domain KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024096|Reactome: R-HSA-2206308|Reactome: R-HSA-4085001|Reactome: R-HSA-6798695 Astex_2158 43604edcfa5bf112d48b966c25e88bdb 1301 Pfam PF13364 Beta-galactosidase jelly roll domain 978 1097 2.2E-22 T 13-10-2018 IPR025300 Beta-galactosidase jelly roll domain KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024096|Reactome: R-HSA-2206308|Reactome: R-HSA-4085001|Reactome: R-HSA-6798695 Astex_2158 43604edcfa5bf112d48b966c25e88bdb 1301 Pfam PF13363 Beta-galactosidase, domain 3 887 943 1.5E-11 T 13-10-2018 IPR025972 Beta-galactosidase, domain 3 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_2158 43604edcfa5bf112d48b966c25e88bdb 1301 Pfam PF10435 Beta-galactosidase, domain 2 706 875 1.9E-21 T 13-10-2018 IPR018954 Beta-galactosidase, domain 2 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_2158 43604edcfa5bf112d48b966c25e88bdb 1301 SUPERFAMILY SSF49785 1144 1288 6.27E-32 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_2158 43604edcfa5bf112d48b966c25e88bdb 1301 Gene3D G3DSA:3.20.20.80 334 696 4.4E-131 T 13-10-2018 Astex_2158 43604edcfa5bf112d48b966c25e88bdb 1301 Gene3D G3DSA:2.102.20.10 702 870 2.1E-22 T 13-10-2018 IPR037110 Beta-galactosidase, domain 2 superfamily KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_2158 43604edcfa5bf112d48b966c25e88bdb 1301 Pfam PF04616 Glycosyl hydrolases family 43 103 272 1.5E-11 T 13-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 Astex_2158 43604edcfa5bf112d48b966c25e88bdb 1301 SMART SM01029 696 875 6.5E-35 T 13-10-2018 IPR018954 Beta-galactosidase, domain 2 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_2158 43604edcfa5bf112d48b966c25e88bdb 1301 SUPERFAMILY SSF51011 705 862 2.01E-23 T 13-10-2018 Astex_2158 43604edcfa5bf112d48b966c25e88bdb 1301 Gene3D G3DSA:2.115.10.20 92 281 1.3E-16 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Astex_2158 43604edcfa5bf112d48b966c25e88bdb 1301 Pfam PF01301 Glycosyl hydrolases family 35 346 688 4.5E-89 T 13-10-2018 IPR031330 Glycoside hydrolase 35, catalytic domain KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_2158 43604edcfa5bf112d48b966c25e88bdb 1301 Gene3D G3DSA:2.60.120.260 955 1287 4.0E-97 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_2158 43604edcfa5bf112d48b966c25e88bdb 1301 SUPERFAMILY SSF75005 103 300 4.06E-22 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Astex_3483 efd050abb6347ec026b8eb9af0770ffb 216 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 43 123 1.3E-26 T 13-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 Astex_3483 efd050abb6347ec026b8eb9af0770ffb 216 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 186 199 - T 13-10-2018 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 Astex_3483 efd050abb6347ec026b8eb9af0770ffb 216 PIRSF PIRSF000190 6 216 2.6E-67 T 13-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 Astex_3483 efd050abb6347ec026b8eb9af0770ffb 216 Gene3D G3DSA:2.30.110.10 10 216 6.0E-76 T 13-10-2018 IPR012349 FMN-binding split barrel GO:0048037 Astex_3483 efd050abb6347ec026b8eb9af0770ffb 216 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 12 216 38.076 T 13-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 Astex_3483 efd050abb6347ec026b8eb9af0770ffb 216 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 176 216 2.8E-16 T 13-10-2018 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 Astex_3483 efd050abb6347ec026b8eb9af0770ffb 216 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 18 216 6.4E-70 T 13-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 Astex_3483 efd050abb6347ec026b8eb9af0770ffb 216 SUPERFAMILY SSF50475 27 216 1.12E-61 T 13-10-2018 Astex_0535 dec1df722db72e63a6877e1647a9acf5 308 Gene3D G3DSA:1.20.120.330 165 308 2.2E-47 T 13-10-2018 Astex_0535 dec1df722db72e63a6877e1647a9acf5 308 Pfam PF01909 Nucleotidyltransferase domain 44 101 9.0E-6 T 13-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 Astex_0535 dec1df722db72e63a6877e1647a9acf5 308 Gene3D G3DSA:3.30.460.10 23 151 6.0E-15 T 13-10-2018 Astex_0535 dec1df722db72e63a6877e1647a9acf5 308 SUPERFAMILY SSF81593 180 280 3.26E-9 T 13-10-2018 Astex_0535 dec1df722db72e63a6877e1647a9acf5 308 SUPERFAMILY SSF81301 34 156 3.97E-12 T 13-10-2018 Astex_0535 dec1df722db72e63a6877e1647a9acf5 308 Pfam PF05168 HEPN domain 179 285 6.1E-11 T 13-10-2018 IPR007842 HEPN domain Astex_0535 dec1df722db72e63a6877e1647a9acf5 308 SMART SM00748 182 302 5.0E-8 T 13-10-2018 IPR007842 HEPN domain Astex_0940 733b210562c67c443227f6e42ff9dcad 692 SMART SM00889 480 598 3.0E-62 T 13-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 Astex_0940 733b210562c67c443227f6e42ff9dcad 692 Pfam PF03764 Elongation factor G, domain IV 479 596 1.9E-41 T 13-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 Astex_0940 733b210562c67c443227f6e42ff9dcad 692 Gene3D G3DSA:3.30.70.240 604 674 1.5E-83 T 13-10-2018 Astex_0940 733b210562c67c443227f6e42ff9dcad 692 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.8E-16 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Astex_0940 733b210562c67c443227f6e42ff9dcad 692 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.8E-16 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Astex_0940 733b210562c67c443227f6e42ff9dcad 692 PRINTS PR00315 GTP-binding elongation factor signature 130 139 1.8E-16 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Astex_0940 733b210562c67c443227f6e42ff9dcad 692 PRINTS PR00315 GTP-binding elongation factor signature 12 25 1.8E-16 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Astex_0940 733b210562c67c443227f6e42ff9dcad 692 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.8E-16 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Astex_0940 733b210562c67c443227f6e42ff9dcad 692 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 180 2.0E-38 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Astex_0940 733b210562c67c443227f6e42ff9dcad 692 SUPERFAMILY SSF52540 6 281 3.37E-109 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0940 733b210562c67c443227f6e42ff9dcad 692 Pfam PF00009 Elongation factor Tu GTP binding domain 9 281 2.5E-71 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Astex_0940 733b210562c67c443227f6e42ff9dcad 692 Gene3D G3DSA:3.40.50.300 1 286 5.0E-117 T 13-10-2018 Astex_0940 733b210562c67c443227f6e42ff9dcad 692 SUPERFAMILY SSF50447 264 392 7.07E-35 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Astex_0940 733b210562c67c443227f6e42ff9dcad 692 Pfam PF03144 Elongation factor Tu domain 2 323 390 9.3E-16 T 13-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 Astex_0940 733b210562c67c443227f6e42ff9dcad 692 Pfam PF00679 Elongation factor G C-terminus 601 686 6.3E-28 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like Astex_0940 733b210562c67c443227f6e42ff9dcad 692 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 690 0.0 T 13-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 Astex_0940 733b210562c67c443227f6e42ff9dcad 692 Gene3D G3DSA:2.40.30.10 289 405 6.3E-43 T 13-10-2018 Astex_0940 733b210562c67c443227f6e42ff9dcad 692 Gene3D G3DSA:3.30.230.10 484 687 1.5E-83 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Astex_0940 733b210562c67c443227f6e42ff9dcad 692 SMART SM00838 600 687 2.5E-49 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like Astex_0940 733b210562c67c443227f6e42ff9dcad 692 Pfam PF14492 Elongation Factor G, domain II 404 477 5.1E-30 T 13-10-2018 Astex_0940 733b210562c67c443227f6e42ff9dcad 692 SUPERFAMILY SSF54980 404 481 8.27E-22 T 13-10-2018 IPR035647 EF-G domain III/V-like Astex_0940 733b210562c67c443227f6e42ff9dcad 692 SUPERFAMILY SSF54211 479 599 1.06E-39 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Astex_0940 733b210562c67c443227f6e42ff9dcad 692 Hamap MF_00054_B Elongation factor G [fusA]. 6 691 109.201 T 13-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 Astex_0940 733b210562c67c443227f6e42ff9dcad 692 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site Astex_0940 733b210562c67c443227f6e42ff9dcad 692 Gene3D G3DSA:3.30.70.870 406 483 5.7E-29 T 13-10-2018 Astex_0940 733b210562c67c443227f6e42ff9dcad 692 SUPERFAMILY SSF54980 603 690 2.11E-29 T 13-10-2018 IPR035647 EF-G domain III/V-like Astex_1141 25257cfaffef6f968c16d654543247ed 179 PRINTS PR00162 Rieske 2Fe-2S subunit signature 151 163 8.2E-17 T 13-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 Astex_1141 25257cfaffef6f968c16d654543247ed 179 PRINTS PR00162 Rieske 2Fe-2S subunit signature 139 151 8.2E-17 T 13-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 Astex_1141 25257cfaffef6f968c16d654543247ed 179 PRINTS PR00162 Rieske 2Fe-2S subunit signature 117 128 8.2E-17 T 13-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 Astex_1141 25257cfaffef6f968c16d654543247ed 179 Pfam PF10399 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal 8 46 3.5E-15 T 13-10-2018 IPR019470 Ubiquitinol-cytochrome C reductase, Fe-S subunit, TAT signal GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 Astex_1141 25257cfaffef6f968c16d654543247ed 179 SUPERFAMILY SSF50022 38 174 3.4E-39 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 Astex_1141 25257cfaffef6f968c16d654543247ed 179 Pfam PF00355 Rieske [2Fe-2S] domain 109 165 3.1E-12 T 13-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Astex_1141 25257cfaffef6f968c16d654543247ed 179 TIGRFAM TIGR01416 Rieske_proteo: ubiquinol-cytochrome c reductase, iron-sulfur subunit 15 179 3.9E-67 T 13-10-2018 IPR006317 Ubiquinol-cytochrome c reductase, iron-sulphur subunit GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 Astex_1141 25257cfaffef6f968c16d654543247ed 179 Gene3D G3DSA:1.20.5.510 6 46 2.7E-11 T 13-10-2018 Astex_1141 25257cfaffef6f968c16d654543247ed 179 Gene3D G3DSA:2.102.10.10 47 179 4.4E-49 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 Astex_3005 7271ece01e1c3fdaff53f0dc5e5b19de 146 Gene3D G3DSA:3.40.50.9100 1 146 8.5E-60 T 13-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 Astex_3005 7271ece01e1c3fdaff53f0dc5e5b19de 146 ProSitePatterns PS01029 Dehydroquinase class II signature. 8 25 - T 13-10-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 Astex_3005 7271ece01e1c3fdaff53f0dc5e5b19de 146 Pfam PF01220 Dehydroquinase class II 5 140 1.4E-55 T 13-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 Astex_3005 7271ece01e1c3fdaff53f0dc5e5b19de 146 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 18 140 8.0E-46 T 13-10-2018 Astex_3005 7271ece01e1c3fdaff53f0dc5e5b19de 146 PIRSF PIRSF001399 1 146 1.6E-58 T 13-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 Astex_3005 7271ece01e1c3fdaff53f0dc5e5b19de 146 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 146 65.712 T 13-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 Astex_3005 7271ece01e1c3fdaff53f0dc5e5b19de 146 SUPERFAMILY SSF52304 4 145 2.22E-57 T 13-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 Astex_3005 7271ece01e1c3fdaff53f0dc5e5b19de 146 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 5 142 3.4E-53 T 13-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 Astex_3528 a67b01145ef62d1720e4c2ef092b8a70 390 Gene3D G3DSA:1.25.40.80 5 89 1.4E-13 T 13-10-2018 Astex_3528 a67b01145ef62d1720e4c2ef092b8a70 390 Gene3D G3DSA:1.10.579.10 103 217 1.2E-26 T 13-10-2018 Astex_3528 a67b01145ef62d1720e4c2ef092b8a70 390 Pfam PF03441 FAD binding domain of DNA photolyase 74 193 1.4E-20 T 13-10-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-400253 Astex_3528 a67b01145ef62d1720e4c2ef092b8a70 390 SUPERFAMILY SSF48173 7 201 4.97E-47 T 13-10-2018 IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily Reactome: R-HSA-400253 Astex_2818 a7799395c8042cd547e90266911af110 242 Pfam PF03099 Biotin/lipoate A/B protein ligase family 9 132 2.8E-12 T 13-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 Astex_2818 a7799395c8042cd547e90266911af110 242 SUPERFAMILY SSF55681 4 189 8.62E-44 T 13-10-2018 Astex_2818 a7799395c8042cd547e90266911af110 242 Pfam PF02237 Biotin protein ligase C terminal domain 204 238 1.1E-6 T 13-10-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Astex_2818 a7799395c8042cd547e90266911af110 242 Gene3D G3DSA:3.30.930.10 1 191 2.0E-47 T 13-10-2018 Astex_2818 a7799395c8042cd547e90266911af110 242 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 4 238 8.8E-37 T 13-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Astex_2818 a7799395c8042cd547e90266911af110 242 Gene3D G3DSA:2.30.30.100 199 239 2.0E-6 T 13-10-2018 Astex_2818 a7799395c8042cd547e90266911af110 242 SUPERFAMILY SSF50037 204 239 1.83E-5 T 13-10-2018 IPR008988 Transcriptional repressor, C-terminal Astex_1813 6411ee3725053a95bfff01b00795ff0a 169 SUPERFAMILY SSF55729 5 163 3.6E-25 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Astex_1813 6411ee3725053a95bfff01b00795ff0a 169 Gene3D G3DSA:3.40.630.30 2 168 1.8E-25 T 13-10-2018 Astex_1813 6411ee3725053a95bfff01b00795ff0a 169 Pfam PF13673 Acetyltransferase (GNAT) domain 49 157 4.2E-12 T 13-10-2018 IPR000182 GNAT domain Astex_0739 32b2800187795148f73cadc60658c15e 321 SMART SM00748 195 315 4.4E-9 T 13-10-2018 IPR007842 HEPN domain Astex_0739 32b2800187795148f73cadc60658c15e 321 Gene3D G3DSA:1.20.120.330 178 321 2.0E-46 T 13-10-2018 Astex_0739 32b2800187795148f73cadc60658c15e 321 Pfam PF05168 HEPN domain 191 298 6.2E-11 T 13-10-2018 IPR007842 HEPN domain Astex_0739 32b2800187795148f73cadc60658c15e 321 SUPERFAMILY SSF81301 47 169 4.44E-12 T 13-10-2018 Astex_0739 32b2800187795148f73cadc60658c15e 321 SUPERFAMILY SSF81593 193 298 2.43E-7 T 13-10-2018 Astex_0739 32b2800187795148f73cadc60658c15e 321 Pfam PF01909 Nucleotidyltransferase domain 57 113 1.1E-5 T 13-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 Astex_0739 32b2800187795148f73cadc60658c15e 321 Gene3D G3DSA:3.30.460.10 36 164 9.1E-15 T 13-10-2018 Astex_3364 5ce37cef5a4525897180116bf7a1c3c4 350 Gene3D G3DSA:3.40.50.10490 11 201 3.3E-43 T 13-10-2018 Astex_3364 5ce37cef5a4525897180116bf7a1c3c4 350 Gene3D G3DSA:3.40.50.10490 207 335 4.7E-40 T 13-10-2018 Astex_3364 5ce37cef5a4525897180116bf7a1c3c4 350 Pfam PF01380 SIS domain 210 292 3.7E-12 T 13-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 Astex_3364 5ce37cef5a4525897180116bf7a1c3c4 350 Pfam PF01380 SIS domain 52 175 3.0E-15 T 13-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 Astex_3364 5ce37cef5a4525897180116bf7a1c3c4 350 SUPERFAMILY SSF53697 19 348 8.06E-67 T 13-10-2018 Astex_3627 68b349a370ad6392adfa8f91147fdabf 335 SUPERFAMILY SSF51735 4 324 3.66E-47 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_3627 68b349a370ad6392adfa8f91147fdabf 335 Gene3D G3DSA:3.40.50.720 1 295 1.9E-70 T 13-10-2018 Astex_3627 68b349a370ad6392adfa8f91147fdabf 335 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 237 1.9E-14 T 13-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 Astex_1515 349dc9b17b9f4337b96baa37a492f607 230 Gene3D G3DSA:3.40.50.1360 9 215 6.7E-70 T 13-10-2018 Astex_1515 349dc9b17b9f4337b96baa37a492f607 230 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 6 225 2.0E-71 T 13-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 Astex_1515 349dc9b17b9f4337b96baa37a492f607 230 SUPERFAMILY SSF75445 128 211 2.49E-17 T 13-10-2018 Astex_1515 349dc9b17b9f4337b96baa37a492f607 230 SUPERFAMILY SSF100950 5 147 5.02E-39 T 13-10-2018 IPR037171 NagB/RpiA transferase-like Astex_1515 349dc9b17b9f4337b96baa37a492f607 230 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 51 224 5.7E-55 T 13-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 Astex_1515 349dc9b17b9f4337b96baa37a492f607 230 Gene3D G3DSA:3.30.70.260 122 199 6.7E-70 T 13-10-2018 Astex_1515 349dc9b17b9f4337b96baa37a492f607 230 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 3 228 29.852 T 13-10-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 Astex_1921 cb608c1be8220a20b0bee49220d06123 1098 Pfam PF02142 MGS-like domain 984 1069 2.6E-17 T 13-10-2018 IPR011607 Methylglyoxal synthase-like domain Astex_1921 cb608c1be8220a20b0bee49220d06123 1098 SUPERFAMILY SSF52440 569 691 1.14E-43 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily Astex_1921 cb608c1be8220a20b0bee49220d06123 1098 Gene3D G3DSA:3.30.470.20 681 962 2.6E-104 T 13-10-2018 Astex_1921 cb608c1be8220a20b0bee49220d06123 1098 Gene3D G3DSA:3.40.50.1380 964 1098 8.8E-37 T 13-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily Astex_1921 cb608c1be8220a20b0bee49220d06123 1098 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 1.9E-63 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Astex_1921 cb608c1be8220a20b0bee49220d06123 1098 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 1.9E-63 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Astex_1921 cb608c1be8220a20b0bee49220d06123 1098 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 205 224 1.9E-63 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Astex_1921 cb608c1be8220a20b0bee49220d06123 1098 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 169 181 1.9E-63 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Astex_1921 cb608c1be8220a20b0bee49220d06123 1098 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 240 257 1.9E-63 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Astex_1921 cb608c1be8220a20b0bee49220d06123 1098 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 298 327 1.9E-63 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Astex_1921 cb608c1be8220a20b0bee49220d06123 1098 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 380 398 1.9E-63 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Astex_1921 cb608c1be8220a20b0bee49220d06123 1098 Gene3D G3DSA:1.10.1030.10 409 556 2.4E-42 T 13-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Astex_1921 cb608c1be8220a20b0bee49220d06123 1098 SMART SM00851 983 1069 1.1E-26 T 13-10-2018 IPR011607 Methylglyoxal synthase-like domain Astex_1921 cb608c1be8220a20b0bee49220d06123 1098 Gene3D G3DSA:3.30.470.20 119 403 6.3E-125 T 13-10-2018 Astex_1921 cb608c1be8220a20b0bee49220d06123 1098 SMART SM01096 430 552 2.4E-67 T 13-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Astex_1921 cb608c1be8220a20b0bee49220d06123 1098 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 858 865 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Astex_1921 cb608c1be8220a20b0bee49220d06123 1098 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 298 305 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Astex_1921 cb608c1be8220a20b0bee49220d06123 1098 Gene3D G3DSA:3.40.50.20 566 678 1.5E-44 T 13-10-2018 Astex_1921 cb608c1be8220a20b0bee49220d06123 1098 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1089 12.883 T 13-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Astex_1921 cb608c1be8220a20b0bee49220d06123 1098 SUPERFAMILY SSF56059 128 401 1.94E-104 T 13-10-2018 Astex_1921 cb608c1be8220a20b0bee49220d06123 1098 SUPERFAMILY SSF52335 963 1097 1.3E-37 T 13-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily Astex_1921 cb608c1be8220a20b0bee49220d06123 1098 Gene3D G3DSA:3.40.50.20 1 116 9.7E-51 T 13-10-2018 Astex_1921 cb608c1be8220a20b0bee49220d06123 1098 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 725 739 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Astex_1921 cb608c1be8220a20b0bee49220d06123 1098 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 433 552 1.9E-39 T 13-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Astex_1921 cb608c1be8220a20b0bee49220d06123 1098 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1080 0.0 T 13-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Astex_1921 cb608c1be8220a20b0bee49220d06123 1098 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 689 894 1.6E-35 T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Astex_1921 cb608c1be8220a20b0bee49220d06123 1098 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 335 1.2E-68 T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Astex_1921 cb608c1be8220a20b0bee49220d06123 1098 SUPERFAMILY SSF48108 396 554 4.05E-46 T 13-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Astex_1921 cb608c1be8220a20b0bee49220d06123 1098 SUPERFAMILY SSF52440 1 127 1.34E-49 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily Astex_1921 cb608c1be8220a20b0bee49220d06123 1098 SUPERFAMILY SSF56059 689 940 5.3E-93 T 13-10-2018 Astex_2405 f6e7ed39d1c8091246d930414c9bd172 413 Gene3D G3DSA:1.10.10.10 6 94 1.2E-19 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_2405 f6e7ed39d1c8091246d930414c9bd172 413 SUPERFAMILY SSF46785 103 214 1.25E-18 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_2405 f6e7ed39d1c8091246d930414c9bd172 413 SUPERFAMILY SSF46785 3 93 4.08E-16 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_2405 f6e7ed39d1c8091246d930414c9bd172 413 Gene3D G3DSA:3.40.190.10 269 368 1.2E-43 T 13-10-2018 Astex_2405 f6e7ed39d1c8091246d930414c9bd172 413 Pfam PF03466 LysR substrate binding domain 192 395 1.4E-29 T 13-10-2018 IPR005119 LysR, substrate-binding Astex_2405 f6e7ed39d1c8091246d930414c9bd172 413 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 68 1.9E-15 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_2405 f6e7ed39d1c8091246d930414c9bd172 413 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 108 165 2.2E-14 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_2405 f6e7ed39d1c8091246d930414c9bd172 413 SUPERFAMILY SSF53850 193 399 5.43E-34 T 13-10-2018 Astex_2405 f6e7ed39d1c8091246d930414c9bd172 413 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 132 142 9.6E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_2405 f6e7ed39d1c8091246d930414c9bd172 413 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 142 153 9.6E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_2405 f6e7ed39d1c8091246d930414c9bd172 413 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 121 132 9.6E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_2405 f6e7ed39d1c8091246d930414c9bd172 413 Gene3D G3DSA:3.40.190.10 195 382 1.2E-43 T 13-10-2018 Astex_2405 f6e7ed39d1c8091246d930414c9bd172 413 Gene3D G3DSA:1.10.10.10 104 191 8.2E-18 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_3526 43491321e50bef40eb4f94c72172b5fb 472 Gene3D G3DSA:3.40.720.10 26 472 1.3E-151 T 13-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 Astex_3526 43491321e50bef40eb4f94c72172b5fb 472 SMART SM00098 44 472 1.5E-131 T 13-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 Astex_3526 43491321e50bef40eb4f94c72172b5fb 472 PRINTS PR00113 Alkaline phosphatase signature 287 316 1.7E-40 T 13-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 Astex_3526 43491321e50bef40eb4f94c72172b5fb 472 PRINTS PR00113 Alkaline phosphatase signature 99 114 1.7E-40 T 13-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 Astex_3526 43491321e50bef40eb4f94c72172b5fb 472 PRINTS PR00113 Alkaline phosphatase signature 208 218 1.7E-40 T 13-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 Astex_3526 43491321e50bef40eb4f94c72172b5fb 472 PRINTS PR00113 Alkaline phosphatase signature 43 63 1.7E-40 T 13-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 Astex_3526 43491321e50bef40eb4f94c72172b5fb 472 PRINTS PR00113 Alkaline phosphatase signature 146 166 1.7E-40 T 13-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 Astex_3526 43491321e50bef40eb4f94c72172b5fb 472 Pfam PF00245 Alkaline phosphatase 43 470 4.5E-115 T 13-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 Astex_3526 43491321e50bef40eb4f94c72172b5fb 472 SUPERFAMILY SSF53649 32 470 2.43E-131 T 13-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 Astex_1920 05d950f7f755bea4c1e1f490565e09e8 390 SMART SM01097 8 142 2.2E-76 T 13-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Astex_1920 05d950f7f755bea4c1e1f490565e09e8 390 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 8 387 45.368 T 13-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Astex_1920 05d950f7f755bea4c1e1f490565e09e8 390 PRINTS PR00097 Anthranilate synthase component II signature 273 284 3.7E-6 T 13-10-2018 Astex_1920 05d950f7f755bea4c1e1f490565e09e8 390 PRINTS PR00097 Anthranilate synthase component II signature 244 253 3.7E-6 T 13-10-2018 Astex_1920 05d950f7f755bea4c1e1f490565e09e8 390 PRINTS PR00097 Anthranilate synthase component II signature 358 371 3.7E-6 T 13-10-2018 Astex_1920 05d950f7f755bea4c1e1f490565e09e8 390 SUPERFAMILY SSF52317 194 385 1.68E-60 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Astex_1920 05d950f7f755bea4c1e1f490565e09e8 390 PRINTS PR00096 Glutamine amidotransferase superfamily signature 358 371 2.3E-11 T 13-10-2018 Astex_1920 05d950f7f755bea4c1e1f490565e09e8 390 PRINTS PR00096 Glutamine amidotransferase superfamily signature 273 284 2.3E-11 T 13-10-2018 Astex_1920 05d950f7f755bea4c1e1f490565e09e8 390 PRINTS PR00096 Glutamine amidotransferase superfamily signature 244 253 2.3E-11 T 13-10-2018 Astex_1920 05d950f7f755bea4c1e1f490565e09e8 390 Pfam PF00117 Glutamine amidotransferase class-I 203 380 3.6E-45 T 13-10-2018 IPR017926 Glutamine amidotransferase Astex_1920 05d950f7f755bea4c1e1f490565e09e8 390 Gene3D G3DSA:3.50.30.20 8 159 3.6E-50 T 13-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Astex_1920 05d950f7f755bea4c1e1f490565e09e8 390 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 11 384 5.5E-127 T 13-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Astex_1920 05d950f7f755bea4c1e1f490565e09e8 390 SUPERFAMILY SSF52021 9 158 1.29E-51 T 13-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Astex_1920 05d950f7f755bea4c1e1f490565e09e8 390 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 10 141 3.2E-46 T 13-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Astex_1920 05d950f7f755bea4c1e1f490565e09e8 390 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 315 326 3.9E-37 T 13-10-2018 Astex_1920 05d950f7f755bea4c1e1f490565e09e8 390 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 241 255 3.9E-37 T 13-10-2018 Astex_1920 05d950f7f755bea4c1e1f490565e09e8 390 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 273 289 3.9E-37 T 13-10-2018 Astex_1920 05d950f7f755bea4c1e1f490565e09e8 390 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 202 216 3.9E-37 T 13-10-2018 Astex_1920 05d950f7f755bea4c1e1f490565e09e8 390 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 290 307 3.9E-37 T 13-10-2018 Astex_1920 05d950f7f755bea4c1e1f490565e09e8 390 Gene3D G3DSA:3.40.50.880 163 386 1.6E-67 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Astex_1275 f6ff3b542a1bdf34f5f06d4f1486f0f1 335 Gene3D G3DSA:2.115.10.20 28 334 1.3E-29 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Astex_1275 f6ff3b542a1bdf34f5f06d4f1486f0f1 335 Pfam PF04616 Glycosyl hydrolases family 43 36 318 3.0E-11 T 13-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 Astex_1275 f6ff3b542a1bdf34f5f06d4f1486f0f1 335 SUPERFAMILY SSF75005 33 320 1.12E-38 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Astex_0018 72d544d5bdc936823e9ab3dd233ce6c2 577 Gene3D G3DSA:1.50.10.100 69 316 2.9E-23 T 13-10-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 Astex_0018 72d544d5bdc936823e9ab3dd233ce6c2 577 Pfam PF07940 Heparinase II/III-like protein 327 570 6.8E-32 T 13-10-2018 IPR012480 Heparinase II/III-like GO:0016829 Astex_0867 338a6fc193434baa0d7a8782895c65fd 315 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 123 304 2.9E-8 T 13-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase Astex_0867 338a6fc193434baa0d7a8782895c65fd 315 SUPERFAMILY SSF56219 105 311 3.93E-22 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily Astex_0867 338a6fc193434baa0d7a8782895c65fd 315 Gene3D G3DSA:3.60.10.10 106 315 1.3E-21 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily Astex_2006 2c52cffb26fb58ec89801d453a53e0bb 415 SUPERFAMILY SSF118215 6 398 1.01E-104 T 13-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 Astex_2006 2c52cffb26fb58ec89801d453a53e0bb 415 Gene3D G3DSA:1.10.3860.10 1 405 1.3E-122 T 13-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 Astex_2006 2c52cffb26fb58ec89801d453a53e0bb 415 Pfam PF00375 Sodium:dicarboxylate symporter family 6 398 1.2E-115 T 13-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Astex_2006 2c52cffb26fb58ec89801d453a53e0bb 415 PRINTS PR00173 Glutamate-aspartate symporter signature 189 208 3.5E-24 T 13-10-2018 Astex_2006 2c52cffb26fb58ec89801d453a53e0bb 415 PRINTS PR00173 Glutamate-aspartate symporter signature 224 243 3.5E-24 T 13-10-2018 Astex_2006 2c52cffb26fb58ec89801d453a53e0bb 415 PRINTS PR00173 Glutamate-aspartate symporter signature 42 62 3.5E-24 T 13-10-2018 Astex_2006 2c52cffb26fb58ec89801d453a53e0bb 415 PRINTS PR00173 Glutamate-aspartate symporter signature 79 104 3.5E-24 T 13-10-2018 Astex_2006 2c52cffb26fb58ec89801d453a53e0bb 415 PRINTS PR00173 Glutamate-aspartate symporter signature 290 316 3.5E-24 T 13-10-2018 Astex_2006 2c52cffb26fb58ec89801d453a53e0bb 415 PRINTS PR00173 Glutamate-aspartate symporter signature 353 373 3.5E-24 T 13-10-2018 Astex_2006 2c52cffb26fb58ec89801d453a53e0bb 415 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 34 49 - T 13-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site Astex_2787 ae50aff7f5ed4f7e6062ff93dfcc5664 314 SUPERFAMILY SSF55048 130 200 4.58E-12 T 13-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding Astex_2787 ae50aff7f5ed4f7e6062ff93dfcc5664 314 Pfam PF00698 Acyl transferase domain 5 279 1.8E-40 T 13-10-2018 IPR014043 Acyl transferase Astex_2787 ae50aff7f5ed4f7e6062ff93dfcc5664 314 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 6 307 7.5E-41 T 13-10-2018 IPR020801 Polyketide synthase, acyl transferase domain Astex_2787 ae50aff7f5ed4f7e6062ff93dfcc5664 314 PIRSF PIRSF000446 1 314 1.1E-86 T 13-10-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 Astex_2787 ae50aff7f5ed4f7e6062ff93dfcc5664 314 Gene3D G3DSA:3.40.366.10 4 291 5.3E-90 T 13-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 Astex_2787 ae50aff7f5ed4f7e6062ff93dfcc5664 314 Gene3D G3DSA:3.30.70.250 130 200 5.3E-90 T 13-10-2018 Astex_2787 ae50aff7f5ed4f7e6062ff93dfcc5664 314 SUPERFAMILY SSF52151 2 310 2.35E-72 T 13-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase Astex_2787 ae50aff7f5ed4f7e6062ff93dfcc5664 314 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 2 293 4.7E-89 T 13-10-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 Astex_0879 d7f907b530b37b6e34b3cf6afb4a4820 425 SUPERFAMILY SSF51338 26 89 2.01E-11 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Astex_0879 d7f907b530b37b6e34b3cf6afb4a4820 425 Gene3D G3DSA:2.30.40.10 31 421 7.3E-151 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Astex_0879 d7f907b530b37b6e34b3cf6afb4a4820 425 SUPERFAMILY SSF51556 81 382 1.04E-101 T 13-10-2018 IPR032466 Metal-dependent hydrolase Astex_0879 d7f907b530b37b6e34b3cf6afb4a4820 425 Pfam PF01979 Amidohydrolase family 77 421 3.2E-55 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 Astex_0879 d7f907b530b37b6e34b3cf6afb4a4820 425 Gene3D G3DSA:3.20.20.140 83 384 7.3E-151 T 13-10-2018 Astex_0216 183dd4d30f03962e14e62b94679a7219 220 Pfam PF13630 SdpI/YhfL protein family 140 213 2.7E-20 T 13-10-2018 IPR025962 SdpI/YhfL protein family Astex_0216 183dd4d30f03962e14e62b94679a7219 220 Pfam PF07853 Protein of unknown function (DUF1648) 16 64 6.2E-8 T 13-10-2018 IPR012867 Domain of unknown function DUF1648 Astex_0216 183dd4d30f03962e14e62b94679a7219 220 PIRSF PIRSF038959 6 219 5.4E-40 T 13-10-2018 IPR026272 Immunity protein SdpI Astex_1826 eef7934c97ed7f349c8e39c99ac27fa3 44 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 13-10-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_1826 eef7934c97ed7f349c8e39c99ac27fa3 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 28 6.0E-7 T 13-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_1826 eef7934c97ed7f349c8e39c99ac27fa3 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 2 44 1.4E-23 T 13-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_1826 eef7934c97ed7f349c8e39c99ac27fa3 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 15.615 T 13-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_1826 eef7934c97ed7f349c8e39c99ac27fa3 44 Pfam PF00468 Ribosomal protein L34 2 44 1.9E-23 T 13-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0553 5611feb09e4e8afe48df721cef301969 489 Pfam PF06628 Catalase-related immune-responsive 416 476 2.5E-21 T 13-10-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Astex_0553 5611feb09e4e8afe48df721cef301969 489 SMART SM01060 7 392 9.4E-273 T 13-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Astex_0553 5611feb09e4e8afe48df721cef301969 489 Pfam PF00199 Catalase 7 389 2.7E-182 T 13-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Astex_0553 5611feb09e4e8afe48df721cef301969 489 Gene3D G3DSA:2.40.180.10 2 483 2.0E-215 T 13-10-2018 IPR037060 Catalase core domain superfamily GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Astex_0553 5611feb09e4e8afe48df721cef301969 489 PRINTS PR00067 Catalase signature 82 100 2.5E-71 T 13-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Astex_0553 5611feb09e4e8afe48df721cef301969 489 PRINTS PR00067 Catalase signature 319 345 2.5E-71 T 13-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Astex_0553 5611feb09e4e8afe48df721cef301969 489 PRINTS PR00067 Catalase signature 122 140 2.5E-71 T 13-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Astex_0553 5611feb09e4e8afe48df721cef301969 489 PRINTS PR00067 Catalase signature 103 120 2.5E-71 T 13-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Astex_0553 5611feb09e4e8afe48df721cef301969 489 PRINTS PR00067 Catalase signature 287 314 2.5E-71 T 13-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Astex_0553 5611feb09e4e8afe48df721cef301969 489 PRINTS PR00067 Catalase signature 20 43 2.5E-71 T 13-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Astex_0553 5611feb09e4e8afe48df721cef301969 489 SUPERFAMILY SSF56634 3 479 1.44E-203 T 13-10-2018 IPR020835 Catalase superfamily GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Astex_0553 5611feb09e4e8afe48df721cef301969 489 PIRSF PIRSF038928 1 480 1.2E-215 T 13-10-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Astex_0553 5611feb09e4e8afe48df721cef301969 489 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 332 340 - T 13-10-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Astex_0862 62a7a06c8269d293bb2c4e7efec0acb9 143 Pfam PF00472 RF-1 domain 7 132 3.8E-20 T 13-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 Astex_0862 62a7a06c8269d293bb2c4e7efec0acb9 143 SUPERFAMILY SSF110916 14 102 6.02E-12 T 13-10-2018 Astex_0862 62a7a06c8269d293bb2c4e7efec0acb9 143 Gene3D G3DSA:3.30.160.20 1 138 2.6E-35 T 13-10-2018 Astex_0862 62a7a06c8269d293bb2c4e7efec0acb9 143 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 21 37 - T 13-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 Astex_3067 a5edbccb93c5c178e1c572562322d835 252 SUPERFAMILY SSF56104 5 237 5.89E-79 T 13-10-2018 Astex_3067 a5edbccb93c5c178e1c572562322d835 252 ProSitePatterns PS01058 SAICAR synthetase signature 2. 174 182 - T 13-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Astex_3067 a5edbccb93c5c178e1c572562322d835 252 Gene3D G3DSA:3.30.470.20 86 225 9.7E-96 T 13-10-2018 Astex_3067 a5edbccb93c5c178e1c572562322d835 252 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 1 241 2.2E-68 T 13-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 Astex_3067 a5edbccb93c5c178e1c572562322d835 252 ProSitePatterns PS01057 SAICAR synthetase signature 1. 87 101 - T 13-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Astex_3067 a5edbccb93c5c178e1c572562322d835 252 Gene3D G3DSA:3.30.200.20 7 236 9.7E-96 T 13-10-2018 Astex_3067 a5edbccb93c5c178e1c572562322d835 252 Pfam PF01259 SAICAR synthetase 7 236 1.0E-62 T 13-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Astex_3067 a5edbccb93c5c178e1c572562322d835 252 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 5 239 32.796 T 13-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Astex_1369 033be2ca271903cc79301947cb226a2d 588 Gene3D G3DSA:3.20.20.80 79 514 6.3E-158 T 13-10-2018 Astex_1369 033be2ca271903cc79301947cb226a2d 588 Pfam PF00128 Alpha amylase, catalytic domain 88 316 8.9E-33 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Astex_1369 033be2ca271903cc79301947cb226a2d 588 Gene3D G3DSA:3.90.400.10 165 240 6.3E-158 T 13-10-2018 Astex_1369 033be2ca271903cc79301947cb226a2d 588 SMART SM00642 80 492 3.4E-25 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Astex_1369 033be2ca271903cc79301947cb226a2d 588 SUPERFAMILY SSF51445 75 514 5.72E-86 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_1369 033be2ca271903cc79301947cb226a2d 588 Gene3D G3DSA:1.10.1740.10 14 75 1.1E-9 T 13-10-2018 Astex_0512 fa03416350bc82720aedeca3fdccf7bc 70 Pfam PF09926 Uncharacterized small protein (DUF2158) 5 49 4.8E-14 T 13-10-2018 IPR019226 Protein of unknown function DUF2158 Astex_0656 04ae7ec84a1bd0f1c2af7247f7cbf4da 188 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 4 186 32.342 T 13-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 Astex_0656 04ae7ec84a1bd0f1c2af7247f7cbf4da 188 TIGRFAM TIGR00681 kdpC: K+-transporting ATPase, C subunit 6 185 5.1E-60 T 13-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 Astex_0656 04ae7ec84a1bd0f1c2af7247f7cbf4da 188 PIRSF PIRSF001296 3 188 2.5E-67 T 13-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 Astex_0656 04ae7ec84a1bd0f1c2af7247f7cbf4da 188 Pfam PF02669 K+-transporting ATPase, c chain 8 184 4.3E-66 T 13-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 Astex_2857 47614d6c33def7a1f8786bad75b68996 393 Pfam PF02684 Lipid-A-disaccharide synthetase 13 352 1.1E-82 T 13-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 Astex_2857 47614d6c33def7a1f8786bad75b68996 393 TIGRFAM TIGR00215 lpxB: lipid-A-disaccharide synthase 8 386 1.1E-68 T 13-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 Astex_2857 47614d6c33def7a1f8786bad75b68996 393 SUPERFAMILY SSF53756 11 369 1.67E-33 T 13-10-2018 Astex_1229 8afc8eddf848f584b24fed2bfcb7472e 337 Gene3D G3DSA:1.10.1530.10 18 329 2.7E-90 T 13-10-2018 Astex_1229 8afc8eddf848f584b24fed2bfcb7472e 337 Gene3D G3DSA:3.30.1370.60 65 304 2.7E-90 T 13-10-2018 Astex_1229 8afc8eddf848f584b24fed2bfcb7472e 337 SUPERFAMILY SSF89733 7 335 7.72E-93 T 13-10-2018 IPR036111 Malate/L-sulfolactate/L-lactate dehydrogenase-like superfamily GO:0016491|GO:0055114 Astex_1229 8afc8eddf848f584b24fed2bfcb7472e 337 Pfam PF02615 Malate/L-lactate dehydrogenase 9 332 4.8E-93 T 13-10-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0016491|GO:0055114 Astex_1229 8afc8eddf848f584b24fed2bfcb7472e 337 Gene3D G3DSA:3.30.60.50 180 227 2.7E-90 T 13-10-2018 Astex_3672 950ed0c7a81ebed6172edef2e8dd35a2 75 SUPERFAMILY SSF89447 4 63 8.2E-10 T 13-10-2018 IPR037914 SpoVT-AbrB domain superfamily Astex_3672 950ed0c7a81ebed6172edef2e8dd35a2 75 TIGRFAM TIGR02609 doc_partner: putative addiction module antidote 4 75 7.7E-17 T 13-10-2018 IPR013432 Putative addiction module antidote Astex_3672 950ed0c7a81ebed6172edef2e8dd35a2 75 Gene3D G3DSA:2.10.260.10 1 43 4.5E-5 T 13-10-2018 Astex_3672 950ed0c7a81ebed6172edef2e8dd35a2 75 SMART SM00966 7 51 5.9E-6 T 13-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 Astex_3672 950ed0c7a81ebed6172edef2e8dd35a2 75 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 40 3.7E-6 T 13-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 Astex_0741 70e8100fa4d92b7997edb6a58c460301 309 SUPERFAMILY SSF52309 191 269 1.59E-6 T 13-10-2018 Astex_0741 70e8100fa4d92b7997edb6a58c460301 309 Gene3D G3DSA:3.40.50.450 183 288 5.1E-6 T 13-10-2018 Astex_0836 644f867e9f0104d11e4d87c9ae406a85 562 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 69 247 9.5E-6 T 13-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like Astex_3148 e23844f46da9a34468621209b6259352 126 TIGRFAM TIGR00494 crcB: protein CrcB 5 120 5.0E-26 T 13-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 Astex_3148 e23844f46da9a34468621209b6259352 126 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 4 122 18.422 T 13-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 Astex_3148 e23844f46da9a34468621209b6259352 126 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 5 117 1.2E-23 T 13-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 Astex_3148 e23844f46da9a34468621209b6259352 126 SUPERFAMILY SSF52255 8 64 8.37E-5 T 13-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 Astex_1541 889a46628ed2075fe338f5852c71aac0 442 Pfam PF01471 Putative peptidoglycan binding domain 376 421 8.0E-9 T 13-10-2018 IPR002477 Peptidoglycan binding-like Astex_1541 889a46628ed2075fe338f5852c71aac0 442 TIGRFAM TIGR02283 MltB_2: lytic murein transglycosylase 60 356 8.3E-102 T 13-10-2018 IPR011970 Lytic murein transglycosylase Astex_1541 889a46628ed2075fe338f5852c71aac0 442 SUPERFAMILY SSF53955 51 357 2.33E-87 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily Astex_1541 889a46628ed2075fe338f5852c71aac0 442 Gene3D G3DSA:1.10.101.10 374 431 4.5E-9 T 13-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 Astex_1541 889a46628ed2075fe338f5852c71aac0 442 Pfam PF13406 Transglycosylase SLT domain 61 352 4.0E-99 T 13-10-2018 IPR031304 Transglycosylase SLT domain 2 Astex_1541 889a46628ed2075fe338f5852c71aac0 442 Gene3D G3DSA:1.10.8.350 73 235 3.1E-73 T 13-10-2018 Astex_1541 889a46628ed2075fe338f5852c71aac0 442 Gene3D G3DSA:1.10.530.10 103 348 3.1E-73 T 13-10-2018 Astex_1541 889a46628ed2075fe338f5852c71aac0 442 SUPERFAMILY SSF47090 363 427 2.54E-12 T 13-10-2018 IPR036365 PGBD-like superfamily Astex_1637 f71c57cda61455149825cff30bcc03a0 277 Gene3D G3DSA:3.60.21.10 1 270 1.6E-99 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like Astex_1637 f71c57cda61455149825cff30bcc03a0 277 PIRSF PIRSF004789 1 268 4.9E-86 T 13-10-2018 IPR005235 Metallophosphoesterase, YmdB-like Astex_1637 f71c57cda61455149825cff30bcc03a0 277 SUPERFAMILY SSF56300 1 261 4.51E-80 T 13-10-2018 Astex_1637 f71c57cda61455149825cff30bcc03a0 277 Pfam PF13277 YmdB-like protein 5 260 5.9E-98 T 13-10-2018 IPR005235 Metallophosphoesterase, YmdB-like Astex_3842 ba802fb9925daa75df85289478434612 1048 SUPERFAMILY SSF82693 46 127 2.3E-19 T 13-10-2018 Astex_3842 ba802fb9925daa75df85289478434612 1048 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 9.9E-22 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3842 ba802fb9925daa75df85289478434612 1048 PRINTS PR00702 Acriflavin resistance protein family signature 334 357 9.9E-22 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3842 ba802fb9925daa75df85289478434612 1048 PRINTS PR00702 Acriflavin resistance protein family signature 389 413 9.9E-22 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3842 ba802fb9925daa75df85289478434612 1048 PRINTS PR00702 Acriflavin resistance protein family signature 552 569 9.9E-22 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3842 ba802fb9925daa75df85289478434612 1048 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 9.9E-22 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3842 ba802fb9925daa75df85289478434612 1048 PRINTS PR00702 Acriflavin resistance protein family signature 361 382 9.9E-22 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3842 ba802fb9925daa75df85289478434612 1048 Gene3D G3DSA:1.20.1640.10 514 1030 2.4E-262 T 13-10-2018 Astex_3842 ba802fb9925daa75df85289478434612 1048 SUPERFAMILY SSF82693 137 328 7.85E-23 T 13-10-2018 Astex_3842 ba802fb9925daa75df85289478434612 1048 SUPERFAMILY SSF82866 806 1038 6.54E-46 T 13-10-2018 Astex_3842 ba802fb9925daa75df85289478434612 1048 Gene3D G3DSA:3.30.70.1430 569 671 2.4E-262 T 13-10-2018 Astex_3842 ba802fb9925daa75df85289478434612 1048 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1043 0.0 T 13-10-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 Astex_3842 ba802fb9925daa75df85289478434612 1048 SUPERFAMILY SSF82714 185 269 1.96E-19 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Astex_3842 ba802fb9925daa75df85289478434612 1048 Pfam PF00873 AcrB/AcrD/AcrF family 6 1034 3.2E-241 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3842 ba802fb9925daa75df85289478434612 1048 SUPERFAMILY SSF82714 723 806 6.8E-18 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Astex_3842 ba802fb9925daa75df85289478434612 1048 Gene3D G3DSA:3.30.2090.10 723 811 2.4E-262 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Astex_3842 ba802fb9925daa75df85289478434612 1048 Gene3D G3DSA:3.30.70.1320 135 328 2.4E-262 T 13-10-2018 Astex_3842 ba802fb9925daa75df85289478434612 1048 Gene3D G3DSA:3.30.70.1430 42 819 2.4E-262 T 13-10-2018 Astex_3842 ba802fb9925daa75df85289478434612 1048 SUPERFAMILY SSF82866 294 505 1.01E-39 T 13-10-2018 Astex_3842 ba802fb9925daa75df85289478434612 1048 Gene3D G3DSA:1.20.1640.10 15 513 2.4E-262 T 13-10-2018 Astex_3842 ba802fb9925daa75df85289478434612 1048 Gene3D G3DSA:3.30.2090.10 182 274 2.4E-262 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Astex_3842 ba802fb9925daa75df85289478434612 1048 Gene3D G3DSA:3.30.70.1440 672 869 2.4E-262 T 13-10-2018 Astex_0065 4d688e1f38664884beb9513b1382fd23 556 Gene3D G3DSA:1.20.1480.50 165 265 1.1E-13 T 13-10-2018 Astex_0065 4d688e1f38664884beb9513b1382fd23 556 Gene3D G3DSA:1.10.287.950 266 555 1.9E-55 T 13-10-2018 Astex_0065 4d688e1f38664884beb9513b1382fd23 556 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 394 421 3.1E-20 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_0065 4d688e1f38664884beb9513b1382fd23 556 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 317 346 3.1E-20 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_0065 4d688e1f38664884beb9513b1382fd23 556 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 423 452 3.1E-20 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_0065 4d688e1f38664884beb9513b1382fd23 556 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 471 500 3.1E-20 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_0065 4d688e1f38664884beb9513b1382fd23 556 SMART SM00304 207 260 1.2E-6 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Astex_0065 4d688e1f38664884beb9513b1382fd23 556 SUPERFAMILY SSF58104 236 549 2.35E-60 T 13-10-2018 Astex_0065 4d688e1f38664884beb9513b1382fd23 556 SMART SM00283 296 550 8.7E-45 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_0065 4d688e1f38664884beb9513b1382fd23 556 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 364 521 4.0E-30 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_0065 4d688e1f38664884beb9513b1382fd23 556 Pfam PF12729 Four helix bundle sensory module for signal transduction 4 177 3.8E-11 T 13-10-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain Astex_0065 4d688e1f38664884beb9513b1382fd23 556 Pfam PF00672 HAMP domain 207 251 2.5E-7 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Astex_2223 6e7e516c12ce2ebb2311de50a81b5b15 388 SMART SM00984 300 387 6.9E-17 T 13-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 Astex_2223 6e7e516c12ce2ebb2311de50a81b5b15 388 PIRSF PIRSF000124 1 388 7.9E-132 T 13-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 Astex_2223 6e7e516c12ce2ebb2311de50a81b5b15 388 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 192 281 2.1E-27 T 13-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 Astex_2223 6e7e516c12ce2ebb2311de50a81b5b15 388 Gene3D G3DSA:3.40.50.720 222 388 1.8E-66 T 13-10-2018 Astex_2223 6e7e516c12ce2ebb2311de50a81b5b15 388 Gene3D G3DSA:3.40.50.720 1 193 2.0E-57 T 13-10-2018 Astex_2223 6e7e516c12ce2ebb2311de50a81b5b15 388 SUPERFAMILY SSF52413 283 387 5.75E-28 T 13-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 Astex_2223 6e7e516c12ce2ebb2311de50a81b5b15 388 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 301 375 1.1E-9 T 13-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 Astex_2223 6e7e516c12ce2ebb2311de50a81b5b15 388 PIRSF PIRSF500134 1 342 2.1E-118 T 13-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 Astex_2223 6e7e516c12ce2ebb2311de50a81b5b15 388 PIRSF PIRSF500134 338 388 0.17 T 13-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 Astex_2223 6e7e516c12ce2ebb2311de50a81b5b15 388 SUPERFAMILY SSF51735 1 194 1.3E-47 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_2223 6e7e516c12ce2ebb2311de50a81b5b15 388 SUPERFAMILY SSF48179 192 287 8.28E-30 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Astex_2223 6e7e516c12ce2ebb2311de50a81b5b15 388 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 377 8.6E-104 T 13-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 Astex_2223 6e7e516c12ce2ebb2311de50a81b5b15 388 Gene3D G3DSA:1.20.5.100 194 220 1.7E-18 T 13-10-2018 Astex_2223 6e7e516c12ce2ebb2311de50a81b5b15 388 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 168 5.3E-33 T 13-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 Astex_2069 a5f56773c0afecfa2ede3745a494629f 309 Gene3D G3DSA:3.40.190.290 92 294 4.7E-57 T 13-10-2018 Astex_2069 a5f56773c0afecfa2ede3745a494629f 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.7E-6 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_2069 a5f56773c0afecfa2ede3745a494629f 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.7E-6 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_2069 a5f56773c0afecfa2ede3745a494629f 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.7E-6 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_2069 a5f56773c0afecfa2ede3745a494629f 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 63 2.4E-17 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_2069 a5f56773c0afecfa2ede3745a494629f 309 SUPERFAMILY SSF53850 90 298 3.44E-42 T 13-10-2018 Astex_2069 a5f56773c0afecfa2ede3745a494629f 309 Gene3D G3DSA:1.10.10.10 4 90 6.6E-25 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_2069 a5f56773c0afecfa2ede3745a494629f 309 Pfam PF03466 LysR substrate binding domain 89 295 4.2E-41 T 13-10-2018 IPR005119 LysR, substrate-binding Astex_2069 a5f56773c0afecfa2ede3745a494629f 309 SUPERFAMILY SSF46785 4 87 4.08E-20 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_2615 357f67f8ce821e8d63639977213aa313 326 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 135 258 2.7E-43 T 13-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_2615 357f67f8ce821e8d63639977213aa313 326 SUPERFAMILY SSF81464 30 129 1.01E-25 T 13-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_2615 357f67f8ce821e8d63639977213aa313 326 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 35 122 4.5E-23 T 13-10-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_2615 357f67f8ce821e8d63639977213aa313 326 Gene3D G3DSA:2.60.40.420 131 270 4.8E-49 T 13-10-2018 IPR008972 Cupredoxin Astex_2615 357f67f8ce821e8d63639977213aa313 326 Gene3D G3DSA:1.10.287.90 34 130 3.0E-32 T 13-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_2615 357f67f8ce821e8d63639977213aa313 326 PRINTS PR01166 Cytochrome c oxidase subunit II signature 96 108 1.0E-45 T 13-10-2018 Astex_2615 357f67f8ce821e8d63639977213aa313 326 PRINTS PR01166 Cytochrome c oxidase subunit II signature 222 239 1.0E-45 T 13-10-2018 Astex_2615 357f67f8ce821e8d63639977213aa313 326 PRINTS PR01166 Cytochrome c oxidase subunit II signature 178 199 1.0E-45 T 13-10-2018 Astex_2615 357f67f8ce821e8d63639977213aa313 326 PRINTS PR01166 Cytochrome c oxidase subunit II signature 130 149 1.0E-45 T 13-10-2018 Astex_2615 357f67f8ce821e8d63639977213aa313 326 PRINTS PR01166 Cytochrome c oxidase subunit II signature 240 257 1.0E-45 T 13-10-2018 Astex_2615 357f67f8ce821e8d63639977213aa313 326 PRINTS PR01166 Cytochrome c oxidase subunit II signature 108 128 1.0E-45 T 13-10-2018 Astex_2615 357f67f8ce821e8d63639977213aa313 326 PRINTS PR01166 Cytochrome c oxidase subunit II signature 202 222 1.0E-45 T 13-10-2018 Astex_2615 357f67f8ce821e8d63639977213aa313 326 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 203 251 - T 13-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_2615 357f67f8ce821e8d63639977213aa313 326 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 59 267 4.0E-59 T 13-10-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_2615 357f67f8ce821e8d63639977213aa313 326 SUPERFAMILY SSF49503 130 268 3.22E-49 T 13-10-2018 IPR008972 Cupredoxin Astex_2376 172a9b3285326ddef1a39f99a697a0dc 406 SUPERFAMILY SSF103473 7 395 6.41E-60 T 13-10-2018 IPR036259 MFS transporter superfamily Astex_2376 172a9b3285326ddef1a39f99a697a0dc 406 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 15 395 1.3E-87 T 13-10-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0006855|GO:0015238|GO:0016021 Astex_2376 172a9b3285326ddef1a39f99a697a0dc 406 Pfam PF07690 Major Facilitator Superfamily 25 364 4.2E-43 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Astex_2376 172a9b3285326ddef1a39f99a697a0dc 406 Gene3D G3DSA:1.20.1720.10 17 396 6.5E-98 T 13-10-2018 Astex_1397 479eceacb94fd3666bb3ea3e8d86b913 358 Gene3D G3DSA:3.40.50.1820 53 350 3.1E-51 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1397 479eceacb94fd3666bb3ea3e8d86b913 358 Pfam PF07859 alpha/beta hydrolase fold 121 326 1.7E-40 T 13-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 Astex_1397 479eceacb94fd3666bb3ea3e8d86b913 358 SUPERFAMILY SSF53474 95 347 4.94E-40 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1402 f3bfdbcd19607a7c762a15d610441545 303 SUPERFAMILY SSF48576 15 285 1.02E-73 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily Astex_1402 f3bfdbcd19607a7c762a15d610441545 303 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 221 233 - T 13-10-2018 IPR033749 Polyprenyl synthetase, conserved site Astex_1402 f3bfdbcd19607a7c762a15d610441545 303 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 91 107 - T 13-10-2018 IPR033749 Polyprenyl synthetase, conserved site Astex_1402 f3bfdbcd19607a7c762a15d610441545 303 Pfam PF00348 Polyprenyl synthetase 41 273 2.5E-47 T 13-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 Astex_1402 f3bfdbcd19607a7c762a15d610441545 303 Gene3D G3DSA:1.10.600.10 12 303 4.2E-88 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily Astex_0237 e10f2ac228e59909a0c73cb092ec8a27 993 Pfam PF02779 Transketolase, pyrimidine binding domain 638 833 3.2E-66 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain Astex_0237 e10f2ac228e59909a0c73cb092ec8a27 993 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 90 991 0.0 T 13-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 Astex_0237 e10f2ac228e59909a0c73cb092ec8a27 993 SUPERFAMILY SSF52518 622 838 1.47E-52 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold Astex_0237 e10f2ac228e59909a0c73cb092ec8a27 993 SMART SM00861 639 832 1.4E-64 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain Astex_0237 e10f2ac228e59909a0c73cb092ec8a27 993 Gene3D G3DSA:3.40.50.11610 775 990 2.6E-171 T 13-10-2018 Astex_0237 e10f2ac228e59909a0c73cb092ec8a27 993 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 15 53 4.5E-16 T 13-10-2018 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 Astex_0237 e10f2ac228e59909a0c73cb092ec8a27 993 Gene3D G3DSA:3.40.50.970 202 575 4.9E-144 T 13-10-2018 Astex_0237 e10f2ac228e59909a0c73cb092ec8a27 993 Gene3D G3DSA:3.40.50.12470 599 855 2.6E-171 T 13-10-2018 Astex_0237 e10f2ac228e59909a0c73cb092ec8a27 993 PIRSF PIRSF000157 3 993 0.0 T 13-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 Astex_0237 e10f2ac228e59909a0c73cb092ec8a27 993 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 837 992 1.0E-52 T 13-10-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 Astex_0237 e10f2ac228e59909a0c73cb092ec8a27 993 SUPERFAMILY SSF52518 160 582 6.48E-90 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold Astex_0237 e10f2ac228e59909a0c73cb092ec8a27 993 Pfam PF00676 Dehydrogenase E1 component 251 572 1.6E-53 T 13-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 Astex_0237 e10f2ac228e59909a0c73cb092ec8a27 993 Gene3D G3DSA:1.10.287.1150 120 201 1.2E-23 T 13-10-2018 Astex_1116 b1c8a737ee2399bd68b43cee5414faab 253 ProSitePatterns PS00449 ATP synthase a subunit signature. 174 183 - T 13-10-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_1116 b1c8a737ee2399bd68b43cee5414faab 253 Gene3D G3DSA:1.20.120.220 83 251 1.4E-31 T 13-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_1116 b1c8a737ee2399bd68b43cee5414faab 253 PRINTS PR00123 ATP synthase A subunit signature 151 166 6.3E-28 T 13-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_1116 b1c8a737ee2399bd68b43cee5414faab 253 PRINTS PR00123 ATP synthase A subunit signature 171 193 6.3E-28 T 13-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_1116 b1c8a737ee2399bd68b43cee5414faab 253 PRINTS PR00123 ATP synthase A subunit signature 91 107 6.3E-28 T 13-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_1116 b1c8a737ee2399bd68b43cee5414faab 253 PRINTS PR00123 ATP synthase A subunit signature 231 246 6.3E-28 T 13-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_1116 b1c8a737ee2399bd68b43cee5414faab 253 Hamap MF_01393 ATP synthase subunit a [atpB]. 6 251 14.802 T 13-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_1116 b1c8a737ee2399bd68b43cee5414faab 253 Pfam PF00119 ATP synthase A chain 37 244 8.7E-52 T 13-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_1116 b1c8a737ee2399bd68b43cee5414faab 253 SUPERFAMILY SSF81336 83 245 2.22E-39 T 13-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_1116 b1c8a737ee2399bd68b43cee5414faab 253 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 5 247 2.9E-56 T 13-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_2938 fdeacdcbe68997384103f24da105fdb6 156 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 7 147 5.6E-45 T 13-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Astex_2938 fdeacdcbe68997384103f24da105fdb6 156 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 2 150 25.049 T 13-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Astex_2938 fdeacdcbe68997384103f24da105fdb6 156 Gene3D G3DSA:3.40.50.960 1 151 1.3E-50 T 13-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Astex_2938 fdeacdcbe68997384103f24da105fdb6 156 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 8 145 8.7E-33 T 13-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Astex_2938 fdeacdcbe68997384103f24da105fdb6 156 SUPERFAMILY SSF52121 4 152 8.37E-49 T 13-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Astex_1372 59c5274b5bc73e15f7923a24775f0041 847 Pfam PF13298 DNA polymerase Ligase (LigD) 33 137 9.6E-40 T 13-10-2018 IPR014144 DNA ligase D, 3'-phosphoesterase domain Astex_1372 59c5274b5bc73e15f7923a24775f0041 847 Gene3D G3DSA:3.90.920.30 564 846 3.1E-99 T 13-10-2018 Astex_1372 59c5274b5bc73e15f7923a24775f0041 847 Gene3D G3DSA:3.30.470.30 240 356 1.3E-45 T 13-10-2018 Astex_1372 59c5274b5bc73e15f7923a24775f0041 847 Pfam PF04679 ATP dependent DNA ligase C terminal region 418 511 1.7E-24 T 13-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 Astex_1372 59c5274b5bc73e15f7923a24775f0041 847 TIGRFAM TIGR02777 LigD_PE_dom: DNA ligase D, 3'-phosphoesterase domain 4 159 6.2E-69 T 13-10-2018 IPR014144 DNA ligase D, 3'-phosphoesterase domain Astex_1372 59c5274b5bc73e15f7923a24775f0041 847 Pfam PF01068 ATP dependent DNA ligase domain 228 399 2.9E-27 T 13-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 Astex_1372 59c5274b5bc73e15f7923a24775f0041 847 TIGRFAM TIGR02776 NHEJ_ligase_prk: DNA ligase D 226 830 3.1E-205 T 13-10-2018 IPR014143 DNA ligase D Astex_1372 59c5274b5bc73e15f7923a24775f0041 847 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 557 801 3.8E-92 T 13-10-2018 IPR014145 DNA ligase D, polymerase domain Astex_1372 59c5274b5bc73e15f7923a24775f0041 847 Gene3D G3DSA:2.40.50.140 401 519 3.2E-35 T 13-10-2018 Astex_1372 59c5274b5bc73e15f7923a24775f0041 847 Gene3D G3DSA:3.30.1490.70 225 397 1.3E-45 T 13-10-2018 Astex_1372 59c5274b5bc73e15f7923a24775f0041 847 SUPERFAMILY SSF50249 403 518 8.14E-27 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Astex_1372 59c5274b5bc73e15f7923a24775f0041 847 TIGRFAM TIGR02779 NHEJ_ligase_lig: DNA ligase D, ligase domain 217 517 6.9E-100 T 13-10-2018 IPR014146 DNA ligase D, ligase domain Astex_1372 59c5274b5bc73e15f7923a24775f0041 847 SUPERFAMILY SSF56091 189 400 5.76E-48 T 13-10-2018 Astex_1998 b4c6528c1cc8302f54d566d9b4e4250e 615 Pfam PF05227 CHASE3 domain 48 167 7.8E-8 T 13-10-2018 IPR007891 CHASE3 Astex_1998 b4c6528c1cc8302f54d566d9b4e4250e 615 Gene3D G3DSA:1.20.1440.210 48 172 3.5E-5 T 13-10-2018 Astex_1998 b4c6528c1cc8302f54d566d9b4e4250e 615 PRINTS PR00344 Bacterial sensor protein C-terminal signature 526 540 4.4E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1998 b4c6528c1cc8302f54d566d9b4e4250e 615 PRINTS PR00344 Bacterial sensor protein C-terminal signature 544 554 4.4E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1998 b4c6528c1cc8302f54d566d9b4e4250e 615 PRINTS PR00344 Bacterial sensor protein C-terminal signature 559 577 4.4E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1998 b4c6528c1cc8302f54d566d9b4e4250e 615 PRINTS PR00344 Bacterial sensor protein C-terminal signature 583 596 4.4E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1998 b4c6528c1cc8302f54d566d9b4e4250e 615 SMART SM00091 226 294 7.4E-7 T 13-10-2018 IPR000014 PAS domain Astex_1998 b4c6528c1cc8302f54d566d9b4e4250e 615 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 225 350 1.1E-16 T 13-10-2018 IPR000014 PAS domain Astex_1998 b4c6528c1cc8302f54d566d9b4e4250e 615 Pfam PF08447 PAS fold 249 337 2.1E-19 T 13-10-2018 IPR013655 PAS fold-3 GO:0005515 Astex_1998 b4c6528c1cc8302f54d566d9b4e4250e 615 Pfam PF00512 His Kinase A (phospho-acceptor) domain 358 444 3.0E-6 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_1998 b4c6528c1cc8302f54d566d9b4e4250e 615 Gene3D G3DSA:2.10.70.100 297 343 4.3E-8 T 13-10-2018 Astex_1998 b4c6528c1cc8302f54d566d9b4e4250e 615 SMART SM00387 487 599 6.4E-30 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_1998 b4c6528c1cc8302f54d566d9b4e4250e 615 Gene3D G3DSA:3.30.565.10 449 601 1.1E-33 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_1998 b4c6528c1cc8302f54d566d9b4e4250e 615 SUPERFAMILY SSF55874 437 597 8.38E-35 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_1998 b4c6528c1cc8302f54d566d9b4e4250e 615 SMART SM00086 301 343 1.9E-6 T 13-10-2018 IPR001610 PAC motif Astex_1998 b4c6528c1cc8302f54d566d9b4e4250e 615 SUPERFAMILY SSF55785 232 345 3.38E-21 T 13-10-2018 IPR035965 PAS domain superfamily Astex_1998 b4c6528c1cc8302f54d566d9b4e4250e 615 Gene3D G3DSA:1.10.287.130 344 446 6.0E-10 T 13-10-2018 Astex_1998 b4c6528c1cc8302f54d566d9b4e4250e 615 Gene3D G3DSA:3.30.450.20 225 294 1.5E-15 T 13-10-2018 Astex_1998 b4c6528c1cc8302f54d566d9b4e4250e 615 SUPERFAMILY SSF47384 344 444 3.34E-9 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Astex_1998 b4c6528c1cc8302f54d566d9b4e4250e 615 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 488 597 5.7E-21 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_2113 2533d80f1f82956bbcdf32b07754f477 643 Gene3D G3DSA:1.10.390.10 347 502 5.4E-49 T 13-10-2018 IPR027268 Peptidase M4/M1, CTD superfamily Astex_2113 2533d80f1f82956bbcdf32b07754f477 643 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 233 248 1.4E-16 T 13-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Astex_2113 2533d80f1f82956bbcdf32b07754f477 643 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 307 317 1.4E-16 T 13-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Astex_2113 2533d80f1f82956bbcdf32b07754f477 643 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 334 349 1.4E-16 T 13-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Astex_2113 2533d80f1f82956bbcdf32b07754f477 643 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 181 196 1.4E-16 T 13-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Astex_2113 2533d80f1f82956bbcdf32b07754f477 643 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 353 365 1.4E-16 T 13-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Astex_2113 2533d80f1f82956bbcdf32b07754f477 643 Gene3D G3DSA:1.25.40.320 503 643 1.3E-47 T 13-10-2018 IPR038502 Peptidase M1 LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily Astex_2113 2533d80f1f82956bbcdf32b07754f477 643 Gene3D G3DSA:1.10.1740.60 250 346 1.9E-40 T 13-10-2018 Astex_2113 2533d80f1f82956bbcdf32b07754f477 643 Pfam PF01433 Peptidase family M1 domain 259 471 8.1E-49 T 13-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Astex_2113 2533d80f1f82956bbcdf32b07754f477 643 Gene3D G3DSA:2.60.40.1730 60 249 2.1E-57 T 13-10-2018 Astex_2113 2533d80f1f82956bbcdf32b07754f477 643 Pfam PF09127 Leukotriene A4 hydrolase, C-terminal 530 640 2.0E-27 T 13-10-2018 IPR015211 Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal GO:0008237|GO:0008270 Astex_2113 2533d80f1f82956bbcdf32b07754f477 643 SUPERFAMILY SSF55486 256 495 2.34E-66 T 13-10-2018 Astex_2113 2533d80f1f82956bbcdf32b07754f477 643 SUPERFAMILY SSF48371 517 641 1.61E-35 T 13-10-2018 IPR016024 Armadillo-type fold Astex_2113 2533d80f1f82956bbcdf32b07754f477 643 SMART SM01263 503 642 9.4E-43 T 13-10-2018 IPR015211 Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal GO:0008237|GO:0008270 Astex_2113 2533d80f1f82956bbcdf32b07754f477 643 SUPERFAMILY SSF63737 50 250 4.58E-34 T 13-10-2018 Astex_3452 09bc40875576b94b342b0712a72cee7b 186 SUPERFAMILY SSF52540 15 178 5.89E-29 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_3452 09bc40875576b94b342b0712a72cee7b 186 Gene3D G3DSA:3.40.50.300 16 185 3.6E-50 T 13-10-2018 Astex_3452 09bc40875576b94b342b0712a72cee7b 186 Pfam PF01202 Shikimate kinase 24 176 1.6E-45 T 13-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 Astex_3452 09bc40875576b94b342b0712a72cee7b 186 Hamap MF_00109 Shikimate kinase [aroK]. 15 180 26.253 T 13-10-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 Astex_3452 09bc40875576b94b342b0712a72cee7b 186 PRINTS PR01100 Shikimate kinase family signature 18 33 4.1E-19 T 13-10-2018 Astex_3452 09bc40875576b94b342b0712a72cee7b 186 PRINTS PR01100 Shikimate kinase family signature 42 55 4.1E-19 T 13-10-2018 Astex_3452 09bc40875576b94b342b0712a72cee7b 186 PRINTS PR01100 Shikimate kinase family signature 88 97 4.1E-19 T 13-10-2018 Astex_3452 09bc40875576b94b342b0712a72cee7b 186 PRINTS PR01100 Shikimate kinase family signature 70 78 4.1E-19 T 13-10-2018 Astex_3452 09bc40875576b94b342b0712a72cee7b 186 PRINTS PR01100 Shikimate kinase family signature 109 126 4.1E-19 T 13-10-2018 Astex_3452 09bc40875576b94b342b0712a72cee7b 186 ProSitePatterns PS01128 Shikimate kinase signature. 71 96 - T 13-10-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 Astex_0875 b4b5ca9f2b0b6b0c11e9b248b1ef8dc5 847 Pfam PF00593 TonB dependent receptor 371 845 1.9E-33 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_0875 b4b5ca9f2b0b6b0c11e9b248b1ef8dc5 847 SUPERFAMILY SSF56935 49 847 1.14E-76 T 13-10-2018 Astex_0875 b4b5ca9f2b0b6b0c11e9b248b1ef8dc5 847 Pfam PF07715 TonB-dependent Receptor Plug Domain 77 182 6.2E-11 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_0875 b4b5ca9f2b0b6b0c11e9b248b1ef8dc5 847 Gene3D G3DSA:2.170.130.10 48 188 3.0E-14 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_2873 488e03662b8b37fdea860d8714592e22 381 Hamap MF_01520 Bifunctional enzyme IspD/IspF [ispDF]. 1 380 41.917 T 13-10-2018 IPR026596 Bifunctional enzyme IspD/IspF KEGG: 00900+4.6.1.12+2.7.7.60|MetaCyc: PWY-7560 Astex_2873 488e03662b8b37fdea860d8714592e22 381 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 224 379 33.411 T 13-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 Astex_2873 488e03662b8b37fdea860d8714592e22 381 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 5 219 1.7E-56 T 13-10-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 Astex_2873 488e03662b8b37fdea860d8714592e22 381 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 258 273 - T 13-10-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 Astex_2873 488e03662b8b37fdea860d8714592e22 381 SUPERFAMILY SSF69765 223 378 4.19E-63 T 13-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 Astex_2873 488e03662b8b37fdea860d8714592e22 381 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 98 105 - T 13-10-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 Astex_2873 488e03662b8b37fdea860d8714592e22 381 Pfam PF02542 YgbB family 224 377 1.4E-61 T 13-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 Astex_2873 488e03662b8b37fdea860d8714592e22 381 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 2 219 36.026 T 13-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 Astex_2873 488e03662b8b37fdea860d8714592e22 381 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 5 219 2.4E-61 T 13-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 Astex_2873 488e03662b8b37fdea860d8714592e22 381 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 225 377 2.8E-64 T 13-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 Astex_2873 488e03662b8b37fdea860d8714592e22 381 SUPERFAMILY SSF53448 3 219 2.93E-49 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_2873 488e03662b8b37fdea860d8714592e22 381 Gene3D G3DSA:3.90.550.10 2 225 1.5E-66 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_2873 488e03662b8b37fdea860d8714592e22 381 Gene3D G3DSA:3.30.1330.50 226 379 3.4E-65 T 13-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 Astex_3679 2772318bd070a8b9ddcbe6e605576939 479 SUPERFAMILY SSF103473 20 473 5.49E-76 T 13-10-2018 IPR036259 MFS transporter superfamily Astex_3679 2772318bd070a8b9ddcbe6e605576939 479 PRINTS PR00171 Sugar transporter signature 400 412 2.4E-18 T 13-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 Astex_3679 2772318bd070a8b9ddcbe6e605576939 479 PRINTS PR00171 Sugar transporter signature 121 140 2.4E-18 T 13-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 Astex_3679 2772318bd070a8b9ddcbe6e605576939 479 PRINTS PR00171 Sugar transporter signature 292 302 2.4E-18 T 13-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 Astex_3679 2772318bd070a8b9ddcbe6e605576939 479 PRINTS PR00171 Sugar transporter signature 37 47 2.4E-18 T 13-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 Astex_3679 2772318bd070a8b9ddcbe6e605576939 479 PRINTS PR00171 Sugar transporter signature 377 398 2.4E-18 T 13-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 Astex_3679 2772318bd070a8b9ddcbe6e605576939 479 Gene3D G3DSA:1.20.1250.20 20 475 1.1E-129 T 13-10-2018 Astex_3679 2772318bd070a8b9ddcbe6e605576939 479 Pfam PF00083 Sugar (and other) transporter 31 474 2.3E-115 T 13-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 Astex_3679 2772318bd070a8b9ddcbe6e605576939 479 ProSitePatterns PS00217 Sugar transport proteins signature 2. 126 151 - T 13-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Astex_3679 2772318bd070a8b9ddcbe6e605576939 479 ProSitePatterns PS00216 Sugar transport proteins signature 1. 84 101 - T 13-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Astex_3679 2772318bd070a8b9ddcbe6e605576939 479 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 19 472 1.2E-110 T 13-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 Astex_1000 c207748e996bc179826287b48e561a9f 238 SMART SM00235 3 144 1.0E-5 T 13-10-2018 IPR006026 Peptidase, metallopeptidase GO:0006508|GO:0008237|GO:0008270 Astex_1000 c207748e996bc179826287b48e561a9f 238 SUPERFAMILY SSF55486 6 181 2.07E-21 T 13-10-2018 Astex_1000 c207748e996bc179826287b48e561a9f 238 PRINTS PR00480 Astacin family signature 115 132 8.0E-7 T 13-10-2018 IPR001506 Peptidase M12A GO:0004222|GO:0006508 Astex_1000 c207748e996bc179826287b48e561a9f 238 PRINTS PR00480 Astacin family signature 45 63 8.0E-7 T 13-10-2018 IPR001506 Peptidase M12A GO:0004222|GO:0006508 Astex_1000 c207748e996bc179826287b48e561a9f 238 PRINTS PR00480 Astacin family signature 96 114 8.0E-7 T 13-10-2018 IPR001506 Peptidase M12A GO:0004222|GO:0006508 Astex_1000 c207748e996bc179826287b48e561a9f 238 Gene3D G3DSA:3.40.390.10 3 234 5.0E-25 T 13-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 Astex_1000 c207748e996bc179826287b48e561a9f 238 Pfam PF01400 Astacin (Peptidase family M12A) 43 179 2.1E-15 T 13-10-2018 IPR001506 Peptidase M12A GO:0004222|GO:0006508 Astex_3509 542a87423ceff0873cc668dc5d9cc5dc 448 SUPERFAMILY SSF51011 368 447 2.4E-7 T 13-10-2018 Astex_3509 542a87423ceff0873cc668dc5d9cc5dc 448 SUPERFAMILY SSF51445 34 361 1.35E-72 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_3509 542a87423ceff0873cc668dc5d9cc5dc 448 Gene3D G3DSA:2.60.40.1180 364 448 5.1E-20 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta Astex_3509 542a87423ceff0873cc668dc5d9cc5dc 448 Gene3D G3DSA:3.20.20.70 21 362 1.3E-133 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_3509 542a87423ceff0873cc668dc5d9cc5dc 448 Pfam PF16499 Alpha galactosidase A 39 144 8.4E-6 T 13-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Astex_3509 542a87423ceff0873cc668dc5d9cc5dc 448 Pfam PF16499 Alpha galactosidase A 186 361 3.8E-23 T 13-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Astex_3509 542a87423ceff0873cc668dc5d9cc5dc 448 PRINTS PR00740 Glycosyl hydrolase family 27 signature 223 241 1.6E-13 T 13-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Astex_3509 542a87423ceff0873cc668dc5d9cc5dc 448 PRINTS PR00740 Glycosyl hydrolase family 27 signature 33 52 1.6E-13 T 13-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Astex_3509 542a87423ceff0873cc668dc5d9cc5dc 448 PRINTS PR00740 Glycosyl hydrolase family 27 signature 317 338 1.6E-13 T 13-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Astex_3509 542a87423ceff0873cc668dc5d9cc5dc 448 PRINTS PR00740 Glycosyl hydrolase family 27 signature 127 148 1.6E-13 T 13-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Astex_2807 09cf0209ac1cf7b14374c92c61e76438 221 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 25 169 1.8E-53 T 13-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2807 09cf0209ac1cf7b14374c92c61e76438 221 PIRSF PIRSF000216 4 221 2.5E-66 T 13-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2807 09cf0209ac1cf7b14374c92c61e76438 221 Gene3D G3DSA:3.40.30.10 91 188 2.1E-26 T 13-10-2018 Astex_2807 09cf0209ac1cf7b14374c92c61e76438 221 SUPERFAMILY SSF52833 16 189 9.17E-55 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Astex_2807 09cf0209ac1cf7b14374c92c61e76438 221 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 26 169 4.5E-55 T 13-10-2018 Astex_2807 09cf0209ac1cf7b14374c92c61e76438 221 Gene3D G3DSA:1.10.10.1590 14 87 3.7E-28 T 13-10-2018 Astex_3361 f3d2281ddfb5e67a45e7aeb6a4d75af9 229 SUPERFAMILY SSF52540 1 215 3.24E-30 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_3361 f3d2281ddfb5e67a45e7aeb6a4d75af9 229 PIRSF PIRSF009320 1 222 2.6E-40 T 13-10-2018 Astex_3361 f3d2281ddfb5e67a45e7aeb6a4d75af9 229 Pfam PF07015 VirC1 protein 1 185 6.0E-18 T 13-10-2018 IPR009744 VirC1 Astex_3361 f3d2281ddfb5e67a45e7aeb6a4d75af9 229 Gene3D G3DSA:3.40.50.300 1 215 6.0E-40 T 13-10-2018 Astex_0151 aab026384c1661107ce746a24905518b 196 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 196 24.653 T 13-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 Astex_0151 aab026384c1661107ce746a24905518b 196 Gene3D G3DSA:3.40.50.300 1 196 3.1E-58 T 13-10-2018 Astex_0151 aab026384c1661107ce746a24905518b 196 SUPERFAMILY SSF52540 3 193 9.52E-33 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0151 aab026384c1661107ce746a24905518b 196 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 5 187 4.7E-36 T 13-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 Astex_0151 aab026384c1661107ce746a24905518b 196 Pfam PF01121 Dephospho-CoA kinase 4 179 9.4E-39 T 13-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 Astex_1430 ab81a636dd859dd05d1c7f8780c595c0 212 Pfam PF13462 Thioredoxin 36 207 2.8E-32 T 13-10-2018 IPR012336 Thioredoxin-like fold Astex_1430 ab81a636dd859dd05d1c7f8780c595c0 212 SUPERFAMILY SSF52833 38 207 1.64E-31 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Astex_1430 ab81a636dd859dd05d1c7f8780c595c0 212 Gene3D G3DSA:3.40.30.10 29 212 5.8E-39 T 13-10-2018 Astex_3506 9acb5b38cfa5b4e9af67a7ef5effda08 367 Gene3D G3DSA:3.40.50.1820 121 365 4.1E-41 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_3506 9acb5b38cfa5b4e9af67a7ef5effda08 367 Pfam PF00756 Putative esterase 145 287 8.4E-17 T 13-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 Astex_3506 9acb5b38cfa5b4e9af67a7ef5effda08 367 SUPERFAMILY SSF53474 137 363 1.49E-29 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1327 7182f9f801f7bc3a84beaf58da99c9d2 354 Gene3D G3DSA:3.40.50.1100 55 161 8.0E-68 T 13-10-2018 Astex_1327 7182f9f801f7bc3a84beaf58da99c9d2 354 Gene3D G3DSA:3.40.50.1100 40 327 8.0E-68 T 13-10-2018 Astex_1327 7182f9f801f7bc3a84beaf58da99c9d2 354 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 36 320 2.8E-46 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme Astex_1327 7182f9f801f7bc3a84beaf58da99c9d2 354 SUPERFAMILY SSF53686 28 337 5.89E-70 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme Astex_1579 785ff6ba88ffab3b385bbb1154162b93 440 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 13 86 5.6E-17 T 13-10-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 Astex_1579 785ff6ba88ffab3b385bbb1154162b93 440 Pfam PF07670 Nucleoside recognition 106 203 9.4E-7 T 13-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 Astex_1579 785ff6ba88ffab3b385bbb1154162b93 440 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 213 420 7.9E-62 T 13-10-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 Astex_2240 631bc74e555a13c52a6a15c6e6b09e9b 250 Pfam PF07996 Type IV secretion system proteins 28 221 4.4E-52 T 13-10-2018 IPR014158 Type IV secretion system, VirB5 Astex_2240 631bc74e555a13c52a6a15c6e6b09e9b 250 SUPERFAMILY SSF101082 28 223 3.53E-30 T 13-10-2018 Astex_2240 631bc74e555a13c52a6a15c6e6b09e9b 250 Gene3D G3DSA:1.20.58.430 27 223 6.7E-34 T 13-10-2018 IPR023220 Type IV secretion system, VirB5-domain Astex_3458 9f4619dfc2786eabc3c55159ea4216c6 298 SUPERFAMILY SSF82861 33 120 6.93E-17 T 13-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 Astex_3458 9f4619dfc2786eabc3c55159ea4216c6 298 Gene3D G3DSA:2.30.30.60 137 185 6.9E-15 T 13-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily Astex_3458 9f4619dfc2786eabc3c55159ea4216c6 298 SUPERFAMILY SSF82689 190 282 1.44E-19 T 13-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 Astex_3458 9f4619dfc2786eabc3c55159ea4216c6 298 SUPERFAMILY SSF50182 122 187 2.58E-16 T 13-10-2018 IPR010920 LSM domain superfamily Astex_3458 9f4619dfc2786eabc3c55159ea4216c6 298 Pfam PF00924 Mechanosensitive ion channel 80 275 1.7E-48 T 13-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 Astex_3458 9f4619dfc2786eabc3c55159ea4216c6 298 Gene3D G3DSA:3.30.70.100 190 280 1.5E-17 T 13-10-2018 Astex_3458 9f4619dfc2786eabc3c55159ea4216c6 298 ProSitePatterns PS01246 Uncharacterized protein family UPF0003 signature. 151 185 - T 13-10-2018 IPR006686 Mechanosensitive ion channel MscS, conserved site GO:0016020 Astex_1644 565e7a3b9cf1637ce59aab0a9d4c3311 670 Pfam PF02780 Transketolase, C-terminal domain 554 657 2.7E-11 T 13-10-2018 IPR033248 Transketolase, C-terminal domain Astex_1644 565e7a3b9cf1637ce59aab0a9d4c3311 670 Gene3D G3DSA:3.40.50.970 16 331 7.9E-106 T 13-10-2018 Astex_1644 565e7a3b9cf1637ce59aab0a9d4c3311 670 ProSitePatterns PS00802 Transketolase signature 2. 472 488 - T 13-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 Astex_1644 565e7a3b9cf1637ce59aab0a9d4c3311 670 SUPERFAMILY SSF52922 539 665 5.57E-36 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Astex_1644 565e7a3b9cf1637ce59aab0a9d4c3311 670 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 18 330 2.2E-122 T 13-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 Astex_1644 565e7a3b9cf1637ce59aab0a9d4c3311 670 SMART SM00861 359 530 8.5E-66 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain Astex_1644 565e7a3b9cf1637ce59aab0a9d4c3311 670 TIGRFAM TIGR00232 tktlase_bact: transketolase 19 663 3.2E-236 T 13-10-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 Astex_1644 565e7a3b9cf1637ce59aab0a9d4c3311 670 Gene3D G3DSA:3.40.50.920 541 663 1.1E-36 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Astex_1644 565e7a3b9cf1637ce59aab0a9d4c3311 670 SUPERFAMILY SSF52518 18 326 3.07E-105 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold Astex_1644 565e7a3b9cf1637ce59aab0a9d4c3311 670 SUPERFAMILY SSF52518 346 530 9.74E-65 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold Astex_1644 565e7a3b9cf1637ce59aab0a9d4c3311 670 Pfam PF02779 Transketolase, pyrimidine binding domain 360 529 5.3E-45 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain Astex_1644 565e7a3b9cf1637ce59aab0a9d4c3311 670 Gene3D G3DSA:3.40.50.970 332 539 3.5E-75 T 13-10-2018 Astex_1759 bcb51e4de61f2dda125463f138f486a9 79 SMART SM01234 5 72 1.6E-30 T 13-10-2018 IPR002696 Putative membrane protein insertion efficiency factor Astex_1759 bcb51e4de61f2dda125463f138f486a9 79 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 5 73 19.786 T 13-10-2018 IPR002696 Putative membrane protein insertion efficiency factor Astex_1759 bcb51e4de61f2dda125463f138f486a9 79 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 13 78 8.4E-20 T 13-10-2018 IPR002696 Putative membrane protein insertion efficiency factor Astex_1759 bcb51e4de61f2dda125463f138f486a9 79 Pfam PF01809 Haemolytic domain 9 72 4.6E-23 T 13-10-2018 IPR002696 Putative membrane protein insertion efficiency factor Astex_1759 bcb51e4de61f2dda125463f138f486a9 79 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 20 71 7.0E-17 T 13-10-2018 IPR002696 Putative membrane protein insertion efficiency factor Astex_3284 5e4d2df036c53b1d8dd7a5f54e3816fc 296 Pfam PF02625 XdhC and CoxI family 23 90 2.8E-18 T 13-10-2018 IPR003777 XdhC- CoxI Astex_3284 5e4d2df036c53b1d8dd7a5f54e3816fc 296 Gene3D G3DSA:3.40.50.720 149 295 8.6E-34 T 13-10-2018 Astex_3284 5e4d2df036c53b1d8dd7a5f54e3816fc 296 Pfam PF13478 XdhC Rossmann domain 150 290 2.0E-32 T 13-10-2018 IPR027051 XdhC Rossmann domain Astex_0468 39e16a9da85577f2576702db7e276b5b 236 SUPERFAMILY SSF52172 1 125 2.56E-38 T 13-10-2018 IPR011006 CheY-like superfamily Astex_0468 39e16a9da85577f2576702db7e276b5b 236 Pfam PF00486 Transcriptional regulatory protein, C terminal 157 232 3.0E-21 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Astex_0468 39e16a9da85577f2576702db7e276b5b 236 SMART SM00448 2 112 1.7E-37 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_0468 39e16a9da85577f2576702db7e276b5b 236 Gene3D G3DSA:1.10.10.10 147 236 7.8E-27 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_0468 39e16a9da85577f2576702db7e276b5b 236 SUPERFAMILY SSF46894 139 233 1.67E-25 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Astex_0468 39e16a9da85577f2576702db7e276b5b 236 Pfam PF00072 Response regulator receiver domain 4 112 4.6E-25 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_0468 39e16a9da85577f2576702db7e276b5b 236 SMART SM00862 157 233 8.7E-19 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Astex_0468 39e16a9da85577f2576702db7e276b5b 236 Gene3D G3DSA:3.40.50.2300 2 146 6.5E-36 T 13-10-2018 Astex_2750 2135c2c951727f8936eab46e0b8c7f27 128 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 63 128 3.0E-22 T 13-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_2750 2135c2c951727f8936eab46e0b8c7f27 128 SUPERFAMILY SSF54736 56 128 1.48E-22 T 13-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like Astex_2750 2135c2c951727f8936eab46e0b8c7f27 128 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 3 50 5.1E-18 T 13-10-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_2750 2135c2c951727f8936eab46e0b8c7f27 128 SUPERFAMILY SSF48300 3 63 4.45E-15 T 13-10-2018 IPR036235 Ribosomal protein L7/L12, oligomerisation domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_2750 2135c2c951727f8936eab46e0b8c7f27 128 Gene3D G3DSA:1.20.5.710 3 56 5.2E-17 T 13-10-2018 Astex_2750 2135c2c951727f8936eab46e0b8c7f27 128 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 128 2.0E-43 T 13-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_2750 2135c2c951727f8936eab46e0b8c7f27 128 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 1 128 23.05 T 13-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_2750 2135c2c951727f8936eab46e0b8c7f27 128 Gene3D G3DSA:3.30.1390.10 57 128 9.1E-29 T 13-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like Astex_2750 2135c2c951727f8936eab46e0b8c7f27 128 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 61 128 6.2E-28 T 13-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_2533 5fc54cd7f936c385ded730fcb8fbbe72 317 Pfam PF02625 XdhC and CoxI family 14 69 3.5E-14 T 13-10-2018 IPR003777 XdhC- CoxI Astex_2533 5fc54cd7f936c385ded730fcb8fbbe72 317 TIGRFAM TIGR02964 xanthine_xdhC: xanthine dehydrogenase accessory protein XdhC 18 295 1.8E-74 T 13-10-2018 IPR014308 Xanthine dehydrogenase accessory protein XdhC Astex_2533 5fc54cd7f936c385ded730fcb8fbbe72 317 Pfam PF13478 XdhC Rossmann domain 160 294 1.8E-36 T 13-10-2018 IPR027051 XdhC Rossmann domain Astex_2533 5fc54cd7f936c385ded730fcb8fbbe72 317 Gene3D G3DSA:3.40.50.720 160 298 3.5E-34 T 13-10-2018 Astex_0746 2fa492560e127c8cac0a4a83aec46c15 381 SUPERFAMILY SSF53067 111 326 4.1E-43 T 13-10-2018 Astex_0746 2fa492560e127c8cac0a4a83aec46c15 381 Pfam PF00814 Glycoprotease family 29 324 2.2E-92 T 13-10-2018 IPR000905 Gcp-like domain Astex_0746 2fa492560e127c8cac0a4a83aec46c15 381 Gene3D G3DSA:3.30.420.40 137 311 5.3E-115 T 13-10-2018 Astex_0746 2fa492560e127c8cac0a4a83aec46c15 381 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 6 19 1.5E-45 T 13-10-2018 IPR017861 Kae1/TsaD family Astex_0746 2fa492560e127c8cac0a4a83aec46c15 381 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 139 151 1.5E-45 T 13-10-2018 IPR017861 Kae1/TsaD family Astex_0746 2fa492560e127c8cac0a4a83aec46c15 381 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 281 290 1.5E-45 T 13-10-2018 IPR017861 Kae1/TsaD family Astex_0746 2fa492560e127c8cac0a4a83aec46c15 381 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 162 183 1.5E-45 T 13-10-2018 IPR017861 Kae1/TsaD family Astex_0746 2fa492560e127c8cac0a4a83aec46c15 381 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 85 105 1.5E-45 T 13-10-2018 IPR017861 Kae1/TsaD family Astex_0746 2fa492560e127c8cac0a4a83aec46c15 381 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 106 125 1.5E-45 T 13-10-2018 IPR017861 Kae1/TsaD family Astex_0746 2fa492560e127c8cac0a4a83aec46c15 381 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 5 331 2.5E-119 T 13-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 Astex_0746 2fa492560e127c8cac0a4a83aec46c15 381 Gene3D G3DSA:3.30.420.40 5 332 5.3E-115 T 13-10-2018 Astex_0746 2fa492560e127c8cac0a4a83aec46c15 381 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 6 324 1.3E-93 T 13-10-2018 IPR017861 Kae1/TsaD family Astex_0746 2fa492560e127c8cac0a4a83aec46c15 381 SUPERFAMILY SSF53067 5 132 3.24E-26 T 13-10-2018 Astex_0746 2fa492560e127c8cac0a4a83aec46c15 381 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 3 360 61.616 T 13-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 Astex_3376 98cb3a86031e5467bc0a8a8bddc03e89 206 SUPERFAMILY SSF46689 12 92 4.24E-20 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Astex_3376 98cb3a86031e5467bc0a8a8bddc03e89 206 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 112 197 4.4E-7 T 13-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal Astex_3376 98cb3a86031e5467bc0a8a8bddc03e89 206 Gene3D G3DSA:1.10.357.10 9 205 7.8E-36 T 13-10-2018 Astex_3376 98cb3a86031e5467bc0a8a8bddc03e89 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 71 6.9E-16 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Astex_3376 98cb3a86031e5467bc0a8a8bddc03e89 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 9.3E-7 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Astex_3376 98cb3a86031e5467bc0a8a8bddc03e89 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 9.3E-7 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Astex_3266 074a7d31f68993ffff77d77d25644c36 253 Pfam PF00005 ABC transporter 43 190 1.2E-31 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_3266 074a7d31f68993ffff77d77d25644c36 253 Gene3D G3DSA:3.40.50.300 15 250 2.7E-54 T 13-10-2018 Astex_3266 074a7d31f68993ffff77d77d25644c36 253 SMART SM00382 52 239 2.4E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_3266 074a7d31f68993ffff77d77d25644c36 253 SUPERFAMILY SSF52540 36 246 1.56E-58 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_3266 074a7d31f68993ffff77d77d25644c36 253 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Astex_0143 73b028fbef381c1eede20f78c57278de 455 SMART SM00357 89 155 3.6E-16 T 13-10-2018 IPR011129 Cold shock domain GO:0003676 Astex_0143 73b028fbef381c1eede20f78c57278de 455 SMART SM00382 207 392 4.1E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_0143 73b028fbef381c1eede20f78c57278de 455 Gene3D G3DSA:1.10.720.10 36 83 6.1E-14 T 13-10-2018 Astex_0143 73b028fbef381c1eede20f78c57278de 455 Pfam PF07497 Rho termination factor, RNA-binding domain 89 162 5.6E-30 T 13-10-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 Astex_0143 73b028fbef381c1eede20f78c57278de 455 Gene3D G3DSA:3.40.50.300 167 454 1.6E-126 T 13-10-2018 Astex_0143 73b028fbef381c1eede20f78c57278de 455 TIGRFAM TIGR00767 rho: transcription termination factor Rho 40 454 6.7E-209 T 13-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 Astex_0143 73b028fbef381c1eede20f78c57278de 455 SUPERFAMILY SSF50249 86 162 6.85E-28 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Astex_0143 73b028fbef381c1eede20f78c57278de 455 Gene3D G3DSA:2.40.50.140 84 160 7.6E-32 T 13-10-2018 Astex_0143 73b028fbef381c1eede20f78c57278de 455 SUPERFAMILY SSF52540 128 408 2.3E-67 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0143 73b028fbef381c1eede20f78c57278de 455 Hamap MF_01884 Transcription termination factor Rho [rho]. 38 455 235.321 T 13-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 Astex_0143 73b028fbef381c1eede20f78c57278de 455 SMART SM00959 42 84 5.6E-14 T 13-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 Astex_0143 73b028fbef381c1eede20f78c57278de 455 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 197 400 1.4E-21 T 13-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Astex_0143 73b028fbef381c1eede20f78c57278de 455 Pfam PF07498 Rho termination factor, N-terminal domain 42 83 9.5E-14 T 13-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 Astex_0143 73b028fbef381c1eede20f78c57278de 455 SUPERFAMILY SSF68912 39 82 1.65E-9 T 13-10-2018 IPR036269 Rho termination factor, N-terminal domain superfamily Astex_2018 460d194881296f8f24f94ba7aae62b35 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 396 410 2.5E-8 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_2018 460d194881296f8f24f94ba7aae62b35 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 427 445 2.5E-8 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_2018 460d194881296f8f24f94ba7aae62b35 469 Gene3D G3DSA:3.30.565.10 321 467 1.3E-28 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_2018 460d194881296f8f24f94ba7aae62b35 469 Gene3D G3DSA:1.10.287.130 204 309 2.8E-6 T 13-10-2018 Astex_2018 460d194881296f8f24f94ba7aae62b35 469 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 362 463 5.8E-11 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_2018 460d194881296f8f24f94ba7aae62b35 469 SMART SM00387 359 467 1.2E-17 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_2018 460d194881296f8f24f94ba7aae62b35 469 SUPERFAMILY SSF55874 322 464 1.24E-26 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_2756 4dedcb7613ec6b7d1d1768bbe6928752 440 Pfam PF00579 tRNA synthetases class I (W and Y) 58 351 1.6E-71 T 13-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 Astex_2756 4dedcb7613ec6b7d1d1768bbe6928752 440 Gene3D G3DSA:1.10.240.10 253 359 6.4E-33 T 13-10-2018 Astex_2756 4dedcb7613ec6b7d1d1768bbe6928752 440 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 31 435 1.8E-105 T 13-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 Astex_2756 4dedcb7613ec6b7d1d1768bbe6928752 440 Gene3D G3DSA:3.40.50.620 6 252 1.0E-85 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Astex_2756 4dedcb7613ec6b7d1d1768bbe6928752 440 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 30 440 39.175 T 13-10-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 Astex_2756 4dedcb7613ec6b7d1d1768bbe6928752 440 SUPERFAMILY SSF52374 31 349 2.81E-95 T 13-10-2018 Astex_2756 4dedcb7613ec6b7d1d1768bbe6928752 440 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 213 235 1.7E-23 T 13-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 Astex_2756 4dedcb7613ec6b7d1d1768bbe6928752 440 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 246 258 1.7E-23 T 13-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 Astex_2756 4dedcb7613ec6b7d1d1768bbe6928752 440 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 192 207 1.7E-23 T 13-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 Astex_2756 4dedcb7613ec6b7d1d1768bbe6928752 440 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 72 94 1.7E-23 T 13-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 Astex_1493 d3b2f7d9cdbd7b1b997727ffd819c8cf 267 SUPERFAMILY SSF53218 7 202 1.57E-38 T 13-10-2018 IPR036425 MoaB/Mog-like domain superfamily Astex_1493 d3b2f7d9cdbd7b1b997727ffd819c8cf 267 Gene3D G3DSA:3.40.980.10 8 173 1.3E-49 T 13-10-2018 IPR036425 MoaB/Mog-like domain superfamily Astex_1493 d3b2f7d9cdbd7b1b997727ffd819c8cf 267 SMART SM00852 11 173 7.1E-30 T 13-10-2018 IPR001453 MoaB/Mog domain Astex_1493 d3b2f7d9cdbd7b1b997727ffd819c8cf 267 Pfam PF00994 Probable molybdopterin binding domain 11 171 1.7E-30 T 13-10-2018 IPR001453 MoaB/Mog domain Astex_0705 69b257de7fadb7f42d3adf75f07a6ab3 102 Pfam PF02325 YGGT family 12 86 4.6E-19 T 13-10-2018 IPR003425 CCB3/YggT GO:0016020 Astex_3194 ab8965f5f6a4b40f539a55ba1e135bf5 873 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 75 88 4.7E-34 T 13-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Astex_3194 ab8965f5f6a4b40f539a55ba1e135bf5 873 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 373 389 4.7E-34 T 13-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Astex_3194 ab8965f5f6a4b40f539a55ba1e135bf5 873 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 478 492 4.7E-34 T 13-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Astex_3194 ab8965f5f6a4b40f539a55ba1e135bf5 873 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 164 182 4.7E-34 T 13-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Astex_3194 ab8965f5f6a4b40f539a55ba1e135bf5 873 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 297 306 4.7E-34 T 13-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Astex_3194 ab8965f5f6a4b40f539a55ba1e135bf5 873 Gene3D G3DSA:2.70.20.10 186 462 1.2E-158 T 13-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 Astex_3194 ab8965f5f6a4b40f539a55ba1e135bf5 873 SMART SM00436 106 194 5.8E-42 T 13-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 Astex_3194 ab8965f5f6a4b40f539a55ba1e135bf5 873 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 284 306 - T 13-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 Astex_3194 ab8965f5f6a4b40f539a55ba1e135bf5 873 Gene3D G3DSA:1.10.290.10 255 388 1.2E-158 T 13-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 Astex_3194 ab8965f5f6a4b40f539a55ba1e135bf5 873 Gene3D G3DSA:3.40.50.140 1 136 8.5E-50 T 13-10-2018 Astex_3194 ab8965f5f6a4b40f539a55ba1e135bf5 873 Gene3D G3DSA:1.10.460.10 140 555 1.2E-158 T 13-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 Astex_3194 ab8965f5f6a4b40f539a55ba1e135bf5 873 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 3 631 3.1E-234 T 13-10-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 Astex_3194 ab8965f5f6a4b40f539a55ba1e135bf5 873 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 598 632 4.5E-15 T 13-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 Astex_3194 ab8965f5f6a4b40f539a55ba1e135bf5 873 SUPERFAMILY SSF56712 1 606 4.97E-184 T 13-10-2018 IPR023405 DNA topoisomerase, type IA, core domain Astex_3194 ab8965f5f6a4b40f539a55ba1e135bf5 873 Hamap MF_00952 DNA topoisomerase 1 [topA]. 1 736 54.481 T 13-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 Astex_3194 ab8965f5f6a4b40f539a55ba1e135bf5 873 SUPERFAMILY SSF57783 597 636 9.52E-9 T 13-10-2018 Astex_3194 ab8965f5f6a4b40f539a55ba1e135bf5 873 Pfam PF01751 Toprim domain 3 115 2.2E-25 T 13-10-2018 IPR006171 TOPRIM domain Astex_3194 ab8965f5f6a4b40f539a55ba1e135bf5 873 SMART SM00437 247 515 1.1E-115 T 13-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 Astex_3194 ab8965f5f6a4b40f539a55ba1e135bf5 873 Pfam PF01131 DNA topoisomerase 130 552 2.4E-125 T 13-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 Astex_3194 ab8965f5f6a4b40f539a55ba1e135bf5 873 Gene3D G3DSA:3.30.65.10 595 638 5.1E-5 T 13-10-2018 Astex_3194 ab8965f5f6a4b40f539a55ba1e135bf5 873 SMART SM00493 1 101 5.0E-28 T 13-10-2018 IPR006171 TOPRIM domain Astex_3194 ab8965f5f6a4b40f539a55ba1e135bf5 873 Pfam PF13368 Topoisomerase C-terminal repeat 653 712 3.3E-15 T 13-10-2018 IPR025589 Topoisomerase C-terminal repeat Astex_3194 ab8965f5f6a4b40f539a55ba1e135bf5 873 Pfam PF13368 Topoisomerase C-terminal repeat 783 832 2.5E-20 T 13-10-2018 IPR025589 Topoisomerase C-terminal repeat Astex_3194 ab8965f5f6a4b40f539a55ba1e135bf5 873 Pfam PF13368 Topoisomerase C-terminal repeat 715 769 6.0E-20 T 13-10-2018 IPR025589 Topoisomerase C-terminal repeat Astex_3694 9b9a5899f96d40482ff758d724788993 928 Pfam PF07715 TonB-dependent Receptor Plug Domain 59 176 8.4E-20 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_3694 9b9a5899f96d40482ff758d724788993 928 SUPERFAMILY SSF56935 46 928 2.38E-78 T 13-10-2018 Astex_3694 9b9a5899f96d40482ff758d724788993 928 Pfam PF00593 TonB dependent receptor 461 900 1.4E-32 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_3694 9b9a5899f96d40482ff758d724788993 928 Gene3D G3DSA:2.170.130.10 45 179 2.2E-17 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_3694 9b9a5899f96d40482ff758d724788993 928 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 39 928 5.7E-163 T 13-10-2018 IPR010104 Bacterial TonB-dependent receptor Astex_0019 dbaabe189ac13313c5ff7825c89977ac 534 Gene3D G3DSA:3.40.50.1380 11 210 5.6E-79 T 13-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily Astex_0019 dbaabe189ac13313c5ff7825c89977ac 534 Gene3D G3DSA:3.40.140.20 216 367 3.6E-61 T 13-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Astex_0019 dbaabe189ac13313c5ff7825c89977ac 534 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 16 534 42.574 T 13-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Astex_0019 dbaabe189ac13313c5ff7825c89977ac 534 SUPERFAMILY SSF53927 221 534 3.71E-127 T 13-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 Astex_0019 dbaabe189ac13313c5ff7825c89977ac 534 SMART SM00851 28 142 5.7E-45 T 13-10-2018 IPR011607 Methylglyoxal synthase-like domain Astex_0019 dbaabe189ac13313c5ff7825c89977ac 534 PIRSF PIRSF000414 12 534 1.3E-201 T 13-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Astex_0019 dbaabe189ac13313c5ff7825c89977ac 534 SMART SM00798 147 459 4.7E-195 T 13-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Astex_0019 dbaabe189ac13313c5ff7825c89977ac 534 Gene3D G3DSA:3.40.140.20 391 534 7.8E-51 T 13-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Astex_0019 dbaabe189ac13313c5ff7825c89977ac 534 Pfam PF01808 AICARFT/IMPCHase bienzyme 148 456 1.0E-116 T 13-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Astex_0019 dbaabe189ac13313c5ff7825c89977ac 534 Pfam PF02142 MGS-like domain 28 141 4.4E-22 T 13-10-2018 IPR011607 Methylglyoxal synthase-like domain Astex_0019 dbaabe189ac13313c5ff7825c89977ac 534 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 17 534 7.3E-203 T 13-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Astex_0019 dbaabe189ac13313c5ff7825c89977ac 534 SUPERFAMILY SSF52335 17 206 1.97E-59 T 13-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily Astex_0600 8fcdbd792c0050d2515d5ea829fb6170 165 Pfam PF14081 Domain of unknown function (DUF4262) 23 143 1.4E-34 T 13-10-2018 IPR025358 Protein of unknown function DUF4262 Astex_0044 e2e21783f827c0415d69ff8082b9f3ad 283 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 15 233 35.483 T 13-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 Astex_0044 e2e21783f827c0415d69ff8082b9f3ad 283 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 16 214 8.4E-29 T 13-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 Astex_0044 e2e21783f827c0415d69ff8082b9f3ad 283 PIRSF PIRSF005917 6 283 1.1E-92 T 13-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 Astex_0044 e2e21783f827c0415d69ff8082b9f3ad 283 Gene3D G3DSA:3.30.950.10 123 237 6.1E-36 T 13-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 Astex_0044 e2e21783f827c0415d69ff8082b9f3ad 283 Gene3D G3DSA:3.40.1010.10 6 122 6.1E-42 T 13-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 Astex_0044 e2e21783f827c0415d69ff8082b9f3ad 283 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 93 104 - T 13-10-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 Astex_0044 e2e21783f827c0415d69ff8082b9f3ad 283 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 16 280 2.7E-72 T 13-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 Astex_0044 e2e21783f827c0415d69ff8082b9f3ad 283 SUPERFAMILY SSF53790 14 231 1.57E-75 T 13-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 Astex_3271 62a4eab8bdda5c3641fc49138d71124f 929 SUPERFAMILY SSF55073 508 657 3.69E-43 T 13-10-2018 IPR029787 Nucleotide cyclase Astex_3271 62a4eab8bdda5c3641fc49138d71124f 929 Gene3D G3DSA:3.20.20.450 678 925 3.0E-95 T 13-10-2018 IPR035919 EAL domain superfamily Astex_3271 62a4eab8bdda5c3641fc49138d71124f 929 SMART SM00267 492 666 2.4E-52 T 13-10-2018 IPR000160 GGDEF domain Astex_3271 62a4eab8bdda5c3641fc49138d71124f 929 Pfam PF03707 Bacterial signalling protein N terminal repeat 58 112 1.7E-12 T 13-10-2018 IPR005330 MHYT domain Astex_3271 62a4eab8bdda5c3641fc49138d71124f 929 Pfam PF03707 Bacterial signalling protein N terminal repeat 120 170 2.1E-11 T 13-10-2018 IPR005330 MHYT domain Astex_3271 62a4eab8bdda5c3641fc49138d71124f 929 Pfam PF00989 PAS fold 254 362 2.1E-15 T 13-10-2018 IPR013767 PAS fold GO:0006355 Astex_3271 62a4eab8bdda5c3641fc49138d71124f 929 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 500 657 7.5E-37 T 13-10-2018 IPR000160 GGDEF domain Astex_3271 62a4eab8bdda5c3641fc49138d71124f 929 SMART SM00052 677 919 1.3E-108 T 13-10-2018 IPR001633 EAL domain Astex_3271 62a4eab8bdda5c3641fc49138d71124f 929 Pfam PF12860 PAS fold 383 496 7.7E-27 T 13-10-2018 Astex_3271 62a4eab8bdda5c3641fc49138d71124f 929 Gene3D G3DSA:3.30.450.20 258 368 1.3E-24 T 13-10-2018 Astex_3271 62a4eab8bdda5c3641fc49138d71124f 929 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 247 368 3.8E-19 T 13-10-2018 IPR000014 PAS domain Astex_3271 62a4eab8bdda5c3641fc49138d71124f 929 Pfam PF00563 EAL domain 684 914 2.6E-73 T 13-10-2018 IPR001633 EAL domain Astex_3271 62a4eab8bdda5c3641fc49138d71124f 929 Pfam PF00990 Diguanylate cyclase, GGDEF domain 503 657 1.4E-41 T 13-10-2018 IPR000160 GGDEF domain Astex_3271 62a4eab8bdda5c3641fc49138d71124f 929 Gene3D G3DSA:3.30.70.270 498 667 6.6E-50 T 13-10-2018 Astex_3271 62a4eab8bdda5c3641fc49138d71124f 929 SUPERFAMILY SSF55785 362 490 9.25E-9 T 13-10-2018 IPR035965 PAS domain superfamily Astex_3271 62a4eab8bdda5c3641fc49138d71124f 929 SUPERFAMILY SSF55785 235 363 3.49E-25 T 13-10-2018 IPR035965 PAS domain superfamily Astex_3271 62a4eab8bdda5c3641fc49138d71124f 929 SUPERFAMILY SSF141868 683 915 1.11E-87 T 13-10-2018 IPR035919 EAL domain superfamily Astex_3271 62a4eab8bdda5c3641fc49138d71124f 929 SMART SM00091 377 443 4.0 T 13-10-2018 IPR000014 PAS domain Astex_3271 62a4eab8bdda5c3641fc49138d71124f 929 SMART SM00091 249 318 1.9E-5 T 13-10-2018 IPR000014 PAS domain Astex_3271 62a4eab8bdda5c3641fc49138d71124f 929 Gene3D G3DSA:3.30.450.20 369 497 1.7E-9 T 13-10-2018 Astex_0246 4afd1c0b5fe0875d52bae743dfaece68 459 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 6 439 1.6E-85 T 13-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G Astex_0246 4afd1c0b5fe0875d52bae743dfaece68 459 Pfam PF00460 Flagella basal body rod protein 7 37 8.6E-9 T 13-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 Astex_0246 4afd1c0b5fe0875d52bae743dfaece68 459 SUPERFAMILY SSF117143 80 419 8.11E-66 T 13-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like Astex_0246 4afd1c0b5fe0875d52bae743dfaece68 459 Pfam PF07559 Flagellar basal body protein FlaE 209 338 1.3E-13 T 13-10-2018 IPR011491 Flagellar hook protein FlgE Astex_0246 4afd1c0b5fe0875d52bae743dfaece68 459 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 13 33 - T 13-10-2018 IPR019776 Flagellar basal body rod protein, conserved site Astex_0246 4afd1c0b5fe0875d52bae743dfaece68 459 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 379 455 6.7E-17 T 13-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain Astex_1929 4f5b3524a024f1215796cd2f71c1b2d5 788 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 28 173 6.9E-18 T 13-10-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_1929 4f5b3524a024f1215796cd2f71c1b2d5 788 Gene3D G3DSA:2.60.40.10 679 788 4.6E-31 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_1929 4f5b3524a024f1215796cd2f71c1b2d5 788 Gene3D G3DSA:2.60.40.10 177 291 9.5E-24 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_1929 4f5b3524a024f1215796cd2f71c1b2d5 788 Pfam PF00703 Glycosyl hydrolases family 2 180 291 1.4E-13 T 13-10-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_1929 4f5b3524a024f1215796cd2f71c1b2d5 788 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 298 453 6.4E-28 T 13-10-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 Astex_1929 4f5b3524a024f1215796cd2f71c1b2d5 788 Gene3D G3DSA:3.20.20.80 293 566 5.9E-81 T 13-10-2018 Astex_1929 4f5b3524a024f1215796cd2f71c1b2d5 788 ProSitePatterns PS00608 Glycosyl hydrolases family 2 acid/base catalyst. 404 418 - T 13-10-2018 IPR023232 Glycoside hydrolase, family 2, active site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_1929 4f5b3524a024f1215796cd2f71c1b2d5 788 PRINTS PR00132 Glycosyl hydrolase family 2 signature 404 419 2.3E-12 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_1929 4f5b3524a024f1215796cd2f71c1b2d5 788 PRINTS PR00132 Glycosyl hydrolase family 2 signature 334 352 2.3E-12 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_1929 4f5b3524a024f1215796cd2f71c1b2d5 788 PRINTS PR00132 Glycosyl hydrolase family 2 signature 108 123 2.3E-12 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_1929 4f5b3524a024f1215796cd2f71c1b2d5 788 PRINTS PR00132 Glycosyl hydrolase family 2 signature 303 317 2.3E-12 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_1929 4f5b3524a024f1215796cd2f71c1b2d5 788 SUPERFAMILY SSF49303 183 291 3.17E-15 T 13-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily Astex_1929 4f5b3524a024f1215796cd2f71c1b2d5 788 SUPERFAMILY SSF49785 9 176 5.35E-41 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_1929 4f5b3524a024f1215796cd2f71c1b2d5 788 Gene3D G3DSA:2.60.40.10 597 676 3.0E-16 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_1929 4f5b3524a024f1215796cd2f71c1b2d5 788 Gene3D G3DSA:2.60.120.260 19 176 1.1E-48 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_1929 4f5b3524a024f1215796cd2f71c1b2d5 788 Pfam PF16355 Domain of unknown function (DUF4982) 613 670 1.9E-17 T 13-10-2018 IPR032311 Domain of unknown function DUF4982 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_1929 4f5b3524a024f1215796cd2f71c1b2d5 788 SUPERFAMILY SSF51445 288 561 1.2E-60 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_1302 270e3910efc96b0b6ad9419084458be2 509 SUPERFAMILY SSF48452 17 215 1.99E-16 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_1302 270e3910efc96b0b6ad9419084458be2 509 Gene3D G3DSA:1.25.40.10 1 91 1.0E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_1302 270e3910efc96b0b6ad9419084458be2 509 SUPERFAMILY SSF52540 260 488 4.87E-43 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1302 270e3910efc96b0b6ad9419084458be2 509 Pfam PF13469 Sulfotransferase family 265 452 5.3E-37 T 13-10-2018 Astex_1302 270e3910efc96b0b6ad9419084458be2 509 Pfam PF13181 Tetratricopeptide repeat 123 152 6.2E-6 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Astex_1302 270e3910efc96b0b6ad9419084458be2 509 Gene3D G3DSA:1.25.40.10 92 182 1.7E-13 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_1302 270e3910efc96b0b6ad9419084458be2 509 SMART SM00028 19 52 250.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Astex_1302 270e3910efc96b0b6ad9419084458be2 509 SMART SM00028 122 155 7.9E-4 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Astex_1302 270e3910efc96b0b6ad9419084458be2 509 Gene3D G3DSA:3.40.50.300 254 508 4.9E-52 T 13-10-2018 Astex_2962 23c01ddcbdac091f0aa4ce811f92dce3 271 ProSitePatterns PS00761 Signal peptidases I signature 3. 202 215 - T 13-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 Astex_2962 23c01ddcbdac091f0aa4ce811f92dce3 271 Gene3D G3DSA:2.170.230.10 131 196 4.6E-57 T 13-10-2018 Astex_2962 23c01ddcbdac091f0aa4ce811f92dce3 271 Gene3D G3DSA:2.10.109.10 48 246 4.6E-57 T 13-10-2018 Astex_2962 23c01ddcbdac091f0aa4ce811f92dce3 271 SUPERFAMILY SSF51306 48 269 6.1E-61 T 13-10-2018 IPR036286 LexA/Signal peptidase-like superfamily Astex_2962 23c01ddcbdac091f0aa4ce811f92dce3 271 Pfam PF00717 Peptidase S24-like 56 143 6.8E-21 T 13-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C Astex_2962 23c01ddcbdac091f0aa4ce811f92dce3 271 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 34 246 6.1E-50 T 13-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 Astex_2962 23c01ddcbdac091f0aa4ce811f92dce3 271 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 120 132 4.1E-24 T 13-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 Astex_2962 23c01ddcbdac091f0aa4ce811f92dce3 271 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 197 216 4.1E-24 T 13-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 Astex_2962 23c01ddcbdac091f0aa4ce811f92dce3 271 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 50 66 4.1E-24 T 13-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 Astex_2962 23c01ddcbdac091f0aa4ce811f92dce3 271 ProSitePatterns PS00760 Signal peptidases I lysine active site. 122 134 - T 13-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 Astex_3109 7d23b04acd5bacd3015cbd6a04e9e679 276 Gene3D G3DSA:2.170.280.10 176 189 7.8E-24 T 13-10-2018 Astex_3109 7d23b04acd5bacd3015cbd6a04e9e679 276 Gene3D G3DSA:1.20.58.1830 6 34 7.8E-24 T 13-10-2018 Astex_3109 7d23b04acd5bacd3015cbd6a04e9e679 276 SUPERFAMILY SSF64518 1 276 7.59E-57 T 13-10-2018 Astex_3109 7d23b04acd5bacd3015cbd6a04e9e679 276 PRINTS PR00207 Flagellin signature 112 135 1.0E-5 T 13-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 Astex_3109 7d23b04acd5bacd3015cbd6a04e9e679 276 PRINTS PR00207 Flagellin signature 38 55 1.0E-5 T 13-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 Astex_3109 7d23b04acd5bacd3015cbd6a04e9e679 276 PRINTS PR00207 Flagellin signature 77 96 1.0E-5 T 13-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 Astex_3109 7d23b04acd5bacd3015cbd6a04e9e679 276 Pfam PF00700 Bacterial flagellin C-terminal helical region 191 274 3.3E-12 T 13-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 Astex_3109 7d23b04acd5bacd3015cbd6a04e9e679 276 Gene3D G3DSA:1.10.8.410 226 276 2.3E-5 T 13-10-2018 Astex_3109 7d23b04acd5bacd3015cbd6a04e9e679 276 Gene3D G3DSA:1.20.1330.10 46 175 7.8E-24 T 13-10-2018 Astex_3109 7d23b04acd5bacd3015cbd6a04e9e679 276 Pfam PF00669 Bacterial flagellin N-terminal helical region 6 140 6.6E-27 T 13-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 Astex_3109 7d23b04acd5bacd3015cbd6a04e9e679 276 Gene3D G3DSA:2.30.220.10 190 216 7.8E-24 T 13-10-2018 Astex_1416 bf23955991577c6e9685ab5491d0155b 355 TIGRFAM TIGR00328 flhB: flagellar biosynthetic protein FlhB 6 351 5.1E-116 T 13-10-2018 IPR006136 Flagellar biosynthetic protein FlhB GO:0015031|GO:0016021|GO:0044780 Astex_1416 bf23955991577c6e9685ab5491d0155b 355 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 302 323 4.6E-37 T 13-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 Astex_1416 bf23955991577c6e9685ab5491d0155b 355 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 9 31 4.6E-37 T 13-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 Astex_1416 bf23955991577c6e9685ab5491d0155b 355 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 229 246 4.6E-37 T 13-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 Astex_1416 bf23955991577c6e9685ab5491d0155b 355 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 209 227 4.6E-37 T 13-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 Astex_1416 bf23955991577c6e9685ab5491d0155b 355 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 273 288 4.6E-37 T 13-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 Astex_1416 bf23955991577c6e9685ab5491d0155b 355 Gene3D G3DSA:3.40.1690.10 219 354 1.3E-54 T 13-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal Astex_1416 bf23955991577c6e9685ab5491d0155b 355 SUPERFAMILY SSF160544 246 349 7.32E-38 T 13-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal Astex_1416 bf23955991577c6e9685ab5491d0155b 355 Pfam PF01312 FlhB HrpN YscU SpaS Family 6 347 2.6E-121 T 13-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 Astex_2884 2a5d1bf80bb603c80ea037e13a7c7377 1168 Gene3D G3DSA:3.30.2060.10 130 216 1.3E-85 T 13-10-2018 Astex_2884 2a5d1bf80bb603c80ea037e13a7c7377 1168 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 149 1097 0.0 T 13-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 Astex_2884 2a5d1bf80bb603c80ea037e13a7c7377 1168 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 13 1164 27.412 T 13-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 Astex_2884 2a5d1bf80bb603c80ea037e13a7c7377 1168 Gene3D G3DSA:3.40.50.300 497 1006 1.4E-221 T 13-10-2018 Astex_2884 2a5d1bf80bb603c80ea037e13a7c7377 1168 SMART SM01058 497 593 4.4E-41 T 13-10-2018 IPR003711 CarD-like/TRCF domain Astex_2884 2a5d1bf80bb603c80ea037e13a7c7377 1168 SMART SM00982 1025 1125 6.8E-40 T 13-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 Astex_2884 2a5d1bf80bb603c80ea037e13a7c7377 1168 SMART SM00487 617 807 2.7E-32 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Astex_2884 2a5d1bf80bb603c80ea037e13a7c7377 1168 SUPERFAMILY SSF52540 799 1007 1.64E-44 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2884 2a5d1bf80bb603c80ea037e13a7c7377 1168 Pfam PF03461 TRCF domain 1030 1117 2.6E-24 T 13-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 Astex_2884 2a5d1bf80bb603c80ea037e13a7c7377 1168 SUPERFAMILY SSF52540 541 801 2.6E-57 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2884 2a5d1bf80bb603c80ea037e13a7c7377 1168 SUPERFAMILY SSF52540 5 358 1.73E-82 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2884 2a5d1bf80bb603c80ea037e13a7c7377 1168 Pfam PF00270 DEAD/DEAH box helicase 622 783 2.5E-15 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Astex_2884 2a5d1bf80bb603c80ea037e13a7c7377 1168 Pfam PF02559 CarD-like/TRCF domain 498 591 1.1E-24 T 13-10-2018 IPR003711 CarD-like/TRCF domain Astex_2884 2a5d1bf80bb603c80ea037e13a7c7377 1168 SUPERFAMILY SSF143517 1019 1163 4.58E-39 T 13-10-2018 IPR037235 TRCF-like, C-terminal domain Astex_2884 2a5d1bf80bb603c80ea037e13a7c7377 1168 Gene3D G3DSA:3.40.50.11180 38 311 1.3E-85 T 13-10-2018 Astex_2884 2a5d1bf80bb603c80ea037e13a7c7377 1168 SMART SM00490 843 927 3.9E-19 T 13-10-2018 IPR001650 Helicase, C-terminal Astex_2884 2a5d1bf80bb603c80ea037e13a7c7377 1168 Gene3D G3DSA:2.30.30.840 501 558 1.4E-221 T 13-10-2018 Astex_2884 2a5d1bf80bb603c80ea037e13a7c7377 1168 Gene3D G3DSA:3.40.50.300 559 798 1.4E-221 T 13-10-2018 Astex_2884 2a5d1bf80bb603c80ea037e13a7c7377 1168 Gene3D G3DSA:3.90.1150.50 1022 1166 7.2E-36 T 13-10-2018 IPR037235 TRCF-like, C-terminal domain Astex_2884 2a5d1bf80bb603c80ea037e13a7c7377 1168 Pfam PF00271 Helicase conserved C-terminal domain 820 926 2.0E-17 T 13-10-2018 IPR001650 Helicase, C-terminal Astex_2884 2a5d1bf80bb603c80ea037e13a7c7377 1168 SUPERFAMILY SSF52540 364 488 1.7E-20 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2884 2a5d1bf80bb603c80ea037e13a7c7377 1168 SUPERFAMILY SSF141259 489 565 9.42E-20 T 13-10-2018 IPR036101 CarD-like/TRCF domain superfamily Astex_3053 11939be0cf5a1a03f240822c492c7b5e 464 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 162 175 1.0E-8 T 13-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 Astex_3053 11939be0cf5a1a03f240822c492c7b5e 464 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 82 93 1.0E-8 T 13-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 Astex_3053 11939be0cf5a1a03f240822c492c7b5e 464 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 135 152 1.0E-8 T 13-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 Astex_3053 11939be0cf5a1a03f240822c492c7b5e 464 SUPERFAMILY SSF110997 387 463 8.24E-5 T 13-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 Astex_3053 11939be0cf5a1a03f240822c492c7b5e 464 SUPERFAMILY SSF56601 29 292 2.68E-75 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like Astex_3053 11939be0cf5a1a03f240822c492c7b5e 464 Gene3D G3DSA:3.40.710.10 28 321 2.6E-82 T 13-10-2018 Astex_3053 11939be0cf5a1a03f240822c492c7b5e 464 Pfam PF05036 Sporulation related domain 390 463 1.3E-10 T 13-10-2018 IPR007730 Sporulation-like domain GO:0042834 Astex_3053 11939be0cf5a1a03f240822c492c7b5e 464 Gene3D G3DSA:3.30.70.1070 389 464 7.0E-5 T 13-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 Astex_3053 11939be0cf5a1a03f240822c492c7b5e 464 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 49 274 1.6E-58 T 13-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 Astex_3316 119c67dc4e290ffa338a26cec2a43a05 693 Pfam PF06964 Alpha-L-arabinofuranosidase C-terminal domain 503 669 2.6E-5 T 13-10-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 Astex_3316 119c67dc4e290ffa338a26cec2a43a05 693 SUPERFAMILY SSF51445 209 550 1.74E-64 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_3316 119c67dc4e290ffa338a26cec2a43a05 693 Gene3D G3DSA:2.60.40.1180 565 690 2.7E-13 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta Astex_3316 119c67dc4e290ffa338a26cec2a43a05 693 SMART SM00813 503 684 5.5E-14 T 13-10-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 Astex_3316 119c67dc4e290ffa338a26cec2a43a05 693 Gene3D G3DSA:3.20.20.80 216 564 7.9E-87 T 13-10-2018 Astex_3316 119c67dc4e290ffa338a26cec2a43a05 693 SUPERFAMILY SSF51011 600 670 5.76E-6 T 13-10-2018 Astex_1277 bc2c6910157a52f6a19438f25ed7b3ca 1074 Gene3D G3DSA:3.30.2090.10 181 277 0.0 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Astex_1277 bc2c6910157a52f6a19438f25ed7b3ca 1074 SUPERFAMILY SSF82714 185 273 3.14E-20 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Astex_1277 bc2c6910157a52f6a19438f25ed7b3ca 1074 Pfam PF00873 AcrB/AcrD/AcrF family 4 1035 0.0 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_1277 bc2c6910157a52f6a19438f25ed7b3ca 1074 SUPERFAMILY SSF82693 574 680 3.66E-23 T 13-10-2018 Astex_1277 bc2c6910157a52f6a19438f25ed7b3ca 1074 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 3 1055 0.0 T 13-10-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0006855|GO:0015562|GO:0016021 Astex_1277 bc2c6910157a52f6a19438f25ed7b3ca 1074 Gene3D G3DSA:3.30.70.1440 678 875 0.0 T 13-10-2018 Astex_1277 bc2c6910157a52f6a19438f25ed7b3ca 1074 Gene3D G3DSA:3.30.2090.10 730 818 0.0 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Astex_1277 bc2c6910157a52f6a19438f25ed7b3ca 1074 SUPERFAMILY SSF82693 41 133 5.75E-26 T 13-10-2018 Astex_1277 bc2c6910157a52f6a19438f25ed7b3ca 1074 Gene3D G3DSA:1.20.1640.10 522 1032 0.0 T 13-10-2018 Astex_1277 bc2c6910157a52f6a19438f25ed7b3ca 1074 SUPERFAMILY SSF82866 841 1035 1.83E-44 T 13-10-2018 Astex_1277 bc2c6910157a52f6a19438f25ed7b3ca 1074 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.7E-91 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_1277 bc2c6910157a52f6a19438f25ed7b3ca 1074 PRINTS PR00702 Acriflavin resistance protein family signature 446 469 1.7E-91 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_1277 bc2c6910157a52f6a19438f25ed7b3ca 1074 PRINTS PR00702 Acriflavin resistance protein family signature 630 644 1.7E-91 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_1277 bc2c6910157a52f6a19438f25ed7b3ca 1074 PRINTS PR00702 Acriflavin resistance protein family signature 338 361 1.7E-91 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_1277 bc2c6910157a52f6a19438f25ed7b3ca 1074 PRINTS PR00702 Acriflavin resistance protein family signature 365 386 1.7E-91 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_1277 bc2c6910157a52f6a19438f25ed7b3ca 1074 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.7E-91 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_1277 bc2c6910157a52f6a19438f25ed7b3ca 1074 PRINTS PR00702 Acriflavin resistance protein family signature 393 417 1.7E-91 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_1277 bc2c6910157a52f6a19438f25ed7b3ca 1074 PRINTS PR00702 Acriflavin resistance protein family signature 471 494 1.7E-91 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_1277 bc2c6910157a52f6a19438f25ed7b3ca 1074 PRINTS PR00702 Acriflavin resistance protein family signature 561 578 1.7E-91 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_1277 bc2c6910157a52f6a19438f25ed7b3ca 1074 Gene3D G3DSA:3.30.70.1320 135 334 0.0 T 13-10-2018 Astex_1277 bc2c6910157a52f6a19438f25ed7b3ca 1074 Gene3D G3DSA:3.30.70.1430 576 677 0.0 T 13-10-2018 Astex_1277 bc2c6910157a52f6a19438f25ed7b3ca 1074 SUPERFAMILY SSF82693 140 332 6.28E-26 T 13-10-2018 Astex_1277 bc2c6910157a52f6a19438f25ed7b3ca 1074 Gene3D G3DSA:3.30.70.1430 40 826 0.0 T 13-10-2018 Astex_1277 bc2c6910157a52f6a19438f25ed7b3ca 1074 Gene3D G3DSA:1.20.1640.10 10 521 0.0 T 13-10-2018 Astex_1277 bc2c6910157a52f6a19438f25ed7b3ca 1074 SUPERFAMILY SSF82693 681 866 4.71E-27 T 13-10-2018 Astex_1277 bc2c6910157a52f6a19438f25ed7b3ca 1074 SUPERFAMILY SSF82866 298 498 3.4E-55 T 13-10-2018 Astex_1277 bc2c6910157a52f6a19438f25ed7b3ca 1074 SUPERFAMILY SSF82714 731 817 2.35E-22 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Astex_1309 263e0d5394580bd08b258009a0579ae4 1023 Pfam PF00171 Aldehyde dehydrogenase family 549 1002 1.1E-111 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 Astex_1309 263e0d5394580bd08b258009a0579ae4 1023 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 807 818 - T 13-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 Astex_1309 263e0d5394580bd08b258009a0579ae4 1023 Gene3D G3DSA:3.40.605.10 523 1002 5.7E-153 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 Astex_1309 263e0d5394580bd08b258009a0579ae4 1023 SUPERFAMILY SSF51730 170 503 1.41E-102 T 13-10-2018 IPR029041 FAD-linked oxidoreductase-like Astex_1309 263e0d5394580bd08b258009a0579ae4 1023 SUPERFAMILY SSF81935 6 169 1.7E-46 T 13-10-2018 IPR024089 Proline dehydrogenase PutA, domain I/II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 Astex_1309 263e0d5394580bd08b258009a0579ae4 1023 PIRSF PIRSF000197 2 1020 0.0 T 13-10-2018 IPR025703 Bifunctional protein PutA GO:0003700|GO:0003842|GO:0004657|GO:0006355|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 Astex_1309 263e0d5394580bd08b258009a0579ae4 1023 TIGRFAM TIGR01238 D1pyr5carbox3: delta-1-pyrroline-5-carboxylate dehydrogenase 503 999 1.6E-195 T 13-10-2018 IPR005933 Delta-1-pyrroline-5-carboxylate dehydrogenase 3 GO:0003842|GO:0006561|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 Astex_1309 263e0d5394580bd08b258009a0579ae4 1023 Gene3D G3DSA:3.40.309.10 782 969 5.7E-153 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 Astex_1309 263e0d5394580bd08b258009a0579ae4 1023 Pfam PF14850 DNA-binding domain of Proline dehydrogenase 59 167 6.0E-37 T 13-10-2018 IPR024082 Proline dehydrogenase PutA, domain II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 Astex_1309 263e0d5394580bd08b258009a0579ae4 1023 SUPERFAMILY SSF53720 531 1004 5.5E-127 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 Astex_1309 263e0d5394580bd08b258009a0579ae4 1023 Pfam PF01619 Proline dehydrogenase 180 464 1.1E-83 T 13-10-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 Astex_1309 263e0d5394580bd08b258009a0579ae4 1023 Gene3D G3DSA:3.20.20.220 108 499 9.5E-125 T 13-10-2018 Astex_2222 69e5f1cb7f6d3b043ec3728bf1e06543 303 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 106 294 5.4E-16 T 13-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase Astex_2222 69e5f1cb7f6d3b043ec3728bf1e06543 303 SUPERFAMILY SSF56219 93 303 1.57E-29 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily Astex_2222 69e5f1cb7f6d3b043ec3728bf1e06543 303 Gene3D G3DSA:3.60.10.10 92 303 1.5E-27 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily Astex_0060 d2d57218daeacc757557a976876006fa 153 TIGRFAM TIGR00576 dut: dUTP diphosphatase 13 152 5.3E-53 T 13-10-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 Astex_0060 d2d57218daeacc757557a976876006fa 153 Gene3D G3DSA:2.70.40.10 4 151 7.5E-53 T 13-10-2018 IPR036157 dUTPase-like superfamily Astex_0060 d2d57218daeacc757557a976876006fa 153 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 5 152 33.413 T 13-10-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 Astex_0060 d2d57218daeacc757557a976876006fa 153 Pfam PF00692 dUTPase 20 151 2.0E-31 T 13-10-2018 IPR029054 dUTPase-like Astex_0060 d2d57218daeacc757557a976876006fa 153 SUPERFAMILY SSF51283 4 152 1.7E-49 T 13-10-2018 IPR036157 dUTPase-like superfamily Astex_2288 dd6b8c7b80f9a8d39a605b3cde1ff49a 304 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 31 259 1.5E-62 T 13-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 Astex_2288 dd6b8c7b80f9a8d39a605b3cde1ff49a 304 PIRSF PIRSF002936 2 304 5.0E-150 T 13-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 Astex_2288 dd6b8c7b80f9a8d39a605b3cde1ff49a 304 Gene3D G3DSA:3.40.50.620 9 214 6.7E-62 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Astex_2288 dd6b8c7b80f9a8d39a605b3cde1ff49a 304 Hamap MF_00064 Sulfate adenylyltransferase subunit 2 [cysD]. 6 304 56.682 T 13-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 Astex_2288 dd6b8c7b80f9a8d39a605b3cde1ff49a 304 SUPERFAMILY SSF52402 8 212 4.71E-71 T 13-10-2018 Astex_2288 dd6b8c7b80f9a8d39a605b3cde1ff49a 304 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 11 304 9.4E-155 T 13-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 Astex_1715 68cf845cfb5373efb8a3bbc7a7aef3f9 188 Hamap MF_00141 Elongation factor P [efp]. 2 187 44.299 T 13-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 Astex_1715 68cf845cfb5373efb8a3bbc7a7aef3f9 188 SMART SM01185 68 123 2.7E-23 T 13-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 Astex_1715 68cf845cfb5373efb8a3bbc7a7aef3f9 188 SMART SM00841 131 186 4.3E-27 T 13-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 Astex_1715 68cf845cfb5373efb8a3bbc7a7aef3f9 188 SUPERFAMILY SSF50104 3 64 8.42E-20 T 13-10-2018 IPR008991 Translation protein SH3-like domain superfamily Astex_1715 68cf845cfb5373efb8a3bbc7a7aef3f9 188 Gene3D G3DSA:2.40.50.140 65 129 4.8E-21 T 13-10-2018 Astex_1715 68cf845cfb5373efb8a3bbc7a7aef3f9 188 TIGRFAM TIGR00038 efp: translation elongation factor P 3 187 3.3E-71 T 13-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 Astex_1715 68cf845cfb5373efb8a3bbc7a7aef3f9 188 Gene3D G3DSA:2.40.50.140 130 187 3.2E-21 T 13-10-2018 Astex_1715 68cf845cfb5373efb8a3bbc7a7aef3f9 188 Pfam PF09285 Elongation factor P, C-terminal 131 186 3.1E-22 T 13-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 Astex_1715 68cf845cfb5373efb8a3bbc7a7aef3f9 188 SUPERFAMILY SSF50249 130 187 1.63E-16 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Astex_1715 68cf845cfb5373efb8a3bbc7a7aef3f9 188 SUPERFAMILY SSF50249 66 128 2.06E-17 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Astex_1715 68cf845cfb5373efb8a3bbc7a7aef3f9 188 PIRSF PIRSF005901 1 188 1.8E-68 T 13-10-2018 IPR020599 Translation elongation factor P/YeiP Astex_1715 68cf845cfb5373efb8a3bbc7a7aef3f9 188 Gene3D G3DSA:2.30.30.30 1 64 7.5E-25 T 13-10-2018 IPR014722 Ribosomal protein L2, domain 2 Astex_1715 68cf845cfb5373efb8a3bbc7a7aef3f9 188 Pfam PF01132 Elongation factor P (EF-P) OB domain 69 123 1.7E-22 T 13-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 Astex_1715 68cf845cfb5373efb8a3bbc7a7aef3f9 188 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 5 61 4.0E-24 T 13-10-2018 IPR013185 Translation elongation factor, KOW-like Astex_1534 667cdb5f1923f02dfa3d48e9f4045c2c 360 Gene3D G3DSA:3.30.9.10 92 304 2.0E-32 T 13-10-2018 Astex_1534 667cdb5f1923f02dfa3d48e9f4045c2c 360 Pfam PF01266 FAD dependent oxidoreductase 7 341 4.7E-29 T 13-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 Astex_1534 667cdb5f1923f02dfa3d48e9f4045c2c 360 Gene3D G3DSA:3.50.50.60 8 343 2.0E-32 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_1534 667cdb5f1923f02dfa3d48e9f4045c2c 360 SUPERFAMILY SSF51905 6 360 2.2E-24 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_1567 67be23194bfd3baf5948f82d33a1097e 328 Gene3D G3DSA:3.40.50.11270 28 112 1.7E-107 T 13-10-2018 Astex_1567 67be23194bfd3baf5948f82d33a1097e 328 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 17 301 37.208 T 13-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 Astex_1567 67be23194bfd3baf5948f82d33a1097e 328 Pfam PF02401 LytB protein 20 297 1.6E-89 T 13-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 Astex_1567 67be23194bfd3baf5948f82d33a1097e 328 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 20 298 3.3E-98 T 13-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 Astex_1567 67be23194bfd3baf5948f82d33a1097e 328 Gene3D G3DSA:3.40.1010.20 113 210 1.7E-107 T 13-10-2018 Astex_1567 67be23194bfd3baf5948f82d33a1097e 328 Gene3D G3DSA:3.40.1010.20 23 296 1.7E-107 T 13-10-2018 Astex_1366 668c98f3a537429876d01f9a0310ee96 338 Pfam PF00356 Bacterial regulatory proteins, lacI family 10 55 1.2E-11 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Astex_1366 668c98f3a537429876d01f9a0310ee96 338 Gene3D G3DSA:3.40.50.2300 172 300 2.3E-62 T 13-10-2018 Astex_1366 668c98f3a537429876d01f9a0310ee96 338 SUPERFAMILY SSF47413 8 66 3.38E-14 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Astex_1366 668c98f3a537429876d01f9a0310ee96 338 ProSitePatterns PS00356 LacI-type HTH domain signature. 11 29 - T 13-10-2018 Astex_1366 668c98f3a537429876d01f9a0310ee96 338 SMART SM00354 8 78 1.7E-15 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Astex_1366 668c98f3a537429876d01f9a0310ee96 338 Gene3D G3DSA:1.10.260.40 4 61 9.4E-17 T 13-10-2018 Astex_1366 668c98f3a537429876d01f9a0310ee96 338 Pfam PF13377 Periplasmic binding protein-like domain 181 338 1.4E-31 T 13-10-2018 Astex_1366 668c98f3a537429876d01f9a0310ee96 338 Gene3D G3DSA:3.40.50.2300 62 317 2.3E-62 T 13-10-2018 Astex_1366 668c98f3a537429876d01f9a0310ee96 338 SUPERFAMILY SSF53822 68 338 3.34E-53 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Astex_3675 fc26fe3d5388d73a15e88533932f4805 928 Gene3D G3DSA:2.170.130.10 35 180 1.5E-16 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_3675 fc26fe3d5388d73a15e88533932f4805 928 SUPERFAMILY SSF56935 45 928 2.52E-91 T 13-10-2018 Astex_3675 fc26fe3d5388d73a15e88533932f4805 928 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 44 928 3.9E-200 T 13-10-2018 IPR010104 Bacterial TonB-dependent receptor Astex_3675 fc26fe3d5388d73a15e88533932f4805 928 Pfam PF07715 TonB-dependent Receptor Plug Domain 61 174 7.4E-15 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_3675 fc26fe3d5388d73a15e88533932f4805 928 Pfam PF00593 TonB dependent receptor 423 927 3.2E-38 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_1022 a975c112c96a1172fd9a55beb2d96377 391 Pfam PF00285 Citrate synthase, C-terminal domain 24 372 1.8E-111 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 Astex_1022 a975c112c96a1172fd9a55beb2d96377 391 Gene3D G3DSA:1.10.230.10 239 337 2.1E-125 T 13-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain Astex_1022 a975c112c96a1172fd9a55beb2d96377 391 PIRSF PIRSF001369 16 391 2.1E-107 T 13-10-2018 IPR024176 Citrate synthase, bacterial-type Astex_1022 a975c112c96a1172fd9a55beb2d96377 391 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 23 390 6.8E-152 T 13-10-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 Astex_1022 a975c112c96a1172fd9a55beb2d96377 391 ProSitePatterns PS00480 Citrate synthase signature. 273 285 - T 13-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 Astex_1022 a975c112c96a1172fd9a55beb2d96377 391 PRINTS PR00143 Citrate synthase signature 343 357 3.0E-37 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 Astex_1022 a975c112c96a1172fd9a55beb2d96377 391 PRINTS PR00143 Citrate synthase signature 191 206 3.0E-37 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 Astex_1022 a975c112c96a1172fd9a55beb2d96377 391 PRINTS PR00143 Citrate synthase signature 266 286 3.0E-37 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 Astex_1022 a975c112c96a1172fd9a55beb2d96377 391 PRINTS PR00143 Citrate synthase signature 213 241 3.0E-37 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 Astex_1022 a975c112c96a1172fd9a55beb2d96377 391 PRINTS PR00143 Citrate synthase signature 141 154 3.0E-37 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 Astex_1022 a975c112c96a1172fd9a55beb2d96377 391 PRINTS PR00143 Citrate synthase signature 323 339 3.0E-37 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 Astex_1022 a975c112c96a1172fd9a55beb2d96377 391 Gene3D G3DSA:1.10.580.10 44 370 2.1E-125 T 13-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 Astex_1022 a975c112c96a1172fd9a55beb2d96377 391 SUPERFAMILY SSF48256 24 384 8.24E-123 T 13-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 Astex_3062 04c93c8f551ab2550731d9cccd49743e 621 Pfam PF02927 Cellulase N-terminal ig-like domain 38 121 3.0E-15 T 13-10-2018 IPR004197 Cellulase, Ig-like domain GO:0005975|GO:0008810 Astex_3062 04c93c8f551ab2550731d9cccd49743e 621 SUPERFAMILY SSF48208 136 617 3.48E-115 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 Astex_3062 04c93c8f551ab2550731d9cccd49743e 621 Gene3D G3DSA:1.50.10.10 136 620 2.5E-173 T 13-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 Astex_3062 04c93c8f551ab2550731d9cccd49743e 621 ProSitePatterns PS00592 Glycosyl hydrolases family 9 active sites signature 1. 531 547 - T 13-10-2018 IPR018221 Glycoside hydrolase family 9, His active site KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 Astex_3062 04c93c8f551ab2550731d9cccd49743e 621 SUPERFAMILY SSF81296 37 134 1.12E-15 T 13-10-2018 IPR014756 Immunoglobulin E-set Astex_3062 04c93c8f551ab2550731d9cccd49743e 621 Pfam PF00759 Glycosyl hydrolase family 9 138 612 1.2E-102 T 13-10-2018 IPR001701 Glycoside hydrolase family 9 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 Astex_3062 04c93c8f551ab2550731d9cccd49743e 621 ProSitePatterns PS00698 Glycosyl hydrolases family 9 active sites signature 2. 589 607 - T 13-10-2018 IPR033126 Glycosyl hydrolases family 9, Asp/Glu active sites KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 Astex_3062 04c93c8f551ab2550731d9cccd49743e 621 Gene3D G3DSA:2.60.40.10 36 135 9.3E-20 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_1261 f359a0af22c4cb2984799b2ee1460a8c 290 Pfam PF00581 Rhodanese-like domain 115 208 6.3E-7 T 13-10-2018 IPR001763 Rhodanese-like domain Astex_1261 f359a0af22c4cb2984799b2ee1460a8c 290 Gene3D G3DSA:3.40.250.10 103 251 1.4E-44 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily Astex_1261 f359a0af22c4cb2984799b2ee1460a8c 290 SMART SM00450 113 214 9.8E-17 T 13-10-2018 IPR001763 Rhodanese-like domain Astex_1261 f359a0af22c4cb2984799b2ee1460a8c 290 Gene3D G3DSA:3.30.70.100 2 98 5.6E-27 T 13-10-2018 Astex_1261 f359a0af22c4cb2984799b2ee1460a8c 290 SUPERFAMILY SSF52821 106 238 1.78E-28 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily Astex_1261 f359a0af22c4cb2984799b2ee1460a8c 290 Hamap MF_00469 UPF0176 protein YceA [yceA]. 4 255 39.966 T 13-10-2018 IPR020936 Uncharacterised protein family UPF0176 Astex_3562 7c770ad853caf6e656caf850f8e352fe 280 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 73 277 6.1E-69 T 13-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 Astex_3562 7c770ad853caf6e656caf850f8e352fe 280 Gene3D G3DSA:3.90.850.10 67 280 2.2E-83 T 13-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 Astex_3562 7c770ad853caf6e656caf850f8e352fe 280 SUPERFAMILY SSF56529 59 279 7.46E-80 T 13-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 Astex_0779 939221660a52aa81ed820b9bdd2f368c 327 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 18 322 2.4E-31 T 13-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 Astex_0779 939221660a52aa81ed820b9bdd2f368c 327 Gene3D G3DSA:3.40.50.720 6 317 9.8E-106 T 13-10-2018 Astex_0779 939221660a52aa81ed820b9bdd2f368c 327 SUPERFAMILY SSF51735 104 292 8.14E-57 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_0779 939221660a52aa81ed820b9bdd2f368c 327 SUPERFAMILY SSF52283 4 138 2.84E-35 T 13-10-2018 Astex_0779 939221660a52aa81ed820b9bdd2f368c 327 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 112 291 1.1E-54 T 13-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 Astex_0779 939221660a52aa81ed820b9bdd2f368c 327 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 152 179 - T 13-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 Astex_0779 939221660a52aa81ed820b9bdd2f368c 327 Gene3D G3DSA:3.40.50.720 101 291 9.8E-106 T 13-10-2018 Astex_2470 678accd5919fab458ae71d635da0f7f6 363 Gene3D G3DSA:3.10.28.20 275 355 2.4E-25 T 13-10-2018 Astex_2470 678accd5919fab458ae71d635da0f7f6 363 SUPERFAMILY SSF141130 23 353 5.23E-89 T 13-10-2018 Astex_2470 678accd5919fab458ae71d635da0f7f6 363 Gene3D G3DSA:2.60.120.580 178 273 2.3E-27 T 13-10-2018 Astex_2470 678accd5919fab458ae71d635da0f7f6 363 Gene3D G3DSA:2.60.120.580 12 137 6.6E-12 T 13-10-2018 Astex_2470 678accd5919fab458ae71d635da0f7f6 363 Pfam PF03069 Acetamidase/Formamidase family 205 339 4.8E-23 T 13-10-2018 IPR004304 Acetamidase/Formamidase GO:0016811 Astex_2470 678accd5919fab458ae71d635da0f7f6 363 Pfam PF03069 Acetamidase/Formamidase family 33 202 3.8E-11 T 13-10-2018 IPR004304 Acetamidase/Formamidase GO:0016811 Astex_1521 556aa0ce8ff90b0df4b450ad7a7c10bc 409 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 230 246 3.2E-26 T 13-10-2018 Astex_1521 556aa0ce8ff90b0df4b450ad7a7c10bc 409 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 255 277 3.2E-26 T 13-10-2018 Astex_1521 556aa0ce8ff90b0df4b450ad7a7c10bc 409 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 145 163 3.2E-26 T 13-10-2018 Astex_1521 556aa0ce8ff90b0df4b450ad7a7c10bc 409 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 3.2E-26 T 13-10-2018 Astex_1521 556aa0ce8ff90b0df4b450ad7a7c10bc 409 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 3.2E-26 T 13-10-2018 Astex_1521 556aa0ce8ff90b0df4b450ad7a7c10bc 409 Gene3D G3DSA:3.30.390.30 320 409 2.9E-29 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 Astex_1521 556aa0ce8ff90b0df4b450ad7a7c10bc 409 Pfam PF14759 Reductase C-terminal 320 404 3.2E-27 T 13-10-2018 IPR028202 Reductase, C-terminal Astex_1521 556aa0ce8ff90b0df4b450ad7a7c10bc 409 SUPERFAMILY SSF51905 3 184 5.06E-46 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_1521 556aa0ce8ff90b0df4b450ad7a7c10bc 409 SUPERFAMILY SSF51905 146 310 1.43E-26 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_1521 556aa0ce8ff90b0df4b450ad7a7c10bc 409 Gene3D G3DSA:3.50.50.60 113 237 1.0E-95 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_1521 556aa0ce8ff90b0df4b450ad7a7c10bc 409 SUPERFAMILY SSF55424 314 407 4.67E-23 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 Astex_1521 556aa0ce8ff90b0df4b450ad7a7c10bc 409 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.0E-18 T 13-10-2018 Astex_1521 556aa0ce8ff90b0df4b450ad7a7c10bc 409 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 145 170 1.0E-18 T 13-10-2018 Astex_1521 556aa0ce8ff90b0df4b450ad7a7c10bc 409 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 270 277 1.0E-18 T 13-10-2018 Astex_1521 556aa0ce8ff90b0df4b450ad7a7c10bc 409 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 231 245 1.0E-18 T 13-10-2018 Astex_1521 556aa0ce8ff90b0df4b450ad7a7c10bc 409 Gene3D G3DSA:3.50.50.60 5 308 1.0E-95 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_1521 556aa0ce8ff90b0df4b450ad7a7c10bc 409 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 301 4.5E-65 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Astex_2885 6e4148f9b3d8655bc2e5a95545f9b332 105 Gene3D G3DSA:1.10.150.250 17 102 1.0E-23 T 13-10-2018 IPR036714 Flavinator of succinate dehydrogenase superfamily Astex_2885 6e4148f9b3d8655bc2e5a95545f9b332 105 Pfam PF03937 Flavinator of succinate dehydrogenase 22 92 4.1E-24 T 13-10-2018 IPR005631 Flavinator of succinate dehydrogenase Astex_2885 6e4148f9b3d8655bc2e5a95545f9b332 105 SUPERFAMILY SSF109910 18 93 2.88E-22 T 13-10-2018 IPR036714 Flavinator of succinate dehydrogenase superfamily Astex_3383 0bf10ccf1c6a00f4df62fa15067fcec7 497 Gene3D G3DSA:3.50.50.60 6 495 2.5E-100 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_3383 0bf10ccf1c6a00f4df62fa15067fcec7 497 Pfam PF04820 Tryptophan halogenase 11 463 3.7E-82 T 13-10-2018 IPR006905 Flavin-dependent halogenase Astex_3383 0bf10ccf1c6a00f4df62fa15067fcec7 497 SUPERFAMILY SSF51905 143 407 6.49E-12 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_3830 704644e4e6eeb68497c1293507a70cad 620 SUPERFAMILY SSF49503 167 377 3.21E-53 T 13-10-2018 IPR008972 Cupredoxin Astex_3830 704644e4e6eeb68497c1293507a70cad 620 Pfam PF07732 Multicopper oxidase 52 163 8.4E-39 T 13-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 Astex_3830 704644e4e6eeb68497c1293507a70cad 620 Pfam PF00394 Multicopper oxidase 173 342 6.8E-27 T 13-10-2018 IPR001117 Multicopper oxidase, type 1 GO:0055114 Astex_3830 704644e4e6eeb68497c1293507a70cad 620 Gene3D G3DSA:2.60.40.420 39 162 1.8E-39 T 13-10-2018 IPR008972 Cupredoxin Astex_3830 704644e4e6eeb68497c1293507a70cad 620 ProSitePatterns PS00080 Multicopper oxidases signature 2. 595 606 - T 13-10-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 Astex_3830 704644e4e6eeb68497c1293507a70cad 620 TIGRFAM TIGR01480 copper_res_A: copper-resistance protein, CopA family 2 613 1.4E-238 T 13-10-2018 IPR006376 Copper-resistance protein CopA GO:0005507|GO:0042597 Astex_3830 704644e4e6eeb68497c1293507a70cad 620 ProSitePatterns PS00079 Multicopper oxidases signature 1. 590 610 - T 13-10-2018 IPR033138 Multicopper oxidases, conserved site Astex_3830 704644e4e6eeb68497c1293507a70cad 620 Pfam PF07731 Multicopper oxidase 496 614 9.3E-28 T 13-10-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 Astex_3830 704644e4e6eeb68497c1293507a70cad 620 SUPERFAMILY SSF49503 466 612 1.05E-36 T 13-10-2018 IPR008972 Cupredoxin Astex_3830 704644e4e6eeb68497c1293507a70cad 620 Gene3D G3DSA:2.60.40.420 169 369 2.4E-36 T 13-10-2018 IPR008972 Cupredoxin Astex_3830 704644e4e6eeb68497c1293507a70cad 620 SUPERFAMILY SSF49503 48 192 1.25E-36 T 13-10-2018 IPR008972 Cupredoxin Astex_3830 704644e4e6eeb68497c1293507a70cad 620 Gene3D G3DSA:2.60.40.420 489 614 9.6E-32 T 13-10-2018 IPR008972 Cupredoxin Astex_1557 ec075af1d061f1189e7a472d7af0bcdc 472 PIRSF PIRSF000204 2 472 1.4E-214 T 13-10-2018 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2 Astex_1557 ec075af1d061f1189e7a472d7af0bcdc 472 Gene3D G3DSA:3.40.50.1220 295 472 6.3E-82 T 13-10-2018 Astex_1557 ec075af1d061f1189e7a472d7af0bcdc 472 Pfam PF02233 NAD(P) transhydrogenase beta subunit 9 470 2.3E-194 T 13-10-2018 IPR034300 NADP transhydrogenase beta-like domain KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 Astex_1557 ec075af1d061f1189e7a472d7af0bcdc 472 SUPERFAMILY SSF52467 301 472 5.06E-75 T 13-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily Astex_0256 c3084b57cca211408d88a04e1511226e 252 Pfam PF04340 Protein of unknown function, DUF484 54 250 3.0E-30 T 13-10-2018 IPR007435 Protein of unknown function DUF484 Astex_0256 c3084b57cca211408d88a04e1511226e 252 Gene3D G3DSA:3.30.450.40 79 250 7.5E-17 T 13-10-2018 IPR029016 GAF-like domain superfamily Astex_3340 62349af4d3eb9b51ed1f129423bf0716 480 Gene3D G3DSA:3.30.450.20 13 132 2.3E-20 T 13-10-2018 Astex_3340 62349af4d3eb9b51ed1f129423bf0716 480 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 19 129 3.6E-13 T 13-10-2018 IPR000014 PAS domain Astex_3340 62349af4d3eb9b51ed1f129423bf0716 480 SUPERFAMILY SSF55785 20 117 9.42E-21 T 13-10-2018 IPR035965 PAS domain superfamily Astex_3340 62349af4d3eb9b51ed1f129423bf0716 480 Gene3D G3DSA:1.10.287.950 235 478 4.0E-44 T 13-10-2018 Astex_3340 62349af4d3eb9b51ed1f129423bf0716 480 Gene3D G3DSA:3.30.450.20 133 234 1.2E-20 T 13-10-2018 Astex_3340 62349af4d3eb9b51ed1f129423bf0716 480 Pfam PF13426 PAS domain 141 228 6.9E-4 T 13-10-2018 IPR000014 PAS domain Astex_3340 62349af4d3eb9b51ed1f129423bf0716 480 Pfam PF13426 PAS domain 22 116 3.4E-11 T 13-10-2018 IPR000014 PAS domain Astex_3340 62349af4d3eb9b51ed1f129423bf0716 480 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 313 460 4.3E-27 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_3340 62349af4d3eb9b51ed1f129423bf0716 480 SUPERFAMILY SSF58104 172 476 2.35E-50 T 13-10-2018 Astex_3340 62349af4d3eb9b51ed1f129423bf0716 480 SMART SM00091 10 77 0.17 T 13-10-2018 IPR000014 PAS domain Astex_3340 62349af4d3eb9b51ed1f129423bf0716 480 SMART SM00091 131 199 5.5 T 13-10-2018 IPR000014 PAS domain Astex_3340 62349af4d3eb9b51ed1f129423bf0716 480 SMART SM00283 237 477 1.1E-34 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_2808 62f83c939dd7e02cc372623884c0074c 437 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 11 419 1.2E-194 T 13-10-2018 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2808 62f83c939dd7e02cc372623884c0074c 437 Gene3D G3DSA:3.10.20.600 234 330 3.2E-41 T 13-10-2018 Astex_2808 62f83c939dd7e02cc372623884c0074c 437 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 335 417 3.2E-30 T 13-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2808 62f83c939dd7e02cc372623884c0074c 437 SUPERFAMILY SSF142984 243 328 1.23E-24 T 13-10-2018 Astex_2808 62f83c939dd7e02cc372623884c0074c 437 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 50 220 1.1E-49 T 13-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2808 62f83c939dd7e02cc372623884c0074c 437 SMART SM00928 333 378 1.5E-25 T 13-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2808 62f83c939dd7e02cc372623884c0074c 437 Pfam PF10531 SLBB domain 245 294 8.6E-9 T 13-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2808 62f83c939dd7e02cc372623884c0074c 437 SUPERFAMILY SSF140490 329 420 9.15E-36 T 13-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2808 62f83c939dd7e02cc372623884c0074c 437 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 346 357 - T 13-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2808 62f83c939dd7e02cc372623884c0074c 437 Gene3D G3DSA:3.40.50.11540 55 233 9.5E-79 T 13-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2808 62f83c939dd7e02cc372623884c0074c 437 Gene3D G3DSA:1.20.1440.230 331 430 1.0E-37 T 13-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2808 62f83c939dd7e02cc372623884c0074c 437 SUPERFAMILY SSF142019 7 242 5.1E-82 T 13-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2997 eb11bf0e5d62c42907eed1450416961e 467 Gene3D G3DSA:3.30.2010.10 37 123 2.0E-6 T 13-10-2018 Astex_2997 eb11bf0e5d62c42907eed1450416961e 467 Pfam PF01435 Peptidase family M48 49 234 6.4E-29 T 13-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 Astex_2997 eb11bf0e5d62c42907eed1450416961e 467 Gene3D G3DSA:1.25.40.10 231 444 2.5E-17 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_2997 eb11bf0e5d62c42907eed1450416961e 467 SUPERFAMILY SSF48452 285 418 4.67E-16 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_0545 05469e7d0e88886f2e98e76f95098c54 655 Gene3D G3DSA:3.40.50.300 205 372 1.1E-19 T 13-10-2018 Astex_0545 05469e7d0e88886f2e98e76f95098c54 655 Gene3D G3DSA:3.40.50.300 436 596 5.3E-37 T 13-10-2018 Astex_0545 05469e7d0e88886f2e98e76f95098c54 655 SMART SM00382 221 356 3.3E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_0545 05469e7d0e88886f2e98e76f95098c54 655 SMART SM00382 457 586 1.0E-15 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_0545 05469e7d0e88886f2e98e76f95098c54 655 SUPERFAMILY SSF52540 219 399 1.08E-22 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0545 05469e7d0e88886f2e98e76f95098c54 655 SUPERFAMILY SSF52540 447 626 3.58E-35 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0545 05469e7d0e88886f2e98e76f95098c54 655 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 225 352 6.9E-11 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Astex_0545 05469e7d0e88886f2e98e76f95098c54 655 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 461 581 4.9E-27 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Astex_3033 d0c8d998ccd883653b80fc6672f4aab9 277 SUPERFAMILY SSF53335 13 277 2.05E-66 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Astex_3033 d0c8d998ccd883653b80fc6672f4aab9 277 Gene3D G3DSA:3.40.50.150 1 215 9.5E-64 T 13-10-2018 Astex_3033 d0c8d998ccd883653b80fc6672f4aab9 277 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 17 276 1.2E-68 T 13-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 Astex_3033 d0c8d998ccd883653b80fc6672f4aab9 277 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 15 277 47.419 T 13-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 Astex_3033 d0c8d998ccd883653b80fc6672f4aab9 277 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 51 79 - T 13-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 Astex_3033 d0c8d998ccd883653b80fc6672f4aab9 277 Pfam PF00398 Ribosomal RNA adenine dimethylase 17 276 3.5E-46 T 13-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm Astex_3033 d0c8d998ccd883653b80fc6672f4aab9 277 SMART SM00650 31 212 1.3E-58 T 13-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 Astex_3033 d0c8d998ccd883653b80fc6672f4aab9 277 Gene3D G3DSA:1.10.8.100 216 277 1.2E-19 T 13-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 Astex_2236 caab90a4d9a5fcbb80a0bd6bf7096d7c 328 Gene3D G3DSA:3.40.50.300 110 325 1.0E-59 T 13-10-2018 Astex_2236 caab90a4d9a5fcbb80a0bd6bf7096d7c 328 Gene3D G3DSA:3.30.450.90 1 108 1.1E-30 T 13-10-2018 Astex_2236 caab90a4d9a5fcbb80a0bd6bf7096d7c 328 SUPERFAMILY SSF52540 6 312 6.68E-46 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2236 caab90a4d9a5fcbb80a0bd6bf7096d7c 328 SMART SM00382 149 324 0.0017 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_2236 caab90a4d9a5fcbb80a0bd6bf7096d7c 328 Pfam PF00437 Type II/IV secretion system protein 8 301 6.3E-51 T 13-10-2018 IPR001482 Type II/IV secretion system protein Astex_2236 caab90a4d9a5fcbb80a0bd6bf7096d7c 328 TIGRFAM TIGR02788 VirB11: P-type DNA transfer ATPase VirB11 12 307 1.1E-96 T 13-10-2018 IPR014155 Type IV secretion system protein VirB11 GO:0043684|GO:0044097 Astex_1422 177c314c52dd82c7726aa1aeafa41a23 106 Pfam PF04347 Flagellar biosynthesis protein, FliO 26 84 3.6E-10 T 13-10-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 Astex_2239 0abb75c56ad0fc7d7fdee55380bffbb5 246 Gene3D G3DSA:3.10.450.230 91 234 3.4E-41 T 13-10-2018 Astex_2239 0abb75c56ad0fc7d7fdee55380bffbb5 246 SUPERFAMILY SSF54427 92 231 2.85E-36 T 13-10-2018 IPR032710 NTF2-like domain superfamily Astex_2239 0abb75c56ad0fc7d7fdee55380bffbb5 246 PIRSF PIRSF003299 7 234 3.2E-47 T 13-10-2018 IPR026264 Type IV secretion system protein VirB8/PtlE GO:0030255 Astex_2239 0abb75c56ad0fc7d7fdee55380bffbb5 246 Pfam PF04335 VirB8 protein 18 231 6.5E-44 T 13-10-2018 IPR007430 Bacterial virulence protein VirB8 GO:0016020 Astex_2716 eea7ed5f32821e655e1c69f2b884985c 200 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 7 187 6.8E-24 T 13-10-2018 Astex_2716 eea7ed5f32821e655e1c69f2b884985c 200 SUPERFAMILY SSF56784 5 188 1.81E-16 T 13-10-2018 IPR036412 HAD-like superfamily Astex_2716 eea7ed5f32821e655e1c69f2b884985c 200 Pfam PF12710 haloacid dehalogenase-like hydrolase 8 185 1.5E-25 T 13-10-2018 Astex_2716 eea7ed5f32821e655e1c69f2b884985c 200 Gene3D G3DSA:3.40.50.1000 8 188 5.9E-23 T 13-10-2018 IPR023214 HAD superfamily Astex_2716 eea7ed5f32821e655e1c69f2b884985c 200 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 7 192 1.8E-29 T 13-10-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like Astex_2716 eea7ed5f32821e655e1c69f2b884985c 200 Gene3D G3DSA:1.20.1440.100 17 88 5.9E-23 T 13-10-2018 Astex_2320 4cf2b4d6cc4be57f9840eb9fe3c1bfe0 228 Pfam PF01895 PhoU domain 22 107 1.5E-22 T 13-10-2018 IPR026022 PhoU domain Astex_2320 4cf2b4d6cc4be57f9840eb9fe3c1bfe0 228 Pfam PF01895 PhoU domain 124 208 5.4E-18 T 13-10-2018 IPR026022 PhoU domain Astex_2320 4cf2b4d6cc4be57f9840eb9fe3c1bfe0 228 Gene3D G3DSA:1.20.58.220 1 116 2.3E-39 T 13-10-2018 IPR038078 PhoU-like domain superfamily Astex_2320 4cf2b4d6cc4be57f9840eb9fe3c1bfe0 228 SUPERFAMILY SSF109755 7 220 1.78E-69 T 13-10-2018 Astex_2320 4cf2b4d6cc4be57f9840eb9fe3c1bfe0 228 Gene3D G3DSA:1.20.58.220 117 227 7.8E-35 T 13-10-2018 IPR038078 PhoU-like domain superfamily Astex_2320 4cf2b4d6cc4be57f9840eb9fe3c1bfe0 228 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 8 217 1.0E-71 T 13-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 Astex_2320 4cf2b4d6cc4be57f9840eb9fe3c1bfe0 228 PIRSF PIRSF003107 2 222 1.5E-66 T 13-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 Astex_3119 f7ce6178a744ce05864f33b78442794a 887 Gene3D G3DSA:3.30.1490.20 15 247 3.7E-105 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 Astex_3119 f7ce6178a744ce05864f33b78442794a 887 Gene3D G3DSA:1.10.189.10 361 543 7.4E-76 T 13-10-2018 Astex_3119 f7ce6178a744ce05864f33b78442794a 887 Gene3D G3DSA:3.20.20.60 546 886 1.1E-150 T 13-10-2018 Astex_3119 f7ce6178a744ce05864f33b78442794a 887 SUPERFAMILY SSF56059 3 394 1.65E-144 T 13-10-2018 Astex_3119 f7ce6178a744ce05864f33b78442794a 887 SUPERFAMILY SSF51621 525 884 1.54E-129 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 Astex_3119 f7ce6178a744ce05864f33b78442794a 887 TIGRFAM TIGR01828 pyru_phos_dikin: pyruvate, phosphate dikinase 4 884 0.0 T 13-10-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Astex_3119 f7ce6178a744ce05864f33b78442794a 887 SUPERFAMILY SSF52009 403 525 1.26E-37 T 13-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 Astex_3119 f7ce6178a744ce05864f33b78442794a 887 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 533 882 4.2E-91 T 13-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 Astex_3119 f7ce6178a744ce05864f33b78442794a 887 Gene3D G3DSA:3.30.470.20 248 357 3.8E-39 T 13-10-2018 Astex_3119 f7ce6178a744ce05864f33b78442794a 887 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 464 475 - T 13-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 Astex_3119 f7ce6178a744ce05864f33b78442794a 887 Gene3D G3DSA:3.50.30.10 399 523 7.4E-76 T 13-10-2018 Astex_3119 f7ce6178a744ce05864f33b78442794a 887 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 66 372 4.6E-52 T 13-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 Astex_3119 f7ce6178a744ce05864f33b78442794a 887 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 22 60 2.6E-10 T 13-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 Astex_3119 f7ce6178a744ce05864f33b78442794a 887 Pfam PF00391 PEP-utilising enzyme, mobile domain 436 517 1.3E-27 T 13-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 Astex_3119 f7ce6178a744ce05864f33b78442794a 887 PIRSF PIRSF000853 2 887 0.0 T 13-10-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Astex_3119 f7ce6178a744ce05864f33b78442794a 887 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 774 792 - T 13-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 Astex_3119 f7ce6178a744ce05864f33b78442794a 887 Gene3D G3DSA:1.20.80.30 115 202 3.7E-105 T 13-10-2018 Astex_0366 b53bbd04ac142a2e9f7368791ad4b8ad 225 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 115 224 1.6E-18 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_0366 b53bbd04ac142a2e9f7368791ad4b8ad 225 Gene3D G3DSA:3.30.565.10 77 225 4.6E-29 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_0366 b53bbd04ac142a2e9f7368791ad4b8ad 225 Gene3D G3DSA:1.10.287.130 4 72 5.0E-7 T 13-10-2018 Astex_0366 b53bbd04ac142a2e9f7368791ad4b8ad 225 SMART SM00388 6 74 0.0079 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_0366 b53bbd04ac142a2e9f7368791ad4b8ad 225 SUPERFAMILY SSF55874 65 224 6.68E-29 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_0366 b53bbd04ac142a2e9f7368791ad4b8ad 225 SUPERFAMILY SSF47384 5 72 1.06E-8 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Astex_0366 b53bbd04ac142a2e9f7368791ad4b8ad 225 SMART SM00387 115 225 1.8E-21 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_0366 b53bbd04ac142a2e9f7368791ad4b8ad 225 PRINTS PR00344 Bacterial sensor protein C-terminal signature 187 205 1.8E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_0366 b53bbd04ac142a2e9f7368791ad4b8ad 225 PRINTS PR00344 Bacterial sensor protein C-terminal signature 154 168 1.8E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_0366 b53bbd04ac142a2e9f7368791ad4b8ad 225 PRINTS PR00344 Bacterial sensor protein C-terminal signature 210 223 1.8E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_0364 da9655a3f9b44bc08840af252c886906 411 SUPERFAMILY SSF48264 15 410 1.83E-84 T 13-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 Astex_0364 da9655a3f9b44bc08840af252c886906 411 PRINTS PR00359 B-class P450 signature 362 373 5.3E-42 T 13-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Astex_0364 da9655a3f9b44bc08840af252c886906 411 PRINTS PR00359 B-class P450 signature 164 179 5.3E-42 T 13-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Astex_0364 da9655a3f9b44bc08840af252c886906 411 PRINTS PR00359 B-class P450 signature 207 229 5.3E-42 T 13-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Astex_0364 da9655a3f9b44bc08840af252c886906 411 PRINTS PR00359 B-class P450 signature 332 347 5.3E-42 T 13-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Astex_0364 da9655a3f9b44bc08840af252c886906 411 PRINTS PR00359 B-class P450 signature 147 163 5.3E-42 T 13-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Astex_0364 da9655a3f9b44bc08840af252c886906 411 PRINTS PR00359 B-class P450 signature 353 362 5.3E-42 T 13-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Astex_0364 da9655a3f9b44bc08840af252c886906 411 PRINTS PR00359 B-class P450 signature 287 298 5.3E-42 T 13-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Astex_0364 da9655a3f9b44bc08840af252c886906 411 PRINTS PR00359 B-class P450 signature 103 114 5.3E-42 T 13-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Astex_0364 da9655a3f9b44bc08840af252c886906 411 PRINTS PR00359 B-class P450 signature 304 331 5.3E-42 T 13-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 Astex_0364 da9655a3f9b44bc08840af252c886906 411 Gene3D G3DSA:1.10.630.10 6 411 1.4E-113 T 13-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 Astex_0364 da9655a3f9b44bc08840af252c886906 411 Pfam PF00067 Cytochrome P450 214 280 2.8E-5 T 13-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Astex_0364 da9655a3f9b44bc08840af252c886906 411 Pfam PF00067 Cytochrome P450 285 386 6.6E-21 T 13-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Astex_2477 aa419cce18da127ddb3ee146b53c2d33 323 Pfam PF00175 Oxidoreductase NAD-binding domain 117 208 2.8E-5 T 13-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 Astex_2477 aa419cce18da127ddb3ee146b53c2d33 323 Gene3D G3DSA:3.10.20.30 227 323 1.4E-26 T 13-10-2018 IPR012675 Beta-grasp domain superfamily Astex_2477 aa419cce18da127ddb3ee146b53c2d33 323 SUPERFAMILY SSF52343 105 224 1.31E-23 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain Astex_2477 aa419cce18da127ddb3ee146b53c2d33 323 SUPERFAMILY SSF63380 20 103 1.24E-20 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel Astex_2477 aa419cce18da127ddb3ee146b53c2d33 323 PRINTS PR00409 Phthalate dioxygenase reductase family signature 196 204 1.4E-40 T 13-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 Astex_2477 aa419cce18da127ddb3ee146b53c2d33 323 PRINTS PR00409 Phthalate dioxygenase reductase family signature 56 70 1.4E-40 T 13-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 Astex_2477 aa419cce18da127ddb3ee146b53c2d33 323 PRINTS PR00409 Phthalate dioxygenase reductase family signature 94 108 1.4E-40 T 13-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 Astex_2477 aa419cce18da127ddb3ee146b53c2d33 323 PRINTS PR00409 Phthalate dioxygenase reductase family signature 141 150 1.4E-40 T 13-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 Astex_2477 aa419cce18da127ddb3ee146b53c2d33 323 PRINTS PR00409 Phthalate dioxygenase reductase family signature 34 44 1.4E-40 T 13-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 Astex_2477 aa419cce18da127ddb3ee146b53c2d33 323 PRINTS PR00409 Phthalate dioxygenase reductase family signature 116 135 1.4E-40 T 13-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 Astex_2477 aa419cce18da127ddb3ee146b53c2d33 323 PRINTS PR00409 Phthalate dioxygenase reductase family signature 80 94 1.4E-40 T 13-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 Astex_2477 aa419cce18da127ddb3ee146b53c2d33 323 PRINTS PR00409 Phthalate dioxygenase reductase family signature 44 56 1.4E-40 T 13-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 Astex_2477 aa419cce18da127ddb3ee146b53c2d33 323 SUPERFAMILY SSF54292 217 321 3.01E-28 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 Astex_2477 aa419cce18da127ddb3ee146b53c2d33 323 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 247 312 5.0E-12 T 13-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 Astex_2477 aa419cce18da127ddb3ee146b53c2d33 323 Gene3D G3DSA:3.40.50.80 106 226 2.7E-22 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain Astex_2477 aa419cce18da127ddb3ee146b53c2d33 323 Gene3D G3DSA:2.40.30.10 5 104 2.6E-22 T 13-10-2018 Astex_2477 aa419cce18da127ddb3ee146b53c2d33 323 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 272 280 - T 13-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 Astex_1991 fe27a3bf8c1a23fcd78dc2f2b92438d2 279 Pfam PF12146 Serine aminopeptidase, S33 69 173 3.3E-11 T 13-10-2018 IPR022742 Serine aminopeptidase, S33 Astex_1991 fe27a3bf8c1a23fcd78dc2f2b92438d2 279 SUPERFAMILY SSF53474 43 278 6.97E-32 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1991 fe27a3bf8c1a23fcd78dc2f2b92438d2 279 Gene3D G3DSA:3.40.50.1820 51 279 1.4E-27 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1991 fe27a3bf8c1a23fcd78dc2f2b92438d2 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 96 111 7.8E-5 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Astex_1991 fe27a3bf8c1a23fcd78dc2f2b92438d2 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 137 150 7.8E-5 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Astex_0824 0f22cda9cf9b762ed74296790e5d99c0 303 Gene3D G3DSA:1.10.3720.10 9 299 1.9E-44 T 13-10-2018 IPR035906 MetI-like superfamily Astex_0824 0f22cda9cf9b762ed74296790e5d99c0 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 64 296 7.1E-9 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Astex_0824 0f22cda9cf9b762ed74296790e5d99c0 303 SUPERFAMILY SSF161098 13 290 3.27E-46 T 13-10-2018 IPR035906 MetI-like superfamily Astex_3077 2415cb7554be5808417c9959da0ff361 205 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 205 31.683 T 13-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 Astex_3077 2415cb7554be5808417c9959da0ff361 205 Gene3D G3DSA:1.10.1050.10 7 204 2.0E-70 T 13-10-2018 Astex_3077 2415cb7554be5808417c9959da0ff361 205 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 5 93 1.5E-23 T 13-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 Astex_3077 2415cb7554be5808417c9959da0ff361 205 ProSitePatterns PS00632 Ribosomal protein S4 signature. 92 116 - T 13-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_3077 2415cb7554be5808417c9959da0ff361 205 SMART SM01390 3 93 4.4E-40 T 13-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 Astex_3077 2415cb7554be5808417c9959da0ff361 205 SMART SM00363 94 158 2.1E-16 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_3077 2415cb7554be5808417c9959da0ff361 205 Pfam PF01479 S4 domain 95 141 4.0E-17 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_3077 2415cb7554be5808417c9959da0ff361 205 SUPERFAMILY SSF55174 5 204 1.31E-61 T 13-10-2018 Astex_3077 2415cb7554be5808417c9959da0ff361 205 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 6 204 9.2E-73 T 13-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 Astex_3077 2415cb7554be5808417c9959da0ff361 205 Gene3D G3DSA:3.10.290.10 93 188 2.0E-70 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 Astex_3169 edd6e42b60751a8b5fef361b9f4b16d7 489 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 16 487 1.9E-158 T 13-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 Astex_3169 edd6e42b60751a8b5fef361b9f4b16d7 489 Pfam PF02934 GatB/GatE catalytic domain 18 301 3.3E-109 T 13-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 Astex_3169 edd6e42b60751a8b5fef361b9f4b16d7 489 Gene3D G3DSA:1.10.10.410 428 488 2.3E-19 T 13-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal Astex_3169 edd6e42b60751a8b5fef361b9f4b16d7 489 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 15 488 36.63 T 13-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 Astex_3169 edd6e42b60751a8b5fef361b9f4b16d7 489 SUPERFAMILY SSF55931 17 308 8.5E-113 T 13-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Astex_3169 edd6e42b60751a8b5fef361b9f4b16d7 489 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 157 171 - T 13-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 Astex_3169 edd6e42b60751a8b5fef361b9f4b16d7 489 SMART SM00845 340 487 1.0E-75 T 13-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 Astex_3169 edd6e42b60751a8b5fef361b9f4b16d7 489 SUPERFAMILY SSF89095 309 412 1.31E-33 T 13-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 Astex_3169 edd6e42b60751a8b5fef361b9f4b16d7 489 Gene3D G3DSA:1.10.150.380 309 427 8.0E-39 T 13-10-2018 Astex_3169 edd6e42b60751a8b5fef361b9f4b16d7 489 Pfam PF02637 GatB domain 340 487 5.4E-49 T 13-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 Astex_2957 64a44a355c37dd01489b87e84cddaa35 132 Gene3D G3DSA:2.170.150.70 3 132 1.0E-15 T 13-10-2018 Astex_2957 64a44a355c37dd01489b87e84cddaa35 132 SUPERFAMILY SSF51316 1 83 3.35E-17 T 13-10-2018 IPR011057 Mss4-like superfamily Astex_0191 0778d33c3880df8f95b904ca08c76ee6 142 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 1 117 3.2E-48 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0191 0778d33c3880df8f95b904ca08c76ee6 142 Gene3D G3DSA:2.30.30.790 2 132 2.2E-14 T 13-10-2018 IPR038657 Ribosomal protein L19 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0191 0778d33c3880df8f95b904ca08c76ee6 142 PIRSF PIRSF002191 1 138 1.5E-52 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0191 0778d33c3880df8f95b904ca08c76ee6 142 Pfam PF01245 Ribosomal protein L19 3 116 4.9E-48 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0191 0778d33c3880df8f95b904ca08c76ee6 142 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 2 118 30.534 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0191 0778d33c3880df8f95b904ca08c76ee6 142 SUPERFAMILY SSF50104 2 120 4.41E-44 T 13-10-2018 IPR008991 Translation protein SH3-like domain superfamily Astex_0191 0778d33c3880df8f95b904ca08c76ee6 142 ProSitePatterns PS01015 Ribosomal protein L19 signature. 90 105 - T 13-10-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_0191 0778d33c3880df8f95b904ca08c76ee6 142 PRINTS PR00061 Ribosomal protein L19 signature 92 117 1.6E-36 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0191 0778d33c3880df8f95b904ca08c76ee6 142 PRINTS PR00061 Ribosomal protein L19 signature 38 67 1.6E-36 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0191 0778d33c3880df8f95b904ca08c76ee6 142 PRINTS PR00061 Ribosomal protein L19 signature 8 37 1.6E-36 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_3435 4ea368ef25fcb468378250faaf796a8c 724 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 157 720 1.7E-144 T 13-10-2018 Astex_3435 4ea368ef25fcb468378250faaf796a8c 724 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 176 719 2.9E-147 T 13-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 Astex_3435 4ea368ef25fcb468378250faaf796a8c 724 SUPERFAMILY SSF81665 205 685 2.48E-12 T 13-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 Astex_3435 4ea368ef25fcb468378250faaf796a8c 724 SUPERFAMILY SSF56784 436 716 1.76E-42 T 13-10-2018 IPR036412 HAD-like superfamily Astex_3435 4ea368ef25fcb468378250faaf796a8c 724 Pfam PF00122 E1-E2 ATPase 239 417 6.2E-45 T 13-10-2018 Astex_3435 4ea368ef25fcb468378250faaf796a8c 724 Gene3D G3DSA:2.70.150.20 238 342 1.6E-22 T 13-10-2018 Astex_3435 4ea368ef25fcb468378250faaf796a8c 724 SUPERFAMILY SSF55008 17 91 6.02E-13 T 13-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 Astex_3435 4ea368ef25fcb468378250faaf796a8c 724 SUPERFAMILY SSF81653 241 336 9.81E-19 T 13-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 Astex_3435 4ea368ef25fcb468378250faaf796a8c 724 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 564 574 3.5E-14 T 13-10-2018 Astex_3435 4ea368ef25fcb468378250faaf796a8c 724 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 640 652 3.5E-14 T 13-10-2018 Astex_3435 4ea368ef25fcb468378250faaf796a8c 724 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 287 301 3.5E-14 T 13-10-2018 Astex_3435 4ea368ef25fcb468378250faaf796a8c 724 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 617 636 3.5E-14 T 13-10-2018 Astex_3435 4ea368ef25fcb468378250faaf796a8c 724 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 438 452 3.5E-14 T 13-10-2018 Astex_3435 4ea368ef25fcb468378250faaf796a8c 724 PRINTS PR00943 Copper-transporting ATPase signature 360 374 3.9E-6 T 13-10-2018 Astex_3435 4ea368ef25fcb468378250faaf796a8c 724 PRINTS PR00943 Copper-transporting ATPase signature 594 611 3.9E-6 T 13-10-2018 Astex_3435 4ea368ef25fcb468378250faaf796a8c 724 PRINTS PR00943 Copper-transporting ATPase signature 421 436 3.9E-6 T 13-10-2018 Astex_3435 4ea368ef25fcb468378250faaf796a8c 724 PRINTS PR00943 Copper-transporting ATPase signature 66 86 3.9E-6 T 13-10-2018 Astex_3435 4ea368ef25fcb468378250faaf796a8c 724 PRINTS PR00943 Copper-transporting ATPase signature 207 226 3.9E-6 T 13-10-2018 Astex_3435 4ea368ef25fcb468378250faaf796a8c 724 PRINTS PR00943 Copper-transporting ATPase signature 227 245 3.9E-6 T 13-10-2018 Astex_3435 4ea368ef25fcb468378250faaf796a8c 724 Pfam PF00403 Heavy-metal-associated domain 24 84 1.5E-7 T 13-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 Astex_3435 4ea368ef25fcb468378250faaf796a8c 724 Gene3D G3DSA:3.40.1110.10 448 549 1.7E-60 T 13-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 Astex_3435 4ea368ef25fcb468378250faaf796a8c 724 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 206 719 1.1E-102 T 13-10-2018 Astex_3435 4ea368ef25fcb468378250faaf796a8c 724 Gene3D G3DSA:3.30.70.100 18 88 2.6E-12 T 13-10-2018 Astex_3435 4ea368ef25fcb468378250faaf796a8c 724 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 209 703 8.0E-64 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Astex_3435 4ea368ef25fcb468378250faaf796a8c 724 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 440 446 - T 13-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 Astex_3435 4ea368ef25fcb468378250faaf796a8c 724 Pfam PF00702 haloacid dehalogenase-like hydrolase 435 630 3.5E-35 T 13-10-2018 Astex_3435 4ea368ef25fcb468378250faaf796a8c 724 Gene3D G3DSA:3.40.50.1000 418 654 1.7E-60 T 13-10-2018 IPR023214 HAD superfamily Astex_0981 d10f237a12e22b0d2f70f834dba2dcf0 153 SMART SM00347 30 130 5.5E-15 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Astex_0981 d10f237a12e22b0d2f70f834dba2dcf0 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 54 70 3.9E-10 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Astex_0981 d10f237a12e22b0d2f70f834dba2dcf0 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 71 86 3.9E-10 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Astex_0981 d10f237a12e22b0d2f70f834dba2dcf0 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 90 106 3.9E-10 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Astex_0981 d10f237a12e22b0d2f70f834dba2dcf0 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 120 140 3.9E-10 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Astex_0981 d10f237a12e22b0d2f70f834dba2dcf0 153 Pfam PF12802 MarR family 35 94 3.1E-10 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Astex_0981 d10f237a12e22b0d2f70f834dba2dcf0 153 Gene3D G3DSA:1.10.10.10 2 148 5.0E-37 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_0981 d10f237a12e22b0d2f70f834dba2dcf0 153 SUPERFAMILY SSF46785 6 145 2.23E-31 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_1549 b21b81443c638e3a83b8bdfd2cd6a75b 487 Pfam PF02954 Bacterial regulatory protein, Fis family 437 475 2.5E-13 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Astex_1549 b21b81443c638e3a83b8bdfd2cd6a75b 487 SMART SM00382 164 311 8.6E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_1549 b21b81443c638e3a83b8bdfd2cd6a75b 487 Gene3D G3DSA:1.10.10.60 431 475 1.3E-12 T 13-10-2018 Astex_1549 b21b81443c638e3a83b8bdfd2cd6a75b 487 SUPERFAMILY SSF46689 422 480 1.38E-12 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Astex_1549 b21b81443c638e3a83b8bdfd2cd6a75b 487 Pfam PF00158 Sigma-54 interaction domain 144 311 8.0E-68 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 Astex_1549 b21b81443c638e3a83b8bdfd2cd6a75b 487 SUPERFAMILY SSF52540 143 386 3.45E-72 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1549 b21b81443c638e3a83b8bdfd2cd6a75b 487 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 357 366 - T 13-10-2018 IPR025944 Sigma-54 interaction domain, conserved site Astex_1549 b21b81443c638e3a83b8bdfd2cd6a75b 487 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 168 181 - T 13-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 Astex_1549 b21b81443c638e3a83b8bdfd2cd6a75b 487 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 460 480 1.5E-6 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Astex_1549 b21b81443c638e3a83b8bdfd2cd6a75b 487 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 443 460 1.5E-6 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Astex_1549 b21b81443c638e3a83b8bdfd2cd6a75b 487 SUPERFAMILY SSF52172 3 186 3.98E-42 T 13-10-2018 IPR011006 CheY-like superfamily Astex_1549 b21b81443c638e3a83b8bdfd2cd6a75b 487 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 230 245 - T 13-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 Astex_1549 b21b81443c638e3a83b8bdfd2cd6a75b 487 Gene3D G3DSA:1.10.8.60 315 394 2.0E-26 T 13-10-2018 Astex_1549 b21b81443c638e3a83b8bdfd2cd6a75b 487 Gene3D G3DSA:3.40.50.2300 1 129 6.4E-33 T 13-10-2018 Astex_1549 b21b81443c638e3a83b8bdfd2cd6a75b 487 Gene3D G3DSA:3.40.50.300 130 314 2.3E-63 T 13-10-2018 Astex_1549 b21b81443c638e3a83b8bdfd2cd6a75b 487 SMART SM00448 3 115 7.9E-38 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1549 b21b81443c638e3a83b8bdfd2cd6a75b 487 Pfam PF00072 Response regulator receiver domain 5 115 1.2E-27 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1146 b455a10fdffd87564ac9eb2b7548f87f 370 SUPERFAMILY SSF52540 3 308 5.83E-75 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1146 b455a10fdffd87564ac9eb2b7548f87f 370 PIRSF PIRSF006641 1 370 1.3E-148 T 13-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 Astex_1146 b455a10fdffd87564ac9eb2b7548f87f 370 Pfam PF06071 Protein of unknown function (DUF933) 286 369 3.7E-40 T 13-10-2018 IPR013029 YchF, C-terminal domain Reactome: R-HSA-114608 Astex_1146 b455a10fdffd87564ac9eb2b7548f87f 370 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 370 41.666 T 13-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 Astex_1146 b455a10fdffd87564ac9eb2b7548f87f 370 SUPERFAMILY SSF81271 286 367 4.58E-36 T 13-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 Astex_1146 b455a10fdffd87564ac9eb2b7548f87f 370 Pfam PF01926 50S ribosome-binding GTPase 4 116 4.1E-24 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Astex_1146 b455a10fdffd87564ac9eb2b7548f87f 370 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 370 3.7E-144 T 13-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 Astex_1146 b455a10fdffd87564ac9eb2b7548f87f 370 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 1.5E-33 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Astex_1146 b455a10fdffd87564ac9eb2b7548f87f 370 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 88 106 1.5E-33 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Astex_1146 b455a10fdffd87564ac9eb2b7548f87f 370 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 27 45 1.5E-33 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Astex_1146 b455a10fdffd87564ac9eb2b7548f87f 370 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 71 86 1.5E-33 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Astex_1146 b455a10fdffd87564ac9eb2b7548f87f 370 Gene3D G3DSA:3.40.50.300 3 285 4.0E-145 T 13-10-2018 Astex_1146 b455a10fdffd87564ac9eb2b7548f87f 370 Gene3D G3DSA:1.10.150.300 114 206 4.0E-145 T 13-10-2018 IPR023192 TGS-like domain superfamily Reactome: R-HSA-114608 Astex_1146 b455a10fdffd87564ac9eb2b7548f87f 370 Gene3D G3DSA:3.10.20.30 49 368 4.0E-145 T 13-10-2018 IPR012675 Beta-grasp domain superfamily Astex_1520 3d75f8d9b457fd09945547ceb3cb634e 301 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 270 278 - T 13-10-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Astex_1520 3d75f8d9b457fd09945547ceb3cb634e 301 SUPERFAMILY SSF53223 6 124 3.64E-37 T 13-10-2018 Astex_1520 3d75f8d9b457fd09945547ceb3cb634e 301 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 78 103 - T 13-10-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Astex_1520 3d75f8d9b457fd09945547ceb3cb634e 301 Gene3D G3DSA:3.40.50.10860 10 286 1.3E-100 T 13-10-2018 Astex_1520 3d75f8d9b457fd09945547ceb3cb634e 301 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 7 123 1.1E-35 T 13-10-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Astex_1520 3d75f8d9b457fd09945547ceb3cb634e 301 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 126 292 1.5E-63 T 13-10-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Astex_1520 3d75f8d9b457fd09945547ceb3cb634e 301 SUPERFAMILY SSF51735 125 292 2.87E-47 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_1520 3d75f8d9b457fd09945547ceb3cb634e 301 Gene3D G3DSA:3.40.50.720 8 269 1.3E-100 T 13-10-2018 Astex_1520 3d75f8d9b457fd09945547ceb3cb634e 301 Hamap MF_01576 Bifunctional protein FolD [folD]. 5 293 37.057 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Astex_1520 3d75f8d9b457fd09945547ceb3cb634e 301 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 77 104 1.5E-77 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Astex_1520 3d75f8d9b457fd09945547ceb3cb634e 301 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 211 240 1.5E-77 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Astex_1520 3d75f8d9b457fd09945547ceb3cb634e 301 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 266 284 1.5E-77 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Astex_1520 3d75f8d9b457fd09945547ceb3cb634e 301 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 36 58 1.5E-77 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Astex_1520 3d75f8d9b457fd09945547ceb3cb634e 301 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 112 133 1.5E-77 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Astex_1520 3d75f8d9b457fd09945547ceb3cb634e 301 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 162 182 1.5E-77 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Astex_1520 3d75f8d9b457fd09945547ceb3cb634e 301 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 249 265 1.5E-77 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 Astex_3764 6323acc68031d8cf966a7668a849fdad 127 SUPERFAMILY SSF50118 8 110 1.59E-25 T 13-10-2018 Astex_3764 6323acc68031d8cf966a7668a849fdad 127 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 12 107 1.5E-21 T 13-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 Astex_3764 6323acc68031d8cf966a7668a849fdad 127 Gene3D G3DSA:2.30.30.110 5 119 2.0E-33 T 13-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor Astex_0491 7cf68cf6204d95ea98b837b2c719fe90 367 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 12 366 54.048 T 13-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 Astex_0491 7cf68cf6204d95ea98b837b2c719fe90 367 SUPERFAMILY SSF53383 31 365 3.13E-73 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Astex_0491 7cf68cf6204d95ea98b837b2c719fe90 367 Gene3D G3DSA:3.90.1150.10 20 359 8.5E-100 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Astex_0491 7cf68cf6204d95ea98b837b2c719fe90 367 Gene3D G3DSA:3.40.640.10 48 272 8.5E-100 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Astex_0491 7cf68cf6204d95ea98b837b2c719fe90 367 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 17 363 4.9E-90 T 13-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 Astex_0491 7cf68cf6204d95ea98b837b2c719fe90 367 Pfam PF00155 Aminotransferase class I and II 37 358 1.8E-53 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Astex_1891 c698fb460234ef14c3b8875e6a7675be 307 Pfam PF00480 ROK family 3 306 6.5E-77 T 13-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 Astex_1891 c698fb460234ef14c3b8875e6a7675be 307 ProSitePatterns PS01125 ROK family signature. 138 165 - T 13-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 Astex_1891 c698fb460234ef14c3b8875e6a7675be 307 SUPERFAMILY SSF53067 1 306 1.46E-65 T 13-10-2018 Astex_1891 c698fb460234ef14c3b8875e6a7675be 307 Gene3D G3DSA:3.30.420.40 127 294 3.4E-84 T 13-10-2018 Astex_1891 c698fb460234ef14c3b8875e6a7675be 307 Gene3D G3DSA:3.30.420.40 5 301 3.4E-84 T 13-10-2018 Astex_0192 1e5295170efea5c8ad2387632781e580 253 SUPERFAMILY SSF75217 16 245 6.08E-82 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases Astex_0192 1e5295170efea5c8ad2387632781e580 253 Gene3D G3DSA:3.40.1280.10 13 182 1.2E-55 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Astex_0192 1e5295170efea5c8ad2387632781e580 253 Gene3D G3DSA:1.10.1270.20 183 247 7.3E-28 T 13-10-2018 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 Astex_0192 1e5295170efea5c8ad2387632781e580 253 PIRSF PIRSF000386 16 253 1.1E-82 T 13-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 Astex_0192 1e5295170efea5c8ad2387632781e580 253 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 17 245 4.2E-74 T 13-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 Astex_0192 1e5295170efea5c8ad2387632781e580 253 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 253 94.277 T 13-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 Astex_0192 1e5295170efea5c8ad2387632781e580 253 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 42 234 5.1E-52 T 13-10-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 Astex_2263 9d42c0868a165323eaf6cb2031d09246 284 Gene3D G3DSA:3.40.50.1860 4 276 1.6E-66 T 13-10-2018 Astex_2263 9d42c0868a165323eaf6cb2031d09246 284 SUPERFAMILY SSF53681 2 112 6.76E-28 T 13-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 Astex_2263 9d42c0868a165323eaf6cb2031d09246 284 SUPERFAMILY SSF53681 132 281 1.42E-20 T 13-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 Astex_2263 9d42c0868a165323eaf6cb2031d09246 284 Gene3D G3DSA:3.40.50.1860 103 230 1.6E-66 T 13-10-2018 Astex_2263 9d42c0868a165323eaf6cb2031d09246 284 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 68 76 - T 13-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 Astex_2263 9d42c0868a165323eaf6cb2031d09246 284 Hamap MF_00258 Glutamate racemase [murI]. 2 278 26.398 T 13-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 Astex_2263 9d42c0868a165323eaf6cb2031d09246 284 Pfam PF01177 Asp/Glu/Hydantoin racemase 4 237 2.7E-21 T 13-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 Astex_1979 4c70a4f3ed082f4904c03f93c624b295 464 Gene3D G3DSA:3.30.1330.90 10 159 1.9E-45 T 13-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 Astex_1979 4c70a4f3ed082f4904c03f93c624b295 464 Pfam PF03313 Serine dehydratase alpha chain 190 458 8.8E-96 T 13-10-2018 IPR005130 Serine dehydratase-like, alpha subunit Astex_1979 4c70a4f3ed082f4904c03f93c624b295 464 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 3 461 1.6E-183 T 13-10-2018 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 Astex_1979 4c70a4f3ed082f4904c03f93c624b295 464 SUPERFAMILY SSF143548 16 155 1.07E-38 T 13-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 Astex_1979 4c70a4f3ed082f4904c03f93c624b295 464 Pfam PF03315 Serine dehydratase beta chain 3 155 3.1E-49 T 13-10-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 Astex_0645 b264ae9bc475eadf707f854b04a47dd5 325 SUPERFAMILY SSF53474 60 323 5.96E-29 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_0645 b264ae9bc475eadf707f854b04a47dd5 325 PIRSF PIRSF031982 1 325 1.5E-87 T 13-10-2018 IPR016986 Uncharacterised conserved protein UCP031982, alpha/beta hydrolase, XabL Astex_0645 b264ae9bc475eadf707f854b04a47dd5 325 Pfam PF00326 Prolyl oligopeptidase family 98 176 1.6E-6 T 13-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 Astex_2891 f3c6e1fa5f689c99bd2b5997b267aab8 283 SUPERFAMILY SSF52821 5 148 4.19E-39 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily Astex_2891 f3c6e1fa5f689c99bd2b5997b267aab8 283 SMART SM00450 5 127 4.2E-21 T 13-10-2018 IPR001763 Rhodanese-like domain Astex_2891 f3c6e1fa5f689c99bd2b5997b267aab8 283 SMART SM00450 150 270 1.6E-19 T 13-10-2018 IPR001763 Rhodanese-like domain Astex_2891 f3c6e1fa5f689c99bd2b5997b267aab8 283 SUPERFAMILY SSF52821 143 277 1.1E-32 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily Astex_2891 f3c6e1fa5f689c99bd2b5997b267aab8 283 Gene3D G3DSA:3.40.250.10 4 138 3.9E-45 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily Astex_2891 f3c6e1fa5f689c99bd2b5997b267aab8 283 ProSitePatterns PS00683 Rhodanese C-terminal signature. 254 264 - T 13-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 Astex_2891 f3c6e1fa5f689c99bd2b5997b267aab8 283 Gene3D G3DSA:3.40.250.10 155 277 5.6E-39 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily Astex_2891 f3c6e1fa5f689c99bd2b5997b267aab8 283 Pfam PF00581 Rhodanese-like domain 7 123 2.7E-15 T 13-10-2018 IPR001763 Rhodanese-like domain Astex_2891 f3c6e1fa5f689c99bd2b5997b267aab8 283 Pfam PF00581 Rhodanese-like domain 155 266 7.4E-10 T 13-10-2018 IPR001763 Rhodanese-like domain Astex_3626 91cb4673b6c33301016628149400e27e 613 Gene3D G3DSA:3.20.20.70 272 517 1.5E-74 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_3626 91cb4673b6c33301016628149400e27e 613 Pfam PF14509 Glycosyl-hydrolase 97 C-terminal, oligomerisation 517 610 2.2E-22 T 13-10-2018 IPR029483 Glycosyl-hydrolase 97, C-terminal oligomerisation domain Astex_3626 91cb4673b6c33301016628149400e27e 613 Pfam PF10566 Glycoside hydrolase 97 278 515 6.4E-55 T 13-10-2018 IPR019563 Glycosyl-hydrolase 97, catalytic domain Astex_3626 91cb4673b6c33301016628149400e27e 613 Gene3D G3DSA:2.70.98.10 18 267 3.0E-29 T 13-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 Astex_3626 91cb4673b6c33301016628149400e27e 613 Gene3D G3DSA:2.60.40.1180 518 611 2.1E-19 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta Astex_3626 91cb4673b6c33301016628149400e27e 613 SUPERFAMILY SSF51445 295 493 8.0E-17 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_3626 91cb4673b6c33301016628149400e27e 613 Pfam PF14508 Glycosyl-hydrolase 97 N-terminal 32 267 1.4E-43 T 13-10-2018 IPR029486 Glycosyl-hydrolase 97, N-terminal domain Astex_0942 18edc2a8ca88f67ee61c611bff9aeac7 291 SUPERFAMILY SSF55136 137 285 2.88E-20 T 13-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily Astex_0942 18edc2a8ca88f67ee61c611bff9aeac7 291 Pfam PF12833 Helix-turn-helix domain 39 113 8.0E-12 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Astex_0942 18edc2a8ca88f67ee61c611bff9aeac7 291 Pfam PF06445 GyrI-like small molecule binding domain 137 285 1.3E-22 T 13-10-2018 IPR029442 GyrI-like small molecule binding domain Astex_0942 18edc2a8ca88f67ee61c611bff9aeac7 291 Gene3D G3DSA:3.20.80.10 136 286 1.4E-22 T 13-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily Astex_0942 18edc2a8ca88f67ee61c611bff9aeac7 291 SMART SM00342 32 112 6.8E-11 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Astex_0942 18edc2a8ca88f67ee61c611bff9aeac7 291 Gene3D G3DSA:1.10.10.60 14 115 7.2E-15 T 13-10-2018 Astex_0942 18edc2a8ca88f67ee61c611bff9aeac7 291 SMART SM00871 135 286 1.2E-15 T 13-10-2018 IPR010499 Bacterial transcription activator, effector binding Astex_3390 55d9bf2a1cef8c90559f7f162db2185c 657 Gene3D G3DSA:3.20.20.450 404 653 5.5E-86 T 13-10-2018 IPR035919 EAL domain superfamily Astex_3390 55d9bf2a1cef8c90559f7f162db2185c 657 Pfam PF00563 EAL domain 407 640 1.1E-69 T 13-10-2018 IPR001633 EAL domain Astex_3390 55d9bf2a1cef8c90559f7f162db2185c 657 SUPERFAMILY SSF141868 408 646 4.97E-78 T 13-10-2018 IPR035919 EAL domain superfamily Astex_3390 55d9bf2a1cef8c90559f7f162db2185c 657 Pfam PF00990 Diguanylate cyclase, GGDEF domain 231 386 1.8E-34 T 13-10-2018 IPR000160 GGDEF domain Astex_3390 55d9bf2a1cef8c90559f7f162db2185c 657 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 227 389 9.3E-31 T 13-10-2018 IPR000160 GGDEF domain Astex_3390 55d9bf2a1cef8c90559f7f162db2185c 657 SMART SM00267 220 391 1.9E-41 T 13-10-2018 IPR000160 GGDEF domain Astex_3390 55d9bf2a1cef8c90559f7f162db2185c 657 SMART SM00052 401 645 1.4E-98 T 13-10-2018 IPR001633 EAL domain Astex_3390 55d9bf2a1cef8c90559f7f162db2185c 657 SUPERFAMILY SSF55073 236 393 3.53E-35 T 13-10-2018 IPR029787 Nucleotide cyclase Astex_3390 55d9bf2a1cef8c90559f7f162db2185c 657 Gene3D G3DSA:3.30.70.270 225 403 4.2E-45 T 13-10-2018 Astex_3471 155e8b45c81f95239df0365cae2b7cfa 255 Pfam PF00849 RNA pseudouridylate synthase 77 213 3.2E-11 T 13-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 Astex_3471 155e8b45c81f95239df0365cae2b7cfa 255 SUPERFAMILY SSF55120 76 249 6.24E-35 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 Astex_3471 155e8b45c81f95239df0365cae2b7cfa 255 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 116 245 2.0E-38 T 13-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 Astex_3471 155e8b45c81f95239df0365cae2b7cfa 255 SMART SM00363 15 72 5.6E-10 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_3471 155e8b45c81f95239df0365cae2b7cfa 255 SUPERFAMILY SSF55174 15 127 4.58E-14 T 13-10-2018 Astex_3471 155e8b45c81f95239df0365cae2b7cfa 255 Gene3D G3DSA:3.10.290.10 13 71 4.3E-17 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 Astex_3471 155e8b45c81f95239df0365cae2b7cfa 255 Pfam PF01479 S4 domain 16 59 4.1E-11 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_3471 155e8b45c81f95239df0365cae2b7cfa 255 Gene3D G3DSA:3.30.70.580 78 248 3.6E-42 T 13-10-2018 Astex_3471 155e8b45c81f95239df0365cae2b7cfa 255 Gene3D G3DSA:3.30.70.1560 154 227 3.6E-42 T 13-10-2018 Astex_0823 f478a69e0e87566321ac20691c46ade5 365 PIRSF PIRSF019574 11 365 5.9E-98 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 Astex_0823 f478a69e0e87566321ac20691c46ade5 365 Gene3D G3DSA:3.40.190.10 148 341 7.4E-105 T 13-10-2018 Astex_0823 f478a69e0e87566321ac20691c46ade5 365 Pfam PF13416 Bacterial extracellular solute-binding protein 60 331 2.4E-38 T 13-10-2018 IPR006059 Bacterial extracellular solute-binding protein Astex_0823 f478a69e0e87566321ac20691c46ade5 365 SUPERFAMILY SSF53850 44 363 2.47E-83 T 13-10-2018 Astex_0823 f478a69e0e87566321ac20691c46ade5 365 Gene3D G3DSA:3.40.190.10 48 333 7.4E-105 T 13-10-2018 Astex_0823 f478a69e0e87566321ac20691c46ade5 365 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 266 285 2.5E-40 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 Astex_0823 f478a69e0e87566321ac20691c46ade5 365 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 92 106 2.5E-40 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 Astex_0823 f478a69e0e87566321ac20691c46ade5 365 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 311 337 2.5E-40 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 Astex_0823 f478a69e0e87566321ac20691c46ade5 365 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 108 121 2.5E-40 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 Astex_0823 f478a69e0e87566321ac20691c46ade5 365 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 222 241 2.5E-40 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 Astex_0823 f478a69e0e87566321ac20691c46ade5 365 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 185 204 2.5E-40 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 Astex_0823 f478a69e0e87566321ac20691c46ade5 365 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 139 155 2.5E-40 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 Astex_0823 f478a69e0e87566321ac20691c46ade5 365 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 49 65 2.5E-40 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 Astex_0823 f478a69e0e87566321ac20691c46ade5 365 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 65 86 2.5E-40 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 Astex_0643 b269da28d0c160dd5e5316d36877e85f 422 PIRSF PIRSF002808 1 421 2.0E-37 T 13-10-2018 IPR000849 Sugar phosphate transporter GO:0016021|GO:0022857|GO:0055085 Astex_0643 b269da28d0c160dd5e5316d36877e85f 422 Gene3D G3DSA:1.20.1250.20 221 417 5.5E-26 T 13-10-2018 Astex_0643 b269da28d0c160dd5e5316d36877e85f 422 Pfam PF07690 Major Facilitator Superfamily 17 295 2.0E-43 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Astex_0643 b269da28d0c160dd5e5316d36877e85f 422 Pfam PF07690 Major Facilitator Superfamily 301 417 1.5E-10 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Astex_0643 b269da28d0c160dd5e5316d36877e85f 422 SUPERFAMILY SSF103473 5 417 7.98E-79 T 13-10-2018 IPR036259 MFS transporter superfamily Astex_0643 b269da28d0c160dd5e5316d36877e85f 422 Gene3D G3DSA:1.20.1250.20 3 196 1.4E-43 T 13-10-2018 Astex_1693 64a221d2e5a7510d22b48e5fdba01ad7 763 Pfam PF00563 EAL domain 503 745 2.1E-70 T 13-10-2018 IPR001633 EAL domain Astex_1693 64a221d2e5a7510d22b48e5fdba01ad7 763 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 45 154 4.2E-16 T 13-10-2018 IPR000014 PAS domain Astex_1693 64a221d2e5a7510d22b48e5fdba01ad7 763 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 321 483 6.2E-40 T 13-10-2018 IPR000160 GGDEF domain Astex_1693 64a221d2e5a7510d22b48e5fdba01ad7 763 Pfam PF13426 PAS domain 49 150 1.1E-14 T 13-10-2018 IPR000014 PAS domain Astex_1693 64a221d2e5a7510d22b48e5fdba01ad7 763 SMART SM00052 497 750 7.0E-109 T 13-10-2018 IPR001633 EAL domain Astex_1693 64a221d2e5a7510d22b48e5fdba01ad7 763 Gene3D G3DSA:3.30.70.270 320 500 2.5E-52 T 13-10-2018 Astex_1693 64a221d2e5a7510d22b48e5fdba01ad7 763 Gene3D G3DSA:3.30.450.20 37 167 1.8E-21 T 13-10-2018 Astex_1693 64a221d2e5a7510d22b48e5fdba01ad7 763 SUPERFAMILY SSF55785 38 150 3.22E-21 T 13-10-2018 IPR035965 PAS domain superfamily Astex_1693 64a221d2e5a7510d22b48e5fdba01ad7 763 PIRSF PIRSF005925 30 752 1.3E-191 T 13-10-2018 IPR012226 Diguanylate cyclase/phosphodiesterase Astex_1693 64a221d2e5a7510d22b48e5fdba01ad7 763 Gene3D G3DSA:3.20.20.450 501 753 1.3E-91 T 13-10-2018 IPR035919 EAL domain superfamily Astex_1693 64a221d2e5a7510d22b48e5fdba01ad7 763 SUPERFAMILY SSF141868 504 747 1.06E-83 T 13-10-2018 IPR035919 EAL domain superfamily Astex_1693 64a221d2e5a7510d22b48e5fdba01ad7 763 SUPERFAMILY SSF55781 160 312 5.02E-16 T 13-10-2018 Astex_1693 64a221d2e5a7510d22b48e5fdba01ad7 763 Gene3D G3DSA:3.30.450.40 172 319 2.1E-15 T 13-10-2018 IPR029016 GAF-like domain superfamily Astex_1693 64a221d2e5a7510d22b48e5fdba01ad7 763 Pfam PF00990 Diguanylate cyclase, GGDEF domain 324 482 6.3E-44 T 13-10-2018 IPR000160 GGDEF domain Astex_1693 64a221d2e5a7510d22b48e5fdba01ad7 763 SMART SM00091 38 106 4.2E-8 T 13-10-2018 IPR000014 PAS domain Astex_1693 64a221d2e5a7510d22b48e5fdba01ad7 763 SUPERFAMILY SSF55073 329 488 1.02E-44 T 13-10-2018 IPR029787 Nucleotide cyclase Astex_1693 64a221d2e5a7510d22b48e5fdba01ad7 763 SMART SM00267 313 487 1.0E-57 T 13-10-2018 IPR000160 GGDEF domain Astex_1693 64a221d2e5a7510d22b48e5fdba01ad7 763 Pfam PF13185 GAF domain 171 307 2.8E-9 T 13-10-2018 IPR003018 GAF domain GO:0005515 Astex_1126 0e205100905d85556d5edd3d70d50949 371 Gene3D G3DSA:3.40.50.150 15 268 9.6E-71 T 13-10-2018 Astex_1126 0e205100905d85556d5edd3d70d50949 371 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 86 106 1.7E-38 T 13-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 Astex_1126 0e205100905d85556d5edd3d70d50949 371 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 221 239 1.7E-38 T 13-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 Astex_1126 0e205100905d85556d5edd3d70d50949 371 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 37 51 1.7E-38 T 13-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 Astex_1126 0e205100905d85556d5edd3d70d50949 371 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 244 264 1.7E-38 T 13-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 Astex_1126 0e205100905d85556d5edd3d70d50949 371 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 202 219 1.7E-38 T 13-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 Astex_1126 0e205100905d85556d5edd3d70d50949 371 Pfam PF01555 DNA methylase 38 260 3.7E-56 T 13-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 Astex_1126 0e205100905d85556d5edd3d70d50949 371 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 41 47 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 Astex_1126 0e205100905d85556d5edd3d70d50949 371 SUPERFAMILY SSF53335 17 267 7.29E-73 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Astex_2105 5ea5ef7e7e0b78f5ca21149a1fddfc78 247 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 46 214 2.3E-41 T 13-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 Astex_2105 5ea5ef7e7e0b78f5ca21149a1fddfc78 247 PIRSF PIRSF000857 4 242 1.3E-76 T 13-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 Astex_2105 5ea5ef7e7e0b78f5ca21149a1fddfc78 247 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 33 237 4.3E-56 T 13-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 Astex_2105 5ea5ef7e7e0b78f5ca21149a1fddfc78 247 SUPERFAMILY SSF52402 21 202 3.73E-44 T 13-10-2018 Astex_2105 5ea5ef7e7e0b78f5ca21149a1fddfc78 247 Gene3D G3DSA:3.40.50.620 7 242 6.2E-62 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Astex_0554 74d3df10446be8a3b96124f72ae0967b 279 Gene3D G3DSA:3.40.50.1820 5 278 7.5E-85 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_0554 74d3df10446be8a3b96124f72ae0967b 279 Pfam PF00561 alpha/beta hydrolase fold 27 259 6.2E-25 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Astex_0554 74d3df10446be8a3b96124f72ae0967b 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 52 67 1.6E-10 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Astex_0554 74d3df10446be8a3b96124f72ae0967b 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 96 109 1.6E-10 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Astex_0554 74d3df10446be8a3b96124f72ae0967b 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 222 236 1.6E-10 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Astex_0554 74d3df10446be8a3b96124f72ae0967b 279 SUPERFAMILY SSF53474 5 278 4.47E-61 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_0502 9d7fb543810a4cb06b1caebb2d64ccde 230 SUPERFAMILY SSF52833 81 228 4.82E-33 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Astex_0502 9d7fb543810a4cb06b1caebb2d64ccde 230 Gene3D G3DSA:3.40.30.10 60 230 1.2E-37 T 13-10-2018 Astex_0502 9d7fb543810a4cb06b1caebb2d64ccde 230 ProSitePatterns PS00194 Thioredoxin family active site. 119 137 - T 13-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 Astex_0502 9d7fb543810a4cb06b1caebb2d64ccde 230 Pfam PF00578 AhpC/TSA family 95 204 3.0E-18 T 13-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 Astex_1675 be940b77cdbecaf53d36c26707a6d615 633 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 102 589 1.2E-233 T 13-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 Astex_1675 be940b77cdbecaf53d36c26707a6d615 633 Gene3D G3DSA:1.10.8.60 324 397 3.2E-31 T 13-10-2018 Astex_1675 be940b77cdbecaf53d36c26707a6d615 633 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 190 321 2.0E-46 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Astex_1675 be940b77cdbecaf53d36c26707a6d615 633 Pfam PF01434 Peptidase family M41 382 588 6.0E-75 T 13-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 Astex_1675 be940b77cdbecaf53d36c26707a6d615 633 Gene3D G3DSA:3.40.50.300 137 323 7.7E-72 T 13-10-2018 Astex_1675 be940b77cdbecaf53d36c26707a6d615 633 SUPERFAMILY SSF52540 143 392 6.92E-74 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1675 be940b77cdbecaf53d36c26707a6d615 633 ProSitePatterns PS00674 AAA-protein family signature. 292 310 - T 13-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 Astex_1675 be940b77cdbecaf53d36c26707a6d615 633 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 1 599 37.324 T 13-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 Astex_1675 be940b77cdbecaf53d36c26707a6d615 633 SMART SM00382 185 324 1.8E-24 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_1675 be940b77cdbecaf53d36c26707a6d615 633 Pfam PF06480 FtsH Extracellular 8 106 4.2E-6 T 13-10-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 Astex_1675 be940b77cdbecaf53d36c26707a6d615 633 Gene3D G3DSA:1.20.58.760 398 600 6.3E-71 T 13-10-2018 Astex_1675 be940b77cdbecaf53d36c26707a6d615 633 SUPERFAMILY SSF140990 404 596 1.7E-67 T 13-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 Astex_1796 d0e185d96f00f02487c6c5553281b55f 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 29 83 1.6E-13 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Astex_1796 d0e185d96f00f02487c6c5553281b55f 236 Gene3D G3DSA:1.10.10.10 23 91 2.1E-15 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1796 d0e185d96f00f02487c6c5553281b55f 236 SMART SM00895 100 224 6.8E-13 T 13-10-2018 IPR011711 GntR, C-terminal Astex_1796 d0e185d96f00f02487c6c5553281b55f 236 SUPERFAMILY SSF46785 24 99 2.55E-13 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_1796 d0e185d96f00f02487c6c5553281b55f 236 Gene3D G3DSA:1.20.120.530 93 234 3.6E-23 T 13-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal Astex_1796 d0e185d96f00f02487c6c5553281b55f 236 SMART SM00345 31 90 2.7E-8 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Astex_1796 d0e185d96f00f02487c6c5553281b55f 236 SUPERFAMILY SSF48008 96 233 4.71E-23 T 13-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal Astex_1796 d0e185d96f00f02487c6c5553281b55f 236 Pfam PF07729 FCD domain 100 221 1.1E-21 T 13-10-2018 IPR011711 GntR, C-terminal Astex_2127 e4e05984811d3ed430f6e44c07a9a2e3 95 Pfam PF13560 Helix-turn-helix domain 13 68 2.5E-11 T 13-10-2018 Astex_2127 e4e05984811d3ed430f6e44c07a9a2e3 95 SMART SM00530 17 72 1.6E-11 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Astex_2127 e4e05984811d3ed430f6e44c07a9a2e3 95 Gene3D G3DSA:1.10.260.40 12 85 9.4E-14 T 13-10-2018 Astex_2127 e4e05984811d3ed430f6e44c07a9a2e3 95 SUPERFAMILY SSF47413 10 74 1.06E-13 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Astex_1359 35544e00808e474fd8f51d9ef14a386c 525 Gene3D G3DSA:3.30.470.30 201 397 2.1E-40 T 13-10-2018 Astex_1359 35544e00808e474fd8f51d9ef14a386c 525 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 225 233 - T 13-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 Astex_1359 35544e00808e474fd8f51d9ef14a386c 525 SUPERFAMILY SSF56091 159 398 1.64E-45 T 13-10-2018 Astex_1359 35544e00808e474fd8f51d9ef14a386c 525 Pfam PF01068 ATP dependent DNA ligase domain 204 397 1.4E-25 T 13-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 Astex_1359 35544e00808e474fd8f51d9ef14a386c 525 SUPERFAMILY SSF50249 403 520 9.59E-29 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Astex_1359 35544e00808e474fd8f51d9ef14a386c 525 Gene3D G3DSA:2.40.50.140 401 525 5.7E-29 T 13-10-2018 Astex_1359 35544e00808e474fd8f51d9ef14a386c 525 Pfam PF04679 ATP dependent DNA ligase C terminal region 418 507 5.5E-11 T 13-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 Astex_1359 35544e00808e474fd8f51d9ef14a386c 525 TIGRFAM TIGR04120 DNA_lig_bact: DNA ligase, ATP-dependent, PP_1105 family 2 521 2.7E-232 T 13-10-2018 IPR026333 ATP-dependent DNA ligase, PP_1105 family Astex_3225 15021a6f567fe0b692d9b06993787b1d 806 SUPERFAMILY SSF49303 190 293 1.58E-19 T 13-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily Astex_3225 15021a6f567fe0b692d9b06993787b1d 806 Pfam PF16355 Domain of unknown function (DUF4982) 624 683 1.1E-18 T 13-10-2018 IPR032311 Domain of unknown function DUF4982 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_3225 15021a6f567fe0b692d9b06993787b1d 806 Gene3D G3DSA:2.60.120.260 25 183 2.2E-47 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_3225 15021a6f567fe0b692d9b06993787b1d 806 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 303 454 3.8E-21 T 13-10-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 Astex_3225 15021a6f567fe0b692d9b06993787b1d 806 Gene3D G3DSA:2.60.40.10 617 695 3.9E-6 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_3225 15021a6f567fe0b692d9b06993787b1d 806 Gene3D G3DSA:2.60.40.10 696 806 6.9E-31 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_3225 15021a6f567fe0b692d9b06993787b1d 806 SUPERFAMILY SSF49785 20 184 3.83E-41 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_3225 15021a6f567fe0b692d9b06993787b1d 806 Gene3D G3DSA:2.60.40.10 184 293 8.2E-24 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_3225 15021a6f567fe0b692d9b06993787b1d 806 PRINTS PR00132 Glycosyl hydrolase family 2 signature 406 421 9.7E-12 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_3225 15021a6f567fe0b692d9b06993787b1d 806 PRINTS PR00132 Glycosyl hydrolase family 2 signature 336 354 9.7E-12 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_3225 15021a6f567fe0b692d9b06993787b1d 806 PRINTS PR00132 Glycosyl hydrolase family 2 signature 118 133 9.7E-12 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_3225 15021a6f567fe0b692d9b06993787b1d 806 PRINTS PR00132 Glycosyl hydrolase family 2 signature 305 319 9.7E-12 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_3225 15021a6f567fe0b692d9b06993787b1d 806 Pfam PF00703 Glycosyl hydrolases family 2 187 293 4.1E-15 T 13-10-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_3225 15021a6f567fe0b692d9b06993787b1d 806 SUPERFAMILY SSF51445 290 569 5.53E-59 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_3225 15021a6f567fe0b692d9b06993787b1d 806 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 34 181 2.1E-20 T 13-10-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_3225 15021a6f567fe0b692d9b06993787b1d 806 Gene3D G3DSA:3.20.20.80 296 580 1.7E-88 T 13-10-2018 Astex_1657 4d78c7880258c1eb7aa845347ace549d 342 ProSitePatterns PS00757 Prokaryotic sulfate-binding proteins signature 2. 159 167 - T 13-10-2018 IPR034408 Sulphate/thiosulphate-binding site GO:1901681 Astex_1657 4d78c7880258c1eb7aa845347ace549d 342 Pfam PF13531 Bacterial extracellular solute-binding protein 48 290 1.5E-41 T 13-10-2018 Astex_1657 4d78c7880258c1eb7aa845347ace549d 342 Gene3D G3DSA:3.40.190.10 45 305 5.2E-118 T 13-10-2018 Astex_1657 4d78c7880258c1eb7aa845347ace549d 342 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 38 335 5.9E-122 T 13-10-2018 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 Astex_1657 4d78c7880258c1eb7aa845347ace549d 342 SUPERFAMILY SSF53850 39 334 1.52E-74 T 13-10-2018 Astex_1657 4d78c7880258c1eb7aa845347ace549d 342 Gene3D G3DSA:3.40.190.10 128 334 5.2E-118 T 13-10-2018 Astex_0461 010e3f294970b7ec9ac8a689e8226277 953 TIGRFAM TIGR00593 pola: DNA polymerase I 6 953 2.0E-270 T 13-10-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Astex_0461 010e3f294970b7ec9ac8a689e8226277 953 SUPERFAMILY SSF88723 4 172 5.89E-52 T 13-10-2018 IPR029060 PIN-like domain superfamily Astex_0461 010e3f294970b7ec9ac8a689e8226277 953 PRINTS PR00868 DNA-polymerase family A (pol I) signature 676 698 3.5E-73 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Astex_0461 010e3f294970b7ec9ac8a689e8226277 953 PRINTS PR00868 DNA-polymerase family A (pol I) signature 775 800 3.5E-73 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Astex_0461 010e3f294970b7ec9ac8a689e8226277 953 PRINTS PR00868 DNA-polymerase family A (pol I) signature 896 909 3.5E-73 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Astex_0461 010e3f294970b7ec9ac8a689e8226277 953 PRINTS PR00868 DNA-polymerase family A (pol I) signature 699 714 3.5E-73 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Astex_0461 010e3f294970b7ec9ac8a689e8226277 953 PRINTS PR00868 DNA-polymerase family A (pol I) signature 721 744 3.5E-73 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Astex_0461 010e3f294970b7ec9ac8a689e8226277 953 PRINTS PR00868 DNA-polymerase family A (pol I) signature 751 764 3.5E-73 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Astex_0461 010e3f294970b7ec9ac8a689e8226277 953 PRINTS PR00868 DNA-polymerase family A (pol I) signature 812 823 3.5E-73 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Astex_0461 010e3f294970b7ec9ac8a689e8226277 953 PRINTS PR00868 DNA-polymerase family A (pol I) signature 834 845 3.5E-73 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Astex_0461 010e3f294970b7ec9ac8a689e8226277 953 PRINTS PR00868 DNA-polymerase family A (pol I) signature 866 882 3.5E-73 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Astex_0461 010e3f294970b7ec9ac8a689e8226277 953 Gene3D G3DSA:1.20.1060.10 558 679 7.3E-34 T 13-10-2018 Astex_0461 010e3f294970b7ec9ac8a689e8226277 953 ProSitePatterns PS00447 DNA polymerase family A signature. 775 794 - T 13-10-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Astex_0461 010e3f294970b7ec9ac8a689e8226277 953 Pfam PF01612 3'-5' exonuclease 339 532 2.3E-32 T 13-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 Astex_0461 010e3f294970b7ec9ac8a689e8226277 953 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 173 267 4.3E-29 T 13-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 Astex_0461 010e3f294970b7ec9ac8a689e8226277 953 SMART SM00474 339 533 3.7E-34 T 13-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 Astex_0461 010e3f294970b7ec9ac8a689e8226277 953 Gene3D G3DSA:1.10.150.20 730 873 3.9E-101 T 13-10-2018 Astex_0461 010e3f294970b7ec9ac8a689e8226277 953 SMART SM00475 4 264 6.4E-123 T 13-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 Astex_0461 010e3f294970b7ec9ac8a689e8226277 953 SMART SM00482 707 913 1.1E-110 T 13-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Astex_0461 010e3f294970b7ec9ac8a689e8226277 953 Gene3D G3DSA:3.30.420.10 335 556 8.3E-58 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Astex_0461 010e3f294970b7ec9ac8a689e8226277 953 Gene3D G3DSA:3.30.70.370 685 949 3.9E-101 T 13-10-2018 Astex_0461 010e3f294970b7ec9ac8a689e8226277 953 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 5 172 5.5E-54 T 13-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 Astex_0461 010e3f294970b7ec9ac8a689e8226277 953 SUPERFAMILY SSF56672 535 953 3.78E-141 T 13-10-2018 Astex_0461 010e3f294970b7ec9ac8a689e8226277 953 SMART SM00279 175 210 3.3E-10 T 13-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 Astex_0461 010e3f294970b7ec9ac8a689e8226277 953 SUPERFAMILY SSF53098 336 533 4.3E-45 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily Astex_0461 010e3f294970b7ec9ac8a689e8226277 953 Gene3D G3DSA:3.40.50.1010 6 280 8.8E-91 T 13-10-2018 Astex_0461 010e3f294970b7ec9ac8a689e8226277 953 Pfam PF00476 DNA polymerase family A 567 951 6.6E-140 T 13-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Astex_0461 010e3f294970b7ec9ac8a689e8226277 953 SUPERFAMILY SSF47807 173 288 3.74E-30 T 13-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily Astex_0461 010e3f294970b7ec9ac8a689e8226277 953 Gene3D G3DSA:1.10.150.20 176 249 8.8E-91 T 13-10-2018 Astex_2157 736a8dbb48c6893569e873f0270a0895 398 Pfam PF07470 Glycosyl Hydrolase Family 88 57 394 6.0E-92 T 13-10-2018 IPR010905 Glycosyl hydrolase, family 88 Astex_2157 736a8dbb48c6893569e873f0270a0895 398 SUPERFAMILY SSF48208 54 394 6.8E-81 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 Astex_2157 736a8dbb48c6893569e873f0270a0895 398 Gene3D G3DSA:1.50.10.10 21 398 2.9E-141 T 13-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 Astex_3400 d2694607ef6dd09546f198734ac8dc17 1060 SUPERFAMILY SSF51445 364 658 3.12E-78 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_3400 d2694607ef6dd09546f198734ac8dc17 1060 Gene3D G3DSA:2.60.40.10 662 767 2.0E-17 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_3400 d2694607ef6dd09546f198734ac8dc17 1060 SMART SM01038 785 1056 5.1E-83 T 13-10-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_3400 d2694607ef6dd09546f198734ac8dc17 1060 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 91 257 3.9E-33 T 13-10-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_3400 d2694607ef6dd09546f198734ac8dc17 1060 PRINTS PR00132 Glycosyl hydrolase family 2 signature 185 200 1.5E-30 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_3400 d2694607ef6dd09546f198734ac8dc17 1060 PRINTS PR00132 Glycosyl hydrolase family 2 signature 404 422 1.5E-30 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_3400 d2694607ef6dd09546f198734ac8dc17 1060 PRINTS PR00132 Glycosyl hydrolase family 2 signature 373 387 1.5E-30 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_3400 d2694607ef6dd09546f198734ac8dc17 1060 PRINTS PR00132 Glycosyl hydrolase family 2 signature 564 579 1.5E-30 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_3400 d2694607ef6dd09546f198734ac8dc17 1060 PRINTS PR00132 Glycosyl hydrolase family 2 signature 485 500 1.5E-30 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_3400 d2694607ef6dd09546f198734ac8dc17 1060 SUPERFAMILY SSF74650 773 1058 2.83E-67 T 13-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 Astex_3400 d2694607ef6dd09546f198734ac8dc17 1060 SUPERFAMILY SSF49785 51 258 1.46E-56 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_3400 d2694607ef6dd09546f198734ac8dc17 1060 Gene3D G3DSA:3.20.20.80 363 658 1.3E-97 T 13-10-2018 Astex_3400 d2694607ef6dd09546f198734ac8dc17 1060 Gene3D G3DSA:2.60.40.10 261 362 1.2E-18 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_3400 d2694607ef6dd09546f198734ac8dc17 1060 SUPERFAMILY SSF49303 259 362 6.83E-18 T 13-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily Astex_3400 d2694607ef6dd09546f198734ac8dc17 1060 Gene3D G3DSA:2.60.120.260 47 258 9.7E-78 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_3400 d2694607ef6dd09546f198734ac8dc17 1060 SUPERFAMILY SSF49303 655 765 1.51E-16 T 13-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily Astex_3400 d2694607ef6dd09546f198734ac8dc17 1060 Pfam PF16353 Domain of unknown function(DUF4981) 672 762 7.3E-13 T 13-10-2018 IPR032312 Beta-galactosidase, domain 4 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_3400 d2694607ef6dd09546f198734ac8dc17 1060 Gene3D G3DSA:2.70.98.10 789 1060 2.6E-70 T 13-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 Astex_3400 d2694607ef6dd09546f198734ac8dc17 1060 Pfam PF00703 Glycosyl hydrolases family 2 260 362 1.5E-9 T 13-10-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_3400 d2694607ef6dd09546f198734ac8dc17 1060 Pfam PF02929 Beta galactosidase small chain 790 1055 1.1E-58 T 13-10-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_3400 d2694607ef6dd09546f198734ac8dc17 1060 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 364 661 3.4E-90 T 13-10-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 Astex_3319 c1381851454a0ebad325511457cbab37 652 Gene3D G3DSA:2.60.120.1060 523 650 4.7E-24 T 13-10-2018 IPR038637 NPCBM domain superfamily Astex_3319 c1381851454a0ebad325511457cbab37 652 SMART SM00776 512 652 1.1E-10 T 13-10-2018 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module Astex_3319 c1381851454a0ebad325511457cbab37 652 Pfam PF08305 NPCBM/NEW2 domain 526 650 4.4E-26 T 13-10-2018 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module Astex_3319 c1381851454a0ebad325511457cbab37 652 Pfam PF16499 Alpha galactosidase A 57 209 4.3E-15 T 13-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Astex_3319 c1381851454a0ebad325511457cbab37 652 Pfam PF16499 Alpha galactosidase A 284 383 3.6E-14 T 13-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Astex_3319 c1381851454a0ebad325511457cbab37 652 SUPERFAMILY SSF51445 50 383 9.13E-72 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_3319 c1381851454a0ebad325511457cbab37 652 Gene3D G3DSA:3.20.20.70 49 385 6.0E-88 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_3319 c1381851454a0ebad325511457cbab37 652 SUPERFAMILY SSF49785 484 650 1.15E-30 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_3319 c1381851454a0ebad325511457cbab37 652 SUPERFAMILY SSF51011 378 472 1.78E-9 T 13-10-2018 Astex_3319 c1381851454a0ebad325511457cbab37 652 Gene3D G3DSA:2.60.40.1180 386 475 5.5E-11 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta Astex_3319 c1381851454a0ebad325511457cbab37 652 PRINTS PR00740 Glycosyl hydrolase family 27 signature 52 71 1.2E-15 T 13-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Astex_3319 c1381851454a0ebad325511457cbab37 652 PRINTS PR00740 Glycosyl hydrolase family 27 signature 88 103 1.2E-15 T 13-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Astex_3319 c1381851454a0ebad325511457cbab37 652 PRINTS PR00740 Glycosyl hydrolase family 27 signature 339 360 1.2E-15 T 13-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Astex_2815 2a9698a659f9bc1888b5f573820eccd5 690 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 3 684 7.1E-262 T 13-10-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2815 2a9698a659f9bc1888b5f573820eccd5 690 Pfam PF06455 NADH dehydrogenase subunit 5 C-terminus 564 679 5.2E-7 T 13-10-2018 IPR010934 NADH dehydrogenase subunit 5, C-terminal GO:0008137|GO:0042773|GO:0055114 KEGG: 00190+1.6.5.3|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-5083|MetaCyc: PWY-6692|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2815 2a9698a659f9bc1888b5f573820eccd5 690 Pfam PF00361 Proton-conducting membrane transporter 134 431 1.3E-88 T 13-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2815 2a9698a659f9bc1888b5f573820eccd5 690 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 66 122 1.5E-23 T 13-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2815 2a9698a659f9bc1888b5f573820eccd5 690 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 435 454 4.4E-64 T 13-10-2018 Astex_2815 2a9698a659f9bc1888b5f573820eccd5 690 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 233 254 4.4E-64 T 13-10-2018 Astex_2815 2a9698a659f9bc1888b5f573820eccd5 690 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 83 108 4.4E-64 T 13-10-2018 Astex_2815 2a9698a659f9bc1888b5f573820eccd5 690 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 158 179 4.4E-64 T 13-10-2018 Astex_2815 2a9698a659f9bc1888b5f573820eccd5 690 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 255 281 4.4E-64 T 13-10-2018 Astex_2815 2a9698a659f9bc1888b5f573820eccd5 690 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 323 335 4.4E-64 T 13-10-2018 Astex_2815 2a9698a659f9bc1888b5f573820eccd5 690 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 111 131 4.4E-64 T 13-10-2018 Astex_2815 2a9698a659f9bc1888b5f573820eccd5 690 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 434 456 1.5E-11 T 13-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 Astex_2815 2a9698a659f9bc1888b5f573820eccd5 690 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 85 105 1.5E-11 T 13-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 Astex_2815 2a9698a659f9bc1888b5f573820eccd5 690 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 273 295 1.5E-11 T 13-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 Astex_2815 2a9698a659f9bc1888b5f573820eccd5 690 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 508 529 1.5E-11 T 13-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 Astex_3784 ce43bf953f85dacc87f1f019197f75a0 199 Pfam PF05309 TraE protein 1 179 1.2E-46 T 13-10-2018 IPR007973 Pilus assembly TraE GO:0000746 Astex_1282 ccebf748082cc678169dcd2f617cfe8c 315 Gene3D G3DSA:2.120.10.30 25 307 5.2E-88 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like Astex_1282 ccebf748082cc678169dcd2f617cfe8c 315 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 259 277 1.1E-29 T 13-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) Astex_1282 ccebf748082cc678169dcd2f617cfe8c 315 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 39 56 1.1E-29 T 13-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) Astex_1282 ccebf748082cc678169dcd2f617cfe8c 315 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 155 177 1.1E-29 T 13-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) Astex_1282 ccebf748082cc678169dcd2f617cfe8c 315 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 114 135 1.1E-29 T 13-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) Astex_1282 ccebf748082cc678169dcd2f617cfe8c 315 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 178 198 1.1E-29 T 13-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) Astex_1282 ccebf748082cc678169dcd2f617cfe8c 315 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 217 234 1.1E-29 T 13-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) Astex_1282 ccebf748082cc678169dcd2f617cfe8c 315 SUPERFAMILY SSF63829 33 280 8.67E-63 T 13-10-2018 Astex_1282 ccebf748082cc678169dcd2f617cfe8c 315 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 38 277 2.3E-76 T 13-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region Astex_0969 648cb17dc5c82db7ae27200a103afeee 338 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 28 318 3.3E-115 T 13-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Astex_0969 648cb17dc5c82db7ae27200a103afeee 338 Gene3D G3DSA:3.30.1360.10 22 227 2.7E-82 T 13-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Astex_0969 648cb17dc5c82db7ae27200a103afeee 338 SMART SM00662 26 233 1.2E-90 T 13-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Astex_0969 648cb17dc5c82db7ae27200a103afeee 338 Gene3D G3DSA:1.10.150.20 247 330 3.7E-37 T 13-10-2018 Astex_0969 648cb17dc5c82db7ae27200a103afeee 338 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 258 329 2.0E-33 T 13-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Astex_0969 648cb17dc5c82db7ae27200a103afeee 338 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 32 227 5.3E-22 T 13-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Astex_0969 648cb17dc5c82db7ae27200a103afeee 338 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 6 318 35.92 T 13-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Astex_0969 648cb17dc5c82db7ae27200a103afeee 338 SUPERFAMILY SSF55257 6 231 7.38E-29 T 13-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Astex_0969 648cb17dc5c82db7ae27200a103afeee 338 SUPERFAMILY SSF47789 251 327 1.2E-27 T 13-10-2018 Astex_0969 648cb17dc5c82db7ae27200a103afeee 338 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 252 309 1.5E-25 T 13-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Astex_0969 648cb17dc5c82db7ae27200a103afeee 338 Gene3D G3DSA:2.170.120.12 56 176 2.7E-82 T 13-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Astex_0969 648cb17dc5c82db7ae27200a103afeee 338 SUPERFAMILY SSF56553 56 177 3.66E-42 T 13-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Astex_0969 648cb17dc5c82db7ae27200a103afeee 338 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 63 158 2.5E-22 T 13-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Astex_3442 3314686e331e3113f8a7141e36d69465 498 TIGRFAM TIGR00780 ccoN: cytochrome c oxidase, cbb3-type, subunit I 23 485 6.1E-223 T 13-10-2018 IPR004677 Cytochrome c oxidase cbb3-type, subunit I GO:0004129|GO:0045278|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 Astex_3442 3314686e331e3113f8a7141e36d69465 498 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 27 458 1.4E-116 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_3442 3314686e331e3113f8a7141e36d69465 498 Gene3D G3DSA:1.20.210.10 16 487 3.2E-192 T 13-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_3442 3314686e331e3113f8a7141e36d69465 498 SUPERFAMILY SSF81442 22 482 6.15E-123 T 13-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_3442 3314686e331e3113f8a7141e36d69465 498 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 218 273 - T 13-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_1168 a41cac1b5b2d559f996b8e4ab7b2948d 327 Gene3D G3DSA:3.40.50.1820 17 327 9.9E-62 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1168 a41cac1b5b2d559f996b8e4ab7b2948d 327 PIRSF PIRSF000443 2 327 6.9E-51 T 13-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 Astex_1168 a41cac1b5b2d559f996b8e4ab7b2948d 327 Pfam PF00561 alpha/beta hydrolase fold 109 313 8.4E-17 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Astex_1168 a41cac1b5b2d559f996b8e4ab7b2948d 327 SUPERFAMILY SSF53474 18 326 6.79E-48 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1132 7e02d8c986fe731d0319c299c8b51f92 441 Gene3D G3DSA:3.20.20.140 56 363 4.8E-120 T 13-10-2018 Astex_1132 7e02d8c986fe731d0319c299c8b51f92 441 SUPERFAMILY SSF51338 4 428 1.09E-30 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Astex_1132 7e02d8c986fe731d0319c299c8b51f92 441 SUPERFAMILY SSF51556 56 367 6.81E-88 T 13-10-2018 IPR032466 Metal-dependent hydrolase Astex_1132 7e02d8c986fe731d0319c299c8b51f92 441 Gene3D G3DSA:2.30.40.10 7 427 4.8E-120 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Astex_1132 7e02d8c986fe731d0319c299c8b51f92 441 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 21 423 2.1E-92 T 13-10-2018 Astex_1132 7e02d8c986fe731d0319c299c8b51f92 441 Pfam PF01979 Amidohydrolase family 53 420 9.0E-22 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 Astex_1132 7e02d8c986fe731d0319c299c8b51f92 441 ProSitePatterns PS00483 Dihydroorotase signature 2. 302 313 - T 13-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Astex_1213 b77d69afc9a69a7e49f62d9f24ec59ae 596 SMART SM00388 234 300 6.4E-8 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_1213 b77d69afc9a69a7e49f62d9f24ec59ae 596 Gene3D G3DSA:3.30.565.10 301 458 5.1E-44 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_1213 b77d69afc9a69a7e49f62d9f24ec59ae 596 Pfam PF00072 Response regulator receiver domain 475 584 2.6E-16 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1213 b77d69afc9a69a7e49f62d9f24ec59ae 596 SUPERFAMILY SSF55874 290 451 6.55E-41 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_1213 b77d69afc9a69a7e49f62d9f24ec59ae 596 SMART SM00387 341 453 3.3E-28 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_1213 b77d69afc9a69a7e49f62d9f24ec59ae 596 SMART SM00448 473 584 5.8E-17 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1213 b77d69afc9a69a7e49f62d9f24ec59ae 596 SUPERFAMILY SSF52172 472 591 1.99E-25 T 13-10-2018 IPR011006 CheY-like superfamily Astex_1213 b77d69afc9a69a7e49f62d9f24ec59ae 596 SMART SM00091 102 171 0.0044 T 13-10-2018 IPR000014 PAS domain Astex_1213 b77d69afc9a69a7e49f62d9f24ec59ae 596 SMART SM00086 177 219 4.3E-8 T 13-10-2018 IPR001610 PAC motif Astex_1213 b77d69afc9a69a7e49f62d9f24ec59ae 596 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 342 451 4.2E-18 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_1213 b77d69afc9a69a7e49f62d9f24ec59ae 596 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 396 1.2E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1213 b77d69afc9a69a7e49f62d9f24ec59ae 596 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 431 1.2E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1213 b77d69afc9a69a7e49f62d9f24ec59ae 596 PRINTS PR00344 Bacterial sensor protein C-terminal signature 437 450 1.2E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1213 b77d69afc9a69a7e49f62d9f24ec59ae 596 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 410 1.2E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1213 b77d69afc9a69a7e49f62d9f24ec59ae 596 Gene3D G3DSA:3.30.450.20 101 230 1.6E-41 T 13-10-2018 Astex_1213 b77d69afc9a69a7e49f62d9f24ec59ae 596 SUPERFAMILY SSF47384 223 297 1.41E-10 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Astex_1213 b77d69afc9a69a7e49f62d9f24ec59ae 596 Gene3D G3DSA:1.10.287.130 231 298 2.6E-19 T 13-10-2018 Astex_1213 b77d69afc9a69a7e49f62d9f24ec59ae 596 SUPERFAMILY SSF55785 109 219 9.6E-27 T 13-10-2018 IPR035965 PAS domain superfamily Astex_1213 b77d69afc9a69a7e49f62d9f24ec59ae 596 Pfam PF13426 PAS domain 118 217 1.3E-19 T 13-10-2018 IPR000014 PAS domain Astex_1213 b77d69afc9a69a7e49f62d9f24ec59ae 596 Pfam PF00512 His Kinase A (phospho-acceptor) domain 236 298 2.6E-8 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_1213 b77d69afc9a69a7e49f62d9f24ec59ae 596 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 101 226 2.4E-17 T 13-10-2018 IPR000014 PAS domain Astex_1213 b77d69afc9a69a7e49f62d9f24ec59ae 596 Gene3D G3DSA:3.40.50.2300 470 595 4.7E-25 T 13-10-2018 Astex_3611 aa55a443e40bd6628215e10e1c62615d 969 Gene3D G3DSA:3.20.20.80 267 615 5.9E-100 T 13-10-2018 Astex_3611 aa55a443e40bd6628215e10e1c62615d 969 SUPERFAMILY SSF51011 615 650 3.02E-5 T 13-10-2018 Astex_3611 aa55a443e40bd6628215e10e1c62615d 969 SUPERFAMILY SSF56988 674 802 4.84E-32 T 13-10-2018 Astex_3611 aa55a443e40bd6628215e10e1c62615d 969 SUPERFAMILY SSF51011 817 858 3.17E-6 T 13-10-2018 Astex_3611 aa55a443e40bd6628215e10e1c62615d 969 SMART SM00758 672 811 5.0E-27 T 13-10-2018 IPR011658 PA14 domain Astex_3611 aa55a443e40bd6628215e10e1c62615d 969 SUPERFAMILY SSF51445 256 609 6.02E-55 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_3611 aa55a443e40bd6628215e10e1c62615d 969 SUPERFAMILY SSF74650 52 252 2.04E-27 T 13-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 Astex_3611 aa55a443e40bd6628215e10e1c62615d 969 Pfam PF17137 Domain of unknown function (DUF5110) 880 945 1.1E-19 T 13-10-2018 IPR033403 Domain of unknown function DUF5110 Astex_3611 aa55a443e40bd6628215e10e1c62615d 969 Gene3D G3DSA:2.60.40.1180 859 968 4.4E-28 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta Astex_3611 aa55a443e40bd6628215e10e1c62615d 969 Gene3D G3DSA:2.60.40.1760 48 266 2.9E-43 T 13-10-2018 Astex_3611 aa55a443e40bd6628215e10e1c62615d 969 Gene3D G3DSA:2.60.40.1180 616 664 1.1E-7 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta Astex_3611 aa55a443e40bd6628215e10e1c62615d 969 Gene3D G3DSA:2.60.40.1180 817 857 5.6E-10 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta Astex_3611 aa55a443e40bd6628215e10e1c62615d 969 Pfam PF01055 Glycosyl hydrolases family 31 247 650 4.1E-99 T 13-10-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 Astex_3611 aa55a443e40bd6628215e10e1c62615d 969 Pfam PF07691 PA14 domain 672 802 4.3E-21 T 13-10-2018 IPR011658 PA14 domain Astex_3611 aa55a443e40bd6628215e10e1c62615d 969 Pfam PF16338 Domain of unknown function (DUF4968) 56 140 5.4E-8 T 13-10-2018 IPR032513 Alpha-glucosidase, domain of unknown function DUF4968 Astex_3611 aa55a443e40bd6628215e10e1c62615d 969 Gene3D G3DSA:3.90.182.10 666 816 5.1E-20 T 13-10-2018 Astex_3611 aa55a443e40bd6628215e10e1c62615d 969 Pfam PF01055 Glycosyl hydrolases family 31 817 862 8.9E-7 T 13-10-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 Astex_0624 49b3a71ddfc98eb229114571ec06eb5c 247 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 137 245 1.4E-15 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_0624 49b3a71ddfc98eb229114571ec06eb5c 247 Gene3D G3DSA:1.10.287.130 11 91 1.2E-18 T 13-10-2018 Astex_0624 49b3a71ddfc98eb229114571ec06eb5c 247 SMART SM00388 21 90 1.2E-18 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_0624 49b3a71ddfc98eb229114571ec06eb5c 247 Pfam PF00512 His Kinase A (phospho-acceptor) domain 22 89 3.2E-15 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_0624 49b3a71ddfc98eb229114571ec06eb5c 247 SUPERFAMILY SSF47384 22 90 3.34E-16 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Astex_0624 49b3a71ddfc98eb229114571ec06eb5c 247 SMART SM00387 136 247 3.4E-15 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_0624 49b3a71ddfc98eb229114571ec06eb5c 247 SUPERFAMILY SSF55874 79 245 3.93E-26 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_0624 49b3a71ddfc98eb229114571ec06eb5c 247 Gene3D G3DSA:3.30.565.10 98 247 3.7E-24 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_1318 239d3c0ac4e0076cedd06ff1e56b3414 1126 Pfam PF00704 Glycosyl hydrolases family 18 85 373 8.9E-14 T 13-10-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 Astex_1318 239d3c0ac4e0076cedd06ff1e56b3414 1126 SUPERFAMILY SSF51445 85 381 4.67E-24 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_1318 239d3c0ac4e0076cedd06ff1e56b3414 1126 SUPERFAMILY SSF53448 753 992 6.75E-60 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_1318 239d3c0ac4e0076cedd06ff1e56b3414 1126 SMART SM00636 84 350 5.1E-5 T 13-10-2018 IPR011583 Chitinase II GO:0008061 Astex_1318 239d3c0ac4e0076cedd06ff1e56b3414 1126 Gene3D G3DSA:3.20.20.80 135 380 3.3E-43 T 13-10-2018 Astex_1318 239d3c0ac4e0076cedd06ff1e56b3414 1126 Gene3D G3DSA:3.10.50.10 294 346 3.3E-43 T 13-10-2018 IPR029070 Chitinase insertion domain superfamily Astex_1318 239d3c0ac4e0076cedd06ff1e56b3414 1126 SUPERFAMILY SSF88713 444 671 1.14E-53 T 13-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 Astex_1318 239d3c0ac4e0076cedd06ff1e56b3414 1126 Pfam PF13641 Glycosyltransferase like family 2 753 974 6.1E-36 T 13-10-2018 Astex_1318 239d3c0ac4e0076cedd06ff1e56b3414 1126 Pfam PF01522 Polysaccharide deacetylase 453 555 1.3E-26 T 13-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 Astex_1318 239d3c0ac4e0076cedd06ff1e56b3414 1126 Gene3D G3DSA:3.90.550.10 746 964 5.2E-48 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_1318 239d3c0ac4e0076cedd06ff1e56b3414 1126 Gene3D G3DSA:3.20.20.370 443 674 4.9E-61 T 13-10-2018 Astex_2191 ecedcc0470b3b2b1fed37dcfe8123b13 353 Pfam PF13692 Glycosyl transferases group 1 177 315 5.7E-27 T 13-10-2018 Astex_2191 ecedcc0470b3b2b1fed37dcfe8123b13 353 Gene3D G3DSA:3.40.50.2000 23 347 2.3E-61 T 13-10-2018 Astex_2191 ecedcc0470b3b2b1fed37dcfe8123b13 353 SUPERFAMILY SSF53756 2 349 2.27E-66 T 13-10-2018 Astex_2191 ecedcc0470b3b2b1fed37dcfe8123b13 353 Gene3D G3DSA:3.40.50.2000 158 334 2.3E-61 T 13-10-2018 Astex_2191 ecedcc0470b3b2b1fed37dcfe8123b13 353 Pfam PF13439 Glycosyltransferase Family 4 19 157 2.7E-22 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 Astex_2488 f5fe0be7d21aa3d12f2f560d8b81f236 290 Pfam PF03524 Conjugal transfer protein 55 277 5.5E-58 T 13-10-2018 IPR010258 Conjugal transfer, TrbG/VirB9/CagX Astex_2488 f5fe0be7d21aa3d12f2f560d8b81f236 290 TIGRFAM TIGR02775 TrbG_Ti: P-type conjugative transfer protein TrbG 56 265 2.1E-70 T 13-10-2018 IPR014142 P-type conjugative transfer protein TrbG Astex_2488 f5fe0be7d21aa3d12f2f560d8b81f236 290 Gene3D G3DSA:2.60.40.2500 181 279 5.5E-8 T 13-10-2018 IPR038161 VirB9/CagX/TrbG, C-terminal domain superfamily Astex_1668 1d09cef5ed98ed51bc95ae36de7c54ee 697 Pfam PF12826 Helix-hairpin-helix motif 529 598 2.9E-7 T 13-10-2018 Astex_1668 1d09cef5ed98ed51bc95ae36de7c54ee 697 SUPERFAMILY SSF50249 324 406 2.57E-26 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Astex_1668 1d09cef5ed98ed51bc95ae36de7c54ee 697 SMART SM00278 531 550 17.0 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 Astex_1668 1d09cef5ed98ed51bc95ae36de7c54ee 697 SMART SM00278 573 592 540.0 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 Astex_1668 1d09cef5ed98ed51bc95ae36de7c54ee 697 SMART SM00278 459 478 640.0 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 Astex_1668 1d09cef5ed98ed51bc95ae36de7c54ee 697 SMART SM00278 499 518 430.0 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 Astex_1668 1d09cef5ed98ed51bc95ae36de7c54ee 697 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 329 404 3.8E-33 T 13-10-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 Astex_1668 1d09cef5ed98ed51bc95ae36de7c54ee 697 SUPERFAMILY SSF56091 6 323 1.76E-113 T 13-10-2018 Astex_1668 1d09cef5ed98ed51bc95ae36de7c54ee 697 Gene3D G3DSA:2.40.50.140 326 412 3.6E-35 T 13-10-2018 Astex_1668 1d09cef5ed98ed51bc95ae36de7c54ee 697 Hamap MF_01588 DNA ligase [ligA]. 7 694 48.357 T 13-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 Astex_1668 1d09cef5ed98ed51bc95ae36de7c54ee 697 Gene3D G3DSA:1.10.150.20 445 524 2.6E-23 T 13-10-2018 Astex_1668 1d09cef5ed98ed51bc95ae36de7c54ee 697 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 624 692 1.2E-10 T 13-10-2018 IPR001357 BRCT domain Astex_1668 1d09cef5ed98ed51bc95ae36de7c54ee 697 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 122 151 - T 13-10-2018 IPR018239 NAD-dependent DNA ligase, active site Astex_1668 1d09cef5ed98ed51bc95ae36de7c54ee 697 Gene3D G3DSA:1.10.150.20 525 609 1.9E-12 T 13-10-2018 Astex_1668 1d09cef5ed98ed51bc95ae36de7c54ee 697 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 16 690 3.8E-223 T 13-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 Astex_1668 1d09cef5ed98ed51bc95ae36de7c54ee 697 Gene3D G3DSA:3.40.50.10190 610 695 1.7E-26 T 13-10-2018 IPR036420 BRCT domain superfamily Astex_1668 1d09cef5ed98ed51bc95ae36de7c54ee 697 PIRSF PIRSF001604 1 696 1.1E-224 T 13-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 Astex_1668 1d09cef5ed98ed51bc95ae36de7c54ee 697 Gene3D G3DSA:1.10.287.610 6 75 1.4E-23 T 13-10-2018 Astex_1668 1d09cef5ed98ed51bc95ae36de7c54ee 697 SUPERFAMILY SSF52113 621 694 4.49E-18 T 13-10-2018 IPR036420 BRCT domain superfamily Astex_1668 1d09cef5ed98ed51bc95ae36de7c54ee 697 SMART SM00292 620 697 1.1E-8 T 13-10-2018 IPR001357 BRCT domain Astex_1668 1d09cef5ed98ed51bc95ae36de7c54ee 697 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 9 325 7.3E-121 T 13-10-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 Astex_1668 1d09cef5ed98ed51bc95ae36de7c54ee 697 Gene3D G3DSA:3.30.470.90 76 325 2.5E-96 T 13-10-2018 Astex_1668 1d09cef5ed98ed51bc95ae36de7c54ee 697 SMART SM00532 8 461 2.4E-227 T 13-10-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 Astex_1668 1d09cef5ed98ed51bc95ae36de7c54ee 697 SUPERFAMILY SSF47781 410 606 9.45E-38 T 13-10-2018 IPR010994 RuvA domain 2-like Astex_0722 a55030133220cdb4f9325d70fcd0253c 557 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 185 210 - T 13-10-2018 IPR018212 Sodium/solute symporter, conserved site Astex_0722 a55030133220cdb4f9325d70fcd0253c 557 Gene3D G3DSA:1.20.1730.10 57 551 8.3E-59 T 13-10-2018 IPR038377 Sodium/glucose symporter superfamily Astex_0722 a55030133220cdb4f9325d70fcd0253c 557 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 70 476 2.7E-63 T 13-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 Astex_0722 a55030133220cdb4f9325d70fcd0253c 557 Pfam PF00474 Sodium:solute symporter family 70 476 2.5E-121 T 13-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 Astex_0409 42c01e1776df3ac24866392e7a8dc337 631 Gene3D G3DSA:1.10.1370.30 372 556 1.7E-5 T 13-10-2018 Astex_0409 42c01e1776df3ac24866392e7a8dc337 631 PRINTS PR00791 Peptidyl-dipeptidase A (M2) metalloprotease family signature 396 412 1.1E-75 T 13-10-2018 IPR001548 Peptidase M2, peptidyl-dipeptidase A GO:0006508|GO:0008237|GO:0008241|GO:0016020 Astex_0409 42c01e1776df3ac24866392e7a8dc337 631 PRINTS PR00791 Peptidyl-dipeptidase A (M2) metalloprotease family signature 499 526 1.1E-75 T 13-10-2018 IPR001548 Peptidase M2, peptidyl-dipeptidase A GO:0006508|GO:0008237|GO:0008241|GO:0016020 Astex_0409 42c01e1776df3ac24866392e7a8dc337 631 PRINTS PR00791 Peptidyl-dipeptidase A (M2) metalloprotease family signature 424 444 1.1E-75 T 13-10-2018 IPR001548 Peptidase M2, peptidyl-dipeptidase A GO:0006508|GO:0008237|GO:0008241|GO:0016020 Astex_0409 42c01e1776df3ac24866392e7a8dc337 631 PRINTS PR00791 Peptidyl-dipeptidase A (M2) metalloprotease family signature 251 278 1.1E-75 T 13-10-2018 IPR001548 Peptidase M2, peptidyl-dipeptidase A GO:0006508|GO:0008237|GO:0008241|GO:0016020 Astex_0409 42c01e1776df3ac24866392e7a8dc337 631 PRINTS PR00791 Peptidyl-dipeptidase A (M2) metalloprotease family signature 364 389 1.1E-75 T 13-10-2018 IPR001548 Peptidase M2, peptidyl-dipeptidase A GO:0006508|GO:0008237|GO:0008241|GO:0016020 Astex_0409 42c01e1776df3ac24866392e7a8dc337 631 PRINTS PR00791 Peptidyl-dipeptidase A (M2) metalloprotease family signature 527 555 1.1E-75 T 13-10-2018 IPR001548 Peptidase M2, peptidyl-dipeptidase A GO:0006508|GO:0008237|GO:0008241|GO:0016020 Astex_0409 42c01e1776df3ac24866392e7a8dc337 631 PRINTS PR00791 Peptidyl-dipeptidase A (M2) metalloprotease family signature 286 307 1.1E-75 T 13-10-2018 IPR001548 Peptidase M2, peptidyl-dipeptidase A GO:0006508|GO:0008237|GO:0008241|GO:0016020 Astex_0409 42c01e1776df3ac24866392e7a8dc337 631 PRINTS PR00791 Peptidyl-dipeptidase A (M2) metalloprotease family signature 464 489 1.1E-75 T 13-10-2018 IPR001548 Peptidase M2, peptidyl-dipeptidase A GO:0006508|GO:0008237|GO:0008241|GO:0016020 Astex_0409 42c01e1776df3ac24866392e7a8dc337 631 Pfam PF01401 Angiotensin-converting enzyme 59 631 1.3E-201 T 13-10-2018 IPR001548 Peptidase M2, peptidyl-dipeptidase A GO:0006508|GO:0008237|GO:0008241|GO:0016020 Astex_0409 42c01e1776df3ac24866392e7a8dc337 631 SUPERFAMILY SSF55486 59 631 4.62E-202 T 13-10-2018 Astex_1212 7418203824b60d7eef4a373b34f1a79c 582 SUPERFAMILY SSF52317 240 430 2.75E-7 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Astex_0800 4bc95b0d52a85863281eca42d864a771 345 SUPERFAMILY SSF53383 1 338 1.33E-89 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Astex_0800 4bc95b0d52a85863281eca42d864a771 345 Pfam PF01212 Beta-eliminating lyase 4 290 2.3E-53 T 13-10-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 Astex_0800 4bc95b0d52a85863281eca42d864a771 345 Gene3D G3DSA:3.90.1150.10 6 333 2.9E-117 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Astex_0800 4bc95b0d52a85863281eca42d864a771 345 Gene3D G3DSA:3.40.640.10 13 251 2.9E-117 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Astex_2851 8e40dbf1360e25d0813bc06fbb6bb784 800 Gene3D G3DSA:3.10.20.310 202 292 9.8E-22 T 13-10-2018 Astex_2851 8e40dbf1360e25d0813bc06fbb6bb784 800 TIGRFAM TIGR03303 OM_YaeT: outer membrane protein assembly complex, YaeT protein 54 800 9.1E-231 T 13-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 Astex_2851 8e40dbf1360e25d0813bc06fbb6bb784 800 PIRSF PIRSF006076 6 800 5.8E-240 T 13-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 Astex_2851 8e40dbf1360e25d0813bc06fbb6bb784 800 Gene3D G3DSA:3.10.20.310 375 450 8.0E-20 T 13-10-2018 Astex_2851 8e40dbf1360e25d0813bc06fbb6bb784 800 Gene3D G3DSA:3.10.20.310 49 120 3.2E-17 T 13-10-2018 Astex_2851 8e40dbf1360e25d0813bc06fbb6bb784 800 Gene3D G3DSA:3.10.20.310 293 369 4.3E-14 T 13-10-2018 Astex_2851 8e40dbf1360e25d0813bc06fbb6bb784 800 Gene3D G3DSA:3.10.20.310 121 199 6.9E-18 T 13-10-2018 Astex_2851 8e40dbf1360e25d0813bc06fbb6bb784 800 Pfam PF07244 Surface antigen variable number repeat 294 371 2.7E-11 T 13-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 Astex_2851 8e40dbf1360e25d0813bc06fbb6bb784 800 Pfam PF07244 Surface antigen variable number repeat 54 119 8.6E-5 T 13-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 Astex_2851 8e40dbf1360e25d0813bc06fbb6bb784 800 Pfam PF07244 Surface antigen variable number repeat 374 446 9.1E-12 T 13-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 Astex_2851 8e40dbf1360e25d0813bc06fbb6bb784 800 Pfam PF07244 Surface antigen variable number repeat 121 198 5.8E-16 T 13-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 Astex_2851 8e40dbf1360e25d0813bc06fbb6bb784 800 Pfam PF07244 Surface antigen variable number repeat 203 289 1.7E-14 T 13-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 Astex_2851 8e40dbf1360e25d0813bc06fbb6bb784 800 Hamap MF_01430 Outer membrane protein assembly factor BamA [bamA]. 16 800 23.366 T 13-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 Astex_2851 8e40dbf1360e25d0813bc06fbb6bb784 800 Pfam PF01103 Surface antigen 474 800 3.0E-71 T 13-10-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 Astex_2851 8e40dbf1360e25d0813bc06fbb6bb784 800 Gene3D G3DSA:2.40.160.50 451 800 7.6E-97 T 13-10-2018 Astex_1659 df7717fe9220ade5a74e22b0866398d9 281 Gene3D G3DSA:1.10.3720.10 14 271 2.6E-57 T 13-10-2018 IPR035906 MetI-like superfamily Astex_1659 df7717fe9220ade5a74e22b0866398d9 281 SUPERFAMILY SSF161098 13 263 1.44E-48 T 13-10-2018 IPR035906 MetI-like superfamily Astex_1659 df7717fe9220ade5a74e22b0866398d9 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 77 268 4.3E-11 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Astex_1659 df7717fe9220ade5a74e22b0866398d9 281 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 17 270 8.1E-94 T 13-10-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 Astex_1659 df7717fe9220ade5a74e22b0866398d9 281 TIGRFAM TIGR02140 permease_CysW: sulfate ABC transporter, permease protein CysW 15 271 2.0E-115 T 13-10-2018 IPR011866 Sulphate ABC transporter, permease protein CysW GO:0008272|GO:0015116|GO:0016021 Astex_0921 b72356499578aca1890202a19efbf17f 526 Gene3D G3DSA:1.20.1560.10 7 307 2.8E-10 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Astex_0921 b72356499578aca1890202a19efbf17f 526 SUPERFAMILY SSF90123 11 312 6.02E-19 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Astex_0921 b72356499578aca1890202a19efbf17f 526 Gene3D G3DSA:3.40.50.300 308 521 1.5E-39 T 13-10-2018 Astex_0921 b72356499578aca1890202a19efbf17f 526 Pfam PF00005 ABC transporter 329 470 5.5E-14 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_0921 b72356499578aca1890202a19efbf17f 526 SMART SM00382 332 518 5.2E-4 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_0921 b72356499578aca1890202a19efbf17f 526 SUPERFAMILY SSF52540 319 516 1.62E-31 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0921 b72356499578aca1890202a19efbf17f 526 ProSitePatterns PS00211 ABC transporters family signature. 443 457 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Astex_2249 6b7dcc90892bb36abb243f31ff9e65b7 191 Pfam PF13470 PIN domain 10 115 6.0E-17 T 13-10-2018 IPR002716 PIN domain Astex_2249 6b7dcc90892bb36abb243f31ff9e65b7 191 SUPERFAMILY SSF88723 10 122 1.4E-6 T 13-10-2018 IPR029060 PIN-like domain superfamily Astex_2827 d6935ae435ffe4c961337bb21b0143c5 153 Pfam PF02643 Uncharacterized ACR, COG1430 38 141 6.8E-33 T 13-10-2018 IPR003795 Protein of unknown function DUF192 Astex_2827 d6935ae435ffe4c961337bb21b0143c5 153 Gene3D G3DSA:2.60.120.1140 14 142 4.2E-44 T 13-10-2018 IPR038695 Saro_0823-like superfamily Astex_1931 200ad75d665ddf33c39ff0d9a8432e87 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Astex_1931 200ad75d665ddf33c39ff0d9a8432e87 255 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 10 192 0.0012 T 13-10-2018 Astex_1931 200ad75d665ddf33c39ff0d9a8432e87 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 2.6E-42 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1931 200ad75d665ddf33c39ff0d9a8432e87 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 2.6E-42 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1931 200ad75d665ddf33c39ff0d9a8432e87 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 2.6E-42 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1931 200ad75d665ddf33c39ff0d9a8432e87 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 2.6E-42 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1931 200ad75d665ddf33c39ff0d9a8432e87 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 2.6E-42 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1931 200ad75d665ddf33c39ff0d9a8432e87 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 2.6E-42 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1931 200ad75d665ddf33c39ff0d9a8432e87 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 251 5.6E-61 T 13-10-2018 Astex_1931 200ad75d665ddf33c39ff0d9a8432e87 255 Gene3D G3DSA:3.40.50.720 3 254 2.9E-81 T 13-10-2018 Astex_1931 200ad75d665ddf33c39ff0d9a8432e87 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 7.9E-11 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1931 200ad75d665ddf33c39ff0d9a8432e87 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 7.9E-11 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1931 200ad75d665ddf33c39ff0d9a8432e87 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 7.9E-11 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1931 200ad75d665ddf33c39ff0d9a8432e87 255 SUPERFAMILY SSF51735 8 254 7.22E-79 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_0699 88afe33aef716adceadd96958e1773fc 529 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 347 367 - T 13-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 Astex_0699 88afe33aef716adceadd96958e1773fc 529 SUPERFAMILY SSF52833 1 102 1.68E-26 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Astex_0699 88afe33aef716adceadd96958e1773fc 529 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 215 506 3.5E-45 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Astex_0699 88afe33aef716adceadd96958e1773fc 529 Pfam PF13192 Thioredoxin domain 127 197 9.8E-7 T 13-10-2018 IPR012336 Thioredoxin-like fold Astex_0699 88afe33aef716adceadd96958e1773fc 529 Gene3D G3DSA:3.50.50.60 215 510 6.1E-112 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_0699 88afe33aef716adceadd96958e1773fc 529 SUPERFAMILY SSF52833 106 199 1.32E-20 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Astex_0699 88afe33aef716adceadd96958e1773fc 529 SUPERFAMILY SSF51905 206 515 4.42E-51 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_0699 88afe33aef716adceadd96958e1773fc 529 Gene3D G3DSA:3.50.50.60 329 452 6.1E-112 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_0699 88afe33aef716adceadd96958e1773fc 529 PIRSF PIRSF000238 1 523 1.4E-258 T 13-10-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0050660|GO:0051287 Astex_0699 88afe33aef716adceadd96958e1773fc 529 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 317 335 1.7E-38 T 13-10-2018 Astex_0699 88afe33aef716adceadd96958e1773fc 529 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 470 492 1.7E-38 T 13-10-2018 Astex_0699 88afe33aef716adceadd96958e1773fc 529 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 359 377 1.7E-38 T 13-10-2018 Astex_0699 88afe33aef716adceadd96958e1773fc 529 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 444 460 1.7E-38 T 13-10-2018 Astex_0699 88afe33aef716adceadd96958e1773fc 529 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 217 236 1.7E-38 T 13-10-2018 Astex_0699 88afe33aef716adceadd96958e1773fc 529 Gene3D G3DSA:3.40.30.80 1 202 9.0E-56 T 13-10-2018 Astex_0699 88afe33aef716adceadd96958e1773fc 529 TIGRFAM TIGR03140 AhpF: alkyl hydroperoxide reductase subunit F 1 519 2.3E-237 T 13-10-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0050660|GO:0051287 Astex_0699 88afe33aef716adceadd96958e1773fc 529 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 340 352 3.3E-67 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Astex_0699 88afe33aef716adceadd96958e1773fc 529 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 318 326 3.3E-67 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Astex_0699 88afe33aef716adceadd96958e1773fc 529 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 216 238 3.3E-67 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Astex_0699 88afe33aef716adceadd96958e1773fc 529 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 248 263 3.3E-67 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Astex_0699 88afe33aef716adceadd96958e1773fc 529 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 355 379 3.3E-67 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Astex_0699 88afe33aef716adceadd96958e1773fc 529 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 446 467 3.3E-67 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Astex_0699 88afe33aef716adceadd96958e1773fc 529 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 480 498 3.3E-67 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Astex_0699 88afe33aef716adceadd96958e1773fc 529 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 407 423 3.3E-67 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Astex_0699 88afe33aef716adceadd96958e1773fc 529 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 268 278 3.3E-67 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Astex_2124 9b7127cf55f3fc3ef728d0173b244f9b 212 Pfam PF12408 Ribose-5-phosphate isomerase 164 210 3.0E-24 T 13-10-2018 IPR022133 Ribose-5-phosphate isomerase, C-terminal Astex_2124 9b7127cf55f3fc3ef728d0173b244f9b 212 SUPERFAMILY SSF89623 1 160 1.1E-35 T 13-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 Astex_2124 9b7127cf55f3fc3ef728d0173b244f9b 212 Gene3D G3DSA:3.40.1400.10 1 212 4.3E-94 T 13-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 Astex_2124 9b7127cf55f3fc3ef728d0173b244f9b 212 Pfam PF02502 Ribose/Galactose Isomerase 3 114 7.5E-27 T 13-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 Astex_1504 d19f37aeec60d1a8b0c64fdf9b54334c 228 Pfam PF07298 NnrU protein 4 223 2.7E-40 T 13-10-2018 IPR009915 NnrU domain Astex_2964 9560683e43fd0d2fbcebcc684562e865 249 Gene3D G3DSA:3.20.20.70 1 249 3.1E-90 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_2964 9560683e43fd0d2fbcebcc684562e865 249 Hamap MF_00279 Pyridoxine 5'-phosphate synthase [pdxJ]. 1 249 107.187 T 13-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 Astex_2964 9560683e43fd0d2fbcebcc684562e865 249 SUPERFAMILY SSF63892 3 247 3.14E-85 T 13-10-2018 IPR036130 Pyridoxine 5'-phosphate synthase GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 Astex_2964 9560683e43fd0d2fbcebcc684562e865 249 TIGRFAM TIGR00559 pdxJ: pyridoxine 5'-phosphate synthase 5 244 7.9E-76 T 13-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 Astex_2964 9560683e43fd0d2fbcebcc684562e865 249 Pfam PF03740 Pyridoxal phosphate biosynthesis protein PdxJ 5 244 4.8E-89 T 13-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 Astex_0379 7022217393920c1971404974a032c246 137 SUPERFAMILY SSF52172 1 122 2.85E-31 T 13-10-2018 IPR011006 CheY-like superfamily Astex_0379 7022217393920c1971404974a032c246 137 Gene3D G3DSA:3.40.50.2300 1 123 5.3E-33 T 13-10-2018 Astex_0379 7022217393920c1971404974a032c246 137 SMART SM00448 1 117 2.9E-31 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_0379 7022217393920c1971404974a032c246 137 Pfam PF00072 Response regulator receiver domain 4 117 2.9E-22 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_3074 976ff3c6b6ae3218c24e87b36ecfe417 308 SUPERFAMILY SSF51430 1 289 3.54E-13 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily Astex_3074 976ff3c6b6ae3218c24e87b36ecfe417 308 Gene3D G3DSA:3.20.20.100 1 290 1.5E-13 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily Astex_3074 976ff3c6b6ae3218c24e87b36ecfe417 308 Pfam PF00248 Aldo/keto reductase family 28 289 1.2E-6 T 13-10-2018 IPR023210 NADP-dependent oxidoreductase domain Astex_1269 8b4fb16b3eec094b28475edc2f586d44 216 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 12 211 4.7E-55 T 13-10-2018 Astex_1269 8b4fb16b3eec094b28475edc2f586d44 216 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 135 150 - T 13-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 Astex_1269 8b4fb16b3eec094b28475edc2f586d44 216 SUPERFAMILY SSF53335 18 212 2.09E-37 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Astex_1269 8b4fb16b3eec094b28475edc2f586d44 216 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 6 214 35.012 T 13-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 Astex_1269 8b4fb16b3eec094b28475edc2f586d44 216 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 11 213 8.7E-59 T 13-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 Astex_1269 8b4fb16b3eec094b28475edc2f586d44 216 Gene3D G3DSA:3.40.50.150 2 215 3.7E-66 T 13-10-2018 Astex_1731 251f70f53e5cda69fd46ad8279595db3 332 PIRSF PIRSF000116 7 330 8.0E-42 T 13-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 Astex_1731 251f70f53e5cda69fd46ad8279595db3 332 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 187 323 4.6E-45 T 13-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 Astex_1731 251f70f53e5cda69fd46ad8279595db3 332 SUPERFAMILY SSF51735 4 185 8.09E-56 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_1731 251f70f53e5cda69fd46ad8279595db3 332 SUPERFAMILY SSF48179 187 319 1.7E-45 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Astex_1731 251f70f53e5cda69fd46ad8279595db3 332 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 17 314 1.0E-100 T 13-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 Astex_1731 251f70f53e5cda69fd46ad8279595db3 332 Gene3D G3DSA:3.40.50.720 1 184 1.5E-63 T 13-10-2018 Astex_1731 251f70f53e5cda69fd46ad8279595db3 332 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 16 180 4.3E-55 T 13-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 Astex_1731 251f70f53e5cda69fd46ad8279595db3 332 Gene3D G3DSA:1.10.3730.40 185 329 1.7E-48 T 13-10-2018 Astex_2461 1fb12719df502befdb014cbf28b31f44 91 Gene3D G3DSA:4.10.520.10 1 91 3.1E-30 T 13-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 Astex_2461 1fb12719df502befdb014cbf28b31f44 91 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 6.3E-13 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Astex_2461 1fb12719df502befdb014cbf28b31f44 91 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 6.3E-13 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Astex_2461 1fb12719df502befdb014cbf28b31f44 91 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 6.3E-13 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Astex_2461 1fb12719df502befdb014cbf28b31f44 91 SUPERFAMILY SSF47729 1 90 3.24E-28 T 13-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 Astex_2461 1fb12719df502befdb014cbf28b31f44 91 SMART SM00411 1 90 3.3E-39 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Astex_2461 1fb12719df502befdb014cbf28b31f44 91 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 13-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 Astex_2461 1fb12719df502befdb014cbf28b31f44 91 Pfam PF00216 Bacterial DNA-binding protein 1 90 4.5E-29 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Astex_3816 129b08f9c4d48a4b89f7c0bd3fef5000 220 Gene3D G3DSA:3.40.50.1390 1 125 2.7E-28 T 13-10-2018 Astex_3816 129b08f9c4d48a4b89f7c0bd3fef5000 220 Pfam PF13936 Helix-turn-helix domain 142 178 1.1E-6 T 13-10-2018 IPR025246 Transposase IS30-like HTH domain Astex_3816 129b08f9c4d48a4b89f7c0bd3fef5000 220 SMART SM00857 2 137 3.1E-27 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 Astex_3816 129b08f9c4d48a4b89f7c0bd3fef5000 220 SUPERFAMILY SSF53041 1 135 3.79E-27 T 13-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 Astex_3816 129b08f9c4d48a4b89f7c0bd3fef5000 220 Pfam PF00239 Resolvase, N terminal domain 3 135 4.6E-26 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 Astex_0205 836530b1fc5c923df497be27a3526169 320 Hamap MF_00487 Malate dehydrogenase [mdh]. 3 313 45.021 T 13-10-2018 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 Astex_0205 836530b1fc5c923df497be27a3526169 320 SUPERFAMILY SSF56327 144 312 1.73E-53 T 13-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 Astex_0205 836530b1fc5c923df497be27a3526169 320 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 147 311 5.7E-28 T 13-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 Astex_0205 836530b1fc5c923df497be27a3526169 320 TIGRFAM TIGR01763 MalateDH_bact: malate dehydrogenase, NAD-dependent 3 309 1.1E-120 T 13-10-2018 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 Astex_0205 836530b1fc5c923df497be27a3526169 320 SUPERFAMILY SSF51735 5 144 3.82E-47 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_0205 836530b1fc5c923df497be27a3526169 320 Gene3D G3DSA:3.90.110.10 146 320 1.5E-61 T 13-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 Astex_0205 836530b1fc5c923df497be27a3526169 320 PIRSF PIRSF000102 1 316 4.0E-103 T 13-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 Astex_0205 836530b1fc5c923df497be27a3526169 320 PRINTS PR00086 L-lactate dehydrogenase signature 29 53 9.5E-29 T 13-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 Astex_0205 836530b1fc5c923df497be27a3526169 320 PRINTS PR00086 L-lactate dehydrogenase signature 5 29 9.5E-29 T 13-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 Astex_0205 836530b1fc5c923df497be27a3526169 320 PRINTS PR00086 L-lactate dehydrogenase signature 141 159 9.5E-29 T 13-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 Astex_0205 836530b1fc5c923df497be27a3526169 320 PRINTS PR00086 L-lactate dehydrogenase signature 171 184 9.5E-29 T 13-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 Astex_0205 836530b1fc5c923df497be27a3526169 320 PRINTS PR00086 L-lactate dehydrogenase signature 117 137 9.5E-29 T 13-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 Astex_0205 836530b1fc5c923df497be27a3526169 320 Gene3D G3DSA:3.40.50.720 1 145 2.8E-55 T 13-10-2018 Astex_0205 836530b1fc5c923df497be27a3526169 320 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 5 143 1.4E-39 T 13-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 Astex_1152 86dd017d5a27cccd2f1bc75aa1295103 311 Pfam PF14572 Phosphoribosyl synthetase-associated domain 200 310 7.1E-27 T 13-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 Astex_1152 86dd017d5a27cccd2f1bc75aa1295103 311 Gene3D G3DSA:3.40.50.2020 5 299 5.2E-121 T 13-10-2018 Astex_1152 86dd017d5a27cccd2f1bc75aa1295103 311 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 1 311 6.7E-116 T 13-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 Astex_1152 86dd017d5a27cccd2f1bc75aa1295103 311 Hamap MF_00583_B Putative ribose-phosphate pyrophosphokinase [prs]. 1 311 48.738 T 13-10-2018 IPR037515 Ribose-phosphate pyrophosphokinase, bacterial-type GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 Astex_1152 86dd017d5a27cccd2f1bc75aa1295103 311 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 1 117 6.7E-47 T 13-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 Astex_1152 86dd017d5a27cccd2f1bc75aa1295103 311 Gene3D G3DSA:3.40.50.2020 144 287 5.2E-121 T 13-10-2018 Astex_1152 86dd017d5a27cccd2f1bc75aa1295103 311 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 125 140 - T 13-10-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 Astex_1152 86dd017d5a27cccd2f1bc75aa1295103 311 SMART SM01400 1 117 1.4E-74 T 13-10-2018 Astex_1152 86dd017d5a27cccd2f1bc75aa1295103 311 SUPERFAMILY SSF53271 66 303 8.68E-62 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like Astex_2213 e8a9a5d401aa8ede43ce64b0950bfaa4 449 Gene3D G3DSA:3.40.50.720 2 199 1.7E-52 T 13-10-2018 Astex_2213 e8a9a5d401aa8ede43ce64b0950bfaa4 449 SUPERFAMILY SSF51735 9 184 1.1E-33 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_2213 e8a9a5d401aa8ede43ce64b0950bfaa4 449 PIRSF PIRSF500136 2 428 1.7E-91 T 13-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 Astex_2213 e8a9a5d401aa8ede43ce64b0950bfaa4 449 SUPERFAMILY SSF52413 311 420 1.22E-13 T 13-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 Astex_2213 e8a9a5d401aa8ede43ce64b0950bfaa4 449 Gene3D G3DSA:3.40.50.720 202 445 2.1E-42 T 13-10-2018 Astex_2213 e8a9a5d401aa8ede43ce64b0950bfaa4 449 SUPERFAMILY SSF48179 203 293 7.48E-17 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Astex_2213 e8a9a5d401aa8ede43ce64b0950bfaa4 449 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 10 183 1.3E-37 T 13-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 Astex_2213 e8a9a5d401aa8ede43ce64b0950bfaa4 449 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 203 292 8.0E-18 T 13-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 Astex_2213 e8a9a5d401aa8ede43ce64b0950bfaa4 449 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 319 419 5.8E-13 T 13-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 Astex_2213 e8a9a5d401aa8ede43ce64b0950bfaa4 449 PIRSF PIRSF000124 9 432 2.7E-62 T 13-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 Astex_2213 e8a9a5d401aa8ede43ce64b0950bfaa4 449 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 9 412 1.1E-95 T 13-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 Astex_2213 e8a9a5d401aa8ede43ce64b0950bfaa4 449 SMART SM00984 319 424 2.2E-15 T 13-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 Astex_1423 8df28198b096bdd5190395ac6fa20c73 268 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 189 209 1.5E-64 T 13-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 Astex_1423 8df28198b096bdd5190395ac6fa20c73 268 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 101 120 1.5E-64 T 13-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 Astex_1423 8df28198b096bdd5190395ac6fa20c73 268 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 234 259 1.5E-64 T 13-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 Astex_1423 8df28198b096bdd5190395ac6fa20c73 268 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 62 81 1.5E-64 T 13-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 Astex_1423 8df28198b096bdd5190395ac6fa20c73 268 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 81 101 1.5E-64 T 13-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 Astex_1423 8df28198b096bdd5190395ac6fa20c73 268 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 210 231 1.5E-64 T 13-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 Astex_1423 8df28198b096bdd5190395ac6fa20c73 268 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 120 132 1.2E-22 T 13-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 Astex_1423 8df28198b096bdd5190395ac6fa20c73 268 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 160 172 1.2E-22 T 13-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 Astex_1423 8df28198b096bdd5190395ac6fa20c73 268 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 182 194 1.2E-22 T 13-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 Astex_1423 8df28198b096bdd5190395ac6fa20c73 268 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 132 146 1.2E-22 T 13-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 Astex_1423 8df28198b096bdd5190395ac6fa20c73 268 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 60 69 1.2E-22 T 13-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 Astex_1423 8df28198b096bdd5190395ac6fa20c73 268 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 250 260 1.2E-22 T 13-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 Astex_1423 8df28198b096bdd5190395ac6fa20c73 268 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 237 249 - T 13-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 Astex_1423 8df28198b096bdd5190395ac6fa20c73 268 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 64 260 5.8E-86 T 13-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 Astex_1423 8df28198b096bdd5190395ac6fa20c73 268 Pfam PF00813 FliP family 64 256 4.6E-77 T 13-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 Astex_0450 12b77bc7e5e13a991a3e366a2b2db049 470 Hamap MF_00675 Uronate isomerase [uxaC]. 4 470 39.721 T 13-10-2018 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 Astex_0450 12b77bc7e5e13a991a3e366a2b2db049 470 Gene3D G3DSA:1.10.2020.10 57 147 2.1E-34 T 13-10-2018 Astex_0450 12b77bc7e5e13a991a3e366a2b2db049 470 Pfam PF02614 Glucuronate isomerase 20 465 9.7E-75 T 13-10-2018 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 Astex_0450 12b77bc7e5e13a991a3e366a2b2db049 470 Gene3D G3DSA:3.20.20.140 5 56 1.3E-15 T 13-10-2018 Astex_0450 12b77bc7e5e13a991a3e366a2b2db049 470 SUPERFAMILY SSF51556 6 469 1.33E-154 T 13-10-2018 IPR032466 Metal-dependent hydrolase Astex_0450 12b77bc7e5e13a991a3e366a2b2db049 470 Gene3D G3DSA:3.20.20.140 148 470 1.6E-92 T 13-10-2018 Astex_3607 75fd40e388d98b5a7cccf656faa8e5e9 519 Pfam PF13229 Right handed beta helix region 177 338 7.5E-10 T 13-10-2018 IPR039448 Right handed beta helix domain Astex_3607 75fd40e388d98b5a7cccf656faa8e5e9 519 SMART SM00710 257 279 2900.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat Astex_3607 75fd40e388d98b5a7cccf656faa8e5e9 519 SMART SM00710 203 224 170.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat Astex_3607 75fd40e388d98b5a7cccf656faa8e5e9 519 SMART SM00710 225 247 14.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat Astex_3607 75fd40e388d98b5a7cccf656faa8e5e9 519 SMART SM00710 331 353 2200.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat Astex_3607 75fd40e388d98b5a7cccf656faa8e5e9 519 SMART SM00710 305 325 1300.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat Astex_3607 75fd40e388d98b5a7cccf656faa8e5e9 519 Gene3D G3DSA:2.160.20.10 21 425 9.3E-88 T 13-10-2018 IPR012334 Pectin lyase fold Astex_3607 75fd40e388d98b5a7cccf656faa8e5e9 519 Pfam PF12708 Pectate lyase superfamily protein 29 86 4.3E-10 T 13-10-2018 IPR024535 Pectate lyase superfamily protein Astex_3607 75fd40e388d98b5a7cccf656faa8e5e9 519 SUPERFAMILY SSF51126 24 406 2.46E-67 T 13-10-2018 IPR011050 Pectin lyase fold/virulence factor Astex_2720 794282e42d9d9e34e03599fe8f0c52e3 260 Gene3D G3DSA:3.20.20.380 23 257 5.2E-76 T 13-10-2018 IPR036822 Copper homeostasis (CutC) domain superfamily GO:0005507|GO:0055070 Reactome: R-HSA-936837 Astex_2720 794282e42d9d9e34e03599fe8f0c52e3 260 Pfam PF03932 CutC family 24 221 3.4E-63 T 13-10-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 Astex_2720 794282e42d9d9e34e03599fe8f0c52e3 260 SUPERFAMILY SSF110395 24 226 1.96E-58 T 13-10-2018 IPR036822 Copper homeostasis (CutC) domain superfamily GO:0005507|GO:0055070 Reactome: R-HSA-936837 Astex_2720 794282e42d9d9e34e03599fe8f0c52e3 260 Hamap MF_00795 Copper homeostasis protein CutC [cutC]. 23 224 27.762 T 13-10-2018 IPR005627 Copper homeostasis protein CutC GO:0005507|GO:0055070 Reactome: R-HSA-936837 Astex_1373 a83f252878d85dd8b1444268d7072e9b 746 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 375 619 2.6E-52 T 13-10-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 Astex_1373 a83f252878d85dd8b1444268d7072e9b 746 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 95 340 2.2E-43 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_1373 a83f252878d85dd8b1444268d7072e9b 746 SMART SM01217 652 725 9.7E-7 T 13-10-2018 IPR026891 Fibronectin type III-like domain Astex_1373 a83f252878d85dd8b1444268d7072e9b 746 Gene3D G3DSA:2.60.40.10 623 736 1.9E-22 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_1373 a83f252878d85dd8b1444268d7072e9b 746 Gene3D G3DSA:3.20.20.300 16 348 6.9E-90 T 13-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 Astex_1373 a83f252878d85dd8b1444268d7072e9b 746 PRINTS PR00133 Glycosyl hydrolase family 3 signature 167 183 3.8E-27 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_1373 a83f252878d85dd8b1444268d7072e9b 746 PRINTS PR00133 Glycosyl hydrolase family 3 signature 96 112 3.8E-27 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_1373 a83f252878d85dd8b1444268d7072e9b 746 PRINTS PR00133 Glycosyl hydrolase family 3 signature 198 214 3.8E-27 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_1373 a83f252878d85dd8b1444268d7072e9b 746 PRINTS PR00133 Glycosyl hydrolase family 3 signature 121 140 3.8E-27 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_1373 a83f252878d85dd8b1444268d7072e9b 746 PRINTS PR00133 Glycosyl hydrolase family 3 signature 268 286 3.8E-27 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_1373 a83f252878d85dd8b1444268d7072e9b 746 Gene3D G3DSA:3.40.50.1700 361 621 1.5E-68 T 13-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 Astex_1373 a83f252878d85dd8b1444268d7072e9b 746 Pfam PF14310 Fibronectin type III-like domain 653 723 2.6E-10 T 13-10-2018 IPR026891 Fibronectin type III-like domain Astex_1373 a83f252878d85dd8b1444268d7072e9b 746 SUPERFAMILY SSF52279 375 622 3.01E-46 T 13-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 Astex_1373 a83f252878d85dd8b1444268d7072e9b 746 SUPERFAMILY SSF51445 26 372 8.53E-84 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_0405 1ac87bff8c6c85c429e3266a8d3d8d41 328 Gene3D G3DSA:2.130.10.10 244 328 1.5E-6 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 Astex_0405 1ac87bff8c6c85c429e3266a8d3d8d41 328 Gene3D G3DSA:2.130.10.10 5 242 2.9E-18 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 Astex_0405 1ac87bff8c6c85c429e3266a8d3d8d41 328 Pfam PF00400 WD domain, G-beta repeat 41 71 0.23 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 Astex_0405 1ac87bff8c6c85c429e3266a8d3d8d41 328 SMART SM00320 35 75 8.6 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 Astex_0405 1ac87bff8c6c85c429e3266a8d3d8d41 328 SMART SM00320 116 154 1.7 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 Astex_0405 1ac87bff8c6c85c429e3266a8d3d8d41 328 SMART SM00320 244 284 330.0 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 Astex_0405 1ac87bff8c6c85c429e3266a8d3d8d41 328 SMART SM00320 198 236 43.0 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 Astex_0405 1ac87bff8c6c85c429e3266a8d3d8d41 328 SMART SM00320 77 115 140.0 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 Astex_0405 1ac87bff8c6c85c429e3266a8d3d8d41 328 SMART SM00320 286 326 8.1 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 Astex_0405 1ac87bff8c6c85c429e3266a8d3d8d41 328 SMART SM00320 161 196 400.0 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 Astex_0405 1ac87bff8c6c85c429e3266a8d3d8d41 328 SUPERFAMILY SSF50978 42 326 1.01E-28 T 13-10-2018 IPR036322 WD40-repeat-containing domain superfamily GO:0005515 Astex_0616 8f47ba239e553b1a4e3dd73c442e622e 822 Pfam PF01627 Hpt domain 28 118 1.7E-15 T 13-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 Astex_0616 8f47ba239e553b1a4e3dd73c442e622e 822 SUPERFAMILY SSF55874 334 516 2.26E-39 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_0616 8f47ba239e553b1a4e3dd73c442e622e 822 SUPERFAMILY SSF47384 271 331 4.32E-13 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Astex_0616 8f47ba239e553b1a4e3dd73c442e622e 822 SMART SM00387 375 518 3.3E-23 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_0616 8f47ba239e553b1a4e3dd73c442e622e 822 Gene3D G3DSA:1.10.287.560 270 330 5.4E-15 T 13-10-2018 IPR037006 Histidine kinase CheA-like, homodimeric domain superfamily GO:0000155|GO:0006935 Astex_0616 8f47ba239e553b1a4e3dd73c442e622e 822 Gene3D G3DSA:1.20.120.160 23 160 2.6E-32 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 Astex_0616 8f47ba239e553b1a4e3dd73c442e622e 822 Gene3D G3DSA:3.30.565.10 331 517 1.3E-55 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_0616 8f47ba239e553b1a4e3dd73c442e622e 822 Pfam PF01584 CheW-like domain 681 799 5.6E-8 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 Astex_0616 8f47ba239e553b1a4e3dd73c442e622e 822 Pfam PF01584 CheW-like domain 523 652 1.7E-22 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 Astex_0616 8f47ba239e553b1a4e3dd73c442e622e 822 SMART SM00073 25 122 1.3E-21 T 13-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 Astex_0616 8f47ba239e553b1a4e3dd73c442e622e 822 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 378 517 3.7E-15 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_0616 8f47ba239e553b1a4e3dd73c442e622e 822 SUPERFAMILY SSF50341 517 650 1.2E-29 T 13-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 Astex_0616 8f47ba239e553b1a4e3dd73c442e622e 822 SUPERFAMILY SSF50341 681 799 2.49E-12 T 13-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 Astex_0616 8f47ba239e553b1a4e3dd73c442e622e 822 PRINTS PR00344 Bacterial sensor protein C-terminal signature 502 515 4.7E-14 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_0616 8f47ba239e553b1a4e3dd73c442e622e 822 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 434 4.7E-14 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_0616 8f47ba239e553b1a4e3dd73c442e622e 822 PRINTS PR00344 Bacterial sensor protein C-terminal signature 462 472 4.7E-14 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_0616 8f47ba239e553b1a4e3dd73c442e622e 822 PRINTS PR00344 Bacterial sensor protein C-terminal signature 478 496 4.7E-14 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_0616 8f47ba239e553b1a4e3dd73c442e622e 822 Gene3D G3DSA:2.30.30.40 518 646 3.0E-38 T 13-10-2018 Astex_0616 8f47ba239e553b1a4e3dd73c442e622e 822 Gene3D G3DSA:2.40.50.180 541 606 3.0E-38 T 13-10-2018 Astex_0616 8f47ba239e553b1a4e3dd73c442e622e 822 SMART SM00260 510 651 4.3E-33 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 Astex_0616 8f47ba239e553b1a4e3dd73c442e622e 822 SMART SM01231 270 330 6.3E-16 T 13-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 Astex_0616 8f47ba239e553b1a4e3dd73c442e622e 822 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 271 330 3.4E-12 T 13-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 Astex_0616 8f47ba239e553b1a4e3dd73c442e622e 822 SUPERFAMILY SSF47226 26 148 6.54E-28 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 Astex_0122 f04a09ac61b52b52336615af4dbeb464 206 SMART SM00474 1 169 9.3E-32 T 13-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 Astex_0122 f04a09ac61b52b52336615af4dbeb464 206 Gene3D G3DSA:3.30.420.10 9 188 1.2E-40 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Astex_0122 f04a09ac61b52b52336615af4dbeb464 206 SUPERFAMILY SSF53098 17 191 2.93E-49 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily Astex_0122 f04a09ac61b52b52336615af4dbeb464 206 Pfam PF01612 3'-5' exonuclease 19 168 3.4E-32 T 13-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 Astex_0816 543d4d6b21b0d5c8943a0e4eded2ce86 500 Gene3D G3DSA:3.40.640.10 21 214 5.9E-36 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Astex_0816 543d4d6b21b0d5c8943a0e4eded2ce86 500 Pfam PF00155 Aminotransferase class I and II 21 252 1.1E-14 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Astex_0816 543d4d6b21b0d5c8943a0e4eded2ce86 500 Gene3D G3DSA:3.30.230.40 399 500 2.1E-34 T 13-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 Astex_0816 543d4d6b21b0d5c8943a0e4eded2ce86 500 SUPERFAMILY SSF54211 311 394 5.82E-29 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Astex_0816 543d4d6b21b0d5c8943a0e4eded2ce86 500 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 463 475 - T 13-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 Astex_0816 543d4d6b21b0d5c8943a0e4eded2ce86 500 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 340 481 2.7E-58 T 13-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 Astex_0816 543d4d6b21b0d5c8943a0e4eded2ce86 500 Gene3D G3DSA:3.90.1150.10 215 300 5.9E-36 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Astex_0816 543d4d6b21b0d5c8943a0e4eded2ce86 500 SUPERFAMILY SSF53383 19 298 5.18E-32 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Astex_0816 543d4d6b21b0d5c8943a0e4eded2ce86 500 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 311 499 34.195 T 13-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 Astex_0816 543d4d6b21b0d5c8943a0e4eded2ce86 500 SUPERFAMILY SSF54211 397 485 2.28E-27 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Astex_0816 543d4d6b21b0d5c8943a0e4eded2ce86 500 Gene3D G3DSA:3.30.230.40 301 398 5.4E-34 T 13-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 Astex_3339 3336814334f8e73e2365413858c7e99e 696 Pfam PF07488 Glycosyl hydrolase family 67 middle domain 138 448 1.0E-142 T 13-10-2018 IPR011100 Glycosyl hydrolase family 67, catalytic domain GO:0005576|GO:0045493|GO:0046559 Astex_3339 3336814334f8e73e2365413858c7e99e 696 Pfam PF03648 Glycosyl hydrolase family 67 N-terminus 27 130 2.2E-16 T 13-10-2018 IPR005154 Alpha glucuronidase, N-terminal GO:0045493|GO:0046559 Astex_3339 3336814334f8e73e2365413858c7e99e 696 PIRSF PIRSF029900 4 696 1.1E-276 T 13-10-2018 IPR011395 Alpha glucuronidase GO:0005576|GO:0045493|GO:0046559 Astex_3339 3336814334f8e73e2365413858c7e99e 696 Gene3D G3DSA:3.90.1330.10 471 694 4.9E-87 T 13-10-2018 IPR037054 Alpha-glucuronidase, C-terminal domain superfamily GO:0005576|GO:0045493|GO:0046559 Astex_3339 3336814334f8e73e2365413858c7e99e 696 Gene3D G3DSA:3.20.20.80 147 469 3.5E-151 T 13-10-2018 Astex_3339 3336814334f8e73e2365413858c7e99e 696 Pfam PF07477 Glycosyl hydrolase family 67 C-terminus 450 673 1.1E-89 T 13-10-2018 IPR011099 Glycosyl hydrolase family 67, C-terminal GO:0005576|GO:0045493|GO:0046559 Astex_3339 3336814334f8e73e2365413858c7e99e 696 Gene3D G3DSA:3.30.379.10 34 144 6.2E-22 T 13-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 Astex_3339 3336814334f8e73e2365413858c7e99e 696 SUPERFAMILY SSF55545 22 145 4.01E-28 T 13-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 Astex_3339 3336814334f8e73e2365413858c7e99e 696 SUPERFAMILY SSF51445 149 693 6.74E-231 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_1307 e8c7bcb8ce00e049126dd8534d0888e3 968 SUPERFAMILY SSF56935 54 968 2.38E-78 T 13-10-2018 Astex_1307 e8c7bcb8ce00e049126dd8534d0888e3 968 Pfam PF07715 TonB-dependent Receptor Plug Domain 68 187 9.8E-20 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_1307 e8c7bcb8ce00e049126dd8534d0888e3 968 Pfam PF00593 TonB dependent receptor 422 965 2.1E-18 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_1307 e8c7bcb8ce00e049126dd8534d0888e3 968 Gene3D G3DSA:2.170.130.10 48 190 1.1E-34 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_3676 e6af84402ea5549604aeed3f57dd77db 239 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 234 8.4E-56 T 13-10-2018 Astex_3676 e6af84402ea5549604aeed3f57dd77db 239 SUPERFAMILY SSF51735 5 236 2.47E-69 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_3676 e6af84402ea5549604aeed3f57dd77db 239 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Astex_3676 e6af84402ea5549604aeed3f57dd77db 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 8.8E-28 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_3676 e6af84402ea5549604aeed3f57dd77db 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 8.8E-28 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_3676 e6af84402ea5549604aeed3f57dd77db 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 8.8E-28 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_3676 e6af84402ea5549604aeed3f57dd77db 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 219 8.8E-28 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_3676 e6af84402ea5549604aeed3f57dd77db 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 8.8E-28 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_3676 e6af84402ea5549604aeed3f57dd77db 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 8.8E-28 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_3676 e6af84402ea5549604aeed3f57dd77db 239 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 180 3.4E-4 T 13-10-2018 Astex_3676 e6af84402ea5549604aeed3f57dd77db 239 Gene3D G3DSA:3.40.50.720 1 238 3.8E-70 T 13-10-2018 Astex_1627 94e4505de86cf9f6bb95f7fca3feb2ca 566 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 33 557 3.1E-115 T 13-10-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-4061|MetaCyc: PWY-5826|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7559 Astex_1627 94e4505de86cf9f6bb95f7fca3feb2ca 566 SUPERFAMILY SSF56235 31 563 1.04E-143 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Astex_1627 94e4505de86cf9f6bb95f7fca3feb2ca 566 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 129 147 2.0E-53 T 13-10-2018 Astex_1627 94e4505de86cf9f6bb95f7fca3feb2ca 566 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 147 166 2.0E-53 T 13-10-2018 Astex_1627 94e4505de86cf9f6bb95f7fca3feb2ca 566 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 443 458 2.0E-53 T 13-10-2018 Astex_1627 94e4505de86cf9f6bb95f7fca3feb2ca 566 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 406 424 2.0E-53 T 13-10-2018 Astex_1627 94e4505de86cf9f6bb95f7fca3feb2ca 566 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 277 296 2.0E-53 T 13-10-2018 Astex_1627 94e4505de86cf9f6bb95f7fca3feb2ca 566 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 384 402 2.0E-53 T 13-10-2018 Astex_1627 94e4505de86cf9f6bb95f7fca3feb2ca 566 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 54 79 2.0E-53 T 13-10-2018 Astex_1627 94e4505de86cf9f6bb95f7fca3feb2ca 566 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 468 485 2.0E-53 T 13-10-2018 Astex_1627 94e4505de86cf9f6bb95f7fca3feb2ca 566 Gene3D G3DSA:3.60.20.40 380 563 8.3E-52 T 13-10-2018 Astex_1627 94e4505de86cf9f6bb95f7fca3feb2ca 566 Pfam PF01019 Gamma-glutamyltranspeptidase 47 560 3.6E-142 T 13-10-2018 Astex_1627 94e4505de86cf9f6bb95f7fca3feb2ca 566 Gene3D G3DSA:1.10.246.130 264 379 5.5E-34 T 13-10-2018 Astex_3841 e05220412fa753a71f1fd99ed16d4870 498 Pfam PF11604 Copper binding periplasmic protein CusF 429 492 2.1E-20 T 13-10-2018 IPR021647 Copper binding periplasmic protein CusF Astex_3841 e05220412fa753a71f1fd99ed16d4870 498 Gene3D G3DSA:2.40.30.170 232 327 1.6E-28 T 13-10-2018 Astex_3841 e05220412fa753a71f1fd99ed16d4870 498 Gene3D G3DSA:2.40.420.20 328 409 7.1E-24 T 13-10-2018 Astex_3841 e05220412fa753a71f1fd99ed16d4870 498 Gene3D G3DSA:2.40.50.100 130 177 1.0E-5 T 13-10-2018 Astex_3841 e05220412fa753a71f1fd99ed16d4870 498 SUPERFAMILY SSF111369 131 326 3.01E-11 T 13-10-2018 Astex_3841 e05220412fa753a71f1fd99ed16d4870 498 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 218 395 2.3E-38 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 Astex_3841 e05220412fa753a71f1fd99ed16d4870 498 Gene3D G3DSA:2.40.50.320 423 497 7.2E-23 T 13-10-2018 Astex_3841 e05220412fa753a71f1fd99ed16d4870 498 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 115 322 1.9E-67 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain Astex_3125 aed30278039e48b6e92eafc6bb53412a 593 SMART SM00028 267 300 98.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Astex_3125 aed30278039e48b6e92eafc6bb53412a 593 SMART SM00028 342 375 110.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Astex_3125 aed30278039e48b6e92eafc6bb53412a 593 SMART SM00028 516 549 150.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Astex_3125 aed30278039e48b6e92eafc6bb53412a 593 SMART SM00028 482 515 0.2 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Astex_3125 aed30278039e48b6e92eafc6bb53412a 593 SMART SM00028 413 446 0.011 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Astex_3125 aed30278039e48b6e92eafc6bb53412a 593 Gene3D G3DSA:1.25.40.10 79 252 7.4E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_3125 aed30278039e48b6e92eafc6bb53412a 593 SUPERFAMILY SSF48452 34 330 3.1E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_3125 aed30278039e48b6e92eafc6bb53412a 593 Pfam PF13429 Tetratricopeptide repeat 415 536 4.7E-10 T 13-10-2018 Astex_3125 aed30278039e48b6e92eafc6bb53412a 593 Gene3D G3DSA:1.25.40.10 253 561 7.8E-39 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_3125 aed30278039e48b6e92eafc6bb53412a 593 SUPERFAMILY SSF48452 309 548 7.02E-24 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_3125 aed30278039e48b6e92eafc6bb53412a 593 Pfam PF13432 Tetratricopeptide repeat 314 375 0.0024 T 13-10-2018 Astex_3022 4bcbaf0e8796823ae02d907a12392f74 382 SMART SM00474 1 169 1.7E-38 T 13-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 Astex_3022 4bcbaf0e8796823ae02d907a12392f74 382 SUPERFAMILY SSF53098 3 202 4.38E-66 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily Astex_3022 4bcbaf0e8796823ae02d907a12392f74 382 SUPERFAMILY SSF47819 304 367 3.55E-12 T 13-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 Astex_3022 4bcbaf0e8796823ae02d907a12392f74 382 SUPERFAMILY SSF47819 189 296 1.25E-18 T 13-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 Astex_3022 4bcbaf0e8796823ae02d907a12392f74 382 SMART SM00341 208 288 6.7E-4 T 13-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 Astex_3022 4bcbaf0e8796823ae02d907a12392f74 382 Gene3D G3DSA:3.30.420.10 1 189 5.9E-62 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Astex_3022 4bcbaf0e8796823ae02d907a12392f74 382 Pfam PF01612 3'-5' exonuclease 3 168 6.6E-37 T 13-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 Astex_3022 4bcbaf0e8796823ae02d907a12392f74 382 Gene3D G3DSA:1.10.150.80 193 291 9.1E-16 T 13-10-2018 Astex_3022 4bcbaf0e8796823ae02d907a12392f74 382 TIGRFAM TIGR01388 rnd: ribonuclease D 4 365 8.0E-130 T 13-10-2018 IPR006292 Ribonuclease D GO:0008033|GO:0008408|GO:0033890 Astex_3022 4bcbaf0e8796823ae02d907a12392f74 382 Pfam PF00570 HRDC domain 212 274 2.3E-11 T 13-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 Astex_3022 4bcbaf0e8796823ae02d907a12392f74 382 Hamap MF_01899 Ribonuclease D [rnd]. 1 364 43.7 T 13-10-2018 IPR006292 Ribonuclease D GO:0008033|GO:0008408|GO:0033890 Astex_1274 37566660d4685a7e63a294aaa02b2a7a 150 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 51 1.4E-14 T 13-10-2018 Astex_1274 37566660d4685a7e63a294aaa02b2a7a 150 SUPERFAMILY SSF46785 4 61 1.32E-14 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_1274 37566660d4685a7e63a294aaa02b2a7a 150 Gene3D G3DSA:1.10.10.10 1 57 3.4E-22 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1274 37566660d4685a7e63a294aaa02b2a7a 150 Pfam PF01037 Lrp/AsnC ligand binding domain 70 143 3.3E-21 T 13-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Astex_1274 37566660d4685a7e63a294aaa02b2a7a 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 1.2E-14 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 Astex_1274 37566660d4685a7e63a294aaa02b2a7a 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 1.2E-14 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 Astex_1274 37566660d4685a7e63a294aaa02b2a7a 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 1.2E-14 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 Astex_1274 37566660d4685a7e63a294aaa02b2a7a 150 Gene3D G3DSA:3.30.70.920 60 141 2.2E-22 T 13-10-2018 Astex_1274 37566660d4685a7e63a294aaa02b2a7a 150 SUPERFAMILY SSF54909 66 146 1.47E-17 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel Astex_1274 37566660d4685a7e63a294aaa02b2a7a 150 SMART SM00344 4 113 8.5E-37 T 13-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 Astex_1739 1ab23fd3c1bd5754d81a0bfca502321b 284 Pfam PF01715 IPP transferase 39 282 3.0E-56 T 13-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 Astex_1739 1ab23fd3c1bd5754d81a0bfca502321b 284 Gene3D G3DSA:3.40.50.300 11 281 8.7E-74 T 13-10-2018 Astex_1739 1ab23fd3c1bd5754d81a0bfca502321b 284 SUPERFAMILY SSF52540 6 146 8.71E-16 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1739 1ab23fd3c1bd5754d81a0bfca502321b 284 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 7 282 3.3E-63 T 13-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 Astex_1739 1ab23fd3c1bd5754d81a0bfca502321b 284 Gene3D G3DSA:1.10.20.140 113 184 8.7E-74 T 13-10-2018 Astex_1739 1ab23fd3c1bd5754d81a0bfca502321b 284 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 6 284 21.495 T 13-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 Astex_3031 a697b2d292a82907712499deb808ce7f 423 SUPERFAMILY SSF54534 183 286 7.85E-20 T 13-10-2018 Astex_3031 a697b2d292a82907712499deb808ce7f 423 Pfam PF13624 SurA N-terminal domain 39 155 2.4E-15 T 13-10-2018 Astex_3031 a697b2d292a82907712499deb808ce7f 423 Gene3D G3DSA:3.10.50.40 185 285 2.3E-55 T 13-10-2018 Astex_3031 a697b2d292a82907712499deb808ce7f 423 SUPERFAMILY SSF109998 42 210 6.54E-33 T 13-10-2018 IPR027304 Trigger factor/SurA domain superfamily Astex_3031 a697b2d292a82907712499deb808ce7f 423 Gene3D G3DSA:1.10.4030.30 42 298 2.3E-55 T 13-10-2018 Astex_3031 a697b2d292a82907712499deb808ce7f 423 Pfam PF00639 PPIC-type PPIASE domain 192 282 1.6E-16 T 13-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 Astex_0768 89544a7ba61bb3ed0d34e3babb77d579 156 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 81 96 2.2E-24 T 13-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 Astex_0768 89544a7ba61bb3ed0d34e3babb77d579 156 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 4 21 2.2E-24 T 13-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 Astex_0768 89544a7ba61bb3ed0d34e3babb77d579 156 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 47 63 2.2E-24 T 13-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 Astex_0768 89544a7ba61bb3ed0d34e3babb77d579 156 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 122 137 2.2E-24 T 13-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 Astex_0768 89544a7ba61bb3ed0d34e3babb77d579 156 SUPERFAMILY SSF52788 1 151 7.72E-50 T 13-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily Astex_0768 89544a7ba61bb3ed0d34e3babb77d579 156 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 148 4.8E-40 T 13-10-2018 IPR023485 Phosphotyrosine protein phosphatase I Astex_0768 89544a7ba61bb3ed0d34e3babb77d579 156 SMART SM00226 2 150 3.2E-55 T 13-10-2018 IPR023485 Phosphotyrosine protein phosphatase I Astex_0768 89544a7ba61bb3ed0d34e3babb77d579 156 Gene3D G3DSA:3.40.50.2300 1 155 2.9E-55 T 13-10-2018 Astex_2259 efdc8169b89230de7b7b6e4072486922 299 SUPERFAMILY SSF51735 1 290 2.54E-90 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_2259 efdc8169b89230de7b7b6e4072486922 299 Gene3D G3DSA:3.40.50.720 3 277 7.6E-98 T 13-10-2018 Astex_2259 efdc8169b89230de7b7b6e4072486922 299 Pfam PF04321 RmlD substrate binding domain 1 290 2.3E-103 T 13-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 Astex_2259 efdc8169b89230de7b7b6e4072486922 299 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 288 1.2E-90 T 13-10-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 Astex_2259 efdc8169b89230de7b7b6e4072486922 299 Gene3D G3DSA:3.90.25.10 159 284 7.6E-98 T 13-10-2018 Astex_2923 3fb0c4f419a1590739ca6a5157495764 425 SUPERFAMILY SSF54826 3 137 2.36E-58 T 13-10-2018 Astex_2923 3fb0c4f419a1590739ca6a5157495764 425 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 423 2.1E-127 T 13-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Astex_2923 3fb0c4f419a1590739ca6a5157495764 425 PIRSF PIRSF001400 1 424 1.9E-186 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Astex_2923 3fb0c4f419a1590739ca6a5157495764 425 Gene3D G3DSA:3.20.20.120 129 425 3.8E-128 T 13-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily Astex_2923 3fb0c4f419a1590739ca6a5157495764 425 SMART SM01192 139 425 1.8E-212 T 13-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Astex_2923 3fb0c4f419a1590739ca6a5157495764 425 PRINTS PR00148 Enolase signature 107 123 6.5E-47 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Astex_2923 3fb0c4f419a1590739ca6a5157495764 425 PRINTS PR00148 Enolase signature 311 322 6.5E-47 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Astex_2923 3fb0c4f419a1590739ca6a5157495764 425 PRINTS PR00148 Enolase signature 334 348 6.5E-47 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Astex_2923 3fb0c4f419a1590739ca6a5157495764 425 PRINTS PR00148 Enolase signature 37 51 6.5E-47 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Astex_2923 3fb0c4f419a1590739ca6a5157495764 425 PRINTS PR00148 Enolase signature 363 380 6.5E-47 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Astex_2923 3fb0c4f419a1590739ca6a5157495764 425 PRINTS PR00148 Enolase signature 161 174 6.5E-47 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Astex_2923 3fb0c4f419a1590739ca6a5157495764 425 Gene3D G3DSA:3.30.390.10 1 126 8.0E-57 T 13-10-2018 IPR029017 Enolase-like, N-terminal Astex_2923 3fb0c4f419a1590739ca6a5157495764 425 ProSitePatterns PS00164 Enolase signature. 334 347 - T 13-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_2923 3fb0c4f419a1590739ca6a5157495764 425 Hamap MF_00318 Enolase [eno]. 2 411 44.464 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Astex_2923 3fb0c4f419a1590739ca6a5157495764 425 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 422 1.6E-202 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Astex_2923 3fb0c4f419a1590739ca6a5157495764 425 Pfam PF03952 Enolase, N-terminal domain 4 134 9.6E-61 T 13-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Astex_2923 3fb0c4f419a1590739ca6a5157495764 425 SUPERFAMILY SSF51604 139 422 2.97E-123 T 13-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily Astex_2923 3fb0c4f419a1590739ca6a5157495764 425 SMART SM01193 4 134 3.4E-95 T 13-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 Astex_0035 78f149384dfdafdd2313e0c8206ffe97 901 Pfam PF05192 MutS domain III 288 593 6.2E-35 T 13-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 Astex_0035 78f149384dfdafdd2313e0c8206ffe97 901 Gene3D G3DSA:1.10.1420.10 285 593 8.4E-74 T 13-10-2018 Astex_0035 78f149384dfdafdd2313e0c8206ffe97 901 SMART SM00533 302 625 3.3E-66 T 13-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 Astex_0035 78f149384dfdafdd2313e0c8206ffe97 901 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 19 898 1.0E-233 T 13-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 Astex_0035 78f149384dfdafdd2313e0c8206ffe97 901 Pfam PF05190 MutS family domain IV 459 550 6.8E-17 T 13-10-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 Astex_0035 78f149384dfdafdd2313e0c8206ffe97 901 Pfam PF05188 MutS domain II 144 267 7.1E-15 T 13-10-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 Astex_0035 78f149384dfdafdd2313e0c8206ffe97 901 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 18 893 22.113 T 13-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 Astex_0035 78f149384dfdafdd2313e0c8206ffe97 901 Gene3D G3DSA:3.30.420.110 143 277 2.2E-17 T 13-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 Astex_0035 78f149384dfdafdd2313e0c8206ffe97 901 SUPERFAMILY SSF48334 286 598 2.62E-65 T 13-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily Astex_0035 78f149384dfdafdd2313e0c8206ffe97 901 Pfam PF00488 MutS domain V 652 838 4.0E-78 T 13-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 Astex_0035 78f149384dfdafdd2313e0c8206ffe97 901 Pfam PF01624 MutS domain I 19 135 2.1E-38 T 13-10-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 Astex_0035 78f149384dfdafdd2313e0c8206ffe97 901 SUPERFAMILY SSF55271 15 131 1.19E-37 T 13-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 Astex_0035 78f149384dfdafdd2313e0c8206ffe97 901 Gene3D G3DSA:3.40.1170.10 10 137 1.7E-45 T 13-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 Astex_0035 78f149384dfdafdd2313e0c8206ffe97 901 SUPERFAMILY SSF52540 602 839 4.9E-54 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0035 78f149384dfdafdd2313e0c8206ffe97 901 SMART SM00534 648 835 1.9E-99 T 13-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 Astex_0035 78f149384dfdafdd2313e0c8206ffe97 901 SUPERFAMILY SSF53150 130 284 5.49E-27 T 13-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 Astex_0035 78f149384dfdafdd2313e0c8206ffe97 901 Gene3D G3DSA:3.40.50.300 603 893 4.3E-88 T 13-10-2018 Astex_0035 78f149384dfdafdd2313e0c8206ffe97 901 Gene3D G3DSA:1.10.1420.10 406 537 8.4E-74 T 13-10-2018 Astex_0035 78f149384dfdafdd2313e0c8206ffe97 901 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 729 745 - T 13-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 Astex_0035 78f149384dfdafdd2313e0c8206ffe97 901 PIRSF PIRSF037677 247 881 3.4E-98 T 13-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 Astex_0035 78f149384dfdafdd2313e0c8206ffe97 901 PIRSF PIRSF037677 7 220 8.3E-31 T 13-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 Astex_1570 2dcbe11f1b09bd7414ea6035cc785100 703 Pfam PF14905 Outer membrane protein beta-barrel family 308 699 3.4E-34 T 13-10-2018 Astex_1570 2dcbe11f1b09bd7414ea6035cc785100 703 SUPERFAMILY SSF56935 51 701 4.76E-67 T 13-10-2018 Astex_1570 2dcbe11f1b09bd7414ea6035cc785100 703 Pfam PF07715 TonB-dependent Receptor Plug Domain 80 153 3.5E-6 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_1570 2dcbe11f1b09bd7414ea6035cc785100 703 Gene3D G3DSA:2.40.170.20 196 701 3.7E-28 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_1570 2dcbe11f1b09bd7414ea6035cc785100 703 Gene3D G3DSA:2.170.130.10 70 166 5.2E-11 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_1153 14d1f11c1cb32cf327bc85bb42656d2d 119 PIRSF PIRSF030561 1 113 1.5E-30 T 13-10-2018 IPR008317 Uncharacterised conserved protein UCP030561 Astex_1153 14d1f11c1cb32cf327bc85bb42656d2d 119 Gene3D G3DSA:3.10.450.50 1 118 3.9E-36 T 13-10-2018 Astex_1153 14d1f11c1cb32cf327bc85bb42656d2d 119 Pfam PF12680 SnoaL-like domain 12 108 4.4E-9 T 13-10-2018 IPR037401 SnoaL-like domain Astex_1153 14d1f11c1cb32cf327bc85bb42656d2d 119 SUPERFAMILY SSF54427 1 116 1.28E-25 T 13-10-2018 IPR032710 NTF2-like domain superfamily Astex_1947 d0e453f5b57136f032b8cce91c7a2e86 863 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 86 408 8.0E-81 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_1947 d0e453f5b57136f032b8cce91c7a2e86 863 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 450 665 5.7E-31 T 13-10-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 Astex_1947 d0e453f5b57136f032b8cce91c7a2e86 863 SUPERFAMILY SSF52279 450 666 6.54E-47 T 13-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 Astex_1947 d0e453f5b57136f032b8cce91c7a2e86 863 Gene3D G3DSA:3.40.50.1700 435 668 4.5E-67 T 13-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 Astex_1947 d0e453f5b57136f032b8cce91c7a2e86 863 PRINTS PR00133 Glycosyl hydrolase family 3 signature 262 278 2.8E-19 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_1947 d0e453f5b57136f032b8cce91c7a2e86 863 PRINTS PR00133 Glycosyl hydrolase family 3 signature 175 194 2.8E-19 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_1947 d0e453f5b57136f032b8cce91c7a2e86 863 PRINTS PR00133 Glycosyl hydrolase family 3 signature 221 237 2.8E-19 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_1947 d0e453f5b57136f032b8cce91c7a2e86 863 PRINTS PR00133 Glycosyl hydrolase family 3 signature 151 167 2.8E-19 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_1947 d0e453f5b57136f032b8cce91c7a2e86 863 PRINTS PR00133 Glycosyl hydrolase family 3 signature 332 350 2.8E-19 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_1947 d0e453f5b57136f032b8cce91c7a2e86 863 Gene3D G3DSA:3.20.20.300 71 429 1.6E-125 T 13-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 Astex_1947 d0e453f5b57136f032b8cce91c7a2e86 863 Gene3D G3DSA:2.60.120.430 695 863 1.3E-7 T 13-10-2018 Astex_1947 d0e453f5b57136f032b8cce91c7a2e86 863 SUPERFAMILY SSF51445 71 449 5.9E-105 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_2715 8a73268c1e65b1cae1a8d5aad496a637 209 Gene3D G3DSA:3.90.226.10 2 204 3.1E-82 T 13-10-2018 Astex_2715 8a73268c1e65b1cae1a8d5aad496a637 209 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 12 202 40.869 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Astex_2715 8a73268c1e65b1cae1a8d5aad496a637 209 PRINTS PR00127 Clp protease catalytic subunit P signature 68 88 2.5E-47 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Astex_2715 8a73268c1e65b1cae1a8d5aad496a637 209 PRINTS PR00127 Clp protease catalytic subunit P signature 99 116 2.5E-47 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Astex_2715 8a73268c1e65b1cae1a8d5aad496a637 209 PRINTS PR00127 Clp protease catalytic subunit P signature 28 43 2.5E-47 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Astex_2715 8a73268c1e65b1cae1a8d5aad496a637 209 PRINTS PR00127 Clp protease catalytic subunit P signature 120 139 2.5E-47 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Astex_2715 8a73268c1e65b1cae1a8d5aad496a637 209 PRINTS PR00127 Clp protease catalytic subunit P signature 177 196 2.5E-47 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Astex_2715 8a73268c1e65b1cae1a8d5aad496a637 209 Pfam PF00574 Clp protease 21 201 4.8E-83 T 13-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA Astex_2715 8a73268c1e65b1cae1a8d5aad496a637 209 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 121 134 - T 13-10-2018 IPR033135 ClpP, histidine active site Astex_2715 8a73268c1e65b1cae1a8d5aad496a637 209 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 99 110 - T 13-10-2018 IPR018215 ClpP, Ser active site Astex_2715 8a73268c1e65b1cae1a8d5aad496a637 209 SUPERFAMILY SSF52096 20 202 3.11E-70 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Astex_1780 e9c385e148a5fa03bec73e174a8b1808 300 SUPERFAMILY SSF56194 195 298 2.75E-34 T 13-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Astex_1780 e9c385e148a5fa03bec73e174a8b1808 300 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 21 298 3.7E-62 T 13-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Astex_1780 e9c385e148a5fa03bec73e174a8b1808 300 Gene3D G3DSA:3.30.465.10 88 214 1.2E-39 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 Astex_1780 e9c385e148a5fa03bec73e174a8b1808 300 Gene3D G3DSA:3.90.78.10 215 300 3.5E-30 T 13-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Astex_1780 e9c385e148a5fa03bec73e174a8b1808 300 Pfam PF01565 FAD binding domain 34 163 2.5E-20 T 13-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 Astex_1780 e9c385e148a5fa03bec73e174a8b1808 300 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 199 296 4.7E-26 T 13-10-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Astex_1780 e9c385e148a5fa03bec73e174a8b1808 300 Gene3D G3DSA:3.30.43.10 5 83 9.8E-21 T 13-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 Astex_1780 e9c385e148a5fa03bec73e174a8b1808 300 SUPERFAMILY SSF56176 12 190 2.4E-44 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 Astex_1780 e9c385e148a5fa03bec73e174a8b1808 300 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 300 95.197 T 13-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Astex_1732 a78e70b842ce6ff469b9e54d489d079c 268 SUPERFAMILY SSF55831 3 268 1.44E-124 T 13-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 Astex_1732 a78e70b842ce6ff469b9e54d489d079c 268 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 8 90 1.4E-40 T 13-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 Astex_1732 a78e70b842ce6ff469b9e54d489d079c 268 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 89 268 1.5E-93 T 13-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 Astex_1732 a78e70b842ce6ff469b9e54d489d079c 268 Gene3D G3DSA:3.30.572.10 7 268 1.5E-127 T 13-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 Astex_1732 a78e70b842ce6ff469b9e54d489d079c 268 Pfam PF00303 Thymidylate synthase 8 268 2.0E-121 T 13-10-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 Astex_1732 a78e70b842ce6ff469b9e54d489d079c 268 PRINTS PR00108 Thymidylate synthase family signature 120 139 5.7E-49 T 13-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 Astex_1732 a78e70b842ce6ff469b9e54d489d079c 268 PRINTS PR00108 Thymidylate synthase family signature 164 190 5.7E-49 T 13-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 Astex_1732 a78e70b842ce6ff469b9e54d489d079c 268 PRINTS PR00108 Thymidylate synthase family signature 47 68 5.7E-49 T 13-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 Astex_1732 a78e70b842ce6ff469b9e54d489d079c 268 PRINTS PR00108 Thymidylate synthase family signature 146 161 5.7E-49 T 13-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 Astex_1732 a78e70b842ce6ff469b9e54d489d079c 268 PRINTS PR00108 Thymidylate synthase family signature 202 219 5.7E-49 T 13-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 Astex_1732 a78e70b842ce6ff469b9e54d489d079c 268 Hamap MF_00008 Thymidylate synthase [thyA]. 6 268 39.423 T 13-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 Astex_1732 a78e70b842ce6ff469b9e54d489d079c 268 ProSitePatterns PS00091 Thymidylate synthase active site. 131 159 - T 13-10-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 Astex_2101 99f7a649c92945b50de4548915a80f65 465 SUPERFAMILY SSF51735 3 106 6.89E-6 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_2101 99f7a649c92945b50de4548915a80f65 465 SUPERFAMILY SSF53790 205 449 7.59E-80 T 13-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 Astex_2101 99f7a649c92945b50de4548915a80f65 465 Pfam PF14824 Sirohaem biosynthesis protein central 113 139 1.4E-7 T 13-10-2018 IPR028281 Siroheme synthase, central domain KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 Astex_2101 99f7a649c92945b50de4548915a80f65 465 Pfam PF10414 Sirohaem synthase dimerisation region 147 196 8.5E-11 T 13-10-2018 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 Astex_2101 99f7a649c92945b50de4548915a80f65 465 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 209 448 5.8E-88 T 13-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 Astex_2101 99f7a649c92945b50de4548915a80f65 465 Gene3D G3DSA:3.30.950.10 325 459 2.4E-39 T 13-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 Astex_2101 99f7a649c92945b50de4548915a80f65 465 Pfam PF13241 Putative NAD(P)-binding 7 109 5.6E-14 T 13-10-2018 Astex_2101 99f7a649c92945b50de4548915a80f65 465 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 211 424 1.4E-50 T 13-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 Astex_2101 99f7a649c92945b50de4548915a80f65 465 Gene3D G3DSA:3.30.160.110 107 142 2.8E-13 T 13-10-2018 Astex_2101 99f7a649c92945b50de4548915a80f65 465 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 4 195 1.7E-42 T 13-10-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 Astex_2101 99f7a649c92945b50de4548915a80f65 465 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 214 228 - T 13-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 Astex_2101 99f7a649c92945b50de4548915a80f65 465 SUPERFAMILY SSF75615 108 202 1.11E-21 T 13-10-2018 Astex_2101 99f7a649c92945b50de4548915a80f65 465 Gene3D G3DSA:3.40.1010.10 207 324 6.1E-45 T 13-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 Astex_2101 99f7a649c92945b50de4548915a80f65 465 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 289 322 - T 13-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 Astex_2101 99f7a649c92945b50de4548915a80f65 465 PIRSF PIRSF036426 1 462 2.7E-153 T 13-10-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 Astex_2101 99f7a649c92945b50de4548915a80f65 465 Gene3D G3DSA:3.40.50.720 1 105 2.9E-12 T 13-10-2018 Astex_2577 5a24e22d525689db84d5f34e2320d4b2 170 Pfam PF05656 Protein of unknown function (DUF805) 7 158 4.2E-14 T 13-10-2018 IPR008523 Protein of unknown function DUF805 GO:0016021 Astex_0171 8835d69dd09f7a5ab87745321bf8ea77 139 SUPERFAMILY SSF47413 7 83 1.79E-25 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Astex_0171 8835d69dd09f7a5ab87745321bf8ea77 139 SMART SM00530 21 76 1.3E-10 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Astex_0171 8835d69dd09f7a5ab87745321bf8ea77 139 Gene3D G3DSA:1.10.260.40 16 99 5.7E-16 T 13-10-2018 Astex_0171 8835d69dd09f7a5ab87745321bf8ea77 139 Pfam PF01381 Helix-turn-helix 23 76 3.9E-10 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Astex_2503 cbd66742ea8a6b2104a7325f7961b25b 880 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 653 704 2.7E-17 T 13-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 Astex_2503 cbd66742ea8a6b2104a7325f7961b25b 880 Gene3D G3DSA:3.30.54.20 624 685 3.0E-45 T 13-10-2018 Astex_2503 cbd66742ea8a6b2104a7325f7961b25b 880 Gene3D G3DSA:3.10.310.40 771 880 3.2E-21 T 13-10-2018 Astex_2503 cbd66742ea8a6b2104a7325f7961b25b 880 Gene3D G3DSA:3.30.980.10 563 705 3.0E-45 T 13-10-2018 Astex_2503 cbd66742ea8a6b2104a7325f7961b25b 880 Pfam PF02272 DHHA1 domain 740 879 1.4E-18 T 13-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 Astex_2503 cbd66742ea8a6b2104a7325f7961b25b 880 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 6 861 3.8E-285 T 13-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 Astex_2503 cbd66742ea8a6b2104a7325f7961b25b 880 SUPERFAMILY SSF55681 3 245 6.21E-109 T 13-10-2018 Astex_2503 cbd66742ea8a6b2104a7325f7961b25b 880 SMART SM00863 653 704 1.1E-19 T 13-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 Astex_2503 cbd66742ea8a6b2104a7325f7961b25b 880 SUPERFAMILY SSF55186 552 716 2.22E-46 T 13-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 Astex_2503 cbd66742ea8a6b2104a7325f7961b25b 880 SUPERFAMILY SSF101353 246 461 3.14E-58 T 13-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 Astex_2503 cbd66742ea8a6b2104a7325f7961b25b 880 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 880 192.421 T 13-10-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 Astex_2503 cbd66742ea8a6b2104a7325f7961b25b 880 Gene3D G3DSA:3.30.930.10 2 242 8.8E-111 T 13-10-2018 Astex_2503 cbd66742ea8a6b2104a7325f7961b25b 880 SUPERFAMILY SSF50447 453 552 2.68E-19 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Astex_2503 cbd66742ea8a6b2104a7325f7961b25b 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 274 290 2.1E-32 T 13-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 Astex_2503 cbd66742ea8a6b2104a7325f7961b25b 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 199 210 2.1E-32 T 13-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 Astex_2503 cbd66742ea8a6b2104a7325f7961b25b 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 75 86 2.1E-32 T 13-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 Astex_2503 cbd66742ea8a6b2104a7325f7961b25b 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 226 239 2.1E-32 T 13-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 Astex_2503 cbd66742ea8a6b2104a7325f7961b25b 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 298 311 2.1E-32 T 13-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 Astex_2503 cbd66742ea8a6b2104a7325f7961b25b 880 Gene3D G3DSA:2.40.30.130 460 552 5.7E-15 T 13-10-2018 Astex_2503 cbd66742ea8a6b2104a7325f7961b25b 880 Pfam PF01411 tRNA synthetases class II (A) 6 554 7.2E-219 T 13-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 Astex_1943 3f799f361763dc35c52bb904f55f5fdf 632 Pfam PF14686 Polysaccharide lyase family 4, domain II 361 425 1.0E-10 T 13-10-2018 IPR029413 Rhamnogalacturonan lyase, domain II MetaCyc: PWY-6769|MetaCyc: PWY-6771 Astex_1943 3f799f361763dc35c52bb904f55f5fdf 632 Pfam PF06045 Rhamnogalacturonate lyase family 131 199 1.3E-6 T 13-10-2018 IPR010325 Rhamnogalacturonate lyase Astex_1943 3f799f361763dc35c52bb904f55f5fdf 632 Pfam PF14683 Polysaccharide lyase family 4, domain III 440 629 1.8E-26 T 13-10-2018 IPR029411 Rhamnogalacturonan lyase, domain III MetaCyc: PWY-6769|MetaCyc: PWY-6771 Astex_1943 3f799f361763dc35c52bb904f55f5fdf 632 SUPERFAMILY SSF49785 438 593 7.23E-13 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_1943 3f799f361763dc35c52bb904f55f5fdf 632 SUPERFAMILY SSF74650 139 313 8.16E-6 T 13-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 Astex_1943 3f799f361763dc35c52bb904f55f5fdf 632 Gene3D G3DSA:2.60.40.1120 339 431 9.3E-6 T 13-10-2018 Astex_1943 3f799f361763dc35c52bb904f55f5fdf 632 SUPERFAMILY SSF49452 341 429 2.16E-6 T 13-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 Astex_0678 f040499b1d643c5d2c65108f15932e29 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 241 262 2.7E-73 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Astex_0678 f040499b1d643c5d2c65108f15932e29 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 41 56 2.7E-73 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Astex_0678 f040499b1d643c5d2c65108f15932e29 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 2.7E-73 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Astex_0678 f040499b1d643c5d2c65108f15932e29 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 62 72 2.7E-73 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Astex_0678 f040499b1d643c5d2c65108f15932e29 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 145 169 2.7E-73 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Astex_0678 f040499b1d643c5d2c65108f15932e29 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 130 142 2.7E-73 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Astex_0678 f040499b1d643c5d2c65108f15932e29 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 197 213 2.7E-73 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Astex_0678 f040499b1d643c5d2c65108f15932e29 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 108 116 2.7E-73 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Astex_0678 f040499b1d643c5d2c65108f15932e29 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 276 294 2.7E-73 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Astex_0678 f040499b1d643c5d2c65108f15932e29 328 Gene3D G3DSA:3.50.50.60 10 307 3.8E-115 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_0678 f040499b1d643c5d2c65108f15932e29 328 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 302 2.4E-46 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Astex_0678 f040499b1d643c5d2c65108f15932e29 328 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 7.1E-35 T 13-10-2018 Astex_0678 f040499b1d643c5d2c65108f15932e29 328 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 239 255 7.1E-35 T 13-10-2018 Astex_0678 f040499b1d643c5d2c65108f15932e29 328 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 7.1E-35 T 13-10-2018 Astex_0678 f040499b1d643c5d2c65108f15932e29 328 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 7.1E-35 T 13-10-2018 Astex_0678 f040499b1d643c5d2c65108f15932e29 328 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 288 7.1E-35 T 13-10-2018 Astex_0678 f040499b1d643c5d2c65108f15932e29 328 SUPERFAMILY SSF51905 1 312 3.3E-48 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_0678 f040499b1d643c5d2c65108f15932e29 328 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 137 157 - T 13-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 Astex_0678 f040499b1d643c5d2c65108f15932e29 328 Gene3D G3DSA:3.50.50.60 119 247 3.8E-115 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_0678 f040499b1d643c5d2c65108f15932e29 328 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 8 313 3.0E-117 T 13-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 Astex_3428 18f6adb24b64610f6666abc7c305e5ee 421 Gene3D G3DSA:1.20.1250.20 11 199 7.0E-44 T 13-10-2018 Astex_3428 18f6adb24b64610f6666abc7c305e5ee 421 Pfam PF07690 Major Facilitator Superfamily 22 369 9.0E-49 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Astex_3428 18f6adb24b64610f6666abc7c305e5ee 421 SUPERFAMILY SSF103473 5 417 5.49E-67 T 13-10-2018 IPR036259 MFS transporter superfamily Astex_3428 18f6adb24b64610f6666abc7c305e5ee 421 Gene3D G3DSA:1.20.1250.20 213 417 8.9E-24 T 13-10-2018 Astex_0976 6d86050ce361d1ed8a9f55890628cea8 471 Gene3D G3DSA:2.30.42.10 271 368 1.6E-25 T 13-10-2018 Astex_0976 6d86050ce361d1ed8a9f55890628cea8 471 Gene3D G3DSA:2.30.42.10 381 471 3.3E-15 T 13-10-2018 Astex_0976 6d86050ce361d1ed8a9f55890628cea8 471 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 52 469 8.7E-130 T 13-10-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 Astex_0976 6d86050ce361d1ed8a9f55890628cea8 471 PRINTS PR00834 HtrA/DegQ protease family signature 226 243 5.5E-49 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Astex_0976 6d86050ce361d1ed8a9f55890628cea8 471 PRINTS PR00834 HtrA/DegQ protease family signature 204 221 5.5E-49 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Astex_0976 6d86050ce361d1ed8a9f55890628cea8 471 PRINTS PR00834 HtrA/DegQ protease family signature 313 325 5.5E-49 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Astex_0976 6d86050ce361d1ed8a9f55890628cea8 471 PRINTS PR00834 HtrA/DegQ protease family signature 128 148 5.5E-49 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Astex_0976 6d86050ce361d1ed8a9f55890628cea8 471 PRINTS PR00834 HtrA/DegQ protease family signature 170 194 5.5E-49 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Astex_0976 6d86050ce361d1ed8a9f55890628cea8 471 PRINTS PR00834 HtrA/DegQ protease family signature 107 119 5.5E-49 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Astex_0976 6d86050ce361d1ed8a9f55890628cea8 471 Pfam PF13180 PDZ domain 296 361 5.6E-15 T 13-10-2018 IPR001478 PDZ domain GO:0005515 Astex_0976 6d86050ce361d1ed8a9f55890628cea8 471 Pfam PF13180 PDZ domain 385 469 1.2E-6 T 13-10-2018 IPR001478 PDZ domain GO:0005515 Astex_0976 6d86050ce361d1ed8a9f55890628cea8 471 Gene3D G3DSA:2.40.10.120 50 264 2.6E-70 T 13-10-2018 Astex_0976 6d86050ce361d1ed8a9f55890628cea8 471 SMART SM00228 273 355 1.7E-14 T 13-10-2018 IPR001478 PDZ domain GO:0005515 Astex_0976 6d86050ce361d1ed8a9f55890628cea8 471 SMART SM00228 382 464 0.025 T 13-10-2018 IPR001478 PDZ domain GO:0005515 Astex_0976 6d86050ce361d1ed8a9f55890628cea8 471 SUPERFAMILY SSF50156 382 469 2.23E-15 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 Astex_0976 6d86050ce361d1ed8a9f55890628cea8 471 SUPERFAMILY SSF50494 51 262 1.24E-55 T 13-10-2018 IPR009003 Peptidase S1, PA clan Astex_0976 6d86050ce361d1ed8a9f55890628cea8 471 SUPERFAMILY SSF50156 223 366 9.6E-23 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 Astex_0976 6d86050ce361d1ed8a9f55890628cea8 471 Pfam PF13365 Trypsin-like peptidase domain 98 233 1.0E-33 T 13-10-2018 Astex_3498 98680cb7225a53a105dab744477d73e9 290 Pfam PF13344 Haloacid dehalogenase-like hydrolase 20 119 4.7E-16 T 13-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA Astex_3498 98680cb7225a53a105dab744477d73e9 290 TIGRFAM TIGR01459 HAD-SF-IIA-hyp4: HAD hydrolase, TIGR01459 family 11 250 1.8E-48 T 13-10-2018 IPR006356 HAD-superfamily hydrolase, subfamily IIA, hypothetical 3 Astex_3498 98680cb7225a53a105dab744477d73e9 290 Pfam PF13242 HAD-hyrolase-like 197 264 1.9E-9 T 13-10-2018 Astex_3498 98680cb7225a53a105dab744477d73e9 290 Gene3D G3DSA:3.40.50.1000 18 255 3.2E-50 T 13-10-2018 IPR023214 HAD superfamily Astex_3498 98680cb7225a53a105dab744477d73e9 290 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 20 252 1.1E-36 T 13-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA Astex_3498 98680cb7225a53a105dab744477d73e9 290 SUPERFAMILY SSF56784 17 262 3.27E-44 T 13-10-2018 IPR036412 HAD-like superfamily Astex_3498 98680cb7225a53a105dab744477d73e9 290 Gene3D G3DSA:3.40.50.1000 85 197 3.2E-50 T 13-10-2018 IPR023214 HAD superfamily Astex_1140 cd9f18f04cafd5ba323ffe04f4fcb95d 159 Pfam PF00588 SpoU rRNA Methylase family 2 142 3.2E-27 T 13-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 Astex_1140 cd9f18f04cafd5ba323ffe04f4fcb95d 159 PIRSF PIRSF029256 1 154 6.2E-51 T 13-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 Astex_1140 cd9f18f04cafd5ba323ffe04f4fcb95d 159 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 1 152 29.245 T 13-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 Astex_1140 cd9f18f04cafd5ba323ffe04f4fcb95d 159 SUPERFAMILY SSF75217 2 150 5.49E-35 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases Astex_1140 cd9f18f04cafd5ba323ffe04f4fcb95d 159 Gene3D G3DSA:3.40.1280.10 1 156 8.0E-49 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Astex_3010 b5dc406d01b74a8b9f1713fadd323eaf 272 Pfam PF09923 Uncharacterized protein conserved in bacteria (DUF2155) 162 260 9.6E-27 T 13-10-2018 IPR019225 Protein of unknown function DUF2155 Astex_1704 01fd5e6f4b42d15d59ebe91a2964cc4d 166 TIGRFAM TIGR02444 TIGR02444: TIGR02444 family protein 5 117 6.1E-31 T 13-10-2018 IPR012659 Conserved hypothetical protein CHP02444 Astex_1704 01fd5e6f4b42d15d59ebe91a2964cc4d 166 Pfam PF09523 Protein of unknown function (DUF2390) 6 114 2.6E-29 T 13-10-2018 IPR012659 Conserved hypothetical protein CHP02444 Astex_2921 256bd432e0e54dc64d83b6cfc9112aff 338 TIGRFAM TIGR03182 PDH_E1_alph_y: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 22 335 2.2E-153 T 13-10-2018 IPR017597 Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y GO:0004739|GO:0006086|GO:0043231 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-70268 Astex_2921 256bd432e0e54dc64d83b6cfc9112aff 338 SUPERFAMILY SSF52518 18 337 5.11E-107 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold Astex_2921 256bd432e0e54dc64d83b6cfc9112aff 338 Gene3D G3DSA:3.40.50.970 2 338 1.7E-133 T 13-10-2018 Astex_2921 256bd432e0e54dc64d83b6cfc9112aff 338 Pfam PF00676 Dehydrogenase E1 component 31 327 1.9E-106 T 13-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 Astex_1002 06cfe86ab7d49fc43fb6865ba2885a6a 338 Gene3D G3DSA:3.30.450.20 120 200 5.4E-6 T 13-10-2018 Astex_1002 06cfe86ab7d49fc43fb6865ba2885a6a 338 SUPERFAMILY SSF55874 188 334 3.14E-13 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_1002 06cfe86ab7d49fc43fb6865ba2885a6a 338 Gene3D G3DSA:3.30.565.10 205 337 1.5E-22 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_1002 06cfe86ab7d49fc43fb6865ba2885a6a 338 Pfam PF07568 Histidine kinase 148 221 5.0E-15 T 13-10-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain Astex_1002 06cfe86ab7d49fc43fb6865ba2885a6a 338 Gene3D G3DSA:1.20.120.620 23 119 2.2E-7 T 13-10-2018 IPR038318 KdpD, transmembrane domain superfamily Astex_1002 06cfe86ab7d49fc43fb6865ba2885a6a 338 Pfam PF13493 Domain of unknown function (DUF4118) 26 126 1.3E-19 T 13-10-2018 IPR025201 Sensor protein KdpD, transmembrane domain Astex_1002 06cfe86ab7d49fc43fb6865ba2885a6a 338 SMART SM00387 245 338 0.0074 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_2748 f39867268cebc2d287f96bc29b168e5a 340 SMART SM00342 232 315 2.2E-30 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Astex_2748 f39867268cebc2d287f96bc29b168e5a 340 SUPERFAMILY SSF46689 268 320 3.14E-11 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Astex_2748 f39867268cebc2d287f96bc29b168e5a 340 Gene3D G3DSA:1.10.10.60 212 320 1.1E-29 T 13-10-2018 Astex_2748 f39867268cebc2d287f96bc29b168e5a 340 Gene3D G3DSA:3.40.50.880 6 211 6.3E-55 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Astex_2748 f39867268cebc2d287f96bc29b168e5a 340 Pfam PF01965 DJ-1/PfpI family 10 176 5.3E-18 T 13-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 Astex_2748 f39867268cebc2d287f96bc29b168e5a 340 SUPERFAMILY SSF46689 216 266 7.77E-11 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Astex_2748 f39867268cebc2d287f96bc29b168e5a 340 Pfam PF12833 Helix-turn-helix domain 238 316 3.0E-24 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Astex_2748 f39867268cebc2d287f96bc29b168e5a 340 SUPERFAMILY SSF52317 9 197 6.27E-45 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Astex_3247 08bf914fa8eb1fcbf62041cc3153ceba 754 Pfam PF05524 PEP-utilising enzyme, N-terminal 188 306 7.3E-21 T 13-10-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 Astex_3247 08bf914fa8eb1fcbf62041cc3153ceba 754 Gene3D G3DSA:3.30.450.40 11 168 1.4E-39 T 13-10-2018 IPR029016 GAF-like domain superfamily Astex_3247 08bf914fa8eb1fcbf62041cc3153ceba 754 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 430 719 3.7E-90 T 13-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 Astex_3247 08bf914fa8eb1fcbf62041cc3153ceba 754 Pfam PF13185 GAF domain 30 162 4.4E-17 T 13-10-2018 IPR003018 GAF domain GO:0005515 Astex_3247 08bf914fa8eb1fcbf62041cc3153ceba 754 SUPERFAMILY SSF55781 12 162 2.84E-29 T 13-10-2018 Astex_3247 08bf914fa8eb1fcbf62041cc3153ceba 754 SUPERFAMILY SSF52009 305 417 3.92E-29 T 13-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 Astex_3247 08bf914fa8eb1fcbf62041cc3153ceba 754 SUPERFAMILY SSF51621 429 726 1.02E-93 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 Astex_3247 08bf914fa8eb1fcbf62041cc3153ceba 754 Gene3D G3DSA:3.50.30.10 191 414 4.0E-54 T 13-10-2018 Astex_3247 08bf914fa8eb1fcbf62041cc3153ceba 754 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 187 733 5.9E-128 T 13-10-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 Astex_3247 08bf914fa8eb1fcbf62041cc3153ceba 754 SUPERFAMILY SSF47831 204 323 3.14E-25 T 13-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 Astex_3247 08bf914fa8eb1fcbf62041cc3153ceba 754 SMART SM00065 28 173 2.7E-15 T 13-10-2018 IPR003018 GAF domain GO:0005515 Astex_3247 08bf914fa8eb1fcbf62041cc3153ceba 754 Gene3D G3DSA:3.20.20.60 417 745 3.8E-98 T 13-10-2018 Astex_3247 08bf914fa8eb1fcbf62041cc3153ceba 754 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 643 658 1.5E-18 T 13-10-2018 Astex_3247 08bf914fa8eb1fcbf62041cc3153ceba 754 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 472 491 1.5E-18 T 13-10-2018 Astex_3247 08bf914fa8eb1fcbf62041cc3153ceba 754 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 679 691 1.5E-18 T 13-10-2018 Astex_3247 08bf914fa8eb1fcbf62041cc3153ceba 754 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 626 641 1.5E-18 T 13-10-2018 Astex_3247 08bf914fa8eb1fcbf62041cc3153ceba 754 Gene3D G3DSA:1.10.274.10 206 326 4.0E-54 T 13-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 Astex_3247 08bf914fa8eb1fcbf62041cc3153ceba 754 Pfam PF00391 PEP-utilising enzyme, mobile domain 331 404 1.0E-20 T 13-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 Astex_3185 3411b9133531c64ab4e0c2fcef350174 118 TIGRFAM TIGR04433 UrcA_uranyl: UrcA family protein 5 89 6.9E-18 T 13-10-2018 IPR030972 UrcA family protein Astex_3720 b510229318226f4b0c8c2c5ce28e6cf6 565 Gene3D G3DSA:3.30.300.160 76 154 2.7E-8 T 13-10-2018 Astex_3720 b510229318226f4b0c8c2c5ce28e6cf6 565 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 56 153 4.1E-14 T 13-10-2018 IPR007831 General secretory system II, protein E, N-terminal Astex_3720 b510229318226f4b0c8c2c5ce28e6cf6 565 SUPERFAMILY SSF52540 181 562 2.91E-88 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_3720 b510229318226f4b0c8c2c5ce28e6cf6 565 Gene3D G3DSA:3.30.450.90 162 289 1.0E-39 T 13-10-2018 Astex_3720 b510229318226f4b0c8c2c5ce28e6cf6 565 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 384 398 - T 13-10-2018 IPR001482 Type II/IV secretion system protein Astex_3720 b510229318226f4b0c8c2c5ce28e6cf6 565 Gene3D G3DSA:3.40.50.300 292 564 3.3E-94 T 13-10-2018 Astex_3720 b510229318226f4b0c8c2c5ce28e6cf6 565 SMART SM00382 317 488 6.4E-4 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_3720 b510229318226f4b0c8c2c5ce28e6cf6 565 Pfam PF00437 Type II/IV secretion system protein 195 456 3.0E-74 T 13-10-2018 IPR001482 Type II/IV secretion system protein Astex_3720 b510229318226f4b0c8c2c5ce28e6cf6 565 SUPERFAMILY SSF160246 17 153 1.33E-21 T 13-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily Astex_1343 ea04ff7d888d83bdc89d84805e48baf1 329 Gene3D G3DSA:1.10.260.40 3 64 7.8E-17 T 13-10-2018 Astex_1343 ea04ff7d888d83bdc89d84805e48baf1 329 Pfam PF00356 Bacterial regulatory proteins, lacI family 12 57 2.1E-9 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Astex_1343 ea04ff7d888d83bdc89d84805e48baf1 329 Gene3D G3DSA:3.40.50.2300 164 288 8.6E-62 T 13-10-2018 Astex_1343 ea04ff7d888d83bdc89d84805e48baf1 329 SUPERFAMILY SSF47413 9 68 2.25E-13 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Astex_1343 ea04ff7d888d83bdc89d84805e48baf1 329 Gene3D G3DSA:3.40.50.2300 65 305 8.6E-62 T 13-10-2018 Astex_1343 ea04ff7d888d83bdc89d84805e48baf1 329 SMART SM00354 10 80 8.9E-19 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Astex_1343 ea04ff7d888d83bdc89d84805e48baf1 329 SUPERFAMILY SSF53822 70 326 1.26E-58 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Astex_1343 ea04ff7d888d83bdc89d84805e48baf1 329 Pfam PF13377 Periplasmic binding protein-like domain 173 325 1.7E-30 T 13-10-2018 Astex_1343 ea04ff7d888d83bdc89d84805e48baf1 329 ProSitePatterns PS00356 LacI-type HTH domain signature. 13 31 - T 13-10-2018 Astex_2746 09b8c356d9f0b9cd0b8a0a092cc6ecb1 228 Pfam PF00687 Ribosomal protein L1p/L10e family 29 218 3.1E-58 T 13-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein Astex_2746 09b8c356d9f0b9cd0b8a0a092cc6ecb1 228 PIRSF PIRSF002155 1 225 1.1E-78 T 13-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_2746 09b8c356d9f0b9cd0b8a0a092cc6ecb1 228 Gene3D G3DSA:3.40.50.790 66 157 1.2E-82 T 13-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich Astex_2746 09b8c356d9f0b9cd0b8a0a092cc6ecb1 228 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 4 226 9.3E-99 T 13-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 Astex_2746 09b8c356d9f0b9cd0b8a0a092cc6ecb1 228 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 227 42.587 T 13-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 Astex_2746 09b8c356d9f0b9cd0b8a0a092cc6ecb1 228 Gene3D G3DSA:3.30.190.20 21 223 1.2E-82 T 13-10-2018 Astex_2746 09b8c356d9f0b9cd0b8a0a092cc6ecb1 228 SUPERFAMILY SSF56808 13 224 8.24E-83 T 13-10-2018 IPR023674 Ribosomal protein L1-like Astex_2746 09b8c356d9f0b9cd0b8a0a092cc6ecb1 228 ProSitePatterns PS01199 Ribosomal protein L1 signature. 118 137 - T 13-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_1602 a900bfef45fafcb2d8ed214ef980b4c6 103 SMART SM00450 6 100 2.1E-17 T 13-10-2018 IPR001763 Rhodanese-like domain Astex_1602 a900bfef45fafcb2d8ed214ef980b4c6 103 SUPERFAMILY SSF52821 2 102 1.01E-26 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily Astex_1602 a900bfef45fafcb2d8ed214ef980b4c6 103 Pfam PF00581 Rhodanese-like domain 7 96 1.1E-12 T 13-10-2018 IPR001763 Rhodanese-like domain Astex_1602 a900bfef45fafcb2d8ed214ef980b4c6 103 Gene3D G3DSA:3.40.250.10 1 103 1.2E-24 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily Astex_3693 ff50eefc9751f0b183dfc1437bcb0786 1021 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 169 1020 2.8E-107 T 13-10-2018 IPR010104 Bacterial TonB-dependent receptor Astex_3693 ff50eefc9751f0b183dfc1437bcb0786 1021 SUPERFAMILY SSF56935 126 1021 2.6E-58 T 13-10-2018 Astex_3693 ff50eefc9751f0b183dfc1437bcb0786 1021 Pfam PF00593 TonB dependent receptor 532 1019 4.3E-30 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_3693 ff50eefc9751f0b183dfc1437bcb0786 1021 Gene3D G3DSA:3.55.50.30 29 127 2.6E-17 T 13-10-2018 Astex_3693 ff50eefc9751f0b183dfc1437bcb0786 1021 Pfam PF07715 TonB-dependent Receptor Plug Domain 157 258 1.5E-11 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_3693 ff50eefc9751f0b183dfc1437bcb0786 1021 Gene3D G3DSA:2.170.130.10 128 266 2.9E-8 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_3693 ff50eefc9751f0b183dfc1437bcb0786 1021 SMART SM00965 58 109 1.1E-5 T 13-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 Astex_3693 ff50eefc9751f0b183dfc1437bcb0786 1021 Gene3D G3DSA:2.40.170.20 555 1020 3.2E-36 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_0091 3bed363b20cba08350dd812cf88b603c 541 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 101 540 8.9E-188 T 13-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Astex_0091 3bed363b20cba08350dd812cf88b603c 541 SUPERFAMILY SSF53738 356 464 3.65E-34 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Astex_0091 3bed363b20cba08350dd812cf88b603c 541 SUPERFAMILY SSF53738 93 264 4.32E-47 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Astex_0091 3bed363b20cba08350dd812cf88b603c 541 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 98 230 8.3E-42 T 13-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Astex_0091 3bed363b20cba08350dd812cf88b603c 541 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 256 352 1.8E-17 T 13-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Astex_0091 3bed363b20cba08350dd812cf88b603c 541 SMART SM00530 8 63 1.8E-5 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Astex_0091 3bed363b20cba08350dd812cf88b603c 541 Gene3D G3DSA:3.40.120.10 272 461 1.3E-68 T 13-10-2018 Astex_0091 3bed363b20cba08350dd812cf88b603c 541 Gene3D G3DSA:3.30.310.50 469 541 8.0E-23 T 13-10-2018 Astex_0091 3bed363b20cba08350dd812cf88b603c 541 Pfam PF01381 Helix-turn-helix 15 57 5.3E-5 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Astex_0091 3bed363b20cba08350dd812cf88b603c 541 Gene3D G3DSA:3.40.120.10 97 245 1.7E-46 T 13-10-2018 Astex_0091 3bed363b20cba08350dd812cf88b603c 541 SUPERFAMILY SSF55957 457 540 4.97E-21 T 13-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Astex_0091 3bed363b20cba08350dd812cf88b603c 541 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 97 538 46.507 T 13-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Astex_0091 3bed363b20cba08350dd812cf88b603c 541 Gene3D G3DSA:3.40.120.10 355 438 1.3E-68 T 13-10-2018 Astex_0091 3bed363b20cba08350dd812cf88b603c 541 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 473 539 4.4E-16 T 13-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Astex_0091 3bed363b20cba08350dd812cf88b603c 541 SUPERFAMILY SSF53738 255 354 5.49E-26 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Astex_0091 3bed363b20cba08350dd812cf88b603c 541 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 356 464 2.7E-36 T 13-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Astex_0091 3bed363b20cba08350dd812cf88b603c 541 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 191 205 1.6E-11 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Astex_0091 3bed363b20cba08350dd812cf88b603c 541 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 272 291 1.6E-11 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Astex_0091 3bed363b20cba08350dd812cf88b603c 541 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 332 347 1.6E-11 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Astex_0091 3bed363b20cba08350dd812cf88b603c 541 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 192 201 - T 13-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Astex_2825 d107d7464be4b21a8d3206c78f758c2c 184 Gene3D G3DSA:2.40.50.140 7 95 2.3E-16 T 13-10-2018 Astex_2825 d107d7464be4b21a8d3206c78f758c2c 184 Gene3D G3DSA:2.40.50.140 115 183 3.9E-13 T 13-10-2018 Astex_2825 d107d7464be4b21a8d3206c78f758c2c 184 Pfam PF00313 'Cold-shock' DNA-binding domain 118 179 2.7E-11 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Astex_2825 d107d7464be4b21a8d3206c78f758c2c 184 Pfam PF00313 'Cold-shock' DNA-binding domain 17 83 2.1E-9 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Astex_2825 d107d7464be4b21a8d3206c78f758c2c 184 SUPERFAMILY SSF50249 117 179 1.16E-14 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Astex_2825 d107d7464be4b21a8d3206c78f758c2c 184 PRINTS PR00050 Cold shock protein signature 118 133 1.6E-7 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Astex_2825 d107d7464be4b21a8d3206c78f758c2c 184 PRINTS PR00050 Cold shock protein signature 139 148 1.6E-7 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Astex_2825 d107d7464be4b21a8d3206c78f758c2c 184 PRINTS PR00050 Cold shock protein signature 154 172 1.6E-7 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Astex_2825 d107d7464be4b21a8d3206c78f758c2c 184 SMART SM00357 17 85 2.0E-7 T 13-10-2018 IPR011129 Cold shock domain GO:0003676 Astex_2825 d107d7464be4b21a8d3206c78f758c2c 184 SMART SM00357 117 181 1.5E-9 T 13-10-2018 IPR011129 Cold shock domain GO:0003676 Astex_2825 d107d7464be4b21a8d3206c78f758c2c 184 SUPERFAMILY SSF50249 16 84 4.07E-12 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Astex_2983 93bc79dacf19851975536dc96fbca797 825 PIRSF PIRSF005496 1 825 6.0E-288 T 13-10-2018 Astex_2983 93bc79dacf19851975536dc96fbca797 825 TIGRFAM TIGR01970 DEAH_box_HrpB: ATP-dependent helicase HrpB 2 824 1.3E-278 T 13-10-2018 IPR010225 ATP-dependent helicase HrpB GO:0008026 Astex_2983 93bc79dacf19851975536dc96fbca797 825 SMART SM00847 392 482 9.0E-13 T 13-10-2018 IPR007502 Helicase-associated domain GO:0004386 Astex_2983 93bc79dacf19851975536dc96fbca797 825 SUPERFAMILY SSF52540 12 343 3.66E-46 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2983 93bc79dacf19851975536dc96fbca797 825 SMART SM00490 229 332 6.2E-12 T 13-10-2018 IPR001650 Helicase, C-terminal Astex_2983 93bc79dacf19851975536dc96fbca797 825 Pfam PF00271 Helicase conserved C-terminal domain 212 331 2.0E-11 T 13-10-2018 IPR001650 Helicase, C-terminal Astex_2983 93bc79dacf19851975536dc96fbca797 825 Pfam PF04408 Helicase associated domain (HA2) 393 459 8.9E-10 T 13-10-2018 IPR007502 Helicase-associated domain GO:0004386 Astex_2983 93bc79dacf19851975536dc96fbca797 825 Pfam PF08482 ATP-dependent helicase C-terminal 680 811 1.5E-46 T 13-10-2018 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal Astex_2983 93bc79dacf19851975536dc96fbca797 825 SMART SM00487 3 185 1.5E-12 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Astex_2983 93bc79dacf19851975536dc96fbca797 825 Gene3D G3DSA:3.40.50.300 1 178 1.5E-49 T 13-10-2018 Astex_2983 93bc79dacf19851975536dc96fbca797 825 Gene3D G3DSA:1.20.120.1080 373 477 2.2E-10 T 13-10-2018 Astex_2983 93bc79dacf19851975536dc96fbca797 825 Gene3D G3DSA:3.40.50.300 179 349 1.1E-44 T 13-10-2018 Astex_2983 93bc79dacf19851975536dc96fbca797 825 Pfam PF00270 DEAD/DEAH box helicase 18 163 3.6E-6 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Astex_0952 9702d245d540ea2fcc44e2d1aaade58f 142 Gene3D G3DSA:3.90.1170.10 1 140 9.7E-57 T 13-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 Astex_0952 9702d245d540ea2fcc44e2d1aaade58f 142 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 13-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_0952 9702d245d540ea2fcc44e2d1aaade58f 142 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 8.0E-50 T 13-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 Astex_0952 9702d245d540ea2fcc44e2d1aaade58f 142 PRINTS PR00060 Ribosomal protein L16 signature 58 87 1.6E-37 T 13-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0952 9702d245d540ea2fcc44e2d1aaade58f 142 PRINTS PR00060 Ribosomal protein L16 signature 88 117 1.6E-37 T 13-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0952 9702d245d540ea2fcc44e2d1aaade58f 142 PRINTS PR00060 Ribosomal protein L16 signature 42 53 1.6E-37 T 13-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0952 9702d245d540ea2fcc44e2d1aaade58f 142 PRINTS PR00060 Ribosomal protein L16 signature 24 36 1.6E-37 T 13-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0952 9702d245d540ea2fcc44e2d1aaade58f 142 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 37.836 T 13-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0952 9702d245d540ea2fcc44e2d1aaade58f 142 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 13-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_0952 9702d245d540ea2fcc44e2d1aaade58f 142 SUPERFAMILY SSF54686 1 134 1.83E-55 T 13-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 Astex_0952 9702d245d540ea2fcc44e2d1aaade58f 142 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 4.9E-56 T 13-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0648 637f517ca45181ef7587e90e9824540a 1075 SUPERFAMILY SSF82714 738 829 1.44E-7 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Astex_0648 637f517ca45181ef7587e90e9824540a 1075 Gene3D G3DSA:3.30.70.1440 687 906 2.7E-223 T 13-10-2018 Astex_0648 637f517ca45181ef7587e90e9824540a 1075 Gene3D G3DSA:3.30.70.1430 48 839 2.7E-223 T 13-10-2018 Astex_0648 637f517ca45181ef7587e90e9824540a 1075 SUPERFAMILY SSF82866 828 1067 3.92E-43 T 13-10-2018 Astex_0648 637f517ca45181ef7587e90e9824540a 1075 PRINTS PR00702 Acriflavin resistance protein family signature 484 507 2.5E-24 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_0648 637f517ca45181ef7587e90e9824540a 1075 PRINTS PR00702 Acriflavin resistance protein family signature 18 42 2.5E-24 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_0648 637f517ca45181ef7587e90e9824540a 1075 PRINTS PR00702 Acriflavin resistance protein family signature 404 428 2.5E-24 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_0648 637f517ca45181ef7587e90e9824540a 1075 PRINTS PR00702 Acriflavin resistance protein family signature 46 64 2.5E-24 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_0648 637f517ca45181ef7587e90e9824540a 1075 PRINTS PR00702 Acriflavin resistance protein family signature 459 482 2.5E-24 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_0648 637f517ca45181ef7587e90e9824540a 1075 PRINTS PR00702 Acriflavin resistance protein family signature 376 397 2.5E-24 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_0648 637f517ca45181ef7587e90e9824540a 1075 Gene3D G3DSA:3.30.2090.10 190 280 2.7E-223 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Astex_0648 637f517ca45181ef7587e90e9824540a 1075 SUPERFAMILY SSF82714 195 273 1.11E-11 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Astex_0648 637f517ca45181ef7587e90e9824540a 1075 SUPERFAMILY SSF82693 48 142 1.23E-16 T 13-10-2018 Astex_0648 637f517ca45181ef7587e90e9824540a 1075 SUPERFAMILY SSF82693 156 342 2.04E-9 T 13-10-2018 Astex_0648 637f517ca45181ef7587e90e9824540a 1075 Gene3D G3DSA:3.30.2090.10 737 831 2.7E-223 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Astex_0648 637f517ca45181ef7587e90e9824540a 1075 Pfam PF00873 AcrB/AcrD/AcrF family 24 1066 8.1E-150 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_0648 637f517ca45181ef7587e90e9824540a 1075 SUPERFAMILY SSF82866 313 511 3.27E-37 T 13-10-2018 Astex_0648 637f517ca45181ef7587e90e9824540a 1075 SUPERFAMILY SSF82693 576 674 3.4E-9 T 13-10-2018 Astex_0648 637f517ca45181ef7587e90e9824540a 1075 Gene3D G3DSA:1.20.1640.10 529 1062 2.7E-223 T 13-10-2018 Astex_0648 637f517ca45181ef7587e90e9824540a 1075 Gene3D G3DSA:1.20.1640.10 24 528 2.7E-223 T 13-10-2018 Astex_0648 637f517ca45181ef7587e90e9824540a 1075 Gene3D G3DSA:3.30.70.1320 142 346 2.7E-223 T 13-10-2018 Astex_0648 637f517ca45181ef7587e90e9824540a 1075 Gene3D G3DSA:3.30.70.1430 578 686 2.7E-223 T 13-10-2018 Astex_0584 becd19dab2a64e1c872527822807e709 184 Gene3D G3DSA:1.10.10.10 21 177 2.8E-40 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_0584 becd19dab2a64e1c872527822807e709 184 SUPERFAMILY SSF46785 23 160 1.43E-32 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_0584 becd19dab2a64e1c872527822807e709 184 Pfam PF01638 HxlR-like helix-turn-helix 37 122 3.1E-21 T 13-10-2018 IPR002577 Helix-turn-helix, HxlR type Astex_1394 b73b72e3932b9c2f8247e6d83697f1ab 186 Pfam PF14279 HNH endonuclease 95 146 1.2E-13 T 13-10-2018 IPR029471 HNH endonuclease 5 Astex_1394 b73b72e3932b9c2f8247e6d83697f1ab 186 Gene3D G3DSA:3.30.40.60 74 163 1.6E-20 T 13-10-2018 Astex_1394 b73b72e3932b9c2f8247e6d83697f1ab 186 SMART SM00507 84 132 7.7E-9 T 13-10-2018 IPR003615 HNH nuclease Astex_1764 2eda286bd83d8e729049099321344fe7 222 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 38 221 36.955 T 13-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 Astex_1764 2eda286bd83d8e729049099321344fe7 222 SUPERFAMILY SSF55620 35 220 2.74E-69 T 13-10-2018 Astex_1764 2eda286bd83d8e729049099321344fe7 222 Gene3D G3DSA:3.30.1130.10 90 222 1.1E-47 T 13-10-2018 Astex_1764 2eda286bd83d8e729049099321344fe7 222 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 44 219 7.2E-60 T 13-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 Astex_1764 2eda286bd83d8e729049099321344fe7 222 Pfam PF01227 GTP cyclohydrolase I 44 220 6.3E-72 T 13-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 Astex_1764 2eda286bd83d8e729049099321344fe7 222 Gene3D G3DSA:1.10.286.10 27 86 3.8E-19 T 13-10-2018 Astex_0757 493036c23afd1542def14f8b678b7f5c 118 Gene3D G3DSA:1.10.760.10 10 117 7.1E-33 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Astex_0757 493036c23afd1542def14f8b678b7f5c 118 SUPERFAMILY SSF46626 18 116 8.65E-27 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Astex_0757 493036c23afd1542def14f8b678b7f5c 118 Pfam PF00034 Cytochrome c 22 116 2.1E-7 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_0757 493036c23afd1542def14f8b678b7f5c 118 PRINTS PR00604 Class IA and IB cytochrome C signature 109 117 9.4E-12 T 13-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_0757 493036c23afd1542def14f8b678b7f5c 118 PRINTS PR00604 Class IA and IB cytochrome C signature 74 90 9.4E-12 T 13-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_0757 493036c23afd1542def14f8b678b7f5c 118 PRINTS PR00604 Class IA and IB cytochrome C signature 30 37 9.4E-12 T 13-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_0757 493036c23afd1542def14f8b678b7f5c 118 PRINTS PR00604 Class IA and IB cytochrome C signature 57 67 9.4E-12 T 13-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_0757 493036c23afd1542def14f8b678b7f5c 118 PRINTS PR00604 Class IA and IB cytochrome C signature 41 56 9.4E-12 T 13-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_0215 48d7434ddc98cb841e1783b89ce75a1c 857 Gene3D G3DSA:3.30.450.20 413 538 5.9E-7 T 13-10-2018 Astex_0215 48d7434ddc98cb841e1783b89ce75a1c 857 SUPERFAMILY SSF47384 538 625 1.02E-15 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Astex_0215 48d7434ddc98cb841e1783b89ce75a1c 857 PRINTS PR00344 Bacterial sensor protein C-terminal signature 760 773 1.3E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_0215 48d7434ddc98cb841e1783b89ce75a1c 857 PRINTS PR00344 Bacterial sensor protein C-terminal signature 725 735 1.3E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_0215 48d7434ddc98cb841e1783b89ce75a1c 857 PRINTS PR00344 Bacterial sensor protein C-terminal signature 736 754 1.3E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_0215 48d7434ddc98cb841e1783b89ce75a1c 857 PRINTS PR00344 Bacterial sensor protein C-terminal signature 707 721 1.3E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_0215 48d7434ddc98cb841e1783b89ce75a1c 857 SUPERFAMILY SSF55785 428 541 2.58E-5 T 13-10-2018 IPR035965 PAS domain superfamily Astex_0215 48d7434ddc98cb841e1783b89ce75a1c 857 Gene3D G3DSA:1.10.287.130 539 627 5.2E-20 T 13-10-2018 Astex_0215 48d7434ddc98cb841e1783b89ce75a1c 857 SUPERFAMILY SSF55874 613 774 3.14E-33 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_0215 48d7434ddc98cb841e1783b89ce75a1c 857 SMART SM00388 552 624 1.6E-17 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_0215 48d7434ddc98cb841e1783b89ce75a1c 857 Gene3D G3DSA:3.30.565.10 630 778 1.2E-34 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_0215 48d7434ddc98cb841e1783b89ce75a1c 857 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 671 774 1.9E-20 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_0215 48d7434ddc98cb841e1783b89ce75a1c 857 SUPERFAMILY SSF55785 272 335 2.09E-6 T 13-10-2018 IPR035965 PAS domain superfamily Astex_0215 48d7434ddc98cb841e1783b89ce75a1c 857 Gene3D G3DSA:3.30.450.20 170 289 1.3E-6 T 13-10-2018 Astex_0215 48d7434ddc98cb841e1783b89ce75a1c 857 SMART SM00387 670 776 5.3E-23 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_0215 48d7434ddc98cb841e1783b89ce75a1c 857 Pfam PF12860 PAS fold 423 536 6.8E-10 T 13-10-2018 Astex_0215 48d7434ddc98cb841e1783b89ce75a1c 857 Pfam PF12860 PAS fold 294 403 7.2E-7 T 13-10-2018 Astex_0215 48d7434ddc98cb841e1783b89ce75a1c 857 Pfam PF00512 His Kinase A (phospho-acceptor) domain 553 624 2.9E-15 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_3078 5eea86c0e0676fb03085d2e6ead4ad97 448 Gene3D G3DSA:3.30.465.10 352 437 1.7E-24 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 Astex_3078 5eea86c0e0676fb03085d2e6ead4ad97 448 SMART SM00116 296 344 0.81 T 13-10-2018 IPR000644 CBS domain Astex_3078 5eea86c0e0676fb03085d2e6ead4ad97 448 SMART SM00116 233 283 13.0 T 13-10-2018 IPR000644 CBS domain Astex_3078 5eea86c0e0676fb03085d2e6ead4ad97 448 SMART SM01091 359 438 2.0E-24 T 13-10-2018 IPR005170 Transporter-associated domain Astex_3078 5eea86c0e0676fb03085d2e6ead4ad97 448 Pfam PF01595 Domain of unknown function DUF21 18 209 8.2E-43 T 13-10-2018 IPR002550 CNNM, transmembrane domain Astex_3078 5eea86c0e0676fb03085d2e6ead4ad97 448 Pfam PF00571 CBS domain 296 344 4.2E-7 T 13-10-2018 IPR000644 CBS domain Astex_3078 5eea86c0e0676fb03085d2e6ead4ad97 448 Pfam PF03471 Transporter associated domain 361 437 1.8E-17 T 13-10-2018 IPR005170 Transporter-associated domain Astex_3078 5eea86c0e0676fb03085d2e6ead4ad97 448 Gene3D G3DSA:3.10.580.10 204 351 3.6E-35 T 13-10-2018 Astex_3078 5eea86c0e0676fb03085d2e6ead4ad97 448 SUPERFAMILY SSF56176 356 446 4.91E-21 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 Astex_3078 5eea86c0e0676fb03085d2e6ead4ad97 448 SUPERFAMILY SSF54631 214 355 3.66E-24 T 13-10-2018 Astex_0210 23f0df7f4d5eba306f9c701e8adb468a 594 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 45 54 - T 13-10-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Astex_0210 23f0df7f4d5eba306f9c701e8adb468a 594 Pfam PF02910 Fumarate reductase flavoprotein C-term 460 594 1.2E-44 T 13-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Astex_0210 23f0df7f4d5eba306f9c701e8adb468a 594 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 9.2E-6 T 13-10-2018 Astex_0210 23f0df7f4d5eba306f9c701e8adb468a 594 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 409 424 9.2E-6 T 13-10-2018 Astex_0210 23f0df7f4d5eba306f9c701e8adb468a 594 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 11 594 1.8E-249 T 13-10-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Astex_0210 23f0df7f4d5eba306f9c701e8adb468a 594 SUPERFAMILY SSF46977 451 594 4.19E-51 T 13-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Astex_0210 23f0df7f4d5eba306f9c701e8adb468a 594 Gene3D G3DSA:1.20.58.100 431 544 3.6E-39 T 13-10-2018 Astex_0210 23f0df7f4d5eba306f9c701e8adb468a 594 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 8 594 4.9E-299 T 13-10-2018 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 Astex_0210 23f0df7f4d5eba306f9c701e8adb468a 594 Gene3D G3DSA:4.10.80.40 545 594 1.1E-12 T 13-10-2018 Astex_0210 23f0df7f4d5eba306f9c701e8adb468a 594 SUPERFAMILY SSF56425 237 355 3.89E-41 T 13-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 Astex_0210 23f0df7f4d5eba306f9c701e8adb468a 594 Pfam PF00890 FAD binding domain 11 405 3.3E-128 T 13-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 Astex_0210 23f0df7f4d5eba306f9c701e8adb468a 594 SUPERFAMILY SSF51905 3 439 3.2E-83 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_0210 23f0df7f4d5eba306f9c701e8adb468a 594 Gene3D G3DSA:3.50.50.60 11 416 9.9E-169 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_0210 23f0df7f4d5eba306f9c701e8adb468a 594 PIRSF PIRSF000171 1 584 3.0E-45 T 13-10-2018 Astex_0210 23f0df7f4d5eba306f9c701e8adb468a 594 Gene3D G3DSA:3.90.700.10 247 350 9.9E-169 T 13-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 Astex_0235 fea2e1b09a1ad1f8153418837ae2ab6c 425 SUPERFAMILY SSF52210 279 423 1.83E-53 T 13-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Astex_0235 fea2e1b09a1ad1f8153418837ae2ab6c 425 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 26 423 7.9E-154 T 13-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 Astex_0235 fea2e1b09a1ad1f8153418837ae2ab6c 425 Gene3D G3DSA:3.30.470.20 26 272 1.1E-87 T 13-10-2018 Astex_0235 fea2e1b09a1ad1f8153418837ae2ab6c 425 Pfam PF08442 ATP-grasp domain 27 240 3.5E-72 T 13-10-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 Astex_0235 fea2e1b09a1ad1f8153418837ae2ab6c 425 Pfam PF00549 CoA-ligase 300 420 8.5E-28 T 13-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Astex_0235 fea2e1b09a1ad1f8153418837ae2ab6c 425 Gene3D G3DSA:3.30.1490.20 46 142 1.1E-87 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 Astex_0235 fea2e1b09a1ad1f8153418837ae2ab6c 425 SUPERFAMILY SSF56059 26 276 6.87E-77 T 13-10-2018 Astex_0235 fea2e1b09a1ad1f8153418837ae2ab6c 425 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 26 424 42.731 T 13-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 Astex_0235 fea2e1b09a1ad1f8153418837ae2ab6c 425 PIRSF PIRSF001554 26 425 1.4E-147 T 13-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 Astex_0235 fea2e1b09a1ad1f8153418837ae2ab6c 425 Gene3D G3DSA:3.40.50.261 278 425 6.9E-56 T 13-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Astex_1823 a6525cea84bd165883afd0790474c549 420 SUPERFAMILY SSF103473 31 417 3.01E-36 T 13-10-2018 IPR036259 MFS transporter superfamily Astex_1823 a6525cea84bd165883afd0790474c549 420 PIRSF PIRSF004925 22 420 4.5E-96 T 13-10-2018 IPR026032 Probable 3-phenylpropionic acid transporter Astex_1823 a6525cea84bd165883afd0790474c549 420 Pfam PF12832 MFS_1 like family 31 392 1.3E-34 T 13-10-2018 IPR024989 Major facilitator superfamily associated domain Astex_1823 a6525cea84bd165883afd0790474c549 420 Gene3D G3DSA:1.20.1250.20 229 419 5.6E-37 T 13-10-2018 Astex_1823 a6525cea84bd165883afd0790474c549 420 Gene3D G3DSA:1.20.1250.20 28 213 5.9E-20 T 13-10-2018 Astex_2735 8b9813b6da8d75de04636232da8f47e1 206 Pfam PF13649 Methyltransferase domain 42 133 2.2E-11 T 13-10-2018 Astex_2735 8b9813b6da8d75de04636232da8f47e1 206 SUPERFAMILY SSF53335 18 182 9.7E-25 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Astex_2735 8b9813b6da8d75de04636232da8f47e1 206 Gene3D G3DSA:3.40.50.150 6 190 2.8E-27 T 13-10-2018 Astex_0047 292e8c4df1b1c80ff05a31f81342306b 203 Pfam PF01725 Ham1 family 11 201 9.2E-50 T 13-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 Astex_0047 292e8c4df1b1c80ff05a31f81342306b 203 SUPERFAMILY SSF52972 8 202 1.2E-58 T 13-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like Astex_0047 292e8c4df1b1c80ff05a31f81342306b 203 Hamap MF_01405 dITP/XTP pyrophosphatase. 9 203 38.243 T 13-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 Astex_0047 292e8c4df1b1c80ff05a31f81342306b 203 Gene3D G3DSA:3.90.950.10 7 203 1.9E-60 T 13-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like Astex_1497 e34ec27dc89537f22a5f124e9b23d709 286 Gene3D G3DSA:3.40.50.620 1 182 7.6E-71 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Astex_1497 e34ec27dc89537f22a5f124e9b23d709 286 SUPERFAMILY SSF52374 10 286 8.34E-103 T 13-10-2018 Astex_1497 e34ec27dc89537f22a5f124e9b23d709 286 Pfam PF02569 Pantoate-beta-alanine ligase 13 284 1.1E-99 T 13-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 Astex_1497 e34ec27dc89537f22a5f124e9b23d709 286 Gene3D G3DSA:3.30.1300.10 183 286 1.1E-28 T 13-10-2018 Astex_1497 e34ec27dc89537f22a5f124e9b23d709 286 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 12 286 3.9E-90 T 13-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 Astex_1497 e34ec27dc89537f22a5f124e9b23d709 286 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 34 87 6.1E-8 T 13-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 Astex_1497 e34ec27dc89537f22a5f124e9b23d709 286 Hamap MF_00158 Pantothenate synthetase [panC]. 10 286 39.342 T 13-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 Astex_0973 a240f538efe89d6dc8fa8c93055236d9 419 SUPERFAMILY SSF103473 11 396 4.45E-62 T 13-10-2018 IPR036259 MFS transporter superfamily Astex_0973 a240f538efe89d6dc8fa8c93055236d9 419 ProSitePatterns PS00216 Sugar transport proteins signature 1. 72 88 - T 13-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Astex_0973 a240f538efe89d6dc8fa8c93055236d9 419 Gene3D G3DSA:1.20.1250.20 7 402 4.3E-71 T 13-10-2018 Astex_0973 a240f538efe89d6dc8fa8c93055236d9 419 Pfam PF07690 Major Facilitator Superfamily 18 362 9.1E-47 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Astex_0973 a240f538efe89d6dc8fa8c93055236d9 419 PRINTS PR01035 Tetracycline resistance protein signature 24 40 4.9E-61 T 13-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Astex_0973 a240f538efe89d6dc8fa8c93055236d9 419 PRINTS PR01035 Tetracycline resistance protein signature 142 164 4.9E-61 T 13-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Astex_0973 a240f538efe89d6dc8fa8c93055236d9 419 PRINTS PR01035 Tetracycline resistance protein signature 112 133 4.9E-61 T 13-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Astex_0973 a240f538efe89d6dc8fa8c93055236d9 419 PRINTS PR01035 Tetracycline resistance protein signature 170 190 4.9E-61 T 13-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Astex_0973 a240f538efe89d6dc8fa8c93055236d9 419 PRINTS PR01035 Tetracycline resistance protein signature 85 109 4.9E-61 T 13-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Astex_0973 a240f538efe89d6dc8fa8c93055236d9 419 PRINTS PR01035 Tetracycline resistance protein signature 286 307 4.9E-61 T 13-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Astex_0973 a240f538efe89d6dc8fa8c93055236d9 419 PRINTS PR01035 Tetracycline resistance protein signature 258 278 4.9E-61 T 13-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Astex_0973 a240f538efe89d6dc8fa8c93055236d9 419 PRINTS PR01035 Tetracycline resistance protein signature 54 73 4.9E-61 T 13-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Astex_0973 a240f538efe89d6dc8fa8c93055236d9 419 PRINTS PR01035 Tetracycline resistance protein signature 346 369 4.9E-61 T 13-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Astex_0695 e86d7d6126c25947330a7e5c682cb1b5 1152 Pfam PF05227 CHASE3 domain 57 189 4.6E-32 T 13-10-2018 IPR007891 CHASE3 Astex_0695 e86d7d6126c25947330a7e5c682cb1b5 1152 PRINTS PR00344 Bacterial sensor protein C-terminal signature 652 662 1.5E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_0695 e86d7d6126c25947330a7e5c682cb1b5 1152 PRINTS PR00344 Bacterial sensor protein C-terminal signature 634 648 1.5E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_0695 e86d7d6126c25947330a7e5c682cb1b5 1152 PRINTS PR00344 Bacterial sensor protein C-terminal signature 693 706 1.5E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_0695 e86d7d6126c25947330a7e5c682cb1b5 1152 PRINTS PR00344 Bacterial sensor protein C-terminal signature 669 687 1.5E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_0695 e86d7d6126c25947330a7e5c682cb1b5 1152 SMART SM00448 1027 1146 1.2E-36 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_0695 e86d7d6126c25947330a7e5c682cb1b5 1152 SMART SM00448 881 995 7.2E-11 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_0695 e86d7d6126c25947330a7e5c682cb1b5 1152 SMART SM00448 759 869 5.1E-18 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_0695 e86d7d6126c25947330a7e5c682cb1b5 1152 SMART SM00387 598 709 4.5E-37 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_0695 e86d7d6126c25947330a7e5c682cb1b5 1152 Gene3D G3DSA:3.30.450.40 230 398 2.8E-13 T 13-10-2018 IPR029016 GAF-like domain superfamily Astex_0695 e86d7d6126c25947330a7e5c682cb1b5 1152 Gene3D G3DSA:1.10.287.130 470 551 1.6E-24 T 13-10-2018 Astex_0695 e86d7d6126c25947330a7e5c682cb1b5 1152 Gene3D G3DSA:1.20.1440.210 63 189 1.9E-28 T 13-10-2018 Astex_0695 e86d7d6126c25947330a7e5c682cb1b5 1152 Gene3D G3DSA:3.30.565.10 552 710 3.8E-49 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_0695 e86d7d6126c25947330a7e5c682cb1b5 1152 SUPERFAMILY SSF52172 879 1001 2.42E-19 T 13-10-2018 IPR011006 CheY-like superfamily Astex_0695 e86d7d6126c25947330a7e5c682cb1b5 1152 SUPERFAMILY SSF52172 1022 1151 8.68E-37 T 13-10-2018 IPR011006 CheY-like superfamily Astex_0695 e86d7d6126c25947330a7e5c682cb1b5 1152 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 599 707 3.2E-29 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_0695 e86d7d6126c25947330a7e5c682cb1b5 1152 Gene3D G3DSA:3.40.50.2300 879 1016 1.3E-17 T 13-10-2018 Astex_0695 e86d7d6126c25947330a7e5c682cb1b5 1152 Pfam PF00512 His Kinase A (phospho-acceptor) domain 484 551 7.9E-19 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_0695 e86d7d6126c25947330a7e5c682cb1b5 1152 SUPERFAMILY SSF52172 760 873 1.28E-25 T 13-10-2018 IPR011006 CheY-like superfamily Astex_0695 e86d7d6126c25947330a7e5c682cb1b5 1152 Pfam PF00072 Response regulator receiver domain 1030 1146 1.1E-26 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_0695 e86d7d6126c25947330a7e5c682cb1b5 1152 Pfam PF00072 Response regulator receiver domain 762 869 2.4E-16 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_0695 e86d7d6126c25947330a7e5c682cb1b5 1152 Pfam PF00072 Response regulator receiver domain 883 985 3.5E-14 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_0695 e86d7d6126c25947330a7e5c682cb1b5 1152 SUPERFAMILY SSF55781 243 413 1.41E-17 T 13-10-2018 Astex_0695 e86d7d6126c25947330a7e5c682cb1b5 1152 SMART SM00388 483 551 2.6E-21 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_0695 e86d7d6126c25947330a7e5c682cb1b5 1152 Gene3D G3DSA:3.40.50.12740 1026 1152 1.1E-41 T 13-10-2018 Astex_0695 e86d7d6126c25947330a7e5c682cb1b5 1152 Gene3D G3DSA:3.40.50.12740 759 878 2.3E-25 T 13-10-2018 Astex_0695 e86d7d6126c25947330a7e5c682cb1b5 1152 SUPERFAMILY SSF47384 472 553 3.34E-21 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Astex_0695 e86d7d6126c25947330a7e5c682cb1b5 1152 SUPERFAMILY SSF55874 540 710 1.96E-48 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_0704 46f38d1271676b28bdbe05cd80eb3fc6 491 SUPERFAMILY SSF51905 5 417 5.18E-30 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_0704 46f38d1271676b28bdbe05cd80eb3fc6 491 Gene3D G3DSA:3.50.50.60 1 489 1.6E-180 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_0704 46f38d1271676b28bdbe05cd80eb3fc6 491 Pfam PF04820 Tryptophan halogenase 6 456 2.1E-182 T 13-10-2018 IPR006905 Flavin-dependent halogenase Astex_0704 46f38d1271676b28bdbe05cd80eb3fc6 491 PIRSF PIRSF011396 1 491 8.7E-184 T 13-10-2018 IPR033856 Flavin-dependent tryptophan halogenase Astex_1807 58825de0a8a6f840c4ab10786417d42c 107 Pfam PF13202 EF hand 45 67 1.2E-5 T 13-10-2018 IPR002048 EF-hand domain GO:0005509 Astex_1807 58825de0a8a6f840c4ab10786417d42c 107 Pfam PF13202 EF hand 73 94 4.5E-6 T 13-10-2018 IPR002048 EF-hand domain GO:0005509 Astex_1807 58825de0a8a6f840c4ab10786417d42c 107 SUPERFAMILY SSF47473 43 95 4.19E-9 T 13-10-2018 IPR011992 EF-hand domain pair Astex_1807 58825de0a8a6f840c4ab10786417d42c 107 ProSitePatterns PS00018 EF-hand calcium-binding domain. 52 64 - T 13-10-2018 IPR018247 EF-Hand 1, calcium-binding site Astex_1807 58825de0a8a6f840c4ab10786417d42c 107 ProSitePatterns PS00018 EF-hand calcium-binding domain. 79 91 - T 13-10-2018 IPR018247 EF-Hand 1, calcium-binding site Astex_1807 58825de0a8a6f840c4ab10786417d42c 107 Gene3D G3DSA:1.10.238.10 32 100 1.0E-13 T 13-10-2018 Astex_1344 8e38dd476f16d1532af6617e44eda0a5 428 SUPERFAMILY SSF103473 20 424 3.27E-59 T 13-10-2018 IPR036259 MFS transporter superfamily Astex_1344 8e38dd476f16d1532af6617e44eda0a5 428 Pfam PF00083 Sugar (and other) transporter 23 421 8.5E-24 T 13-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 Astex_1344 8e38dd476f16d1532af6617e44eda0a5 428 Gene3D G3DSA:1.20.1250.20 19 425 9.3E-56 T 13-10-2018 Astex_1344 8e38dd476f16d1532af6617e44eda0a5 428 ProSitePatterns PS00216 Sugar transport proteins signature 1. 302 319 - T 13-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Astex_1758 5ac251c9620e18f1cd9cfbfebfd3c420 640 SUPERFAMILY SSF81271 3 61 2.68E-12 T 13-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 Astex_1758 5ac251c9620e18f1cd9cfbfebfd3c420 640 Gene3D G3DSA:3.10.20.30 1 62 7.0E-20 T 13-10-2018 IPR012675 Beta-grasp domain superfamily Astex_1758 5ac251c9620e18f1cd9cfbfebfd3c420 640 Gene3D G3DSA:3.30.980.10 69 223 7.9E-59 T 13-10-2018 Astex_1758 5ac251c9620e18f1cd9cfbfebfd3c420 640 SUPERFAMILY SSF55186 64 242 1.2E-59 T 13-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 Astex_1758 5ac251c9620e18f1cd9cfbfebfd3c420 640 SMART SM00863 169 220 1.3E-23 T 13-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 Astex_1758 5ac251c9620e18f1cd9cfbfebfd3c420 640 Pfam PF03129 Anticodon binding domain 543 631 2.5E-19 T 13-10-2018 IPR004154 Anticodon-binding Astex_1758 5ac251c9620e18f1cd9cfbfebfd3c420 640 Pfam PF02824 TGS domain 5 61 1.0E-7 T 13-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 Astex_1758 5ac251c9620e18f1cd9cfbfebfd3c420 640 SUPERFAMILY SSF55681 244 528 1.26E-97 T 13-10-2018 Astex_1758 5ac251c9620e18f1cd9cfbfebfd3c420 640 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 169 220 3.7E-14 T 13-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 Astex_1758 5ac251c9620e18f1cd9cfbfebfd3c420 640 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 633 6.5E-211 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 Astex_1758 5ac251c9620e18f1cd9cfbfebfd3c420 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 331 359 7.1E-55 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 Astex_1758 5ac251c9620e18f1cd9cfbfebfd3c420 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 509 522 7.1E-55 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 Astex_1758 5ac251c9620e18f1cd9cfbfebfd3c420 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 364 387 7.1E-55 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 Astex_1758 5ac251c9620e18f1cd9cfbfebfd3c420 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 466 494 7.1E-55 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 Astex_1758 5ac251c9620e18f1cd9cfbfebfd3c420 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 536 548 7.1E-55 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 Astex_1758 5ac251c9620e18f1cd9cfbfebfd3c420 640 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 321 531 1.8E-42 T 13-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Astex_1758 5ac251c9620e18f1cd9cfbfebfd3c420 640 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 636 32.954 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 Astex_1758 5ac251c9620e18f1cd9cfbfebfd3c420 640 Gene3D G3DSA:3.40.50.800 534 636 8.6E-28 T 13-10-2018 IPR036621 Anticodon-binding domain superfamily Astex_1758 5ac251c9620e18f1cd9cfbfebfd3c420 640 Gene3D G3DSA:3.30.54.20 130 187 7.9E-59 T 13-10-2018 Astex_1758 5ac251c9620e18f1cd9cfbfebfd3c420 640 SUPERFAMILY SSF52954 529 632 4.23E-30 T 13-10-2018 Astex_1758 5ac251c9620e18f1cd9cfbfebfd3c420 640 Gene3D G3DSA:3.30.930.10 224 533 4.9E-120 T 13-10-2018 Astex_2052 7f26a0ace67c0fd574766ebc926018bb 297 PIRSF PIRSF001439 1 296 1.4E-47 T 13-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 Astex_2052 7f26a0ace67c0fd574766ebc926018bb 297 SUPERFAMILY SSF51735 1 294 3.94E-67 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_2052 7f26a0ace67c0fd574766ebc926018bb 297 Gene3D G3DSA:3.30.1780.10 28 291 7.3E-63 T 13-10-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 Astex_2052 7f26a0ace67c0fd574766ebc926018bb 297 Gene3D G3DSA:3.40.50.720 117 279 7.3E-63 T 13-10-2018 Astex_2052 7f26a0ace67c0fd574766ebc926018bb 297 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 42 295 6.1E-42 T 13-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 Astex_3238 048f826b483ff494f7eea41c9cdd5ef4 608 Pfam PF02254 TrkA-N domain 430 543 5.7E-24 T 13-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 Astex_3238 048f826b483ff494f7eea41c9cdd5ef4 608 Gene3D G3DSA:3.40.50.720 428 587 4.9E-33 T 13-10-2018 Astex_3238 048f826b483ff494f7eea41c9cdd5ef4 608 Gene3D G3DSA:1.20.1530.20 22 412 3.8E-71 T 13-10-2018 IPR038770 Sodium/solute symporter superfamily Astex_3238 048f826b483ff494f7eea41c9cdd5ef4 608 Pfam PF00999 Sodium/hydrogen exchanger family 25 399 7.0E-52 T 13-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 Astex_3238 048f826b483ff494f7eea41c9cdd5ef4 608 SUPERFAMILY SSF51735 430 565 1.58E-26 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_3492 d7e2a9738a90b852e818ad5115d196ed 329 Pfam PF06574 FAD synthetase 32 188 4.3E-41 T 13-10-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 Astex_3492 d7e2a9738a90b852e818ad5115d196ed 329 Pfam PF01687 Riboflavin kinase 206 328 9.4E-35 T 13-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 Astex_3492 d7e2a9738a90b852e818ad5115d196ed 329 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 37 328 1.0E-80 T 13-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 Astex_3492 d7e2a9738a90b852e818ad5115d196ed 329 PIRSF PIRSF004491 20 329 6.0E-89 T 13-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 Astex_3492 d7e2a9738a90b852e818ad5115d196ed 329 SUPERFAMILY SSF82114 196 329 2.4E-41 T 13-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 Astex_3492 d7e2a9738a90b852e818ad5115d196ed 329 SMART SM00904 205 329 7.0E-54 T 13-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 Astex_3492 d7e2a9738a90b852e818ad5115d196ed 329 Gene3D G3DSA:3.40.50.620 24 208 8.4E-50 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Astex_3492 d7e2a9738a90b852e818ad5115d196ed 329 SUPERFAMILY SSF52374 35 200 1.38E-26 T 13-10-2018 Astex_3492 d7e2a9738a90b852e818ad5115d196ed 329 Gene3D G3DSA:2.40.30.30 211 329 2.1E-37 T 13-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 Astex_3018 083155d80d9512c3fb100c39b5052f9b 508 Gene3D G3DSA:3.30.420.150 127 309 1.4E-41 T 13-10-2018 Astex_3018 083155d80d9512c3fb100c39b5052f9b 508 SUPERFAMILY SSF53067 22 142 7.51E-33 T 13-10-2018 Astex_3018 083155d80d9512c3fb100c39b5052f9b 508 Pfam PF02541 Ppx/GppA phosphatase family 36 313 3.6E-36 T 13-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 Astex_3018 083155d80d9512c3fb100c39b5052f9b 508 SUPERFAMILY SSF53067 148 314 1.17E-29 T 13-10-2018 Astex_3018 083155d80d9512c3fb100c39b5052f9b 508 Gene3D G3DSA:1.10.3210.10 311 505 9.9E-46 T 13-10-2018 Astex_3018 083155d80d9512c3fb100c39b5052f9b 508 SUPERFAMILY SSF109604 342 497 2.76E-7 T 13-10-2018 Astex_3018 083155d80d9512c3fb100c39b5052f9b 508 Gene3D G3DSA:3.30.420.40 14 126 3.1E-31 T 13-10-2018 Astex_1728 f46310d76a03913f6760ba3069f4516b 286 TIGRFAM TIGR00965 dapD: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 9 285 1.7E-128 T 13-10-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 Astex_1728 f46310d76a03913f6760ba3069f4516b 286 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 185 219 6.3E-13 T 13-10-2018 IPR001451 Hexapeptide repeat Astex_1728 f46310d76a03913f6760ba3069f4516b 286 Gene3D G3DSA:2.160.10.10 97 271 4.0E-55 T 13-10-2018 Astex_1728 f46310d76a03913f6760ba3069f4516b 286 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 144 172 - T 13-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 Astex_1728 f46310d76a03913f6760ba3069f4516b 286 SUPERFAMILY SSF51161 8 270 1.8E-67 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily Astex_1728 f46310d76a03913f6760ba3069f4516b 286 Hamap MF_00811 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 4 286 55.849 T 13-10-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 Astex_1728 f46310d76a03913f6760ba3069f4516b 286 Pfam PF14805 Tetrahydrodipicolinate N-succinyltransferase N-terminal 8 71 1.2E-21 T 13-10-2018 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117 Astex_1728 f46310d76a03913f6760ba3069f4516b 286 Gene3D G3DSA:1.10.166.10 4 72 1.9E-25 T 13-10-2018 IPR037133 Tetrahydrodipicolinate-N-succinyltransferase, N-terminal domain superfamily KEGG: 00300+2.3.1.117 Astex_1728 f46310d76a03913f6760ba3069f4516b 286 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 142 176 1.0E-4 T 13-10-2018 IPR001451 Hexapeptide repeat Astex_0772 fcd1cb110f14f6c21dec25877bc4ffac 339 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 281 294 - T 13-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 Astex_0772 fcd1cb110f14f6c21dec25877bc4ffac 339 Gene3D G3DSA:3.40.1190.20 1 336 6.4E-83 T 13-10-2018 IPR029056 Ribokinase-like Astex_0772 fcd1cb110f14f6c21dec25877bc4ffac 339 SUPERFAMILY SSF53613 4 327 1.03E-73 T 13-10-2018 IPR029056 Ribokinase-like Astex_0772 fcd1cb110f14f6c21dec25877bc4ffac 339 Pfam PF00294 pfkB family carbohydrate kinase 56 324 2.2E-51 T 13-10-2018 IPR011611 Carbohydrate kinase PfkB Astex_3797 85e75a90c95477918464162112e790cd 307 Pfam PF13728 F plasmid transfer operon protein 47 296 2.1E-53 T 13-10-2018 IPR039555 F plasmid transfer operon protein Astex_3797 85e75a90c95477918464162112e790cd 307 SUPERFAMILY SSF52833 167 242 4.56E-6 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Astex_0437 c20332ba551f1abe8ec0e46da6bcab6b 284 Pfam PF08239 Bacterial SH3 domain 45 94 8.7E-8 T 13-10-2018 IPR003646 SH3-like domain, bacterial-type Astex_0437 c20332ba551f1abe8ec0e46da6bcab6b 284 Gene3D G3DSA:3.90.1720.10 161 279 1.5E-27 T 13-10-2018 Astex_0437 c20332ba551f1abe8ec0e46da6bcab6b 284 Pfam PF00877 NlpC/P60 family 175 257 1.0E-15 T 13-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain Astex_0437 c20332ba551f1abe8ec0e46da6bcab6b 284 SUPERFAMILY SSF54001 154 281 1.44E-31 T 13-10-2018 IPR038765 Papain-like cysteine peptidase superfamily Astex_2537 a281bb7e2adbd5fff062e3a198b8d632 391 SMART SM00471 65 218 9.5E-14 T 13-10-2018 IPR003607 HD/PDEase domain Astex_2537 a281bb7e2adbd5fff062e3a198b8d632 391 Pfam PF01966 HD domain 69 208 3.7E-16 T 13-10-2018 IPR006674 HD domain Astex_2537 a281bb7e2adbd5fff062e3a198b8d632 391 Pfam PF13286 Phosphohydrolase-associated domain 295 386 3.2E-29 T 13-10-2018 IPR026875 Phosphohydrolase-associated domain Astex_2537 a281bb7e2adbd5fff062e3a198b8d632 391 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 31 389 5.7E-103 T 13-10-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 Astex_2537 a281bb7e2adbd5fff062e3a198b8d632 391 TIGRFAM TIGR00277 HDIG: HDIG domain 70 106 4.0E-7 T 13-10-2018 IPR006675 HDIG domain Astex_2537 a281bb7e2adbd5fff062e3a198b8d632 391 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 9 388 38.716 T 13-10-2018 IPR023023 dNTP triphosphohydrolase, type 2 GO:0016793 Astex_2537 a281bb7e2adbd5fff062e3a198b8d632 391 Gene3D G3DSA:1.10.3210.10 5 389 6.9E-134 T 13-10-2018 Astex_2537 a281bb7e2adbd5fff062e3a198b8d632 391 SUPERFAMILY SSF109604 20 388 3.87E-86 T 13-10-2018 Astex_2783 8cbb6c607774c683245116e7ec822981 175 Pfam PF00578 AhpC/TSA family 26 153 4.4E-26 T 13-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 Astex_2783 8cbb6c607774c683245116e7ec822981 175 Gene3D G3DSA:3.40.30.10 15 170 3.6E-33 T 13-10-2018 Astex_2783 8cbb6c607774c683245116e7ec822981 175 SUPERFAMILY SSF52833 22 174 2.68E-35 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Astex_2783 8cbb6c607774c683245116e7ec822981 175 PIRSF PIRSF000239 20 162 5.7E-18 T 13-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 Astex_0441 5bbe243e6e6e085399b8a38fd060611c 58 TIGRFAM TIGR03141 cytochro_ccmD: heme exporter protein CcmD 3 46 4.8E-17 T 13-10-2018 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 Astex_0441 5bbe243e6e6e085399b8a38fd060611c 58 Pfam PF04995 Heme exporter protein D (CcmD) 6 45 3.2E-15 T 13-10-2018 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 Astex_1105 8f0920c2cd6e7b342cb519ba8b5f506f 251 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 28 246 2.9E-50 T 13-10-2018 IPR006214 Bax inhibitor 1-related Astex_2804 31e918edca7dee4b59ed2dcb70f835c2 204 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 33 153 8.0E-43 T 13-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2804 31e918edca7dee4b59ed2dcb70f835c2 204 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 34 151 2.7E-44 T 13-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2804 31e918edca7dee4b59ed2dcb70f835c2 204 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 21 160 32.163 T 13-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2804 31e918edca7dee4b59ed2dcb70f835c2 204 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 83 139 5.0E-20 T 13-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2804 31e918edca7dee4b59ed2dcb70f835c2 204 SUPERFAMILY SSF143243 11 185 5.62E-59 T 13-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2804 31e918edca7dee4b59ed2dcb70f835c2 204 Gene3D G3DSA:3.30.460.80 2 132 7.6E-41 T 13-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_3684 a9da02fd5a022a272365709b6642cb70 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 8.5E-10 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_3684 a9da02fd5a022a272365709b6642cb70 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 8.5E-10 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_3684 a9da02fd5a022a272365709b6642cb70 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 8.5E-10 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_3684 a9da02fd5a022a272365709b6642cb70 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Astex_3684 a9da02fd5a022a272365709b6642cb70 248 Gene3D G3DSA:3.40.50.720 2 239 9.8E-58 T 13-10-2018 Astex_3684 a9da02fd5a022a272365709b6642cb70 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 4.5E-23 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_3684 a9da02fd5a022a272365709b6642cb70 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 4.5E-23 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_3684 a9da02fd5a022a272365709b6642cb70 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 4.5E-23 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_3684 a9da02fd5a022a272365709b6642cb70 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 4.5E-23 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_3684 a9da02fd5a022a272365709b6642cb70 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 4.5E-23 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_3684 a9da02fd5a022a272365709b6642cb70 248 SUPERFAMILY SSF51735 6 232 6.28E-57 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_3684 a9da02fd5a022a272365709b6642cb70 248 Pfam PF00106 short chain dehydrogenase 11 204 1.1E-47 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0687 209e40e359fdf3a77bde4d645aa1c37c 288 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 192 210 2.3E-7 T 13-10-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 Astex_0687 209e40e359fdf3a77bde4d645aa1c37c 288 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 87 109 2.3E-7 T 13-10-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 Astex_0687 209e40e359fdf3a77bde4d645aa1c37c 288 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 224 243 2.3E-7 T 13-10-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 Astex_0687 209e40e359fdf3a77bde4d645aa1c37c 288 Gene3D G3DSA:1.10.800.10 6 288 9.0E-102 T 13-10-2018 IPR036951 Aromatic amino acid hydroxylase superfamily GO:0004497|GO:0005506|GO:0009072|GO:0055114 Astex_0687 209e40e359fdf3a77bde4d645aa1c37c 288 Pfam PF00351 Biopterin-dependent aromatic amino acid hydroxylase 31 245 3.5E-46 T 13-10-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 Astex_0687 209e40e359fdf3a77bde4d645aa1c37c 288 SUPERFAMILY SSF56534 19 278 2.35E-96 T 13-10-2018 IPR036329 Aromatic amino acid monoxygenase, C-terminal domain superfamily Astex_0687 209e40e359fdf3a77bde4d645aa1c37c 288 ProSitePatterns PS00367 Biopterin-dependent aromatic amino acid hydroxylases signature. 130 141 - T 13-10-2018 IPR018301 Aromatic amino acid hydroxylase, iron/copper binding site GO:0004497|GO:0005506|GO:0009072|GO:0055114 Astex_0687 209e40e359fdf3a77bde4d645aa1c37c 288 TIGRFAM TIGR01267 Phe4hydrox_mono: phenylalanine-4-hydroxylase 22 262 5.5E-106 T 13-10-2018 IPR005960 Phenylalanine-4-hydroxylase, monomeric form GO:0004505|GO:0006559|GO:0055114 KEGG: 00360+1.14.16.1|KEGG: 00400+1.14.16.1|KEGG: 00790+1.14.16.1|MetaCyc: PWY-6134|MetaCyc: PWY-7158 Astex_2436 80ef99f8053f5250bd77802f4b52ffea 314 Pfam PF16220 Domain of unknown function (DUF4880) 16 52 1.7E-8 T 13-10-2018 IPR032623 FecR, N-terminal Astex_2436 80ef99f8053f5250bd77802f4b52ffea 314 Pfam PF04773 FecR protein 111 198 6.4E-11 T 13-10-2018 IPR006860 FecR protein Astex_2436 80ef99f8053f5250bd77802f4b52ffea 314 PIRSF PIRSF018266 7 314 2.4E-49 T 13-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component Astex_2436 80ef99f8053f5250bd77802f4b52ffea 314 Gene3D G3DSA:2.60.120.1440 100 235 2.0E-6 T 13-10-2018 Astex_1182 6490c8b48aabf04f199520518ddbd294 284 Pfam PF04378 Ribosomal RNA large subunit methyltransferase D, RlmJ 33 280 8.3E-50 T 13-10-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 Astex_1182 6490c8b48aabf04f199520518ddbd294 284 Hamap MF_00934 Ribosomal RNA large subunit methyltransferase J [rlmJ]. 1 273 31.458 T 13-10-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 Astex_1182 6490c8b48aabf04f199520518ddbd294 284 SUPERFAMILY SSF53335 8 281 1.88E-55 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Astex_1182 6490c8b48aabf04f199520518ddbd294 284 Gene3D G3DSA:3.40.50.150 1 283 4.6E-68 T 13-10-2018 Astex_2949 754ede727de40c1619b56942765af8e0 333 PIRSF PIRSF001415 3 333 9.4E-140 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 Astex_2949 754ede727de40c1619b56942765af8e0 333 SMART SM01004 10 331 1.2E-213 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 Astex_2949 754ede727de40c1619b56942765af8e0 333 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 305 324 3.4E-58 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 Astex_2949 754ede727de40c1619b56942765af8e0 333 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 198 217 3.4E-58 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 Astex_2949 754ede727de40c1619b56942765af8e0 333 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 130 144 3.4E-58 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 Astex_2949 754ede727de40c1619b56942765af8e0 333 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 275 290 3.4E-58 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 Astex_2949 754ede727de40c1619b56942765af8e0 333 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 160 179 3.4E-58 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 Astex_2949 754ede727de40c1619b56942765af8e0 333 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 250 266 3.4E-58 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 Astex_2949 754ede727de40c1619b56942765af8e0 333 Gene3D G3DSA:3.20.20.70 8 333 1.8E-134 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_2949 754ede727de40c1619b56942765af8e0 333 Pfam PF00490 Delta-aminolevulinic acid dehydratase 13 329 2.0E-133 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 Astex_2949 754ede727de40c1619b56942765af8e0 333 SUPERFAMILY SSF51569 8 332 7.94E-134 T 13-10-2018 Astex_2949 754ede727de40c1619b56942765af8e0 333 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 250 262 - T 13-10-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 Astex_1185 7584a8b6f23f27b89bc75ccd84d89959 105 SUPERFAMILY SSF117782 1 104 2.49E-37 T 13-10-2018 IPR035439 UPF0145 domain superfamily Astex_1185 7584a8b6f23f27b89bc75ccd84d89959 105 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 1 104 25.426 T 13-10-2018 IPR002765 Uncharacterised protein family UPF0145 Astex_1185 7584a8b6f23f27b89bc75ccd84d89959 105 Gene3D G3DSA:3.30.110.70 1 105 1.6E-43 T 13-10-2018 Astex_1185 7584a8b6f23f27b89bc75ccd84d89959 105 Pfam PF01906 Putative heavy-metal-binding 1 103 8.3E-41 T 13-10-2018 IPR002765 Uncharacterised protein family UPF0145 Astex_3063 049640caf0be36f20a3a25a1d452c91e 434 PRINTS PR00149 Fumarate lyase superfamily signature 136 154 3.0E-24 T 13-10-2018 IPR000362 Fumarate lyase family Astex_3063 049640caf0be36f20a3a25a1d452c91e 434 PRINTS PR00149 Fumarate lyase superfamily signature 219 246 3.0E-24 T 13-10-2018 IPR000362 Fumarate lyase family Astex_3063 049640caf0be36f20a3a25a1d452c91e 434 PRINTS PR00149 Fumarate lyase superfamily signature 264 280 3.0E-24 T 13-10-2018 IPR000362 Fumarate lyase family Astex_3063 049640caf0be36f20a3a25a1d452c91e 434 PRINTS PR00149 Fumarate lyase superfamily signature 91 109 3.0E-24 T 13-10-2018 IPR000362 Fumarate lyase family Astex_3063 049640caf0be36f20a3a25a1d452c91e 434 Gene3D G3DSA:1.10.40.30 352 431 7.9E-29 T 13-10-2018 Astex_3063 049640caf0be36f20a3a25a1d452c91e 434 Pfam PF10397 Adenylosuccinate lyase C-terminus 353 431 6.2E-26 T 13-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Astex_3063 049640caf0be36f20a3a25a1d452c91e 434 SMART SM00998 352 432 2.1E-37 T 13-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Astex_3063 049640caf0be36f20a3a25a1d452c91e 434 Pfam PF00206 Lyase 26 287 5.8E-48 T 13-10-2018 IPR022761 Fumarate lyase, N-terminal Astex_3063 049640caf0be36f20a3a25a1d452c91e 434 ProSitePatterns PS00163 Fumarate lyases signature. 264 273 - T 13-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 Astex_3063 049640caf0be36f20a3a25a1d452c91e 434 SUPERFAMILY SSF48557 3 432 1.73E-124 T 13-10-2018 IPR008948 L-Aspartase-like GO:0003824 Astex_3063 049640caf0be36f20a3a25a1d452c91e 434 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 1 432 5.4E-147 T 13-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 Astex_3063 049640caf0be36f20a3a25a1d452c91e 434 Gene3D G3DSA:1.10.275.10 1 95 2.2E-27 T 13-10-2018 IPR024083 Fumarase/histidase, N-terminal Astex_3063 049640caf0be36f20a3a25a1d452c91e 434 PRINTS PR00145 Argininosuccinate lyase family signature 131 151 4.0E-7 T 13-10-2018 Astex_3063 049640caf0be36f20a3a25a1d452c91e 434 PRINTS PR00145 Argininosuccinate lyase family signature 264 280 4.0E-7 T 13-10-2018 Astex_3063 049640caf0be36f20a3a25a1d452c91e 434 PRINTS PR00145 Argininosuccinate lyase family signature 90 112 4.0E-7 T 13-10-2018 Astex_3063 049640caf0be36f20a3a25a1d452c91e 434 PRINTS PR00145 Argininosuccinate lyase family signature 219 243 4.0E-7 T 13-10-2018 Astex_3063 049640caf0be36f20a3a25a1d452c91e 434 Gene3D G3DSA:1.20.200.10 96 351 4.2E-87 T 13-10-2018 Astex_2536 4c4a453689511d9184aca3e871e927e7 108 Pfam PF01521 Iron-sulphur cluster biosynthesis 4 103 8.5E-19 T 13-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 Astex_2536 4c4a453689511d9184aca3e871e927e7 108 SUPERFAMILY SSF89360 3 97 4.12E-28 T 13-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 Astex_2536 4c4a453689511d9184aca3e871e927e7 108 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 4 107 2.9E-33 T 13-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 Astex_2536 4c4a453689511d9184aca3e871e927e7 108 Gene3D G3DSA:2.60.300.12 3 108 3.9E-34 T 13-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 Astex_2536 4c4a453689511d9184aca3e871e927e7 108 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 89 106 - T 13-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 Astex_1408 7c16e38dc358162e522cdb0c684c68e4 212 Gene3D G3DSA:1.10.10.10 115 205 4.3E-20 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1408 7c16e38dc358162e522cdb0c684c68e4 212 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 47 201 3.1E-25 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 Astex_1408 7c16e38dc358162e522cdb0c684c68e4 212 Pfam PF04542 Sigma-70 region 2 51 119 5.4E-18 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 Astex_1408 7c16e38dc358162e522cdb0c684c68e4 212 SUPERFAMILY SSF88946 34 137 1.47E-24 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 Astex_1408 7c16e38dc358162e522cdb0c684c68e4 212 Pfam PF04545 Sigma-70, region 4 152 201 1.8E-14 T 13-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 Astex_1408 7c16e38dc358162e522cdb0c684c68e4 212 Gene3D G3DSA:1.10.1740.10 32 114 6.6E-23 T 13-10-2018 Astex_1408 7c16e38dc358162e522cdb0c684c68e4 212 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 73 105 - T 13-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Astex_1408 7c16e38dc358162e522cdb0c684c68e4 212 SUPERFAMILY SSF88659 143 203 1.29E-14 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Astex_3270 532dbe2d3c7df102b0ae252f39750e8e 1038 SUPERFAMILY SSF82693 136 331 1.18E-25 T 13-10-2018 Astex_3270 532dbe2d3c7df102b0ae252f39750e8e 1038 Gene3D G3DSA:3.30.2090.10 719 807 0.0 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Astex_3270 532dbe2d3c7df102b0ae252f39750e8e 1038 Gene3D G3DSA:3.30.70.1430 39 815 0.0 T 13-10-2018 Astex_3270 532dbe2d3c7df102b0ae252f39750e8e 1038 SUPERFAMILY SSF82693 39 134 1.1E-26 T 13-10-2018 Astex_3270 532dbe2d3c7df102b0ae252f39750e8e 1038 Gene3D G3DSA:3.30.70.1440 667 863 0.0 T 13-10-2018 Astex_3270 532dbe2d3c7df102b0ae252f39750e8e 1038 Gene3D G3DSA:1.20.1640.10 515 1020 0.0 T 13-10-2018 Astex_3270 532dbe2d3c7df102b0ae252f39750e8e 1038 Pfam PF00873 AcrB/AcrD/AcrF family 3 1023 0.0 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3270 532dbe2d3c7df102b0ae252f39750e8e 1038 Gene3D G3DSA:3.30.70.1320 134 333 0.0 T 13-10-2018 Astex_3270 532dbe2d3c7df102b0ae252f39750e8e 1038 Gene3D G3DSA:3.30.2090.10 180 276 0.0 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Astex_3270 532dbe2d3c7df102b0ae252f39750e8e 1038 SUPERFAMILY SSF82693 567 667 2.09E-19 T 13-10-2018 Astex_3270 532dbe2d3c7df102b0ae252f39750e8e 1038 SUPERFAMILY SSF82693 670 854 6.02E-22 T 13-10-2018 Astex_3270 532dbe2d3c7df102b0ae252f39750e8e 1038 PRINTS PR00702 Acriflavin resistance protein family signature 554 571 2.4E-102 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3270 532dbe2d3c7df102b0ae252f39750e8e 1038 PRINTS PR00702 Acriflavin resistance protein family signature 392 416 2.4E-102 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3270 532dbe2d3c7df102b0ae252f39750e8e 1038 PRINTS PR00702 Acriflavin resistance protein family signature 337 360 2.4E-102 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3270 532dbe2d3c7df102b0ae252f39750e8e 1038 PRINTS PR00702 Acriflavin resistance protein family signature 446 469 2.4E-102 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3270 532dbe2d3c7df102b0ae252f39750e8e 1038 PRINTS PR00702 Acriflavin resistance protein family signature 37 55 2.4E-102 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3270 532dbe2d3c7df102b0ae252f39750e8e 1038 PRINTS PR00702 Acriflavin resistance protein family signature 617 631 2.4E-102 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3270 532dbe2d3c7df102b0ae252f39750e8e 1038 PRINTS PR00702 Acriflavin resistance protein family signature 9 33 2.4E-102 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3270 532dbe2d3c7df102b0ae252f39750e8e 1038 PRINTS PR00702 Acriflavin resistance protein family signature 364 385 2.4E-102 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3270 532dbe2d3c7df102b0ae252f39750e8e 1038 PRINTS PR00702 Acriflavin resistance protein family signature 471 494 2.4E-102 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3270 532dbe2d3c7df102b0ae252f39750e8e 1038 Gene3D G3DSA:3.30.70.1430 569 666 0.0 T 13-10-2018 Astex_3270 532dbe2d3c7df102b0ae252f39750e8e 1038 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 2 1034 0.0 T 13-10-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0006855|GO:0015562|GO:0016021 Astex_3270 532dbe2d3c7df102b0ae252f39750e8e 1038 Gene3D G3DSA:1.20.1640.10 9 514 0.0 T 13-10-2018 Astex_3270 532dbe2d3c7df102b0ae252f39750e8e 1038 SUPERFAMILY SSF82866 297 498 2.62E-50 T 13-10-2018 Astex_3270 532dbe2d3c7df102b0ae252f39750e8e 1038 SUPERFAMILY SSF82714 720 806 4.58E-22 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Astex_3270 532dbe2d3c7df102b0ae252f39750e8e 1038 SUPERFAMILY SSF82866 830 1023 6.41E-42 T 13-10-2018 Astex_3270 532dbe2d3c7df102b0ae252f39750e8e 1038 SUPERFAMILY SSF82714 183 273 7.46E-22 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Astex_0951 21565b8161e746c47182aedc001eafe3 251 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 13-10-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0951 21565b8161e746c47182aedc001eafe3 251 SMART SM00322 60 125 4.0E-5 T 13-10-2018 IPR004087 K Homology domain GO:0003676 Astex_0951 21565b8161e746c47182aedc001eafe3 251 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 209 5.5E-95 T 13-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 Astex_0951 21565b8161e746c47182aedc001eafe3 251 Pfam PF07650 KH domain 38 110 3.8E-20 T 13-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0951 21565b8161e746c47182aedc001eafe3 251 Gene3D G3DSA:3.30.1140.32 108 208 5.6E-42 T 13-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0951 21565b8161e746c47182aedc001eafe3 251 SUPERFAMILY SSF54814 2 106 2.62E-37 T 13-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 Astex_0951 21565b8161e746c47182aedc001eafe3 251 SUPERFAMILY SSF54821 108 206 5.1E-39 T 13-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0951 21565b8161e746c47182aedc001eafe3 251 Pfam PF00189 Ribosomal protein S3, C-terminal domain 120 202 1.1E-39 T 13-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0951 21565b8161e746c47182aedc001eafe3 251 Gene3D G3DSA:3.30.300.20 17 107 3.5E-29 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta Astex_0951 21565b8161e746c47182aedc001eafe3 251 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 39.346 T 13-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 Astex_0788 db05c4cc5f078c45595587b1c2347f31 274 PIRSF PIRSF006157 2 274 6.4E-87 T 13-10-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 Astex_0788 db05c4cc5f078c45595587b1c2347f31 274 SUPERFAMILY SSF53213 7 274 1.44E-83 T 13-10-2018 Astex_0788 db05c4cc5f078c45595587b1c2347f31 274 Gene3D G3DSA:3.40.830.10 1 274 2.1E-87 T 13-10-2018 Astex_0788 db05c4cc5f078c45595587b1c2347f31 274 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 28 251 7.7E-38 T 13-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 Astex_3392 6361a49044906546267c5ee6fba42359 182 SMART SM00554 71 182 6.1E-23 T 13-10-2018 IPR000782 FAS1 domain Astex_3392 6361a49044906546267c5ee6fba42359 182 Gene3D G3DSA:2.30.180.10 35 182 4.4E-44 T 13-10-2018 IPR036378 FAS1 domain superfamily Astex_3392 6361a49044906546267c5ee6fba42359 182 Pfam PF02469 Fasciclin domain 46 181 2.4E-29 T 13-10-2018 IPR000782 FAS1 domain Astex_3392 6361a49044906546267c5ee6fba42359 182 SUPERFAMILY SSF82153 36 181 6.54E-40 T 13-10-2018 IPR036378 FAS1 domain superfamily Astex_0949 1558d213d0c9c4e5e87ddc3abe3ddd2e 92 SUPERFAMILY SSF54570 3 84 1.57E-33 T 13-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0949 1558d213d0c9c4e5e87ddc3abe3ddd2e 92 Pfam PF00203 Ribosomal protein S19 3 83 3.1E-35 T 13-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0949 1558d213d0c9c4e5e87ddc3abe3ddd2e 92 PIRSF PIRSF002144 1 92 4.4E-32 T 13-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0949 1558d213d0c9c4e5e87ddc3abe3ddd2e 92 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 1.6E-20 T 13-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0949 1558d213d0c9c4e5e87ddc3abe3ddd2e 92 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 1.6E-20 T 13-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0949 1558d213d0c9c4e5e87ddc3abe3ddd2e 92 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 1.6E-20 T 13-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0949 1558d213d0c9c4e5e87ddc3abe3ddd2e 92 Gene3D G3DSA:3.30.860.10 1 92 1.8E-38 T 13-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0949 1558d213d0c9c4e5e87ddc3abe3ddd2e 92 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 91 1.5E-41 T 13-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 Astex_0949 1558d213d0c9c4e5e87ddc3abe3ddd2e 92 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 13-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0949 1558d213d0c9c4e5e87ddc3abe3ddd2e 92 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 24.203 T 13-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_3614 79aa5cde38f2bfa7229a3077c5cab0ce 808 Gene3D G3DSA:2.60.120.260 9 223 4.5E-38 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_3614 79aa5cde38f2bfa7229a3077c5cab0ce 808 Pfam PF00703 Glycosyl hydrolases family 2 232 332 1.3E-14 T 13-10-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_3614 79aa5cde38f2bfa7229a3077c5cab0ce 808 Gene3D G3DSA:2.60.40.10 700 808 6.7E-34 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_3614 79aa5cde38f2bfa7229a3077c5cab0ce 808 Gene3D G3DSA:2.60.40.10 225 332 1.5E-20 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_3614 79aa5cde38f2bfa7229a3077c5cab0ce 808 SUPERFAMILY SSF51445 338 620 1.08E-70 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_3614 79aa5cde38f2bfa7229a3077c5cab0ce 808 SUPERFAMILY SSF49785 19 224 1.98E-35 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_3614 79aa5cde38f2bfa7229a3077c5cab0ce 808 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 340 417 3.7E-18 T 13-10-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 Astex_3614 79aa5cde38f2bfa7229a3077c5cab0ce 808 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 423 585 4.4E-13 T 13-10-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 Astex_3614 79aa5cde38f2bfa7229a3077c5cab0ce 808 Gene3D G3DSA:3.20.20.80 334 619 2.5E-98 T 13-10-2018 Astex_3614 79aa5cde38f2bfa7229a3077c5cab0ce 808 SUPERFAMILY SSF49303 238 332 6.33E-16 T 13-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily Astex_3614 79aa5cde38f2bfa7229a3077c5cab0ce 808 Gene3D G3DSA:2.60.40.10 621 697 1.2E-28 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_3614 79aa5cde38f2bfa7229a3077c5cab0ce 808 ProSitePatterns PS00608 Glycosyl hydrolases family 2 acid/base catalyst. 433 447 - T 13-10-2018 IPR023232 Glycoside hydrolase, family 2, active site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_3614 79aa5cde38f2bfa7229a3077c5cab0ce 808 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 82 222 8.6E-10 T 13-10-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_3614 79aa5cde38f2bfa7229a3077c5cab0ce 808 PRINTS PR00132 Glycosyl hydrolase family 2 signature 344 358 3.3E-8 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_3614 79aa5cde38f2bfa7229a3077c5cab0ce 808 PRINTS PR00132 Glycosyl hydrolase family 2 signature 433 448 3.3E-8 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_3614 79aa5cde38f2bfa7229a3077c5cab0ce 808 Pfam PF16355 Domain of unknown function (DUF4982) 632 690 2.0E-22 T 13-10-2018 IPR032311 Domain of unknown function DUF4982 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_1877 bb3bf175cbeca22c6c5c72ee722eaa41 392 Pfam PF12536 Patatin phospholipase 271 375 2.1E-33 T 13-10-2018 IPR021095 Protein of unknown function DUF3734 Astex_1877 bb3bf175cbeca22c6c5c72ee722eaa41 392 Pfam PF01734 Patatin-like phospholipase 26 231 2.3E-27 T 13-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 Astex_1877 bb3bf175cbeca22c6c5c72ee722eaa41 392 SUPERFAMILY SSF52151 24 369 3.31E-50 T 13-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase Astex_1877 bb3bf175cbeca22c6c5c72ee722eaa41 392 Gene3D G3DSA:3.40.1090.10 11 118 1.2E-15 T 13-10-2018 Astex_1877 bb3bf175cbeca22c6c5c72ee722eaa41 392 Gene3D G3DSA:3.40.1090.10 139 298 1.8E-18 T 13-10-2018 Astex_3138 50cca81c84e0600d945514b6a4ec1fad 480 Gene3D G3DSA:1.20.1600.10 38 444 3.1E-92 T 13-10-2018 Astex_3138 50cca81c84e0600d945514b6a4ec1fad 480 SUPERFAMILY SSF56954 19 429 1.83E-88 T 13-10-2018 Astex_3138 50cca81c84e0600d945514b6a4ec1fad 480 Pfam PF02321 Outer membrane efflux protein 242 428 9.8E-28 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Astex_3138 50cca81c84e0600d945514b6a4ec1fad 480 Pfam PF02321 Outer membrane efflux protein 41 221 7.6E-30 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Astex_3138 50cca81c84e0600d945514b6a4ec1fad 480 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 37 443 7.9E-91 T 13-10-2018 IPR010130 Type I secretion outer membrane protein, TolC GO:0015562|GO:0019867|GO:0055085 Astex_0388 13aea90b99310e14fb9b2c93b5704ed2 188 Gene3D G3DSA:3.40.980.10 16 185 1.7E-50 T 13-10-2018 IPR036425 MoaB/Mog-like domain superfamily Astex_0388 13aea90b99310e14fb9b2c93b5704ed2 188 PIRSF PIRSF006443 14 180 7.0E-64 T 13-10-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 Astex_0388 13aea90b99310e14fb9b2c93b5704ed2 188 TIGRFAM TIGR02667 moaB_proteo: molybdenum cofactor biosynthesis protein B 22 183 3.8E-77 T 13-10-2018 IPR013484 Molybdenum cofactor biosynthesis protein B, proteobacteria GO:0006777 Astex_0388 13aea90b99310e14fb9b2c93b5704ed2 188 SMART SM00852 28 172 2.8E-29 T 13-10-2018 IPR001453 MoaB/Mog domain Astex_0388 13aea90b99310e14fb9b2c93b5704ed2 188 SUPERFAMILY SSF53218 20 184 3.66E-47 T 13-10-2018 IPR036425 MoaB/Mog-like domain superfamily Astex_0388 13aea90b99310e14fb9b2c93b5704ed2 188 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 86 99 - T 13-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 Astex_0388 13aea90b99310e14fb9b2c93b5704ed2 188 Pfam PF00994 Probable molybdopterin binding domain 28 167 4.5E-36 T 13-10-2018 IPR001453 MoaB/Mog domain Astex_0388 13aea90b99310e14fb9b2c93b5704ed2 188 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 26 165 1.1E-34 T 13-10-2018 IPR001453 MoaB/Mog domain Astex_0253 a8a417b7bc7d3450a4a9e0836af3303b 118 SUPERFAMILY SSF48295 10 58 2.88E-9 T 13-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 Astex_0253 a8a417b7bc7d3450a4a9e0836af3303b 118 Pfam PF01527 Transposase 13 61 3.9E-13 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 Astex_3232 a8a417b7bc7d3450a4a9e0836af3303b 118 SUPERFAMILY SSF48295 10 58 2.88E-9 T 13-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 Astex_3232 a8a417b7bc7d3450a4a9e0836af3303b 118 Pfam PF01527 Transposase 13 61 3.9E-13 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 Astex_0872 84a16f04a21334234ff98e4847d4fc2b 240 SUPERFAMILY SSF74653 124 238 1.7E-20 T 13-10-2018 Astex_0872 84a16f04a21334234ff98e4847d4fc2b 240 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 162 236 1.2E-12 T 13-10-2018 IPR037682 TonB, C-terminal GO:0055085 Astex_0872 84a16f04a21334234ff98e4847d4fc2b 240 Gene3D G3DSA:3.30.1150.10 109 239 1.9E-28 T 13-10-2018 Astex_0872 84a16f04a21334234ff98e4847d4fc2b 240 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 162 223 6.7E-17 T 13-10-2018 IPR006260 TonB/TolA, C-terminal Astex_0273 2760778da74b04de5cd0cc15288a7ba3 232 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 60 71 1.8E-5 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0273 2760778da74b04de5cd0cc15288a7ba3 232 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 111 119 1.8E-5 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0273 2760778da74b04de5cd0cc15288a7ba3 232 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 150 1.8E-5 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0273 2760778da74b04de5cd0cc15288a7ba3 232 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 8 224 2.4E-50 T 13-10-2018 Astex_0273 2760778da74b04de5cd0cc15288a7ba3 232 Gene3D G3DSA:3.40.50.720 3 230 8.6E-55 T 13-10-2018 Astex_0273 2760778da74b04de5cd0cc15288a7ba3 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 105 121 5.2E-31 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0273 2760778da74b04de5cd0cc15288a7ba3 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 207 5.2E-31 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0273 2760778da74b04de5cd0cc15288a7ba3 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 150 5.2E-31 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0273 2760778da74b04de5cd0cc15288a7ba3 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 5.2E-31 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0273 2760778da74b04de5cd0cc15288a7ba3 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 60 71 5.2E-31 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0273 2760778da74b04de5cd0cc15288a7ba3 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 169 5.2E-31 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0273 2760778da74b04de5cd0cc15288a7ba3 232 SUPERFAMILY SSF51735 4 225 1.1E-58 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_2614 78ac8de615757ae926d791afa13dfe3c 481 Gene3D G3DSA:3.30.2290.10 9 236 2.2E-12 T 13-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal Astex_2614 78ac8de615757ae926d791afa13dfe3c 481 PIRSF PIRSF004919 20 480 1.1E-131 T 13-10-2018 IPR025502 TldD Astex_2614 78ac8de615757ae926d791afa13dfe3c 481 SUPERFAMILY SSF111283 24 479 3.27E-122 T 13-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 Astex_2614 78ac8de615757ae926d791afa13dfe3c 481 Pfam PF01523 Putative modulator of DNA gyrase 39 331 5.4E-62 T 13-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 Astex_1035 f3d7f895277a03aa10ad07e7cb5df599 250 Gene3D G3DSA:3.40.50.300 2 235 1.6E-61 T 13-10-2018 Astex_1035 f3d7f895277a03aa10ad07e7cb5df599 250 SUPERFAMILY SSF52540 12 225 2.72E-58 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1035 f3d7f895277a03aa10ad07e7cb5df599 250 Pfam PF00005 ABC transporter 28 171 1.7E-29 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_1035 f3d7f895277a03aa10ad07e7cb5df599 250 SMART SM00382 37 219 2.2E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_2406 2993fa08dffe10475535e28408d695c1 392 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 5.8E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_2406 2993fa08dffe10475535e28408d695c1 392 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 5.8E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_2406 2993fa08dffe10475535e28408d695c1 392 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 5.8E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_2406 2993fa08dffe10475535e28408d695c1 392 SUPERFAMILY SSF53850 186 389 2.17E-36 T 13-10-2018 Astex_2406 2993fa08dffe10475535e28408d695c1 392 SUPERFAMILY SSF46785 2 82 8.76E-18 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_2406 2993fa08dffe10475535e28408d695c1 392 Gene3D G3DSA:3.40.190.10 262 364 3.1E-47 T 13-10-2018 Astex_2406 2993fa08dffe10475535e28408d695c1 392 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 3.8E-20 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_2406 2993fa08dffe10475535e28408d695c1 392 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 101 158 1.2E-9 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_2406 2993fa08dffe10475535e28408d695c1 392 Gene3D G3DSA:3.40.190.10 189 378 3.1E-47 T 13-10-2018 Astex_2406 2993fa08dffe10475535e28408d695c1 392 Gene3D G3DSA:1.10.10.10 98 185 3.5E-12 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_2406 2993fa08dffe10475535e28408d695c1 392 SUPERFAMILY SSF46785 100 207 2.73E-13 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_2406 2993fa08dffe10475535e28408d695c1 392 Pfam PF03466 LysR substrate binding domain 185 390 1.0E-32 T 13-10-2018 IPR005119 LysR, substrate-binding Astex_2406 2993fa08dffe10475535e28408d695c1 392 Gene3D G3DSA:1.10.10.10 1 89 5.3E-21 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_3216 814e21fa3c12db1bf1bb481989fb09ef 231 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 68 1.3E-10 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Astex_3216 814e21fa3c12db1bf1bb481989fb09ef 231 Gene3D G3DSA:1.20.120.530 95 226 8.8E-19 T 13-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal Astex_3216 814e21fa3c12db1bf1bb481989fb09ef 231 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 3.3E-8 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Astex_3216 814e21fa3c12db1bf1bb481989fb09ef 231 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 3.3E-8 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Astex_3216 814e21fa3c12db1bf1bb481989fb09ef 231 SMART SM00895 101 219 5.5E-16 T 13-10-2018 IPR011711 GntR, C-terminal Astex_3216 814e21fa3c12db1bf1bb481989fb09ef 231 SUPERFAMILY SSF46785 9 69 8.41E-11 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_3216 814e21fa3c12db1bf1bb481989fb09ef 231 SUPERFAMILY SSF48008 100 225 1.41E-16 T 13-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal Astex_3216 814e21fa3c12db1bf1bb481989fb09ef 231 Pfam PF07729 FCD domain 101 218 4.3E-16 T 13-10-2018 IPR011711 GntR, C-terminal Astex_3216 814e21fa3c12db1bf1bb481989fb09ef 231 Gene3D G3DSA:1.10.10.10 8 73 9.7E-12 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_0463 b0e7f1b548d349bdbc80eefd3f485217 554 Gene3D G3DSA:3.40.630.10 19 92 1.2E-5 T 13-10-2018 Astex_0463 b0e7f1b548d349bdbc80eefd3f485217 554 Pfam PF02225 PA domain 130 213 1.6E-6 T 13-10-2018 IPR003137 PA domain Astex_0463 b0e7f1b548d349bdbc80eefd3f485217 554 Pfam PF04389 Peptidase family M28 300 517 3.3E-42 T 13-10-2018 IPR007484 Peptidase M28 Astex_0463 b0e7f1b548d349bdbc80eefd3f485217 554 Gene3D G3DSA:3.40.630.10 252 528 1.7E-47 T 13-10-2018 Astex_0463 b0e7f1b548d349bdbc80eefd3f485217 554 SUPERFAMILY SSF53187 25 531 4.72E-62 T 13-10-2018 Astex_0463 b0e7f1b548d349bdbc80eefd3f485217 554 SUPERFAMILY SSF52025 128 227 4.19E-9 T 13-10-2018 Astex_3095 2297d71b3af15da22634293f5a13ae4a 202 Gene3D G3DSA:1.10.260.40 6 78 4.4E-10 T 13-10-2018 Astex_3095 2297d71b3af15da22634293f5a13ae4a 202 SMART SM00530 10 68 1.9E-6 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Astex_3095 2297d71b3af15da22634293f5a13ae4a 202 Pfam PF13560 Helix-turn-helix domain 8 66 2.3E-10 T 13-10-2018 Astex_3095 2297d71b3af15da22634293f5a13ae4a 202 SUPERFAMILY SSF47413 6 68 6.97E-9 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Astex_1581 8938fcda2094f49d1621ecce3c6b04fc 453 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 344 445 1.2E-16 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_1581 8938fcda2094f49d1621ecce3c6b04fc 453 SUPERFAMILY SSF55874 291 452 5.11E-26 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_1581 8938fcda2094f49d1621ecce3c6b04fc 453 SUPERFAMILY SSF47384 227 299 9.02E-12 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Astex_1581 8938fcda2094f49d1621ecce3c6b04fc 453 SMART SM00304 190 242 3.4E-4 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Astex_1581 8938fcda2094f49d1621ecce3c6b04fc 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 432 7.2E-9 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1581 8938fcda2094f49d1621ecce3c6b04fc 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 379 393 7.2E-9 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1581 8938fcda2094f49d1621ecce3c6b04fc 453 Gene3D G3DSA:3.30.565.10 305 452 1.4E-25 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_1581 8938fcda2094f49d1621ecce3c6b04fc 453 Gene3D G3DSA:1.10.287.130 194 302 4.6E-18 T 13-10-2018 Astex_1581 8938fcda2094f49d1621ecce3c6b04fc 453 SMART SM00388 243 301 9.6E-7 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_1581 8938fcda2094f49d1621ecce3c6b04fc 453 SMART SM00387 340 453 8.0E-21 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_1296 fb5f72eba93665c0c12bca13be256884 437 SUPERFAMILY SSF52218 43 183 2.3E-36 T 13-10-2018 IPR029039 Flavoprotein-like superfamily Astex_1296 fb5f72eba93665c0c12bca13be256884 437 Pfam PF00258 Flavodoxin 46 172 3.8E-25 T 13-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 Astex_1296 fb5f72eba93665c0c12bca13be256884 437 SUPERFAMILY SSF63380 193 299 2.7E-12 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel Astex_1296 fb5f72eba93665c0c12bca13be256884 437 Gene3D G3DSA:3.40.50.80 299 437 1.9E-25 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain Astex_1296 fb5f72eba93665c0c12bca13be256884 437 PRINTS PR00369 Flavodoxin signature 45 58 8.6E-5 T 13-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 Astex_1296 fb5f72eba93665c0c12bca13be256884 437 PRINTS PR00369 Flavodoxin signature 93 104 8.6E-5 T 13-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 Astex_1296 fb5f72eba93665c0c12bca13be256884 437 PRINTS PR00369 Flavodoxin signature 124 134 8.6E-5 T 13-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 Astex_1296 fb5f72eba93665c0c12bca13be256884 437 Gene3D G3DSA:3.40.50.360 42 185 2.5E-37 T 13-10-2018 IPR029039 Flavoprotein-like superfamily Astex_1296 fb5f72eba93665c0c12bca13be256884 437 Pfam PF00175 Oxidoreductase NAD-binding domain 307 410 3.1E-5 T 13-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 Astex_1296 fb5f72eba93665c0c12bca13be256884 437 Gene3D G3DSA:2.40.30.10 186 292 3.9E-7 T 13-10-2018 Astex_1296 fb5f72eba93665c0c12bca13be256884 437 SUPERFAMILY SSF52343 296 437 2.1E-27 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain Astex_1281 40c420d2ebd021974ae61d20117ae09c 385 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 51 172 2.3E-27 T 13-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 Astex_1281 40c420d2ebd021974ae61d20117ae09c 385 SUPERFAMILY SSF51735 40 201 8.36E-50 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_1281 40c420d2ebd021974ae61d20117ae09c 385 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 188 291 2.4E-6 T 13-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 Astex_1281 40c420d2ebd021974ae61d20117ae09c 385 PRINTS PR01775 Bacterial glucose-fructose oxidoreductase signature 162 176 3.3E-30 T 13-10-2018 IPR008354 Glucose-fructose oxidoreductase, bacterial MetaCyc: PWY-5530 Astex_1281 40c420d2ebd021974ae61d20117ae09c 385 PRINTS PR01775 Bacterial glucose-fructose oxidoreductase signature 48 61 3.3E-30 T 13-10-2018 IPR008354 Glucose-fructose oxidoreductase, bacterial MetaCyc: PWY-5530 Astex_1281 40c420d2ebd021974ae61d20117ae09c 385 PRINTS PR01775 Bacterial glucose-fructose oxidoreductase signature 100 116 3.3E-30 T 13-10-2018 IPR008354 Glucose-fructose oxidoreductase, bacterial MetaCyc: PWY-5530 Astex_1281 40c420d2ebd021974ae61d20117ae09c 385 PRINTS PR01775 Bacterial glucose-fructose oxidoreductase signature 298 313 3.3E-30 T 13-10-2018 IPR008354 Glucose-fructose oxidoreductase, bacterial MetaCyc: PWY-5530 Astex_1281 40c420d2ebd021974ae61d20117ae09c 385 PRINTS PR01775 Bacterial glucose-fructose oxidoreductase signature 351 367 3.3E-30 T 13-10-2018 IPR008354 Glucose-fructose oxidoreductase, bacterial MetaCyc: PWY-5530 Astex_1281 40c420d2ebd021974ae61d20117ae09c 385 PRINTS PR01775 Bacterial glucose-fructose oxidoreductase signature 255 271 3.3E-30 T 13-10-2018 IPR008354 Glucose-fructose oxidoreductase, bacterial MetaCyc: PWY-5530 Astex_1281 40c420d2ebd021974ae61d20117ae09c 385 Gene3D G3DSA:3.40.50.720 53 358 2.2E-95 T 13-10-2018 Astex_1281 40c420d2ebd021974ae61d20117ae09c 385 Gene3D G3DSA:3.30.360.10 177 379 2.2E-95 T 13-10-2018 Astex_1281 40c420d2ebd021974ae61d20117ae09c 385 SUPERFAMILY SSF55347 178 321 1.8E-29 T 13-10-2018 Astex_0770 4a563c9154811d3aa911f7ff6020c2f2 212 Hamap MF_00942 Endonuclease III [nth]. 1 212 36.201 T 13-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 Astex_0770 4a563c9154811d3aa911f7ff6020c2f2 212 Gene3D G3DSA:1.10.340.30 22 133 2.2E-71 T 13-10-2018 Astex_0770 4a563c9154811d3aa911f7ff6020c2f2 212 SMART SM00478 39 188 4.6E-52 T 13-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 Astex_0770 4a563c9154811d3aa911f7ff6020c2f2 212 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 35 171 6.0E-22 T 13-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 Astex_0770 4a563c9154811d3aa911f7ff6020c2f2 212 Pfam PF00633 Helix-hairpin-helix motif 100 127 1.6E-5 T 13-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 Astex_0770 4a563c9154811d3aa911f7ff6020c2f2 212 SUPERFAMILY SSF48150 5 208 3.14E-65 T 13-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 Astex_0770 4a563c9154811d3aa911f7ff6020c2f2 212 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 190 206 - T 13-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 Astex_0770 4a563c9154811d3aa911f7ff6020c2f2 212 PIRSF PIRSF001435 2 211 3.8E-49 T 13-10-2018 Astex_0770 4a563c9154811d3aa911f7ff6020c2f2 212 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 190 206 2.3E-5 T 13-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 Astex_0770 4a563c9154811d3aa911f7ff6020c2f2 212 Gene3D G3DSA:1.10.1670.10 12 206 2.2E-71 T 13-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 Astex_0770 4a563c9154811d3aa911f7ff6020c2f2 212 SMART SM00525 189 209 5.7E-4 T 13-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 Astex_0770 4a563c9154811d3aa911f7ff6020c2f2 212 TIGRFAM TIGR01083 nth: endonuclease III 7 197 3.1E-74 T 13-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 Astex_1147 d0c6b41da3a3fe61f705d0fa8fee002d 523 Gene3D G3DSA:3.40.710.10 25 382 4.2E-83 T 13-10-2018 Astex_1147 d0c6b41da3a3fe61f705d0fa8fee002d 523 Gene3D G3DSA:2.40.128.600 407 505 3.2E-7 T 13-10-2018 Astex_1147 d0c6b41da3a3fe61f705d0fa8fee002d 523 SUPERFAMILY SSF56601 33 383 9.32E-77 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like Astex_1147 d0c6b41da3a3fe61f705d0fa8fee002d 523 Pfam PF11954 Domain of unknown function (DUF3471) 415 522 2.9E-23 T 13-10-2018 IPR021860 Peptidase S12, Pab87-related, C-terminal Astex_1147 d0c6b41da3a3fe61f705d0fa8fee002d 523 Pfam PF00144 Beta-lactamase 34 384 1.1E-62 T 13-10-2018 IPR001466 Beta-lactamase-related Astex_0589 4f46f460a4f961cf1437c7ef9aeb587f 224 Pfam PF03963 Flagellar hook capping protein - N-terminal region 4 75 2.2E-19 T 13-10-2018 IPR005648 Flagellar hook capping protein Astex_0589 4f46f460a4f961cf1437c7ef9aeb587f 224 Pfam PF13861 FlgD Tudor-like domain 84 216 1.1E-6 T 13-10-2018 IPR025963 FlgD Tudor-like domain Astex_0589 4f46f460a4f961cf1437c7ef9aeb587f 224 Gene3D G3DSA:2.60.40.4070 100 186 1.2E-19 T 13-10-2018 Astex_0589 4f46f460a4f961cf1437c7ef9aeb587f 224 Pfam PF13860 FlgD Ig-like domain 102 176 2.4E-17 T 13-10-2018 IPR025965 FlgD Ig-like domain Astex_0589 4f46f460a4f961cf1437c7ef9aeb587f 224 Gene3D G3DSA:2.30.30.910 90 207 1.2E-19 T 13-10-2018 Astex_2463 d1c581f2efe44a3acdb371a1a2ed292c 291 PIRSF PIRSF000103 1 291 1.0E-75 T 13-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 Astex_2463 d1c581f2efe44a3acdb371a1a2ed292c 291 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 165 284 1.2E-24 T 13-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 Astex_2463 d1c581f2efe44a3acdb371a1a2ed292c 291 Gene3D G3DSA:3.40.50.720 3 162 3.9E-46 T 13-10-2018 Astex_2463 d1c581f2efe44a3acdb371a1a2ed292c 291 Gene3D G3DSA:1.10.1040.10 163 290 1.3E-31 T 13-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 Astex_2463 d1c581f2efe44a3acdb371a1a2ed292c 291 SUPERFAMILY SSF48179 163 284 7.48E-29 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Astex_2463 d1c581f2efe44a3acdb371a1a2ed292c 291 SUPERFAMILY SSF51735 3 163 8.31E-39 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_2463 d1c581f2efe44a3acdb371a1a2ed292c 291 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 162 1.1E-36 T 13-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 Astex_2463 d1c581f2efe44a3acdb371a1a2ed292c 291 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 7 20 - T 13-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 Astex_2639 c3a8bf2ae045fcd8dc6840724c03b495 373 Gene3D G3DSA:3.20.20.105 1 372 3.6E-158 T 13-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 Astex_2639 c3a8bf2ae045fcd8dc6840724c03b495 373 Pfam PF01702 Queuine tRNA-ribosyltransferase 130 364 8.3E-81 T 13-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 Astex_2639 c3a8bf2ae045fcd8dc6840724c03b495 373 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 6 368 2.1E-138 T 13-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 Astex_2639 c3a8bf2ae045fcd8dc6840724c03b495 373 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 6 367 1.9E-143 T 13-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 Astex_2639 c3a8bf2ae045fcd8dc6840724c03b495 373 SUPERFAMILY SSF51713 2 368 9.94E-146 T 13-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 Astex_2639 c3a8bf2ae045fcd8dc6840724c03b495 373 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 4 367 53.286 T 13-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 Astex_0214 e81ccec1f46a3f95a91947f3372b02ea 458 Pfam PF06123 Inner membrane protein CreD 18 451 2.2E-129 T 13-10-2018 IPR010364 Uncharacterised protein family, inner membrane CreD Astex_0214 e81ccec1f46a3f95a91947f3372b02ea 458 PIRSF PIRSF004548 9 458 1.7E-111 T 13-10-2018 IPR010364 Uncharacterised protein family, inner membrane CreD Astex_0460 1126055dc117bee816b70a3905d82caf 155 SUPERFAMILY SSF54593 1 137 1.25E-32 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Astex_0460 1126055dc117bee816b70a3905d82caf 155 ProSitePatterns PS00934 Glyoxalase I signature 1. 5 26 - T 13-10-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 Astex_0460 1126055dc117bee816b70a3905d82caf 155 Gene3D G3DSA:3.10.180.10 1 141 7.5E-35 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Astex_0460 1126055dc117bee816b70a3905d82caf 155 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 133 2.7E-15 T 13-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Astex_0466 fce800df6bc5d2ff411bac25acbcd042 560 Pfam PF12729 Four helix bundle sensory module for signal transduction 4 176 1.2E-14 T 13-10-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain Astex_0466 fce800df6bc5d2ff411bac25acbcd042 560 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 321 350 1.4E-18 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_0466 fce800df6bc5d2ff411bac25acbcd042 560 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 398 425 1.4E-18 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_0466 fce800df6bc5d2ff411bac25acbcd042 560 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 427 456 1.4E-18 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_0466 fce800df6bc5d2ff411bac25acbcd042 560 Gene3D G3DSA:1.20.1480.50 171 264 5.5E-14 T 13-10-2018 Astex_0466 fce800df6bc5d2ff411bac25acbcd042 560 SMART SM00283 300 554 7.1E-41 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_0466 fce800df6bc5d2ff411bac25acbcd042 560 SUPERFAMILY SSF58104 240 553 5.49E-58 T 13-10-2018 Astex_0466 fce800df6bc5d2ff411bac25acbcd042 560 SMART SM00304 210 263 1.8E-7 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Astex_0466 fce800df6bc5d2ff411bac25acbcd042 560 Gene3D G3DSA:1.10.287.950 265 559 6.8E-50 T 13-10-2018 Astex_0466 fce800df6bc5d2ff411bac25acbcd042 560 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 363 520 6.1E-28 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_0472 4a1780ca79986e054046dc2c25fb29e7 355 Gene3D G3DSA:1.10.10.60 81 146 2.4E-22 T 13-10-2018 Astex_0472 4a1780ca79986e054046dc2c25fb29e7 355 Gene3D G3DSA:1.10.10.10 269 354 3.8E-32 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_0472 4a1780ca79986e054046dc2c25fb29e7 355 SMART SM00342 100 182 2.2E-17 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Astex_0472 4a1780ca79986e054046dc2c25fb29e7 355 SUPERFAMILY SSF53155 190 268 6.28E-21 T 13-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 Astex_0472 4a1780ca79986e054046dc2c25fb29e7 355 Pfam PF12833 Helix-turn-helix domain 106 183 3.9E-19 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Astex_0472 4a1780ca79986e054046dc2c25fb29e7 355 SUPERFAMILY SSF46767 270 350 4.32E-28 T 13-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 Astex_0472 4a1780ca79986e054046dc2c25fb29e7 355 Gene3D G3DSA:3.40.10.10 1 77 2.2E-30 T 13-10-2018 IPR035451 Ada-like domain superfamily Astex_0472 4a1780ca79986e054046dc2c25fb29e7 355 SUPERFAMILY SSF46689 85 133 7.92E-10 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Astex_0472 4a1780ca79986e054046dc2c25fb29e7 355 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 320 326 - T 13-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 Astex_0472 4a1780ca79986e054046dc2c25fb29e7 355 PIRSF PIRSF000409 1 355 1.4E-139 T 13-10-2018 IPR016221 Bifunctional regulatory protein Ada Astex_0472 4a1780ca79986e054046dc2c25fb29e7 355 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 270 349 4.0E-32 T 13-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 Astex_0472 4a1780ca79986e054046dc2c25fb29e7 355 Pfam PF02805 Metal binding domain of Ada 12 75 2.5E-29 T 13-10-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 Astex_0472 4a1780ca79986e054046dc2c25fb29e7 355 Gene3D G3DSA:3.30.160.70 176 268 8.9E-30 T 13-10-2018 Astex_0472 4a1780ca79986e054046dc2c25fb29e7 355 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 272 350 2.5E-29 T 13-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 Astex_0472 4a1780ca79986e054046dc2c25fb29e7 355 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 86 129 - T 13-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 Astex_0472 4a1780ca79986e054046dc2c25fb29e7 355 SUPERFAMILY SSF57884 2 91 2.62E-29 T 13-10-2018 IPR035451 Ada-like domain superfamily Astex_1167 096ec044b0e63e1dd508ffff9a6ef2c5 387 TIGRFAM TIGR02080 O_succ_thio_ly: O-succinylhomoserine (thiol)-lyase 12 385 1.6E-166 T 13-10-2018 IPR011821 O-succinylhomoserine (thiol)-lyase KEGG: 00270+2.5.1.48|KEGG: 00450+2.5.1.48|KEGG: 00920+2.5.1.48|MetaCyc: PWY-801 Astex_1167 096ec044b0e63e1dd508ffff9a6ef2c5 387 Gene3D G3DSA:3.40.640.10 8 251 1.2E-73 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Astex_1167 096ec044b0e63e1dd508ffff9a6ef2c5 387 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 13 384 5.6E-129 T 13-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 Astex_1167 096ec044b0e63e1dd508ffff9a6ef2c5 387 SUPERFAMILY SSF53383 12 385 8.97E-109 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Astex_1167 096ec044b0e63e1dd508ffff9a6ef2c5 387 Gene3D G3DSA:3.90.1150.10 253 387 6.5E-56 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Astex_1167 096ec044b0e63e1dd508ffff9a6ef2c5 387 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 194 208 - T 13-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 Astex_1167 096ec044b0e63e1dd508ffff9a6ef2c5 387 PIRSF PIRSF001434 1 387 4.7E-128 T 13-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 Astex_3309 36e5198440b6d179b45e728e8f170e92 513 PIRSF PIRSF011396 3 503 1.6E-187 T 13-10-2018 IPR033856 Flavin-dependent tryptophan halogenase Astex_3309 36e5198440b6d179b45e728e8f170e92 513 Pfam PF04820 Tryptophan halogenase 11 466 1.9E-185 T 13-10-2018 IPR006905 Flavin-dependent halogenase Astex_3309 36e5198440b6d179b45e728e8f170e92 513 SUPERFAMILY SSF51905 9 426 2.04E-33 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_3309 36e5198440b6d179b45e728e8f170e92 513 Gene3D G3DSA:3.50.50.60 4 503 1.2E-185 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_2775 b88499b8b95431fae9aef0bf121d9b0b 211 SUPERFAMILY SSF56935 18 198 4.12E-8 T 13-10-2018 Astex_2775 b88499b8b95431fae9aef0bf121d9b0b 211 Pfam PF09694 Bacterial protein of unknown function (Gcw_chp) 20 202 7.0E-30 T 13-10-2018 IPR010239 Conserved hypothetical protein CHP02001 Astex_2775 b88499b8b95431fae9aef0bf121d9b0b 211 TIGRFAM TIGR02001 gcw_chp: conserved hypothetical protein 1 211 8.9E-45 T 13-10-2018 IPR010239 Conserved hypothetical protein CHP02001 Astex_2775 b88499b8b95431fae9aef0bf121d9b0b 211 Gene3D G3DSA:2.40.160.10 8 211 1.2E-5 T 13-10-2018 IPR023614 Porin domain superfamily Astex_2567 143f3a255524d12a5b9dfbfce9a0b47f 416 SUPERFAMILY SSF52266 203 415 1.01E-47 T 13-10-2018 Astex_2567 143f3a255524d12a5b9dfbfce9a0b47f 416 Gene3D G3DSA:3.40.50.1110 197 415 9.9E-36 T 13-10-2018 IPR036514 SGNH hydrolase superfamily Astex_2567 143f3a255524d12a5b9dfbfce9a0b47f 416 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 208 404 1.1E-26 T 13-10-2018 IPR013830 SGNH hydrolase-type esterase domain Astex_0261 4c829b9b6e213cd16389aacafc655b7b 510 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 150 373 1.5E-72 T 13-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Astex_0261 4c829b9b6e213cd16389aacafc655b7b 510 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 380 504 6.5E-49 T 13-10-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_0261 4c829b9b6e213cd16389aacafc655b7b 510 SUPERFAMILY SSF50615 10 95 2.41E-25 T 13-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Astex_0261 4c829b9b6e213cd16389aacafc655b7b 510 Gene3D G3DSA:3.40.50.300 95 380 2.9E-133 T 13-10-2018 Astex_0261 4c829b9b6e213cd16389aacafc655b7b 510 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 25 93 3.0E-15 T 13-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Astex_0261 4c829b9b6e213cd16389aacafc655b7b 510 Gene3D G3DSA:1.20.150.20 381 510 1.4E-55 T 13-10-2018 IPR038376 ATP synthase, alpha subunit, C-terminal domain superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_0261 4c829b9b6e213cd16389aacafc655b7b 510 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 364 373 - T 13-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Astex_0261 4c829b9b6e213cd16389aacafc655b7b 510 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 509 9.0E-251 T 13-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_0261 4c829b9b6e213cd16389aacafc655b7b 510 PIRSF PIRSF039088 1 510 3.2E-279 T 13-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_0261 4c829b9b6e213cd16389aacafc655b7b 510 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 510 51.191 T 13-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_0261 4c829b9b6e213cd16389aacafc655b7b 510 Gene3D G3DSA:2.40.30.20 1 94 9.4E-36 T 13-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Astex_0261 4c829b9b6e213cd16389aacafc655b7b 510 SUPERFAMILY SSF52540 97 379 5.31E-102 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0261 4c829b9b6e213cd16389aacafc655b7b 510 SUPERFAMILY SSF47917 381 509 3.14E-48 T 13-10-2018 Astex_3587 f0688c23e5569462845094fd8848f722 341 Pfam PF06481 COX Aromatic Rich Motif 249 294 5.6E-12 T 13-10-2018 IPR010514 COX aromatic rich motif GO:0008827|GO:0016021|GO:0022900|GO:0055114 Astex_3587 f0688c23e5569462845094fd8848f722 341 TIGRFAM TIGR01433 CyoA: ubiquinol oxidase, subunit II 22 249 8.8E-106 T 13-10-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 Astex_3587 f0688c23e5569462845094fd8848f722 341 SUPERFAMILY SSF49503 131 288 6.42E-48 T 13-10-2018 IPR008972 Cupredoxin Astex_3587 f0688c23e5569462845094fd8848f722 341 PIRSF PIRSF000292 9 313 2.2E-121 T 13-10-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 Astex_3587 f0688c23e5569462845094fd8848f722 341 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 160 236 7.3E-7 T 13-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_3587 f0688c23e5569462845094fd8848f722 341 Gene3D G3DSA:1.10.287.90 33 118 6.6E-32 T 13-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_3587 f0688c23e5569462845094fd8848f722 341 SUPERFAMILY SSF81464 34 122 8.01E-23 T 13-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_3587 f0688c23e5569462845094fd8848f722 341 Gene3D G3DSA:2.60.40.420 119 290 1.1E-52 T 13-10-2018 IPR008972 Cupredoxin Astex_2943 31b202b4012c67fe9b7ba393e9e0ea9b 431 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 16 431 52.842 T 13-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 Astex_2943 31b202b4012c67fe9b7ba393e9e0ea9b 431 PIRSF PIRSF000412 3 431 1.0E-170 T 13-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 Astex_2943 31b202b4012c67fe9b7ba393e9e0ea9b 431 SUPERFAMILY SSF53383 8 431 8.21E-178 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Astex_2943 31b202b4012c67fe9b7ba393e9e0ea9b 431 Pfam PF00464 Serine hydroxymethyltransferase 18 394 1.3E-172 T 13-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 Astex_2943 31b202b4012c67fe9b7ba393e9e0ea9b 431 Gene3D G3DSA:3.90.1150.10 19 404 2.8E-181 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Astex_2943 31b202b4012c67fe9b7ba393e9e0ea9b 431 Gene3D G3DSA:3.40.640.10 46 297 2.8E-181 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Astex_2943 31b202b4012c67fe9b7ba393e9e0ea9b 431 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 231 247 - T 13-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 Astex_2656 478249296eca73165160f1aa7c8b5878 516 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 7 194 2.8E-68 T 13-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 Astex_2656 478249296eca73165160f1aa7c8b5878 516 SUPERFAMILY SSF52402 188 409 4.41E-57 T 13-10-2018 Astex_2656 478249296eca73165160f1aa7c8b5878 516 Pfam PF02540 NAD synthase 207 247 3.8E-6 T 13-10-2018 IPR022310 NAD/GMP synthase Astex_2656 478249296eca73165160f1aa7c8b5878 516 SUPERFAMILY SSF52317 4 228 5.47E-54 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Astex_2656 478249296eca73165160f1aa7c8b5878 516 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 204 516 5.3E-147 T 13-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 Astex_2656 478249296eca73165160f1aa7c8b5878 516 Gene3D G3DSA:3.40.50.880 1 196 1.6E-51 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Astex_2656 478249296eca73165160f1aa7c8b5878 516 Gene3D G3DSA:3.40.50.620 200 396 1.8E-74 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Astex_2656 478249296eca73165160f1aa7c8b5878 516 Gene3D G3DSA:3.30.300.10 397 516 7.4E-53 T 13-10-2018 Astex_2656 478249296eca73165160f1aa7c8b5878 516 Pfam PF00117 Glutamine amidotransferase class-I 9 191 1.6E-36 T 13-10-2018 IPR017926 Glutamine amidotransferase Astex_2656 478249296eca73165160f1aa7c8b5878 516 Pfam PF00958 GMP synthase C terminal domain 424 515 9.3E-44 T 13-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 Astex_2656 478249296eca73165160f1aa7c8b5878 516 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 4 516 53.707 T 13-10-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 Astex_2656 478249296eca73165160f1aa7c8b5878 516 PRINTS PR00096 Glutamine amidotransferase superfamily signature 77 88 5.9E-6 T 13-10-2018 Astex_2656 478249296eca73165160f1aa7c8b5878 516 PRINTS PR00096 Glutamine amidotransferase superfamily signature 168 181 5.9E-6 T 13-10-2018 Astex_2656 478249296eca73165160f1aa7c8b5878 516 PRINTS PR00096 Glutamine amidotransferase superfamily signature 51 60 5.9E-6 T 13-10-2018 Astex_2656 478249296eca73165160f1aa7c8b5878 516 SUPERFAMILY SSF54810 396 516 3.01E-51 T 13-10-2018 Astex_3350 a967526f782251d4d0f4612bf2d646ef 650 SUPERFAMILY SSF56935 34 650 2.29E-85 T 13-10-2018 Astex_3350 a967526f782251d4d0f4612bf2d646ef 650 Gene3D G3DSA:2.170.130.10 39 164 3.7E-27 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_3350 a967526f782251d4d0f4612bf2d646ef 650 Gene3D G3DSA:2.40.170.20 176 623 6.6E-42 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_3350 a967526f782251d4d0f4612bf2d646ef 650 Pfam PF07715 TonB-dependent Receptor Plug Domain 53 160 1.6E-19 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_3350 a967526f782251d4d0f4612bf2d646ef 650 Pfam PF00593 TonB dependent receptor 215 646 1.4E-29 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_3640 023c6ac54a6c2e1fdc012305a2de1d9e 785 SUPERFAMILY SSF49785 471 602 2.21E-23 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_3640 023c6ac54a6c2e1fdc012305a2de1d9e 785 Gene3D G3DSA:2.60.120.260 301 596 2.6E-76 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_3640 023c6ac54a6c2e1fdc012305a2de1d9e 785 Pfam PF00754 F5/8 type C domain 711 779 7.0E-8 T 13-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain Astex_3640 023c6ac54a6c2e1fdc012305a2de1d9e 785 Gene3D G3DSA:3.20.20.80 27 300 7.1E-89 T 13-10-2018 Astex_3640 023c6ac54a6c2e1fdc012305a2de1d9e 785 SUPERFAMILY SSF49785 710 779 1.28E-14 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_3640 023c6ac54a6c2e1fdc012305a2de1d9e 785 Gene3D G3DSA:2.60.120.260 376 511 2.6E-76 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_3640 023c6ac54a6c2e1fdc012305a2de1d9e 785 PRINTS PR00742 Glycosyl hydrolase family 35 signature 529 543 8.8E-47 T 13-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_3640 023c6ac54a6c2e1fdc012305a2de1d9e 785 PRINTS PR00742 Glycosyl hydrolase family 35 signature 177 192 8.8E-47 T 13-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_3640 023c6ac54a6c2e1fdc012305a2de1d9e 785 PRINTS PR00742 Glycosyl hydrolase family 35 signature 66 84 8.8E-47 T 13-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_3640 023c6ac54a6c2e1fdc012305a2de1d9e 785 PRINTS PR00742 Glycosyl hydrolase family 35 signature 555 571 8.8E-47 T 13-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_3640 023c6ac54a6c2e1fdc012305a2de1d9e 785 PRINTS PR00742 Glycosyl hydrolase family 35 signature 45 62 8.8E-47 T 13-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_3640 023c6ac54a6c2e1fdc012305a2de1d9e 785 PRINTS PR00742 Glycosyl hydrolase family 35 signature 260 275 8.8E-47 T 13-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_3640 023c6ac54a6c2e1fdc012305a2de1d9e 785 PRINTS PR00742 Glycosyl hydrolase family 35 signature 296 311 8.8E-47 T 13-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_3640 023c6ac54a6c2e1fdc012305a2de1d9e 785 PRINTS PR00742 Glycosyl hydrolase family 35 signature 320 336 8.8E-47 T 13-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_3640 023c6ac54a6c2e1fdc012305a2de1d9e 785 PRINTS PR00742 Glycosyl hydrolase family 35 signature 121 140 8.8E-47 T 13-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_3640 023c6ac54a6c2e1fdc012305a2de1d9e 785 SUPERFAMILY SSF51445 35 354 7.43E-85 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_3640 023c6ac54a6c2e1fdc012305a2de1d9e 785 Pfam PF01301 Glycosyl hydrolases family 35 42 349 9.6E-99 T 13-10-2018 IPR031330 Glycoside hydrolase 35, catalytic domain KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_3640 023c6ac54a6c2e1fdc012305a2de1d9e 785 Gene3D G3DSA:2.60.120.260 685 782 2.1E-18 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_3640 023c6ac54a6c2e1fdc012305a2de1d9e 785 ProSitePatterns PS01182 Glycosyl hydrolases family 35 putative active site. 179 191 - T 13-10-2018 IPR019801 Glycoside hydrolase, family 35, conserved site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_2845 6042e824b0397e7c8c7dd5f80a51f0fb 243 PIRSF PIRSF005650 4 243 1.4E-91 T 13-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 Astex_2845 6042e824b0397e7c8c7dd5f80a51f0fb 243 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 9 240 1.6E-99 T 13-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 Astex_2845 6042e824b0397e7c8c7dd5f80a51f0fb 243 Hamap MF_01220_B Uridylate kinase [pyrH]. 7 240 43.83 T 13-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 Astex_2845 6042e824b0397e7c8c7dd5f80a51f0fb 243 SUPERFAMILY SSF53633 7 240 3.14E-71 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Astex_2845 6042e824b0397e7c8c7dd5f80a51f0fb 243 Gene3D G3DSA:3.40.1160.10 2 242 8.5E-79 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Astex_2845 6042e824b0397e7c8c7dd5f80a51f0fb 243 Pfam PF00696 Amino acid kinase family 10 219 7.2E-30 T 13-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 Astex_0917 71b4dd78b4e68316881131b25c556f62 238 SUPERFAMILY SSF53254 1 226 4.5E-66 T 13-10-2018 IPR029033 Histidine phosphatase superfamily Astex_0917 71b4dd78b4e68316881131b25c556f62 238 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 1 225 40.758 T 13-10-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 Astex_0917 71b4dd78b4e68316881131b25c556f62 238 Gene3D G3DSA:3.40.50.1240 2 233 1.3E-74 T 13-10-2018 IPR029033 Histidine phosphatase superfamily Astex_0917 71b4dd78b4e68316881131b25c556f62 238 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 205 2.8E-33 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 Astex_0917 71b4dd78b4e68316881131b25c556f62 238 PIRSF PIRSF000709 2 107 1.0E-5 T 13-10-2018 Astex_0917 71b4dd78b4e68316881131b25c556f62 238 PIRSF PIRSF000709 167 235 6.4 T 13-10-2018 Astex_0917 71b4dd78b4e68316881131b25c556f62 238 SMART SM00855 3 186 2.0E-23 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 Astex_0917 71b4dd78b4e68316881131b25c556f62 238 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 3 228 1.4E-95 T 13-10-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 Astex_0917 71b4dd78b4e68316881131b25c556f62 238 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 13-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 Astex_2812 1bcd2395456d1c0d0d966f2c87a0b07d 163 SUPERFAMILY SSF54862 37 147 6.28E-29 T 13-10-2018 Astex_2812 1bcd2395456d1c0d0d966f2c87a0b07d 163 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 22 141 1.7E-49 T 13-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2812 1bcd2395456d1c0d0d966f2c87a0b07d 163 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 11 160 27.585 T 13-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2812 1bcd2395456d1c0d0d966f2c87a0b07d 163 Pfam PF12838 4Fe-4S dicluster domain 63 117 2.2E-13 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Astex_2812 1bcd2395456d1c0d0d966f2c87a0b07d 163 Gene3D G3DSA:3.30.70.3270 37 162 4.3E-43 T 13-10-2018 Astex_2812 1bcd2395456d1c0d0d966f2c87a0b07d 163 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 103 114 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Astex_1321 ac05eebce089280becb702c12bfa684f 317 Gene3D G3DSA:3.40.50.1000 37 222 1.9E-9 T 13-10-2018 IPR023214 HAD superfamily Astex_1321 ac05eebce089280becb702c12bfa684f 317 Pfam PF11019 Protein of unknown function (DUF2608) 49 282 2.0E-38 T 13-10-2018 IPR022565 Protein of unknown function DUF2608 Astex_0322 03d432532c59345835dac642f669d38b 225 Gene3D G3DSA:3.40.50.150 33 158 9.4E-8 T 13-10-2018 Astex_0322 03d432532c59345835dac642f669d38b 225 SUPERFAMILY SSF53335 27 124 1.49E-11 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Astex_0322 03d432532c59345835dac642f669d38b 225 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 115 121 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 Astex_0865 ff5fe6743069374a9abc870d22cb3947 401 Gene3D G3DSA:3.90.1150.10 27 393 1.0E-134 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Astex_0865 ff5fe6743069374a9abc870d22cb3947 401 SUPERFAMILY SSF53383 5 399 1.81E-111 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Astex_0865 ff5fe6743069374a9abc870d22cb3947 401 Gene3D G3DSA:3.40.640.10 64 287 1.0E-134 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Astex_0865 ff5fe6743069374a9abc870d22cb3947 401 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 237 250 - T 13-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 Astex_0865 ff5fe6743069374a9abc870d22cb3947 401 Pfam PF00155 Aminotransferase class I and II 32 393 2.4E-75 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Astex_3514 a8899886d9893b10ed84fac7f9cc42e9 445 Pfam PF04413 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) 36 212 2.5E-51 T 13-10-2018 IPR007507 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 Astex_3514 a8899886d9893b10ed84fac7f9cc42e9 445 Gene3D G3DSA:3.40.50.11720 35 213 7.9E-36 T 13-10-2018 IPR038107 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal domain superfamily KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 Astex_3514 a8899886d9893b10ed84fac7f9cc42e9 445 Gene3D G3DSA:3.40.50.2000 220 411 1.4E-48 T 13-10-2018 Astex_1655 5f587ed8fadfc7a2d38b10642a61070a 243 Pfam PF13280 WYL domain 141 237 2.7E-13 T 13-10-2018 IPR026881 WYL domain Astex_1655 5f587ed8fadfc7a2d38b10642a61070a 243 SUPERFAMILY SSF46785 1 62 1.72E-8 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_1655 5f587ed8fadfc7a2d38b10642a61070a 243 Gene3D G3DSA:1.10.10.10 1 64 1.1E-15 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1655 5f587ed8fadfc7a2d38b10642a61070a 243 Pfam PF08279 HTH domain 6 59 1.3E-15 T 13-10-2018 IPR013196 Helix-turn-helix, type 11 Astex_1634 d2a4071503c9d1eb1a68f0d2169f9feb 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 50 68 7.1E-58 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 Astex_1634 d2a4071503c9d1eb1a68f0d2169f9feb 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 303 329 7.1E-58 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 Astex_1634 d2a4071503c9d1eb1a68f0d2169f9feb 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 133 152 7.1E-58 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 Astex_1634 d2a4071503c9d1eb1a68f0d2169f9feb 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 188 208 7.1E-58 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 Astex_1634 d2a4071503c9d1eb1a68f0d2169f9feb 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 70 93 7.1E-58 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 Astex_1634 d2a4071503c9d1eb1a68f0d2169f9feb 347 Gene3D G3DSA:3.30.420.40 155 320 2.4E-137 T 13-10-2018 Astex_1634 d2a4071503c9d1eb1a68f0d2169f9feb 347 SUPERFAMILY SSF53067 150 334 4.02E-49 T 13-10-2018 Astex_1634 d2a4071503c9d1eb1a68f0d2169f9feb 347 SUPERFAMILY SSF53067 9 149 9.78E-38 T 13-10-2018 Astex_1634 d2a4071503c9d1eb1a68f0d2169f9feb 347 Gene3D G3DSA:3.30.420.40 13 331 2.4E-137 T 13-10-2018 Astex_1634 d2a4071503c9d1eb1a68f0d2169f9feb 347 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 9 335 2.3E-154 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 Astex_1634 d2a4071503c9d1eb1a68f0d2169f9feb 347 Pfam PF06723 MreB/Mbl protein 10 338 3.7E-148 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 Astex_1634 d2a4071503c9d1eb1a68f0d2169f9feb 347 Gene3D G3DSA:3.90.640.10 187 262 2.4E-137 T 13-10-2018 Astex_0860 cc65e0ac1e61ee98ce69caa8c05e3dd8 371 Pfam PF02445 Quinolinate synthetase A protein 51 345 7.5E-104 T 13-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 Astex_0860 cc65e0ac1e61ee98ce69caa8c05e3dd8 371 SUPERFAMILY SSF142754 48 347 2.48E-101 T 13-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 Astex_0860 cc65e0ac1e61ee98ce69caa8c05e3dd8 371 Gene3D G3DSA:3.40.50.10800 51 328 8.3E-105 T 13-10-2018 Astex_0860 cc65e0ac1e61ee98ce69caa8c05e3dd8 371 Gene3D G3DSA:3.40.50.10800 131 345 8.3E-105 T 13-10-2018 Astex_0860 cc65e0ac1e61ee98ce69caa8c05e3dd8 371 Gene3D G3DSA:3.40.50.10800 218 303 8.3E-105 T 13-10-2018 Astex_0860 cc65e0ac1e61ee98ce69caa8c05e3dd8 371 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 48 347 2.2E-90 T 13-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 Astex_0860 cc65e0ac1e61ee98ce69caa8c05e3dd8 371 Hamap MF_00568 Quinolinate synthase A [nadA]. 46 347 42.582 T 13-10-2018 IPR023066 Quinolinate synthase A, type 2 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 Astex_2625 733b192f7279500c3c6e2b1e8d24a01f 216 SUPERFAMILY SSF143456 23 215 1.31E-58 T 13-10-2018 Astex_2625 733b192f7279500c3c6e2b1e8d24a01f 216 Gene3D G3DSA:3.40.1740.10 18 216 2.0E-64 T 13-10-2018 Astex_2625 733b192f7279500c3c6e2b1e8d24a01f 216 Pfam PF02622 Uncharacterized ACR, COG1678 34 203 3.9E-49 T 13-10-2018 IPR003774 Protein of unknown function UPF0301 Astex_2625 733b192f7279500c3c6e2b1e8d24a01f 216 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 23 216 35.109 T 13-10-2018 IPR003774 Protein of unknown function UPF0301 Astex_2087 583dd4fe14e309f4ddd6bcd537758bfe 246 Gene3D G3DSA:1.20.1050.10 103 221 8.4E-75 T 13-10-2018 Astex_2087 583dd4fe14e309f4ddd6bcd537758bfe 246 SUPERFAMILY SSF52833 14 106 7.63E-17 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Astex_2087 583dd4fe14e309f4ddd6bcd537758bfe 246 SUPERFAMILY SSF47616 103 242 1.29E-22 T 13-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily Astex_2087 583dd4fe14e309f4ddd6bcd537758bfe 246 Pfam PF13417 Glutathione S-transferase, N-terminal domain 24 100 2.6E-13 T 13-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 Astex_2087 583dd4fe14e309f4ddd6bcd537758bfe 246 Pfam PF14497 Glutathione S-transferase, C-terminal domain 160 223 2.1E-8 T 13-10-2018 IPR004046 Glutathione S-transferase, C-terminal Astex_2087 583dd4fe14e309f4ddd6bcd537758bfe 246 Gene3D G3DSA:3.40.30.10 24 246 8.4E-75 T 13-10-2018 Astex_2701 e270e82459ae9635c13b472679306c29 245 SUPERFAMILY SSF51735 6 227 2.89E-56 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_2701 e270e82459ae9635c13b472679306c29 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 195 0.0046 T 13-10-2018 Astex_2701 e270e82459ae9635c13b472679306c29 245 Pfam PF00106 short chain dehydrogenase 10 202 3.2E-46 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2701 e270e82459ae9635c13b472679306c29 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Astex_2701 e270e82459ae9635c13b472679306c29 245 Gene3D G3DSA:3.40.50.720 2 235 3.4E-62 T 13-10-2018 Astex_2701 e270e82459ae9635c13b472679306c29 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 7.3E-19 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2701 e270e82459ae9635c13b472679306c29 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 7.3E-19 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2701 e270e82459ae9635c13b472679306c29 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 7.3E-19 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2701 e270e82459ae9635c13b472679306c29 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 7.3E-19 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2701 e270e82459ae9635c13b472679306c29 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 7.3E-19 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2701 e270e82459ae9635c13b472679306c29 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 7.3E-19 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1588 689463effe5e772b7107920247931e06 265 Pfam PF11738 Protein of unknown function (DUF3298) 154 238 1.4E-5 T 13-10-2018 IPR021729 Domain of unknown function DUF3298 Astex_1588 689463effe5e772b7107920247931e06 265 Gene3D G3DSA:3.90.640.20 208 254 6.4E-5 T 13-10-2018 IPR037126 PdaC/RsiV-like superfamily Astex_1588 689463effe5e772b7107920247931e06 265 Gene3D G3DSA:3.30.565.40 40 147 1.5E-9 T 13-10-2018 Astex_1588 689463effe5e772b7107920247931e06 265 Pfam PF13739 Domain of unknown function (DUF4163) 46 133 5.4E-8 T 13-10-2018 IPR025303 Deacetylase PdaC Astex_0812 72c8fdf8cc751334c3b0c9fc1eee9a9c 215 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 122 208 17.795 T 13-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 Astex_0812 72c8fdf8cc751334c3b0c9fc1eee9a9c 215 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 65 114 8.0E-15 T 13-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 Astex_0812 72c8fdf8cc751334c3b0c9fc1eee9a9c 215 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 42 114 6.1E-29 T 13-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 Astex_0812 72c8fdf8cc751334c3b0c9fc1eee9a9c 215 SUPERFAMILY SSF141734 19 124 4.58E-41 T 13-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 Astex_0812 72c8fdf8cc751334c3b0c9fc1eee9a9c 215 SUPERFAMILY SSF101386 124 212 1.29E-21 T 13-10-2018 Astex_0812 72c8fdf8cc751334c3b0c9fc1eee9a9c 215 Hamap MF_01019 Histidine biosynthesis bifunctional protein HisIE [hisI]. 17 213 33.442 T 13-10-2018 IPR023019 Histidine biosynthesis bifunctional protein HisIE GO:0000105|GO:0004635|GO:0004636 KEGG: 00340+3.6.1.31+3.5.4.19 Astex_0812 72c8fdf8cc751334c3b0c9fc1eee9a9c 215 Gene3D G3DSA:1.10.287.1080 123 214 3.7E-24 T 13-10-2018 Astex_0812 72c8fdf8cc751334c3b0c9fc1eee9a9c 215 Gene3D G3DSA:3.10.20.400 12 106 4.3E-33 T 13-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 Astex_0812 72c8fdf8cc751334c3b0c9fc1eee9a9c 215 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 127 207 1.2E-25 T 13-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 Astex_0812 72c8fdf8cc751334c3b0c9fc1eee9a9c 215 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 128 212 1.1E-12 T 13-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 Astex_2646 57d24411c97ae8139e12634948e08955 155 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 11 149 1.6E-45 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 Astex_2646 57d24411c97ae8139e12634948e08955 155 Gene3D G3DSA:2.40.100.10 2 153 9.1E-48 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily Astex_2646 57d24411c97ae8139e12634948e08955 155 PIRSF PIRSF001467 5 153 8.5E-32 T 13-10-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 Astex_2646 57d24411c97ae8139e12634948e08955 155 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 48 60 6.8E-14 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 Astex_2646 57d24411c97ae8139e12634948e08955 155 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 115 130 6.8E-14 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 Astex_2646 57d24411c97ae8139e12634948e08955 155 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 22 37 6.8E-14 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 Astex_2646 57d24411c97ae8139e12634948e08955 155 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 102 114 6.8E-14 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 Astex_2646 57d24411c97ae8139e12634948e08955 155 SUPERFAMILY SSF50891 6 152 2.34E-49 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily Astex_1048 f7d1218ef1056fcef63a6b00a08916da 443 PRINTS PR00344 Bacterial sensor protein C-terminal signature 389 407 2.0E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1048 f7d1218ef1056fcef63a6b00a08916da 443 PRINTS PR00344 Bacterial sensor protein C-terminal signature 356 370 2.0E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1048 f7d1218ef1056fcef63a6b00a08916da 443 PRINTS PR00344 Bacterial sensor protein C-terminal signature 374 384 2.0E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1048 f7d1218ef1056fcef63a6b00a08916da 443 PRINTS PR00344 Bacterial sensor protein C-terminal signature 418 431 2.0E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1048 f7d1218ef1056fcef63a6b00a08916da 443 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 325 433 3.6E-13 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_1048 f7d1218ef1056fcef63a6b00a08916da 443 SUPERFAMILY SSF47384 206 274 6.28E-7 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Astex_1048 f7d1218ef1056fcef63a6b00a08916da 443 Gene3D G3DSA:3.30.565.10 283 436 3.2E-24 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_1048 f7d1218ef1056fcef63a6b00a08916da 443 SUPERFAMILY SSF55874 284 433 9.82E-25 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_1048 f7d1218ef1056fcef63a6b00a08916da 443 SMART SM00387 319 434 2.0E-17 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_1048 f7d1218ef1056fcef63a6b00a08916da 443 Gene3D G3DSA:1.10.287.130 188 273 3.5E-8 T 13-10-2018 Astex_2512 e1c01647001e62f43aa8f5a7632c92e5 789 Pfam PF14498 Glycosyl hydrolase family 65, N-terminal domain 40 275 1.1E-68 T 13-10-2018 IPR027414 Glycosyl hydrolase family 95, N-terminal domain KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807 Astex_2512 e1c01647001e62f43aa8f5a7632c92e5 789 Gene3D G3DSA:1.50.10.10 49 746 2.2E-231 T 13-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 Astex_2512 e1c01647001e62f43aa8f5a7632c92e5 789 SUPERFAMILY SSF48208 282 759 2.04E-84 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 Astex_2512 e1c01647001e62f43aa8f5a7632c92e5 789 Gene3D G3DSA:2.60.40.1180 318 768 2.2E-231 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta Astex_2512 e1c01647001e62f43aa8f5a7632c92e5 789 PIRSF PIRSF007663 11 780 1.9E-277 T 13-10-2018 IPR016518 Alpha-L-fucosidase GO:0004560 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807 Astex_2512 e1c01647001e62f43aa8f5a7632c92e5 789 Gene3D G3DSA:2.70.98.50 53 317 2.2E-231 T 13-10-2018 Astex_3154 f708bc806c5e254097e8938c16557e88 330 Gene3D G3DSA:3.20.20.30 1 325 4.3E-95 T 13-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 Astex_3154 f708bc806c5e254097e8938c16557e88 330 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 4 322 6.5E-130 T 13-10-2018 IPR019949 Luciferase family oxidoreductase, group 1 Astex_3154 f708bc806c5e254097e8938c16557e88 330 SUPERFAMILY SSF51679 3 322 1.53E-82 T 13-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 Astex_3154 f708bc806c5e254097e8938c16557e88 330 Pfam PF00296 Luciferase-like monooxygenase 4 297 3.1E-37 T 13-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 Astex_1467 1536ba783ccaebf6602b158a71b688df 207 Gene3D G3DSA:1.10.10.60 6 61 2.8E-22 T 13-10-2018 Astex_1467 1536ba783ccaebf6602b158a71b688df 207 SUPERFAMILY SSF46689 6 87 3.06E-21 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Astex_1467 1536ba783ccaebf6602b158a71b688df 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 62 1.8E-18 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Astex_1467 1536ba783ccaebf6602b158a71b688df 207 Pfam PF14246 AefR-like transcriptional repressor, C-terminal region 149 203 1.1E-15 T 13-10-2018 IPR039536 Transcriptional regulator TetR, C-terminal, Proteobacteria type Astex_1467 1536ba783ccaebf6602b158a71b688df 207 Gene3D G3DSA:1.10.357.10 75 207 8.1E-34 T 13-10-2018 Astex_1467 1536ba783ccaebf6602b158a71b688df 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 9.0E-11 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Astex_1467 1536ba783ccaebf6602b158a71b688df 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 9.0E-11 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Astex_1467 1536ba783ccaebf6602b158a71b688df 207 SUPERFAMILY SSF48498 82 199 1.29E-8 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily Astex_0654 af16ff56ba2b3749c121d0d9e112dd9a 225 Pfam PF00072 Response regulator receiver domain 4 113 1.1E-25 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_0654 af16ff56ba2b3749c121d0d9e112dd9a 225 Gene3D G3DSA:1.10.10.10 126 225 7.4E-30 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_0654 af16ff56ba2b3749c121d0d9e112dd9a 225 Gene3D G3DSA:3.40.50.2300 1 125 2.6E-34 T 13-10-2018 Astex_0654 af16ff56ba2b3749c121d0d9e112dd9a 225 SMART SM00862 147 223 7.8E-21 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Astex_0654 af16ff56ba2b3749c121d0d9e112dd9a 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 223 4.0E-22 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Astex_0654 af16ff56ba2b3749c121d0d9e112dd9a 225 SMART SM00448 2 112 2.5E-38 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_0654 af16ff56ba2b3749c121d0d9e112dd9a 225 SUPERFAMILY SSF52172 1 185 4.27E-40 T 13-10-2018 IPR011006 CheY-like superfamily Astex_2256 64748ab3b60052042df04d76f723de11 677 SUPERFAMILY SSF101447 53 62 2.22E-5 T 13-10-2018 Astex_2256 64748ab3b60052042df04d76f723de11 677 SUPERFAMILY SSF56925 197 313 5.49E-6 T 13-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel Astex_2256 64748ab3b60052042df04d76f723de11 677 SUPERFAMILY SSF56925 503 645 1.65E-12 T 13-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel Astex_2256 64748ab3b60052042df04d76f723de11 677 Gene3D G3DSA:2.40.160.90 533 672 4.3E-12 T 13-10-2018 Astex_2256 64748ab3b60052042df04d76f723de11 677 Gene3D G3DSA:2.40.160.90 212 345 2.8E-11 T 13-10-2018 Astex_3120 e141a9b22bb1f10983676c6f3f9ae250 759 Pfam PF05746 DALR anticodon binding domain 646 749 5.5E-8 T 13-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 Astex_3120 e141a9b22bb1f10983676c6f3f9ae250 759 SUPERFAMILY SSF109604 333 482 2.83E-15 T 13-10-2018 Astex_3120 e141a9b22bb1f10983676c6f3f9ae250 759 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 1 758 21.967 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 Astex_3120 e141a9b22bb1f10983676c6f3f9ae250 759 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 4 616 1.9E-184 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 Astex_3120 e141a9b22bb1f10983676c6f3f9ae250 759 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 48 60 1.2E-27 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 Astex_3120 e141a9b22bb1f10983676c6f3f9ae250 759 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 307 323 1.2E-27 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 Astex_3120 e141a9b22bb1f10983676c6f3f9ae250 759 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 384 403 1.2E-27 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 Astex_3120 e141a9b22bb1f10983676c6f3f9ae250 759 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 5 18 1.2E-27 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 Astex_3120 e141a9b22bb1f10983676c6f3f9ae250 759 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 233 248 1.2E-27 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 Astex_3120 e141a9b22bb1f10983676c6f3f9ae250 759 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 3 496 1.1E-127 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 Astex_3026 97101dbf8a2a154dd7604619f31ac4b7 149 SUPERFAMILY SSF102400 2 139 2.48E-36 T 13-10-2018 IPR036768 DNA polymerase III subunit chi superfamily Astex_3026 97101dbf8a2a154dd7604619f31ac4b7 149 Gene3D G3DSA:3.40.50.10110 1 138 6.5E-20 T 13-10-2018 IPR036768 DNA polymerase III subunit chi superfamily Astex_3026 97101dbf8a2a154dd7604619f31ac4b7 149 Pfam PF04364 DNA polymerase III chi subunit, HolC 2 134 1.4E-32 T 13-10-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 Astex_3290 a35b1794169d0d80d7b778bede4d7e54 250 Gene3D G3DSA:1.10.10.10 147 219 1.7E-16 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_3290 a35b1794169d0d80d7b778bede4d7e54 250 SMART SM00419 164 212 7.1E-5 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 Astex_3290 a35b1794169d0d80d7b778bede4d7e54 250 SUPERFAMILY SSF46785 150 223 1.01E-15 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_3290 a35b1794169d0d80d7b778bede4d7e54 250 SUPERFAMILY SSF51206 10 130 6.88E-7 T 13-10-2018 IPR018490 Cyclic nucleotide-binding-like Astex_3290 a35b1794169d0d80d7b778bede4d7e54 250 Pfam PF13545 Crp-like helix-turn-helix domain 152 218 5.6E-15 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 Astex_3411 07e24ee55b60e5b2112be971a64dde07 190 Pfam PF02954 Bacterial regulatory protein, Fis family 148 188 5.2E-14 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Astex_3411 07e24ee55b60e5b2112be971a64dde07 190 Gene3D G3DSA:1.10.10.60 142 189 1.9E-15 T 13-10-2018 Astex_3411 07e24ee55b60e5b2112be971a64dde07 190 Gene3D G3DSA:3.40.50.2300 12 134 1.7E-26 T 13-10-2018 Astex_3411 07e24ee55b60e5b2112be971a64dde07 190 SMART SM00448 11 127 4.1E-21 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_3411 07e24ee55b60e5b2112be971a64dde07 190 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 171 190 1.1E-9 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Astex_3411 07e24ee55b60e5b2112be971a64dde07 190 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 154 171 1.1E-9 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Astex_3411 07e24ee55b60e5b2112be971a64dde07 190 SUPERFAMILY SSF46689 138 190 2.47E-12 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Astex_3411 07e24ee55b60e5b2112be971a64dde07 190 SUPERFAMILY SSF52172 14 136 2.28E-28 T 13-10-2018 IPR011006 CheY-like superfamily Astex_3411 07e24ee55b60e5b2112be971a64dde07 190 Pfam PF00072 Response regulator receiver domain 16 127 2.8E-20 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_2905 729e41dee0b7883a364e7a89689e1454 193 Pfam PF01638 HxlR-like helix-turn-helix 52 138 1.2E-16 T 13-10-2018 IPR002577 Helix-turn-helix, HxlR type Astex_2905 729e41dee0b7883a364e7a89689e1454 193 Gene3D G3DSA:1.10.10.10 35 187 8.6E-31 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_2905 729e41dee0b7883a364e7a89689e1454 193 SUPERFAMILY SSF46785 40 146 1.5E-26 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_0493 157bbb51d19d6db30743d12f1fb5958b 226 Gene3D G3DSA:1.10.357.10 24 226 4.1E-26 T 13-10-2018 Astex_0493 157bbb51d19d6db30743d12f1fb5958b 226 SUPERFAMILY SSF46689 24 108 2.77E-17 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Astex_0493 157bbb51d19d6db30743d12f1fb5958b 226 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 57 80 1.8E-8 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Astex_0493 157bbb51d19d6db30743d12f1fb5958b 226 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 49 1.8E-8 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Astex_0493 157bbb51d19d6db30743d12f1fb5958b 226 Pfam PF00440 Bacterial regulatory proteins, tetR family 36 80 1.7E-14 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Astex_2372 af37da70f2619ed2ef2ce375c7951e31 665 SUPERFAMILY SSF56935 33 663 2.34E-63 T 13-10-2018 Astex_2372 af37da70f2619ed2ef2ce375c7951e31 665 Pfam PF00593 TonB dependent receptor 241 663 1.5E-30 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_2372 af37da70f2619ed2ef2ce375c7951e31 665 Gene3D G3DSA:2.170.130.10 30 145 5.9E-12 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_2372 af37da70f2619ed2ef2ce375c7951e31 665 Pfam PF07715 TonB-dependent Receptor Plug Domain 44 139 1.9E-9 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_2372 af37da70f2619ed2ef2ce375c7951e31 665 Gene3D G3DSA:2.40.170.20 208 664 2.9E-47 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_1488 ca7b84dd43eafb88740dccc8bc7c94f4 189 SUPERFAMILY SSF55729 39 172 2.2E-10 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Astex_1488 ca7b84dd43eafb88740dccc8bc7c94f4 189 Gene3D G3DSA:3.40.630.30 30 158 3.4E-7 T 13-10-2018 Astex_1354 2e234cd3e4b4b0930ba3730fcec0f494 285 Pfam PF02616 Segregation and condensation protein ScpA 55 275 9.1E-12 T 13-10-2018 IPR003768 Segregation and condensation protein A Astex_0234 cb2852c5fbae6a6d864dedf873b02a9e 426 Gene3D G3DSA:1.20.1250.20 11 202 1.0E-39 T 13-10-2018 Astex_0234 cb2852c5fbae6a6d864dedf873b02a9e 426 Pfam PF07690 Major Facilitator Superfamily 21 366 6.8E-44 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Astex_0234 cb2852c5fbae6a6d864dedf873b02a9e 426 SUPERFAMILY SSF103473 6 423 2.88E-60 T 13-10-2018 IPR036259 MFS transporter superfamily Astex_0234 cb2852c5fbae6a6d864dedf873b02a9e 426 Gene3D G3DSA:1.20.1250.20 209 420 2.9E-19 T 13-10-2018 Astex_2811 55935486f155dc7568afbe52595d3eda 361 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 231 244 - T 13-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2811 55935486f155dc7568afbe52595d3eda 361 Pfam PF00146 NADH dehydrogenase 21 350 2.8E-120 T 13-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2811 55935486f155dc7568afbe52595d3eda 361 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 13 357 24.444 T 13-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_1881 2ded67324f71143a3a045aa110043fb5 296 Gene3D G3DSA:1.25.40.10 40 296 1.4E-43 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_1881 2ded67324f71143a3a045aa110043fb5 296 SMART SM00671 52 87 1.8 T 13-10-2018 IPR006597 Sel1-like repeat Astex_1881 2ded67324f71143a3a045aa110043fb5 296 SMART SM00671 122 158 0.012 T 13-10-2018 IPR006597 Sel1-like repeat Astex_1881 2ded67324f71143a3a045aa110043fb5 296 SMART SM00671 191 222 29.0 T 13-10-2018 IPR006597 Sel1-like repeat Astex_1881 2ded67324f71143a3a045aa110043fb5 296 SMART SM00671 223 258 0.15 T 13-10-2018 IPR006597 Sel1-like repeat Astex_1881 2ded67324f71143a3a045aa110043fb5 296 SUPERFAMILY SSF81901 47 254 2.68E-27 T 13-10-2018 Astex_1881 2ded67324f71143a3a045aa110043fb5 296 Pfam PF08238 Sel1 repeat 54 87 0.14 T 13-10-2018 IPR006597 Sel1-like repeat Astex_1881 2ded67324f71143a3a045aa110043fb5 296 Pfam PF08238 Sel1 repeat 223 253 0.0021 T 13-10-2018 IPR006597 Sel1-like repeat Astex_1881 2ded67324f71143a3a045aa110043fb5 296 Pfam PF08238 Sel1 repeat 206 222 4.6 T 13-10-2018 IPR006597 Sel1-like repeat Astex_1881 2ded67324f71143a3a045aa110043fb5 296 Pfam PF08238 Sel1 repeat 127 158 6.6E-5 T 13-10-2018 IPR006597 Sel1-like repeat Astex_2356 2dd3f184fd9388ec654efa00cb2e59ee 432 SUPERFAMILY SSF53623 11 286 5.34E-85 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Astex_2356 2dd3f184fd9388ec654efa00cb2e59ee 432 Pfam PF08245 Mur ligase middle domain 50 266 3.0E-9 T 13-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Astex_2356 2dd3f184fd9388ec654efa00cb2e59ee 432 PIRSF PIRSF001563 2 429 3.8E-109 T 13-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 Astex_2356 2dd3f184fd9388ec654efa00cb2e59ee 432 Gene3D G3DSA:3.40.1190.10 3 287 1.4E-89 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Astex_2356 2dd3f184fd9388ec654efa00cb2e59ee 432 TIGRFAM TIGR01499 folC: bifunctional protein FolC 27 425 1.5E-113 T 13-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 Astex_2356 2dd3f184fd9388ec654efa00cb2e59ee 432 SUPERFAMILY SSF53244 289 426 1.08E-20 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Astex_2356 2dd3f184fd9388ec654efa00cb2e59ee 432 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 140 155 - T 13-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 Astex_2356 2dd3f184fd9388ec654efa00cb2e59ee 432 Gene3D G3DSA:3.90.190.20 289 426 4.4E-19 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Astex_3338 b38b4e0c73fd37615be9a622fd6a5893 402 SUPERFAMILY SSF51604 98 386 1.01E-78 T 13-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily Astex_3338 b38b4e0c73fd37615be9a622fd6a5893 402 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 14 110 2.6E-31 T 13-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain Astex_3338 b38b4e0c73fd37615be9a622fd6a5893 402 SUPERFAMILY SSF54826 1 112 4.27E-34 T 13-10-2018 Astex_3338 b38b4e0c73fd37615be9a622fd6a5893 402 Pfam PF13378 Enolase C-terminal domain-like 135 377 6.0E-42 T 13-10-2018 IPR029065 Enolase C-terminal domain-like Astex_3338 b38b4e0c73fd37615be9a622fd6a5893 402 SMART SM00922 128 257 6.0E-16 T 13-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal Astex_3338 b38b4e0c73fd37615be9a622fd6a5893 402 Gene3D G3DSA:3.30.390.10 6 399 4.8E-174 T 13-10-2018 IPR029017 Enolase-like, N-terminal Astex_3338 b38b4e0c73fd37615be9a622fd6a5893 402 Gene3D G3DSA:3.20.20.120 105 367 4.8E-174 T 13-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily Astex_3338 b38b4e0c73fd37615be9a622fd6a5893 402 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 85 110 - T 13-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 Astex_1960 441fefac542f2bd3057e940bb4fd8985 864 Pfam PF00989 PAS fold 338 429 3.7E-8 T 13-10-2018 IPR013767 PAS fold GO:0006355 Astex_1960 441fefac542f2bd3057e940bb4fd8985 864 Gene3D G3DSA:3.30.450.20 453 573 4.1E-9 T 13-10-2018 Astex_1960 441fefac542f2bd3057e940bb4fd8985 864 SUPERFAMILY SSF55785 449 565 3.14E-10 T 13-10-2018 IPR035965 PAS domain superfamily Astex_1960 441fefac542f2bd3057e940bb4fd8985 864 Gene3D G3DSA:3.30.450.20 332 448 1.4E-15 T 13-10-2018 Astex_1960 441fefac542f2bd3057e940bb4fd8985 864 SUPERFAMILY SSF47384 601 686 6.67E-22 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Astex_1960 441fefac542f2bd3057e940bb4fd8985 864 SMART SM00388 615 684 9.1E-24 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_1960 441fefac542f2bd3057e940bb4fd8985 864 Pfam PF00512 His Kinase A (phospho-acceptor) domain 615 684 1.0E-18 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_1960 441fefac542f2bd3057e940bb4fd8985 864 SMART SM00387 729 841 1.2E-35 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_1960 441fefac542f2bd3057e940bb4fd8985 864 SMART SM00091 337 404 0.026 T 13-10-2018 IPR000014 PAS domain Astex_1960 441fefac542f2bd3057e940bb4fd8985 864 SMART SM00091 464 532 0.43 T 13-10-2018 IPR000014 PAS domain Astex_1960 441fefac542f2bd3057e940bb4fd8985 864 SUPERFAMILY SSF55785 327 450 9.42E-11 T 13-10-2018 IPR035965 PAS domain superfamily Astex_1960 441fefac542f2bd3057e940bb4fd8985 864 SUPERFAMILY SSF55874 673 842 1.83E-49 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_1960 441fefac542f2bd3057e940bb4fd8985 864 Gene3D G3DSA:1.10.287.130 597 685 1.7E-26 T 13-10-2018 Astex_1960 441fefac542f2bd3057e940bb4fd8985 864 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 730 840 1.9E-23 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_1960 441fefac542f2bd3057e940bb4fd8985 864 PRINTS PR00344 Bacterial sensor protein C-terminal signature 801 819 5.3E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1960 441fefac542f2bd3057e940bb4fd8985 864 PRINTS PR00344 Bacterial sensor protein C-terminal signature 766 780 5.3E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1960 441fefac542f2bd3057e940bb4fd8985 864 PRINTS PR00344 Bacterial sensor protein C-terminal signature 825 838 5.3E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1960 441fefac542f2bd3057e940bb4fd8985 864 Pfam PF12860 PAS fold 470 571 1.6E-8 T 13-10-2018 Astex_1960 441fefac542f2bd3057e940bb4fd8985 864 Gene3D G3DSA:3.30.565.10 686 844 3.3E-46 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_1975 f4cbcb921d7411a59dde1cb7ecb52d06 314 Pfam PF00756 Putative esterase 54 303 3.6E-26 T 13-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 Astex_1975 f4cbcb921d7411a59dde1cb7ecb52d06 314 Gene3D G3DSA:3.40.50.1820 49 311 1.3E-51 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1975 f4cbcb921d7411a59dde1cb7ecb52d06 314 SUPERFAMILY SSF53474 33 311 1.75E-41 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_0714 46fde7ae6079cb9b5bb31a0a4a90d98a 333 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 183 326 7.1E-61 T 13-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 Astex_0714 46fde7ae6079cb9b5bb31a0a4a90d98a 333 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 1 328 40.962 T 13-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 Astex_0714 46fde7ae6079cb9b5bb31a0a4a90d98a 333 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 14 326 7.2E-126 T 13-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 Astex_0714 46fde7ae6079cb9b5bb31a0a4a90d98a 333 Gene3D G3DSA:1.10.3730.40 182 332 2.1E-65 T 13-10-2018 Astex_0714 46fde7ae6079cb9b5bb31a0a4a90d98a 333 SUPERFAMILY SSF51735 2 182 3.56E-61 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_0714 46fde7ae6079cb9b5bb31a0a4a90d98a 333 Gene3D G3DSA:3.40.50.720 1 181 1.4E-67 T 13-10-2018 Astex_0714 46fde7ae6079cb9b5bb31a0a4a90d98a 333 SUPERFAMILY SSF48179 183 328 7.14E-64 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Astex_0714 46fde7ae6079cb9b5bb31a0a4a90d98a 333 PIRSF PIRSF000116 203 330 2.3E-10 T 13-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 Astex_0714 46fde7ae6079cb9b5bb31a0a4a90d98a 333 PIRSF PIRSF000116 4 207 4.8E-37 T 13-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 Astex_0714 46fde7ae6079cb9b5bb31a0a4a90d98a 333 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 14 177 4.2E-62 T 13-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 Astex_2868 8d318afe96b8ece79f8b4569243682cf 82 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 5 67 29.443 T 13-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 Astex_2868 8d318afe96b8ece79f8b4569243682cf 82 Pfam PF17209 Hfq protein 9 71 1.2E-32 T 13-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 Astex_2868 8d318afe96b8ece79f8b4569243682cf 82 Gene3D G3DSA:2.30.30.100 2 81 3.2E-34 T 13-10-2018 Astex_2868 8d318afe96b8ece79f8b4569243682cf 82 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 7 67 7.0E-33 T 13-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 Astex_2868 8d318afe96b8ece79f8b4569243682cf 82 SUPERFAMILY SSF50182 8 72 4.58E-25 T 13-10-2018 IPR010920 LSM domain superfamily Astex_2982 e80f1ba5607589efe39904bb1bb57d04 218 Gene3D G3DSA:1.20.1050.10 83 208 1.8E-21 T 13-10-2018 Astex_2982 e80f1ba5607589efe39904bb1bb57d04 218 SUPERFAMILY SSF52833 1 83 3.84E-22 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Astex_2982 e80f1ba5607589efe39904bb1bb57d04 218 Pfam PF02798 Glutathione S-transferase, N-terminal domain 3 73 6.1E-18 T 13-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 Astex_2982 e80f1ba5607589efe39904bb1bb57d04 218 SUPERFAMILY SSF47616 81 209 1.53E-18 T 13-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily Astex_2982 e80f1ba5607589efe39904bb1bb57d04 218 Gene3D G3DSA:3.40.30.10 1 82 5.8E-35 T 13-10-2018 Astex_3416 b3c7bc791d2c274ae1acef01b5e951be 783 Gene3D G3DSA:2.60.40.1180 317 756 6.7E-238 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta Astex_3416 b3c7bc791d2c274ae1acef01b5e951be 783 PIRSF PIRSF007663 14 781 5.9E-285 T 13-10-2018 IPR016518 Alpha-L-fucosidase GO:0004560 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807 Astex_3416 b3c7bc791d2c274ae1acef01b5e951be 783 Gene3D G3DSA:1.50.10.10 48 745 6.7E-238 T 13-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 Astex_3416 b3c7bc791d2c274ae1acef01b5e951be 783 Gene3D G3DSA:2.70.98.50 52 316 6.7E-238 T 13-10-2018 Astex_3416 b3c7bc791d2c274ae1acef01b5e951be 783 Pfam PF14498 Glycosyl hydrolase family 65, N-terminal domain 39 275 1.0E-76 T 13-10-2018 IPR027414 Glycosyl hydrolase family 95, N-terminal domain KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807 Astex_3416 b3c7bc791d2c274ae1acef01b5e951be 783 SUPERFAMILY SSF48208 278 757 1.45E-88 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 Astex_0950 3c0e227ee4f4a824e0fa5d76cd430f7f 127 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 17 119 2.2E-28 T 13-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0950 3c0e227ee4f4a824e0fa5d76cd430f7f 127 SUPERFAMILY SSF54843 10 122 2.35E-39 T 13-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 Astex_0950 3c0e227ee4f4a824e0fa5d76cd430f7f 127 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 13 122 23.966 T 13-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0950 3c0e227ee4f4a824e0fa5d76cd430f7f 127 Gene3D G3DSA:3.90.470.10 1 127 1.4E-39 T 13-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 Astex_0950 3c0e227ee4f4a824e0fa5d76cd430f7f 127 Pfam PF00237 Ribosomal protein L22p/L17e 18 119 3.1E-29 T 13-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 Astex_1193 dabb6f9c2f9f420b3b1829bc3b051b5c 77 SUPERFAMILY SSF50249 5 76 1.49E-24 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Astex_1193 dabb6f9c2f9f420b3b1829bc3b051b5c 77 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 5 77 25.944 T 13-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 Astex_1193 dabb6f9c2f9f420b3b1829bc3b051b5c 77 Gene3D G3DSA:2.40.50.140 4 77 4.7E-33 T 13-10-2018 Astex_1193 dabb6f9c2f9f420b3b1829bc3b051b5c 77 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 7 75 8.1E-30 T 13-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 Astex_1193 dabb6f9c2f9f420b3b1829bc3b051b5c 77 Pfam PF01176 Translation initiation factor 1A / IF-1 12 75 7.9E-27 T 13-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 Astex_2730 98e4b0dee6942109641546d5e8b02677 247 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 55 8.7E-8 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Astex_2730 98e4b0dee6942109641546d5e8b02677 247 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 55 71 8.7E-8 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Astex_2730 98e4b0dee6942109641546d5e8b02677 247 SMART SM00345 22 81 2.1E-19 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Astex_2730 98e4b0dee6942109641546d5e8b02677 247 Gene3D G3DSA:3.40.1410.10 87 247 2.6E-35 T 13-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily Astex_2730 98e4b0dee6942109641546d5e8b02677 247 SUPERFAMILY SSF64288 69 245 6.75E-40 T 13-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily Astex_2730 98e4b0dee6942109641546d5e8b02677 247 Pfam PF00392 Bacterial regulatory proteins, gntR family 22 81 3.2E-17 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Astex_2730 98e4b0dee6942109641546d5e8b02677 247 Pfam PF07702 UTRA domain 105 241 1.4E-29 T 13-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 Astex_2730 98e4b0dee6942109641546d5e8b02677 247 SMART SM00866 105 241 1.2E-30 T 13-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 Astex_2730 98e4b0dee6942109641546d5e8b02677 247 Gene3D G3DSA:1.10.10.10 18 86 1.2E-22 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_2730 98e4b0dee6942109641546d5e8b02677 247 SUPERFAMILY SSF46785 14 94 6.94E-21 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_1592 adfcdf0cf4a0404a7ea9d534fa3c83c2 954 SUPERFAMILY SSF63411 767 948 8.9E-17 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 Astex_1592 adfcdf0cf4a0404a7ea9d534fa3c83c2 954 SUPERFAMILY SSF63411 41 268 1.38E-33 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 Astex_1592 adfcdf0cf4a0404a7ea9d534fa3c83c2 954 Gene3D G3DSA:3.30.830.10 322 477 1.5E-12 T 13-10-2018 Astex_1592 adfcdf0cf4a0404a7ea9d534fa3c83c2 954 SUPERFAMILY SSF63411 352 482 2.32E-6 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 Astex_1592 adfcdf0cf4a0404a7ea9d534fa3c83c2 954 Pfam PF00675 Insulinase (Peptidase family M16) 59 198 1.8E-12 T 13-10-2018 IPR011765 Peptidase M16, N-terminal Astex_1592 adfcdf0cf4a0404a7ea9d534fa3c83c2 954 Gene3D G3DSA:3.30.830.10 32 272 3.8E-42 T 13-10-2018 Astex_1592 adfcdf0cf4a0404a7ea9d534fa3c83c2 954 Pfam PF05193 Peptidase M16 inactive domain 703 877 6.6E-7 T 13-10-2018 IPR007863 Peptidase M16, C-terminal Astex_1592 adfcdf0cf4a0404a7ea9d534fa3c83c2 954 Pfam PF05193 Peptidase M16 inactive domain 221 397 9.2E-14 T 13-10-2018 IPR007863 Peptidase M16, C-terminal Astex_1592 adfcdf0cf4a0404a7ea9d534fa3c83c2 954 Gene3D G3DSA:3.30.830.10 533 741 2.5E-13 T 13-10-2018 Astex_1592 adfcdf0cf4a0404a7ea9d534fa3c83c2 954 SUPERFAMILY SSF63411 530 742 9.6E-20 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 Astex_1592 adfcdf0cf4a0404a7ea9d534fa3c83c2 954 Gene3D G3DSA:3.30.830.10 768 948 3.6E-19 T 13-10-2018 Astex_2397 f1b8a4371331d1f4e2fd2e3ccee28eaa 358 Pfam PF03150 Di-haem cytochrome c peroxidase 70 215 1.0E-44 T 13-10-2018 IPR004852 Di-haem cytochrome c peroxidase GO:0016491|GO:0055114 Astex_2397 f1b8a4371331d1f4e2fd2e3ccee28eaa 358 PIRSF PIRSF000294 49 358 2.3E-84 T 13-10-2018 IPR026259 Di-c-type haem protein, MauG/cytochrome c peroxidase GO:0016491|GO:0020037|GO:0055114 Astex_2397 f1b8a4371331d1f4e2fd2e3ccee28eaa 358 SUPERFAMILY SSF46626 58 203 2.56E-43 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Astex_2397 f1b8a4371331d1f4e2fd2e3ccee28eaa 358 Gene3D G3DSA:1.10.760.10 205 358 3.9E-90 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Astex_2397 f1b8a4371331d1f4e2fd2e3ccee28eaa 358 SUPERFAMILY SSF46626 195 358 4.94E-36 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Astex_2397 f1b8a4371331d1f4e2fd2e3ccee28eaa 358 Gene3D G3DSA:1.10.760.10 65 204 3.9E-90 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Astex_2119 e621cf29ab5bd6e94be1595d873236e0 512 Gene3D G3DSA:2.160.20.10 75 465 6.2E-97 T 13-10-2018 IPR012334 Pectin lyase fold Astex_2119 e621cf29ab5bd6e94be1595d873236e0 512 ProSitePatterns PS00502 Polygalacturonase active site. 317 331 - T 13-10-2018 IPR000743 Glycoside hydrolase, family 28 GO:0004650|GO:0005975 Astex_2119 e621cf29ab5bd6e94be1595d873236e0 512 Pfam PF00295 Glycosyl hydrolases family 28 186 391 8.8E-31 T 13-10-2018 IPR000743 Glycoside hydrolase, family 28 GO:0004650|GO:0005975 Astex_2119 e621cf29ab5bd6e94be1595d873236e0 512 SMART SM00710 276 297 560.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat Astex_2119 e621cf29ab5bd6e94be1595d873236e0 512 SMART SM00710 337 358 730.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat Astex_2119 e621cf29ab5bd6e94be1595d873236e0 512 SMART SM00710 417 439 2000.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat Astex_2119 e621cf29ab5bd6e94be1595d873236e0 512 SMART SM00710 249 275 3300.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat Astex_2119 e621cf29ab5bd6e94be1595d873236e0 512 SMART SM00710 310 331 100.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat Astex_2119 e621cf29ab5bd6e94be1595d873236e0 512 SUPERFAMILY SSF51126 69 458 7.77E-76 T 13-10-2018 IPR011050 Pectin lyase fold/virulence factor Astex_2953 e250180da456ff494a0dfdab156ea555 244 Pfam PF04376 Arginine-tRNA-protein transferase, N terminus 19 88 6.2E-14 T 13-10-2018 IPR007471 N-end aminoacyl transferase, N-terminal GO:0004057|GO:0016598 MetaCyc: PWY-7802 Astex_2953 e250180da456ff494a0dfdab156ea555 244 SUPERFAMILY SSF55729 84 228 9.38E-27 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Astex_2953 e250180da456ff494a0dfdab156ea555 244 Pfam PF04377 Arginine-tRNA-protein transferase, C terminus 108 229 1.5E-34 T 13-10-2018 IPR007472 N-end rule aminoacyl transferase, C-terminal GO:0004057|GO:0016598 MetaCyc: PWY-7802 Astex_2953 e250180da456ff494a0dfdab156ea555 244 PIRSF PIRSF037208 1 244 5.8E-87 T 13-10-2018 IPR017138 Aspartate/glutamate leucyltransferase GO:0008914|GO:0071596 MetaCyc: PWY-7802 Astex_2953 e250180da456ff494a0dfdab156ea555 244 Hamap MF_00689 Aspartate/glutamate leucyltransferase [bpt]. 8 235 38.52 T 13-10-2018 IPR017138 Aspartate/glutamate leucyltransferase GO:0008914|GO:0071596 MetaCyc: PWY-7802 Astex_3544 8a0abfadcfcb8b197a3ad566a1a79750 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 168 195 - T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Astex_3544 8a0abfadcfcb8b197a3ad566a1a79750 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 208 3.7E-20 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Astex_3544 8a0abfadcfcb8b197a3ad566a1a79750 218 Gene3D G3DSA:3.40.50.12740 6 212 1.2E-62 T 13-10-2018 Astex_3544 8a0abfadcfcb8b197a3ad566a1a79750 218 SMART SM00448 6 119 1.2E-34 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_3544 8a0abfadcfcb8b197a3ad566a1a79750 218 SUPERFAMILY SSF52172 4 172 3.47E-32 T 13-10-2018 IPR011006 CheY-like superfamily Astex_3544 8a0abfadcfcb8b197a3ad566a1a79750 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 4.4E-14 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Astex_3544 8a0abfadcfcb8b197a3ad566a1a79750 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 4.4E-14 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Astex_3544 8a0abfadcfcb8b197a3ad566a1a79750 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 4.4E-14 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Astex_3544 8a0abfadcfcb8b197a3ad566a1a79750 218 Pfam PF00072 Response regulator receiver domain 8 119 2.2E-27 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_3544 8a0abfadcfcb8b197a3ad566a1a79750 218 SMART SM00421 151 208 7.1E-26 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Astex_1968 07d544f9998a0e133051fe70cf8ffcca 489 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 424 1.2E-7 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1968 07d544f9998a0e133051fe70cf8ffcca 489 PRINTS PR00344 Bacterial sensor protein C-terminal signature 473 486 1.2E-7 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1968 07d544f9998a0e133051fe70cf8ffcca 489 PRINTS PR00344 Bacterial sensor protein C-terminal signature 443 461 1.2E-7 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1968 07d544f9998a0e133051fe70cf8ffcca 489 Gene3D G3DSA:1.20.1480.50 185 265 2.3E-5 T 13-10-2018 Astex_1968 07d544f9998a0e133051fe70cf8ffcca 489 SUPERFAMILY SSF47384 244 327 4.12E-10 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Astex_1968 07d544f9998a0e133051fe70cf8ffcca 489 SMART SM00304 207 260 1.5E-4 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Astex_1968 07d544f9998a0e133051fe70cf8ffcca 489 SUPERFAMILY SSF55874 320 486 1.57E-32 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_1968 07d544f9998a0e133051fe70cf8ffcca 489 Gene3D G3DSA:3.30.565.10 332 486 1.9E-31 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_1968 07d544f9998a0e133051fe70cf8ffcca 489 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 374 470 4.2E-18 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_1968 07d544f9998a0e133051fe70cf8ffcca 489 SMART SM00387 373 489 1.8E-27 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_1968 07d544f9998a0e133051fe70cf8ffcca 489 Gene3D G3DSA:1.10.287.130 267 329 7.2E-9 T 13-10-2018 Astex_1968 07d544f9998a0e133051fe70cf8ffcca 489 SMART SM00388 261 328 4.0E-5 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_2047 99cf3727594ac24edf7a89e3bb6a95a6 373 Pfam PF02515 CoA-transferase family III 11 369 5.0E-124 T 13-10-2018 IPR003673 CoA-transferase family III GO:0003824 Astex_2047 99cf3727594ac24edf7a89e3bb6a95a6 373 SUPERFAMILY SSF89796 9 369 8.37E-130 T 13-10-2018 IPR023606 CoA-transferase family III domain superfamily Astex_2047 99cf3727594ac24edf7a89e3bb6a95a6 373 Gene3D G3DSA:3.40.50.10540 10 354 2.4E-138 T 13-10-2018 IPR023606 CoA-transferase family III domain superfamily Astex_2047 99cf3727594ac24edf7a89e3bb6a95a6 373 Gene3D G3DSA:3.30.1540.10 232 323 2.4E-138 T 13-10-2018 Astex_1856 7b548bcac1558eb915a79d6c6ff99861 94 Pfam PF06961 Protein of unknown function (DUF1294) 15 69 7.2E-21 T 13-10-2018 IPR010718 Protein of unknown function DUF1294 Astex_1856 7b548bcac1558eb915a79d6c6ff99861 94 PIRSF PIRSF002599 5 92 4.2E-11 T 13-10-2018 IPR012156 Cold shock, CspA GO:0003676 Astex_1286 17caa9726e4922f488b0a23d2f41b53d 611 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 42 57 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site Astex_1286 17caa9726e4922f488b0a23d2f41b53d 611 Pfam PF00009 Elongation factor Tu GTP binding domain 2 197 2.7E-53 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Astex_1286 17caa9726e4922f488b0a23d2f41b53d 611 Gene3D G3DSA:3.30.70.870 312 597 6.4E-125 T 13-10-2018 Astex_1286 17caa9726e4922f488b0a23d2f41b53d 611 Gene3D G3DSA:2.40.50.250 490 606 6.4E-125 T 13-10-2018 Astex_1286 17caa9726e4922f488b0a23d2f41b53d 611 Pfam PF03144 Elongation factor Tu domain 2 223 295 3.2E-7 T 13-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 Astex_1286 17caa9726e4922f488b0a23d2f41b53d 611 SUPERFAMILY SSF54980 406 519 4.7E-24 T 13-10-2018 IPR035647 EF-G domain III/V-like Astex_1286 17caa9726e4922f488b0a23d2f41b53d 611 Pfam PF00679 Elongation factor G C-terminus 405 489 5.3E-20 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like Astex_1286 17caa9726e4922f488b0a23d2f41b53d 611 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 1 144 1.2E-23 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Astex_1286 17caa9726e4922f488b0a23d2f41b53d 611 Gene3D G3DSA:2.40.30.10 203 305 7.7E-27 T 13-10-2018 Astex_1286 17caa9726e4922f488b0a23d2f41b53d 611 Gene3D G3DSA:3.40.50.300 1 200 2.0E-61 T 13-10-2018 Astex_1286 17caa9726e4922f488b0a23d2f41b53d 611 SUPERFAMILY SSF50447 154 304 9.59E-25 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Astex_1286 17caa9726e4922f488b0a23d2f41b53d 611 PRINTS PR00315 GTP-binding elongation factor signature 73 83 6.0E-13 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Astex_1286 17caa9726e4922f488b0a23d2f41b53d 611 PRINTS PR00315 GTP-binding elongation factor signature 5 18 6.0E-13 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Astex_1286 17caa9726e4922f488b0a23d2f41b53d 611 PRINTS PR00315 GTP-binding elongation factor signature 49 57 6.0E-13 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Astex_1286 17caa9726e4922f488b0a23d2f41b53d 611 PRINTS PR00315 GTP-binding elongation factor signature 125 134 6.0E-13 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Astex_1286 17caa9726e4922f488b0a23d2f41b53d 611 Gene3D G3DSA:3.30.70.240 395 489 6.4E-125 T 13-10-2018 Astex_1286 17caa9726e4922f488b0a23d2f41b53d 611 SMART SM00838 405 491 0.0066 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like Astex_1286 17caa9726e4922f488b0a23d2f41b53d 611 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 3 606 3.2E-279 T 13-10-2018 IPR006298 GTP-binding protein TypA GO:0005525 Astex_1286 17caa9726e4922f488b0a23d2f41b53d 611 SUPERFAMILY SSF54980 308 393 1.15E-13 T 13-10-2018 IPR035647 EF-G domain III/V-like Astex_1286 17caa9726e4922f488b0a23d2f41b53d 611 SUPERFAMILY SSF52540 2 180 3.6E-52 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1204 d30add5f6b202a61dd687902f2a9046a 224 Gene3D G3DSA:2.40.100.10 55 220 5.3E-32 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily Astex_1204 d30add5f6b202a61dd687902f2a9046a 224 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 59 199 9.1E-27 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 Astex_1204 d30add5f6b202a61dd687902f2a9046a 224 SUPERFAMILY SSF50891 54 200 3.65E-29 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily Astex_1049 a74f893456bae58439142b4b30d80e91 176 SUPERFAMILY SSF52172 7 117 1.11E-30 T 13-10-2018 IPR011006 CheY-like superfamily Astex_1049 a74f893456bae58439142b4b30d80e91 176 Pfam PF00072 Response regulator receiver domain 7 115 3.3E-23 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1049 a74f893456bae58439142b4b30d80e91 176 Pfam PF02954 Bacterial regulatory protein, Fis family 133 172 7.7E-10 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Astex_1049 a74f893456bae58439142b4b30d80e91 176 Gene3D G3DSA:3.40.50.2300 6 119 6.9E-31 T 13-10-2018 Astex_1049 a74f893456bae58439142b4b30d80e91 176 SMART SM00448 4 115 3.6E-25 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1049 a74f893456bae58439142b4b30d80e91 176 SUPERFAMILY SSF46689 92 173 4.61E-14 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Astex_1049 a74f893456bae58439142b4b30d80e91 176 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 156 176 9.4E-6 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Astex_1049 a74f893456bae58439142b4b30d80e91 176 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 139 156 9.4E-6 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Astex_1049 a74f893456bae58439142b4b30d80e91 176 Gene3D G3DSA:1.10.10.60 120 175 5.3E-18 T 13-10-2018 Astex_0931 4862e0bf5bd68e8111bf9f5d1bfffebe 273 SUPERFAMILY SSF58113 111 255 5.1E-5 T 13-10-2018 Astex_0931 4862e0bf5bd68e8111bf9f5d1bfffebe 273 Gene3D G3DSA:1.20.120.20 101 264 6.2E-6 T 13-10-2018 Astex_0968 9f388c7452a657f7edae63de500c1c5f 129 PIRSF PIRSF002131 1 129 1.8E-53 T 13-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 Astex_0968 9f388c7452a657f7edae63de500c1c5f 129 SUPERFAMILY SSF53137 14 129 4.38E-49 T 13-10-2018 Astex_0968 9f388c7452a657f7edae63de500c1c5f 129 Gene3D G3DSA:3.30.420.80 1 129 5.5E-55 T 13-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 Astex_0968 9f388c7452a657f7edae63de500c1c5f 129 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 129 33.559 T 13-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 Astex_0968 9f388c7452a657f7edae63de500c1c5f 129 ProSitePatterns PS00054 Ribosomal protein S11 signature. 97 119 - T 13-10-2018 IPR018102 Ribosomal S11, conserved site Astex_0968 9f388c7452a657f7edae63de500c1c5f 129 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 10 126 3.3E-58 T 13-10-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_0968 9f388c7452a657f7edae63de500c1c5f 129 Pfam PF00411 Ribosomal protein S11 19 128 3.8E-51 T 13-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 Astex_2530 5adae8f6602cf532ef2b34e0280dc8bf 109 PRINTS PR00189 Transthyretin signature 87 109 2.4E-8 T 13-10-2018 IPR000895 Transthyretin/hydroxyisourate hydrolase Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 Astex_2530 5adae8f6602cf532ef2b34e0280dc8bf 109 PRINTS PR00189 Transthyretin signature 2 22 2.4E-8 T 13-10-2018 IPR000895 Transthyretin/hydroxyisourate hydrolase Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 Astex_2530 5adae8f6602cf532ef2b34e0280dc8bf 109 SUPERFAMILY SSF49472 3 109 1.44E-35 T 13-10-2018 IPR036817 Transthyretin/hydroxyisourate hydrolase domain superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 Astex_2530 5adae8f6602cf532ef2b34e0280dc8bf 109 Pfam PF00576 HIUase/Transthyretin family 3 108 4.8E-30 T 13-10-2018 IPR023416 Transthyretin/hydroxyisourate hydrolase domain Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 Astex_2530 5adae8f6602cf532ef2b34e0280dc8bf 109 TIGRFAM TIGR02962 hdxy_isourate: hydroxyisourate hydrolase 2 109 7.3E-32 T 13-10-2018 IPR014306 Hydroxyisourate hydrolase GO:0006144|GO:0033971 KEGG: 00230+3.5.2.17|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 Astex_2530 5adae8f6602cf532ef2b34e0280dc8bf 109 Gene3D G3DSA:2.60.40.180 1 109 6.6E-34 T 13-10-2018 IPR036817 Transthyretin/hydroxyisourate hydrolase domain superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 Astex_2530 5adae8f6602cf532ef2b34e0280dc8bf 109 ProSitePatterns PS00769 Transthyretin signature 2. 92 104 - T 13-10-2018 IPR023419 Transthyretin, conserved site Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 Astex_3516 a017d91597652084854120181910a9eb 616 Gene3D G3DSA:3.40.50.300 359 611 3.4E-91 T 13-10-2018 Astex_3516 a017d91597652084854120181910a9eb 616 SUPERFAMILY SSF90123 25 352 5.89E-57 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Astex_3516 a017d91597652084854120181910a9eb 616 SMART SM00382 387 573 1.1E-18 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_3516 a017d91597652084854120181910a9eb 616 Pfam PF00005 ABC transporter 378 527 2.2E-33 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_3516 a017d91597652084854120181910a9eb 616 Gene3D G3DSA:1.20.1560.10 6 350 1.7E-55 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Astex_3516 a017d91597652084854120181910a9eb 616 Pfam PF00664 ABC transporter transmembrane region 36 312 2.8E-34 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 Astex_3516 a017d91597652084854120181910a9eb 616 ProSitePatterns PS00211 ABC transporters family signature. 499 513 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Astex_3516 a017d91597652084854120181910a9eb 616 SUPERFAMILY SSF52540 360 598 2.07E-91 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1612 5ad7ee2f1729dff7dd8ffcafa6b6e664 859 SMART SM00382 595 766 1.8E-6 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_1612 5ad7ee2f1729dff7dd8ffcafa6b6e664 859 SMART SM00382 197 343 8.5E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_1612 5ad7ee2f1729dff7dd8ffcafa6b6e664 859 SUPERFAMILY SSF52540 544 847 1.46E-82 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1612 5ad7ee2f1729dff7dd8ffcafa6b6e664 859 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 629 647 - T 13-10-2018 IPR028299 ClpA/B, conserved site 2 Astex_1612 5ad7ee2f1729dff7dd8ffcafa6b6e664 859 SUPERFAMILY SSF52540 158 543 6.92E-101 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1612 5ad7ee2f1729dff7dd8ffcafa6b6e664 859 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 764 844 5.5E-24 T 13-10-2018 IPR019489 Clp ATPase, C-terminal Astex_1612 5ad7ee2f1729dff7dd8ffcafa6b6e664 859 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 202 334 1.6E-13 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Astex_1612 5ad7ee2f1729dff7dd8ffcafa6b6e664 859 Pfam PF07724 AAA domain (Cdc48 subfamily) 594 757 3.2E-56 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Astex_1612 5ad7ee2f1729dff7dd8ffcafa6b6e664 859 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 66 2.0E-12 T 13-10-2018 IPR004176 Clp, N-terminal Astex_1612 5ad7ee2f1729dff7dd8ffcafa6b6e664 859 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 98 143 4.4E-6 T 13-10-2018 IPR004176 Clp, N-terminal Astex_1612 5ad7ee2f1729dff7dd8ffcafa6b6e664 859 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 706 720 5.1E-42 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 Astex_1612 5ad7ee2f1729dff7dd8ffcafa6b6e664 859 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 644 662 5.1E-42 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 Astex_1612 5ad7ee2f1729dff7dd8ffcafa6b6e664 859 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 599 617 5.1E-42 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 Astex_1612 5ad7ee2f1729dff7dd8ffcafa6b6e664 859 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 673 691 5.1E-42 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 Astex_1612 5ad7ee2f1729dff7dd8ffcafa6b6e664 859 SMART SM01086 764 853 5.0E-33 T 13-10-2018 IPR019489 Clp ATPase, C-terminal Astex_1612 5ad7ee2f1729dff7dd8ffcafa6b6e664 859 SUPERFAMILY SSF81923 4 154 6.08E-33 T 13-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 Astex_1612 5ad7ee2f1729dff7dd8ffcafa6b6e664 859 Gene3D G3DSA:3.40.50.300 548 762 5.1E-86 T 13-10-2018 Astex_1612 5ad7ee2f1729dff7dd8ffcafa6b6e664 859 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 293 305 - T 13-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 Astex_1612 5ad7ee2f1729dff7dd8ffcafa6b6e664 859 Gene3D G3DSA:1.10.8.60 764 856 3.6E-25 T 13-10-2018 Astex_1612 5ad7ee2f1729dff7dd8ffcafa6b6e664 859 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 7 853 0.0 T 13-10-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0042026 Astex_1612 5ad7ee2f1729dff7dd8ffcafa6b6e664 859 Gene3D G3DSA:3.40.50.300 342 542 3.5E-73 T 13-10-2018 Astex_1612 5ad7ee2f1729dff7dd8ffcafa6b6e664 859 Gene3D G3DSA:3.40.50.300 148 341 1.0E-73 T 13-10-2018 Astex_1612 5ad7ee2f1729dff7dd8ffcafa6b6e664 859 Gene3D G3DSA:1.10.1780.10 1 147 7.9E-30 T 13-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 Astex_2380 924d5a69cf31e9befaec376598efa913 293 SUPERFAMILY SSF81624 2 158 1.7E-29 T 13-10-2018 IPR035937 MutM-like, N-terminal Astex_2380 924d5a69cf31e9befaec376598efa913 293 Gene3D G3DSA:3.20.190.10 1 151 1.2E-31 T 13-10-2018 IPR035937 MutM-like, N-terminal Astex_2380 924d5a69cf31e9befaec376598efa913 293 SMART SM00898 2 134 1.6E-35 T 13-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 Astex_2380 924d5a69cf31e9befaec376598efa913 293 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 292 40.137 T 13-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 Astex_2380 924d5a69cf31e9befaec376598efa913 293 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 291 1.2E-72 T 13-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 Astex_2380 924d5a69cf31e9befaec376598efa913 293 SUPERFAMILY SSF46946 150 239 1.27E-26 T 13-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 Astex_2380 924d5a69cf31e9befaec376598efa913 293 Gene3D G3DSA:1.10.8.50 160 292 2.7E-45 T 13-10-2018 Astex_2380 924d5a69cf31e9befaec376598efa913 293 Pfam PF06827 Zinc finger found in FPG and IleRS 263 292 7.0E-8 T 13-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 Astex_2380 924d5a69cf31e9befaec376598efa913 293 SUPERFAMILY SSF57716 238 292 2.82E-15 T 13-10-2018 Astex_2380 924d5a69cf31e9befaec376598efa913 293 ProSitePatterns PS01242 Zinc finger FPG-type signature. 265 291 - T 13-10-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 Astex_2380 924d5a69cf31e9befaec376598efa913 293 SMART SM01232 150 242 3.1E-41 T 13-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 Astex_2380 924d5a69cf31e9befaec376598efa913 293 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 150 239 4.3E-23 T 13-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 Astex_2380 924d5a69cf31e9befaec376598efa913 293 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 133 1.6E-28 T 13-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 Astex_2058 cef50f7b3ebc30f952476737d0d2a143 337 SUPERFAMILY SSF53822 61 334 2.52E-59 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Astex_2058 cef50f7b3ebc30f952476737d0d2a143 337 Gene3D G3DSA:3.40.50.2300 54 305 2.6E-62 T 13-10-2018 Astex_2058 cef50f7b3ebc30f952476737d0d2a143 337 Gene3D G3DSA:3.40.50.2300 161 291 2.6E-62 T 13-10-2018 Astex_2058 cef50f7b3ebc30f952476737d0d2a143 337 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 1.1E-17 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Astex_2058 cef50f7b3ebc30f952476737d0d2a143 337 Gene3D G3DSA:1.10.260.40 1 53 3.1E-22 T 13-10-2018 Astex_2058 cef50f7b3ebc30f952476737d0d2a143 337 SMART SM00354 1 71 4.1E-24 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Astex_2058 cef50f7b3ebc30f952476737d0d2a143 337 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 1.6E-5 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Astex_2058 cef50f7b3ebc30f952476737d0d2a143 337 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 1.6E-5 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Astex_2058 cef50f7b3ebc30f952476737d0d2a143 337 SUPERFAMILY SSF47413 1 57 7.15E-17 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Astex_2058 cef50f7b3ebc30f952476737d0d2a143 337 Pfam PF13377 Periplasmic binding protein-like domain 169 331 4.4E-32 T 13-10-2018 Astex_2055 8888562d1ca6eeb3571232d385ecce02 153 Pfam PF13744 Helix-turn-helix domain 34 85 6.3E-8 T 13-10-2018 IPR039554 HigA2-like, helix-turn-helix domain Astex_2055 8888562d1ca6eeb3571232d385ecce02 153 SUPERFAMILY SSF47413 33 91 9.92E-11 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Astex_2055 8888562d1ca6eeb3571232d385ecce02 153 SMART SM00530 31 88 5.9E-6 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Astex_2055 8888562d1ca6eeb3571232d385ecce02 153 Gene3D G3DSA:1.10.260.40 27 90 9.8E-12 T 13-10-2018 Astex_2055 8888562d1ca6eeb3571232d385ecce02 153 TIGRFAM TIGR02612 mob_myst_A: mobile mystery protein A 10 151 5.3E-41 T 13-10-2018 IPR013435 Mobile mystery protein A Astex_2339 f4fdceb31fd3ebee980bdf61262be9a7 321 Gene3D G3DSA:3.90.1200.10 106 321 3.7E-68 T 13-10-2018 Astex_2339 f4fdceb31fd3ebee980bdf61262be9a7 321 Gene3D G3DSA:3.30.200.20 1 104 2.1E-29 T 13-10-2018 Astex_2339 f4fdceb31fd3ebee980bdf61262be9a7 321 SUPERFAMILY SSF56112 5 314 1.53E-73 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily Astex_2339 f4fdceb31fd3ebee980bdf61262be9a7 321 Hamap MF_00301 Homoserine kinase [thrB]. 1 321 119.56 T 13-10-2018 IPR005280 Homoserine kinase, type II GO:0004413|GO:0009088 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 Astex_2339 f4fdceb31fd3ebee980bdf61262be9a7 321 Pfam PF01636 Phosphotransferase enzyme family 27 259 3.3E-37 T 13-10-2018 IPR002575 Aminoglycoside phosphotransferase Astex_2339 f4fdceb31fd3ebee980bdf61262be9a7 321 TIGRFAM TIGR00938 thrB_alt: homoserine kinase 1 309 6.1E-95 T 13-10-2018 IPR005280 Homoserine kinase, type II GO:0004413|GO:0009088 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 Astex_3004 59fa72a2a4a963ec9e6316651b7ccade 67 Gene3D G3DSA:3.10.20.30 4 66 1.4E-18 T 13-10-2018 IPR012675 Beta-grasp domain superfamily Astex_3004 59fa72a2a4a963ec9e6316651b7ccade 67 Pfam PF02597 ThiS family 4 66 3.6E-10 T 13-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 Astex_3004 59fa72a2a4a963ec9e6316651b7ccade 67 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 4 66 5.3E-20 T 13-10-2018 IPR010035 ThiS, thiamine-biosynthesis Astex_3004 59fa72a2a4a963ec9e6316651b7ccade 67 SUPERFAMILY SSF54285 3 65 8.04E-16 T 13-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp Astex_2042 2bf5af5cd210efd46b82602fae5c0657 362 Pfam PF11899 Protein of unknown function (DUF3419) 10 322 9.0E-50 T 13-10-2018 IPR021829 Protein of unknown function DUF3419 Astex_1310 15f1ca2daeb9a7a9133558671e81445b 151 Pfam PF13404 AsnC-type helix-turn-helix domain 2 43 5.4E-19 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 Astex_1310 15f1ca2daeb9a7a9133558671e81445b 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 48 4.4E-13 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 Astex_1310 15f1ca2daeb9a7a9133558671e81445b 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 29 4.4E-13 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 Astex_1310 15f1ca2daeb9a7a9133558671e81445b 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 2 18 4.4E-13 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 Astex_1310 15f1ca2daeb9a7a9133558671e81445b 151 SUPERFAMILY SSF54909 65 151 1.02E-20 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel Astex_1310 15f1ca2daeb9a7a9133558671e81445b 151 Gene3D G3DSA:1.10.10.10 1 55 1.2E-22 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1310 15f1ca2daeb9a7a9133558671e81445b 151 SMART SM00344 2 111 7.1E-43 T 13-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 Astex_1310 15f1ca2daeb9a7a9133558671e81445b 151 SUPERFAMILY SSF46785 1 60 6.5E-17 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_1310 15f1ca2daeb9a7a9133558671e81445b 151 Pfam PF01037 Lrp/AsnC ligand binding domain 68 142 6.7E-21 T 13-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Astex_1310 15f1ca2daeb9a7a9133558671e81445b 151 Gene3D G3DSA:3.30.70.920 56 139 1.5E-22 T 13-10-2018 Astex_3569 8917f941bea17c7a4f22f4cde0f297e5 411 Gene3D G3DSA:3.40.50.300 114 395 2.6E-59 T 13-10-2018 Astex_3569 8917f941bea17c7a4f22f4cde0f297e5 411 SUPERFAMILY SSF52540 112 365 3.43E-46 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_3569 8917f941bea17c7a4f22f4cde0f297e5 411 SUPERFAMILY SSF46955 52 103 2.7E-5 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily Astex_3569 8917f941bea17c7a4f22f4cde0f297e5 411 Pfam PF13614 AAA domain 117 298 7.4E-34 T 13-10-2018 IPR025669 AAA domain Astex_0178 67691924c01ca81cfde25f08740d9921 1072 Pfam PF00009 Elongation factor Tu GTP binding domain 576 733 6.1E-34 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Astex_0178 67691924c01ca81cfde25f08740d9921 1072 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 488 1072 6.3E-237 T 13-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 Astex_0178 67691924c01ca81cfde25f08740d9921 1072 ProSitePatterns PS01176 Initiation factor 2 signature. 1023 1045 - T 13-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 Astex_0178 67691924c01ca81cfde25f08740d9921 1072 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 574 731 2.0E-31 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Astex_0178 67691924c01ca81cfde25f08740d9921 1072 Pfam PF11987 Translation-initiation factor 2 857 961 1.2E-38 T 13-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 Astex_0178 67691924c01ca81cfde25f08740d9921 1072 SUPERFAMILY SSF52156 855 978 9.81E-36 T 13-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily Astex_0178 67691924c01ca81cfde25f08740d9921 1072 SUPERFAMILY SSF50447 744 828 6.19E-24 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Astex_0178 67691924c01ca81cfde25f08740d9921 1072 Gene3D G3DSA:3.40.50.300 569 743 2.6E-70 T 13-10-2018 Astex_0178 67691924c01ca81cfde25f08740d9921 1072 SUPERFAMILY SSF52540 572 744 2.48E-50 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0178 67691924c01ca81cfde25f08740d9921 1072 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 24 1070 16.89 T 13-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 Astex_0178 67691924c01ca81cfde25f08740d9921 1072 Pfam PF08364 Bacterial translation initiation factor IF-2 associated region 20 55 4.9E-8 T 13-10-2018 IPR013575 Initiation factor 2 associated domain, bacterial Astex_0178 67691924c01ca81cfde25f08740d9921 1072 Gene3D G3DSA:2.40.30.10 744 854 2.1E-41 T 13-10-2018 Astex_0178 67691924c01ca81cfde25f08740d9921 1072 Gene3D G3DSA:2.40.30.10 973 1071 1.8E-30 T 13-10-2018 Astex_0178 67691924c01ca81cfde25f08740d9921 1072 SUPERFAMILY SSF50447 973 1070 4.71E-26 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Astex_0178 67691924c01ca81cfde25f08740d9921 1072 Gene3D G3DSA:3.40.50.10050 865 972 2.6E-38 T 13-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily Astex_0178 67691924c01ca81cfde25f08740d9921 1072 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 496 545 1.6E-12 T 13-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal Astex_2365 63a70932bf04468fac00b9ff289f903b 562 SUPERFAMILY SSF50249 194 281 9.73E-27 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Astex_2365 63a70932bf04468fac00b9ff289f903b 562 SUPERFAMILY SSF50249 259 366 1.58E-25 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Astex_2365 63a70932bf04468fac00b9ff289f903b 562 SMART SM00316 25 91 3.4E-6 T 13-10-2018 IPR022967 RNA-binding domain, S1 Astex_2365 63a70932bf04468fac00b9ff289f903b 562 SMART SM00316 194 264 1.1E-27 T 13-10-2018 IPR022967 RNA-binding domain, S1 Astex_2365 63a70932bf04468fac00b9ff289f903b 562 SMART SM00316 366 438 1.7E-19 T 13-10-2018 IPR022967 RNA-binding domain, S1 Astex_2365 63a70932bf04468fac00b9ff289f903b 562 SMART SM00316 107 175 2.8E-7 T 13-10-2018 IPR022967 RNA-binding domain, S1 Astex_2365 63a70932bf04468fac00b9ff289f903b 562 SMART SM00316 279 351 4.5E-22 T 13-10-2018 IPR022967 RNA-binding domain, S1 Astex_2365 63a70932bf04468fac00b9ff289f903b 562 SMART SM00316 451 525 3.1E-17 T 13-10-2018 IPR022967 RNA-binding domain, S1 Astex_2365 63a70932bf04468fac00b9ff289f903b 562 PIRSF PIRSF002111 1 539 3.8E-192 T 13-10-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 Astex_2365 63a70932bf04468fac00b9ff289f903b 562 Gene3D G3DSA:2.40.50.140 104 189 1.6E-5 T 13-10-2018 Astex_2365 63a70932bf04468fac00b9ff289f903b 562 Gene3D G3DSA:2.40.50.140 13 103 3.0E-14 T 13-10-2018 Astex_2365 63a70932bf04468fac00b9ff289f903b 562 Pfam PF00575 S1 RNA binding domain 26 90 8.2E-7 T 13-10-2018 IPR003029 S1 domain GO:0003676 Astex_2365 63a70932bf04468fac00b9ff289f903b 562 Pfam PF00575 S1 RNA binding domain 194 264 2.8E-21 T 13-10-2018 IPR003029 S1 domain GO:0003676 Astex_2365 63a70932bf04468fac00b9ff289f903b 562 Pfam PF00575 S1 RNA binding domain 450 525 8.7E-15 T 13-10-2018 IPR003029 S1 domain GO:0003676 Astex_2365 63a70932bf04468fac00b9ff289f903b 562 Pfam PF00575 S1 RNA binding domain 364 438 5.0E-19 T 13-10-2018 IPR003029 S1 domain GO:0003676 Astex_2365 63a70932bf04468fac00b9ff289f903b 562 Pfam PF00575 S1 RNA binding domain 107 175 1.4E-10 T 13-10-2018 IPR003029 S1 domain GO:0003676 Astex_2365 63a70932bf04468fac00b9ff289f903b 562 Pfam PF00575 S1 RNA binding domain 279 351 5.6E-19 T 13-10-2018 IPR003029 S1 domain GO:0003676 Astex_2365 63a70932bf04468fac00b9ff289f903b 562 SUPERFAMILY SSF50249 14 116 1.01E-17 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Astex_2365 63a70932bf04468fac00b9ff289f903b 562 SUPERFAMILY SSF50249 446 541 1.03E-16 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Astex_2365 63a70932bf04468fac00b9ff289f903b 562 SUPERFAMILY SSF50249 107 188 7.86E-14 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Astex_2365 63a70932bf04468fac00b9ff289f903b 562 SUPERFAMILY SSF50249 351 440 1.78E-20 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Astex_2365 63a70932bf04468fac00b9ff289f903b 562 TIGRFAM TIGR00717 rpsA: ribosomal protein bS1 10 525 7.0E-193 T 13-10-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 Astex_2365 63a70932bf04468fac00b9ff289f903b 562 Gene3D G3DSA:2.40.50.140 359 442 1.8E-21 T 13-10-2018 Astex_2365 63a70932bf04468fac00b9ff289f903b 562 PRINTS PR00681 Ribosomal protein S1 signature 45 59 8.2E-82 T 13-10-2018 Astex_2365 63a70932bf04468fac00b9ff289f903b 562 PRINTS PR00681 Ribosomal protein S1 signature 112 128 8.2E-82 T 13-10-2018 Astex_2365 63a70932bf04468fac00b9ff289f903b 562 PRINTS PR00681 Ribosomal protein S1 signature 88 107 8.2E-82 T 13-10-2018 Astex_2365 63a70932bf04468fac00b9ff289f903b 562 PRINTS PR00681 Ribosomal protein S1 signature 159 179 8.2E-82 T 13-10-2018 Astex_2365 63a70932bf04468fac00b9ff289f903b 562 PRINTS PR00681 Ribosomal protein S1 signature 27 45 8.2E-82 T 13-10-2018 Astex_2365 63a70932bf04468fac00b9ff289f903b 562 PRINTS PR00681 Ribosomal protein S1 signature 130 147 8.2E-82 T 13-10-2018 Astex_2365 63a70932bf04468fac00b9ff289f903b 562 PRINTS PR00681 Ribosomal protein S1 signature 334 352 8.2E-82 T 13-10-2018 Astex_2365 63a70932bf04468fac00b9ff289f903b 562 PRINTS PR00681 Ribosomal protein S1 signature 294 313 8.2E-82 T 13-10-2018 Astex_2365 63a70932bf04468fac00b9ff289f903b 562 PRINTS PR00681 Ribosomal protein S1 signature 216 237 8.2E-82 T 13-10-2018 Astex_2365 63a70932bf04468fac00b9ff289f903b 562 Gene3D G3DSA:2.40.50.140 191 272 1.6E-28 T 13-10-2018 Astex_2365 63a70932bf04468fac00b9ff289f903b 562 Gene3D G3DSA:2.40.50.140 273 358 2.3E-28 T 13-10-2018 Astex_2365 63a70932bf04468fac00b9ff289f903b 562 Gene3D G3DSA:2.40.50.140 447 533 4.8E-15 T 13-10-2018 Astex_1401 41d149ecc5191239d7163dc05a779833 640 SUPERFAMILY SSF52518 6 381 8.84E-79 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold Astex_1401 41d149ecc5191239d7163dc05a779833 640 SUPERFAMILY SSF52518 317 505 9.25E-55 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold Astex_1401 41d149ecc5191239d7163dc05a779833 640 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 12 627 3.1E-234 T 13-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 Astex_1401 41d149ecc5191239d7163dc05a779833 640 SUPERFAMILY SSF52922 491 628 2.09E-34 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Astex_1401 41d149ecc5191239d7163dc05a779833 640 Pfam PF02780 Transketolase, C-terminal domain 496 619 5.7E-29 T 13-10-2018 IPR033248 Transketolase, C-terminal domain Astex_1401 41d149ecc5191239d7163dc05a779833 640 Gene3D G3DSA:3.40.50.970 316 492 1.4E-62 T 13-10-2018 Astex_1401 41d149ecc5191239d7163dc05a779833 640 Gene3D G3DSA:3.40.50.920 496 628 7.2E-37 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Astex_1401 41d149ecc5191239d7163dc05a779833 640 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 9 282 1.4E-114 T 13-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 Astex_1401 41d149ecc5191239d7163dc05a779833 640 ProSitePatterns PS00801 Transketolase signature 1. 34 53 - T 13-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 Astex_1401 41d149ecc5191239d7163dc05a779833 640 SMART SM00861 319 484 7.4E-61 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain Astex_1401 41d149ecc5191239d7163dc05a779833 640 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 8 628 44.632 T 13-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 Astex_1401 41d149ecc5191239d7163dc05a779833 640 Pfam PF02779 Transketolase, pyrimidine binding domain 319 479 6.9E-36 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain Astex_1838 ce759869d8192af158ce715f1ac5b56e 153 PIRSF PIRSF027377 3 139 2.6E-49 T 13-10-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 Astex_1838 ce759869d8192af158ce715f1ac5b56e 153 Pfam PF14489 QueF-like protein 57 135 4.9E-31 T 13-10-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 Astex_1838 ce759869d8192af158ce715f1ac5b56e 153 Gene3D G3DSA:3.30.1130.10 18 139 4.3E-40 T 13-10-2018 Astex_1838 ce759869d8192af158ce715f1ac5b56e 153 Hamap MF_00818 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 153 64.551 T 13-10-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 Astex_1838 ce759869d8192af158ce715f1ac5b56e 153 TIGRFAM TIGR03139 QueF-II: 7-cyano-7-deazaguanine reductase 23 133 5.2E-44 T 13-10-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 Astex_1838 ce759869d8192af158ce715f1ac5b56e 153 SUPERFAMILY SSF55620 24 133 1.19E-25 T 13-10-2018 Astex_0527 466f7ab76ba0ce68e83c69c27e2f325c 143 Gene3D G3DSA:3.10.580.10 1 142 3.0E-42 T 13-10-2018 Astex_0527 466f7ab76ba0ce68e83c69c27e2f325c 143 Pfam PF00571 CBS domain 13 61 1.2E-8 T 13-10-2018 IPR000644 CBS domain Astex_0527 466f7ab76ba0ce68e83c69c27e2f325c 143 Pfam PF00571 CBS domain 72 124 3.4E-11 T 13-10-2018 IPR000644 CBS domain Astex_0527 466f7ab76ba0ce68e83c69c27e2f325c 143 SMART SM00116 13 61 1.6E-10 T 13-10-2018 IPR000644 CBS domain Astex_0527 466f7ab76ba0ce68e83c69c27e2f325c 143 SMART SM00116 79 126 1.3E-4 T 13-10-2018 IPR000644 CBS domain Astex_0527 466f7ab76ba0ce68e83c69c27e2f325c 143 SUPERFAMILY SSF54631 13 139 6.95E-30 T 13-10-2018 Astex_2984 99a5c42ed2ebeec18e57340d629a5a3d 546 Gene3D G3DSA:1.20.1740.10 25 513 5.6E-110 T 13-10-2018 Astex_2984 99a5c42ed2ebeec18e57340d629a5a3d 546 PIRSF PIRSF006060 12 536 3.0E-87 T 13-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 Astex_2984 99a5c42ed2ebeec18e57340d629a5a3d 546 Pfam PF13520 Amino acid permease 31 501 2.6E-57 T 13-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 Astex_3481 fc2c65f241f369ceed9ae1f0e1119e9c 368 ProSitePatterns PS00789 Chorismate synthase signature 3. 327 343 - T 13-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 Astex_3481 fc2c65f241f369ceed9ae1f0e1119e9c 368 ProSitePatterns PS00788 Chorismate synthase signature 2. 124 140 - T 13-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 Astex_3481 fc2c65f241f369ceed9ae1f0e1119e9c 368 Hamap MF_00300 Chorismate synthase [aroC]. 10 360 35.951 T 13-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 Astex_3481 fc2c65f241f369ceed9ae1f0e1119e9c 368 PIRSF PIRSF001456 3 364 4.3E-135 T 13-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 Astex_3481 fc2c65f241f369ceed9ae1f0e1119e9c 368 Gene3D G3DSA:3.60.150.10 1 366 9.9E-144 T 13-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 Astex_3481 fc2c65f241f369ceed9ae1f0e1119e9c 368 Pfam PF01264 Chorismate synthase 10 353 7.8E-135 T 13-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 Astex_3481 fc2c65f241f369ceed9ae1f0e1119e9c 368 SUPERFAMILY SSF103263 3 358 1.44E-140 T 13-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 Astex_3481 fc2c65f241f369ceed9ae1f0e1119e9c 368 ProSitePatterns PS00787 Chorismate synthase signature 1. 16 31 - T 13-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 Astex_3481 fc2c65f241f369ceed9ae1f0e1119e9c 368 TIGRFAM TIGR00033 aroC: chorismate synthase 10 358 7.4E-133 T 13-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 Astex_3374 a03e5322db0d4fd74a0896792865c8a3 358 Gene3D G3DSA:3.40.190.10 34 332 3.1E-119 T 13-10-2018 Astex_3374 a03e5322db0d4fd74a0896792865c8a3 358 PIRSF PIRSF002756 2 345 2.9E-105 T 13-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 Astex_3374 a03e5322db0d4fd74a0896792865c8a3 358 Gene3D G3DSA:3.40.190.10 108 285 3.1E-119 T 13-10-2018 Astex_3374 a03e5322db0d4fd74a0896792865c8a3 358 SUPERFAMILY SSF53850 34 342 5.83E-97 T 13-10-2018 Astex_3374 a03e5322db0d4fd74a0896792865c8a3 358 Pfam PF12849 PBP superfamily domain 25 315 2.0E-61 T 13-10-2018 IPR024370 PBP domain Astex_3374 a03e5322db0d4fd74a0896792865c8a3 358 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 34 342 4.3E-118 T 13-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 Astex_3552 145a255dcf5b101a90ed2e90dd147a01 408 Gene3D G3DSA:1.50.10.100 44 404 6.2E-128 T 13-10-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 Astex_3552 145a255dcf5b101a90ed2e90dd147a01 408 SUPERFAMILY SSF48230 84 358 6.13E-51 T 13-10-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 Astex_3552 145a255dcf5b101a90ed2e90dd147a01 408 Pfam PF05426 Alginate lyase 77 356 2.9E-74 T 13-10-2018 IPR008397 Alginate lyase domain GO:0016829|GO:0042597 KEGG: 00051+4.2.2.3|MetaCyc: PWY-6986 Astex_2012 b12a518af9f81858ed123c9ea65ea40a 498 SUPERFAMILY SSF50494 60 278 2.03E-62 T 13-10-2018 IPR009003 Peptidase S1, PA clan Astex_2012 b12a518af9f81858ed123c9ea65ea40a 498 Gene3D G3DSA:2.40.10.120 61 280 5.4E-78 T 13-10-2018 Astex_2012 b12a518af9f81858ed123c9ea65ea40a 498 Gene3D G3DSA:2.30.42.10 400 498 7.6E-17 T 13-10-2018 Astex_2012 b12a518af9f81858ed123c9ea65ea40a 498 Gene3D G3DSA:2.30.42.10 282 383 2.7E-24 T 13-10-2018 Astex_2012 b12a518af9f81858ed123c9ea65ea40a 498 PRINTS PR00834 HtrA/DegQ protease family signature 219 236 2.2E-52 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Astex_2012 b12a518af9f81858ed123c9ea65ea40a 498 PRINTS PR00834 HtrA/DegQ protease family signature 145 165 2.2E-52 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Astex_2012 b12a518af9f81858ed123c9ea65ea40a 498 PRINTS PR00834 HtrA/DegQ protease family signature 124 136 2.2E-52 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Astex_2012 b12a518af9f81858ed123c9ea65ea40a 498 PRINTS PR00834 HtrA/DegQ protease family signature 327 339 2.2E-52 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Astex_2012 b12a518af9f81858ed123c9ea65ea40a 498 PRINTS PR00834 HtrA/DegQ protease family signature 241 258 2.2E-52 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Astex_2012 b12a518af9f81858ed123c9ea65ea40a 498 PRINTS PR00834 HtrA/DegQ protease family signature 185 209 2.2E-52 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Astex_2012 b12a518af9f81858ed123c9ea65ea40a 498 SUPERFAMILY SSF50156 403 496 2.23E-14 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 Astex_2012 b12a518af9f81858ed123c9ea65ea40a 498 Pfam PF13365 Trypsin-like peptidase domain 115 248 2.3E-31 T 13-10-2018 Astex_2012 b12a518af9f81858ed123c9ea65ea40a 498 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 62 491 7.0E-131 T 13-10-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 Astex_2012 b12a518af9f81858ed123c9ea65ea40a 498 SUPERFAMILY SSF50156 245 370 1.69E-21 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 Astex_2012 b12a518af9f81858ed123c9ea65ea40a 498 Pfam PF13180 PDZ domain 287 376 1.2E-18 T 13-10-2018 IPR001478 PDZ domain GO:0005515 Astex_2012 b12a518af9f81858ed123c9ea65ea40a 498 Pfam PF13180 PDZ domain 403 490 5.8E-8 T 13-10-2018 IPR001478 PDZ domain GO:0005515 Astex_2012 b12a518af9f81858ed123c9ea65ea40a 498 SMART SM00228 287 369 2.5E-13 T 13-10-2018 IPR001478 PDZ domain GO:0005515 Astex_2012 b12a518af9f81858ed123c9ea65ea40a 498 SMART SM00228 403 488 3.6E-10 T 13-10-2018 IPR001478 PDZ domain GO:0005515 Astex_1093 7f644eed01948962a3973ee572b92977 811 SUPERFAMILY SSF52540 157 404 1.61E-40 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1093 7f644eed01948962a3973ee572b92977 811 Pfam PF00271 Helicase conserved C-terminal domain 171 278 2.8E-11 T 13-10-2018 IPR001650 Helicase, C-terminal Astex_1093 7f644eed01948962a3973ee572b92977 811 SUPERFAMILY SSF52540 20 134 1.65E-8 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1093 7f644eed01948962a3973ee572b92977 811 Gene3D G3DSA:3.40.50.300 12 160 5.7E-28 T 13-10-2018 Astex_1093 7f644eed01948962a3973ee572b92977 811 SMART SM00490 190 279 6.8E-17 T 13-10-2018 IPR001650 Helicase, C-terminal Astex_1093 7f644eed01948962a3973ee572b92977 811 Gene3D G3DSA:3.40.50.300 161 301 6.5E-36 T 13-10-2018 Astex_2704 c94124bfc79ee16c900fe180ca6224b5 457 SUPERFAMILY SSF54211 257 450 9.1E-37 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Astex_2704 c94124bfc79ee16c900fe180ca6224b5 457 SUPERFAMILY SSF52540 73 290 8.44E-48 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2704 c94124bfc79ee16c900fe180ca6224b5 457 PRINTS PR01874 DNA repair protein radA signature 324 347 8.3E-87 T 13-10-2018 Astex_2704 c94124bfc79ee16c900fe180ca6224b5 457 PRINTS PR01874 DNA repair protein radA signature 176 200 8.3E-87 T 13-10-2018 Astex_2704 c94124bfc79ee16c900fe180ca6224b5 457 PRINTS PR01874 DNA repair protein radA signature 126 143 8.3E-87 T 13-10-2018 Astex_2704 c94124bfc79ee16c900fe180ca6224b5 457 PRINTS PR01874 DNA repair protein radA signature 84 112 8.3E-87 T 13-10-2018 Astex_2704 c94124bfc79ee16c900fe180ca6224b5 457 PRINTS PR01874 DNA repair protein radA signature 10 34 8.3E-87 T 13-10-2018 Astex_2704 c94124bfc79ee16c900fe180ca6224b5 457 PRINTS PR01874 DNA repair protein radA signature 250 276 8.3E-87 T 13-10-2018 Astex_2704 c94124bfc79ee16c900fe180ca6224b5 457 PRINTS PR01874 DNA repair protein radA signature 215 243 8.3E-87 T 13-10-2018 Astex_2704 c94124bfc79ee16c900fe180ca6224b5 457 SMART SM00382 92 246 5.3E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_2704 c94124bfc79ee16c900fe180ca6224b5 457 Hamap MF_01498 DNA repair protein RadA [radA]. 21 454 41.752 T 13-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 Astex_2704 c94124bfc79ee16c900fe180ca6224b5 457 Gene3D G3DSA:3.30.230.10 337 454 4.5E-12 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Astex_2704 c94124bfc79ee16c900fe180ca6224b5 457 Pfam PF06745 KaiC 77 253 1.0E-16 T 13-10-2018 IPR014774 KaiC-like domain Astex_2704 c94124bfc79ee16c900fe180ca6224b5 457 Gene3D G3DSA:3.40.50.300 68 283 1.1E-43 T 13-10-2018 Astex_2704 c94124bfc79ee16c900fe180ca6224b5 457 Pfam PF13541 Subunit ChlI of Mg-chelatase 348 430 3.2E-8 T 13-10-2018 Astex_2704 c94124bfc79ee16c900fe180ca6224b5 457 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 441 3.1E-163 T 13-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 Astex_1295 25c4a0114e0a56eab152522a8136fac6 332 Gene3D G3DSA:3.10.520.20 26 331 8.1E-90 T 13-10-2018 Astex_1295 25c4a0114e0a56eab152522a8136fac6 332 Pfam PF02424 ApbE family 39 309 1.2E-69 T 13-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 Astex_1295 25c4a0114e0a56eab152522a8136fac6 332 PIRSF PIRSF006268 18 330 1.3E-64 T 13-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 Astex_1295 25c4a0114e0a56eab152522a8136fac6 332 SUPERFAMILY SSF143631 31 331 5.75E-81 T 13-10-2018 IPR003374 ApbE-like superfamily Astex_2051 765230d37a1b71c8a3dad7ae42cf30c8 298 SUPERFAMILY SSF53850 96 295 5.61E-39 T 13-10-2018 Astex_2051 765230d37a1b71c8a3dad7ae42cf30c8 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 70 1.2E-19 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_2051 765230d37a1b71c8a3dad7ae42cf30c8 298 Pfam PF03466 LysR substrate binding domain 94 293 1.1E-37 T 13-10-2018 IPR005119 LysR, substrate-binding Astex_2051 765230d37a1b71c8a3dad7ae42cf30c8 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 47 2.6E-9 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_2051 765230d37a1b71c8a3dad7ae42cf30c8 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 58 2.6E-9 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_2051 765230d37a1b71c8a3dad7ae42cf30c8 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 26 37 2.6E-9 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_2051 765230d37a1b71c8a3dad7ae42cf30c8 298 Gene3D G3DSA:3.40.190.10 106 290 1.9E-54 T 13-10-2018 Astex_2051 765230d37a1b71c8a3dad7ae42cf30c8 298 Gene3D G3DSA:3.40.190.10 166 263 1.9E-54 T 13-10-2018 Astex_2051 765230d37a1b71c8a3dad7ae42cf30c8 298 SUPERFAMILY SSF46785 6 117 3.04E-22 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_2051 765230d37a1b71c8a3dad7ae42cf30c8 298 Gene3D G3DSA:1.10.10.10 10 96 2.1E-22 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1538 9bfb8e6f549fb04961456288490bc8ef 239 Gene3D G3DSA:3.30.2420.10 160 235 5.9E-6 T 13-10-2018 Astex_1538 9bfb8e6f549fb04961456288490bc8ef 239 SUPERFAMILY SSF74653 161 200 8.44E-6 T 13-10-2018 Astex_1538 9bfb8e6f549fb04961456288490bc8ef 239 PRINTS PR01374 Gram-negative bacterial tonB protein signature 67 77 7.9E-5 T 13-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 Astex_1538 9bfb8e6f549fb04961456288490bc8ef 239 PRINTS PR01374 Gram-negative bacterial tonB protein signature 154 175 7.9E-5 T 13-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 Astex_1538 9bfb8e6f549fb04961456288490bc8ef 239 PRINTS PR01374 Gram-negative bacterial tonB protein signature 175 193 7.9E-5 T 13-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 Astex_1538 9bfb8e6f549fb04961456288490bc8ef 239 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 162 222 9.2E-8 T 13-10-2018 IPR037682 TonB, C-terminal GO:0055085 Astex_2755 ba8dbe30fdaa698f8d1615f49f818298 1395 Pfam PF13116 Protein of unknown function 453 615 2.0E-5 T 13-10-2018 IPR025263 Domain of unknown function DUF3971 Astex_2755 ba8dbe30fdaa698f8d1615f49f818298 1395 Pfam PF13502 AsmA-like C-terminal region 1138 1358 6.8E-25 T 13-10-2018 IPR032712 AsmA-like, C-terminal Astex_2483 4c227fbd40998f5eb3a110f24b290107 87 PIRSF PIRSF017854 1 87 2.6E-31 T 13-10-2018 IPR016704 Conjugal transfer, TrbD Astex_2483 4c227fbd40998f5eb3a110f24b290107 87 Pfam PF05101 Type IV secretory pathway, VirB3-like protein 10 84 3.5E-12 T 13-10-2018 IPR007792 Type IV secretion system, VirB3 / TrbD / AvhB Astex_1139 937fe841662992fc87a8771eb6d5e402 304 PIRSF PIRSF000166 6 304 2.0E-106 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 Astex_1139 937fe841662992fc87a8771eb6d5e402 304 Gene3D G3DSA:3.40.1500.10 9 304 1.4E-101 T 13-10-2018 IPR036406 Oxygen-dependent coproporphyrinogen III oxidase superfamily GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 Astex_1139 937fe841662992fc87a8771eb6d5e402 304 PRINTS PR00073 Coprogen oxidase signature 261 288 1.9E-43 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 Astex_1139 937fe841662992fc87a8771eb6d5e402 304 PRINTS PR00073 Coprogen oxidase signature 289 304 1.9E-43 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 Astex_1139 937fe841662992fc87a8771eb6d5e402 304 PRINTS PR00073 Coprogen oxidase signature 189 218 1.9E-43 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 Astex_1139 937fe841662992fc87a8771eb6d5e402 304 PRINTS PR00073 Coprogen oxidase signature 55 71 1.9E-43 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 Astex_1139 937fe841662992fc87a8771eb6d5e402 304 PRINTS PR00073 Coprogen oxidase signature 118 142 1.9E-43 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 Astex_1139 937fe841662992fc87a8771eb6d5e402 304 ProSitePatterns PS01021 Coproporphyrinogen III oxidase signature. 193 217 - T 13-10-2018 IPR018375 Coproporphyrinogen III oxidase, conserved site GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 Astex_1139 937fe841662992fc87a8771eb6d5e402 304 Hamap MF_00333 Oxygen-dependent coproporphyrinogen-III oxidase [hemF]. 17 304 51.785 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 Astex_1139 937fe841662992fc87a8771eb6d5e402 304 Pfam PF01218 Coproporphyrinogen III oxidase 26 303 2.1E-88 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 Astex_1139 937fe841662992fc87a8771eb6d5e402 304 SUPERFAMILY SSF102886 18 304 6.93E-110 T 13-10-2018 IPR036406 Oxygen-dependent coproporphyrinogen III oxidase superfamily GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 Astex_0694 ccb0fdda880fa250993c76aaff647a12 275 Pfam PF03705 CheR methyltransferase, all-alpha domain 10 59 6.2E-8 T 13-10-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal Astex_0694 ccb0fdda880fa250993c76aaff647a12 275 Gene3D G3DSA:3.40.50.150 72 272 7.7E-52 T 13-10-2018 Astex_0694 ccb0fdda880fa250993c76aaff647a12 275 PRINTS PR00996 Glutamate methyltransferase family signature 227 250 2.3E-22 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Astex_0694 ccb0fdda880fa250993c76aaff647a12 275 PRINTS PR00996 Glutamate methyltransferase family signature 208 222 2.3E-22 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Astex_0694 ccb0fdda880fa250993c76aaff647a12 275 PRINTS PR00996 Glutamate methyltransferase family signature 134 150 2.3E-22 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Astex_0694 ccb0fdda880fa250993c76aaff647a12 275 PRINTS PR00996 Glutamate methyltransferase family signature 102 122 2.3E-22 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Astex_0694 ccb0fdda880fa250993c76aaff647a12 275 PRINTS PR00996 Glutamate methyltransferase family signature 66 78 2.3E-22 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Astex_0694 ccb0fdda880fa250993c76aaff647a12 275 SMART SM00138 7 270 1.4E-19 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Astex_0694 ccb0fdda880fa250993c76aaff647a12 275 SUPERFAMILY SSF53335 74 258 8.66E-36 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Astex_0694 ccb0fdda880fa250993c76aaff647a12 275 Pfam PF01739 CheR methyltransferase, SAM binding domain 74 257 6.0E-35 T 13-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal Astex_2796 1919707eaa37de4c5b36fb096208436e 354 PIRSF PIRSF038940 13 353 5.9E-135 T 13-10-2018 IPR026273 Low specificity L-threonine aldolase GO:0004793|GO:0006567 KEGG: 00260+4.1.2.48 Astex_2796 1919707eaa37de4c5b36fb096208436e 354 Gene3D G3DSA:3.40.640.10 25 263 4.1E-122 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Astex_2796 1919707eaa37de4c5b36fb096208436e 354 Pfam PF01212 Beta-eliminating lyase 15 302 9.7E-71 T 13-10-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 Astex_2796 1919707eaa37de4c5b36fb096208436e 354 SUPERFAMILY SSF53383 15 349 3.59E-97 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Astex_2796 1919707eaa37de4c5b36fb096208436e 354 Gene3D G3DSA:3.90.1150.10 18 343 4.1E-122 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Astex_2737 de9a82224cf74cc27860e6624b8c27aa 287 Pfam PF01738 Dienelactone hydrolase family 76 285 1.6E-48 T 13-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 Astex_2737 de9a82224cf74cc27860e6624b8c27aa 287 Gene3D G3DSA:3.40.50.1820 55 286 7.3E-58 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_2737 de9a82224cf74cc27860e6624b8c27aa 287 SUPERFAMILY SSF53474 74 286 6.79E-38 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_2959 e561c993a822bb45945f179207a81640 239 SUPERFAMILY SSF50249 3 66 3.6E-8 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Astex_2959 e561c993a822bb45945f179207a81640 239 ProDom PD202328 DNA REPAIR RECOMBINATION RECO DAMAGE O O RECO-RELATED RECOMBINATIONAL RP549 132 219 2.0E-20 T 13-10-2018 Astex_2959 e561c993a822bb45945f179207a81640 239 SUPERFAMILY SSF57863 81 176 8.89E-7 T 13-10-2018 IPR037278 ARFGAP/RecO-like zinc finger Astex_2959 e561c993a822bb45945f179207a81640 239 TIGRFAM TIGR00613 reco: DNA repair protein RecO 5 220 8.8E-23 T 13-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 Astex_2959 e561c993a822bb45945f179207a81640 239 Gene3D G3DSA:2.40.50.140 3 71 3.1E-8 T 13-10-2018 Astex_2959 e561c993a822bb45945f179207a81640 239 Hamap MF_00201 DNA repair protein RecO [recO]. 1 237 15.432 T 13-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 Astex_2959 e561c993a822bb45945f179207a81640 239 Pfam PF02565 Recombination protein O C terminal 84 223 1.2E-21 T 13-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 Astex_2959 e561c993a822bb45945f179207a81640 239 Pfam PF11967 Recombination protein O N terminal 3 68 2.1E-12 T 13-10-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal Astex_3810 c2b45eb12554adc43d5d9a679001720f 306 Pfam PF13182 Protein of unknown function (DUF4007) 14 297 1.5E-82 T 13-10-2018 IPR025248 Domain of unknown function DUF4007 Astex_1030 5a89a642a50117993f5e640d1174a368 214 Gene3D G3DSA:3.40.50.300 12 213 3.8E-47 T 13-10-2018 Astex_1030 5a89a642a50117993f5e640d1174a368 214 SUPERFAMILY SSF52540 21 207 1.35E-44 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1030 5a89a642a50117993f5e640d1174a368 214 Pfam PF00005 ABC transporter 22 164 4.4E-28 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_1030 5a89a642a50117993f5e640d1174a368 214 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Astex_1030 5a89a642a50117993f5e640d1174a368 214 SMART SM00382 26 212 1.5E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_0644 07aed1fa77caaab8003174f1acd81305 540 SUPERFAMILY SSF75005 2 312 1.86E-98 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Astex_0644 07aed1fa77caaab8003174f1acd81305 540 Pfam PF04616 Glycosyl hydrolases family 43 2 302 2.4E-104 T 13-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 Astex_0644 07aed1fa77caaab8003174f1acd81305 540 SUPERFAMILY SSF49899 331 532 2.89E-61 T 13-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily Astex_0644 07aed1fa77caaab8003174f1acd81305 540 Gene3D G3DSA:2.115.10.20 1 311 1.1E-100 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Astex_0644 07aed1fa77caaab8003174f1acd81305 540 Gene3D G3DSA:2.60.120.200 330 536 2.2E-55 T 13-10-2018 Astex_2100 377aad80ac9446e5afb1f1613456cebb 189 Gene3D G3DSA:3.40.630.30 3 175 1.5E-42 T 13-10-2018 Astex_2100 377aad80ac9446e5afb1f1613456cebb 189 Pfam PF13302 Acetyltransferase (GNAT) domain 9 143 3.2E-17 T 13-10-2018 IPR000182 GNAT domain Astex_2100 377aad80ac9446e5afb1f1613456cebb 189 SUPERFAMILY SSF55729 9 167 4.88E-31 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Astex_2100 377aad80ac9446e5afb1f1613456cebb 189 TIGRFAM TIGR03585 PseH: UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase 10 164 4.7E-49 T 13-10-2018 IPR020036 UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase Astex_3549 04a71225528d135b46b6be49917d0df4 696 Pfam PF16153 Domain of unknown function (DUF4861) 451 695 4.3E-50 T 13-10-2018 IPR032342 Protein of unknown function DUF4861 Astex_3549 04a71225528d135b46b6be49917d0df4 696 Pfam PF07470 Glycosyl Hydrolase Family 88 77 393 1.0E-70 T 13-10-2018 IPR010905 Glycosyl hydrolase, family 88 Astex_3549 04a71225528d135b46b6be49917d0df4 696 Gene3D G3DSA:1.50.10.10 45 397 6.4E-112 T 13-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 Astex_3549 04a71225528d135b46b6be49917d0df4 696 SUPERFAMILY SSF48208 79 396 6.8E-46 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 Astex_0002 1dbf00ae3e3e15f9fe2c9e4178da3cb7 373 SMART SM00480 17 369 1.2E-129 T 13-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 Astex_0002 1dbf00ae3e3e15f9fe2c9e4178da3cb7 373 SUPERFAMILY SSF55979 253 373 5.76E-34 T 13-10-2018 Astex_0002 1dbf00ae3e3e15f9fe2c9e4178da3cb7 373 Gene3D G3DSA:3.10.150.10 129 254 2.9E-33 T 13-10-2018 Astex_0002 1dbf00ae3e3e15f9fe2c9e4178da3cb7 373 PIRSF PIRSF000804 1 373 1.9E-114 T 13-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 Astex_0002 1dbf00ae3e3e15f9fe2c9e4178da3cb7 373 SUPERFAMILY SSF55979 134 251 5.65E-24 T 13-10-2018 Astex_0002 1dbf00ae3e3e15f9fe2c9e4178da3cb7 373 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 121 1.7E-34 T 13-10-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 Astex_0002 1dbf00ae3e3e15f9fe2c9e4178da3cb7 373 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 253 372 2.7E-35 T 13-10-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 Astex_0002 1dbf00ae3e3e15f9fe2c9e4178da3cb7 373 SUPERFAMILY SSF55979 1 119 1.0E-24 T 13-10-2018 Astex_0002 1dbf00ae3e3e15f9fe2c9e4178da3cb7 373 Pfam PF02767 DNA polymerase III beta subunit, central domain 134 250 5.3E-32 T 13-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 Astex_0002 1dbf00ae3e3e15f9fe2c9e4178da3cb7 373 Gene3D G3DSA:3.10.150.10 255 373 5.5E-35 T 13-10-2018 Astex_0002 1dbf00ae3e3e15f9fe2c9e4178da3cb7 373 Gene3D G3DSA:3.10.150.10 1 123 7.7E-39 T 13-10-2018 Astex_0002 1dbf00ae3e3e15f9fe2c9e4178da3cb7 373 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 372 1.9E-86 T 13-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 Astex_1767 71c8d5a15be83dde2a4600558934f763 344 Pfam PF00140 Sigma-70 factor, region 1.2 71 96 2.9E-6 T 13-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Astex_1767 71c8d5a15be83dde2a4600558934f763 344 SUPERFAMILY SSF88946 65 174 1.18E-37 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 Astex_1767 71c8d5a15be83dde2a4600558934f763 344 Gene3D G3DSA:1.20.140.160 186 340 4.8E-19 T 13-10-2018 Astex_1767 71c8d5a15be83dde2a4600558934f763 344 Hamap MF_00961 RNA polymerase sigma factor RpoH [rpoH]. 55 340 51.898 T 13-10-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003700|GO:0006352|GO:0006355|GO:0016987 Astex_1767 71c8d5a15be83dde2a4600558934f763 344 TIGRFAM TIGR02392 rpoH_proteo: alternative sigma factor RpoH 68 339 3.1E-112 T 13-10-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003700|GO:0006352|GO:0006355|GO:0016987 Astex_1767 71c8d5a15be83dde2a4600558934f763 344 Pfam PF04542 Sigma-70 region 2 106 174 5.0E-16 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 Astex_1767 71c8d5a15be83dde2a4600558934f763 344 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 130 143 - T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Astex_1767 71c8d5a15be83dde2a4600558934f763 344 Pfam PF04545 Sigma-70, region 4 285 336 2.8E-17 T 13-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 Astex_1767 71c8d5a15be83dde2a4600558934f763 344 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 102 338 7.7E-32 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 Astex_1767 71c8d5a15be83dde2a4600558934f763 344 SUPERFAMILY SSF88659 248 338 1.18E-21 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Astex_1767 71c8d5a15be83dde2a4600558934f763 344 Gene3D G3DSA:1.20.120.1810 83 173 3.8E-29 T 13-10-2018 Astex_1767 71c8d5a15be83dde2a4600558934f763 344 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 308 334 - T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Astex_1767 71c8d5a15be83dde2a4600558934f763 344 PRINTS PR00046 Major sigma-70 factor signature 289 301 1.5E-21 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Astex_1767 71c8d5a15be83dde2a4600558934f763 344 PRINTS PR00046 Major sigma-70 factor signature 323 334 1.5E-21 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Astex_1767 71c8d5a15be83dde2a4600558934f763 344 PRINTS PR00046 Major sigma-70 factor signature 130 143 1.5E-21 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Astex_1767 71c8d5a15be83dde2a4600558934f763 344 PRINTS PR00046 Major sigma-70 factor signature 154 162 1.5E-21 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Astex_1767 71c8d5a15be83dde2a4600558934f763 344 PRINTS PR00046 Major sigma-70 factor signature 308 323 1.5E-21 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Astex_0137 e3aadf854388d6bc9a5faf8b1c06a87d 294 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 37 208 6.0E-63 T 13-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 Astex_0137 e3aadf854388d6bc9a5faf8b1c06a87d 294 Gene3D G3DSA:3.90.1530.30 49 114 3.3E-26 T 13-10-2018 Astex_0137 e3aadf854388d6bc9a5faf8b1c06a87d 294 Pfam PF02195 ParB-like nuclease domain 37 127 1.5E-28 T 13-10-2018 IPR003115 ParB/Sulfiredoxin Astex_0137 e3aadf854388d6bc9a5faf8b1c06a87d 294 SUPERFAMILY SSF110849 38 174 3.4E-32 T 13-10-2018 IPR036086 ParB/Sulfiredoxin superfamily Astex_0137 e3aadf854388d6bc9a5faf8b1c06a87d 294 Gene3D G3DSA:1.10.10.2830 115 226 4.2E-36 T 13-10-2018 Astex_0137 e3aadf854388d6bc9a5faf8b1c06a87d 294 SMART SM00470 36 128 4.8E-38 T 13-10-2018 IPR003115 ParB/Sulfiredoxin Astex_2700 d95c752c8a7d0ac0947d14028443a312 447 Pfam PF00202 Aminotransferase class-III 33 442 1.7E-58 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Astex_2700 d95c752c8a7d0ac0947d14028443a312 447 PIRSF PIRSF000521 2 447 7.6E-70 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Astex_2700 d95c752c8a7d0ac0947d14028443a312 447 Gene3D G3DSA:3.90.1150.10 11 439 9.0E-96 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Astex_2700 d95c752c8a7d0ac0947d14028443a312 447 Gene3D G3DSA:3.40.640.10 71 350 9.0E-96 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Astex_2700 d95c752c8a7d0ac0947d14028443a312 447 SUPERFAMILY SSF53383 29 445 4.66E-62 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Astex_2205 45f68bed0b81349ba0aa69ab110bc59d 432 Pfam PF01943 Polysaccharide biosynthesis protein 8 257 2.3E-8 T 13-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 Astex_1491 02928e472e26209fa6c7853da3ab53e6 425 SUPERFAMILY SSF56349 73 374 5.42E-29 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 Astex_1491 02928e472e26209fa6c7853da3ab53e6 425 Pfam PF13102 Phage integrase SAM-like domain 93 176 4.9E-5 T 13-10-2018 IPR025269 Phage integrase SAM-like domain Astex_1491 02928e472e26209fa6c7853da3ab53e6 425 Gene3D G3DSA:1.10.150.130 68 187 3.6E-11 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal Astex_1491 02928e472e26209fa6c7853da3ab53e6 425 Gene3D G3DSA:1.10.443.10 188 403 8.1E-14 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 Astex_2088 0e67a33329f171e9cd7f19b2de3fcc9f 388 Pfam PF08331 Domain of unknown function (DUF1730) 69 145 1.1E-21 T 13-10-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 Astex_2088 0e67a33329f171e9cd7f19b2de3fcc9f 388 SUPERFAMILY SSF46548 144 261 1.57E-19 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Astex_2088 0e67a33329f171e9cd7f19b2de3fcc9f 388 Pfam PF13484 4Fe-4S double cluster binding domain 197 261 4.0E-18 T 13-10-2018 Astex_2088 0e67a33329f171e9cd7f19b2de3fcc9f 388 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 20 356 1.0E-124 T 13-10-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 Astex_2088 0e67a33329f171e9cd7f19b2de3fcc9f 388 SUPERFAMILY SSF48371 282 373 2.22E-5 T 13-10-2018 IPR016024 Armadillo-type fold Astex_2088 0e67a33329f171e9cd7f19b2de3fcc9f 388 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 198 209 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Astex_3726 331b3ed29cc06f0699b5bd47f481e6d6 172 Pfam PF10741 Type II secretion system (T2SS), protein M subtype b 84 157 4.7E-5 T 13-10-2018 IPR034756 Type II secretion system (T2SS), protein M subtype b Astex_1004 e1290e59dfbbf26ed0d0a4ee94a0a2cf 174 SUPERFAMILY SSF47413 6 49 3.44E-10 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Astex_1004 e1290e59dfbbf26ed0d0a4ee94a0a2cf 174 Pfam PF01381 Helix-turn-helix 8 44 7.3E-9 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Astex_1004 e1290e59dfbbf26ed0d0a4ee94a0a2cf 174 SMART SM00530 7 61 5.6E-6 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Astex_1004 e1290e59dfbbf26ed0d0a4ee94a0a2cf 174 Gene3D G3DSA:1.10.260.40 4 66 1.6E-10 T 13-10-2018 Astex_1418 28f512193c3476b3bde3f840c3b30c18 87 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 1 85 4.4E-31 T 13-10-2018 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 Astex_1418 28f512193c3476b3bde3f840c3b30c18 87 PIRSF PIRSF004669 1 87 3.6E-27 T 13-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 Astex_1418 28f512193c3476b3bde3f840c3b30c18 87 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 4.7E-20 T 13-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 Astex_1418 28f512193c3476b3bde3f840c3b30c18 87 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 4.7E-20 T 13-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 Astex_1418 28f512193c3476b3bde3f840c3b30c18 87 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 4.7E-20 T 13-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 Astex_1418 28f512193c3476b3bde3f840c3b30c18 87 Pfam PF01313 Bacterial export proteins, family 3 6 77 8.1E-27 T 13-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 Astex_0087 13784b856458498762e99644b468d997 225 Pfam PF01810 LysE type translocator 22 216 3.4E-32 T 13-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 Astex_0087 13784b856458498762e99644b468d997 225 PIRSF PIRSF006324 7 219 2.1E-40 T 13-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 Astex_1240 00b369ef050d647031e4410061e214c5 863 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 2 530 41.556 T 13-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 Astex_1240 00b369ef050d647031e4410061e214c5 863 Gene3D G3DSA:3.30.1360.200 209 347 1.1E-61 T 13-10-2018 Astex_1240 00b369ef050d647031e4410061e214c5 863 SUPERFAMILY SSF82866 648 839 1.44E-38 T 13-10-2018 Astex_1240 00b369ef050d647031e4410061e214c5 863 Pfam PF07549 SecD/SecF GG Motif 586 601 0.018 T 13-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site Astex_1240 00b369ef050d647031e4410061e214c5 863 Pfam PF07549 SecD/SecF GG Motif 38 63 8.0E-9 T 13-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site Astex_1240 00b369ef050d647031e4410061e214c5 863 Gene3D G3DSA:1.20.1640.10 672 849 2.0E-7 T 13-10-2018 Astex_1240 00b369ef050d647031e4410061e214c5 863 Gene3D G3DSA:1.20.1640.10 365 531 3.0E-6 T 13-10-2018 Astex_1240 00b369ef050d647031e4410061e214c5 863 Gene3D G3DSA:3.30.70.3400 153 353 1.1E-61 T 13-10-2018 Astex_1240 00b369ef050d647031e4410061e214c5 863 Gene3D G3DSA:3.30.70.3400 46 117 5.2E-6 T 13-10-2018 Astex_1240 00b369ef050d647031e4410061e214c5 863 Pfam PF02355 Protein export membrane protein 655 839 3.9E-68 T 13-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial Astex_1240 00b369ef050d647031e4410061e214c5 863 Pfam PF02355 Protein export membrane protein 351 522 3.0E-18 T 13-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial Astex_1240 00b369ef050d647031e4410061e214c5 863 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 586 831 1.3E-81 T 13-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 Astex_1240 00b369ef050d647031e4410061e214c5 863 Gene3D G3DSA:1.20.1640.10 532 585 3.0E-6 T 13-10-2018 Astex_1240 00b369ef050d647031e4410061e214c5 863 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 552 842 28.521 T 13-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 Astex_1240 00b369ef050d647031e4410061e214c5 863 PRINTS PR01755 Bacterial translocase SecF protein signature 585 600 1.8E-30 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial Astex_1240 00b369ef050d647031e4410061e214c5 863 PRINTS PR01755 Bacterial translocase SecF protein signature 747 765 1.8E-30 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial Astex_1240 00b369ef050d647031e4410061e214c5 863 PRINTS PR01755 Bacterial translocase SecF protein signature 699 713 1.8E-30 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial Astex_1240 00b369ef050d647031e4410061e214c5 863 PRINTS PR01755 Bacterial translocase SecF protein signature 779 794 1.8E-30 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial Astex_1240 00b369ef050d647031e4410061e214c5 863 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 46 517 1.9E-130 T 13-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 Astex_1240 00b369ef050d647031e4410061e214c5 863 Gene3D G3DSA:3.30.70.1430 586 611 3.0E-6 T 13-10-2018 Astex_1240 00b369ef050d647031e4410061e214c5 863 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 667 828 2.5E-52 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial Astex_1240 00b369ef050d647031e4410061e214c5 863 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 279 510 2.3E-71 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial Astex_1240 00b369ef050d647031e4410061e214c5 863 SUPERFAMILY SSF82866 326 526 1.31E-41 T 13-10-2018 Astex_2192 6d06c344e32e2f30dbb9637183033032 355 Pfam PF01757 Acyltransferase family 7 329 3.0E-21 T 13-10-2018 IPR002656 Acyltransferase 3 GO:0016747 Astex_2871 0b1fb2124326be492714fa899b6bf59d 778 SUPERFAMILY SSF47384 527 602 1.28E-11 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Astex_2871 0b1fb2124326be492714fa899b6bf59d 778 SUPERFAMILY SSF158472 357 406 8.89E-9 T 13-10-2018 Astex_2871 0b1fb2124326be492714fa899b6bf59d 778 Gene3D G3DSA:1.10.287.130 524 601 1.1E-11 T 13-10-2018 Astex_2871 0b1fb2124326be492714fa899b6bf59d 778 PIRSF PIRSF037532 38 764 1.4E-206 T 13-10-2018 IPR017232 Signal transduction histidine kinase, nitrogen fixation and metabolism regulator Astex_2871 0b1fb2124326be492714fa899b6bf59d 778 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 647 759 8.9E-15 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_2871 0b1fb2124326be492714fa899b6bf59d 778 SUPERFAMILY SSF55785 411 523 4.0E-9 T 13-10-2018 IPR035965 PAS domain superfamily Astex_2871 0b1fb2124326be492714fa899b6bf59d 778 Gene3D G3DSA:3.30.450.20 413 523 1.1E-12 T 13-10-2018 Astex_2871 0b1fb2124326be492714fa899b6bf59d 778 SMART SM00387 644 760 3.8E-26 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_2871 0b1fb2124326be492714fa899b6bf59d 778 Pfam PF00672 HAMP domain 357 405 1.3E-6 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Astex_2871 0b1fb2124326be492714fa899b6bf59d 778 Pfam PF00989 PAS fold 421 522 3.4E-6 T 13-10-2018 IPR013767 PAS fold GO:0006355 Astex_2871 0b1fb2124326be492714fa899b6bf59d 778 SMART SM00388 533 604 1.3E-9 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_2871 0b1fb2124326be492714fa899b6bf59d 778 Gene3D G3DSA:1.20.1480.50 313 412 1.5E-10 T 13-10-2018 Astex_2871 0b1fb2124326be492714fa899b6bf59d 778 PRINTS PR00344 Bacterial sensor protein C-terminal signature 719 737 1.6E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_2871 0b1fb2124326be492714fa899b6bf59d 778 PRINTS PR00344 Bacterial sensor protein C-terminal signature 690 704 1.6E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_2871 0b1fb2124326be492714fa899b6bf59d 778 PRINTS PR00344 Bacterial sensor protein C-terminal signature 708 718 1.6E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_2871 0b1fb2124326be492714fa899b6bf59d 778 SMART SM00304 356 409 1.7E-8 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Astex_2871 0b1fb2124326be492714fa899b6bf59d 778 Gene3D G3DSA:3.30.565.10 608 768 5.1E-27 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_2871 0b1fb2124326be492714fa899b6bf59d 778 SUPERFAMILY SSF55874 608 760 1.02E-27 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_2871 0b1fb2124326be492714fa899b6bf59d 778 Pfam PF00512 His Kinase A (phospho-acceptor) domain 536 601 2.7E-8 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_0435 21cbd16aa84f675d2d28138aca72c314 277 Pfam PF13374 Tetratricopeptide repeat 218 241 0.0035 T 13-10-2018 Astex_0435 21cbd16aa84f675d2d28138aca72c314 277 SMART SM00028 80 113 140.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Astex_0435 21cbd16aa84f675d2d28138aca72c314 277 SMART SM00028 216 249 360.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Astex_0435 21cbd16aa84f675d2d28138aca72c314 277 SMART SM00028 148 181 1.5E-5 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Astex_0435 21cbd16aa84f675d2d28138aca72c314 277 SMART SM00028 114 147 450.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Astex_0435 21cbd16aa84f675d2d28138aca72c314 277 SMART SM00028 182 215 200.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Astex_0435 21cbd16aa84f675d2d28138aca72c314 277 Gene3D G3DSA:1.25.40.10 63 259 1.1E-28 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_0435 21cbd16aa84f675d2d28138aca72c314 277 PIRSF PIRSF035836 4 275 2.6E-65 T 13-10-2018 IPR014596 Uncharacterised conserved protein UCP035836 Astex_0435 21cbd16aa84f675d2d28138aca72c314 277 Pfam PF07719 Tetratricopeptide repeat 149 181 1.6E-5 T 13-10-2018 IPR013105 Tetratricopeptide repeat 2 Astex_0435 21cbd16aa84f675d2d28138aca72c314 277 SUPERFAMILY SSF48452 77 241 1.39E-23 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_0637 3fe25e1e3bb4f07684ff64947b428c38 342 Gene3D G3DSA:3.20.20.210 1 342 2.1E-130 T 13-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 Astex_0637 3fe25e1e3bb4f07684ff64947b428c38 342 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 6 328 2.9E-35 T 13-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 Astex_0637 3fe25e1e3bb4f07684ff64947b428c38 342 SUPERFAMILY SSF51726 8 341 1.96E-66 T 13-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 Astex_0637 3fe25e1e3bb4f07684ff64947b428c38 342 PIRSF PIRSF005632 1 342 7.8E-188 T 13-10-2018 IPR016456 Predicted cobalamin-independent methionine synthase, catalytic subunit Astex_1973 4281399e3c8633b8ecb54df4a1ec6cd6 265 Gene3D G3DSA:3.40.50.1110 29 265 2.5E-47 T 13-10-2018 IPR036514 SGNH hydrolase superfamily Astex_1973 4281399e3c8633b8ecb54df4a1ec6cd6 265 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 35 179 3.8E-8 T 13-10-2018 IPR013830 SGNH hydrolase-type esterase domain Astex_1973 4281399e3c8633b8ecb54df4a1ec6cd6 265 SUPERFAMILY SSF52266 30 257 7.0E-35 T 13-10-2018 Astex_3716 6cb5b4659ba590b9ab377a8f97aab079 1550 Pfam PF05593 RHS Repeat 841 871 8.0E-5 T 13-10-2018 IPR031325 RHS repeat Astex_3716 6cb5b4659ba590b9ab377a8f97aab079 1550 SMART SM00306 1317 1417 3.3E-13 T 13-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 Astex_3716 6cb5b4659ba590b9ab377a8f97aab079 1550 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 1435 1458 0.0025 T 13-10-2018 IPR030934 Intein C-terminal splicing region Astex_3716 6cb5b4659ba590b9ab377a8f97aab079 1550 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1115 1188 7.6E-23 T 13-10-2018 IPR022385 Rhs repeat-associated core GO:0097264 Astex_3716 6cb5b4659ba590b9ab377a8f97aab079 1550 Gene3D G3DSA:3.90.930.1 254 413 2.3E-8 T 13-10-2018 Astex_3716 6cb5b4659ba590b9ab377a8f97aab079 1550 PRINTS PR00394 RHS protein signature 1132 1152 4.6E-5 T 13-10-2018 IPR001826 RHS protein Astex_3716 6cb5b4659ba590b9ab377a8f97aab079 1550 PRINTS PR00394 RHS protein signature 1155 1174 4.6E-5 T 13-10-2018 IPR001826 RHS protein Astex_3716 6cb5b4659ba590b9ab377a8f97aab079 1550 Pfam PF07591 Pretoxin HINT domain 1326 1457 6.0E-20 T 13-10-2018 Astex_3716 6cb5b4659ba590b9ab377a8f97aab079 1550 SUPERFAMILY SSF51294 1319 1456 3.73E-21 T 13-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 Astex_3716 6cb5b4659ba590b9ab377a8f97aab079 1550 Gene3D G3DSA:2.170.16.10 1316 1457 3.3E-32 T 13-10-2018 Astex_3716 6cb5b4659ba590b9ab377a8f97aab079 1550 Gene3D G3DSA:2.180.10.10 958 1188 1.6E-23 T 13-10-2018 Astex_3716 6cb5b4659ba590b9ab377a8f97aab079 1550 Gene3D G3DSA:2.180.10.10 842 957 4.7E-6 T 13-10-2018 Astex_2218 93c0f345ff4348fde4d8c05950520d2d 291 Gene3D G3DSA:3.90.550.10 11 213 6.1E-16 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_2218 93c0f345ff4348fde4d8c05950520d2d 291 Pfam PF00535 Glycosyl transferase family 2 60 115 3.0E-5 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 Astex_2218 93c0f345ff4348fde4d8c05950520d2d 291 SUPERFAMILY SSF53448 6 212 2.25E-20 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_2194 7747966edb50c6e7bcb5f9ed28315495 537 Pfam PF13007 Transposase C of IS166 homeodomain 52 128 1.1E-11 T 13-10-2018 IPR024463 Transposase TnpC, homeodomain Astex_2194 7747966edb50c6e7bcb5f9ed28315495 537 Pfam PF03050 Transposase IS66 family 194 483 4.0E-91 T 13-10-2018 IPR004291 Transposase, IS66 Astex_2194 7747966edb50c6e7bcb5f9ed28315495 537 Pfam PF13005 zinc-finger binding domain of transposase IS66 142 174 5.3E-7 T 13-10-2018 IPR024474 Zinc-finger binding domain of transposase IS66 Astex_2194 7747966edb50c6e7bcb5f9ed28315495 537 Pfam PF13817 IS66 C-terminal element 490 528 5.6E-18 T 13-10-2018 IPR039552 Transposase IS66, C-terminal Astex_3051 7747966edb50c6e7bcb5f9ed28315495 537 Pfam PF13007 Transposase C of IS166 homeodomain 52 128 1.1E-11 T 13-10-2018 IPR024463 Transposase TnpC, homeodomain Astex_3051 7747966edb50c6e7bcb5f9ed28315495 537 Pfam PF03050 Transposase IS66 family 194 483 4.0E-91 T 13-10-2018 IPR004291 Transposase, IS66 Astex_3051 7747966edb50c6e7bcb5f9ed28315495 537 Pfam PF13005 zinc-finger binding domain of transposase IS66 142 174 5.3E-7 T 13-10-2018 IPR024474 Zinc-finger binding domain of transposase IS66 Astex_3051 7747966edb50c6e7bcb5f9ed28315495 537 Pfam PF13817 IS66 C-terminal element 490 528 5.6E-18 T 13-10-2018 IPR039552 Transposase IS66, C-terminal Astex_0910 c469cc3a295ad9b95279b29acae29849 376 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 13 364 33.728 T 13-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 Astex_0910 c469cc3a295ad9b95279b29acae29849 376 PIRSF PIRSF004640 7 370 2.0E-147 T 13-10-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 Astex_0910 c469cc3a295ad9b95279b29acae29849 376 SUPERFAMILY SSF51604 28 144 2.12E-10 T 13-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily Astex_0910 c469cc3a295ad9b95279b29acae29849 376 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 15 359 5.6E-143 T 13-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 Astex_0910 c469cc3a295ad9b95279b29acae29849 376 SUPERFAMILY SSF56014 271 362 7.71E-14 T 13-10-2018 Astex_0910 c469cc3a295ad9b95279b29acae29849 376 Gene3D G3DSA:3.20.20.20 4 267 2.1E-106 T 13-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Astex_0910 c469cc3a295ad9b95279b29acae29849 376 Pfam PF04551 GcpE protein 19 360 8.0E-131 T 13-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 Astex_0910 c469cc3a295ad9b95279b29acae29849 376 Gene3D G3DSA:3.30.413.10 268 368 1.6E-23 T 13-10-2018 Astex_2719 4f16515cde84c9c7ac226f16f1db8ba4 301 SUPERFAMILY SSF53067 115 282 4.35E-39 T 13-10-2018 Astex_2719 4f16515cde84c9c7ac226f16f1db8ba4 301 Gene3D G3DSA:3.30.420.40 4 114 1.4E-74 T 13-10-2018 Astex_2719 4f16515cde84c9c7ac226f16f1db8ba4 301 SUPERFAMILY SSF53067 1 112 3.67E-24 T 13-10-2018 Astex_2719 4f16515cde84c9c7ac226f16f1db8ba4 301 Gene3D G3DSA:3.30.420.40 115 261 1.4E-74 T 13-10-2018 Astex_2719 4f16515cde84c9c7ac226f16f1db8ba4 301 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 6 255 1.0E-34 T 13-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 Astex_1472 26eaae07427533738ef46304cf188f00 1074 Gene3D G3DSA:3.40.50.300 374 534 1.3E-62 T 13-10-2018 Astex_1472 26eaae07427533738ef46304cf188f00 1074 Gene3D G3DSA:2.30.30.940 617 695 1.3E-62 T 13-10-2018 Astex_1472 26eaae07427533738ef46304cf188f00 1074 SUPERFAMILY SSF52540 496 744 8.32E-34 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1472 26eaae07427533738ef46304cf188f00 1074 TIGRFAM TIGR02768 TraA_Ti: Ti-type conjugative transfer relaxase TraA 1 794 6.1E-291 T 13-10-2018 IPR014136 Ti-type conjugative transfer relaxase TraA Astex_1472 26eaae07427533738ef46304cf188f00 1074 Gene3D G3DSA:3.30.930.30 2 208 7.6E-73 T 13-10-2018 Astex_1472 26eaae07427533738ef46304cf188f00 1074 Gene3D G3DSA:3.40.50.300 535 744 1.3E-62 T 13-10-2018 Astex_1472 26eaae07427533738ef46304cf188f00 1074 Pfam PF03389 MobA/MobL family 17 230 1.1E-71 T 13-10-2018 IPR005053 MobA/MobL protein Astex_1472 26eaae07427533738ef46304cf188f00 1074 Pfam PF13604 AAA domain 383 569 1.8E-55 T 13-10-2018 Astex_1472 26eaae07427533738ef46304cf188f00 1074 SUPERFAMILY SSF52540 364 554 1.56E-22 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0465 ce40ac42ef14ce36915002fadb39e4f5 560 Gene3D G3DSA:1.10.287.950 269 559 3.9E-52 T 13-10-2018 Astex_0465 ce40ac42ef14ce36915002fadb39e4f5 560 Pfam PF12729 Four helix bundle sensory module for signal transduction 4 178 2.9E-24 T 13-10-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain Astex_0465 ce40ac42ef14ce36915002fadb39e4f5 560 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 361 520 1.7E-29 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_0465 ce40ac42ef14ce36915002fadb39e4f5 560 SMART SM00304 210 263 1.6E-7 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Astex_0465 ce40ac42ef14ce36915002fadb39e4f5 560 SMART SM00283 300 554 1.0E-40 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_0465 ce40ac42ef14ce36915002fadb39e4f5 560 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 2 27 1.2E-19 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_0465 ce40ac42ef14ce36915002fadb39e4f5 560 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 398 425 1.2E-19 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_0465 ce40ac42ef14ce36915002fadb39e4f5 560 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 427 456 1.2E-19 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_0465 ce40ac42ef14ce36915002fadb39e4f5 560 Gene3D G3DSA:1.20.1480.50 170 268 1.1E-13 T 13-10-2018 Astex_0465 ce40ac42ef14ce36915002fadb39e4f5 560 SUPERFAMILY SSF58104 241 553 2.35E-60 T 13-10-2018 Astex_0109 fa666f52968a48b289d4f38e4fa32364 180 SUPERFAMILY SSF50346 96 164 1.96E-13 T 13-10-2018 IPR011033 PRC-barrel-like superfamily Astex_0109 fa666f52968a48b289d4f38e4fa32364 180 Gene3D G3DSA:2.40.30.60 3 89 2.5E-18 T 13-10-2018 IPR036976 RimM, N-terminal domain superfamily GO:0006364 Astex_0109 fa666f52968a48b289d4f38e4fa32364 180 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 5 165 5.9E-36 T 13-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 Astex_0109 fa666f52968a48b289d4f38e4fa32364 180 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 4 166 21.845 T 13-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 Astex_0109 fa666f52968a48b289d4f38e4fa32364 180 SUPERFAMILY SSF50447 3 89 1.09E-16 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Astex_0109 fa666f52968a48b289d4f38e4fa32364 180 Gene3D G3DSA:2.30.30.240 92 170 1.7E-8 T 13-10-2018 Astex_0109 fa666f52968a48b289d4f38e4fa32364 180 Pfam PF05239 PRC-barrel domain 93 166 3.2E-8 T 13-10-2018 IPR027275 PRC-barrel domain Astex_0109 fa666f52968a48b289d4f38e4fa32364 180 Pfam PF01782 RimM N-terminal domain 7 86 1.0E-17 T 13-10-2018 IPR002676 RimM, N-terminal GO:0006364 Astex_3219 8789065840458c7c8b842439a0758e09 682 Pfam PF02449 Beta-galactosidase 43 401 8.4E-60 T 13-10-2018 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_3219 8789065840458c7c8b842439a0758e09 682 Pfam PF08532 Beta-galactosidase trimerisation domain 414 621 3.8E-34 T 13-10-2018 IPR013738 Beta-galactosidase trimerisation GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_3219 8789065840458c7c8b842439a0758e09 682 SUPERFAMILY SSF51445 40 402 6.17E-59 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_3219 8789065840458c7c8b842439a0758e09 682 SUPERFAMILY SSF52317 412 621 1.43E-31 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Astex_3219 8789065840458c7c8b842439a0758e09 682 Gene3D G3DSA:3.20.20.80 23 407 6.0E-87 T 13-10-2018 Astex_3219 8789065840458c7c8b842439a0758e09 682 Gene3D G3DSA:3.40.50.880 411 624 6.8E-46 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Astex_2889 6590420f0eac87835533b67a2f5f9836 257 Gene3D G3DSA:3.90.550.10 1 227 4.2E-23 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_2889 6590420f0eac87835533b67a2f5f9836 257 Pfam PF00535 Glycosyl transferase family 2 8 131 3.1E-16 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 Astex_2889 6590420f0eac87835533b67a2f5f9836 257 SUPERFAMILY SSF53448 5 143 2.34E-25 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_2908 506d9b7bac0fc6abc4d768239e3b1a95 203 SUPERFAMILY SSF46609 1 86 3.4E-34 T 13-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Astex_2908 506d9b7bac0fc6abc4d768239e3b1a95 203 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 160 167 - T 13-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Astex_2908 506d9b7bac0fc6abc4d768239e3b1a95 203 Gene3D G3DSA:1.10.287.990 20 84 1.3E-23 T 13-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Astex_2908 506d9b7bac0fc6abc4d768239e3b1a95 203 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 92 193 5.5E-38 T 13-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Astex_2908 506d9b7bac0fc6abc4d768239e3b1a95 203 PRINTS PR01703 Manganese superoxide dismutase signature 158 170 1.2E-23 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Astex_2908 506d9b7bac0fc6abc4d768239e3b1a95 203 PRINTS PR01703 Manganese superoxide dismutase signature 121 129 1.2E-23 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Astex_2908 506d9b7bac0fc6abc4d768239e3b1a95 203 PRINTS PR01703 Manganese superoxide dismutase signature 68 81 1.2E-23 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Astex_2908 506d9b7bac0fc6abc4d768239e3b1a95 203 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 1.2E-23 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Astex_2908 506d9b7bac0fc6abc4d768239e3b1a95 203 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 1.2E-23 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Astex_2908 506d9b7bac0fc6abc4d768239e3b1a95 203 PIRSF PIRSF000349 1 200 4.7E-84 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Astex_2908 506d9b7bac0fc6abc4d768239e3b1a95 203 Gene3D G3DSA:2.40.500.20 86 200 1.8E-41 T 13-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Astex_2908 506d9b7bac0fc6abc4d768239e3b1a95 203 SUPERFAMILY SSF54719 87 197 1.44E-42 T 13-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Astex_2908 506d9b7bac0fc6abc4d768239e3b1a95 203 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 85 2.6E-32 T 13-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Astex_3448 7399e3d13a4eb2ce916df35754a96a91 383 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 77 288 4.9E-23 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain Astex_3448 7399e3d13a4eb2ce916df35754a96a91 383 SUPERFAMILY SSF111369 68 294 2.35E-30 T 13-10-2018 Astex_3448 7399e3d13a4eb2ce916df35754a96a91 383 Gene3D G3DSA:1.10.287.470 115 183 8.9E-69 T 13-10-2018 Astex_3448 7399e3d13a4eb2ce916df35754a96a91 383 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 65 368 8.8E-72 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 Astex_3448 7399e3d13a4eb2ce916df35754a96a91 383 Gene3D G3DSA:2.40.30.170 62 294 8.9E-69 T 13-10-2018 Astex_3448 7399e3d13a4eb2ce916df35754a96a91 383 Gene3D G3DSA:2.40.50.100 76 217 8.9E-69 T 13-10-2018 Astex_3448 7399e3d13a4eb2ce916df35754a96a91 383 Gene3D G3DSA:2.40.420.20 57 353 8.9E-69 T 13-10-2018 Astex_3655 e92838a2778f1b7eb06c2b8802787933 139 Pfam PF01850 PIN domain 4 123 3.9E-17 T 13-10-2018 IPR002716 PIN domain Astex_3655 e92838a2778f1b7eb06c2b8802787933 139 Gene3D G3DSA:3.40.50.1010 1 131 3.2E-38 T 13-10-2018 Astex_3655 e92838a2778f1b7eb06c2b8802787933 139 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 4 130 13.076 T 13-10-2018 IPR022907 VapC family GO:0004540 Astex_3655 e92838a2778f1b7eb06c2b8802787933 139 SUPERFAMILY SSF88723 1 132 3.92E-34 T 13-10-2018 IPR029060 PIN-like domain superfamily Astex_3040 b0a7a2ecec61bb2ba13e0cf402aa263f 283 SUPERFAMILY SSF52172 13 139 2.85E-16 T 13-10-2018 IPR011006 CheY-like superfamily Astex_3040 b0a7a2ecec61bb2ba13e0cf402aa263f 283 Gene3D G3DSA:3.40.50.2300 12 140 1.0E-14 T 13-10-2018 Astex_3040 b0a7a2ecec61bb2ba13e0cf402aa263f 283 Gene3D G3DSA:3.40.50.2300 141 278 4.0E-18 T 13-10-2018 Astex_3040 b0a7a2ecec61bb2ba13e0cf402aa263f 283 Pfam PF00072 Response regulator receiver domain 14 125 1.0E-7 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_3040 b0a7a2ecec61bb2ba13e0cf402aa263f 283 Pfam PF00072 Response regulator receiver domain 144 258 7.5E-12 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_3040 b0a7a2ecec61bb2ba13e0cf402aa263f 283 SMART SM00448 12 128 0.002 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_3040 b0a7a2ecec61bb2ba13e0cf402aa263f 283 SMART SM00448 142 258 1.7E-9 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_3040 b0a7a2ecec61bb2ba13e0cf402aa263f 283 SUPERFAMILY SSF52172 141 271 5.69E-20 T 13-10-2018 IPR011006 CheY-like superfamily Astex_1311 d6b1b8be26b500fc8f7ddf59ce239775 768 SUPERFAMILY SSF48208 279 748 2.86E-75 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 Astex_1311 d6b1b8be26b500fc8f7ddf59ce239775 768 Gene3D G3DSA:1.50.10.10 318 693 2.4E-98 T 13-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 Astex_1311 d6b1b8be26b500fc8f7ddf59ce239775 768 Gene3D G3DSA:2.70.98.40 67 307 4.7E-30 T 13-10-2018 IPR037018 Glycoside hydrolase family 65, N-terminal domain superfamily Astex_1311 d6b1b8be26b500fc8f7ddf59ce239775 768 Pfam PF17167 Glycosyl hydrolase 36 superfamily, catalytic domain 312 699 9.7E-54 T 13-10-2018 IPR033432 Glycosyl hydrolase 36, catalytic domain Astex_1311 d6b1b8be26b500fc8f7ddf59ce239775 768 SUPERFAMILY SSF74650 13 274 1.48E-47 T 13-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 Astex_1311 d6b1b8be26b500fc8f7ddf59ce239775 768 Gene3D G3DSA:2.60.420.10 694 768 1.3E-13 T 13-10-2018 Astex_1311 d6b1b8be26b500fc8f7ddf59ce239775 768 Pfam PF06165 Glycosyltransferase family 36 75 272 5.4E-21 T 13-10-2018 IPR010383 Glycosyl hydrolase 94 Astex_1005 1537abbc6bf433d152f8cd2ddf5b8592 327 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 96 327 6.7E-60 T 13-10-2018 Astex_1005 1537abbc6bf433d152f8cd2ddf5b8592 327 SUPERFAMILY SSF51735 86 327 2.87E-78 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_1005 1537abbc6bf433d152f8cd2ddf5b8592 327 Gene3D G3DSA:3.40.50.720 45 327 1.2E-84 T 13-10-2018 Astex_1005 1537abbc6bf433d152f8cd2ddf5b8592 327 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 235 254 1.8E-36 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1005 1537abbc6bf433d152f8cd2ddf5b8592 327 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 174 1.8E-36 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1005 1537abbc6bf433d152f8cd2ddf5b8592 327 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 290 310 1.8E-36 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1005 1537abbc6bf433d152f8cd2ddf5b8592 327 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 225 1.8E-36 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1005 1537abbc6bf433d152f8cd2ddf5b8592 327 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 256 273 1.8E-36 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1005 1537abbc6bf433d152f8cd2ddf5b8592 327 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 105 1.8E-36 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1005 1537abbc6bf433d152f8cd2ddf5b8592 327 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 222 250 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Astex_1005 1537abbc6bf433d152f8cd2ddf5b8592 327 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 174 1.9E-7 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1005 1537abbc6bf433d152f8cd2ddf5b8592 327 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 215 223 1.9E-7 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1005 1537abbc6bf433d152f8cd2ddf5b8592 327 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 235 254 1.9E-7 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1820 52c6a3456304fedab83b053418fa1dfb 793 SUPERFAMILY SSF50249 38 196 4.9E-37 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Astex_1820 52c6a3456304fedab83b053418fa1dfb 793 Gene3D G3DSA:3.50.40.10 199 392 1.2E-60 T 13-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 Astex_1820 52c6a3456304fedab83b053418fa1dfb 793 SMART SM00873 210 383 4.3E-72 T 13-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 Astex_1820 52c6a3456304fedab83b053418fa1dfb 793 Gene3D G3DSA:2.40.50.140 38 154 4.4E-56 T 13-10-2018 Astex_1820 52c6a3456304fedab83b053418fa1dfb 793 Pfam PF01588 Putative tRNA binding domain 46 145 3.5E-20 T 13-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 Astex_1820 52c6a3456304fedab83b053418fa1dfb 793 SMART SM00896 700 792 6.0E-32 T 13-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 Astex_1820 52c6a3456304fedab83b053418fa1dfb 793 Pfam PF03484 tRNA synthetase B5 domain 403 466 2.3E-17 T 13-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 Astex_1820 52c6a3456304fedab83b053418fa1dfb 793 Gene3D G3DSA:3.30.70.380 705 792 1.0E-21 T 13-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 Astex_1820 52c6a3456304fedab83b053418fa1dfb 793 Gene3D G3DSA:3.30.56.10 400 471 1.3E-20 T 13-10-2018 Astex_1820 52c6a3456304fedab83b053418fa1dfb 793 SUPERFAMILY SSF56037 198 394 3.14E-61 T 13-10-2018 Astex_1820 52c6a3456304fedab83b053418fa1dfb 793 Pfam PF03147 Ferredoxin-fold anticodon binding domain 704 792 1.3E-20 T 13-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 Astex_1820 52c6a3456304fedab83b053418fa1dfb 793 SUPERFAMILY SSF54991 698 792 1.7E-21 T 13-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 Astex_1820 52c6a3456304fedab83b053418fa1dfb 793 Pfam PF03483 B3/4 domain 210 383 2.0E-54 T 13-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 Astex_1820 52c6a3456304fedab83b053418fa1dfb 793 SMART SM00874 399 466 1.0E-24 T 13-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 Astex_1820 52c6a3456304fedab83b053418fa1dfb 793 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 787 38.756 T 13-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 Astex_1820 52c6a3456304fedab83b053418fa1dfb 793 Gene3D G3DSA:3.30.56.10 1 180 4.4E-56 T 13-10-2018 Astex_1820 52c6a3456304fedab83b053418fa1dfb 793 Gene3D G3DSA:3.30.930.10 484 685 2.8E-43 T 13-10-2018 Astex_1820 52c6a3456304fedab83b053418fa1dfb 793 SUPERFAMILY SSF55681 462 684 7.95E-41 T 13-10-2018 Astex_1820 52c6a3456304fedab83b053418fa1dfb 793 SUPERFAMILY SSF46955 402 470 4.3E-15 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily Astex_1820 52c6a3456304fedab83b053418fa1dfb 793 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 792 5.5E-189 T 13-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 Astex_1303 f3ae5c17ccb151b8f9987e1159960a72 499 Gene3D G3DSA:3.40.605.10 23 459 2.9E-145 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 Astex_1303 f3ae5c17ccb151b8f9987e1159960a72 499 Pfam PF00171 Aldehyde dehydrogenase family 21 478 1.3E-136 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 Astex_1303 f3ae5c17ccb151b8f9987e1159960a72 499 Gene3D G3DSA:3.40.309.10 249 451 2.9E-145 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 Astex_1303 f3ae5c17ccb151b8f9987e1159960a72 499 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 5 482 4.7E-200 T 13-10-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00640+1.2.1.27|MetaCyc: PWY-5642|Reactome: R-HSA-70895 Astex_1303 f3ae5c17ccb151b8f9987e1159960a72 499 SUPERFAMILY SSF53720 2 483 3.14E-147 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 Astex_0402 3f4a9f008437e7f2f686ac5ea46064e0 89 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 82 1.5E-39 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0402 3f4a9f008437e7f2f686ac5ea46064e0 89 PRINTS PR00063 Ribosomal protein L27 signature 29 53 7.1E-36 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0402 3f4a9f008437e7f2f686ac5ea46064e0 89 PRINTS PR00063 Ribosomal protein L27 signature 4 28 7.1E-36 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0402 3f4a9f008437e7f2f686ac5ea46064e0 89 PRINTS PR00063 Ribosomal protein L27 signature 54 78 7.1E-36 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0402 3f4a9f008437e7f2f686ac5ea46064e0 89 SUPERFAMILY SSF110324 2 83 2.69E-35 T 13-10-2018 Astex_0402 3f4a9f008437e7f2f686ac5ea46064e0 89 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 85 7.0E-18 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0402 3f4a9f008437e7f2f686ac5ea46064e0 89 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 84 28.659 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0402 3f4a9f008437e7f2f686ac5ea46064e0 89 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 13-10-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_0402 3f4a9f008437e7f2f686ac5ea46064e0 89 Pfam PF01016 Ribosomal L27 protein 2 81 6.4E-39 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0402 3f4a9f008437e7f2f686ac5ea46064e0 89 Gene3D G3DSA:2.40.50.100 20 85 8.1E-31 T 13-10-2018 Astex_2011 3a956b9b7cf9a32f7106d74085ba9f52 126 SUPERFAMILY SSF46458 4 125 3.7E-30 T 13-10-2018 IPR009050 Globin-like superfamily Astex_2011 3a956b9b7cf9a32f7106d74085ba9f52 126 Gene3D G3DSA:1.10.490.10 1 126 3.2E-40 T 13-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 Astex_2011 3a956b9b7cf9a32f7106d74085ba9f52 126 Pfam PF01152 Bacterial-like globin 4 124 5.3E-42 T 13-10-2018 IPR001486 Truncated hemoglobin GO:0019825 Astex_3343 cd7d6421a18b645e05149afe6d67d651 67 Gene3D G3DSA:2.40.50.140 2 66 5.9E-25 T 13-10-2018 Astex_3343 cd7d6421a18b645e05149afe6d67d651 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 13-10-2018 IPR019844 Cold-shock conserved site Astex_3343 cd7d6421a18b645e05149afe6d67d651 67 PIRSF PIRSF002599 1 67 2.6E-21 T 13-10-2018 IPR012156 Cold shock, CspA GO:0003676 Astex_3343 cd7d6421a18b645e05149afe6d67d651 67 SUPERFAMILY SSF50249 1 65 1.2E-22 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Astex_3343 cd7d6421a18b645e05149afe6d67d651 67 PRINTS PR00050 Cold shock protein signature 4 19 3.1E-11 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Astex_3343 cd7d6421a18b645e05149afe6d67d651 67 PRINTS PR00050 Cold shock protein signature 40 58 3.1E-11 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Astex_3343 cd7d6421a18b645e05149afe6d67d651 67 PRINTS PR00050 Cold shock protein signature 25 34 3.1E-11 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Astex_3343 cd7d6421a18b645e05149afe6d67d651 67 SMART SM00357 3 67 1.2E-21 T 13-10-2018 IPR011129 Cold shock domain GO:0003676 Astex_3343 cd7d6421a18b645e05149afe6d67d651 67 Pfam PF00313 'Cold-shock' DNA-binding domain 4 65 1.5E-23 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Astex_2215 5c6fe9fe30bdd60e6cfca9a1afb120bf 350 Pfam PF00534 Glycosyl transferases group 1 177 326 1.3E-25 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 Astex_2215 5c6fe9fe30bdd60e6cfca9a1afb120bf 350 Gene3D G3DSA:3.40.50.2000 159 330 6.2E-46 T 13-10-2018 Astex_2215 5c6fe9fe30bdd60e6cfca9a1afb120bf 350 Pfam PF13439 Glycosyltransferase Family 4 94 160 2.2E-7 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 Astex_2215 5c6fe9fe30bdd60e6cfca9a1afb120bf 350 SUPERFAMILY SSF53756 10 346 9.77E-59 T 13-10-2018 Astex_2215 5c6fe9fe30bdd60e6cfca9a1afb120bf 350 Gene3D G3DSA:3.40.50.2000 65 345 6.2E-46 T 13-10-2018 Astex_1338 1f66b8e883b5711e77225b633bebcbe3 797 Pfam PF07944 Beta-L-arabinofuranosidase, GH127 45 561 1.8E-151 T 13-10-2018 IPR012878 Beta-L-arabinofuranosidase, GH127 Astex_1338 1f66b8e883b5711e77225b633bebcbe3 797 SUPERFAMILY SSF48208 101 397 5.1E-16 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 Astex_1177 94087612ca8c2046265022301f14d3af 286 Gene3D G3DSA:3.30.2350.10 62 283 2.3E-56 T 13-10-2018 Astex_1177 94087612ca8c2046265022301f14d3af 286 Pfam PF00849 RNA pseudouridylate synthase 74 224 1.6E-26 T 13-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 Astex_1177 94087612ca8c2046265022301f14d3af 286 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 110 124 - T 13-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Astex_1177 94087612ca8c2046265022301f14d3af 286 SUPERFAMILY SSF55120 54 281 3.6E-53 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 Astex_1500 00097028157f6f9a315c4bf79eb06183 645 Gene3D G3DSA:3.40.1090.10 300 417 1.0E-18 T 13-10-2018 Astex_1500 00097028157f6f9a315c4bf79eb06183 645 SUPERFAMILY SSF51206 23 131 5.89E-24 T 13-10-2018 IPR018490 Cyclic nucleotide-binding-like Astex_1500 00097028157f6f9a315c4bf79eb06183 645 SMART SM00100 7 127 8.8E-11 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain Astex_1500 00097028157f6f9a315c4bf79eb06183 645 Gene3D G3DSA:2.60.120.10 19 136 6.9E-27 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Astex_1500 00097028157f6f9a315c4bf79eb06183 645 Pfam PF00027 Cyclic nucleotide-binding domain 29 113 8.2E-19 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain Astex_1500 00097028157f6f9a315c4bf79eb06183 645 Pfam PF01734 Patatin-like phospholipase 321 479 1.3E-18 T 13-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 Astex_1500 00097028157f6f9a315c4bf79eb06183 645 SUPERFAMILY SSF52151 315 551 4.71E-44 T 13-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase Astex_0990 673c2646af409238e7ad5dfa9464427a 307 SUPERFAMILY SSF56601 8 306 6.24E-102 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like Astex_0990 673c2646af409238e7ad5dfa9464427a 307 Hamap MF_00313 Glutaminase [glsA]. 7 307 43.198 T 13-10-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 Astex_0990 673c2646af409238e7ad5dfa9464427a 307 Gene3D G3DSA:3.40.710.10 3 307 1.3E-101 T 13-10-2018 Astex_0990 673c2646af409238e7ad5dfa9464427a 307 Pfam PF04960 Glutaminase 25 306 4.9E-103 T 13-10-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 Astex_0990 673c2646af409238e7ad5dfa9464427a 307 TIGRFAM TIGR03814 Gln_ase: glutaminase A 11 306 1.1E-113 T 13-10-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 Astex_2409 9e82b95b294cd12f9debb4d92425e2df 296 Gene3D G3DSA:1.10.1040.10 176 293 3.6E-36 T 13-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 Astex_2409 9e82b95b294cd12f9debb4d92425e2df 296 SUPERFAMILY SSF48179 168 267 2.27E-28 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Astex_2409 9e82b95b294cd12f9debb4d92425e2df 296 SUPERFAMILY SSF51735 5 157 1.58E-27 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_2409 9e82b95b294cd12f9debb4d92425e2df 296 Pfam PF09130 Domain of unknown function (DUF1932) 195 265 6.8E-18 T 13-10-2018 IPR015814 Phosphogluconate dehydrogenase, NAD-binding, putative, C-terminal Astex_2409 9e82b95b294cd12f9debb4d92425e2df 296 Gene3D G3DSA:3.40.50.720 6 174 1.3E-26 T 13-10-2018 Astex_2409 9e82b95b294cd12f9debb4d92425e2df 296 PIRSF PIRSF000103 238 296 34.0 T 13-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 Astex_2409 9e82b95b294cd12f9debb4d92425e2df 296 PIRSF PIRSF000103 1 217 3.7E-23 T 13-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 Astex_2409 9e82b95b294cd12f9debb4d92425e2df 296 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 6 125 3.6E-9 T 13-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 Astex_1650 6f32a93ed769fba9dfb751bc9ea4d309 511 SMART SM00387 399 511 5.5E-25 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_1650 6f32a93ed769fba9dfb751bc9ea4d309 511 PRINTS PR00344 Bacterial sensor protein C-terminal signature 451 461 3.4E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1650 6f32a93ed769fba9dfb751bc9ea4d309 511 PRINTS PR00344 Bacterial sensor protein C-terminal signature 433 447 3.4E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1650 6f32a93ed769fba9dfb751bc9ea4d309 511 PRINTS PR00344 Bacterial sensor protein C-terminal signature 468 486 3.4E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1650 6f32a93ed769fba9dfb751bc9ea4d309 511 Gene3D G3DSA:3.30.565.10 359 511 8.9E-28 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_1650 6f32a93ed769fba9dfb751bc9ea4d309 511 SMART SM00388 303 360 1.3E-4 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_1650 6f32a93ed769fba9dfb751bc9ea4d309 511 SUPERFAMILY SSF47384 287 357 8.83E-10 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Astex_1650 6f32a93ed769fba9dfb751bc9ea4d309 511 SMART SM00304 250 302 0.0018 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Astex_1650 6f32a93ed769fba9dfb751bc9ea4d309 511 SUPERFAMILY SSF55874 356 510 3.93E-30 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_1650 6f32a93ed769fba9dfb751bc9ea4d309 511 Gene3D G3DSA:1.10.287.130 248 354 5.4E-15 T 13-10-2018 Astex_1650 6f32a93ed769fba9dfb751bc9ea4d309 511 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 400 496 5.3E-18 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_1219 7020be325cc6daf2c2a3d4cd0fc2897a 758 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 406 640 1.3E-53 T 13-10-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 Astex_1219 7020be325cc6daf2c2a3d4cd0fc2897a 758 SUPERFAMILY SSF51445 35 405 2.21E-102 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_1219 7020be325cc6daf2c2a3d4cd0fc2897a 758 Pfam PF14310 Fibronectin type III-like domain 677 745 8.8E-19 T 13-10-2018 IPR026891 Fibronectin type III-like domain Astex_1219 7020be325cc6daf2c2a3d4cd0fc2897a 758 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 287 304 - T 13-10-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 Astex_1219 7020be325cc6daf2c2a3d4cd0fc2897a 758 SMART SM01217 677 746 4.5E-28 T 13-10-2018 IPR026891 Fibronectin type III-like domain Astex_1219 7020be325cc6daf2c2a3d4cd0fc2897a 758 SUPERFAMILY SSF52279 406 642 2.09E-50 T 13-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 Astex_1219 7020be325cc6daf2c2a3d4cd0fc2897a 758 Gene3D G3DSA:2.60.40.10 643 750 1.2E-29 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_1219 7020be325cc6daf2c2a3d4cd0fc2897a 758 Gene3D G3DSA:3.20.20.300 31 390 1.4E-116 T 13-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 Astex_1219 7020be325cc6daf2c2a3d4cd0fc2897a 758 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 49 366 1.7E-74 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_1219 7020be325cc6daf2c2a3d4cd0fc2897a 758 Gene3D G3DSA:3.40.50.1700 392 642 1.1E-74 T 13-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 Astex_1219 7020be325cc6daf2c2a3d4cd0fc2897a 758 PRINTS PR00133 Glycosyl hydrolase family 3 signature 134 153 2.8E-18 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_1219 7020be325cc6daf2c2a3d4cd0fc2897a 758 PRINTS PR00133 Glycosyl hydrolase family 3 signature 180 196 2.8E-18 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_1219 7020be325cc6daf2c2a3d4cd0fc2897a 758 PRINTS PR00133 Glycosyl hydrolase family 3 signature 115 131 2.8E-18 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_1219 7020be325cc6daf2c2a3d4cd0fc2897a 758 PRINTS PR00133 Glycosyl hydrolase family 3 signature 287 305 2.8E-18 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_1219 7020be325cc6daf2c2a3d4cd0fc2897a 758 PRINTS PR00133 Glycosyl hydrolase family 3 signature 217 233 2.8E-18 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_2613 fecdb4f448b4ef1ec8dba233eaedb015 658 Gene3D G3DSA:2.40.170.20 125 645 3.7E-14 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_2613 fecdb4f448b4ef1ec8dba233eaedb015 658 SUPERFAMILY SSF56935 25 627 2.2E-37 T 13-10-2018 Astex_0518 ae8d85a7ddc8706d777d8e4846a9356c 62 SMART SM00530 4 59 2.4E-16 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Astex_0518 ae8d85a7ddc8706d777d8e4846a9356c 62 SUPERFAMILY SSF47413 2 60 3.75E-18 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Astex_0518 ae8d85a7ddc8706d777d8e4846a9356c 62 Gene3D G3DSA:1.10.260.40 1 62 1.7E-27 T 13-10-2018 Astex_0518 ae8d85a7ddc8706d777d8e4846a9356c 62 Pfam PF01381 Helix-turn-helix 5 58 8.7E-15 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Astex_0186 9a0cf0c18b64fd050d5b1c238df958c1 89 Pfam PF00312 Ribosomal protein S15 8 88 4.9E-36 T 13-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_0186 9a0cf0c18b64fd050d5b1c238df958c1 89 SUPERFAMILY SSF47060 3 89 2.27E-34 T 13-10-2018 IPR009068 S15/NS1, RNA-binding Astex_0186 9a0cf0c18b64fd050d5b1c238df958c1 89 SMART SM01387 8 88 1.9E-50 T 13-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_0186 9a0cf0c18b64fd050d5b1c238df958c1 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 12 88 9.0E-30 T 13-10-2018 Astex_0186 9a0cf0c18b64fd050d5b1c238df958c1 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 21.914 T 13-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0186 9a0cf0c18b64fd050d5b1c238df958c1 89 Gene3D G3DSA:1.10.287.10 1 89 7.6E-34 T 13-10-2018 Astex_0186 9a0cf0c18b64fd050d5b1c238df958c1 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 89 7.1E-38 T 13-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0186 9a0cf0c18b64fd050d5b1c238df958c1 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 13-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_1561 7a3c954e2c1c3ee497156e1f7ed04dd5 948 SUPERFAMILY SSF53383 466 938 8.02E-99 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Astex_1561 7a3c954e2c1c3ee497156e1f7ed04dd5 948 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 16 936 0.0 T 13-10-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 Astex_1561 7a3c954e2c1c3ee497156e1f7ed04dd5 948 SUPERFAMILY SSF53383 16 439 1.79E-103 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Astex_1561 7a3c954e2c1c3ee497156e1f7ed04dd5 948 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 7 942 25.509 T 13-10-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 Astex_1561 7a3c954e2c1c3ee497156e1f7ed04dd5 948 Gene3D G3DSA:3.90.1150.10 751 886 1.1E-40 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Astex_1561 7a3c954e2c1c3ee497156e1f7ed04dd5 948 Gene3D G3DSA:3.40.640.10 94 352 2.0E-109 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Astex_1561 7a3c954e2c1c3ee497156e1f7ed04dd5 948 Gene3D G3DSA:3.40.640.10 514 738 2.1E-59 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Astex_1561 7a3c954e2c1c3ee497156e1f7ed04dd5 948 Pfam PF02347 Glycine cleavage system P-protein 15 438 3.0E-178 T 13-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 Astex_1561 7a3c954e2c1c3ee497156e1f7ed04dd5 948 Pfam PF02347 Glycine cleavage system P-protein 452 724 4.5E-7 T 13-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 Astex_0797 91bc145e42622b0bff9ba8f20060ed7a 153 Pfam PF10027 Predicted integral membrane protein (DUF2269) 5 153 2.3E-57 T 13-10-2018 IPR018729 Protein of unknown function DUF2269, transmembrane Astex_3072 d3e200e7c622cf434e5ac9911222de6e 255 SUPERFAMILY SSF81901 47 237 3.4E-35 T 13-10-2018 Astex_3072 d3e200e7c622cf434e5ac9911222de6e 255 Gene3D G3DSA:1.25.40.10 34 135 1.1E-22 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_3072 d3e200e7c622cf434e5ac9911222de6e 255 SMART SM00671 136 171 0.052 T 13-10-2018 IPR006597 Sel1-like repeat Astex_3072 d3e200e7c622cf434e5ac9911222de6e 255 SMART SM00671 172 207 7.7 T 13-10-2018 IPR006597 Sel1-like repeat Astex_3072 d3e200e7c622cf434e5ac9911222de6e 255 SMART SM00671 100 135 3.5E-7 T 13-10-2018 IPR006597 Sel1-like repeat Astex_3072 d3e200e7c622cf434e5ac9911222de6e 255 SMART SM00671 64 99 2.0E-8 T 13-10-2018 IPR006597 Sel1-like repeat Astex_3072 d3e200e7c622cf434e5ac9911222de6e 255 Pfam PF08238 Sel1 repeat 172 199 10.0 T 13-10-2018 IPR006597 Sel1-like repeat Astex_3072 d3e200e7c622cf434e5ac9911222de6e 255 Pfam PF08238 Sel1 repeat 142 170 0.011 T 13-10-2018 IPR006597 Sel1-like repeat Astex_3072 d3e200e7c622cf434e5ac9911222de6e 255 Pfam PF08238 Sel1 repeat 66 99 1.6E-8 T 13-10-2018 IPR006597 Sel1-like repeat Astex_3072 d3e200e7c622cf434e5ac9911222de6e 255 Pfam PF08238 Sel1 repeat 100 131 1.8E-5 T 13-10-2018 IPR006597 Sel1-like repeat Astex_3072 d3e200e7c622cf434e5ac9911222de6e 255 Gene3D G3DSA:1.25.40.10 136 254 1.9E-18 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_1492 281ea84b1f592d696fe3b31750dc2484 484 SUPERFAMILY SSF53187 49 474 2.45E-53 T 13-10-2018 Astex_1492 281ea84b1f592d696fe3b31750dc2484 484 Pfam PF04389 Peptidase family M28 274 464 4.4E-26 T 13-10-2018 IPR007484 Peptidase M28 Astex_1492 281ea84b1f592d696fe3b31750dc2484 484 Gene3D G3DSA:3.40.630.10 57 466 1.1E-130 T 13-10-2018 Astex_1492 281ea84b1f592d696fe3b31750dc2484 484 Gene3D G3DSA:3.50.30.30 110 263 1.1E-130 T 13-10-2018 Astex_2351 2f6df2d093269264848e2228aa4389a5 304 Gene3D G3DSA:2.40.70.10 19 149 9.5E-13 T 13-10-2018 IPR021109 Aspartic peptidase domain superfamily Astex_2351 2f6df2d093269264848e2228aa4389a5 304 Gene3D G3DSA:2.40.70.10 164 290 1.0E-12 T 13-10-2018 IPR021109 Aspartic peptidase domain superfamily Astex_2351 2f6df2d093269264848e2228aa4389a5 304 SUPERFAMILY SSF50630 169 281 1.8E-7 T 13-10-2018 IPR021109 Aspartic peptidase domain superfamily Astex_2351 2f6df2d093269264848e2228aa4389a5 304 SUPERFAMILY SSF50630 30 105 1.6E-7 T 13-10-2018 IPR021109 Aspartic peptidase domain superfamily Astex_2351 2f6df2d093269264848e2228aa4389a5 304 Pfam PF13650 Aspartyl protease 41 110 9.8E-9 T 13-10-2018 Astex_2351 2f6df2d093269264848e2228aa4389a5 304 Pfam PF13650 Aspartyl protease 177 272 4.0E-15 T 13-10-2018 Astex_2633 a2089148ae64332aa061050ab9d734ef 150 Pfam PF03061 Thioesterase superfamily 52 123 2.8E-10 T 13-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 Astex_2633 a2089148ae64332aa061050ab9d734ef 150 Gene3D G3DSA:3.10.129.10 4 145 1.1E-48 T 13-10-2018 Astex_2633 a2089148ae64332aa061050ab9d734ef 150 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 20 114 3.4E-10 T 13-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 Astex_2633 a2089148ae64332aa061050ab9d734ef 150 SUPERFAMILY SSF54637 8 138 3.28E-25 T 13-10-2018 IPR029069 HotDog domain superfamily Astex_2206 a6e8f0e127f42220e04e68a90fdaaab0 449 SUPERFAMILY SSF82171 271 447 7.85E-8 T 13-10-2018 Astex_2206 a6e8f0e127f42220e04e68a90fdaaab0 449 Gene3D G3DSA:2.120.10.30 268 431 1.4E-9 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like Astex_2206 a6e8f0e127f42220e04e68a90fdaaab0 449 SUPERFAMILY SSF69304 47 193 4.05E-6 T 13-10-2018 Astex_2408 5a9155db9ae89166520a9fa73f1ad7fc 362 SUPERFAMILY SSF54506 2 169 1.49E-64 T 13-10-2018 Astex_2408 5a9155db9ae89166520a9fa73f1ad7fc 362 Gene3D G3DSA:3.10.310.10 168 337 2.2E-116 T 13-10-2018 Astex_2408 5a9155db9ae89166520a9fa73f1ad7fc 362 SUPERFAMILY SSF54506 173 357 1.07E-54 T 13-10-2018 Astex_2408 5a9155db9ae89166520a9fa73f1ad7fc 362 Gene3D G3DSA:3.10.310.10 6 350 2.2E-116 T 13-10-2018 Astex_2408 5a9155db9ae89166520a9fa73f1ad7fc 362 Pfam PF04303 PrpF protein 5 353 1.1E-107 T 13-10-2018 IPR007400 PrpF protein Astex_1864 161de25f88743cb0cb42b123d0f3b251 241 SUPERFAMILY SSF53335 20 208 6.21E-26 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Astex_1864 161de25f88743cb0cb42b123d0f3b251 241 Pfam PF08241 Methyltransferase domain 44 138 3.2E-13 T 13-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 Astex_1864 161de25f88743cb0cb42b123d0f3b251 241 Gene3D G3DSA:3.40.50.150 11 187 1.8E-23 T 13-10-2018 Astex_1453 512a73140ae899b0a9c59132d4e84b14 297 SUPERFAMILY SSF103481 38 137 2.09E-10 T 13-10-2018 Astex_1453 512a73140ae899b0a9c59132d4e84b14 297 SUPERFAMILY SSF103481 197 289 4.05E-13 T 13-10-2018 Astex_1453 512a73140ae899b0a9c59132d4e84b14 297 Pfam PF00892 EamA-like transporter family 9 136 1.9E-17 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Astex_1453 512a73140ae899b0a9c59132d4e84b14 297 Pfam PF00892 EamA-like transporter family 151 286 2.0E-18 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Astex_1746 60db3d4dfc29405399a133007acd1a3b 344 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 32 134 2.2E-31 T 13-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Astex_1746 60db3d4dfc29405399a133007acd1a3b 344 Pfam PF00107 Zinc-binding dehydrogenase 179 305 1.8E-26 T 13-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Astex_1746 60db3d4dfc29405399a133007acd1a3b 344 Gene3D G3DSA:3.90.180.10 14 337 6.5E-138 T 13-10-2018 Astex_1746 60db3d4dfc29405399a133007acd1a3b 344 SUPERFAMILY SSF50129 2 184 1.08E-53 T 13-10-2018 IPR011032 GroES-like superfamily Astex_1746 60db3d4dfc29405399a133007acd1a3b 344 Gene3D G3DSA:3.40.50.720 152 291 6.5E-138 T 13-10-2018 Astex_1746 60db3d4dfc29405399a133007acd1a3b 344 SMART SM00829 14 340 1.7E-6 T 13-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Astex_1746 60db3d4dfc29405399a133007acd1a3b 344 SUPERFAMILY SSF51735 141 311 1.58E-44 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_1746 60db3d4dfc29405399a133007acd1a3b 344 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 64 78 - T 13-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 Astex_1231 47de6c329d72710282446a292a875205 1004 Gene3D G3DSA:2.170.130.10 57 187 2.3E-31 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_1231 47de6c329d72710282446a292a875205 1004 Pfam PF00593 TonB dependent receptor 426 1002 1.5E-39 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_1231 47de6c329d72710282446a292a875205 1004 Pfam PF07715 TonB-dependent Receptor Plug Domain 77 183 4.6E-18 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_1231 47de6c329d72710282446a292a875205 1004 SUPERFAMILY SSF56935 49 1004 3.92E-84 T 13-10-2018 Astex_2897 267694c93af8efbd85c34ebccb16430f 250 Pfam PF00121 Triosephosphate isomerase 6 246 1.3E-70 T 13-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_2897 267694c93af8efbd85c34ebccb16430f 250 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 3 248 45.563 T 13-10-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_2897 267694c93af8efbd85c34ebccb16430f 250 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 6 240 1.6E-42 T 13-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_2897 267694c93af8efbd85c34ebccb16430f 250 ProSitePatterns PS00171 Triosephosphate isomerase active site. 166 176 - T 13-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_2897 267694c93af8efbd85c34ebccb16430f 250 Gene3D G3DSA:3.20.20.70 1 250 5.3E-81 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_2897 267694c93af8efbd85c34ebccb16430f 250 SUPERFAMILY SSF51351 2 248 1.96E-74 T 13-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_0960 d16c215fc0c566276f9ae7c81b82ed67 177 Gene3D G3DSA:3.90.930.12 1 82 1.0E-30 T 13-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0960 d16c215fc0c566276f9ae7c81b82ed67 177 PRINTS PR00059 Ribosomal protein L6 signature 141 162 5.1E-34 T 13-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 Astex_0960 d16c215fc0c566276f9ae7c81b82ed67 177 PRINTS PR00059 Ribosomal protein L6 signature 71 96 5.1E-34 T 13-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 Astex_0960 d16c215fc0c566276f9ae7c81b82ed67 177 PRINTS PR00059 Ribosomal protein L6 signature 99 115 5.1E-34 T 13-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 Astex_0960 d16c215fc0c566276f9ae7c81b82ed67 177 SUPERFAMILY SSF56053 83 177 6.68E-36 T 13-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0960 d16c215fc0c566276f9ae7c81b82ed67 177 Gene3D G3DSA:3.90.930.12 83 177 3.6E-40 T 13-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0960 d16c215fc0c566276f9ae7c81b82ed67 177 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 2.9E-75 T 13-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 Astex_0960 d16c215fc0c566276f9ae7c81b82ed67 177 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 38.216 T 13-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 Astex_0960 d16c215fc0c566276f9ae7c81b82ed67 177 PIRSF PIRSF002162 1 177 1.5E-49 T 13-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0960 d16c215fc0c566276f9ae7c81b82ed67 177 Pfam PF00347 Ribosomal protein L6 11 82 1.1E-19 T 13-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0960 d16c215fc0c566276f9ae7c81b82ed67 177 Pfam PF00347 Ribosomal protein L6 90 164 4.0E-21 T 13-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0960 d16c215fc0c566276f9ae7c81b82ed67 177 SUPERFAMILY SSF56053 1 82 2.16E-25 T 13-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0960 d16c215fc0c566276f9ae7c81b82ed67 177 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 13-10-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_0874 2beadfd3cc7a3cb2d57e23a2215cf3c7 541 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 59 222 3.4E-25 T 13-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like Astex_1663 02c833da8f14a6c4f78ef1ec09b23d7a 188 SUPERFAMILY SSF48498 77 182 2.09E-15 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily Astex_1663 02c833da8f14a6c4f78ef1ec09b23d7a 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 2.0E-8 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Astex_1663 02c833da8f14a6c4f78ef1ec09b23d7a 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 2.0E-8 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Astex_1663 02c833da8f14a6c4f78ef1ec09b23d7a 188 SUPERFAMILY SSF46689 3 74 9.98E-17 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Astex_1663 02c833da8f14a6c4f78ef1ec09b23d7a 188 Gene3D G3DSA:1.10.357.10 1 187 9.1E-45 T 13-10-2018 Astex_1663 02c833da8f14a6c4f78ef1ec09b23d7a 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 55 1.0E-11 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Astex_0172 15b6c9d58f427be2f27e2c50294957ed 390 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 236 379 3.0E-59 T 13-10-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Astex_0172 15b6c9d58f427be2f27e2c50294957ed 390 SUPERFAMILY SSF55973 236 388 6.67E-60 T 13-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Astex_0172 15b6c9d58f427be2f27e2c50294957ed 390 Gene3D G3DSA:3.30.300.10 107 381 8.9E-148 T 13-10-2018 Astex_0172 15b6c9d58f427be2f27e2c50294957ed 390 Gene3D G3DSA:3.30.300.10 6 236 8.9E-148 T 13-10-2018 Astex_0172 15b6c9d58f427be2f27e2c50294957ed 390 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 262 270 - T 13-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Astex_0172 15b6c9d58f427be2f27e2c50294957ed 390 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 6 388 1.7E-134 T 13-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Astex_0172 15b6c9d58f427be2f27e2c50294957ed 390 Pfam PF02772 S-adenosylmethionine synthetase, central domain 120 234 2.8E-31 T 13-10-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Astex_0172 15b6c9d58f427be2f27e2c50294957ed 390 SUPERFAMILY SSF55973 116 235 2.47E-35 T 13-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Astex_0172 15b6c9d58f427be2f27e2c50294957ed 390 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 4 106 3.1E-35 T 13-10-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Astex_0172 15b6c9d58f427be2f27e2c50294957ed 390 PIRSF PIRSF000497 1 390 6.2E-143 T 13-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Astex_0172 15b6c9d58f427be2f27e2c50294957ed 390 SUPERFAMILY SSF55973 4 114 2.28E-35 T 13-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Astex_0172 15b6c9d58f427be2f27e2c50294957ed 390 Gene3D G3DSA:3.30.300.10 12 273 8.9E-148 T 13-10-2018 Astex_0172 15b6c9d58f427be2f27e2c50294957ed 390 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 121 131 - T 13-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 Astex_2892 3f533746c2af81a18e92e418a4e5cdb0 370 Gene3D G3DSA:3.40.190.10 155 250 7.6E-54 T 13-10-2018 Astex_2892 3f533746c2af81a18e92e418a4e5cdb0 370 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 86 99 - T 13-10-2018 IPR018313 Solute-binding protein family 3, conserved site Astex_2892 3f533746c2af81a18e92e418a4e5cdb0 370 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 65 274 1.3E-31 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF Astex_2892 3f533746c2af81a18e92e418a4e5cdb0 370 SUPERFAMILY SSF53850 54 279 3.03E-47 T 13-10-2018 Astex_2892 3f533746c2af81a18e92e418a4e5cdb0 370 Gene3D G3DSA:3.40.190.10 53 275 7.6E-54 T 13-10-2018 Astex_2892 3f533746c2af81a18e92e418a4e5cdb0 370 SMART SM00062 63 292 4.1E-44 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF Astex_3106 6a2adeab42d9232b2cc4eb5a1e52306e 277 Pfam PF00700 Bacterial flagellin C-terminal helical region 193 276 1.1E-14 T 13-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 Astex_3106 6a2adeab42d9232b2cc4eb5a1e52306e 277 Gene3D G3DSA:1.10.8.410 234 277 1.4E-7 T 13-10-2018 Astex_3106 6a2adeab42d9232b2cc4eb5a1e52306e 277 SUPERFAMILY SSF64518 4 277 3.4E-59 T 13-10-2018 Astex_3106 6a2adeab42d9232b2cc4eb5a1e52306e 277 Pfam PF00669 Bacterial flagellin N-terminal helical region 6 142 2.3E-22 T 13-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 Astex_3106 6a2adeab42d9232b2cc4eb5a1e52306e 277 Gene3D G3DSA:1.20.1330.10 44 231 1.3E-19 T 13-10-2018 Astex_0623 5cc08dd4d4120937f9ddfaaae83fa3ae 149 SUPERFAMILY SSF82649 17 148 6.8E-44 T 13-10-2018 Astex_0623 5cc08dd4d4120937f9ddfaaae83fa3ae 149 Pfam PF02657 Fe-S metabolism associated domain 26 146 5.1E-43 T 13-10-2018 IPR003808 Fe-S metabolism associated domain, SufE-like Astex_0623 5cc08dd4d4120937f9ddfaaae83fa3ae 149 Gene3D G3DSA:3.90.1010.10 17 149 3.2E-47 T 13-10-2018 Astex_1130 be7a95e7f1db4473ddec2d23df599345 269 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 178 239 4.5E-5 T 13-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 Astex_1130 be7a95e7f1db4473ddec2d23df599345 269 Gene3D G3DSA:3.30.70.1400 10 103 1.3E-22 T 13-10-2018 Astex_1130 be7a95e7f1db4473ddec2d23df599345 269 SUPERFAMILY SSF103025 4 193 1.26E-38 T 13-10-2018 Astex_1130 be7a95e7f1db4473ddec2d23df599345 269 Gene3D G3DSA:3.30.1360.120 116 246 4.3E-18 T 13-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 Astex_1130 be7a95e7f1db4473ddec2d23df599345 269 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 138 203 2.3E-19 T 13-10-2018 IPR017703 YgfZ/GcvT conserved site Astex_2778 982fbb96d4bb64aab9a773e5c59185d8 112 PRINTS PR00340 P-II protein signature 83 103 3.2E-41 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Astex_2778 982fbb96d4bb64aab9a773e5c59185d8 112 PRINTS PR00340 P-II protein signature 52 75 3.2E-41 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Astex_2778 982fbb96d4bb64aab9a773e5c59185d8 112 PRINTS PR00340 P-II protein signature 2 17 3.2E-41 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Astex_2778 982fbb96d4bb64aab9a773e5c59185d8 112 PRINTS PR00340 P-II protein signature 23 41 3.2E-41 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Astex_2778 982fbb96d4bb64aab9a773e5c59185d8 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 13-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 Astex_2778 982fbb96d4bb64aab9a773e5c59185d8 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 13-10-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 Astex_2778 982fbb96d4bb64aab9a773e5c59185d8 112 SUPERFAMILY SSF54913 1 112 5.4E-44 T 13-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta Astex_2778 982fbb96d4bb64aab9a773e5c59185d8 112 PIRSF PIRSF039144 1 112 1.6E-52 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Astex_2778 982fbb96d4bb64aab9a773e5c59185d8 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 3.6E-41 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Astex_2778 982fbb96d4bb64aab9a773e5c59185d8 112 SMART SM00938 4 105 2.1E-65 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 Astex_2778 982fbb96d4bb64aab9a773e5c59185d8 112 Gene3D G3DSA:3.30.70.120 1 112 8.2E-46 T 13-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal Astex_0011 8a51a88a972de2dee6b0f79fb4917af2 264 PIRSF PIRSF000126 1 264 2.3E-54 T 13-10-2018 Astex_0011 8a51a88a972de2dee6b0f79fb4917af2 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.6E-6 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0011 8a51a88a972de2dee6b0f79fb4917af2 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 1.6E-6 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0011 8a51a88a972de2dee6b0f79fb4917af2 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 1.6E-6 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0011 8a51a88a972de2dee6b0f79fb4917af2 264 Pfam PF00106 short chain dehydrogenase 4 191 3.7E-38 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0011 8a51a88a972de2dee6b0f79fb4917af2 264 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 184 0.0018 T 13-10-2018 Astex_0011 8a51a88a972de2dee6b0f79fb4917af2 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 2.2E-21 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0011 8a51a88a972de2dee6b0f79fb4917af2 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 2.2E-21 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0011 8a51a88a972de2dee6b0f79fb4917af2 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 2.2E-21 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0011 8a51a88a972de2dee6b0f79fb4917af2 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 2.2E-21 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0011 8a51a88a972de2dee6b0f79fb4917af2 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 2.2E-21 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0011 8a51a88a972de2dee6b0f79fb4917af2 264 SUPERFAMILY SSF51735 3 253 1.06E-55 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_0011 8a51a88a972de2dee6b0f79fb4917af2 264 Gene3D G3DSA:3.40.50.720 2 252 7.2E-53 T 13-10-2018 Astex_3403 c65277058f319768363d5f7e3e388b8d 621 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 212 227 - T 13-10-2018 IPR019826 Carboxylesterase type B, active site Astex_3403 c65277058f319768363d5f7e3e388b8d 621 Gene3D G3DSA:3.40.50.1820 4 534 4.5E-132 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_3403 c65277058f319768363d5f7e3e388b8d 621 SUPERFAMILY SSF53474 36 511 1.14E-111 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_3403 c65277058f319768363d5f7e3e388b8d 621 ProSitePatterns PS00941 Carboxylesterases type-B signature 2. 110 120 - T 13-10-2018 IPR019819 Carboxylesterase type B, conserved site Astex_3403 c65277058f319768363d5f7e3e388b8d 621 Pfam PF00135 Carboxylesterase family 37 513 8.1E-104 T 13-10-2018 IPR002018 Carboxylesterase, type B Astex_2994 9477f526293e606bf77e343a767b9c9d 808 Gene3D G3DSA:3.40.710.10 408 761 2.7E-110 T 13-10-2018 Astex_2994 9477f526293e606bf77e343a767b9c9d 808 Pfam PF00912 Transglycosylase 59 236 4.6E-60 T 13-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Astex_2994 9477f526293e606bf77e343a767b9c9d 808 SUPERFAMILY SSF53955 46 261 7.59E-71 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily Astex_2994 9477f526293e606bf77e343a767b9c9d 808 SUPERFAMILY SSF56601 218 758 3.91E-120 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like Astex_2994 9477f526293e606bf77e343a767b9c9d 808 Gene3D G3DSA:3.40.710.10 300 314 3.4E-81 T 13-10-2018 Astex_2994 9477f526293e606bf77e343a767b9c9d 808 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 69 725 8.3E-178 T 13-10-2018 Astex_2994 9477f526293e606bf77e343a767b9c9d 808 Gene3D G3DSA:3.90.1310.20 58 299 3.4E-81 T 13-10-2018 Astex_2994 9477f526293e606bf77e343a767b9c9d 808 Gene3D G3DSA:1.10.3810.10 69 263 3.4E-81 T 13-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Astex_2994 9477f526293e606bf77e343a767b9c9d 808 Pfam PF00905 Penicillin binding protein transpeptidase domain 428 719 6.0E-33 T 13-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 Astex_2994 9477f526293e606bf77e343a767b9c9d 808 Pfam PF17092 Penicillin-binding protein OB-like domain 324 426 1.7E-7 T 13-10-2018 IPR031376 Penicillin-binding protein, OB-like domain KEGG: 00550+2.4.1.129+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Astex_0392 da3c72a1dd2edc994f3311174ecbd7e2 277 Gene3D G3DSA:3.40.50.1820 36 277 3.2E-24 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_0392 da3c72a1dd2edc994f3311174ecbd7e2 277 Pfam PF00326 Prolyl oligopeptidase family 132 256 1.8E-8 T 13-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 Astex_0392 da3c72a1dd2edc994f3311174ecbd7e2 277 SUPERFAMILY SSF53474 53 276 2.78E-21 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_0692 dbdf414e560fa25200519137528b35d7 519 Gene3D G3DSA:1.10.287.130 130 222 8.3E-19 T 13-10-2018 Astex_0692 dbdf414e560fa25200519137528b35d7 519 SMART SM00387 270 383 2.2E-36 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_0692 dbdf414e560fa25200519137528b35d7 519 Gene3D G3DSA:3.30.565.10 232 390 5.0E-41 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_0692 dbdf414e560fa25200519137528b35d7 519 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 270 382 1.6E-24 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_0692 dbdf414e560fa25200519137528b35d7 519 SMART SM00388 159 224 2.2E-15 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_0692 dbdf414e560fa25200519137528b35d7 519 Pfam PF00512 His Kinase A (phospho-acceptor) domain 161 223 9.9E-12 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_0692 dbdf414e560fa25200519137528b35d7 519 Pfam PF00072 Response regulator receiver domain 7 119 1.2E-22 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_0692 dbdf414e560fa25200519137528b35d7 519 Pfam PF00072 Response regulator receiver domain 403 511 1.5E-23 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_0692 dbdf414e560fa25200519137528b35d7 519 Gene3D G3DSA:3.40.50.12740 400 519 8.6E-37 T 13-10-2018 Astex_0692 dbdf414e560fa25200519137528b35d7 519 SUPERFAMILY SSF55874 213 383 1.11E-44 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_0692 dbdf414e560fa25200519137528b35d7 519 SUPERFAMILY SSF52172 401 517 3.27E-35 T 13-10-2018 IPR011006 CheY-like superfamily Astex_0692 dbdf414e560fa25200519137528b35d7 519 SUPERFAMILY SSF47384 145 225 6.28E-17 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Astex_0692 dbdf414e560fa25200519137528b35d7 519 Gene3D G3DSA:3.40.50.2300 2 129 5.8E-32 T 13-10-2018 Astex_0692 dbdf414e560fa25200519137528b35d7 519 PRINTS PR00344 Bacterial sensor protein C-terminal signature 307 321 3.1E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_0692 dbdf414e560fa25200519137528b35d7 519 PRINTS PR00344 Bacterial sensor protein C-terminal signature 342 360 3.1E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_0692 dbdf414e560fa25200519137528b35d7 519 PRINTS PR00344 Bacterial sensor protein C-terminal signature 325 335 3.1E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_0692 dbdf414e560fa25200519137528b35d7 519 PRINTS PR00344 Bacterial sensor protein C-terminal signature 367 380 3.1E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_0692 dbdf414e560fa25200519137528b35d7 519 SMART SM00448 401 517 2.9E-31 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_0692 dbdf414e560fa25200519137528b35d7 519 SMART SM00448 5 119 4.3E-30 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_0692 dbdf414e560fa25200519137528b35d7 519 SUPERFAMILY SSF52172 4 156 2.7E-35 T 13-10-2018 IPR011006 CheY-like superfamily Astex_1247 f8fd60ee318a55a3c48e9b56db2d7166 976 Gene3D G3DSA:1.10.8.280 309 425 1.3E-242 T 13-10-2018 Astex_1247 f8fd60ee318a55a3c48e9b56db2d7166 976 Gene3D G3DSA:1.20.1580.10 108 516 1.3E-242 T 13-10-2018 Astex_1247 f8fd60ee318a55a3c48e9b56db2d7166 976 Gene3D G3DSA:1.20.1580.10 721 859 3.2E-134 T 13-10-2018 Astex_1247 f8fd60ee318a55a3c48e9b56db2d7166 976 Hamap MF_00205 UvrABC system protein A [uvrA]. 19 969 22.337 T 13-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 Astex_1247 f8fd60ee318a55a3c48e9b56db2d7166 976 SUPERFAMILY SSF52540 23 593 3.32E-46 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1247 f8fd60ee318a55a3c48e9b56db2d7166 976 SUPERFAMILY SSF52540 648 939 6.01E-44 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1247 f8fd60ee318a55a3c48e9b56db2d7166 976 Gene3D G3DSA:3.30.190.20 148 262 1.3E-242 T 13-10-2018 Astex_1247 f8fd60ee318a55a3c48e9b56db2d7166 976 ProSitePatterns PS00211 ABC transporters family signature. 511 525 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Astex_1247 f8fd60ee318a55a3c48e9b56db2d7166 976 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 22 954 0.0 T 13-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 Astex_1247 f8fd60ee318a55a3c48e9b56db2d7166 976 Gene3D G3DSA:3.40.50.300 646 965 3.2E-134 T 13-10-2018 Astex_1247 f8fd60ee318a55a3c48e9b56db2d7166 976 ProSitePatterns PS00211 ABC transporters family signature. 859 873 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Astex_1247 f8fd60ee318a55a3c48e9b56db2d7166 976 Gene3D G3DSA:3.40.50.300 24 619 1.3E-242 T 13-10-2018 Astex_3180 e74db6abb36e3e1a94a9ec837c193bd4 494 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 12 485 88.47 T 13-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Astex_3180 e74db6abb36e3e1a94a9ec837c193bd4 494 Pfam PF01425 Amidase 25 474 2.3E-146 T 13-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Astex_3180 e74db6abb36e3e1a94a9ec837c193bd4 494 SUPERFAMILY SSF75304 3 491 1.7E-151 T 13-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Astex_3180 e74db6abb36e3e1a94a9ec837c193bd4 494 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 16 483 1.5E-165 T 13-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Astex_3180 e74db6abb36e3e1a94a9ec837c193bd4 494 Gene3D G3DSA:3.90.1300.10 4 493 2.7E-178 T 13-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Astex_3180 e74db6abb36e3e1a94a9ec837c193bd4 494 ProSitePatterns PS00571 Amidases signature. 157 188 - T 13-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 Astex_3424 3fe7254318f32c8794f36d81023c08e1 191 Pfam PF04542 Sigma-70 region 2 19 80 1.5E-6 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 Astex_3424 3fe7254318f32c8794f36d81023c08e1 191 Gene3D G3DSA:1.10.10.10 95 173 1.1E-15 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_3424 3fe7254318f32c8794f36d81023c08e1 191 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 167 3.7E-24 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 Astex_3424 3fe7254318f32c8794f36d81023c08e1 191 Pfam PF08281 Sigma-70, region 4 114 163 2.9E-14 T 13-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Astex_3424 3fe7254318f32c8794f36d81023c08e1 191 Gene3D G3DSA:1.10.1740.10 10 81 5.3E-7 T 13-10-2018 Astex_3424 3fe7254318f32c8794f36d81023c08e1 191 SUPERFAMILY SSF88659 95 171 3.92E-15 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Astex_3424 3fe7254318f32c8794f36d81023c08e1 191 SUPERFAMILY SSF88946 17 95 2.83E-10 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 Astex_0410 74a18f5f7876b616457ae8f58a34bcad 333 SUPERFAMILY SSF51197 19 329 3.71E-76 T 13-10-2018 Astex_0410 74a18f5f7876b616457ae8f58a34bcad 333 Pfam PF14226 non-haem dioxygenase in morphine synthesis N-terminal 26 141 7.9E-21 T 13-10-2018 IPR026992 Non-haem dioxygenase N-terminal domain Astex_0410 74a18f5f7876b616457ae8f58a34bcad 333 Pfam PF03171 2OG-Fe(II) oxygenase superfamily 189 290 3.8E-16 T 13-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 Astex_0410 74a18f5f7876b616457ae8f58a34bcad 333 Gene3D G3DSA:2.60.120.330 15 333 7.4E-103 T 13-10-2018 IPR027443 Isopenicillin N synthase-like Astex_3489 649acd70da35b1e18e09cc651c7702d9 55 Gene3D G3DSA:2.20.28.120 1 55 4.7E-26 T 13-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_3489 649acd70da35b1e18e09cc651c7702d9 55 SUPERFAMILY SSF57829 2 53 1.22E-16 T 13-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 Astex_3489 649acd70da35b1e18e09cc651c7702d9 55 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 55 1.4E-22 T 13-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_3489 649acd70da35b1e18e09cc651c7702d9 55 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 2 53 13.089 T 13-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_3489 649acd70da35b1e18e09cc651c7702d9 55 Pfam PF00471 Ribosomal protein L33 7 53 6.9E-16 T 13-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_3489 649acd70da35b1e18e09cc651c7702d9 55 ProSitePatterns PS00582 Ribosomal protein L33 signature. 21 40 - T 13-10-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_3604 dacf69ab843d4822dca2710d532be409 1043 PRINTS PR00132 Glycosyl hydrolase family 2 signature 551 566 3.4E-33 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_3604 dacf69ab843d4822dca2710d532be409 1043 PRINTS PR00132 Glycosyl hydrolase family 2 signature 392 410 3.4E-33 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_3604 dacf69ab843d4822dca2710d532be409 1043 PRINTS PR00132 Glycosyl hydrolase family 2 signature 173 188 3.4E-33 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_3604 dacf69ab843d4822dca2710d532be409 1043 PRINTS PR00132 Glycosyl hydrolase family 2 signature 472 487 3.4E-33 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_3604 dacf69ab843d4822dca2710d532be409 1043 PRINTS PR00132 Glycosyl hydrolase family 2 signature 361 375 3.4E-33 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_3604 dacf69ab843d4822dca2710d532be409 1043 SUPERFAMILY SSF51445 352 643 7.18E-82 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_3604 dacf69ab843d4822dca2710d532be409 1043 SMART SM01038 768 1037 1.1E-68 T 13-10-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_3604 dacf69ab843d4822dca2710d532be409 1043 SUPERFAMILY SSF49785 35 246 1.42E-55 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_3604 dacf69ab843d4822dca2710d532be409 1043 Pfam PF02929 Beta galactosidase small chain 775 1036 7.6E-54 T 13-10-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_3604 dacf69ab843d4822dca2710d532be409 1043 ProSitePatterns PS00719 Glycosyl hydrolases family 2 signature 1. 402 427 - T 13-10-2018 IPR023230 Glycoside hydrolase, family 2, conserved site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_3604 dacf69ab843d4822dca2710d532be409 1043 SUPERFAMILY SSF49303 641 748 3.24E-19 T 13-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily Astex_3604 dacf69ab843d4822dca2710d532be409 1043 Gene3D G3DSA:2.60.40.10 644 749 4.7E-19 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_3604 dacf69ab843d4822dca2710d532be409 1043 Gene3D G3DSA:2.60.40.10 248 350 8.6E-22 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_3604 dacf69ab843d4822dca2710d532be409 1043 Gene3D G3DSA:2.70.98.10 773 1040 2.1E-63 T 13-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 Astex_3604 dacf69ab843d4822dca2710d532be409 1043 Gene3D G3DSA:3.20.20.80 351 643 7.9E-103 T 13-10-2018 Astex_3604 dacf69ab843d4822dca2710d532be409 1043 Pfam PF00703 Glycosyl hydrolases family 2 247 350 3.4E-11 T 13-10-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_3604 dacf69ab843d4822dca2710d532be409 1043 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 352 648 1.3E-95 T 13-10-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 Astex_3604 dacf69ab843d4822dca2710d532be409 1043 SUPERFAMILY SSF74650 757 1037 1.73E-62 T 13-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 Astex_3604 dacf69ab843d4822dca2710d532be409 1043 ProSitePatterns PS00608 Glycosyl hydrolases family 2 acid/base catalyst. 472 486 - T 13-10-2018 IPR023232 Glycoside hydrolase, family 2, active site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_3604 dacf69ab843d4822dca2710d532be409 1043 SUPERFAMILY SSF49303 247 350 8.63E-20 T 13-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily Astex_3604 dacf69ab843d4822dca2710d532be409 1043 Pfam PF16353 Domain of unknown function(DUF4981) 657 744 3.9E-14 T 13-10-2018 IPR032312 Beta-galactosidase, domain 4 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_3604 dacf69ab843d4822dca2710d532be409 1043 Gene3D G3DSA:2.60.120.260 29 246 8.6E-77 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_3604 dacf69ab843d4822dca2710d532be409 1043 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 75 245 5.0E-31 T 13-10-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_1225 fe81f11cc3160584997fa0bc625c7ca8 1040 Gene3D G3DSA:2.70.98.10 772 1039 1.9E-65 T 13-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 Astex_1225 fe81f11cc3160584997fa0bc625c7ca8 1040 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 65 235 2.3E-31 T 13-10-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_1225 fe81f11cc3160584997fa0bc625c7ca8 1040 Pfam PF16353 Domain of unknown function(DUF4981) 656 744 3.1E-13 T 13-10-2018 IPR032312 Beta-galactosidase, domain 4 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_1225 fe81f11cc3160584997fa0bc625c7ca8 1040 Gene3D G3DSA:2.60.120.260 18 236 1.8E-76 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_1225 fe81f11cc3160584997fa0bc625c7ca8 1040 PRINTS PR00132 Glycosyl hydrolase family 2 signature 351 365 8.9E-35 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_1225 fe81f11cc3160584997fa0bc625c7ca8 1040 PRINTS PR00132 Glycosyl hydrolase family 2 signature 549 564 8.9E-35 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_1225 fe81f11cc3160584997fa0bc625c7ca8 1040 PRINTS PR00132 Glycosyl hydrolase family 2 signature 382 400 8.9E-35 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_1225 fe81f11cc3160584997fa0bc625c7ca8 1040 PRINTS PR00132 Glycosyl hydrolase family 2 signature 163 178 8.9E-35 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_1225 fe81f11cc3160584997fa0bc625c7ca8 1040 PRINTS PR00132 Glycosyl hydrolase family 2 signature 470 485 8.9E-35 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_1225 fe81f11cc3160584997fa0bc625c7ca8 1040 ProSitePatterns PS00719 Glycosyl hydrolases family 2 signature 1. 392 417 - T 13-10-2018 IPR023230 Glycoside hydrolase, family 2, conserved site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_1225 fe81f11cc3160584997fa0bc625c7ca8 1040 Gene3D G3DSA:2.60.40.10 647 745 1.2E-18 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_1225 fe81f11cc3160584997fa0bc625c7ca8 1040 Gene3D G3DSA:3.20.20.80 341 642 5.8E-105 T 13-10-2018 Astex_1225 fe81f11cc3160584997fa0bc625c7ca8 1040 SMART SM01038 767 1036 2.3E-74 T 13-10-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_1225 fe81f11cc3160584997fa0bc625c7ca8 1040 Pfam PF02929 Beta galactosidase small chain 774 1035 5.1E-53 T 13-10-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_1225 fe81f11cc3160584997fa0bc625c7ca8 1040 ProSitePatterns PS00608 Glycosyl hydrolases family 2 acid/base catalyst. 470 484 - T 13-10-2018 IPR023232 Glycoside hydrolase, family 2, active site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_1225 fe81f11cc3160584997fa0bc625c7ca8 1040 Gene3D G3DSA:2.60.40.10 237 340 1.2E-22 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_1225 fe81f11cc3160584997fa0bc625c7ca8 1040 SUPERFAMILY SSF49303 639 746 1.22E-17 T 13-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily Astex_1225 fe81f11cc3160584997fa0bc625c7ca8 1040 SUPERFAMILY SSF51445 342 642 2.19E-82 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_1225 fe81f11cc3160584997fa0bc625c7ca8 1040 SUPERFAMILY SSF74650 763 1036 4.71E-62 T 13-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 Astex_1225 fe81f11cc3160584997fa0bc625c7ca8 1040 Pfam PF00703 Glycosyl hydrolases family 2 237 340 6.9E-12 T 13-10-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_1225 fe81f11cc3160584997fa0bc625c7ca8 1040 SUPERFAMILY SSF49785 25 236 4.39E-55 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_1225 fe81f11cc3160584997fa0bc625c7ca8 1040 SUPERFAMILY SSF49303 237 340 1.55E-20 T 13-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily Astex_1225 fe81f11cc3160584997fa0bc625c7ca8 1040 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 342 646 1.8E-94 T 13-10-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 Astex_3583 6025927557cc7b633cbc6ab4212ddbd3 499 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 5 482 6.7E-201 T 13-10-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00640+1.2.1.27|MetaCyc: PWY-5642|Reactome: R-HSA-70895 Astex_3583 6025927557cc7b633cbc6ab4212ddbd3 499 Gene3D G3DSA:3.40.605.10 23 459 2.6E-145 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 Astex_3583 6025927557cc7b633cbc6ab4212ddbd3 499 SUPERFAMILY SSF53720 2 483 4.84E-147 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 Astex_3583 6025927557cc7b633cbc6ab4212ddbd3 499 Pfam PF00171 Aldehyde dehydrogenase family 21 478 1.7E-136 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 Astex_3583 6025927557cc7b633cbc6ab4212ddbd3 499 Gene3D G3DSA:3.40.309.10 249 451 2.6E-145 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 Astex_1742 8732878a33061b9d7ea30b3ebea603f4 603 SUPERFAMILY SSF52016 386 587 2.35E-48 T 13-10-2018 Astex_1742 8732878a33061b9d7ea30b3ebea603f4 603 Pfam PF00920 Dehydratase family 49 575 7.2E-155 T 13-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Astex_1742 8732878a33061b9d7ea30b3ebea603f4 603 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 132 142 - T 13-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Astex_1742 8732878a33061b9d7ea30b3ebea603f4 603 Gene3D G3DSA:3.50.30.80 386 550 1.5E-36 T 13-10-2018 Astex_1742 8732878a33061b9d7ea30b3ebea603f4 603 SUPERFAMILY SSF143975 10 382 2.22E-117 T 13-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Astex_2102 c4db13aa753af6d04de32f568360a5e0 103 Pfam PF11011 Protein of unknown function (DUF2849) 2 87 3.0E-21 T 13-10-2018 IPR021270 Protein of unknown function DUF2849 Astex_3807 fc90df19564d52a775a6bfe5de75c8a7 90 Pfam PF00216 Bacterial DNA-binding protein 20 89 1.3E-19 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Astex_3807 fc90df19564d52a775a6bfe5de75c8a7 90 SMART SM00411 2 89 3.0E-17 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Astex_3807 fc90df19564d52a775a6bfe5de75c8a7 90 Gene3D G3DSA:4.10.520.10 9 90 4.3E-21 T 13-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 Astex_3807 fc90df19564d52a775a6bfe5de75c8a7 90 PRINTS PR01727 Prokaryotic integration host factor signature 73 87 6.3E-10 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Astex_3807 fc90df19564d52a775a6bfe5de75c8a7 90 PRINTS PR01727 Prokaryotic integration host factor signature 39 54 6.3E-10 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Astex_3807 fc90df19564d52a775a6bfe5de75c8a7 90 PRINTS PR01727 Prokaryotic integration host factor signature 57 70 6.3E-10 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Astex_3807 fc90df19564d52a775a6bfe5de75c8a7 90 SUPERFAMILY SSF47729 17 89 2.36E-18 T 13-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 Astex_3535 a8720129113b9e092cc183990c07f0f6 665 Gene3D G3DSA:2.60.40.10 35 111 3.9E-6 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_3535 a8720129113b9e092cc183990c07f0f6 665 SUPERFAMILY SSF49785 261 385 5.35E-25 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_3535 a8720129113b9e092cc183990c07f0f6 665 Gene3D G3DSA:3.40.50.1110 422 568 1.5E-10 T 13-10-2018 IPR036514 SGNH hydrolase superfamily Astex_3535 a8720129113b9e092cc183990c07f0f6 665 Gene3D G3DSA:3.40.50.1110 121 249 2.0E-9 T 13-10-2018 IPR036514 SGNH hydrolase superfamily Astex_3535 a8720129113b9e092cc183990c07f0f6 665 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 284 376 1.6E-6 T 13-10-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_3535 a8720129113b9e092cc183990c07f0f6 665 Pfam PF03629 Carbohydrate esterase, sialic acid-specific acetylesterase 447 542 1.7E-7 T 13-10-2018 IPR005181 Sialate O-acetylesterase domain Astex_3535 a8720129113b9e092cc183990c07f0f6 665 Pfam PF03629 Carbohydrate esterase, sialic acid-specific acetylesterase 120 245 4.6E-9 T 13-10-2018 IPR005181 Sialate O-acetylesterase domain Astex_3535 a8720129113b9e092cc183990c07f0f6 665 Gene3D G3DSA:2.60.120.260 250 396 7.1E-24 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_3535 a8720129113b9e092cc183990c07f0f6 665 SUPERFAMILY SSF52266 120 614 2.2E-57 T 13-10-2018 Astex_0817 7db6c9fbb172d8d22f1325372a8a0108 432 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 4 430 35.191 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Astex_0817 7db6c9fbb172d8d22f1325372a8a0108 432 Gene3D G3DSA:3.40.50.1980 31 235 3.1E-98 T 13-10-2018 Astex_0817 7db6c9fbb172d8d22f1325372a8a0108 432 PRINTS PR00083 Histidinol dehydrogenase signature 255 274 2.3E-73 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Astex_0817 7db6c9fbb172d8d22f1325372a8a0108 432 PRINTS PR00083 Histidinol dehydrogenase signature 364 382 2.3E-73 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Astex_0817 7db6c9fbb172d8d22f1325372a8a0108 432 PRINTS PR00083 Histidinol dehydrogenase signature 33 57 2.3E-73 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Astex_0817 7db6c9fbb172d8d22f1325372a8a0108 432 PRINTS PR00083 Histidinol dehydrogenase signature 201 226 2.3E-73 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Astex_0817 7db6c9fbb172d8d22f1325372a8a0108 432 PRINTS PR00083 Histidinol dehydrogenase signature 170 196 2.3E-73 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Astex_0817 7db6c9fbb172d8d22f1325372a8a0108 432 PRINTS PR00083 Histidinol dehydrogenase signature 107 134 2.3E-73 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Astex_0817 7db6c9fbb172d8d22f1325372a8a0108 432 PRINTS PR00083 Histidinol dehydrogenase signature 323 348 2.3E-73 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Astex_0817 7db6c9fbb172d8d22f1325372a8a0108 432 PRINTS PR00083 Histidinol dehydrogenase signature 233 254 2.3E-73 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Astex_0817 7db6c9fbb172d8d22f1325372a8a0108 432 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 33 429 1.7E-129 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Astex_0817 7db6c9fbb172d8d22f1325372a8a0108 432 PIRSF PIRSF000099 1 432 7.3E-133 T 13-10-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Astex_0817 7db6c9fbb172d8d22f1325372a8a0108 432 Gene3D G3DSA:3.40.50.1980 237 352 3.1E-98 T 13-10-2018 Astex_0817 7db6c9fbb172d8d22f1325372a8a0108 432 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 233 265 - T 13-10-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 Astex_0817 7db6c9fbb172d8d22f1325372a8a0108 432 SUPERFAMILY SSF53720 3 430 9.02E-70 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 Astex_0817 7db6c9fbb172d8d22f1325372a8a0108 432 Pfam PF00815 Histidinol dehydrogenase 24 430 4.0E-135 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 Astex_1619 23ca1cd3359a6c4120dbeb0527525b84 580 Pfam PF01019 Gamma-glutamyltranspeptidase 61 575 4.7E-140 T 13-10-2018 Astex_1619 23ca1cd3359a6c4120dbeb0527525b84 580 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 140 158 5.4E-31 T 13-10-2018 Astex_1619 23ca1cd3359a6c4120dbeb0527525b84 580 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 292 311 5.4E-31 T 13-10-2018 Astex_1619 23ca1cd3359a6c4120dbeb0527525b84 580 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 388 406 5.4E-31 T 13-10-2018 Astex_1619 23ca1cd3359a6c4120dbeb0527525b84 580 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 158 177 5.4E-31 T 13-10-2018 Astex_1619 23ca1cd3359a6c4120dbeb0527525b84 580 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 443 458 5.4E-31 T 13-10-2018 Astex_1619 23ca1cd3359a6c4120dbeb0527525b84 580 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 68 93 5.4E-31 T 13-10-2018 Astex_1619 23ca1cd3359a6c4120dbeb0527525b84 580 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 467 484 5.4E-31 T 13-10-2018 Astex_1619 23ca1cd3359a6c4120dbeb0527525b84 580 Gene3D G3DSA:3.60.20.40 388 580 7.1E-59 T 13-10-2018 Astex_1619 23ca1cd3359a6c4120dbeb0527525b84 580 Gene3D G3DSA:1.10.246.130 279 383 2.6E-30 T 13-10-2018 Astex_1619 23ca1cd3359a6c4120dbeb0527525b84 580 SUPERFAMILY SSF56235 35 580 5.98E-159 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Astex_0664 b0d1d73fc9052e083bfd1236e2d32f0a 343 Gene3D G3DSA:1.20.120.1460 255 326 3.3E-14 T 13-10-2018 Astex_0664 b0d1d73fc9052e083bfd1236e2d32f0a 343 PIRSF PIRSF006621 1 328 5.8E-75 T 13-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 Astex_0664 b0d1d73fc9052e083bfd1236e2d32f0a 343 Gene3D G3DSA:3.20.20.70 5 247 5.3E-76 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_0664 b0d1d73fc9052e083bfd1236e2d32f0a 343 SUPERFAMILY SSF51395 9 301 2.38E-71 T 13-10-2018 Astex_0664 b0d1d73fc9052e083bfd1236e2d32f0a 343 TIGRFAM TIGR00742 yjbN: tRNA dihydrouridine synthase A 9 322 7.0E-133 T 13-10-2018 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 Astex_0664 b0d1d73fc9052e083bfd1236e2d32f0a 343 Pfam PF01207 Dihydrouridine synthase (Dus) 11 312 8.5E-82 T 13-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 Astex_0664 b0d1d73fc9052e083bfd1236e2d32f0a 343 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 90 108 - T 13-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 Astex_0664 b0d1d73fc9052e083bfd1236e2d32f0a 343 Hamap MF_02041 tRNA-dihydrouridine(20/20a) synthase [dusA]. 3 323 50.349 T 13-10-2018 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 Astex_0713 0015c4eef685ad15ec7e59fa9a655756 562 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 381 529 4.5E-46 T 13-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 Astex_0713 0015c4eef685ad15ec7e59fa9a655756 562 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 7 172 2.5E-60 T 13-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 Astex_0713 0015c4eef685ad15ec7e59fa9a655756 562 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 192 327 2.8E-46 T 13-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 Astex_0713 0015c4eef685ad15ec7e59fa9a655756 562 Gene3D G3DSA:3.40.50.970 2 184 2.0E-72 T 13-10-2018 Astex_0713 0015c4eef685ad15ec7e59fa9a655756 562 SUPERFAMILY SSF52467 187 346 1.45E-57 T 13-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily Astex_0713 0015c4eef685ad15ec7e59fa9a655756 562 Gene3D G3DSA:3.40.50.970 354 558 1.8E-62 T 13-10-2018 Astex_0713 0015c4eef685ad15ec7e59fa9a655756 562 Gene3D G3DSA:3.40.50.1220 186 350 7.0E-56 T 13-10-2018 Astex_0713 0015c4eef685ad15ec7e59fa9a655756 562 SUPERFAMILY SSF52518 2 175 2.65E-63 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold Astex_0713 0015c4eef685ad15ec7e59fa9a655756 562 SUPERFAMILY SSF52518 363 553 7.33E-63 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold Astex_0713 0015c4eef685ad15ec7e59fa9a655756 562 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 418 437 - T 13-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 Astex_0713 0015c4eef685ad15ec7e59fa9a655756 562 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 7 553 1.8E-208 T 13-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 Astex_2616 f075e8f888d2367870ecc47e6adda570 560 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 26 553 4.7E-214 T 13-10-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005886|GO:0015990|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 Astex_2616 f075e8f888d2367870ecc47e6adda570 560 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 277 331 - T 13-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_2616 f075e8f888d2367870ecc47e6adda570 560 PRINTS PR01165 Cytochrome c oxidase subunit I signature 321 336 2.0E-142 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_2616 f075e8f888d2367870ecc47e6adda570 560 PRINTS PR01165 Cytochrome c oxidase subunit I signature 275 296 2.0E-142 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_2616 f075e8f888d2367870ecc47e6adda570 560 PRINTS PR01165 Cytochrome c oxidase subunit I signature 195 213 2.0E-142 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_2616 f075e8f888d2367870ecc47e6adda570 560 PRINTS PR01165 Cytochrome c oxidase subunit I signature 458 479 2.0E-142 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_2616 f075e8f888d2367870ecc47e6adda570 560 PRINTS PR01165 Cytochrome c oxidase subunit I signature 25 50 2.0E-142 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_2616 f075e8f888d2367870ecc47e6adda570 560 PRINTS PR01165 Cytochrome c oxidase subunit I signature 380 398 2.0E-142 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_2616 f075e8f888d2367870ecc47e6adda570 560 PRINTS PR01165 Cytochrome c oxidase subunit I signature 224 243 2.0E-142 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_2616 f075e8f888d2367870ecc47e6adda570 560 PRINTS PR01165 Cytochrome c oxidase subunit I signature 345 366 2.0E-142 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_2616 f075e8f888d2367870ecc47e6adda570 560 PRINTS PR01165 Cytochrome c oxidase subunit I signature 85 108 2.0E-142 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_2616 f075e8f888d2367870ecc47e6adda570 560 PRINTS PR01165 Cytochrome c oxidase subunit I signature 113 137 2.0E-142 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_2616 f075e8f888d2367870ecc47e6adda570 560 PRINTS PR01165 Cytochrome c oxidase subunit I signature 408 427 2.0E-142 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_2616 f075e8f888d2367870ecc47e6adda570 560 SUPERFAMILY SSF81442 23 555 7.85E-216 T 13-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_2616 f075e8f888d2367870ecc47e6adda570 560 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 34 499 2.4E-153 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_2616 f075e8f888d2367870ecc47e6adda570 560 Gene3D G3DSA:1.20.210.10 21 560 3.0E-244 T 13-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_1867 dd6a750c6fd9a27fa84c03f755ba1088 120 Pfam PF06170 Protein of unknown function (DUF983) 28 112 1.0E-25 T 13-10-2018 IPR009325 Protein of unknown function DUF983 Astex_1443 2dfa134f2d892e948e82904193049825 305 SUPERFAMILY SSF52540 5 226 1.25E-61 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1443 2dfa134f2d892e948e82904193049825 305 SMART SM00382 30 209 4.6E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_1443 2dfa134f2d892e948e82904193049825 305 Gene3D G3DSA:3.40.50.300 1 230 1.3E-65 T 13-10-2018 Astex_1443 2dfa134f2d892e948e82904193049825 305 Pfam PF00005 ABC transporter 22 163 1.4E-30 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_1443 2dfa134f2d892e948e82904193049825 305 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Astex_0262 a272fbf9ddaa904d01ca5a420eb48c19 289 PRINTS PR00126 ATP synthase gamma subunit signature 168 185 1.2E-29 T 13-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_0262 a272fbf9ddaa904d01ca5a420eb48c19 289 PRINTS PR00126 ATP synthase gamma subunit signature 267 288 1.2E-29 T 13-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_0262 a272fbf9ddaa904d01ca5a420eb48c19 289 PRINTS PR00126 ATP synthase gamma subunit signature 75 94 1.2E-29 T 13-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_0262 a272fbf9ddaa904d01ca5a420eb48c19 289 PRINTS PR00126 ATP synthase gamma subunit signature 236 255 1.2E-29 T 13-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_0262 a272fbf9ddaa904d01ca5a420eb48c19 289 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 289 5.8E-95 T 13-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_0262 a272fbf9ddaa904d01ca5a420eb48c19 289 Gene3D G3DSA:1.10.287.80 7 285 9.5E-90 T 13-10-2018 Astex_0262 a272fbf9ddaa904d01ca5a420eb48c19 289 SUPERFAMILY SSF52943 2 289 4.19E-82 T 13-10-2018 IPR035968 ATP synthase, F1 complex, gamma subunit superfamily GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_0262 a272fbf9ddaa904d01ca5a420eb48c19 289 Gene3D G3DSA:3.40.1380.10 61 208 9.5E-90 T 13-10-2018 Astex_0262 a272fbf9ddaa904d01ca5a420eb48c19 289 PIRSF PIRSF039089 1 289 5.8E-95 T 13-10-2018 Astex_0262 a272fbf9ddaa904d01ca5a420eb48c19 289 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 275 288 - T 13-10-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_0262 a272fbf9ddaa904d01ca5a420eb48c19 289 Pfam PF00231 ATP synthase 3 289 2.7E-87 T 13-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_0262 a272fbf9ddaa904d01ca5a420eb48c19 289 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 289 32.261 T 13-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_1413 7ada1115a080415c731e18ec650115f3 235 SMART SM00895 100 221 3.1E-21 T 13-10-2018 IPR011711 GntR, C-terminal Astex_1413 7ada1115a080415c731e18ec650115f3 235 Gene3D G3DSA:1.20.120.530 95 228 5.6E-27 T 13-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal Astex_1413 7ada1115a080415c731e18ec650115f3 235 SUPERFAMILY SSF48008 99 226 1.39E-26 T 13-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal Astex_1413 7ada1115a080415c731e18ec650115f3 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 31 45 3.2E-7 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Astex_1413 7ada1115a080415c731e18ec650115f3 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 61 3.2E-7 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Astex_1413 7ada1115a080415c731e18ec650115f3 235 Gene3D G3DSA:1.10.10.10 7 78 8.9E-14 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1413 7ada1115a080415c731e18ec650115f3 235 Pfam PF07729 FCD domain 100 219 4.2E-22 T 13-10-2018 IPR011711 GntR, C-terminal Astex_1413 7ada1115a080415c731e18ec650115f3 235 SUPERFAMILY SSF46785 3 75 1.06E-13 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_1413 7ada1115a080415c731e18ec650115f3 235 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 71 2.1E-12 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Astex_1413 7ada1115a080415c731e18ec650115f3 235 SMART SM00345 13 71 1.7E-7 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Astex_3032 efacf41574a0f83cd64c65713706a67c 342 Gene3D G3DSA:3.40.718.10 2 338 4.8E-104 T 13-10-2018 Astex_3032 efacf41574a0f83cd64c65713706a67c 342 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 41 331 1.2E-87 T 13-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 Astex_3032 efacf41574a0f83cd64c65713706a67c 342 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 9 334 9.8E-108 T 13-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 Astex_3032 efacf41574a0f83cd64c65713706a67c 342 SUPERFAMILY SSF53659 8 338 3.9E-93 T 13-10-2018 Astex_3032 efacf41574a0f83cd64c65713706a67c 342 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 6 338 34.522 T 13-10-2018 IPR037510 4-hydroxythreonine-4-phosphate dehydrogenase GO:0042823|GO:0050570 KEGG: 00750+1.1.1.262 Astex_3759 c826e4e4386671b3514f599738b5cc70 159 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 128 144 - T 13-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 Astex_3759 c826e4e4386671b3514f599738b5cc70 159 PIRSF PIRSF006092 6 159 9.5E-25 T 13-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 Astex_3759 c826e4e4386671b3514f599738b5cc70 159 Gene3D G3DSA:3.10.50.30 87 159 5.6E-21 T 13-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 Astex_3759 c826e4e4386671b3514f599738b5cc70 159 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 91 157 4.3E-20 T 13-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 Astex_3759 c826e4e4386671b3514f599738b5cc70 159 SUPERFAMILY SSF54534 90 150 1.96E-16 T 13-10-2018 Astex_1291 4f1ed396f2d7198fa894eeaebb3d95ae 226 Gene3D G3DSA:2.60.120.620 1 178 2.8E-45 T 13-10-2018 Astex_1291 4f1ed396f2d7198fa894eeaebb3d95ae 226 SMART SM00702 1 177 1.0E-25 T 13-10-2018 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 Astex_1291 4f1ed396f2d7198fa894eeaebb3d95ae 226 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 84 176 1.7E-14 T 13-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 Astex_1291 4f1ed396f2d7198fa894eeaebb3d95ae 226 SUPERFAMILY SSF51197 3 175 1.65E-7 T 13-10-2018 Astex_1291 4f1ed396f2d7198fa894eeaebb3d95ae 226 Hamap MF_00657 PKHD-type hydroxylase YbiX [ybiX]. 1 226 44.841 T 13-10-2018 IPR023550 PKHD-type hydroxylase GO:0016706|GO:0055114 Astex_1291 4f1ed396f2d7198fa894eeaebb3d95ae 226 Gene3D G3DSA:4.10.860.20 180 226 3.6E-20 T 13-10-2018 Astex_3188 183ad77330772e32e98d537f701c8d22 348 SUPERFAMILY SSF50129 5 170 1.03E-47 T 13-10-2018 IPR011032 GroES-like superfamily Astex_3188 183ad77330772e32e98d537f701c8d22 348 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 142 1.7E-22 T 13-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Astex_3188 183ad77330772e32e98d537f701c8d22 348 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 13-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 Astex_3188 183ad77330772e32e98d537f701c8d22 348 SUPERFAMILY SSF51735 148 310 8.23E-44 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_3188 183ad77330772e32e98d537f701c8d22 348 SMART SM00829 14 340 2.5E-5 T 13-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Astex_3188 183ad77330772e32e98d537f701c8d22 348 Gene3D G3DSA:3.90.180.10 13 340 2.7E-134 T 13-10-2018 Astex_3188 183ad77330772e32e98d537f701c8d22 348 Gene3D G3DSA:3.40.50.720 158 312 2.7E-134 T 13-10-2018 Astex_3188 183ad77330772e32e98d537f701c8d22 348 Pfam PF00107 Zinc-binding dehydrogenase 184 304 5.3E-23 T 13-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Astex_1793 fec876cd64f80e01380194d32e403f79 483 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 280 291 - T 13-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 Astex_1793 fec876cd64f80e01380194d32e403f79 483 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 252 259 - T 13-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 Astex_1793 fec876cd64f80e01380194d32e403f79 483 Gene3D G3DSA:3.40.309.10 259 449 4.7E-174 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 Astex_1793 fec876cd64f80e01380194d32e403f79 483 SUPERFAMILY SSF53720 21 478 3.53E-160 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 Astex_1793 fec876cd64f80e01380194d32e403f79 483 Pfam PF00171 Aldehyde dehydrogenase family 23 476 1.8E-163 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 Astex_1793 fec876cd64f80e01380194d32e403f79 483 Gene3D G3DSA:3.40.605.10 23 472 4.7E-174 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 Astex_0783 b33df35bee35491738f1587ec1ed3a11 272 SUPERFAMILY SSF51735 15 265 3.97E-59 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_0783 b33df35bee35491738f1587ec1ed3a11 272 Gene3D G3DSA:3.40.50.720 11 270 2.4E-52 T 13-10-2018 Astex_0783 b33df35bee35491738f1587ec1ed3a11 272 PIRSF PIRSF000094 11 270 1.6E-95 T 13-10-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 Astex_0783 b33df35bee35491738f1587ec1ed3a11 272 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 23 262 1.4E-76 T 13-10-2018 Astex_0783 b33df35bee35491738f1587ec1ed3a11 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 225 245 1.2E-9 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0783 b33df35bee35491738f1587ec1ed3a11 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 1.2E-9 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0783 b33df35bee35491738f1587ec1ed3a11 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 188 1.2E-9 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0783 b33df35bee35491738f1587ec1ed3a11 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 190 207 1.2E-9 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0783 b33df35bee35491738f1587ec1ed3a11 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 159 1.2E-9 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1499 54b94d5a1c4f7e2acf8120e41fd7eef5 132 Pfam PF07370 Protein of unknown function (DUF1489) 5 131 4.2E-44 T 13-10-2018 IPR008320 Uncharacterised conserved protein UCP032025 Astex_1499 54b94d5a1c4f7e2acf8120e41fd7eef5 132 PIRSF PIRSF032025 1 132 9.3E-44 T 13-10-2018 IPR008320 Uncharacterised conserved protein UCP032025 Astex_0802 18b0f00703183a0ab17abe39c5f454e0 296 SUPERFAMILY SSF48179 170 289 8.16E-26 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Astex_0802 18b0f00703183a0ab17abe39c5f454e0 296 Gene3D G3DSA:1.10.1040.10 168 294 5.7E-37 T 13-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 Astex_0802 18b0f00703183a0ab17abe39c5f454e0 296 SUPERFAMILY SSF51735 3 109 5.16E-13 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_0802 18b0f00703183a0ab17abe39c5f454e0 296 Pfam PF02558 Ketopantoate reductase PanE/ApbA 4 139 6.8E-24 T 13-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain Astex_0802 18b0f00703183a0ab17abe39c5f454e0 296 Gene3D G3DSA:3.40.50.720 1 167 3.2E-42 T 13-10-2018 Astex_0802 18b0f00703183a0ab17abe39c5f454e0 296 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 3 289 9.6E-58 T 13-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 Astex_0802 18b0f00703183a0ab17abe39c5f454e0 296 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 171 289 4.0E-26 T 13-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain Astex_0211 2c566c725f5510f0b10678e7d8b90d06 258 SUPERFAMILY SSF54292 28 128 4.33E-31 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 Astex_0211 2c566c725f5510f0b10678e7d8b90d06 258 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 32 251 1.8E-86 T 13-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 Astex_0211 2c566c725f5510f0b10678e7d8b90d06 258 Pfam PF13534 4Fe-4S dicluster domain 169 242 6.5E-10 T 13-10-2018 Astex_0211 2c566c725f5510f0b10678e7d8b90d06 258 Gene3D G3DSA:1.10.1060.10 129 257 2.0E-59 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Astex_0211 2c566c725f5510f0b10678e7d8b90d06 258 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 80 88 - T 13-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 Astex_0211 2c566c725f5510f0b10678e7d8b90d06 258 Gene3D G3DSA:3.10.20.30 18 128 4.5E-42 T 13-10-2018 IPR012675 Beta-grasp domain superfamily Astex_0211 2c566c725f5510f0b10678e7d8b90d06 258 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 31 132 1.8E-33 T 13-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 Astex_0211 2c566c725f5510f0b10678e7d8b90d06 258 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 170 181 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Astex_0211 2c566c725f5510f0b10678e7d8b90d06 258 SUPERFAMILY SSF46548 131 256 1.74E-37 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 Astex_3572 5b067ce5cbb29fc10be5155cac33f035 345 Gene3D G3DSA:2.115.10.20 26 341 2.4E-88 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Astex_3572 5b067ce5cbb29fc10be5155cac33f035 345 SUPERFAMILY SSF75005 35 341 1.43E-60 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Astex_3572 5b067ce5cbb29fc10be5155cac33f035 345 Pfam PF04616 Glycosyl hydrolases family 43 36 332 2.5E-63 T 13-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 Astex_3572 5b067ce5cbb29fc10be5155cac33f035 345 PIRSF PIRSF025414 3 344 1.5E-120 T 13-10-2018 IPR016828 Alpha-L-arabinofuranosidase KEGG: 00520+3.2.1.55 Astex_3685 e5c97bbcbe67db25ce31dabf0803e464 388 SUPERFAMILY SSF75005 45 380 5.76E-41 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Astex_3685 e5c97bbcbe67db25ce31dabf0803e464 388 Pfam PF04041 beta-1,4-mannooligosaccharide phosphorylase 134 381 5.7E-15 T 13-10-2018 IPR007184 Mannoside phosphorylase Astex_1913 87caf186c94a245758b7b41a62ce35bd 353 Gene3D G3DSA:1.10.260.40 11 66 6.7E-25 T 13-10-2018 Astex_1913 87caf186c94a245758b7b41a62ce35bd 353 SUPERFAMILY SSF47413 12 70 1.3E-19 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Astex_1913 87caf186c94a245758b7b41a62ce35bd 353 Pfam PF00356 Bacterial regulatory proteins, lacI family 14 59 2.9E-20 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Astex_1913 87caf186c94a245758b7b41a62ce35bd 353 Gene3D G3DSA:3.40.50.2300 67 317 1.5E-71 T 13-10-2018 Astex_1913 87caf186c94a245758b7b41a62ce35bd 353 Pfam PF13377 Periplasmic binding protein-like domain 179 344 2.4E-33 T 13-10-2018 Astex_1913 87caf186c94a245758b7b41a62ce35bd 353 SUPERFAMILY SSF53822 73 347 2.88E-67 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Astex_1913 87caf186c94a245758b7b41a62ce35bd 353 ProSitePatterns PS00356 LacI-type HTH domain signature. 15 33 - T 13-10-2018 Astex_1913 87caf186c94a245758b7b41a62ce35bd 353 Gene3D G3DSA:3.40.50.2300 171 300 1.5E-71 T 13-10-2018 Astex_1913 87caf186c94a245758b7b41a62ce35bd 353 SMART SM00354 12 82 5.3E-27 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Astex_1971 824c32abc12177aeff709c8a813cd067 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Astex_1971 824c32abc12177aeff709c8a813cd067 260 SUPERFAMILY SSF51735 4 259 4.03E-78 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_1971 824c32abc12177aeff709c8a813cd067 260 Pfam PF00106 short chain dehydrogenase 5 196 1.3E-55 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1971 824c32abc12177aeff709c8a813cd067 260 Gene3D G3DSA:3.40.50.720 1 260 3.6E-82 T 13-10-2018 Astex_1971 824c32abc12177aeff709c8a813cd067 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 2.9E-41 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1971 824c32abc12177aeff709c8a813cd067 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 2.9E-41 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1971 824c32abc12177aeff709c8a813cd067 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 2.9E-41 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1971 824c32abc12177aeff709c8a813cd067 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 2.9E-41 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1971 824c32abc12177aeff709c8a813cd067 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 2.9E-41 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1971 824c32abc12177aeff709c8a813cd067 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 2.9E-41 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1971 824c32abc12177aeff709c8a813cd067 260 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 5 259 4.9E-114 T 13-10-2018 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 Astex_1971 824c32abc12177aeff709c8a813cd067 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.3E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1971 824c32abc12177aeff709c8a813cd067 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.3E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1971 824c32abc12177aeff709c8a813cd067 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.3E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0271 b12df6fb604be541708533e99550d9e3 200 Pfam PF01047 MarR family 43 100 8.8E-12 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Astex_0271 b12df6fb604be541708533e99550d9e3 200 Gene3D G3DSA:1.10.10.10 10 156 1.3E-31 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_0271 b12df6fb604be541708533e99550d9e3 200 PRINTS PR00598 Bacterial regulatory protein MarR family signature 126 146 2.6E-9 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Astex_0271 b12df6fb604be541708533e99550d9e3 200 PRINTS PR00598 Bacterial regulatory protein MarR family signature 96 112 2.6E-9 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Astex_0271 b12df6fb604be541708533e99550d9e3 200 PRINTS PR00598 Bacterial regulatory protein MarR family signature 60 76 2.6E-9 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Astex_0271 b12df6fb604be541708533e99550d9e3 200 PRINTS PR00598 Bacterial regulatory protein MarR family signature 77 92 2.6E-9 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Astex_0271 b12df6fb604be541708533e99550d9e3 200 SMART SM00347 36 136 5.1E-20 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Astex_0271 b12df6fb604be541708533e99550d9e3 200 SUPERFAMILY SSF46785 13 152 6.94E-29 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_0965 53578d84cd28eb6d86b62eac99f4d43a 450 Hamap MF_01465 Protein translocase subunit SecY [secY]. 14 439 28.569 T 13-10-2018 IPR026593 Protein translocase subunit SecY Astex_0965 53578d84cd28eb6d86b62eac99f4d43a 450 Gene3D G3DSA:1.10.3370.10 12 435 3.3E-152 T 13-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Astex_0965 53578d84cd28eb6d86b62eac99f4d43a 450 SUPERFAMILY SSF103491 15 430 2.75E-123 T 13-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Astex_0965 53578d84cd28eb6d86b62eac99f4d43a 450 Pfam PF00344 SecY translocase 81 423 3.5E-111 T 13-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Astex_0965 53578d84cd28eb6d86b62eac99f4d43a 450 PRINTS PR00303 Preprotein translocase SecY subunit signature 273 292 1.3E-95 T 13-10-2018 Astex_0965 53578d84cd28eb6d86b62eac99f4d43a 450 PRINTS PR00303 Preprotein translocase SecY subunit signature 155 180 1.3E-95 T 13-10-2018 Astex_0965 53578d84cd28eb6d86b62eac99f4d43a 450 PRINTS PR00303 Preprotein translocase SecY subunit signature 376 394 1.3E-95 T 13-10-2018 Astex_0965 53578d84cd28eb6d86b62eac99f4d43a 450 PRINTS PR00303 Preprotein translocase SecY subunit signature 408 426 1.3E-95 T 13-10-2018 Astex_0965 53578d84cd28eb6d86b62eac99f4d43a 450 PRINTS PR00303 Preprotein translocase SecY subunit signature 27 45 1.3E-95 T 13-10-2018 Astex_0965 53578d84cd28eb6d86b62eac99f4d43a 450 PRINTS PR00303 Preprotein translocase SecY subunit signature 321 343 1.3E-95 T 13-10-2018 Astex_0965 53578d84cd28eb6d86b62eac99f4d43a 450 PRINTS PR00303 Preprotein translocase SecY subunit signature 79 99 1.3E-95 T 13-10-2018 Astex_0965 53578d84cd28eb6d86b62eac99f4d43a 450 PRINTS PR00303 Preprotein translocase SecY subunit signature 181 204 1.3E-95 T 13-10-2018 Astex_0965 53578d84cd28eb6d86b62eac99f4d43a 450 PRINTS PR00303 Preprotein translocase SecY subunit signature 121 144 1.3E-95 T 13-10-2018 Astex_0965 53578d84cd28eb6d86b62eac99f4d43a 450 ProSitePatterns PS00756 Protein secY signature 2. 174 191 - T 13-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Astex_0965 53578d84cd28eb6d86b62eac99f4d43a 450 PIRSF PIRSF004557 1 447 1.1E-121 T 13-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Astex_0965 53578d84cd28eb6d86b62eac99f4d43a 450 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 25 434 5.3E-124 T 13-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Astex_2927 e100ce080b4485aa99969d3536ab4525 174 Gene3D G3DSA:1.10.1660.10 6 79 7.4E-20 T 13-10-2018 Astex_2927 e100ce080b4485aa99969d3536ab4525 174 Pfam PF13411 MerR HTH family regulatory protein 10 76 2.2E-20 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Astex_2927 e100ce080b4485aa99969d3536ab4525 174 SMART SM00422 10 79 5.7E-4 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Astex_2927 e100ce080b4485aa99969d3536ab4525 174 SUPERFAMILY SSF46955 10 77 2.33E-13 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily Astex_2169 2ae9ca1f573bc25770e9eb6e1b2451e5 446 TIGRFAM TIGR02629 L_rham_iso_rhiz: L-rhamnose catabolism isomerase 25 436 7.3E-200 T 13-10-2018 IPR013451 L-rhamnose catabolism isomerase Astex_2169 2ae9ca1f573bc25770e9eb6e1b2451e5 446 SUPERFAMILY SSF51658 66 420 4.98E-80 T 13-10-2018 IPR036237 Xylose isomerase-like superfamily Astex_2169 2ae9ca1f573bc25770e9eb6e1b2451e5 446 Pfam PF01261 Xylose isomerase-like TIM barrel 114 303 5.3E-8 T 13-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain Astex_2169 2ae9ca1f573bc25770e9eb6e1b2451e5 446 ProDom PD042532 ISOMERASE L-RHAMNOSE METAL-BINDING METABOLISM RHAMNOSE MANGANESE ENZYME KINASE 3D-STRUCTURE RHAA/RHAB 41 307 1.0E-4 T 13-10-2018 Astex_2169 2ae9ca1f573bc25770e9eb6e1b2451e5 446 Gene3D G3DSA:3.20.20.150 17 437 4.1E-137 T 13-10-2018 Astex_2412 b6acfc8a0329dc35e8b74bb0ace1de65 454 Gene3D G3DSA:1.10.490.10 4 163 5.5E-41 T 13-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 Astex_2412 b6acfc8a0329dc35e8b74bb0ace1de65 454 Gene3D G3DSA:1.10.287.950 172 452 2.0E-48 T 13-10-2018 Astex_2412 b6acfc8a0329dc35e8b74bb0ace1de65 454 SMART SM00283 202 449 2.4E-43 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_2412 b6acfc8a0329dc35e8b74bb0ace1de65 454 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 256 420 4.5E-27 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_2412 b6acfc8a0329dc35e8b74bb0ace1de65 454 SUPERFAMILY SSF58104 172 448 1.07E-54 T 13-10-2018 Astex_2412 b6acfc8a0329dc35e8b74bb0ace1de65 454 SUPERFAMILY SSF46458 10 163 4.14E-28 T 13-10-2018 IPR009050 Globin-like superfamily Astex_2412 b6acfc8a0329dc35e8b74bb0ace1de65 454 Pfam PF11563 Protoglobin 16 171 7.6E-34 T 13-10-2018 Astex_2086 ad7edb66d621f507e8ea11d167ade7fb 321 SUPERFAMILY SSF161111 22 221 3.27E-43 T 13-10-2018 IPR027469 Cation efflux transmembrane domain superfamily Astex_2086 ad7edb66d621f507e8ea11d167ade7fb 321 Gene3D G3DSA:3.30.70.1350 221 302 1.5E-23 T 13-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 Astex_2086 ad7edb66d621f507e8ea11d167ade7fb 321 Gene3D G3DSA:1.20.1510.10 22 220 6.9E-46 T 13-10-2018 IPR027469 Cation efflux transmembrane domain superfamily Astex_2086 ad7edb66d621f507e8ea11d167ade7fb 321 Pfam PF16916 Dimerisation domain of Zinc Transporter 225 300 6.7E-22 T 13-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain Astex_2086 ad7edb66d621f507e8ea11d167ade7fb 321 SUPERFAMILY SSF160240 224 301 4.32E-20 T 13-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 Astex_2086 ad7edb66d621f507e8ea11d167ade7fb 321 Pfam PF01545 Cation efflux family 29 220 1.4E-29 T 13-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 Astex_2086 ad7edb66d621f507e8ea11d167ade7fb 321 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 26 300 1.2E-57 T 13-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 Astex_1262 77440b4d1d73c011d7a2a1b155bc7a03 157 Pfam PF08670 MEKHLA domain 12 156 3.1E-50 T 13-10-2018 IPR013978 MEKHLA Astex_1374 5c4abd891e017d82e430d5538c067b55 1080 Gene3D G3DSA:3.40.50.2300 961 1080 2.4E-24 T 13-10-2018 Astex_1374 5c4abd891e017d82e430d5538c067b55 1080 Pfam PF08448 PAS fold 329 439 2.4E-17 T 13-10-2018 IPR013656 PAS fold-4 Astex_1374 5c4abd891e017d82e430d5538c067b55 1080 Pfam PF08448 PAS fold 187 296 7.5E-9 T 13-10-2018 IPR013656 PAS fold-4 Astex_1374 5c4abd891e017d82e430d5538c067b55 1080 Gene3D G3DSA:3.30.565.10 775 940 3.5E-42 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_1374 5c4abd891e017d82e430d5538c067b55 1080 Gene3D G3DSA:3.30.450.20 309 456 1.9E-14 T 13-10-2018 Astex_1374 5c4abd891e017d82e430d5538c067b55 1080 Gene3D G3DSA:3.30.450.20 179 308 3.6E-31 T 13-10-2018 Astex_1374 5c4abd891e017d82e430d5538c067b55 1080 Gene3D G3DSA:3.30.450.20 56 178 5.8E-17 T 13-10-2018 Astex_1374 5c4abd891e017d82e430d5538c067b55 1080 SMART SM00091 574 645 240.0 T 13-10-2018 IPR000014 PAS domain Astex_1374 5c4abd891e017d82e430d5538c067b55 1080 SMART SM00091 322 392 270.0 T 13-10-2018 IPR000014 PAS domain Astex_1374 5c4abd891e017d82e430d5538c067b55 1080 SMART SM00091 454 520 2.4E-8 T 13-10-2018 IPR000014 PAS domain Astex_1374 5c4abd891e017d82e430d5538c067b55 1080 SMART SM00091 181 246 0.98 T 13-10-2018 IPR000014 PAS domain Astex_1374 5c4abd891e017d82e430d5538c067b55 1080 SUPERFAMILY SSF55785 461 560 7.25E-20 T 13-10-2018 IPR035965 PAS domain superfamily Astex_1374 5c4abd891e017d82e430d5538c067b55 1080 SUPERFAMILY SSF52172 963 1079 7.4E-26 T 13-10-2018 IPR011006 CheY-like superfamily Astex_1374 5c4abd891e017d82e430d5538c067b55 1080 SMART SM00448 961 1073 9.6E-18 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1374 5c4abd891e017d82e430d5538c067b55 1080 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 816 936 9.1E-19 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_1374 5c4abd891e017d82e430d5538c067b55 1080 Gene3D G3DSA:2.10.70.100 649 694 4.0E-13 T 13-10-2018 Astex_1374 5c4abd891e017d82e430d5538c067b55 1080 Pfam PF13426 PAS domain 78 167 0.03 T 13-10-2018 IPR000014 PAS domain Astex_1374 5c4abd891e017d82e430d5538c067b55 1080 SUPERFAMILY SSF55785 586 694 1.2E-14 T 13-10-2018 IPR035965 PAS domain superfamily Astex_1374 5c4abd891e017d82e430d5538c067b55 1080 Gene3D G3DSA:3.30.450.20 457 573 3.1E-20 T 13-10-2018 Astex_1374 5c4abd891e017d82e430d5538c067b55 1080 SUPERFAMILY SSF55874 765 936 1.57E-39 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_1374 5c4abd891e017d82e430d5538c067b55 1080 Gene3D G3DSA:1.10.287.130 699 772 3.1E-21 T 13-10-2018 Astex_1374 5c4abd891e017d82e430d5538c067b55 1080 Pfam PF00072 Response regulator receiver domain 963 1073 8.0E-16 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1374 5c4abd891e017d82e430d5538c067b55 1080 PRINTS PR00344 Bacterial sensor protein C-terminal signature 898 916 3.6E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1374 5c4abd891e017d82e430d5538c067b55 1080 PRINTS PR00344 Bacterial sensor protein C-terminal signature 867 881 3.6E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1374 5c4abd891e017d82e430d5538c067b55 1080 PRINTS PR00344 Bacterial sensor protein C-terminal signature 922 935 3.6E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1374 5c4abd891e017d82e430d5538c067b55 1080 PRINTS PR00344 Bacterial sensor protein C-terminal signature 885 895 3.6E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1374 5c4abd891e017d82e430d5538c067b55 1080 SMART SM00086 126 169 2.3 T 13-10-2018 IPR001610 PAC motif Astex_1374 5c4abd891e017d82e430d5538c067b55 1080 SMART SM00086 255 296 450.0 T 13-10-2018 IPR001610 PAC motif Astex_1374 5c4abd891e017d82e430d5538c067b55 1080 SMART SM00086 526 562 410.0 T 13-10-2018 IPR001610 PAC motif Astex_1374 5c4abd891e017d82e430d5538c067b55 1080 SMART SM00086 651 692 2.1E-5 T 13-10-2018 IPR001610 PAC motif Astex_1374 5c4abd891e017d82e430d5538c067b55 1080 Pfam PF00989 PAS fold 455 543 6.0E-11 T 13-10-2018 IPR013767 PAS fold GO:0006355 Astex_1374 5c4abd891e017d82e430d5538c067b55 1080 SUPERFAMILY SSF55785 199 304 1.2E-8 T 13-10-2018 IPR035965 PAS domain superfamily Astex_1374 5c4abd891e017d82e430d5538c067b55 1080 SMART SM00387 815 938 1.4E-27 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_1374 5c4abd891e017d82e430d5538c067b55 1080 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 457 568 1.5E-12 T 13-10-2018 IPR000014 PAS domain Astex_1374 5c4abd891e017d82e430d5538c067b55 1080 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 627 699 1.2E-6 T 13-10-2018 IPR000014 PAS domain Astex_1374 5c4abd891e017d82e430d5538c067b55 1080 SMART SM00388 707 774 1.1E-7 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_1374 5c4abd891e017d82e430d5538c067b55 1080 Pfam PF00512 His Kinase A (phospho-acceptor) domain 708 771 2.8E-9 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_1374 5c4abd891e017d82e430d5538c067b55 1080 Gene3D G3DSA:3.30.450.20 574 644 5.5E-8 T 13-10-2018 Astex_1374 5c4abd891e017d82e430d5538c067b55 1080 Pfam PF08447 PAS fold 623 685 6.4E-13 T 13-10-2018 IPR013655 PAS fold-3 GO:0005515 Astex_1374 5c4abd891e017d82e430d5538c067b55 1080 SUPERFAMILY SSF47384 698 771 3.92E-10 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Astex_1374 5c4abd891e017d82e430d5538c067b55 1080 SUPERFAMILY SSF55785 292 430 9.25E-9 T 13-10-2018 IPR035965 PAS domain superfamily Astex_3661 504e35509d95e51bf1f49a8acccf3457 363 Gene3D G3DSA:2.40.30.170 51 282 1.0E-57 T 13-10-2018 Astex_3661 504e35509d95e51bf1f49a8acccf3457 363 Gene3D G3DSA:2.40.50.100 63 209 1.0E-57 T 13-10-2018 Astex_3661 504e35509d95e51bf1f49a8acccf3457 363 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 64 263 1.6E-10 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain Astex_3661 504e35509d95e51bf1f49a8acccf3457 363 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 44 357 4.2E-60 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 Astex_3661 504e35509d95e51bf1f49a8acccf3457 363 Gene3D G3DSA:2.40.420.20 283 355 1.0E-57 T 13-10-2018 Astex_3661 504e35509d95e51bf1f49a8acccf3457 363 Gene3D G3DSA:1.10.287.470 97 169 1.0E-57 T 13-10-2018 Astex_3661 504e35509d95e51bf1f49a8acccf3457 363 SUPERFAMILY SSF111369 54 261 3.27E-15 T 13-10-2018 Astex_1490 ef84236b3023c6c4947fdc8b739d19a2 348 SUPERFAMILY SSF50494 128 328 8.19E-24 T 13-10-2018 IPR009003 Peptidase S1, PA clan Astex_1490 ef84236b3023c6c4947fdc8b739d19a2 348 Gene3D G3DSA:2.40.10.10 209 336 2.6E-9 T 13-10-2018 Astex_1490 ef84236b3023c6c4947fdc8b739d19a2 348 Pfam PF13365 Trypsin-like peptidase domain 141 289 5.9E-15 T 13-10-2018 Astex_1490 ef84236b3023c6c4947fdc8b739d19a2 348 Gene3D G3DSA:2.40.10.10 114 198 1.4E-5 T 13-10-2018 Astex_1915 f9688e7d518c7649fdf2b84ec7cce9e4 649 Pfam PF03629 Carbohydrate esterase, sialic acid-specific acetylesterase 107 228 6.3E-8 T 13-10-2018 IPR005181 Sialate O-acetylesterase domain Astex_1915 f9688e7d518c7649fdf2b84ec7cce9e4 649 Pfam PF03629 Carbohydrate esterase, sialic acid-specific acetylesterase 422 541 3.0E-13 T 13-10-2018 IPR005181 Sialate O-acetylesterase domain Astex_1915 f9688e7d518c7649fdf2b84ec7cce9e4 649 Pfam PF13364 Beta-galactosidase jelly roll domain 261 364 8.7E-6 T 13-10-2018 IPR025300 Beta-galactosidase jelly roll domain KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024096|Reactome: R-HSA-2206308|Reactome: R-HSA-4085001|Reactome: R-HSA-6798695 Astex_1915 f9688e7d518c7649fdf2b84ec7cce9e4 649 Gene3D G3DSA:2.60.120.260 242 383 4.3E-25 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_1915 f9688e7d518c7649fdf2b84ec7cce9e4 649 Gene3D G3DSA:3.40.50.1110 405 555 5.6E-14 T 13-10-2018 IPR036514 SGNH hydrolase superfamily Astex_1915 f9688e7d518c7649fdf2b84ec7cce9e4 649 Gene3D G3DSA:3.40.50.1110 108 241 3.4E-7 T 13-10-2018 IPR036514 SGNH hydrolase superfamily Astex_1915 f9688e7d518c7649fdf2b84ec7cce9e4 649 SUPERFAMILY SSF52266 106 604 1.01E-61 T 13-10-2018 Astex_1915 f9688e7d518c7649fdf2b84ec7cce9e4 649 SUPERFAMILY SSF49785 231 375 8.51E-23 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_2039 525cfed5a15a5071abff1d797fb77ffc 358 Pfam PF11899 Protein of unknown function (DUF3419) 12 316 1.1E-37 T 13-10-2018 IPR021829 Protein of unknown function DUF3419 Astex_1090 219776511e52a4da6807031e57aa3be3 697 SMART SM01060 34 422 9.4E-268 T 13-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Astex_1090 219776511e52a4da6807031e57aa3be3 697 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 364 372 - T 13-10-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Astex_1090 219776511e52a4da6807031e57aa3be3 697 ProSitePatterns PS00438 Catalase proximal active site signature. 70 86 - T 13-10-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Astex_1090 219776511e52a4da6807031e57aa3be3 697 Pfam PF06628 Catalase-related immune-responsive 457 519 9.9E-21 T 13-10-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Astex_1090 219776511e52a4da6807031e57aa3be3 697 Pfam PF00199 Catalase 34 418 5.0E-176 T 13-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Astex_1090 219776511e52a4da6807031e57aa3be3 697 PIRSF PIRSF038927 8 697 1.8E-284 T 13-10-2018 IPR024712 Catalase, mono-functional, haem-containing, clade 2 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Astex_1090 219776511e52a4da6807031e57aa3be3 697 Gene3D G3DSA:2.40.180.10 3 442 2.3E-198 T 13-10-2018 IPR037060 Catalase core domain superfamily GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Astex_1090 219776511e52a4da6807031e57aa3be3 697 SUPERFAMILY SSF52317 553 687 1.98E-11 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Astex_1090 219776511e52a4da6807031e57aa3be3 697 Gene3D G3DSA:1.20.1370.20 453 548 2.0E-30 T 13-10-2018 Astex_1090 219776511e52a4da6807031e57aa3be3 697 Gene3D G3DSA:3.40.50.880 549 695 1.6E-23 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Astex_1090 219776511e52a4da6807031e57aa3be3 697 SUPERFAMILY SSF56634 17 527 3.01E-211 T 13-10-2018 IPR020835 Catalase superfamily GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Astex_1090 219776511e52a4da6807031e57aa3be3 697 PRINTS PR00067 Catalase signature 131 148 2.6E-69 T 13-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Astex_1090 219776511e52a4da6807031e57aa3be3 697 PRINTS PR00067 Catalase signature 319 346 2.6E-69 T 13-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Astex_1090 219776511e52a4da6807031e57aa3be3 697 PRINTS PR00067 Catalase signature 47 70 2.6E-69 T 13-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Astex_1090 219776511e52a4da6807031e57aa3be3 697 PRINTS PR00067 Catalase signature 110 128 2.6E-69 T 13-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Astex_1090 219776511e52a4da6807031e57aa3be3 697 PRINTS PR00067 Catalase signature 351 377 2.6E-69 T 13-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Astex_1090 219776511e52a4da6807031e57aa3be3 697 PRINTS PR00067 Catalase signature 150 168 2.6E-69 T 13-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Astex_1829 1fc332379f286029d7b48fcb5b5e7d99 231 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 38 223 4.5E-65 T 13-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 Astex_1829 1fc332379f286029d7b48fcb5b5e7d99 231 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 43 227 26.651 T 13-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 Astex_1829 1fc332379f286029d7b48fcb5b5e7d99 231 Pfam PF01926 50S ribosome-binding GTPase 57 175 2.9E-20 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Astex_1829 1fc332379f286029d7b48fcb5b5e7d99 231 SUPERFAMILY SSF52540 40 225 3.26E-35 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1829 1fc332379f286029d7b48fcb5b5e7d99 231 Gene3D G3DSA:3.40.50.300 32 229 3.7E-53 T 13-10-2018 Astex_2864 b9aa1634bba90e4e2014d5aa31683e24 337 SUPERFAMILY SSF47648 5 72 4.58E-17 T 13-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 Astex_2864 b9aa1634bba90e4e2014d5aa31683e24 337 Gene3D G3DSA:3.40.1030.10 73 337 1.0E-103 T 13-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 Astex_2864 b9aa1634bba90e4e2014d5aa31683e24 337 SUPERFAMILY SSF52418 74 332 1.31E-90 T 13-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 Astex_2864 b9aa1634bba90e4e2014d5aa31683e24 337 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 10 333 2.5E-114 T 13-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 Astex_2864 b9aa1634bba90e4e2014d5aa31683e24 337 Gene3D G3DSA:1.20.970.10 8 71 9.4E-19 T 13-10-2018 Astex_2864 b9aa1634bba90e4e2014d5aa31683e24 337 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 7 334 36.949 T 13-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 Astex_2864 b9aa1634bba90e4e2014d5aa31683e24 337 Pfam PF00591 Glycosyl transferase family, a/b domain 76 325 4.6E-95 T 13-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 Astex_2864 b9aa1634bba90e4e2014d5aa31683e24 337 Pfam PF02885 Glycosyl transferase family, helical bundle domain 6 68 1.3E-18 T 13-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 Astex_3409 9e1f0ccbe75974bcebdff3802873b55f 228 SUPERFAMILY SSF56935 19 182 7.33E-7 T 13-10-2018 Astex_3409 9e1f0ccbe75974bcebdff3802873b55f 228 Pfam PF09694 Bacterial protein of unknown function (Gcw_chp) 24 209 2.9E-7 T 13-10-2018 IPR010239 Conserved hypothetical protein CHP02001 Astex_1516 bf7c41f5fc5a1eb3c3da39b9b8abdf20 454 Gene3D G3DSA:2.160.10.10 254 427 1.2E-46 T 13-10-2018 Astex_1516 bf7c41f5fc5a1eb3c3da39b9b8abdf20 454 Pfam PF12804 MobA-like NTP transferase domain 9 138 5.0E-19 T 13-10-2018 IPR025877 MobA-like NTP transferase Astex_1516 bf7c41f5fc5a1eb3c3da39b9b8abdf20 454 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 8 439 1.3E-144 T 13-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 Astex_1516 bf7c41f5fc5a1eb3c3da39b9b8abdf20 454 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 6 439 36.874 T 13-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 Astex_1516 bf7c41f5fc5a1eb3c3da39b9b8abdf20 454 SUPERFAMILY SSF53448 7 257 5.41E-52 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_1516 bf7c41f5fc5a1eb3c3da39b9b8abdf20 454 Gene3D G3DSA:3.90.550.10 1 253 3.1E-59 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_1516 bf7c41f5fc5a1eb3c3da39b9b8abdf20 454 SUPERFAMILY SSF51161 255 424 1.95E-44 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily Astex_1516 bf7c41f5fc5a1eb3c3da39b9b8abdf20 454 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 382 416 2.6E-7 T 13-10-2018 IPR001451 Hexapeptide repeat Astex_1516 bf7c41f5fc5a1eb3c3da39b9b8abdf20 454 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 269 303 8.5E-4 T 13-10-2018 IPR001451 Hexapeptide repeat Astex_1516 bf7c41f5fc5a1eb3c3da39b9b8abdf20 454 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 309 338 2.3E-6 T 13-10-2018 IPR001451 Hexapeptide repeat Astex_3485 6350116bbe549a2108e5a61b7afb435e 482 Pfam PF13671 AAA domain 327 454 2.0E-21 T 13-10-2018 Astex_3485 6350116bbe549a2108e5a61b7afb435e 482 SUPERFAMILY SSF52540 321 456 4.58E-16 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_3485 6350116bbe549a2108e5a61b7afb435e 482 Gene3D G3DSA:3.90.1200.10 94 227 1.4E-5 T 13-10-2018 Astex_3485 6350116bbe549a2108e5a61b7afb435e 482 SUPERFAMILY SSF56112 32 291 8.16E-23 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily Astex_3485 6350116bbe549a2108e5a61b7afb435e 482 Gene3D G3DSA:3.40.50.300 324 477 4.0E-27 T 13-10-2018 Astex_3485 6350116bbe549a2108e5a61b7afb435e 482 Pfam PF01636 Phosphotransferase enzyme family 116 251 2.3E-10 T 13-10-2018 IPR002575 Aminoglycoside phosphotransferase Astex_0187 0282043fc3f833711f2f00b489447219 760 Gene3D G3DSA:3.30.230.70 241 561 3.7E-118 T 13-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 Astex_0187 0282043fc3f833711f2f00b489447219 760 SUPERFAMILY SSF55666 155 244 2.95E-29 T 13-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 Astex_0187 0282043fc3f833711f2f00b489447219 760 Pfam PF01138 3' exoribonuclease family, domain 1 336 468 7.1E-21 T 13-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 Astex_0187 0282043fc3f833711f2f00b489447219 760 Pfam PF01138 3' exoribonuclease family, domain 1 24 154 1.4E-23 T 13-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 Astex_0187 0282043fc3f833711f2f00b489447219 760 SUPERFAMILY SSF46915 237 337 4.71E-16 T 13-10-2018 IPR036456 Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 Astex_0187 0282043fc3f833711f2f00b489447219 760 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 20 703 0.0 T 13-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 Astex_0187 0282043fc3f833711f2f00b489447219 760 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 251 331 5.5E-16 T 13-10-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 Astex_0187 0282043fc3f833711f2f00b489447219 760 SMART SM00316 632 702 1.5E-21 T 13-10-2018 IPR022967 RNA-binding domain, S1 Astex_0187 0282043fc3f833711f2f00b489447219 760 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 13 705 30.535 T 13-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 Astex_0187 0282043fc3f833711f2f00b489447219 760 SUPERFAMILY SSF50249 632 716 3.98E-20 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Astex_0187 0282043fc3f833711f2f00b489447219 760 Pfam PF03725 3' exoribonuclease family, domain 2 472 540 2.6E-4 T 13-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 Astex_0187 0282043fc3f833711f2f00b489447219 760 Pfam PF03725 3' exoribonuclease family, domain 2 157 220 1.4E-14 T 13-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 Astex_0187 0282043fc3f833711f2f00b489447219 760 Gene3D G3DSA:3.30.1370.10 562 633 8.6E-18 T 13-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 Astex_0187 0282043fc3f833711f2f00b489447219 760 SMART SM00322 564 629 1.8E-10 T 13-10-2018 IPR004087 K Homology domain GO:0003676 Astex_0187 0282043fc3f833711f2f00b489447219 760 Pfam PF00013 KH domain 568 625 6.1E-9 T 13-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 Astex_0187 0282043fc3f833711f2f00b489447219 760 Gene3D G3DSA:2.40.50.140 634 706 1.5E-28 T 13-10-2018 Astex_0187 0282043fc3f833711f2f00b489447219 760 SUPERFAMILY SSF54791 567 652 3.79E-21 T 13-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 Astex_0187 0282043fc3f833711f2f00b489447219 760 Gene3D G3DSA:3.30.230.70 5 240 5.0E-88 T 13-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 Astex_0187 0282043fc3f833711f2f00b489447219 760 SUPERFAMILY SSF55666 462 560 7.71E-28 T 13-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 Astex_0187 0282043fc3f833711f2f00b489447219 760 Pfam PF00575 S1 RNA binding domain 630 702 1.9E-17 T 13-10-2018 IPR003029 S1 domain GO:0003676 Astex_0187 0282043fc3f833711f2f00b489447219 760 SUPERFAMILY SSF54211 8 154 8.1E-52 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Astex_0187 0282043fc3f833711f2f00b489447219 760 SUPERFAMILY SSF54211 315 504 1.97E-48 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Astex_0187 0282043fc3f833711f2f00b489447219 760 PIRSF PIRSF005499 11 734 3.7E-298 T 13-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 Astex_2667 76b5b48652d5744d9336af1e40c3524d 87 Pfam PF05101 Type IV secretory pathway, VirB3-like protein 9 77 1.2E-12 T 13-10-2018 IPR007792 Type IV secretion system, VirB3 / TrbD / AvhB Astex_2667 76b5b48652d5744d9336af1e40c3524d 87 PIRSF PIRSF017854 1 87 2.6E-30 T 13-10-2018 IPR016704 Conjugal transfer, TrbD Astex_1143 dc871e79db4cf86fb108722209206c34 289 PRINTS PR00603 Cytochrome C1 signature 188 199 6.6E-44 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 Astex_1143 dc871e79db4cf86fb108722209206c34 289 PRINTS PR00603 Cytochrome C1 signature 235 254 6.6E-44 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 Astex_1143 dc871e79db4cf86fb108722209206c34 289 PRINTS PR00603 Cytochrome C1 signature 150 174 6.6E-44 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 Astex_1143 dc871e79db4cf86fb108722209206c34 289 PRINTS PR00603 Cytochrome C1 signature 215 234 6.6E-44 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 Astex_1143 dc871e79db4cf86fb108722209206c34 289 PRINTS PR00603 Cytochrome C1 signature 41 60 6.6E-44 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 Astex_1143 dc871e79db4cf86fb108722209206c34 289 PRINTS PR00603 Cytochrome C1 signature 254 269 6.6E-44 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 Astex_1143 dc871e79db4cf86fb108722209206c34 289 SUPERFAMILY SSF46626 36 252 8.42E-56 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Astex_1143 dc871e79db4cf86fb108722209206c34 289 Pfam PF02167 Cytochrome C1 family 43 286 5.7E-86 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 Astex_1143 dc871e79db4cf86fb108722209206c34 289 Gene3D G3DSA:1.10.760.10 32 254 1.4E-76 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Astex_0819 7a23f91dcc35078b491bb55aca5687d7 106 SUPERFAMILY SSF48295 17 101 4.18E-23 T 13-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 Astex_0819 7a23f91dcc35078b491bb55aca5687d7 106 Pfam PF01371 Trp repressor protein 18 99 4.9E-22 T 13-10-2018 IPR000831 Trp repressor GO:0003700|GO:0005622|GO:0006355 Astex_0819 7a23f91dcc35078b491bb55aca5687d7 106 Gene3D G3DSA:1.10.1270.10 7 106 8.8E-32 T 13-10-2018 IPR038116 TrpR-like superfamily Astex_0819 7a23f91dcc35078b491bb55aca5687d7 106 PIRSF PIRSF012508 4 106 1.1E-30 T 13-10-2018 IPR013368 TrpR homologue YerC/YecD Astex_0819 7a23f91dcc35078b491bb55aca5687d7 106 TIGRFAM TIGR02531 yecD_yerC: TrpR homolog YerC/YecD 18 101 2.2E-22 T 13-10-2018 IPR013368 TrpR homologue YerC/YecD Astex_2273 d616f419828ef7119503372452fe217c 1014 SUPERFAMILY SSF53756 509 864 2.76E-17 T 13-10-2018 Astex_2273 d616f419828ef7119503372452fe217c 1014 SUPERFAMILY SSF53448 239 482 1.01E-30 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_2273 d616f419828ef7119503372452fe217c 1014 Pfam PF00535 Glycosyl transferase family 2 239 348 7.7E-10 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 Astex_2273 d616f419828ef7119503372452fe217c 1014 Gene3D G3DSA:3.90.550.10 230 464 3.7E-29 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_2273 d616f419828ef7119503372452fe217c 1014 Gene3D G3DSA:3.40.50.2000 716 867 4.6E-9 T 13-10-2018 Astex_3002 a5e6b68b06d50213e3f2beb2e162a5d4 136 Pfam PF01850 PIN domain 6 116 7.9E-19 T 13-10-2018 IPR002716 PIN domain Astex_3002 a5e6b68b06d50213e3f2beb2e162a5d4 136 Gene3D G3DSA:3.40.50.1010 2 130 2.8E-11 T 13-10-2018 Astex_3002 a5e6b68b06d50213e3f2beb2e162a5d4 136 SUPERFAMILY SSF88723 6 132 1.88E-21 T 13-10-2018 IPR029060 PIN-like domain superfamily Astex_2345 6873cb1fb6c203904e336e63cd9e92f5 176 Gene3D G3DSA:2.40.160.20 24 176 1.1E-15 T 13-10-2018 Astex_2345 6873cb1fb6c203904e336e63cd9e92f5 176 Pfam PF13505 Outer membrane protein beta-barrel domain 12 173 3.8E-15 T 13-10-2018 IPR027385 Outer membrane protein beta-barrel Astex_2345 6873cb1fb6c203904e336e63cd9e92f5 176 SUPERFAMILY SSF56925 24 163 1.41E-15 T 13-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel Astex_2044 c09ff3bd023db4459ec56294399150d1 332 SUPERFAMILY SSF51735 6 325 5.43E-61 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_2044 c09ff3bd023db4459ec56294399150d1 332 Gene3D G3DSA:3.40.50.720 1 328 1.9E-66 T 13-10-2018 Astex_2044 c09ff3bd023db4459ec56294399150d1 332 Pfam PF01370 NAD dependent epimerase/dehydratase family 7 230 4.7E-32 T 13-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 Astex_2289 9b04c55eefc3c1dd4581e87ea5d11dca 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 37 57 5.1E-7 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Astex_2289 9b04c55eefc3c1dd4581e87ea5d11dca 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 210 234 5.1E-7 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Astex_2289 9b04c55eefc3c1dd4581e87ea5d11dca 266 Pfam PF00459 Inositol monophosphatase family 9 248 1.3E-51 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Astex_2289 9b04c55eefc3c1dd4581e87ea5d11dca 266 Gene3D G3DSA:3.40.190.80 153 261 2.1E-34 T 13-10-2018 Astex_2289 9b04c55eefc3c1dd4581e87ea5d11dca 266 Hamap MF_02095 3'(2'),5'-bisphosphate nucleotidase CysQ [cysQ]. 5 260 39.092 T 13-10-2018 IPR006240 3'(2'),5'-bisphosphate nucleotidase CysQ GO:0000287|GO:0006790|GO:0008441 KEGG: 00920+3.1.3.7 Astex_2289 9b04c55eefc3c1dd4581e87ea5d11dca 266 Gene3D G3DSA:3.30.540.10 7 147 1.1E-42 T 13-10-2018 Astex_2289 9b04c55eefc3c1dd4581e87ea5d11dca 266 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 213 227 - T 13-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 Astex_2289 9b04c55eefc3c1dd4581e87ea5d11dca 266 TIGRFAM TIGR01331 bisphos_cysQ: 3'(2'),5'-bisphosphate nucleotidase 11 258 1.6E-87 T 13-10-2018 IPR006240 3'(2'),5'-bisphosphate nucleotidase CysQ GO:0000287|GO:0006790|GO:0008441 KEGG: 00920+3.1.3.7 Astex_2289 9b04c55eefc3c1dd4581e87ea5d11dca 266 SUPERFAMILY SSF56655 11 245 2.09E-71 T 13-10-2018 Astex_1716 d4473dd16a76117f7011070c614f7da2 264 SUPERFAMILY SSF56655 7 261 1.44E-79 T 13-10-2018 Astex_1716 d4473dd16a76117f7011070c614f7da2 264 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 214 228 - T 13-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 Astex_1716 d4473dd16a76117f7011070c614f7da2 264 Pfam PF00459 Inositol monophosphatase family 7 260 1.1E-60 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Astex_1716 d4473dd16a76117f7011070c614f7da2 264 Gene3D G3DSA:3.40.190.80 144 262 4.6E-34 T 13-10-2018 Astex_1716 d4473dd16a76117f7011070c614f7da2 264 Gene3D G3DSA:3.30.540.10 2 143 3.9E-49 T 13-10-2018 Astex_1716 d4473dd16a76117f7011070c614f7da2 264 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 84 97 - T 13-10-2018 IPR020583 Inositol monophosphatase, metal-binding site Astex_1716 d4473dd16a76117f7011070c614f7da2 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 63 79 5.3E-53 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Astex_1716 d4473dd16a76117f7011070c614f7da2 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 133 156 5.3E-53 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Astex_1716 d4473dd16a76117f7011070c614f7da2 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 211 235 5.3E-53 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Astex_1716 d4473dd16a76117f7011070c614f7da2 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 84 100 5.3E-53 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Astex_1716 d4473dd16a76117f7011070c614f7da2 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 41 61 5.3E-53 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Astex_1716 d4473dd16a76117f7011070c614f7da2 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 180 201 5.3E-53 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Astex_1716 d4473dd16a76117f7011070c614f7da2 264 PRINTS PR01959 SuhB family inositol monophosphatase signature 201 213 5.6E-24 T 13-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 Astex_1716 d4473dd16a76117f7011070c614f7da2 264 PRINTS PR01959 SuhB family inositol monophosphatase signature 20 42 5.6E-24 T 13-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 Astex_1716 d4473dd16a76117f7011070c614f7da2 264 PRINTS PR01959 SuhB family inositol monophosphatase signature 107 126 5.6E-24 T 13-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 Astex_1716 d4473dd16a76117f7011070c614f7da2 264 PRINTS PR01959 SuhB family inositol monophosphatase signature 159 185 5.6E-24 T 13-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 Astex_2511 901f2ffb15748b967192ec85a3818d43 264 Gene3D G3DSA:3.40.1280.10 16 180 3.1E-54 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Astex_2511 901f2ffb15748b967192ec85a3818d43 264 SUPERFAMILY SSF75217 18 176 3.14E-35 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases Astex_2511 901f2ffb15748b967192ec85a3818d43 264 Pfam PF00588 SpoU rRNA Methylase family 19 169 9.6E-31 T 13-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 Astex_2511 901f2ffb15748b967192ec85a3818d43 264 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 20 250 1.3E-50 T 13-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 Astex_2511 901f2ffb15748b967192ec85a3818d43 264 Gene3D G3DSA:1.10.8.590 181 260 3.2E-12 T 13-10-2018 Astex_2511 901f2ffb15748b967192ec85a3818d43 264 PIRSF PIRSF004808 15 255 1.3E-77 T 13-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 Astex_2918 9514d2da3e113fc6a2d7171efb8f63a8 466 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 347 455 5.8E-38 T 13-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 Astex_2918 9514d2da3e113fc6a2d7171efb8f63a8 466 Gene3D G3DSA:3.50.50.60 152 275 2.1E-111 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_2918 9514d2da3e113fc6a2d7171efb8f63a8 466 SUPERFAMILY SSF51905 1 338 8.01E-64 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_2918 9514d2da3e113fc6a2d7171efb8f63a8 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 281 3.7E-35 T 13-10-2018 Astex_2918 9514d2da3e113fc6a2d7171efb8f63a8 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 178 196 3.7E-35 T 13-10-2018 Astex_2918 9514d2da3e113fc6a2d7171efb8f63a8 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 293 315 3.7E-35 T 13-10-2018 Astex_2918 9514d2da3e113fc6a2d7171efb8f63a8 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 3.7E-35 T 13-10-2018 Astex_2918 9514d2da3e113fc6a2d7171efb8f63a8 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 137 155 3.7E-35 T 13-10-2018 Astex_2918 9514d2da3e113fc6a2d7171efb8f63a8 466 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 37 47 - T 13-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 Astex_2918 9514d2da3e113fc6a2d7171efb8f63a8 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 266 280 9.1E-62 T 13-10-2018 Astex_2918 9514d2da3e113fc6a2d7171efb8f63a8 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 140 149 9.1E-62 T 13-10-2018 Astex_2918 9514d2da3e113fc6a2d7171efb8f63a8 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 178 203 9.1E-62 T 13-10-2018 Astex_2918 9514d2da3e113fc6a2d7171efb8f63a8 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 9.1E-62 T 13-10-2018 Astex_2918 9514d2da3e113fc6a2d7171efb8f63a8 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 408 423 9.1E-62 T 13-10-2018 Astex_2918 9514d2da3e113fc6a2d7171efb8f63a8 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 430 450 9.1E-62 T 13-10-2018 Astex_2918 9514d2da3e113fc6a2d7171efb8f63a8 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 36 51 9.1E-62 T 13-10-2018 Astex_2918 9514d2da3e113fc6a2d7171efb8f63a8 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 308 315 9.1E-62 T 13-10-2018 Astex_2918 9514d2da3e113fc6a2d7171efb8f63a8 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 343 364 9.1E-62 T 13-10-2018 Astex_2918 9514d2da3e113fc6a2d7171efb8f63a8 466 SUPERFAMILY SSF55424 347 464 3.26E-40 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 Astex_2918 9514d2da3e113fc6a2d7171efb8f63a8 466 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 328 9.7E-70 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Astex_2918 9514d2da3e113fc6a2d7171efb8f63a8 466 Gene3D G3DSA:3.50.50.60 3 333 2.1E-111 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_2918 9514d2da3e113fc6a2d7171efb8f63a8 466 Gene3D G3DSA:3.30.390.30 346 466 2.3E-43 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 Astex_2918 9514d2da3e113fc6a2d7171efb8f63a8 466 PIRSF PIRSF000350 1 460 4.0E-86 T 13-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 Astex_2918 9514d2da3e113fc6a2d7171efb8f63a8 466 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 2 465 1.5E-164 T 13-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 Astex_1427 b1b6c59a1ab5dbc914fd8f615e5d4270 327 Gene3D G3DSA:3.90.245.10 4 276 5.8E-41 T 13-10-2018 IPR036452 Ribonucleoside hydrolase-like Astex_1427 b1b6c59a1ab5dbc914fd8f615e5d4270 327 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 29 315 4.1E-33 T 13-10-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain Astex_1427 b1b6c59a1ab5dbc914fd8f615e5d4270 327 SUPERFAMILY SSF53590 27 320 3.53E-35 T 13-10-2018 IPR036452 Ribonucleoside hydrolase-like Astex_0641 25345765b6889b9e9849316027009c81 369 SMART SM00633 77 363 3.9E-39 T 13-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 Astex_0641 25345765b6889b9e9849316027009c81 369 Pfam PF00331 Glycosyl hydrolase family 10 35 362 1.7E-81 T 13-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 Astex_0641 25345765b6889b9e9849316027009c81 369 SUPERFAMILY SSF51445 32 364 1.3E-82 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_0641 25345765b6889b9e9849316027009c81 369 PRINTS PR00134 Glycosyl hydrolase family 10 signature 202 213 7.5E-11 T 13-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 Astex_0641 25345765b6889b9e9849316027009c81 369 PRINTS PR00134 Glycosyl hydrolase family 10 signature 108 120 7.5E-11 T 13-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 Astex_0641 25345765b6889b9e9849316027009c81 369 PRINTS PR00134 Glycosyl hydrolase family 10 signature 157 168 7.5E-11 T 13-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 Astex_0641 25345765b6889b9e9849316027009c81 369 PRINTS PR00134 Glycosyl hydrolase family 10 signature 233 245 7.5E-11 T 13-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 Astex_0641 25345765b6889b9e9849316027009c81 369 Gene3D G3DSA:3.20.20.80 26 366 6.9E-86 T 13-10-2018 Astex_3369 5c6c50bd8a2a02031ddb38791fd1f0f1 253 Gene3D G3DSA:3.40.50.720 3 253 4.2E-82 T 13-10-2018 Astex_3369 5c6c50bd8a2a02031ddb38791fd1f0f1 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Astex_3369 5c6c50bd8a2a02031ddb38791fd1f0f1 253 TIGRFAM TIGR01832 kduD: 2-deoxy-D-gluconate 3-dehydrogenase 7 253 6.6E-118 T 13-10-2018 IPR011286 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase GO:0008678|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.127|MetaCyc: PWY-6507|MetaCyc: PWY-7562 Astex_3369 5c6c50bd8a2a02031ddb38791fd1f0f1 253 SUPERFAMILY SSF51735 6 252 4.57E-81 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_3369 5c6c50bd8a2a02031ddb38791fd1f0f1 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 2.3E-42 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_3369 5c6c50bd8a2a02031ddb38791fd1f0f1 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 2.3E-42 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_3369 5c6c50bd8a2a02031ddb38791fd1f0f1 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 2.3E-42 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_3369 5c6c50bd8a2a02031ddb38791fd1f0f1 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 2.3E-42 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_3369 5c6c50bd8a2a02031ddb38791fd1f0f1 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 2.3E-42 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_3369 5c6c50bd8a2a02031ddb38791fd1f0f1 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 2.3E-42 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_3369 5c6c50bd8a2a02031ddb38791fd1f0f1 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 4.7E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_3369 5c6c50bd8a2a02031ddb38791fd1f0f1 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 4.7E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_3369 5c6c50bd8a2a02031ddb38791fd1f0f1 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 4.7E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_3369 5c6c50bd8a2a02031ddb38791fd1f0f1 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 12 212 0.0086 T 13-10-2018 Astex_3369 5c6c50bd8a2a02031ddb38791fd1f0f1 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 250 1.4E-60 T 13-10-2018 Astex_2963 c55fcfe277d05b7f765931a7b3988ecd 131 SUPERFAMILY SSF56214 1 127 3.4E-28 T 13-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 Astex_2963 c55fcfe277d05b7f765931a7b3988ecd 131 Gene3D G3DSA:3.90.470.20 1 128 3.6E-33 T 13-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 Astex_2963 c55fcfe277d05b7f765931a7b3988ecd 131 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 96 2.2E-20 T 13-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 Astex_2963 c55fcfe277d05b7f765931a7b3988ecd 131 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 1 128 2.0E-24 T 13-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 Astex_2963 c55fcfe277d05b7f765931a7b3988ecd 131 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 1 129 6.6E-28 T 13-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 Astex_2963 c55fcfe277d05b7f765931a7b3988ecd 131 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 127 3.0E-18 T 13-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 Astex_2963 c55fcfe277d05b7f765931a7b3988ecd 131 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 128 23.827 T 13-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 Astex_3434 1cbb7e2f5d95be62dc5bab8714fc39f6 494 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 281 310 2.9E-5 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_3434 1cbb7e2f5d95be62dc5bab8714fc39f6 494 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 380 409 2.9E-5 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_3434 1cbb7e2f5d95be62dc5bab8714fc39f6 494 SUPERFAMILY SSF55785 19 122 6.98E-25 T 13-10-2018 IPR035965 PAS domain superfamily Astex_3434 1cbb7e2f5d95be62dc5bab8714fc39f6 494 SMART SM00283 260 493 6.2E-23 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_3434 1cbb7e2f5d95be62dc5bab8714fc39f6 494 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 143 250 8.8E-12 T 13-10-2018 IPR000014 PAS domain Astex_3434 1cbb7e2f5d95be62dc5bab8714fc39f6 494 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 17 126 8.5E-15 T 13-10-2018 IPR000014 PAS domain Astex_3434 1cbb7e2f5d95be62dc5bab8714fc39f6 494 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 333 487 3.0E-26 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_3434 1cbb7e2f5d95be62dc5bab8714fc39f6 494 Gene3D G3DSA:3.30.450.20 136 295 9.6E-24 T 13-10-2018 Astex_3434 1cbb7e2f5d95be62dc5bab8714fc39f6 494 SUPERFAMILY SSF55785 143 247 4.36E-24 T 13-10-2018 IPR035965 PAS domain superfamily Astex_3434 1cbb7e2f5d95be62dc5bab8714fc39f6 494 Gene3D G3DSA:3.30.450.20 7 135 3.8E-24 T 13-10-2018 Astex_3434 1cbb7e2f5d95be62dc5bab8714fc39f6 494 SUPERFAMILY SSF58104 158 492 1.66E-49 T 13-10-2018 Astex_3434 1cbb7e2f5d95be62dc5bab8714fc39f6 494 SMART SM00091 8 78 0.23 T 13-10-2018 IPR000014 PAS domain Astex_3434 1cbb7e2f5d95be62dc5bab8714fc39f6 494 SMART SM00091 130 200 2.2 T 13-10-2018 IPR000014 PAS domain Astex_3434 1cbb7e2f5d95be62dc5bab8714fc39f6 494 Pfam PF08447 PAS fold 155 240 6.9E-14 T 13-10-2018 IPR013655 PAS fold-3 GO:0005515 Astex_3434 1cbb7e2f5d95be62dc5bab8714fc39f6 494 Pfam PF08447 PAS fold 32 118 9.1E-16 T 13-10-2018 IPR013655 PAS fold-3 GO:0005515 Astex_3434 1cbb7e2f5d95be62dc5bab8714fc39f6 494 Gene3D G3DSA:1.10.287.950 296 494 1.5E-37 T 13-10-2018 Astex_3434 1cbb7e2f5d95be62dc5bab8714fc39f6 494 SMART SM00086 83 125 7.6E-6 T 13-10-2018 IPR001610 PAC motif Astex_3434 1cbb7e2f5d95be62dc5bab8714fc39f6 494 SMART SM00086 205 247 0.0041 T 13-10-2018 IPR001610 PAC motif Astex_1026 bd127c3eed49f2479713fff57152175f 195 Pfam PF13628 Domain of unknown function (DUF4142) 58 191 4.0E-40 T 13-10-2018 IPR025419 Domain of unknown function DUF4142 Astex_1026 bd127c3eed49f2479713fff57152175f 195 Gene3D G3DSA:1.20.1260.10 70 195 2.3E-7 T 13-10-2018 IPR012347 Ferritin-like Astex_2151 c6f720ac806fe4a4fbf4ac1c2143303c 230 TIGRFAM TIGR03584 PseF: pseudaminic acid cytidylyltransferase 4 223 1.4E-95 T 13-10-2018 IPR020039 Pseudaminic acid cytidylyltransferase KEGG: 00520+2.7.7.81|MetaCyc: PWY-6143 Astex_2151 c6f720ac806fe4a4fbf4ac1c2143303c 230 Gene3D G3DSA:3.90.550.10 2 224 5.0E-61 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_2151 c6f720ac806fe4a4fbf4ac1c2143303c 230 Pfam PF02348 Cytidylyltransferase 4 202 2.2E-32 T 13-10-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 Astex_2151 c6f720ac806fe4a4fbf4ac1c2143303c 230 SUPERFAMILY SSF53448 1 225 3.99E-56 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_1986 4f071e0347c4de16ceb4fcc8fbd48a4a 337 Gene3D G3DSA:3.40.50.2300 168 297 1.0E-60 T 13-10-2018 Astex_1986 4f071e0347c4de16ceb4fcc8fbd48a4a 337 SUPERFAMILY SSF53822 78 336 1.16E-59 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Astex_1986 4f071e0347c4de16ceb4fcc8fbd48a4a 337 SMART SM00354 4 74 2.5E-7 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Astex_1986 4f071e0347c4de16ceb4fcc8fbd48a4a 337 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 48 9.9E-14 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Astex_1986 4f071e0347c4de16ceb4fcc8fbd48a4a 337 Gene3D G3DSA:3.40.50.2300 60 312 1.0E-60 T 13-10-2018 Astex_1986 4f071e0347c4de16ceb4fcc8fbd48a4a 337 Gene3D G3DSA:1.10.260.40 2 48 2.2E-14 T 13-10-2018 Astex_1986 4f071e0347c4de16ceb4fcc8fbd48a4a 337 SUPERFAMILY SSF47413 4 54 3.56E-12 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Astex_1986 4f071e0347c4de16ceb4fcc8fbd48a4a 337 Pfam PF13377 Periplasmic binding protein-like domain 177 335 1.8E-33 T 13-10-2018 Astex_1986 4f071e0347c4de16ceb4fcc8fbd48a4a 337 ProSitePatterns PS00356 LacI-type HTH domain signature. 7 25 - T 13-10-2018 Astex_1701 ee0af2e8ebd2c132224e00f9923f6f63 135 SUPERFAMILY SSF54637 9 117 2.75E-25 T 13-10-2018 IPR029069 HotDog domain superfamily Astex_1701 ee0af2e8ebd2c132224e00f9923f6f63 135 Pfam PF13279 Thioesterase-like superfamily 16 117 1.0E-13 T 13-10-2018 Astex_1701 ee0af2e8ebd2c132224e00f9923f6f63 135 PIRSF PIRSF003230 3 127 1.0E-20 T 13-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 Astex_1701 ee0af2e8ebd2c132224e00f9923f6f63 135 Gene3D G3DSA:3.10.129.10 5 131 3.3E-26 T 13-10-2018 Astex_2855 3a7b54b08e97c47cb58b01dadcbfe971 261 Gene3D G3DSA:1.20.1180.10 193 259 2.5E-15 T 13-10-2018 IPR037157 UDP-N-acetylglucosamine O-acyltransferase, C-terminal domain superfamily KEGG: 00540+2.3.1.129 Astex_2855 3a7b54b08e97c47cb58b01dadcbfe971 261 TIGRFAM TIGR01852 lipid_A_lpxA: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase 3 257 6.8E-109 T 13-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 Astex_2855 3a7b54b08e97c47cb58b01dadcbfe971 261 Hamap MF_00387 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase [lpxA]. 1 258 42.433 T 13-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 Astex_2855 3a7b54b08e97c47cb58b01dadcbfe971 261 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 175 257 9.7E-23 T 13-10-2018 IPR029098 UDP N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00540+2.3.1.129 Astex_2855 3a7b54b08e97c47cb58b01dadcbfe971 261 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 15 43 - T 13-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 Astex_2855 3a7b54b08e97c47cb58b01dadcbfe971 261 PIRSF PIRSF000456 1 261 1.2E-106 T 13-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 Astex_2855 3a7b54b08e97c47cb58b01dadcbfe971 261 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 104 138 3.6E-7 T 13-10-2018 IPR001451 Hexapeptide repeat Astex_2855 3a7b54b08e97c47cb58b01dadcbfe971 261 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 31 65 3.7E-6 T 13-10-2018 IPR001451 Hexapeptide repeat Astex_2855 3a7b54b08e97c47cb58b01dadcbfe971 261 Gene3D G3DSA:2.160.10.10 1 190 1.8E-51 T 13-10-2018 Astex_2855 3a7b54b08e97c47cb58b01dadcbfe971 261 SUPERFAMILY SSF51161 2 254 6.32E-74 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily Astex_1625 4b75ad2cad0e68d720ab5611e7c3ef8d 561 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 476 505 4.6E-20 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_1625 4b75ad2cad0e68d720ab5611e7c3ef8d 561 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 322 351 4.6E-20 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_1625 4b75ad2cad0e68d720ab5611e7c3ef8d 561 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 428 457 4.6E-20 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_1625 4b75ad2cad0e68d720ab5611e7c3ef8d 561 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 399 426 4.6E-20 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_1625 4b75ad2cad0e68d720ab5611e7c3ef8d 561 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 363 526 1.1E-26 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_1625 4b75ad2cad0e68d720ab5611e7c3ef8d 561 Gene3D G3DSA:1.20.1480.50 173 269 8.1E-15 T 13-10-2018 Astex_1625 4b75ad2cad0e68d720ab5611e7c3ef8d 561 Gene3D G3DSA:1.10.287.950 270 561 7.8E-49 T 13-10-2018 Astex_1625 4b75ad2cad0e68d720ab5611e7c3ef8d 561 SUPERFAMILY SSF58104 240 554 1.7E-58 T 13-10-2018 Astex_1625 4b75ad2cad0e68d720ab5611e7c3ef8d 561 SMART SM00283 301 555 1.6E-34 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_0034 b747eab874387b5941d19433bfbbabcb 959 SUPERFAMILY SSF55021 758 831 1.64E-10 T 13-10-2018 Astex_0034 b747eab874387b5941d19433bfbbabcb 959 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 78 139 3.3E-5 T 13-10-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 Astex_0034 b747eab874387b5941d19433bfbbabcb 959 Gene3D G3DSA:3.30.460.100 5 152 2.0E-7 T 13-10-2018 Astex_0034 b747eab874387b5941d19433bfbbabcb 959 SMART SM00471 513 660 5.9E-6 T 13-10-2018 IPR003607 HD/PDEase domain Astex_0034 b747eab874387b5941d19433bfbbabcb 959 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 50 952 240.163 T 13-10-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 Astex_0034 b747eab874387b5941d19433bfbbabcb 959 Pfam PF08335 GlnD PII-uridylyltransferase 220 371 1.1E-31 T 13-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 Astex_0034 b747eab874387b5941d19433bfbbabcb 959 Gene3D G3DSA:1.10.3090.10 413 711 3.2E-12 T 13-10-2018 Astex_0034 b747eab874387b5941d19433bfbbabcb 959 PIRSF PIRSF006288 37 948 8.2E-279 T 13-10-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 Astex_0034 b747eab874387b5941d19433bfbbabcb 959 SUPERFAMILY SSF81301 22 208 1.44E-27 T 13-10-2018 Astex_0034 b747eab874387b5941d19433bfbbabcb 959 SUPERFAMILY SSF55021 866 936 1.76E-9 T 13-10-2018 Astex_0034 b747eab874387b5941d19433bfbbabcb 959 SUPERFAMILY SSF81891 424 660 2.16E-21 T 13-10-2018 Astex_0034 b747eab874387b5941d19433bfbbabcb 959 Pfam PF01966 HD domain 517 642 9.7E-9 T 13-10-2018 IPR006674 HD domain Astex_0034 b747eab874387b5941d19433bfbbabcb 959 Gene3D G3DSA:3.30.70.260 864 940 8.5E-6 T 13-10-2018 Astex_0034 b747eab874387b5941d19433bfbbabcb 959 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 62 939 2.1E-272 T 13-10-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 Astex_0034 b747eab874387b5941d19433bfbbabcb 959 SUPERFAMILY SSF81593 240 365 2.67E-5 T 13-10-2018 Astex_0497 703700a2cc384fd35313fd261f15de80 248 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 155 175 - T 13-10-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 Astex_0497 703700a2cc384fd35313fd261f15de80 248 Pfam PF01012 Electron transfer flavoprotein domain 29 206 2.6E-46 T 13-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 Astex_0497 703700a2cc384fd35313fd261f15de80 248 SMART SM00893 23 211 7.7E-68 T 13-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 Astex_0497 703700a2cc384fd35313fd261f15de80 248 PIRSF PIRSF000090 1 248 7.2E-85 T 13-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 Astex_0497 703700a2cc384fd35313fd261f15de80 248 SUPERFAMILY SSF52402 1 241 1.81E-84 T 13-10-2018 Astex_0497 703700a2cc384fd35313fd261f15de80 248 Gene3D G3DSA:3.40.50.620 1 248 1.5E-87 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Astex_0883 1a59817f885ba80e71c5c75c47d8a822 603 Pfam PF13177 DNA polymerase III, delta subunit 58 220 6.1E-32 T 13-10-2018 Astex_0883 1a59817f885ba80e71c5c75c47d8a822 603 Gene3D G3DSA:1.10.8.60 46 283 1.1E-97 T 13-10-2018 Astex_0883 1a59817f885ba80e71c5c75c47d8a822 603 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 41 401 6.8E-122 T 13-10-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 Astex_0883 1a59817f885ba80e71c5c75c47d8a822 603 SMART SM00382 75 221 7.8E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_0883 1a59817f885ba80e71c5c75c47d8a822 603 Gene3D G3DSA:1.20.272.10 286 403 4.3E-13 T 13-10-2018 Astex_0883 1a59817f885ba80e71c5c75c47d8a822 603 SUPERFAMILY SSF48019 287 411 4.93E-24 T 13-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 Astex_0883 1a59817f885ba80e71c5c75c47d8a822 603 SUPERFAMILY SSF52540 70 265 2.31E-52 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0883 1a59817f885ba80e71c5c75c47d8a822 603 Gene3D G3DSA:3.40.50.300 51 219 1.1E-97 T 13-10-2018 Astex_0883 1a59817f885ba80e71c5c75c47d8a822 603 Pfam PF12362 DNA polymerase III gamma and tau subunits C terminal 461 572 3.9E-32 T 13-10-2018 IPR022107 DNA polymerase III, subunit gamma/ tau, C-terminal Astex_0883 1a59817f885ba80e71c5c75c47d8a822 603 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 276 416 3.9E-42 T 13-10-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 Astex_0700 563f5bb9d742aa541ea64201032f7251 187 Gene3D G3DSA:3.40.30.10 1 186 9.6E-59 T 13-10-2018 Astex_0700 563f5bb9d742aa541ea64201032f7251 187 PIRSF PIRSF000239 1 187 9.0E-52 T 13-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 Astex_0700 563f5bb9d742aa541ea64201032f7251 187 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 156 181 8.0E-7 T 13-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 Astex_0700 563f5bb9d742aa541ea64201032f7251 187 SUPERFAMILY SSF52833 1 186 6.73E-55 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Astex_0700 563f5bb9d742aa541ea64201032f7251 187 Pfam PF00578 AhpC/TSA family 7 133 1.4E-30 T 13-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 Astex_0700 563f5bb9d742aa541ea64201032f7251 187 TIGRFAM TIGR03137 AhpC: peroxiredoxin 1 187 1.2E-99 T 13-10-2018 IPR017559 Alkyl hydroperoxide reductase subunit C GO:0006979|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 Astex_1670 4fe0aeeb5aa2d389b8d8fb3d98dc71fe 302 SUPERFAMILY SSF48452 51 173 4.03E-9 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_1670 4fe0aeeb5aa2d389b8d8fb3d98dc71fe 302 Hamap MF_00922 Outer membrane protein assembly factor BamD [bamD]. 17 251 33.877 T 13-10-2018 IPR017689 Outer membrane protein assembly factor BamD Astex_1670 4fe0aeeb5aa2d389b8d8fb3d98dc71fe 302 TIGRFAM TIGR03302 OM_YfiO: outer membrane assembly lipoprotein YfiO 19 257 1.5E-79 T 13-10-2018 IPR017689 Outer membrane protein assembly factor BamD Astex_1670 4fe0aeeb5aa2d389b8d8fb3d98dc71fe 302 Pfam PF13525 Outer membrane lipoprotein 49 243 2.5E-52 T 13-10-2018 IPR039565 Outer membrane lipoprotein BamD-like Astex_1670 4fe0aeeb5aa2d389b8d8fb3d98dc71fe 302 Gene3D G3DSA:1.25.40.10 49 262 9.9E-53 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_3317 53e676f29d4a5268b33a889e7a0ce274 518 SMART SM00813 321 510 1.7E-72 T 13-10-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 Astex_3317 53e676f29d4a5268b33a889e7a0ce274 518 SUPERFAMILY SSF51445 38 401 1.26E-85 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_3317 53e676f29d4a5268b33a889e7a0ce274 518 Gene3D G3DSA:2.60.40.1180 35 513 3.5E-176 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta Astex_3317 53e676f29d4a5268b33a889e7a0ce274 518 SUPERFAMILY SSF51011 389 516 3.96E-24 T 13-10-2018 Astex_3317 53e676f29d4a5268b33a889e7a0ce274 518 Gene3D G3DSA:3.20.20.80 39 403 3.5E-176 T 13-10-2018 Astex_3317 53e676f29d4a5268b33a889e7a0ce274 518 Pfam PF06964 Alpha-L-arabinofuranosidase C-terminal domain 321 510 4.5E-39 T 13-10-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 Astex_0892 7ca13817fa3e89bee1d7ed355051d78e 309 SUPERFAMILY SSF50486 203 308 1.27E-27 T 13-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 Astex_0892 7ca13817fa3e89bee1d7ed355051d78e 309 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 1 300 6.5E-81 T 13-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 Astex_0892 7ca13817fa3e89bee1d7ed355051d78e 309 Gene3D G3DSA:3.40.50.12230 1 308 1.5E-95 T 13-10-2018 Astex_0892 7ca13817fa3e89bee1d7ed355051d78e 309 SUPERFAMILY SSF53328 1 204 5.49E-57 T 13-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Astex_0892 7ca13817fa3e89bee1d7ed355051d78e 309 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 303 34.372 T 13-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 Astex_0892 7ca13817fa3e89bee1d7ed355051d78e 309 Pfam PF00551 Formyl transferase 1 179 2.5E-38 T 13-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Astex_0892 7ca13817fa3e89bee1d7ed355051d78e 309 Pfam PF02911 Formyl transferase, C-terminal domain 202 300 7.2E-24 T 13-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Astex_2535 235504f096aaee3bb64f8e881243848e 451 Gene3D G3DSA:3.20.20.140 72 389 3.2E-151 T 13-10-2018 Astex_2535 235504f096aaee3bb64f8e881243848e 451 TIGRFAM TIGR02967 guan_deamin: guanine deaminase 20 442 5.6E-125 T 13-10-2018 IPR014311 Guanine deaminase GO:0006147|GO:0008270|GO:0008892 KEGG: 00230+3.5.4.3|MetaCyc: PWY-5497|MetaCyc: PWY-6606|MetaCyc: PWY-6608|MetaCyc: PWY-7442|Reactome: R-HSA-74259 Astex_2535 235504f096aaee3bb64f8e881243848e 451 Pfam PF01979 Amidohydrolase family 69 443 8.2E-52 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 Astex_2535 235504f096aaee3bb64f8e881243848e 451 Gene3D G3DSA:2.30.40.10 7 442 3.2E-151 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Astex_2535 235504f096aaee3bb64f8e881243848e 451 SUPERFAMILY SSF51556 71 390 1.01E-87 T 13-10-2018 IPR032466 Metal-dependent hydrolase Astex_2535 235504f096aaee3bb64f8e881243848e 451 SUPERFAMILY SSF51338 363 448 8.09E-15 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Astex_2544 c2d087a6b4e62f83b96ff227f96a38a9 124 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 50 105 16.707 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_2544 c2d087a6b4e62f83b96ff227f96a38a9 124 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 51 106 5.8E-20 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_2544 c2d087a6b4e62f83b96ff227f96a38a9 124 ProSitePatterns PS01181 Ribosomal protein S21 signature. 61 73 - T 13-10-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_2544 c2d087a6b4e62f83b96ff227f96a38a9 124 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 63 90 1.0E-9 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_2544 c2d087a6b4e62f83b96ff227f96a38a9 124 Gene3D G3DSA:1.20.5.1150 64 102 7.4E-8 T 13-10-2018 IPR038380 Ribosomal protein S21 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_2544 c2d087a6b4e62f83b96ff227f96a38a9 124 Pfam PF01165 Ribosomal protein S21 52 105 9.0E-18 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_2765 c7228b6a52c228204cff89d68cd63b0d 406 Gene3D G3DSA:3.40.640.10 36 296 2.9E-173 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Astex_2765 c7228b6a52c228204cff89d68cd63b0d 406 SUPERFAMILY SSF53383 3 401 3.23E-126 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Astex_2765 c7228b6a52c228204cff89d68cd63b0d 406 Pfam PF00266 Aminotransferase class-V 25 394 1.8E-146 T 13-10-2018 IPR000192 Aminotransferase class V domain Astex_2765 c7228b6a52c228204cff89d68cd63b0d 406 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 217 236 - T 13-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site Astex_2765 c7228b6a52c228204cff89d68cd63b0d 406 Gene3D G3DSA:3.90.1150.10 8 397 2.9E-173 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Astex_2765 c7228b6a52c228204cff89d68cd63b0d 406 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 7 405 1.3E-176 T 13-10-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 Astex_2765 c7228b6a52c228204cff89d68cd63b0d 406 PIRSF PIRSF005572 22 403 6.7E-49 T 13-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 Astex_0701 3852b3b5d3d4c47cc2515cc77cee238c 1035 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 48 1035 2.7E-190 T 13-10-2018 IPR010104 Bacterial TonB-dependent receptor Astex_0701 3852b3b5d3d4c47cc2515cc77cee238c 1035 Gene3D G3DSA:2.170.130.10 41 189 7.8E-17 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_0701 3852b3b5d3d4c47cc2515cc77cee238c 1035 Pfam PF07715 TonB-dependent Receptor Plug Domain 67 182 1.7E-16 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_0701 3852b3b5d3d4c47cc2515cc77cee238c 1035 SUPERFAMILY SSF56935 49 1035 3.15E-78 T 13-10-2018 Astex_0701 3852b3b5d3d4c47cc2515cc77cee238c 1035 Pfam PF00593 TonB dependent receptor 462 1034 5.3E-34 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_3511 410beeea89dcfa275f8c1ee1e2584d7f 441 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 348 439 1.1E-25 T 13-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Astex_3511 410beeea89dcfa275f8c1ee1e2584d7f 441 Gene3D G3DSA:3.40.50.20 21 113 5.5E-34 T 13-10-2018 Astex_3511 410beeea89dcfa275f8c1ee1e2584d7f 441 SUPERFAMILY SSF51246 346 441 2.51E-28 T 13-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 Astex_3511 410beeea89dcfa275f8c1ee1e2584d7f 441 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 21 120 1.0E-33 T 13-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Astex_3511 410beeea89dcfa275f8c1ee1e2584d7f 441 Gene3D G3DSA:3.30.470.20 208 344 9.0E-53 T 13-10-2018 Astex_3511 410beeea89dcfa275f8c1ee1e2584d7f 441 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 21 441 41.257 T 13-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Astex_3511 410beeea89dcfa275f8c1ee1e2584d7f 441 SMART SM01210 347 441 1.8E-43 T 13-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Astex_3511 410beeea89dcfa275f8c1ee1e2584d7f 441 SMART SM01209 121 312 3.4E-116 T 13-10-2018 Astex_3511 410beeea89dcfa275f8c1ee1e2584d7f 441 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 306 313 - T 13-10-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Astex_3511 410beeea89dcfa275f8c1ee1e2584d7f 441 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 21 441 5.7E-151 T 13-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Astex_3511 410beeea89dcfa275f8c1ee1e2584d7f 441 SUPERFAMILY SSF56059 122 338 1.36E-55 T 13-10-2018 Astex_3511 410beeea89dcfa275f8c1ee1e2584d7f 441 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 121 312 3.0E-71 T 13-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Astex_3511 410beeea89dcfa275f8c1ee1e2584d7f 441 SUPERFAMILY SSF52440 20 121 5.75E-34 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily Astex_3511 410beeea89dcfa275f8c1ee1e2584d7f 441 Gene3D G3DSA:3.90.600.10 347 441 1.1E-28 T 13-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Astex_3511 410beeea89dcfa275f8c1ee1e2584d7f 441 Gene3D G3DSA:3.30.1490.20 139 207 2.1E-20 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 Astex_0417 b69103480726fb52335dd19c1f841e29 717 SMART SM00990 425 537 1.3E-17 T 13-10-2018 IPR014883 VRR-NUC domain GO:0016788 Reactome: R-HSA-6783310 Astex_0417 b69103480726fb52335dd19c1f841e29 717 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 544 701 2.2E-35 T 13-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Astex_0417 b69103480726fb52335dd19c1f841e29 717 SUPERFAMILY SSF53098 540 708 8.49E-55 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily Astex_0417 b69103480726fb52335dd19c1f841e29 717 Pfam PF00929 Exonuclease 547 700 2.6E-35 T 13-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III Astex_0417 b69103480726fb52335dd19c1f841e29 717 Gene3D G3DSA:3.40.1350.10 466 544 3.8E-9 T 13-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 Astex_0417 b69103480726fb52335dd19c1f841e29 717 Pfam PF08774 VRR-NUC domain 467 536 1.0E-10 T 13-10-2018 IPR014883 VRR-NUC domain GO:0016788 Reactome: R-HSA-6783310 Astex_0417 b69103480726fb52335dd19c1f841e29 717 Gene3D G3DSA:3.30.420.10 545 709 4.7E-49 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Astex_0417 b69103480726fb52335dd19c1f841e29 717 SMART SM00479 544 709 4.9E-44 T 13-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III Astex_2848 b9e5938dd2973bc253bf0db294fdae1f 276 Pfam PF01148 Cytidylyltransferase family 19 262 3.1E-53 T 13-10-2018 Astex_2848 b9e5938dd2973bc253bf0db294fdae1f 276 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 228 254 - T 13-10-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 Astex_0154 8dd950688787187bc3bae6076787b7b5 207 SUPERFAMILY SSF54427 15 201 1.26E-24 T 13-10-2018 IPR032710 NTF2-like domain superfamily Astex_0154 8dd950688787187bc3bae6076787b7b5 207 SMART SM00978 62 204 3.4E-20 T 13-10-2018 IPR007379 Tim44-like domain Astex_0154 8dd950688787187bc3bae6076787b7b5 207 Pfam PF04280 Tim44-like domain 66 203 5.2E-24 T 13-10-2018 IPR007379 Tim44-like domain Astex_0154 8dd950688787187bc3bae6076787b7b5 207 Gene3D G3DSA:3.10.450.240 63 206 2.1E-15 T 13-10-2018 Astex_3515 e93f0e490d8f0b7cd0868961726cfa41 236 ProDom PD032436 LIPOPROTEIN UNCHARACTERIZED PROBABLE CJ0457C SIMILAR TRANSFERASE BACTERIA PRECURSOR SIGNAL CC0304 55 141 1.0E-18 T 13-10-2018 IPR007172 Domain of unknown function DUF374 Astex_3515 e93f0e490d8f0b7cd0868961726cfa41 236 Pfam PF04028 Domain of unknown function (DUF374) 69 142 3.2E-21 T 13-10-2018 IPR007172 Domain of unknown function DUF374 Astex_3692 b62bc2addf98f49932d91bf8761ada46 181 Gene3D G3DSA:1.10.1740.10 5 106 1.2E-5 T 13-10-2018 Astex_3692 b62bc2addf98f49932d91bf8761ada46 181 Pfam PF04542 Sigma-70 region 2 21 87 1.7E-4 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 Astex_3692 b62bc2addf98f49932d91bf8761ada46 181 Pfam PF08281 Sigma-70, region 4 118 169 5.8E-11 T 13-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Astex_3692 b62bc2addf98f49932d91bf8761ada46 181 SUPERFAMILY SSF88946 18 94 3.88E-9 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 Astex_3692 b62bc2addf98f49932d91bf8761ada46 181 SUPERFAMILY SSF88659 88 175 9.72E-17 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Astex_3692 b62bc2addf98f49932d91bf8761ada46 181 Gene3D G3DSA:1.10.10.10 116 177 4.0E-11 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_3692 b62bc2addf98f49932d91bf8761ada46 181 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 173 3.0E-22 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 Astex_3086 756e9fd86066e3efe21e07a52e7b1b34 205 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 47 61 - T 13-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Astex_3086 756e9fd86066e3efe21e07a52e7b1b34 205 SUPERFAMILY SSF55120 4 201 2.56E-56 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 Astex_3086 756e9fd86066e3efe21e07a52e7b1b34 205 Pfam PF00849 RNA pseudouridylate synthase 10 154 1.2E-27 T 13-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 Astex_3086 756e9fd86066e3efe21e07a52e7b1b34 205 Gene3D G3DSA:3.30.2350.10 1 204 1.9E-64 T 13-10-2018 Astex_2607 93038f306420ea731935d4e68c2d523b 402 Gene3D G3DSA:1.50.10.20 26 372 5.9E-106 T 13-10-2018 Astex_2607 93038f306420ea731935d4e68c2d523b 402 SUPERFAMILY SSF81853 47 369 9.55E-62 T 13-10-2018 Astex_2607 93038f306420ea731935d4e68c2d523b 402 Pfam PF09492 Pectic acid lyase 64 362 3.0E-76 T 13-10-2018 IPR012669 Pectic acid lyase Astex_2607 93038f306420ea731935d4e68c2d523b 402 TIGRFAM TIGR02474 pec_lyase: pectate lyase 64 361 1.9E-73 T 13-10-2018 IPR012669 Pectic acid lyase Astex_3545 f8b8efdca591d9b84038661368c03578 644 Gene3D G3DSA:3.30.565.10 483 641 1.3E-36 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_3545 f8b8efdca591d9b84038661368c03578 644 SUPERFAMILY SSF47384 397 479 1.08E-17 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Astex_3545 f8b8efdca591d9b84038661368c03578 644 SMART SM00086 350 392 9.9E-4 T 13-10-2018 IPR001610 PAC motif Astex_3545 f8b8efdca591d9b84038661368c03578 644 SUPERFAMILY SSF55874 468 636 7.6E-40 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_3545 f8b8efdca591d9b84038661368c03578 644 Pfam PF00989 PAS fold 279 388 1.7E-14 T 13-10-2018 IPR013767 PAS fold GO:0006355 Astex_3545 f8b8efdca591d9b84038661368c03578 644 Gene3D G3DSA:1.10.287.130 403 480 3.6E-21 T 13-10-2018 Astex_3545 f8b8efdca591d9b84038661368c03578 644 SMART SM00091 277 344 1.0E-4 T 13-10-2018 IPR000014 PAS domain Astex_3545 f8b8efdca591d9b84038661368c03578 644 Gene3D G3DSA:1.20.1440.210 57 182 1.9E-15 T 13-10-2018 Astex_3545 f8b8efdca591d9b84038661368c03578 644 Gene3D G3DSA:1.20.1480.50 183 272 6.1E-8 T 13-10-2018 Astex_3545 f8b8efdca591d9b84038661368c03578 644 Gene3D G3DSA:3.30.450.20 273 402 3.4E-30 T 13-10-2018 Astex_3545 f8b8efdca591d9b84038661368c03578 644 SMART SM00387 525 636 3.5E-31 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_3545 f8b8efdca591d9b84038661368c03578 644 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 526 634 8.2E-24 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_3545 f8b8efdca591d9b84038661368c03578 644 SUPERFAMILY SSF55785 267 387 1.2E-28 T 13-10-2018 IPR035965 PAS domain superfamily Astex_3545 f8b8efdca591d9b84038661368c03578 644 SMART SM00388 412 479 9.5E-19 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_3545 f8b8efdca591d9b84038661368c03578 644 Pfam PF00512 His Kinase A (phospho-acceptor) domain 412 479 1.4E-15 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_3545 f8b8efdca591d9b84038661368c03578 644 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 273 399 2.4E-25 T 13-10-2018 IPR000014 PAS domain Astex_3545 f8b8efdca591d9b84038661368c03578 644 PRINTS PR00344 Bacterial sensor protein C-terminal signature 562 576 7.3E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_3545 f8b8efdca591d9b84038661368c03578 644 PRINTS PR00344 Bacterial sensor protein C-terminal signature 620 633 7.3E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_3545 f8b8efdca591d9b84038661368c03578 644 PRINTS PR00344 Bacterial sensor protein C-terminal signature 597 615 7.3E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_3545 f8b8efdca591d9b84038661368c03578 644 PRINTS PR00344 Bacterial sensor protein C-terminal signature 580 590 7.3E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_3545 f8b8efdca591d9b84038661368c03578 644 Pfam PF05227 CHASE3 domain 49 186 4.7E-23 T 13-10-2018 IPR007891 CHASE3 Astex_1445 a91339da3276041f30a07e795a71cfa8 209 SUPERFAMILY SSF46689 8 90 6.48E-22 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Astex_1445 a91339da3276041f30a07e795a71cfa8 209 Pfam PF16859 Bacterial transcriptional repressor C-terminal 117 176 1.1E-7 T 13-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Astex_1445 a91339da3276041f30a07e795a71cfa8 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 3.7E-11 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Astex_1445 a91339da3276041f30a07e795a71cfa8 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 3.7E-11 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Astex_1445 a91339da3276041f30a07e795a71cfa8 209 Gene3D G3DSA:1.10.357.10 10 209 8.3E-42 T 13-10-2018 Astex_1445 a91339da3276041f30a07e795a71cfa8 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 67 1.4E-18 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Astex_1445 a91339da3276041f30a07e795a71cfa8 209 SUPERFAMILY SSF48498 113 208 8.31E-14 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily Astex_2287 5093d0997c17776158dd8ea0556470fa 640 SUPERFAMILY SSF50465 328 430 2.11E-34 T 13-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal Astex_2287 5093d0997c17776158dd8ea0556470fa 640 Gene3D G3DSA:2.40.30.10 238 325 4.3E-25 T 13-10-2018 Astex_2287 5093d0997c17776158dd8ea0556470fa 640 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 458 630 37.934 T 13-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 Astex_2287 5093d0997c17776158dd8ea0556470fa 640 Gene3D G3DSA:3.40.50.300 6 236 5.9E-69 T 13-10-2018 Astex_2287 5093d0997c17776158dd8ea0556470fa 640 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 444 624 5.4E-77 T 13-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 Astex_2287 5093d0997c17776158dd8ea0556470fa 640 SUPERFAMILY SSF50447 239 325 5.41E-24 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Astex_2287 5093d0997c17776158dd8ea0556470fa 640 Gene3D G3DSA:3.40.50.300 436 635 7.1E-76 T 13-10-2018 Astex_2287 5093d0997c17776158dd8ea0556470fa 640 PRINTS PR00315 GTP-binding elongation factor signature 107 117 2.9E-12 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Astex_2287 5093d0997c17776158dd8ea0556470fa 640 PRINTS PR00315 GTP-binding elongation factor signature 87 95 2.9E-12 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Astex_2287 5093d0997c17776158dd8ea0556470fa 640 PRINTS PR00315 GTP-binding elongation factor signature 123 134 2.9E-12 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Astex_2287 5093d0997c17776158dd8ea0556470fa 640 PRINTS PR00315 GTP-binding elongation factor signature 160 169 2.9E-12 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Astex_2287 5093d0997c17776158dd8ea0556470fa 640 PRINTS PR00315 GTP-binding elongation factor signature 26 39 2.9E-12 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Astex_2287 5093d0997c17776158dd8ea0556470fa 640 Gene3D G3DSA:2.40.30.10 327 430 3.4E-36 T 13-10-2018 Astex_2287 5093d0997c17776158dd8ea0556470fa 640 SUPERFAMILY SSF52540 18 233 4.43E-58 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2287 5093d0997c17776158dd8ea0556470fa 640 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 80 95 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site Astex_2287 5093d0997c17776158dd8ea0556470fa 640 Pfam PF00009 Elongation factor Tu GTP binding domain 24 209 2.3E-39 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Astex_2287 5093d0997c17776158dd8ea0556470fa 640 SUPERFAMILY SSF52540 456 628 9.63E-35 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2287 5093d0997c17776158dd8ea0556470fa 640 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 25 430 3.9E-198 T 13-10-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 Astex_2287 5093d0997c17776158dd8ea0556470fa 640 Hamap MF_00062 Sulfate adenylyltransferase subunit 1 [cysN]. 16 459 53.912 T 13-10-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 Astex_2287 5093d0997c17776158dd8ea0556470fa 640 Pfam PF01583 Adenylylsulphate kinase 460 611 6.1E-71 T 13-10-2018 Astex_2043 f87ee5ca4f2892523a5c89bc90ed7a99 281 SUPERFAMILY SSF56281 32 274 3.8E-29 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Astex_2043 f87ee5ca4f2892523a5c89bc90ed7a99 281 Pfam PF00753 Metallo-beta-lactamase superfamily 38 207 3.6E-17 T 13-10-2018 IPR001279 Metallo-beta-lactamase Astex_2043 f87ee5ca4f2892523a5c89bc90ed7a99 281 SMART SM00849 33 256 9.1E-8 T 13-10-2018 IPR001279 Metallo-beta-lactamase Astex_2043 f87ee5ca4f2892523a5c89bc90ed7a99 281 Gene3D G3DSA:3.60.15.10 5 278 9.5E-48 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Astex_0054 02ecc22a6609266bba5448fee700fe76 198 PRINTS PR00773 GrpE protein signature 67 82 3.6E-24 T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 Astex_0054 02ecc22a6609266bba5448fee700fe76 198 PRINTS PR00773 GrpE protein signature 152 171 3.6E-24 T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 Astex_0054 02ecc22a6609266bba5448fee700fe76 198 PRINTS PR00773 GrpE protein signature 39 55 3.6E-24 T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 Astex_0054 02ecc22a6609266bba5448fee700fe76 198 PRINTS PR00773 GrpE protein signature 125 140 3.6E-24 T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 Astex_0054 02ecc22a6609266bba5448fee700fe76 198 SUPERFAMILY SSF58014 16 116 7.72E-25 T 13-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 Astex_0054 02ecc22a6609266bba5448fee700fe76 198 Pfam PF01025 GrpE 9 172 1.1E-48 T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 Astex_0054 02ecc22a6609266bba5448fee700fe76 198 Hamap MF_01151 Protein GrpE [grpE]. 2 173 18.797 T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 Astex_0054 02ecc22a6609266bba5448fee700fe76 198 ProSitePatterns PS01071 grpE protein signature. 128 170 - T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 Astex_0054 02ecc22a6609266bba5448fee700fe76 198 Gene3D G3DSA:2.30.22.10 116 172 5.1E-20 T 13-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 Astex_0054 02ecc22a6609266bba5448fee700fe76 198 SUPERFAMILY SSF51064 122 172 1.7E-15 T 13-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 Astex_0054 02ecc22a6609266bba5448fee700fe76 198 Gene3D G3DSA:3.90.20.20 9 115 1.4E-25 T 13-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 Astex_3042 df66b4dc3b776503f17d9faab64e176c 309 Gene3D G3DSA:3.90.870.10 1 199 2.9E-63 T 13-10-2018 Astex_3042 df66b4dc3b776503f17d9faab64e176c 309 Pfam PF01300 Telomere recombination 10 185 2.1E-47 T 13-10-2018 IPR006070 YrdC-like domain GO:0003725 Astex_3042 df66b4dc3b776503f17d9faab64e176c 309 PIRSF PIRSF004930 1 308 5.2E-93 T 13-10-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 Astex_3042 df66b4dc3b776503f17d9faab64e176c 309 Pfam PF03481 Putative GTP-binding controlling metal-binding 187 306 5.6E-19 T 13-10-2018 IPR005145 Putative GTP-binding controlling metal-binding domain Astex_3042 df66b4dc3b776503f17d9faab64e176c 309 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 3 195 7.4E-47 T 13-10-2018 IPR006070 YrdC-like domain GO:0003725 Astex_3042 df66b4dc3b776503f17d9faab64e176c 309 SUPERFAMILY SSF55821 4 197 6.1E-54 T 13-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily Astex_3042 df66b4dc3b776503f17d9faab64e176c 309 Gene3D G3DSA:3.40.50.11030 200 308 6.0E-14 T 13-10-2018 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily Astex_1888 bfc60096c598526016b47ee920453249 410 Pfam PF00480 ROK family 105 366 7.9E-19 T 13-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 Astex_1888 bfc60096c598526016b47ee920453249 410 Pfam PF13412 Winged helix-turn-helix DNA-binding 33 78 4.4E-5 T 13-10-2018 Astex_1888 bfc60096c598526016b47ee920453249 410 SUPERFAMILY SSF46785 33 98 4.02E-13 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_1888 bfc60096c598526016b47ee920453249 410 Gene3D G3DSA:3.30.420.40 232 368 3.4E-16 T 13-10-2018 Astex_1888 bfc60096c598526016b47ee920453249 410 Gene3D G3DSA:3.30.420.40 99 231 1.2E-20 T 13-10-2018 Astex_1888 bfc60096c598526016b47ee920453249 410 Gene3D G3DSA:1.10.10.10 23 98 3.2E-16 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1888 bfc60096c598526016b47ee920453249 410 SUPERFAMILY SSF53067 104 395 5.36E-32 T 13-10-2018 Astex_1438 c06960ef534bdcd3c85faa3a7afef824 209 Gene3D G3DSA:1.20.120.1760 4 209 1.4E-12 T 13-10-2018 Astex_1438 c06960ef534bdcd3c85faa3a7afef824 209 Pfam PF01066 CDP-alcohol phosphatidyltransferase 9 88 3.0E-16 T 13-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 Astex_1438 c06960ef534bdcd3c85faa3a7afef824 209 PIRSF PIRSF000847 4 209 4.9E-41 T 13-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 Astex_1438 c06960ef534bdcd3c85faa3a7afef824 209 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 66 88 - T 13-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 Astex_1438 c06960ef534bdcd3c85faa3a7afef824 209 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 9 208 1.5E-37 T 13-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 Astex_1698 ac8241b03d75cbb086e9ff5ad736e8be 378 SUPERFAMILY SSF51338 4 361 5.46E-12 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Astex_1698 ac8241b03d75cbb086e9ff5ad736e8be 378 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 36 366 5.6E-91 T 13-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 Astex_1698 ac8241b03d75cbb086e9ff5ad736e8be 378 SUPERFAMILY SSF51556 48 342 2.72E-93 T 13-10-2018 IPR032466 Metal-dependent hydrolase Astex_1698 ac8241b03d75cbb086e9ff5ad736e8be 378 Pfam PF01979 Amidohydrolase family 44 369 3.9E-24 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 Astex_1698 ac8241b03d75cbb086e9ff5ad736e8be 378 PIRSF PIRSF038994 3 373 1.2E-108 T 13-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 Astex_1698 ac8241b03d75cbb086e9ff5ad736e8be 378 Gene3D G3DSA:3.20.20.140 49 336 3.5E-117 T 13-10-2018 Astex_1698 ac8241b03d75cbb086e9ff5ad736e8be 378 Gene3D G3DSA:2.30.40.10 7 368 3.5E-117 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Astex_0861 7e9b6f653a7e00f7125ee52f60074a27 153 Gene3D G3DSA:1.20.1260.10 3 153 3.9E-51 T 13-10-2018 IPR012347 Ferritin-like Astex_0861 7e9b6f653a7e00f7125ee52f60074a27 153 PIRSF PIRSF005900 1 153 4.0E-43 T 13-10-2018 IPR002177 DNA-binding protein Dps Astex_0861 7e9b6f653a7e00f7125ee52f60074a27 153 Pfam PF00210 Ferritin-like domain 16 152 3.1E-32 T 13-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 Astex_0861 7e9b6f653a7e00f7125ee52f60074a27 153 SUPERFAMILY SSF47240 11 153 1.84E-43 T 13-10-2018 IPR009078 Ferritin-like superfamily Astex_0861 7e9b6f653a7e00f7125ee52f60074a27 153 ProSitePatterns PS00819 Dps protein family signature 2. 60 74 - T 13-10-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 Astex_0861 7e9b6f653a7e00f7125ee52f60074a27 153 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 34 50 9.6E-12 T 13-10-2018 IPR002177 DNA-binding protein Dps Astex_0861 7e9b6f653a7e00f7125ee52f60074a27 153 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 58 74 9.6E-12 T 13-10-2018 IPR002177 DNA-binding protein Dps Astex_0861 7e9b6f653a7e00f7125ee52f60074a27 153 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 129 147 9.6E-12 T 13-10-2018 IPR002177 DNA-binding protein Dps Astex_1039 16f1d1da4f55b40fe8f1a01064135a9a 365 Pfam PF03929 PepSY-associated TM region 8 358 1.8E-53 T 13-10-2018 IPR005625 PepSY-associated TM protein Astex_0006 5b12270129f91168d76fa2727c4df492 687 SUPERFAMILY SSF51445 304 530 1.6E-25 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_0006 5b12270129f91168d76fa2727c4df492 687 Pfam PF10566 Glycoside hydrolase 97 304 585 5.8E-103 T 13-10-2018 IPR019563 Glycosyl-hydrolase 97, catalytic domain Astex_0006 5b12270129f91168d76fa2727c4df492 687 Pfam PF14508 Glycosyl-hydrolase 97 N-terminal 32 297 5.0E-49 T 13-10-2018 IPR029486 Glycosyl-hydrolase 97, N-terminal domain Astex_0006 5b12270129f91168d76fa2727c4df492 687 Gene3D G3DSA:3.20.20.70 300 586 3.6E-101 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_0006 5b12270129f91168d76fa2727c4df492 687 Gene3D G3DSA:2.60.40.1180 588 678 1.7E-23 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta Astex_0006 5b12270129f91168d76fa2727c4df492 687 Pfam PF14509 Glycosyl-hydrolase 97 C-terminal, oligomerisation 588 677 3.0E-23 T 13-10-2018 IPR029483 Glycosyl-hydrolase 97, C-terminal oligomerisation domain Astex_0006 5b12270129f91168d76fa2727c4df492 687 Gene3D G3DSA:2.70.98.10 18 298 2.5E-50 T 13-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 Astex_3124 157b8b39887f673f1bc18ba1791b3985 281 SUPERFAMILY SSF55060 161 277 1.29E-25 T 13-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily Astex_3124 157b8b39887f673f1bc18ba1791b3985 281 Gene3D G3DSA:3.30.230.10 1 160 2.3E-39 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Astex_3124 157b8b39887f673f1bc18ba1791b3985 281 Gene3D G3DSA:3.30.70.890 161 280 1.1E-26 T 13-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily Astex_3124 157b8b39887f673f1bc18ba1791b3985 281 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 3 280 25.917 T 13-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 Astex_3124 157b8b39887f673f1bc18ba1791b3985 281 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 5 262 5.9E-43 T 13-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 Astex_3124 157b8b39887f673f1bc18ba1791b3985 281 Pfam PF08544 GHMP kinases C terminal 213 271 6.5E-8 T 13-10-2018 IPR013750 GHMP kinase, C-terminal domain Astex_3124 157b8b39887f673f1bc18ba1791b3985 281 SUPERFAMILY SSF54211 3 158 4.33E-28 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Astex_3124 157b8b39887f673f1bc18ba1791b3985 281 PIRSF PIRSF010376 1 281 8.8E-69 T 13-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 Astex_1955 46db07a1c620abf8b0f8cd07243ecf1a 890 Gene3D G3DSA:1.20.1440.90 255 378 7.5E-7 T 13-10-2018 Astex_1955 46db07a1c620abf8b0f8cd07243ecf1a 890 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 541 553 - T 13-10-2018 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Astex_1955 46db07a1c620abf8b0f8cd07243ecf1a 890 Pfam PF00311 Phosphoenolpyruvate carboxylase 119 890 8.6E-236 T 13-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Astex_1955 46db07a1c620abf8b0f8cd07243ecf1a 890 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 121 132 - T 13-10-2018 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Astex_1955 46db07a1c620abf8b0f8cd07243ecf1a 890 SUPERFAMILY SSF51621 11 890 5.65E-237 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 Astex_1955 46db07a1c620abf8b0f8cd07243ecf1a 890 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 1 890 16.192 T 13-10-2018 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Astex_1955 46db07a1c620abf8b0f8cd07243ecf1a 890 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 120 133 2.5E-48 T 13-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Astex_1955 46db07a1c620abf8b0f8cd07243ecf1a 890 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 376 396 2.5E-48 T 13-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Astex_1955 46db07a1c620abf8b0f8cd07243ecf1a 890 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 226 241 2.5E-48 T 13-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Astex_1955 46db07a1c620abf8b0f8cd07243ecf1a 890 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 581 610 2.5E-48 T 13-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Astex_1955 46db07a1c620abf8b0f8cd07243ecf1a 890 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 539 559 2.5E-48 T 13-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Astex_1955 46db07a1c620abf8b0f8cd07243ecf1a 890 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 722 748 2.5E-48 T 13-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 Astex_1370 518016931321b5c9665f4b2056970809 295 ProSitePatterns PS01125 ROK family signature. 134 159 - T 13-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 Astex_1370 518016931321b5c9665f4b2056970809 295 Gene3D G3DSA:3.30.420.40 2 108 8.2E-23 T 13-10-2018 Astex_1370 518016931321b5c9665f4b2056970809 295 SUPERFAMILY SSF53067 1 293 9.02E-37 T 13-10-2018 Astex_1370 518016931321b5c9665f4b2056970809 295 Gene3D G3DSA:3.30.420.40 109 295 4.3E-54 T 13-10-2018 Astex_1370 518016931321b5c9665f4b2056970809 295 Pfam PF00480 ROK family 5 292 3.4E-52 T 13-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 Astex_2469 be6139ebd8c6070519e38628ed670fbc 317 Pfam PF12833 Helix-turn-helix domain 232 311 1.0E-21 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Astex_2469 be6139ebd8c6070519e38628ed670fbc 317 Gene3D G3DSA:1.10.10.60 206 316 2.6E-26 T 13-10-2018 Astex_2469 be6139ebd8c6070519e38628ed670fbc 317 SMART SM00342 225 310 1.4E-24 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Astex_2469 be6139ebd8c6070519e38628ed670fbc 317 SUPERFAMILY SSF46689 260 312 7.17E-11 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Astex_2469 be6139ebd8c6070519e38628ed670fbc 317 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 279 294 6.5E-7 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 Astex_2469 be6139ebd8c6070519e38628ed670fbc 317 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 294 310 6.5E-7 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 Astex_2469 be6139ebd8c6070519e38628ed670fbc 317 Pfam PF14525 AraC-binding-like domain 57 176 4.2E-8 T 13-10-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like Astex_3307 cdd09cadc9e6005792785ad8ce91d647 502 Pfam PF04820 Tryptophan halogenase 7 464 4.0E-180 T 13-10-2018 IPR006905 Flavin-dependent halogenase Astex_3307 cdd09cadc9e6005792785ad8ce91d647 502 Gene3D G3DSA:3.50.50.60 4 496 9.4E-189 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_3307 cdd09cadc9e6005792785ad8ce91d647 502 PIRSF PIRSF011396 2 501 5.4E-191 T 13-10-2018 IPR033856 Flavin-dependent tryptophan halogenase Astex_3307 cdd09cadc9e6005792785ad8ce91d647 502 SUPERFAMILY SSF51905 7 425 3.89E-33 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_3840 05ef94f3bc5ea331d8924f1717cd6448 414 Gene3D G3DSA:1.20.1600.10 23 414 1.2E-52 T 13-10-2018 Astex_3840 05ef94f3bc5ea331d8924f1717cd6448 414 Pfam PF02321 Outer membrane efflux protein 233 407 4.8E-19 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Astex_3840 05ef94f3bc5ea331d8924f1717cd6448 414 Pfam PF02321 Outer membrane efflux protein 29 214 5.7E-13 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Astex_3840 05ef94f3bc5ea331d8924f1717cd6448 414 SUPERFAMILY SSF56954 2 410 2.88E-59 T 13-10-2018 Astex_0094 ac394585a1e545dea12cc2d90615bee4 131 SUPERFAMILY SSF47413 19 77 6.7E-11 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Astex_0094 ac394585a1e545dea12cc2d90615bee4 131 SMART SM00530 27 81 7.5E-7 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Astex_0094 ac394585a1e545dea12cc2d90615bee4 131 Gene3D G3DSA:1.10.260.40 16 87 4.1E-12 T 13-10-2018 Astex_0094 ac394585a1e545dea12cc2d90615bee4 131 Pfam PF13560 Helix-turn-helix domain 24 77 9.8E-9 T 13-10-2018 Astex_0443 5b94a0b947e930424c1f64c2c58e3936 229 Pfam PF03379 CcmB protein 13 225 2.4E-52 T 13-10-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 Astex_0443 5b94a0b947e930424c1f64c2c58e3936 229 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 85 108 2.4E-44 T 13-10-2018 Astex_0443 5b94a0b947e930424c1f64c2c58e3936 229 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 165 184 2.4E-44 T 13-10-2018 Astex_0443 5b94a0b947e930424c1f64c2c58e3936 229 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 202 225 2.4E-44 T 13-10-2018 Astex_0443 5b94a0b947e930424c1f64c2c58e3936 229 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 62 79 2.4E-44 T 13-10-2018 Astex_0443 5b94a0b947e930424c1f64c2c58e3936 229 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 36 57 2.4E-44 T 13-10-2018 Astex_0443 5b94a0b947e930424c1f64c2c58e3936 229 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 110 128 2.4E-44 T 13-10-2018 Astex_0443 5b94a0b947e930424c1f64c2c58e3936 229 PIRSF PIRSF002764 6 229 3.0E-62 T 13-10-2018 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria Astex_0443 5b94a0b947e930424c1f64c2c58e3936 229 TIGRFAM TIGR01190 ccmB: heme exporter protein CcmB 15 225 3.4E-52 T 13-10-2018 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria Astex_3347 b4345b5313676932df96deadf53b88bb 339 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 50 9.9E-14 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Astex_3347 b4345b5313676932df96deadf53b88bb 339 ProSitePatterns PS00356 LacI-type HTH domain signature. 6 24 - T 13-10-2018 Astex_3347 b4345b5313676932df96deadf53b88bb 339 Pfam PF13377 Periplasmic binding protein-like domain 176 332 1.9E-35 T 13-10-2018 Astex_3347 b4345b5313676932df96deadf53b88bb 339 Gene3D G3DSA:3.40.50.2300 165 294 5.4E-66 T 13-10-2018 Astex_3347 b4345b5313676932df96deadf53b88bb 339 SUPERFAMILY SSF53822 63 336 5.3E-66 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Astex_3347 b4345b5313676932df96deadf53b88bb 339 SMART SM00354 3 74 1.7E-20 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Astex_3347 b4345b5313676932df96deadf53b88bb 339 Gene3D G3DSA:1.10.260.40 1 57 5.9E-19 T 13-10-2018 Astex_3347 b4345b5313676932df96deadf53b88bb 339 SUPERFAMILY SSF47413 3 61 4.92E-15 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Astex_3347 b4345b5313676932df96deadf53b88bb 339 Gene3D G3DSA:3.40.50.2300 58 311 5.4E-66 T 13-10-2018 Astex_3130 172a3ab772b24e269f911a8a571ab8e7 419 SUPERFAMILY SSF53335 56 418 1.06E-45 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Astex_3130 172a3ab772b24e269f911a8a571ab8e7 419 Gene3D G3DSA:3.40.50.150 68 414 9.0E-70 T 13-10-2018 Astex_3130 172a3ab772b24e269f911a8a571ab8e7 419 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 207 416 3.8E-10 T 13-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 Astex_3130 172a3ab772b24e269f911a8a571ab8e7 419 Gene3D G3DSA:3.40.1350.30 112 255 9.0E-70 T 13-10-2018 Astex_3130 172a3ab772b24e269f911a8a571ab8e7 419 Gene3D G3DSA:2.40.50.140 1 67 5.7E-12 T 13-10-2018 Astex_3130 172a3ab772b24e269f911a8a571ab8e7 419 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 351 381 - T 13-10-2018 IPR030390 RNA methyltransferase TrmA, active site Astex_2152 48c2ffae9299535df12c0bee19a15d09 530 Pfam PF08502 LeuA allosteric (dimerisation) domain 380 519 1.3E-22 T 13-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Astex_2152 48c2ffae9299535df12c0bee19a15d09 530 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 12 28 - T 13-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Astex_2152 48c2ffae9299535df12c0bee19a15d09 530 SMART SM00917 375 522 1.6E-30 T 13-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Astex_2152 48c2ffae9299535df12c0bee19a15d09 530 Gene3D G3DSA:3.20.20.70 4 326 5.7E-108 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_2152 48c2ffae9299535df12c0bee19a15d09 530 SUPERFAMILY SSF51569 2 293 4.94E-81 T 13-10-2018 Astex_2152 48c2ffae9299535df12c0bee19a15d09 530 Pfam PF00682 HMGL-like 5 271 1.1E-47 T 13-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 Astex_2152 48c2ffae9299535df12c0bee19a15d09 530 SUPERFAMILY SSF110921 412 519 2.22E-21 T 13-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Astex_2152 48c2ffae9299535df12c0bee19a15d09 530 Gene3D G3DSA:3.30.160.270 403 521 1.1E-6 T 13-10-2018 Astex_2152 48c2ffae9299535df12c0bee19a15d09 530 TIGRFAM TIGR00977 citramal_synth: citramalate synthase 5 525 1.3E-197 T 13-10-2018 IPR005675 Citramalate synthase GO:0019752|GO:0046912 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101 Astex_0559 008004e73074d33a7a668b7f1a07de41 493 Gene3D G3DSA:3.40.710.10 155 473 2.5E-68 T 13-10-2018 Astex_0559 008004e73074d33a7a668b7f1a07de41 493 SUPERFAMILY SSF56601 160 470 6.57E-69 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like Astex_0559 008004e73074d33a7a668b7f1a07de41 493 Pfam PF00144 Beta-lactamase 184 457 9.9E-31 T 13-10-2018 IPR001466 Beta-lactamase-related Astex_0452 d2755c070e355847c1c24e56b6acd8b9 495 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 108 494 9.7E-154 T 13-10-2018 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 Astex_0452 d2755c070e355847c1c24e56b6acd8b9 495 Gene3D G3DSA:3.90.1210.30 3 85 2.0E-27 T 13-10-2018 Astex_0452 d2755c070e355847c1c24e56b6acd8b9 495 Pfam PF08666 SAF domain 11 81 2.5E-11 T 13-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 Astex_0452 d2755c070e355847c1c24e56b6acd8b9 495 SMART SM00858 11 82 2.7E-13 T 13-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 Astex_1935 800a1b2cf1c9574d8951eda53c3c696f 247 Gene3D G3DSA:3.40.190.10 105 206 2.1E-77 T 13-10-2018 Astex_1935 800a1b2cf1c9574d8951eda53c3c696f 247 PIRSF PIRSF004846 1 247 1.7E-51 T 13-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 Astex_1935 800a1b2cf1c9574d8951eda53c3c696f 247 SUPERFAMILY SSF53850 24 245 1.85E-60 T 13-10-2018 Astex_1935 800a1b2cf1c9574d8951eda53c3c696f 247 Gene3D G3DSA:3.40.190.10 30 244 2.1E-77 T 13-10-2018 Astex_1935 800a1b2cf1c9574d8951eda53c3c696f 247 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 31 243 9.2E-73 T 13-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 Astex_1935 800a1b2cf1c9574d8951eda53c3c696f 247 Pfam PF13531 Bacterial extracellular solute-binding protein 26 245 1.8E-49 T 13-10-2018 Astex_0361 e5023732ea827a8b5d6fbbf15b2a5159 443 SUPERFAMILY SSF82171 137 443 1.11E-20 T 13-10-2018 Astex_0361 e5023732ea827a8b5d6fbbf15b2a5159 443 Gene3D G3DSA:2.130.10.10 30 443 1.4E-102 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 Astex_0361 e5023732ea827a8b5d6fbbf15b2a5159 443 Pfam PF14583 Oligogalacturonate lyase 217 441 2.4E-17 T 13-10-2018 IPR027946 Oligogalacturonate lyase domain GO:0045490|GO:0047487 KEGG: 00040+4.2.2.6 Astex_0361 e5023732ea827a8b5d6fbbf15b2a5159 443 SUPERFAMILY SSF69304 38 170 3.01E-8 T 13-10-2018 Astex_1432 6f3f6b0d638d252aea6bc8e00ec3119b 1009 SUPERFAMILY SSF48452 534 895 5.32E-5 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_1432 6f3f6b0d638d252aea6bc8e00ec3119b 1009 Gene3D G3DSA:1.25.40.10 525 714 1.0E-8 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_1316 63c3007ccc6252c46c97a73de61e1c20 150 Pfam PF00072 Response regulator receiver domain 25 138 6.7E-28 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1316 63c3007ccc6252c46c97a73de61e1c20 150 Gene3D G3DSA:3.40.50.12740 22 149 1.0E-44 T 13-10-2018 Astex_1316 63c3007ccc6252c46c97a73de61e1c20 150 SMART SM00448 23 139 1.3E-39 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1316 63c3007ccc6252c46c97a73de61e1c20 150 SUPERFAMILY SSF52172 22 142 3.27E-40 T 13-10-2018 IPR011006 CheY-like superfamily Astex_0451 4604502e3dfa8ef61f36804d8e89184d 362 Pfam PF00356 Bacterial regulatory proteins, lacI family 25 70 7.9E-16 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Astex_0451 4604502e3dfa8ef61f36804d8e89184d 362 Gene3D G3DSA:1.10.260.40 21 76 3.7E-19 T 13-10-2018 Astex_0451 4604502e3dfa8ef61f36804d8e89184d 362 Gene3D G3DSA:3.40.50.2300 77 334 2.0E-69 T 13-10-2018 Astex_0451 4604502e3dfa8ef61f36804d8e89184d 362 SUPERFAMILY SSF53822 84 356 3.3E-66 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Astex_0451 4604502e3dfa8ef61f36804d8e89184d 362 Gene3D G3DSA:3.40.50.2300 189 318 2.0E-69 T 13-10-2018 Astex_0451 4604502e3dfa8ef61f36804d8e89184d 362 ProSitePatterns PS00356 LacI-type HTH domain signature. 26 44 - T 13-10-2018 Astex_0451 4604502e3dfa8ef61f36804d8e89184d 362 SUPERFAMILY SSF47413 22 81 6.19E-15 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Astex_0451 4604502e3dfa8ef61f36804d8e89184d 362 SMART SM00354 23 93 9.4E-23 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Astex_0451 4604502e3dfa8ef61f36804d8e89184d 362 Pfam PF13377 Periplasmic binding protein-like domain 197 353 1.9E-38 T 13-10-2018 Astex_3175 1f0efaca597ad93756cd35ae1d7a3b21 139 Gene3D G3DSA:3.30.1330.40 16 139 7.8E-32 T 13-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 Astex_3175 1f0efaca597ad93756cd35ae1d7a3b21 139 Pfam PF01042 Endoribonuclease L-PSP 22 134 2.8E-22 T 13-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 Astex_3175 1f0efaca597ad93756cd35ae1d7a3b21 139 SUPERFAMILY SSF55298 16 136 1.57E-30 T 13-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 Astex_2599 09bbbf4f61f23c8513131c4db04ea8e1 833 PIRSF PIRSF037149 5 833 6.9E-299 T 13-10-2018 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 Astex_2599 09bbbf4f61f23c8513131c4db04ea8e1 833 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 647 786 1.6E-25 T 13-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Astex_2599 09bbbf4f61f23c8513131c4db04ea8e1 833 Gene3D G3DSA:3.90.480.10 565 652 4.9E-6 T 13-10-2018 Astex_2599 09bbbf4f61f23c8513131c4db04ea8e1 833 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 13 807 1.6E-264 T 13-10-2018 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 Astex_2599 09bbbf4f61f23c8513131c4db04ea8e1 833 Pfam PF04324 BFD-like [2Fe-2S] binding domain 435 482 2.6E-9 T 13-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain Astex_2599 09bbbf4f61f23c8513131c4db04ea8e1 833 Pfam PF04324 BFD-like [2Fe-2S] binding domain 498 547 2.7E-11 T 13-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain Astex_2599 09bbbf4f61f23c8513131c4db04ea8e1 833 SUPERFAMILY SSF51905 10 203 2.31E-41 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_2599 09bbbf4f61f23c8513131c4db04ea8e1 833 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 573 637 5.3E-14 T 13-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Astex_2599 09bbbf4f61f23c8513131c4db04ea8e1 833 Gene3D G3DSA:3.30.413.10 653 780 1.7E-28 T 13-10-2018 Astex_2599 09bbbf4f61f23c8513131c4db04ea8e1 833 PRINTS PR00397 Sirohaem Fe-binding site signature 650 668 3.1E-6 T 13-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Astex_2599 09bbbf4f61f23c8513131c4db04ea8e1 833 PRINTS PR00397 Sirohaem Fe-binding site signature 693 711 3.1E-6 T 13-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Astex_2599 09bbbf4f61f23c8513131c4db04ea8e1 833 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 13 32 1.3E-21 T 13-10-2018 Astex_2599 09bbbf4f61f23c8513131c4db04ea8e1 833 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 114 132 1.3E-21 T 13-10-2018 Astex_2599 09bbbf4f61f23c8513131c4db04ea8e1 833 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 269 291 1.3E-21 T 13-10-2018 Astex_2599 09bbbf4f61f23c8513131c4db04ea8e1 833 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 244 260 1.3E-21 T 13-10-2018 Astex_2599 09bbbf4f61f23c8513131c4db04ea8e1 833 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 159 177 1.3E-21 T 13-10-2018 Astex_2599 09bbbf4f61f23c8513131c4db04ea8e1 833 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 12 292 4.0E-52 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Astex_2599 09bbbf4f61f23c8513131c4db04ea8e1 833 Gene3D G3DSA:3.50.50.60 127 251 2.1E-86 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_2599 09bbbf4f61f23c8513131c4db04ea8e1 833 Gene3D G3DSA:3.50.50.60 13 300 2.1E-86 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_2599 09bbbf4f61f23c8513131c4db04ea8e1 833 SUPERFAMILY SSF51905 160 317 2.87E-26 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_2599 09bbbf4f61f23c8513131c4db04ea8e1 833 SUPERFAMILY SSF56014 647 815 4.19E-51 T 13-10-2018 Astex_2599 09bbbf4f61f23c8513131c4db04ea8e1 833 Gene3D G3DSA:3.30.390.30 330 408 5.2E-7 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 Astex_2599 09bbbf4f61f23c8513131c4db04ea8e1 833 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 245 259 1.4E-9 T 13-10-2018 Astex_2599 09bbbf4f61f23c8513131c4db04ea8e1 833 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 284 291 1.4E-9 T 13-10-2018 Astex_2599 09bbbf4f61f23c8513131c4db04ea8e1 833 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 159 184 1.4E-9 T 13-10-2018 Astex_2599 09bbbf4f61f23c8513131c4db04ea8e1 833 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 12 34 1.4E-9 T 13-10-2018 Astex_2599 09bbbf4f61f23c8513131c4db04ea8e1 833 SUPERFAMILY SSF55124 533 655 5.89E-27 T 13-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Astex_2599 09bbbf4f61f23c8513131c4db04ea8e1 833 Gene3D G3DSA:1.10.10.1100 434 488 9.5E-10 T 13-10-2018 Astex_2599 09bbbf4f61f23c8513131c4db04ea8e1 833 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 693 709 - T 13-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Astex_0050 e65b3022727a6f96376e49caa33c0342 250 ProSitePatterns PS01277 Ribonuclease PH signature. 128 140 - T 13-10-2018 IPR018336 Ribonuclease PH, conserved site Astex_0050 e65b3022727a6f96376e49caa33c0342 250 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 14 247 5.9E-110 T 13-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 Astex_0050 e65b3022727a6f96376e49caa33c0342 250 SUPERFAMILY SSF54211 12 193 5.06E-45 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Astex_0050 e65b3022727a6f96376e49caa33c0342 250 Gene3D G3DSA:3.30.230.70 22 249 9.2E-61 T 13-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 Astex_0050 e65b3022727a6f96376e49caa33c0342 250 Pfam PF01138 3' exoribonuclease family, domain 1 22 151 3.3E-23 T 13-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 Astex_0050 e65b3022727a6f96376e49caa33c0342 250 SUPERFAMILY SSF55666 165 249 3.27E-23 T 13-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 Astex_0050 e65b3022727a6f96376e49caa33c0342 250 Pfam PF03725 3' exoribonuclease family, domain 2 170 235 2.7E-10 T 13-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 Astex_0050 e65b3022727a6f96376e49caa33c0342 250 Hamap MF_00564 Ribonuclease PH [rph]. 23 249 42.779 T 13-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 Astex_0912 97b4ca91e3e6aefae283d46ce06fd619 739 SUPERFAMILY SSF141868 479 719 5.89E-84 T 13-10-2018 IPR035919 EAL domain superfamily Astex_0912 97b4ca91e3e6aefae283d46ce06fd619 739 SMART SM00052 473 713 1.2E-105 T 13-10-2018 IPR001633 EAL domain Astex_0912 97b4ca91e3e6aefae283d46ce06fd619 739 Pfam PF00990 Diguanylate cyclase, GGDEF domain 303 458 2.1E-44 T 13-10-2018 IPR000160 GGDEF domain Astex_0912 97b4ca91e3e6aefae283d46ce06fd619 739 Pfam PF05228 CHASE4 domain 58 212 2.8E-8 T 13-10-2018 IPR007892 CHASE4 Astex_0912 97b4ca91e3e6aefae283d46ce06fd619 739 SMART SM00267 292 463 3.7E-60 T 13-10-2018 IPR000160 GGDEF domain Astex_0912 97b4ca91e3e6aefae283d46ce06fd619 739 SUPERFAMILY SSF55073 308 464 4.16E-45 T 13-10-2018 IPR029787 Nucleotide cyclase Astex_0912 97b4ca91e3e6aefae283d46ce06fd619 739 Pfam PF00563 EAL domain 481 708 7.4E-70 T 13-10-2018 IPR001633 EAL domain Astex_0912 97b4ca91e3e6aefae283d46ce06fd619 739 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 300 461 2.5E-41 T 13-10-2018 IPR000160 GGDEF domain Astex_0912 97b4ca91e3e6aefae283d46ce06fd619 739 Gene3D G3DSA:3.30.70.270 297 475 9.4E-54 T 13-10-2018 Astex_0912 97b4ca91e3e6aefae283d46ce06fd619 739 Gene3D G3DSA:3.20.20.450 476 733 3.1E-92 T 13-10-2018 IPR035919 EAL domain superfamily Astex_1990 d3ef8c965308a1fba4eb8a278254f3d5 60 Pfam PF07043 Protein of unknown function (DUF1328) 6 43 1.0E-11 T 13-10-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 Astex_1990 d3ef8c965308a1fba4eb8a278254f3d5 60 PIRSF PIRSF036466 1 55 4.7E-16 T 13-10-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 Astex_1990 d3ef8c965308a1fba4eb8a278254f3d5 60 Hamap MF_01361 UPF0391 membrane protein YtjA [ytjA]. 1 51 15.764 T 13-10-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 Astex_3536 f1334cd121b31eac437f257f8e34bf9a 1052 Gene3D G3DSA:2.170.130.10 47 182 2.6E-9 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_3536 f1334cd121b31eac437f257f8e34bf9a 1052 Pfam PF07715 TonB-dependent Receptor Plug Domain 80 176 9.1E-10 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_3536 f1334cd121b31eac437f257f8e34bf9a 1052 SUPERFAMILY SSF56935 52 1052 1.71E-56 T 13-10-2018 Astex_3536 f1334cd121b31eac437f257f8e34bf9a 1052 Pfam PF00593 TonB dependent receptor 459 1049 6.2E-24 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_3536 f1334cd121b31eac437f257f8e34bf9a 1052 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 52 1052 4.4E-139 T 13-10-2018 IPR010104 Bacterial TonB-dependent receptor Astex_1636 fb1b11f0bdbe339614e2b3f8cb9691fc 252 Gene3D G3DSA:3.30.70.980 83 239 3.1E-46 T 13-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_1636 fb1b11f0bdbe339614e2b3f8cb9691fc 252 Gene3D G3DSA:3.30.70.980 132 208 3.1E-46 T 13-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_1636 fb1b11f0bdbe339614e2b3f8cb9691fc 252 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 242 32.926 T 13-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_1636 fb1b11f0bdbe339614e2b3f8cb9691fc 252 SUPERFAMILY SSF75625 3 249 8.24E-88 T 13-10-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_1636 fb1b11f0bdbe339614e2b3f8cb9691fc 252 Gene3D G3DSA:1.10.10.200 1 81 1.4E-32 T 13-10-2018 IPR017856 Integrase-like, N-terminal Astex_1636 fb1b11f0bdbe339614e2b3f8cb9691fc 252 Pfam PF01709 Transcriptional regulator 5 240 1.1E-88 T 13-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_1636 fb1b11f0bdbe339614e2b3f8cb9691fc 252 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 240 1.4E-86 T 13-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_2312 ca9d1d657485107c99be8d7de599a40e 473 Pfam PF00144 Beta-lactamase 145 453 1.1E-36 T 13-10-2018 IPR001466 Beta-lactamase-related Astex_2312 ca9d1d657485107c99be8d7de599a40e 473 SUPERFAMILY SSF56601 142 450 1.62E-56 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like Astex_2312 ca9d1d657485107c99be8d7de599a40e 473 Gene3D G3DSA:3.40.710.10 132 466 2.3E-55 T 13-10-2018 Astex_0761 868a2ce81a76043d2beaab20b8ce2ab8 183 Gene3D G3DSA:3.60.20.10 7 182 1.1E-67 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Astex_0761 868a2ce81a76043d2beaab20b8ce2ab8 183 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 12 181 5.9E-80 T 13-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 Astex_0761 868a2ce81a76043d2beaab20b8ce2ab8 183 PIRSF PIRSF039093 5 183 1.1E-79 T 13-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 Astex_0761 868a2ce81a76043d2beaab20b8ce2ab8 183 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 11 181 39.637 T 13-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 Astex_0761 868a2ce81a76043d2beaab20b8ce2ab8 183 Pfam PF00227 Proteasome subunit 10 179 1.5E-23 T 13-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 Astex_0761 868a2ce81a76043d2beaab20b8ce2ab8 183 SUPERFAMILY SSF56235 9 181 1.97E-58 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Astex_1197 d4afa8bb4fc6245d69ab2c4c6957e477 96 SUPERFAMILY SSF50129 1 95 5.6E-38 T 13-10-2018 IPR011032 GroES-like superfamily Astex_1197 d4afa8bb4fc6245d69ab2c4c6957e477 96 Hamap MF_00580 10 kDa chaperonin [groS]. 2 95 27.965 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Astex_1197 d4afa8bb4fc6245d69ab2c4c6957e477 96 Gene3D G3DSA:2.30.33.40 1 96 1.2E-41 T 13-10-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 Astex_1197 d4afa8bb4fc6245d69ab2c4c6957e477 96 SMART SM00883 2 94 1.5E-60 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Astex_1197 d4afa8bb4fc6245d69ab2c4c6957e477 96 PRINTS PR00297 10kDa chaperonin signature 3 18 4.5E-35 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Astex_1197 d4afa8bb4fc6245d69ab2c4c6957e477 96 PRINTS PR00297 10kDa chaperonin signature 25 46 4.5E-35 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Astex_1197 d4afa8bb4fc6245d69ab2c4c6957e477 96 PRINTS PR00297 10kDa chaperonin signature 81 94 4.5E-35 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Astex_1197 d4afa8bb4fc6245d69ab2c4c6957e477 96 PRINTS PR00297 10kDa chaperonin signature 60 72 4.5E-35 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Astex_1197 d4afa8bb4fc6245d69ab2c4c6957e477 96 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 13-10-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 Astex_1197 d4afa8bb4fc6245d69ab2c4c6957e477 96 Pfam PF00166 Chaperonin 10 Kd subunit 3 94 1.6E-38 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 Astex_1717 8d4c0d20f0b0cf9459504e005670f87a 214 Gene3D G3DSA:1.10.10.60 11 64 7.6E-22 T 13-10-2018 Astex_1717 8d4c0d20f0b0cf9459504e005670f87a 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 68 3.4E-8 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Astex_1717 8d4c0d20f0b0cf9459504e005670f87a 214 Pfam PF16859 Bacterial transcriptional repressor C-terminal 83 193 1.7E-26 T 13-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal Astex_1717 8d4c0d20f0b0cf9459504e005670f87a 214 SUPERFAMILY SSF48498 87 200 4.85E-20 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily Astex_1717 8d4c0d20f0b0cf9459504e005670f87a 214 Gene3D G3DSA:1.10.357.10 65 204 4.6E-30 T 13-10-2018 Astex_1717 8d4c0d20f0b0cf9459504e005670f87a 214 SUPERFAMILY SSF46689 16 77 2.96E-13 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Astex_1684 c7402c5e3ed36295bcdc8016c4972dc6 347 Gene3D G3DSA:1.10.8.60 185 258 1.0E-24 T 13-10-2018 Astex_1684 c7402c5e3ed36295bcdc8016c4972dc6 347 SMART SM00382 54 187 7.7E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_1684 c7402c5e3ed36295bcdc8016c4972dc6 347 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 254 331 1.0E-24 T 13-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 Astex_1684 c7402c5e3ed36295bcdc8016c4972dc6 347 SUPERFAMILY SSF52540 23 253 6.68E-52 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1684 c7402c5e3ed36295bcdc8016c4972dc6 347 Gene3D G3DSA:3.40.50.300 21 184 4.4E-40 T 13-10-2018 Astex_1684 c7402c5e3ed36295bcdc8016c4972dc6 347 Gene3D G3DSA:1.10.10.10 260 340 4.3E-33 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1684 c7402c5e3ed36295bcdc8016c4972dc6 347 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 27 329 6.6E-135 T 13-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 Astex_1684 c7402c5e3ed36295bcdc8016c4972dc6 347 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 256 329 1.3E-33 T 13-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 Astex_1684 c7402c5e3ed36295bcdc8016c4972dc6 347 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 347 163.485 T 13-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 Astex_1684 c7402c5e3ed36295bcdc8016c4972dc6 347 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 17 237 1.2E-105 T 13-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 Astex_1684 c7402c5e3ed36295bcdc8016c4972dc6 347 SUPERFAMILY SSF46785 260 333 5.58E-24 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_3622 b6617ba6c6529385449a00325c4e934b 269 Gene3D G3DSA:1.10.10.10 27 103 4.3E-18 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_3622 b6617ba6c6529385449a00325c4e934b 269 SUPERFAMILY SSF48008 127 257 2.14E-15 T 13-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal Astex_3622 b6617ba6c6529385449a00325c4e934b 269 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 56 70 1.2E-7 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Astex_3622 b6617ba6c6529385449a00325c4e934b 269 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 70 86 1.2E-7 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Astex_3622 b6617ba6c6529385449a00325c4e934b 269 SMART SM00345 37 96 1.4E-19 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Astex_3622 b6617ba6c6529385449a00325c4e934b 269 SUPERFAMILY SSF46785 30 100 2.04E-17 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_3622 b6617ba6c6529385449a00325c4e934b 269 Gene3D G3DSA:1.20.120.530 125 262 1.5E-16 T 13-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal Astex_3622 b6617ba6c6529385449a00325c4e934b 269 Pfam PF07729 FCD domain 128 252 2.8E-14 T 13-10-2018 IPR011711 GntR, C-terminal Astex_3622 b6617ba6c6529385449a00325c4e934b 269 SMART SM00895 127 253 6.8E-11 T 13-10-2018 IPR011711 GntR, C-terminal Astex_3622 b6617ba6c6529385449a00325c4e934b 269 Pfam PF00392 Bacterial regulatory proteins, gntR family 34 96 4.1E-19 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Astex_0470 0bc7b4d7c2f5d7cfeef8388ed921a85e 142 Pfam PF07475 HPr Serine kinase C-terminal domain 21 80 1.3E-13 T 13-10-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 Astex_0470 0bc7b4d7c2f5d7cfeef8388ed921a85e 142 SUPERFAMILY SSF53795 3 104 8.85E-16 T 13-10-2018 Astex_0470 0bc7b4d7c2f5d7cfeef8388ed921a85e 142 Gene3D G3DSA:3.40.50.300 2 140 7.5E-25 T 13-10-2018 Astex_2507 2d4ae39afb89284853e5fb81d7412ef2 201 Pfam PF11159 Protein of unknown function (DUF2939) 14 116 2.1E-24 T 13-10-2018 IPR021330 Protein of unknown function DUF2939 Astex_0487 4d8f70909b01d206132ae37e15c32885 986 Pfam PF13307 Helicase C-terminal domain 817 951 1.1E-13 T 13-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 Astex_0487 4d8f70909b01d206132ae37e15c32885 986 SUPERFAMILY SSF52540 263 951 1.69E-14 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0487 4d8f70909b01d206132ae37e15c32885 986 Gene3D G3DSA:3.40.50.300 240 508 6.8E-29 T 13-10-2018 Astex_0487 4d8f70909b01d206132ae37e15c32885 986 Gene3D G3DSA:3.40.50.300 795 970 2.8E-20 T 13-10-2018 Astex_0487 4d8f70909b01d206132ae37e15c32885 986 SMART SM00491 828 955 1.2E-6 T 13-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 Astex_1531 756d8603ccf800c1e8c51bde160c6fdd 593 SUPERFAMILY SSF55874 292 449 1.44E-33 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_1531 756d8603ccf800c1e8c51bde160c6fdd 593 SMART SM00387 340 451 2.0E-26 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_1531 756d8603ccf800c1e8c51bde160c6fdd 593 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 340 450 9.2E-21 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_1531 756d8603ccf800c1e8c51bde160c6fdd 593 PRINTS PR00344 Bacterial sensor protein C-terminal signature 411 429 8.7E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1531 756d8603ccf800c1e8c51bde160c6fdd 593 PRINTS PR00344 Bacterial sensor protein C-terminal signature 377 391 8.7E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1531 756d8603ccf800c1e8c51bde160c6fdd 593 PRINTS PR00344 Bacterial sensor protein C-terminal signature 435 448 8.7E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1531 756d8603ccf800c1e8c51bde160c6fdd 593 Gene3D G3DSA:3.30.565.10 291 451 5.6E-36 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_0485 fbbbfe2abdac87e2a6bff87065ab46f8 273 Pfam PF09608 Putative transmembrane protein (Alph_Pro_TM) 33 272 3.5E-75 T 13-10-2018 IPR019088 Conserved hypothetical protein CHP02186-related, transmembrane Astex_1805 b14905d5f8960ef2f1a2cc556a5ab242 184 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 178 7.7E-32 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 Astex_1805 b14905d5f8960ef2f1a2cc556a5ab242 184 Pfam PF08281 Sigma-70, region 4 124 175 2.3E-16 T 13-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Astex_1805 b14905d5f8960ef2f1a2cc556a5ab242 184 SUPERFAMILY SSF88659 117 179 1.55E-14 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Astex_1805 b14905d5f8960ef2f1a2cc556a5ab242 184 Gene3D G3DSA:1.10.1740.10 7 89 4.3E-25 T 13-10-2018 Astex_1805 b14905d5f8960ef2f1a2cc556a5ab242 184 SUPERFAMILY SSF88946 3 111 9.26E-28 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 Astex_1805 b14905d5f8960ef2f1a2cc556a5ab242 184 Pfam PF04542 Sigma-70 region 2 25 90 3.8E-20 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 Astex_1805 b14905d5f8960ef2f1a2cc556a5ab242 184 Gene3D G3DSA:1.10.10.10 98 182 1.7E-18 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_2697 1fe8cc698bf05ba87d6ce09b4842c4c4 467 Pfam PF13360 PQQ-like domain 138 374 2.0E-68 T 13-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat Astex_2697 1fe8cc698bf05ba87d6ce09b4842c4c4 467 SUPERFAMILY SSF50998 346 464 8.63E-16 T 13-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily Astex_2697 1fe8cc698bf05ba87d6ce09b4842c4c4 467 SUPERFAMILY SSF50998 75 380 2.67E-64 T 13-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily Astex_2697 1fe8cc698bf05ba87d6ce09b4842c4c4 467 Gene3D G3DSA:2.130.10.10 87 467 1.4E-84 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 Astex_2697 1fe8cc698bf05ba87d6ce09b4842c4c4 467 SMART SM00564 212 243 0.012 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Astex_2697 1fe8cc698bf05ba87d6ce09b4842c4c4 467 SMART SM00564 172 203 73.0 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Astex_2697 1fe8cc698bf05ba87d6ce09b4842c4c4 467 SMART SM00564 125 156 0.07 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Astex_2697 1fe8cc698bf05ba87d6ce09b4842c4c4 467 SMART SM00564 308 339 3.6E-5 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Astex_2697 1fe8cc698bf05ba87d6ce09b4842c4c4 467 SMART SM00564 257 288 0.11 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Astex_2697 1fe8cc698bf05ba87d6ce09b4842c4c4 467 SMART SM00564 407 438 15.0 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Astex_2697 1fe8cc698bf05ba87d6ce09b4842c4c4 467 SMART SM00564 346 377 9.7 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat Astex_1744 9a48932eb7ba7110033327190f7c7480 350 SUPERFAMILY SSF55781 65 204 2.16E-7 T 13-10-2018 Astex_1744 9a48932eb7ba7110033327190f7c7480 350 Gene3D G3DSA:3.30.450.40 18 205 1.1E-51 T 13-10-2018 IPR029016 GAF-like domain superfamily Astex_1744 9a48932eb7ba7110033327190f7c7480 350 Gene3D G3DSA:1.10.10.60 296 347 8.8E-16 T 13-10-2018 Astex_1744 9a48932eb7ba7110033327190f7c7480 350 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 330 350 4.0E-7 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Astex_1744 9a48932eb7ba7110033327190f7c7480 350 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 313 330 4.0E-7 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Astex_1744 9a48932eb7ba7110033327190f7c7480 350 SUPERFAMILY SSF46689 303 343 7.77E-12 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Astex_1744 9a48932eb7ba7110033327190f7c7480 350 Pfam PF02954 Bacterial regulatory protein, Fis family 307 343 1.4E-13 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Astex_1744 9a48932eb7ba7110033327190f7c7480 350 Pfam PF01590 GAF domain 106 200 2.7E-7 T 13-10-2018 IPR003018 GAF domain GO:0005515 Astex_2930 c9011b4faaea9b4b56e0387e05ff142c 378 Pfam PF02504 Fatty acid synthesis protein 25 346 3.2E-101 T 13-10-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 Astex_2930 c9011b4faaea9b4b56e0387e05ff142c 378 PIRSF PIRSF002465 23 363 4.4E-115 T 13-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 Astex_2930 c9011b4faaea9b4b56e0387e05ff142c 378 Gene3D G3DSA:3.40.718.10 24 369 5.0E-113 T 13-10-2018 Astex_2930 c9011b4faaea9b4b56e0387e05ff142c 378 Hamap MF_00019 Phosphate acyltransferase [plsX]. 24 367 124.282 T 13-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 Astex_2930 c9011b4faaea9b4b56e0387e05ff142c 378 SUPERFAMILY SSF53659 25 358 4.93E-92 T 13-10-2018 Astex_2930 c9011b4faaea9b4b56e0387e05ff142c 378 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 27 359 1.8E-92 T 13-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 Astex_3221 1602a9f5cdf388f22a144cb14be6a305 390 PRINTS PR00344 Bacterial sensor protein C-terminal signature 374 387 2.9E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_3221 1602a9f5cdf388f22a144cb14be6a305 390 PRINTS PR00344 Bacterial sensor protein C-terminal signature 350 368 2.9E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_3221 1602a9f5cdf388f22a144cb14be6a305 390 PRINTS PR00344 Bacterial sensor protein C-terminal signature 321 335 2.9E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_3221 1602a9f5cdf388f22a144cb14be6a305 390 PRINTS PR00344 Bacterial sensor protein C-terminal signature 339 349 2.9E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_3221 1602a9f5cdf388f22a144cb14be6a305 390 Gene3D G3DSA:1.10.287.130 176 236 1.9E-34 T 13-10-2018 Astex_3221 1602a9f5cdf388f22a144cb14be6a305 390 SUPERFAMILY SSF55874 227 388 3.27E-31 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_3221 1602a9f5cdf388f22a144cb14be6a305 390 SMART SM00387 281 390 1.7E-22 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_3221 1602a9f5cdf388f22a144cb14be6a305 390 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 282 388 9.4E-14 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_3221 1602a9f5cdf388f22a144cb14be6a305 390 Gene3D G3DSA:3.30.565.10 237 387 1.9E-34 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_1217 a420f87e1176960104df7965d87ad9d2 1002 Gene3D G3DSA:2.60.120.260 177 282 3.8E-7 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_1217 a420f87e1176960104df7965d87ad9d2 1002 SUPERFAMILY SSF49785 188 273 1.7E-5 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_1217 a420f87e1176960104df7965d87ad9d2 1002 Gene3D G3DSA:1.50.10.10 574 804 3.0E-11 T 13-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 Astex_1217 a420f87e1176960104df7965d87ad9d2 1002 SUPERFAMILY SSF48208 573 900 1.47E-15 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 Astex_2705 2d2eeed87f7850840be5a47b78f98efa 491 Gene3D G3DSA:3.40.50.300 174 482 4.5E-99 T 13-10-2018 Astex_2705 2d2eeed87f7850840be5a47b78f98efa 491 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 20 482 3.4E-150 T 13-10-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 Astex_2705 2d2eeed87f7850840be5a47b78f98efa 491 SUPERFAMILY SSF52540 194 474 1.04E-46 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2705 2d2eeed87f7850840be5a47b78f98efa 491 Gene3D G3DSA:1.10.860.10 14 173 6.1E-38 T 13-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal Astex_2705 2d2eeed87f7850840be5a47b78f98efa 491 SUPERFAMILY SSF48024 19 129 2.22E-29 T 13-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 Astex_2705 2d2eeed87f7850840be5a47b78f98efa 491 Pfam PF00772 DnaB-like helicase N terminal domain 20 121 1.4E-26 T 13-10-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 Astex_2705 2d2eeed87f7850840be5a47b78f98efa 491 Pfam PF03796 DnaB-like helicase C terminal domain 195 480 1.3E-98 T 13-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 Astex_2705 2d2eeed87f7850840be5a47b78f98efa 491 SMART SM00382 212 423 0.0013 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_2107 6d51b6338716c202c9b9ea5b2a00f19a 642 SUPERFAMILY SSF55021 565 639 3.63E-15 T 13-10-2018 Astex_2107 6d51b6338716c202c9b9ea5b2a00f19a 642 SUPERFAMILY SSF56784 12 229 1.06E-30 T 13-10-2018 IPR036412 HAD-like superfamily Astex_2107 6d51b6338716c202c9b9ea5b2a00f19a 642 Gene3D G3DSA:3.40.50.720 342 530 3.0E-106 T 13-10-2018 Astex_2107 6d51b6338716c202c9b9ea5b2a00f19a 642 SUPERFAMILY SSF51735 341 528 7.76E-56 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_2107 6d51b6338716c202c9b9ea5b2a00f19a 642 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 387 414 - T 13-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 Astex_2107 6d51b6338716c202c9b9ea5b2a00f19a 642 Gene3D G3DSA:3.30.70.260 561 641 6.9E-28 T 13-10-2018 Astex_2107 6d51b6338716c202c9b9ea5b2a00f19a 642 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 462 478 - T 13-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site Astex_2107 6d51b6338716c202c9b9ea5b2a00f19a 642 Gene3D G3DSA:3.40.50.720 248 544 3.0E-106 T 13-10-2018 Astex_2107 6d51b6338716c202c9b9ea5b2a00f19a 642 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 351 527 2.2E-53 T 13-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 Astex_2107 6d51b6338716c202c9b9ea5b2a00f19a 642 Gene3D G3DSA:3.40.50.1000 14 207 1.1E-48 T 13-10-2018 IPR023214 HAD superfamily Astex_2107 6d51b6338716c202c9b9ea5b2a00f19a 642 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 248 559 1.1E-33 T 13-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 Astex_2107 6d51b6338716c202c9b9ea5b2a00f19a 642 Pfam PF12710 haloacid dehalogenase-like hydrolase 14 187 4.8E-10 T 13-10-2018 Astex_2107 6d51b6338716c202c9b9ea5b2a00f19a 642 SUPERFAMILY SSF52283 242 368 1.12E-41 T 13-10-2018 Astex_2107 6d51b6338716c202c9b9ea5b2a00f19a 642 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 14 188 2.7E-17 T 13-10-2018 Astex_2107 6d51b6338716c202c9b9ea5b2a00f19a 642 Gene3D G3DSA:1.10.150.210 26 87 1.1E-48 T 13-10-2018 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 Astex_2617 8fe1e38bd692a8d70c7ef2927801829d 339 Gene3D G3DSA:1.10.357.140 49 217 7.0E-15 T 13-10-2018 Astex_2617 8fe1e38bd692a8d70c7ef2927801829d 339 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 41 334 2.9E-96 T 13-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 Astex_2617 8fe1e38bd692a8d70c7ef2927801829d 339 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 38 335 19.366 T 13-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 Astex_2617 8fe1e38bd692a8d70c7ef2927801829d 339 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 92 114 - T 13-10-2018 IPR030470 UbiA prenyltransferase conserved site Astex_2617 8fe1e38bd692a8d70c7ef2927801829d 339 Pfam PF01040 UbiA prenyltransferase family 55 293 2.6E-57 T 13-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 Astex_1781 c383f5337e118bfac66b2325539ba42c 475 Pfam PF08245 Mur ligase middle domain 120 305 3.9E-25 T 13-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Astex_1781 c383f5337e118bfac66b2325539ba42c 475 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 14 472 41.265 T 13-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Astex_1781 c383f5337e118bfac66b2325539ba42c 475 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 17 463 5.8E-156 T 13-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Astex_1781 c383f5337e118bfac66b2325539ba42c 475 Gene3D G3DSA:3.40.1190.10 104 323 1.1E-69 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Astex_1781 c383f5337e118bfac66b2325539ba42c 475 Gene3D G3DSA:3.40.50.720 16 103 6.7E-32 T 13-10-2018 Astex_1781 c383f5337e118bfac66b2325539ba42c 475 Gene3D G3DSA:3.90.190.20 324 472 1.5E-50 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Astex_1781 c383f5337e118bfac66b2325539ba42c 475 SUPERFAMILY SSF53244 324 469 1.03E-45 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Astex_1781 c383f5337e118bfac66b2325539ba42c 475 SUPERFAMILY SSF51984 16 102 2.09E-26 T 13-10-2018 Astex_1781 c383f5337e118bfac66b2325539ba42c 475 Pfam PF02875 Mur ligase family, glutamate ligase domain 325 410 1.2E-19 T 13-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Astex_1781 c383f5337e118bfac66b2325539ba42c 475 Pfam PF01225 Mur ligase family, catalytic domain 17 114 6.0E-28 T 13-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 Astex_1781 c383f5337e118bfac66b2325539ba42c 475 SUPERFAMILY SSF53623 101 323 7.72E-66 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Astex_1833 d6fa337d120bcf6cc67fddbea2f0b206 275 Gene3D G3DSA:1.10.3130.10 3 148 1.0E-50 T 13-10-2018 Astex_1833 d6fa337d120bcf6cc67fddbea2f0b206 275 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 199 233 3.9E-8 T 13-10-2018 IPR001451 Hexapeptide repeat Astex_1833 d6fa337d120bcf6cc67fddbea2f0b206 275 PIRSF PIRSF000441 81 270 9.9E-61 T 13-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 Astex_1833 d6fa337d120bcf6cc67fddbea2f0b206 275 SMART SM00971 15 119 1.6E-45 T 13-10-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 Astex_1833 d6fa337d120bcf6cc67fddbea2f0b206 275 Pfam PF06426 Serine acetyltransferase, N-terminal 15 118 1.1E-34 T 13-10-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 Astex_1833 d6fa337d120bcf6cc67fddbea2f0b206 275 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 88 248 1.4E-68 T 13-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 Astex_1833 d6fa337d120bcf6cc67fddbea2f0b206 275 SUPERFAMILY SSF51161 13 250 5.41E-60 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily Astex_1833 d6fa337d120bcf6cc67fddbea2f0b206 275 Gene3D G3DSA:2.160.10.10 149 272 2.3E-35 T 13-10-2018 Astex_1833 d6fa337d120bcf6cc67fddbea2f0b206 275 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 208 236 - T 13-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 Astex_1085 20d795233c9609dfb3c34a0cbed344a4 621 TIGRFAM TIGR01651 CobT: cobaltochelatase, CobT subunit 10 614 1.4E-263 T 13-10-2018 IPR006538 Cobalt chelatase, CobT subunit GO:0009236 KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 Astex_1085 20d795233c9609dfb3c34a0cbed344a4 621 Pfam PF11775 Cobalamin biosynthesis protein CobT VWA domain 396 613 2.9E-106 T 13-10-2018 IPR025861 Cobalamin biosynthesis protein CobT VWA domain KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 Astex_1085 20d795233c9609dfb3c34a0cbed344a4 621 SMART SM00327 407 609 6.9E-6 T 13-10-2018 IPR002035 von Willebrand factor, type A Astex_1085 20d795233c9609dfb3c34a0cbed344a4 621 PIRSF PIRSF031715 1 621 4.9E-247 T 13-10-2018 IPR006538 Cobalt chelatase, CobT subunit GO:0009236 KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 Astex_1085 20d795233c9609dfb3c34a0cbed344a4 621 SUPERFAMILY SSF53300 410 603 3.8E-15 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Astex_1085 20d795233c9609dfb3c34a0cbed344a4 621 Pfam PF06213 Cobalamin biosynthesis protein CobT 9 275 4.5E-82 T 13-10-2018 IPR006538 Cobalt chelatase, CobT subunit GO:0009236 KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 Astex_1085 20d795233c9609dfb3c34a0cbed344a4 621 Gene3D G3DSA:3.40.50.410 407 604 3.2E-8 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Astex_3156 1b185df72a8bc890f78182f25191e540 487 Pfam PF01943 Polysaccharide biosynthesis protein 3 273 3.4E-14 T 13-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 Astex_3156 1b185df72a8bc890f78182f25191e540 487 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 333 466 9.3E-18 T 13-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain Astex_3342 1eb2e3ca554a154d12837a0d977da75b 307 Gene3D G3DSA:3.40.190.10 173 271 1.6E-52 T 13-10-2018 Astex_3342 1eb2e3ca554a154d12837a0d977da75b 307 Gene3D G3DSA:1.10.10.10 1 91 5.4E-30 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_3342 1eb2e3ca554a154d12837a0d977da75b 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 70 3.7E-18 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_3342 1eb2e3ca554a154d12837a0d977da75b 307 SUPERFAMILY SSF53850 92 300 4.71E-41 T 13-10-2018 Astex_3342 1eb2e3ca554a154d12837a0d977da75b 307 SUPERFAMILY SSF46785 8 90 2.26E-19 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_3342 1eb2e3ca554a154d12837a0d977da75b 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 58 1.1E-5 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_3342 1eb2e3ca554a154d12837a0d977da75b 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 47 1.1E-5 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_3342 1eb2e3ca554a154d12837a0d977da75b 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 26 37 1.1E-5 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_3342 1eb2e3ca554a154d12837a0d977da75b 307 Pfam PF03466 LysR substrate binding domain 96 300 1.8E-28 T 13-10-2018 IPR005119 LysR, substrate-binding Astex_3342 1eb2e3ca554a154d12837a0d977da75b 307 Gene3D G3DSA:3.40.190.10 94 295 1.6E-52 T 13-10-2018 Astex_0775 e9ab1454fa8856048a7a0f32a3ce4720 201 Pfam PF01713 Smr domain 116 197 1.5E-20 T 13-10-2018 IPR002625 Smr domain Astex_0775 e9ab1454fa8856048a7a0f32a3ce4720 201 Gene3D G3DSA:3.30.1370.110 77 201 2.1E-33 T 13-10-2018 Astex_0775 e9ab1454fa8856048a7a0f32a3ce4720 201 SUPERFAMILY SSF160443 113 197 7.19E-14 T 13-10-2018 IPR036063 Smr domain superfamily Astex_0775 e9ab1454fa8856048a7a0f32a3ce4720 201 SMART SM00463 113 197 7.4E-8 T 13-10-2018 IPR002625 Smr domain Astex_0629 802f19bdbf1771bc1036d50433667a89 405 Gene3D G3DSA:1.20.1250.20 18 393 5.0E-44 T 13-10-2018 Astex_0629 802f19bdbf1771bc1036d50433667a89 405 Pfam PF07690 Major Facilitator Superfamily 26 203 8.0E-25 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Astex_0629 802f19bdbf1771bc1036d50433667a89 405 Pfam PF07690 Major Facilitator Superfamily 225 398 8.8E-13 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Astex_0629 802f19bdbf1771bc1036d50433667a89 405 SUPERFAMILY SSF103473 11 397 7.72E-52 T 13-10-2018 IPR036259 MFS transporter superfamily Astex_3186 1afe4e209e3b2a749206cddaa461e215 167 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 20 161 1.7E-25 T 13-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 Astex_3186 1afe4e209e3b2a749206cddaa461e215 167 SMART SM00732 17 128 1.9E-28 T 13-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 Astex_3186 1afe4e209e3b2a749206cddaa461e215 167 SUPERFAMILY SSF53098 18 163 2.43E-32 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily Astex_3186 1afe4e209e3b2a749206cddaa461e215 167 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 17 164 23.561 T 13-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 Astex_3186 1afe4e209e3b2a749206cddaa461e215 167 Gene3D G3DSA:3.30.420.140 17 167 9.7E-36 T 13-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 Astex_3186 1afe4e209e3b2a749206cddaa461e215 167 Pfam PF03652 Holliday junction resolvase 19 161 8.4E-35 T 13-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 Astex_2226 69f2c8538a79f7eff92f86a26b171440 358 Pfam PF00483 Nucleotidyl transferase 5 282 2.3E-52 T 13-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Astex_2226 69f2c8538a79f7eff92f86a26b171440 358 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 3 346 1.5E-113 T 13-10-2018 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 Astex_2226 69f2c8538a79f7eff92f86a26b171440 358 SUPERFAMILY SSF159283 282 343 6.02E-14 T 13-10-2018 Astex_2226 69f2c8538a79f7eff92f86a26b171440 358 Gene3D G3DSA:3.90.550.10 1 349 4.7E-101 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_2226 69f2c8538a79f7eff92f86a26b171440 358 SUPERFAMILY SSF53448 1 279 5.63E-59 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_3673 2ae893dbfd0c1580293f4edb0c102e35 126 TIGRFAM TIGR01550 DOC_P1: death-on-curing family protein 27 114 6.1E-15 T 13-10-2018 IPR006440 Death on curing protein GO:0016301 Astex_3673 2ae893dbfd0c1580293f4edb0c102e35 126 SUPERFAMILY SSF140931 52 117 1.57E-7 T 13-10-2018 IPR036597 Fido-like domain superfamily Astex_3673 2ae893dbfd0c1580293f4edb0c102e35 126 PIRSF PIRSF018297 2 126 1.1E-35 T 13-10-2018 IPR006440 Death on curing protein GO:0016301 Astex_3673 2ae893dbfd0c1580293f4edb0c102e35 126 Gene3D G3DSA:1.20.120.1870 4 126 2.4E-33 T 13-10-2018 Astex_3673 2ae893dbfd0c1580293f4edb0c102e35 126 Pfam PF02661 Fic/DOC family 5 86 6.4E-11 T 13-10-2018 IPR003812 Fido domain Astex_3630 068cd99741b00af2b843f309f617e33f 297 Gene3D G3DSA:3.40.190.10 162 264 1.1E-57 T 13-10-2018 Astex_3630 068cd99741b00af2b843f309f617e33f 297 SUPERFAMILY SSF46785 1 86 5.21E-21 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_3630 068cd99741b00af2b843f309f617e33f 297 Gene3D G3DSA:3.40.190.10 91 292 1.1E-57 T 13-10-2018 Astex_3630 068cd99741b00af2b843f309f617e33f 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 4.3E-17 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_3630 068cd99741b00af2b843f309f617e33f 297 SUPERFAMILY SSF53850 88 296 4.89E-39 T 13-10-2018 Astex_3630 068cd99741b00af2b843f309f617e33f 297 Gene3D G3DSA:1.10.10.10 1 88 6.8E-24 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_3630 068cd99741b00af2b843f309f617e33f 297 Pfam PF03466 LysR substrate binding domain 87 296 9.3E-40 T 13-10-2018 IPR005119 LysR, substrate-binding Astex_3451 544b8dbae290fc961261b8f9655b598c 370 Gene3D G3DSA:3.40.50.1970 6 174 5.1E-63 T 13-10-2018 Astex_3451 544b8dbae290fc961261b8f9655b598c 370 PIRSF PIRSF001455 12 368 2.3E-111 T 13-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 Astex_3451 544b8dbae290fc961261b8f9655b598c 370 SUPERFAMILY SSF56796 12 363 2.36E-113 T 13-10-2018 Astex_3451 544b8dbae290fc961261b8f9655b598c 370 Pfam PF01761 3-dehydroquinate synthase 69 332 2.8E-106 T 13-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 Astex_3451 544b8dbae290fc961261b8f9655b598c 370 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 14 360 2.4E-122 T 13-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 Astex_3451 544b8dbae290fc961261b8f9655b598c 370 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 1 363 69.919 T 13-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 Astex_3451 544b8dbae290fc961261b8f9655b598c 370 Gene3D G3DSA:1.20.1090.10 175 365 7.1E-64 T 13-10-2018 Astex_1509 c2ff864244a38974a75dddbd6651bcaf 456 Pfam PF01554 MatE 19 175 9.5E-24 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 Astex_1509 c2ff864244a38974a75dddbd6651bcaf 456 Pfam PF01554 MatE 250 408 7.9E-21 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 Astex_1509 c2ff864244a38974a75dddbd6651bcaf 456 PIRSF PIRSF006603 7 453 4.0E-52 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 Astex_1509 c2ff864244a38974a75dddbd6651bcaf 456 TIGRFAM TIGR00797 matE: MATE efflux family protein 19 420 1.1E-54 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 Astex_0415 f45726fbbe7c644325fa6404e2b6279f 397 PIRSF PIRSF000390 3 397 1.6E-102 T 13-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase Astex_0415 f45726fbbe7c644325fa6404e2b6279f 397 SUPERFAMILY SSF53383 6 396 1.57E-99 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Astex_0415 f45726fbbe7c644325fa6404e2b6279f 397 Gene3D G3DSA:3.90.1150.10 270 397 5.3E-29 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Astex_0415 f45726fbbe7c644325fa6404e2b6279f 397 TIGRFAM TIGR03588 PseC: UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase 6 396 7.2E-139 T 13-10-2018 IPR020026 UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase Astex_0415 f45726fbbe7c644325fa6404e2b6279f 397 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 14 392 5.3E-104 T 13-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase Astex_0415 f45726fbbe7c644325fa6404e2b6279f 397 Gene3D G3DSA:3.40.640.10 2 269 5.5E-84 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Astex_0597 b7a79b4c80f4a78f1d19167d7fbd9653 456 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 422 442 3.1E-7 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Astex_0597 b7a79b4c80f4a78f1d19167d7fbd9653 456 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 405 422 3.1E-7 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Astex_0597 b7a79b4c80f4a78f1d19167d7fbd9653 456 Pfam PF02954 Bacterial regulatory protein, Fis family 399 439 1.1E-13 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Astex_0597 b7a79b4c80f4a78f1d19167d7fbd9653 456 SMART SM00382 140 289 3.8E-7 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_0597 b7a79b4c80f4a78f1d19167d7fbd9653 456 SUPERFAMILY SSF52172 13 164 2.72E-12 T 13-10-2018 IPR011006 CheY-like superfamily Astex_0597 b7a79b4c80f4a78f1d19167d7fbd9653 456 Gene3D G3DSA:3.40.50.300 113 291 8.9E-67 T 13-10-2018 Astex_0597 b7a79b4c80f4a78f1d19167d7fbd9653 456 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 144 157 - T 13-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 Astex_0597 b7a79b4c80f4a78f1d19167d7fbd9653 456 Pfam PF00158 Sigma-54 interaction domain 120 286 9.1E-69 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 Astex_0597 b7a79b4c80f4a78f1d19167d7fbd9653 456 Gene3D G3DSA:1.10.10.60 376 440 2.3E-13 T 13-10-2018 Astex_0597 b7a79b4c80f4a78f1d19167d7fbd9653 456 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 333 342 - T 13-10-2018 IPR025944 Sigma-54 interaction domain, conserved site Astex_0597 b7a79b4c80f4a78f1d19167d7fbd9653 456 SUPERFAMILY SSF52540 120 361 2.3E-70 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0597 b7a79b4c80f4a78f1d19167d7fbd9653 456 SUPERFAMILY SSF46689 333 439 1.76E-11 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Astex_0597 b7a79b4c80f4a78f1d19167d7fbd9653 456 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 206 221 - T 13-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 Astex_0597 b7a79b4c80f4a78f1d19167d7fbd9653 456 Gene3D G3DSA:1.10.8.60 292 367 7.3E-21 T 13-10-2018 Astex_0597 b7a79b4c80f4a78f1d19167d7fbd9653 456 Gene3D G3DSA:3.40.50.2300 1 112 8.4E-7 T 13-10-2018 Astex_3479 c48f71cda0673743817c1eb6b58adcf7 295 SUPERFAMILY SSF75005 34 226 5.72E-16 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Astex_3479 c48f71cda0673743817c1eb6b58adcf7 295 Gene3D G3DSA:2.115.10.20 55 199 4.1E-10 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Astex_3207 f9e890d4f5c0624b8acc6c57f354c141 955 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 72 216 3.7E-13 T 13-10-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_3207 f9e890d4f5c0624b8acc6c57f354c141 955 Gene3D G3DSA:2.60.120.260 46 218 1.3E-36 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_3207 f9e890d4f5c0624b8acc6c57f354c141 955 ProSitePatterns PS00608 Glycosyl hydrolases family 2 acid/base catalyst. 432 446 - T 13-10-2018 IPR023232 Glycoside hydrolase, family 2, active site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_3207 f9e890d4f5c0624b8acc6c57f354c141 955 Gene3D G3DSA:2.60.40.10 621 698 2.4E-25 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_3207 f9e890d4f5c0624b8acc6c57f354c141 955 Gene3D G3DSA:3.20.20.80 334 620 3.2E-96 T 13-10-2018 Astex_3207 f9e890d4f5c0624b8acc6c57f354c141 955 SUPERFAMILY SSF51445 336 618 5.15E-70 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_3207 f9e890d4f5c0624b8acc6c57f354c141 955 Pfam PF00703 Glycosyl hydrolases family 2 222 331 9.5E-15 T 13-10-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_3207 f9e890d4f5c0624b8acc6c57f354c141 955 Pfam PF16355 Domain of unknown function (DUF4982) 634 691 2.8E-17 T 13-10-2018 IPR032311 Domain of unknown function DUF4982 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_3207 f9e890d4f5c0624b8acc6c57f354c141 955 SUPERFAMILY SSF49303 222 331 2.22E-16 T 13-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily Astex_3207 f9e890d4f5c0624b8acc6c57f354c141 955 PRINTS PR00132 Glycosyl hydrolase family 2 signature 343 357 5.5E-7 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_3207 f9e890d4f5c0624b8acc6c57f354c141 955 PRINTS PR00132 Glycosyl hydrolase family 2 signature 150 165 5.5E-7 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_3207 f9e890d4f5c0624b8acc6c57f354c141 955 PRINTS PR00132 Glycosyl hydrolase family 2 signature 432 447 5.5E-7 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_3207 f9e890d4f5c0624b8acc6c57f354c141 955 Gene3D G3DSA:2.60.40.10 220 331 4.1E-22 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_3207 f9e890d4f5c0624b8acc6c57f354c141 955 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 338 414 1.3E-14 T 13-10-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 Astex_3207 f9e890d4f5c0624b8acc6c57f354c141 955 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 420 574 2.8E-12 T 13-10-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 Astex_3207 f9e890d4f5c0624b8acc6c57f354c141 955 Gene3D G3DSA:2.60.40.10 702 813 4.2E-26 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_3207 f9e890d4f5c0624b8acc6c57f354c141 955 SUPERFAMILY SSF49785 43 218 3.52E-33 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_1257 fa8d6197dcae6f8683117fae10117489 260 Gene3D G3DSA:2.60.40.10 43 110 1.0E-5 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_1190 eb5f5b6da7bf96e706b1b46a0b3b4f9b 150 Pfam PF11164 Protein of unknown function (DUF2948) 12 148 1.2E-35 T 13-10-2018 IPR021335 Protein of unknown function DUF2948 Astex_2585 0552d78b743391f5ef756380316c6f7a 903 Gene3D G3DSA:2.170.130.10 47 167 7.3E-14 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_2585 0552d78b743391f5ef756380316c6f7a 903 Pfam PF07715 TonB-dependent Receptor Plug Domain 63 163 1.5E-12 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_2585 0552d78b743391f5ef756380316c6f7a 903 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 47 902 9.8E-151 T 13-10-2018 IPR010104 Bacterial TonB-dependent receptor Astex_2585 0552d78b743391f5ef756380316c6f7a 903 SUPERFAMILY SSF56935 41 903 5.19E-76 T 13-10-2018 Astex_0444 a6379383db5e024e01c57cdaf5fd47fc 209 Gene3D G3DSA:3.40.50.300 2 195 2.7E-37 T 13-10-2018 Astex_0444 a6379383db5e024e01c57cdaf5fd47fc 209 SMART SM00382 29 205 2.7E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_0444 a6379383db5e024e01c57cdaf5fd47fc 209 SUPERFAMILY SSF52540 5 189 6.31E-36 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0444 a6379383db5e024e01c57cdaf5fd47fc 209 Pfam PF00005 ABC transporter 21 157 1.4E-20 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_0444 a6379383db5e024e01c57cdaf5fd47fc 209 TIGRFAM TIGR01189 ccmA: heme ABC exporter, ATP-binding protein CcmA 5 199 8.5E-51 T 13-10-2018 IPR005895 ABC transporter, haem export, CcmA GO:0005215|GO:0017004 Astex_0157 7d205b81818a1a03c99a6de5f995aace 136 SUPERFAMILY SSF161084 5 127 3.73E-14 T 13-10-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamily Astex_0157 7d205b81818a1a03c99a6de5f995aace 136 Pfam PF01124 MAPEG family 2 130 5.7E-18 T 13-10-2018 IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein Astex_0157 7d205b81818a1a03c99a6de5f995aace 136 Gene3D G3DSA:1.20.120.550 2 134 8.0E-9 T 13-10-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamily Astex_2723 f38930c0003430f742ed358b8d8a63b2 893 SUPERFAMILY SSF49303 813 889 9.35E-17 T 13-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily Astex_2723 f38930c0003430f742ed358b8d8a63b2 893 Gene3D G3DSA:2.60.40.10 250 356 1.2E-21 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_2723 f38930c0003430f742ed358b8d8a63b2 893 SUPERFAMILY SSF49785 45 248 3.4E-50 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_2723 f38930c0003430f742ed358b8d8a63b2 893 SUPERFAMILY SSF49303 712 811 1.15E-16 T 13-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily Astex_2723 f38930c0003430f742ed358b8d8a63b2 893 SUPERFAMILY SSF49303 250 357 2.41E-24 T 13-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily Astex_2723 f38930c0003430f742ed358b8d8a63b2 893 SUPERFAMILY SSF51445 355 711 3.96E-103 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_2723 f38930c0003430f742ed358b8d8a63b2 893 Gene3D G3DSA:2.60.120.260 38 248 3.5E-58 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_2723 f38930c0003430f742ed358b8d8a63b2 893 Gene3D G3DSA:2.60.40.10 808 893 2.2E-15 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_2723 f38930c0003430f742ed358b8d8a63b2 893 Gene3D G3DSA:3.20.20.80 357 709 1.0E-116 T 13-10-2018 Astex_2723 f38930c0003430f742ed358b8d8a63b2 893 Pfam PF00703 Glycosyl hydrolases family 2 250 358 6.3E-12 T 13-10-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_3371 09c904e7702bfd71463360b00c628c72 266 SMART SM00382 44 240 4.9E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_3371 09c904e7702bfd71463360b00c628c72 266 Pfam PF00005 ABC transporter 37 190 4.1E-31 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_3371 09c904e7702bfd71463360b00c628c72 266 SUPERFAMILY SSF52540 12 254 7.57E-60 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_3371 09c904e7702bfd71463360b00c628c72 266 Gene3D G3DSA:3.40.50.300 17 263 1.9E-67 T 13-10-2018 Astex_3371 09c904e7702bfd71463360b00c628c72 266 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 20 266 1.7E-116 T 13-10-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 Astex_3371 09c904e7702bfd71463360b00c628c72 266 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Astex_3819 40afec31ce329700df2a5871c08e9793 163 Gene3D G3DSA:3.40.50.2300 3 143 6.9E-36 T 13-10-2018 Astex_3819 40afec31ce329700df2a5871c08e9793 163 SMART SM00226 5 143 2.7E-28 T 13-10-2018 IPR023485 Phosphotyrosine protein phosphatase I Astex_3819 40afec31ce329700df2a5871c08e9793 163 SUPERFAMILY SSF52788 4 143 2.35E-36 T 13-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily Astex_3819 40afec31ce329700df2a5871c08e9793 163 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 7 138 1.2E-14 T 13-10-2018 IPR023485 Phosphotyrosine protein phosphatase I Astex_0922 84f41795f048ebe1463e6d96f9eec79e 573 Pfam PF00005 ABC transporter 386 531 1.0E-24 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_0922 84f41795f048ebe1463e6d96f9eec79e 573 ProSitePatterns PS00211 ABC transporters family signature. 503 517 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Astex_0922 84f41795f048ebe1463e6d96f9eec79e 573 Pfam PF00664 ABC transporter transmembrane region 134 281 1.3E-8 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 Astex_0922 84f41795f048ebe1463e6d96f9eec79e 573 SUPERFAMILY SSF52540 360 566 4.35E-43 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0922 84f41795f048ebe1463e6d96f9eec79e 573 SMART SM00382 393 572 8.1E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_0922 84f41795f048ebe1463e6d96f9eec79e 573 Gene3D G3DSA:1.20.1560.10 12 351 2.2E-20 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Astex_0922 84f41795f048ebe1463e6d96f9eec79e 573 SUPERFAMILY SSF90123 35 349 3.79E-25 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Astex_0922 84f41795f048ebe1463e6d96f9eec79e 573 Gene3D G3DSA:3.40.50.300 362 573 3.4E-51 T 13-10-2018 Astex_3619 b1143949a9a335a15cd0afbfccb7a8cc 501 Gene3D G3DSA:3.50.50.60 1 497 1.2E-185 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_3619 b1143949a9a335a15cd0afbfccb7a8cc 501 PIRSF PIRSF011396 1 499 7.7E-188 T 13-10-2018 IPR033856 Flavin-dependent tryptophan halogenase Astex_3619 b1143949a9a335a15cd0afbfccb7a8cc 501 SUPERFAMILY SSF51905 6 421 3.45E-26 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_3619 b1143949a9a335a15cd0afbfccb7a8cc 501 Pfam PF04820 Tryptophan halogenase 8 461 1.6E-179 T 13-10-2018 IPR006905 Flavin-dependent halogenase Astex_0038 ddb61db942529e4ad10e155590c759f0 518 Gene3D G3DSA:1.10.287.130 2 95 1.1E-24 T 13-10-2018 Astex_0038 ddb61db942529e4ad10e155590c759f0 518 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 144 254 1.5E-24 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_0038 ddb61db942529e4ad10e155590c759f0 518 Pfam PF00512 His Kinase A (phospho-acceptor) domain 33 97 2.2E-19 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_0038 ddb61db942529e4ad10e155590c759f0 518 SUPERFAMILY SSF47384 22 98 1.53E-20 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Astex_0038 ddb61db942529e4ad10e155590c759f0 518 SUPERFAMILY SSF52172 395 514 8.4E-38 T 13-10-2018 IPR011006 CheY-like superfamily Astex_0038 ddb61db942529e4ad10e155590c759f0 518 PRINTS PR00344 Bacterial sensor protein C-terminal signature 216 234 9.1E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_0038 ddb61db942529e4ad10e155590c759f0 518 PRINTS PR00344 Bacterial sensor protein C-terminal signature 180 194 9.1E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_0038 ddb61db942529e4ad10e155590c759f0 518 PRINTS PR00344 Bacterial sensor protein C-terminal signature 240 253 9.1E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_0038 ddb61db942529e4ad10e155590c759f0 518 PRINTS PR00344 Bacterial sensor protein C-terminal signature 198 208 9.1E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_0038 ddb61db942529e4ad10e155590c759f0 518 SUPERFAMILY SSF55874 86 254 4.98E-42 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_0038 ddb61db942529e4ad10e155590c759f0 518 Pfam PF00072 Response regulator receiver domain 398 508 1.9E-27 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_0038 ddb61db942529e4ad10e155590c759f0 518 SMART SM00448 396 508 1.1E-38 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_0038 ddb61db942529e4ad10e155590c759f0 518 SMART SM00388 32 97 2.5E-23 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_0038 ddb61db942529e4ad10e155590c759f0 518 Gene3D G3DSA:3.40.50.12740 396 518 1.4E-39 T 13-10-2018 Astex_0038 ddb61db942529e4ad10e155590c759f0 518 Gene3D G3DSA:3.30.565.10 96 258 7.4E-42 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_0038 ddb61db942529e4ad10e155590c759f0 518 SMART SM00387 143 256 1.9E-29 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_3147 a8fbb38cc4101825d50a256b31e2f039 335 Gene3D G3DSA:3.30.2350.10 87 304 1.2E-63 T 13-10-2018 Astex_3147 a8fbb38cc4101825d50a256b31e2f039 335 SUPERFAMILY SSF55174 16 67 3.77E-6 T 13-10-2018 Astex_3147 a8fbb38cc4101825d50a256b31e2f039 335 Gene3D G3DSA:3.10.290.10 6 68 1.6E-10 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 Astex_3147 a8fbb38cc4101825d50a256b31e2f039 335 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 13 308 1.4E-62 T 13-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 Astex_3147 a8fbb38cc4101825d50a256b31e2f039 335 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 141 155 - T 13-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Astex_3147 a8fbb38cc4101825d50a256b31e2f039 335 Pfam PF00849 RNA pseudouridylate synthase 102 255 5.3E-33 T 13-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 Astex_3147 a8fbb38cc4101825d50a256b31e2f039 335 SUPERFAMILY SSF55120 89 318 3.68E-57 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 Astex_0591 6ed19e022394b2479a17fcb16335fafc 93 SUPERFAMILY SSF48295 15 93 9.94E-21 T 13-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 Astex_0591 6ed19e022394b2479a17fcb16335fafc 93 Pfam PF06627 Protein of unknown function (DUF1153) 8 93 6.6E-42 T 13-10-2018 IPR009534 Protein of unknown function DUF1153 Astex_0591 6ed19e022394b2479a17fcb16335fafc 93 Gene3D G3DSA:1.10.10.10 13 93 5.6E-35 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1082 ae24277a4a96b01806891da41d589f1c 222 Pfam PF00226 DnaJ domain 166 217 2.8E-10 T 13-10-2018 IPR001623 DnaJ domain Astex_1082 ae24277a4a96b01806891da41d589f1c 222 Gene3D G3DSA:1.10.287.110 148 220 3.7E-11 T 13-10-2018 IPR036869 Chaperone J-domain superfamily Astex_1082 ae24277a4a96b01806891da41d589f1c 222 SMART SM00271 163 221 1.6E-7 T 13-10-2018 IPR001623 DnaJ domain Astex_1082 ae24277a4a96b01806891da41d589f1c 222 SUPERFAMILY SSF46565 163 217 1.57E-12 T 13-10-2018 IPR036869 Chaperone J-domain superfamily Astex_1082 ae24277a4a96b01806891da41d589f1c 222 PRINTS PR00625 DnaJ domain signature 201 221 4.1E-6 T 13-10-2018 IPR001623 DnaJ domain Astex_1082 ae24277a4a96b01806891da41d589f1c 222 PRINTS PR00625 DnaJ domain signature 184 199 4.1E-6 T 13-10-2018 IPR001623 DnaJ domain Astex_1082 ae24277a4a96b01806891da41d589f1c 222 PRINTS PR00625 DnaJ domain signature 166 184 4.1E-6 T 13-10-2018 IPR001623 DnaJ domain Astex_0086 226eef27b09e67b003b51ef0e50b9062 257 SUPERFAMILY SSF56300 1 247 4.24E-44 T 13-10-2018 Astex_0086 226eef27b09e67b003b51ef0e50b9062 257 Gene3D G3DSA:3.60.21.10 1 256 1.5E-33 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like Astex_0086 226eef27b09e67b003b51ef0e50b9062 257 Pfam PF00149 Calcineurin-like phosphoesterase 1 191 8.4E-18 T 13-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 Astex_2820 f59e67d91b723c7c90a9f47ed4e9e661 555 Gene3D G3DSA:3.60.15.10 11 437 3.4E-151 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Astex_2820 f59e67d91b723c7c90a9f47ed4e9e661 555 SMART SM00849 22 216 2.4E-14 T 13-10-2018 IPR001279 Metallo-beta-lactamase Astex_2820 f59e67d91b723c7c90a9f47ed4e9e661 555 SUPERFAMILY SSF56281 10 423 2.23E-80 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Astex_2820 f59e67d91b723c7c90a9f47ed4e9e661 555 Gene3D G3DSA:3.40.50.10710 208 357 3.4E-151 T 13-10-2018 Astex_2820 f59e67d91b723c7c90a9f47ed4e9e661 555 Pfam PF00753 Metallo-beta-lactamase superfamily 31 176 1.8E-12 T 13-10-2018 IPR001279 Metallo-beta-lactamase Astex_2820 f59e67d91b723c7c90a9f47ed4e9e661 555 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 364 409 1.8E-8 T 13-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain Astex_2820 f59e67d91b723c7c90a9f47ed4e9e661 555 Gene3D G3DSA:3.10.20.580 450 555 8.9E-8 T 13-10-2018 Astex_0766 b8a8f7e8abfd825c3e25ef1f62a4d444 106 Pfam PF11342 Protein of unknown function (DUF3144) 12 88 1.5E-20 T 13-10-2018 IPR021490 Protein of unknown function DUF3144 Astex_0369 7329d2ab29dc46e1081e3eab1f5531c3 1212 SUPERFAMILY SSF56935 44 1210 1.24E-47 T 13-10-2018 Astex_0369 7329d2ab29dc46e1081e3eab1f5531c3 1212 Pfam PF00593 TonB dependent receptor 579 1208 9.3E-14 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_0369 7329d2ab29dc46e1081e3eab1f5531c3 1212 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 45 1210 4.6E-120 T 13-10-2018 IPR010104 Bacterial TonB-dependent receptor Astex_0369 7329d2ab29dc46e1081e3eab1f5531c3 1212 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 53 - T 13-10-2018 IPR010916 TonB box, conserved site Astex_0369 7329d2ab29dc46e1081e3eab1f5531c3 1212 Pfam PF07715 TonB-dependent Receptor Plug Domain 65 178 2.3E-13 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_0369 7329d2ab29dc46e1081e3eab1f5531c3 1212 Gene3D G3DSA:2.170.130.10 35 184 4.0E-17 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_2427 82c73d6e688dfc3a10404cd81b816697 248 Gene3D G3DSA:3.30.450.80 7 174 1.7E-30 T 13-10-2018 IPR036693 Transcription factor LuxR-like, autoinducer-binding domain superfamily Astex_2427 82c73d6e688dfc3a10404cd81b816697 248 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 216 228 1.9E-7 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Astex_2427 82c73d6e688dfc3a10404cd81b816697 248 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 200 1.9E-7 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Astex_2427 82c73d6e688dfc3a10404cd81b816697 248 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 200 216 1.9E-7 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Astex_2427 82c73d6e688dfc3a10404cd81b816697 248 SUPERFAMILY SSF46894 171 246 2.21E-17 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Astex_2427 82c73d6e688dfc3a10404cd81b816697 248 ProSitePatterns PS00622 LuxR-type HTH domain signature. 200 227 - T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Astex_2427 82c73d6e688dfc3a10404cd81b816697 248 Pfam PF00196 Bacterial regulatory proteins, luxR family 185 238 2.1E-16 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Astex_2427 82c73d6e688dfc3a10404cd81b816697 248 SUPERFAMILY SSF75516 9 175 1.18E-30 T 13-10-2018 IPR036693 Transcription factor LuxR-like, autoinducer-binding domain superfamily Astex_2427 82c73d6e688dfc3a10404cd81b816697 248 Pfam PF03472 Autoinducer binding domain 24 166 8.2E-28 T 13-10-2018 IPR005143 Transcription factor LuxR-like, autoinducer-binding domain Astex_2427 82c73d6e688dfc3a10404cd81b816697 248 SMART SM00421 183 240 7.6E-18 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Astex_2427 82c73d6e688dfc3a10404cd81b816697 248 Gene3D G3DSA:1.10.10.10 177 246 1.2E-18 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_2940 529121f55c6a87d36443a0c144797aaf 196 SUPERFAMILY SSF63380 1 92 1.02E-25 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel Astex_2940 529121f55c6a87d36443a0c144797aaf 196 PIRSF PIRSF000498 1 196 6.6E-75 T 13-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Astex_2940 529121f55c6a87d36443a0c144797aaf 196 Gene3D G3DSA:2.40.30.20 1 88 1.0E-25 T 13-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Astex_2940 529121f55c6a87d36443a0c144797aaf 196 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 191 4.4E-61 T 13-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Astex_2940 529121f55c6a87d36443a0c144797aaf 196 Pfam PF00677 Lumazine binding domain 99 183 5.3E-26 T 13-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Astex_2940 529121f55c6a87d36443a0c144797aaf 196 Pfam PF00677 Lumazine binding domain 3 86 3.3E-21 T 13-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Astex_2940 529121f55c6a87d36443a0c144797aaf 196 SUPERFAMILY SSF63380 92 194 6.97E-34 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel Astex_2940 529121f55c6a87d36443a0c144797aaf 196 Gene3D G3DSA:2.40.30.20 101 196 1.6E-35 T 13-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Astex_2338 bbc29d6d7eab9bc37a4de238ed6b24e7 335 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 34 52 - T 13-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 Astex_2338 bbc29d6d7eab9bc37a4de238ed6b24e7 335 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 36 49 - T 13-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 Astex_2338 bbc29d6d7eab9bc37a4de238ed6b24e7 335 Gene3D G3DSA:3.40.50.1100 9 313 3.5E-112 T 13-10-2018 Astex_2338 bbc29d6d7eab9bc37a4de238ed6b24e7 335 SUPERFAMILY SSF53686 4 329 2.88E-93 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme Astex_2338 bbc29d6d7eab9bc37a4de238ed6b24e7 335 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 10 307 8.2E-63 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme Astex_2338 bbc29d6d7eab9bc37a4de238ed6b24e7 335 Gene3D G3DSA:3.40.50.1100 39 152 3.5E-112 T 13-10-2018 Astex_0534 397ba534b173ddf8944feb7589a7f5b7 563 Pfam PF11954 Domain of unknown function (DUF3471) 474 547 5.2E-8 T 13-10-2018 IPR021860 Peptidase S12, Pab87-related, C-terminal Astex_0534 397ba534b173ddf8944feb7589a7f5b7 563 Gene3D G3DSA:3.40.710.10 150 463 1.2E-91 T 13-10-2018 Astex_0534 397ba534b173ddf8944feb7589a7f5b7 563 SUPERFAMILY SSF56601 154 467 4.77E-85 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like Astex_0534 397ba534b173ddf8944feb7589a7f5b7 563 Pfam PF00144 Beta-lactamase 166 451 3.3E-66 T 13-10-2018 IPR001466 Beta-lactamase-related Astex_3648 614eca1d9a402186c1882eb5f31513d7 272 Gene3D G3DSA:1.10.3720.10 68 263 4.0E-19 T 13-10-2018 IPR035906 MetI-like superfamily Astex_3648 614eca1d9a402186c1882eb5f31513d7 272 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 261 1.3E-17 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Astex_3648 614eca1d9a402186c1882eb5f31513d7 272 SUPERFAMILY SSF161098 73 256 1.7E-27 T 13-10-2018 IPR035906 MetI-like superfamily Astex_1977 a194077e80bdfeae07f73bbf72b41402 339 SMART SM00354 5 75 4.1E-18 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Astex_1977 a194077e80bdfeae07f73bbf72b41402 339 Gene3D G3DSA:3.40.50.2300 60 314 1.3E-63 T 13-10-2018 Astex_1977 a194077e80bdfeae07f73bbf72b41402 339 SUPERFAMILY SSF47413 4 62 2.49E-16 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Astex_1977 a194077e80bdfeae07f73bbf72b41402 339 Gene3D G3DSA:1.10.260.40 2 59 1.6E-19 T 13-10-2018 Astex_1977 a194077e80bdfeae07f73bbf72b41402 339 Gene3D G3DSA:3.40.50.2300 169 299 1.3E-63 T 13-10-2018 Astex_1977 a194077e80bdfeae07f73bbf72b41402 339 Pfam PF00356 Bacterial regulatory proteins, lacI family 10 50 1.2E-14 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Astex_1977 a194077e80bdfeae07f73bbf72b41402 339 SUPERFAMILY SSF53822 77 338 3.03E-57 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Astex_1977 a194077e80bdfeae07f73bbf72b41402 339 Pfam PF13377 Periplasmic binding protein-like domain 177 337 5.8E-36 T 13-10-2018 Astex_0173 cffd09518b58ea38315e2d384949149b 237 SUPERFAMILY SSF53335 62 216 3.57E-27 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Astex_0173 cffd09518b58ea38315e2d384949149b 237 Pfam PF02390 Putative methyltransferase 63 219 1.5E-43 T 13-10-2018 Astex_0173 cffd09518b58ea38315e2d384949149b 237 Gene3D G3DSA:3.40.50.150 48 235 1.0E-52 T 13-10-2018 Astex_0173 cffd09518b58ea38315e2d384949149b 237 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 20 235 26.873 T 13-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 Astex_0173 cffd09518b58ea38315e2d384949149b 237 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 62 219 4.9E-40 T 13-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 Astex_2515 d3e1ee2ff7927a9f36bd5e3713b37bc0 619 Gene3D G3DSA:1.50.10.10 244 614 4.2E-68 T 13-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 Astex_2515 d3e1ee2ff7927a9f36bd5e3713b37bc0 619 Pfam PF00723 Glycosyl hydrolases family 15 246 562 2.1E-22 T 13-10-2018 IPR011613 GH15-like domain Reactome: R-HSA-70221 Astex_2515 d3e1ee2ff7927a9f36bd5e3713b37bc0 619 SUPERFAMILY SSF48208 228 615 1.29E-78 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 Astex_1508 9201770885398be8b701cef9a5c8be37 107 Hamap MF_00010 UPF0060 membrane protein YnfA [ynfA]. 1 106 21.615 T 13-10-2018 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 Astex_1508 9201770885398be8b701cef9a5c8be37 107 SUPERFAMILY SSF103481 7 106 1.26E-8 T 13-10-2018 Astex_1508 9201770885398be8b701cef9a5c8be37 107 Pfam PF02694 Uncharacterised BCR, YnfA/UPF0060 family 1 107 2.1E-25 T 13-10-2018 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 Astex_0717 1427c38f89928973119810265e3b1df4 621 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 615 44.701 T 13-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Astex_0717 1427c38f89928973119810265e3b1df4 621 Gene3D G3DSA:3.50.30.80 426 577 5.1E-54 T 13-10-2018 Astex_0717 1427c38f89928973119810265e3b1df4 621 Pfam PF00920 Dehydratase family 34 612 4.4E-220 T 13-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Astex_0717 1427c38f89928973119810265e3b1df4 621 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 514 525 - T 13-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Astex_0717 1427c38f89928973119810265e3b1df4 621 SUPERFAMILY SSF52016 426 616 5.89E-60 T 13-10-2018 Astex_0717 1427c38f89928973119810265e3b1df4 621 SUPERFAMILY SSF143975 4 425 1.11E-134 T 13-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Astex_0717 1427c38f89928973119810265e3b1df4 621 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 13-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Astex_0717 1427c38f89928973119810265e3b1df4 621 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 615 8.5E-250 T 13-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Astex_0618 7c04fe17847212ad7ea50a5c316ad370 328 TIGRFAM TIGR01139 cysK: cysteine synthase A 26 325 6.9E-131 T 13-10-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 Astex_0618 7c04fe17847212ad7ea50a5c316ad370 328 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 27 313 3.5E-65 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme Astex_0618 7c04fe17847212ad7ea50a5c316ad370 328 SUPERFAMILY SSF53686 21 326 5.5E-97 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme Astex_0618 7c04fe17847212ad7ea50a5c316ad370 328 Gene3D G3DSA:3.40.50.1100 65 164 3.5E-118 T 13-10-2018 Astex_0618 7c04fe17847212ad7ea50a5c316ad370 328 Gene3D G3DSA:3.40.50.1100 24 321 3.5E-118 T 13-10-2018 Astex_0618 7c04fe17847212ad7ea50a5c316ad370 328 TIGRFAM TIGR01136 cysKM: cysteine synthase 26 325 6.8E-127 T 13-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 Astex_0208 a11f777dcabf7af0cc11a86afe384183 143 SUPERFAMILY SSF81343 10 136 2.03E-26 T 13-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Astex_0208 a11f777dcabf7af0cc11a86afe384183 143 ProSitePatterns PS01000 Succinate dehydrogenase cytochrome b subunit signature 1. 12 36 - T 13-10-2018 IPR018495 Succinate dehydrogenase, cytochrome b subunit, conserved site GO:0000104|GO:0006099|GO:0009055|GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Astex_0208 a11f777dcabf7af0cc11a86afe384183 143 PIRSF PIRSF000178 5 136 7.6E-30 T 13-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Astex_0208 a11f777dcabf7af0cc11a86afe384183 143 ProSitePatterns PS01001 Succinate dehydrogenase cytochrome b subunit signature 2. 92 105 - T 13-10-2018 IPR018495 Succinate dehydrogenase, cytochrome b subunit, conserved site GO:0000104|GO:0006099|GO:0009055|GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Astex_0208 a11f777dcabf7af0cc11a86afe384183 143 Gene3D G3DSA:1.20.1300.10 6 136 1.7E-31 T 13-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Astex_0208 a11f777dcabf7af0cc11a86afe384183 143 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 11 133 2.3E-28 T 13-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Astex_0208 a11f777dcabf7af0cc11a86afe384183 143 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 10 130 7.0E-24 T 13-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Astex_2403 d26d9c203f60e7c07f98fe9b03571c0b 435 ProSitePatterns PS00216 Sugar transport proteins signature 1. 74 89 - T 13-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Astex_2403 d26d9c203f60e7c07f98fe9b03571c0b 435 SUPERFAMILY SSF103473 5 430 7.19E-72 T 13-10-2018 IPR036259 MFS transporter superfamily Astex_2403 d26d9c203f60e7c07f98fe9b03571c0b 435 Pfam PF07690 Major Facilitator Superfamily 30 271 1.8E-31 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Astex_2403 d26d9c203f60e7c07f98fe9b03571c0b 435 Gene3D G3DSA:1.20.1250.20 14 429 2.7E-62 T 13-10-2018 Astex_0185 a49d5250b71840a3b4d73d82a1ad4ae7 317 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 10 219 1.5E-68 T 13-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 Astex_0185 a49d5250b71840a3b4d73d82a1ad4ae7 317 SUPERFAMILY SSF55120 10 239 2.1E-73 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 Astex_0185 a49d5250b71840a3b4d73d82a1ad4ae7 317 Gene3D G3DSA:3.30.2350.10 2 243 6.4E-82 T 13-10-2018 Astex_0185 a49d5250b71840a3b4d73d82a1ad4ae7 317 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 181 239 5.4E-9 T 13-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 Astex_0185 a49d5250b71840a3b4d73d82a1ad4ae7 317 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 10 315 18.357 T 13-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 Astex_0185 a49d5250b71840a3b4d73d82a1ad4ae7 317 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 32 180 3.1E-53 T 13-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 Astex_3623 eed52da2d844d0cdc4686616e07efc45 892 Pfam PF00593 TonB dependent receptor 405 891 1.3E-32 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_3623 eed52da2d844d0cdc4686616e07efc45 892 Gene3D G3DSA:2.40.170.20 227 892 2.3E-40 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_3623 eed52da2d844d0cdc4686616e07efc45 892 SUPERFAMILY SSF56935 27 891 8.06E-79 T 13-10-2018 Astex_3623 eed52da2d844d0cdc4686616e07efc45 892 Pfam PF07715 TonB-dependent Receptor Plug Domain 62 158 6.1E-14 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_3623 eed52da2d844d0cdc4686616e07efc45 892 Gene3D G3DSA:2.170.130.10 38 161 3.5E-16 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_3623 eed52da2d844d0cdc4686616e07efc45 892 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 36 891 4.3E-189 T 13-10-2018 IPR010104 Bacterial TonB-dependent receptor Astex_3709 38c099b352d81fdd26f598a726863c94 158 Pfam PF05593 RHS Repeat 30 62 1.5E-5 T 13-10-2018 IPR031325 RHS repeat Astex_2418 77447537dbc87572c975c6634d784c16 452 SMART SM00283 192 446 1.3E-43 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_2418 77447537dbc87572c975c6634d784c16 452 Gene3D G3DSA:1.10.287.950 170 452 4.3E-51 T 13-10-2018 Astex_2418 77447537dbc87572c975c6634d784c16 452 SUPERFAMILY SSF58104 169 445 1.74E-57 T 13-10-2018 Astex_2418 77447537dbc87572c975c6634d784c16 452 Gene3D G3DSA:1.10.490.10 6 169 4.2E-43 T 13-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 Astex_2418 77447537dbc87572c975c6634d784c16 452 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 319 348 2.8E-9 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_2418 77447537dbc87572c975c6634d784c16 452 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 220 249 2.8E-9 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_2418 77447537dbc87572c975c6634d784c16 452 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 367 396 2.8E-9 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_2418 77447537dbc87572c975c6634d784c16 452 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 256 418 5.9E-30 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_2418 77447537dbc87572c975c6634d784c16 452 SUPERFAMILY SSF46458 7 160 1.06E-29 T 13-10-2018 IPR009050 Globin-like superfamily Astex_2418 77447537dbc87572c975c6634d784c16 452 Pfam PF11563 Protoglobin 7 168 3.8E-36 T 13-10-2018 Astex_1069 a0c1a3fcf25152a15abf126bffe38be5 107 PRINTS PR00355 Adrenodoxin signature 61 75 4.8E-7 T 13-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 Astex_1069 a0c1a3fcf25152a15abf126bffe38be5 107 PRINTS PR00355 Adrenodoxin signature 84 92 4.8E-7 T 13-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 Astex_1069 a0c1a3fcf25152a15abf126bffe38be5 107 PRINTS PR00355 Adrenodoxin signature 42 52 4.8E-7 T 13-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 Astex_1069 a0c1a3fcf25152a15abf126bffe38be5 107 SUPERFAMILY SSF54292 7 103 1.34E-25 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 Astex_1069 a0c1a3fcf25152a15abf126bffe38be5 107 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 13 92 4.3E-14 T 13-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 Astex_1069 a0c1a3fcf25152a15abf126bffe38be5 107 Gene3D G3DSA:3.10.20.30 1 107 6.5E-31 T 13-10-2018 IPR012675 Beta-grasp domain superfamily Astex_0972 5789ff02eb08989d6dfedf55e0b4e2ee 410 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 34 352 1.6E-79 T 13-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 Astex_0972 5789ff02eb08989d6dfedf55e0b4e2ee 410 Gene3D G3DSA:3.30.1360.180 249 349 6.6E-124 T 13-10-2018 Astex_0972 5789ff02eb08989d6dfedf55e0b4e2ee 410 SUPERFAMILY SSF53649 26 390 5.72E-90 T 13-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 Astex_0972 5789ff02eb08989d6dfedf55e0b4e2ee 410 Gene3D G3DSA:3.40.720.10 34 400 6.6E-124 T 13-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 Astex_2776 09e5b08014e5054bc1ce7e0481c52a7f 479 TIGRFAM TIGR00836 amt: ammonium transporter 77 477 8.4E-124 T 13-10-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 Astex_2776 09e5b08014e5054bc1ce7e0481c52a7f 479 Gene3D G3DSA:1.10.3430.10 50 479 5.2E-129 T 13-10-2018 IPR029020 Ammonium/urea transporter Astex_2776 09e5b08014e5054bc1ce7e0481c52a7f 479 SUPERFAMILY SSF111352 74 460 5.36E-117 T 13-10-2018 Astex_2776 09e5b08014e5054bc1ce7e0481c52a7f 479 ProSitePatterns PS01219 Ammonium transporters signature. 241 266 - T 13-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 Astex_2776 09e5b08014e5054bc1ce7e0481c52a7f 479 Pfam PF00909 Ammonium Transporter Family 78 477 2.2E-108 T 13-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 Astex_0359 7a543cdde878e41cf01c33f8cf19b827 512 SUPERFAMILY SSF53167 25 512 3.59E-145 T 13-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 Astex_0359 7a543cdde878e41cf01c33f8cf19b827 512 Pfam PF10423 Bacterial AMP nucleoside phosphorylase N-terminus 28 191 2.6E-46 T 13-10-2018 IPR018953 AMP nucleoside phosphorylase, N-terminal KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 Astex_0359 7a543cdde878e41cf01c33f8cf19b827 512 Gene3D G3DSA:3.40.50.1580 201 512 2.0E-106 T 13-10-2018 Astex_0359 7a543cdde878e41cf01c33f8cf19b827 512 Hamap MF_01932 AMP nucleosidase [amn]. 19 512 55.189 T 13-10-2018 IPR011271 AMP nucleosidase GO:0008714|GO:0009116|GO:0044209 KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 Astex_0359 7a543cdde878e41cf01c33f8cf19b827 512 TIGRFAM TIGR01717 AMP-nucleosdse: AMP nucleosidase 27 512 1.3E-199 T 13-10-2018 IPR011271 AMP nucleosidase GO:0008714|GO:0009116|GO:0044209 KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 Astex_0359 7a543cdde878e41cf01c33f8cf19b827 512 Pfam PF01048 Phosphorylase superfamily 297 458 1.5E-18 T 13-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 Astex_0359 7a543cdde878e41cf01c33f8cf19b827 512 Gene3D G3DSA:3.30.1730.10 18 200 5.8E-43 T 13-10-2018 IPR037109 AMP nucleoside phosphorylase, N-terminal domain superfamily KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 Astex_3017 84034b493212b4cd593b43318a6a62bc 742 Pfam PF13089 Polyphosphate kinase N-terminal domain 40 144 1.7E-37 T 13-10-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 Astex_3017 84034b493212b4cd593b43318a6a62bc 742 Hamap MF_00347 Polyphosphate kinase [ppk]. 37 721 28.13 T 13-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 Astex_3017 84034b493212b4cd593b43318a6a62bc 742 SUPERFAMILY SSF56024 349 528 2.17E-57 T 13-10-2018 Astex_3017 84034b493212b4cd593b43318a6a62bc 742 SUPERFAMILY SSF56024 533 717 2.11E-67 T 13-10-2018 Astex_3017 84034b493212b4cd593b43318a6a62bc 742 PIRSF PIRSF015589 18 731 3.5E-275 T 13-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 Astex_3017 84034b493212b4cd593b43318a6a62bc 742 Gene3D G3DSA:3.30.870.10 533 718 8.6E-66 T 13-10-2018 Astex_3017 84034b493212b4cd593b43318a6a62bc 742 Gene3D G3DSA:3.30.1840.10 34 345 6.0E-98 T 13-10-2018 IPR036830 Polyphosphate kinase middle domain superfamily KEGG: 00190+2.7.4.1 Astex_3017 84034b493212b4cd593b43318a6a62bc 742 SUPERFAMILY SSF140356 38 140 2.22E-37 T 13-10-2018 IPR036832 Polyphosphate kinase N-terminal domain superfamily KEGG: 00190+2.7.4.1 Astex_3017 84034b493212b4cd593b43318a6a62bc 742 Pfam PF13090 Polyphosphate kinase C-terminal domain 363 716 2.2E-155 T 13-10-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 Astex_3017 84034b493212b4cd593b43318a6a62bc 742 Pfam PF02503 Polyphosphate kinase middle domain 155 353 6.4E-58 T 13-10-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 Astex_3017 84034b493212b4cd593b43318a6a62bc 742 Gene3D G3DSA:3.30.870.10 354 532 2.5E-74 T 13-10-2018 Astex_3017 84034b493212b4cd593b43318a6a62bc 742 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 40 718 7.5E-288 T 13-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 Astex_3017 84034b493212b4cd593b43318a6a62bc 742 SUPERFAMILY SSF143724 143 345 3.92E-58 T 13-10-2018 Astex_0718 ee7db2a2c287b2fffeb6d93a52487e65 238 Pfam PF13852 Protein of unknown function (DUF4197) 39 238 5.6E-63 T 13-10-2018 IPR025245 Protein of unknown function DUF4197 Astex_0141 1bf95142ccfc9e99e098e16806ec0ad9 446 Pfam PF10396 GTP-binding protein TrmE N-terminus 7 119 4.4E-36 T 13-10-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 Astex_0141 1bf95142ccfc9e99e098e16806ec0ad9 446 Gene3D G3DSA:3.40.50.300 216 376 1.6E-99 T 13-10-2018 Astex_0141 1bf95142ccfc9e99e098e16806ec0ad9 446 Pfam PF12631 MnmE helical domain 122 443 3.0E-49 T 13-10-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 Astex_0141 1bf95142ccfc9e99e098e16806ec0ad9 446 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 6 446 30.857 T 13-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 Astex_0141 1bf95142ccfc9e99e098e16806ec0ad9 446 Gene3D G3DSA:3.30.1360.120 1 120 6.8E-42 T 13-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 Astex_0141 1bf95142ccfc9e99e098e16806ec0ad9 446 SUPERFAMILY SSF116878 120 446 1.28E-43 T 13-10-2018 Astex_0141 1bf95142ccfc9e99e098e16806ec0ad9 446 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 216 363 2.5E-17 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Astex_0141 1bf95142ccfc9e99e098e16806ec0ad9 446 Gene3D G3DSA:1.20.120.430 121 446 1.6E-99 T 13-10-2018 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 Astex_0141 1bf95142ccfc9e99e098e16806ec0ad9 446 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 14 446 1.1E-83 T 13-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 Astex_0141 1bf95142ccfc9e99e098e16806ec0ad9 446 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 218 238 3.1E-5 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Astex_0141 1bf95142ccfc9e99e098e16806ec0ad9 446 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 279 294 3.1E-5 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Astex_0141 1bf95142ccfc9e99e098e16806ec0ad9 446 SUPERFAMILY SSF52540 72 365 2.97E-38 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0141 1bf95142ccfc9e99e098e16806ec0ad9 446 Pfam PF01926 50S ribosome-binding GTPase 217 311 1.9E-19 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Astex_0003 b5bb9b54bef3538f75d498ed4339413a 374 SMART SM00382 24 366 0.0033 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_0003 b5bb9b54bef3538f75d498ed4339413a 374 ProSitePatterns PS00618 RecF protein signature 2. 313 331 - T 13-10-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 Astex_0003 b5bb9b54bef3538f75d498ed4339413a 374 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 374 74.755 T 13-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 Astex_0003 b5bb9b54bef3538f75d498ed4339413a 374 Gene3D G3DSA:1.20.1050.90 128 312 3.1E-68 T 13-10-2018 Astex_0003 b5bb9b54bef3538f75d498ed4339413a 374 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 5 349 5.7E-48 T 13-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 Astex_0003 b5bb9b54bef3538f75d498ed4339413a 374 Gene3D G3DSA:3.40.50.300 8 348 3.1E-68 T 13-10-2018 Astex_0003 b5bb9b54bef3538f75d498ed4339413a 374 SUPERFAMILY SSF52540 4 366 2.01E-34 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0003 b5bb9b54bef3538f75d498ed4339413a 374 Pfam PF02463 RecF/RecN/SMC N terminal domain 5 333 2.9E-15 T 13-10-2018 IPR003395 RecF/RecN/SMC, N-terminal Astex_3490 2466bcd881bef845fc08c252d4904814 781 SUPERFAMILY SSF50249 236 642 1.39E-127 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Astex_3490 2466bcd881bef845fc08c252d4904814 781 TIGRFAM TIGR02063 RNase_R: ribonuclease R 17 724 1.8E-203 T 13-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 Astex_3490 2466bcd881bef845fc08c252d4904814 781 Hamap MF_01895 Ribonuclease R [rnr]. 31 726 51.474 T 13-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 Astex_3490 2466bcd881bef845fc08c252d4904814 781 Gene3D G3DSA:2.40.50.140 647 737 8.2E-12 T 13-10-2018 Astex_3490 2466bcd881bef845fc08c252d4904814 781 SMART SM00316 643 726 1.6E-5 T 13-10-2018 IPR022967 RNA-binding domain, S1 Astex_3490 2466bcd881bef845fc08c252d4904814 781 ProSitePatterns PS01175 Ribonuclease II family signature. 564 588 - T 13-10-2018 IPR022966 Ribonuclease II/R, conserved site Astex_3490 2466bcd881bef845fc08c252d4904814 781 Pfam PF00773 RNB domain 266 596 2.1E-92 T 13-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 Astex_3490 2466bcd881bef845fc08c252d4904814 781 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 128 713 1.3E-137 T 13-10-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 Astex_3490 2466bcd881bef845fc08c252d4904814 781 Pfam PF00575 S1 RNA binding domain 642 693 3.2E-7 T 13-10-2018 IPR003029 S1 domain GO:0003676 Astex_3490 2466bcd881bef845fc08c252d4904814 781 SMART SM00955 266 597 5.4E-151 T 13-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 Astex_3490 2466bcd881bef845fc08c252d4904814 781 SUPERFAMILY SSF50249 643 724 1.54E-17 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Astex_1842 2de6e3bd07632ed18c3400c400c4abec 462 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 5 461 29.148 T 13-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Astex_1842 2de6e3bd07632ed18c3400c400c4abec 462 Pfam PF02875 Mur ligase family, glutamate ligase domain 333 402 4.2E-8 T 13-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Astex_1842 2de6e3bd07632ed18c3400c400c4abec 462 SUPERFAMILY SSF53244 327 454 1.05E-27 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Astex_1842 2de6e3bd07632ed18c3400c400c4abec 462 Gene3D G3DSA:3.40.1390.10 5 84 3.9E-20 T 13-10-2018 Astex_1842 2de6e3bd07632ed18c3400c400c4abec 462 SUPERFAMILY SSF53623 108 316 1.57E-43 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Astex_1842 2de6e3bd07632ed18c3400c400c4abec 462 Pfam PF01225 Mur ligase family, catalytic domain 30 76 1.8E-7 T 13-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 Astex_1842 2de6e3bd07632ed18c3400c400c4abec 462 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 35 458 2.0E-97 T 13-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Astex_1842 2de6e3bd07632ed18c3400c400c4abec 462 SUPERFAMILY SSF63418 6 100 6.8E-20 T 13-10-2018 IPR035911 MurE/MurF, N-terminal Astex_1842 2de6e3bd07632ed18c3400c400c4abec 462 Pfam PF08245 Mur ligase middle domain 109 298 2.1E-39 T 13-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Astex_1842 2de6e3bd07632ed18c3400c400c4abec 462 Gene3D G3DSA:3.90.190.20 314 461 9.9E-29 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Astex_1842 2de6e3bd07632ed18c3400c400c4abec 462 Gene3D G3DSA:3.40.1190.10 85 313 2.7E-49 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Astex_0046 952ce6a17e22af5929e2e341b9e9cf55 380 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 10 338 8.9E-82 T 13-10-2018 IPR004559 Oxygen-independent coproporphyrinogen III oxidase-like GO:0004109|GO:0005737|GO:0006779|GO:0055114 Astex_0046 952ce6a17e22af5929e2e341b9e9cf55 380 Pfam PF04055 Radical SAM superfamily 14 183 7.7E-16 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Astex_0046 952ce6a17e22af5929e2e341b9e9cf55 380 SUPERFAMILY SSF102114 6 379 6.15E-93 T 13-10-2018 Astex_0046 952ce6a17e22af5929e2e341b9e9cf55 380 SMART SM00729 8 229 1.4E-45 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Astex_0046 952ce6a17e22af5929e2e341b9e9cf55 380 Gene3D G3DSA:3.80.30.20 1 311 1.9E-89 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe Astex_0046 952ce6a17e22af5929e2e341b9e9cf55 380 Pfam PF06969 HemN C-terminal domain 312 368 1.2E-8 T 13-10-2018 IPR010723 HemN, C-terminal Astex_0401 23aef23f564fbcd6b4f9122f7d8aff0d 210 SUPERFAMILY SSF55729 35 189 2.16E-26 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Astex_0401 23aef23f564fbcd6b4f9122f7d8aff0d 210 Pfam PF13302 Acetyltransferase (GNAT) domain 39 183 1.6E-20 T 13-10-2018 IPR000182 GNAT domain Astex_0401 23aef23f564fbcd6b4f9122f7d8aff0d 210 Gene3D G3DSA:3.40.630.30 30 207 2.1E-29 T 13-10-2018 Astex_3527 78459f309a97fad1e208fd2f6e2880b8 314 Gene3D G3DSA:3.50.50.60 5 309 2.5E-92 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_3527 78459f309a97fad1e208fd2f6e2880b8 314 PRINTS PR00419 Adrenodoxin reductase family signature 27 40 5.2E-6 T 13-10-2018 Astex_3527 78459f309a97fad1e208fd2f6e2880b8 314 PRINTS PR00419 Adrenodoxin reductase family signature 4 26 5.2E-6 T 13-10-2018 Astex_3527 78459f309a97fad1e208fd2f6e2880b8 314 Gene3D G3DSA:3.90.660.10 43 274 2.5E-92 T 13-10-2018 Astex_3527 78459f309a97fad1e208fd2f6e2880b8 314 SUPERFAMILY SSF51905 1 313 1.62E-26 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_3527 78459f309a97fad1e208fd2f6e2880b8 314 Pfam PF13450 NAD(P)-binding Rossmann-like domain 7 64 4.5E-16 T 13-10-2018 Astex_1236 48238288a559db9f8957badf9e64b73a 416 SUPERFAMILY SSF53850 41 281 4.71E-25 T 13-10-2018 Astex_1236 48238288a559db9f8957badf9e64b73a 416 Gene3D G3DSA:3.40.190.10 41 398 4.5E-128 T 13-10-2018 Astex_1236 48238288a559db9f8957badf9e64b73a 416 Pfam PF13379 NMT1-like family 34 287 1.8E-94 T 13-10-2018 Astex_1236 48238288a559db9f8957badf9e64b73a 416 Gene3D G3DSA:3.40.190.10 131 403 4.5E-128 T 13-10-2018 Astex_0223 c667ab95fa06c2425ed51e20fb9494ea 416 Pfam PF06850 PHB de-polymerase C-terminus 211 411 2.2E-96 T 13-10-2018 IPR009656 PHB de-polymerase, C-terminal Astex_0223 c667ab95fa06c2425ed51e20fb9494ea 416 TIGRFAM TIGR01849 PHB_depoly_PhaZ: polyhydroxyalkanoate depolymerase, intracellular 2 411 2.0E-186 T 13-10-2018 IPR010915 Polyhydroxyalkanoate depolymerase Astex_0223 c667ab95fa06c2425ed51e20fb9494ea 416 SUPERFAMILY SSF53474 104 409 3.93E-34 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_0223 c667ab95fa06c2425ed51e20fb9494ea 416 PIRSF PIRSF020818 1 416 2.6E-182 T 13-10-2018 IPR010915 Polyhydroxyalkanoate depolymerase Astex_0404 6f61b027cd830602fe79c246dc66d574 385 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 12 187 6.6E-57 T 13-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain Astex_0404 6f61b027cd830602fe79c246dc66d574 385 Gene3D G3DSA:3.40.50.300 8 207 4.9E-72 T 13-10-2018 Astex_0404 6f61b027cd830602fe79c246dc66d574 385 SUPERFAMILY SSF90002 289 383 1.96E-25 T 13-10-2018 Astex_0404 6f61b027cd830602fe79c246dc66d574 385 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 289 383 6.5E-23 T 13-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal Astex_0404 6f61b027cd830602fe79c246dc66d574 385 SMART SM00833 289 383 2.4E-13 T 13-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal Astex_0404 6f61b027cd830602fe79c246dc66d574 385 Gene3D G3DSA:3.30.1220.10 269 383 4.5E-36 T 13-10-2018 IPR036627 CobW-like, C-terminal domain superfamily Astex_0404 6f61b027cd830602fe79c246dc66d574 385 SUPERFAMILY SSF52540 10 208 5.25E-41 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2425 10c3da6902443f67a53346a089db7532 296 Pfam PF12833 Helix-turn-helix domain 209 288 9.7E-14 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Astex_2425 10c3da6902443f67a53346a089db7532 296 SMART SM00342 202 287 4.6E-9 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Astex_2425 10c3da6902443f67a53346a089db7532 296 Gene3D G3DSA:1.10.10.60 183 293 7.5E-18 T 13-10-2018 Astex_2425 10c3da6902443f67a53346a089db7532 296 SUPERFAMILY SSF46689 238 288 5.38E-7 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Astex_1951 6875cb3ba1f63ff3457e203acfd44aa7 338 Pfam PF02685 Glucokinase 21 332 4.6E-87 T 13-10-2018 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0005536|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 Astex_1951 6875cb3ba1f63ff3457e203acfd44aa7 338 Gene3D G3DSA:3.40.367.20 119 317 1.6E-88 T 13-10-2018 Astex_1951 6875cb3ba1f63ff3457e203acfd44aa7 338 Gene3D G3DSA:3.30.420.40 21 328 1.6E-88 T 13-10-2018 Astex_1951 6875cb3ba1f63ff3457e203acfd44aa7 338 SUPERFAMILY SSF53067 21 330 1.24E-48 T 13-10-2018 Astex_0828 b7684b3b24b27de8890a2dd9081983c1 500 PRINTS PR00145 Argininosuccinate lyase family signature 170 192 7.0E-6 T 13-10-2018 Astex_0828 b7684b3b24b27de8890a2dd9081983c1 500 PRINTS PR00145 Argininosuccinate lyase family signature 354 370 7.0E-6 T 13-10-2018 Astex_0828 b7684b3b24b27de8890a2dd9081983c1 500 PRINTS PR00145 Argininosuccinate lyase family signature 212 232 7.0E-6 T 13-10-2018 Astex_0828 b7684b3b24b27de8890a2dd9081983c1 500 Gene3D G3DSA:1.10.40.30 445 499 3.0E-24 T 13-10-2018 Astex_0828 b7684b3b24b27de8890a2dd9081983c1 500 Pfam PF10415 Fumarase C C-terminus 445 497 9.9E-21 T 13-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 Astex_0828 b7684b3b24b27de8890a2dd9081983c1 500 ProSitePatterns PS00163 Fumarate lyases signature. 354 363 - T 13-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 Astex_0828 b7684b3b24b27de8890a2dd9081983c1 500 Hamap MF_00743 Fumarate hydratase class II [fumC]. 41 499 91.35 T 13-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 Astex_0828 b7684b3b24b27de8890a2dd9081983c1 500 TIGRFAM TIGR00979 fumC_II: fumarate hydratase, class II 42 498 1.6E-228 T 13-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 Astex_0828 b7684b3b24b27de8890a2dd9081983c1 500 Gene3D G3DSA:1.20.200.10 176 443 7.9E-122 T 13-10-2018 Astex_0828 b7684b3b24b27de8890a2dd9081983c1 500 SUPERFAMILY SSF48557 41 499 2.51E-153 T 13-10-2018 IPR008948 L-Aspartase-like GO:0003824 Astex_0828 b7684b3b24b27de8890a2dd9081983c1 500 PRINTS PR00149 Fumarate lyase superfamily signature 217 235 2.8E-33 T 13-10-2018 IPR000362 Fumarate lyase family Astex_0828 b7684b3b24b27de8890a2dd9081983c1 500 PRINTS PR00149 Fumarate lyase superfamily signature 308 335 2.8E-33 T 13-10-2018 IPR000362 Fumarate lyase family Astex_0828 b7684b3b24b27de8890a2dd9081983c1 500 PRINTS PR00149 Fumarate lyase superfamily signature 354 370 2.8E-33 T 13-10-2018 IPR000362 Fumarate lyase family Astex_0828 b7684b3b24b27de8890a2dd9081983c1 500 PRINTS PR00149 Fumarate lyase superfamily signature 171 189 2.8E-33 T 13-10-2018 IPR000362 Fumarate lyase family Astex_0828 b7684b3b24b27de8890a2dd9081983c1 500 Gene3D G3DSA:1.10.275.10 42 175 4.1E-58 T 13-10-2018 IPR024083 Fumarase/histidase, N-terminal Astex_0828 b7684b3b24b27de8890a2dd9081983c1 500 Pfam PF00206 Lyase 49 379 2.3E-114 T 13-10-2018 IPR022761 Fumarate lyase, N-terminal Astex_0058 f84d37c166db2de57b83fb52cadca6b6 250 PIRSF PIRSF000161 2 250 5.4E-64 T 13-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Astex_0058 f84d37c166db2de57b83fb52cadca6b6 250 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 4 107 8.7E-13 T 13-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Astex_0058 f84d37c166db2de57b83fb52cadca6b6 250 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 110 247 1.8E-41 T 13-10-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Astex_0058 f84d37c166db2de57b83fb52cadca6b6 250 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 43 248 2.8E-56 T 13-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Astex_0058 f84d37c166db2de57b83fb52cadca6b6 250 SUPERFAMILY SSF55347 109 219 2.62E-33 T 13-10-2018 Astex_0058 f84d37c166db2de57b83fb52cadca6b6 250 Gene3D G3DSA:3.30.360.10 108 217 1.1E-62 T 13-10-2018 Astex_0058 f84d37c166db2de57b83fb52cadca6b6 250 SUPERFAMILY SSF51735 4 248 8.47E-30 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_0058 f84d37c166db2de57b83fb52cadca6b6 250 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 4 248 31.267 T 13-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Astex_0058 f84d37c166db2de57b83fb52cadca6b6 250 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 133 150 - T 13-10-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Astex_0058 f84d37c166db2de57b83fb52cadca6b6 250 Gene3D G3DSA:3.40.50.720 7 236 1.1E-62 T 13-10-2018 Astex_3377 1c6c496c6e58faaf04613ff587fd7a48 396 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 44 378 1.9E-89 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 Astex_3377 1c6c496c6e58faaf04613ff587fd7a48 396 Gene3D G3DSA:2.40.50.100 68 212 3.1E-108 T 13-10-2018 Astex_3377 1c6c496c6e58faaf04613ff587fd7a48 396 Gene3D G3DSA:1.10.287.470 103 176 3.1E-108 T 13-10-2018 Astex_3377 1c6c496c6e58faaf04613ff587fd7a48 396 Gene3D G3DSA:2.40.30.170 55 306 3.1E-108 T 13-10-2018 Astex_3377 1c6c496c6e58faaf04613ff587fd7a48 396 Gene3D G3DSA:2.40.420.20 307 376 3.1E-108 T 13-10-2018 Astex_3377 1c6c496c6e58faaf04613ff587fd7a48 396 SUPERFAMILY SSF111369 56 302 6.54E-81 T 13-10-2018 Astex_3377 1c6c496c6e58faaf04613ff587fd7a48 396 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 69 296 1.4E-15 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain Astex_1066 73512fbab9423aa80ce3a9c7a7c25d59 171 Pfam PF04542 Sigma-70 region 2 20 87 2.9E-16 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 Astex_1066 73512fbab9423aa80ce3a9c7a7c25d59 171 Gene3D G3DSA:1.10.1740.10 2 87 3.2E-20 T 13-10-2018 Astex_1066 73512fbab9423aa80ce3a9c7a7c25d59 171 Gene3D G3DSA:1.10.10.10 89 170 3.1E-15 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1066 73512fbab9423aa80ce3a9c7a7c25d59 171 Pfam PF08281 Sigma-70, region 4 112 163 1.9E-12 T 13-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Astex_1066 73512fbab9423aa80ce3a9c7a7c25d59 171 SUPERFAMILY SSF88659 106 167 2.83E-13 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Astex_1066 73512fbab9423aa80ce3a9c7a7c25d59 171 SUPERFAMILY SSF88946 6 92 1.57E-22 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 Astex_1066 73512fbab9423aa80ce3a9c7a7c25d59 171 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 16 164 4.6E-20 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 Astex_1843 08870ff5146d5347c2c3fe93a0b52a2e 487 SUPERFAMILY SSF63418 14 93 7.72E-21 T 13-10-2018 IPR035911 MurE/MurF, N-terminal Astex_1843 08870ff5146d5347c2c3fe93a0b52a2e 487 Gene3D G3DSA:3.40.1390.10 5 94 4.5E-20 T 13-10-2018 Astex_1843 08870ff5146d5347c2c3fe93a0b52a2e 487 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 4 485 32.646 T 13-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 Astex_1843 08870ff5146d5347c2c3fe93a0b52a2e 487 Gene3D G3DSA:3.90.190.20 337 487 1.8E-57 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Astex_1843 08870ff5146d5347c2c3fe93a0b52a2e 487 Gene3D G3DSA:3.40.1190.10 95 333 9.7E-62 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Astex_1843 08870ff5146d5347c2c3fe93a0b52a2e 487 SUPERFAMILY SSF53244 331 485 5.49E-48 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Astex_1843 08870ff5146d5347c2c3fe93a0b52a2e 487 Pfam PF08245 Mur ligase middle domain 102 309 2.0E-45 T 13-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Astex_1843 08870ff5146d5347c2c3fe93a0b52a2e 487 SUPERFAMILY SSF53623 95 329 3.66E-64 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Astex_1843 08870ff5146d5347c2c3fe93a0b52a2e 487 Pfam PF02875 Mur ligase family, glutamate ligase domain 331 415 1.6E-23 T 13-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Astex_1843 08870ff5146d5347c2c3fe93a0b52a2e 487 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 19 485 2.2E-139 T 13-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 Astex_1843 08870ff5146d5347c2c3fe93a0b52a2e 487 Pfam PF01225 Mur ligase family, catalytic domain 20 67 3.9E-10 T 13-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 Astex_1851 acca424e35eea38c41eff3400828c1ed 245 Gene3D G3DSA:3.40.80.10 1 154 6.9E-47 T 13-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 Astex_1851 acca424e35eea38c41eff3400828c1ed 245 SUPERFAMILY SSF55846 5 157 1.13E-51 T 13-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 Astex_1851 acca424e35eea38c41eff3400828c1ed 245 SUPERFAMILY SSF47090 177 238 3.14E-13 T 13-10-2018 IPR036365 PGBD-like superfamily Astex_1851 acca424e35eea38c41eff3400828c1ed 245 SMART SM00644 6 141 6.7E-37 T 13-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 Astex_1851 acca424e35eea38c41eff3400828c1ed 245 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 15 141 2.5E-31 T 13-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 Astex_1851 acca424e35eea38c41eff3400828c1ed 245 Gene3D G3DSA:1.10.101.10 165 237 1.1E-12 T 13-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 Astex_1851 acca424e35eea38c41eff3400828c1ed 245 Pfam PF01471 Putative peptidoglycan binding domain 178 231 2.2E-5 T 13-10-2018 IPR002477 Peptidoglycan binding-like Astex_2743 dacaf0f14c2e4c08769bf5327c684745 100 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 43 95 4.0E-18 T 13-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Astex_2743 dacaf0f14c2e4c08769bf5327c684745 100 Hamap MF_00422 Protein translocase subunit SecE [secE]. 39 94 11.031 T 13-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 Astex_2743 dacaf0f14c2e4c08769bf5327c684745 100 Gene3D G3DSA:1.20.5.1030 39 95 5.6E-14 T 13-10-2018 IPR038379 SecE superfamily Astex_2743 dacaf0f14c2e4c08769bf5327c684745 100 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 42 95 3.4E-16 T 13-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 Astex_0941 b2900b9b2dc3fea239e18d903edf44e3 396 Gene3D G3DSA:2.40.30.10 340 395 8.3E-27 T 13-10-2018 Astex_0941 b2900b9b2dc3fea239e18d903edf44e3 396 SUPERFAMILY SSF50465 304 396 3.17E-34 T 13-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal Astex_0941 b2900b9b2dc3fea239e18d903edf44e3 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 395 2.0E-225 T 13-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 Astex_0941 b2900b9b2dc3fea239e18d903edf44e3 396 Gene3D G3DSA:2.40.30.10 209 336 4.6E-53 T 13-10-2018 Astex_0941 b2900b9b2dc3fea239e18d903edf44e3 396 SUPERFAMILY SSF52540 3 216 1.89E-61 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0941 b2900b9b2dc3fea239e18d903edf44e3 396 SUPERFAMILY SSF50447 207 303 3.53E-31 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Astex_0941 b2900b9b2dc3fea239e18d903edf44e3 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 2.3E-59 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Astex_0941 b2900b9b2dc3fea239e18d903edf44e3 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 59.56 T 13-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 Astex_0941 b2900b9b2dc3fea239e18d903edf44e3 396 Gene3D G3DSA:3.40.50.300 1 205 8.1E-71 T 13-10-2018 Astex_0941 b2900b9b2dc3fea239e18d903edf44e3 396 PRINTS PR00315 GTP-binding elongation factor signature 94 105 7.2E-25 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Astex_0941 b2900b9b2dc3fea239e18d903edf44e3 396 PRINTS PR00315 GTP-binding elongation factor signature 131 140 7.2E-25 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Astex_0941 b2900b9b2dc3fea239e18d903edf44e3 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 7.2E-25 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Astex_0941 b2900b9b2dc3fea239e18d903edf44e3 396 PRINTS PR00315 GTP-binding elongation factor signature 58 66 7.2E-25 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Astex_0941 b2900b9b2dc3fea239e18d903edf44e3 396 PRINTS PR00315 GTP-binding elongation factor signature 78 88 7.2E-25 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Astex_0941 b2900b9b2dc3fea239e18d903edf44e3 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site Astex_0941 b2900b9b2dc3fea239e18d903edf44e3 396 Pfam PF03144 Elongation factor Tu domain 2 227 296 1.1E-17 T 13-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 Astex_0941 b2900b9b2dc3fea239e18d903edf44e3 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 14 148 1.3E-15 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Astex_0941 b2900b9b2dc3fea239e18d903edf44e3 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 9.4E-33 T 13-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal Astex_1334 f23d92d6eac8dda4e7dd04edce56ebc2 98 Pfam PF05101 Type IV secretory pathway, VirB3-like protein 11 92 1.4E-27 T 13-10-2018 IPR007792 Type IV secretion system, VirB3 / TrbD / AvhB Astex_0813 2cb0d0fcfd6474d4a1ad5957242a8d63 273 SUPERFAMILY SSF51366 1 272 2.69E-67 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Astex_0813 2cb0d0fcfd6474d4a1ad5957242a8d63 273 Pfam PF00977 Histidine biosynthesis protein 5 255 5.2E-70 T 13-10-2018 IPR006062 Histidine biosynthesis GO:0000105 Astex_0813 2cb0d0fcfd6474d4a1ad5957242a8d63 273 Gene3D G3DSA:3.20.20.70 1 273 1.4E-86 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_0813 2cb0d0fcfd6474d4a1ad5957242a8d63 273 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 272 9.8E-96 T 13-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 Astex_0813 2cb0d0fcfd6474d4a1ad5957242a8d63 273 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 272 41.731 T 13-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 Astex_2030 af1db2149d897fd5f90cd282f8fdbf12 574 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 524 553 - T 13-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 Astex_2030 af1db2149d897fd5f90cd282f8fdbf12 574 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 292 299 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Astex_2030 af1db2149d897fd5f90cd282f8fdbf12 574 SUPERFAMILY SSF56059 84 354 8.31E-69 T 13-10-2018 Astex_2030 af1db2149d897fd5f90cd282f8fdbf12 574 Gene3D G3DSA:2.40.50.100 499 572 1.5E-18 T 13-10-2018 Astex_2030 af1db2149d897fd5f90cd282f8fdbf12 574 SUPERFAMILY SSF52440 1 114 6.4E-51 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily Astex_2030 af1db2149d897fd5f90cd282f8fdbf12 574 Pfam PF02785 Biotin carboxylase C-terminal domain 342 446 1.4E-36 T 13-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Astex_2030 af1db2149d897fd5f90cd282f8fdbf12 574 SMART SM00878 342 446 6.9E-58 T 13-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Astex_2030 af1db2149d897fd5f90cd282f8fdbf12 574 Gene3D G3DSA:3.30.470.130 1 453 4.1E-197 T 13-10-2018 Astex_2030 af1db2149d897fd5f90cd282f8fdbf12 574 SUPERFAMILY SSF51246 337 452 1.67E-39 T 13-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 Astex_2030 af1db2149d897fd5f90cd282f8fdbf12 574 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 118 328 5.1E-74 T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Astex_2030 af1db2149d897fd5f90cd282f8fdbf12 574 Pfam PF00364 Biotin-requiring enzyme 507 570 1.4E-13 T 13-10-2018 IPR000089 Biotin/lipoyl attachment Astex_2030 af1db2149d897fd5f90cd282f8fdbf12 574 SUPERFAMILY SSF51230 500 572 1.26E-17 T 13-10-2018 IPR011053 Single hybrid motif Astex_2030 af1db2149d897fd5f90cd282f8fdbf12 574 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 111 6.5E-47 T 13-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Astex_0508 8ec77f774dfe5ae472867441439f6ca2 595 Gene3D G3DSA:1.10.510.10 358 528 5.0E-44 T 13-10-2018 Astex_0508 8ec77f774dfe5ae472867441439f6ca2 595 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 394 406 - T 13-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 Astex_0508 8ec77f774dfe5ae472867441439f6ca2 595 Gene3D G3DSA:3.30.200.20 263 357 5.0E-44 T 13-10-2018 Astex_0508 8ec77f774dfe5ae472867441439f6ca2 595 Pfam PF00069 Protein kinase domain 275 475 1.1E-28 T 13-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Astex_0508 8ec77f774dfe5ae472867441439f6ca2 595 SMART SM00332 3 235 9.5E-18 T 13-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Astex_0508 8ec77f774dfe5ae472867441439f6ca2 595 Gene3D G3DSA:3.60.40.10 3 238 7.5E-49 T 13-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Astex_0508 8ec77f774dfe5ae472867441439f6ca2 595 SUPERFAMILY SSF81606 13 237 4.97E-48 T 13-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Astex_0508 8ec77f774dfe5ae472867441439f6ca2 595 SMART SM00220 270 527 2.4E-18 T 13-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Astex_0508 8ec77f774dfe5ae472867441439f6ca2 595 SUPERFAMILY SSF56112 260 524 6.47E-45 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily Astex_0508 8ec77f774dfe5ae472867441439f6ca2 595 Pfam PF13672 Protein phosphatase 2C 17 209 2.8E-17 T 13-10-2018 Astex_0508 8ec77f774dfe5ae472867441439f6ca2 595 SMART SM00331 24 237 5.1E-12 T 13-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Astex_2883 48b9e923bf29f6a7c8f396ee27830374 444 SUPERFAMILY SSF55073 291 431 2.75E-12 T 13-10-2018 IPR029787 Nucleotide cyclase Astex_2883 48b9e923bf29f6a7c8f396ee27830374 444 SUPERFAMILY SSF52172 150 280 6.22E-5 T 13-10-2018 IPR011006 CheY-like superfamily Astex_2883 48b9e923bf29f6a7c8f396ee27830374 444 Gene3D G3DSA:3.30.70.270 286 435 6.9E-18 T 13-10-2018 Astex_2883 48b9e923bf29f6a7c8f396ee27830374 444 SUPERFAMILY SSF52172 5 90 1.42E-5 T 13-10-2018 IPR011006 CheY-like superfamily Astex_2883 48b9e923bf29f6a7c8f396ee27830374 444 SMART SM00267 274 444 1.6E-5 T 13-10-2018 IPR000160 GGDEF domain Astex_2883 48b9e923bf29f6a7c8f396ee27830374 444 Pfam PF00990 Diguanylate cyclase, GGDEF domain 286 432 3.5E-12 T 13-10-2018 IPR000160 GGDEF domain Astex_2883 48b9e923bf29f6a7c8f396ee27830374 444 Gene3D G3DSA:3.40.50.12740 13 282 2.3E-8 T 13-10-2018 Astex_1207 91a33311884f42cc1b3c0ed9d5ca45c9 213 Gene3D G3DSA:3.40.50.12140 9 213 2.8E-46 T 13-10-2018 Astex_1207 91a33311884f42cc1b3c0ed9d5ca45c9 213 Pfam PF13709 Domain of unknown function (DUF4159) 15 211 8.2E-54 T 13-10-2018 IPR025297 Domain of unknown function DUF4159 Astex_0524 35a8568a8abde4abd743ffd1e5dd5035 344 Gene3D G3DSA:3.40.50.10610 156 287 9.0E-21 T 13-10-2018 Astex_0524 35a8568a8abde4abd743ffd1e5dd5035 344 Pfam PF03783 Curli production assembly/transport component CsgG 75 279 1.5E-17 T 13-10-2018 IPR005534 Curli production assembly/transport component CsgG GO:0030288 Astex_0400 c994cb7fac5f961373ec4d7e10c4c41e 350 Hamap MF_01454 GTPase Obg [obg]. 2 329 46.096 T 13-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 Astex_0400 c994cb7fac5f961373ec4d7e10c4c41e 350 Pfam PF01926 50S ribosome-binding GTPase 162 281 4.9E-23 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Astex_0400 c994cb7fac5f961373ec4d7e10c4c41e 350 SUPERFAMILY SSF52540 162 331 4.28E-45 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0400 c994cb7fac5f961373ec4d7e10c4c41e 350 PIRSF PIRSF002401 1 345 9.1E-131 T 13-10-2018 IPR035101 GTP-binding protein, Obg-type Astex_0400 c994cb7fac5f961373ec4d7e10c4c41e 350 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 3 323 8.6E-138 T 13-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 Astex_0400 c994cb7fac5f961373ec4d7e10c4c41e 350 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 211 226 3.5E-34 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Astex_0400 c994cb7fac5f961373ec4d7e10c4c41e 350 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 228 246 3.5E-34 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Astex_0400 c994cb7fac5f961373ec4d7e10c4c41e 350 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 3.5E-34 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Astex_0400 c994cb7fac5f961373ec4d7e10c4c41e 350 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 3.5E-34 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Astex_0400 c994cb7fac5f961373ec4d7e10c4c41e 350 ProSitePatterns PS00905 GTP1/OBG family signature. 213 226 - T 13-10-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 Astex_0400 c994cb7fac5f961373ec4d7e10c4c41e 350 SUPERFAMILY SSF82051 2 158 1.7E-54 T 13-10-2018 IPR036726 GTP1/OBG domain superfamily Astex_0400 c994cb7fac5f961373ec4d7e10c4c41e 350 Pfam PF01018 GTP1/OBG 5 158 5.9E-58 T 13-10-2018 IPR006169 GTP1/OBG domain Astex_0400 c994cb7fac5f961373ec4d7e10c4c41e 350 Gene3D G3DSA:2.70.210.12 1 158 3.3E-58 T 13-10-2018 IPR036726 GTP1/OBG domain superfamily Astex_0400 c994cb7fac5f961373ec4d7e10c4c41e 350 Gene3D G3DSA:3.40.50.300 160 343 1.3E-47 T 13-10-2018 Astex_3447 9562ab22a92fe663330481ef2ae53f80 227 Gene3D G3DSA:1.10.357.10 22 194 1.2E-35 T 13-10-2018 Astex_3447 9562ab22a92fe663330481ef2ae53f80 227 SUPERFAMILY SSF48498 106 224 2.86E-11 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily Astex_3447 9562ab22a92fe663330481ef2ae53f80 227 Pfam PF00440 Bacterial regulatory proteins, tetR family 39 85 8.7E-17 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Astex_3447 9562ab22a92fe663330481ef2ae53f80 227 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 52 4.6E-8 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Astex_3447 9562ab22a92fe663330481ef2ae53f80 227 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 60 83 4.6E-8 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Astex_3447 9562ab22a92fe663330481ef2ae53f80 227 SUPERFAMILY SSF46689 28 94 1.4E-18 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Astex_0056 6056405d8aa4bb3cefea65b98f035979 632 SUPERFAMILY SSF53067 4 184 8.03E-67 T 13-10-2018 Astex_0056 6056405d8aa4bb3cefea65b98f035979 632 Gene3D G3DSA:3.30.420.40 180 361 3.1E-162 T 13-10-2018 Astex_0056 6056405d8aa4bb3cefea65b98f035979 632 SUPERFAMILY SSF100934 529 602 9.42E-6 T 13-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 Astex_0056 6056405d8aa4bb3cefea65b98f035979 632 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 332 346 - T 13-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 Astex_0056 6056405d8aa4bb3cefea65b98f035979 632 Gene3D G3DSA:2.60.34.10 378 518 8.6E-66 T 13-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 Astex_0056 6056405d8aa4bb3cefea65b98f035979 632 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 13-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 Astex_0056 6056405d8aa4bb3cefea65b98f035979 632 Gene3D G3DSA:3.90.640.10 224 311 3.1E-162 T 13-10-2018 Astex_0056 6056405d8aa4bb3cefea65b98f035979 632 Gene3D G3DSA:1.20.1270.10 519 602 4.6E-28 T 13-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 Astex_0056 6056405d8aa4bb3cefea65b98f035979 632 PRINTS PR00301 70kDa heat shock protein signature 138 158 2.8E-79 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Astex_0056 6056405d8aa4bb3cefea65b98f035979 632 PRINTS PR00301 70kDa heat shock protein signature 360 380 2.8E-79 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Astex_0056 6056405d8aa4bb3cefea65b98f035979 632 PRINTS PR00301 70kDa heat shock protein signature 383 402 2.8E-79 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Astex_0056 6056405d8aa4bb3cefea65b98f035979 632 PRINTS PR00301 70kDa heat shock protein signature 3 16 2.8E-79 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Astex_0056 6056405d8aa4bb3cefea65b98f035979 632 PRINTS PR00301 70kDa heat shock protein signature 329 345 2.8E-79 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Astex_0056 6056405d8aa4bb3cefea65b98f035979 632 PRINTS PR00301 70kDa heat shock protein signature 31 43 2.8E-79 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Astex_0056 6056405d8aa4bb3cefea65b98f035979 632 PRINTS PR00301 70kDa heat shock protein signature 464 480 2.8E-79 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Astex_0056 6056405d8aa4bb3cefea65b98f035979 632 PRINTS PR00301 70kDa heat shock protein signature 54 62 2.8E-79 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Astex_0056 6056405d8aa4bb3cefea65b98f035979 632 PRINTS PR00301 70kDa heat shock protein signature 197 207 2.8E-79 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Astex_0056 6056405d8aa4bb3cefea65b98f035979 632 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 191 204 - T 13-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 Astex_0056 6056405d8aa4bb3cefea65b98f035979 632 Pfam PF00012 Hsp70 protein 4 598 1.2E-274 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Astex_0056 6056405d8aa4bb3cefea65b98f035979 632 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 624 37.256 T 13-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 Astex_0056 6056405d8aa4bb3cefea65b98f035979 632 SUPERFAMILY SSF53067 186 377 2.33E-67 T 13-10-2018 Astex_0056 6056405d8aa4bb3cefea65b98f035979 632 SUPERFAMILY SSF100920 379 535 3.53E-62 T 13-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 Astex_0056 6056405d8aa4bb3cefea65b98f035979 632 Gene3D G3DSA:3.30.420.40 5 374 3.1E-162 T 13-10-2018 Astex_0056 6056405d8aa4bb3cefea65b98f035979 632 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 598 4.1E-293 T 13-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 Astex_3164 2a4a837b9f0488b72549a34cbaf84447 356 Pfam PF11776 Nickel/cobalt transporter regulator 302 350 7.7E-13 T 13-10-2018 IPR024572 Nickel/cobalt homeostasis protein RcnB Astex_2967 d4488465a42313247d94f399e9021790 119 Gene3D G3DSA:3.90.940.10 1 107 2.7E-24 T 13-10-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 Astex_2967 d4488465a42313247d94f399e9021790 119 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 58 8.3E-19 T 13-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Astex_2967 d4488465a42313247d94f399e9021790 119 Pfam PF01192 RNA polymerase Rpb6 8 60 1.2E-14 T 13-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 Astex_2967 d4488465a42313247d94f399e9021790 119 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 61 16.665 T 13-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Astex_2967 d4488465a42313247d94f399e9021790 119 SUPERFAMILY SSF63562 1 81 1.83E-21 T 13-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 Astex_2967 d4488465a42313247d94f399e9021790 119 SMART SM01409 8 60 1.2E-15 T 13-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 Astex_3787 e5c99c358e66aa703733dbf103b525e3 268 SUPERFAMILY SSF52833 137 264 2.75E-23 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Astex_3787 e5c99c358e66aa703733dbf103b525e3 268 Pfam PF13098 Thioredoxin-like domain 146 259 1.1E-12 T 13-10-2018 IPR012336 Thioredoxin-like fold Astex_3787 e5c99c358e66aa703733dbf103b525e3 268 SUPERFAMILY SSF54423 39 92 2.94E-8 T 13-10-2018 IPR009094 Disulphide bond isomerase DsbC/G, N-terminal domain superfamily GO:0042597 Astex_3787 e5c99c358e66aa703733dbf103b525e3 268 Pfam PF10411 Disulfide bond isomerase protein N-terminus 37 90 1.5E-15 T 13-10-2018 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal Astex_3787 e5c99c358e66aa703733dbf103b525e3 268 Gene3D G3DSA:3.40.30.10 108 265 2.4E-27 T 13-10-2018 Astex_3787 e5c99c358e66aa703733dbf103b525e3 268 Gene3D G3DSA:3.10.450.70 31 93 1.1E-5 T 13-10-2018 IPR009094 Disulphide bond isomerase DsbC/G, N-terminal domain superfamily GO:0042597 Astex_0852 a4eded0daad50a0e124f76e00642d4ed 249 TIGRFAM TIGR02490 flgF: flagellar basal-body rod protein FlgF 6 224 1.5E-56 T 13-10-2018 IPR012836 Flagellar basal-body rod FlgF GO:0030694|GO:0071973 Astex_0852 a4eded0daad50a0e124f76e00642d4ed 249 Pfam PF00460 Flagella basal body rod protein 6 35 4.7E-9 T 13-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 Astex_0852 a4eded0daad50a0e124f76e00642d4ed 249 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 125 6.7E-31 T 13-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G Astex_0852 a4eded0daad50a0e124f76e00642d4ed 249 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 173 242 1.2E-15 T 13-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain Astex_0852 a4eded0daad50a0e124f76e00642d4ed 249 SUPERFAMILY SSF117143 81 206 1.31E-22 T 13-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like Astex_0852 a4eded0daad50a0e124f76e00642d4ed 249 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 13-10-2018 IPR019776 Flagellar basal body rod protein, conserved site Astex_0919 12494e1930eb82332c277cf1ed14d0f7 417 SUPERFAMILY SSF141571 149 239 5.1E-19 T 13-10-2018 Astex_0919 12494e1930eb82332c277cf1ed14d0f7 417 SUPERFAMILY SSF141571 284 403 4.97E-28 T 13-10-2018 Astex_0919 12494e1930eb82332c277cf1ed14d0f7 417 Gene3D G3DSA:2.160.20.80 11 128 2.5E-20 T 13-10-2018 Astex_0919 12494e1930eb82332c277cf1ed14d0f7 417 Pfam PF00805 Pentapeptide repeats (8 copies) 37 72 7.7E-4 T 13-10-2018 IPR001646 Pentapeptide repeat Astex_0919 12494e1930eb82332c277cf1ed14d0f7 417 Pfam PF00805 Pentapeptide repeats (8 copies) 361 398 2.9E-9 T 13-10-2018 IPR001646 Pentapeptide repeat Astex_0919 12494e1930eb82332c277cf1ed14d0f7 417 Pfam PF00805 Pentapeptide repeats (8 copies) 88 121 5.8E-8 T 13-10-2018 IPR001646 Pentapeptide repeat Astex_0919 12494e1930eb82332c277cf1ed14d0f7 417 Pfam PF00805 Pentapeptide repeats (8 copies) 179 215 9.0E-10 T 13-10-2018 IPR001646 Pentapeptide repeat Astex_0919 12494e1930eb82332c277cf1ed14d0f7 417 Pfam PF00805 Pentapeptide repeats (8 copies) 311 347 1.9E-11 T 13-10-2018 IPR001646 Pentapeptide repeat Astex_0919 12494e1930eb82332c277cf1ed14d0f7 417 Gene3D G3DSA:2.160.20.100 356 412 6.1E-10 T 13-10-2018 Astex_0919 12494e1930eb82332c277cf1ed14d0f7 417 Gene3D G3DSA:2.160.20.100 259 355 3.2E-18 T 13-10-2018 Astex_0919 12494e1930eb82332c277cf1ed14d0f7 417 Gene3D G3DSA:2.160.20.80 138 258 5.4E-21 T 13-10-2018 Astex_0919 12494e1930eb82332c277cf1ed14d0f7 417 SUPERFAMILY SSF141571 38 122 1.83E-18 T 13-10-2018 Astex_2816 b7089a1438e6c0b650a8e791eaddb341 500 Pfam PF01059 NADH-ubiquinone oxidoreductase chain 4, amino terminus 47 131 2.0E-6 T 13-10-2018 IPR000260 NADH:ubiquinone oxidoreductase chain 4, N-terminal GO:0006120|GO:0055114 KEGG: 00190+1.6.5.3|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-5083|MetaCyc: PWY-6692|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2816 b7089a1438e6c0b650a8e791eaddb341 500 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 9 492 4.7E-186 T 13-10-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2816 b7089a1438e6c0b650a8e791eaddb341 500 Pfam PF00361 Proton-conducting membrane transporter 139 426 4.9E-87 T 13-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2816 b7089a1438e6c0b650a8e791eaddb341 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 175 199 2.2E-48 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2816 b7089a1438e6c0b650a8e791eaddb341 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 332 351 2.2E-48 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2816 b7089a1438e6c0b650a8e791eaddb341 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 384 410 2.2E-48 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2816 b7089a1438e6c0b650a8e791eaddb341 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 145 164 2.2E-48 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2816 b7089a1438e6c0b650a8e791eaddb341 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 244 268 2.2E-48 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_0837 cebafaf665d625e78854f20115d767b1 243 SUPERFAMILY SSF53448 3 218 6.0E-37 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_0837 cebafaf665d625e78854f20115d767b1 243 Gene3D G3DSA:3.90.550.10 2 199 1.5E-36 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_0837 cebafaf665d625e78854f20115d767b1 243 Pfam PF00535 Glycosyl transferase family 2 6 170 1.7E-25 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 Astex_2242 bbdb3fbfd83df3342ee1af896bf1b9a2 807 SUPERFAMILY SSF52540 387 746 2.59E-38 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2242 bbdb3fbfd83df3342ee1af896bf1b9a2 807 Pfam PF03135 CagE, TrbE, VirB family, component of type IV transporter system 175 379 2.2E-31 T 13-10-2018 IPR018145 CagE, TrbE, VirB component of type IV transporter system, central domain GO:0005524 Astex_2242 bbdb3fbfd83df3342ee1af896bf1b9a2 807 TIGRFAM TIGR00929 VirB4_CagE: type IV secretion/conjugal transfer ATPase, VirB4 family 16 797 1.8E-205 T 13-10-2018 IPR004346 CagE, TrbE, VirB component of type IV transporter system GO:0005524 Astex_0196 f263e7095bdd0f3a6181b1a0a1e031c4 696 Gene3D G3DSA:3.40.710.10 262 602 5.8E-56 T 13-10-2018 Astex_0196 f263e7095bdd0f3a6181b1a0a1e031c4 696 Pfam PF00905 Penicillin binding protein transpeptidase domain 334 426 1.3E-10 T 13-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 Astex_0196 f263e7095bdd0f3a6181b1a0a1e031c4 696 SUPERFAMILY SSF53955 45 256 8.72E-59 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily Astex_0196 f263e7095bdd0f3a6181b1a0a1e031c4 696 Pfam PF06832 Penicillin-Binding Protein C-terminus Family 600 686 7.8E-14 T 13-10-2018 IPR009647 Penicillin-binding, C-terminal KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Astex_0196 f263e7095bdd0f3a6181b1a0a1e031c4 696 Gene3D G3DSA:1.10.3810.10 57 251 7.5E-52 T 13-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Astex_0196 f263e7095bdd0f3a6181b1a0a1e031c4 696 Pfam PF00912 Transglycosylase 65 228 1.4E-43 T 13-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Astex_0196 f263e7095bdd0f3a6181b1a0a1e031c4 696 SUPERFAMILY SSF56601 210 594 7.51E-76 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like Astex_0196 f263e7095bdd0f3a6181b1a0a1e031c4 696 TIGRFAM TIGR02073 PBP_1c: penicillin-binding protein 1C 36 587 6.8E-209 T 13-10-2018 IPR011815 Penicillin-binding protein 1C GO:0008955|GO:0009252 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Astex_1227 ec6976ef173315a924fdb5f180d86844 967 SMART SM00965 53 104 3.3E-8 T 13-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 Astex_1227 ec6976ef173315a924fdb5f180d86844 967 Pfam PF07660 Secretin and TonB N terminus short domain 54 103 8.0E-7 T 13-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 Astex_1227 ec6976ef173315a924fdb5f180d86844 967 Pfam PF07715 TonB-dependent Receptor Plug Domain 144 247 3.0E-10 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_1227 ec6976ef173315a924fdb5f180d86844 967 Pfam PF00593 TonB dependent receptor 499 966 1.8E-28 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_1227 ec6976ef173315a924fdb5f180d86844 967 SUPERFAMILY SSF56935 126 967 4.4E-74 T 13-10-2018 Astex_1227 ec6976ef173315a924fdb5f180d86844 967 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 126 967 1.8E-165 T 13-10-2018 IPR010104 Bacterial TonB-dependent receptor Astex_1227 ec6976ef173315a924fdb5f180d86844 967 Gene3D G3DSA:3.55.50.30 24 132 1.4E-20 T 13-10-2018 Astex_1227 ec6976ef173315a924fdb5f180d86844 967 Gene3D G3DSA:2.40.170.20 251 967 3.7E-34 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_1227 ec6976ef173315a924fdb5f180d86844 967 Gene3D G3DSA:2.170.130.10 133 250 3.3E-11 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_2870 894d7e5e7ab65076d5cdb604f97374a0 467 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 356 365 - T 13-10-2018 IPR025944 Sigma-54 interaction domain, conserved site Astex_2870 894d7e5e7ab65076d5cdb604f97374a0 467 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 229 244 - T 13-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 Astex_2870 894d7e5e7ab65076d5cdb604f97374a0 467 Gene3D G3DSA:3.40.50.300 138 314 3.0E-44 T 13-10-2018 Astex_2870 894d7e5e7ab65076d5cdb604f97374a0 467 SUPERFAMILY SSF46689 356 456 8.06E-11 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Astex_2870 894d7e5e7ab65076d5cdb604f97374a0 467 Gene3D G3DSA:1.10.8.60 315 393 2.1E-21 T 13-10-2018 Astex_2870 894d7e5e7ab65076d5cdb604f97374a0 467 Gene3D G3DSA:1.10.10.60 407 458 6.4E-13 T 13-10-2018 Astex_2870 894d7e5e7ab65076d5cdb604f97374a0 467 SMART SM00382 166 306 1.2E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_2870 894d7e5e7ab65076d5cdb604f97374a0 467 Pfam PF00158 Sigma-54 interaction domain 146 309 7.9E-47 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 Astex_2870 894d7e5e7ab65076d5cdb604f97374a0 467 SUPERFAMILY SSF52172 6 190 1.11E-43 T 13-10-2018 IPR011006 CheY-like superfamily Astex_2870 894d7e5e7ab65076d5cdb604f97374a0 467 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 437 457 7.4E-5 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Astex_2870 894d7e5e7ab65076d5cdb604f97374a0 467 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 420 437 7.4E-5 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Astex_2870 894d7e5e7ab65076d5cdb604f97374a0 467 Pfam PF02954 Bacterial regulatory protein, Fis family 414 452 1.1E-8 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Astex_2870 894d7e5e7ab65076d5cdb604f97374a0 467 Gene3D G3DSA:3.40.50.2300 5 137 9.1E-40 T 13-10-2018 Astex_2870 894d7e5e7ab65076d5cdb604f97374a0 467 SUPERFAMILY SSF52540 146 377 1.87E-54 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2870 894d7e5e7ab65076d5cdb604f97374a0 467 SMART SM00448 7 120 1.1E-31 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_2870 894d7e5e7ab65076d5cdb604f97374a0 467 Pfam PF00072 Response regulator receiver domain 9 120 6.8E-29 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1027 d118a13474597ac0e54964523b1f12af 512 PRINTS PR00344 Bacterial sensor protein C-terminal signature 295 309 8.6E-18 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1027 d118a13474597ac0e54964523b1f12af 512 PRINTS PR00344 Bacterial sensor protein C-terminal signature 354 367 8.6E-18 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1027 d118a13474597ac0e54964523b1f12af 512 PRINTS PR00344 Bacterial sensor protein C-terminal signature 330 348 8.6E-18 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1027 d118a13474597ac0e54964523b1f12af 512 PRINTS PR00344 Bacterial sensor protein C-terminal signature 313 323 8.6E-18 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1027 d118a13474597ac0e54964523b1f12af 512 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 254 369 5.9E-29 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_1027 d118a13474597ac0e54964523b1f12af 512 Gene3D G3DSA:3.30.565.10 208 372 1.7E-49 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_1027 d118a13474597ac0e54964523b1f12af 512 Pfam PF00512 His Kinase A (phospho-acceptor) domain 142 207 2.4E-19 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_1027 d118a13474597ac0e54964523b1f12af 512 Gene3D G3DSA:3.30.450.20 22 132 1.5E-29 T 13-10-2018 Astex_1027 d118a13474597ac0e54964523b1f12af 512 Pfam PF00989 PAS fold 16 125 4.6E-16 T 13-10-2018 IPR013767 PAS fold GO:0006355 Astex_1027 d118a13474597ac0e54964523b1f12af 512 Pfam PF00072 Response regulator receiver domain 391 505 1.4E-26 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1027 d118a13474597ac0e54964523b1f12af 512 SMART SM00448 389 505 5.1E-35 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1027 d118a13474597ac0e54964523b1f12af 512 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 14 135 1.8E-24 T 13-10-2018 IPR000014 PAS domain Astex_1027 d118a13474597ac0e54964523b1f12af 512 SMART SM00086 86 128 0.0021 T 13-10-2018 IPR001610 PAC motif Astex_1027 d118a13474597ac0e54964523b1f12af 512 SMART SM00387 254 370 2.3E-39 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_1027 d118a13474597ac0e54964523b1f12af 512 SUPERFAMILY SSF52172 388 509 9.96E-36 T 13-10-2018 IPR011006 CheY-like superfamily Astex_1027 d118a13474597ac0e54964523b1f12af 512 SUPERFAMILY SSF47384 133 207 8.83E-20 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Astex_1027 d118a13474597ac0e54964523b1f12af 512 Gene3D G3DSA:3.40.50.12740 388 512 6.9E-39 T 13-10-2018 Astex_1027 d118a13474597ac0e54964523b1f12af 512 SUPERFAMILY SSF55785 25 137 2.09E-25 T 13-10-2018 IPR035965 PAS domain superfamily Astex_1027 d118a13474597ac0e54964523b1f12af 512 Gene3D G3DSA:1.10.287.130 133 207 2.5E-24 T 13-10-2018 Astex_1027 d118a13474597ac0e54964523b1f12af 512 SUPERFAMILY SSF55874 196 371 1.57E-45 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_1027 d118a13474597ac0e54964523b1f12af 512 SMART SM00388 141 207 6.5E-21 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_1027 d118a13474597ac0e54964523b1f12af 512 SMART SM00091 14 82 4.9E-9 T 13-10-2018 IPR000014 PAS domain Astex_2753 38c9c42454af37b4892f8a1aef500435 379 Pfam PF01551 Peptidase family M23 272 366 5.1E-31 T 13-10-2018 IPR016047 Peptidase M23 Astex_2753 38c9c42454af37b4892f8a1aef500435 379 SUPERFAMILY SSF51261 240 369 1.83E-54 T 13-10-2018 IPR011055 Duplicated hybrid motif Astex_2753 38c9c42454af37b4892f8a1aef500435 379 Gene3D G3DSA:2.70.70.10 221 374 3.0E-47 T 13-10-2018 IPR011055 Duplicated hybrid motif Astex_2419 e96a3cb101db0873f950baf7a00e7201 258 SUPERFAMILY SSF52172 4 126 4.41E-17 T 13-10-2018 IPR011006 CheY-like superfamily Astex_2419 e96a3cb101db0873f950baf7a00e7201 258 Gene3D G3DSA:3.40.50.2300 3 130 2.8E-16 T 13-10-2018 Astex_2419 e96a3cb101db0873f950baf7a00e7201 258 SMART SM00448 3 120 0.0062 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_2419 e96a3cb101db0873f950baf7a00e7201 258 SMART SM00448 134 246 1.1E-16 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_2419 e96a3cb101db0873f950baf7a00e7201 258 SUPERFAMILY SSF52172 134 251 2.99E-30 T 13-10-2018 IPR011006 CheY-like superfamily Astex_2419 e96a3cb101db0873f950baf7a00e7201 258 Pfam PF00072 Response regulator receiver domain 136 246 3.5E-21 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_2419 e96a3cb101db0873f950baf7a00e7201 258 Pfam PF00072 Response regulator receiver domain 5 119 6.3E-8 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_2419 e96a3cb101db0873f950baf7a00e7201 258 Gene3D G3DSA:3.40.50.2300 131 256 5.4E-28 T 13-10-2018 Astex_0753 14a90bca1d0f16e864bfc13825a9d45d 214 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 48 187 5.2E-10 T 13-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 Astex_0753 14a90bca1d0f16e864bfc13825a9d45d 214 SUPERFAMILY SSF48150 32 200 1.92E-36 T 13-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 Astex_0753 14a90bca1d0f16e864bfc13825a9d45d 214 Gene3D G3DSA:1.10.340.30 39 150 1.1E-59 T 13-10-2018 Astex_0753 14a90bca1d0f16e864bfc13825a9d45d 214 SMART SM00478 51 205 5.6E-5 T 13-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 Astex_0753 14a90bca1d0f16e864bfc13825a9d45d 214 Gene3D G3DSA:1.10.1670.40 16 199 1.1E-59 T 13-10-2018 Astex_2432 bcefa4908cf30e70528da6a29bb17ce2 586 ProSitePatterns PS00211 ABC transporters family signature. 485 499 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Astex_2432 bcefa4908cf30e70528da6a29bb17ce2 586 Gene3D G3DSA:1.20.1560.10 27 339 8.0E-27 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Astex_2432 bcefa4908cf30e70528da6a29bb17ce2 586 Gene3D G3DSA:3.40.50.300 343 586 3.8E-57 T 13-10-2018 Astex_2432 bcefa4908cf30e70528da6a29bb17ce2 586 Pfam PF00005 ABC transporter 369 513 1.5E-22 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_2432 bcefa4908cf30e70528da6a29bb17ce2 586 SUPERFAMILY SSF52540 346 581 2.88E-53 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2432 bcefa4908cf30e70528da6a29bb17ce2 586 SUPERFAMILY SSF90123 27 334 1.83E-22 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Astex_2432 bcefa4908cf30e70528da6a29bb17ce2 586 SMART SM00382 375 560 1.4E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_1916 6b2b02a79f97abb05a91368e16d5e529 543 Gene3D G3DSA:3.20.20.80 25 224 1.5E-40 T 13-10-2018 Astex_1916 6b2b02a79f97abb05a91368e16d5e529 543 Gene3D G3DSA:3.20.20.80 233 428 8.4E-39 T 13-10-2018 Astex_1916 6b2b02a79f97abb05a91368e16d5e529 543 Pfam PF01120 Alpha-L-fucosidase 21 425 2.7E-91 T 13-10-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 Astex_1916 6b2b02a79f97abb05a91368e16d5e529 543 SUPERFAMILY SSF51445 31 428 3.26E-74 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_1916 6b2b02a79f97abb05a91368e16d5e529 543 SMART SM00812 30 488 7.0E-140 T 13-10-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 Astex_1916 6b2b02a79f97abb05a91368e16d5e529 543 Gene3D G3DSA:2.60.40.1180 429 540 1.1E-22 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta Astex_1916 6b2b02a79f97abb05a91368e16d5e529 543 Pfam PF16757 Alpha-L-fucosidase C-terminal domain 453 532 3.3E-9 T 13-10-2018 IPR031919 Alpha-L-fucosidase, C-terminal KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 Astex_0747 ad60d444bbf392d0279b0cb78a314620 338 Gene3D G3DSA:1.10.1040.10 195 338 2.1E-46 T 13-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 Astex_0747 ad60d444bbf392d0279b0cb78a314620 338 Gene3D G3DSA:3.40.50.720 3 192 3.7E-57 T 13-10-2018 Astex_0747 ad60d444bbf392d0279b0cb78a314620 338 SUPERFAMILY SSF48179 185 337 6.97E-48 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Astex_0747 ad60d444bbf392d0279b0cb78a314620 338 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 186 326 2.9E-44 T 13-10-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 Astex_0747 ad60d444bbf392d0279b0cb78a314620 338 SUPERFAMILY SSF51735 11 186 2.67E-46 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_0747 ad60d444bbf392d0279b0cb78a314620 338 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 194 215 - T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 Astex_0747 ad60d444bbf392d0279b0cb78a314620 338 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 12 165 4.4E-42 T 13-10-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 Astex_0747 ad60d444bbf392d0279b0cb78a314620 338 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 179 203 5.3E-35 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 Astex_0747 ad60d444bbf392d0279b0cb78a314620 338 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 244 261 5.3E-35 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 Astex_0747 ad60d444bbf392d0279b0cb78a314620 338 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 204 228 5.3E-35 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 Astex_0747 ad60d444bbf392d0279b0cb78a314620 338 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 15 32 5.3E-35 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 Astex_0747 ad60d444bbf392d0279b0cb78a314620 338 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 139 159 5.3E-35 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 Astex_0747 ad60d444bbf392d0279b0cb78a314620 338 PIRSF PIRSF000114 6 338 1.7E-92 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 Astex_0747 ad60d444bbf392d0279b0cb78a314620 338 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 11 328 34.509 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 Astex_2574 b9a5a4240a230a1422d8b20be1199246 778 Pfam PF07715 TonB-dependent Receptor Plug Domain 52 159 1.3E-9 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_2574 b9a5a4240a230a1422d8b20be1199246 778 Pfam PF00593 TonB dependent receptor 302 775 4.9E-44 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_2574 b9a5a4240a230a1422d8b20be1199246 778 Gene3D G3DSA:2.170.130.10 30 164 2.4E-10 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_2574 b9a5a4240a230a1422d8b20be1199246 778 SUPERFAMILY SSF56935 30 778 4.83E-92 T 13-10-2018 Astex_2574 b9a5a4240a230a1422d8b20be1199246 778 Gene3D G3DSA:2.40.170.20 172 778 3.8E-68 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_1465 6e9813f785119aa11d965a0c23ed9837 381 Gene3D G3DSA:2.40.50.100 64 98 2.9E-10 T 13-10-2018 Astex_1465 6e9813f785119aa11d965a0c23ed9837 381 SUPERFAMILY SSF111369 197 301 3.66E-10 T 13-10-2018 Astex_1465 6e9813f785119aa11d965a0c23ed9837 381 Gene3D G3DSA:2.40.30.170 263 381 3.4E-34 T 13-10-2018 Astex_1465 6e9813f785119aa11d965a0c23ed9837 381 Gene3D G3DSA:1.10.287.470 99 118 2.9E-10 T 13-10-2018 Astex_1465 6e9813f785119aa11d965a0c23ed9837 381 Pfam PF13533 Biotin-lipoyl like 64 113 1.4E-9 T 13-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain Astex_1465 6e9813f785119aa11d965a0c23ed9837 381 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 367 381 2.1E-7 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 Astex_1465 6e9813f785119aa11d965a0c23ed9837 381 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 261 282 2.1E-7 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 Astex_1465 6e9813f785119aa11d965a0c23ed9837 381 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 76 96 2.1E-7 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 Astex_1465 6e9813f785119aa11d965a0c23ed9837 381 SUPERFAMILY SSF111369 62 157 2.88E-8 T 13-10-2018 Astex_1465 6e9813f785119aa11d965a0c23ed9837 381 Gene3D G3DSA:1.10.287.470 131 214 9.2E-11 T 13-10-2018 Astex_1465 6e9813f785119aa11d965a0c23ed9837 381 Pfam PF13437 HlyD family secretion protein 249 360 8.4E-16 T 13-10-2018 Astex_0520 524d7f0a23b45d17f44c376a5483d3d8 407 PIRSF PIRSF000521 18 153 5.3E-8 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Astex_0520 524d7f0a23b45d17f44c376a5483d3d8 407 PIRSF PIRSF000521 171 397 3.8E-35 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Astex_0520 524d7f0a23b45d17f44c376a5483d3d8 407 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 12 397 65.439 T 13-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 Astex_0520 524d7f0a23b45d17f44c376a5483d3d8 407 Pfam PF00202 Aminotransferase class-III 21 393 3.0E-107 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Astex_0520 524d7f0a23b45d17f44c376a5483d3d8 407 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 220 257 - T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Astex_0520 524d7f0a23b45d17f44c376a5483d3d8 407 Gene3D G3DSA:3.40.640.10 56 302 1.1E-130 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Astex_0520 524d7f0a23b45d17f44c376a5483d3d8 407 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 14 394 2.2E-129 T 13-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 Astex_0520 524d7f0a23b45d17f44c376a5483d3d8 407 SUPERFAMILY SSF53383 13 394 2.2E-117 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Astex_0520 524d7f0a23b45d17f44c376a5483d3d8 407 Gene3D G3DSA:3.90.1150.10 26 386 1.1E-130 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Astex_2325 43c579ac2ae790f3e68d2325dca61375 473 SUPERFAMILY SSF53686 8 467 3.57E-131 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme Astex_2325 43c579ac2ae790f3e68d2325dca61375 473 Gene3D G3DSA:3.40.50.1100 103 437 8.3E-123 T 13-10-2018 Astex_2325 43c579ac2ae790f3e68d2325dca61375 473 Pfam PF14821 Threonine synthase N terminus 10 84 2.8E-14 T 13-10-2018 IPR029144 Threonine synthase, N-terminal Astex_2325 43c579ac2ae790f3e68d2325dca61375 473 TIGRFAM TIGR00260 thrC: threonine synthase 85 438 8.0E-71 T 13-10-2018 IPR004450 Threonine synthase-like Astex_2325 43c579ac2ae790f3e68d2325dca61375 473 Gene3D G3DSA:3.40.50.1100 115 446 8.3E-123 T 13-10-2018 Astex_2325 43c579ac2ae790f3e68d2325dca61375 473 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 102 415 4.4E-19 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme Astex_2325 43c579ac2ae790f3e68d2325dca61375 473 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 109 123 - T 13-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 Astex_2325 43c579ac2ae790f3e68d2325dca61375 473 Gene3D G3DSA:3.90.1380.10 5 95 3.5E-15 T 13-10-2018 IPR037158 Threonine synthase, N-terminal domain superfamily Astex_1077 0757ff3ddcedd828ff4ea43fec8a3983 288 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 16 33 3.9E-26 T 13-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) Astex_1077 0757ff3ddcedd828ff4ea43fec8a3983 288 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 194 211 3.9E-26 T 13-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) Astex_1077 0757ff3ddcedd828ff4ea43fec8a3983 288 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 156 176 3.9E-26 T 13-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) Astex_1077 0757ff3ddcedd828ff4ea43fec8a3983 288 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 236 254 3.9E-26 T 13-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) Astex_1077 0757ff3ddcedd828ff4ea43fec8a3983 288 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 92 113 3.9E-26 T 13-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) Astex_1077 0757ff3ddcedd828ff4ea43fec8a3983 288 SUPERFAMILY SSF63829 10 270 1.57E-53 T 13-10-2018 Astex_1077 0757ff3ddcedd828ff4ea43fec8a3983 288 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 15 254 2.9E-71 T 13-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region Astex_1077 0757ff3ddcedd828ff4ea43fec8a3983 288 Gene3D G3DSA:2.120.10.30 3 280 7.6E-81 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like Astex_3285 5b3e2510636f9ffefdbdf3c715b3d15d 726 Gene3D G3DSA:3.30.365.10 316 535 1.4E-57 T 13-10-2018 Astex_3285 5b3e2510636f9ffefdbdf3c715b3d15d 726 Gene3D G3DSA:3.90.1170.50 172 303 4.6E-6 T 13-10-2018 Astex_3285 5b3e2510636f9ffefdbdf3c715b3d15d 726 Gene3D G3DSA:3.30.365.10 35 170 1.6E-21 T 13-10-2018 Astex_3285 5b3e2510636f9ffefdbdf3c715b3d15d 726 Gene3D G3DSA:3.30.365.10 340 431 1.4E-57 T 13-10-2018 Astex_3285 5b3e2510636f9ffefdbdf3c715b3d15d 726 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 593 672 2.0E-8 T 13-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Astex_3285 5b3e2510636f9ffefdbdf3c715b3d15d 726 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 36 170 5.3E-14 T 13-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Astex_3285 5b3e2510636f9ffefdbdf3c715b3d15d 726 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 314 607 1.2E-43 T 13-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Astex_3285 5b3e2510636f9ffefdbdf3c715b3d15d 726 SMART SM01008 201 288 6.0E-13 T 13-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead Astex_3285 5b3e2510636f9ffefdbdf3c715b3d15d 726 Gene3D G3DSA:3.30.365.10 577 726 1.2E-33 T 13-10-2018 Astex_3285 5b3e2510636f9ffefdbdf3c715b3d15d 726 SUPERFAMILY SSF56003 311 722 1.74E-104 T 13-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 Astex_3285 5b3e2510636f9ffefdbdf3c715b3d15d 726 PIRSF PIRSF036389 1 725 6.3E-218 T 13-10-2018 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related Astex_3285 5b3e2510636f9ffefdbdf3c715b3d15d 726 SUPERFAMILY SSF56003 14 233 2.86E-36 T 13-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 Astex_0690 8102cb72329cead22707c5eddb1b24df 432 Gene3D G3DSA:2.115.10.20 109 431 6.4E-58 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Astex_0690 8102cb72329cead22707c5eddb1b24df 432 SUPERFAMILY SSF75005 107 425 4.19E-50 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Astex_0690 8102cb72329cead22707c5eddb1b24df 432 Pfam PF04041 beta-1,4-mannooligosaccharide phosphorylase 206 429 1.1E-26 T 13-10-2018 IPR007184 Mannoside phosphorylase Astex_0939 be828470381d2b9c53cdded69c3abb90 157 Pfam PF00177 Ribosomal protein S7p/S5e 1 150 2.9E-67 T 13-10-2018 IPR023798 Ribosomal protein S7 domain Astex_0939 be828470381d2b9c53cdded69c3abb90 157 Gene3D G3DSA:1.10.455.10 2 156 5.8E-62 T 13-10-2018 IPR036823 Ribosomal protein S7 domain superfamily Astex_0939 be828470381d2b9c53cdded69c3abb90 157 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 13-10-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0939 be828470381d2b9c53cdded69c3abb90 157 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 157 36.433 T 13-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 Astex_0939 be828470381d2b9c53cdded69c3abb90 157 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 157 3.8E-68 T 13-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 Astex_0939 be828470381d2b9c53cdded69c3abb90 157 SUPERFAMILY SSF47973 3 150 2.62E-60 T 13-10-2018 IPR036823 Ribosomal protein S7 domain superfamily Astex_0939 be828470381d2b9c53cdded69c3abb90 157 PIRSF PIRSF002122 2 157 5.7E-60 T 13-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 Astex_2941 032cf3a4e859ec68e018895c40582f17 216 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 3 209 3.0E-55 T 13-10-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 Astex_2941 032cf3a4e859ec68e018895c40582f17 216 SUPERFAMILY SSF53597 3 210 6.15E-60 T 13-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 Astex_2941 032cf3a4e859ec68e018895c40582f17 216 Gene3D G3DSA:3.40.430.10 2 215 6.4E-69 T 13-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 Astex_2941 032cf3a4e859ec68e018895c40582f17 216 Pfam PF01872 RibD C-terminal domain 4 209 1.6E-47 T 13-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 Astex_1771 187eb0078ecf75a4fa19afcba594005c 449 Pfam PF00709 Adenylosuccinate synthetase 25 441 1.6E-169 T 13-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 Astex_1771 187eb0078ecf75a4fa19afcba594005c 449 Gene3D G3DSA:3.40.440.10 26 278 5.7E-92 T 13-10-2018 Astex_1771 187eb0078ecf75a4fa19afcba594005c 449 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 152 163 - T 13-10-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 Astex_1771 187eb0078ecf75a4fa19afcba594005c 449 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 26 447 8.2E-157 T 13-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 Astex_1771 187eb0078ecf75a4fa19afcba594005c 449 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 449 201.916 T 13-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 Astex_1771 187eb0078ecf75a4fa19afcba594005c 449 Gene3D G3DSA:1.10.300.10 121 219 5.7E-92 T 13-10-2018 Astex_1771 187eb0078ecf75a4fa19afcba594005c 449 SUPERFAMILY SSF52540 21 442 2.34E-166 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1771 187eb0078ecf75a4fa19afcba594005c 449 SMART SM00788 23 442 2.1E-278 T 13-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 Astex_1771 187eb0078ecf75a4fa19afcba594005c 449 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 30 37 - T 13-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 Astex_1771 187eb0078ecf75a4fa19afcba594005c 449 Gene3D G3DSA:3.90.170.10 285 449 3.7E-67 T 13-10-2018 Astex_2839 ec7a141bc0a40f1389283cd13f01c3e7 439 SUPERFAMILY SSF52954 334 437 5.4E-27 T 13-10-2018 Astex_2839 ec7a141bc0a40f1389283cd13f01c3e7 439 Hamap MF_01570 Proline--tRNA ligase [proS]. 1 437 63.121 T 13-10-2018 IPR023716 Proline-tRNA ligase, class IIa, type 2 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 Astex_2839 ec7a141bc0a40f1389283cd13f01c3e7 439 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 327 1.2E-36 T 13-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Astex_2839 ec7a141bc0a40f1389283cd13f01c3e7 439 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 8.4E-14 T 13-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 Astex_2839 ec7a141bc0a40f1389283cd13f01c3e7 439 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 8.4E-14 T 13-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 Astex_2839 ec7a141bc0a40f1389283cd13f01c3e7 439 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 8.4E-14 T 13-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 Astex_2839 ec7a141bc0a40f1389283cd13f01c3e7 439 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 8.4E-14 T 13-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 Astex_2839 ec7a141bc0a40f1389283cd13f01c3e7 439 Gene3D G3DSA:3.30.930.10 1 330 1.9E-107 T 13-10-2018 Astex_2839 ec7a141bc0a40f1389283cd13f01c3e7 439 Pfam PF03129 Anticodon binding domain 345 436 2.9E-16 T 13-10-2018 IPR004154 Anticodon-binding Astex_2839 ec7a141bc0a40f1389283cd13f01c3e7 439 Gene3D G3DSA:3.40.50.800 331 439 1.1E-26 T 13-10-2018 IPR036621 Anticodon-binding domain superfamily Astex_2839 ec7a141bc0a40f1389283cd13f01c3e7 439 SUPERFAMILY SSF55681 10 348 1.6E-90 T 13-10-2018 Astex_2839 ec7a141bc0a40f1389283cd13f01c3e7 439 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 223 3.9E-101 T 13-10-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 Astex_0929 0a07bcb5f06b246eccc33eb5b806dfde 158 Gene3D G3DSA:3.30.70.640 3 157 2.6E-59 T 13-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Astex_0929 0a07bcb5f06b246eccc33eb5b806dfde 158 SUPERFAMILY SSF55040 13 155 2.35E-54 T 13-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Astex_0929 0a07bcb5f06b246eccc33eb5b806dfde 158 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase [moaC]. 4 157 31.635 T 13-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Astex_0929 0a07bcb5f06b246eccc33eb5b806dfde 158 Pfam PF01967 MoaC family 17 152 9.6E-50 T 13-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Astex_0929 0a07bcb5f06b246eccc33eb5b806dfde 158 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 6 153 3.1E-56 T 13-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Astex_2502 66ceaac2777256329887c7141b5687e3 356 SUPERFAMILY SSF52540 15 279 3.11E-62 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2502 66ceaac2777256329887c7141b5687e3 356 ProSitePatterns PS00321 recA signature. 225 233 - T 13-10-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 Astex_2502 66ceaac2777256329887c7141b5687e3 356 Gene3D G3DSA:3.30.250.10 281 338 3.6E-23 T 13-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal Astex_2502 66ceaac2777256329887c7141b5687e3 356 Hamap MF_00268 Protein RecA [recA]. 16 341 51.337 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Astex_2502 66ceaac2777256329887c7141b5687e3 356 Pfam PF00154 recA bacterial DNA recombination protein 18 280 3.7E-144 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Astex_2502 66ceaac2777256329887c7141b5687e3 356 PRINTS PR00142 RecA protein signature 177 206 2.0E-85 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Astex_2502 66ceaac2777256329887c7141b5687e3 356 PRINTS PR00142 RecA protein signature 222 250 2.0E-85 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Astex_2502 66ceaac2777256329887c7141b5687e3 356 PRINTS PR00142 RecA protein signature 255 284 2.0E-85 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Astex_2502 66ceaac2777256329887c7141b5687e3 356 PRINTS PR00142 RecA protein signature 105 134 2.0E-85 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Astex_2502 66ceaac2777256329887c7141b5687e3 356 PRINTS PR00142 RecA protein signature 139 168 2.0E-85 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Astex_2502 66ceaac2777256329887c7141b5687e3 356 PRINTS PR00142 RecA protein signature 309 326 2.0E-85 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Astex_2502 66ceaac2777256329887c7141b5687e3 356 Gene3D G3DSA:3.40.50.300 40 280 3.9E-81 T 13-10-2018 Astex_2502 66ceaac2777256329887c7141b5687e3 356 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 15 335 5.1E-171 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 Astex_2502 66ceaac2777256329887c7141b5687e3 356 SUPERFAMILY SSF54752 280 337 1.1E-19 T 13-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal Astex_2502 66ceaac2777256329887c7141b5687e3 356 SMART SM00382 69 240 2.2E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_0033 a4bef69d7e3461f0e8cd8e2dc75d4440 565 Pfam PF08448 PAS fold 149 255 4.2E-14 T 13-10-2018 IPR013656 PAS fold-4 Astex_0033 a4bef69d7e3461f0e8cd8e2dc75d4440 565 Gene3D G3DSA:3.30.450.20 16 142 4.4E-23 T 13-10-2018 Astex_0033 a4bef69d7e3461f0e8cd8e2dc75d4440 565 SUPERFAMILY SSF55785 272 377 3.84E-23 T 13-10-2018 IPR035965 PAS domain superfamily Astex_0033 a4bef69d7e3461f0e8cd8e2dc75d4440 565 Gene3D G3DSA:3.30.450.20 274 371 4.1E-18 T 13-10-2018 Astex_0033 a4bef69d7e3461f0e8cd8e2dc75d4440 565 Pfam PF08447 PAS fold 40 126 5.5E-14 T 13-10-2018 IPR013655 PAS fold-3 GO:0005515 Astex_0033 a4bef69d7e3461f0e8cd8e2dc75d4440 565 Pfam PF08447 PAS fold 284 369 3.7E-12 T 13-10-2018 IPR013655 PAS fold-3 GO:0005515 Astex_0033 a4bef69d7e3461f0e8cd8e2dc75d4440 565 SMART SM00283 366 565 6.6E-5 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_0033 a4bef69d7e3461f0e8cd8e2dc75d4440 565 SMART SM00086 212 254 1.6 T 13-10-2018 IPR001610 PAC motif Astex_0033 a4bef69d7e3461f0e8cd8e2dc75d4440 565 SMART SM00086 334 376 0.023 T 13-10-2018 IPR001610 PAC motif Astex_0033 a4bef69d7e3461f0e8cd8e2dc75d4440 565 SMART SM00086 90 132 4.7E-6 T 13-10-2018 IPR001610 PAC motif Astex_0033 a4bef69d7e3461f0e8cd8e2dc75d4440 565 SUPERFAMILY SSF55785 28 133 2.42E-24 T 13-10-2018 IPR035965 PAS domain superfamily Astex_0033 a4bef69d7e3461f0e8cd8e2dc75d4440 565 SUPERFAMILY SSF55785 149 251 6.46E-22 T 13-10-2018 IPR035965 PAS domain superfamily Astex_0033 a4bef69d7e3461f0e8cd8e2dc75d4440 565 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 146 256 5.1E-15 T 13-10-2018 IPR000014 PAS domain Astex_0033 a4bef69d7e3461f0e8cd8e2dc75d4440 565 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 271 377 3.1E-13 T 13-10-2018 IPR000014 PAS domain Astex_0033 a4bef69d7e3461f0e8cd8e2dc75d4440 565 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 23 133 3.0E-16 T 13-10-2018 IPR000014 PAS domain Astex_0033 a4bef69d7e3461f0e8cd8e2dc75d4440 565 Gene3D G3DSA:3.30.450.20 143 273 2.6E-21 T 13-10-2018 Astex_0033 a4bef69d7e3461f0e8cd8e2dc75d4440 565 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 378 407 8.0E-5 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_0033 a4bef69d7e3461f0e8cd8e2dc75d4440 565 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 477 506 8.0E-5 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_0033 a4bef69d7e3461f0e8cd8e2dc75d4440 565 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 409 557 3.0E-24 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_0033 a4bef69d7e3461f0e8cd8e2dc75d4440 565 SUPERFAMILY SSF58104 377 562 1.44E-40 T 13-10-2018 Astex_0033 a4bef69d7e3461f0e8cd8e2dc75d4440 565 SMART SM00091 139 207 2.1 T 13-10-2018 IPR000014 PAS domain Astex_0033 a4bef69d7e3461f0e8cd8e2dc75d4440 565 SMART SM00091 18 85 0.17 T 13-10-2018 IPR000014 PAS domain Astex_0033 a4bef69d7e3461f0e8cd8e2dc75d4440 565 SMART SM00091 259 329 2.3 T 13-10-2018 IPR000014 PAS domain Astex_0033 a4bef69d7e3461f0e8cd8e2dc75d4440 565 Gene3D G3DSA:1.10.287.950 372 565 3.9E-37 T 13-10-2018 Astex_1801 02e93f5bdffc00d1b8daa5eecd3635cc 316 Pfam PF01545 Cation efflux family 28 247 1.2E-32 T 13-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 Astex_1801 02e93f5bdffc00d1b8daa5eecd3635cc 316 Gene3D G3DSA:1.20.1510.10 18 169 2.5E-21 T 13-10-2018 IPR027469 Cation efflux transmembrane domain superfamily Astex_1801 02e93f5bdffc00d1b8daa5eecd3635cc 316 Gene3D G3DSA:1.20.1510.10 172 247 1.9E-9 T 13-10-2018 IPR027469 Cation efflux transmembrane domain superfamily Astex_1801 02e93f5bdffc00d1b8daa5eecd3635cc 316 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 19 294 4.9E-65 T 13-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 Astex_1801 02e93f5bdffc00d1b8daa5eecd3635cc 316 SUPERFAMILY SSF161111 16 248 4.84E-49 T 13-10-2018 IPR027469 Cation efflux transmembrane domain superfamily Astex_2732 f48f5739328abb2a4733f9eba787d783 572 SUPERFAMILY SSF52374 3 394 1.75E-80 T 13-10-2018 Astex_2732 f48f5739328abb2a4733f9eba787d783 572 Hamap MF_00098 Methionine--tRNA ligase [metG]. 2 565 37.304 T 13-10-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Astex_2732 f48f5739328abb2a4733f9eba787d783 572 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 4 555 3.2E-141 T 13-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 Astex_2732 f48f5739328abb2a4733f9eba787d783 572 Gene3D G3DSA:3.40.50.620 4 389 2.8E-141 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Astex_2732 f48f5739328abb2a4733f9eba787d783 572 SUPERFAMILY SSF47323 399 566 2.24E-34 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Astex_2732 f48f5739328abb2a4733f9eba787d783 572 PRINTS PR01041 Methionyl-tRNA synthetase signature 39 53 1.4E-27 T 13-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 Astex_2732 f48f5739328abb2a4733f9eba787d783 572 PRINTS PR01041 Methionyl-tRNA synthetase signature 256 267 1.4E-27 T 13-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 Astex_2732 f48f5739328abb2a4733f9eba787d783 572 PRINTS PR01041 Methionyl-tRNA synthetase signature 87 98 1.4E-27 T 13-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 Astex_2732 f48f5739328abb2a4733f9eba787d783 572 PRINTS PR01041 Methionyl-tRNA synthetase signature 300 315 1.4E-27 T 13-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 Astex_2732 f48f5739328abb2a4733f9eba787d783 572 PRINTS PR01041 Methionyl-tRNA synthetase signature 394 405 1.4E-27 T 13-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 Astex_2732 f48f5739328abb2a4733f9eba787d783 572 PRINTS PR01041 Methionyl-tRNA synthetase signature 6 19 1.4E-27 T 13-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 Astex_2732 f48f5739328abb2a4733f9eba787d783 572 Gene3D G3DSA:1.10.730.10 390 565 2.5E-38 T 13-10-2018 Astex_2732 f48f5739328abb2a4733f9eba787d783 572 Gene3D G3DSA:2.20.28.20 139 173 2.8E-141 T 13-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Astex_2732 f48f5739328abb2a4733f9eba787d783 572 Pfam PF09334 tRNA synthetases class I (M) 4 406 3.6E-141 T 13-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 Astex_2732 f48f5739328abb2a4733f9eba787d783 572 SUPERFAMILY SSF57770 139 173 3.79E-13 T 13-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Astex_2431 354388c3ac9d8a462fa21b0ed820e7a5 152 Pfam PF10074 Uncharacterized conserved protein (DUF2285) 57 152 3.4E-19 T 13-10-2018 IPR018754 Protein of unknown function DUF2285 Astex_2602 e238b6e1e50bf25a9c56b77bb79bb7f1 958 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 42 213 5.2E-23 T 13-10-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_2602 e238b6e1e50bf25a9c56b77bb79bb7f1 958 Gene3D G3DSA:3.20.20.80 330 616 6.0E-86 T 13-10-2018 Astex_2602 e238b6e1e50bf25a9c56b77bb79bb7f1 958 Gene3D G3DSA:2.60.40.10 697 775 8.8E-20 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_2602 e238b6e1e50bf25a9c56b77bb79bb7f1 958 Gene3D G3DSA:2.60.40.10 217 328 6.2E-27 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_2602 e238b6e1e50bf25a9c56b77bb79bb7f1 958 Pfam PF16355 Domain of unknown function (DUF4982) 631 689 5.1E-23 T 13-10-2018 IPR032311 Domain of unknown function DUF4982 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_2602 e238b6e1e50bf25a9c56b77bb79bb7f1 958 SUPERFAMILY SSF51445 333 617 1.08E-63 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_2602 e238b6e1e50bf25a9c56b77bb79bb7f1 958 Gene3D G3DSA:2.60.120.260 28 215 3.7E-49 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_2602 e238b6e1e50bf25a9c56b77bb79bb7f1 958 SUPERFAMILY SSF49303 221 328 2.79E-18 T 13-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily Astex_2602 e238b6e1e50bf25a9c56b77bb79bb7f1 958 Gene3D G3DSA:2.60.40.10 618 696 6.1E-31 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_2602 e238b6e1e50bf25a9c56b77bb79bb7f1 958 SUPERFAMILY SSF49785 16 216 1.34E-45 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_2602 e238b6e1e50bf25a9c56b77bb79bb7f1 958 Pfam PF00703 Glycosyl hydrolases family 2 223 328 5.7E-16 T 13-10-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_2602 e238b6e1e50bf25a9c56b77bb79bb7f1 958 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 335 524 7.5E-27 T 13-10-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 Astex_2602 e238b6e1e50bf25a9c56b77bb79bb7f1 958 ProSitePatterns PS00608 Glycosyl hydrolases family 2 acid/base catalyst. 429 443 - T 13-10-2018 IPR023232 Glycoside hydrolase, family 2, active site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_2602 e238b6e1e50bf25a9c56b77bb79bb7f1 958 PRINTS PR00132 Glycosyl hydrolase family 2 signature 429 444 2.9E-10 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_2602 e238b6e1e50bf25a9c56b77bb79bb7f1 958 PRINTS PR00132 Glycosyl hydrolase family 2 signature 147 162 2.9E-10 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_2602 e238b6e1e50bf25a9c56b77bb79bb7f1 958 PRINTS PR00132 Glycosyl hydrolase family 2 signature 340 354 2.9E-10 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_1349 97c64240c93238e7d01061ea3220e66a 468 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 267 444 6.1E-34 T 13-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Astex_1349 97c64240c93238e7d01061ea3220e66a 468 SUPERFAMILY SSF55681 121 464 1.06E-88 T 13-10-2018 Astex_1349 97c64240c93238e7d01061ea3220e66a 468 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 112 4.8E-23 T 13-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 Astex_1349 97c64240c93238e7d01061ea3220e66a 468 TIGRFAM TIGR00414 serS: serine--tRNA ligase 254 461 3.3E-98 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 Astex_1349 97c64240c93238e7d01061ea3220e66a 468 PRINTS PR00981 Seryl-tRNA synthetase signature 395 411 8.2E-31 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 Astex_1349 97c64240c93238e7d01061ea3220e66a 468 PRINTS PR00981 Seryl-tRNA synthetase signature 308 320 8.2E-31 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 Astex_1349 97c64240c93238e7d01061ea3220e66a 468 PRINTS PR00981 Seryl-tRNA synthetase signature 377 393 8.2E-31 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 Astex_1349 97c64240c93238e7d01061ea3220e66a 468 PRINTS PR00981 Seryl-tRNA synthetase signature 320 333 8.2E-31 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 Astex_1349 97c64240c93238e7d01061ea3220e66a 468 PRINTS PR00981 Seryl-tRNA synthetase signature 360 373 8.2E-31 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 Astex_1349 97c64240c93238e7d01061ea3220e66a 468 Gene3D G3DSA:1.10.287.40 3 109 2.4E-18 T 13-10-2018 Astex_1349 97c64240c93238e7d01061ea3220e66a 468 SUPERFAMILY SSF46589 1 117 3.5E-22 T 13-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 Astex_1349 97c64240c93238e7d01061ea3220e66a 468 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 466 38.593 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 Astex_1349 97c64240c93238e7d01061ea3220e66a 468 PIRSF PIRSF001529 1 239 1.4E-55 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 Astex_1349 97c64240c93238e7d01061ea3220e66a 468 PIRSF PIRSF001529 241 468 3.9E-98 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 Astex_1349 97c64240c93238e7d01061ea3220e66a 468 Gene3D G3DSA:3.30.930.10 110 468 1.2E-110 T 13-10-2018 Astex_0581 1fa90aece6a91dbbf0c44b32b22277ff 163 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 4.9E-14 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 Astex_0581 1fa90aece6a91dbbf0c44b32b22277ff 163 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 4.9E-14 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 Astex_0581 1fa90aece6a91dbbf0c44b32b22277ff 163 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 4.9E-14 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 Astex_0581 1fa90aece6a91dbbf0c44b32b22277ff 163 SUPERFAMILY SSF46785 5 64 1.76E-16 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_0581 1fa90aece6a91dbbf0c44b32b22277ff 163 SUPERFAMILY SSF54909 69 153 7.78E-19 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel Astex_0581 1fa90aece6a91dbbf0c44b32b22277ff 163 Gene3D G3DSA:3.30.70.920 58 141 3.9E-22 T 13-10-2018 Astex_0581 1fa90aece6a91dbbf0c44b32b22277ff 163 Pfam PF01037 Lrp/AsnC ligand binding domain 73 144 1.9E-20 T 13-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Astex_0581 1fa90aece6a91dbbf0c44b32b22277ff 163 Gene3D G3DSA:1.10.10.10 5 57 6.7E-24 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_0581 1fa90aece6a91dbbf0c44b32b22277ff 163 Pfam PF13412 Winged helix-turn-helix DNA-binding 6 52 2.0E-18 T 13-10-2018 Astex_0581 1fa90aece6a91dbbf0c44b32b22277ff 163 ProSitePatterns PS00519 AsnC-type HTH domain signature. 23 49 - T 13-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site Astex_0581 1fa90aece6a91dbbf0c44b32b22277ff 163 SMART SM00344 5 114 2.7E-42 T 13-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 Astex_2271 55357a6549559aaa69f53e4e60930dc2 257 SUPERFAMILY SSF51735 1 147 2.32E-8 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_2271 55357a6549559aaa69f53e4e60930dc2 257 Gene3D G3DSA:3.40.50.720 1 225 6.8E-10 T 13-10-2018 Astex_2738 a833f63321f7458f6e30f15a4e9204ae 138 Pfam PF05656 Protein of unknown function (DUF805) 9 118 6.3E-20 T 13-10-2018 IPR008523 Protein of unknown function DUF805 GO:0016021 Astex_2595 e969aae021dabc5e2da8815c73ae845b 796 Pfam PF15979 Glycosyl hydrolase family 115 173 512 3.0E-125 T 13-10-2018 IPR031924 Glycosyl hydrolase family 115 Astex_2595 e969aae021dabc5e2da8815c73ae845b 796 Gene3D G3DSA:3.20.20.520 176 468 1.1E-112 T 13-10-2018 Astex_2595 e969aae021dabc5e2da8815c73ae845b 796 Gene3D G3DSA:3.30.379.10 15 175 2.5E-41 T 13-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 Astex_2595 e969aae021dabc5e2da8815c73ae845b 796 Gene3D G3DSA:1.20.58.2150 472 632 5.7E-14 T 13-10-2018 Astex_2501 3197b8d42a428f97f62a3028dc9314e9 105 SUPERFAMILY SSF46785 1 98 6.28E-16 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_2501 3197b8d42a428f97f62a3028dc9314e9 105 Gene3D G3DSA:1.10.10.10 6 99 4.1E-26 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_2501 3197b8d42a428f97f62a3028dc9314e9 105 Pfam PF13601 Winged helix DNA-binding domain 18 96 5.0E-27 T 13-10-2018 IPR027395 Winged helix DNA-binding domain Astex_3292 efce3a3af9787e9678e2ecd254876a08 536 Gene3D G3DSA:1.50.10.20 79 407 3.4E-81 T 13-10-2018 Astex_3292 efce3a3af9787e9678e2ecd254876a08 536 SUPERFAMILY SSF81853 30 390 1.7E-72 T 13-10-2018 Astex_3292 efce3a3af9787e9678e2ecd254876a08 536 Pfam PF09492 Pectic acid lyase 158 342 1.5E-28 T 13-10-2018 IPR012669 Pectic acid lyase Astex_1012 bda7cb2f144f716d8a1a7a7aafcc82f3 359 Gene3D G3DSA:3.30.450.20 164 267 5.9E-7 T 13-10-2018 Astex_1012 bda7cb2f144f716d8a1a7a7aafcc82f3 359 Gene3D G3DSA:1.10.287.950 2 147 5.4E-17 T 13-10-2018 Astex_1012 bda7cb2f144f716d8a1a7a7aafcc82f3 359 SUPERFAMILY SSF58104 21 113 1.7E-17 T 13-10-2018 Astex_1012 bda7cb2f144f716d8a1a7a7aafcc82f3 359 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 72 101 8.7E-7 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_1012 bda7cb2f144f716d8a1a7a7aafcc82f3 359 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 43 70 8.7E-7 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_1012 bda7cb2f144f716d8a1a7a7aafcc82f3 359 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 40 115 1.2E-12 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_3246 5751026f4a73076825ee389b5e4f64d4 418 SUPERFAMILY SSF55021 339 415 2.14E-23 T 13-10-2018 Astex_3246 5751026f4a73076825ee389b5e4f64d4 418 Pfam PF00696 Amino acid kinase family 3 234 3.0E-46 T 13-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 Astex_3246 5751026f4a73076825ee389b5e4f64d4 418 PIRSF PIRSF000726 63 417 1.4E-122 T 13-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 Astex_3246 5751026f4a73076825ee389b5e4f64d4 418 PIRSF PIRSF000726 1 64 1.0E-15 T 13-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 Astex_3246 5751026f4a73076825ee389b5e4f64d4 418 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 65 411 2.2E-112 T 13-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 Astex_3246 5751026f4a73076825ee389b5e4f64d4 418 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 4 413 1.9E-127 T 13-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 Astex_3246 5751026f4a73076825ee389b5e4f64d4 418 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 13-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 Astex_3246 5751026f4a73076825ee389b5e4f64d4 418 Pfam PF01842 ACT domain 276 336 3.2E-10 T 13-10-2018 IPR002912 ACT domain Astex_3246 5751026f4a73076825ee389b5e4f64d4 418 Pfam PF13840 ACT domain 346 408 1.3E-16 T 13-10-2018 IPR027795 CASTOR, ACT domain Astex_3246 5751026f4a73076825ee389b5e4f64d4 418 SUPERFAMILY SSF55021 257 336 1.2E-14 T 13-10-2018 Astex_3246 5751026f4a73076825ee389b5e4f64d4 418 SUPERFAMILY SSF53633 3 253 1.83E-68 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Astex_3246 5751026f4a73076825ee389b5e4f64d4 418 Gene3D G3DSA:3.40.1160.10 1 263 2.4E-79 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Astex_3246 5751026f4a73076825ee389b5e4f64d4 418 Gene3D G3DSA:3.30.70.260 264 413 1.2E-54 T 13-10-2018 Astex_3246 5751026f4a73076825ee389b5e4f64d4 418 Gene3D G3DSA:3.30.70.260 270 348 1.2E-54 T 13-10-2018 Astex_0331 6c7cb587509b19c56445c3b35680ea32 433 SUPERFAMILY SSF56563 139 432 2.22E-66 T 13-10-2018 Astex_0331 6c7cb587509b19c56445c3b35680ea32 433 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 43 431 3.7E-110 T 13-10-2018 IPR024455 Phage capsid Astex_0331 6c7cb587509b19c56445c3b35680ea32 433 Pfam PF05065 Phage capsid family 146 430 1.1E-76 T 13-10-2018 IPR024455 Phage capsid Astex_2890 c4a12d2b477b9c1b293f0f725569f760 484 Gene3D G3DSA:1.25.40.80 126 291 3.4E-79 T 13-10-2018 Astex_2890 c4a12d2b477b9c1b293f0f725569f760 484 Gene3D G3DSA:3.40.50.620 6 207 3.4E-79 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Astex_2890 c4a12d2b477b9c1b293f0f725569f760 484 Gene3D G3DSA:1.10.579.10 295 484 7.2E-67 T 13-10-2018 Astex_2890 c4a12d2b477b9c1b293f0f725569f760 484 ProSitePatterns PS00691 DNA photolyases class 1 signature 2. 346 365 - T 13-10-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal Astex_2890 c4a12d2b477b9c1b293f0f725569f760 484 Pfam PF03441 FAD binding domain of DNA photolyase 277 479 1.5E-71 T 13-10-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-400253 Astex_2890 c4a12d2b477b9c1b293f0f725569f760 484 SUPERFAMILY SSF52425 4 175 3.4E-44 T 13-10-2018 IPR036155 Cryptochrome/photolyase, N-terminal domain superfamily Reactome: R-HSA-400253 Astex_2890 c4a12d2b477b9c1b293f0f725569f760 484 SUPERFAMILY SSF48173 202 483 8.76E-98 T 13-10-2018 IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily Reactome: R-HSA-400253 Astex_2890 c4a12d2b477b9c1b293f0f725569f760 484 Pfam PF00875 DNA photolyase 6 157 5.7E-40 T 13-10-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-400253 Astex_2890 c4a12d2b477b9c1b293f0f725569f760 484 PRINTS PR00147 DNA photolyase signature 346 364 2.9E-23 T 13-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 Astex_2890 c4a12d2b477b9c1b293f0f725569f760 484 PRINTS PR00147 DNA photolyase signature 385 399 2.9E-23 T 13-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 Astex_2890 c4a12d2b477b9c1b293f0f725569f760 484 PRINTS PR00147 DNA photolyase signature 326 342 2.9E-23 T 13-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 Astex_2890 c4a12d2b477b9c1b293f0f725569f760 484 PRINTS PR00147 DNA photolyase signature 137 153 2.9E-23 T 13-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 Astex_1808 96860380ff693c6f60aafb989de74cb3 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 26 37 7.3E-16 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 Astex_1808 96860380ff693c6f60aafb989de74cb3 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 10 26 7.3E-16 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 Astex_1808 96860380ff693c6f60aafb989de74cb3 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 37 56 7.3E-16 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 Astex_1808 96860380ff693c6f60aafb989de74cb3 154 Pfam PF13404 AsnC-type helix-turn-helix domain 10 51 2.6E-14 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 Astex_1808 96860380ff693c6f60aafb989de74cb3 154 SMART SM00344 10 119 7.9E-37 T 13-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 Astex_1808 96860380ff693c6f60aafb989de74cb3 154 ProSitePatterns PS00519 AsnC-type HTH domain signature. 28 54 - T 13-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site Astex_1808 96860380ff693c6f60aafb989de74cb3 154 Gene3D G3DSA:1.10.10.10 2 64 2.0E-21 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1808 96860380ff693c6f60aafb989de74cb3 154 SUPERFAMILY SSF54909 73 152 4.29E-16 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel Astex_1808 96860380ff693c6f60aafb989de74cb3 154 Gene3D G3DSA:3.30.70.920 65 147 4.8E-20 T 13-10-2018 Astex_1808 96860380ff693c6f60aafb989de74cb3 154 SUPERFAMILY SSF46785 10 67 5.99E-15 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_1808 96860380ff693c6f60aafb989de74cb3 154 Pfam PF01037 Lrp/AsnC ligand binding domain 76 149 1.3E-17 T 13-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Astex_1036 7e35f708d93872ef363e45d57dc993ed 476 Pfam PF12679 ABC-2 family transporter protein 5 263 2.9E-18 T 13-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 Astex_1036 7e35f708d93872ef363e45d57dc993ed 476 Pfam PF12040 Domain of unknown function (DUF3526) 273 434 3.6E-45 T 13-10-2018 IPR021913 Protein of unknown function DUF3526 Astex_1036 7e35f708d93872ef363e45d57dc993ed 476 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 13 51 1.0E-5 T 13-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain Astex_0769 9bc648e9a264a6e5f60baf96eed85a7c 112 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 38 96 3.1E-5 T 13-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 Astex_0769 9bc648e9a264a6e5f60baf96eed85a7c 112 SUPERFAMILY SSF101386 16 102 9.53E-13 T 13-10-2018 Astex_0769 9bc648e9a264a6e5f60baf96eed85a7c 112 Gene3D G3DSA:1.10.287.1080 11 103 4.8E-15 T 13-10-2018 Astex_2441 8a93d9b2fdd652057ab89690c7104e85 205 ProSitePatterns PS01081 TetR-type HTH domain signature. 34 64 - T 13-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site Astex_2441 8a93d9b2fdd652057ab89690c7104e85 205 Gene3D G3DSA:1.10.10.60 8 75 6.4E-26 T 13-10-2018 Astex_2441 8a93d9b2fdd652057ab89690c7104e85 205 SUPERFAMILY SSF48498 91 204 7.87E-25 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily Astex_2441 8a93d9b2fdd652057ab89690c7104e85 205 Gene3D G3DSA:1.10.357.10 85 205 2.8E-28 T 13-10-2018 Astex_2441 8a93d9b2fdd652057ab89690c7104e85 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 68 2.8E-13 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Astex_2441 8a93d9b2fdd652057ab89690c7104e85 205 SUPERFAMILY SSF46689 9 86 4.05E-16 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Astex_2693 9d05deaa8b3c1b9f00bbb617e4bcb373 195 Gene3D G3DSA:1.10.1740.10 11 95 1.1E-20 T 13-10-2018 Astex_2693 9d05deaa8b3c1b9f00bbb617e4bcb373 195 Pfam PF04542 Sigma-70 region 2 33 99 1.4E-11 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 Astex_2693 9d05deaa8b3c1b9f00bbb617e4bcb373 195 Pfam PF08281 Sigma-70, region 4 128 179 1.6E-9 T 13-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Astex_2693 9d05deaa8b3c1b9f00bbb617e4bcb373 195 SUPERFAMILY SSF88659 127 183 1.85E-11 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Astex_2693 9d05deaa8b3c1b9f00bbb617e4bcb373 195 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 28 182 2.4E-19 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 Astex_2693 9d05deaa8b3c1b9f00bbb617e4bcb373 195 SUPERFAMILY SSF88946 13 109 3.92E-18 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 Astex_2693 9d05deaa8b3c1b9f00bbb617e4bcb373 195 Gene3D G3DSA:1.10.10.10 96 186 6.7E-17 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1137 4ae07499f6ab7e28bb590ff92b605299 409 Pfam PF01743 Poly A polymerase head domain 31 153 1.4E-23 T 13-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 Astex_1137 4ae07499f6ab7e28bb590ff92b605299 409 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 185 239 3.8E-7 T 13-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 Astex_1137 4ae07499f6ab7e28bb590ff92b605299 409 SUPERFAMILY SSF81891 151 389 4.19E-40 T 13-10-2018 Astex_1137 4ae07499f6ab7e28bb590ff92b605299 409 SUPERFAMILY SSF81301 14 147 1.2E-29 T 13-10-2018 Astex_1137 4ae07499f6ab7e28bb590ff92b605299 409 Gene3D G3DSA:3.30.460.10 7 149 2.7E-34 T 13-10-2018 Astex_1137 4ae07499f6ab7e28bb590ff92b605299 409 Gene3D G3DSA:1.10.3090.10 151 310 5.2E-25 T 13-10-2018 Astex_3639 595dd0a59fd1f2d14d0905f90dfd0b47 693 SUPERFAMILY SSF58104 408 686 2.62E-59 T 13-10-2018 Astex_3639 595dd0a59fd1f2d14d0905f90dfd0b47 693 Gene3D G3DSA:1.20.1480.50 310 396 5.3E-13 T 13-10-2018 Astex_3639 595dd0a59fd1f2d14d0905f90dfd0b47 693 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 499 656 1.8E-29 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_3639 595dd0a59fd1f2d14d0905f90dfd0b47 693 Gene3D G3DSA:3.30.450.20 62 209 1.1E-63 T 13-10-2018 Astex_3639 595dd0a59fd1f2d14d0905f90dfd0b47 693 Gene3D G3DSA:1.10.287.950 397 693 4.6E-52 T 13-10-2018 Astex_3639 595dd0a59fd1f2d14d0905f90dfd0b47 693 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 560 589 9.4E-5 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_3639 595dd0a59fd1f2d14d0905f90dfd0b47 693 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 461 490 9.4E-5 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_3639 595dd0a59fd1f2d14d0905f90dfd0b47 693 Pfam PF02743 Cache domain 39 303 4.2E-23 T 13-10-2018 IPR033479 Double Cache domain 1 Astex_3639 595dd0a59fd1f2d14d0905f90dfd0b47 693 SUPERFAMILY SSF158472 342 391 3.92E-6 T 13-10-2018 Astex_3639 595dd0a59fd1f2d14d0905f90dfd0b47 693 SMART SM00283 433 687 1.3E-40 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_3639 595dd0a59fd1f2d14d0905f90dfd0b47 693 SMART SM00304 342 395 6.4E-5 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Astex_3639 595dd0a59fd1f2d14d0905f90dfd0b47 693 Gene3D G3DSA:3.30.450.20 54 309 1.1E-63 T 13-10-2018 Astex_0088 cf275de551d30cd382ca7cadd386837c 219 Gene3D G3DSA:2.40.160.20 32 219 9.3E-49 T 13-10-2018 Astex_0088 cf275de551d30cd382ca7cadd386837c 219 SUPERFAMILY SSF56925 35 219 2.88E-26 T 13-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel Astex_0088 cf275de551d30cd382ca7cadd386837c 219 Pfam PF03922 OmpW family 34 219 2.0E-57 T 13-10-2018 IPR005618 Outer membrane protein, OmpW GO:0019867 Astex_3480 d68c0caa689bda85c1909907f8868c02 184 SUPERFAMILY SSF52141 16 174 6.1E-31 T 13-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Astex_3480 d68c0caa689bda85c1909907f8868c02 184 Gene3D G3DSA:3.40.470.10 18 183 1.1E-49 T 13-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Astex_3480 d68c0caa689bda85c1909907f8868c02 184 Pfam PF03167 Uracil DNA glycosylase superfamily 18 172 6.0E-18 T 13-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Astex_3480 d68c0caa689bda85c1909907f8868c02 184 SMART SM00986 17 172 8.8E-6 T 13-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Astex_3480 d68c0caa689bda85c1909907f8868c02 184 SMART SM00987 17 172 8.8E-6 T 13-10-2018 Astex_2709 d0b54dbaca6aa945d3f882662badc64a 178 PIRSF PIRSF008502 1 177 7.0E-45 T 13-10-2018 IPR012545 Protein of unknown function DUF1697 Astex_2709 d0b54dbaca6aa945d3f882662badc64a 178 SUPERFAMILY SSF160379 2 175 3.01E-44 T 13-10-2018 Astex_2709 d0b54dbaca6aa945d3f882662badc64a 178 Pfam PF08002 Protein of unknown function (DUF1697) 2 137 1.2E-35 T 13-10-2018 IPR012545 Protein of unknown function DUF1697 Astex_2709 d0b54dbaca6aa945d3f882662badc64a 178 Gene3D G3DSA:3.30.70.1280 1 88 2.1E-25 T 13-10-2018 Astex_0354 a9c859a7ccaf553bea9099dc0e05fc5b 192 SUPERFAMILY SSF54001 97 154 1.28E-5 T 13-10-2018 IPR038765 Papain-like cysteine peptidase superfamily Astex_0354 a9c859a7ccaf553bea9099dc0e05fc5b 192 Gene3D G3DSA:3.90.1720.10 41 174 3.4E-6 T 13-10-2018 Astex_0354 a9c859a7ccaf553bea9099dc0e05fc5b 192 TIGRFAM TIGR02594 TIGR02594: TIGR02594 family protein 18 164 1.5E-24 T 13-10-2018 IPR013423 Conserved hypothetical protein CHP02594 Astex_3407 3bb07e8671235fd8423f79b59eb601ba 564 Gene3D G3DSA:3.30.450.20 63 183 2.3E-33 T 13-10-2018 Astex_3407 3bb07e8671235fd8423f79b59eb601ba 564 SUPERFAMILY SSF55874 406 560 1.09E-33 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_3407 3bb07e8671235fd8423f79b59eb601ba 564 Pfam PF00512 His Kinase A (phospho-acceptor) domain 345 412 1.8E-10 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_3407 3bb07e8671235fd8423f79b59eb601ba 564 Gene3D G3DSA:3.30.565.10 408 561 8.9E-35 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_3407 3bb07e8671235fd8423f79b59eb601ba 564 SMART SM00387 457 564 1.0E-26 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_3407 3bb07e8671235fd8423f79b59eb601ba 564 Gene3D G3DSA:1.10.287.130 321 407 2.0E-18 T 13-10-2018 Astex_3407 3bb07e8671235fd8423f79b59eb601ba 564 PRINTS PR00344 Bacterial sensor protein C-terminal signature 514 524 2.3E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_3407 3bb07e8671235fd8423f79b59eb601ba 564 PRINTS PR00344 Bacterial sensor protein C-terminal signature 548 561 2.3E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_3407 3bb07e8671235fd8423f79b59eb601ba 564 PRINTS PR00344 Bacterial sensor protein C-terminal signature 496 510 2.3E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_3407 3bb07e8671235fd8423f79b59eb601ba 564 PRINTS PR00344 Bacterial sensor protein C-terminal signature 525 543 2.3E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_3407 3bb07e8671235fd8423f79b59eb601ba 564 SUPERFAMILY SSF103190 98 194 2.33E-16 T 13-10-2018 IPR029151 Periplasmic sensor-like domain superfamily Astex_3407 3bb07e8671235fd8423f79b59eb601ba 564 PIRSF PIRSF036431 5 236 4.9E-58 T 13-10-2018 IPR017055 Signal transduction histidine kinase, DctB (C4-dicarboxylate transport system regulator) Astex_3407 3bb07e8671235fd8423f79b59eb601ba 564 PIRSF PIRSF036431 228 564 8.1E-105 T 13-10-2018 IPR017055 Signal transduction histidine kinase, DctB (C4-dicarboxylate transport system regulator) Astex_3407 3bb07e8671235fd8423f79b59eb601ba 564 SMART SM00388 345 415 5.8E-9 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_3407 3bb07e8671235fd8423f79b59eb601ba 564 SUPERFAMILY SSF47384 336 414 5.1E-9 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Astex_3407 3bb07e8671235fd8423f79b59eb601ba 564 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 460 560 3.5E-16 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_0445 a3a175d73c5fb9e77acf71c3ced89f44 892 ProSitePatterns PS00450 Aconitase family signature 1. 426 442 - T 13-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 Astex_0445 a3a175d73c5fb9e77acf71c3ced89f44 892 Gene3D G3DSA:3.20.19.10 653 891 4.5E-101 T 13-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 Astex_0445 a3a175d73c5fb9e77acf71c3ced89f44 892 Pfam PF00330 Aconitase family (aconitate hydratase) 76 561 1.0E-184 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Astex_0445 a3a175d73c5fb9e77acf71c3ced89f44 892 Gene3D G3DSA:3.30.499.10 374 589 3.1E-96 T 13-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 Astex_0445 a3a175d73c5fb9e77acf71c3ced89f44 892 ProSitePatterns PS01244 Aconitase family signature 2. 492 505 - T 13-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 Astex_0445 a3a175d73c5fb9e77acf71c3ced89f44 892 Gene3D G3DSA:1.10.1440.20 590 651 7.8E-20 T 13-10-2018 Astex_0445 a3a175d73c5fb9e77acf71c3ced89f44 892 Pfam PF00694 Aconitase C-terminal domain 694 817 5.2E-44 T 13-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 Astex_0445 a3a175d73c5fb9e77acf71c3ced89f44 892 SUPERFAMILY SSF53732 3 625 1.1E-225 T 13-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 Astex_0445 a3a175d73c5fb9e77acf71c3ced89f44 892 Gene3D G3DSA:3.30.499.20 6 373 1.0E-158 T 13-10-2018 Astex_0445 a3a175d73c5fb9e77acf71c3ced89f44 892 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 18 889 0.0 T 13-10-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 Astex_0445 a3a175d73c5fb9e77acf71c3ced89f44 892 SUPERFAMILY SSF52016 629 889 1.63E-86 T 13-10-2018 Astex_0445 a3a175d73c5fb9e77acf71c3ced89f44 892 PRINTS PR00415 Aconitase family signature 204 217 8.4E-43 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Astex_0445 a3a175d73c5fb9e77acf71c3ced89f44 892 PRINTS PR00415 Aconitase family signature 171 179 8.4E-43 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Astex_0445 a3a175d73c5fb9e77acf71c3ced89f44 892 PRINTS PR00415 Aconitase family signature 430 441 8.4E-43 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Astex_0445 a3a175d73c5fb9e77acf71c3ced89f44 892 PRINTS PR00415 Aconitase family signature 147 160 8.4E-43 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Astex_0445 a3a175d73c5fb9e77acf71c3ced89f44 892 PRINTS PR00415 Aconitase family signature 492 505 8.4E-43 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Astex_0445 a3a175d73c5fb9e77acf71c3ced89f44 892 PRINTS PR00415 Aconitase family signature 218 233 8.4E-43 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Astex_0445 a3a175d73c5fb9e77acf71c3ced89f44 892 PRINTS PR00415 Aconitase family signature 280 293 8.4E-43 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Astex_0445 a3a175d73c5fb9e77acf71c3ced89f44 892 PRINTS PR00415 Aconitase family signature 373 387 8.4E-43 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Astex_0445 a3a175d73c5fb9e77acf71c3ced89f44 892 PRINTS PR00415 Aconitase family signature 294 307 8.4E-43 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 Astex_1958 f194e637d8f9aab3e08850dc11944954 867 Gene3D G3DSA:1.10.390.10 283 446 2.6E-57 T 13-10-2018 IPR027268 Peptidase M4/M1, CTD superfamily Astex_1958 f194e637d8f9aab3e08850dc11944954 867 Gene3D G3DSA:1.25.50.10 552 866 1.9E-103 T 13-10-2018 IPR037144 Peptidase M1, alanyl aminopeptidase, C-terminal domain superfamily Astex_1958 f194e637d8f9aab3e08850dc11944954 867 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 261 271 3.5E-8 T 13-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Astex_1958 f194e637d8f9aab3e08850dc11944954 867 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 179 194 3.5E-8 T 13-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Astex_1958 f194e637d8f9aab3e08850dc11944954 867 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 316 328 3.5E-8 T 13-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Astex_1958 f194e637d8f9aab3e08850dc11944954 867 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 297 312 3.5E-8 T 13-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Astex_1958 f194e637d8f9aab3e08850dc11944954 867 Pfam PF17432 Domain of unknown function (DUF3458_C) ARM repeats 557 866 1.2E-106 T 13-10-2018 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal Astex_1958 f194e637d8f9aab3e08850dc11944954 867 Pfam PF01433 Peptidase family M1 domain 211 436 1.9E-52 T 13-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Astex_1958 f194e637d8f9aab3e08850dc11944954 867 Gene3D G3DSA:1.10.1740.60 198 282 7.7E-38 T 13-10-2018 Astex_1958 f194e637d8f9aab3e08850dc11944954 867 TIGRFAM TIGR02414 pepN_proteo: aminopeptidase N 14 864 0.0 T 13-10-2018 IPR012779 Peptidase M1, alanyl aminopeptidase GO:0008270 Astex_1958 f194e637d8f9aab3e08850dc11944954 867 Gene3D G3DSA:2.60.40.1840 447 548 1.4E-25 T 13-10-2018 IPR038438 Alanyl aminopeptidase, Ig-like domain superfamily Astex_1958 f194e637d8f9aab3e08850dc11944954 867 SUPERFAMILY SSF63737 8 196 1.27E-38 T 13-10-2018 Astex_1958 f194e637d8f9aab3e08850dc11944954 867 Gene3D G3DSA:2.60.40.1730 17 197 1.2E-63 T 13-10-2018 Astex_1958 f194e637d8f9aab3e08850dc11944954 867 SUPERFAMILY SSF55486 207 453 2.01E-70 T 13-10-2018 Astex_1958 f194e637d8f9aab3e08850dc11944954 867 Pfam PF11940 Domain of unknown function (DUF3458) Ig-like fold 447 547 4.8E-25 T 13-10-2018 IPR035414 Peptidase M1, alanyl aminopeptidase, Ig-like fold Astex_0424 bc2e6b425cce116dca52363236af49a3 304 SMART SM00858 48 153 0.002 T 13-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 Astex_0424 bc2e6b425cce116dca52363236af49a3 304 Pfam PF08666 SAF domain 49 149 9.4E-6 T 13-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 Astex_0424 bc2e6b425cce116dca52363236af49a3 304 TIGRFAM TIGR03177 pilus_cpaB: Flp pilus assembly protein CpaB 7 283 6.1E-58 T 13-10-2018 IPR017592 Pilus assembly, Flp-type CpaB Astex_0424 bc2e6b425cce116dca52363236af49a3 304 Pfam PF16976 Flp pilus assembly protein RcpC/CpaB 159 266 3.0E-30 T 13-10-2018 IPR031571 Flp pilus assembly protein RcpC/CpaB domain Astex_3802 eba2cf5ad352f3b6d91e3e24922f6bd9 135 SUPERFAMILY SSF52091 42 130 1.02E-5 T 13-10-2018 IPR036513 STAS domain superfamily Astex_0782 312aab96dba5da549b5bb96f9b8a884d 407 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 154 170 - T 13-10-2018 IPR018201 Beta-ketoacyl synthase, active site Astex_0782 312aab96dba5da549b5bb96f9b8a884d 407 SUPERFAMILY SSF53901 1 253 2.08E-58 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 Astex_0782 312aab96dba5da549b5bb96f9b8a884d 407 Gene3D G3DSA:3.40.47.10 1 254 1.0E-58 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 Astex_0782 312aab96dba5da549b5bb96f9b8a884d 407 SMART SM00825 Beta-ketoacyl synthase 4 407 1.9E-13 T 13-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain Astex_0782 312aab96dba5da549b5bb96f9b8a884d 407 SUPERFAMILY SSF53901 215 404 1.44E-60 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 Astex_0782 312aab96dba5da549b5bb96f9b8a884d 407 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 254 362 2.0E-31 T 13-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal Astex_0782 312aab96dba5da549b5bb96f9b8a884d 407 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1 246 1.1E-40 T 13-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal Astex_0782 312aab96dba5da549b5bb96f9b8a884d 407 Gene3D G3DSA:3.40.47.10 260 406 2.2E-45 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 Astex_2874 faa969763e7d4179ded9eb1cc70498c7 269 Gene3D G3DSA:3.60.15.10 2 267 1.3E-57 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Astex_2874 faa969763e7d4179ded9eb1cc70498c7 269 Pfam PF12706 Beta-lactamase superfamily domain 55 237 1.5E-27 T 13-10-2018 IPR001279 Metallo-beta-lactamase Astex_2874 faa969763e7d4179ded9eb1cc70498c7 269 SUPERFAMILY SSF56281 7 266 1.09E-32 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Astex_2939 962b335a0edc7c68becf767accd88353 379 SUPERFAMILY SSF142695 221 378 5.36E-31 T 13-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 Astex_2939 962b335a0edc7c68becf767accd88353 379 Gene3D G3DSA:3.90.870.10 10 222 4.7E-84 T 13-10-2018 Astex_2939 962b335a0edc7c68becf767accd88353 379 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 23 214 2.6E-78 T 13-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Astex_2939 962b335a0edc7c68becf767accd88353 379 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 17 219 37.343 T 13-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Astex_2939 962b335a0edc7c68becf767accd88353 379 SUPERFAMILY SSF55821 17 219 1.49E-82 T 13-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily Astex_2939 962b335a0edc7c68becf767accd88353 379 PIRSF PIRSF001259 18 379 9.3E-109 T 13-10-2018 Astex_2939 962b335a0edc7c68becf767accd88353 379 Pfam PF00925 GTP cyclohydrolase II 226 374 2.9E-21 T 13-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 Astex_2939 962b335a0edc7c68becf767accd88353 379 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 20 215 2.0E-68 T 13-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 Astex_2939 962b335a0edc7c68becf767accd88353 379 Gene3D G3DSA:3.40.50.10990 223 379 1.4E-19 T 13-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 Astex_0764 4587213d85e2a656052e6cce48bf79f6 432 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 5 432 1.8E-184 T 13-10-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 Astex_0764 4587213d85e2a656052e6cce48bf79f6 432 SMART SM00382 49 321 4.0E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_0764 4587213d85e2a656052e6cce48bf79f6 432 SUPERFAMILY SSF52540 6 429 1.43E-82 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0764 4587213d85e2a656052e6cce48bf79f6 432 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 324 394 1.7E-6 T 13-10-2018 IPR019489 Clp ATPase, C-terminal Astex_0764 4587213d85e2a656052e6cce48bf79f6 432 Gene3D G3DSA:1.10.8.60 324 429 9.1E-38 T 13-10-2018 Astex_0764 4587213d85e2a656052e6cce48bf79f6 432 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 53 114 7.5E-7 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Astex_0764 4587213d85e2a656052e6cce48bf79f6 432 Pfam PF07724 AAA domain (Cdc48 subfamily) 176 318 3.7E-39 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Astex_0764 4587213d85e2a656052e6cce48bf79f6 432 Gene3D G3DSA:3.40.50.300 6 321 3.1E-105 T 13-10-2018 Astex_0764 4587213d85e2a656052e6cce48bf79f6 432 Gene3D G3DSA:1.10.8.10 110 232 3.1E-105 T 13-10-2018 Astex_0764 4587213d85e2a656052e6cce48bf79f6 432 SMART SM01086 324 418 4.3E-20 T 13-10-2018 IPR019489 Clp ATPase, C-terminal Astex_0764 4587213d85e2a656052e6cce48bf79f6 432 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 1 432 40.996 T 13-10-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 Astex_3213 9c9a96511686e737849d09955802122a 521 Pfam PF04820 Tryptophan halogenase 22 470 2.3E-161 T 13-10-2018 IPR006905 Flavin-dependent halogenase Astex_3213 9c9a96511686e737849d09955802122a 521 SUPERFAMILY SSF51905 21 419 5.56E-29 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_3213 9c9a96511686e737849d09955802122a 521 PIRSF PIRSF011396 15 511 6.5E-167 T 13-10-2018 IPR033856 Flavin-dependent tryptophan halogenase Astex_3213 9c9a96511686e737849d09955802122a 521 Gene3D G3DSA:3.50.50.60 17 506 2.9E-168 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_3612 de60cf9a7da4fccd7bd0d4ed3e83fac2 526 Pfam PF06964 Alpha-L-arabinofuranosidase C-terminal domain 329 519 6.1E-38 T 13-10-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 Astex_3612 de60cf9a7da4fccd7bd0d4ed3e83fac2 526 SMART SM00813 329 519 3.2E-74 T 13-10-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 Astex_3612 de60cf9a7da4fccd7bd0d4ed3e83fac2 526 SUPERFAMILY SSF51445 49 410 2.04E-88 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_3612 de60cf9a7da4fccd7bd0d4ed3e83fac2 526 SUPERFAMILY SSF51011 397 526 6.11E-23 T 13-10-2018 Astex_3612 de60cf9a7da4fccd7bd0d4ed3e83fac2 526 Gene3D G3DSA:3.20.20.80 50 411 1.2E-173 T 13-10-2018 Astex_3612 de60cf9a7da4fccd7bd0d4ed3e83fac2 526 Gene3D G3DSA:2.60.40.1180 48 523 1.2E-173 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta Astex_2237 737c27ea46f09ea2f7bf717200b36800 413 Gene3D G3DSA:1.10.1200.160 353 383 6.3E-46 T 13-10-2018 Astex_2237 737c27ea46f09ea2f7bf717200b36800 413 Gene3D G3DSA:2.40.128.260 234 402 6.3E-46 T 13-10-2018 Astex_2237 737c27ea46f09ea2f7bf717200b36800 413 Pfam PF03743 Bacterial conjugation TrbI-like protein 231 404 9.2E-47 T 13-10-2018 IPR005498 Type IV secretion system, VirB10 / TraB / TrbI Astex_1816 7c538d2479e59269308057c3f2e4f503 208 Gene3D G3DSA:1.20.1440.20 18 198 2.7E-58 T 13-10-2018 IPR023353 LemA-like domain superfamily Astex_1816 7c538d2479e59269308057c3f2e4f503 208 SUPERFAMILY SSF140478 30 186 9.55E-49 T 13-10-2018 IPR023353 LemA-like domain superfamily Astex_1816 7c538d2479e59269308057c3f2e4f503 208 Pfam PF04011 LemA family 12 198 2.3E-60 T 13-10-2018 IPR007156 LemA Astex_3231 364804b9d22013d22dbb8741414f3765 269 Pfam PF02153 Prephenate dehydrogenase 45 264 5.7E-26 T 13-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 Astex_3231 364804b9d22013d22dbb8741414f3765 269 SUPERFAMILY SSF48179 178 267 2.89E-9 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Astex_3231 364804b9d22013d22dbb8741414f3765 269 SUPERFAMILY SSF51735 20 164 7.33E-25 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_3231 364804b9d22013d22dbb8741414f3765 269 Gene3D G3DSA:3.40.50.720 19 184 3.4E-28 T 13-10-2018 Astex_1096 c0f094df84226561a0e06526bb3f0c6f 113 SUPERFAMILY SSF54862 1 81 6.85E-22 T 13-10-2018 Astex_1096 c0f094df84226561a0e06526bb3f0c6f 113 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Astex_1096 c0f094df84226561a0e06526bb3f0c6f 113 PRINTS PR00354 7Fe ferredoxin signature 9 19 2.8E-18 T 13-10-2018 IPR000813 7Fe ferredoxin GO:0009055 Astex_1096 c0f094df84226561a0e06526bb3f0c6f 113 PRINTS PR00354 7Fe ferredoxin signature 35 52 2.8E-18 T 13-10-2018 IPR000813 7Fe ferredoxin GO:0009055 Astex_1096 c0f094df84226561a0e06526bb3f0c6f 113 PRINTS PR00354 7Fe ferredoxin signature 19 29 2.8E-18 T 13-10-2018 IPR000813 7Fe ferredoxin GO:0009055 Astex_1096 c0f094df84226561a0e06526bb3f0c6f 113 Pfam PF11953 Domain of unknown function (DUF3470) 66 106 4.3E-14 T 13-10-2018 IPR022569 Ferredoxin, C-terminal Astex_1096 c0f094df84226561a0e06526bb3f0c6f 113 Pfam PF00037 4Fe-4S binding domain 34 56 2.2E-8 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Astex_1096 c0f094df84226561a0e06526bb3f0c6f 113 Gene3D G3DSA:3.30.70.20 2 104 1.3E-29 T 13-10-2018 Astex_0063 5e59a4203d752aa27e4dc338ebee8dea 670 SUPERFAMILY SSF141868 418 661 1.01E-78 T 13-10-2018 IPR035919 EAL domain superfamily Astex_0063 5e59a4203d752aa27e4dc338ebee8dea 670 Gene3D G3DSA:3.30.70.270 236 415 3.3E-43 T 13-10-2018 Astex_0063 5e59a4203d752aa27e4dc338ebee8dea 670 SUPERFAMILY SSF55073 242 404 4.08E-38 T 13-10-2018 IPR029787 Nucleotide cyclase Astex_0063 5e59a4203d752aa27e4dc338ebee8dea 670 Pfam PF00990 Diguanylate cyclase, GGDEF domain 237 396 8.3E-36 T 13-10-2018 IPR000160 GGDEF domain Astex_0063 5e59a4203d752aa27e4dc338ebee8dea 670 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 237 400 6.4E-33 T 13-10-2018 IPR000160 GGDEF domain Astex_0063 5e59a4203d752aa27e4dc338ebee8dea 670 Gene3D G3DSA:3.20.20.450 416 669 2.2E-83 T 13-10-2018 IPR035919 EAL domain superfamily Astex_0063 5e59a4203d752aa27e4dc338ebee8dea 670 Pfam PF00563 EAL domain 426 648 3.5E-70 T 13-10-2018 IPR001633 EAL domain Astex_0063 5e59a4203d752aa27e4dc338ebee8dea 670 SMART SM00267 226 402 1.3E-45 T 13-10-2018 IPR000160 GGDEF domain Astex_0063 5e59a4203d752aa27e4dc338ebee8dea 670 SMART SM00052 412 653 3.5E-84 T 13-10-2018 IPR001633 EAL domain Astex_3302 dc690113e4e6a2adedf77fd17315223b 150 SUPERFAMILY SSF54909 72 148 2.36E-14 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel Astex_3302 dc690113e4e6a2adedf77fd17315223b 150 Pfam PF01037 Lrp/AsnC ligand binding domain 86 145 4.9E-13 T 13-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Astex_3302 dc690113e4e6a2adedf77fd17315223b 150 Gene3D G3DSA:1.10.10.10 2 61 1.4E-16 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_3302 dc690113e4e6a2adedf77fd17315223b 150 SUPERFAMILY SSF46785 10 64 2.82E-10 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_3302 dc690113e4e6a2adedf77fd17315223b 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 10 26 9.0E-8 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 Astex_3302 dc690113e4e6a2adedf77fd17315223b 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 26 37 9.0E-8 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 Astex_3302 dc690113e4e6a2adedf77fd17315223b 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 37 56 9.0E-8 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 Astex_3302 dc690113e4e6a2adedf77fd17315223b 150 Pfam PF13404 AsnC-type helix-turn-helix domain 10 51 5.9E-11 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 Astex_3302 dc690113e4e6a2adedf77fd17315223b 150 SMART SM00344 10 116 2.4E-13 T 13-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 Astex_3302 dc690113e4e6a2adedf77fd17315223b 150 Gene3D G3DSA:3.30.70.920 74 147 7.8E-16 T 13-10-2018 Astex_0036 a08978ed5a5dca2c98c9a1afd3e10451 760 Pfam PF01515 Phosphate acetyl/butaryl transferase 433 751 1.5E-78 T 13-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 Astex_0036 a08978ed5a5dca2c98c9a1afd3e10451 760 Gene3D G3DSA:3.40.50.10950 449 751 6.3E-79 T 13-10-2018 Astex_0036 a08978ed5a5dca2c98c9a1afd3e10451 760 Gene3D G3DSA:3.40.50.720 165 448 4.8E-82 T 13-10-2018 Astex_0036 a08978ed5a5dca2c98c9a1afd3e10451 760 Gene3D G3DSA:3.40.50.10750 576 727 6.3E-79 T 13-10-2018 Astex_0036 a08978ed5a5dca2c98c9a1afd3e10451 760 SMART SM01274 22 155 1.9E-77 T 13-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 Astex_0036 a08978ed5a5dca2c98c9a1afd3e10451 760 SMART SM00919 167 404 8.6E-135 T 13-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 Astex_0036 a08978ed5a5dca2c98c9a1afd3e10451 760 SUPERFAMILY SSF51735 167 444 5.98E-84 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_0036 a08978ed5a5dca2c98c9a1afd3e10451 760 Gene3D G3DSA:3.40.50.10380 3 164 4.1E-65 T 13-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 Astex_0036 a08978ed5a5dca2c98c9a1afd3e10451 760 PIRSF PIRSF036684 3 759 0.0 T 13-10-2018 IPR012188 NAD(P)-dependent malic enzyme GO:0004470|GO:0006108|GO:0046872 KEGG: 00620+1.1.1.40|KEGG: 00710+1.1.1.40|MetaCyc: PWY-241|MetaCyc: PWY-7117 Astex_0036 a08978ed5a5dca2c98c9a1afd3e10451 760 SUPERFAMILY SSF53659 434 754 1.03E-78 T 13-10-2018 Astex_0036 a08978ed5a5dca2c98c9a1afd3e10451 760 ProSitePatterns PS00331 Malic enzymes signature. 163 179 - T 13-10-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 Astex_0036 a08978ed5a5dca2c98c9a1afd3e10451 760 Pfam PF00390 Malic enzyme, N-terminal domain 25 154 2.6E-25 T 13-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 Astex_0036 a08978ed5a5dca2c98c9a1afd3e10451 760 Pfam PF03949 Malic enzyme, NAD binding domain 169 364 2.9E-23 T 13-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 Astex_0036 a08978ed5a5dca2c98c9a1afd3e10451 760 SUPERFAMILY SSF53223 13 165 3.38E-50 T 13-10-2018 Astex_0181 f5c6842b0274e05bafebd41d43b7aa39 292 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 13 291 2.0E-104 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 Astex_0181 f5c6842b0274e05bafebd41d43b7aa39 292 Gene3D G3DSA:3.40.50.170 96 292 2.4E-74 T 13-10-2018 Astex_0181 f5c6842b0274e05bafebd41d43b7aa39 292 SUPERFAMILY SSF55021 11 94 3.04E-13 T 13-10-2018 Astex_0181 f5c6842b0274e05bafebd41d43b7aa39 292 Gene3D G3DSA:3.30.70.260 7 94 2.3E-22 T 13-10-2018 Astex_0181 f5c6842b0274e05bafebd41d43b7aa39 292 SUPERFAMILY SSF53328 97 292 5.63E-65 T 13-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Astex_0181 f5c6842b0274e05bafebd41d43b7aa39 292 Pfam PF00551 Formyl transferase 97 273 9.9E-38 T 13-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Astex_0181 f5c6842b0274e05bafebd41d43b7aa39 292 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 9 291 46.489 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 Astex_0181 f5c6842b0274e05bafebd41d43b7aa39 292 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 14 40 8.5E-50 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 Astex_0181 f5c6842b0274e05bafebd41d43b7aa39 292 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 243 265 8.5E-50 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 Astex_0181 f5c6842b0274e05bafebd41d43b7aa39 292 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 97 119 8.5E-50 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 Astex_0181 f5c6842b0274e05bafebd41d43b7aa39 292 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 46 58 8.5E-50 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 Astex_0181 f5c6842b0274e05bafebd41d43b7aa39 292 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 265 290 8.5E-50 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 Astex_0181 f5c6842b0274e05bafebd41d43b7aa39 292 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 119 146 8.5E-50 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 Astex_0181 f5c6842b0274e05bafebd41d43b7aa39 292 PIRSF PIRSF036480 9 292 3.8E-109 T 13-10-2018 Astex_2745 080bb960db5a867844abad5cbebe030d 142 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 142 29.792 T 13-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 Astex_2745 080bb960db5a867844abad5cbebe030d 142 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 67 3.0E-28 T 13-10-2018 IPR020784 Ribosomal protein L11, N-terminal Astex_2745 080bb960db5a867844abad5cbebe030d 142 ProSitePatterns PS00359 Ribosomal protein L11 signature. 127 142 - T 13-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_2745 080bb960db5a867844abad5cbebe030d 142 Pfam PF00298 Ribosomal protein L11, RNA binding domain 72 140 1.7E-21 T 13-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 Astex_2745 080bb960db5a867844abad5cbebe030d 142 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 142 1.5E-64 T 13-10-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_2745 080bb960db5a867844abad5cbebe030d 142 Gene3D G3DSA:3.30.1550.10 2 72 1.6E-34 T 13-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily Astex_2745 080bb960db5a867844abad5cbebe030d 142 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 74 1.0E-16 T 13-10-2018 Astex_2745 080bb960db5a867844abad5cbebe030d 142 SUPERFAMILY SSF54747 3 73 1.2E-29 T 13-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily Astex_2745 080bb960db5a867844abad5cbebe030d 142 Gene3D G3DSA:1.10.10.2720 73 142 2.2E-24 T 13-10-2018 Astex_2745 080bb960db5a867844abad5cbebe030d 142 SMART SM00649 9 141 4.9E-80 T 13-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 Astex_2745 080bb960db5a867844abad5cbebe030d 142 SUPERFAMILY SSF46906 68 140 8.77E-24 T 13-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily Astex_1673 8caa23a79e40a3c9ccec832a354e92a4 452 Pfam PF14450 Cell division protein FtsA 235 404 6.8E-20 T 13-10-2018 Astex_1673 8caa23a79e40a3c9ccec832a354e92a4 452 Gene3D G3DSA:3.30.420.40 36 401 4.4E-92 T 13-10-2018 Astex_1673 8caa23a79e40a3c9ccec832a354e92a4 452 Pfam PF02491 SHS2 domain inserted in FTSA 112 189 4.1E-14 T 13-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 Astex_1673 8caa23a79e40a3c9ccec832a354e92a4 452 SUPERFAMILY SSF53067 33 224 8.43E-38 T 13-10-2018 Astex_1673 8caa23a79e40a3c9ccec832a354e92a4 452 Gene3D G3DSA:3.90.640.10 262 330 4.4E-92 T 13-10-2018 Astex_1673 8caa23a79e40a3c9ccec832a354e92a4 452 PIRSF PIRSF003101 18 452 5.1E-113 T 13-10-2018 IPR020823 Cell division protein FtsA Astex_1673 8caa23a79e40a3c9ccec832a354e92a4 452 Gene3D G3DSA:3.30.1490.110 112 196 4.4E-92 T 13-10-2018 Astex_1673 8caa23a79e40a3c9ccec832a354e92a4 452 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 33 407 7.2E-96 T 13-10-2018 IPR020823 Cell division protein FtsA Astex_1673 8caa23a79e40a3c9ccec832a354e92a4 452 Gene3D G3DSA:3.30.420.40 224 382 4.4E-92 T 13-10-2018 Astex_1673 8caa23a79e40a3c9ccec832a354e92a4 452 Hamap MF_02033 Cell division protein FtsA [ftsA]. 29 452 25.025 T 13-10-2018 IPR020823 Cell division protein FtsA Astex_1673 8caa23a79e40a3c9ccec832a354e92a4 452 SMART SM00842 33 223 2.1E-58 T 13-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 Astex_1673 8caa23a79e40a3c9ccec832a354e92a4 452 SUPERFAMILY SSF53067 226 407 1.66E-36 T 13-10-2018 Astex_3245 688079d1160d71adae15a4a694bb392d 269 Hamap MF_00472 Ubiquinone biosynthesis O-methyltransferase [ubiG]. 32 267 39.737 T 13-10-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 Astex_3245 688079d1160d71adae15a4a694bb392d 269 SUPERFAMILY SSF53335 28 247 1.52E-43 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Astex_3245 688079d1160d71adae15a4a694bb392d 269 Pfam PF13489 Methyltransferase domain 81 234 1.8E-23 T 13-10-2018 Astex_3245 688079d1160d71adae15a4a694bb392d 269 TIGRFAM TIGR01983 UbiG: 3-demethylubiquinone-9 3-O-methyltransferase 33 261 3.6E-86 T 13-10-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 Astex_3245 688079d1160d71adae15a4a694bb392d 269 Gene3D G3DSA:3.40.50.150 32 267 1.5E-72 T 13-10-2018 Astex_0476 745f9a5cb9d1a594abf5bea73fadde54 323 SMART SM00829 11 321 3.1E-34 T 13-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Astex_0476 745f9a5cb9d1a594abf5bea73fadde54 323 SUPERFAMILY SSF50129 3 143 1.45E-38 T 13-10-2018 IPR011032 GroES-like superfamily Astex_0476 745f9a5cb9d1a594abf5bea73fadde54 323 SUPERFAMILY SSF51735 110 273 2.29E-50 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_0476 745f9a5cb9d1a594abf5bea73fadde54 323 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 139 160 - T 13-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 Astex_0476 745f9a5cb9d1a594abf5bea73fadde54 323 Pfam PF00107 Zinc-binding dehydrogenase 150 255 5.4E-29 T 13-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Astex_0476 745f9a5cb9d1a594abf5bea73fadde54 323 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 88 1.4E-10 T 13-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Astex_0476 745f9a5cb9d1a594abf5bea73fadde54 323 Gene3D G3DSA:3.90.180.10 11 317 1.3E-114 T 13-10-2018 Astex_0476 745f9a5cb9d1a594abf5bea73fadde54 323 Gene3D G3DSA:3.40.50.720 122 267 1.3E-114 T 13-10-2018 Astex_2313 d6cfe665f388904d44d999e0d9c61e98 415 Gene3D G3DSA:3.30.9.50 79 280 2.0E-93 T 13-10-2018 Astex_2313 d6cfe665f388904d44d999e0d9c61e98 415 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 305 318 - T 13-10-2018 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 Astex_2313 d6cfe665f388904d44d999e0d9c61e98 415 Pfam PF01494 FAD binding domain 5 331 6.0E-29 T 13-10-2018 IPR002938 FAD-binding domain GO:0071949 Astex_2313 d6cfe665f388904d44d999e0d9c61e98 415 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 6 400 4.2E-125 T 13-10-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 Astex_2313 d6cfe665f388904d44d999e0d9c61e98 415 Gene3D G3DSA:3.50.50.60 6 349 2.0E-93 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_2313 d6cfe665f388904d44d999e0d9c61e98 415 SUPERFAMILY SSF51905 5 396 1.3E-59 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_2313 d6cfe665f388904d44d999e0d9c61e98 415 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 291 306 5.2E-19 T 13-10-2018 Astex_2313 d6cfe665f388904d44d999e0d9c61e98 415 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 306 322 5.2E-19 T 13-10-2018 Astex_2313 d6cfe665f388904d44d999e0d9c61e98 415 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 167 182 5.2E-19 T 13-10-2018 Astex_2313 d6cfe665f388904d44d999e0d9c61e98 415 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 5.2E-19 T 13-10-2018 Astex_0184 8865e5cca2d41b91c40758c5b46a59ac 156 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 24 122 4.0E-32 T 13-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 Astex_0184 8865e5cca2d41b91c40758c5b46a59ac 156 Gene3D G3DSA:3.30.300.20 16 130 4.3E-24 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta Astex_0184 8865e5cca2d41b91c40758c5b46a59ac 156 Pfam PF02033 Ribosome-binding factor A 21 135 2.1E-28 T 13-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 Astex_0184 8865e5cca2d41b91c40758c5b46a59ac 156 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 21 135 1.7E-15 T 13-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 Astex_0184 8865e5cca2d41b91c40758c5b46a59ac 156 SUPERFAMILY SSF89919 17 135 2.35E-28 T 13-10-2018 IPR023799 Ribosome-binding factor A domain superfamily Astex_0184 8865e5cca2d41b91c40758c5b46a59ac 156 ProSitePatterns PS01319 Ribosome-binding factor A signature. 101 122 - T 13-10-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 Astex_0184 8865e5cca2d41b91c40758c5b46a59ac 156 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 20 135 23.684 T 13-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 Astex_1723 f0b489cbef007fdbddb81bc0fcf9af4e 138 SUPERFAMILY SSF51182 1 136 5.0E-53 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily Astex_1723 f0b489cbef007fdbddb81bc0fcf9af4e 138 Gene3D G3DSA:2.60.120.10 1 138 3.7E-56 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Astex_1723 f0b489cbef007fdbddb81bc0fcf9af4e 138 Pfam PF06172 Cupin superfamily (DUF985) 5 130 9.5E-48 T 13-10-2018 IPR009327 Cupin domain of unknown function DUF985 Astex_3323 b978c39f35e4a9c60c648109e523b6d6 382 SUPERFAMILY SSF47384 145 225 3.73E-16 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Astex_3323 b978c39f35e4a9c60c648109e523b6d6 382 SMART SM00448 19 133 1.3E-27 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_3323 b978c39f35e4a9c60c648109e523b6d6 382 SUPERFAMILY SSF52172 18 161 7.12E-37 T 13-10-2018 IPR011006 CheY-like superfamily Astex_3323 b978c39f35e4a9c60c648109e523b6d6 382 Pfam PF00072 Response regulator receiver domain 21 133 7.4E-25 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_3323 b978c39f35e4a9c60c648109e523b6d6 382 Gene3D G3DSA:1.10.287.130 148 229 9.6E-14 T 13-10-2018 Astex_3323 b978c39f35e4a9c60c648109e523b6d6 382 Gene3D G3DSA:3.40.50.2300 15 147 2.0E-33 T 13-10-2018 Astex_3323 b978c39f35e4a9c60c648109e523b6d6 382 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 273 378 1.1E-23 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_3323 b978c39f35e4a9c60c648109e523b6d6 382 PRINTS PR00344 Bacterial sensor protein C-terminal signature 364 377 3.6E-14 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_3323 b978c39f35e4a9c60c648109e523b6d6 382 PRINTS PR00344 Bacterial sensor protein C-terminal signature 340 358 3.6E-14 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_3323 b978c39f35e4a9c60c648109e523b6d6 382 PRINTS PR00344 Bacterial sensor protein C-terminal signature 307 321 3.6E-14 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_3323 b978c39f35e4a9c60c648109e523b6d6 382 Gene3D G3DSA:3.30.565.10 230 381 7.2E-36 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_3323 b978c39f35e4a9c60c648109e523b6d6 382 Pfam PF00512 His Kinase A (phospho-acceptor) domain 160 225 8.8E-9 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_3323 b978c39f35e4a9c60c648109e523b6d6 382 SUPERFAMILY SSF55874 217 378 3.27E-38 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_3323 b978c39f35e4a9c60c648109e523b6d6 382 SMART SM00388 159 227 1.6E-8 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_3323 b978c39f35e4a9c60c648109e523b6d6 382 SMART SM00387 268 380 2.4E-27 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_2865 5dd99632564cd9eb1c1a4b8072b3bcdb 197 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 7.9E-13 T 13-10-2018 Astex_2865 5dd99632564cd9eb1c1a4b8072b3bcdb 197 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 7.9E-13 T 13-10-2018 Astex_2865 5dd99632564cd9eb1c1a4b8072b3bcdb 197 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 7.9E-13 T 13-10-2018 Astex_2865 5dd99632564cd9eb1c1a4b8072b3bcdb 197 SUPERFAMILY SSF52317 1 187 5.35E-58 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Astex_2865 5dd99632564cd9eb1c1a4b8072b3bcdb 197 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 186 4.3E-73 T 13-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 Astex_2865 5dd99632564cd9eb1c1a4b8072b3bcdb 197 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 2.4E-6 T 13-10-2018 Astex_2865 5dd99632564cd9eb1c1a4b8072b3bcdb 197 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 2.4E-6 T 13-10-2018 Astex_2865 5dd99632564cd9eb1c1a4b8072b3bcdb 197 Gene3D G3DSA:3.40.50.880 1 190 1.1E-65 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Astex_2865 5dd99632564cd9eb1c1a4b8072b3bcdb 197 PRINTS PR00097 Anthranilate synthase component II signature 119 131 8.9E-36 T 13-10-2018 Astex_2865 5dd99632564cd9eb1c1a4b8072b3bcdb 197 PRINTS PR00097 Anthranilate synthase component II signature 164 177 8.9E-36 T 13-10-2018 Astex_2865 5dd99632564cd9eb1c1a4b8072b3bcdb 197 PRINTS PR00097 Anthranilate synthase component II signature 99 107 8.9E-36 T 13-10-2018 Astex_2865 5dd99632564cd9eb1c1a4b8072b3bcdb 197 PRINTS PR00097 Anthranilate synthase component II signature 2 16 8.9E-36 T 13-10-2018 Astex_2865 5dd99632564cd9eb1c1a4b8072b3bcdb 197 PRINTS PR00097 Anthranilate synthase component II signature 47 56 8.9E-36 T 13-10-2018 Astex_2865 5dd99632564cd9eb1c1a4b8072b3bcdb 197 PRINTS PR00097 Anthranilate synthase component II signature 74 85 8.9E-36 T 13-10-2018 Astex_2865 5dd99632564cd9eb1c1a4b8072b3bcdb 197 Pfam PF00117 Glutamine amidotransferase class-I 3 185 1.6E-56 T 13-10-2018 IPR017926 Glutamine amidotransferase Astex_1278 abff53d4130dee07610752227cbb33e3 400 Gene3D G3DSA:1.10.287.470 112 185 2.9E-93 T 13-10-2018 Astex_1278 abff53d4130dee07610752227cbb33e3 400 Gene3D G3DSA:2.40.420.20 313 381 2.9E-93 T 13-10-2018 Astex_1278 abff53d4130dee07610752227cbb33e3 400 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 53 383 6.2E-84 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 Astex_1278 abff53d4130dee07610752227cbb33e3 400 Gene3D G3DSA:2.40.30.170 67 312 2.9E-93 T 13-10-2018 Astex_1278 abff53d4130dee07610752227cbb33e3 400 Gene3D G3DSA:2.40.50.100 77 222 2.9E-93 T 13-10-2018 Astex_1278 abff53d4130dee07610752227cbb33e3 400 SUPERFAMILY SSF111369 68 307 1.57E-59 T 13-10-2018 Astex_1278 abff53d4130dee07610752227cbb33e3 400 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 79 302 5.3E-15 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain Astex_0851 bccbbdbaac55d41af67db16417534d1b 262 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 145 243 8.2E-29 T 13-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G Astex_0851 bccbbdbaac55d41af67db16417534d1b 262 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 2 136 4.9E-47 T 13-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G Astex_0851 bccbbdbaac55d41af67db16417534d1b 262 Pfam PF00460 Flagella basal body rod protein 4 34 1.8E-12 T 13-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 Astex_0851 bccbbdbaac55d41af67db16417534d1b 262 SUPERFAMILY SSF117143 92 222 3.27E-33 T 13-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like Astex_0851 bccbbdbaac55d41af67db16417534d1b 262 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 182 259 4.1E-25 T 13-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain Astex_0851 bccbbdbaac55d41af67db16417534d1b 262 TIGRFAM TIGR02488 flgG_G_neg: flagellar basal-body rod protein FlgG 3 259 4.0E-108 T 13-10-2018 IPR012834 Flagellar basal-body rod FlgG GO:0009426|GO:0071973 Astex_0384 3e1fe6dfca41437308ca6ac4ba072ce2 724 SUPERFAMILY SSF50692 611 723 1.12E-21 T 13-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily Astex_0384 3e1fe6dfca41437308ca6ac4ba072ce2 724 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 27 721 3.4E-204 T 13-10-2018 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 Astex_0384 3e1fe6dfca41437308ca6ac4ba072ce2 724 PIRSF PIRSF000144 3 724 1.1E-172 T 13-10-2018 Astex_0384 3e1fe6dfca41437308ca6ac4ba072ce2 724 Pfam PF01568 Molydopterin dinucleotide binding domain 617 717 3.2E-19 T 13-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 Astex_0384 3e1fe6dfca41437308ca6ac4ba072ce2 724 Gene3D G3DSA:3.40.228.10 181 396 1.5E-83 T 13-10-2018 Astex_0384 3e1fe6dfca41437308ca6ac4ba072ce2 724 Gene3D G3DSA:3.40.50.740 118 570 1.5E-83 T 13-10-2018 Astex_0384 3e1fe6dfca41437308ca6ac4ba072ce2 724 Pfam PF00384 Molybdopterin oxidoreductase 106 398 3.1E-30 T 13-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_0384 3e1fe6dfca41437308ca6ac4ba072ce2 724 Gene3D G3DSA:2.40.40.20 608 722 6.6E-14 T 13-10-2018 Astex_0384 3e1fe6dfca41437308ca6ac4ba072ce2 724 SUPERFAMILY SSF53706 34 610 1.96E-118 T 13-10-2018 Astex_2010 6ddfab13cff343fdf6f982c8eef789dd 809 Gene3D G3DSA:2.70.98.10 43 332 1.1E-63 T 13-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 Astex_2010 6ddfab13cff343fdf6f982c8eef789dd 809 TIGRFAM TIGR01535 glucan_glucosid: glucan 1,4-alpha-glucosidase 86 802 3.5E-232 T 13-10-2018 IPR006425 Glucoamylase, bacterial KEGG: 00500+3.2.1.3|MetaCyc: PWY-5941 Astex_2010 6ddfab13cff343fdf6f982c8eef789dd 809 Pfam PF00723 Glycosyl hydrolases family 15 344 787 4.0E-43 T 13-10-2018 IPR011613 GH15-like domain Reactome: R-HSA-70221 Astex_2010 6ddfab13cff343fdf6f982c8eef789dd 809 SUPERFAMILY SSF48208 339 801 8.51E-71 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 Astex_2010 6ddfab13cff343fdf6f982c8eef789dd 809 Gene3D G3DSA:1.50.10.10 336 809 1.7E-141 T 13-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 Astex_2010 6ddfab13cff343fdf6f982c8eef789dd 809 Pfam PF09137 Glucodextranase, domain N 46 328 2.2E-72 T 13-10-2018 IPR015220 Glucodextranase, N-terminal KEGG: 00500+3.2.1.3|MetaCyc: PWY-5941 Astex_2010 6ddfab13cff343fdf6f982c8eef789dd 809 SUPERFAMILY SSF74650 46 331 1.54E-69 T 13-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 Astex_0436 d1a8f6088d40c7a44d4e5338e5725f42 470 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 319 326 - T 13-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 Astex_0436 d1a8f6088d40c7a44d4e5338e5725f42 470 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 151 443 2.7E-97 T 13-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 Astex_0436 d1a8f6088d40c7a44d4e5338e5725f42 470 SUPERFAMILY SSF53187 147 468 1.57E-96 T 13-10-2018 Astex_0436 d1a8f6088d40c7a44d4e5338e5725f42 470 Gene3D G3DSA:3.40.220.10 11 127 1.9E-12 T 13-10-2018 Astex_0436 d1a8f6088d40c7a44d4e5338e5725f42 470 SUPERFAMILY SSF52949 16 121 4.06E-5 T 13-10-2018 Astex_0436 d1a8f6088d40c7a44d4e5338e5725f42 470 Gene3D G3DSA:3.40.630.10 137 469 9.5E-111 T 13-10-2018 Astex_0436 d1a8f6088d40c7a44d4e5338e5725f42 470 PRINTS PR00481 Cytosol aminopeptidase signature 293 314 1.1E-45 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 Astex_0436 d1a8f6088d40c7a44d4e5338e5725f42 470 PRINTS PR00481 Cytosol aminopeptidase signature 315 335 1.1E-45 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 Astex_0436 d1a8f6088d40c7a44d4e5338e5725f42 470 PRINTS PR00481 Cytosol aminopeptidase signature 343 358 1.1E-45 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 Astex_0436 d1a8f6088d40c7a44d4e5338e5725f42 470 PRINTS PR00481 Cytosol aminopeptidase signature 256 277 1.1E-45 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 Astex_0436 d1a8f6088d40c7a44d4e5338e5725f42 470 PRINTS PR00481 Cytosol aminopeptidase signature 234 251 1.1E-45 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 Astex_1390 05ad5822e2d95161e45a958e27630e30 82 Gene3D G3DSA:3.30.50.10 1 66 3.4E-13 T 13-10-2018 IPR013088 Zinc finger, NHR/GATA-type GO:0006355|GO:0008270 Reactome: R-HSA-383280 Astex_1390 05ad5822e2d95161e45a958e27630e30 82 SUPERFAMILY SSF57716 3 61 4.56E-10 T 13-10-2018 Astex_1390 05ad5822e2d95161e45a958e27630e30 82 Pfam PF03884 DNA gyrase inhibitor YacG 6 54 1.8E-10 T 13-10-2018 IPR005584 DNA gyrase inhibitor YacG GO:0008270 Astex_0412 71828e9a49ea17a3a47427aa08fa2f0d 222 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 162 179 3.5E-9 T 13-10-2018 Astex_0412 71828e9a49ea17a3a47427aa08fa2f0d 222 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 180 199 3.5E-9 T 13-10-2018 Astex_0412 71828e9a49ea17a3a47427aa08fa2f0d 222 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 200 220 3.5E-9 T 13-10-2018 Astex_0412 71828e9a49ea17a3a47427aa08fa2f0d 222 Pfam PF13488 Glycine zipper 38 86 6.8E-12 T 13-10-2018 IPR039567 Glycine zipper domain Astex_0412 71828e9a49ea17a3a47427aa08fa2f0d 222 ProSitePatterns PS01068 OmpA-like domain. 149 193 - T 13-10-2018 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 Astex_0412 71828e9a49ea17a3a47427aa08fa2f0d 222 SUPERFAMILY SSF103088 104 219 7.32E-38 T 13-10-2018 IPR036737 OmpA-like domain superfamily Astex_0412 71828e9a49ea17a3a47427aa08fa2f0d 222 PRINTS PR01021 OMPA domain signature 117 139 8.7E-9 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 Astex_0412 71828e9a49ea17a3a47427aa08fa2f0d 222 PRINTS PR01021 OMPA domain signature 162 178 8.7E-9 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 Astex_0412 71828e9a49ea17a3a47427aa08fa2f0d 222 PRINTS PR01021 OMPA domain signature 147 162 8.7E-9 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 Astex_0412 71828e9a49ea17a3a47427aa08fa2f0d 222 Gene3D G3DSA:3.30.1330.60 80 222 8.4E-49 T 13-10-2018 IPR036737 OmpA-like domain superfamily Astex_0412 71828e9a49ea17a3a47427aa08fa2f0d 222 Pfam PF00691 OmpA family 116 211 1.8E-21 T 13-10-2018 IPR006665 OmpA-like domain Astex_1985 4e919f172cf2f0ed1667b6c794a8b3f3 695 SUPERFAMILY SSF51445 309 609 5.2E-68 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_1985 4e919f172cf2f0ed1667b6c794a8b3f3 695 SUPERFAMILY SSF49303 198 303 6.62E-14 T 13-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily Astex_1985 4e919f172cf2f0ed1667b6c794a8b3f3 695 PRINTS PR00132 Glycosyl hydrolase family 2 signature 315 329 2.1E-11 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_1985 4e919f172cf2f0ed1667b6c794a8b3f3 695 PRINTS PR00132 Glycosyl hydrolase family 2 signature 111 126 2.1E-11 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_1985 4e919f172cf2f0ed1667b6c794a8b3f3 695 PRINTS PR00132 Glycosyl hydrolase family 2 signature 412 427 2.1E-11 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_1985 4e919f172cf2f0ed1667b6c794a8b3f3 695 PRINTS PR00132 Glycosyl hydrolase family 2 signature 346 364 2.1E-11 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_1985 4e919f172cf2f0ed1667b6c794a8b3f3 695 Gene3D G3DSA:2.60.40.10 609 691 3.4E-20 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_1985 4e919f172cf2f0ed1667b6c794a8b3f3 695 SUPERFAMILY SSF49785 15 181 1.58E-41 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_1985 4e919f172cf2f0ed1667b6c794a8b3f3 695 Gene3D G3DSA:3.20.20.80 305 608 1.2E-82 T 13-10-2018 Astex_1985 4e919f172cf2f0ed1667b6c794a8b3f3 695 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 82 182 1.3E-18 T 13-10-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_1985 4e919f172cf2f0ed1667b6c794a8b3f3 695 Gene3D G3DSA:2.60.120.260 26 183 1.0E-40 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_1985 4e919f172cf2f0ed1667b6c794a8b3f3 695 Gene3D G3DSA:2.60.40.10 186 303 8.6E-24 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_1985 4e919f172cf2f0ed1667b6c794a8b3f3 695 Pfam PF00703 Glycosyl hydrolases family 2 201 303 1.6E-13 T 13-10-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_1985 4e919f172cf2f0ed1667b6c794a8b3f3 695 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 311 514 5.8E-31 T 13-10-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 Astex_0633 bdad91a0eafcb8b646468adbc5691952 301 SMART SM00448 16 137 1.5E-30 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_0633 bdad91a0eafcb8b646468adbc5691952 301 Pfam PF00072 Response regulator receiver domain 18 135 8.4E-23 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_0633 bdad91a0eafcb8b646468adbc5691952 301 Gene3D G3DSA:3.40.50.2300 14 151 1.4E-30 T 13-10-2018 Astex_0633 bdad91a0eafcb8b646468adbc5691952 301 SUPERFAMILY SSF52172 16 147 6.83E-32 T 13-10-2018 IPR011006 CheY-like superfamily Astex_1825 6c4c7184be56dd75885785bdba6eb57a 547 SMART SM00388 324 388 9.7E-5 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_1825 6c4c7184be56dd75885785bdba6eb57a 547 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 435 545 3.1E-17 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_1825 6c4c7184be56dd75885785bdba6eb57a 547 Gene3D G3DSA:1.10.287.130 263 383 5.5E-12 T 13-10-2018 Astex_1825 6c4c7184be56dd75885785bdba6eb57a 547 Gene3D G3DSA:3.30.565.10 393 547 6.3E-29 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_1825 6c4c7184be56dd75885785bdba6eb57a 547 SUPERFAMILY SSF55874 389 544 7.73E-30 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_1825 6c4c7184be56dd75885785bdba6eb57a 547 PRINTS PR00344 Bacterial sensor protein C-terminal signature 531 544 1.2E-14 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1825 6c4c7184be56dd75885785bdba6eb57a 547 PRINTS PR00344 Bacterial sensor protein C-terminal signature 495 505 1.2E-14 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1825 6c4c7184be56dd75885785bdba6eb57a 547 PRINTS PR00344 Bacterial sensor protein C-terminal signature 477 491 1.2E-14 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1825 6c4c7184be56dd75885785bdba6eb57a 547 PRINTS PR00344 Bacterial sensor protein C-terminal signature 507 525 1.2E-14 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1825 6c4c7184be56dd75885785bdba6eb57a 547 SMART SM00387 434 547 4.3E-25 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_1825 6c4c7184be56dd75885785bdba6eb57a 547 SUPERFAMILY SSF47384 317 386 5.69E-8 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Astex_0219 9a67a3835c2e907d786baad7cad965a5 189 SUPERFAMILY SSF52172 17 175 1.99E-33 T 13-10-2018 IPR011006 CheY-like superfamily Astex_0219 9a67a3835c2e907d786baad7cad965a5 189 Pfam PF02954 Bacterial regulatory protein, Fis family 153 181 3.8E-5 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 Astex_0219 9a67a3835c2e907d786baad7cad965a5 189 Gene3D G3DSA:3.40.50.2300 18 132 7.7E-29 T 13-10-2018 Astex_0219 9a67a3835c2e907d786baad7cad965a5 189 SMART SM00448 18 129 5.2E-24 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_0219 9a67a3835c2e907d786baad7cad965a5 189 Gene3D G3DSA:1.10.10.60 133 189 1.1E-23 T 13-10-2018 Astex_0219 9a67a3835c2e907d786baad7cad965a5 189 Pfam PF00072 Response regulator receiver domain 21 129 6.1E-22 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1906 935a5b25ebeb9bc7c546bd7c9e5f4adf 137 Pfam PF07883 Cupin domain 67 128 3.2E-7 T 13-10-2018 IPR013096 Cupin 2, conserved barrel Astex_1906 935a5b25ebeb9bc7c546bd7c9e5f4adf 137 Gene3D G3DSA:2.60.120.10 18 133 4.5E-14 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Astex_1906 935a5b25ebeb9bc7c546bd7c9e5f4adf 137 SUPERFAMILY SSF51182 26 129 1.69E-16 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily Astex_3427 76d9f080ec89ae95e6d082ac7c871ebd 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 4.4E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_3427 76d9f080ec89ae95e6d082ac7c871ebd 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 4.4E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_3427 76d9f080ec89ae95e6d082ac7c871ebd 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 4.4E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_3427 76d9f080ec89ae95e6d082ac7c871ebd 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 261 3.1E-52 T 13-10-2018 Astex_3427 76d9f080ec89ae95e6d082ac7c871ebd 263 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Astex_3427 76d9f080ec89ae95e6d082ac7c871ebd 263 SUPERFAMILY SSF51735 7 262 8.06E-70 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_3427 76d9f080ec89ae95e6d082ac7c871ebd 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 244 9.4E-39 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_3427 76d9f080ec89ae95e6d082ac7c871ebd 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 9.4E-39 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_3427 76d9f080ec89ae95e6d082ac7c871ebd 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 9.4E-39 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_3427 76d9f080ec89ae95e6d082ac7c871ebd 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 9.4E-39 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_3427 76d9f080ec89ae95e6d082ac7c871ebd 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 9.4E-39 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_3427 76d9f080ec89ae95e6d082ac7c871ebd 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 9.4E-39 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_3427 76d9f080ec89ae95e6d082ac7c871ebd 263 Gene3D G3DSA:3.40.50.720 1 263 2.1E-73 T 13-10-2018 Astex_3427 76d9f080ec89ae95e6d082ac7c871ebd 263 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 193 0.0041 T 13-10-2018 Astex_1873 c0cc3d625aa9cf7f5b08cb97834e49b7 118 Pfam PF00072 Response regulator receiver domain 4 112 2.1E-20 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1873 c0cc3d625aa9cf7f5b08cb97834e49b7 118 SUPERFAMILY SSF52172 1 117 2.13E-28 T 13-10-2018 IPR011006 CheY-like superfamily Astex_1873 c0cc3d625aa9cf7f5b08cb97834e49b7 118 Gene3D G3DSA:3.40.50.2300 1 118 2.3E-28 T 13-10-2018 Astex_1873 c0cc3d625aa9cf7f5b08cb97834e49b7 118 SMART SM00448 2 112 4.4E-21 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_0669 b19effe8c455a2de05c5f17ddb11e5eb 572 SMART SM00304 223 276 5.3E-5 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Astex_0669 b19effe8c455a2de05c5f17ddb11e5eb 572 Gene3D G3DSA:1.10.287.950 278 567 2.3E-52 T 13-10-2018 Astex_0669 b19effe8c455a2de05c5f17ddb11e5eb 572 SUPERFAMILY SSF58104 252 565 7.85E-52 T 13-10-2018 Astex_0669 b19effe8c455a2de05c5f17ddb11e5eb 572 SMART SM00283 312 566 6.1E-39 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_0669 b19effe8c455a2de05c5f17ddb11e5eb 572 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 263 568 2.0E-4 T 13-10-2018 Astex_0669 b19effe8c455a2de05c5f17ddb11e5eb 572 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 371 538 4.5E-32 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_0669 b19effe8c455a2de05c5f17ddb11e5eb 572 Gene3D G3DSA:1.20.1480.50 169 277 6.0E-9 T 13-10-2018 Astex_0669 b19effe8c455a2de05c5f17ddb11e5eb 572 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 26 51 2.5E-21 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_0669 b19effe8c455a2de05c5f17ddb11e5eb 572 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 487 516 2.5E-21 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_0669 b19effe8c455a2de05c5f17ddb11e5eb 572 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 410 437 2.5E-21 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_0669 b19effe8c455a2de05c5f17ddb11e5eb 572 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 439 468 2.5E-21 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_0434 e92bd309f8274f704a9318d9c1fac9ea 350 Gene3D G3DSA:1.10.620.20 15 317 2.2E-88 T 13-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 Astex_0434 e92bd309f8274f704a9318d9c1fac9ea 350 SUPERFAMILY SSF47240 17 324 8.11E-86 T 13-10-2018 IPR009078 Ferritin-like superfamily Astex_0434 e92bd309f8274f704a9318d9c1fac9ea 350 PIRSF PIRSF000355 11 326 3.1E-106 T 13-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Astex_0434 e92bd309f8274f704a9318d9c1fac9ea 350 Pfam PF00268 Ribonucleotide reductase, small chain 20 291 3.7E-74 T 13-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Astex_0161 7e123e0a5f94e8b0391ad9233b14376e 188 Pfam PF08712 Scaffold protein Nfu/NifU N terminal 3 91 1.5E-28 T 13-10-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal Astex_0161 7e123e0a5f94e8b0391ad9233b14376e 188 SMART SM00932 3 91 1.0E-41 T 13-10-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal Astex_0161 7e123e0a5f94e8b0391ad9233b14376e 188 Gene3D G3DSA:3.30.300.130 112 187 1.5E-26 T 13-10-2018 IPR034904 Fe-S cluster assembly domain superfamily Astex_0161 7e123e0a5f94e8b0391ad9233b14376e 188 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 121 186 3.0E-24 T 13-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 Astex_0161 7e123e0a5f94e8b0391ad9233b14376e 188 Pfam PF01106 NifU-like domain 117 185 3.8E-26 T 13-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 Astex_0161 7e123e0a5f94e8b0391ad9233b14376e 188 PIRSF PIRSF036773 1 188 4.9E-71 T 13-10-2018 IPR035433 NFU1-like Astex_0161 7e123e0a5f94e8b0391ad9233b14376e 188 SUPERFAMILY SSF117916 107 187 1.09E-23 T 13-10-2018 IPR034904 Fe-S cluster assembly domain superfamily Astex_0161 7e123e0a5f94e8b0391ad9233b14376e 188 SUPERFAMILY SSF110836 1 91 1.83E-26 T 13-10-2018 IPR036498 Scaffold protein Nfu/NifU, N-terminal domain superfamily Astex_0161 7e123e0a5f94e8b0391ad9233b14376e 188 Gene3D G3DSA:3.30.1370.70 1 98 9.0E-34 T 13-10-2018 IPR036498 Scaffold protein Nfu/NifU, N-terminal domain superfamily Astex_1396 0f5d7d30e242ec2810e85db05e9ccb41 67 SMART SM00357 3 67 4.7E-23 T 13-10-2018 IPR011129 Cold shock domain GO:0003676 Astex_1396 0f5d7d30e242ec2810e85db05e9ccb41 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 13-10-2018 IPR019844 Cold-shock conserved site Astex_1396 0f5d7d30e242ec2810e85db05e9ccb41 67 Gene3D G3DSA:2.40.50.140 1 66 5.4E-24 T 13-10-2018 Astex_1396 0f5d7d30e242ec2810e85db05e9ccb41 67 PRINTS PR00050 Cold shock protein signature 40 58 1.2E-10 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Astex_1396 0f5d7d30e242ec2810e85db05e9ccb41 67 PRINTS PR00050 Cold shock protein signature 4 19 1.2E-10 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Astex_1396 0f5d7d30e242ec2810e85db05e9ccb41 67 PRINTS PR00050 Cold shock protein signature 25 34 1.2E-10 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Astex_1396 0f5d7d30e242ec2810e85db05e9ccb41 67 PIRSF PIRSF002599 1 67 2.7E-20 T 13-10-2018 IPR012156 Cold shock, CspA GO:0003676 Astex_1396 0f5d7d30e242ec2810e85db05e9ccb41 67 SUPERFAMILY SSF50249 1 66 1.97E-20 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Astex_1396 0f5d7d30e242ec2810e85db05e9ccb41 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 9.7E-23 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Astex_3014 6b1b80f580f69d8dd2422c9804f899a1 161 Pfam PF00805 Pentapeptide repeats (8 copies) 33 72 1.0E-7 T 13-10-2018 IPR001646 Pentapeptide repeat Astex_3014 6b1b80f580f69d8dd2422c9804f899a1 161 Pfam PF00805 Pentapeptide repeats (8 copies) 93 128 1.2E-11 T 13-10-2018 IPR001646 Pentapeptide repeat Astex_3014 6b1b80f580f69d8dd2422c9804f899a1 161 SUPERFAMILY SSF141571 31 134 1.57E-25 T 13-10-2018 Astex_3014 6b1b80f580f69d8dd2422c9804f899a1 161 Gene3D G3DSA:2.160.20.100 24 148 2.7E-24 T 13-10-2018 Astex_1691 7d917cabd47a086b5d4a43ca5cdcb3d2 1419 Pfam PF04357 TamB, inner membrane protein subunit of TAM complex 1075 1419 2.0E-58 T 13-10-2018 IPR007452 Translocation and assembly module TamB Astex_3678 74cc463d085bc96cd3a47c170a034fe3 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 56 72 7.4E-6 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Astex_3678 74cc463d085bc96cd3a47c170a034fe3 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 56 7.4E-6 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Astex_3678 74cc463d085bc96cd3a47c170a034fe3 249 SMART SM00345 24 82 1.6E-7 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Astex_3678 74cc463d085bc96cd3a47c170a034fe3 249 SMART SM00895 111 232 1.0E-18 T 13-10-2018 IPR011711 GntR, C-terminal Astex_3678 74cc463d085bc96cd3a47c170a034fe3 249 Gene3D G3DSA:1.10.10.10 16 83 6.3E-14 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_3678 74cc463d085bc96cd3a47c170a034fe3 249 Gene3D G3DSA:1.20.120.530 105 240 2.5E-24 T 13-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal Astex_3678 74cc463d085bc96cd3a47c170a034fe3 249 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 82 2.5E-11 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Astex_3678 74cc463d085bc96cd3a47c170a034fe3 249 SUPERFAMILY SSF48008 109 238 4.71E-25 T 13-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal Astex_3678 74cc463d085bc96cd3a47c170a034fe3 249 Pfam PF07729 FCD domain 111 228 1.0E-20 T 13-10-2018 IPR011711 GntR, C-terminal Astex_3678 74cc463d085bc96cd3a47c170a034fe3 249 SUPERFAMILY SSF46785 17 86 2.21E-12 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_3007 c7992a31d7852ea7404f25e577162fe3 459 Pfam PF02785 Biotin carboxylase C-terminal domain 341 446 2.5E-37 T 13-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Astex_3007 c7992a31d7852ea7404f25e577162fe3 459 Pfam PF00289 Biotin carboxylase, N-terminal domain 8 116 2.4E-45 T 13-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Astex_3007 c7992a31d7852ea7404f25e577162fe3 459 SUPERFAMILY SSF51246 336 449 9.42E-42 T 13-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 Astex_3007 c7992a31d7852ea7404f25e577162fe3 459 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 121 327 4.4E-79 T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Astex_3007 c7992a31d7852ea7404f25e577162fe3 459 Gene3D G3DSA:3.30.470.130 2 452 4.4E-187 T 13-10-2018 Astex_3007 c7992a31d7852ea7404f25e577162fe3 459 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 159 173 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Astex_3007 c7992a31d7852ea7404f25e577162fe3 459 SMART SM00878 341 446 4.1E-61 T 13-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Astex_3007 c7992a31d7852ea7404f25e577162fe3 459 SUPERFAMILY SSF52440 5 119 6.83E-50 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily Astex_3007 c7992a31d7852ea7404f25e577162fe3 459 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 8 450 2.0E-216 T 13-10-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 Astex_3007 c7992a31d7852ea7404f25e577162fe3 459 SUPERFAMILY SSF56059 89 351 3.89E-67 T 13-10-2018 Astex_3007 c7992a31d7852ea7404f25e577162fe3 459 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 291 298 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Astex_1287 fc81de6fa1cafea6360fb85b3814dcb7 846 SUPERFAMILY SSF82171 129 558 1.7E-22 T 13-10-2018 Astex_1287 fc81de6fa1cafea6360fb85b3814dcb7 846 Gene3D G3DSA:3.40.50.1820 571 841 1.8E-51 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1287 fc81de6fa1cafea6360fb85b3814dcb7 846 Gene3D G3DSA:2.120.10.30 119 225 3.1E-12 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like Astex_1287 fc81de6fa1cafea6360fb85b3814dcb7 846 Pfam PF00326 Prolyl oligopeptidase family 681 834 5.4E-27 T 13-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 Astex_1287 fc81de6fa1cafea6360fb85b3814dcb7 846 SUPERFAMILY SSF53474 576 834 1.52E-47 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1287 fc81de6fa1cafea6360fb85b3814dcb7 846 Pfam PF07676 WD40-like Beta Propeller Repeat 151 175 0.0094 T 13-10-2018 IPR011659 WD40-like Beta Propeller Astex_2761 c3dee2006068174a4d994837db4723ac 488 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 17 479 5.8E-190 T 13-10-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 Astex_2761 c3dee2006068174a4d994837db4723ac 488 SUPERFAMILY SSF101960 37 485 7.98E-137 T 13-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily Astex_2761 c3dee2006068174a4d994837db4723ac 488 Pfam PF01458 Uncharacterized protein family (UPF0051) 226 459 3.5E-66 T 13-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 Astex_1411 8af70bf12447713a0d07182318376ffc 957 SUPERFAMILY SSF74650 18 199 5.65E-21 T 13-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 Astex_1411 8af70bf12447713a0d07182318376ffc 957 Gene3D G3DSA:3.20.20.80 394 762 1.1E-122 T 13-10-2018 Astex_1411 8af70bf12447713a0d07182318376ffc 957 Pfam PF17137 Domain of unknown function (DUF5110) 863 929 1.5E-19 T 13-10-2018 IPR033403 Domain of unknown function DUF5110 Astex_1411 8af70bf12447713a0d07182318376ffc 957 Pfam PF16338 Domain of unknown function (DUF4968) 37 119 4.9E-8 T 13-10-2018 IPR032513 Alpha-glucosidase, domain of unknown function DUF4968 Astex_1411 8af70bf12447713a0d07182318376ffc 957 Pfam PF01055 Glycosyl hydrolases family 31 374 846 1.3E-125 T 13-10-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 Astex_1411 8af70bf12447713a0d07182318376ffc 957 Gene3D G3DSA:2.60.120.380 205 352 1.9E-115 T 13-10-2018 Astex_1411 8af70bf12447713a0d07182318376ffc 957 SUPERFAMILY SSF51011 761 841 1.8E-20 T 13-10-2018 Astex_1411 8af70bf12447713a0d07182318376ffc 957 Gene3D G3DSA:2.60.40.1760 28 393 1.9E-115 T 13-10-2018 Astex_1411 8af70bf12447713a0d07182318376ffc 957 SUPERFAMILY SSF56988 220 357 1.12E-5 T 13-10-2018 Astex_1411 8af70bf12447713a0d07182318376ffc 957 Gene3D G3DSA:2.60.40.1180 843 957 1.6E-32 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta Astex_1411 8af70bf12447713a0d07182318376ffc 957 SUPERFAMILY SSF51445 384 758 2.24E-59 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_1411 8af70bf12447713a0d07182318376ffc 957 Gene3D G3DSA:2.60.40.1180 766 842 2.8E-26 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta Astex_1411 8af70bf12447713a0d07182318376ffc 957 SMART SM00758 219 362 0.0064 T 13-10-2018 IPR011658 PA14 domain Astex_2309 7b164f396b557c8ec90783314850e5a0 326 Gene3D G3DSA:3.90.25.10 174 307 6.6E-113 T 13-10-2018 Astex_2309 7b164f396b557c8ec90783314850e5a0 326 Gene3D G3DSA:3.40.50.720 5 253 6.6E-113 T 13-10-2018 Astex_2309 7b164f396b557c8ec90783314850e5a0 326 SUPERFAMILY SSF51735 1 323 1.04E-80 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_2309 7b164f396b557c8ec90783314850e5a0 326 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 4 324 1.2E-120 T 13-10-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 Astex_2309 7b164f396b557c8ec90783314850e5a0 326 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 253 3.2E-47 T 13-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 Astex_3796 b37c65401799c04630ca727186d4f2e4 607 Pfam PF06986 Type-1V conjugative transfer system mating pair stabilisation 312 555 1.2E-65 T 13-10-2018 IPR014121 Type-F conjugative transfer system mating-pair stabilisation protein TraN Astex_2624 1072e8f3284947ac4446ec42f883da66 388 SUPERFAMILY SSF51695 44 379 1.57E-79 T 13-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 Astex_2624 1072e8f3284947ac4446ec42f883da66 388 Gene3D G3DSA:3.20.20.190 43 379 2.0E-110 T 13-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 Astex_2624 1072e8f3284947ac4446ec42f883da66 388 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 50 374 1.1E-56 T 13-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 Astex_0014 46393f67505b0f8ec0e70f2a326a2511 79 Pfam PF07896 Protein of unknown function (DUF1674) 37 79 1.3E-15 T 13-10-2018 IPR012875 Protein of unknown function DUF1674 Astex_0945 d26bc10b57bf661614ee421840059870 243 SUPERFAMILY SSF50447 1 218 1.5E-81 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily Astex_0945 d26bc10b57bf661614ee421840059870 243 Gene3D G3DSA:2.40.30.10 122 211 8.8E-17 T 13-10-2018 Astex_0945 d26bc10b57bf661614ee421840059870 243 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 4 205 7.1E-85 T 13-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0945 d26bc10b57bf661614ee421840059870 243 Pfam PF00297 Ribosomal protein L3 68 183 7.0E-15 T 13-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_0945 d26bc10b57bf661614ee421840059870 243 ProSitePatterns PS00474 Ribosomal protein L3 signature. 102 125 - T 13-10-2018 IPR019926 Ribosomal protein L3, conserved site Astex_0945 d26bc10b57bf661614ee421840059870 243 Gene3D G3DSA:2.40.50.620 32 97 1.3E-25 T 13-10-2018 Astex_0945 d26bc10b57bf661614ee421840059870 243 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 208 35.915 T 13-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0090 c5ae91aa17b1df764e859930c0f9d3f4 827 Pfam PF01580 FtsK/SpoIIIE family 437 655 5.6E-68 T 13-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 Astex_0090 c5ae91aa17b1df764e859930c0f9d3f4 827 Gene3D G3DSA:1.10.10.10 755 820 3.2E-25 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_0090 c5ae91aa17b1df764e859930c0f9d3f4 827 Gene3D G3DSA:3.30.980.40 330 433 2.7E-28 T 13-10-2018 Astex_0090 c5ae91aa17b1df764e859930c0f9d3f4 827 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 29 182 6.3E-19 T 13-10-2018 IPR025199 DNA translocase FtsK, 4TM region Astex_0090 c5ae91aa17b1df764e859930c0f9d3f4 827 SUPERFAMILY SSF46785 759 823 2.58E-20 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_0090 c5ae91aa17b1df764e859930c0f9d3f4 827 SUPERFAMILY SSF52540 453 725 3.7E-48 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0090 c5ae91aa17b1df764e859930c0f9d3f4 827 Gene3D G3DSA:3.40.50.300 434 740 3.2E-113 T 13-10-2018 Astex_0090 c5ae91aa17b1df764e859930c0f9d3f4 827 Pfam PF09397 Ftsk gamma domain 761 821 7.0E-26 T 13-10-2018 IPR018541 FtsK gamma domain Astex_0090 c5ae91aa17b1df764e859930c0f9d3f4 827 SMART SM00843 759 824 4.6E-36 T 13-10-2018 IPR018541 FtsK gamma domain Astex_0238 8e2f0c9dec0c9ad5bc4e9a395eddcbdc 512 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 282 509 3.0E-80 T 13-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 Astex_0238 8e2f0c9dec0c9ad5bc4e9a395eddcbdc 512 Pfam PF00364 Biotin-requiring enzyme 113 185 8.5E-21 T 13-10-2018 IPR000089 Biotin/lipoyl attachment Astex_0238 8e2f0c9dec0c9ad5bc4e9a395eddcbdc 512 Pfam PF00364 Biotin-requiring enzyme 3 75 7.5E-21 T 13-10-2018 IPR000089 Biotin/lipoyl attachment Astex_0238 8e2f0c9dec0c9ad5bc4e9a395eddcbdc 512 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 113 512 2.6E-171 T 13-10-2018 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 Astex_0238 8e2f0c9dec0c9ad5bc4e9a395eddcbdc 512 Pfam PF02817 e3 binding domain 218 252 2.4E-9 T 13-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 Astex_0238 8e2f0c9dec0c9ad5bc4e9a395eddcbdc 512 Gene3D G3DSA:2.40.50.100 107 210 5.6E-24 T 13-10-2018 Astex_0238 8e2f0c9dec0c9ad5bc4e9a395eddcbdc 512 Gene3D G3DSA:2.40.50.100 1 100 6.2E-26 T 13-10-2018 Astex_0238 8e2f0c9dec0c9ad5bc4e9a395eddcbdc 512 Gene3D G3DSA:4.10.320.10 211 257 1.0E-10 T 13-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 Astex_0238 8e2f0c9dec0c9ad5bc4e9a395eddcbdc 512 SUPERFAMILY SSF52777 282 511 4.89E-87 T 13-10-2018 Astex_0238 8e2f0c9dec0c9ad5bc4e9a395eddcbdc 512 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 26 55 - T 13-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 Astex_0238 8e2f0c9dec0c9ad5bc4e9a395eddcbdc 512 Gene3D G3DSA:3.30.559.10 281 512 1.0E-92 T 13-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 Astex_0238 8e2f0c9dec0c9ad5bc4e9a395eddcbdc 512 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 136 165 - T 13-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 Astex_0238 8e2f0c9dec0c9ad5bc4e9a395eddcbdc 512 SUPERFAMILY SSF51230 3 95 1.14E-27 T 13-10-2018 IPR011053 Single hybrid motif Astex_0238 8e2f0c9dec0c9ad5bc4e9a395eddcbdc 512 SUPERFAMILY SSF51230 112 203 8.9E-25 T 13-10-2018 IPR011053 Single hybrid motif Astex_0238 8e2f0c9dec0c9ad5bc4e9a395eddcbdc 512 SUPERFAMILY SSF47005 212 256 5.23E-9 T 13-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 Astex_3705 3febae09e9ab96329a8a2c66b6183d2b 337 Pfam PF00756 Putative esterase 40 309 1.5E-24 T 13-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 Astex_3705 3febae09e9ab96329a8a2c66b6183d2b 337 SUPERFAMILY SSF53474 40 327 6.54E-42 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_0855 25ad43e281299e3eba03fd0bd80e17df 339 SUPERFAMILY SSF111369 72 228 1.03E-18 T 13-10-2018 Astex_0855 25ad43e281299e3eba03fd0bd80e17df 339 Pfam PF13533 Biotin-lipoyl like 72 119 9.4E-9 T 13-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain Astex_0855 25ad43e281299e3eba03fd0bd80e17df 339 Gene3D G3DSA:1.10.287.470 105 196 4.4E-41 T 13-10-2018 Astex_0855 25ad43e281299e3eba03fd0bd80e17df 339 Gene3D G3DSA:2.40.50.100 73 232 4.4E-41 T 13-10-2018 Astex_0855 25ad43e281299e3eba03fd0bd80e17df 339 Pfam PF13437 HlyD family secretion protein 197 305 1.2E-5 T 13-10-2018 Astex_0855 25ad43e281299e3eba03fd0bd80e17df 339 Gene3D G3DSA:2.40.30.170 234 311 4.4E-41 T 13-10-2018 Astex_0855 25ad43e281299e3eba03fd0bd80e17df 339 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 74 320 7.8E-29 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 Astex_2866 f0d357f18acbbc870aed251e1d997d37 809 Pfam PF01301 Glycosyl hydrolases family 35 61 406 1.2E-54 T 13-10-2018 IPR031330 Glycoside hydrolase 35, catalytic domain KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_2866 f0d357f18acbbc870aed251e1d997d37 809 SUPERFAMILY SSF51445 52 401 9.78E-64 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_2866 f0d357f18acbbc870aed251e1d997d37 809 PRINTS PR00742 Glycosyl hydrolase family 35 signature 85 103 1.5E-21 T 13-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_2866 f0d357f18acbbc870aed251e1d997d37 809 PRINTS PR00742 Glycosyl hydrolase family 35 signature 140 159 1.5E-21 T 13-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_2866 f0d357f18acbbc870aed251e1d997d37 809 PRINTS PR00742 Glycosyl hydrolase family 35 signature 193 208 1.5E-21 T 13-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_2866 f0d357f18acbbc870aed251e1d997d37 809 PRINTS PR00742 Glycosyl hydrolase family 35 signature 376 392 1.5E-21 T 13-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_2866 f0d357f18acbbc870aed251e1d997d37 809 PRINTS PR00742 Glycosyl hydrolase family 35 signature 64 81 1.5E-21 T 13-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_2866 f0d357f18acbbc870aed251e1d997d37 809 ProSitePatterns PS01182 Glycosyl hydrolases family 35 putative active site. 195 207 - T 13-10-2018 IPR019801 Glycoside hydrolase, family 35, conserved site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_2866 f0d357f18acbbc870aed251e1d997d37 809 Gene3D G3DSA:3.20.20.80 51 412 4.9E-95 T 13-10-2018 Astex_2305 315e16c65b2cc97be5c39a229db5ffca 310 SUPERFAMILY SSF49899 70 308 2.44E-50 T 13-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily Astex_2305 315e16c65b2cc97be5c39a229db5ffca 310 Gene3D G3DSA:2.60.120.200 60 310 5.3E-51 T 13-10-2018 Astex_2305 315e16c65b2cc97be5c39a229db5ffca 310 Pfam PF00722 Glycosyl hydrolases family 16 123 304 2.3E-20 T 13-10-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 Astex_1046 daf4c3e983b5a7880aaa643f528d1aa8 116 Gene3D G3DSA:2.60.40.1220 22 115 1.7E-12 T 13-10-2018 Astex_1046 daf4c3e983b5a7880aaa643f528d1aa8 116 SUPERFAMILY SSF81296 21 109 4.62E-13 T 13-10-2018 IPR014756 Immunoglobulin E-set Astex_1046 daf4c3e983b5a7880aaa643f528d1aa8 116 Pfam PF04234 CopC domain 22 107 1.4E-13 T 13-10-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 Astex_1405 aaccf4a73d791111552f9e472fa9fee0 410 SUPERFAMILY SSF53335 146 409 3.38E-74 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Astex_1405 aaccf4a73d791111552f9e472fa9fee0 410 Pfam PF02353 Mycolic acid cyclopropane synthetase 138 405 2.4E-80 T 13-10-2018 Astex_1405 aaccf4a73d791111552f9e472fa9fee0 410 Gene3D G3DSA:3.40.50.150 144 410 2.3E-95 T 13-10-2018 Astex_1405 aaccf4a73d791111552f9e472fa9fee0 410 PIRSF PIRSF003085 23 410 6.8E-122 T 13-10-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 Astex_3508 68c4924c10dc9fab5ad323328bdba996 306 SMART SM00065 32 173 2.8E-4 T 13-10-2018 IPR003018 GAF domain GO:0005515 Astex_3508 68c4924c10dc9fab5ad323328bdba996 306 Pfam PF08447 PAS fold 208 294 5.0E-18 T 13-10-2018 IPR013655 PAS fold-3 GO:0005515 Astex_3508 68c4924c10dc9fab5ad323328bdba996 306 Pfam PF01590 GAF domain 37 161 6.6E-12 T 13-10-2018 IPR003018 GAF domain GO:0005515 Astex_3508 68c4924c10dc9fab5ad323328bdba996 306 SMART SM00086 259 301 7.4E-7 T 13-10-2018 IPR001610 PAC motif Astex_3508 68c4924c10dc9fab5ad323328bdba996 306 SUPERFAMILY SSF55781 37 164 7.41E-24 T 13-10-2018 Astex_3508 68c4924c10dc9fab5ad323328bdba996 306 Gene3D G3DSA:3.30.450.40 10 175 3.4E-19 T 13-10-2018 IPR029016 GAF-like domain superfamily Astex_3508 68c4924c10dc9fab5ad323328bdba996 306 SUPERFAMILY SSF55785 194 302 4.01E-19 T 13-10-2018 IPR035965 PAS domain superfamily Astex_3508 68c4924c10dc9fab5ad323328bdba996 306 Gene3D G3DSA:3.30.450.20 180 252 4.9E-19 T 13-10-2018 Astex_3508 68c4924c10dc9fab5ad323328bdba996 306 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 183 304 7.1E-8 T 13-10-2018 IPR000014 PAS domain Astex_3508 68c4924c10dc9fab5ad323328bdba996 306 Gene3D G3DSA:2.10.70.100 256 303 1.9E-13 T 13-10-2018 Astex_0053 ce8cf0116ed13bd5c464a1b9ab6fce83 362 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 19 356 4.0E-87 T 13-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 Astex_0053 ce8cf0116ed13bd5c464a1b9ab6fce83 362 Gene3D G3DSA:3.30.390.60 143 244 3.1E-31 T 13-10-2018 IPR023120 Winged helix-turn-helix transcription repressor, HrcA, inserted dimerising domain superfamily Astex_0053 ce8cf0116ed13bd5c464a1b9ab6fce83 362 SUPERFAMILY SSF46785 17 98 3.56E-16 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_0053 ce8cf0116ed13bd5c464a1b9ab6fce83 362 Gene3D G3DSA:3.30.450.40 122 354 3.1E-31 T 13-10-2018 IPR029016 GAF-like domain superfamily Astex_0053 ce8cf0116ed13bd5c464a1b9ab6fce83 362 Gene3D G3DSA:1.10.10.10 7 99 4.9E-27 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_0053 ce8cf0116ed13bd5c464a1b9ab6fce83 362 SUPERFAMILY SSF55781 87 359 2.55E-54 T 13-10-2018 Astex_0053 ce8cf0116ed13bd5c464a1b9ab6fce83 362 Pfam PF01628 HrcA protein C terminal domain 119 343 3.3E-54 T 13-10-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 Astex_0053 ce8cf0116ed13bd5c464a1b9ab6fce83 362 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 17 350 28.259 T 13-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 Astex_0053 ce8cf0116ed13bd5c464a1b9ab6fce83 362 PIRSF PIRSF005485 15 361 1.7E-100 T 13-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 Astex_3818 8c5f3838bcc344bec8ef174e5abf7baf 110 SUPERFAMILY SSF46785 4 93 1.19E-21 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_3818 8c5f3838bcc344bec8ef174e5abf7baf 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 1.6E-8 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Astex_3818 8c5f3838bcc344bec8ef174e5abf7baf 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 1.6E-8 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Astex_3818 8c5f3838bcc344bec8ef174e5abf7baf 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 1.6E-8 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Astex_3818 8c5f3838bcc344bec8ef174e5abf7baf 110 SMART SM00418 8 89 1.1E-13 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Astex_3818 8c5f3838bcc344bec8ef174e5abf7baf 110 Pfam PF12840 Helix-turn-helix domain 8 69 2.9E-15 T 13-10-2018 Astex_3818 8c5f3838bcc344bec8ef174e5abf7baf 110 Gene3D G3DSA:1.10.10.10 2 96 1.7E-19 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_0980 76d32c74d066f84f2a700dab0944fa1b 192 Pfam PF09335 SNARE associated Golgi protein 52 154 2.8E-11 T 13-10-2018 IPR032816 SNARE associated Golgi protein Astex_3806 e0159cc46e8638b15226cf895ef90d23 324 Pfam PF00929 Exonuclease 73 227 1.4E-14 T 13-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III Astex_3806 e0159cc46e8638b15226cf895ef90d23 324 SUPERFAMILY SSF53098 72 229 7.99E-33 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily Astex_3806 e0159cc46e8638b15226cf895ef90d23 324 Gene3D G3DSA:3.30.420.10 73 249 3.3E-25 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Astex_3806 e0159cc46e8638b15226cf895ef90d23 324 SMART SM00479 73 236 1.8E-7 T 13-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III Astex_2352 6c5b7b5e996a20348e052e625cbaa096 632 SMART SM00400 34 88 5.4E-21 T 13-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 Astex_2352 6c5b7b5e996a20348e052e625cbaa096 632 Pfam PF13155 Toprim-like 264 351 4.8E-14 T 13-10-2018 Astex_2352 6c5b7b5e996a20348e052e625cbaa096 632 Hamap MF_00974 DNA primase [dnaG]. 2 621 23.448 T 13-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 Astex_2352 6c5b7b5e996a20348e052e625cbaa096 632 Pfam PF08275 DNA primase catalytic core, N-terminal domain 123 250 1.8E-40 T 13-10-2018 IPR013264 DNA primase, catalytic core, N-terminal Astex_2352 6c5b7b5e996a20348e052e625cbaa096 632 Gene3D G3DSA:3.90.580.10 1 99 1.4E-30 T 13-10-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 Astex_2352 6c5b7b5e996a20348e052e625cbaa096 632 SUPERFAMILY SSF56731 112 423 1.44E-89 T 13-10-2018 Astex_2352 6c5b7b5e996a20348e052e625cbaa096 632 Gene3D G3DSA:3.40.1360.10 240 368 3.0E-33 T 13-10-2018 Astex_2352 6c5b7b5e996a20348e052e625cbaa096 632 Pfam PF01807 CHC2 zinc finger 5 98 8.3E-27 T 13-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 Astex_2352 6c5b7b5e996a20348e052e625cbaa096 632 Gene3D G3DSA:3.90.980.10 105 239 1.6E-38 T 13-10-2018 IPR037068 DNA primase, catalytic core, N-terminal domain superfamily Astex_2352 6c5b7b5e996a20348e052e625cbaa096 632 SUPERFAMILY SSF57783 2 98 1.58E-29 T 13-10-2018 Astex_2352 6c5b7b5e996a20348e052e625cbaa096 632 PIRSF PIRSF002811 1 617 2.7E-125 T 13-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 Astex_2352 6c5b7b5e996a20348e052e625cbaa096 632 TIGRFAM TIGR01391 dnaG: DNA primase 3 417 8.4E-131 T 13-10-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 Astex_2352 6c5b7b5e996a20348e052e625cbaa096 632 SMART SM00493 261 331 8.2E-13 T 13-10-2018 IPR006171 TOPRIM domain Astex_1763 3b1b56c8e443e906945647105658519b 463 Gene3D G3DSA:3.40.50.620 1 313 1.5E-118 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Astex_1763 3b1b56c8e443e906945647105658519b 463 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 64 73 2.9E-29 T 13-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 Astex_1763 3b1b56c8e443e906945647105658519b 463 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 2.9E-29 T 13-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 Astex_1763 3b1b56c8e443e906945647105658519b 463 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 224 245 2.9E-29 T 13-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 Astex_1763 3b1b56c8e443e906945647105658519b 463 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 193 211 2.9E-29 T 13-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 Astex_1763 3b1b56c8e443e906945647105658519b 463 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 3 460 4.7E-145 T 13-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 Astex_1763 3b1b56c8e443e906945647105658519b 463 Pfam PF09190 DALR domain 348 405 6.1E-7 T 13-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 Astex_1763 3b1b56c8e443e906945647105658519b 463 SUPERFAMILY SSF52374 4 321 1.1E-90 T 13-10-2018 Astex_1763 3b1b56c8e443e906945647105658519b 463 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 17 320 4.3E-114 T 13-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 Astex_1763 3b1b56c8e443e906945647105658519b 463 SMART SM00840 347 405 2.2E-10 T 13-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 Astex_1763 3b1b56c8e443e906945647105658519b 463 SUPERFAMILY SSF47323 324 461 7.06E-27 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Astex_1763 3b1b56c8e443e906945647105658519b 463 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 462 35.625 T 13-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 Astex_1763 3b1b56c8e443e906945647105658519b 463 Gene3D G3DSA:1.20.120.640 315 462 1.0E-31 T 13-10-2018 Astex_0488 1c9fae28e4827cec38b1c38154d684f6 557 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 243 256 - T 13-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Astex_0488 1c9fae28e4827cec38b1c38154d684f6 557 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 40 56 - T 13-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Astex_0488 1c9fae28e4827cec38b1c38154d684f6 557 SUPERFAMILY SSF110921 452 556 3.66E-29 T 13-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Astex_0488 1c9fae28e4827cec38b1c38154d684f6 557 Gene3D G3DSA:3.20.20.70 13 378 4.5E-152 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_0488 1c9fae28e4827cec38b1c38154d684f6 557 Pfam PF08502 LeuA allosteric (dimerisation) domain 424 556 6.0E-22 T 13-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Astex_0488 1c9fae28e4827cec38b1c38154d684f6 557 SUPERFAMILY SSF89000 390 439 6.28E-15 T 13-10-2018 Astex_0488 1c9fae28e4827cec38b1c38154d684f6 557 SUPERFAMILY SSF51569 22 330 2.56E-97 T 13-10-2018 Astex_0488 1c9fae28e4827cec38b1c38154d684f6 557 SMART SM00917 424 557 3.0E-28 T 13-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Astex_0488 1c9fae28e4827cec38b1c38154d684f6 557 Pfam PF00682 HMGL-like 33 313 1.0E-74 T 13-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 Astex_0488 1c9fae28e4827cec38b1c38154d684f6 557 TIGRFAM TIGR00970 leuA_yeast: 2-isopropylmalate synthase 6 555 1.6E-242 T 13-10-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Astex_0488 1c9fae28e4827cec38b1c38154d684f6 557 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 7 557 52.405 T 13-10-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Astex_0488 1c9fae28e4827cec38b1c38154d684f6 557 Gene3D G3DSA:3.30.160.270 379 556 3.6E-58 T 13-10-2018 Astex_2725 b8e05833d82db1b16afe51a34847a9d6 613 PRINTS PR00742 Glycosyl hydrolase family 35 signature 323 339 2.5E-47 T 13-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_2725 b8e05833d82db1b16afe51a34847a9d6 613 PRINTS PR00742 Glycosyl hydrolase family 35 signature 118 137 2.5E-47 T 13-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_2725 b8e05833d82db1b16afe51a34847a9d6 613 PRINTS PR00742 Glycosyl hydrolase family 35 signature 259 274 2.5E-47 T 13-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_2725 b8e05833d82db1b16afe51a34847a9d6 613 PRINTS PR00742 Glycosyl hydrolase family 35 signature 522 536 2.5E-47 T 13-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_2725 b8e05833d82db1b16afe51a34847a9d6 613 PRINTS PR00742 Glycosyl hydrolase family 35 signature 42 59 2.5E-47 T 13-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_2725 b8e05833d82db1b16afe51a34847a9d6 613 PRINTS PR00742 Glycosyl hydrolase family 35 signature 63 81 2.5E-47 T 13-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_2725 b8e05833d82db1b16afe51a34847a9d6 613 PRINTS PR00742 Glycosyl hydrolase family 35 signature 173 188 2.5E-47 T 13-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_2725 b8e05833d82db1b16afe51a34847a9d6 613 PRINTS PR00742 Glycosyl hydrolase family 35 signature 548 564 2.5E-47 T 13-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_2725 b8e05833d82db1b16afe51a34847a9d6 613 PIRSF PIRSF006336 11 601 1.6E-170 T 13-10-2018 IPR026283 Beta-galactosidase 1-like GO:0004565 Astex_2725 b8e05833d82db1b16afe51a34847a9d6 613 Gene3D G3DSA:3.20.20.80 26 299 5.9E-96 T 13-10-2018 Astex_2725 b8e05833d82db1b16afe51a34847a9d6 613 ProSitePatterns PS01182 Glycosyl hydrolases family 35 putative active site. 175 187 - T 13-10-2018 IPR019801 Glycoside hydrolase, family 35, conserved site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_2725 b8e05833d82db1b16afe51a34847a9d6 613 Gene3D G3DSA:2.60.120.260 378 507 3.8E-93 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_2725 b8e05833d82db1b16afe51a34847a9d6 613 Pfam PF01301 Glycosyl hydrolases family 35 38 354 4.0E-102 T 13-10-2018 IPR031330 Glycoside hydrolase 35, catalytic domain KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_2725 b8e05833d82db1b16afe51a34847a9d6 613 SUPERFAMILY SSF49785 468 596 8.38E-28 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_2725 b8e05833d82db1b16afe51a34847a9d6 613 Gene3D G3DSA:2.60.120.260 300 590 3.8E-93 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_2725 b8e05833d82db1b16afe51a34847a9d6 613 SUPERFAMILY SSF51445 31 356 8.62E-88 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_1672 99e92525e0eb6536a810431ffb6d115f 552 ProSitePatterns PS01134 FtsZ protein signature 1. 47 81 - T 13-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 Astex_1672 99e92525e0eb6536a810431ffb6d115f 552 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 12 351 37.96 T 13-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 Astex_1672 99e92525e0eb6536a810431ffb6d115f 552 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 16 177 7.8E-43 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 Astex_1672 99e92525e0eb6536a810431ffb6d115f 552 SMART SM00865 210 328 9.8E-59 T 13-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 Astex_1672 99e92525e0eb6536a810431ffb6d115f 552 Pfam PF12327 FtsZ family, C-terminal domain 225 320 3.2E-38 T 13-10-2018 IPR024757 Cell division protein FtsZ, C-terminal Astex_1672 99e92525e0eb6536a810431ffb6d115f 552 Gene3D G3DSA:3.40.50.1440 7 223 2.8E-78 T 13-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 Astex_1672 99e92525e0eb6536a810431ffb6d115f 552 ProSitePatterns PS01135 FtsZ protein signature 2. 100 121 - T 13-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 Astex_1672 99e92525e0eb6536a810431ffb6d115f 552 SUPERFAMILY SSF55307 207 322 1.99E-43 T 13-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 Astex_1672 99e92525e0eb6536a810431ffb6d115f 552 SMART SM00864 16 208 5.5E-108 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 Astex_1672 99e92525e0eb6536a810431ffb6d115f 552 Gene3D G3DSA:3.30.1330.20 224 331 2.7E-39 T 13-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 Astex_1672 99e92525e0eb6536a810431ffb6d115f 552 SUPERFAMILY SSF52490 15 211 2.09E-70 T 13-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 Astex_1672 99e92525e0eb6536a810431ffb6d115f 552 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 14 328 3.9E-125 T 13-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 Astex_1672 99e92525e0eb6536a810431ffb6d115f 552 PRINTS PR00423 Cell division protein FtsZ signature 129 150 2.9E-50 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 Astex_1672 99e92525e0eb6536a810431ffb6d115f 552 PRINTS PR00423 Cell division protein FtsZ signature 101 121 2.9E-50 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 Astex_1672 99e92525e0eb6536a810431ffb6d115f 552 PRINTS PR00423 Cell division protein FtsZ signature 192 214 2.9E-50 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 Astex_1672 99e92525e0eb6536a810431ffb6d115f 552 PRINTS PR00423 Cell division protein FtsZ signature 215 236 2.9E-50 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 Astex_0655 8b4f1c63faed9826987fb2b986aa9e7f 886 SMART SM00388 654 721 2.9E-4 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_0655 8b4f1c63faed9826987fb2b986aa9e7f 886 PRINTS PR00344 Bacterial sensor protein C-terminal signature 802 816 8.4E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_0655 8b4f1c63faed9826987fb2b986aa9e7f 886 PRINTS PR00344 Bacterial sensor protein C-terminal signature 843 861 8.4E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_0655 8b4f1c63faed9826987fb2b986aa9e7f 886 PRINTS PR00344 Bacterial sensor protein C-terminal signature 867 880 8.4E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_0655 8b4f1c63faed9826987fb2b986aa9e7f 886 SUPERFAMILY SSF47384 650 722 5.1E-9 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Astex_0655 8b4f1c63faed9826987fb2b986aa9e7f 886 Pfam PF13493 Domain of unknown function (DUF4118) 401 506 1.9E-29 T 13-10-2018 IPR025201 Sensor protein KdpD, transmembrane domain Astex_0655 8b4f1c63faed9826987fb2b986aa9e7f 886 Gene3D G3DSA:3.40.50.300 23 233 9.3E-94 T 13-10-2018 Astex_0655 8b4f1c63faed9826987fb2b986aa9e7f 886 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 25 234 2.0E-91 T 13-10-2018 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 Astex_0655 8b4f1c63faed9826987fb2b986aa9e7f 886 Gene3D G3DSA:3.30.565.10 731 884 1.0E-34 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_0655 8b4f1c63faed9826987fb2b986aa9e7f 886 SUPERFAMILY SSF52540 20 148 1.36E-7 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0655 8b4f1c63faed9826987fb2b986aa9e7f 886 SUPERFAMILY SSF55874 711 883 3.93E-35 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_0655 8b4f1c63faed9826987fb2b986aa9e7f 886 SUPERFAMILY SSF52402 254 366 8.12E-7 T 13-10-2018 Astex_0655 8b4f1c63faed9826987fb2b986aa9e7f 886 Gene3D G3DSA:1.20.120.620 398 499 2.6E-30 T 13-10-2018 IPR038318 KdpD, transmembrane domain superfamily Astex_0655 8b4f1c63faed9826987fb2b986aa9e7f 886 Gene3D G3DSA:3.30.450.40 511 646 1.1E-23 T 13-10-2018 IPR029016 GAF-like domain superfamily Astex_0655 8b4f1c63faed9826987fb2b986aa9e7f 886 Gene3D G3DSA:1.10.287.130 647 726 1.2E-10 T 13-10-2018 Astex_0655 8b4f1c63faed9826987fb2b986aa9e7f 886 SMART SM00387 765 883 2.4E-29 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_0655 8b4f1c63faed9826987fb2b986aa9e7f 886 SUPERFAMILY SSF55781 510 648 3.77E-5 T 13-10-2018 Astex_0655 8b4f1c63faed9826987fb2b986aa9e7f 886 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 769 881 2.3E-20 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_2364 6729fe55eff24cd62254087a4090c52a 98 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 47 66 - T 13-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 Astex_2364 6729fe55eff24cd62254087a4090c52a 98 SUPERFAMILY SSF47729 1 91 2.21E-31 T 13-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 Astex_2364 6729fe55eff24cd62254087a4090c52a 98 Hamap MF_00381 Integration host factor subunit beta [ihfB]. 1 94 29.997 T 13-10-2018 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 Astex_2364 6729fe55eff24cd62254087a4090c52a 98 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 7.3E-18 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Astex_2364 6729fe55eff24cd62254087a4090c52a 98 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 7.3E-18 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Astex_2364 6729fe55eff24cd62254087a4090c52a 98 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 7.3E-18 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Astex_2364 6729fe55eff24cd62254087a4090c52a 98 Pfam PF00216 Bacterial DNA-binding protein 1 91 4.8E-33 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Astex_2364 6729fe55eff24cd62254087a4090c52a 98 Gene3D G3DSA:4.10.520.10 1 94 6.8E-34 T 13-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 Astex_2364 6729fe55eff24cd62254087a4090c52a 98 SMART SM00411 1 91 3.4E-41 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Astex_2364 6729fe55eff24cd62254087a4090c52a 98 TIGRFAM TIGR00988 hip: integration host factor, beta subunit 1 92 9.4E-42 T 13-10-2018 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 Astex_3305 6d59b3f4a2e4ab5a4dc5376b3945dcc3 589 Gene3D G3DSA:2.30.40.10 28 562 5.5E-113 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Astex_3305 6d59b3f4a2e4ab5a4dc5376b3945dcc3 589 Gene3D G3DSA:3.20.20.140 82 545 5.5E-113 T 13-10-2018 Astex_3305 6d59b3f4a2e4ab5a4dc5376b3945dcc3 589 SUPERFAMILY SSF51556 81 546 1.26E-28 T 13-10-2018 IPR032466 Metal-dependent hydrolase Astex_3305 6d59b3f4a2e4ab5a4dc5376b3945dcc3 589 Pfam PF07969 Amidohydrolase family 70 586 1.2E-78 T 13-10-2018 IPR013108 Amidohydrolase 3 Astex_3305 6d59b3f4a2e4ab5a4dc5376b3945dcc3 589 Gene3D G3DSA:3.10.310.70 100 224 5.5E-113 T 13-10-2018 Astex_3305 6d59b3f4a2e4ab5a4dc5376b3945dcc3 589 SUPERFAMILY SSF51338 15 588 1.39E-26 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Astex_0744 10a6ee1eddd9a2e6de5606514f64ba52 227 Pfam PF02602 Uroporphyrinogen-III synthase HemD 16 198 4.9E-22 T 13-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Astex_0744 10a6ee1eddd9a2e6de5606514f64ba52 227 SUPERFAMILY SSF69618 4 198 1.31E-31 T 13-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Astex_0744 10a6ee1eddd9a2e6de5606514f64ba52 227 Gene3D G3DSA:3.40.50.10090 2 112 1.2E-18 T 13-10-2018 Astex_3321 1b8fd100e4b1f58c4e21266cdeec0136 571 SUPERFAMILY SSF158472 223 271 4.32E-7 T 13-10-2018 Astex_3321 1b8fd100e4b1f58c4e21266cdeec0136 571 SMART SM00304 223 276 5.4E-6 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Astex_3321 1b8fd100e4b1f58c4e21266cdeec0136 571 Gene3D G3DSA:1.10.287.950 280 570 7.7E-52 T 13-10-2018 Astex_3321 1b8fd100e4b1f58c4e21266cdeec0136 571 SMART SM00283 294 559 1.0E-33 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_3321 1b8fd100e4b1f58c4e21266cdeec0136 571 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 374 537 2.8E-31 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_3321 1b8fd100e4b1f58c4e21266cdeec0136 571 Gene3D G3DSA:1.20.1480.50 181 279 4.3E-13 T 13-10-2018 Astex_3321 1b8fd100e4b1f58c4e21266cdeec0136 571 SUPERFAMILY SSF58104 295 565 5.23E-53 T 13-10-2018 Astex_0876 5c55503a444645bc1cf79c56cf534625 348 Gene3D G3DSA:3.75.10.10 7 347 5.1E-105 T 13-10-2018 Astex_0876 5c55503a444645bc1cf79c56cf534625 348 SUPERFAMILY SSF55909 7 344 5.89E-104 T 13-10-2018 Astex_0876 5c55503a444645bc1cf79c56cf534625 348 Pfam PF04371 Porphyromonas-type peptidyl-arginine deiminase 11 344 6.6E-104 T 13-10-2018 IPR007466 Peptidyl-arginine deiminase, Porphyromonas-type GO:0004668|GO:0009446 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 Astex_2797 e277d0815a5c6cd821ac20ff3b844b8c 797 SUPERFAMILY SSF54211 590 765 7.59E-56 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Astex_2797 e277d0815a5c6cd821ac20ff3b844b8c 797 SMART SM00382 344 490 3.8E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_2797 e277d0815a5c6cd821ac20ff3b844b8c 797 Gene3D G3DSA:1.20.58.1480 118 241 2.6E-41 T 13-10-2018 Astex_2797 e277d0815a5c6cd821ac20ff3b844b8c 797 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 6 197 6.8E-37 T 13-10-2018 IPR003111 Lon, substrate-binding domain Astex_2797 e277d0815a5c6cd821ac20ff3b844b8c 797 PIRSF PIRSF001174 3 769 0.0 T 13-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 Astex_2797 e277d0815a5c6cd821ac20ff3b844b8c 797 SUPERFAMILY SSF52540 310 581 3.39E-51 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2797 e277d0815a5c6cd821ac20ff3b844b8c 797 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 671 679 - T 13-10-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 Astex_2797 e277d0815a5c6cd821ac20ff3b844b8c 797 Hamap MF_01973 Lon protease [lon]. 7 767 69.834 T 13-10-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 Astex_2797 e277d0815a5c6cd821ac20ff3b844b8c 797 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 565 767 3.5E-95 T 13-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 Astex_2797 e277d0815a5c6cd821ac20ff3b844b8c 797 Gene3D G3DSA:3.40.50.300 309 486 2.0E-61 T 13-10-2018 Astex_2797 e277d0815a5c6cd821ac20ff3b844b8c 797 TIGRFAM TIGR00763 lon: endopeptidase La 8 766 2.1E-294 T 13-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 Astex_2797 e277d0815a5c6cd821ac20ff3b844b8c 797 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 348 483 9.0E-20 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Astex_2797 e277d0815a5c6cd821ac20ff3b844b8c 797 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 721 739 8.6E-56 T 13-10-2018 Astex_2797 e277d0815a5c6cd821ac20ff3b844b8c 797 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 698 717 8.6E-56 T 13-10-2018 Astex_2797 e277d0815a5c6cd821ac20ff3b844b8c 797 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 668 687 8.6E-56 T 13-10-2018 Astex_2797 e277d0815a5c6cd821ac20ff3b844b8c 797 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 352 371 8.6E-56 T 13-10-2018 Astex_2797 e277d0815a5c6cd821ac20ff3b844b8c 797 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 590 606 8.6E-56 T 13-10-2018 Astex_2797 e277d0815a5c6cd821ac20ff3b844b8c 797 SUPERFAMILY SSF88697 6 197 8.95E-47 T 13-10-2018 IPR015947 PUA-like superfamily Astex_2797 e277d0815a5c6cd821ac20ff3b844b8c 797 SMART SM00464 6 198 4.9E-67 T 13-10-2018 IPR003111 Lon, substrate-binding domain Astex_2797 e277d0815a5c6cd821ac20ff3b844b8c 797 Gene3D G3DSA:2.30.130.40 5 111 1.1E-33 T 13-10-2018 Astex_2797 e277d0815a5c6cd821ac20ff3b844b8c 797 Gene3D G3DSA:3.30.230.10 588 774 1.2E-80 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Astex_2797 e277d0815a5c6cd821ac20ff3b844b8c 797 Gene3D G3DSA:1.10.8.60 487 579 8.4E-26 T 13-10-2018 Astex_1600 79f900c7b9746df7693094acfb0d9cfd 794 SMART SM01217 714 783 8.0E-37 T 13-10-2018 IPR026891 Fibronectin type III-like domain Astex_1600 79f900c7b9746df7693094acfb0d9cfd 794 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 53 398 7.6E-74 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_1600 79f900c7b9746df7693094acfb0d9cfd 794 Gene3D G3DSA:2.60.40.10 680 794 4.6E-39 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_1600 79f900c7b9746df7693094acfb0d9cfd 794 Gene3D G3DSA:3.20.20.300 41 421 5.4E-117 T 13-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 Astex_1600 79f900c7b9746df7693094acfb0d9cfd 794 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 437 677 4.1E-53 T 13-10-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 Astex_1600 79f900c7b9746df7693094acfb0d9cfd 794 SUPERFAMILY SSF51445 32 435 1.16E-103 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_1600 79f900c7b9746df7693094acfb0d9cfd 794 PRINTS PR00133 Glycosyl hydrolase family 3 signature 318 336 4.0E-21 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_1600 79f900c7b9746df7693094acfb0d9cfd 794 PRINTS PR00133 Glycosyl hydrolase family 3 signature 247 263 4.0E-21 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_1600 79f900c7b9746df7693094acfb0d9cfd 794 PRINTS PR00133 Glycosyl hydrolase family 3 signature 140 156 4.0E-21 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_1600 79f900c7b9746df7693094acfb0d9cfd 794 PRINTS PR00133 Glycosyl hydrolase family 3 signature 163 182 4.0E-21 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_1600 79f900c7b9746df7693094acfb0d9cfd 794 PRINTS PR00133 Glycosyl hydrolase family 3 signature 209 225 4.0E-21 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_1600 79f900c7b9746df7693094acfb0d9cfd 794 SUPERFAMILY SSF52279 437 680 3.53E-49 T 13-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 Astex_1600 79f900c7b9746df7693094acfb0d9cfd 794 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 318 335 - T 13-10-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 Astex_1600 79f900c7b9746df7693094acfb0d9cfd 794 Gene3D G3DSA:3.40.50.1700 422 679 8.8E-71 T 13-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 Astex_1600 79f900c7b9746df7693094acfb0d9cfd 794 Pfam PF14310 Fibronectin type III-like domain 714 783 1.7E-25 T 13-10-2018 IPR026891 Fibronectin type III-like domain Astex_2254 b3076458ac7827920aa9e810a4852d85 294 Pfam PF13566 Domain of unknown function (DUF4130 96 253 6.8E-44 T 13-10-2018 IPR025404 Domain of unknown function DUF4130 Astex_2254 b3076458ac7827920aa9e810a4852d85 294 TIGRFAM TIGR03915 SAM_7_link_chp: probable DNA metabolism protein 7 254 2.5E-67 T 13-10-2018 IPR023875 DNA metabolism protein, putative Astex_1779 192659055c1775c1771e2820df2ffca5 266 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 37 50 - T 13-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Astex_1779 192659055c1775c1771e2820df2ffca5 266 SUPERFAMILY SSF51717 6 265 9.68E-91 T 13-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Astex_1779 192659055c1775c1771e2820df2ffca5 266 Gene3D G3DSA:3.20.20.20 2 266 3.0E-99 T 13-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Astex_1779 192659055c1775c1771e2820df2ffca5 266 Pfam PF00809 Pterin binding enzyme 8 250 2.1E-78 T 13-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Astex_1779 192659055c1775c1771e2820df2ffca5 266 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 7 22 - T 13-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Astex_1779 192659055c1775c1771e2820df2ffca5 266 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 7 264 8.2E-94 T 13-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 Astex_3222 2e2d653dc46a2eb40c8acc46c6f7a81d 228 Gene3D G3DSA:3.40.50.300 2 226 7.1E-71 T 13-10-2018 Astex_3222 2e2d653dc46a2eb40c8acc46c6f7a81d 228 SMART SM00382 32 219 2.6E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_3222 2e2d653dc46a2eb40c8acc46c6f7a81d 228 SUPERFAMILY SSF52540 3 221 3.33E-70 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_3222 2e2d653dc46a2eb40c8acc46c6f7a81d 228 Pfam PF00005 ABC transporter 23 171 3.0E-36 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_2653 746ebfe34296463744b5ddd25bcea28e 485 SMART SM00116 94 143 6.3E-10 T 13-10-2018 IPR000644 CBS domain Astex_2653 746ebfe34296463744b5ddd25bcea28e 485 SMART SM00116 156 204 0.012 T 13-10-2018 IPR000644 CBS domain Astex_2653 746ebfe34296463744b5ddd25bcea28e 485 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 293 305 - T 13-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 Astex_2653 746ebfe34296463744b5ddd25bcea28e 485 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 6 453 2.2E-189 T 13-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 Astex_2653 746ebfe34296463744b5ddd25bcea28e 485 PIRSF PIRSF000130 1 485 8.4E-202 T 13-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 Astex_2653 746ebfe34296463744b5ddd25bcea28e 485 Pfam PF00571 CBS domain 91 139 1.9E-11 T 13-10-2018 IPR000644 CBS domain Astex_2653 746ebfe34296463744b5ddd25bcea28e 485 Pfam PF00571 CBS domain 149 199 0.0022 T 13-10-2018 IPR000644 CBS domain Astex_2653 746ebfe34296463744b5ddd25bcea28e 485 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 6 485 81.819 T 13-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 Astex_2653 746ebfe34296463744b5ddd25bcea28e 485 SMART SM01240 5 472 0.0 T 13-10-2018 Astex_2653 746ebfe34296463744b5ddd25bcea28e 485 SUPERFAMILY SSF54631 61 202 3.54E-28 T 13-10-2018 Astex_2653 746ebfe34296463744b5ddd25bcea28e 485 Gene3D G3DSA:3.20.20.70 1 485 3.2E-213 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_2653 746ebfe34296463744b5ddd25bcea28e 485 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 6 472 2.2E-160 T 13-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 Astex_2653 746ebfe34296463744b5ddd25bcea28e 485 SUPERFAMILY SSF51412 3 476 1.44E-125 T 13-10-2018 Astex_3476 ad3c3875e5ade5bf6bf43cceaca573b7 319 PIRSF PIRSF018266 1 315 5.9E-66 T 13-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component Astex_3476 ad3c3875e5ade5bf6bf43cceaca573b7 319 Gene3D G3DSA:2.60.120.1440 102 239 1.1E-23 T 13-10-2018 Astex_3476 ad3c3875e5ade5bf6bf43cceaca573b7 319 Pfam PF16220 Domain of unknown function (DUF4880) 11 50 5.0E-10 T 13-10-2018 IPR032623 FecR, N-terminal Astex_3476 ad3c3875e5ade5bf6bf43cceaca573b7 319 Pfam PF04773 FecR protein 111 203 1.2E-20 T 13-10-2018 IPR006860 FecR protein Astex_1572 f5abe330725ee21469e0cc6168da9ea2 255 Pfam PF02562 PhoH-like protein 54 252 8.8E-80 T 13-10-2018 IPR003714 PhoH-like protein GO:0005524 Astex_1572 f5abe330725ee21469e0cc6168da9ea2 255 Gene3D G3DSA:3.40.50.300 50 254 2.0E-67 T 13-10-2018 Astex_1572 f5abe330725ee21469e0cc6168da9ea2 255 SUPERFAMILY SSF52540 45 209 1.86E-34 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2540 9e65eeef2dee79b8db9a30cb201ca4e2 249 SUPERFAMILY SSF55073 100 249 1.02E-41 T 13-10-2018 IPR029787 Nucleotide cyclase Astex_2540 9e65eeef2dee79b8db9a30cb201ca4e2 249 Pfam PF00990 Diguanylate cyclase, GGDEF domain 95 248 1.6E-38 T 13-10-2018 IPR000160 GGDEF domain Astex_2540 9e65eeef2dee79b8db9a30cb201ca4e2 249 SMART SM00267 81 249 1.4E-45 T 13-10-2018 IPR000160 GGDEF domain Astex_2540 9e65eeef2dee79b8db9a30cb201ca4e2 249 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 92 249 5.7E-41 T 13-10-2018 IPR000160 GGDEF domain Astex_2540 9e65eeef2dee79b8db9a30cb201ca4e2 249 Gene3D G3DSA:3.30.70.270 91 249 6.0E-47 T 13-10-2018 Astex_0776 5f5bbdf2adb6792e0ca4d7121160f870 470 Pfam PF08443 RimK-like ATP-grasp domain 261 448 4.6E-59 T 13-10-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 Astex_0776 5f5bbdf2adb6792e0ca4d7121160f870 470 SUPERFAMILY SSF56059 261 452 1.54E-43 T 13-10-2018 Astex_0776 5f5bbdf2adb6792e0ca4d7121160f870 470 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 166 449 1.2E-77 T 13-10-2018 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 Reactome: R-HSA-70614 Astex_0776 5f5bbdf2adb6792e0ca4d7121160f870 470 Gene3D G3DSA:3.40.50.20 157 277 2.5E-32 T 13-10-2018 Astex_0776 5f5bbdf2adb6792e0ca4d7121160f870 470 Gene3D G3DSA:2.40.70.10 7 136 1.4E-30 T 13-10-2018 IPR021109 Aspartic peptidase domain superfamily Astex_0776 5f5bbdf2adb6792e0ca4d7121160f870 470 Gene3D G3DSA:3.30.1490.20 278 344 6.3E-21 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 Astex_0776 5f5bbdf2adb6792e0ca4d7121160f870 470 Pfam PF05618 Putative ATP-dependant zinc protease 9 138 1.0E-25 T 13-10-2018 Astex_0776 5f5bbdf2adb6792e0ca4d7121160f870 470 SUPERFAMILY SSF50630 9 139 1.38E-38 T 13-10-2018 IPR021109 Aspartic peptidase domain superfamily Astex_0776 5f5bbdf2adb6792e0ca4d7121160f870 470 Gene3D G3DSA:3.30.470.80 345 459 1.2E-40 T 13-10-2018 Astex_1751 369af56e05a91e18e8b916aaedadaa1b 772 SUPERFAMILY SSF52540 22 652 1.26E-170 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1751 369af56e05a91e18e8b916aaedadaa1b 772 Pfam PF00580 UvrD/REP helicase N-terminal domain 28 295 3.1E-77 T 13-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 Astex_1751 369af56e05a91e18e8b916aaedadaa1b 772 Pfam PF13361 UvrD-like helicase C-terminal domain 301 623 3.7E-60 T 13-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 Astex_1751 369af56e05a91e18e8b916aaedadaa1b 772 Gene3D G3DSA:1.10.486.10 406 560 1.3E-108 T 13-10-2018 Astex_1751 369af56e05a91e18e8b916aaedadaa1b 772 Gene3D G3DSA:1.10.10.160 130 213 3.1E-96 T 13-10-2018 IPR013986 DExx box DNA helicase domain superfamily Astex_1751 369af56e05a91e18e8b916aaedadaa1b 772 Gene3D G3DSA:3.40.50.300 304 648 1.3E-108 T 13-10-2018 Astex_1751 369af56e05a91e18e8b916aaedadaa1b 772 Gene3D G3DSA:3.40.50.300 28 296 3.1E-96 T 13-10-2018 Astex_3113 358aeb09266dbe68186049b54b6f4989 278 Gene3D G3DSA:3.40.50.12370 13 277 6.6E-21 T 13-10-2018 Astex_3113 358aeb09266dbe68186049b54b6f4989 278 SUPERFAMILY SSF52402 162 277 1.59E-12 T 13-10-2018 Astex_3113 358aeb09266dbe68186049b54b6f4989 278 SUPERFAMILY SSF52402 14 147 1.26E-5 T 13-10-2018 Astex_1266 c8647238a94e2fbd109fd3bca4719b52 337 Gene3D G3DSA:3.90.25.10 180 329 4.0E-85 T 13-10-2018 Astex_1266 c8647238a94e2fbd109fd3bca4719b52 337 Gene3D G3DSA:3.40.50.720 5 317 4.0E-85 T 13-10-2018 Astex_1266 c8647238a94e2fbd109fd3bca4719b52 337 SUPERFAMILY SSF51735 1 333 6.13E-78 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_1266 c8647238a94e2fbd109fd3bca4719b52 337 PRINTS PR01713 Nucleotide sugar epimerase signature 296 313 1.8E-22 T 13-10-2018 Astex_1266 c8647238a94e2fbd109fd3bca4719b52 337 PRINTS PR01713 Nucleotide sugar epimerase signature 257 272 1.8E-22 T 13-10-2018 Astex_1266 c8647238a94e2fbd109fd3bca4719b52 337 PRINTS PR01713 Nucleotide sugar epimerase signature 216 231 1.8E-22 T 13-10-2018 Astex_1266 c8647238a94e2fbd109fd3bca4719b52 337 PRINTS PR01713 Nucleotide sugar epimerase signature 29 45 1.8E-22 T 13-10-2018 Astex_1266 c8647238a94e2fbd109fd3bca4719b52 337 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 232 3.7E-49 T 13-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 Astex_2322 740a2e446ea63e1a503ea872663761b8 423 Pfam PF00171 Aldehyde dehydrogenase family 16 287 1.1E-11 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 Astex_2322 740a2e446ea63e1a503ea872663761b8 423 Gene3D G3DSA:3.40.309.10 233 380 4.3E-152 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 Astex_2322 740a2e446ea63e1a503ea872663761b8 423 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 329 351 - T 13-10-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 Astex_2322 740a2e446ea63e1a503ea872663761b8 423 SUPERFAMILY SSF53720 13 422 2.33E-103 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 Astex_2322 740a2e446ea63e1a503ea872663761b8 423 PIRSF PIRSF000151 6 423 3.6E-162 T 13-10-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 Astex_2322 740a2e446ea63e1a503ea872663761b8 423 Gene3D G3DSA:3.40.605.10 29 417 4.3E-152 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 Astex_2322 740a2e446ea63e1a503ea872663761b8 423 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 12 422 38.507 T 13-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 Astex_2322 740a2e446ea63e1a503ea872663761b8 423 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 21 412 6.1E-126 T 13-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 Astex_1437 89cda727ae137f2986564e519de96dff 218 Pfam PF03748 Flagellar basal body-associated protein FliL 121 217 2.6E-15 T 13-10-2018 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 Astex_1745 a6ffa3d1c735a36a7db6b098decb5fc1 505 Gene3D G3DSA:3.40.309.10 264 462 3.3E-164 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 Astex_1745 a6ffa3d1c735a36a7db6b098decb5fc1 505 SUPERFAMILY SSF53720 12 498 3.27E-163 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 Astex_1745 a6ffa3d1c735a36a7db6b098decb5fc1 505 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 293 304 - T 13-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 Astex_1745 a6ffa3d1c735a36a7db6b098decb5fc1 505 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 260 267 - T 13-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 Astex_1745 a6ffa3d1c735a36a7db6b098decb5fc1 505 Gene3D G3DSA:3.40.605.10 35 490 3.3E-164 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 Astex_1745 a6ffa3d1c735a36a7db6b098decb5fc1 505 Pfam PF00171 Aldehyde dehydrogenase family 26 493 5.6E-167 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 Astex_2114 b469c4f50d5ac97cbb1893d7899b9033 134 Gene3D G3DSA:3.40.50.12740 6 132 2.2E-34 T 13-10-2018 Astex_2114 b469c4f50d5ac97cbb1893d7899b9033 134 SUPERFAMILY SSF52172 7 124 4.27E-34 T 13-10-2018 IPR011006 CheY-like superfamily Astex_2114 b469c4f50d5ac97cbb1893d7899b9033 134 Pfam PF00072 Response regulator receiver domain 10 119 3.7E-23 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_2114 b469c4f50d5ac97cbb1893d7899b9033 134 SMART SM00448 7 119 1.7E-29 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_0286 b1a809a5fc2f4ede80a70e10ccbd6623 121 Pfam PF02261 Aspartate decarboxylase 2 109 4.3E-40 T 13-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 Astex_0286 b1a809a5fc2f4ede80a70e10ccbd6623 121 PIRSF PIRSF006246 1 120 2.3E-40 T 13-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 Astex_0286 b1a809a5fc2f4ede80a70e10ccbd6623 121 SUPERFAMILY SSF50692 2 111 2.86E-37 T 13-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily Astex_0286 b1a809a5fc2f4ede80a70e10ccbd6623 121 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 2 119 4.2E-37 T 13-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 Astex_0286 b1a809a5fc2f4ede80a70e10ccbd6623 121 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 4 89 7.0E-26 T 13-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 Astex_0286 b1a809a5fc2f4ede80a70e10ccbd6623 121 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 121 51.549 T 13-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 Astex_0286 b1a809a5fc2f4ede80a70e10ccbd6623 121 Gene3D G3DSA:2.40.40.20 1 120 8.5E-41 T 13-10-2018 Astex_3037 e6016d2e8501d7a9f5f3ed59e99e7c1e 309 SUPERFAMILY SSF117892 51 184 1.05E-41 T 13-10-2018 IPR036013 Band 7/SPFH domain superfamily Astex_3037 e6016d2e8501d7a9f5f3ed59e99e7c1e 309 Pfam PF16200 C-terminal region of band_7 238 300 5.9E-15 T 13-10-2018 IPR032435 Band 7, C-terminal extension Reactome: R-HSA-8949664 Astex_3037 e6016d2e8501d7a9f5f3ed59e99e7c1e 309 SMART SM00244 19 177 1.3E-58 T 13-10-2018 IPR001107 Band 7 domain Astex_3037 e6016d2e8501d7a9f5f3ed59e99e7c1e 309 Gene3D G3DSA:3.30.479.30 47 179 2.4E-44 T 13-10-2018 Astex_3037 e6016d2e8501d7a9f5f3ed59e99e7c1e 309 Pfam PF01145 SPFH domain / Band 7 family 23 202 6.4E-34 T 13-10-2018 IPR001107 Band 7 domain Astex_3037 e6016d2e8501d7a9f5f3ed59e99e7c1e 309 ProSitePatterns PS01270 Band 7 protein family signature. 133 161 - T 13-10-2018 IPR018080 Band 7/stomatin-like, conserved site Astex_3037 e6016d2e8501d7a9f5f3ed59e99e7c1e 309 PRINTS PR00721 Stomatin signature 129 152 6.0E-33 T 13-10-2018 IPR001972 Stomatin family GO:0016020 Astex_3037 e6016d2e8501d7a9f5f3ed59e99e7c1e 309 PRINTS PR00721 Stomatin signature 109 126 6.0E-33 T 13-10-2018 IPR001972 Stomatin family GO:0016020 Astex_3037 e6016d2e8501d7a9f5f3ed59e99e7c1e 309 PRINTS PR00721 Stomatin signature 74 95 6.0E-33 T 13-10-2018 IPR001972 Stomatin family GO:0016020 Astex_3037 e6016d2e8501d7a9f5f3ed59e99e7c1e 309 PRINTS PR00721 Stomatin signature 153 171 6.0E-33 T 13-10-2018 IPR001972 Stomatin family GO:0016020 Astex_3037 e6016d2e8501d7a9f5f3ed59e99e7c1e 309 PRINTS PR00721 Stomatin signature 172 193 6.0E-33 T 13-10-2018 IPR001972 Stomatin family GO:0016020 Astex_1220 6536daddaab192efaa0b2767d0f3f04b 430 SUPERFAMILY SSF103473 15 417 7.76E-31 T 13-10-2018 IPR036259 MFS transporter superfamily Astex_1220 6536daddaab192efaa0b2767d0f3f04b 430 Gene3D G3DSA:1.20.1250.20 213 427 9.8E-13 T 13-10-2018 Astex_1220 6536daddaab192efaa0b2767d0f3f04b 430 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 16 420 8.6E-87 T 13-10-2018 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 Astex_1220 6536daddaab192efaa0b2767d0f3f04b 430 Pfam PF13347 MFS/sugar transport protein 16 420 6.1E-87 T 13-10-2018 Astex_1220 6536daddaab192efaa0b2767d0f3f04b 430 Gene3D G3DSA:1.20.1250.20 13 205 8.0E-14 T 13-10-2018 Astex_3243 553c7d6c54ad7ae925ce05fa8048a374 318 Pfam PF13763 Domain of unknown function (DUF4167) 5 78 7.4E-32 T 13-10-2018 IPR025430 Domain of unknown function DUF4167 Astex_1959 9a21cc7a93f92b83c2a25ab30fe7a1d6 182 Gene3D G3DSA:3.40.50.12740 7 175 2.2E-28 T 13-10-2018 Astex_1959 9a21cc7a93f92b83c2a25ab30fe7a1d6 182 Pfam PF00072 Response regulator receiver domain 10 123 4.8E-22 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1959 9a21cc7a93f92b83c2a25ab30fe7a1d6 182 SUPERFAMILY SSF52172 6 144 8.25E-30 T 13-10-2018 IPR011006 CheY-like superfamily Astex_1959 9a21cc7a93f92b83c2a25ab30fe7a1d6 182 SMART SM00448 7 123 5.0E-25 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_2377 96b1117f304bbda2b12d9e2c4683c1ba 530 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 31 463 8.7E-131 T 13-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 Astex_2377 96b1117f304bbda2b12d9e2c4683c1ba 530 SUPERFAMILY SSF46785 420 501 1.5E-8 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_2377 96b1117f304bbda2b12d9e2c4683c1ba 530 Pfam PF16124 RecQ zinc-binding 368 422 7.9E-9 T 13-10-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain Astex_2377 96b1117f304bbda2b12d9e2c4683c1ba 530 Pfam PF00270 DEAD/DEAH box helicase 45 200 4.2E-18 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Astex_2377 96b1117f304bbda2b12d9e2c4683c1ba 530 SMART SM00956 429 529 3.6E-4 T 13-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 Astex_2377 96b1117f304bbda2b12d9e2c4683c1ba 530 SMART SM00487 37 235 1.0E-28 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Astex_2377 96b1117f304bbda2b12d9e2c4683c1ba 530 Gene3D G3DSA:3.40.50.300 224 356 1.2E-36 T 13-10-2018 Astex_2377 96b1117f304bbda2b12d9e2c4683c1ba 530 Pfam PF09382 RQC domain 427 529 5.1E-8 T 13-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 Astex_2377 96b1117f304bbda2b12d9e2c4683c1ba 530 Gene3D G3DSA:3.40.50.300 22 223 2.2E-76 T 13-10-2018 Astex_2377 96b1117f304bbda2b12d9e2c4683c1ba 530 Gene3D G3DSA:1.10.10.10 363 530 8.5E-25 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_2377 96b1117f304bbda2b12d9e2c4683c1ba 530 Pfam PF00271 Helicase conserved C-terminal domain 242 345 2.3E-17 T 13-10-2018 IPR001650 Helicase, C-terminal Astex_2377 96b1117f304bbda2b12d9e2c4683c1ba 530 SUPERFAMILY SSF52540 81 359 6.32E-56 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2377 96b1117f304bbda2b12d9e2c4683c1ba 530 SMART SM00490 266 347 1.3E-26 T 13-10-2018 IPR001650 Helicase, C-terminal Astex_2996 13beaee97194d85435f9813086f4350b 894 Pfam PF10150 Ribonuclease E/G family 165 435 9.3E-95 T 13-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 Astex_2996 13beaee97194d85435f9813086f4350b 894 Gene3D G3DSA:2.40.50.140 36 163 1.2E-39 T 13-10-2018 Astex_2996 13beaee97194d85435f9813086f4350b 894 Hamap MF_00970 Ribonuclease E [rne]. 2 894 30.26 T 13-10-2018 IPR028878 Ribonuclease E GO:0006396|GO:0008995 Astex_2996 13beaee97194d85435f9813086f4350b 894 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 14 468 2.3E-155 T 13-10-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 Astex_2996 13beaee97194d85435f9813086f4350b 894 SUPERFAMILY SSF50249 40 169 3.03E-15 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Astex_2996 13beaee97194d85435f9813086f4350b 894 SMART SM00316 38 163 7.6E-4 T 13-10-2018 IPR022967 RNA-binding domain, S1 Astex_2996 13beaee97194d85435f9813086f4350b 894 Gene3D G3DSA:3.40.1260.20 445 543 2.2E-21 T 13-10-2018 Astex_2926 61ee7b5611345a0c586b6110ce8e04f9 180 Pfam PF13488 Glycine zipper 48 90 1.3E-6 T 13-10-2018 IPR039567 Glycine zipper domain Astex_3406 14900c351c3da7f128fa197cd778e41d 447 SUPERFAMILY SSF46689 359 440 4.48E-7 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Astex_3406 14900c351c3da7f128fa197cd778e41d 447 SMART SM00448 6 117 5.2E-31 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_3406 14900c351c3da7f128fa197cd778e41d 447 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 234 249 - T 13-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 Astex_3406 14900c351c3da7f128fa197cd778e41d 447 Pfam PF00072 Response regulator receiver domain 9 117 1.1E-29 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_3406 14900c351c3da7f128fa197cd778e41d 447 Gene3D G3DSA:3.40.50.2300 8 147 7.9E-38 T 13-10-2018 Astex_3406 14900c351c3da7f128fa197cd778e41d 447 SUPERFAMILY SSF52172 9 193 3.98E-42 T 13-10-2018 IPR011006 CheY-like superfamily Astex_3406 14900c351c3da7f128fa197cd778e41d 447 Gene3D G3DSA:3.40.50.300 148 319 1.5E-45 T 13-10-2018 Astex_3406 14900c351c3da7f128fa197cd778e41d 447 SMART SM00382 169 311 1.1E-5 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_3406 14900c351c3da7f128fa197cd778e41d 447 Gene3D G3DSA:1.10.10.60 390 442 5.7E-8 T 13-10-2018 Astex_3406 14900c351c3da7f128fa197cd778e41d 447 SUPERFAMILY SSF52540 149 379 1.82E-51 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_3406 14900c351c3da7f128fa197cd778e41d 447 Pfam PF00158 Sigma-54 interaction domain 150 314 1.2E-47 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 Astex_3406 14900c351c3da7f128fa197cd778e41d 447 Gene3D G3DSA:1.10.8.60 320 389 3.3E-17 T 13-10-2018 Astex_2219 3487606bdb59323fa4bf7ed66dbecb9c 289 Gene3D G3DSA:2.60.120.200 53 289 1.1E-49 T 13-10-2018 Astex_2219 3487606bdb59323fa4bf7ed66dbecb9c 289 SUPERFAMILY SSF49899 47 288 3.17E-47 T 13-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily Astex_2219 3487606bdb59323fa4bf7ed66dbecb9c 289 Pfam PF00722 Glycosyl hydrolases family 16 102 282 9.1E-20 T 13-10-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 Astex_3643 dd632c79a896734cc5df73d3cbc8102b 1202 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 120 322 1.1E-62 T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Astex_3643 dd632c79a896734cc5df73d3cbc8102b 1202 SUPERFAMILY SSF160467 798 889 1.57E-17 T 13-10-2018 Astex_3643 dd632c79a896734cc5df73d3cbc8102b 1202 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 475 746 7.2E-85 T 13-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B Astex_3643 dd632c79a896734cc5df73d3cbc8102b 1202 Pfam PF00364 Biotin-requiring enzyme 1124 1198 4.5E-15 T 13-10-2018 IPR000089 Biotin/lipoyl attachment Astex_3643 dd632c79a896734cc5df73d3cbc8102b 1202 Gene3D G3DSA:2.40.100.10 879 1101 1.8E-91 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily Astex_3643 dd632c79a896734cc5df73d3cbc8102b 1202 Gene3D G3DSA:2.40.100.10 626 775 3.1E-58 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily Astex_3643 dd632c79a896734cc5df73d3cbc8102b 1202 TIGRFAM TIGR02712 urea_carbox: urea carboxylase 6 1199 0.0 T 13-10-2018 IPR014084 Urea carboxylase KEGG: 00220+3.5.1.54+6.3.4.6|KEGG: 00791+3.5.1.54+6.3.4.6|MetaCyc: PWY-5169|MetaCyc: PWY-5703 Astex_3643 dd632c79a896734cc5df73d3cbc8102b 1202 SUPERFAMILY SSF56059 87 325 4.77E-63 T 13-10-2018 Astex_3643 dd632c79a896734cc5df73d3cbc8102b 1202 SUPERFAMILY SSF51230 1125 1200 1.09E-18 T 13-10-2018 IPR011053 Single hybrid motif Astex_3643 dd632c79a896734cc5df73d3cbc8102b 1202 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 798 1018 1.1E-41 T 13-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D Astex_3643 dd632c79a896734cc5df73d3cbc8102b 1202 Gene3D G3DSA:2.40.50.100 1134 1201 7.3E-20 T 13-10-2018 Astex_3643 dd632c79a896734cc5df73d3cbc8102b 1202 SMART SM00796 796 1029 5.4E-105 T 13-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D Astex_3643 dd632c79a896734cc5df73d3cbc8102b 1202 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 156 170 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Astex_3643 dd632c79a896734cc5df73d3cbc8102b 1202 SMART SM00878 339 443 1.6E-45 T 13-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Astex_3643 dd632c79a896734cc5df73d3cbc8102b 1202 Gene3D G3DSA:3.30.470.130 1 448 2.1E-180 T 13-10-2018 Astex_3643 dd632c79a896734cc5df73d3cbc8102b 1202 Pfam PF00289 Biotin carboxylase, N-terminal domain 6 113 1.1E-44 T 13-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Astex_3643 dd632c79a896734cc5df73d3cbc8102b 1202 SUPERFAMILY SSF52440 4 116 1.58E-48 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily Astex_3643 dd632c79a896734cc5df73d3cbc8102b 1202 SUPERFAMILY SSF50891 913 1045 3.49E-26 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily Astex_3643 dd632c79a896734cc5df73d3cbc8102b 1202 SMART SM00797 474 763 1.6E-159 T 13-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B Astex_3643 dd632c79a896734cc5df73d3cbc8102b 1202 Pfam PF02785 Biotin carboxylase C-terminal domain 339 444 3.1E-32 T 13-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 Astex_3643 dd632c79a896734cc5df73d3cbc8102b 1202 Gene3D G3DSA:3.30.1360.40 780 875 1.1E-28 T 13-10-2018 Astex_3643 dd632c79a896734cc5df73d3cbc8102b 1202 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 452 768 6.8E-86 T 13-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B Astex_3643 dd632c79a896734cc5df73d3cbc8102b 1202 SUPERFAMILY SSF51246 334 445 3.35E-33 T 13-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 Astex_3643 dd632c79a896734cc5df73d3cbc8102b 1202 SUPERFAMILY SSF50891 627 749 9.86E-32 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily Astex_3643 dd632c79a896734cc5df73d3cbc8102b 1202 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 290 297 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 Astex_3000 250b4772af95765f21f880bf5493c3df 264 Pfam PF05690 Thiazole biosynthesis protein ThiG 15 259 1.4E-108 T 13-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 Astex_3000 250b4772af95765f21f880bf5493c3df 264 Gene3D G3DSA:3.20.20.70 5 264 3.7E-110 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_3000 250b4772af95765f21f880bf5493c3df 264 SUPERFAMILY SSF110399 11 250 5.89E-85 T 13-10-2018 Astex_3000 250b4772af95765f21f880bf5493c3df 264 Hamap MF_00443 Thiazole synthase [thiG]. 12 264 40.973 T 13-10-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 Astex_1512 4ad7a6a7af05845c6f490b3e8d92aed3 457 Pfam PF01474 Class-II DAHP synthetase family 5 443 3.7E-197 T 13-10-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 Astex_1512 4ad7a6a7af05845c6f490b3e8d92aed3 457 TIGRFAM TIGR01358 DAHP_synth_II: 3-deoxy-7-phosphoheptulonate synthase 5 447 1.0E-217 T 13-10-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 Astex_1512 4ad7a6a7af05845c6f490b3e8d92aed3 457 Gene3D G3DSA:3.20.20.70 186 448 8.1E-102 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_1512 4ad7a6a7af05845c6f490b3e8d92aed3 457 Gene3D G3DSA:3.20.20.70 39 185 3.2E-51 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_1512 4ad7a6a7af05845c6f490b3e8d92aed3 457 SUPERFAMILY SSF51569 3 447 5.79E-195 T 13-10-2018 Astex_3738 d7c27b149f9d00f0621c5cf6aab04cb8 760 Pfam PF05593 RHS Repeat 108 142 1.4E-4 T 13-10-2018 IPR031325 RHS repeat Astex_3738 d7c27b149f9d00f0621c5cf6aab04cb8 760 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 525 603 6.6E-24 T 13-10-2018 IPR022385 Rhs repeat-associated core GO:0097264 Astex_3738 d7c27b149f9d00f0621c5cf6aab04cb8 760 Gene3D G3DSA:2.180.10.10 238 603 7.8E-28 T 13-10-2018 Astex_3738 d7c27b149f9d00f0621c5cf6aab04cb8 760 Gene3D G3DSA:2.180.10.10 20 191 4.8E-6 T 13-10-2018 Astex_3738 d7c27b149f9d00f0621c5cf6aab04cb8 760 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 169 194 1.7E-4 T 13-10-2018 IPR006530 YD repeat Astex_3738 d7c27b149f9d00f0621c5cf6aab04cb8 760 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 242 282 4.0E-6 T 13-10-2018 IPR006530 YD repeat Astex_3738 d7c27b149f9d00f0621c5cf6aab04cb8 760 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 108 144 2.6E-5 T 13-10-2018 IPR006530 YD repeat Astex_1737 5d4d4c9d432c187900ec4563736f8dca 104 Gene3D G3DSA:1.10.1220.10 5 52 2.7E-9 T 13-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 Astex_1737 5d4d4c9d432c187900ec4563736f8dca 104 Pfam PF04221 RelB antitoxin 7 52 1.9E-10 T 13-10-2018 IPR007337 RelB antitoxin/Antitoxin DinJ Astex_2232 65bb9b64a892f7803d636424fd2ad049 861 Pfam PF07715 TonB-dependent Receptor Plug Domain 144 258 7.5E-19 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_2232 65bb9b64a892f7803d636424fd2ad049 861 Gene3D G3DSA:2.170.130.10 141 266 4.1E-27 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_2232 65bb9b64a892f7803d636424fd2ad049 861 Gene3D G3DSA:3.55.50.30 31 136 4.6E-17 T 13-10-2018 Astex_2232 65bb9b64a892f7803d636424fd2ad049 861 SMART SM00965 61 112 1.7E-4 T 13-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 Astex_2232 65bb9b64a892f7803d636424fd2ad049 861 Pfam PF00593 TonB dependent receptor 377 858 4.2E-38 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_2232 65bb9b64a892f7803d636424fd2ad049 861 SUPERFAMILY SSF56935 128 861 1.08E-78 T 13-10-2018 Astex_1909 93ce2c0e04c7f912a26e1bd8d0b0f4b6 594 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 131 141 - T 13-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Astex_1909 93ce2c0e04c7f912a26e1bd8d0b0f4b6 594 Gene3D G3DSA:3.50.30.80 384 548 4.5E-34 T 13-10-2018 Astex_1909 93ce2c0e04c7f912a26e1bd8d0b0f4b6 594 SUPERFAMILY SSF52016 384 580 1.41E-47 T 13-10-2018 Astex_1909 93ce2c0e04c7f912a26e1bd8d0b0f4b6 594 SUPERFAMILY SSF143975 29 381 2.75E-108 T 13-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Astex_1909 93ce2c0e04c7f912a26e1bd8d0b0f4b6 594 Pfam PF00920 Dehydratase family 48 574 7.7E-152 T 13-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Astex_0194 f65da5c591be17be3f79a087219a9e4e 166 SUPERFAMILY SSF52172 9 135 1.08E-36 T 13-10-2018 IPR011006 CheY-like superfamily Astex_0194 f65da5c591be17be3f79a087219a9e4e 166 Gene3D G3DSA:3.40.50.12740 8 161 3.7E-35 T 13-10-2018 Astex_0194 f65da5c591be17be3f79a087219a9e4e 166 SMART SM00448 7 123 2.4E-30 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_0194 f65da5c591be17be3f79a087219a9e4e 166 Pfam PF00072 Response regulator receiver domain 10 123 1.8E-26 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1054 83ef3d3b44b14ca2103a86963fef20c4 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 1.6E-5 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Astex_1054 83ef3d3b44b14ca2103a86963fef20c4 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 1.6E-5 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Astex_1054 83ef3d3b44b14ca2103a86963fef20c4 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 1.6E-5 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Astex_1054 83ef3d3b44b14ca2103a86963fef20c4 110 SMART SM00418 8 89 2.7E-10 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Astex_1054 83ef3d3b44b14ca2103a86963fef20c4 110 SUPERFAMILY SSF46785 5 93 1.15E-19 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_1054 83ef3d3b44b14ca2103a86963fef20c4 110 Pfam PF12840 Helix-turn-helix domain 8 69 6.3E-14 T 13-10-2018 Astex_1054 83ef3d3b44b14ca2103a86963fef20c4 110 Gene3D G3DSA:1.10.10.10 2 93 4.9E-17 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1386 eb20ff72a3383ce0ddbc5eecfcb11614 1151 SUPERFAMILY SSF56935 47 1151 2.56E-76 T 13-10-2018 Astex_1386 eb20ff72a3383ce0ddbc5eecfcb11614 1151 Pfam PF00593 TonB dependent receptor 619 1150 8.9E-31 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_1386 eb20ff72a3383ce0ddbc5eecfcb11614 1151 Gene3D G3DSA:2.170.130.10 35 182 1.5E-16 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_1386 eb20ff72a3383ce0ddbc5eecfcb11614 1151 Pfam PF07715 TonB-dependent Receptor Plug Domain 63 175 3.2E-14 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_0084 7789323f05bf99ca8d2504557baea99e 110 ProSitePatterns PS00194 Thioredoxin family active site. 25 43 - T 13-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 Astex_0084 7789323f05bf99ca8d2504557baea99e 110 Gene3D G3DSA:3.40.30.10 1 107 4.0E-38 T 13-10-2018 Astex_0084 7789323f05bf99ca8d2504557baea99e 110 PRINTS PR00421 Thioredoxin family signature 32 41 6.0E-10 T 13-10-2018 Astex_0084 7789323f05bf99ca8d2504557baea99e 110 PRINTS PR00421 Thioredoxin family signature 24 32 6.0E-10 T 13-10-2018 Astex_0084 7789323f05bf99ca8d2504557baea99e 110 PRINTS PR00421 Thioredoxin family signature 72 83 6.0E-10 T 13-10-2018 Astex_0084 7789323f05bf99ca8d2504557baea99e 110 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 106 5.5E-38 T 13-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 Astex_0084 7789323f05bf99ca8d2504557baea99e 110 Pfam PF00085 Thioredoxin 6 106 4.6E-34 T 13-10-2018 IPR013766 Thioredoxin domain GO:0045454 Astex_0084 7789323f05bf99ca8d2504557baea99e 110 PIRSF PIRSF000077 2 107 1.1E-42 T 13-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 Astex_0084 7789323f05bf99ca8d2504557baea99e 110 SUPERFAMILY SSF52833 5 107 3.46E-39 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Astex_3662 8d04352d9eb3b4e7a06e55d3647fd0ef 1022 Gene3D G3DSA:1.20.1640.10 15 503 4.8E-228 T 13-10-2018 Astex_3662 8d04352d9eb3b4e7a06e55d3647fd0ef 1022 SUPERFAMILY SSF82714 187 269 1.02E-10 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Astex_3662 8d04352d9eb3b4e7a06e55d3647fd0ef 1022 Gene3D G3DSA:3.30.70.1430 555 654 4.8E-228 T 13-10-2018 Astex_3662 8d04352d9eb3b4e7a06e55d3647fd0ef 1022 Gene3D G3DSA:1.20.1640.10 504 1006 4.8E-228 T 13-10-2018 Astex_3662 8d04352d9eb3b4e7a06e55d3647fd0ef 1022 Pfam PF00873 AcrB/AcrD/AcrF family 7 1007 1.3E-142 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3662 8d04352d9eb3b4e7a06e55d3647fd0ef 1022 SUPERFAMILY SSF82693 43 137 6.02E-14 T 13-10-2018 Astex_3662 8d04352d9eb3b4e7a06e55d3647fd0ef 1022 SUPERFAMILY SSF82714 707 789 1.03E-10 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Astex_3662 8d04352d9eb3b4e7a06e55d3647fd0ef 1022 SUPERFAMILY SSF82693 554 642 9.94E-6 T 13-10-2018 Astex_3662 8d04352d9eb3b4e7a06e55d3647fd0ef 1022 Gene3D G3DSA:3.30.2090.10 706 794 4.8E-228 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Astex_3662 8d04352d9eb3b4e7a06e55d3647fd0ef 1022 SUPERFAMILY SSF82866 298 491 1.31E-35 T 13-10-2018 Astex_3662 8d04352d9eb3b4e7a06e55d3647fd0ef 1022 Gene3D G3DSA:3.30.70.1430 43 802 4.8E-228 T 13-10-2018 Astex_3662 8d04352d9eb3b4e7a06e55d3647fd0ef 1022 Gene3D G3DSA:3.30.70.1320 139 329 4.8E-228 T 13-10-2018 Astex_3662 8d04352d9eb3b4e7a06e55d3647fd0ef 1022 PRINTS PR00702 Acriflavin resistance protein family signature 41 59 2.2E-20 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3662 8d04352d9eb3b4e7a06e55d3647fd0ef 1022 PRINTS PR00702 Acriflavin resistance protein family signature 13 37 2.2E-20 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3662 8d04352d9eb3b4e7a06e55d3647fd0ef 1022 PRINTS PR00702 Acriflavin resistance protein family signature 359 380 2.2E-20 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3662 8d04352d9eb3b4e7a06e55d3647fd0ef 1022 PRINTS PR00702 Acriflavin resistance protein family signature 465 488 2.2E-20 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3662 8d04352d9eb3b4e7a06e55d3647fd0ef 1022 PRINTS PR00702 Acriflavin resistance protein family signature 387 411 2.2E-20 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3662 8d04352d9eb3b4e7a06e55d3647fd0ef 1022 PRINTS PR00702 Acriflavin resistance protein family signature 440 463 2.2E-20 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3662 8d04352d9eb3b4e7a06e55d3647fd0ef 1022 SUPERFAMILY SSF82866 794 1014 4.97E-42 T 13-10-2018 Astex_3662 8d04352d9eb3b4e7a06e55d3647fd0ef 1022 Gene3D G3DSA:3.30.2090.10 182 271 4.8E-228 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Astex_3662 8d04352d9eb3b4e7a06e55d3647fd0ef 1022 Gene3D G3DSA:3.30.70.1440 655 854 4.8E-228 T 13-10-2018 Astex_3662 8d04352d9eb3b4e7a06e55d3647fd0ef 1022 SUPERFAMILY SSF82693 139 326 1.41E-14 T 13-10-2018 Astex_3373 c12f7a7fd3d1cafc4cd120f01df7703c 326 SUPERFAMILY SSF161098 45 316 2.52E-32 T 13-10-2018 IPR035906 MetI-like superfamily Astex_3373 c12f7a7fd3d1cafc4cd120f01df7703c 326 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 317 9.0E-13 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Astex_3373 c12f7a7fd3d1cafc4cd120f01df7703c 326 Gene3D G3DSA:1.10.3720.10 84 325 4.7E-32 T 13-10-2018 IPR035906 MetI-like superfamily Astex_3373 c12f7a7fd3d1cafc4cd120f01df7703c 326 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 30 322 2.3E-85 T 13-10-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 Astex_1172 fb0a5408c9f7c25d914d19b013569f61 559 Gene3D G3DSA:3.30.360.10 390 534 2.6E-59 T 13-10-2018 Astex_1172 fb0a5408c9f7c25d914d19b013569f61 559 Pfam PF00742 Homoserine dehydrogenase 380 550 1.0E-32 T 13-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 Astex_1172 fb0a5408c9f7c25d914d19b013569f61 559 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 263 370 3.3E-10 T 13-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 Astex_1172 fb0a5408c9f7c25d914d19b013569f61 559 Pfam PF00696 Amino acid kinase family 3 220 1.7E-22 T 13-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 Astex_1172 fb0a5408c9f7c25d914d19b013569f61 559 SUPERFAMILY SSF53633 4 234 8.9E-34 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Astex_1172 fb0a5408c9f7c25d914d19b013569f61 559 SUPERFAMILY SSF51735 255 401 1.98E-18 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_1172 fb0a5408c9f7c25d914d19b013569f61 559 Gene3D G3DSA:3.40.50.720 257 551 2.6E-59 T 13-10-2018 Astex_1172 fb0a5408c9f7c25d914d19b013569f61 559 Gene3D G3DSA:3.40.1160.10 1 249 6.3E-43 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Astex_1172 fb0a5408c9f7c25d914d19b013569f61 559 SUPERFAMILY SSF55347 380 538 5.23E-25 T 13-10-2018 Astex_0607 a3e463055037e02efd4d3f5b22b3499d 612 SUPERFAMILY SSF103515 364 607 1.03E-19 T 13-10-2018 IPR036709 Autotransporter beta-domain superfamily Astex_0607 a3e463055037e02efd4d3f5b22b3499d 612 Gene3D G3DSA:3.40.50.1110 16 301 3.3E-63 T 13-10-2018 IPR036514 SGNH hydrolase superfamily Astex_0607 a3e463055037e02efd4d3f5b22b3499d 612 Pfam PF03797 Autotransporter beta-domain 363 581 4.2E-20 T 13-10-2018 IPR005546 Autotransporter beta-domain Astex_0607 a3e463055037e02efd4d3f5b22b3499d 612 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 31 286 4.2E-9 T 13-10-2018 IPR013830 SGNH hydrolase-type esterase domain Astex_0607 a3e463055037e02efd4d3f5b22b3499d 612 SMART SM00869 330 601 3.5E-7 T 13-10-2018 IPR005546 Autotransporter beta-domain Astex_0607 a3e463055037e02efd4d3f5b22b3499d 612 Gene3D G3DSA:2.40.128.130 339 611 2.9E-27 T 13-10-2018 IPR036709 Autotransporter beta-domain superfamily Astex_0607 a3e463055037e02efd4d3f5b22b3499d 612 SUPERFAMILY SSF52266 27 296 4.83E-17 T 13-10-2018 Astex_2444 70e10ad384765efe6cb1dc04cfd40321 695 Gene3D G3DSA:3.40.50.1820 393 669 1.5E-32 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_2444 70e10ad384765efe6cb1dc04cfd40321 695 SUPERFAMILY SSF82171 61 395 9.42E-14 T 13-10-2018 Astex_2444 70e10ad384765efe6cb1dc04cfd40321 695 SUPERFAMILY SSF53474 401 660 1.05E-26 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_2444 70e10ad384765efe6cb1dc04cfd40321 695 Pfam PF00326 Prolyl oligopeptidase family 507 661 9.9E-10 T 13-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 Astex_2444 70e10ad384765efe6cb1dc04cfd40321 695 Gene3D G3DSA:2.120.10.30 28 211 1.6E-10 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like Astex_2843 bb9fb9f0da96ba55ac75d37e1487eaa5 255 SUPERFAMILY SSF52313 8 227 3.14E-87 T 13-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily Astex_2843 bb9fb9f0da96ba55ac75d37e1487eaa5 255 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 158 182 - T 13-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 Astex_2843 bb9fb9f0da96ba55ac75d37e1487eaa5 255 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 4 229 38.973 T 13-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_2843 bb9fb9f0da96ba55ac75d37e1487eaa5 255 PRINTS PR00395 Ribosomal protein S2 signature 8 26 3.8E-36 T 13-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_2843 bb9fb9f0da96ba55ac75d37e1487eaa5 255 PRINTS PR00395 Ribosomal protein S2 signature 89 106 3.8E-36 T 13-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_2843 bb9fb9f0da96ba55ac75d37e1487eaa5 255 PRINTS PR00395 Ribosomal protein S2 signature 39 48 3.8E-36 T 13-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_2843 bb9fb9f0da96ba55ac75d37e1487eaa5 255 PRINTS PR00395 Ribosomal protein S2 signature 175 186 3.8E-36 T 13-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_2843 bb9fb9f0da96ba55ac75d37e1487eaa5 255 PRINTS PR00395 Ribosomal protein S2 signature 158 175 3.8E-36 T 13-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_2843 bb9fb9f0da96ba55ac75d37e1487eaa5 255 PRINTS PR00395 Ribosomal protein S2 signature 196 210 3.8E-36 T 13-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_2843 bb9fb9f0da96ba55ac75d37e1487eaa5 255 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 6 225 2.2E-91 T 13-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_2843 bb9fb9f0da96ba55ac75d37e1487eaa5 255 Pfam PF00318 Ribosomal protein S2 11 224 1.1E-88 T 13-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_2843 bb9fb9f0da96ba55ac75d37e1487eaa5 255 Gene3D G3DSA:1.10.287.610 102 151 2.5E-16 T 13-10-2018 Astex_2843 bb9fb9f0da96ba55ac75d37e1487eaa5 255 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 8 19 - T 13-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 Astex_3740 85ab42801c38b6f17bc9ca2edd840c49 157 Gene3D G3DSA:3.90.930.1 13 75 1.1E-5 T 13-10-2018 Astex_3740 85ab42801c38b6f17bc9ca2edd840c49 157 Pfam PF05593 RHS Repeat 21 43 5.1E-5 T 13-10-2018 IPR031325 RHS repeat Astex_3740 85ab42801c38b6f17bc9ca2edd840c49 157 Pfam PF05593 RHS Repeat 28 58 2.3E-8 T 13-10-2018 IPR031325 RHS repeat Astex_3740 85ab42801c38b6f17bc9ca2edd840c49 157 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 22 47 3.3E-5 T 13-10-2018 IPR006530 YD repeat Astex_3740 85ab42801c38b6f17bc9ca2edd840c49 157 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 28 57 3.0E-7 T 13-10-2018 IPR006530 YD repeat Astex_3493 3b010b245202bf687dae3a926b853eaa 143 Pfam PF01575 MaoC like domain 19 119 9.4E-19 T 13-10-2018 IPR002539 MaoC-like dehydratase domain Astex_3493 3b010b245202bf687dae3a926b853eaa 143 Gene3D G3DSA:3.10.129.10 4 142 4.3E-39 T 13-10-2018 Astex_3493 3b010b245202bf687dae3a926b853eaa 143 SUPERFAMILY SSF54637 6 142 1.09E-36 T 13-10-2018 IPR029069 HotDog domain superfamily Astex_2300 78f6944fe9e2a33f74d0066ff8c2bc7c 125 SMART SM00530 14 69 8.8E-12 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Astex_2300 78f6944fe9e2a33f74d0066ff8c2bc7c 125 Pfam PF01381 Helix-turn-helix 15 69 1.2E-10 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Astex_2300 78f6944fe9e2a33f74d0066ff8c2bc7c 125 SUPERFAMILY SSF47413 5 77 2.31E-24 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Astex_2300 78f6944fe9e2a33f74d0066ff8c2bc7c 125 Gene3D G3DSA:1.10.260.40 8 96 8.5E-17 T 13-10-2018 Astex_1897 45c0f61acf5c0f33112efdab26db19ad 129 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 4 127 5.3E-41 T 13-10-2018 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-6798695|Reactome: R-HSA-73614 Astex_1897 45c0f61acf5c0f33112efdab26db19ad 129 SUPERFAMILY SSF53927 4 126 2.01E-39 T 13-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 Astex_1897 45c0f61acf5c0f33112efdab26db19ad 129 Gene3D G3DSA:3.40.140.10 1 129 1.7E-42 T 13-10-2018 Astex_1897 45c0f61acf5c0f33112efdab26db19ad 129 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 5 96 5.8E-11 T 13-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain Astex_1897 45c0f61acf5c0f33112efdab26db19ad 129 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 52 92 - T 13-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 Astex_2644 74a470f400a96739611910a7d510f84c 348 Gene3D G3DSA:2.40.10.240 62 165 1.8E-104 T 13-10-2018 Astex_2644 74a470f400a96739611910a7d510f84c 348 SUPERFAMILY SSF111337 1 343 4.19E-121 T 13-10-2018 IPR036100 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA superfamily GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 Astex_2644 74a470f400a96739611910a7d510f84c 348 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1 343 3.9E-108 T 13-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 Astex_2644 74a470f400a96739611910a7d510f84c 348 Pfam PF02547 Queuosine biosynthesis protein 3 343 1.7E-121 T 13-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 Astex_2644 74a470f400a96739611910a7d510f84c 348 Gene3D G3DSA:3.40.1780.10 15 342 1.8E-104 T 13-10-2018 Astex_2644 74a470f400a96739611910a7d510f84c 348 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 344 42.735 T 13-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 Astex_3573 6961d67f0ce4ce2ed54a42b798939760 267 TIGRFAM TIGR04378 myo_inos_iolB: 5-deoxy-glucuronate isomerase 19 264 1.9E-100 T 13-10-2018 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 Astex_3573 6961d67f0ce4ce2ed54a42b798939760 267 SUPERFAMILY SSF51182 15 253 7.68E-69 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily Astex_3573 6961d67f0ce4ce2ed54a42b798939760 267 PIRSF PIRSF036628 1 267 1.3E-105 T 13-10-2018 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 Astex_3573 6961d67f0ce4ce2ed54a42b798939760 267 Pfam PF04962 KduI/IolB family 12 264 4.8E-104 T 13-10-2018 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 Astex_3573 6961d67f0ce4ce2ed54a42b798939760 267 Gene3D G3DSA:2.60.120.10 20 127 4.9E-91 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Astex_3573 6961d67f0ce4ce2ed54a42b798939760 267 Gene3D G3DSA:2.60.120.10 128 263 4.9E-91 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Astex_0283 1467c6050f91be29d5f15589fb1fc9fa 355 Gene3D G3DSA:3.40.50.2000 1 174 4.6E-18 T 13-10-2018 Astex_0283 1467c6050f91be29d5f15589fb1fc9fa 355 Pfam PF13439 Glycosyltransferase Family 4 15 165 1.7E-13 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 Astex_0283 1467c6050f91be29d5f15589fb1fc9fa 355 SUPERFAMILY SSF53756 2 327 7.85E-57 T 13-10-2018 Astex_0283 1467c6050f91be29d5f15589fb1fc9fa 355 Gene3D G3DSA:3.40.50.2000 175 320 2.5E-24 T 13-10-2018 Astex_0283 1467c6050f91be29d5f15589fb1fc9fa 355 Pfam PF13692 Glycosyl transferases group 1 181 301 2.4E-17 T 13-10-2018 Astex_0954 db007ee3028c86ccfad70733a380df62 79 SUPERFAMILY SSF50249 3 75 3.34E-26 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Astex_0954 db007ee3028c86ccfad70733a380df62 79 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 3 73 2.9E-29 T 13-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_0954 db007ee3028c86ccfad70733a380df62 79 Pfam PF00366 Ribosomal protein S17 8 74 2.4E-24 T 13-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_0954 db007ee3028c86ccfad70733a380df62 79 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 1 74 3.0E-30 T 13-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_0954 db007ee3028c86ccfad70733a380df62 79 PRINTS PR00973 Ribosomal protein S17 family signature 54 64 2.0E-5 T 13-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_0954 db007ee3028c86ccfad70733a380df62 79 PRINTS PR00973 Ribosomal protein S17 family signature 22 45 2.0E-5 T 13-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_0954 db007ee3028c86ccfad70733a380df62 79 PRINTS PR00973 Ribosomal protein S17 family signature 64 71 2.0E-5 T 13-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_0954 db007ee3028c86ccfad70733a380df62 79 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 3 76 19.65 T 13-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_0954 db007ee3028c86ccfad70733a380df62 79 Gene3D G3DSA:2.40.50.140 1 78 6.2E-27 T 13-10-2018 Astex_0255 6251ce4405734c00a195fe702c1871fb 304 Gene3D G3DSA:1.10.443.10 118 297 5.0E-50 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 Astex_0255 6251ce4405734c00a195fe702c1871fb 304 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 9 93 3.5E-15 T 13-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 Astex_0255 6251ce4405734c00a195fe702c1871fb 304 Pfam PF00589 Phage integrase family 120 290 8.1E-38 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 Astex_0255 6251ce4405734c00a195fe702c1871fb 304 Gene3D G3DSA:1.10.150.130 8 105 2.1E-15 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal Astex_0255 6251ce4405734c00a195fe702c1871fb 304 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 5 304 49.295 T 13-10-2018 IPR023009 Tyrosine recombinase XerC/XerD Astex_0255 6251ce4405734c00a195fe702c1871fb 304 SUPERFAMILY SSF56349 114 302 4.41E-48 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 Astex_0255 6251ce4405734c00a195fe702c1871fb 304 SUPERFAMILY SSF47823 11 108 5.49E-5 T 13-10-2018 Astex_1616 e878d3db681afb73108e286528bea040 173 SUPERFAMILY SSF55200 87 173 1.16E-33 T 13-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 Astex_1616 e878d3db681afb73108e286528bea040 173 ProSitePatterns PS00938 Initiation factor 3 signature. 63 76 - T 13-10-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 Astex_1616 e878d3db681afb73108e286528bea040 173 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 88 173 4.4E-39 T 13-10-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 Astex_1616 e878d3db681afb73108e286528bea040 173 SUPERFAMILY SSF54364 9 83 1.96E-28 T 13-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 Astex_1616 e878d3db681afb73108e286528bea040 173 Gene3D G3DSA:3.10.20.80 7 80 1.4E-31 T 13-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 Astex_1616 e878d3db681afb73108e286528bea040 173 Gene3D G3DSA:3.30.110.10 81 173 2.2E-38 T 13-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 Astex_1616 e878d3db681afb73108e286528bea040 173 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 5 173 28.876 T 13-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 Astex_1616 e878d3db681afb73108e286528bea040 173 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 12 81 1.7E-29 T 13-10-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 Astex_1616 e878d3db681afb73108e286528bea040 173 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 12 173 8.4E-68 T 13-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 Astex_0459 c58f67d5e64c84dd285f39b39ddcb945 72 Gene3D G3DSA:2.60.260.40 4 55 1.6E-22 T 13-10-2018 Astex_0459 c58f67d5e64c84dd285f39b39ddcb945 72 Pfam PF10276 Zinc-finger domain 17 52 8.4E-18 T 13-10-2018 IPR019401 Zinc finger, CHCC-type Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_1846 d719fa3a756dd579e9000260b0b85a27 327 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 2 307 1.7E-89 T 13-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 Astex_1846 d719fa3a756dd579e9000260b0b85a27 327 SUPERFAMILY SSF53335 5 307 2.72E-43 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Astex_1846 d719fa3a756dd579e9000260b0b85a27 327 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 6 308 35.208 T 13-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 Astex_1846 d719fa3a756dd579e9000260b0b85a27 327 Gene3D G3DSA:1.10.150.170 110 212 3.8E-98 T 13-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 Astex_1846 d719fa3a756dd579e9000260b0b85a27 327 Gene3D G3DSA:3.40.50.150 6 305 3.8E-98 T 13-10-2018 Astex_1846 d719fa3a756dd579e9000260b0b85a27 327 PIRSF PIRSF004486 1 309 1.6E-97 T 13-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 Astex_1846 d719fa3a756dd579e9000260b0b85a27 327 SUPERFAMILY SSF81799 112 211 3.14E-34 T 13-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 Astex_1846 d719fa3a756dd579e9000260b0b85a27 327 Pfam PF01795 MraW methylase family 4 307 7.1E-94 T 13-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 Astex_0007 094ef1d15a15e056993fe3e25131ed77 411 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 125 136 - T 13-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Astex_0007 094ef1d15a15e056993fe3e25131ed77 411 TIGRFAM TIGR00032 argG: argininosuccinate synthase 11 405 6.0E-141 T 13-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Astex_0007 094ef1d15a15e056993fe3e25131ed77 411 Gene3D G3DSA:3.90.1260.10 185 410 3.9E-98 T 13-10-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Astex_0007 094ef1d15a15e056993fe3e25131ed77 411 SUPERFAMILY SSF52402 10 175 2.21E-46 T 13-10-2018 Astex_0007 094ef1d15a15e056993fe3e25131ed77 411 Pfam PF00764 Arginosuccinate synthase 13 404 4.1E-153 T 13-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Astex_0007 094ef1d15a15e056993fe3e25131ed77 411 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 15 23 - T 13-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Astex_0007 094ef1d15a15e056993fe3e25131ed77 411 SUPERFAMILY SSF69864 183 407 1.44E-91 T 13-10-2018 Astex_0007 094ef1d15a15e056993fe3e25131ed77 411 Hamap MF_00005 Argininosuccinate synthase [argG]. 9 409 52.282 T 13-10-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Astex_0007 094ef1d15a15e056993fe3e25131ed77 411 Gene3D G3DSA:3.40.50.620 10 181 1.9E-66 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Astex_2611 d83513033d4995b466cdf09b5868e323 457 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 61 361 1.1E-96 T 13-10-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 Astex_2611 d83513033d4995b466cdf09b5868e323 457 Gene3D G3DSA:3.30.590.20 2 457 3.8E-176 T 13-10-2018 Astex_2611 d83513033d4995b466cdf09b5868e323 457 TIGRFAM TIGR01436 glu_cys_lig_pln: glutamate--cysteine ligase 10 457 2.5E-196 T 13-10-2018 IPR011556 Glutamate--cysteine ligase, plant-type GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 Astex_2611 d83513033d4995b466cdf09b5868e323 457 SUPERFAMILY SSF55931 24 442 3.53E-67 T 13-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Astex_2611 d83513033d4995b466cdf09b5868e323 457 PIRSF PIRSF017901 3 457 1.1E-179 T 13-10-2018 IPR035434 Glutamate--cysteine ligase, bacteria and plant GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 Astex_0124 7b52392a7e25d5bf3f5353188033b54a 266 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 29 38 - T 13-10-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Astex_0124 7b52392a7e25d5bf3f5353188033b54a 266 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 4 265 6.4E-60 T 13-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 Astex_0124 7b52392a7e25d5bf3f5353188033b54a 266 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 3 264 5.0E-63 T 13-10-2018 Astex_0124 7b52392a7e25d5bf3f5353188033b54a 266 Gene3D G3DSA:3.60.10.10 3 266 3.0E-62 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily Astex_0124 7b52392a7e25d5bf3f5353188033b54a 266 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 6 257 5.9E-17 T 13-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase Astex_0124 7b52392a7e25d5bf3f5353188033b54a 266 SUPERFAMILY SSF56219 3 266 1.44E-68 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily Astex_2899 1ba7dd0489a8cb46c229403cf0ef29ae 507 PRINTS PR00095 Anthranilate synthase component I signature 350 363 5.7E-18 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 Astex_2899 1ba7dd0489a8cb46c229403cf0ef29ae 507 PRINTS PR00095 Anthranilate synthase component I signature 446 460 5.7E-18 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 Astex_2899 1ba7dd0489a8cb46c229403cf0ef29ae 507 PRINTS PR00095 Anthranilate synthase component I signature 431 445 5.7E-18 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 Astex_2899 1ba7dd0489a8cb46c229403cf0ef29ae 507 PRINTS PR00095 Anthranilate synthase component I signature 336 349 5.7E-18 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 Astex_2899 1ba7dd0489a8cb46c229403cf0ef29ae 507 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 35 497 1.1E-167 T 13-10-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 Astex_2899 1ba7dd0489a8cb46c229403cf0ef29ae 507 SUPERFAMILY SSF56322 25 497 1.16E-149 T 13-10-2018 IPR005801 ADC synthase GO:0009058 Astex_2899 1ba7dd0489a8cb46c229403cf0ef29ae 507 Gene3D G3DSA:3.60.120.10 4 505 1.4E-171 T 13-10-2018 IPR005801 ADC synthase GO:0009058 Astex_2899 1ba7dd0489a8cb46c229403cf0ef29ae 507 Pfam PF00425 chorismate binding enzyme 235 489 4.0E-97 T 13-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal Astex_2899 1ba7dd0489a8cb46c229403cf0ef29ae 507 Pfam PF04715 Anthranilate synthase component I, N terminal region 35 180 8.0E-26 T 13-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 Astex_0854 cf0998413f6d88caca71e6bb2e1b0d19 243 SUPERFAMILY SSF52540 7 231 1.45E-64 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0854 cf0998413f6d88caca71e6bb2e1b0d19 243 Pfam PF00005 ABC transporter 26 175 1.8E-32 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_0854 cf0998413f6d88caca71e6bb2e1b0d19 243 SMART SM00382 35 223 5.9E-18 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_0854 cf0998413f6d88caca71e6bb2e1b0d19 243 Gene3D G3DSA:3.40.50.300 5 236 6.0E-67 T 13-10-2018 Astex_0854 cf0998413f6d88caca71e6bb2e1b0d19 243 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Astex_1361 fd24f49b0d658d09ea752e21cb96fe51 815 SMART SM00490 268 349 5.2E-16 T 13-10-2018 IPR001650 Helicase, C-terminal Astex_1361 fd24f49b0d658d09ea752e21cb96fe51 815 TIGRFAM TIGR04121 DEXH_lig_assoc: DEXH box helicase, DNA ligase-associated 6 797 0.0 T 13-10-2018 IPR026362 DEXH box helicase, DNA ligase-associated Astex_1361 fd24f49b0d658d09ea752e21cb96fe51 815 SUPERFAMILY SSF52540 63 346 1.13E-44 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1361 fd24f49b0d658d09ea752e21cb96fe51 815 PIRSF PIRSF037307 1 808 1.2E-166 T 13-10-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 Astex_1361 fd24f49b0d658d09ea752e21cb96fe51 815 SMART SM00487 14 212 3.6E-24 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Astex_1361 fd24f49b0d658d09ea752e21cb96fe51 815 Pfam PF00270 DEAD/DEAH box helicase 20 187 2.0E-22 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Astex_1361 fd24f49b0d658d09ea752e21cb96fe51 815 Pfam PF00271 Helicase conserved C-terminal domain 242 344 6.7E-18 T 13-10-2018 IPR001650 Helicase, C-terminal Astex_1361 fd24f49b0d658d09ea752e21cb96fe51 815 Gene3D G3DSA:3.40.50.300 9 205 5.5E-43 T 13-10-2018 Astex_1361 fd24f49b0d658d09ea752e21cb96fe51 815 Gene3D G3DSA:3.40.50.300 236 395 9.2E-26 T 13-10-2018 Astex_1361 fd24f49b0d658d09ea752e21cb96fe51 815 Pfam PF08494 DEAD/H associated 589 772 4.9E-45 T 13-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 Astex_2717 f2b364fdec89ecf73d70f93055c2d35d 419 Gene3D G3DSA:3.30.50.30 2 51 3.6E-24 T 13-10-2018 IPR038366 Zinc finger, ClpX C4-type superfamily Astex_2717 f2b364fdec89ecf73d70f93055c2d35d 419 SMART SM00994 12 51 1.7E-24 T 13-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 Astex_2717 f2b364fdec89ecf73d70f93055c2d35d 419 Pfam PF07724 AAA domain (Cdc48 subfamily) 111 307 1.2E-49 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Astex_2717 f2b364fdec89ecf73d70f93055c2d35d 419 Pfam PF06689 ClpX C4-type zinc finger 13 50 5.9E-20 T 13-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 Astex_2717 f2b364fdec89ecf73d70f93055c2d35d 419 SUPERFAMILY SSF57716 13 48 1.18E-11 T 13-10-2018 Astex_2717 f2b364fdec89ecf73d70f93055c2d35d 419 Gene3D G3DSA:3.40.50.300 56 312 5.9E-108 T 13-10-2018 Astex_2717 f2b364fdec89ecf73d70f93055c2d35d 419 SMART SM01086 314 409 1.3E-32 T 13-10-2018 IPR019489 Clp ATPase, C-terminal Astex_2717 f2b364fdec89ecf73d70f93055c2d35d 419 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 314 388 1.0E-15 T 13-10-2018 IPR019489 Clp ATPase, C-terminal Astex_2717 f2b364fdec89ecf73d70f93055c2d35d 419 Gene3D G3DSA:1.10.8.60 313 418 1.4E-39 T 13-10-2018 Astex_2717 f2b364fdec89ecf73d70f93055c2d35d 419 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 10 409 4.3E-203 T 13-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 Astex_2717 f2b364fdec89ecf73d70f93055c2d35d 419 SUPERFAMILY SSF52540 61 396 3.45E-74 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2717 f2b364fdec89ecf73d70f93055c2d35d 419 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 412 53.681 T 13-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 Astex_2717 f2b364fdec89ecf73d70f93055c2d35d 419 SMART SM00382 110 262 2.8E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_0944 d2d1da56c4e5917c44f35873330ec562 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 13-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0944 d2d1da56c4e5917c44f35873330ec562 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 27.393 T 13-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0944 d2d1da56c4e5917c44f35873330ec562 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 3.0E-37 T 13-10-2018 IPR027486 Ribosomal protein S10 domain Astex_0944 d2d1da56c4e5917c44f35873330ec562 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 6.5E-18 T 13-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0944 d2d1da56c4e5917c44f35873330ec562 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 6.5E-18 T 13-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0944 d2d1da56c4e5917c44f35873330ec562 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 6.5E-18 T 13-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0944 d2d1da56c4e5917c44f35873330ec562 102 SMART SM01403 7 101 2.2E-58 T 13-10-2018 IPR027486 Ribosomal protein S10 domain Astex_0944 d2d1da56c4e5917c44f35873330ec562 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 4.3E-46 T 13-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0944 d2d1da56c4e5917c44f35873330ec562 102 Gene3D G3DSA:3.30.70.600 1 102 3.4E-40 T 13-10-2018 IPR036838 Ribosomal protein S10 domain superfamily Astex_0944 d2d1da56c4e5917c44f35873330ec562 102 SUPERFAMILY SSF54999 6 102 6.54E-40 T 13-10-2018 IPR036838 Ribosomal protein S10 domain superfamily Astex_2777 0cc5d181e120b60980a663bac744b200 468 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 258 273 - T 13-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 Astex_2777 0cc5d181e120b60980a663bac744b200 468 ProSitePatterns PS00180 Glutamine synthetase signature 1. 50 68 - T 13-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 Astex_2777 0cc5d181e120b60980a663bac744b200 468 SUPERFAMILY SSF55931 103 466 4.02E-138 T 13-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Astex_2777 0cc5d181e120b60980a663bac744b200 468 Gene3D G3DSA:3.30.590.10 105 454 4.8E-143 T 13-10-2018 Astex_2777 0cc5d181e120b60980a663bac744b200 468 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 14 95 2.3E-30 T 13-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 Astex_2777 0cc5d181e120b60980a663bac744b200 468 Pfam PF00120 Glutamine synthetase, catalytic domain 103 465 4.6E-139 T 13-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Astex_2777 0cc5d181e120b60980a663bac744b200 468 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 5 467 1.1E-196 T 13-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Astex_2777 0cc5d181e120b60980a663bac744b200 468 SUPERFAMILY SSF54368 2 101 1.31E-36 T 13-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Astex_2777 0cc5d181e120b60980a663bac744b200 468 Gene3D G3DSA:3.10.20.70 2 104 4.9E-38 T 13-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Astex_2777 0cc5d181e120b60980a663bac744b200 468 SMART SM01230 102 378 3.6E-145 T 13-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Astex_1996 8bc6ad6f22f812d1e07cef40777a2987 527 Pfam PF00512 His Kinase A (phospho-acceptor) domain 156 220 5.5E-17 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_1996 8bc6ad6f22f812d1e07cef40777a2987 527 SUPERFAMILY SSF55874 210 379 1.96E-43 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_1996 8bc6ad6f22f812d1e07cef40777a2987 527 Pfam PF00072 Response regulator receiver domain 11 116 1.3E-22 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1996 8bc6ad6f22f812d1e07cef40777a2987 527 Pfam PF00072 Response regulator receiver domain 406 521 3.2E-23 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1996 8bc6ad6f22f812d1e07cef40777a2987 527 Gene3D G3DSA:3.40.50.12740 403 527 3.0E-39 T 13-10-2018 Astex_1996 8bc6ad6f22f812d1e07cef40777a2987 527 Gene3D G3DSA:3.30.565.10 222 384 3.7E-46 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_1996 8bc6ad6f22f812d1e07cef40777a2987 527 SMART SM00448 404 521 3.4E-35 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1996 8bc6ad6f22f812d1e07cef40777a2987 527 SMART SM00448 9 122 6.6E-28 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1996 8bc6ad6f22f812d1e07cef40777a2987 527 PRINTS PR00344 Bacterial sensor protein C-terminal signature 366 379 4.3E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1996 8bc6ad6f22f812d1e07cef40777a2987 527 PRINTS PR00344 Bacterial sensor protein C-terminal signature 325 335 4.3E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1996 8bc6ad6f22f812d1e07cef40777a2987 527 PRINTS PR00344 Bacterial sensor protein C-terminal signature 342 360 4.3E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1996 8bc6ad6f22f812d1e07cef40777a2987 527 PRINTS PR00344 Bacterial sensor protein C-terminal signature 307 321 4.3E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1996 8bc6ad6f22f812d1e07cef40777a2987 527 SUPERFAMILY SSF52172 10 173 3.84E-31 T 13-10-2018 IPR011006 CheY-like superfamily Astex_1996 8bc6ad6f22f812d1e07cef40777a2987 527 Gene3D G3DSA:3.40.50.2300 7 126 4.5E-28 T 13-10-2018 Astex_1996 8bc6ad6f22f812d1e07cef40777a2987 527 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 267 380 2.8E-29 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_1996 8bc6ad6f22f812d1e07cef40777a2987 527 SMART SM00388 156 221 4.5E-21 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_1996 8bc6ad6f22f812d1e07cef40777a2987 527 SUPERFAMILY SSF52172 402 523 3.42E-34 T 13-10-2018 IPR011006 CheY-like superfamily Astex_1996 8bc6ad6f22f812d1e07cef40777a2987 527 SMART SM00387 267 382 1.7E-37 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_1996 8bc6ad6f22f812d1e07cef40777a2987 527 Gene3D G3DSA:1.10.287.130 127 220 1.9E-28 T 13-10-2018 Astex_0966 9f68a918392574b191b017b28e20d6d2 190 PRINTS PR00094 Adenylate kinase signature 32 46 5.2E-32 T 13-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 Astex_0966 9f68a918392574b191b017b28e20d6d2 190 PRINTS PR00094 Adenylate kinase signature 81 97 5.2E-32 T 13-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 Astex_0966 9f68a918392574b191b017b28e20d6d2 190 PRINTS PR00094 Adenylate kinase signature 4 17 5.2E-32 T 13-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 Astex_0966 9f68a918392574b191b017b28e20d6d2 190 PRINTS PR00094 Adenylate kinase signature 150 164 5.2E-32 T 13-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 Astex_0966 9f68a918392574b191b017b28e20d6d2 190 PRINTS PR00094 Adenylate kinase signature 133 148 5.2E-32 T 13-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 Astex_0966 9f68a918392574b191b017b28e20d6d2 190 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 13-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 Astex_0966 9f68a918392574b191b017b28e20d6d2 190 SUPERFAMILY SSF52540 1 186 2.0E-38 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0966 9f68a918392574b191b017b28e20d6d2 190 Pfam PF00406 Adenylate kinase 5 163 2.5E-51 T 13-10-2018 Astex_0966 9f68a918392574b191b017b28e20d6d2 190 Hamap MF_00235 Adenylate kinase [adk]. 1 186 43.575 T 13-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 Astex_0966 9f68a918392574b191b017b28e20d6d2 190 Gene3D G3DSA:3.40.50.300 1 190 1.2E-60 T 13-10-2018 Astex_0503 022be8aba920d955caaa15af86baadcb 442 Pfam PF14698 Argininosuccinate lyase C-terminal 348 415 5.9E-25 T 13-10-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Astex_0503 022be8aba920d955caaa15af86baadcb 442 Gene3D G3DSA:1.20.200.10 104 434 7.5E-188 T 13-10-2018 Astex_0503 022be8aba920d955caaa15af86baadcb 442 Gene3D G3DSA:1.10.40.30 345 418 7.5E-188 T 13-10-2018 Astex_0503 022be8aba920d955caaa15af86baadcb 442 Gene3D G3DSA:1.10.275.10 10 214 7.5E-188 T 13-10-2018 IPR024083 Fumarase/histidase, N-terminal Astex_0503 022be8aba920d955caaa15af86baadcb 442 Hamap MF_00006 Argininosuccinate lyase [argH]. 2 439 40.362 T 13-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Astex_0503 022be8aba920d955caaa15af86baadcb 442 Pfam PF00206 Lyase 1 285 9.3E-77 T 13-10-2018 IPR022761 Fumarate lyase, N-terminal Astex_0503 022be8aba920d955caaa15af86baadcb 442 PRINTS PR00145 Argininosuccinate lyase family signature 86 108 2.0E-62 T 13-10-2018 Astex_0503 022be8aba920d955caaa15af86baadcb 442 PRINTS PR00145 Argininosuccinate lyase family signature 178 194 2.0E-62 T 13-10-2018 Astex_0503 022be8aba920d955caaa15af86baadcb 442 PRINTS PR00145 Argininosuccinate lyase family signature 295 314 2.0E-62 T 13-10-2018 Astex_0503 022be8aba920d955caaa15af86baadcb 442 PRINTS PR00145 Argininosuccinate lyase family signature 260 276 2.0E-62 T 13-10-2018 Astex_0503 022be8aba920d955caaa15af86baadcb 442 PRINTS PR00145 Argininosuccinate lyase family signature 216 240 2.0E-62 T 13-10-2018 Astex_0503 022be8aba920d955caaa15af86baadcb 442 PRINTS PR00145 Argininosuccinate lyase family signature 127 147 2.0E-62 T 13-10-2018 Astex_0503 022be8aba920d955caaa15af86baadcb 442 PRINTS PR00149 Fumarate lyase superfamily signature 216 243 2.1E-28 T 13-10-2018 IPR000362 Fumarate lyase family Astex_0503 022be8aba920d955caaa15af86baadcb 442 PRINTS PR00149 Fumarate lyase superfamily signature 260 276 2.1E-28 T 13-10-2018 IPR000362 Fumarate lyase family Astex_0503 022be8aba920d955caaa15af86baadcb 442 PRINTS PR00149 Fumarate lyase superfamily signature 87 105 2.1E-28 T 13-10-2018 IPR000362 Fumarate lyase family Astex_0503 022be8aba920d955caaa15af86baadcb 442 PRINTS PR00149 Fumarate lyase superfamily signature 132 150 2.1E-28 T 13-10-2018 IPR000362 Fumarate lyase family Astex_0503 022be8aba920d955caaa15af86baadcb 442 ProSitePatterns PS00163 Fumarate lyases signature. 260 269 - T 13-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 Astex_0503 022be8aba920d955caaa15af86baadcb 442 TIGRFAM TIGR00838 argH: argininosuccinate lyase 2 440 2.9E-175 T 13-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 Astex_0503 022be8aba920d955caaa15af86baadcb 442 SUPERFAMILY SSF48557 3 441 1.02E-146 T 13-10-2018 IPR008948 L-Aspartase-like GO:0003824 Astex_3289 7525ec3e2bb1a769ff311640a6e5db9c 209 SUPERFAMILY SSF47616 82 208 6.82E-27 T 13-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily Astex_3289 7525ec3e2bb1a769ff311640a6e5db9c 209 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 81 3.7E-18 T 13-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 Astex_3289 7525ec3e2bb1a769ff311640a6e5db9c 209 SUPERFAMILY SSF52833 1 90 6.28E-27 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Astex_3289 7525ec3e2bb1a769ff311640a6e5db9c 209 Pfam PF14497 Glutathione S-transferase, C-terminal domain 124 196 4.9E-5 T 13-10-2018 IPR004046 Glutathione S-transferase, C-terminal Astex_3289 7525ec3e2bb1a769ff311640a6e5db9c 209 TIGRFAM TIGR01262 maiA: maleylacetoacetate isomerase 2 208 9.1E-80 T 13-10-2018 IPR005955 Glutathione S-transferases, class Zeta GO:0003824|GO:0005737|GO:0009072 Reactome: R-HSA-156590|Reactome: R-HSA-204174|Reactome: R-HSA-71182 Astex_3289 7525ec3e2bb1a769ff311640a6e5db9c 209 Gene3D G3DSA:3.40.30.10 1 87 3.3E-28 T 13-10-2018 Astex_3289 7525ec3e2bb1a769ff311640a6e5db9c 209 Gene3D G3DSA:1.20.1050.10 88 209 5.5E-44 T 13-10-2018 Astex_0229 b52b79206a7a02c2c18a0bc79d232b4a 162 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 21 157 6.8E-32 T 13-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like Astex_0229 b52b79206a7a02c2c18a0bc79d232b4a 162 SUPERFAMILY SSF55961 8 160 7.13E-48 T 13-10-2018 Astex_0229 b52b79206a7a02c2c18a0bc79d232b4a 162 Gene3D G3DSA:3.30.530.20 5 161 3.7E-45 T 13-10-2018 IPR023393 START-like domain superfamily Astex_3617 634c30565e5fbec9c568ba9c1e5b0de9 765 Gene3D G3DSA:3.30.379.10 19 122 3.5E-10 T 13-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 Astex_3617 634c30565e5fbec9c568ba9c1e5b0de9 765 Gene3D G3DSA:1.20.120.670 494 763 1.4E-51 T 13-10-2018 Astex_3617 634c30565e5fbec9c568ba9c1e5b0de9 765 Pfam PF12971 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain 36 114 7.7E-16 T 13-10-2018 IPR024240 Alpha-N-acetylglucosaminidase, N-terminal KEGG: 00531+3.2.1.50|Reactome: R-HSA-2024096|Reactome: R-HSA-2206282 Astex_3617 634c30565e5fbec9c568ba9c1e5b0de9 765 Pfam PF12972 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain 498 758 1.4E-55 T 13-10-2018 IPR024732 Alpha-N-acetylglucosaminidase, C-terminal KEGG: 00531+3.2.1.50|Reactome: R-HSA-2024096|Reactome: R-HSA-2206282 Astex_3617 634c30565e5fbec9c568ba9c1e5b0de9 765 Pfam PF05089 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain 128 489 1.1E-140 T 13-10-2018 IPR024733 Alpha-N-acetylglucosaminidase, tim-barrel domain KEGG: 00531+3.2.1.50|Reactome: R-HSA-2024096|Reactome: R-HSA-2206282 Astex_3617 634c30565e5fbec9c568ba9c1e5b0de9 765 Gene3D G3DSA:3.20.20.80 124 342 2.5E-83 T 13-10-2018 Astex_1382 3b05d8e5d18ed5e7f664f34644dfda5f 1039 Pfam PF10518 TAT (twin-arginine translocation) pathway signal sequence 4 26 3.1E-5 T 13-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal Astex_1382 3b05d8e5d18ed5e7f664f34644dfda5f 1039 SUPERFAMILY SSF49303 239 347 4.56E-6 T 13-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily Astex_1382 3b05d8e5d18ed5e7f664f34644dfda5f 1039 SUPERFAMILY SSF51445 344 627 3.56E-24 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_1382 3b05d8e5d18ed5e7f664f34644dfda5f 1039 SUPERFAMILY SSF49785 82 197 3.83E-20 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_1382 3b05d8e5d18ed5e7f664f34644dfda5f 1039 Gene3D G3DSA:3.20.20.80 358 690 3.2E-22 T 13-10-2018 Astex_1382 3b05d8e5d18ed5e7f664f34644dfda5f 1039 Gene3D G3DSA:2.60.120.260 70 232 8.5E-20 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_1382 3b05d8e5d18ed5e7f664f34644dfda5f 1039 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 76 209 5.6E-8 T 13-10-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_1382 3b05d8e5d18ed5e7f664f34644dfda5f 1039 Pfam PF00703 Glycosyl hydrolases family 2 239 347 4.6E-5 T 13-10-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_2672 1fd6b5c28af3099b9203c8ace80eb1d7 300 Pfam PF03524 Conjugal transfer protein 69 286 1.0E-59 T 13-10-2018 IPR010258 Conjugal transfer, TrbG/VirB9/CagX Astex_2672 1fd6b5c28af3099b9203c8ace80eb1d7 300 TIGRFAM TIGR02775 TrbG_Ti: P-type conjugative transfer protein TrbG 70 275 6.5E-67 T 13-10-2018 IPR014142 P-type conjugative transfer protein TrbG Astex_2672 1fd6b5c28af3099b9203c8ace80eb1d7 300 Gene3D G3DSA:2.60.40.2500 192 289 1.3E-11 T 13-10-2018 IPR038161 VirB9/CagX/TrbG, C-terminal domain superfamily Astex_3272 72f77499c77ac2be539d42343132fa73 199 SUPERFAMILY SSF46689 6 74 1.9E-15 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Astex_3272 72f77499c77ac2be539d42343132fa73 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 5.0E-7 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Astex_3272 72f77499c77ac2be539d42343132fa73 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 5.0E-7 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Astex_3272 72f77499c77ac2be539d42343132fa73 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 4.9E-13 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Astex_3272 72f77499c77ac2be539d42343132fa73 199 Gene3D G3DSA:1.10.357.10 2 186 2.8E-38 T 13-10-2018 Astex_0330 3b5c2e56fd2771ff1705acf203261a25 274 Pfam PF00574 Clp protease 75 202 9.5E-27 T 13-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA Astex_0330 3b5c2e56fd2771ff1705acf203261a25 274 PRINTS PR00127 Clp protease catalytic subunit P signature 182 201 6.9E-9 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Astex_0330 3b5c2e56fd2771ff1705acf203261a25 274 PRINTS PR00127 Clp protease catalytic subunit P signature 75 95 6.9E-9 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Astex_0330 3b5c2e56fd2771ff1705acf203261a25 274 PRINTS PR00127 Clp protease catalytic subunit P signature 106 123 6.9E-9 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 Astex_0330 3b5c2e56fd2771ff1705acf203261a25 274 SUPERFAMILY SSF52096 30 204 6.18E-42 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Astex_0330 3b5c2e56fd2771ff1705acf203261a25 274 Gene3D G3DSA:3.90.226.10 34 220 3.5E-44 T 13-10-2018 Astex_2070 e3ef2b9f94851e817bdc7c8b64be0e86 363 Pfam PF05448 Acetyl xylan esterase (AXE1) 149 199 6.2E-5 T 13-10-2018 IPR008391 Acetyl xylan esterase Astex_2070 e3ef2b9f94851e817bdc7c8b64be0e86 363 Gene3D G3DSA:1.10.10.800 201 291 1.1E-118 T 13-10-2018 Astex_2070 e3ef2b9f94851e817bdc7c8b64be0e86 363 SUPERFAMILY SSF53474 19 362 2.48E-47 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_2070 e3ef2b9f94851e817bdc7c8b64be0e86 363 Gene3D G3DSA:3.40.50.1820 69 346 1.1E-118 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1331 9d764c7f7a65049c3ae25c222d5a89fd 280 Pfam PF03524 Conjugal transfer protein 26 239 1.3E-52 T 13-10-2018 IPR010258 Conjugal transfer, TrbG/VirB9/CagX Astex_1331 9d764c7f7a65049c3ae25c222d5a89fd 280 Gene3D G3DSA:2.60.40.2500 140 262 1.3E-21 T 13-10-2018 IPR038161 VirB9/CagX/TrbG, C-terminal domain superfamily Astex_0735 e72ba83919a74f2efd45bb407effe62a 370 Gene3D G3DSA:3.90.1860.10 9 366 1.3E-83 T 13-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 Astex_0735 e72ba83919a74f2efd45bb407effe62a 370 TIGRFAM TIGR03073 release_rtcB: release factor H-coupled RctB family protein 11 360 1.2E-130 T 13-10-2018 IPR017510 Release factor H-coupled RctB family protein Astex_0735 e72ba83919a74f2efd45bb407effe62a 370 SUPERFAMILY SSF103365 17 365 3.66E-91 T 13-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 Astex_0735 e72ba83919a74f2efd45bb407effe62a 370 Pfam PF01139 tRNA-splicing ligase RtcB 120 365 1.6E-53 T 13-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 Astex_0735 e72ba83919a74f2efd45bb407effe62a 370 Pfam PF01139 tRNA-splicing ligase RtcB 24 88 9.2E-9 T 13-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 Astex_2789 7f25db14da206f9324516a75506f6a63 79 Pfam PF00550 Phosphopantetheine attachment site 6 73 6.9E-11 T 13-10-2018 IPR009081 Phosphopantetheine binding ACP domain Astex_2789 7f25db14da206f9324516a75506f6a63 79 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 22.136 T 13-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 Astex_2789 7f25db14da206f9324516a75506f6a63 79 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 1 76 1.4E-32 T 13-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 Astex_2789 7f25db14da206f9324516a75506f6a63 79 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 34 76 0.005 T 13-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 Astex_2789 7f25db14da206f9324516a75506f6a63 79 SUPERFAMILY SSF47336 1 77 3.14E-22 T 13-10-2018 IPR036736 ACP-like superfamily Astex_2789 7f25db14da206f9324516a75506f6a63 79 Gene3D G3DSA:1.10.1200.10 1 79 6.3E-29 T 13-10-2018 IPR036736 ACP-like superfamily Astex_3267 f02ca379ab4546e3105a32e1ed0bff2b 319 TIGRFAM TIGR02098 MJ0042_CXXC: MJ0042 family finger-like domain 1 37 3.5E-14 T 13-10-2018 IPR011723 Zinc finger/thioredoxin putative Astex_3267 f02ca379ab4546e3105a32e1ed0bff2b 319 Pfam PF13717 zinc-ribbon domain 1 35 5.4E-11 T 13-10-2018 IPR011723 Zinc finger/thioredoxin putative Astex_1656 a496eacc187708d816d6c2b8344856b6 387 Gene3D G3DSA:3.40.640.10 3 251 1.8E-63 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Astex_1656 a496eacc187708d816d6c2b8344856b6 387 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 13 384 7.2E-87 T 13-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 Astex_1656 a496eacc187708d816d6c2b8344856b6 387 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 193 207 - T 13-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 Astex_1656 a496eacc187708d816d6c2b8344856b6 387 TIGRFAM TIGR01324 cysta_beta_ly_B: cystathionine beta-lyase 6 385 1.5E-133 T 13-10-2018 IPR006233 Cystathionine beta-lyase, bacterial GO:0004121|GO:0005737|GO:0006520 KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8 Astex_1656 a496eacc187708d816d6c2b8344856b6 387 PIRSF PIRSF001434 1 387 6.8E-110 T 13-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 Astex_1656 a496eacc187708d816d6c2b8344856b6 387 Gene3D G3DSA:3.90.1150.10 252 387 1.9E-35 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Astex_1656 a496eacc187708d816d6c2b8344856b6 387 SUPERFAMILY SSF53383 47 384 1.03E-89 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Astex_1761 118446b02cd25a0cee0b88e5be786299 140 SUPERFAMILY SSF82649 1 136 8.37E-33 T 13-10-2018 Astex_1761 118446b02cd25a0cee0b88e5be786299 140 Gene3D G3DSA:3.90.1010.10 1 136 1.4E-23 T 13-10-2018 Astex_1761 118446b02cd25a0cee0b88e5be786299 140 Pfam PF01592 NifU-like N terminal domain 6 123 1.3E-7 T 13-10-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 Astex_1501 bcf2d60a26ddec0961e008f0ac295648 263 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 262 5.4E-66 T 13-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 Astex_1501 bcf2d60a26ddec0961e008f0ac295648 263 ProSitePatterns PS00728 AP endonucleases family 1 signature 3. 214 225 - T 13-10-2018 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Reactome: R-HSA-110357|Reactome: R-HSA-110362|Reactome: R-HSA-110373|Reactome: R-HSA-5651801|Reactome: R-HSA-73930|Reactome: R-HSA-73933 Astex_1501 bcf2d60a26ddec0961e008f0ac295648 263 Gene3D G3DSA:3.60.10.10 1 263 4.7E-67 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily Astex_1501 bcf2d60a26ddec0961e008f0ac295648 263 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 261 1.3E-66 T 13-10-2018 Astex_1501 bcf2d60a26ddec0961e008f0ac295648 263 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 5 254 2.0E-18 T 13-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase Astex_1501 bcf2d60a26ddec0961e008f0ac295648 263 SUPERFAMILY SSF56219 1 262 2.36E-75 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily Astex_2149 af62167faf16160eed809d5ce3c923df 73 Gene3D G3DSA:1.10.1200.10 5 72 2.9E-9 T 13-10-2018 IPR036736 ACP-like superfamily Astex_2149 af62167faf16160eed809d5ce3c923df 73 SUPERFAMILY SSF47336 7 69 1.7E-7 T 13-10-2018 IPR036736 ACP-like superfamily Astex_2149 af62167faf16160eed809d5ce3c923df 73 Pfam PF00550 Phosphopantetheine attachment site 8 69 6.3E-6 T 13-10-2018 IPR009081 Phosphopantetheine binding ACP domain Astex_0582 09c8a81df45503a2c5cf793389f9b8d2 420 Gene3D G3DSA:2.120.10.30 124 411 4.1E-6 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like Astex_0582 09c8a81df45503a2c5cf793389f9b8d2 420 Gene3D G3DSA:1.25.40.10 35 98 2.1E-5 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_0582 09c8a81df45503a2c5cf793389f9b8d2 420 SUPERFAMILY SSF63829 131 353 2.81E-16 T 13-10-2018 Astex_0582 09c8a81df45503a2c5cf793389f9b8d2 420 SUPERFAMILY SSF48452 28 95 1.36E-5 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_2465 463b61c5d41aee1969c43a87e0669ac2 163 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 144 1.3E-4 T 13-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Astex_2465 463b61c5d41aee1969c43a87e0669ac2 163 Gene3D G3DSA:3.10.180.10 1 152 9.9E-14 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Astex_2465 463b61c5d41aee1969c43a87e0669ac2 163 SUPERFAMILY SSF54593 7 150 3.99E-15 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Astex_3382 507e389099dc0799ce11c1659bcd332d 500 Pfam PF04820 Tryptophan halogenase 1 452 1.3E-177 T 13-10-2018 IPR006905 Flavin-dependent halogenase Astex_3382 507e389099dc0799ce11c1659bcd332d 500 Gene3D G3DSA:3.50.50.60 1 489 8.8E-181 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_3382 507e389099dc0799ce11c1659bcd332d 500 PIRSF PIRSF011396 1 491 5.0E-183 T 13-10-2018 IPR033856 Flavin-dependent tryptophan halogenase Astex_3382 507e389099dc0799ce11c1659bcd332d 500 SUPERFAMILY SSF51905 1 414 1.52E-30 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_2835 0e26b285e4a53e713941f391ae21837b 160 Gene3D G3DSA:3.30.230.10 32 160 1.5E-49 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Astex_2835 0e26b285e4a53e713941f391ae21837b 160 Pfam PF00380 Ribosomal protein S9/S16 40 160 8.9E-46 T 13-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 Astex_2835 0e26b285e4a53e713941f391ae21837b 160 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 31 160 31.851 T 13-10-2018 IPR023035 Ribosomal protein S9, bacterial/plastid Astex_2835 0e26b285e4a53e713941f391ae21837b 160 SUPERFAMILY SSF54211 35 160 2.31E-46 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Astex_2485 96b3861afc4a74e610c4968e744cb593 241 TIGRFAM TIGR02780 TrbJ_Ti: P-type conjugative transfer protein TrbJ 12 240 4.1E-44 T 13-10-2018 IPR014147 Type IV conjugative transfer protein TrbJ Astex_3039 08edfbc612971ce2eebb9a55aeaaeb59 478 Pfam PF02913 FAD linked oxidases, C-terminal domain 230 475 3.9E-54 T 13-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 Astex_3039 08edfbc612971ce2eebb9a55aeaaeb59 478 Gene3D G3DSA:3.30.70.2190 229 350 1.2E-35 T 13-10-2018 Astex_3039 08edfbc612971ce2eebb9a55aeaaeb59 478 Gene3D G3DSA:3.30.70.2740 351 437 4.7E-28 T 13-10-2018 Astex_3039 08edfbc612971ce2eebb9a55aeaaeb59 478 SUPERFAMILY SSF55103 231 478 1.05E-51 T 13-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 Astex_3039 08edfbc612971ce2eebb9a55aeaaeb59 478 Gene3D G3DSA:3.30.43.10 8 104 1.2E-24 T 13-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 Astex_3039 08edfbc612971ce2eebb9a55aeaaeb59 478 SUPERFAMILY SSF56176 17 226 2.59E-68 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 Astex_3039 08edfbc612971ce2eebb9a55aeaaeb59 478 Gene3D G3DSA:3.30.465.10 107 226 9.5E-42 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 Astex_3039 08edfbc612971ce2eebb9a55aeaaeb59 478 Gene3D G3DSA:1.10.45.10 438 475 2.7E-9 T 13-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 Astex_3039 08edfbc612971ce2eebb9a55aeaaeb59 478 Pfam PF01565 FAD binding domain 55 188 5.2E-35 T 13-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 Astex_1953 bac2e6263fd3e5823826aa9b0f7916f9 243 Gene3D G3DSA:3.40.50.1360 5 243 2.6E-57 T 13-10-2018 Astex_1953 bac2e6263fd3e5823826aa9b0f7916f9 243 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 16 229 4.4E-46 T 13-10-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 Astex_1953 bac2e6263fd3e5823826aa9b0f7916f9 243 TIGRFAM TIGR01198 pgl: 6-phosphogluconolactonase 13 230 2.0E-43 T 13-10-2018 IPR005900 6-phosphogluconolactonase, DevB-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31 Astex_1953 bac2e6263fd3e5823826aa9b0f7916f9 243 SUPERFAMILY SSF100950 10 232 2.09E-42 T 13-10-2018 IPR037171 NagB/RpiA transferase-like Astex_2041 0e587e1fa422dd8fc70920d891d6d424 336 SUPERFAMILY SSF50022 5 116 6.55E-30 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 Astex_2041 0e587e1fa422dd8fc70920d891d6d424 336 Pfam PF00355 Rieske [2Fe-2S] domain 13 87 6.3E-18 T 13-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Astex_2041 0e587e1fa422dd8fc70920d891d6d424 336 SUPERFAMILY SSF55961 151 308 8.24E-11 T 13-10-2018 Astex_2041 0e587e1fa422dd8fc70920d891d6d424 336 Gene3D G3DSA:2.102.10.10 10 130 2.1E-32 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 Astex_2742 0487d341a5706aa700c3a92f6b56688d 265 Pfam PF01145 SPFH domain / Band 7 family 40 207 1.3E-33 T 13-10-2018 IPR001107 Band 7 domain Astex_2742 0487d341a5706aa700c3a92f6b56688d 265 SUPERFAMILY SSF117892 65 197 2.09E-34 T 13-10-2018 IPR036013 Band 7/SPFH domain superfamily Astex_2742 0487d341a5706aa700c3a92f6b56688d 265 Gene3D G3DSA:3.30.479.30 62 193 3.0E-39 T 13-10-2018 Astex_2742 0487d341a5706aa700c3a92f6b56688d 265 SMART SM00244 34 191 7.5E-49 T 13-10-2018 IPR001107 Band 7 domain Astex_2742 0487d341a5706aa700c3a92f6b56688d 265 PRINTS PR00721 Stomatin signature 41 63 1.3E-52 T 13-10-2018 IPR001972 Stomatin family GO:0016020 Astex_2742 0487d341a5706aa700c3a92f6b56688d 265 PRINTS PR00721 Stomatin signature 167 185 1.3E-52 T 13-10-2018 IPR001972 Stomatin family GO:0016020 Astex_2742 0487d341a5706aa700c3a92f6b56688d 265 PRINTS PR00721 Stomatin signature 88 109 1.3E-52 T 13-10-2018 IPR001972 Stomatin family GO:0016020 Astex_2742 0487d341a5706aa700c3a92f6b56688d 265 PRINTS PR00721 Stomatin signature 211 234 1.3E-52 T 13-10-2018 IPR001972 Stomatin family GO:0016020 Astex_2742 0487d341a5706aa700c3a92f6b56688d 265 PRINTS PR00721 Stomatin signature 143 166 1.3E-52 T 13-10-2018 IPR001972 Stomatin family GO:0016020 Astex_2742 0487d341a5706aa700c3a92f6b56688d 265 PRINTS PR00721 Stomatin signature 123 140 1.3E-52 T 13-10-2018 IPR001972 Stomatin family GO:0016020 Astex_2742 0487d341a5706aa700c3a92f6b56688d 265 PRINTS PR00721 Stomatin signature 186 207 1.3E-52 T 13-10-2018 IPR001972 Stomatin family GO:0016020 Astex_2532 b4d5e2165ddcd1d59c5519b86e72fff2 769 TIGRFAM TIGR02965 xanthine_xdhB: xanthine dehydrogenase, molybdopterin binding subunit 15 764 0.0 T 13-10-2018 IPR014309 Xanthine dehydrogenase, molybdopterin binding subunit GO:0030151 KEGG: 00230+1.17.1.4+1.17.3.2|KEGG: 00232+1.17.3.2|KEGG: 00983+1.17.3.2|MetaCyc: PWY-5497|MetaCyc: PWY-5695|MetaCyc: PWY-6538|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-6999 Astex_2532 b4d5e2165ddcd1d59c5519b86e72fff2 769 SMART SM01008 29 136 4.9E-46 T 13-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead Astex_2532 b4d5e2165ddcd1d59c5519b86e72fff2 769 SUPERFAMILY SSF54665 7 137 4.45E-41 T 13-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily Astex_2532 b4d5e2165ddcd1d59c5519b86e72fff2 769 Gene3D G3DSA:3.30.365.10 2 768 2.3E-271 T 13-10-2018 Astex_2532 b4d5e2165ddcd1d59c5519b86e72fff2 769 SUPERFAMILY SSF56003 136 766 1.83E-193 T 13-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 Astex_2532 b4d5e2165ddcd1d59c5519b86e72fff2 769 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 29 136 4.0E-27 T 13-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead Astex_2532 b4d5e2165ddcd1d59c5519b86e72fff2 769 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 154 697 4.3E-194 T 13-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 Astex_1514 da0e02cf5c8f9919caaf71ff61c44908 458 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 138 156 3.7E-29 T 13-10-2018 Astex_1514 da0e02cf5c8f9919caaf71ff61c44908 458 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 289 311 3.7E-29 T 13-10-2018 Astex_1514 da0e02cf5c8f9919caaf71ff61c44908 458 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 3.7E-29 T 13-10-2018 Astex_1514 da0e02cf5c8f9919caaf71ff61c44908 458 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 176 194 3.7E-29 T 13-10-2018 Astex_1514 da0e02cf5c8f9919caaf71ff61c44908 458 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 276 3.7E-29 T 13-10-2018 Astex_1514 da0e02cf5c8f9919caaf71ff61c44908 458 Gene3D G3DSA:3.50.50.60 150 267 2.1E-104 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_1514 da0e02cf5c8f9919caaf71ff61c44908 458 SUPERFAMILY SSF51905 2 332 2.83E-50 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_1514 da0e02cf5c8f9919caaf71ff61c44908 458 SUPERFAMILY SSF55424 341 453 2.23E-35 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 Astex_1514 da0e02cf5c8f9919caaf71ff61c44908 458 TIGRFAM TIGR01424 gluta_reduc_2: glutathione-disulfide reductase 4 453 9.0E-188 T 13-10-2018 IPR006324 Glutathione-disulphide reductase GO:0004362|GO:0006749|GO:0050660|GO:0050661|GO:0055114 KEGG: 00480+1.8.1.7|MetaCyc: PWY-4081 Astex_1514 da0e02cf5c8f9919caaf71ff61c44908 458 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 324 1.0E-62 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Astex_1514 da0e02cf5c8f9919caaf71ff61c44908 458 PIRSF PIRSF000350 2 449 1.4E-76 T 13-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 Astex_1514 da0e02cf5c8f9919caaf71ff61c44908 458 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 176 201 1.6E-63 T 13-10-2018 Astex_1514 da0e02cf5c8f9919caaf71ff61c44908 458 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 304 311 1.6E-63 T 13-10-2018 Astex_1514 da0e02cf5c8f9919caaf71ff61c44908 458 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 1.6E-63 T 13-10-2018 Astex_1514 da0e02cf5c8f9919caaf71ff61c44908 458 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 261 275 1.6E-63 T 13-10-2018 Astex_1514 da0e02cf5c8f9919caaf71ff61c44908 458 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 141 150 1.6E-63 T 13-10-2018 Astex_1514 da0e02cf5c8f9919caaf71ff61c44908 458 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 340 361 1.6E-63 T 13-10-2018 Astex_1514 da0e02cf5c8f9919caaf71ff61c44908 458 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 427 447 1.6E-63 T 13-10-2018 Astex_1514 da0e02cf5c8f9919caaf71ff61c44908 458 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 1.6E-63 T 13-10-2018 Astex_1514 da0e02cf5c8f9919caaf71ff61c44908 458 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 405 420 1.6E-63 T 13-10-2018 Astex_1514 da0e02cf5c8f9919caaf71ff61c44908 458 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 344 452 1.0E-33 T 13-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 Astex_1514 da0e02cf5c8f9919caaf71ff61c44908 458 Gene3D G3DSA:3.50.50.60 6 324 2.1E-104 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_1514 da0e02cf5c8f9919caaf71ff61c44908 458 Gene3D G3DSA:3.30.390.30 343 458 5.6E-40 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 Astex_1514 da0e02cf5c8f9919caaf71ff61c44908 458 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 40 50 - T 13-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 Astex_2744 7fb3561b21b54c3848b31bf4cbf82b58 189 ProSitePatterns PS01014 Transcription termination factor nusG signature. 171 180 - T 13-10-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site Astex_2744 7fb3561b21b54c3848b31bf4cbf82b58 189 Pfam PF00467 KOW motif 138 167 2.7E-5 T 13-10-2018 IPR005824 KOW Astex_2744 7fb3561b21b54c3848b31bf4cbf82b58 189 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 14 188 25.235 T 13-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 Astex_2744 7fb3561b21b54c3848b31bf4cbf82b58 189 Pfam PF02357 Transcription termination factor nusG 16 118 1.8E-28 T 13-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 Astex_2744 7fb3561b21b54c3848b31bf4cbf82b58 189 Gene3D G3DSA:2.30.30.30 129 187 5.8E-24 T 13-10-2018 IPR014722 Ribosomal protein L2, domain 2 Astex_2744 7fb3561b21b54c3848b31bf4cbf82b58 189 SMART SM00738 14 122 4.3E-51 T 13-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 Astex_2744 7fb3561b21b54c3848b31bf4cbf82b58 189 Gene3D G3DSA:3.30.70.940 9 128 1.9E-45 T 13-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 Astex_2744 7fb3561b21b54c3848b31bf4cbf82b58 189 SMART SM00739 134 161 0.003 T 13-10-2018 IPR005824 KOW Astex_2744 7fb3561b21b54c3848b31bf4cbf82b58 189 PRINTS PR00338 Transcription termination factor NUSG signature 164 180 1.4E-19 T 13-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 Astex_2744 7fb3561b21b54c3848b31bf4cbf82b58 189 PRINTS PR00338 Transcription termination factor NUSG signature 69 81 1.4E-19 T 13-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 Astex_2744 7fb3561b21b54c3848b31bf4cbf82b58 189 PRINTS PR00338 Transcription termination factor NUSG signature 146 161 1.4E-19 T 13-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 Astex_2744 7fb3561b21b54c3848b31bf4cbf82b58 189 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 17 187 5.5E-67 T 13-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 Astex_2744 7fb3561b21b54c3848b31bf4cbf82b58 189 SUPERFAMILY SSF82679 14 120 1.05E-39 T 13-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 Astex_2744 7fb3561b21b54c3848b31bf4cbf82b58 189 SUPERFAMILY SSF50104 134 187 7.3E-17 T 13-10-2018 IPR008991 Translation protein SH3-like domain superfamily Astex_0893 c91ce1c9a73a6ad9fc2258734578ed98 257 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 6 240 1.3E-52 T 13-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 Astex_0893 c91ce1c9a73a6ad9fc2258734578ed98 257 Gene3D G3DSA:3.30.70.660 107 244 7.4E-44 T 13-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 Astex_0893 c91ce1c9a73a6ad9fc2258734578ed98 257 Pfam PF01416 tRNA pseudouridine synthase 144 246 9.6E-28 T 13-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 Astex_0893 c91ce1c9a73a6ad9fc2258734578ed98 257 Pfam PF01416 tRNA pseudouridine synthase 8 104 1.6E-7 T 13-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 Astex_0893 c91ce1c9a73a6ad9fc2258734578ed98 257 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 245 32.006 T 13-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 Astex_0893 c91ce1c9a73a6ad9fc2258734578ed98 257 SUPERFAMILY SSF55120 1 248 5.04E-79 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 Astex_0893 c91ce1c9a73a6ad9fc2258734578ed98 257 Gene3D G3DSA:3.30.70.580 1 106 9.8E-31 T 13-10-2018 Astex_0893 c91ce1c9a73a6ad9fc2258734578ed98 257 PIRSF PIRSF001430 1 256 2.7E-70 T 13-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 Astex_2564 ef4c8dd84d28408641a54518aa7a2dbc 600 Gene3D G3DSA:3.40.50.300 3 188 2.3E-71 T 13-10-2018 Astex_2564 ef4c8dd84d28408641a54518aa7a2dbc 600 Pfam PF00009 Elongation factor Tu GTP binding domain 6 184 8.0E-52 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Astex_2564 ef4c8dd84d28408641a54518aa7a2dbc 600 SUPERFAMILY SSF54980 295 373 8.63E-19 T 13-10-2018 IPR035647 EF-G domain III/V-like Astex_2564 ef4c8dd84d28408641a54518aa7a2dbc 600 Pfam PF03144 Elongation factor Tu domain 2 208 278 8.5E-9 T 13-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 Astex_2564 ef4c8dd84d28408641a54518aa7a2dbc 600 SUPERFAMILY SSF52540 1 230 3.65E-54 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2564 ef4c8dd84d28408641a54518aa7a2dbc 600 SUPERFAMILY SSF54980 402 496 6.23E-24 T 13-10-2018 IPR035647 EF-G domain III/V-like Astex_2564 ef4c8dd84d28408641a54518aa7a2dbc 600 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 45 60 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site Astex_2564 ef4c8dd84d28408641a54518aa7a2dbc 600 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 177 3.2E-18 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Astex_2564 ef4c8dd84d28408641a54518aa7a2dbc 600 Pfam PF00679 Elongation factor G C-terminus 402 487 4.8E-20 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like Astex_2564 ef4c8dd84d28408641a54518aa7a2dbc 600 Hamap MF_00071 Elongation factor 4 [lepA]. 1 600 307.384 T 13-10-2018 IPR006297 Elongation factor 4 GO:0005525 Astex_2564 ef4c8dd84d28408641a54518aa7a2dbc 600 Gene3D G3DSA:2.40.30.10 189 288 8.5E-33 T 13-10-2018 Astex_2564 ef4c8dd84d28408641a54518aa7a2dbc 600 PRINTS PR00315 GTP-binding elongation factor signature 9 22 1.6E-13 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Astex_2564 ef4c8dd84d28408641a54518aa7a2dbc 600 PRINTS PR00315 GTP-binding elongation factor signature 52 60 1.6E-13 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Astex_2564 ef4c8dd84d28408641a54518aa7a2dbc 600 PRINTS PR00315 GTP-binding elongation factor signature 93 104 1.6E-13 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Astex_2564 ef4c8dd84d28408641a54518aa7a2dbc 600 PRINTS PR00315 GTP-binding elongation factor signature 129 138 1.6E-13 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Astex_2564 ef4c8dd84d28408641a54518aa7a2dbc 600 PRINTS PR00315 GTP-binding elongation factor signature 77 87 1.6E-13 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 Astex_2564 ef4c8dd84d28408641a54518aa7a2dbc 600 Gene3D G3DSA:3.30.70.870 289 370 2.7E-35 T 13-10-2018 Astex_2564 ef4c8dd84d28408641a54518aa7a2dbc 600 Gene3D G3DSA:3.30.70.2570 482 556 3.4E-34 T 13-10-2018 IPR038363 LepA, C-terminal domain superfamily Astex_2564 ef4c8dd84d28408641a54518aa7a2dbc 600 TIGRFAM TIGR01393 lepA: elongation factor 4 6 598 4.4E-297 T 13-10-2018 IPR006297 Elongation factor 4 GO:0005525 Astex_2564 ef4c8dd84d28408641a54518aa7a2dbc 600 Gene3D G3DSA:3.30.70.3380 371 481 2.6E-41 T 13-10-2018 Astex_2564 ef4c8dd84d28408641a54518aa7a2dbc 600 Pfam PF06421 GTP-binding protein LepA C-terminus 490 596 1.7E-49 T 13-10-2018 IPR013842 GTP-binding protein LepA, C-terminal Astex_2564 ef4c8dd84d28408641a54518aa7a2dbc 600 SMART SM00838 401 492 0.005 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like Astex_0556 8bac8ea9ebbbe4a19a8c6c7a58018908 1591 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1535 1545 5.3E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_0556 8bac8ea9ebbbe4a19a8c6c7a58018908 1591 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1569 1582 5.3E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_0556 8bac8ea9ebbbe4a19a8c6c7a58018908 1591 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1546 1564 5.3E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_0556 8bac8ea9ebbbe4a19a8c6c7a58018908 1591 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1517 1531 5.3E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_0556 8bac8ea9ebbbe4a19a8c6c7a58018908 1591 Gene3D G3DSA:3.30.450.40 1166 1349 2.1E-26 T 13-10-2018 IPR029016 GAF-like domain superfamily Astex_0556 8bac8ea9ebbbe4a19a8c6c7a58018908 1591 SUPERFAMILY SSF55781 1174 1341 2.18E-19 T 13-10-2018 Astex_0556 8bac8ea9ebbbe4a19a8c6c7a58018908 1591 SUPERFAMILY SSF47384 1360 1430 2.55E-7 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Astex_0556 8bac8ea9ebbbe4a19a8c6c7a58018908 1591 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1476 1583 1.0E-17 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_0556 8bac8ea9ebbbe4a19a8c6c7a58018908 1591 SUPERFAMILY SSF56112 71 164 1.01E-15 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily Astex_0556 8bac8ea9ebbbe4a19a8c6c7a58018908 1591 Gene3D G3DSA:3.30.565.10 1435 1586 2.4E-36 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_0556 8bac8ea9ebbbe4a19a8c6c7a58018908 1591 SMART SM00387 1476 1585 1.3E-29 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_0556 8bac8ea9ebbbe4a19a8c6c7a58018908 1591 SUPERFAMILY SSF55874 1423 1584 1.27E-33 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_0556 8bac8ea9ebbbe4a19a8c6c7a58018908 1591 Gene3D G3DSA:1.10.287.130 1369 1431 1.5E-16 T 13-10-2018 Astex_0556 8bac8ea9ebbbe4a19a8c6c7a58018908 1591 SMART SM00065 1186 1336 2.2E-8 T 13-10-2018 IPR003018 GAF domain GO:0005515 Astex_0556 8bac8ea9ebbbe4a19a8c6c7a58018908 1591 Pfam PF13185 GAF domain 1181 1327 3.3E-9 T 13-10-2018 IPR003018 GAF domain GO:0005515 Astex_0556 8bac8ea9ebbbe4a19a8c6c7a58018908 1591 Pfam PF00512 His Kinase A (phospho-acceptor) domain 1365 1430 1.0E-8 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_0556 8bac8ea9ebbbe4a19a8c6c7a58018908 1591 SUPERFAMILY SSF52540 200 466 1.68E-10 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0556 8bac8ea9ebbbe4a19a8c6c7a58018908 1591 Gene3D G3DSA:1.10.510.10 47 176 1.2E-15 T 13-10-2018 Astex_0556 8bac8ea9ebbbe4a19a8c6c7a58018908 1591 SMART SM00388 1364 1434 2.1E-7 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_0556 8bac8ea9ebbbe4a19a8c6c7a58018908 1591 Pfam PF13191 AAA ATPase domain 204 384 2.4E-24 T 13-10-2018 Astex_0264 28cfe0c8cf605dd90931a002aa38c6d2 91 SUPERFAMILY SSF51344 4 84 4.84E-23 T 13-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_0264 28cfe0c8cf605dd90931a002aa38c6d2 91 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 10 83 8.0E-21 T 13-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_0264 28cfe0c8cf605dd90931a002aa38c6d2 91 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 5 86 3.6E-25 T 13-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_0264 28cfe0c8cf605dd90931a002aa38c6d2 91 Gene3D G3DSA:2.60.15.10 1 83 1.3E-30 T 13-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_0264 28cfe0c8cf605dd90931a002aa38c6d2 91 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 5 83 9.9E-27 T 13-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_0264 28cfe0c8cf605dd90931a002aa38c6d2 91 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 3 89 12.419 T 13-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_1692 1a31753e45bffd1912ab33837797a628 542 SUPERFAMILY SSF52540 2 262 1.57E-45 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1692 1a31753e45bffd1912ab33837797a628 542 Pfam PF00005 ABC transporter 19 190 3.8E-23 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_1692 1a31753e45bffd1912ab33837797a628 542 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Astex_1692 1a31753e45bffd1912ab33837797a628 542 Gene3D G3DSA:3.40.50.300 2 284 8.8E-62 T 13-10-2018 Astex_1692 1a31753e45bffd1912ab33837797a628 542 Gene3D G3DSA:3.40.50.300 287 536 2.6E-63 T 13-10-2018 Astex_1692 1a31753e45bffd1912ab33837797a628 542 Pfam PF00005 ABC transporter 342 471 1.8E-21 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_1692 1a31753e45bffd1912ab33837797a628 542 SMART SM00382 349 516 5.7E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_1692 1a31753e45bffd1912ab33837797a628 542 SMART SM00382 26 235 9.1E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_1692 1a31753e45bffd1912ab33837797a628 542 SUPERFAMILY SSF52540 304 525 8.04E-49 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1692 1a31753e45bffd1912ab33837797a628 542 ProSitePatterns PS00211 ABC transporters family signature. 443 457 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Astex_1692 1a31753e45bffd1912ab33837797a628 542 Pfam PF12848 ABC transporter 229 312 1.6E-23 T 13-10-2018 IPR032781 ABC-transporter extension domain Astex_1984 24739c75319ad1c6cce2cbc3e4b97ba0 242 Pfam PF01522 Polysaccharide deacetylase 55 169 2.0E-26 T 13-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 Astex_1984 24739c75319ad1c6cce2cbc3e4b97ba0 242 Gene3D G3DSA:3.20.20.370 43 241 1.3E-52 T 13-10-2018 Astex_1984 24739c75319ad1c6cce2cbc3e4b97ba0 242 SUPERFAMILY SSF88713 49 238 7.41E-51 T 13-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 Astex_2170 7253134eb54388f852589a0c776cbbc7 245 SUPERFAMILY SSF49899 26 243 1.04E-74 T 13-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily Astex_2170 7253134eb54388f852589a0c776cbbc7 245 Pfam PF09224 Domain of unknown function (DUF1961) 29 240 3.7E-101 T 13-10-2018 IPR015305 Protein of unknown function DUF1961 Astex_2170 7253134eb54388f852589a0c776cbbc7 245 Gene3D G3DSA:2.60.120.200 23 244 7.0E-80 T 13-10-2018 Astex_2170 7253134eb54388f852589a0c776cbbc7 245 ProDom PD113327 YESU 3D-STRUCTURE 31 243 8.0E-58 T 13-10-2018 IPR015305 Protein of unknown function DUF1961 Astex_0362 fd090c3e2ebfd293bd5ef90f52b9eb77 512 Gene3D G3DSA:1.25.40.10 8 223 3.0E-8 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_0362 fd090c3e2ebfd293bd5ef90f52b9eb77 512 SUPERFAMILY SSF48452 38 345 7.34E-9 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_2373 6ab72c7fffb50ef8d0c2dd15582b4725 342 PRINTS PR00069 Aldo-keto reductase signature 143 160 4.0E-5 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Astex_2373 6ab72c7fffb50ef8d0c2dd15582b4725 342 PRINTS PR00069 Aldo-keto reductase signature 112 130 4.0E-5 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Astex_2373 6ab72c7fffb50ef8d0c2dd15582b4725 342 Pfam PF00248 Aldo/keto reductase family 16 318 2.4E-67 T 13-10-2018 IPR023210 NADP-dependent oxidoreductase domain Astex_2373 6ab72c7fffb50ef8d0c2dd15582b4725 342 Gene3D G3DSA:3.20.20.100 1 339 5.8E-132 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily Astex_2373 6ab72c7fffb50ef8d0c2dd15582b4725 342 SUPERFAMILY SSF51430 1 324 1.44E-100 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily Astex_1942 07f1dd11104d37a2987c8b25edf768c0 306 SUPERFAMILY SSF53167 31 303 2.89E-45 T 13-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 Astex_1942 07f1dd11104d37a2987c8b25edf768c0 306 Gene3D G3DSA:3.40.50.1580 29 303 2.3E-59 T 13-10-2018 Astex_1942 07f1dd11104d37a2987c8b25edf768c0 306 Pfam PF01048 Phosphorylase superfamily 31 301 5.0E-46 T 13-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 Astex_2046 fb5c0eb8dab965c8e02d28eb18e755be 544 SUPERFAMILY SSF52518 358 533 5.9E-58 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold Astex_2046 fb5c0eb8dab965c8e02d28eb18e755be 544 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 3 168 1.1E-54 T 13-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 Astex_2046 fb5c0eb8dab965c8e02d28eb18e755be 544 Gene3D G3DSA:3.40.50.970 1 181 8.5E-64 T 13-10-2018 Astex_2046 fb5c0eb8dab965c8e02d28eb18e755be 544 SUPERFAMILY SSF52467 153 328 4.21E-33 T 13-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily Astex_2046 fb5c0eb8dab965c8e02d28eb18e755be 544 Gene3D G3DSA:3.40.50.1220 182 344 4.8E-33 T 13-10-2018 Astex_2046 fb5c0eb8dab965c8e02d28eb18e755be 544 SUPERFAMILY SSF52518 1 176 6.8E-54 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold Astex_2046 fb5c0eb8dab965c8e02d28eb18e755be 544 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 378 524 1.5E-40 T 13-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 Astex_2046 fb5c0eb8dab965c8e02d28eb18e755be 544 Gene3D G3DSA:3.40.50.970 345 541 7.7E-57 T 13-10-2018 Astex_2046 fb5c0eb8dab965c8e02d28eb18e755be 544 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 189 320 6.7E-26 T 13-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 Astex_1265 97df01d16eeb8046193a624438dac735 1006 Pfam PF00593 TonB dependent receptor 489 1005 9.8E-35 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_1265 97df01d16eeb8046193a624438dac735 1006 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 44 1006 1.2E-192 T 13-10-2018 IPR010104 Bacterial TonB-dependent receptor Astex_1265 97df01d16eeb8046193a624438dac735 1006 Gene3D G3DSA:2.40.170.20 300 586 6.4E-8 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_1265 97df01d16eeb8046193a624438dac735 1006 Gene3D G3DSA:2.40.170.20 611 1006 9.4E-40 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_1265 97df01d16eeb8046193a624438dac735 1006 Pfam PF07715 TonB-dependent Receptor Plug Domain 61 176 1.6E-16 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_1265 97df01d16eeb8046193a624438dac735 1006 Gene3D G3DSA:2.170.130.10 44 180 6.5E-17 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_1265 97df01d16eeb8046193a624438dac735 1006 SUPERFAMILY SSF56935 37 1006 5.49E-86 T 13-10-2018 Astex_1933 b7caaa33dfda7b4419016aada7a6b97d 228 SMART SM00382 22 201 1.6E-15 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_1933 b7caaa33dfda7b4419016aada7a6b97d 228 Pfam PF00005 ABC transporter 16 153 2.4E-25 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_1933 b7caaa33dfda7b4419016aada7a6b97d 228 Gene3D G3DSA:3.40.50.300 4 221 2.3E-49 T 13-10-2018 Astex_1933 b7caaa33dfda7b4419016aada7a6b97d 228 ProSitePatterns PS00211 ABC transporters family signature. 126 140 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Astex_1933 b7caaa33dfda7b4419016aada7a6b97d 228 SUPERFAMILY SSF52540 6 204 1.14E-48 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2028 f7a1c2387d3e00f1bb5a64de0a0c802b 534 SUPERFAMILY SSF52096 236 516 3.52E-88 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Astex_2028 f7a1c2387d3e00f1bb5a64de0a0c802b 534 SUPERFAMILY SSF52096 20 267 4.1E-68 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Astex_2028 f7a1c2387d3e00f1bb5a64de0a0c802b 534 Gene3D G3DSA:3.90.226.10 273 534 1.6E-103 T 13-10-2018 Astex_2028 f7a1c2387d3e00f1bb5a64de0a0c802b 534 Pfam PF01039 Carboxyl transferase domain 47 524 3.3E-146 T 13-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 Astex_2028 f7a1c2387d3e00f1bb5a64de0a0c802b 534 Gene3D G3DSA:3.90.226.10 1 271 3.4E-96 T 13-10-2018 Astex_3171 f7626c45854e13e23b13eb4ecc7cf7f5 239 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 191 207 1.7E-10 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Astex_3171 f7626c45854e13e23b13eb4ecc7cf7f5 239 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 191 1.7E-10 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Astex_3171 f7626c45854e13e23b13eb4ecc7cf7f5 239 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 207 219 1.7E-10 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Astex_3171 f7626c45854e13e23b13eb4ecc7cf7f5 239 Pfam PF00196 Bacterial regulatory proteins, luxR family 178 228 6.8E-15 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Astex_3171 f7626c45854e13e23b13eb4ecc7cf7f5 239 SUPERFAMILY SSF46894 167 237 7.14E-20 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Astex_3171 f7626c45854e13e23b13eb4ecc7cf7f5 239 SUPERFAMILY SSF52172 19 142 1.01E-24 T 13-10-2018 IPR011006 CheY-like superfamily Astex_3171 f7626c45854e13e23b13eb4ecc7cf7f5 239 Pfam PF00072 Response regulator receiver domain 25 134 4.1E-18 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_3171 f7626c45854e13e23b13eb4ecc7cf7f5 239 Gene3D G3DSA:3.40.50.12740 23 237 2.0E-53 T 13-10-2018 Astex_3171 f7626c45854e13e23b13eb4ecc7cf7f5 239 SMART SM00448 22 134 8.1E-23 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_3171 f7626c45854e13e23b13eb4ecc7cf7f5 239 SMART SM00421 174 231 1.0E-18 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Astex_2928 f8f554bc0c35018220aadc781a4884a1 100 SUPERFAMILY SSF47729 6 95 2.06E-27 T 13-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 Astex_2928 f8f554bc0c35018220aadc781a4884a1 100 SMART SM00411 6 95 3.7E-33 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Astex_2928 f8f554bc0c35018220aadc781a4884a1 100 Gene3D G3DSA:4.10.520.10 4 97 6.8E-29 T 13-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 Astex_2928 f8f554bc0c35018220aadc781a4884a1 100 Pfam PF00216 Bacterial DNA-binding protein 6 94 6.8E-27 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Astex_2928 f8f554bc0c35018220aadc781a4884a1 100 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 51 70 - T 13-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 Astex_2928 f8f554bc0c35018220aadc781a4884a1 100 Hamap MF_00380 Integration host factor subunit alpha [ihfA]. 4 100 24.891 T 13-10-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 Astex_2928 f8f554bc0c35018220aadc781a4884a1 100 PRINTS PR01727 Prokaryotic integration host factor signature 79 93 4.2E-12 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Astex_2928 f8f554bc0c35018220aadc781a4884a1 100 PRINTS PR01727 Prokaryotic integration host factor signature 45 60 4.2E-12 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Astex_2928 f8f554bc0c35018220aadc781a4884a1 100 PRINTS PR01727 Prokaryotic integration host factor signature 63 76 4.2E-12 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Astex_0613 4a6709d1fd982f774e0ecddfb5621e75 408 Pfam PF01339 CheB methylesterase 220 396 1.8E-53 T 13-10-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 Astex_0613 4a6709d1fd982f774e0ecddfb5621e75 408 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 14 403 34.083 T 13-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 Astex_0613 4a6709d1fd982f774e0ecddfb5621e75 408 Pfam PF00072 Response regulator receiver domain 16 120 1.0E-22 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_0613 4a6709d1fd982f774e0ecddfb5621e75 408 SUPERFAMILY SSF52172 12 147 3.98E-28 T 13-10-2018 IPR011006 CheY-like superfamily Astex_0613 4a6709d1fd982f774e0ecddfb5621e75 408 Gene3D G3DSA:3.40.50.12740 14 168 1.4E-28 T 13-10-2018 Astex_0613 4a6709d1fd982f774e0ecddfb5621e75 408 Gene3D G3DSA:3.40.50.180 214 400 1.4E-62 T 13-10-2018 IPR035909 Methylesterase CheB, C-terminal Astex_0613 4a6709d1fd982f774e0ecddfb5621e75 408 PIRSF PIRSF000876 11 406 3.9E-113 T 13-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 Astex_0613 4a6709d1fd982f774e0ecddfb5621e75 408 SUPERFAMILY SSF52738 215 402 9.29E-62 T 13-10-2018 IPR035909 Methylesterase CheB, C-terminal Astex_0613 4a6709d1fd982f774e0ecddfb5621e75 408 SMART SM00448 14 138 1.2E-22 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_2260 61efd494d1da88475fe26df16e3a00d7 352 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 335 1.2E-146 T 13-10-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 Astex_2260 61efd494d1da88475fe26df16e3a00d7 352 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 321 1.9E-94 T 13-10-2018 IPR016040 NAD(P)-binding domain Astex_2260 61efd494d1da88475fe26df16e3a00d7 352 SUPERFAMILY SSF51735 1 340 7.89E-93 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_2260 61efd494d1da88475fe26df16e3a00d7 352 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Astex_2260 61efd494d1da88475fe26df16e3a00d7 352 Gene3D G3DSA:3.40.50.720 2 320 1.3E-129 T 13-10-2018 Astex_2260 61efd494d1da88475fe26df16e3a00d7 352 Gene3D G3DSA:3.90.25.10 200 329 1.3E-129 T 13-10-2018 Astex_0119 187e3ff9984bbef9fa3bc8c553d2b31f 263 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 27 261 5.2E-110 T 13-10-2018 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 Astex_0119 187e3ff9984bbef9fa3bc8c553d2b31f 263 Gene3D G3DSA:3.40.50.300 25 263 3.1E-67 T 13-10-2018 Astex_0119 187e3ff9984bbef9fa3bc8c553d2b31f 263 SUPERFAMILY SSF52540 27 260 4.99E-64 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0119 187e3ff9984bbef9fa3bc8c553d2b31f 263 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Astex_0119 187e3ff9984bbef9fa3bc8c553d2b31f 263 SMART SM00382 51 244 1.2E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_0119 187e3ff9984bbef9fa3bc8c553d2b31f 263 Pfam PF00005 ABC transporter 43 188 1.6E-35 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_0119 187e3ff9984bbef9fa3bc8c553d2b31f 263 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 236 258 4.5E-10 T 13-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal Astex_0158 c8c149c141b6551ac40da2c519b54278 494 Pfam PF05872 Bacterial protein of unknown function (DUF853) 12 484 3.1E-227 T 13-10-2018 IPR033186 Helicase HerA-like C-terminal Astex_0158 c8c149c141b6551ac40da2c519b54278 494 Gene3D G3DSA:3.40.50.300 204 380 2.1E-20 T 13-10-2018 Astex_0158 c8c149c141b6551ac40da2c519b54278 494 Gene3D G3DSA:3.40.50.300 8 83 2.8E-8 T 13-10-2018 Astex_0158 c8c149c141b6551ac40da2c519b54278 494 SUPERFAMILY SSF52540 19 368 1.17E-53 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2519 aeee90b0e57a4b813e2fe19516699d9b 276 Gene3D G3DSA:2.60.120.10 18 272 2.6E-97 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Astex_2519 aeee90b0e57a4b813e2fe19516699d9b 276 Gene3D G3DSA:2.60.120.10 144 246 2.6E-97 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Astex_2519 aeee90b0e57a4b813e2fe19516699d9b 276 SUPERFAMILY SSF51182 5 276 1.33E-87 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily Astex_2519 aeee90b0e57a4b813e2fe19516699d9b 276 Pfam PF02678 Pirin 22 122 2.6E-35 T 13-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 Astex_2519 aeee90b0e57a4b813e2fe19516699d9b 276 Pfam PF05726 Pirin C-terminal cupin domain 177 276 2.0E-26 T 13-10-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 Astex_2519 aeee90b0e57a4b813e2fe19516699d9b 276 PIRSF PIRSF006232 3 276 6.0E-93 T 13-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 Astex_0136 19e3b25b7479c1be14b9de3e369042b4 350 Pfam PF06144 DNA polymerase III, delta subunit 24 197 1.8E-6 T 13-10-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 Astex_0136 19e3b25b7479c1be14b9de3e369042b4 350 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 23 342 9.8E-36 T 13-10-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 Astex_0136 19e3b25b7479c1be14b9de3e369042b4 350 SUPERFAMILY SSF52540 23 216 5.31E-6 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0136 19e3b25b7479c1be14b9de3e369042b4 350 Gene3D G3DSA:3.40.50.300 21 142 1.1E-6 T 13-10-2018 Astex_0136 19e3b25b7479c1be14b9de3e369042b4 350 Gene3D G3DSA:1.20.272.10 221 347 2.0E-11 T 13-10-2018 Astex_0136 19e3b25b7479c1be14b9de3e369042b4 350 SUPERFAMILY SSF48019 226 343 4.42E-12 T 13-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 Astex_1260 e9b42c142b58f62eb1e67e697f84dc13 592 SUPERFAMILY SSF52096 292 504 7.69E-40 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Astex_1260 e9b42c142b58f62eb1e67e697f84dc13 592 Gene3D G3DSA:3.90.226.10 287 517 3.5E-126 T 13-10-2018 Astex_1260 e9b42c142b58f62eb1e67e697f84dc13 592 SUPERFAMILY SSF52096 70 261 1.74E-17 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Astex_1260 e9b42c142b58f62eb1e67e697f84dc13 592 Gene3D G3DSA:3.90.226.10 72 286 3.5E-126 T 13-10-2018 Astex_1260 e9b42c142b58f62eb1e67e697f84dc13 592 PIRSF PIRSF001217 1 590 5.7E-151 T 13-10-2018 IPR004634 Peptidase S49, protease IV GO:0006465|GO:0008233|GO:0016021 Astex_1260 e9b42c142b58f62eb1e67e697f84dc13 592 Pfam PF01343 Peptidase family S49 115 270 1.8E-20 T 13-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 Astex_1260 e9b42c142b58f62eb1e67e697f84dc13 592 Pfam PF01343 Peptidase family S49 366 518 3.4E-45 T 13-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 Astex_1260 e9b42c142b58f62eb1e67e697f84dc13 592 Gene3D G3DSA:3.40.1750.10 167 474 3.5E-126 T 13-10-2018 Astex_1260 e9b42c142b58f62eb1e67e697f84dc13 592 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 307 517 4.1E-50 T 13-10-2018 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 Astex_1260 e9b42c142b58f62eb1e67e697f84dc13 592 TIGRFAM TIGR00705 SppA_67K: signal peptide peptidase SppA, 67K type 4 528 1.6E-97 T 13-10-2018 IPR004634 Peptidase S49, protease IV GO:0006465|GO:0008233|GO:0016021 Astex_1312 f6f39d781fda2ad1cf6c31d56320d15f 104 Gene3D G3DSA:1.10.10.10 2 81 6.6E-18 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1312 f6f39d781fda2ad1cf6c31d56320d15f 104 Pfam PF03965 Penicillinase repressor 6 101 7.6E-20 T 13-10-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 Astex_1312 f6f39d781fda2ad1cf6c31d56320d15f 104 SUPERFAMILY SSF46785 5 97 6.61E-17 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_1312 f6f39d781fda2ad1cf6c31d56320d15f 104 PIRSF PIRSF019455 2 103 1.7E-20 T 13-10-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 Astex_3389 c8aaa8455bb53f5eaa3a2a82db7836d3 927 Pfam PF07715 TonB-dependent Receptor Plug Domain 73 183 2.1E-13 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_3389 c8aaa8455bb53f5eaa3a2a82db7836d3 927 SUPERFAMILY SSF56935 41 927 2.53E-86 T 13-10-2018 Astex_3389 c8aaa8455bb53f5eaa3a2a82db7836d3 927 Gene3D G3DSA:2.170.130.10 43 188 5.7E-16 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_3389 c8aaa8455bb53f5eaa3a2a82db7836d3 927 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 50 927 1.7E-200 T 13-10-2018 IPR010104 Bacterial TonB-dependent receptor Astex_3389 c8aaa8455bb53f5eaa3a2a82db7836d3 927 Pfam PF00593 TonB dependent receptor 442 925 1.6E-35 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_3389 c8aaa8455bb53f5eaa3a2a82db7836d3 927 Gene3D G3DSA:2.40.170.20 250 927 1.4E-44 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_0606 1ac3f6d2fc6354e29ea7307225decb64 471 SUPERFAMILY SSF51126 2 405 3.01E-64 T 13-10-2018 IPR011050 Pectin lyase fold/virulence factor Astex_0606 1ac3f6d2fc6354e29ea7307225decb64 471 SMART SM00710 171 193 1200.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat Astex_0606 1ac3f6d2fc6354e29ea7307225decb64 471 SMART SM00710 194 215 9200.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat Astex_0606 1ac3f6d2fc6354e29ea7307225decb64 471 SMART SM00710 216 238 52.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat Astex_0606 1ac3f6d2fc6354e29ea7307225decb64 471 SMART SM00710 248 269 620.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat Astex_0606 1ac3f6d2fc6354e29ea7307225decb64 471 SMART SM00710 298 318 3500.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat Astex_0606 1ac3f6d2fc6354e29ea7307225decb64 471 Pfam PF12708 Pectate lyase superfamily protein 3 238 1.2E-11 T 13-10-2018 IPR024535 Pectate lyase superfamily protein Astex_0606 1ac3f6d2fc6354e29ea7307225decb64 471 Gene3D G3DSA:2.160.20.10 1 412 4.5E-89 T 13-10-2018 IPR012334 Pectin lyase fold Astex_2362 cb48dda5031fa0ae8b5a96984b151612 314 Pfam PF02685 Glucokinase 18 312 1.2E-65 T 13-10-2018 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0005536|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 Astex_2362 cb48dda5031fa0ae8b5a96984b151612 314 SUPERFAMILY SSF53067 15 312 3.02E-37 T 13-10-2018 Astex_2362 cb48dda5031fa0ae8b5a96984b151612 314 Gene3D G3DSA:3.40.367.20 100 299 4.6E-67 T 13-10-2018 Astex_2362 cb48dda5031fa0ae8b5a96984b151612 314 Gene3D G3DSA:3.30.420.40 16 310 4.6E-67 T 13-10-2018 Astex_0903 a3bcb97143c198c1e51660150675d023 402 SUPERFAMILY SSF141571 270 396 1.96E-26 T 13-10-2018 Astex_0903 a3bcb97143c198c1e51660150675d023 402 Gene3D G3DSA:2.160.20.80 137 237 2.5E-23 T 13-10-2018 Astex_0903 a3bcb97143c198c1e51660150675d023 402 Gene3D G3DSA:2.160.20.80 252 401 6.1E-29 T 13-10-2018 Astex_0903 a3bcb97143c198c1e51660150675d023 402 SUPERFAMILY SSF141571 39 122 6.02E-23 T 13-10-2018 Astex_0903 a3bcb97143c198c1e51660150675d023 402 SUPERFAMILY SSF141571 147 233 5.89E-21 T 13-10-2018 Astex_0903 a3bcb97143c198c1e51660150675d023 402 Gene3D G3DSA:2.160.20.80 20 136 2.0E-26 T 13-10-2018 Astex_0903 a3bcb97143c198c1e51660150675d023 402 Pfam PF00805 Pentapeptide repeats (8 copies) 174 213 8.7E-13 T 13-10-2018 IPR001646 Pentapeptide repeat Astex_0903 a3bcb97143c198c1e51660150675d023 402 Pfam PF00805 Pentapeptide repeats (8 copies) 74 112 4.1E-13 T 13-10-2018 IPR001646 Pentapeptide repeat Astex_0903 a3bcb97143c198c1e51660150675d023 402 Pfam PF00805 Pentapeptide repeats (8 copies) 311 348 2.4E-11 T 13-10-2018 IPR001646 Pentapeptide repeat Astex_0903 a3bcb97143c198c1e51660150675d023 402 Pfam PF00805 Pentapeptide repeats (8 copies) 359 390 1.4E-5 T 13-10-2018 IPR001646 Pentapeptide repeat Astex_3426 4f88143ca50c9aab246fc06668fd7e98 235 SMART SM00882 6 218 2.1E-90 T 13-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 Astex_3426 4f88143ca50c9aab246fc06668fd7e98 235 Pfam PF01144 Coenzyme A transferase 10 217 8.7E-76 T 13-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 Astex_3426 4f88143ca50c9aab246fc06668fd7e98 235 Gene3D G3DSA:3.40.1080.10 1 218 3.2E-93 T 13-10-2018 Astex_3426 4f88143ca50c9aab246fc06668fd7e98 235 SUPERFAMILY SSF100950 6 227 8.97E-86 T 13-10-2018 IPR037171 NagB/RpiA transferase-like Astex_3426 4f88143ca50c9aab246fc06668fd7e98 235 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 3 217 1.2E-77 T 13-10-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 Astex_3426 4f88143ca50c9aab246fc06668fd7e98 235 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 19 34 - T 13-10-2018 IPR004163 Coenzyme A transferase binding site GO:0008410 Reactome: R-HSA-77108 Astex_1522 4f88143ca50c9aab246fc06668fd7e98 235 SMART SM00882 6 218 2.1E-90 T 13-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 Astex_1522 4f88143ca50c9aab246fc06668fd7e98 235 Pfam PF01144 Coenzyme A transferase 10 217 8.7E-76 T 13-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 Astex_1522 4f88143ca50c9aab246fc06668fd7e98 235 Gene3D G3DSA:3.40.1080.10 1 218 3.2E-93 T 13-10-2018 Astex_1522 4f88143ca50c9aab246fc06668fd7e98 235 SUPERFAMILY SSF100950 6 227 8.97E-86 T 13-10-2018 IPR037171 NagB/RpiA transferase-like Astex_1522 4f88143ca50c9aab246fc06668fd7e98 235 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 3 217 1.2E-77 T 13-10-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 Astex_1522 4f88143ca50c9aab246fc06668fd7e98 235 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 19 34 - T 13-10-2018 IPR004163 Coenzyme A transferase binding site GO:0008410 Reactome: R-HSA-77108 Astex_2635 923f61422b5b3cd06b034c5c2f168fdc 216 Gene3D G3DSA:3.20.20.70 2 216 1.3E-61 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_2635 923f61422b5b3cd06b034c5c2f168fdc 216 TIGRFAM TIGR04508 queE_Cx14CxxC: 7-carboxy-7-deazaguanine synthase 3 216 2.7E-95 T 13-10-2018 IPR030977 7-carboxy-7-deazaguanine synthase, Cx14CxxC-type GO:0008616|GO:0046872 KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 Astex_2635 923f61422b5b3cd06b034c5c2f168fdc 216 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 3 216 28.65 T 13-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 Astex_2635 923f61422b5b3cd06b034c5c2f168fdc 216 SUPERFAMILY SSF102114 45 138 5.1E-8 T 13-10-2018 Astex_0522 9e517b075e5abeb36aea1ba47fb358f9 969 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 93 116 - T 13-10-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 Astex_0522 9e517b075e5abeb36aea1ba47fb358f9 969 SUPERFAMILY SSF63411 58 278 4.95E-45 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 Astex_0522 9e517b075e5abeb36aea1ba47fb358f9 969 Gene3D G3DSA:3.30.830.10 549 757 3.7E-11 T 13-10-2018 Astex_0522 9e517b075e5abeb36aea1ba47fb358f9 969 Gene3D G3DSA:3.30.830.10 321 486 5.4E-7 T 13-10-2018 Astex_0522 9e517b075e5abeb36aea1ba47fb358f9 969 Pfam PF00675 Insulinase (Peptidase family M16) 73 194 7.3E-26 T 13-10-2018 IPR011765 Peptidase M16, N-terminal Astex_0522 9e517b075e5abeb36aea1ba47fb358f9 969 Pfam PF05193 Peptidase M16 inactive domain 724 891 2.4E-13 T 13-10-2018 IPR007863 Peptidase M16, C-terminal Astex_0522 9e517b075e5abeb36aea1ba47fb358f9 969 Pfam PF05193 Peptidase M16 inactive domain 236 411 1.3E-12 T 13-10-2018 IPR007863 Peptidase M16, C-terminal Astex_0522 9e517b075e5abeb36aea1ba47fb358f9 969 Gene3D G3DSA:3.30.830.10 772 963 1.6E-24 T 13-10-2018 Astex_0522 9e517b075e5abeb36aea1ba47fb358f9 969 SUPERFAMILY SSF63411 784 964 1.19E-19 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 Astex_0522 9e517b075e5abeb36aea1ba47fb358f9 969 SUPERFAMILY SSF63411 543 758 1.1E-17 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 Astex_0522 9e517b075e5abeb36aea1ba47fb358f9 969 Gene3D G3DSA:3.30.830.10 57 284 2.3E-63 T 13-10-2018 Astex_1155 9eb03dc8dcd05d0aad7db7fe6d967d7f 357 Gene3D G3DSA:3.40.50.12710 1 350 1.4E-95 T 13-10-2018 IPR038375 Protein arginine methyltransferase NDUFAF7 superfamily Reactome: R-HSA-6799198 Astex_1155 9eb03dc8dcd05d0aad7db7fe6d967d7f 357 Pfam PF02636 Putative S-adenosyl-L-methionine-dependent methyltransferase 62 279 2.6E-54 T 13-10-2018 IPR003788 Protein arginine methyltransferase NDUFAF7 Reactome: R-HSA-6799198 Astex_1155 9eb03dc8dcd05d0aad7db7fe6d967d7f 357 SUPERFAMILY SSF53335 6 349 4.5E-96 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Astex_0023 a512c8df515ab11be8fc90713fd44356 331 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 2 329 1.2E-91 T 13-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 Astex_0023 a512c8df515ab11be8fc90713fd44356 331 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 194 204 1.9E-26 T 13-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 Astex_0023 a512c8df515ab11be8fc90713fd44356 331 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 13 29 1.9E-26 T 13-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 Astex_0023 a512c8df515ab11be8fc90713fd44356 331 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 64 83 1.9E-26 T 13-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 Astex_0023 a512c8df515ab11be8fc90713fd44356 331 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 140 161 1.9E-26 T 13-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 Astex_0023 a512c8df515ab11be8fc90713fd44356 331 Gene3D G3DSA:3.40.50.620 2 328 5.0E-124 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Astex_0023 a512c8df515ab11be8fc90713fd44356 331 SUPERFAMILY SSF52374 2 329 8.23E-87 T 13-10-2018 Astex_0023 a512c8df515ab11be8fc90713fd44356 331 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 1 330 38.102 T 13-10-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 Astex_0023 a512c8df515ab11be8fc90713fd44356 331 Gene3D G3DSA:1.10.240.10 185 297 5.0E-124 T 13-10-2018 Astex_0023 a512c8df515ab11be8fc90713fd44356 331 Pfam PF00579 tRNA synthetases class I (W and Y) 1 280 2.1E-73 T 13-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 Astex_3615 15b21271c4f47a10b92a8a6e68f0249b 303 Gene3D G3DSA:3.30.420.40 9 119 1.4E-65 T 13-10-2018 Astex_3615 15b21271c4f47a10b92a8a6e68f0249b 303 Gene3D G3DSA:3.30.420.40 120 266 1.4E-65 T 13-10-2018 Astex_3615 15b21271c4f47a10b92a8a6e68f0249b 303 SUPERFAMILY SSF53067 119 288 1.02E-35 T 13-10-2018 Astex_3615 15b21271c4f47a10b92a8a6e68f0249b 303 SUPERFAMILY SSF53067 8 116 1.08E-23 T 13-10-2018 Astex_3615 15b21271c4f47a10b92a8a6e68f0249b 303 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 11 288 7.1E-34 T 13-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 Astex_0433 79269cd4a41113ecff2befdfa1bed0c3 379 Gene3D G3DSA:2.70.70.10 247 374 8.4E-18 T 13-10-2018 IPR011055 Duplicated hybrid motif Astex_0433 79269cd4a41113ecff2befdfa1bed0c3 379 Pfam PF01551 Peptidase family M23 278 370 1.2E-14 T 13-10-2018 IPR016047 Peptidase M23 Astex_0433 79269cd4a41113ecff2befdfa1bed0c3 379 SUPERFAMILY SSF51261 231 371 7.32E-17 T 13-10-2018 IPR011055 Duplicated hybrid motif Astex_2065 21fcbf4489c0e3d9c2bee66a0f91ee6b 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 67 1.4E-16 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_2065 21fcbf4489c0e3d9c2bee66a0f91ee6b 302 Pfam PF03466 LysR substrate binding domain 92 297 3.5E-40 T 13-10-2018 IPR005119 LysR, substrate-binding Astex_2065 21fcbf4489c0e3d9c2bee66a0f91ee6b 302 Gene3D G3DSA:1.10.10.10 5 89 5.5E-19 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_2065 21fcbf4489c0e3d9c2bee66a0f91ee6b 302 Gene3D G3DSA:3.40.190.290 95 297 1.2E-53 T 13-10-2018 Astex_2065 21fcbf4489c0e3d9c2bee66a0f91ee6b 302 SUPERFAMILY SSF53850 87 297 1.81E-42 T 13-10-2018 Astex_2065 21fcbf4489c0e3d9c2bee66a0f91ee6b 302 SUPERFAMILY SSF46785 4 87 6.56E-19 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_1363 5f257707d619eeefec6676f53c054131 187 Gene3D G3DSA:2.40.128.20 18 184 1.8E-46 T 13-10-2018 IPR012674 Calycin Astex_1363 5f257707d619eeefec6676f53c054131 187 ProSitePatterns PS00213 Lipocalin signature. 43 54 - T 13-10-2018 IPR022272 Lipocalin family conserved site Astex_1363 5f257707d619eeefec6676f53c054131 187 PRINTS PR01171 Bacterial lipocalin signature 112 126 9.4E-18 T 13-10-2018 IPR002446 Lipocalin, bacterial GO:0005215 Astex_1363 5f257707d619eeefec6676f53c054131 187 PRINTS PR01171 Bacterial lipocalin signature 59 75 9.4E-18 T 13-10-2018 IPR002446 Lipocalin, bacterial GO:0005215 Astex_1363 5f257707d619eeefec6676f53c054131 187 PRINTS PR01171 Bacterial lipocalin signature 78 87 9.4E-18 T 13-10-2018 IPR002446 Lipocalin, bacterial GO:0005215 Astex_1363 5f257707d619eeefec6676f53c054131 187 PRINTS PR01171 Bacterial lipocalin signature 172 182 9.4E-18 T 13-10-2018 IPR002446 Lipocalin, bacterial GO:0005215 Astex_1363 5f257707d619eeefec6676f53c054131 187 PRINTS PR01171 Bacterial lipocalin signature 42 56 9.4E-18 T 13-10-2018 IPR002446 Lipocalin, bacterial GO:0005215 Astex_1363 5f257707d619eeefec6676f53c054131 187 PRINTS PR01171 Bacterial lipocalin signature 145 156 9.4E-18 T 13-10-2018 IPR002446 Lipocalin, bacterial GO:0005215 Astex_1363 5f257707d619eeefec6676f53c054131 187 Pfam PF08212 Lipocalin-like domain 42 183 6.4E-42 T 13-10-2018 IPR000566 Lipocalin/cytosolic fatty-acid binding domain Astex_1363 5f257707d619eeefec6676f53c054131 187 SUPERFAMILY SSF50814 31 184 1.18E-39 T 13-10-2018 IPR012674 Calycin Astex_1363 5f257707d619eeefec6676f53c054131 187 PIRSF PIRSF036893 5 187 6.4E-42 T 13-10-2018 IPR022271 Lipocalin, ApoD type Astex_3058 358f644283433822c17168412965fe19 244 TIGRFAM TIGR00608 radc: DNA repair protein RadC 22 243 2.4E-57 T 13-10-2018 IPR001405 Uncharacterised protein family UPF0758 Astex_3058 358f644283433822c17168412965fe19 244 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 193 198 - T 13-10-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site Astex_3058 358f644283433822c17168412965fe19 244 Gene3D G3DSA:3.40.140.10 120 243 1.7E-39 T 13-10-2018 Astex_3058 358f644283433822c17168412965fe19 244 Pfam PF04002 RadC-like JAB domain 123 240 8.1E-41 T 13-10-2018 IPR025657 RadC-like JAB domain Astex_3058 358f644283433822c17168412965fe19 244 SUPERFAMILY SSF47781 32 85 6.35E-5 T 13-10-2018 IPR010994 RuvA domain 2-like Astex_3058 358f644283433822c17168412965fe19 244 SUPERFAMILY SSF102712 132 210 4.32E-6 T 13-10-2018 Astex_1127 57f6ddeaf1ab59017a097e0eecc72570 207 Hamap MF_00052_B Ribonuclease HII [rnhB]. 13 192 34.409 T 13-10-2018 IPR022898 Ribonuclease HII GO:0004523 Astex_1127 57f6ddeaf1ab59017a097e0eecc72570 207 Pfam PF01351 Ribonuclease HII 15 192 1.0E-37 T 13-10-2018 IPR024567 Ribonuclease HII/HIII domain Astex_1127 57f6ddeaf1ab59017a097e0eecc72570 207 Gene3D G3DSA:3.30.420.10 3 206 5.4E-71 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Astex_1127 57f6ddeaf1ab59017a097e0eecc72570 207 SUPERFAMILY SSF53098 12 198 1.27E-66 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily Astex_2924 27a4dec1c5aa130a4828a9211b3f7582 209 Gene3D G3DSA:1.10.150.240 20 84 7.1E-37 T 13-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 Astex_2924 27a4dec1c5aa130a4828a9211b3f7582 209 SUPERFAMILY SSF56784 5 208 1.63E-40 T 13-10-2018 IPR036412 HAD-like superfamily Astex_2924 27a4dec1c5aa130a4828a9211b3f7582 209 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 181 1.0E-29 T 13-10-2018 Astex_2924 27a4dec1c5aa130a4828a9211b3f7582 209 Gene3D G3DSA:3.40.50.1000 9 201 7.1E-37 T 13-10-2018 IPR023214 HAD superfamily Astex_2123 31b9994b61e7628377209226a94dafe8 379 Gene3D G3DSA:2.40.50.100 244 363 8.3E-23 T 13-10-2018 Astex_2123 31b9994b61e7628377209226a94dafe8 379 SUPERFAMILY SSF50331 238 363 2.92E-25 T 13-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal Astex_2123 31b9994b61e7628377209226a94dafe8 379 SUPERFAMILY SSF52540 6 244 1.22E-85 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2123 31b9994b61e7628377209226a94dafe8 379 SMART SM00382 30 213 3.7E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_2123 31b9994b61e7628377209226a94dafe8 379 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Astex_2123 31b9994b61e7628377209226a94dafe8 379 Gene3D G3DSA:2.40.50.140 289 348 8.3E-23 T 13-10-2018 Astex_2123 31b9994b61e7628377209226a94dafe8 379 Pfam PF08402 TOBE domain 283 356 4.6E-6 T 13-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 Astex_2123 31b9994b61e7628377209226a94dafe8 379 Pfam PF00005 ABC transporter 22 163 5.9E-36 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_2123 31b9994b61e7628377209226a94dafe8 379 Gene3D G3DSA:3.40.50.300 1 240 4.2E-77 T 13-10-2018 Astex_0294 9b6ae31d5e406a997d05f26599cc06dd 161 Gene3D G3DSA:3.90.79.10 2 159 3.1E-44 T 13-10-2018 Astex_0294 9b6ae31d5e406a997d05f26599cc06dd 161 Hamap MF_00298 RNA pyrophosphohydrolase [rppH]. 2 159 32.029 T 13-10-2018 IPR022927 RNA pyrophosphohydrolase RppH Astex_0294 9b6ae31d5e406a997d05f26599cc06dd 161 SUPERFAMILY SSF55811 7 155 7.99E-32 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 Astex_0294 9b6ae31d5e406a997d05f26599cc06dd 161 ProSitePatterns PS00893 Nudix box signature. 42 63 - T 13-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 Astex_0294 9b6ae31d5e406a997d05f26599cc06dd 161 PRINTS PR00502 NUDIX hydrolase family signature 37 51 8.9E-8 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 Astex_0294 9b6ae31d5e406a997d05f26599cc06dd 161 PRINTS PR00502 NUDIX hydrolase family signature 51 66 8.9E-8 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 Astex_0294 9b6ae31d5e406a997d05f26599cc06dd 161 Pfam PF00293 NUDIX domain 8 148 6.1E-27 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 Astex_3578 02fd680d5c8e4076141a9d713fca16b8 327 Gene3D G3DSA:3.30.360.10 137 267 1.0E-91 T 13-10-2018 Astex_3578 02fd680d5c8e4076141a9d713fca16b8 327 TIGRFAM TIGR04380 myo_inos_iolG: inositol 2-dehydrogenase 1 326 2.0E-130 T 13-10-2018 IPR030827 Inositol 2-dehydrogenase Astex_3578 02fd680d5c8e4076141a9d713fca16b8 327 Gene3D G3DSA:3.40.50.720 4 315 1.0E-91 T 13-10-2018 Astex_3578 02fd680d5c8e4076141a9d713fca16b8 327 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 130 234 9.0E-8 T 13-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 Astex_3578 02fd680d5c8e4076141a9d713fca16b8 327 SUPERFAMILY SSF55347 126 286 1.31E-28 T 13-10-2018 Astex_3578 02fd680d5c8e4076141a9d713fca16b8 327 SUPERFAMILY SSF51735 3 141 7.48E-35 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_3578 02fd680d5c8e4076141a9d713fca16b8 327 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 103 2.7E-19 T 13-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 Astex_2148 517cfe34dc1746f65beccd05e2b1a951 353 Gene3D G3DSA:3.40.47.10 3 346 1.0E-100 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 Astex_2148 517cfe34dc1746f65beccd05e2b1a951 353 SUPERFAMILY SSF53901 10 340 2.0E-41 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 Astex_2148 517cfe34dc1746f65beccd05e2b1a951 353 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 253 339 4.6E-24 T 13-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 Astex_2148 517cfe34dc1746f65beccd05e2b1a951 353 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 111 182 7.4E-11 T 13-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 Astex_3410 870d297c3d09f61343f6dc6583636ad1 407 Gene3D G3DSA:1.10.287.130 187 248 1.1E-28 T 13-10-2018 Astex_3410 870d297c3d09f61343f6dc6583636ad1 407 Gene3D G3DSA:3.30.565.10 249 383 1.1E-28 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_3410 870d297c3d09f61343f6dc6583636ad1 407 Pfam PF13188 PAS domain 80 115 1.1E-6 T 13-10-2018 IPR000014 PAS domain Astex_3410 870d297c3d09f61343f6dc6583636ad1 407 PRINTS PR00344 Bacterial sensor protein C-terminal signature 362 380 1.9E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_3410 870d297c3d09f61343f6dc6583636ad1 407 PRINTS PR00344 Bacterial sensor protein C-terminal signature 333 347 1.9E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_3410 870d297c3d09f61343f6dc6583636ad1 407 PRINTS PR00344 Bacterial sensor protein C-terminal signature 351 361 1.9E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_3410 870d297c3d09f61343f6dc6583636ad1 407 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 296 404 5.7E-14 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_3410 870d297c3d09f61343f6dc6583636ad1 407 SMART SM00387 293 407 2.2E-20 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_3410 870d297c3d09f61343f6dc6583636ad1 407 SUPERFAMILY SSF55785 78 115 2.75E-5 T 13-10-2018 IPR035965 PAS domain superfamily Astex_3410 870d297c3d09f61343f6dc6583636ad1 407 SUPERFAMILY SSF55874 237 388 1.31E-27 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_2960 e060b68e6e4613e3872caa23f70f4f70 323 SUPERFAMILY SSF54814 204 320 1.44E-35 T 13-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 Astex_2960 e060b68e6e4613e3872caa23f70f4f70 323 SUPERFAMILY SSF52540 16 205 9.11E-43 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2960 e060b68e6e4613e3872caa23f70f4f70 323 TIGRFAM TIGR00436 era: GTP-binding protein Era 128 302 8.5E-37 T 13-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_2960 e060b68e6e4613e3872caa23f70f4f70 323 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 17 102 2.6E-14 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Astex_2960 e060b68e6e4613e3872caa23f70f4f70 323 Pfam PF01926 50S ribosome-binding GTPase 16 148 7.4E-23 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Astex_2960 e060b68e6e4613e3872caa23f70f4f70 323 Pfam PF07650 KH domain 231 307 4.7E-14 T 13-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_2960 e060b68e6e4613e3872caa23f70f4f70 323 Gene3D G3DSA:3.40.50.300 9 206 2.7E-42 T 13-10-2018 Astex_2960 e060b68e6e4613e3872caa23f70f4f70 323 Gene3D G3DSA:3.30.300.20 208 321 6.2E-34 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta Astex_2960 e060b68e6e4613e3872caa23f70f4f70 323 Hamap MF_00367 GTPase Era [era]. 11 319 32.069 T 13-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_3313 c1c093ea89845465328cb227b7994184 882 Gene3D G3DSA:2.60.40.1760 37 234 5.1E-26 T 13-10-2018 Astex_3313 c1c093ea89845465328cb227b7994184 882 SUPERFAMILY SSF51445 353 684 1.34E-58 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_3313 c1c093ea89845465328cb227b7994184 882 SUPERFAMILY SSF51011 686 767 1.01E-19 T 13-10-2018 Astex_3313 c1c093ea89845465328cb227b7994184 882 Gene3D G3DSA:2.60.40.1180 717 768 3.6E-15 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta Astex_3313 c1c093ea89845465328cb227b7994184 882 Gene3D G3DSA:3.20.20.80 350 716 5.9E-112 T 13-10-2018 Astex_3313 c1c093ea89845465328cb227b7994184 882 Pfam PF17137 Domain of unknown function (DUF5110) 789 854 5.6E-15 T 13-10-2018 IPR033403 Domain of unknown function DUF5110 Astex_3313 c1c093ea89845465328cb227b7994184 882 SUPERFAMILY SSF74650 38 215 1.04E-16 T 13-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 Astex_3313 c1c093ea89845465328cb227b7994184 882 Gene3D G3DSA:2.60.40.1180 769 881 6.3E-24 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta Astex_3313 c1c093ea89845465328cb227b7994184 882 Pfam PF01055 Glycosyl hydrolases family 31 345 772 2.3E-116 T 13-10-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 Astex_2337 17f613de0faec43cd93a698cbda71db3 320 SUPERFAMILY SSF53850 92 303 1.27E-38 T 13-10-2018 Astex_2337 17f613de0faec43cd93a698cbda71db3 320 Pfam PF03466 LysR substrate binding domain 92 299 5.4E-38 T 13-10-2018 IPR005119 LysR, substrate-binding Astex_2337 17f613de0faec43cd93a698cbda71db3 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 3.0E-6 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_2337 17f613de0faec43cd93a698cbda71db3 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 3.0E-6 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_2337 17f613de0faec43cd93a698cbda71db3 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 3.0E-6 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_2337 17f613de0faec43cd93a698cbda71db3 320 Gene3D G3DSA:3.40.190.10 164 267 1.8E-60 T 13-10-2018 Astex_2337 17f613de0faec43cd93a698cbda71db3 320 Gene3D G3DSA:3.40.190.10 104 295 1.8E-60 T 13-10-2018 Astex_2337 17f613de0faec43cd93a698cbda71db3 320 Gene3D G3DSA:1.10.10.10 8 97 3.0E-21 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_2337 17f613de0faec43cd93a698cbda71db3 320 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 68 1.3E-20 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_2337 17f613de0faec43cd93a698cbda71db3 320 SUPERFAMILY SSF46785 6 87 5.12E-20 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_3346 224f6c7e8ee61e0df76f65eed362d11e 499 Pfam PF13347 MFS/sugar transport protein 62 480 2.7E-100 T 13-10-2018 Astex_3346 224f6c7e8ee61e0df76f65eed362d11e 499 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 60 493 1.9E-112 T 13-10-2018 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 Astex_3346 224f6c7e8ee61e0df76f65eed362d11e 499 SUPERFAMILY SSF103473 60 477 1.96E-37 T 13-10-2018 IPR036259 MFS transporter superfamily Astex_3346 224f6c7e8ee61e0df76f65eed362d11e 499 Gene3D G3DSA:1.20.1250.20 271 482 1.8E-9 T 13-10-2018 Astex_3346 224f6c7e8ee61e0df76f65eed362d11e 499 Gene3D G3DSA:1.20.1250.20 58 257 2.1E-14 T 13-10-2018 Astex_0395 a15450c5afa5b40819d047ff0d92b971 94 Gene3D G3DSA:3.30.1340.10 7 93 1.1E-29 T 13-10-2018 IPR035895 HPr-like superfamily Astex_0395 a15450c5afa5b40819d047ff0d92b971 94 PRINTS PR00107 Phosphocarrier protein signature 18 34 1.3E-11 T 13-10-2018 IPR000032 Phosphocarrier protein HPr-like Astex_0395 a15450c5afa5b40819d047ff0d92b971 94 PRINTS PR00107 Phosphocarrier protein signature 43 58 1.3E-11 T 13-10-2018 IPR000032 Phosphocarrier protein HPr-like Astex_0395 a15450c5afa5b40819d047ff0d92b971 94 PRINTS PR00107 Phosphocarrier protein signature 58 75 1.3E-11 T 13-10-2018 IPR000032 Phosphocarrier protein HPr-like Astex_0395 a15450c5afa5b40819d047ff0d92b971 94 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 8 86 6.9E-27 T 13-10-2018 IPR000032 Phosphocarrier protein HPr-like Astex_0395 a15450c5afa5b40819d047ff0d92b971 94 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 18 25 - T 13-10-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site Astex_0395 a15450c5afa5b40819d047ff0d92b971 94 SUPERFAMILY SSF55594 8 93 4.71E-27 T 13-10-2018 IPR035895 HPr-like superfamily Astex_0395 a15450c5afa5b40819d047ff0d92b971 94 Pfam PF00381 PTS HPr component phosphorylation site 8 87 1.4E-26 T 13-10-2018 IPR000032 Phosphocarrier protein HPr-like Astex_3792 f3cee50dcc69e22e80952cb9fe18424c 168 SUPERFAMILY SSF51306 44 168 1.31E-21 T 13-10-2018 IPR036286 LexA/Signal peptidase-like superfamily Astex_3792 f3cee50dcc69e22e80952cb9fe18424c 168 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 55 165 7.2E-14 T 13-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 Astex_3792 f3cee50dcc69e22e80952cb9fe18424c 168 Gene3D G3DSA:2.10.109.10 59 168 2.6E-11 T 13-10-2018 Astex_3792 f3cee50dcc69e22e80952cb9fe18424c 168 Pfam PF10502 Signal peptidase, peptidase S26 40 168 4.4E-20 T 13-10-2018 IPR019533 Peptidase S26 Astex_3366 b79afaf4289e405b7d62cec917a078a0 880 Gene3D G3DSA:2.40.170.20 327 880 4.2E-31 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_3366 b79afaf4289e405b7d62cec917a078a0 880 Pfam PF00593 TonB dependent receptor 342 877 1.1E-18 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_3366 b79afaf4289e405b7d62cec917a078a0 880 Pfam PF07715 TonB-dependent Receptor Plug Domain 68 168 3.2E-11 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_3366 b79afaf4289e405b7d62cec917a078a0 880 Gene3D G3DSA:2.170.130.10 49 173 1.1E-10 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_3366 b79afaf4289e405b7d62cec917a078a0 880 SUPERFAMILY SSF56935 55 880 7.69E-70 T 13-10-2018 Astex_1184 4721dc59c2ae96605542fe6ce4f27995 294 SUPERFAMILY SSF56219 84 290 9.16E-22 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily Astex_1184 4721dc59c2ae96605542fe6ce4f27995 294 Gene3D G3DSA:3.60.10.10 85 291 4.1E-20 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily Astex_1184 4721dc59c2ae96605542fe6ce4f27995 294 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 97 283 7.8E-14 T 13-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase Astex_2961 698ce35b05f3e3bb3c1fc10576ab947d 242 ProSitePatterns PS00517 Ribonuclease III family signature. 56 64 - T 13-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 Astex_2961 698ce35b05f3e3bb3c1fc10576ab947d 242 SMART SM00535 31 167 6.6E-46 T 13-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 Astex_2961 698ce35b05f3e3bb3c1fc10576ab947d 242 SMART SM00358 173 240 3.7E-18 T 13-10-2018 IPR014720 Double-stranded RNA-binding domain Astex_2961 698ce35b05f3e3bb3c1fc10576ab947d 242 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 19 237 3.2E-68 T 13-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 Astex_2961 698ce35b05f3e3bb3c1fc10576ab947d 242 Gene3D G3DSA:1.10.1520.10 14 165 6.1E-42 T 13-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 Astex_2961 698ce35b05f3e3bb3c1fc10576ab947d 242 Hamap MF_00104 Ribonuclease 3 [rnc]. 19 236 26.563 T 13-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 Astex_2961 698ce35b05f3e3bb3c1fc10576ab947d 242 Pfam PF14622 Ribonuclease-III-like 29 154 7.5E-31 T 13-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 Astex_2961 698ce35b05f3e3bb3c1fc10576ab947d 242 Pfam PF00035 Double-stranded RNA binding motif 173 237 5.3E-14 T 13-10-2018 IPR014720 Double-stranded RNA-binding domain Astex_2961 698ce35b05f3e3bb3c1fc10576ab947d 242 SUPERFAMILY SSF69065 13 163 1.09E-42 T 13-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 Astex_2961 698ce35b05f3e3bb3c1fc10576ab947d 242 Gene3D G3DSA:3.30.160.20 170 240 3.3E-18 T 13-10-2018 Astex_2961 698ce35b05f3e3bb3c1fc10576ab947d 242 SUPERFAMILY SSF54768 129 239 1.34E-23 T 13-10-2018 Astex_3494 3fdb14184bbb30f7a4b44434cef30630 128 Pfam PF00072 Response regulator receiver domain 9 121 3.8E-29 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_3494 3fdb14184bbb30f7a4b44434cef30630 128 Gene3D G3DSA:3.40.50.2300 2 126 1.7E-36 T 13-10-2018 Astex_3494 3fdb14184bbb30f7a4b44434cef30630 128 SMART SM00448 7 121 6.3E-33 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_3494 3fdb14184bbb30f7a4b44434cef30630 128 SUPERFAMILY SSF52172 7 126 5.69E-35 T 13-10-2018 IPR011006 CheY-like superfamily Astex_2792 c94323d18add35a9f83c2a4b1cf6c1d2 292 Pfam PF08340 Domain of unknown function (DUF1732) 208 292 3.5E-31 T 13-10-2018 IPR013551 Domain of unknown function DUF1732 Astex_2792 c94323d18add35a9f83c2a4b1cf6c1d2 292 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 3 292 5.6E-62 T 13-10-2018 IPR005229 Conserved hypothetical protein CHP00255 Astex_2792 c94323d18add35a9f83c2a4b1cf6c1d2 292 Pfam PF03755 YicC-like family, N-terminal region 4 156 2.1E-35 T 13-10-2018 IPR013527 YicC-like, N-terminal Astex_3439 f47194833b1c1192c15f52b53bc53982 296 SUPERFAMILY SSF46626 210 295 4.52E-25 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Astex_3439 f47194833b1c1192c15f52b53bc53982 296 PIRSF PIRSF000006 6 296 2.9E-100 T 13-10-2018 IPR004678 Cytochrome c oxidase cbb3-type, subunit III Astex_3439 f47194833b1c1192c15f52b53bc53982 296 Gene3D G3DSA:1.20.58.1490 6 73 3.2E-20 T 13-10-2018 IPR038414 Cbb3-type cytochrome c oxidase subunit CcoP, N-terminal domain superfamily Astex_3439 f47194833b1c1192c15f52b53bc53982 296 Gene3D G3DSA:1.10.760.10 177 269 2.3E-62 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Astex_3439 f47194833b1c1192c15f52b53bc53982 296 PRINTS PR00605 Class IC cytochrome C signature 124 135 1.4E-7 T 13-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 Astex_3439 f47194833b1c1192c15f52b53bc53982 296 PRINTS PR00605 Class IC cytochrome C signature 267 289 1.4E-7 T 13-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 Astex_3439 f47194833b1c1192c15f52b53bc53982 296 TIGRFAM TIGR00782 ccoP: cytochrome c oxidase, cbb3-type, subunit III 10 296 2.3E-99 T 13-10-2018 IPR004678 Cytochrome c oxidase cbb3-type, subunit III Astex_3439 f47194833b1c1192c15f52b53bc53982 296 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 213 289 2.5E-14 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_3439 f47194833b1c1192c15f52b53bc53982 296 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 117 202 2.1E-10 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_3439 f47194833b1c1192c15f52b53bc53982 296 SUPERFAMILY SSF46626 35 205 6.5E-27 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Astex_3439 f47194833b1c1192c15f52b53bc53982 296 Pfam PF14715 N-terminal domain of cytochrome oxidase-cbb3, FixP 16 61 2.6E-23 T 13-10-2018 IPR032858 Cbb3-type cytochrome c oxidase subunit CcoP, N-terminal Astex_3439 f47194833b1c1192c15f52b53bc53982 296 Gene3D G3DSA:1.10.760.10 92 292 2.3E-62 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Astex_1122 8962e9b3f354e49a59bc6cfe10ec102a 150 Pfam PF05258 Protein of unknown function (DUF721) 17 90 8.8E-13 T 13-10-2018 IPR007922 Protein of unknown function DUF721/UPF0232 Astex_1122 8962e9b3f354e49a59bc6cfe10ec102a 150 PIRSF PIRSF032064 2 149 3.0E-34 T 13-10-2018 IPR010593 Protein of unknown function DUF1159 Astex_2534 21eeafe4747a712f2344054476cc6acb 339 Pfam PF00962 Adenosine/AMP deaminase 15 326 4.1E-72 T 13-10-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 Astex_2534 21eeafe4747a712f2344054476cc6acb 339 Gene3D G3DSA:3.20.20.140 7 338 6.4E-98 T 13-10-2018 Astex_2534 21eeafe4747a712f2344054476cc6acb 339 SUPERFAMILY SSF51556 10 337 2.72E-80 T 13-10-2018 IPR032466 Metal-dependent hydrolase Astex_2534 21eeafe4747a712f2344054476cc6acb 339 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 15 329 1.3E-114 T 13-10-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 Astex_2534 21eeafe4747a712f2344054476cc6acb 339 Hamap MF_01962 Adenine deaminase. 11 323 83.368 T 13-10-2018 IPR028892 Adenine deaminase type 2 GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 Astex_0394 e5ddd69a0bca8e15d15c248a0b797c83 261 SMART SM00895 121 243 2.6E-17 T 13-10-2018 IPR011711 GntR, C-terminal Astex_0394 e5ddd69a0bca8e15d15c248a0b797c83 261 Gene3D G3DSA:1.20.120.530 119 256 8.3E-23 T 13-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal Astex_0394 e5ddd69a0bca8e15d15c248a0b797c83 261 Gene3D G3DSA:1.10.10.10 26 101 1.3E-14 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_0394 e5ddd69a0bca8e15d15c248a0b797c83 261 Pfam PF00392 Bacterial regulatory proteins, gntR family 33 92 4.4E-12 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Astex_0394 e5ddd69a0bca8e15d15c248a0b797c83 261 SUPERFAMILY SSF48008 119 247 1.75E-22 T 13-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal Astex_0394 e5ddd69a0bca8e15d15c248a0b797c83 261 SUPERFAMILY SSF46785 29 96 1.46E-14 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_0394 e5ddd69a0bca8e15d15c248a0b797c83 261 SMART SM00345 33 92 3.4E-9 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Astex_0394 e5ddd69a0bca8e15d15c248a0b797c83 261 Pfam PF07729 FCD domain 122 242 6.4E-19 T 13-10-2018 IPR011711 GntR, C-terminal Astex_2005 e5ddd69a0bca8e15d15c248a0b797c83 261 SMART SM00895 121 243 2.6E-17 T 13-10-2018 IPR011711 GntR, C-terminal Astex_2005 e5ddd69a0bca8e15d15c248a0b797c83 261 Gene3D G3DSA:1.20.120.530 119 256 8.3E-23 T 13-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal Astex_2005 e5ddd69a0bca8e15d15c248a0b797c83 261 Gene3D G3DSA:1.10.10.10 26 101 1.3E-14 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_2005 e5ddd69a0bca8e15d15c248a0b797c83 261 Pfam PF00392 Bacterial regulatory proteins, gntR family 33 92 4.4E-12 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Astex_2005 e5ddd69a0bca8e15d15c248a0b797c83 261 SUPERFAMILY SSF48008 119 247 1.75E-22 T 13-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal Astex_2005 e5ddd69a0bca8e15d15c248a0b797c83 261 SUPERFAMILY SSF46785 29 96 1.46E-14 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_2005 e5ddd69a0bca8e15d15c248a0b797c83 261 SMART SM00345 33 92 3.4E-9 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Astex_2005 e5ddd69a0bca8e15d15c248a0b797c83 261 Pfam PF07729 FCD domain 122 242 6.4E-19 T 13-10-2018 IPR011711 GntR, C-terminal Astex_3788 b78032295a30abcd54c18c997ff92437 148 Pfam PF09676 Type IV conjugative transfer system lipoprotein (TraV) 67 116 2.0E-10 T 13-10-2018 IPR014118 Type IV conjugative transfer system protein TraV Astex_2766 aca21e430054e59a8a58612f29f1b5d5 148 TIGRFAM TIGR02945 SUF_assoc: FeS assembly SUF system protein 51 148 3.2E-46 T 13-10-2018 IPR014291 SUF system FeS cluster assembly associated Astex_2766 aca21e430054e59a8a58612f29f1b5d5 148 SUPERFAMILY SSF117916 52 146 9.48E-30 T 13-10-2018 IPR034904 Fe-S cluster assembly domain superfamily Astex_2766 aca21e430054e59a8a58612f29f1b5d5 148 Gene3D G3DSA:3.30.300.130 45 147 2.3E-33 T 13-10-2018 IPR034904 Fe-S cluster assembly domain superfamily Astex_2766 aca21e430054e59a8a58612f29f1b5d5 148 Pfam PF01883 Iron-sulfur cluster assembly protein 53 125 2.9E-16 T 13-10-2018 IPR002744 MIP18 family-like Astex_1480 88e34d007e894be435eb722d48b22bdf 441 Pfam PF15515 MvaI/BcnI restriction endonuclease family 179 431 8.2E-33 T 13-10-2018 IPR029127 MvaI/BcnI restriction endonuclease Astex_1480 88e34d007e894be435eb722d48b22bdf 441 Gene3D G3DSA:3.40.210.20 180 380 6.9E-12 T 13-10-2018 Astex_1480 88e34d007e894be435eb722d48b22bdf 441 Gene3D G3DSA:2.60.40.2490 249 423 6.9E-12 T 13-10-2018 Astex_2066 d7b97ab98a310d3bd81a9f72bb473d8a 313 Pfam PF00248 Aldo/keto reductase family 5 296 5.8E-61 T 13-10-2018 IPR023210 NADP-dependent oxidoreductase domain Astex_2066 d7b97ab98a310d3bd81a9f72bb473d8a 313 Gene3D G3DSA:3.20.20.100 1 312 1.1E-73 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily Astex_2066 d7b97ab98a310d3bd81a9f72bb473d8a 313 PRINTS PR00069 Aldo-keto reductase signature 99 117 1.5E-5 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Astex_2066 d7b97ab98a310d3bd81a9f72bb473d8a 313 PRINTS PR00069 Aldo-keto reductase signature 127 144 1.5E-5 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 Astex_2066 d7b97ab98a310d3bd81a9f72bb473d8a 313 SUPERFAMILY SSF51430 3 294 2.23E-70 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily Astex_0574 62b898fa1d099b7995ead8f06e45b70e 459 Gene3D G3DSA:1.10.287.130 199 299 1.4E-10 T 13-10-2018 Astex_0574 62b898fa1d099b7995ead8f06e45b70e 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 411 429 5.6E-5 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_0574 62b898fa1d099b7995ead8f06e45b70e 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 378 392 5.6E-5 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_0574 62b898fa1d099b7995ead8f06e45b70e 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 396 406 5.6E-5 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_0574 62b898fa1d099b7995ead8f06e45b70e 459 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 345 449 1.1E-15 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_0574 62b898fa1d099b7995ead8f06e45b70e 459 SMART SM00388 233 298 3.3E-5 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_0574 62b898fa1d099b7995ead8f06e45b70e 459 SUPERFAMILY SSF47384 217 298 1.04E-10 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Astex_0574 62b898fa1d099b7995ead8f06e45b70e 459 SUPERFAMILY SSF55874 305 446 2.1E-27 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_0574 62b898fa1d099b7995ead8f06e45b70e 459 Gene3D G3DSA:3.30.565.10 306 451 2.2E-27 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_0574 62b898fa1d099b7995ead8f06e45b70e 459 SMART SM00387 344 451 9.3E-27 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_1961 291e96b9bb6bdc68279032a822419d78 305 SUPERFAMILY SSF103481 203 300 3.53E-6 T 13-10-2018 Astex_1961 291e96b9bb6bdc68279032a822419d78 305 Pfam PF00892 EamA-like transporter family 7 141 4.4E-11 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Astex_1961 291e96b9bb6bdc68279032a822419d78 305 SUPERFAMILY SSF103481 46 145 5.1E-8 T 13-10-2018 Astex_1395 fa39f81a20dffcb1cf5b87613f2505c5 275 SUPERFAMILY SSF52374 3 270 8.04E-76 T 13-10-2018 Astex_1395 fa39f81a20dffcb1cf5b87613f2505c5 275 PRINTS PR00987 Glutamyl-tRNA synthetase signature 184 194 5.6E-16 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Astex_1395 fa39f81a20dffcb1cf5b87613f2505c5 275 PRINTS PR00987 Glutamyl-tRNA synthetase signature 20 31 5.6E-16 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Astex_1395 fa39f81a20dffcb1cf5b87613f2505c5 275 PRINTS PR00987 Glutamyl-tRNA synthetase signature 200 208 5.6E-16 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Astex_1395 fa39f81a20dffcb1cf5b87613f2505c5 275 PRINTS PR00987 Glutamyl-tRNA synthetase signature 6 18 5.6E-16 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Astex_1395 fa39f81a20dffcb1cf5b87613f2505c5 275 PRINTS PR00987 Glutamyl-tRNA synthetase signature 35 48 5.6E-16 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Astex_1395 fa39f81a20dffcb1cf5b87613f2505c5 275 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 9 20 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Astex_1395 fa39f81a20dffcb1cf5b87613f2505c5 275 Gene3D G3DSA:3.40.50.620 2 274 3.5E-79 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Astex_1395 fa39f81a20dffcb1cf5b87613f2505c5 275 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 171 265 1.8E-14 T 13-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 Astex_1395 fa39f81a20dffcb1cf5b87613f2505c5 275 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 4 109 5.1E-32 T 13-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 Astex_2015 be853ec106c380523bc05900cbb05d50 164 Pfam PF03100 CcmE 11 134 1.9E-39 T 13-10-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004|GO:0020037 Astex_2015 be853ec106c380523bc05900cbb05d50 164 SUPERFAMILY SSF82093 35 140 2.35E-32 T 13-10-2018 IPR036127 CcmE-like superfamily GO:0005886|GO:0017003|GO:0017004 Astex_2015 be853ec106c380523bc05900cbb05d50 164 Gene3D G3DSA:2.40.50.140 35 141 3.1E-34 T 13-10-2018 Astex_2015 be853ec106c380523bc05900cbb05d50 164 Hamap MF_01959 Cytochrome c-type biogenesis protein CcmE [ccmE]. 7 145 27.781 T 13-10-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004|GO:0020037 Astex_1021 0f2642bbffc2cb2ea6219cf58579743c 292 Pfam PF13714 Phosphoenolpyruvate phosphomutase 8 252 1.1E-49 T 13-10-2018 Astex_1021 0f2642bbffc2cb2ea6219cf58579743c 292 SUPERFAMILY SSF51621 3 288 1.44E-98 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 Astex_1021 0f2642bbffc2cb2ea6219cf58579743c 292 Hamap MF_01939 2-methylisocitrate lyase [prpB]. 2 290 48.408 T 13-10-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 Astex_1021 0f2642bbffc2cb2ea6219cf58579743c 292 Gene3D G3DSA:3.20.20.60 1 292 7.8E-103 T 13-10-2018 Astex_1021 0f2642bbffc2cb2ea6219cf58579743c 292 TIGRFAM TIGR02317 prpB: methylisocitrate lyase 5 289 9.6E-125 T 13-10-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 Astex_1021 0f2642bbffc2cb2ea6219cf58579743c 292 ProSitePatterns PS00161 Isocitrate lyase signature. 119 124 - T 13-10-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824 Astex_0647 7c2b4fba74b4fff4c201846d8b939c3a 102 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 22 37 3.6E-10 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Astex_0647 7c2b4fba74b4fff4c201846d8b939c3a 102 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 69 84 3.6E-10 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Astex_0647 7c2b4fba74b4fff4c201846d8b939c3a 102 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 54 69 3.6E-10 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Astex_0647 7c2b4fba74b4fff4c201846d8b939c3a 102 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 41 52 3.6E-10 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Astex_0647 7c2b4fba74b4fff4c201846d8b939c3a 102 Pfam PF01022 Bacterial regulatory protein, arsR family 28 72 6.1E-11 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Astex_0647 7c2b4fba74b4fff4c201846d8b939c3a 102 SUPERFAMILY SSF46785 14 100 7.92E-24 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_0647 7c2b4fba74b4fff4c201846d8b939c3a 102 Gene3D G3DSA:1.10.10.10 4 102 4.0E-22 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_0647 7c2b4fba74b4fff4c201846d8b939c3a 102 SMART SM00418 20 98 4.2E-22 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Astex_3686 3c58656cc68d883822712fd99edbd784 369 Pfam PF02661 Fic/DOC family 112 223 9.6E-20 T 13-10-2018 IPR003812 Fido domain Astex_3686 3c58656cc68d883822712fd99edbd784 369 Pfam PF13776 Domain of unknown function (DUF4172) 3 84 7.7E-27 T 13-10-2018 IPR025230 Domain of unknown function DUF4172 Astex_3686 3c58656cc68d883822712fd99edbd784 369 SUPERFAMILY SSF140931 98 290 9.02E-35 T 13-10-2018 IPR036597 Fido-like domain superfamily Astex_3686 3c58656cc68d883822712fd99edbd784 369 Gene3D G3DSA:1.10.3290.10 35 286 1.7E-45 T 13-10-2018 IPR036597 Fido-like domain superfamily Astex_1527 6f357c2fc2aa87887e151bc73604ede8 269 Gene3D G3DSA:3.40.50.300 16 265 3.7E-62 T 13-10-2018 Astex_1527 6f357c2fc2aa87887e151bc73604ede8 269 Pfam PF00005 ABC transporter 32 181 2.1E-29 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_1527 6f357c2fc2aa87887e151bc73604ede8 269 SMART SM00382 40 229 2.5E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_1527 6f357c2fc2aa87887e151bc73604ede8 269 SUPERFAMILY SSF52540 16 240 8.15E-57 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0375 0546d115e72de76d0208a86ac857497c 272 PIRSF PIRSF015582 1 271 3.0E-65 T 13-10-2018 IPR011206 Citrate lyase beta subunit-like Astex_0375 0546d115e72de76d0208a86ac857497c 272 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 7 209 1.9E-39 T 13-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 Astex_0375 0546d115e72de76d0208a86ac857497c 272 SUPERFAMILY SSF51621 3 219 4.19E-60 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 Astex_0375 0546d115e72de76d0208a86ac857497c 272 Gene3D G3DSA:3.20.20.60 2 271 8.6E-80 T 13-10-2018 Astex_0891 a4ea505a7cb2636d885651888b8e7a34 178 SUPERFAMILY SSF56420 1 173 2.62E-61 T 13-10-2018 IPR036821 Peptide deformylase superfamily Astex_0891 a4ea505a7cb2636d885651888b8e7a34 178 Hamap MF_00163 Peptide deformylase [def]. 2 174 31.808 T 13-10-2018 IPR023635 Peptide deformylase Astex_0891 a4ea505a7cb2636d885651888b8e7a34 178 PRINTS PR01576 Peptide deformylase signature 113 131 1.1E-36 T 13-10-2018 IPR023635 Peptide deformylase Astex_0891 a4ea505a7cb2636d885651888b8e7a34 178 PRINTS PR01576 Peptide deformylase signature 101 112 1.1E-36 T 13-10-2018 IPR023635 Peptide deformylase Astex_0891 a4ea505a7cb2636d885651888b8e7a34 178 PRINTS PR01576 Peptide deformylase signature 34 63 1.1E-36 T 13-10-2018 IPR023635 Peptide deformylase Astex_0891 a4ea505a7cb2636d885651888b8e7a34 178 PRINTS PR01576 Peptide deformylase signature 132 161 1.1E-36 T 13-10-2018 IPR023635 Peptide deformylase Astex_0891 a4ea505a7cb2636d885651888b8e7a34 178 Gene3D G3DSA:3.90.45.10 1 178 2.2E-63 T 13-10-2018 IPR036821 Peptide deformylase superfamily Astex_0891 a4ea505a7cb2636d885651888b8e7a34 178 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 5 172 7.6E-48 T 13-10-2018 IPR023635 Peptide deformylase Astex_0891 a4ea505a7cb2636d885651888b8e7a34 178 PIRSF PIRSF004749 1 178 6.0E-56 T 13-10-2018 IPR023635 Peptide deformylase Astex_0891 a4ea505a7cb2636d885651888b8e7a34 178 Pfam PF01327 Polypeptide deformylase 4 164 2.3E-52 T 13-10-2018 IPR023635 Peptide deformylase Astex_2138 1b191a81e12799742e7b9901566b1b20 302 Pfam PF04909 Amidohydrolase 7 298 3.7E-39 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 Astex_2138 1b191a81e12799742e7b9901566b1b20 302 Gene3D G3DSA:3.20.20.140 5 301 5.0E-82 T 13-10-2018 Astex_2138 1b191a81e12799742e7b9901566b1b20 302 SUPERFAMILY SSF51556 5 298 4.35E-51 T 13-10-2018 IPR032466 Metal-dependent hydrolase Astex_1377 640009b524549e743316e2ea39df0bff 322 PIRSF PIRSF018266 1 321 5.3E-68 T 13-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component Astex_1377 640009b524549e743316e2ea39df0bff 322 Gene3D G3DSA:2.60.120.1440 104 233 7.4E-22 T 13-10-2018 Astex_1377 640009b524549e743316e2ea39df0bff 322 Pfam PF04773 FecR protein 112 204 1.9E-19 T 13-10-2018 IPR006860 FecR protein Astex_1377 640009b524549e743316e2ea39df0bff 322 Pfam PF16220 Domain of unknown function (DUF4880) 6 47 2.2E-6 T 13-10-2018 IPR032623 FecR, N-terminal Astex_1640 f77d33d8a8bf158183f233bd2d760ef5 760 Gene3D G3DSA:2.60.40.10 639 757 2.7E-31 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_1640 f77d33d8a8bf158183f233bd2d760ef5 760 PRINTS PR00133 Glycosyl hydrolase family 3 signature 215 231 9.6E-30 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_1640 f77d33d8a8bf158183f233bd2d760ef5 760 PRINTS PR00133 Glycosyl hydrolase family 3 signature 109 125 9.6E-30 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_1640 f77d33d8a8bf158183f233bd2d760ef5 760 PRINTS PR00133 Glycosyl hydrolase family 3 signature 138 157 9.6E-30 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_1640 f77d33d8a8bf158183f233bd2d760ef5 760 PRINTS PR00133 Glycosyl hydrolase family 3 signature 184 200 9.6E-30 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_1640 f77d33d8a8bf158183f233bd2d760ef5 760 PRINTS PR00133 Glycosyl hydrolase family 3 signature 285 303 9.6E-30 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_1640 f77d33d8a8bf158183f233bd2d760ef5 760 SMART SM01217 669 739 1.5E-23 T 13-10-2018 IPR026891 Fibronectin type III-like domain Astex_1640 f77d33d8a8bf158183f233bd2d760ef5 760 SUPERFAMILY SSF51445 39 379 1.16E-88 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_1640 f77d33d8a8bf158183f233bd2d760ef5 760 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 391 636 1.8E-55 T 13-10-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 Astex_1640 f77d33d8a8bf158183f233bd2d760ef5 760 SUPERFAMILY SSF52279 391 639 4.05E-50 T 13-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 Astex_1640 f77d33d8a8bf158183f233bd2d760ef5 760 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 108 354 2.5E-42 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_1640 f77d33d8a8bf158183f233bd2d760ef5 760 Pfam PF14310 Fibronectin type III-like domain 669 738 2.4E-18 T 13-10-2018 IPR026891 Fibronectin type III-like domain Astex_1640 f77d33d8a8bf158183f233bd2d760ef5 760 Gene3D G3DSA:3.40.50.1700 376 638 3.0E-70 T 13-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 Astex_1640 f77d33d8a8bf158183f233bd2d760ef5 760 Gene3D G3DSA:3.20.20.300 26 362 2.1E-96 T 13-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 Astex_2676 1e7eeb6f3947b2d0f5756b9ee679c804 67 SMART SM00357 3 67 1.7E-23 T 13-10-2018 IPR011129 Cold shock domain GO:0003676 Astex_2676 1e7eeb6f3947b2d0f5756b9ee679c804 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 13-10-2018 IPR019844 Cold-shock conserved site Astex_2676 1e7eeb6f3947b2d0f5756b9ee679c804 67 SUPERFAMILY SSF50249 1 66 2.04E-20 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Astex_2676 1e7eeb6f3947b2d0f5756b9ee679c804 67 PIRSF PIRSF002599 1 67 3.1E-20 T 13-10-2018 IPR012156 Cold shock, CspA GO:0003676 Astex_2676 1e7eeb6f3947b2d0f5756b9ee679c804 67 PRINTS PR00050 Cold shock protein signature 40 58 5.2E-12 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Astex_2676 1e7eeb6f3947b2d0f5756b9ee679c804 67 PRINTS PR00050 Cold shock protein signature 25 34 5.2E-12 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Astex_2676 1e7eeb6f3947b2d0f5756b9ee679c804 67 PRINTS PR00050 Cold shock protein signature 4 19 5.2E-12 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Astex_2676 1e7eeb6f3947b2d0f5756b9ee679c804 67 Pfam PF00313 'Cold-shock' DNA-binding domain 4 65 4.7E-24 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Astex_2676 1e7eeb6f3947b2d0f5756b9ee679c804 67 Gene3D G3DSA:2.40.50.140 2 66 3.2E-24 T 13-10-2018 Astex_0188 e1c536642763c1f1c530be83fe60a7e0 224 Pfam PF13599 Pentapeptide repeats (9 copies) 152 210 2.4E-8 T 13-10-2018 IPR001646 Pentapeptide repeat Astex_0188 e1c536642763c1f1c530be83fe60a7e0 224 Pfam PF13599 Pentapeptide repeats (9 copies) 46 116 1.6E-13 T 13-10-2018 IPR001646 Pentapeptide repeat Astex_0188 e1c536642763c1f1c530be83fe60a7e0 224 Gene3D G3DSA:2.160.20.100 63 224 5.6E-39 T 13-10-2018 Astex_0188 e1c536642763c1f1c530be83fe60a7e0 224 SUPERFAMILY SSF141571 74 222 6.97E-34 T 13-10-2018 Astex_0188 e1c536642763c1f1c530be83fe60a7e0 224 SUPERFAMILY SSF141571 24 99 1.94E-15 T 13-10-2018 Astex_3201 253822faadf2bd75eeee2dbe2d0abb35 404 Gene3D G3DSA:2.40.30.10 192 340 2.4E-61 T 13-10-2018 Astex_3201 253822faadf2bd75eeee2dbe2d0abb35 404 SUPERFAMILY SSF160996 196 338 3.27E-11 T 13-10-2018 Astex_3201 253822faadf2bd75eeee2dbe2d0abb35 404 PRINTS PR00419 Adrenodoxin reductase family signature 29 42 2.3E-7 T 13-10-2018 Astex_3201 253822faadf2bd75eeee2dbe2d0abb35 404 PRINTS PR00419 Adrenodoxin reductase family signature 6 28 2.3E-7 T 13-10-2018 Astex_3201 253822faadf2bd75eeee2dbe2d0abb35 404 Pfam PF03486 HI0933-like protein 6 391 2.9E-96 T 13-10-2018 Astex_3201 253822faadf2bd75eeee2dbe2d0abb35 404 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 7 391 1.0E-76 T 13-10-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like Astex_3201 253822faadf2bd75eeee2dbe2d0abb35 404 SUPERFAMILY SSF51905 4 396 1.64E-39 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_3201 253822faadf2bd75eeee2dbe2d0abb35 404 Gene3D G3DSA:1.10.8.260 271 323 2.4E-61 T 13-10-2018 IPR023166 HI0933-like insert domain superfamily Astex_3201 253822faadf2bd75eeee2dbe2d0abb35 404 Gene3D G3DSA:3.50.50.60 9 387 2.4E-61 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_3201 253822faadf2bd75eeee2dbe2d0abb35 404 TIGRFAM TIGR03862 flavo_PP4765: flavoprotein, TIGR03862 family 27 395 5.0E-145 T 13-10-2018 IPR022460 Conserved hyptotheical protein CHP03862, flavoprotein, PP4765 Astex_0432 e4b944b1bc1e79aaab2beda4a54db67a 488 SMART SM00228 96 167 2.9E-15 T 13-10-2018 IPR001478 PDZ domain GO:0005515 Astex_0432 e4b944b1bc1e79aaab2beda4a54db67a 488 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 48 366 9.8E-105 T 13-10-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 Astex_0432 e4b944b1bc1e79aaab2beda4a54db67a 488 SUPERFAMILY SSF50156 68 190 1.58E-23 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 Astex_0432 e4b944b1bc1e79aaab2beda4a54db67a 488 Gene3D G3DSA:2.30.42.10 96 183 9.6E-95 T 13-10-2018 Astex_0432 e4b944b1bc1e79aaab2beda4a54db67a 488 Pfam PF13180 PDZ domain 96 176 1.0E-14 T 13-10-2018 IPR001478 PDZ domain GO:0005515 Astex_0432 e4b944b1bc1e79aaab2beda4a54db67a 488 Gene3D G3DSA:3.90.226.10 184 356 9.6E-95 T 13-10-2018 Astex_0432 e4b944b1bc1e79aaab2beda4a54db67a 488 SUPERFAMILY SSF52096 34 363 1.41E-79 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Astex_0432 e4b944b1bc1e79aaab2beda4a54db67a 488 SMART SM00245 169 359 9.1E-75 T 13-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 Astex_0432 e4b944b1bc1e79aaab2beda4a54db67a 488 Pfam PF03572 Peptidase family S41 194 358 7.6E-56 T 13-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 Astex_0432 e4b944b1bc1e79aaab2beda4a54db67a 488 Gene3D G3DSA:3.30.750.44 38 334 9.6E-95 T 13-10-2018 Astex_2508 72d9b6777f31596cfeccf1f8ea50e44d 348 Pfam PF10005 zinc-ribbon domain 3 91 1.0E-31 T 13-10-2018 IPR011201 Zinc-ribbon domain, bacteria Astex_2508 72d9b6777f31596cfeccf1f8ea50e44d 348 Pfam PF15887 Putative zinc-binding metallo-peptidase 93 341 3.4E-97 T 13-10-2018 IPR031321 Uncharacterised conserved protein UCP012641, putative zinc-binding metallo-peptidase Astex_2508 72d9b6777f31596cfeccf1f8ea50e44d 348 PIRSF PIRSF012641 1 348 5.4E-138 T 13-10-2018 IPR031321 Uncharacterised conserved protein UCP012641, putative zinc-binding metallo-peptidase Astex_1226 d964d2baa282f14bdc79c961daa7cfab 826 Pfam PF00703 Glycosyl hydrolases family 2 258 348 8.5E-15 T 13-10-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_1226 d964d2baa282f14bdc79c961daa7cfab 826 PRINTS PR00132 Glycosyl hydrolase family 2 signature 360 374 2.1E-5 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_1226 d964d2baa282f14bdc79c961daa7cfab 826 PRINTS PR00132 Glycosyl hydrolase family 2 signature 449 464 2.1E-5 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_1226 d964d2baa282f14bdc79c961daa7cfab 826 SUPERFAMILY SSF49303 257 348 6.33E-14 T 13-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily Astex_1226 d964d2baa282f14bdc79c961daa7cfab 826 SUPERFAMILY SSF51445 353 635 4.82E-72 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_1226 d964d2baa282f14bdc79c961daa7cfab 826 Gene3D G3DSA:2.60.40.10 244 348 8.9E-21 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_1226 d964d2baa282f14bdc79c961daa7cfab 826 Pfam PF16355 Domain of unknown function (DUF4982) 650 707 4.6E-22 T 13-10-2018 IPR032311 Domain of unknown function DUF4982 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_1226 d964d2baa282f14bdc79c961daa7cfab 826 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 99 242 8.5E-11 T 13-10-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_1226 d964d2baa282f14bdc79c961daa7cfab 826 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 356 431 1.5E-17 T 13-10-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 Astex_1226 d964d2baa282f14bdc79c961daa7cfab 826 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 441 523 5.7E-12 T 13-10-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 Astex_1226 d964d2baa282f14bdc79c961daa7cfab 826 SUPERFAMILY SSF49785 46 242 7.23E-37 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_1226 d964d2baa282f14bdc79c961daa7cfab 826 Gene3D G3DSA:2.60.40.10 637 715 8.1E-31 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_1226 d964d2baa282f14bdc79c961daa7cfab 826 SUPERFAMILY SSF49373 718 819 3.4E-5 T 13-10-2018 IPR008964 Invasin/intimin cell-adhesion fragments Astex_1226 d964d2baa282f14bdc79c961daa7cfab 826 Gene3D G3DSA:2.60.40.10 718 826 1.7E-36 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_1226 d964d2baa282f14bdc79c961daa7cfab 826 Gene3D G3DSA:3.20.20.80 350 636 4.1E-98 T 13-10-2018 Astex_1226 d964d2baa282f14bdc79c961daa7cfab 826 Gene3D G3DSA:2.60.120.260 41 243 3.6E-39 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_0029 7f5a006d38aac8a60a1c5bd040fbd39e 137 Pfam PF01850 PIN domain 2 121 5.2E-15 T 13-10-2018 IPR002716 PIN domain Astex_0029 7f5a006d38aac8a60a1c5bd040fbd39e 137 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 133 10.67 T 13-10-2018 IPR022907 VapC family GO:0004540 Astex_0029 7f5a006d38aac8a60a1c5bd040fbd39e 137 Gene3D G3DSA:3.40.50.1010 1 135 1.7E-34 T 13-10-2018 Astex_0029 7f5a006d38aac8a60a1c5bd040fbd39e 137 SUPERFAMILY SSF88723 2 134 2.33E-26 T 13-10-2018 IPR029060 PIN-like domain superfamily Astex_3019 5ac4d107d1125cc077b7903186f761de 691 Pfam PF10459 Peptidase S46 29 689 5.3E-195 T 13-10-2018 IPR019500 Peptidase S46 GO:0008239|GO:0070009 Astex_3019 5ac4d107d1125cc077b7903186f761de 691 SUPERFAMILY SSF50494 59 646 1.66E-22 T 13-10-2018 IPR009003 Peptidase S1, PA clan Astex_3019 5ac4d107d1125cc077b7903186f761de 691 Gene3D G3DSA:2.40.10.10 603 646 1.9E-5 T 13-10-2018 Astex_1496 9ec5b7c60af132447cba5261fa36a3ab 246 SUPERFAMILY SSF110997 170 236 5.23E-8 T 13-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 Astex_1496 9ec5b7c60af132447cba5261fa36a3ab 246 Pfam PF05036 Sporulation related domain 171 242 3.9E-13 T 13-10-2018 IPR007730 Sporulation-like domain GO:0042834 Astex_2592 026b58d03863513d2addc827533dcdfe 539 Gene3D G3DSA:2.60.120.260 359 517 9.6E-27 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_2592 026b58d03863513d2addc827533dcdfe 539 SUPERFAMILY SSF49785 364 504 2.98E-6 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_2592 026b58d03863513d2addc827533dcdfe 539 Gene3D G3DSA:2.115.10.20 39 357 2.9E-76 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Astex_2592 026b58d03863513d2addc827533dcdfe 539 SUPERFAMILY SSF75005 45 346 3.0E-57 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Astex_2592 026b58d03863513d2addc827533dcdfe 539 Pfam PF04616 Glycosyl hydrolases family 43 46 340 1.5E-32 T 13-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 Astex_2316 e186f4e3614eb3a579e6e362fd9adaa0 291 Gene3D G3DSA:1.25.40.10 204 290 4.5E-20 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_2316 e186f4e3614eb3a579e6e362fd9adaa0 291 Pfam PF14561 Tetratricopeptide repeat 206 290 2.4E-24 T 13-10-2018 Astex_2316 e186f4e3614eb3a579e6e362fd9adaa0 291 Pfam PF14559 Tetratricopeptide repeat 133 198 1.7E-13 T 13-10-2018 Astex_2316 e186f4e3614eb3a579e6e362fd9adaa0 291 SUPERFAMILY SSF52833 6 111 2.96E-33 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Astex_2316 e186f4e3614eb3a579e6e362fd9adaa0 291 SUPERFAMILY SSF48452 126 276 5.91E-11 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_2316 e186f4e3614eb3a579e6e362fd9adaa0 291 ProSitePatterns PS00194 Thioredoxin family active site. 29 47 - T 13-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 Astex_2316 e186f4e3614eb3a579e6e362fd9adaa0 291 TIGRFAM TIGR01068 thioredoxin: thioredoxin 23 110 6.7E-30 T 13-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 Astex_2316 e186f4e3614eb3a579e6e362fd9adaa0 291 Pfam PF00085 Thioredoxin 11 110 4.9E-26 T 13-10-2018 IPR013766 Thioredoxin domain GO:0045454 Astex_2316 e186f4e3614eb3a579e6e362fd9adaa0 291 Gene3D G3DSA:3.40.30.10 4 111 6.7E-30 T 13-10-2018 Astex_2316 e186f4e3614eb3a579e6e362fd9adaa0 291 Gene3D G3DSA:1.25.40.10 121 203 1.3E-11 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_2316 e186f4e3614eb3a579e6e362fd9adaa0 291 PRINTS PR00421 Thioredoxin family signature 28 36 1.8E-5 T 13-10-2018 Astex_2316 e186f4e3614eb3a579e6e362fd9adaa0 291 PRINTS PR00421 Thioredoxin family signature 36 45 1.8E-5 T 13-10-2018 Astex_2316 e186f4e3614eb3a579e6e362fd9adaa0 291 PRINTS PR00421 Thioredoxin family signature 76 87 1.8E-5 T 13-10-2018 Astex_3398 a0d6eb54221b4796f078d43a5ac43cdb 409 Gene3D G3DSA:3.50.50.60 105 394 3.1E-30 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_3398 a0d6eb54221b4796f078d43a5ac43cdb 409 SUPERFAMILY SSF54373 268 354 4.84E-5 T 13-10-2018 Astex_3398 a0d6eb54221b4796f078d43a5ac43cdb 409 Gene3D G3DSA:3.50.50.60 2 77 2.1E-14 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_3398 a0d6eb54221b4796f078d43a5ac43cdb 409 Gene3D G3DSA:3.30.9.10 134 353 3.1E-30 T 13-10-2018 Astex_3398 a0d6eb54221b4796f078d43a5ac43cdb 409 Pfam PF01266 FAD dependent oxidoreductase 3 393 3.9E-48 T 13-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 Astex_3398 a0d6eb54221b4796f078d43a5ac43cdb 409 SUPERFAMILY SSF51905 3 401 1.29E-31 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_2381 000bcc5417410b44d5a5c53b964029f8 88 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 87 1.3E-22 T 13-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_2381 000bcc5417410b44d5a5c53b964029f8 88 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 16.399 T 13-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_2381 000bcc5417410b44d5a5c53b964029f8 88 Gene3D G3DSA:1.20.58.110 1 87 3.3E-27 T 13-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_2381 000bcc5417410b44d5a5c53b964029f8 88 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 21 78 8.0E-15 T 13-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_2381 000bcc5417410b44d5a5c53b964029f8 88 Pfam PF01649 Ribosomal protein S20 2 84 4.9E-25 T 13-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_2381 000bcc5417410b44d5a5c53b964029f8 88 SUPERFAMILY SSF46992 3 86 5.23E-28 T 13-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_1252 0124edf37c625a9a215df4a38a7f35ef 150 Pfam PF10768 Class II flagellar assembly regulator 13 147 3.4E-40 T 13-10-2018 IPR019704 Flagellar assembly regulator FliX, class II GO:0044781 Astex_1272 c58a5b24a27ba47f9c4271cddff86789 418 Hamap MF_01202 D-amino acid dehydrogenase [dadA]. 1 411 49.23 T 13-10-2018 IPR023080 D-amino acid dehydrogenase DadA GO:0008718|GO:0019478|GO:0055114 Astex_1272 c58a5b24a27ba47f9c4271cddff86789 418 Gene3D G3DSA:3.50.50.60 1 70 2.4E-11 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_1272 c58a5b24a27ba47f9c4271cddff86789 418 Gene3D G3DSA:3.30.9.10 134 362 1.5E-51 T 13-10-2018 Astex_1272 c58a5b24a27ba47f9c4271cddff86789 418 SUPERFAMILY SSF51905 1 416 5.83E-55 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_1272 c58a5b24a27ba47f9c4271cddff86789 418 Gene3D G3DSA:3.50.50.60 105 405 1.5E-51 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_1272 c58a5b24a27ba47f9c4271cddff86789 418 Pfam PF01266 FAD dependent oxidoreductase 2 398 1.1E-67 T 13-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 Astex_1272 c58a5b24a27ba47f9c4271cddff86789 418 SUPERFAMILY SSF54373 270 360 2.49E-15 T 13-10-2018 Astex_3795 191bd710323fa776d515325aa6bc891e 243 Pfam PF09673 Type-F conjugative transfer system pilin assembly protein 109 219 1.2E-28 T 13-10-2018 IPR019106 Type-F conjugative transfer system pilin assembly protein TrbC Astex_3795 191bd710323fa776d515325aa6bc891e 243 TIGRFAM TIGR02742 TrbC_Ftype: type-F conjugative transfer system pilin assembly protein TrbC 107 238 1.9E-29 T 13-10-2018 IPR014113 Type-F conjugative transfer system pilin assembly protein TrbC, subgroup Astex_3789 bd10a56eda4fb1b7f799ffaa2867146b 915 Pfam PF11130 F pilus assembly Type-IV secretion system for plasmid transfer 41 285 6.5E-57 T 13-10-2018 IPR025955 Type-IV secretion system protein TraC/Conjugative transfer ATPase Astex_3789 bd10a56eda4fb1b7f799ffaa2867146b 915 SMART SM00382 488 822 1.1E-4 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_3789 bd10a56eda4fb1b7f799ffaa2867146b 915 Gene3D G3DSA:1.10.8.730 547 664 2.5E-44 T 13-10-2018 Astex_3789 bd10a56eda4fb1b7f799ffaa2867146b 915 Pfam PF12846 AAA-like domain 483 747 9.6E-7 T 13-10-2018 Astex_3789 bd10a56eda4fb1b7f799ffaa2867146b 915 Gene3D G3DSA:3.40.50.300 471 792 2.5E-44 T 13-10-2018 Astex_3789 bd10a56eda4fb1b7f799ffaa2867146b 915 TIGRFAM TIGR02746 TraC-F-type: type-IV secretion system protein TraC 46 856 7.4E-175 T 13-10-2018 IPR014117 Type-IV secretion system protein TraC Astex_3789 bd10a56eda4fb1b7f799ffaa2867146b 915 SUPERFAMILY SSF52540 434 823 1.68E-39 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1170 f92bcfde0b9a186be73a483c8ab7e296 249 Pfam PF00106 short chain dehydrogenase 11 191 1.8E-34 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1170 f92bcfde0b9a186be73a483c8ab7e296 249 SUPERFAMILY SSF51735 8 243 8.05E-52 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_1170 f92bcfde0b9a186be73a483c8ab7e296 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 2.1E-15 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1170 f92bcfde0b9a186be73a483c8ab7e296 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 2.1E-15 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1170 f92bcfde0b9a186be73a483c8ab7e296 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.1E-15 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1170 f92bcfde0b9a186be73a483c8ab7e296 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.1E-15 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1170 f92bcfde0b9a186be73a483c8ab7e296 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 2.1E-15 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1170 f92bcfde0b9a186be73a483c8ab7e296 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Astex_1170 f92bcfde0b9a186be73a483c8ab7e296 249 Gene3D G3DSA:3.40.50.720 3 245 3.5E-52 T 13-10-2018 Astex_2188 e02f2800fcf22ac490aafcae90437698 721 Gene3D G3DSA:3.40.50.300 446 716 1.4E-63 T 13-10-2018 Astex_2188 e02f2800fcf22ac490aafcae90437698 721 Pfam PF02706 Chain length determinant protein 13 102 5.3E-9 T 13-10-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 Astex_2188 e02f2800fcf22ac490aafcae90437698 721 SUPERFAMILY SSF52540 522 701 2.13E-34 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2188 e02f2800fcf22ac490aafcae90437698 721 Pfam PF13807 G-rich domain on putative tyrosine kinase 379 451 1.1E-7 T 13-10-2018 IPR032807 Tyrosine kinase, G-rich domain Astex_2188 e02f2800fcf22ac490aafcae90437698 721 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 505 704 4.0E-35 T 13-10-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 Astex_2188 e02f2800fcf22ac490aafcae90437698 721 Pfam PF13614 AAA domain 523 677 2.3E-15 T 13-10-2018 IPR025669 AAA domain Astex_2478 f70152661cca38606d916260b83570e6 330 Pfam PF13593 SBF-like CPA transporter family (DUF4137) 13 323 4.3E-93 T 13-10-2018 IPR016833 Putative sodium bile acid cotransporter Astex_2478 f70152661cca38606d916260b83570e6 330 PIRSF PIRSF026166 5 327 6.4E-118 T 13-10-2018 IPR016833 Putative sodium bile acid cotransporter Astex_2478 f70152661cca38606d916260b83570e6 330 Gene3D G3DSA:1.20.1530.20 10 327 1.4E-26 T 13-10-2018 IPR038770 Sodium/solute symporter superfamily Astex_3229 c085d20261b2de55e12e5f34e26e259e 251 Gene3D G3DSA:1.10.238.10 43 141 7.9E-11 T 13-10-2018 Astex_3229 c085d20261b2de55e12e5f34e26e259e 251 Gene3D G3DSA:1.10.238.10 2 42 1.1E-5 T 13-10-2018 Astex_3229 c085d20261b2de55e12e5f34e26e259e 251 ProSitePatterns PS00018 EF-hand calcium-binding domain. 123 135 - T 13-10-2018 IPR018247 EF-Hand 1, calcium-binding site Astex_3229 c085d20261b2de55e12e5f34e26e259e 251 SMART SM00054 117 142 74.0 T 13-10-2018 IPR002048 EF-hand domain GO:0005509 Astex_3229 c085d20261b2de55e12e5f34e26e259e 251 SMART SM00054 155 183 9.3 T 13-10-2018 IPR002048 EF-hand domain GO:0005509 Astex_3229 c085d20261b2de55e12e5f34e26e259e 251 SMART SM00054 54 82 2.9 T 13-10-2018 IPR002048 EF-hand domain GO:0005509 Astex_3229 c085d20261b2de55e12e5f34e26e259e 251 SMART SM00054 14 42 4.6 T 13-10-2018 IPR002048 EF-hand domain GO:0005509 Astex_3229 c085d20261b2de55e12e5f34e26e259e 251 Gene3D G3DSA:1.10.238.10 142 186 2.3E-6 T 13-10-2018 Astex_3229 c085d20261b2de55e12e5f34e26e259e 251 Pfam PF13499 EF-hand domain pair 119 175 4.9E-9 T 13-10-2018 IPR002048 EF-hand domain GO:0005509 Astex_3229 c085d20261b2de55e12e5f34e26e259e 251 SUPERFAMILY SSF47473 16 175 1.37E-15 T 13-10-2018 IPR011992 EF-hand domain pair Astex_3229 c085d20261b2de55e12e5f34e26e259e 251 Pfam PF13202 EF hand 17 35 0.0013 T 13-10-2018 IPR002048 EF-hand domain GO:0005509 Astex_0849 2c2d0212539889f31cbc966ed67b5138 242 Pfam PF02107 Flagellar L-ring protein 57 241 2.2E-53 T 13-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 Astex_0849 2c2d0212539889f31cbc966ed67b5138 242 PRINTS PR01008 Flagellar L-ring protein signature 77 89 4.6E-27 T 13-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 Astex_0849 2c2d0212539889f31cbc966ed67b5138 242 PRINTS PR01008 Flagellar L-ring protein signature 182 198 4.6E-27 T 13-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 Astex_0849 2c2d0212539889f31cbc966ed67b5138 242 PRINTS PR01008 Flagellar L-ring protein signature 156 171 4.6E-27 T 13-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 Astex_0849 2c2d0212539889f31cbc966ed67b5138 242 PRINTS PR01008 Flagellar L-ring protein signature 219 233 4.6E-27 T 13-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 Astex_0849 2c2d0212539889f31cbc966ed67b5138 242 PRINTS PR01008 Flagellar L-ring protein signature 203 217 4.6E-27 T 13-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 Astex_0849 2c2d0212539889f31cbc966ed67b5138 242 Hamap MF_00415 Flagellar L-ring protein [flgH]. 1 240 23.676 T 13-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 Astex_2630 3baf1114df3656a9ab57d03fdbff0a88 383 Pfam PF00144 Beta-lactamase 28 353 7.9E-36 T 13-10-2018 IPR001466 Beta-lactamase-related Astex_2630 3baf1114df3656a9ab57d03fdbff0a88 383 Gene3D G3DSA:3.40.710.10 26 365 7.8E-54 T 13-10-2018 Astex_2630 3baf1114df3656a9ab57d03fdbff0a88 383 SUPERFAMILY SSF56601 27 353 2.64E-50 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like Astex_1662 d4babbef04d364b4f57488d4da0a770b 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 1.2E-25 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1662 d4babbef04d364b4f57488d4da0a770b 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.2E-25 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1662 d4babbef04d364b4f57488d4da0a770b 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 1.2E-25 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1662 d4babbef04d364b4f57488d4da0a770b 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 1.2E-25 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1662 d4babbef04d364b4f57488d4da0a770b 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 1.2E-25 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1662 d4babbef04d364b4f57488d4da0a770b 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 125 133 4.8E-10 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1662 d4babbef04d364b4f57488d4da0a770b 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 164 4.8E-10 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1662 d4babbef04d364b4f57488d4da0a770b 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 4.8E-10 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1662 d4babbef04d364b4f57488d4da0a770b 239 SUPERFAMILY SSF51735 1 221 4.0E-53 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_1662 d4babbef04d364b4f57488d4da0a770b 239 Gene3D G3DSA:3.40.50.720 1 233 6.0E-55 T 13-10-2018 Astex_1662 d4babbef04d364b4f57488d4da0a770b 239 Pfam PF00106 short chain dehydrogenase 6 187 3.3E-38 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1662 d4babbef04d364b4f57488d4da0a770b 239 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 132 160 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Astex_2683 291d160675c66b3d8e8c94385d559b1c 1248 SUPERFAMILY SSF75005 208 489 3.53E-21 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Astex_2683 291d160675c66b3d8e8c94385d559b1c 1248 Gene3D G3DSA:2.115.10.20 872 1236 2.5E-49 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Astex_2683 291d160675c66b3d8e8c94385d559b1c 1248 Gene3D G3DSA:2.115.10.20 190 483 7.7E-20 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Astex_2683 291d160675c66b3d8e8c94385d559b1c 1248 SUPERFAMILY SSF75005 881 1224 4.19E-26 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Astex_2683 291d160675c66b3d8e8c94385d559b1c 1248 Pfam PF04616 Glycosyl hydrolases family 43 211 413 7.6E-7 T 13-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 Astex_2683 291d160675c66b3d8e8c94385d559b1c 1248 Pfam PF04616 Glycosyl hydrolases family 43 956 1220 2.4E-17 T 13-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 Astex_0217 e8880c6b0e6ac9d3705f98b5bfd8575b 101 Pfam PF12840 Helix-turn-helix domain 5 60 1.6E-17 T 13-10-2018 Astex_0217 e8880c6b0e6ac9d3705f98b5bfd8575b 101 Gene3D G3DSA:1.10.10.10 1 85 5.2E-26 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_0217 e8880c6b0e6ac9d3705f98b5bfd8575b 101 SUPERFAMILY SSF46785 1 75 2.38E-24 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_0217 e8880c6b0e6ac9d3705f98b5bfd8575b 101 SMART SM00418 3 81 3.6E-23 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Astex_0217 e8880c6b0e6ac9d3705f98b5bfd8575b 101 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 8.3E-12 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Astex_0217 e8880c6b0e6ac9d3705f98b5bfd8575b 101 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 5 20 8.3E-12 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Astex_0217 e8880c6b0e6ac9d3705f98b5bfd8575b 101 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 37 52 8.3E-12 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Astex_2636 50eb7aaeb0ba5e3d90b47043e4f927d1 403 Gene3D G3DSA:3.30.420.40 49 181 2.0E-41 T 13-10-2018 Astex_2636 50eb7aaeb0ba5e3d90b47043e4f927d1 403 Gene3D G3DSA:3.30.420.150 184 392 1.3E-44 T 13-10-2018 Astex_2636 50eb7aaeb0ba5e3d90b47043e4f927d1 403 SUPERFAMILY SSF53067 60 180 2.03E-36 T 13-10-2018 Astex_2636 50eb7aaeb0ba5e3d90b47043e4f927d1 403 SUPERFAMILY SSF53067 187 390 9.07E-36 T 13-10-2018 Astex_2636 50eb7aaeb0ba5e3d90b47043e4f927d1 403 Pfam PF02541 Ppx/GppA phosphatase family 75 390 1.4E-45 T 13-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 Astex_3722 224aad5247532fd4ce62862b86ca4096 142 SUPERFAMILY SSF54523 38 137 2.15E-22 T 13-10-2018 Astex_3722 224aad5247532fd4ce62862b86ca4096 142 Pfam PF08334 Type II secretion system (T2SS), protein G 36 138 5.7E-29 T 13-10-2018 IPR013545 Type II secretion system protein G Astex_3722 224aad5247532fd4ce62862b86ca4096 142 Gene3D G3DSA:3.30.700.10 35 139 1.2E-25 T 13-10-2018 Astex_3722 224aad5247532fd4ce62862b86ca4096 142 PRINTS PR00813 Bacterial general secretion pathway protein G signature 12 37 2.2E-9 T 13-10-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 Astex_3722 224aad5247532fd4ce62862b86ca4096 142 PRINTS PR00813 Bacterial general secretion pathway protein G signature 48 66 2.2E-9 T 13-10-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 Astex_3722 224aad5247532fd4ce62862b86ca4096 142 TIGRFAM TIGR01710 typeII_sec_gspG: type II secretion system protein G 12 137 3.5E-33 T 13-10-2018 IPR010054 General secretion pathway protein G GO:0008565|GO:0015627|GO:0015628 Astex_3722 224aad5247532fd4ce62862b86ca4096 142 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 11 32 8.9E-6 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site Astex_3722 224aad5247532fd4ce62862b86ca4096 142 Pfam PF07963 Prokaryotic N-terminal methylation motif 10 32 4.2E-5 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site Astex_1834 ac875675042da812ecd726e4cd453b87 207 Pfam PF00293 NUDIX domain 58 170 5.4E-14 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 Astex_1834 ac875675042da812ecd726e4cd453b87 207 Gene3D G3DSA:3.90.79.10 23 195 9.0E-38 T 13-10-2018 Astex_1834 ac875675042da812ecd726e4cd453b87 207 SUPERFAMILY SSF55811 21 190 1.12E-34 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 Astex_1834 ac875675042da812ecd726e4cd453b87 207 ProSitePatterns PS00893 Nudix box signature. 93 114 - T 13-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 Astex_0689 8497eb6f76936ea1adf40e469016face 766 SUPERFAMILY SSF53756 33 400 3.14E-47 T 13-10-2018 Astex_0689 8497eb6f76936ea1adf40e469016face 766 Pfam PF00534 Glycosyl transferases group 1 209 385 4.2E-22 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 Astex_0689 8497eb6f76936ea1adf40e469016face 766 Pfam PF13439 Glycosyltransferase Family 4 82 197 6.9E-7 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 Astex_0689 8497eb6f76936ea1adf40e469016face 766 Gene3D G3DSA:3.40.50.2000 120 399 3.4E-42 T 13-10-2018 Astex_0689 8497eb6f76936ea1adf40e469016face 766 Gene3D G3DSA:3.40.50.2000 198 387 3.4E-42 T 13-10-2018 Astex_0689 8497eb6f76936ea1adf40e469016face 766 SUPERFAMILY SSF48208 603 746 3.74E-6 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 Astex_2836 2591f62d77c806298e89f321dca48249 310 Gene3D G3DSA:3.30.360.10 120 288 2.0E-28 T 13-10-2018 Astex_2836 2591f62d77c806298e89f321dca48249 310 SUPERFAMILY SSF55347 116 284 2.45E-31 T 13-10-2018 Astex_2836 2591f62d77c806298e89f321dca48249 310 SMART SM00859 4 105 1.3E-19 T 13-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 Astex_2836 2591f62d77c806298e89f321dca48249 310 TIGRFAM TIGR01851 argC_other: N-acetyl-gamma-glutamyl-phosphate reductase 3 303 1.4E-124 T 13-10-2018 IPR010136 N-acetyl-gamma-glutamyl-phosphate reductase, type 2 GO:0003942|GO:0005737|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Astex_2836 2591f62d77c806298e89f321dca48249 310 SUPERFAMILY SSF51735 1 136 8.76E-35 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_2836 2591f62d77c806298e89f321dca48249 310 Gene3D G3DSA:3.40.50.720 1 119 3.5E-20 T 13-10-2018 Astex_2836 2591f62d77c806298e89f321dca48249 310 Hamap MF_01110 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 1 303 51.324 T 13-10-2018 IPR010136 N-acetyl-gamma-glutamyl-phosphate reductase, type 2 GO:0003942|GO:0005737|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Astex_2836 2591f62d77c806298e89f321dca48249 310 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 6 101 9.2E-10 T 13-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 Astex_3170 446bd1ea1798e6a8ec154bc150a781f5 651 SUPERFAMILY SSF55874 532 632 2.62E-18 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_3170 446bd1ea1798e6a8ec154bc150a781f5 651 Pfam PF07730 Histidine kinase 443 476 1.6E-5 T 13-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Astex_3170 446bd1ea1798e6a8ec154bc150a781f5 651 SMART SM00387 539 635 1.7E-9 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_3170 446bd1ea1798e6a8ec154bc150a781f5 651 Gene3D G3DSA:3.30.565.10 506 635 2.9E-25 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_3170 446bd1ea1798e6a8ec154bc150a781f5 651 PRINTS PR00344 Bacterial sensor protein C-terminal signature 619 632 7.7E-7 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_3170 446bd1ea1798e6a8ec154bc150a781f5 651 PRINTS PR00344 Bacterial sensor protein C-terminal signature 595 613 7.7E-7 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_3170 446bd1ea1798e6a8ec154bc150a781f5 651 PRINTS PR00344 Bacterial sensor protein C-terminal signature 578 592 7.7E-7 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_3170 446bd1ea1798e6a8ec154bc150a781f5 651 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 543 633 2.9E-8 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_2424 06ef31c945c9368310be77b4f9e7eac5 346 SUPERFAMILY SSF51556 31 332 5.63E-44 T 13-10-2018 IPR032466 Metal-dependent hydrolase Astex_2424 06ef31c945c9368310be77b4f9e7eac5 346 Pfam PF04909 Amidohydrolase 33 331 8.5E-43 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 Astex_2424 06ef31c945c9368310be77b4f9e7eac5 346 Gene3D G3DSA:3.20.20.140 31 341 8.5E-48 T 13-10-2018 Astex_1364 bf824a0371f3b1f57405f35e9bf61913 295 Pfam PF03466 LysR substrate binding domain 90 260 7.3E-29 T 13-10-2018 IPR005119 LysR, substrate-binding Astex_1364 bf824a0371f3b1f57405f35e9bf61913 295 SUPERFAMILY SSF53850 90 248 3.1E-28 T 13-10-2018 Astex_1364 bf824a0371f3b1f57405f35e9bf61913 295 Gene3D G3DSA:3.40.190.10 97 260 6.2E-54 T 13-10-2018 Astex_1364 bf824a0371f3b1f57405f35e9bf61913 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 2.3E-8 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_1364 bf824a0371f3b1f57405f35e9bf61913 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 2.3E-8 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_1364 bf824a0371f3b1f57405f35e9bf61913 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 2.3E-8 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_1364 bf824a0371f3b1f57405f35e9bf61913 295 SUPERFAMILY SSF46785 6 113 9.91E-25 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_1364 bf824a0371f3b1f57405f35e9bf61913 295 Gene3D G3DSA:1.10.10.10 2 87 6.4E-26 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1364 bf824a0371f3b1f57405f35e9bf61913 295 Gene3D G3DSA:3.40.190.10 164 255 6.2E-54 T 13-10-2018 Astex_1364 bf824a0371f3b1f57405f35e9bf61913 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 5.9E-21 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_2648 3218dd8ed8edcf911039f8369cc1af7b 238 Hamap MF_01547 Ribosomal RNA large subunit methyltransferase E [rlmE]. 47 237 28.781 T 13-10-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 Astex_2648 3218dd8ed8edcf911039f8369cc1af7b 238 PIRSF PIRSF005461 28 238 2.8E-70 T 13-10-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 Astex_2648 3218dd8ed8edcf911039f8369cc1af7b 238 SUPERFAMILY SSF53335 36 238 1.19E-39 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Astex_2648 3218dd8ed8edcf911039f8369cc1af7b 238 Gene3D G3DSA:3.40.50.150 59 238 1.6E-59 T 13-10-2018 Astex_2648 3218dd8ed8edcf911039f8369cc1af7b 238 Pfam PF01728 FtsJ-like methyltransferase 63 236 1.4E-53 T 13-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 Astex_0203 ff7c215cf466f7a1ac863fe9c480cdd5 398 Pfam PF00155 Aminotransferase class I and II 30 382 1.6E-58 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Astex_0203 ff7c215cf466f7a1ac863fe9c480cdd5 398 SUPERFAMILY SSF53383 1 389 2.58E-106 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Astex_0203 ff7c215cf466f7a1ac863fe9c480cdd5 398 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 235 248 - T 13-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 Astex_0203 ff7c215cf466f7a1ac863fe9c480cdd5 398 Gene3D G3DSA:3.90.1150.10 288 385 8.1E-116 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Astex_0203 ff7c215cf466f7a1ac863fe9c480cdd5 398 Gene3D G3DSA:3.40.640.10 64 287 8.1E-116 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Astex_3057 4fb8bd081101b72ec8c0e23bd94dc051 270 Hamap MF_01974 Methionine aminopeptidase [map]. 14 261 38.289 T 13-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 Astex_3057 4fb8bd081101b72ec8c0e23bd94dc051 270 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 14 260 5.7E-87 T 13-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 Astex_3057 4fb8bd081101b72ec8c0e23bd94dc051 270 Pfam PF00557 Metallopeptidase family M24 23 252 2.3E-48 T 13-10-2018 IPR000994 Peptidase M24 Astex_3057 4fb8bd081101b72ec8c0e23bd94dc051 270 PRINTS PR00599 Methionine aminopeptidase-1 signature 102 118 1.2E-20 T 13-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 Astex_3057 4fb8bd081101b72ec8c0e23bd94dc051 270 PRINTS PR00599 Methionine aminopeptidase-1 signature 172 184 1.2E-20 T 13-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 Astex_3057 4fb8bd081101b72ec8c0e23bd94dc051 270 PRINTS PR00599 Methionine aminopeptidase-1 signature 203 215 1.2E-20 T 13-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 Astex_3057 4fb8bd081101b72ec8c0e23bd94dc051 270 PRINTS PR00599 Methionine aminopeptidase-1 signature 79 92 1.2E-20 T 13-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 Astex_3057 4fb8bd081101b72ec8c0e23bd94dc051 270 SUPERFAMILY SSF55920 16 262 3.4E-84 T 13-10-2018 IPR036005 Creatinase/aminopeptidase-like Astex_3057 4fb8bd081101b72ec8c0e23bd94dc051 270 Gene3D G3DSA:3.90.230.10 1 267 1.2E-99 T 13-10-2018 Astex_3057 4fb8bd081101b72ec8c0e23bd94dc051 270 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 178 196 - T 13-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 Astex_0280 9016f98e11be05353fb5845a9d32ce0a 306 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 138 1.3E-8 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Astex_0280 9016f98e11be05353fb5845a9d32ce0a 306 SUPERFAMILY SSF51905 5 298 7.99E-32 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_0280 9016f98e11be05353fb5845a9d32ce0a 306 Gene3D G3DSA:3.50.50.60 7 295 6.4E-91 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_0280 9016f98e11be05353fb5845a9d32ce0a 306 Gene3D G3DSA:3.50.50.60 119 229 6.4E-91 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_0280 9016f98e11be05353fb5845a9d32ce0a 306 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 128 140 4.0E-13 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Astex_0280 9016f98e11be05353fb5845a9d32ce0a 306 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 4.0E-13 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Astex_0280 9016f98e11be05353fb5845a9d32ce0a 306 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 106 114 4.0E-13 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Astex_0280 9016f98e11be05353fb5845a9d32ce0a 306 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 263 281 4.0E-13 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Astex_0280 9016f98e11be05353fb5845a9d32ce0a 306 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 185 287 8.8E-10 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Astex_0280 9016f98e11be05353fb5845a9d32ce0a 306 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 105 123 6.7E-13 T 13-10-2018 Astex_0280 9016f98e11be05353fb5845a9d32ce0a 306 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 275 6.7E-13 T 13-10-2018 Astex_0280 9016f98e11be05353fb5845a9d32ce0a 306 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 6.7E-13 T 13-10-2018 Astex_1734 bb07aa7001cdfe358c304c6576e8b4bf 363 SUPERFAMILY SSF51395 1 347 4.89E-94 T 13-10-2018 Astex_1734 bb07aa7001cdfe358c304c6576e8b4bf 363 Gene3D G3DSA:3.20.20.70 3 358 8.4E-102 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_1734 bb07aa7001cdfe358c304c6576e8b4bf 363 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 6 346 1.0E-61 T 13-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 Astex_1087 505cdb06429b583d7270dabb6b545950 325 SUPERFAMILY SSF46689 271 306 6.72E-8 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Astex_1087 505cdb06429b583d7270dabb6b545950 325 Gene3D G3DSA:1.10.10.60 199 315 1.9E-21 T 13-10-2018 Astex_1087 505cdb06429b583d7270dabb6b545950 325 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 273 288 6.1E-6 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 Astex_1087 505cdb06429b583d7270dabb6b545950 325 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 288 304 6.1E-6 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 Astex_1087 505cdb06429b583d7270dabb6b545950 325 Pfam PF12833 Helix-turn-helix domain 227 305 1.6E-13 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Astex_1087 505cdb06429b583d7270dabb6b545950 325 SMART SM00342 221 304 1.2E-12 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Astex_2987 25c8134801477ef8cce182e42bd7709f 394 Pfam PF03486 HI0933-like protein 5 392 1.4E-135 T 13-10-2018 Astex_2987 25c8134801477ef8cce182e42bd7709f 394 SUPERFAMILY SSF160996 190 340 1.06E-37 T 13-10-2018 Astex_2987 25c8134801477ef8cce182e42bd7709f 394 Gene3D G3DSA:1.10.8.260 261 322 2.3E-121 T 13-10-2018 IPR023166 HI0933-like insert domain superfamily Astex_2987 25c8134801477ef8cce182e42bd7709f 394 Gene3D G3DSA:3.50.50.60 7 391 2.3E-121 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_2987 25c8134801477ef8cce182e42bd7709f 394 SUPERFAMILY SSF51905 1 394 6.1E-56 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_2987 25c8134801477ef8cce182e42bd7709f 394 Gene3D G3DSA:2.40.30.10 188 339 2.3E-121 T 13-10-2018 Astex_2987 25c8134801477ef8cce182e42bd7709f 394 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 3.9E-6 T 13-10-2018 Astex_2987 25c8134801477ef8cce182e42bd7709f 394 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 155 164 3.9E-6 T 13-10-2018 Astex_2987 25c8134801477ef8cce182e42bd7709f 394 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 7 392 1.7E-121 T 13-10-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like Astex_1936 79ead02876e06a61685e78574931c352 422 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 16 412 1.7E-90 T 13-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 Astex_1936 79ead02876e06a61685e78574931c352 422 Gene3D G3DSA:3.65.10.10 20 410 4.1E-109 T 13-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 Astex_1936 79ead02876e06a61685e78574931c352 422 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 20 416 2.4E-99 T 13-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 Astex_1936 79ead02876e06a61685e78574931c352 422 ProSitePatterns PS00104 EPSP synthase signature 1. 93 107 - T 13-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 Astex_1936 79ead02876e06a61685e78574931c352 422 Gene3D G3DSA:3.65.10.10 28 242 4.1E-109 T 13-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 Astex_1936 79ead02876e06a61685e78574931c352 422 SUPERFAMILY SSF55205 15 418 1.57E-93 T 13-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 Astex_1936 79ead02876e06a61685e78574931c352 422 PIRSF PIRSF000505 7 421 2.0E-117 T 13-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 Astex_1936 79ead02876e06a61685e78574931c352 422 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 16 418 27.076 T 13-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 Astex_2576 5ffe1a94f1c1c8d1a185f4e99fe44df9 211 TIGRFAM TIGR02466 TIGR02466: conserved hypothetical protein 12 211 1.7E-68 T 13-10-2018 IPR012668 Conserved hypothetical protein CHP02466 Astex_2576 5ffe1a94f1c1c8d1a185f4e99fe44df9 211 SUPERFAMILY SSF51197 145 209 6.73E-5 T 13-10-2018 Astex_2576 5ffe1a94f1c1c8d1a185f4e99fe44df9 211 Gene3D G3DSA:2.60.120.620 17 211 1.5E-62 T 13-10-2018 Astex_2576 5ffe1a94f1c1c8d1a185f4e99fe44df9 211 Pfam PF13759 Putative 2OG-Fe(II) oxygenase 108 208 1.6E-33 T 13-10-2018 IPR012668 Conserved hypothetical protein CHP02466 Astex_2724 c94f94ca8743d10a71ef8b1ff76f4490 869 Gene3D G3DSA:2.60.40.10 747 852 7.5E-25 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_2724 c94f94ca8743d10a71ef8b1ff76f4490 869 SUPERFAMILY SSF56988 453 622 9.02E-26 T 13-10-2018 Astex_2724 c94f94ca8743d10a71ef8b1ff76f4490 869 Gene3D G3DSA:3.20.20.300 34 347 4.8E-90 T 13-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 Astex_2724 c94f94ca8743d10a71ef8b1ff76f4490 869 SMART SM00758 451 595 3.2E-10 T 13-10-2018 IPR011658 PA14 domain Astex_2724 c94f94ca8743d10a71ef8b1ff76f4490 869 SMART SM01217 781 848 8.5E-17 T 13-10-2018 IPR026891 Fibronectin type III-like domain Astex_2724 c94f94ca8743d10a71ef8b1ff76f4490 869 Gene3D G3DSA:3.40.50.1700 353 478 1.0E-17 T 13-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 Astex_2724 c94f94ca8743d10a71ef8b1ff76f4490 869 SUPERFAMILY SSF51445 32 367 3.79E-85 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_2724 c94f94ca8743d10a71ef8b1ff76f4490 869 Pfam PF07691 PA14 domain 453 590 1.0E-16 T 13-10-2018 IPR011658 PA14 domain Astex_2724 c94f94ca8743d10a71ef8b1ff76f4490 869 PRINTS PR00133 Glycosyl hydrolase family 3 signature 252 270 2.6E-11 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_2724 c94f94ca8743d10a71ef8b1ff76f4490 869 PRINTS PR00133 Glycosyl hydrolase family 3 signature 86 105 2.6E-11 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_2724 c94f94ca8743d10a71ef8b1ff76f4490 869 PRINTS PR00133 Glycosyl hydrolase family 3 signature 181 197 2.6E-11 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_2724 c94f94ca8743d10a71ef8b1ff76f4490 869 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 71 329 1.9E-47 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_2724 c94f94ca8743d10a71ef8b1ff76f4490 869 SUPERFAMILY SSF52279 368 747 2.09E-54 T 13-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 Astex_2724 c94f94ca8743d10a71ef8b1ff76f4490 869 Gene3D G3DSA:3.40.50.1700 537 746 4.4E-60 T 13-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 Astex_2724 c94f94ca8743d10a71ef8b1ff76f4490 869 Pfam PF14310 Fibronectin type III-like domain 781 846 5.6E-14 T 13-10-2018 IPR026891 Fibronectin type III-like domain Astex_2724 c94f94ca8743d10a71ef8b1ff76f4490 869 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 368 744 7.5E-63 T 13-10-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 Astex_1901 8b2abe397078d3fb34317bcc2c660029 259 SUPERFAMILY SSF46785 21 88 1.72E-13 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_1901 8b2abe397078d3fb34317bcc2c660029 259 SUPERFAMILY SSF55781 84 258 1.11E-27 T 13-10-2018 Astex_1901 8b2abe397078d3fb34317bcc2c660029 259 Gene3D G3DSA:1.10.10.10 12 89 9.8E-17 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1901 8b2abe397078d3fb34317bcc2c660029 259 SMART SM00346 19 109 4.8E-17 T 13-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Astex_1901 8b2abe397078d3fb34317bcc2c660029 259 Pfam PF09339 IclR helix-turn-helix domain 21 71 2.7E-13 T 13-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Astex_1901 8b2abe397078d3fb34317bcc2c660029 259 Gene3D G3DSA:3.30.450.40 93 256 3.9E-25 T 13-10-2018 IPR029016 GAF-like domain superfamily Astex_2920 861ca29e8ac2ff67de47a7dcd6b28dec 447 SUPERFAMILY SSF51230 2 93 9.29E-27 T 13-10-2018 IPR011053 Single hybrid motif Astex_2920 861ca29e8ac2ff67de47a7dcd6b28dec 447 Pfam PF02780 Transketolase, C-terminal domain 315 437 1.6E-43 T 13-10-2018 IPR033248 Transketolase, C-terminal domain Astex_2920 861ca29e8ac2ff67de47a7dcd6b28dec 447 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 26 55 - T 13-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 Astex_2920 861ca29e8ac2ff67de47a7dcd6b28dec 447 SMART SM00861 125 300 1.3E-55 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain Astex_2920 861ca29e8ac2ff67de47a7dcd6b28dec 447 Pfam PF02779 Transketolase, pyrimidine binding domain 124 299 2.7E-47 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain Astex_2920 861ca29e8ac2ff67de47a7dcd6b28dec 447 SUPERFAMILY SSF52922 309 444 5.76E-44 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Astex_2920 861ca29e8ac2ff67de47a7dcd6b28dec 447 Gene3D G3DSA:2.40.50.100 1 102 6.8E-30 T 13-10-2018 Astex_2920 861ca29e8ac2ff67de47a7dcd6b28dec 447 Pfam PF00364 Biotin-requiring enzyme 3 76 1.3E-21 T 13-10-2018 IPR000089 Biotin/lipoyl attachment Astex_2920 861ca29e8ac2ff67de47a7dcd6b28dec 447 SUPERFAMILY SSF52518 124 314 1.42E-64 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold Astex_2920 861ca29e8ac2ff67de47a7dcd6b28dec 447 Gene3D G3DSA:3.40.50.920 312 446 9.7E-50 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Astex_2920 861ca29e8ac2ff67de47a7dcd6b28dec 447 Gene3D G3DSA:3.40.50.970 124 311 2.5E-81 T 13-10-2018 Astex_0499 ea6810404d0b68c19ed08f3ea51c3cd5 292 PIRSF PIRSF000105 1 292 1.6E-84 T 13-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 Astex_0499 ea6810404d0b68c19ed08f3ea51c3cd5 292 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 7 184 1.8E-61 T 13-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 Astex_0499 ea6810404d0b68c19ed08f3ea51c3cd5 292 SUPERFAMILY SSF48179 186 288 3.83E-35 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Astex_0499 ea6810404d0b68c19ed08f3ea51c3cd5 292 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 188 283 2.7E-34 T 13-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 Astex_0499 ea6810404d0b68c19ed08f3ea51c3cd5 292 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 184 209 - T 13-10-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 Astex_0499 ea6810404d0b68c19ed08f3ea51c3cd5 292 Gene3D G3DSA:1.10.1040.50 191 292 6.4E-35 T 13-10-2018 Astex_0499 ea6810404d0b68c19ed08f3ea51c3cd5 292 SUPERFAMILY SSF51735 1 186 7.98E-57 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_0499 ea6810404d0b68c19ed08f3ea51c3cd5 292 Gene3D G3DSA:3.40.50.720 2 190 2.8E-66 T 13-10-2018 Astex_2844 f81e660bb0ce028c39f96be402ea5d04 300 ProSitePatterns PS01126 Elongation factor Ts signature 1. 12 27 - T 13-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 Astex_2844 f81e660bb0ce028c39f96be402ea5d04 300 Gene3D G3DSA:3.30.479.20 141 279 3.6E-41 T 13-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 Astex_2844 f81e660bb0ce028c39f96be402ea5d04 300 Gene3D G3DSA:1.10.8.10 1 56 9.5E-26 T 13-10-2018 Astex_2844 f81e660bb0ce028c39f96be402ea5d04 300 SUPERFAMILY SSF54713 141 299 7.59E-45 T 13-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 Astex_2844 f81e660bb0ce028c39f96be402ea5d04 300 Hamap MF_00050 Elongation factor Ts [tsf]. 1 297 70.894 T 13-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 Astex_2844 f81e660bb0ce028c39f96be402ea5d04 300 Gene3D G3DSA:3.30.479.20 57 139 1.3E-20 T 13-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 Astex_2844 f81e660bb0ce028c39f96be402ea5d04 300 Pfam PF00889 Elongation factor TS 71 280 4.5E-61 T 13-10-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0006414 Reactome: R-HSA-5389840 Astex_2844 f81e660bb0ce028c39f96be402ea5d04 300 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 298 4.6E-86 T 13-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 Astex_2844 f81e660bb0ce028c39f96be402ea5d04 300 SUPERFAMILY SSF54713 56 135 2.18E-15 T 13-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 Astex_2844 f81e660bb0ce028c39f96be402ea5d04 300 Gene3D G3DSA:1.10.286.20 194 238 3.6E-41 T 13-10-2018 Astex_2844 f81e660bb0ce028c39f96be402ea5d04 300 SUPERFAMILY SSF46934 4 55 5.79E-18 T 13-10-2018 IPR009060 UBA-like superfamily GO:0005515 Astex_2844 f81e660bb0ce028c39f96be402ea5d04 300 ProSitePatterns PS01127 Elongation factor Ts signature 2. 75 85 - T 13-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 Astex_2147 45401fa169f1d03882201e1afa5fbe23 370 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 171 360 3.8E-25 T 13-10-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0044237|GO:0051537|GO:0055114 Astex_2147 45401fa169f1d03882201e1afa5fbe23 370 SUPERFAMILY SSF55961 146 368 1.73E-31 T 13-10-2018 Astex_2147 45401fa169f1d03882201e1afa5fbe23 370 SUPERFAMILY SSF50022 8 144 4.58E-34 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 Astex_2147 45401fa169f1d03882201e1afa5fbe23 370 Gene3D G3DSA:3.90.380.10 236 367 1.6E-8 T 13-10-2018 Astex_2147 45401fa169f1d03882201e1afa5fbe23 370 Gene3D G3DSA:3.90.380.10 9 204 3.4E-41 T 13-10-2018 Astex_2147 45401fa169f1d03882201e1afa5fbe23 370 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 16 41 5.4E-13 T 13-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 Astex_2147 45401fa169f1d03882201e1afa5fbe23 370 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 130 156 5.4E-13 T 13-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 Astex_2147 45401fa169f1d03882201e1afa5fbe23 370 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 46 61 5.4E-13 T 13-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 Astex_2147 45401fa169f1d03882201e1afa5fbe23 370 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 86 106 5.4E-13 T 13-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 Astex_2147 45401fa169f1d03882201e1afa5fbe23 370 Gene3D G3DSA:2.102.10.10 29 155 3.4E-41 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 Astex_2147 45401fa169f1d03882201e1afa5fbe23 370 Pfam PF00355 Rieske [2Fe-2S] domain 31 114 1.2E-16 T 13-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Astex_0592 19dcd772c5aa51519a6e1fd48cba5664 561 Pfam PF08345 Flagellar M-ring protein C-terminal 242 412 3.1E-37 T 13-10-2018 IPR013556 Flagellar M-ring C-terminal Astex_0592 19dcd772c5aa51519a6e1fd48cba5664 561 Pfam PF01514 Secretory protein of YscJ/FliF family 21 208 5.3E-63 T 13-10-2018 IPR006182 Secretory protein YscJ/FliF Astex_0592 19dcd772c5aa51519a6e1fd48cba5664 561 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 11 462 1.6E-76 T 13-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 Astex_0592 19dcd772c5aa51519a6e1fd48cba5664 561 PRINTS PR01009 Flagellar M-ring protein signature 142 156 3.8E-33 T 13-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 Astex_0592 19dcd772c5aa51519a6e1fd48cba5664 561 PRINTS PR01009 Flagellar M-ring protein signature 253 271 3.8E-33 T 13-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 Astex_0592 19dcd772c5aa51519a6e1fd48cba5664 561 PRINTS PR01009 Flagellar M-ring protein signature 110 128 3.8E-33 T 13-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 Astex_0592 19dcd772c5aa51519a6e1fd48cba5664 561 PRINTS PR01009 Flagellar M-ring protein signature 184 202 3.8E-33 T 13-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 Astex_0592 19dcd772c5aa51519a6e1fd48cba5664 561 PRINTS PR01009 Flagellar M-ring protein signature 327 351 3.8E-33 T 13-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 Astex_0592 19dcd772c5aa51519a6e1fd48cba5664 561 PIRSF PIRSF004862 1 561 1.0E-122 T 13-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 Astex_0592 19dcd772c5aa51519a6e1fd48cba5664 561 Gene3D G3DSA:3.30.300.30 118 210 6.7E-11 T 13-10-2018 Astex_0016 10e495e86f0933246338887ab424c563 464 Pfam PF01189 16S rRNA methyltransferase RsmB/F 268 460 8.4E-52 T 13-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 Astex_0016 10e495e86f0933246338887ab424c563 464 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 444 461 9.4E-22 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase Astex_0016 10e495e86f0933246338887ab424c563 464 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 276 286 9.4E-22 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase Astex_0016 10e495e86f0933246338887ab424c563 464 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 387 403 9.4E-22 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase Astex_0016 10e495e86f0933246338887ab424c563 464 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 247 261 9.4E-22 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase Astex_0016 10e495e86f0933246338887ab424c563 464 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 337 349 9.4E-22 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase Astex_0016 10e495e86f0933246338887ab424c563 464 SUPERFAMILY SSF53335 177 461 5.31E-58 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Astex_0016 10e495e86f0933246338887ab424c563 464 SUPERFAMILY SSF48013 45 181 3.43E-20 T 13-10-2018 IPR035926 NusB-like superfamily Astex_0016 10e495e86f0933246338887ab424c563 464 Pfam PF01029 NusB family 45 164 4.4E-16 T 13-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 Astex_0016 10e495e86f0933246338887ab424c563 464 Gene3D G3DSA:1.10.940.10 43 175 5.5E-26 T 13-10-2018 IPR035926 NusB-like superfamily Astex_0016 10e495e86f0933246338887ab424c563 464 Gene3D G3DSA:3.40.50.150 176 461 7.1E-63 T 13-10-2018 Astex_2862 a3071a3231becfeb80c739ad0f3fd987 235 Gene3D G3DSA:2.10.109.10 116 234 9.0E-37 T 13-10-2018 Astex_2862 a3071a3231becfeb80c739ad0f3fd987 235 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 158 169 2.8E-8 T 13-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 Astex_2862 a3071a3231becfeb80c739ad0f3fd987 235 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 147 157 2.8E-8 T 13-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 Astex_2862 a3071a3231becfeb80c739ad0f3fd987 235 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 187 199 2.8E-8 T 13-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 Astex_2862 a3071a3231becfeb80c739ad0f3fd987 235 Hamap MF_00015 LexA repressor [lexA]. 1 234 33.617 T 13-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 Astex_2862 a3071a3231becfeb80c739ad0f3fd987 235 SUPERFAMILY SSF51306 111 232 1.29E-31 T 13-10-2018 IPR036286 LexA/Signal peptidase-like superfamily Astex_2862 a3071a3231becfeb80c739ad0f3fd987 235 SUPERFAMILY SSF46785 2 68 6.06E-18 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_2862 a3071a3231becfeb80c739ad0f3fd987 235 Gene3D G3DSA:1.10.10.10 1 68 2.1E-17 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_2862 a3071a3231becfeb80c739ad0f3fd987 235 Pfam PF01726 LexA DNA binding domain 2 63 4.7E-15 T 13-10-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 Astex_2862 a3071a3231becfeb80c739ad0f3fd987 235 Pfam PF00717 Peptidase S24-like 150 217 7.5E-15 T 13-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C Astex_2862 a3071a3231becfeb80c739ad0f3fd987 235 TIGRFAM TIGR00498 lexA: repressor LexA 2 234 7.7E-53 T 13-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 Astex_3242 5a644b64852b8add5664cda73b6f2030 499 PIRSF PIRSF001549 16 477 3.3E-108 T 13-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 Astex_3242 5a644b64852b8add5664cda73b6f2030 499 Pfam PF03129 Anticodon binding domain 389 464 4.8E-8 T 13-10-2018 IPR004154 Anticodon-binding Astex_3242 5a644b64852b8add5664cda73b6f2030 499 Pfam PF13393 Histidyl-tRNA synthetase 23 370 1.8E-43 T 13-10-2018 Astex_3242 5a644b64852b8add5664cda73b6f2030 499 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 16 495 24.83 T 13-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 Astex_3242 5a644b64852b8add5664cda73b6f2030 499 Gene3D G3DSA:3.30.930.10 12 379 5.7E-92 T 13-10-2018 Astex_3242 5a644b64852b8add5664cda73b6f2030 499 SUPERFAMILY SSF55681 19 374 3.58E-63 T 13-10-2018 Astex_3242 5a644b64852b8add5664cda73b6f2030 499 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 20 462 4.2E-107 T 13-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 Astex_3242 5a644b64852b8add5664cda73b6f2030 499 Gene3D G3DSA:3.40.50.800 387 474 2.2E-19 T 13-10-2018 IPR036621 Anticodon-binding domain superfamily Astex_3242 5a644b64852b8add5664cda73b6f2030 499 SUPERFAMILY SSF52954 389 495 8.61E-17 T 13-10-2018 Astex_3668 a2a97a5006afa464ed894e5819046433 312 SUPERFAMILY SSF51569 16 302 6.7E-68 T 13-10-2018 Astex_3668 a2a97a5006afa464ed894e5819046433 312 TIGRFAM TIGR03249 KdgD: 5-dehydro-4-deoxyglucarate dehydratase 6 303 6.5E-129 T 13-10-2018 IPR017655 5-dehydro-4-deoxyglucarate dehydratase GO:0016052|GO:0047448 KEGG: 00053+4.2.1.41|MetaCyc: PWY-6486|MetaCyc: PWY-6497|MetaCyc: PWY-6499|MetaCyc: PWY-6501 Astex_3668 a2a97a5006afa464ed894e5819046433 312 Gene3D G3DSA:3.20.20.70 4 311 3.1E-98 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_3668 a2a97a5006afa464ed894e5819046433 312 Hamap MF_00694 Probable 5-dehydro-4-deoxyglucarate dehydratase. 13 304 43.029 T 13-10-2018 IPR017655 5-dehydro-4-deoxyglucarate dehydratase GO:0016052|GO:0047448 KEGG: 00053+4.2.1.41|MetaCyc: PWY-6486|MetaCyc: PWY-6497|MetaCyc: PWY-6499|MetaCyc: PWY-6501 Astex_3668 a2a97a5006afa464ed894e5819046433 312 PIRSF PIRSF001365 9 310 2.7E-58 T 13-10-2018 IPR002220 DapA-like GO:0016829 Astex_3668 a2a97a5006afa464ed894e5819046433 312 SMART SM01130 13 304 7.2E-70 T 13-10-2018 IPR002220 DapA-like GO:0016829 Astex_3668 a2a97a5006afa464ed894e5819046433 312 Pfam PF00701 Dihydrodipicolinate synthetase family 16 301 8.2E-56 T 13-10-2018 IPR002220 DapA-like GO:0016829 Astex_0074 fbc20dc878b82f62722b6473118e4789 304 SMART SM00748 172 292 1.4E-5 T 13-10-2018 IPR007842 HEPN domain Astex_0074 fbc20dc878b82f62722b6473118e4789 304 Gene3D G3DSA:1.20.120.330 155 303 2.8E-47 T 13-10-2018 Astex_0074 fbc20dc878b82f62722b6473118e4789 304 Pfam PF05168 HEPN domain 168 276 7.3E-10 T 13-10-2018 IPR007842 HEPN domain Astex_0074 fbc20dc878b82f62722b6473118e4789 304 Pfam PF01909 Nucleotidyltransferase domain 37 88 2.3E-4 T 13-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 Astex_0074 fbc20dc878b82f62722b6473118e4789 304 SUPERFAMILY SSF81301 30 146 4.5E-11 T 13-10-2018 Astex_0074 fbc20dc878b82f62722b6473118e4789 304 Gene3D G3DSA:3.30.460.10 29 141 8.3E-13 T 13-10-2018 Astex_0074 fbc20dc878b82f62722b6473118e4789 304 SUPERFAMILY SSF81593 170 289 2.98E-9 T 13-10-2018 Astex_1542 52ee37f8203ceec361f0a898379c6a73 100 Gene3D G3DSA:1.10.10.10 6 98 2.8E-24 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1542 52ee37f8203ceec361f0a898379c6a73 100 Pfam PF13601 Winged helix DNA-binding domain 17 95 4.0E-30 T 13-10-2018 IPR027395 Winged helix DNA-binding domain Astex_1542 52ee37f8203ceec361f0a898379c6a73 100 SUPERFAMILY SSF46785 11 96 4.43E-16 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_3620 0e5e68c4f84942d75c06c28132cb5146 788 Gene3D G3DSA:1.50.10.10 47 744 1.4E-208 T 13-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 Astex_3620 0e5e68c4f84942d75c06c28132cb5146 788 PIRSF PIRSF007663 14 782 3.7E-231 T 13-10-2018 IPR016518 Alpha-L-fucosidase GO:0004560 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807 Astex_3620 0e5e68c4f84942d75c06c28132cb5146 788 Gene3D G3DSA:2.60.40.1180 307 751 1.4E-208 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta Astex_3620 0e5e68c4f84942d75c06c28132cb5146 788 Gene3D G3DSA:2.70.98.50 51 306 1.4E-208 T 13-10-2018 Astex_3620 0e5e68c4f84942d75c06c28132cb5146 788 Pfam PF14498 Glycosyl hydrolase family 65, N-terminal domain 38 267 8.3E-69 T 13-10-2018 IPR027414 Glycosyl hydrolase family 95, N-terminal domain KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807 Astex_3620 0e5e68c4f84942d75c06c28132cb5146 788 SUPERFAMILY SSF48208 272 745 1.19E-89 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 Astex_0092 902e033673ab8c9a2dbead39ea9c7f1f 612 Gene3D G3DSA:3.60.20.10 2 240 1.1E-73 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Astex_0092 902e033673ab8c9a2dbead39ea9c7f1f 612 SUPERFAMILY SSF53697 244 612 5.57E-107 T 13-10-2018 Astex_0092 902e033673ab8c9a2dbead39ea9c7f1f 612 SUPERFAMILY SSF56235 2 234 8.41E-72 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Astex_0092 902e033673ab8c9a2dbead39ea9c7f1f 612 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 612 1.1E-239 T 13-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 Astex_0092 902e033673ab8c9a2dbead39ea9c7f1f 612 Gene3D G3DSA:3.40.50.10490 248 611 1.8E-135 T 13-10-2018 Astex_0092 902e033673ab8c9a2dbead39ea9c7f1f 612 Pfam PF13522 Glutamine amidotransferase domain 64 191 3.7E-23 T 13-10-2018 Astex_0092 902e033673ab8c9a2dbead39ea9c7f1f 612 Pfam PF01380 SIS domain 459 594 9.5E-28 T 13-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 Astex_0092 902e033673ab8c9a2dbead39ea9c7f1f 612 Pfam PF01380 SIS domain 292 415 3.7E-26 T 13-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 Astex_0092 902e033673ab8c9a2dbead39ea9c7f1f 612 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 612 39.254 T 13-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 Astex_0092 902e033673ab8c9a2dbead39ea9c7f1f 612 Gene3D G3DSA:3.40.50.10490 445 597 1.8E-135 T 13-10-2018 Astex_0489 4ef3f280748e39cfec6227c6c4031784 349 Pfam PF09898 Uncharacterized protein conserved in bacteria (DUF2125) 37 346 1.8E-53 T 13-10-2018 IPR018666 Protein of unknown function DUF2125 Astex_0625 7a9bcf5cc3975e297c6268f123e4fa43 598 SUPERFAMILY SSF47384 305 387 1.18E-21 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Astex_0625 7a9bcf5cc3975e297c6268f123e4fa43 598 SMART SM00388 319 387 3.1E-18 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_0625 7a9bcf5cc3975e297c6268f123e4fa43 598 SUPERFAMILY SSF55874 376 548 1.96E-40 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_0625 7a9bcf5cc3975e297c6268f123e4fa43 598 Pfam PF00512 His Kinase A (phospho-acceptor) domain 320 386 5.0E-18 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_0625 7a9bcf5cc3975e297c6268f123e4fa43 598 SMART SM00387 433 545 1.0E-30 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_0625 7a9bcf5cc3975e297c6268f123e4fa43 598 Gene3D G3DSA:1.10.287.130 294 382 2.9E-25 T 13-10-2018 Astex_0625 7a9bcf5cc3975e297c6268f123e4fa43 598 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 434 542 1.9E-21 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_0625 7a9bcf5cc3975e297c6268f123e4fa43 598 Gene3D G3DSA:3.30.565.10 383 544 2.1E-38 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_0625 7a9bcf5cc3975e297c6268f123e4fa43 598 PRINTS PR00344 Bacterial sensor protein C-terminal signature 529 542 2.0E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_0625 7a9bcf5cc3975e297c6268f123e4fa43 598 PRINTS PR00344 Bacterial sensor protein C-terminal signature 471 485 2.0E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_0625 7a9bcf5cc3975e297c6268f123e4fa43 598 PRINTS PR00344 Bacterial sensor protein C-terminal signature 505 523 2.0E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1384 7ba1ec8f77904add6078c06537fb2f88 308 SUPERFAMILY SSF52266 53 301 2.66E-41 T 13-10-2018 Astex_1384 7ba1ec8f77904add6078c06537fb2f88 308 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 58 205 5.2E-12 T 13-10-2018 IPR013830 SGNH hydrolase-type esterase domain Astex_1589 2b8a55c668ea5bda5a2f4d663f3afb06 214 Gene3D G3DSA:3.40.50.150 30 209 2.0E-22 T 13-10-2018 Astex_1589 2b8a55c668ea5bda5a2f4d663f3afb06 214 SUPERFAMILY SSF53335 47 181 5.02E-23 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Astex_1589 2b8a55c668ea5bda5a2f4d663f3afb06 214 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 72 144 9.8E-12 T 13-10-2018 Astex_2420 7b6a70ca1b3885eb0526456d83cc9ba2 174 SUPERFAMILY SSF46785 11 168 3.22E-16 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_2420 7b6a70ca1b3885eb0526456d83cc9ba2 174 Gene3D G3DSA:1.10.10.10 6 99 8.5E-10 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_2420 7b6a70ca1b3885eb0526456d83cc9ba2 174 Pfam PF03551 Transcriptional regulator PadR-like family 33 87 4.8E-5 T 13-10-2018 IPR005149 Transcription regulator PadR, N-terminal Astex_3833 d46db13415fd0d155cad09c59fb33400 107 Pfam PF11604 Copper binding periplasmic protein CusF 40 105 1.2E-24 T 13-10-2018 IPR021647 Copper binding periplasmic protein CusF Astex_3833 d46db13415fd0d155cad09c59fb33400 107 Gene3D G3DSA:2.40.50.320 34 106 7.2E-26 T 13-10-2018 Astex_0957 bf495fd767f152e9c37f0ef1192b00dc 185 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 7 185 42.145 T 13-10-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_0957 bf495fd767f152e9c37f0ef1192b00dc 185 Pfam PF00281 Ribosomal protein L5 30 86 6.9E-27 T 13-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0957 bf495fd767f152e9c37f0ef1192b00dc 185 Gene3D G3DSA:3.30.1440.10 5 184 2.9E-80 T 13-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0957 bf495fd767f152e9c37f0ef1192b00dc 185 ProSitePatterns PS00358 Ribosomal protein L5 signature. 63 79 - T 13-10-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0957 bf495fd767f152e9c37f0ef1192b00dc 185 Pfam PF00673 ribosomal L5P family C-terminus 91 183 9.9E-41 T 13-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0957 bf495fd767f152e9c37f0ef1192b00dc 185 SUPERFAMILY SSF55282 9 184 1.06E-76 T 13-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0957 bf495fd767f152e9c37f0ef1192b00dc 185 PIRSF PIRSF002161 3 185 5.7E-65 T 13-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_2131 6b0631b53368bd56eba1992c13fe2c66 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 248 9.8E-58 T 13-10-2018 Astex_2131 6b0631b53368bd56eba1992c13fe2c66 251 TIGRFAM TIGR01832 kduD: 2-deoxy-D-gluconate 3-dehydrogenase 5 251 1.1E-122 T 13-10-2018 IPR011286 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase GO:0008678|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.127|MetaCyc: PWY-6507|MetaCyc: PWY-7562 Astex_2131 6b0631b53368bd56eba1992c13fe2c66 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.1E-41 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2131 6b0631b53368bd56eba1992c13fe2c66 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.1E-41 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2131 6b0631b53368bd56eba1992c13fe2c66 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 1.1E-41 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2131 6b0631b53368bd56eba1992c13fe2c66 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.1E-41 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2131 6b0631b53368bd56eba1992c13fe2c66 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.1E-41 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2131 6b0631b53368bd56eba1992c13fe2c66 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.1E-41 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2131 6b0631b53368bd56eba1992c13fe2c66 251 Gene3D G3DSA:3.40.50.720 2 251 7.1E-78 T 13-10-2018 Astex_2131 6b0631b53368bd56eba1992c13fe2c66 251 SUPERFAMILY SSF51735 4 250 1.14E-76 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_2131 6b0631b53368bd56eba1992c13fe2c66 251 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Astex_2131 6b0631b53368bd56eba1992c13fe2c66 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 3.7E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2131 6b0631b53368bd56eba1992c13fe2c66 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 3.7E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2131 6b0631b53368bd56eba1992c13fe2c66 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 3.7E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0166 ba7b6ebd53c469be37d7dd66a54ed7d6 470 Gene3D G3DSA:3.80.30.20 172 406 8.0E-87 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe Astex_0166 ba7b6ebd53c469be37d7dd66a54ed7d6 470 Pfam PF00919 Uncharacterized protein family UPF0004 26 130 2.2E-30 T 13-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 Astex_0166 ba7b6ebd53c469be37d7dd66a54ed7d6 470 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 178 198 - T 13-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 Astex_0166 ba7b6ebd53c469be37d7dd66a54ed7d6 470 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 26 463 1.8E-148 T 13-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 Astex_0166 ba7b6ebd53c469be37d7dd66a54ed7d6 470 Pfam PF04055 Radical SAM superfamily 179 352 4.2E-32 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Astex_0166 ba7b6ebd53c469be37d7dd66a54ed7d6 470 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 25 466 71.836 T 13-10-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 Astex_0166 ba7b6ebd53c469be37d7dd66a54ed7d6 470 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 26 465 3.9E-155 T 13-10-2018 Astex_0166 ba7b6ebd53c469be37d7dd66a54ed7d6 470 Pfam PF01938 TRAM domain 406 465 1.4E-6 T 13-10-2018 IPR002792 TRAM domain Astex_0166 ba7b6ebd53c469be37d7dd66a54ed7d6 470 SMART SM00729 174 394 9.8E-60 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Astex_0166 ba7b6ebd53c469be37d7dd66a54ed7d6 470 Gene3D G3DSA:3.40.50.12160 25 163 2.3E-35 T 13-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily Astex_0166 ba7b6ebd53c469be37d7dd66a54ed7d6 470 SUPERFAMILY SSF102114 151 398 3.27E-59 T 13-10-2018 Astex_0804 743d221bc6b7960afb3ae5ae0c602c47 141 Gene3D G3DSA:3.10.580.10 1 124 5.5E-33 T 13-10-2018 Astex_0804 743d221bc6b7960afb3ae5ae0c602c47 141 SMART SM00116 74 122 2.9E-5 T 13-10-2018 IPR000644 CBS domain Astex_0804 743d221bc6b7960afb3ae5ae0c602c47 141 SMART SM00116 10 57 2.4E-5 T 13-10-2018 IPR000644 CBS domain Astex_0804 743d221bc6b7960afb3ae5ae0c602c47 141 SUPERFAMILY SSF54631 1 122 9.22E-30 T 13-10-2018 Astex_0804 743d221bc6b7960afb3ae5ae0c602c47 141 Pfam PF00571 CBS domain 3 53 2.6E-10 T 13-10-2018 IPR000644 CBS domain Astex_0804 743d221bc6b7960afb3ae5ae0c602c47 141 Pfam PF00571 CBS domain 67 120 3.0E-10 T 13-10-2018 IPR000644 CBS domain Astex_2126 b8705c4000ae05e694a8872d5291597b 519 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 17 61 8.0E-10 T 13-10-2018 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal Astex_2126 b8705c4000ae05e694a8872d5291597b 519 SUPERFAMILY SSF53300 125 511 3.99E-24 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Astex_2126 b8705c4000ae05e694a8872d5291597b 519 SMART SM00327 143 506 2.0E-7 T 13-10-2018 IPR002035 von Willebrand factor, type A Astex_2126 b8705c4000ae05e694a8872d5291597b 519 Gene3D G3DSA:3.40.50.410 336 515 1.3E-19 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Astex_2126 b8705c4000ae05e694a8872d5291597b 519 Gene3D G3DSA:3.40.50.410 137 294 2.7E-9 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Astex_2126 b8705c4000ae05e694a8872d5291597b 519 Pfam PF00092 von Willebrand factor type A domain 146 203 1.6E-5 T 13-10-2018 IPR002035 von Willebrand factor, type A Astex_2126 b8705c4000ae05e694a8872d5291597b 519 Pfam PF00092 von Willebrand factor type A domain 376 505 2.2E-8 T 13-10-2018 IPR002035 von Willebrand factor, type A Astex_0153 4cbfb769ca1550b492b3a50a541e0ea5 168 SUPERFAMILY SSF54611 27 157 1.92E-42 T 13-10-2018 IPR035958 SecB-like superfamily Astex_0153 4cbfb769ca1550b492b3a50a541e0ea5 168 Pfam PF02556 Preprotein translocase subunit SecB 26 159 2.6E-46 T 13-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 Astex_0153 4cbfb769ca1550b492b3a50a541e0ea5 168 Gene3D G3DSA:3.10.420.10 10 168 7.3E-47 T 13-10-2018 IPR035958 SecB-like superfamily Astex_0153 4cbfb769ca1550b492b3a50a541e0ea5 168 TIGRFAM TIGR00809 secB: protein-export chaperone SecB 26 158 8.9E-38 T 13-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 Astex_0153 4cbfb769ca1550b492b3a50a541e0ea5 168 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 29 46 1.5E-16 T 13-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 Astex_0153 4cbfb769ca1550b492b3a50a541e0ea5 168 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 113 135 1.5E-16 T 13-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 Astex_0153 4cbfb769ca1550b492b3a50a541e0ea5 168 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 89 109 1.5E-16 T 13-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 Astex_0153 4cbfb769ca1550b492b3a50a541e0ea5 168 Hamap MF_00821 Protein-export protein SecB [secB]. 1 162 27.006 T 13-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 Astex_2329 b3227d6fa6c88a011cbfcb15f1814b25 622 Pfam PF00563 EAL domain 372 603 1.1E-71 T 13-10-2018 IPR001633 EAL domain Astex_2329 b3227d6fa6c88a011cbfcb15f1814b25 622 Gene3D G3DSA:3.30.70.270 194 369 1.5E-56 T 13-10-2018 Astex_2329 b3227d6fa6c88a011cbfcb15f1814b25 622 Gene3D G3DSA:3.30.450.20 58 193 1.3E-9 T 13-10-2018 Astex_2329 b3227d6fa6c88a011cbfcb15f1814b25 622 Pfam PF00990 Diguanylate cyclase, GGDEF domain 196 351 1.8E-47 T 13-10-2018 IPR000160 GGDEF domain Astex_2329 b3227d6fa6c88a011cbfcb15f1814b25 622 SMART SM00267 185 356 2.5E-56 T 13-10-2018 IPR000160 GGDEF domain Astex_2329 b3227d6fa6c88a011cbfcb15f1814b25 622 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 192 355 8.0E-38 T 13-10-2018 IPR000160 GGDEF domain Astex_2329 b3227d6fa6c88a011cbfcb15f1814b25 622 Pfam PF12860 PAS fold 78 188 2.3E-9 T 13-10-2018 Astex_2329 b3227d6fa6c88a011cbfcb15f1814b25 622 SUPERFAMILY SSF55785 59 183 7.54E-10 T 13-10-2018 IPR035965 PAS domain superfamily Astex_2329 b3227d6fa6c88a011cbfcb15f1814b25 622 SUPERFAMILY SSF141868 372 610 1.05E-88 T 13-10-2018 IPR035919 EAL domain superfamily Astex_2329 b3227d6fa6c88a011cbfcb15f1814b25 622 Gene3D G3DSA:3.20.20.450 370 619 6.1E-96 T 13-10-2018 IPR035919 EAL domain superfamily Astex_2329 b3227d6fa6c88a011cbfcb15f1814b25 622 SUPERFAMILY SSF55073 201 357 4.0E-45 T 13-10-2018 IPR029787 Nucleotide cyclase Astex_2329 b3227d6fa6c88a011cbfcb15f1814b25 622 SMART SM00052 366 608 3.2E-112 T 13-10-2018 IPR001633 EAL domain Astex_3629 1cb6b5d66446695a25a052ee55f30b8f 448 Pfam PF13701 Transposase DDE domain group 1 12 447 9.6E-161 T 13-10-2018 IPR025668 Transposase DDE domain Astex_3629 1cb6b5d66446695a25a052ee55f30b8f 448 SUPERFAMILY SSF53098 156 406 1.29E-5 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily Astex_2439 1cb6b5d66446695a25a052ee55f30b8f 448 Pfam PF13701 Transposase DDE domain group 1 12 447 9.6E-161 T 13-10-2018 IPR025668 Transposase DDE domain Astex_2439 1cb6b5d66446695a25a052ee55f30b8f 448 SUPERFAMILY SSF53098 156 406 1.29E-5 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily Astex_2449 9c1456fe24ba1dbe183e87f9b57533e5 202 Gene3D G3DSA:1.10.10.10 2 69 4.5E-14 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_2449 9c1456fe24ba1dbe183e87f9b57533e5 202 SUPERFAMILY SSF46785 7 72 2.04E-9 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_2449 9c1456fe24ba1dbe183e87f9b57533e5 202 SMART SM00345 11 69 3.8E-5 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Astex_2449 9c1456fe24ba1dbe183e87f9b57533e5 202 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 68 3.9E-11 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Astex_1922 8b2dab76de3ced57f5d485d57b94fde6 101 Gene3D G3DSA:1.10.10.10 6 100 1.2E-23 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1922 8b2dab76de3ced57f5d485d57b94fde6 101 SUPERFAMILY SSF46785 12 98 9.6E-14 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_1922 8b2dab76de3ced57f5d485d57b94fde6 101 Pfam PF13601 Winged helix DNA-binding domain 18 97 6.5E-32 T 13-10-2018 IPR027395 Winged helix DNA-binding domain Astex_1638 c7d43173c3a5bb0b6ce90fb26e153e58 195 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 5 185 5.8E-32 T 13-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase Astex_1638 c7d43173c3a5bb0b6ce90fb26e153e58 195 Gene3D G3DSA:3.40.50.10420 1 193 1.3E-44 T 13-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily Astex_1638 c7d43173c3a5bb0b6ce90fb26e153e58 195 SUPERFAMILY SSF100950 5 191 6.28E-45 T 13-10-2018 IPR037171 NagB/RpiA transferase-like Astex_1638 c7d43173c3a5bb0b6ce90fb26e153e58 195 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 5 185 1.4E-40 T 13-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase Astex_1638 c7d43173c3a5bb0b6ce90fb26e153e58 195 PIRSF PIRSF006806 1 188 1.0E-33 T 13-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase Astex_1415 841ed2ec3174662e8393f559f10e21e7 717 Gene3D G3DSA:3.30.450.20 227 325 6.0E-8 T 13-10-2018 Astex_1415 841ed2ec3174662e8393f559f10e21e7 717 SUPERFAMILY SSF55874 390 568 6.02E-34 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_1415 841ed2ec3174662e8393f559f10e21e7 717 SMART SM00388 334 400 0.0035 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_1415 841ed2ec3174662e8393f559f10e21e7 717 SMART SM00448 599 711 4.3E-27 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1415 841ed2ec3174662e8393f559f10e21e7 717 Gene3D G3DSA:3.30.565.10 401 574 2.8E-43 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_1415 841ed2ec3174662e8393f559f10e21e7 717 PRINTS PR00344 Bacterial sensor protein C-terminal signature 526 544 1.4E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1415 841ed2ec3174662e8393f559f10e21e7 717 PRINTS PR00344 Bacterial sensor protein C-terminal signature 554 567 1.4E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1415 841ed2ec3174662e8393f559f10e21e7 717 PRINTS PR00344 Bacterial sensor protein C-terminal signature 513 523 1.4E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1415 841ed2ec3174662e8393f559f10e21e7 717 PRINTS PR00344 Bacterial sensor protein C-terminal signature 495 509 1.4E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1415 841ed2ec3174662e8393f559f10e21e7 717 SUPERFAMILY SSF55785 239 327 5.41E-7 T 13-10-2018 IPR035965 PAS domain superfamily Astex_1415 841ed2ec3174662e8393f559f10e21e7 717 SUPERFAMILY SSF47384 327 397 6.08E-10 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Astex_1415 841ed2ec3174662e8393f559f10e21e7 717 Gene3D G3DSA:1.10.287.130 326 399 2.1E-17 T 13-10-2018 Astex_1415 841ed2ec3174662e8393f559f10e21e7 717 Pfam PF00072 Response regulator receiver domain 601 711 2.6E-18 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1415 841ed2ec3174662e8393f559f10e21e7 717 Gene3D G3DSA:3.40.50.2300 589 717 1.3E-27 T 13-10-2018 Astex_1415 841ed2ec3174662e8393f559f10e21e7 717 SUPERFAMILY SSF52172 600 715 1.05E-28 T 13-10-2018 IPR011006 CheY-like superfamily Astex_1415 841ed2ec3174662e8393f559f10e21e7 717 SMART SM00387 441 570 2.6E-27 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_1415 841ed2ec3174662e8393f559f10e21e7 717 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 442 567 8.7E-17 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_0067 2fc64badc7378f920df6f06603fb79a3 259 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 21 259 35.195 T 13-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 Astex_0067 2fc64badc7378f920df6f06603fb79a3 259 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 30 257 1.4E-76 T 13-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 Astex_0067 2fc64badc7378f920df6f06603fb79a3 259 Gene3D G3DSA:3.40.50.150 36 259 6.0E-69 T 13-10-2018 Astex_0067 2fc64badc7378f920df6f06603fb79a3 259 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 167 181 - T 13-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 Astex_0067 2fc64badc7378f920df6f06603fb79a3 259 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 41 56 - T 13-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 Astex_0067 2fc64badc7378f920df6f06603fb79a3 259 SUPERFAMILY SSF53335 11 240 2.6E-40 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Astex_0067 2fc64badc7378f920df6f06603fb79a3 259 Pfam PF01209 ubiE/COQ5 methyltransferase family 25 258 5.0E-82 T 13-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 Astex_2669 98c83665176828036800bb8e845a9c50 239 TIGRFAM TIGR02780 TrbJ_Ti: P-type conjugative transfer protein TrbJ 3 235 4.6E-46 T 13-10-2018 IPR014147 Type IV conjugative transfer protein TrbJ Astex_0964 c41af5fb9650ec7e1f5b964127eaaf08 159 ProSitePatterns PS00475 Ribosomal protein L15 signature. 116 146 - T 13-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0964 c41af5fb9650ec7e1f5b964127eaaf08 159 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 4 152 20.216 T 13-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 Astex_0964 c41af5fb9650ec7e1f5b964127eaaf08 159 SUPERFAMILY SSF52080 5 149 4.32E-43 T 13-10-2018 IPR036227 Ribosomal L18e/L15P superfamily Astex_0964 c41af5fb9650ec7e1f5b964127eaaf08 159 Gene3D G3DSA:3.100.10.10 67 151 3.5E-17 T 13-10-2018 Astex_0964 c41af5fb9650ec7e1f5b964127eaaf08 159 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 149 5.7E-36 T 13-10-2018 IPR021131 Ribosomal protein L18e/L15P Astex_0964 c41af5fb9650ec7e1f5b964127eaaf08 159 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 3 149 1.1E-45 T 13-10-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_2666 7fc466a8cdfaab51008c50c012f6ba23 111 Pfam PF04956 TrbC/VIRB2 family 9 102 2.6E-25 T 13-10-2018 IPR007039 Conjugal transfer TrbC/type IV secretion VirB2 Astex_3600 53360eb2e56043737c5769db2066fa6f 903 Gene3D G3DSA:2.60.40.10 795 903 4.0E-35 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_3600 53360eb2e56043737c5769db2066fa6f 903 Gene3D G3DSA:2.60.40.10 706 791 1.6E-23 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_3600 53360eb2e56043737c5769db2066fa6f 903 Pfam PF00703 Glycosyl hydrolases family 2 267 381 7.5E-15 T 13-10-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_3600 53360eb2e56043737c5769db2066fa6f 903 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 388 546 1.4E-28 T 13-10-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 Astex_3600 53360eb2e56043737c5769db2066fa6f 903 SUPERFAMILY SSF49785 34 278 2.31E-41 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_3600 53360eb2e56043737c5769db2066fa6f 903 Gene3D G3DSA:2.60.120.260 104 258 5.5E-40 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_3600 53360eb2e56043737c5769db2066fa6f 903 PRINTS PR00132 Glycosyl hydrolase family 2 signature 424 442 1.6E-10 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_3600 53360eb2e56043737c5769db2066fa6f 903 PRINTS PR00132 Glycosyl hydrolase family 2 signature 494 509 1.6E-10 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_3600 53360eb2e56043737c5769db2066fa6f 903 PRINTS PR00132 Glycosyl hydrolase family 2 signature 393 407 1.6E-10 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_3600 53360eb2e56043737c5769db2066fa6f 903 PRINTS PR00132 Glycosyl hydrolase family 2 signature 190 205 1.6E-10 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_3600 53360eb2e56043737c5769db2066fa6f 903 ProSitePatterns PS00608 Glycosyl hydrolases family 2 acid/base catalyst. 494 508 - T 13-10-2018 IPR023232 Glycoside hydrolase, family 2, active site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_3600 53360eb2e56043737c5769db2066fa6f 903 Gene3D G3DSA:3.20.20.80 383 704 5.7E-110 T 13-10-2018 Astex_3600 53360eb2e56043737c5769db2066fa6f 903 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 118 257 1.9E-13 T 13-10-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_3600 53360eb2e56043737c5769db2066fa6f 903 Gene3D G3DSA:2.60.40.10 259 381 4.1E-27 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_3600 53360eb2e56043737c5769db2066fa6f 903 SUPERFAMILY SSF49303 269 381 6.12E-13 T 13-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily Astex_3600 53360eb2e56043737c5769db2066fa6f 903 SUPERFAMILY SSF51445 378 700 3.37E-76 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_3600 53360eb2e56043737c5769db2066fa6f 903 Pfam PF16355 Domain of unknown function (DUF4982) 724 784 7.6E-23 T 13-10-2018 IPR032311 Domain of unknown function DUF4982 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_3195 e30eb05794d3b8963cb9e8d896b95314 216 Pfam PF01545 Cation efflux family 37 214 2.3E-11 T 13-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 Astex_3195 e30eb05794d3b8963cb9e8d896b95314 216 SUPERFAMILY SSF161111 31 214 1.83E-31 T 13-10-2018 IPR027469 Cation efflux transmembrane domain superfamily Astex_3195 e30eb05794d3b8963cb9e8d896b95314 216 Gene3D G3DSA:1.20.1510.10 32 214 7.9E-9 T 13-10-2018 IPR027469 Cation efflux transmembrane domain superfamily Astex_1626 f66fcea6010c95d8db51a2455c420f3e 431 Gene3D G3DSA:1.10.510.10 304 430 4.8E-16 T 13-10-2018 Astex_1626 f66fcea6010c95d8db51a2455c420f3e 431 Pfam PF13855 Leucine rich repeat 128 183 1.9E-7 T 13-10-2018 IPR001611 Leucine-rich repeat GO:0005515 Astex_1626 f66fcea6010c95d8db51a2455c420f3e 431 SUPERFAMILY SSF52058 24 185 9.18E-30 T 13-10-2018 Astex_1626 f66fcea6010c95d8db51a2455c420f3e 431 Gene3D G3DSA:3.30.200.20 198 288 7.4E-7 T 13-10-2018 Astex_1626 f66fcea6010c95d8db51a2455c420f3e 431 Gene3D G3DSA:3.80.10.10 3 197 8.5E-33 T 13-10-2018 IPR032675 Leucine-rich repeat domain superfamily Astex_1626 f66fcea6010c95d8db51a2455c420f3e 431 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 211 236 - T 13-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 Astex_1626 f66fcea6010c95d8db51a2455c420f3e 431 Pfam PF07714 Protein tyrosine kinase 205 381 1.2E-14 T 13-10-2018 IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domain GO:0004672|GO:0006468 Astex_1626 f66fcea6010c95d8db51a2455c420f3e 431 SUPERFAMILY SSF56112 200 426 1.89E-30 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily Astex_0159 600b53b31613b8e0af4719941d790424 1596 SUPERFAMILY SSF53223 754 939 1.29E-20 T 13-10-2018 Astex_0159 600b53b31613b8e0af4719941d790424 1596 SUPERFAMILY SSF51735 944 1227 4.99E-27 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_0159 600b53b31613b8e0af4719941d790424 1596 PIRSF PIRSF036761 8 1596 0.0 T 13-10-2018 IPR007780 NAD-glutamate dehydrogenase, bacteria GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 Astex_0159 600b53b31613b8e0af4719941d790424 1596 Pfam PF05088 Bacterial NAD-glutamate dehydrogenase 88 1590 0.0 T 13-10-2018 IPR028971 NAD-glutamate dehydrogenase GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 Astex_0111 a35ba73ed37a5bc54a51a2a435dc6fb6 470 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 11 445 59.841 T 13-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 Astex_0111 a35ba73ed37a5bc54a51a2a435dc6fb6 470 Gene3D G3DSA:3.40.50.12160 12 130 1.4E-27 T 13-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily Astex_0111 a35ba73ed37a5bc54a51a2a435dc6fb6 470 Gene3D G3DSA:2.40.50.140 384 447 7.9E-16 T 13-10-2018 Astex_0111 a35ba73ed37a5bc54a51a2a435dc6fb6 470 SMART SM00729 144 369 6.8E-45 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Astex_0111 a35ba73ed37a5bc54a51a2a435dc6fb6 470 SUPERFAMILY SSF102114 135 373 2.62E-46 T 13-10-2018 Astex_0111 a35ba73ed37a5bc54a51a2a435dc6fb6 470 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 12 443 3.5E-97 T 13-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 Astex_0111 a35ba73ed37a5bc54a51a2a435dc6fb6 470 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 148 168 - T 13-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 Astex_0111 a35ba73ed37a5bc54a51a2a435dc6fb6 470 Gene3D G3DSA:3.80.30.20 142 383 9.6E-66 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe Astex_0111 a35ba73ed37a5bc54a51a2a435dc6fb6 470 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 12 443 3.2E-171 T 13-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 Astex_0111 a35ba73ed37a5bc54a51a2a435dc6fb6 470 Pfam PF00919 Uncharacterized protein family UPF0004 12 105 5.0E-19 T 13-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 Astex_0111 a35ba73ed37a5bc54a51a2a435dc6fb6 470 Pfam PF04055 Radical SAM superfamily 150 327 4.7E-25 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Astex_3585 cdc2b74bc0aabb531fcac59a28ce881b 225 TIGRFAM TIGR02842 CyoC: cytochrome o ubiquinol oxidase, subunit III 47 224 1.5E-82 T 13-10-2018 IPR014206 Cytochrome o ubiquinol oxidase, subunit III GO:0005886|GO:0008827|GO:0019646 Astex_3585 cdc2b74bc0aabb531fcac59a28ce881b 225 Pfam PF00510 Cytochrome c oxidase subunit III 36 223 7.4E-13 T 13-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_3585 cdc2b74bc0aabb531fcac59a28ce881b 225 Gene3D G3DSA:1.20.120.80 40 225 1.1E-57 T 13-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_3585 cdc2b74bc0aabb531fcac59a28ce881b 225 SUPERFAMILY SSF81452 32 223 9.03E-58 T 13-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_2220 34a1ee754f031303422689356418fa6d 240 Pfam PF02397 Bacterial sugar transferase 44 234 3.3E-60 T 13-10-2018 IPR003362 Bacterial sugar transferase Astex_2629 0d906130d1511d0854e352175264445c 555 Gene3D G3DSA:3.40.50.620 60 310 1.6E-64 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Astex_2629 0d906130d1511d0854e352175264445c 555 Pfam PF01921 tRNA synthetases class I (K) 60 393 1.3E-115 T 13-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 Astex_2629 0d906130d1511d0854e352175264445c 555 Hamap MF_00177 Lysine--tRNA ligase [lysS]. 13 550 28.778 T 13-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 Astex_2629 0d906130d1511d0854e352175264445c 555 Gene3D G3DSA:1.10.10.350 458 549 4.9E-19 T 13-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 Astex_2629 0d906130d1511d0854e352175264445c 555 SUPERFAMILY SSF48163 358 548 1.13E-39 T 13-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 Astex_2629 0d906130d1511d0854e352175264445c 555 SUPERFAMILY SSF52374 61 359 3.29E-49 T 13-10-2018 Astex_2629 0d906130d1511d0854e352175264445c 555 Gene3D G3DSA:2.30.30.300 213 257 1.6E-64 T 13-10-2018 IPR023386 Lysine-tRNA ligase, insertion domain superfamily GO:0004824 KEGG: 00970+6.1.1.6 Astex_2629 0d906130d1511d0854e352175264445c 555 TIGRFAM TIGR00467 lysS_arch: lysine--tRNA ligase 67 541 9.6E-46 T 13-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 Astex_2629 0d906130d1511d0854e352175264445c 555 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 72 81 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Astex_3809 580846b8965cff21181a1c86ae1be0b2 404 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 211 230 - T 13-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site Astex_3809 580846b8965cff21181a1c86ae1be0b2 404 Gene3D G3DSA:3.40.640.10 76 254 5.5E-114 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Astex_3809 580846b8965cff21181a1c86ae1be0b2 404 Gene3D G3DSA:3.90.1150.10 20 381 5.5E-114 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Astex_3809 580846b8965cff21181a1c86ae1be0b2 404 Gene3D G3DSA:1.10.260.50 31 297 5.5E-114 T 13-10-2018 Astex_3809 580846b8965cff21181a1c86ae1be0b2 404 Pfam PF00266 Aminotransferase class-V 20 380 5.1E-68 T 13-10-2018 IPR000192 Aminotransferase class V domain Astex_3809 580846b8965cff21181a1c86ae1be0b2 404 PIRSF PIRSF005572 17 398 1.2E-111 T 13-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 Astex_3809 580846b8965cff21181a1c86ae1be0b2 404 SUPERFAMILY SSF53383 19 391 2.15E-89 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Astex_2575 17e3e898ad0ddbf6fbb5c17a4ba96f9c 344 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 133 239 1.6E-14 T 13-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 Astex_2575 17e3e898ad0ddbf6fbb5c17a4ba96f9c 344 Gene3D G3DSA:3.30.360.10 126 328 2.9E-124 T 13-10-2018 Astex_2575 17e3e898ad0ddbf6fbb5c17a4ba96f9c 344 SUPERFAMILY SSF51735 2 197 9.85E-43 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_2575 17e3e898ad0ddbf6fbb5c17a4ba96f9c 344 Gene3D G3DSA:3.40.50.720 6 315 2.9E-124 T 13-10-2018 Astex_2575 17e3e898ad0ddbf6fbb5c17a4ba96f9c 344 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 7 119 5.8E-21 T 13-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 Astex_3378 dcfc21e4843d85ce561c8bad8cfb8a78 1058 PRINTS PR00702 Acriflavin resistance protein family signature 446 469 2.2E-110 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3378 dcfc21e4843d85ce561c8bad8cfb8a78 1058 PRINTS PR00702 Acriflavin resistance protein family signature 337 360 2.2E-110 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3378 dcfc21e4843d85ce561c8bad8cfb8a78 1058 PRINTS PR00702 Acriflavin resistance protein family signature 471 494 2.2E-110 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3378 dcfc21e4843d85ce561c8bad8cfb8a78 1058 PRINTS PR00702 Acriflavin resistance protein family signature 9 33 2.2E-110 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3378 dcfc21e4843d85ce561c8bad8cfb8a78 1058 PRINTS PR00702 Acriflavin resistance protein family signature 392 416 2.2E-110 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3378 dcfc21e4843d85ce561c8bad8cfb8a78 1058 PRINTS PR00702 Acriflavin resistance protein family signature 553 570 2.2E-110 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3378 dcfc21e4843d85ce561c8bad8cfb8a78 1058 PRINTS PR00702 Acriflavin resistance protein family signature 37 55 2.2E-110 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3378 dcfc21e4843d85ce561c8bad8cfb8a78 1058 PRINTS PR00702 Acriflavin resistance protein family signature 620 634 2.2E-110 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3378 dcfc21e4843d85ce561c8bad8cfb8a78 1058 PRINTS PR00702 Acriflavin resistance protein family signature 364 385 2.2E-110 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3378 dcfc21e4843d85ce561c8bad8cfb8a78 1058 SUPERFAMILY SSF82693 671 855 2.88E-29 T 13-10-2018 Astex_3378 dcfc21e4843d85ce561c8bad8cfb8a78 1058 SUPERFAMILY SSF82714 183 273 1.83E-22 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Astex_3378 dcfc21e4843d85ce561c8bad8cfb8a78 1058 SUPERFAMILY SSF82866 831 1025 2.22E-43 T 13-10-2018 Astex_3378 dcfc21e4843d85ce561c8bad8cfb8a78 1058 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 3 1035 0.0 T 13-10-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0006855|GO:0015562|GO:0016021 Astex_3378 dcfc21e4843d85ce561c8bad8cfb8a78 1058 Gene3D G3DSA:3.30.70.1320 134 333 0.0 T 13-10-2018 Astex_3378 dcfc21e4843d85ce561c8bad8cfb8a78 1058 SUPERFAMILY SSF82866 297 498 3.66E-50 T 13-10-2018 Astex_3378 dcfc21e4843d85ce561c8bad8cfb8a78 1058 SUPERFAMILY SSF82714 721 807 6.02E-22 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Astex_3378 dcfc21e4843d85ce561c8bad8cfb8a78 1058 Pfam PF00873 AcrB/AcrD/AcrF family 2 1024 0.0 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 Astex_3378 dcfc21e4843d85ce561c8bad8cfb8a78 1058 Gene3D G3DSA:1.20.1640.10 9 513 0.0 T 13-10-2018 Astex_3378 dcfc21e4843d85ce561c8bad8cfb8a78 1058 SUPERFAMILY SSF82693 566 668 1.57E-30 T 13-10-2018 Astex_3378 dcfc21e4843d85ce561c8bad8cfb8a78 1058 Gene3D G3DSA:3.30.70.1430 39 816 0.0 T 13-10-2018 Astex_3378 dcfc21e4843d85ce561c8bad8cfb8a78 1058 Gene3D G3DSA:3.30.70.1440 668 864 0.0 T 13-10-2018 Astex_3378 dcfc21e4843d85ce561c8bad8cfb8a78 1058 Gene3D G3DSA:1.20.1640.10 514 1021 0.0 T 13-10-2018 Astex_3378 dcfc21e4843d85ce561c8bad8cfb8a78 1058 SUPERFAMILY SSF82693 39 132 5.93E-29 T 13-10-2018 Astex_3378 dcfc21e4843d85ce561c8bad8cfb8a78 1058 Gene3D G3DSA:3.30.70.1430 568 667 0.0 T 13-10-2018 Astex_3378 dcfc21e4843d85ce561c8bad8cfb8a78 1058 Gene3D G3DSA:3.30.2090.10 720 808 0.0 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Astex_3378 dcfc21e4843d85ce561c8bad8cfb8a78 1058 Gene3D G3DSA:3.30.2090.10 180 276 0.0 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Astex_3378 dcfc21e4843d85ce561c8bad8cfb8a78 1058 SUPERFAMILY SSF82693 136 331 5.23E-26 T 13-10-2018 Astex_3677 f402c62735ad12bf1daa8a907a34e1a2 383 SUPERFAMILY SSF54826 8 115 1.77E-29 T 13-10-2018 Astex_3677 f402c62735ad12bf1daa8a907a34e1a2 383 SUPERFAMILY SSF51604 98 362 4.06E-73 T 13-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily Astex_3677 f402c62735ad12bf1daa8a907a34e1a2 383 SMART SM00922 128 230 1.5E-15 T 13-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal Astex_3677 f402c62735ad12bf1daa8a907a34e1a2 383 Pfam PF13378 Enolase C-terminal domain-like 133 356 2.4E-58 T 13-10-2018 IPR029065 Enolase C-terminal domain-like Astex_3677 f402c62735ad12bf1daa8a907a34e1a2 383 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 85 110 - T 13-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 Astex_3677 f402c62735ad12bf1daa8a907a34e1a2 383 Gene3D G3DSA:3.30.390.10 14 373 4.8E-142 T 13-10-2018 IPR029017 Enolase-like, N-terminal Astex_3677 f402c62735ad12bf1daa8a907a34e1a2 383 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 18 110 2.0E-22 T 13-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain Astex_3677 f402c62735ad12bf1daa8a907a34e1a2 383 Gene3D G3DSA:3.20.20.120 105 345 4.8E-142 T 13-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily Astex_2284 1ee636d6b46e1e29dac01c4bc4cc3d73 332 Pfam PF01380 SIS domain 57 182 7.9E-26 T 13-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 Astex_2284 1ee636d6b46e1e29dac01c4bc4cc3d73 332 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 57 322 6.6E-85 T 13-10-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 Astex_2284 1ee636d6b46e1e29dac01c4bc4cc3d73 332 Gene3D G3DSA:3.10.580.10 208 329 6.1E-39 T 13-10-2018 Astex_2284 1ee636d6b46e1e29dac01c4bc4cc3d73 332 Gene3D G3DSA:3.40.50.10490 8 207 2.9E-54 T 13-10-2018 Astex_2284 1ee636d6b46e1e29dac01c4bc4cc3d73 332 SUPERFAMILY SSF53697 37 308 2.89E-55 T 13-10-2018 Astex_2284 1ee636d6b46e1e29dac01c4bc4cc3d73 332 SMART SM00116 221 269 0.44 T 13-10-2018 IPR000644 CBS domain Astex_2284 1ee636d6b46e1e29dac01c4bc4cc3d73 332 SMART SM00116 284 331 26.0 T 13-10-2018 IPR000644 CBS domain Astex_2284 1ee636d6b46e1e29dac01c4bc4cc3d73 332 PIRSF PIRSF004692 2 332 8.4E-119 T 13-10-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 Astex_2284 1ee636d6b46e1e29dac01c4bc4cc3d73 332 Pfam PF00571 CBS domain 277 329 3.2E-6 T 13-10-2018 IPR000644 CBS domain Astex_2284 1ee636d6b46e1e29dac01c4bc4cc3d73 332 Pfam PF00571 CBS domain 212 269 1.3E-4 T 13-10-2018 IPR000644 CBS domain Astex_2317 a01818987c9bc8b86a8fbe731bd608f4 545 Pfam PF07690 Major Facilitator Superfamily 19 430 1.2E-49 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Astex_2317 a01818987c9bc8b86a8fbe731bd608f4 545 SUPERFAMILY SSF103473 5 518 1.31E-64 T 13-10-2018 IPR036259 MFS transporter superfamily Astex_2317 a01818987c9bc8b86a8fbe731bd608f4 545 Gene3D G3DSA:1.20.1720.10 15 243 3.3E-47 T 13-10-2018 Astex_2317 a01818987c9bc8b86a8fbe731bd608f4 545 Gene3D G3DSA:1.20.1250.20 276 447 2.0E-22 T 13-10-2018 Astex_0064 3e5f0a62e0e1b7e0bb44f04069225181 325 SUPERFAMILY SSF143865 1 264 9.94E-28 T 13-10-2018 Astex_0064 3e5f0a62e0e1b7e0bb44f04069225181 325 Gene3D G3DSA:1.20.58.340 249 325 5.1E-26 T 13-10-2018 Astex_0064 3e5f0a62e0e1b7e0bb44f04069225181 325 SUPERFAMILY SSF144083 260 322 1.7E-19 T 13-10-2018 Astex_0064 3e5f0a62e0e1b7e0bb44f04069225181 325 Pfam PF01544 CorA-like Mg2+ transporter protein 27 321 2.8E-46 T 13-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 Astex_1306 857075870ba189276ed1c34a4ad3a42d 334 SUPERFAMILY SSF53474 91 326 1.69E-37 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1306 857075870ba189276ed1c34a4ad3a42d 334 Gene3D G3DSA:3.40.50.1820 80 333 3.6E-55 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1306 857075870ba189276ed1c34a4ad3a42d 334 Pfam PF00326 Prolyl oligopeptidase family 165 329 2.8E-12 T 13-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 Astex_2558 592529e8cd2e98d2113e201d78763365 575 SUPERFAMILY SSF53335 37 197 1.45E-7 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Astex_2558 592529e8cd2e98d2113e201d78763365 575 SUPERFAMILY SSF54373 425 495 5.23E-5 T 13-10-2018 Astex_2558 592529e8cd2e98d2113e201d78763365 575 Pfam PF01266 FAD dependent oxidoreductase 242 546 7.1E-19 T 13-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 Astex_2558 592529e8cd2e98d2113e201d78763365 575 SUPERFAMILY SSF51971 239 554 8.12E-16 T 13-10-2018 Astex_2558 592529e8cd2e98d2113e201d78763365 575 Hamap MF_01102 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC [mnmC]. 3 572 19.724 T 13-10-2018 IPR023032 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC GO:0004808|GO:0008033|GO:0008168|GO:0016645|GO:0055114 MetaCyc: PWY-7892 Astex_2558 592529e8cd2e98d2113e201d78763365 575 Pfam PF05430 S-adenosyl-L-methionine-dependent methyltransferase 108 229 1.2E-41 T 13-10-2018 IPR008471 MnmC-like methyltransferase GO:0016645|GO:0055114 MetaCyc: PWY-7892 Astex_2558 592529e8cd2e98d2113e201d78763365 575 Gene3D G3DSA:3.30.9.10 318 510 1.5E-49 T 13-10-2018 Astex_2558 592529e8cd2e98d2113e201d78763365 575 Gene3D G3DSA:3.40.50.150 5 234 6.7E-84 T 13-10-2018 Astex_2558 592529e8cd2e98d2113e201d78763365 575 Gene3D G3DSA:3.50.50.60 242 569 1.5E-49 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_0245 046a5e883ade76587235ffeb1ef75f95 2500 Gene3D G3DSA:3.80.10.10 4 253 3.5E-9 T 13-10-2018 IPR032675 Leucine-rich repeat domain superfamily Astex_0245 046a5e883ade76587235ffeb1ef75f95 2500 Gene3D G3DSA:3.80.10.10 882 1220 5.9E-18 T 13-10-2018 IPR032675 Leucine-rich repeat domain superfamily Astex_0245 046a5e883ade76587235ffeb1ef75f95 2500 Gene3D G3DSA:3.80.10.10 1617 1998 2.8E-29 T 13-10-2018 IPR032675 Leucine-rich repeat domain superfamily Astex_0245 046a5e883ade76587235ffeb1ef75f95 2500 Gene3D G3DSA:3.80.10.10 2347 2500 2.8E-9 T 13-10-2018 IPR032675 Leucine-rich repeat domain superfamily Astex_0245 046a5e883ade76587235ffeb1ef75f95 2500 Gene3D G3DSA:3.80.10.10 254 599 5.0E-22 T 13-10-2018 IPR032675 Leucine-rich repeat domain superfamily Astex_0245 046a5e883ade76587235ffeb1ef75f95 2500 Gene3D G3DSA:3.80.10.10 2043 2343 6.8E-18 T 13-10-2018 IPR032675 Leucine-rich repeat domain superfamily Astex_0245 046a5e883ade76587235ffeb1ef75f95 2500 Gene3D G3DSA:3.80.10.10 1281 1567 1.9E-19 T 13-10-2018 IPR032675 Leucine-rich repeat domain superfamily Astex_0245 046a5e883ade76587235ffeb1ef75f95 2500 Gene3D G3DSA:3.80.10.10 600 881 1.7E-17 T 13-10-2018 IPR032675 Leucine-rich repeat domain superfamily Astex_2442 d1a7c865aa36aec2101d0618955b5a7a 773 SUPERFAMILY SSF52540 4 619 9.52E-18 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2442 d1a7c865aa36aec2101d0618955b5a7a 773 Pfam PF13166 AAA domain 249 617 1.2E-28 T 13-10-2018 IPR026866 Protein CR006, P-loop domain Astex_2442 d1a7c865aa36aec2101d0618955b5a7a 773 Gene3D G3DSA:3.40.50.300 301 623 6.2E-17 T 13-10-2018 Astex_3129 061fab0296ca061d145d5829f4fb110a 223 Pfam PF00535 Glycosyl transferase family 2 3 102 8.0E-15 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 Astex_3129 061fab0296ca061d145d5829f4fb110a 223 SUPERFAMILY SSF53448 1 196 1.79E-29 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_3129 061fab0296ca061d145d5829f4fb110a 223 Gene3D G3DSA:3.90.550.10 1 187 3.7E-23 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_1474 ee197c7adfdb1c46a432930dbd0dd08c 558 SUPERFAMILY SSF52540 115 555 2.97E-51 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1474 ee197c7adfdb1c46a432930dbd0dd08c 558 Gene3D G3DSA:3.40.50.300 333 553 1.7E-47 T 13-10-2018 Astex_1474 ee197c7adfdb1c46a432930dbd0dd08c 558 Pfam PF02534 Type IV secretory system Conjugative DNA transfer 145 551 1.5E-82 T 13-10-2018 IPR003688 Type IV secretion system protein TraG/VirD4 GO:0009291|GO:0016020 Astex_1912 10ea43f40950a33fa6f57cb6a62b7807 391 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 216 355 4.8E-6 T 13-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 Astex_1912 10ea43f40950a33fa6f57cb6a62b7807 391 SUPERFAMILY SSF56529 157 356 4.84E-25 T 13-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 Astex_1912 10ea43f40950a33fa6f57cb6a62b7807 391 Gene3D G3DSA:3.90.850.10 143 361 3.1E-43 T 13-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 Astex_1791 f46ea1cc6b6e0e8f9e53eed30aa466b9 464 SUPERFAMILY SSF55931 122 461 6.47E-100 T 13-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Astex_1791 f46ea1cc6b6e0e8f9e53eed30aa466b9 464 SUPERFAMILY SSF54368 11 120 6.54E-12 T 13-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Astex_1791 f46ea1cc6b6e0e8f9e53eed30aa466b9 464 Gene3D G3DSA:3.30.590.10 119 460 2.9E-97 T 13-10-2018 Astex_1791 f46ea1cc6b6e0e8f9e53eed30aa466b9 464 Pfam PF00120 Glutamine synthetase, catalytic domain 123 460 1.0E-102 T 13-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Astex_1791 f46ea1cc6b6e0e8f9e53eed30aa466b9 464 SMART SM01230 122 379 4.2E-92 T 13-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Astex_0145 7f4e38a698f73265c7f83afbe91a6df2 341 Gene3D G3DSA:3.40.50.1400 159 297 2.0E-103 T 13-10-2018 Astex_0145 7f4e38a698f73265c7f83afbe91a6df2 341 SUPERFAMILY SSF53800 1 326 7.63E-98 T 13-10-2018 Astex_0145 7f4e38a698f73265c7f83afbe91a6df2 341 Gene3D G3DSA:3.40.50.1400 3 314 2.0E-103 T 13-10-2018 Astex_0145 7f4e38a698f73265c7f83afbe91a6df2 341 Pfam PF00762 Ferrochelatase 3 314 1.4E-101 T 13-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 Astex_0145 7f4e38a698f73265c7f83afbe91a6df2 341 Hamap MF_00323 Ferrochelatase [hemH]. 2 316 34.684 T 13-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 Astex_0145 7f4e38a698f73265c7f83afbe91a6df2 341 ProSitePatterns PS00534 Ferrochelatase signature. 187 207 - T 13-10-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 Astex_0145 7f4e38a698f73265c7f83afbe91a6df2 341 TIGRFAM TIGR00109 hemH: ferrochelatase 1 314 6.4E-86 T 13-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 Astex_0820 500ae0eab3e3f2573d69b6f670473d9f 490 Pfam PF03572 Peptidase family S41 259 440 1.3E-8 T 13-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 Astex_0820 500ae0eab3e3f2573d69b6f670473d9f 490 SUPERFAMILY SSF52096 73 445 6.63E-13 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Astex_2324 9fc3e93ebfcd4620692598fe3c31380c 381 ProSitePatterns PS00902 Glutamate 5-kinase signature. 223 240 - T 13-10-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 Astex_2324 9fc3e93ebfcd4620692598fe3c31380c 381 PRINTS PR00474 Glutamate 5-kinase family signature 56 70 5.8E-51 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 Astex_2324 9fc3e93ebfcd4620692598fe3c31380c 381 PRINTS PR00474 Glutamate 5-kinase family signature 90 118 5.8E-51 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 Astex_2324 9fc3e93ebfcd4620692598fe3c31380c 381 PRINTS PR00474 Glutamate 5-kinase family signature 225 245 5.8E-51 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 Astex_2324 9fc3e93ebfcd4620692598fe3c31380c 381 PRINTS PR00474 Glutamate 5-kinase family signature 130 151 5.8E-51 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 Astex_2324 9fc3e93ebfcd4620692598fe3c31380c 381 PRINTS PR00474 Glutamate 5-kinase family signature 162 189 5.8E-51 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 Astex_2324 9fc3e93ebfcd4620692598fe3c31380c 381 Gene3D G3DSA:2.30.130.10 281 381 3.3E-31 T 13-10-2018 IPR036974 PUA domain superfamily GO:0003723 Astex_2324 9fc3e93ebfcd4620692598fe3c31380c 381 SUPERFAMILY SSF88697 292 380 2.49E-22 T 13-10-2018 IPR015947 PUA-like superfamily Astex_2324 9fc3e93ebfcd4620692598fe3c31380c 381 Hamap MF_00456 Glutamate 5-kinase [proB]. 18 274 35.05 T 13-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 Astex_2324 9fc3e93ebfcd4620692598fe3c31380c 381 TIGRFAM TIGR01027 proB: glutamate 5-kinase 18 379 1.0E-120 T 13-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 Astex_2324 9fc3e93ebfcd4620692598fe3c31380c 381 Pfam PF00696 Amino acid kinase family 18 251 4.3E-37 T 13-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 Astex_2324 9fc3e93ebfcd4620692598fe3c31380c 381 Gene3D G3DSA:3.40.1160.10 9 278 1.7E-78 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Astex_2324 9fc3e93ebfcd4620692598fe3c31380c 381 SMART SM00359 292 373 4.5E-15 T 13-10-2018 IPR002478 PUA domain GO:0003723 Astex_2324 9fc3e93ebfcd4620692598fe3c31380c 381 PIRSF PIRSF000729 13 381 2.3E-118 T 13-10-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 Astex_2324 9fc3e93ebfcd4620692598fe3c31380c 381 Pfam PF01472 PUA domain 292 363 3.3E-19 T 13-10-2018 IPR002478 PUA domain GO:0003723 Astex_2324 9fc3e93ebfcd4620692598fe3c31380c 381 SUPERFAMILY SSF53633 18 270 1.13E-59 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Astex_1173 881415af019814433fb29b2b62930c93 451 SMART SM00382 64 180 1.4E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_1173 881415af019814433fb29b2b62930c93 451 Pfam PF12002 MgsA AAA+ ATPase C terminal 273 438 4.6E-65 T 13-10-2018 IPR021886 MgsA AAA+ ATPase C-terminal Astex_1173 881415af019814433fb29b2b62930c93 451 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 32 151 4.4E-14 T 13-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 Astex_1173 881415af019814433fb29b2b62930c93 451 SUPERFAMILY SSF48019 258 442 2.38E-71 T 13-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 Astex_1173 881415af019814433fb29b2b62930c93 451 Gene3D G3DSA:1.10.3710.10 351 450 4.7E-32 T 13-10-2018 Astex_1173 881415af019814433fb29b2b62930c93 451 Gene3D G3DSA:1.20.272.10 247 350 2.6E-42 T 13-10-2018 Astex_1173 881415af019814433fb29b2b62930c93 451 Gene3D G3DSA:3.40.50.300 20 179 6.9E-44 T 13-10-2018 Astex_1173 881415af019814433fb29b2b62930c93 451 SUPERFAMILY SSF52540 26 244 9.5E-43 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1173 881415af019814433fb29b2b62930c93 451 Pfam PF16193 AAA C-terminal domain 200 272 9.2E-17 T 13-10-2018 IPR032423 AAA C-terminal domain Astex_1713 1137e55f085bae7e58dedf5306f1aa9b 205 SUPERFAMILY SSF51391 4 201 3.01E-58 T 13-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Astex_1713 1137e55f085bae7e58dedf5306f1aa9b 205 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 4 195 2.3E-52 T 13-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Astex_1713 1137e55f085bae7e58dedf5306f1aa9b 205 Pfam PF02581 Thiamine monophosphate synthase 5 186 3.0E-55 T 13-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Astex_1713 1137e55f085bae7e58dedf5306f1aa9b 205 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 3 203 21.919 T 13-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Astex_1713 1137e55f085bae7e58dedf5306f1aa9b 205 Gene3D G3DSA:3.20.20.70 1 205 3.0E-59 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_0274 dde47169f595b94bc1b137d934c6720b 271 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 24 270 1.3E-84 T 13-10-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 Astex_0274 dde47169f595b94bc1b137d934c6720b 271 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 268 6.7E-15 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Astex_0274 dde47169f595b94bc1b137d934c6720b 271 Gene3D G3DSA:1.10.3720.10 71 270 2.1E-30 T 13-10-2018 IPR035906 MetI-like superfamily Astex_0274 dde47169f595b94bc1b137d934c6720b 271 SUPERFAMILY SSF161098 77 260 2.35E-32 T 13-10-2018 IPR035906 MetI-like superfamily Astex_2966 4040480a0e0307fa3a48f14b234694b3 817 SMART SM00954 333 443 1.2E-56 T 13-10-2018 IPR007685 RelA/SpoT GO:0015969 Astex_2966 4040480a0e0307fa3a48f14b234694b3 817 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 124 809 8.5E-198 T 13-10-2018 IPR004811 RelA/SpoT family GO:0015969 Astex_2966 4040480a0e0307fa3a48f14b234694b3 817 Pfam PF13328 HD domain 124 272 1.6E-44 T 13-10-2018 IPR003607 HD/PDEase domain Astex_2966 4040480a0e0307fa3a48f14b234694b3 817 Gene3D G3DSA:3.30.70.260 741 817 6.2E-9 T 13-10-2018 Astex_2966 4040480a0e0307fa3a48f14b234694b3 817 Pfam PF13291 ACT domain 741 814 4.2E-15 T 13-10-2018 IPR002912 ACT domain Astex_2966 4040480a0e0307fa3a48f14b234694b3 817 SUPERFAMILY SSF109604 104 288 1.54E-65 T 13-10-2018 Astex_2966 4040480a0e0307fa3a48f14b234694b3 817 Pfam PF04607 Region found in RelA / SpoT proteins 333 442 5.0E-34 T 13-10-2018 IPR007685 RelA/SpoT GO:0015969 Astex_2966 4040480a0e0307fa3a48f14b234694b3 817 SUPERFAMILY SSF81301 278 496 8.99E-53 T 13-10-2018 Astex_2966 4040480a0e0307fa3a48f14b234694b3 817 SUPERFAMILY SSF81271 479 551 1.31E-19 T 13-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 Astex_2966 4040480a0e0307fa3a48f14b234694b3 817 Gene3D G3DSA:1.10.3210.10 96 289 2.5E-72 T 13-10-2018 Astex_2966 4040480a0e0307fa3a48f14b234694b3 817 SUPERFAMILY SSF55021 739 815 1.08E-7 T 13-10-2018 Astex_2966 4040480a0e0307fa3a48f14b234694b3 817 SMART SM00471 139 251 6.2E-8 T 13-10-2018 IPR003607 HD/PDEase domain Astex_2966 4040480a0e0307fa3a48f14b234694b3 817 Pfam PF02824 TGS domain 493 551 7.6E-19 T 13-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 Astex_2966 4040480a0e0307fa3a48f14b234694b3 817 Gene3D G3DSA:3.10.20.30 486 558 1.6E-26 T 13-10-2018 IPR012675 Beta-grasp domain superfamily Astex_2966 4040480a0e0307fa3a48f14b234694b3 817 Gene3D G3DSA:3.30.460.10 293 423 1.1E-41 T 13-10-2018 Astex_2021 7f7087fede1368939fa262c1e0512f42 317 Gene3D G3DSA:1.10.287.110 2 130 2.3E-25 T 13-10-2018 IPR036869 Chaperone J-domain superfamily Astex_2021 7f7087fede1368939fa262c1e0512f42 317 Gene3D G3DSA:2.60.260.20 207 287 4.7E-22 T 13-10-2018 Astex_2021 7f7087fede1368939fa262c1e0512f42 317 Gene3D G3DSA:2.60.260.20 136 205 1.8E-17 T 13-10-2018 Astex_2021 7f7087fede1368939fa262c1e0512f42 317 SUPERFAMILY SSF46565 4 97 2.09E-25 T 13-10-2018 IPR036869 Chaperone J-domain superfamily Astex_2021 7f7087fede1368939fa262c1e0512f42 317 SUPERFAMILY SSF49493 136 214 3.53E-19 T 13-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 Astex_2021 7f7087fede1368939fa262c1e0512f42 317 SUPERFAMILY SSF49493 212 290 1.57E-15 T 13-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 Astex_2021 7f7087fede1368939fa262c1e0512f42 317 Pfam PF01556 DnaJ C terminal domain 142 287 9.8E-31 T 13-10-2018 IPR002939 Chaperone DnaJ, C-terminal Astex_2021 7f7087fede1368939fa262c1e0512f42 317 Pfam PF00226 DnaJ domain 4 66 6.4E-22 T 13-10-2018 IPR001623 DnaJ domain Astex_2021 7f7087fede1368939fa262c1e0512f42 317 ProSitePatterns PS00636 Nt-dnaJ domain signature. 46 65 - T 13-10-2018 IPR018253 DnaJ domain, conserved site Astex_2021 7f7087fede1368939fa262c1e0512f42 317 SMART SM00271 3 61 3.1E-23 T 13-10-2018 IPR001623 DnaJ domain Astex_2021 7f7087fede1368939fa262c1e0512f42 317 PRINTS PR00625 DnaJ domain signature 24 39 2.5E-17 T 13-10-2018 IPR001623 DnaJ domain Astex_2021 7f7087fede1368939fa262c1e0512f42 317 PRINTS PR00625 DnaJ domain signature 6 24 2.5E-17 T 13-10-2018 IPR001623 DnaJ domain Astex_2021 7f7087fede1368939fa262c1e0512f42 317 PRINTS PR00625 DnaJ domain signature 41 61 2.5E-17 T 13-10-2018 IPR001623 DnaJ domain Astex_3557 c7d6b90bd54f1d0933f2ef14c7244ef9 994 Gene3D G3DSA:2.170.130.10 42 185 3.8E-34 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_3557 c7d6b90bd54f1d0933f2ef14c7244ef9 994 Pfam PF07715 TonB-dependent Receptor Plug Domain 61 180 5.1E-19 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_3557 c7d6b90bd54f1d0933f2ef14c7244ef9 994 SUPERFAMILY SSF56935 40 994 4.4E-82 T 13-10-2018 Astex_3557 c7d6b90bd54f1d0933f2ef14c7244ef9 994 Pfam PF00593 TonB dependent receptor 426 991 1.3E-36 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_2527 1291727a3c98c426a0313113e65a4e23 126 Pfam PF11533 Protein of unknown function (DUF3225) 2 121 3.7E-48 T 13-10-2018 IPR024507 Protein of unknown function DUF3225 Astex_2527 1291727a3c98c426a0313113e65a4e23 126 Gene3D G3DSA:3.10.450.50 1 122 2.5E-43 T 13-10-2018 Astex_2527 1291727a3c98c426a0313113e65a4e23 126 SUPERFAMILY SSF54427 1 120 3.56E-32 T 13-10-2018 IPR032710 NTF2-like domain superfamily Astex_2904 69eb8d19ad7be62ecdc6a315918ee0b8 275 Gene3D G3DSA:2.120.10.30 2 275 2.8E-89 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like Astex_2904 69eb8d19ad7be62ecdc6a315918ee0b8 275 SUPERFAMILY SSF82171 6 273 2.22E-27 T 13-10-2018 Astex_2904 69eb8d19ad7be62ecdc6a315918ee0b8 275 Pfam PF07676 WD40-like Beta Propeller Repeat 260 273 0.23 T 13-10-2018 IPR011659 WD40-like Beta Propeller Astex_2904 69eb8d19ad7be62ecdc6a315918ee0b8 275 Pfam PF07676 WD40-like Beta Propeller Repeat 157 183 3.8E-4 T 13-10-2018 IPR011659 WD40-like Beta Propeller Astex_1783 3ed9e3df4efcb0cf0d3bea55cb429764 96 Gene3D G3DSA:3.30.2310.20 1 96 2.1E-22 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Astex_1783 3ed9e3df4efcb0cf0d3bea55cb429764 96 PIRSF PIRSF029218 1 96 5.5E-28 T 13-10-2018 IPR028344 Toxin-antitoxin system, toxin component ParE1/4 Astex_1783 3ed9e3df4efcb0cf0d3bea55cb429764 96 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 6 92 3.4E-16 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family Astex_2681 3068f28eb54c6f965e2f0f1495e8e8ba 296 Gene3D G3DSA:3.10.620.30 102 283 2.2E-32 T 13-10-2018 Astex_2681 3068f28eb54c6f965e2f0f1495e8e8ba 296 Pfam PF01841 Transglutaminase-like superfamily 133 243 1.6E-19 T 13-10-2018 IPR002931 Transglutaminase-like Astex_2681 3068f28eb54c6f965e2f0f1495e8e8ba 296 SUPERFAMILY SSF54001 13 271 7.73E-36 T 13-10-2018 IPR038765 Papain-like cysteine peptidase superfamily Astex_2681 3068f28eb54c6f965e2f0f1495e8e8ba 296 SMART SM00460 176 245 6.4E-18 T 13-10-2018 IPR002931 Transglutaminase-like Astex_2681 3068f28eb54c6f965e2f0f1495e8e8ba 296 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 10 87 3.7E-19 T 13-10-2018 IPR013589 Bacterial transglutaminase-like, N-terminal Astex_0593 fadb71f7a2f52515a6699bfce1fbb17f 339 Gene3D G3DSA:1.10.220.30 200 338 3.0E-42 T 13-10-2018 Astex_0593 fadb71f7a2f52515a6699bfce1fbb17f 339 Pfam PF14841 FliG middle domain 122 193 2.0E-23 T 13-10-2018 IPR032779 Flagellar motor switch protein FliG, middle domain Astex_0593 fadb71f7a2f52515a6699bfce1fbb17f 339 SUPERFAMILY SSF48029 121 329 4.05E-61 T 13-10-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical Astex_0593 fadb71f7a2f52515a6699bfce1fbb17f 339 Pfam PF01706 FliG C-terminal domain 222 328 4.0E-39 T 13-10-2018 IPR023087 Flagellar motor switch protein FliG, C-terminal Astex_0593 fadb71f7a2f52515a6699bfce1fbb17f 339 SUPERFAMILY SSF48029 11 119 1.11E-17 T 13-10-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical Astex_0593 fadb71f7a2f52515a6699bfce1fbb17f 339 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 8 335 2.1E-72 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 Astex_0593 fadb71f7a2f52515a6699bfce1fbb17f 339 Gene3D G3DSA:1.10.220.30 94 198 2.6E-23 T 13-10-2018 Astex_0593 fadb71f7a2f52515a6699bfce1fbb17f 339 PIRSF PIRSF003161 7 338 7.7E-110 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 Astex_0593 fadb71f7a2f52515a6699bfce1fbb17f 339 Gene3D G3DSA:1.10.220.30 5 91 2.4E-15 T 13-10-2018 Astex_0593 fadb71f7a2f52515a6699bfce1fbb17f 339 PRINTS PR00954 Flagellar motor switch protein FliG signature 230 250 2.7E-61 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 Astex_0593 fadb71f7a2f52515a6699bfce1fbb17f 339 PRINTS PR00954 Flagellar motor switch protein FliG signature 119 142 2.7E-61 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 Astex_0593 fadb71f7a2f52515a6699bfce1fbb17f 339 PRINTS PR00954 Flagellar motor switch protein FliG signature 276 302 2.7E-61 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 Astex_0593 fadb71f7a2f52515a6699bfce1fbb17f 339 PRINTS PR00954 Flagellar motor switch protein FliG signature 252 272 2.7E-61 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 Astex_0593 fadb71f7a2f52515a6699bfce1fbb17f 339 PRINTS PR00954 Flagellar motor switch protein FliG signature 12 28 2.7E-61 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 Astex_0593 fadb71f7a2f52515a6699bfce1fbb17f 339 PRINTS PR00954 Flagellar motor switch protein FliG signature 199 224 2.7E-61 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 Astex_0593 fadb71f7a2f52515a6699bfce1fbb17f 339 PRINTS PR00954 Flagellar motor switch protein FliG signature 40 66 2.7E-61 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 Astex_0593 fadb71f7a2f52515a6699bfce1fbb17f 339 Pfam PF14842 FliG N-terminal domain 12 112 1.7E-24 T 13-10-2018 IPR028263 Flagellar motor switch protein FliG, N-terminal domain Astex_0642 50951ff934b1a0216191d5e1c328f669 553 Gene3D G3DSA:2.115.10.20 49 362 1.6E-94 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Astex_0642 50951ff934b1a0216191d5e1c328f669 553 SUPERFAMILY SSF75005 50 362 1.57E-92 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Astex_0642 50951ff934b1a0216191d5e1c328f669 553 SUPERFAMILY SSF49899 372 552 3.96E-34 T 13-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily Astex_0642 50951ff934b1a0216191d5e1c328f669 553 Gene3D G3DSA:2.60.120.200 375 553 1.3E-38 T 13-10-2018 Astex_0642 50951ff934b1a0216191d5e1c328f669 553 Pfam PF04616 Glycosyl hydrolases family 43 50 341 3.6E-98 T 13-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 Astex_3534 7cfeb172c2f5f9f17190181d86cf85e9 406 SUPERFAMILY SSF103473 6 397 7.32E-68 T 13-10-2018 IPR036259 MFS transporter superfamily Astex_3534 7cfeb172c2f5f9f17190181d86cf85e9 406 Pfam PF07690 Major Facilitator Superfamily 16 349 4.1E-43 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Astex_3534 7cfeb172c2f5f9f17190181d86cf85e9 406 Gene3D G3DSA:1.20.1250.20 1 399 8.8E-66 T 13-10-2018 Astex_3579 a146e163512c73c68938f20c110a9a99 765 Gene3D G3DSA:3.30.2080.10 340 756 2.9E-221 T 13-10-2018 Astex_3579 a146e163512c73c68938f20c110a9a99 765 SUPERFAMILY SSF48208 305 748 1.11E-30 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 Astex_3579 a146e163512c73c68938f20c110a9a99 765 Gene3D G3DSA:1.20.1610.10 480 629 2.9E-221 T 13-10-2018 Astex_3579 a146e163512c73c68938f20c110a9a99 765 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 13 756 1.9E-152 T 13-10-2018 IPR005887 Alpha-1,2-mannosidase, putative Astex_3579 a146e163512c73c68938f20c110a9a99 765 Gene3D G3DSA:1.20.1050.60 385 479 2.9E-221 T 13-10-2018 Astex_3579 a146e163512c73c68938f20c110a9a99 765 Pfam PF07971 Glycosyl hydrolase family 92 282 752 1.0E-166 T 13-10-2018 IPR012939 Glycosyl hydrolase family 92 Astex_3579 a146e163512c73c68938f20c110a9a99 765 Gene3D G3DSA:2.70.98.10 41 384 2.9E-221 T 13-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 Astex_0671 78d8525ea2345e5ee098c254e8ce520e 723 Gene3D G3DSA:4.10.860.10 668 713 5.9E-10 T 13-10-2018 Astex_0671 78d8525ea2345e5ee098c254e8ce520e 723 SUPERFAMILY SSF52540 48 456 6.69E-131 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0671 78d8525ea2345e5ee098c254e8ce520e 723 Pfam PF02151 UvrB/uvrC motif 677 707 6.0E-7 T 13-10-2018 IPR001943 UVR domain GO:0005515 Astex_0671 78d8525ea2345e5ee098c254e8ce520e 723 Pfam PF12344 Ultra-violet resistance protein B 599 640 7.6E-22 T 13-10-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain Astex_0671 78d8525ea2345e5ee098c254e8ce520e 723 Pfam PF00271 Helicase conserved C-terminal domain 486 591 1.2E-17 T 13-10-2018 IPR001650 Helicase, C-terminal Astex_0671 78d8525ea2345e5ee098c254e8ce520e 723 SMART SM00490 507 593 7.7E-18 T 13-10-2018 IPR001650 Helicase, C-terminal Astex_0671 78d8525ea2345e5ee098c254e8ce520e 723 SUPERFAMILY SSF46600 664 708 3.92E-11 T 13-10-2018 IPR036876 UVR domain superfamily Astex_0671 78d8525ea2345e5ee098c254e8ce520e 723 Gene3D G3DSA:3.40.50.300 40 282 4.8E-78 T 13-10-2018 Astex_0671 78d8525ea2345e5ee098c254e8ce520e 723 Hamap MF_00204 UvrABC system protein B [uvrB]. 46 709 41.804 T 13-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 Astex_0671 78d8525ea2345e5ee098c254e8ce520e 723 SMART SM00487 52 469 8.4E-25 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Astex_0671 78d8525ea2345e5ee098c254e8ce520e 723 Pfam PF04851 Type III restriction enzyme, res subunit 59 181 4.1E-10 T 13-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 Astex_0671 78d8525ea2345e5ee098c254e8ce520e 723 Gene3D G3DSA:3.40.50.300 458 643 2.9E-47 T 13-10-2018 Astex_0671 78d8525ea2345e5ee098c254e8ce520e 723 SUPERFAMILY SSF52540 76 626 1.25E-35 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0671 78d8525ea2345e5ee098c254e8ce520e 723 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 48 707 0.0 T 13-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 Astex_0671 78d8525ea2345e5ee098c254e8ce520e 723 Gene3D G3DSA:3.40.50.300 321 457 6.8E-48 T 13-10-2018 Astex_2919 153e40022b038f920d45029358eb436d 423 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 26 55 - T 13-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 Astex_2919 153e40022b038f920d45029358eb436d 423 SUPERFAMILY SSF47005 116 162 7.19E-11 T 13-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 Astex_2919 153e40022b038f920d45029358eb436d 423 SUPERFAMILY SSF51230 2 96 2.88E-28 T 13-10-2018 IPR011053 Single hybrid motif Astex_2919 153e40022b038f920d45029358eb436d 423 TIGRFAM TIGR01349 PDHac_trf_mito: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase 4 422 1.1E-149 T 13-10-2018 IPR006257 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex GO:0004742|GO:0006090|GO:0045254 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-70268 Astex_2919 153e40022b038f920d45029358eb436d 423 Gene3D G3DSA:4.10.320.10 119 165 4.9E-16 T 13-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 Astex_2919 153e40022b038f920d45029358eb436d 423 SUPERFAMILY SSF52777 195 422 3.51E-83 T 13-10-2018 Astex_2919 153e40022b038f920d45029358eb436d 423 Gene3D G3DSA:2.40.50.100 1 102 2.7E-30 T 13-10-2018 Astex_2919 153e40022b038f920d45029358eb436d 423 Gene3D G3DSA:3.30.559.10 182 421 1.1E-91 T 13-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 Astex_2919 153e40022b038f920d45029358eb436d 423 Pfam PF00364 Biotin-requiring enzyme 3 76 1.9E-22 T 13-10-2018 IPR000089 Biotin/lipoyl attachment Astex_2919 153e40022b038f920d45029358eb436d 423 Pfam PF02817 e3 binding domain 123 158 4.2E-14 T 13-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 Astex_2919 153e40022b038f920d45029358eb436d 423 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 197 422 3.2E-83 T 13-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 Astex_1528 2199cb475ca6e9217bb5f000cf642d0e 320 Pfam PF02470 MlaD protein 39 116 6.7E-15 T 13-10-2018 IPR003399 Mce/MlaD Astex_1154 585cabf4e8dff002a35778c9472ab1ea 258 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 26 255 7.4E-49 T 13-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase Astex_1154 585cabf4e8dff002a35778c9472ab1ea 258 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 21 255 1.8E-59 T 13-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase Astex_1154 585cabf4e8dff002a35778c9472ab1ea 258 SUPERFAMILY SSF64438 6 256 2.01E-74 T 13-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic Astex_1154 585cabf4e8dff002a35778c9472ab1ea 258 Gene3D G3DSA:3.60.140.10 2 258 2.2E-78 T 13-10-2018 IPR038371 Multi-copper polyphenol oxidoreductase superfamily Astex_3532 b2102abd69c33cf01f26cf0f774a7e40 640 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 479 506 3.7E-19 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_3532 b2102abd69c33cf01f26cf0f774a7e40 640 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 398 427 3.7E-19 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_3532 b2102abd69c33cf01f26cf0f774a7e40 640 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 508 537 3.7E-19 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_3532 b2102abd69c33cf01f26cf0f774a7e40 640 SUPERFAMILY SSF58104 323 634 5.23E-55 T 13-10-2018 Astex_3532 b2102abd69c33cf01f26cf0f774a7e40 640 SMART SM00283 381 635 7.4E-38 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_3532 b2102abd69c33cf01f26cf0f774a7e40 640 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 446 594 2.4E-27 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_3532 b2102abd69c33cf01f26cf0f774a7e40 640 Gene3D G3DSA:1.10.287.950 357 636 2.5E-48 T 13-10-2018 Astex_3532 b2102abd69c33cf01f26cf0f774a7e40 640 Gene3D G3DSA:1.20.1480.50 252 351 9.3E-11 T 13-10-2018 Astex_3532 b2102abd69c33cf01f26cf0f774a7e40 640 SMART SM00304 292 345 0.0026 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Astex_1045 f7778d7a9bb807ba1b0c4106354ec091 390 Pfam PF03150 Di-haem cytochrome c peroxidase 61 214 1.1E-38 T 13-10-2018 IPR004852 Di-haem cytochrome c peroxidase GO:0016491|GO:0055114 Astex_1045 f7778d7a9bb807ba1b0c4106354ec091 390 SUPERFAMILY SSF46626 41 203 1.67E-40 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Astex_1045 f7778d7a9bb807ba1b0c4106354ec091 390 PIRSF PIRSF000294 40 385 2.0E-65 T 13-10-2018 IPR026259 Di-c-type haem protein, MauG/cytochrome c peroxidase GO:0016491|GO:0020037|GO:0055114 Astex_1045 f7778d7a9bb807ba1b0c4106354ec091 390 TIGRFAM TIGR04039 MXAN_0977_Heme2: di-heme enzyme, MXAN_0977 family 53 387 6.5E-147 T 13-10-2018 IPR023929 Di-heme enzyme, MXAN0977 Astex_1045 f7778d7a9bb807ba1b0c4106354ec091 390 Gene3D G3DSA:1.10.760.10 202 375 3.3E-81 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Astex_1045 f7778d7a9bb807ba1b0c4106354ec091 390 Gene3D G3DSA:1.10.760.10 57 201 3.3E-81 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Astex_1045 f7778d7a9bb807ba1b0c4106354ec091 390 SUPERFAMILY SSF46626 192 370 3.71E-30 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Astex_2542 a6b90783cbee82a4deecdb73073aea61 358 SUPERFAMILY SSF52440 6 104 1.18E-27 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily Astex_2542 a6b90783cbee82a4deecdb73073aea61 358 Pfam PF02222 ATP-grasp domain 116 284 5.6E-51 T 13-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type Astex_2542 a6b90783cbee82a4deecdb73073aea61 358 SUPERFAMILY SSF56059 106 304 3.54E-59 T 13-10-2018 Astex_2542 a6b90783cbee82a4deecdb73073aea61 358 Gene3D G3DSA:3.30.1490.20 111 184 8.3E-25 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 Astex_2542 a6b90783cbee82a4deecdb73073aea61 358 Gene3D G3DSA:3.40.50.20 2 110 1.2E-36 T 13-10-2018 Astex_2542 a6b90783cbee82a4deecdb73073aea61 358 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 9 354 1.7E-113 T 13-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 Astex_2542 a6b90783cbee82a4deecdb73073aea61 358 SUPERFAMILY SSF51246 310 354 1.02E-11 T 13-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 Astex_2542 a6b90783cbee82a4deecdb73073aea61 358 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 9 358 40.622 T 13-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 Astex_2542 a6b90783cbee82a4deecdb73073aea61 358 Gene3D G3DSA:3.30.470.20 185 358 3.2E-64 T 13-10-2018 Astex_2493 6cd6d8ce93a1a344afaefcea1018d5ea 280 Gene3D G3DSA:3.40.1190.20 13 279 5.4E-75 T 13-10-2018 IPR029056 Ribokinase-like Astex_2493 6cd6d8ce93a1a344afaefcea1018d5ea 280 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 11 278 19.058 T 13-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 Astex_2493 6cd6d8ce93a1a344afaefcea1018d5ea 280 SUPERFAMILY SSF53613 12 275 1.11E-65 T 13-10-2018 IPR029056 Ribokinase-like Astex_2493 6cd6d8ce93a1a344afaefcea1018d5ea 280 Pfam PF01256 Carbohydrate kinase 35 256 4.7E-55 T 13-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 Astex_2493 6cd6d8ce93a1a344afaefcea1018d5ea 280 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 27 273 1.4E-53 T 13-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 Astex_3153 5abbd6802770aced82a02dc7be2d8bc2 117 SUPERFAMILY SSF54593 1 116 8.99E-19 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Astex_3153 5abbd6802770aced82a02dc7be2d8bc2 117 Gene3D G3DSA:3.10.180.10 5 117 3.0E-15 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Astex_1924 626d86d59ec4ac3880179a9ad13ce8f1 774 Gene3D G3DSA:2.130.10.120 149 506 2.3E-139 T 13-10-2018 Astex_1924 626d86d59ec4ac3880179a9ad13ce8f1 774 Gene3D G3DSA:3.40.50.1820 99 731 2.3E-139 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1924 626d86d59ec4ac3880179a9ad13ce8f1 774 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 98 504 6.3E-59 T 13-10-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 Astex_1924 626d86d59ec4ac3880179a9ad13ce8f1 774 SUPERFAMILY SSF53474 515 753 5.75E-50 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1924 626d86d59ec4ac3880179a9ad13ce8f1 774 Pfam PF00326 Prolyl oligopeptidase family 570 772 2.3E-49 T 13-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 Astex_1924 626d86d59ec4ac3880179a9ad13ce8f1 774 SUPERFAMILY SSF50993 97 511 4.71E-48 T 13-10-2018 Astex_1924 626d86d59ec4ac3880179a9ad13ce8f1 774 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 601 620 1.2E-47 T 13-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 Astex_1924 626d86d59ec4ac3880179a9ad13ce8f1 774 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 686 701 1.2E-47 T 13-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 Astex_1924 626d86d59ec4ac3880179a9ad13ce8f1 774 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 705 727 1.2E-47 T 13-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 Astex_1924 626d86d59ec4ac3880179a9ad13ce8f1 774 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 573 597 1.2E-47 T 13-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 Astex_1924 626d86d59ec4ac3880179a9ad13ce8f1 774 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 631 651 1.2E-47 T 13-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 Astex_1924 626d86d59ec4ac3880179a9ad13ce8f1 774 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 546 564 1.2E-47 T 13-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 Astex_0979 ff59d2c7c2504908a684171fe46cba1c 180 PIRSF PIRSF033913 7 167 3.7E-29 T 13-10-2018 IPR024199 Uncharacterised conserved protein, DsbB-like Astex_0979 ff59d2c7c2504908a684171fe46cba1c 180 SUPERFAMILY SSF158442 12 161 8.24E-27 T 13-10-2018 IPR023380 DsbB-like superfamily Astex_0979 ff59d2c7c2504908a684171fe46cba1c 180 Pfam PF02600 Disulfide bond formation protein DsbB 9 161 3.1E-28 T 13-10-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 Astex_0979 ff59d2c7c2504908a684171fe46cba1c 180 Gene3D G3DSA:1.20.1550.10 3 175 1.8E-15 T 13-10-2018 IPR023380 DsbB-like superfamily Astex_1819 c28a823c1eb9914ba1682cad7ae4a4cb 383 Pfam PF01409 tRNA synthetases class II core domain (F) 118 367 1.7E-99 T 13-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 Astex_1819 c28a823c1eb9914ba1682cad7ae4a4cb 383 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 34 368 44.758 T 13-10-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 Astex_1819 c28a823c1eb9914ba1682cad7ae4a4cb 383 Gene3D G3DSA:3.30.930.10 34 370 6.4E-111 T 13-10-2018 Astex_1819 c28a823c1eb9914ba1682cad7ae4a4cb 383 SUPERFAMILY SSF46589 40 124 1.57E-18 T 13-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 Astex_1819 c28a823c1eb9914ba1682cad7ae4a4cb 383 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 66 367 2.6E-96 T 13-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 Astex_1819 c28a823c1eb9914ba1682cad7ae4a4cb 383 SUPERFAMILY SSF55681 118 369 3.32E-75 T 13-10-2018 Astex_1819 c28a823c1eb9914ba1682cad7ae4a4cb 383 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 45 113 3.6E-23 T 13-10-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 Astex_2698 a585efbffc08eae783e6c51393a5bb36 550 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 27 47 1.2E-6 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Astex_2698 a585efbffc08eae783e6c51393a5bb36 550 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 95 113 1.2E-6 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Astex_2698 a585efbffc08eae783e6c51393a5bb36 550 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 384 464 4.2E-29 T 13-10-2018 IPR032859 GTPase Der, C-terminal KH-domain-like Astex_2698 a585efbffc08eae783e6c51393a5bb36 550 Gene3D G3DSA:3.40.50.300 201 382 2.4E-47 T 13-10-2018 Astex_2698 a585efbffc08eae783e6c51393a5bb36 550 Gene3D G3DSA:3.30.300.20 384 466 7.5E-27 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta Astex_2698 a585efbffc08eae783e6c51393a5bb36 550 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 205 371 3.5E-27 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Astex_2698 a585efbffc08eae783e6c51393a5bb36 550 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 25 182 1.8E-26 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 Astex_2698 a585efbffc08eae783e6c51393a5bb36 550 SUPERFAMILY SSF52540 160 467 8.52E-62 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2698 a585efbffc08eae783e6c51393a5bb36 550 Gene3D G3DSA:3.40.50.300 27 187 8.8E-43 T 13-10-2018 Astex_2698 a585efbffc08eae783e6c51393a5bb36 550 Pfam PF01926 50S ribosome-binding GTPase 26 142 4.5E-27 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Astex_2698 a585efbffc08eae783e6c51393a5bb36 550 Pfam PF01926 50S ribosome-binding GTPase 208 326 2.9E-22 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Astex_2698 a585efbffc08eae783e6c51393a5bb36 550 SUPERFAMILY SSF52540 25 185 5.95E-43 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2698 a585efbffc08eae783e6c51393a5bb36 550 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 26 464 6.1E-162 T 13-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 Astex_2698 a585efbffc08eae783e6c51393a5bb36 550 Hamap MF_00195 GTPase Der [der]. 24 467 36.073 T 13-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 Astex_1755 e2ec8b3ddfe845e1c8b08ba1ddf31b1b 336 Pfam PF00326 Prolyl oligopeptidase family 162 324 1.1E-14 T 13-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 Astex_1755 e2ec8b3ddfe845e1c8b08ba1ddf31b1b 336 Gene3D G3DSA:3.40.50.1820 85 333 4.2E-59 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1755 e2ec8b3ddfe845e1c8b08ba1ddf31b1b 336 SUPERFAMILY SSF53474 88 326 3.8E-42 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1391 a0f3c76ce7d9081360399f056ca80896 93 Gene3D G3DSA:2.30.330.10 4 89 8.1E-18 T 13-10-2018 IPR036429 SpoA-like superfamily Astex_1391 a0f3c76ce7d9081360399f056ca80896 93 SUPERFAMILY SSF101801 11 83 9.81E-18 T 13-10-2018 IPR036429 SpoA-like superfamily Astex_1391 a0f3c76ce7d9081360399f056ca80896 93 PRINTS PR00956 Flagellar motor switch protein FliN signature 46 59 7.9E-13 T 13-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 Astex_1391 a0f3c76ce7d9081360399f056ca80896 93 PRINTS PR00956 Flagellar motor switch protein FliN signature 59 74 7.9E-13 T 13-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 Astex_1391 a0f3c76ce7d9081360399f056ca80896 93 PRINTS PR00956 Flagellar motor switch protein FliN signature 13 29 7.9E-13 T 13-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 Astex_1391 a0f3c76ce7d9081360399f056ca80896 93 PRINTS PR00956 Flagellar motor switch protein FliN signature 30 46 7.9E-13 T 13-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 Astex_1391 a0f3c76ce7d9081360399f056ca80896 93 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 13 83 1.0E-18 T 13-10-2018 IPR001543 Surface presentation of antigen (SpoA) Astex_3550 9d0bf07b5a0988a543a1d1363ac9c572 282 SUPERFAMILY SSF51182 5 266 4.68E-87 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily Astex_3550 9d0bf07b5a0988a543a1d1363ac9c572 282 Gene3D G3DSA:2.60.120.520 32 148 2.1E-98 T 13-10-2018 IPR027449 5-keto-4-deoxyuronate isomerase, N-terminal KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 Astex_3550 9d0bf07b5a0988a543a1d1363ac9c572 282 Pfam PF04962 KduI/IolB family 106 267 5.4E-31 T 13-10-2018 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 Astex_3550 9d0bf07b5a0988a543a1d1363ac9c572 282 Hamap MF_00687 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase [kduI]. 3 282 47.026 T 13-10-2018 IPR007045 5-keto 4-deoxyuronate isomerase GO:0008697|GO:0045490 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 Astex_3550 9d0bf07b5a0988a543a1d1363ac9c572 282 Gene3D G3DSA:2.60.120.10 15 267 2.1E-98 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Astex_3793 5418c91f73fc6da029b2f7f10a91d54f 210 Pfam PF12477 Sex factor F TraW protein N terminal 8 34 4.6E-6 T 13-10-2018 IPR025864 Type-F conjugative transfer system protein TraW N-terminal domain Astex_3793 5418c91f73fc6da029b2f7f10a91d54f 210 TIGRFAM TIGR02743 TraW: type-F conjugative transfer system protein TraW 8 208 2.0E-59 T 13-10-2018 IPR014114 Type-F conjugative transfer system protein TraW Astex_3312 488f5ae1ec0e13835bb226401659a3b3 1123 Pfam PF00593 TonB dependent receptor 520 1122 5.5E-31 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_3312 488f5ae1ec0e13835bb226401659a3b3 1123 Gene3D G3DSA:2.170.130.10 60 191 9.5E-13 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_3312 488f5ae1ec0e13835bb226401659a3b3 1123 Pfam PF07715 TonB-dependent Receptor Plug Domain 77 188 3.5E-11 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_3312 488f5ae1ec0e13835bb226401659a3b3 1123 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 59 1122 2.6E-172 T 13-10-2018 IPR010104 Bacterial TonB-dependent receptor Astex_3312 488f5ae1ec0e13835bb226401659a3b3 1123 SUPERFAMILY SSF56935 61 1123 3.66E-65 T 13-10-2018 Astex_1178 a91a4ae6ff67c34c9f3a86589741ff85 570 Gene3D G3DSA:3.40.50.410 415 563 7.0E-17 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Astex_1178 a91a4ae6ff67c34c9f3a86589741ff85 570 SUPERFAMILY SSF53300 143 560 3.05E-21 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Astex_1178 a91a4ae6ff67c34c9f3a86589741ff85 570 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 27 72 7.6E-7 T 13-10-2018 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal Astex_1178 a91a4ae6ff67c34c9f3a86589741ff85 570 Gene3D G3DSA:3.40.50.410 143 274 2.1E-7 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Astex_1178 a91a4ae6ff67c34c9f3a86589741ff85 570 Pfam PF00092 von Willebrand factor type A domain 478 555 3.7E-5 T 13-10-2018 IPR002035 von Willebrand factor, type A Astex_3218 1530a8a3013de7f33a28f030ab28c7d5 511 Gene3D G3DSA:3.40.50.1820 29 501 7.4E-138 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_3218 1530a8a3013de7f33a28f030ab28c7d5 511 ProSitePatterns PS00941 Carboxylesterases type-B signature 2. 99 109 - T 13-10-2018 IPR019819 Carboxylesterase type B, conserved site Astex_3218 1530a8a3013de7f33a28f030ab28c7d5 511 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 197 212 - T 13-10-2018 IPR019826 Carboxylesterase type B, active site Astex_3218 1530a8a3013de7f33a28f030ab28c7d5 511 SUPERFAMILY SSF53474 30 488 1.1E-114 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_3218 1530a8a3013de7f33a28f030ab28c7d5 511 PRINTS PR00878 Cholinesterase signature 122 151 7.9E-6 T 13-10-2018 IPR000997 Cholinesterase GO:0004104 Reactome: R-HSA-112311|Reactome: R-HSA-1483191|Reactome: R-HSA-422085 Astex_3218 1530a8a3013de7f33a28f030ab28c7d5 511 PRINTS PR00878 Cholinesterase signature 426 438 7.9E-6 T 13-10-2018 IPR000997 Cholinesterase GO:0004104 Reactome: R-HSA-112311|Reactome: R-HSA-1483191|Reactome: R-HSA-422085 Astex_3218 1530a8a3013de7f33a28f030ab28c7d5 511 Pfam PF00135 Carboxylesterase family 31 491 8.5E-107 T 13-10-2018 IPR002018 Carboxylesterase, type B Astex_0200 798fe9560eabba07a49a5650bd70c175 520 SMART SM00963 1 86 3.0E-27 T 13-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Astex_0200 798fe9560eabba07a49a5650bd70c175 520 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 446 30.979 T 13-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 Astex_0200 798fe9560eabba07a49a5650bd70c175 520 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 270 283 - T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Astex_0200 798fe9560eabba07a49a5650bd70c175 520 Gene3D G3DSA:1.10.260.30 311 448 5.9E-38 T 13-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 Astex_0200 798fe9560eabba07a49a5650bd70c175 520 SMART SM00962 101 297 2.1E-99 T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Astex_0200 798fe9560eabba07a49a5650bd70c175 520 SMART SM00382 100 248 6.6E-7 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_0200 798fe9560eabba07a49a5650bd70c175 520 SUPERFAMILY SSF47364 1 90 4.54E-23 T 13-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 Astex_0200 798fe9560eabba07a49a5650bd70c175 520 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 429 2.9E-165 T 13-10-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 Astex_0200 798fe9560eabba07a49a5650bd70c175 520 SUPERFAMILY SSF47446 299 431 2.49E-42 T 13-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 Astex_0200 798fe9560eabba07a49a5650bd70c175 520 Gene3D G3DSA:3.40.50.300 90 286 1.8E-107 T 13-10-2018 Astex_0200 798fe9560eabba07a49a5650bd70c175 520 SUPERFAMILY SSF52540 100 299 1.29E-46 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0200 798fe9560eabba07a49a5650bd70c175 520 Pfam PF00448 SRP54-type protein, GTPase domain 101 297 5.4E-65 T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Astex_0200 798fe9560eabba07a49a5650bd70c175 520 Pfam PF02978 Signal peptide binding domain 328 427 3.2E-29 T 13-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 Astex_0200 798fe9560eabba07a49a5650bd70c175 520 Gene3D G3DSA:1.20.120.140 5 307 1.8E-107 T 13-10-2018 Astex_0200 798fe9560eabba07a49a5650bd70c175 520 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 1.8E-17 T 13-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Astex_0536 03161f0fa51d10409284813a8c362d40 558 Gene3D G3DSA:3.40.50.300 341 553 1.8E-47 T 13-10-2018 Astex_0536 03161f0fa51d10409284813a8c362d40 558 Pfam PF02534 Type IV secretory system Conjugative DNA transfer 143 551 2.1E-79 T 13-10-2018 IPR003688 Type IV secretion system protein TraG/VirD4 GO:0009291|GO:0016020 Astex_0536 03161f0fa51d10409284813a8c362d40 558 SUPERFAMILY SSF52540 128 555 1.54E-49 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_3539 0b8c953c523f2be86655af0a90fed5df 284 Gene3D G3DSA:2.40.160.20 78 263 2.1E-7 T 13-10-2018 Astex_3539 0b8c953c523f2be86655af0a90fed5df 284 SUPERFAMILY SSF56925 89 251 1.1E-7 T 13-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel Astex_1870 2b880d7491845a0774b7892df120ba35 178 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 14 174 35.649 T 13-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 Astex_1870 2b880d7491845a0774b7892df120ba35 178 SUPERFAMILY SSF50324 3 173 1.57E-64 T 13-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 Astex_1870 2b880d7491845a0774b7892df120ba35 178 Gene3D G3DSA:3.90.80.10 1 176 3.3E-68 T 13-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 Astex_1870 2b880d7491845a0774b7892df120ba35 178 Pfam PF00719 Inorganic pyrophosphatase 18 172 7.7E-54 T 13-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 Astex_1879 e33db82f1cc02c1b32a22642b4af9015 290 Pfam PF04402 Protein of unknown function (DUF541) 48 214 9.3E-23 T 13-10-2018 IPR007497 Protein of unknown function DUF541 Astex_1879 e33db82f1cc02c1b32a22642b4af9015 290 Gene3D G3DSA:3.30.70.2970 57 172 7.1E-21 T 13-10-2018 Astex_1879 e33db82f1cc02c1b32a22642b4af9015 290 Gene3D G3DSA:3.30.110.170 48 214 7.1E-21 T 13-10-2018 Astex_1273 5099f2d1ca080a50ac2e2fb67a7ade31 376 SMART SM01005 246 372 4.3E-55 T 13-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Astex_1273 5099f2d1ca080a50ac2e2fb67a7ade31 376 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 43 53 - T 13-10-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Astex_1273 5099f2d1ca080a50ac2e2fb67a7ade31 376 Gene3D G3DSA:2.40.37.10 21 369 2.0E-113 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Astex_1273 5099f2d1ca080a50ac2e2fb67a7ade31 376 Pfam PF01168 Alanine racemase, N-terminal domain 20 235 4.5E-58 T 13-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Astex_1273 5099f2d1ca080a50ac2e2fb67a7ade31 376 Pfam PF00842 Alanine racemase, C-terminal domain 246 370 1.8E-36 T 13-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Astex_1273 5099f2d1ca080a50ac2e2fb67a7ade31 376 PRINTS PR00992 Alanine racemase signature 136 148 3.6E-44 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Astex_1273 5099f2d1ca080a50ac2e2fb67a7ade31 376 PRINTS PR00992 Alanine racemase signature 354 367 3.6E-44 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Astex_1273 5099f2d1ca080a50ac2e2fb67a7ade31 376 PRINTS PR00992 Alanine racemase signature 300 317 3.6E-44 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Astex_1273 5099f2d1ca080a50ac2e2fb67a7ade31 376 PRINTS PR00992 Alanine racemase signature 38 54 3.6E-44 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Astex_1273 5099f2d1ca080a50ac2e2fb67a7ade31 376 PRINTS PR00992 Alanine racemase signature 208 235 3.6E-44 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Astex_1273 5099f2d1ca080a50ac2e2fb67a7ade31 376 PRINTS PR00992 Alanine racemase signature 279 294 3.6E-44 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Astex_1273 5099f2d1ca080a50ac2e2fb67a7ade31 376 PRINTS PR00992 Alanine racemase signature 170 181 3.6E-44 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Astex_1273 5099f2d1ca080a50ac2e2fb67a7ade31 376 PRINTS PR00992 Alanine racemase signature 262 277 3.6E-44 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Astex_1273 5099f2d1ca080a50ac2e2fb67a7ade31 376 SUPERFAMILY SSF51419 20 247 1.16E-59 T 13-10-2018 IPR029066 PLP-binding barrel Astex_1273 5099f2d1ca080a50ac2e2fb67a7ade31 376 SUPERFAMILY SSF50621 239 372 6.28E-42 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Astex_1273 5099f2d1ca080a50ac2e2fb67a7ade31 376 TIGRFAM TIGR00492 alr: alanine racemase 19 372 4.1E-71 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Astex_1273 5099f2d1ca080a50ac2e2fb67a7ade31 376 Hamap MF_01201 Alanine racemase. 13 372 29.208 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Astex_1273 5099f2d1ca080a50ac2e2fb67a7ade31 376 Gene3D G3DSA:3.20.20.10 22 233 2.0E-113 T 13-10-2018 IPR029066 PLP-binding barrel Astex_2137 9eee7e696827bb1a1d8f257a25d3a756 248 Gene3D G3DSA:3.40.50.720 2 247 2.5E-75 T 13-10-2018 Astex_2137 9eee7e696827bb1a1d8f257a25d3a756 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Astex_2137 9eee7e696827bb1a1d8f257a25d3a756 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 3.8E-40 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2137 9eee7e696827bb1a1d8f257a25d3a756 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 3.8E-40 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2137 9eee7e696827bb1a1d8f257a25d3a756 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 3.8E-40 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2137 9eee7e696827bb1a1d8f257a25d3a756 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 3.8E-40 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2137 9eee7e696827bb1a1d8f257a25d3a756 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 3.8E-40 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2137 9eee7e696827bb1a1d8f257a25d3a756 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 3.8E-40 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2137 9eee7e696827bb1a1d8f257a25d3a756 248 SUPERFAMILY SSF51735 5 247 1.51E-71 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_2137 9eee7e696827bb1a1d8f257a25d3a756 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 245 2.3E-56 T 13-10-2018 Astex_2137 9eee7e696827bb1a1d8f257a25d3a756 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 2.9E-15 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2137 9eee7e696827bb1a1d8f257a25d3a756 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 2.9E-15 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2137 9eee7e696827bb1a1d8f257a25d3a756 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 2.9E-15 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0997 e78589bdbcf5c945e380331f4b157193 603 Pfam PF13193 AMP-binding enzyme C-terminal domain 485 555 2.9E-5 T 13-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain Astex_0997 e78589bdbcf5c945e380331f4b157193 603 ProSitePatterns PS00455 Putative AMP-binding domain signature. 202 213 - T 13-10-2018 IPR020845 AMP-binding, conserved site Astex_0997 e78589bdbcf5c945e380331f4b157193 603 Pfam PF00501 AMP-binding enzyme 40 471 5.3E-74 T 13-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Astex_0997 e78589bdbcf5c945e380331f4b157193 603 Gene3D G3DSA:3.40.50.12780 21 465 3.3E-79 T 13-10-2018 Astex_0997 e78589bdbcf5c945e380331f4b157193 603 Gene3D G3DSA:3.30.300.30 468 563 4.2E-8 T 13-10-2018 Astex_0997 e78589bdbcf5c945e380331f4b157193 603 SUPERFAMILY SSF56801 30 562 6.02E-105 T 13-10-2018 Astex_3827 56bef7558ba6407d8b3d75de7caf3da2 734 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 169 700 7.3E-123 T 13-10-2018 Astex_3827 56bef7558ba6407d8b3d75de7caf3da2 734 Gene3D G3DSA:2.70.150.20 194 305 9.3E-37 T 13-10-2018 Astex_3827 56bef7558ba6407d8b3d75de7caf3da2 734 Gene3D G3DSA:3.30.70.100 8 70 3.9E-15 T 13-10-2018 Astex_3827 56bef7558ba6407d8b3d75de7caf3da2 734 SUPERFAMILY SSF81665 153 686 1.57E-17 T 13-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 Astex_3827 56bef7558ba6407d8b3d75de7caf3da2 734 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 150 474 4.7E-97 T 13-10-2018 Astex_3827 56bef7558ba6407d8b3d75de7caf3da2 734 SUPERFAMILY SSF81653 203 300 7.19E-26 T 13-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 Astex_3827 56bef7558ba6407d8b3d75de7caf3da2 734 Gene3D G3DSA:3.40.50.1000 382 650 3.1E-83 T 13-10-2018 IPR023214 HAD superfamily Astex_3827 56bef7558ba6407d8b3d75de7caf3da2 734 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 598 617 1.3E-27 T 13-10-2018 Astex_3827 56bef7558ba6407d8b3d75de7caf3da2 734 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 547 557 1.3E-27 T 13-10-2018 Astex_3827 56bef7558ba6407d8b3d75de7caf3da2 734 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 250 264 1.3E-27 T 13-10-2018 Astex_3827 56bef7558ba6407d8b3d75de7caf3da2 734 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 621 633 1.3E-27 T 13-10-2018 Astex_3827 56bef7558ba6407d8b3d75de7caf3da2 734 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 401 415 1.3E-27 T 13-10-2018 Astex_3827 56bef7558ba6407d8b3d75de7caf3da2 734 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 525 536 1.3E-27 T 13-10-2018 Astex_3827 56bef7558ba6407d8b3d75de7caf3da2 734 Pfam PF00702 haloacid dehalogenase-like hydrolase 397 611 2.6E-41 T 13-10-2018 Astex_3827 56bef7558ba6407d8b3d75de7caf3da2 734 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 403 409 - T 13-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 Astex_3827 56bef7558ba6407d8b3d75de7caf3da2 734 Gene3D G3DSA:3.40.1110.10 412 532 3.1E-83 T 13-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 Astex_3827 56bef7558ba6407d8b3d75de7caf3da2 734 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 173 682 3.5E-85 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Astex_3827 56bef7558ba6407d8b3d75de7caf3da2 734 SUPERFAMILY SSF56784 400 698 4.4E-50 T 13-10-2018 IPR036412 HAD-like superfamily Astex_3827 56bef7558ba6407d8b3d75de7caf3da2 734 Pfam PF00122 E1-E2 ATPase 201 381 6.0E-54 T 13-10-2018 Astex_3827 56bef7558ba6407d8b3d75de7caf3da2 734 Pfam PF00403 Heavy-metal-associated domain 9 68 3.7E-14 T 13-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 Astex_3827 56bef7558ba6407d8b3d75de7caf3da2 734 SUPERFAMILY SSF55008 6 69 9.69E-16 T 13-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 Astex_3827 56bef7558ba6407d8b3d75de7caf3da2 734 PRINTS PR00941 Cadmium-transporting ATPase signature 266 282 2.0E-11 T 13-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 Astex_3827 56bef7558ba6407d8b3d75de7caf3da2 734 PRINTS PR00941 Cadmium-transporting ATPase signature 285 299 2.0E-11 T 13-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 Astex_3827 56bef7558ba6407d8b3d75de7caf3da2 734 PRINTS PR00941 Cadmium-transporting ATPase signature 20 41 2.0E-11 T 13-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 Astex_3827 56bef7558ba6407d8b3d75de7caf3da2 734 PRINTS PR00941 Cadmium-transporting ATPase signature 9 18 2.0E-11 T 13-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 Astex_3827 56bef7558ba6407d8b3d75de7caf3da2 734 PRINTS PR00941 Cadmium-transporting ATPase signature 185 205 2.0E-11 T 13-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 Astex_3827 56bef7558ba6407d8b3d75de7caf3da2 734 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 150 700 1.2E-179 T 13-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 Astex_3827 56bef7558ba6407d8b3d75de7caf3da2 734 ProSitePatterns PS01047 Heavy-metal-associated domain. 11 40 - T 13-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 Astex_3363 8e2762a309248ab5d80b6567e5101160 223 Pfam PF07077 Protein of unknown function (DUF1345) 40 213 7.8E-56 T 13-10-2018 IPR009781 Protein of unknown function DUF1345 Astex_1817 fd536dfd714d706a97e09f801615eeee 268 Pfam PF04536 TPM domain 42 180 4.3E-37 T 13-10-2018 IPR007621 TPM domain Astex_1817 fd536dfd714d706a97e09f801615eeee 268 Gene3D G3DSA:3.10.310.50 29 187 8.4E-51 T 13-10-2018 Astex_2541 9c7a29a98940440e2094f75241aba7d0 164 SUPERFAMILY SSF52255 7 160 1.19E-63 T 13-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 Astex_2541 9c7a29a98940440e2094f75241aba7d0 164 Gene3D G3DSA:3.40.50.7700 1 164 4.4E-71 T 13-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 Astex_2541 9c7a29a98940440e2094f75241aba7d0 164 PIRSF PIRSF001338 3 164 4.5E-65 T 13-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 Astex_2541 9c7a29a98940440e2094f75241aba7d0 164 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 8 162 33.132 T 13-10-2018 IPR033747 Class I PurE Astex_2541 9c7a29a98940440e2094f75241aba7d0 164 SMART SM01001 6 158 7.3E-101 T 13-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 Astex_2541 9c7a29a98940440e2094f75241aba7d0 164 Pfam PF00731 AIR carboxylase 7 155 1.3E-64 T 13-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 Astex_2541 9c7a29a98940440e2094f75241aba7d0 164 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 8 160 1.4E-64 T 13-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 Astex_1950 af42501723df0a395d6ba3b720baebba 209 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 39 48 - T 13-10-2018 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 Astex_1950 af42501723df0a395d6ba3b720baebba 209 Pfam PF01081 KDPG and KHG aldolase 8 199 1.9E-73 T 13-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 Astex_1950 af42501723df0a395d6ba3b720baebba 209 SUPERFAMILY SSF51569 5 206 1.01E-64 T 13-10-2018 Astex_1950 af42501723df0a395d6ba3b720baebba 209 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 9 206 5.1E-75 T 13-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 Astex_1950 af42501723df0a395d6ba3b720baebba 209 Gene3D G3DSA:3.20.20.70 2 207 2.0E-68 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_1950 af42501723df0a395d6ba3b720baebba 209 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 124 137 - T 13-10-2018 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 Astex_1555 6bee9b8d7a27ec9068a8dd44e24d862f 375 SUPERFAMILY SSF51735 140 319 6.73E-39 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_1555 6bee9b8d7a27ec9068a8dd44e24d862f 375 SUPERFAMILY SSF52283 4 171 1.53E-52 T 13-10-2018 Astex_1555 6bee9b8d7a27ec9068a8dd44e24d862f 375 SMART SM01002 149 315 1.9E-83 T 13-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain Astex_1555 6bee9b8d7a27ec9068a8dd44e24d862f 375 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 173 198 - T 13-10-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 Astex_1555 6bee9b8d7a27ec9068a8dd44e24d862f 375 Gene3D G3DSA:3.40.50.720 5 366 1.4E-141 T 13-10-2018 Astex_1555 6bee9b8d7a27ec9068a8dd44e24d862f 375 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 6 140 1.3E-45 T 13-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal Astex_1555 6bee9b8d7a27ec9068a8dd44e24d862f 375 SMART SM01003 6 140 3.8E-63 T 13-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal Astex_1555 6bee9b8d7a27ec9068a8dd44e24d862f 375 Gene3D G3DSA:3.40.50.720 140 322 1.4E-141 T 13-10-2018 Astex_1555 6bee9b8d7a27ec9068a8dd44e24d862f 375 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 144 370 2.1E-69 T 13-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain Astex_1908 017dd9be47e7caa00a711426ed32b9df 467 ProSitePatterns PS00217 Sugar transport proteins signature 2. 124 149 - T 13-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Astex_1908 017dd9be47e7caa00a711426ed32b9df 467 Gene3D G3DSA:1.20.1250.20 248 467 7.1E-68 T 13-10-2018 Astex_1908 017dd9be47e7caa00a711426ed32b9df 467 Pfam PF00083 Sugar (and other) transporter 8 464 6.3E-121 T 13-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 Astex_1908 017dd9be47e7caa00a711426ed32b9df 467 SUPERFAMILY SSF103473 8 461 1.31E-61 T 13-10-2018 IPR036259 MFS transporter superfamily Astex_1908 017dd9be47e7caa00a711426ed32b9df 467 PRINTS PR00171 Sugar transporter signature 382 394 6.7E-26 T 13-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 Astex_1908 017dd9be47e7caa00a711426ed32b9df 467 PRINTS PR00171 Sugar transporter signature 359 380 6.7E-26 T 13-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 Astex_1908 017dd9be47e7caa00a711426ed32b9df 467 PRINTS PR00171 Sugar transporter signature 274 284 6.7E-26 T 13-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 Astex_1908 017dd9be47e7caa00a711426ed32b9df 467 PRINTS PR00171 Sugar transporter signature 15 25 6.7E-26 T 13-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 Astex_1908 017dd9be47e7caa00a711426ed32b9df 467 PRINTS PR00171 Sugar transporter signature 119 138 6.7E-26 T 13-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 Astex_1908 017dd9be47e7caa00a711426ed32b9df 467 Gene3D G3DSA:1.20.1250.20 2 240 1.0E-59 T 13-10-2018 Astex_1908 017dd9be47e7caa00a711426ed32b9df 467 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 2 460 1.5E-123 T 13-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 Astex_0763 289c34ab93f4778e10081e6793be500e 163 Pfam PF13523 Acetyltransferase (GNAT) domain 9 147 2.4E-33 T 13-10-2018 Astex_0763 289c34ab93f4778e10081e6793be500e 163 SUPERFAMILY SSF55729 2 161 4.94E-34 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Astex_0763 289c34ab93f4778e10081e6793be500e 163 Gene3D G3DSA:3.40.630.30 1 163 7.9E-36 T 13-10-2018 Astex_1131 8d2ee319a7ee5fbdaa62c2a520d9a43c 323 SUPERFAMILY SSF53756 24 319 6.59E-39 T 13-10-2018 Astex_1131 8d2ee319a7ee5fbdaa62c2a520d9a43c 323 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 153 284 2.0E-16 T 13-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 Astex_1131 8d2ee319a7ee5fbdaa62c2a520d9a43c 323 Gene3D G3DSA:3.40.50.2000 147 322 8.0E-35 T 13-10-2018 Astex_2342 7c573be8425fa581c32d2d391fbea9a0 266 Pfam PF06629 MltA-interacting protein MipA 39 255 4.7E-26 T 13-10-2018 IPR010583 MltA-interacting MipA Astex_3244 10691425328afd393edf87c99da2bdc9 289 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 185 199 3.6E-5 T 13-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 Astex_3244 10691425328afd393edf87c99da2bdc9 289 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 230 250 3.6E-5 T 13-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 Astex_3244 10691425328afd393edf87c99da2bdc9 289 Gene3D G3DSA:3.40.50.150 91 287 1.4E-55 T 13-10-2018 Astex_3244 10691425328afd393edf87c99da2bdc9 289 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 189 195 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 Astex_3244 10691425328afd393edf87c99da2bdc9 289 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 8 285 41.573 T 13-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 Astex_3244 10691425328afd393edf87c99da2bdc9 289 Gene3D G3DSA:1.10.8.10 7 90 8.5E-18 T 13-10-2018 Astex_3244 10691425328afd393edf87c99da2bdc9 289 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 16 285 1.3E-55 T 13-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 Astex_3244 10691425328afd393edf87c99da2bdc9 289 Pfam PF05175 Methyltransferase small domain 110 197 1.3E-10 T 13-10-2018 IPR007848 Methyltransferase small domain GO:0008168 Astex_3244 10691425328afd393edf87c99da2bdc9 289 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 30 281 4.0E-77 T 13-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 Astex_3244 10691425328afd393edf87c99da2bdc9 289 SUPERFAMILY SSF53335 15 283 7.11E-51 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Astex_2847 fd2c27bb9955a4cea832bc526fcdd7f4 252 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 188 205 - T 13-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 Astex_2847 fd2c27bb9955a4cea832bc526fcdd7f4 252 Pfam PF01255 Putative undecaprenyl diphosphate synthase 22 242 3.5E-75 T 13-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 Astex_2847 fd2c27bb9955a4cea832bc526fcdd7f4 252 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 15 242 3.3E-81 T 13-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 Astex_2847 fd2c27bb9955a4cea832bc526fcdd7f4 252 SUPERFAMILY SSF64005 14 238 5.89E-77 T 13-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 Astex_2847 fd2c27bb9955a4cea832bc526fcdd7f4 252 Gene3D G3DSA:3.40.1180.10 9 244 5.4E-87 T 13-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 Astex_2847 fd2c27bb9955a4cea832bc526fcdd7f4 252 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 15 243 37.223 T 13-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 Astex_2090 ba202242d15e16c0505802cb02e6a5d0 537 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 258 271 - T 13-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_2090 ba202242d15e16c0505802cb02e6a5d0 537 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 40 517 35.734 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_2090 ba202242d15e16c0505802cb02e6a5d0 537 SUPERFAMILY SSF53697 18 533 2.22E-162 T 13-10-2018 Astex_2090 ba202242d15e16c0505802cb02e6a5d0 537 Gene3D G3DSA:3.40.50.10490 25 499 3.7E-184 T 13-10-2018 Astex_2090 ba202242d15e16c0505802cb02e6a5d0 537 Gene3D G3DSA:1.10.1390.10 500 537 1.5E-14 T 13-10-2018 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_2090 ba202242d15e16c0505802cb02e6a5d0 537 Gene3D G3DSA:3.40.50.10490 92 284 3.7E-184 T 13-10-2018 Astex_2090 ba202242d15e16c0505802cb02e6a5d0 537 PRINTS PR00662 Glucose-6-phosphate isomerase signature 476 490 5.6E-48 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_2090 ba202242d15e16c0505802cb02e6a5d0 537 PRINTS PR00662 Glucose-6-phosphate isomerase signature 490 503 5.6E-48 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_2090 ba202242d15e16c0505802cb02e6a5d0 537 PRINTS PR00662 Glucose-6-phosphate isomerase signature 144 163 5.6E-48 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_2090 ba202242d15e16c0505802cb02e6a5d0 537 PRINTS PR00662 Glucose-6-phosphate isomerase signature 254 272 5.6E-48 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_2090 ba202242d15e16c0505802cb02e6a5d0 537 PRINTS PR00662 Glucose-6-phosphate isomerase signature 331 352 5.6E-48 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_2090 ba202242d15e16c0505802cb02e6a5d0 537 PRINTS PR00662 Glucose-6-phosphate isomerase signature 458 476 5.6E-48 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_2090 ba202242d15e16c0505802cb02e6a5d0 537 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 490 507 - T 13-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_2090 ba202242d15e16c0505802cb02e6a5d0 537 Pfam PF00342 Phosphoglucose isomerase 46 532 2.0E-165 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_1300 c60d15dfd9563a9ccbd3626dd33670f2 393 SUPERFAMILY SSF53383 6 383 2.96E-90 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Astex_1300 c60d15dfd9563a9ccbd3626dd33670f2 393 Gene3D G3DSA:3.40.640.10 43 282 7.9E-114 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Astex_1300 c60d15dfd9563a9ccbd3626dd33670f2 393 Pfam PF00155 Aminotransferase class I and II 31 383 4.7E-62 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Astex_1300 c60d15dfd9563a9ccbd3626dd33670f2 393 Gene3D G3DSA:3.90.1150.10 18 383 7.9E-114 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Astex_3141 fbac7f1b6be8b90a887da2191d899a7f 454 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 289 451 1.4E-56 T 13-10-2018 IPR000160 GGDEF domain Astex_3141 fbac7f1b6be8b90a887da2191d899a7f 454 SMART SM00448 155 266 0.0071 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_3141 fbac7f1b6be8b90a887da2191d899a7f 454 SMART SM00448 3 116 6.3E-38 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_3141 fbac7f1b6be8b90a887da2191d899a7f 454 Pfam PF00990 Diguanylate cyclase, GGDEF domain 290 448 1.3E-50 T 13-10-2018 IPR000160 GGDEF domain Astex_3141 fbac7f1b6be8b90a887da2191d899a7f 454 Gene3D G3DSA:3.30.70.270 288 453 5.9E-60 T 13-10-2018 Astex_3141 fbac7f1b6be8b90a887da2191d899a7f 454 Pfam PF00072 Response regulator receiver domain 157 266 1.7E-5 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_3141 fbac7f1b6be8b90a887da2191d899a7f 454 Pfam PF00072 Response regulator receiver domain 5 116 2.6E-26 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_3141 fbac7f1b6be8b90a887da2191d899a7f 454 SUPERFAMILY SSF52172 2 136 9.53E-40 T 13-10-2018 IPR011006 CheY-like superfamily Astex_3141 fbac7f1b6be8b90a887da2191d899a7f 454 SUPERFAMILY SSF55073 295 451 8.63E-49 T 13-10-2018 IPR029787 Nucleotide cyclase Astex_3141 fbac7f1b6be8b90a887da2191d899a7f 454 SMART SM00267 280 452 3.3E-68 T 13-10-2018 IPR000160 GGDEF domain Astex_3141 fbac7f1b6be8b90a887da2191d899a7f 454 Gene3D G3DSA:3.40.50.12740 1 287 2.0E-91 T 13-10-2018 Astex_3141 fbac7f1b6be8b90a887da2191d899a7f 454 SUPERFAMILY SSF52172 150 283 1.85E-17 T 13-10-2018 IPR011006 CheY-like superfamily Astex_3477 873a5d79801af3ca8add997c3ae233b9 174 Gene3D G3DSA:1.10.1740.10 2 75 5.7E-8 T 13-10-2018 Astex_3477 873a5d79801af3ca8add997c3ae233b9 174 Pfam PF04542 Sigma-70 region 2 16 76 1.8E-9 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 Astex_3477 873a5d79801af3ca8add997c3ae233b9 174 Pfam PF08281 Sigma-70, region 4 118 164 5.2E-15 T 13-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Astex_3477 873a5d79801af3ca8add997c3ae233b9 174 SUPERFAMILY SSF88659 108 166 3.05E-13 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Astex_3477 873a5d79801af3ca8add997c3ae233b9 174 Gene3D G3DSA:1.10.10.10 76 171 9.0E-14 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_3477 873a5d79801af3ca8add997c3ae233b9 174 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 9 165 1.7E-20 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 Astex_3477 873a5d79801af3ca8add997c3ae233b9 174 SUPERFAMILY SSF88946 7 86 4.32E-12 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 Astex_2817 a1cedf8af455b58a31fb2b722aa2af6e 477 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 5 469 16.902 T 13-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 Astex_2817 a1cedf8af455b58a31fb2b722aa2af6e 477 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 9 436 2.0E-130 T 13-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 Astex_2817 a1cedf8af455b58a31fb2b722aa2af6e 477 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 69 94 7.1E-7 T 13-10-2018 Astex_2817 a1cedf8af455b58a31fb2b722aa2af6e 477 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 210 231 7.1E-7 T 13-10-2018 Astex_2817 a1cedf8af455b58a31fb2b722aa2af6e 477 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 302 314 7.1E-7 T 13-10-2018 Astex_2817 a1cedf8af455b58a31fb2b722aa2af6e 477 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 407 426 7.1E-7 T 13-10-2018 Astex_2817 a1cedf8af455b58a31fb2b722aa2af6e 477 Pfam PF00361 Proton-conducting membrane transporter 121 413 6.1E-71 T 13-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_3543 4b5e0d8ac462e41448e601d4f9a67d3d 368 Gene3D G3DSA:3.30.450.40 19 121 2.2E-6 T 13-10-2018 IPR029016 GAF-like domain superfamily Astex_3543 4b5e0d8ac462e41448e601d4f9a67d3d 368 Pfam PF07730 Histidine kinase 166 231 1.1E-11 T 13-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 Astex_3543 4b5e0d8ac462e41448e601d4f9a67d3d 368 Gene3D G3DSA:3.30.565.10 233 366 1.8E-22 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_3543 4b5e0d8ac462e41448e601d4f9a67d3d 368 SUPERFAMILY SSF55874 236 365 4.61E-11 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_3631 96ef4e313a3496153daf28299221360d 481 Pfam PF03572 Peptidase family S41 247 451 4.5E-11 T 13-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 Astex_3631 96ef4e313a3496153daf28299221360d 481 Gene3D G3DSA:3.90.226.10 232 478 1.7E-15 T 13-10-2018 Astex_3631 96ef4e313a3496153daf28299221360d 481 SUPERFAMILY SSF52096 198 472 2.98E-22 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Astex_3445 d8380fed1df88ccb29e00768efd7c86f 259 SMART SM00100 14 131 8.9E-5 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain Astex_3445 d8380fed1df88ccb29e00768efd7c86f 259 Pfam PF13545 Crp-like helix-turn-helix domain 151 220 4.6E-11 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 Astex_3445 d8380fed1df88ccb29e00768efd7c86f 259 Gene3D G3DSA:2.60.120.10 1 133 1.7E-18 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Astex_3445 d8380fed1df88ccb29e00768efd7c86f 259 SUPERFAMILY SSF46785 150 222 4.54E-7 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_3445 d8380fed1df88ccb29e00768efd7c86f 259 SUPERFAMILY SSF51206 8 143 2.75E-21 T 13-10-2018 IPR018490 Cyclic nucleotide-binding-like Astex_3445 d8380fed1df88ccb29e00768efd7c86f 259 Gene3D G3DSA:1.10.10.10 136 229 1.9E-24 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_3445 d8380fed1df88ccb29e00768efd7c86f 259 Pfam PF00027 Cyclic nucleotide-binding domain 33 118 4.9E-11 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain Astex_1006 a69beb49e5ce39d4f4af073d9eeff1ef 253 Pfam PF00462 Glutaredoxin 14 69 5.1E-8 T 13-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 Astex_1006 a69beb49e5ce39d4f4af073d9eeff1ef 253 Gene3D G3DSA:3.40.30.10 13 81 9.2E-12 T 13-10-2018 Astex_1006 a69beb49e5ce39d4f4af073d9eeff1ef 253 SUPERFAMILY SSF52833 16 82 2.67E-14 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Astex_1006 a69beb49e5ce39d4f4af073d9eeff1ef 253 Pfam PF07291 Methylamine utilisation protein MauE 116 242 2.2E-4 T 13-10-2018 IPR009908 Methylamine utilisation protein, MauE GO:0016021|GO:0030416 Astex_1006 a69beb49e5ce39d4f4af073d9eeff1ef 253 PRINTS PR00160 Glutaredoxin signature 53 66 2.1E-5 T 13-10-2018 IPR014025 Glutaredoxin subgroup Astex_1006 a69beb49e5ce39d4f4af073d9eeff1ef 253 PRINTS PR00160 Glutaredoxin signature 12 30 2.1E-5 T 13-10-2018 IPR014025 Glutaredoxin subgroup Astex_1006 a69beb49e5ce39d4f4af073d9eeff1ef 253 PRINTS PR00160 Glutaredoxin signature 67 80 2.1E-5 T 13-10-2018 IPR014025 Glutaredoxin subgroup Astex_1434 d90eb809b4291976872d439c8e6e113a 275 Pfam PF03448 MgtE intracellular N domain 184 249 8.5E-8 T 13-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain Astex_1434 d90eb809b4291976872d439c8e6e113a 275 SUPERFAMILY SSF158791 175 248 1.96E-7 T 13-10-2018 Astex_1063 060465e4c3252d59698c0bf495dce70c 345 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 52 2.5E-15 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Astex_1063 060465e4c3252d59698c0bf495dce70c 345 Pfam PF13377 Periplasmic binding protein-like domain 180 341 4.7E-39 T 13-10-2018 Astex_1063 060465e4c3252d59698c0bf495dce70c 345 Gene3D G3DSA:3.40.50.2300 171 337 1.4E-67 T 13-10-2018 Astex_1063 060465e4c3252d59698c0bf495dce70c 345 SMART SM00354 5 75 2.5E-20 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Astex_1063 060465e4c3252d59698c0bf495dce70c 345 Gene3D G3DSA:1.10.260.40 4 61 2.6E-19 T 13-10-2018 Astex_1063 060465e4c3252d59698c0bf495dce70c 345 SUPERFAMILY SSF47413 5 63 1.22E-16 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Astex_1063 060465e4c3252d59698c0bf495dce70c 345 Gene3D G3DSA:3.40.50.2300 92 333 1.4E-67 T 13-10-2018 Astex_1063 060465e4c3252d59698c0bf495dce70c 345 SUPERFAMILY SSF53822 79 344 2.17E-65 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Astex_2751 f978152025cd42caabbc57310842b9e9 301 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 26 281 8.4E-27 T 13-10-2018 IPR017039 Virulence factor BrkB Astex_2751 f978152025cd42caabbc57310842b9e9 301 PIRSF PIRSF035875 7 300 1.4E-70 T 13-10-2018 IPR017039 Virulence factor BrkB Astex_2751 f978152025cd42caabbc57310842b9e9 301 Pfam PF03631 Virulence factor BrkB 30 283 3.4E-58 T 13-10-2018 IPR017039 Virulence factor BrkB Astex_3214 16185440ba8bc19baf6382874ec3122d 1133 Gene3D G3DSA:2.170.130.10 47 177 2.4E-10 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_3214 16185440ba8bc19baf6382874ec3122d 1133 SUPERFAMILY SSF56935 48 1133 7.85E-51 T 13-10-2018 Astex_3214 16185440ba8bc19baf6382874ec3122d 1133 Pfam PF07715 TonB-dependent Receptor Plug Domain 65 168 2.0E-9 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_3214 16185440ba8bc19baf6382874ec3122d 1133 Pfam PF00593 TonB dependent receptor 514 1103 3.0E-19 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_3214 16185440ba8bc19baf6382874ec3122d 1133 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 48 1133 2.4E-133 T 13-10-2018 IPR010104 Bacterial TonB-dependent receptor Astex_0869 e67ef78d4ee63452e5fce645457d3924 162 ProSitePatterns PS00018 EF-hand calcium-binding domain. 32 44 - T 13-10-2018 IPR018247 EF-Hand 1, calcium-binding site Astex_0869 e67ef78d4ee63452e5fce645457d3924 162 ProSitePatterns PS00018 EF-hand calcium-binding domain. 132 144 - T 13-10-2018 IPR018247 EF-Hand 1, calcium-binding site Astex_0869 e67ef78d4ee63452e5fce645457d3924 162 Pfam PF13202 EF hand 32 46 4.6E-4 T 13-10-2018 IPR002048 EF-hand domain GO:0005509 Astex_0869 e67ef78d4ee63452e5fce645457d3924 162 SUPERFAMILY SSF47473 30 145 4.82E-13 T 13-10-2018 IPR011992 EF-hand domain pair Astex_0869 e67ef78d4ee63452e5fce645457d3924 162 Gene3D G3DSA:1.10.238.10 19 73 1.2E-5 T 13-10-2018 Astex_0869 e67ef78d4ee63452e5fce645457d3924 162 Gene3D G3DSA:1.10.238.10 88 153 2.3E-5 T 13-10-2018 Astex_0899 2291ad853691b59aef2f264c308f1990 125 PIRSF PIRSF025560 1 125 4.7E-25 T 13-10-2018 IPR008309 Uncharacterised conserved protein UCP025560 Astex_0899 2291ad853691b59aef2f264c308f1990 125 Pfam PF07027 Protein of unknown function (DUF1318) 33 125 1.9E-24 T 13-10-2018 IPR008309 Uncharacterised conserved protein UCP025560 Astex_2942 b4f9ffc34bdcd29bf10ab711ba36af8b 189 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 155 82.061 T 13-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 Astex_2942 b4f9ffc34bdcd29bf10ab711ba36af8b 189 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 142 8.6E-50 T 13-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 Astex_2942 b4f9ffc34bdcd29bf10ab711ba36af8b 189 Pfam PF03477 ATP cone domain 50 136 1.2E-16 T 13-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 Astex_3594 0fe6384d4822d5175eab5c91e6104b62 749 Pfam PF16153 Domain of unknown function (DUF4861) 481 741 5.2E-50 T 13-10-2018 IPR032342 Protein of unknown function DUF4861 Astex_3594 0fe6384d4822d5175eab5c91e6104b62 749 Pfam PF07470 Glycosyl Hydrolase Family 88 98 406 1.6E-63 T 13-10-2018 IPR010905 Glycosyl hydrolase, family 88 Astex_3594 0fe6384d4822d5175eab5c91e6104b62 749 SUPERFAMILY SSF48208 97 408 1.11E-38 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 Astex_3594 0fe6384d4822d5175eab5c91e6104b62 749 Gene3D G3DSA:1.50.10.10 74 409 1.2E-98 T 13-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 Astex_2790 23fe3ef034b71913e9a44e33fb9f1cd3 427 Gene3D G3DSA:3.40.47.10 1 270 7.3E-86 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 Astex_2790 23fe3ef034b71913e9a44e33fb9f1cd3 427 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 169 185 - T 13-10-2018 IPR018201 Beta-ketoacyl synthase, active site Astex_2790 23fe3ef034b71913e9a44e33fb9f1cd3 427 SMART SM00825 Beta-ketoacyl synthase 5 426 1.5E-12 T 13-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain Astex_2790 23fe3ef034b71913e9a44e33fb9f1cd3 427 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 270 383 1.3E-32 T 13-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal Astex_2790 23fe3ef034b71913e9a44e33fb9f1cd3 427 PIRSF PIRSF000447 1 427 4.2E-183 T 13-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 Astex_2790 23fe3ef034b71913e9a44e33fb9f1cd3 427 SUPERFAMILY SSF53901 3 267 2.34E-72 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 Astex_2790 23fe3ef034b71913e9a44e33fb9f1cd3 427 Gene3D G3DSA:3.40.47.10 276 427 9.7E-48 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 Astex_2790 23fe3ef034b71913e9a44e33fb9f1cd3 427 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 3 423 1.2E-185 T 13-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 Astex_2790 23fe3ef034b71913e9a44e33fb9f1cd3 427 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 262 2.4E-59 T 13-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal Astex_2790 23fe3ef034b71913e9a44e33fb9f1cd3 427 SUPERFAMILY SSF53901 232 426 3.32E-66 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 Astex_3075 0880428f306ecdea70a24d6e60f8294e 113 PIRSF PIRSF005894 3 113 5.2E-49 T 13-10-2018 IPR014434 Monothiol glutaredoxin GO:0015036 Reactome: R-HSA-1362409 Astex_3075 0880428f306ecdea70a24d6e60f8294e 113 SUPERFAMILY SSF52833 8 110 1.01E-34 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Astex_3075 0880428f306ecdea70a24d6e60f8294e 113 Pfam PF00462 Glutaredoxin 22 86 6.9E-18 T 13-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 Astex_3075 0880428f306ecdea70a24d6e60f8294e 113 Gene3D G3DSA:3.40.30.10 13 107 1.5E-34 T 13-10-2018 Astex_3075 0880428f306ecdea70a24d6e60f8294e 113 TIGRFAM TIGR00365 TIGR00365: monothiol glutaredoxin, Grx4 family 10 106 1.0E-43 T 13-10-2018 IPR004480 Monothiol glutaredoxin-related Astex_3023 dae20628ccdac13d17ca1c8d88ab2d07 138 SUPERFAMILY SSF54919 1 137 1.03E-49 T 13-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Astex_3023 dae20628ccdac13d17ca1c8d88ab2d07 138 SMART SM00562 1 138 5.6E-69 T 13-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Astex_3023 dae20628ccdac13d17ca1c8d88ab2d07 138 Gene3D G3DSA:3.30.70.141 1 138 3.2E-48 T 13-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Astex_3023 dae20628ccdac13d17ca1c8d88ab2d07 138 PRINTS PR01243 Nucleoside diphosphate kinase signature 68 85 3.9E-30 T 13-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Astex_3023 dae20628ccdac13d17ca1c8d88ab2d07 138 PRINTS PR01243 Nucleoside diphosphate kinase signature 112 131 3.9E-30 T 13-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Astex_3023 dae20628ccdac13d17ca1c8d88ab2d07 138 PRINTS PR01243 Nucleoside diphosphate kinase signature 4 26 3.9E-30 T 13-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Astex_3023 dae20628ccdac13d17ca1c8d88ab2d07 138 PRINTS PR01243 Nucleoside diphosphate kinase signature 89 105 3.9E-30 T 13-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Astex_3023 dae20628ccdac13d17ca1c8d88ab2d07 138 PRINTS PR01243 Nucleoside diphosphate kinase signature 48 67 3.9E-30 T 13-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Astex_3023 dae20628ccdac13d17ca1c8d88ab2d07 138 Pfam PF00334 Nucleoside diphosphate kinase 3 136 1.8E-48 T 13-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Astex_3023 dae20628ccdac13d17ca1c8d88ab2d07 138 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 1 136 32.312 T 13-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 Astex_0453 91280b336172123e592048833b4c34fa 479 PRINTS PR00084 Mannitol dehydrogenase signature 30 40 6.6E-14 T 13-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 Astex_0453 91280b336172123e592048833b4c34fa 479 PRINTS PR00084 Mannitol dehydrogenase signature 177 190 6.6E-14 T 13-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 Astex_0453 91280b336172123e592048833b4c34fa 479 PRINTS PR00084 Mannitol dehydrogenase signature 246 261 6.6E-14 T 13-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 Astex_0453 91280b336172123e592048833b4c34fa 479 PRINTS PR00084 Mannitol dehydrogenase signature 216 229 6.6E-14 T 13-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 Astex_0453 91280b336172123e592048833b4c34fa 479 Gene3D G3DSA:3.40.50.720 2 279 5.6E-96 T 13-10-2018 Astex_0453 91280b336172123e592048833b4c34fa 479 Gene3D G3DSA:1.10.1040.10 280 479 1.2E-58 T 13-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 Astex_0453 91280b336172123e592048833b4c34fa 479 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 29 186 2.9E-36 T 13-10-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 Astex_0453 91280b336172123e592048833b4c34fa 479 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 216 455 3.6E-63 T 13-10-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 Astex_0453 91280b336172123e592048833b4c34fa 479 SUPERFAMILY SSF51735 4 280 4.33E-87 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_0453 91280b336172123e592048833b4c34fa 479 SUPERFAMILY SSF48179 281 474 4.76E-49 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Astex_0325 d299a1221cd79648db6fa8a53b812663 178 Gene3D G3DSA:3.30.70.940 21 171 9.3E-9 T 13-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 Astex_0325 d299a1221cd79648db6fa8a53b812663 178 Pfam PF02357 Transcription termination factor nusG 22 80 6.4E-6 T 13-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 Astex_0325 d299a1221cd79648db6fa8a53b812663 178 SUPERFAMILY SSF82679 22 82 1.96E-7 T 13-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 Astex_3056 7289157fcd9db428d59924a152a853aa 293 SUPERFAMILY SSF52540 4 237 1.61E-29 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_3056 7289157fcd9db428d59924a152a853aa 293 Gene3D G3DSA:3.40.50.300 1 280 3.3E-70 T 13-10-2018 Astex_3056 7289157fcd9db428d59924a152a853aa 293 Pfam PF09140 ATPase MipZ 6 266 6.9E-103 T 13-10-2018 IPR015223 ATPase MipZ Astex_3599 6cfbbcf213f68315e92b2f7bcf37a525 157 SUPERFAMILY SSF54593 3 155 2.95E-44 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Astex_3599 6cfbbcf213f68315e92b2f7bcf37a525 157 Gene3D G3DSA:3.10.180.70 1 157 1.2E-59 T 13-10-2018 Astex_3599 6cfbbcf213f68315e92b2f7bcf37a525 157 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 3 118 1.1E-46 T 13-10-2018 IPR028973 PhnB-like Astex_3599 6cfbbcf213f68315e92b2f7bcf37a525 157 PIRSF PIRSF021700 1 157 1.1E-64 T 13-10-2018 IPR009725 Predicted 3-demethylubiquinone-9 3-methyltransferase Astex_2446 6cc72139fb4159e7e5324327bc5f184a 283 Pfam PF13471 Transglutaminase-like superfamily 168 281 1.9E-23 T 13-10-2018 IPR032708 Microcin J25-processing protein McjB, C-terminal Astex_2619 d729e15b9e9d534ae5ac03989cdd4cdc 178 Pfam PF04442 Cytochrome c oxidase assembly protein CtaG/Cox11 28 171 2.5E-50 T 13-10-2018 IPR007533 Cytochrome c oxidase assembly protein CtaG/Cox11 GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_2619 d729e15b9e9d534ae5ac03989cdd4cdc 178 SUPERFAMILY SSF110111 51 175 1.28E-41 T 13-10-2018 IPR023471 Cytochrome c oxidase assembly protein CtaG/Cox11, domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_2619 d729e15b9e9d534ae5ac03989cdd4cdc 178 Hamap MF_00155 Cytochrome c oxidase assembly protein CtaG [ctaG]. 1 178 36.127 T 13-10-2018 IPR007533 Cytochrome c oxidase assembly protein CtaG/Cox11 GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_2619 d729e15b9e9d534ae5ac03989cdd4cdc 178 PIRSF PIRSF005413 1 178 7.8E-62 T 13-10-2018 IPR007533 Cytochrome c oxidase assembly protein CtaG/Cox11 GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_2619 d729e15b9e9d534ae5ac03989cdd4cdc 178 Gene3D G3DSA:2.60.370.10 48 178 9.7E-45 T 13-10-2018 IPR023471 Cytochrome c oxidase assembly protein CtaG/Cox11, domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_1350 f9748ea8ac21691bddf7003ba43a83da 299 Pfam PF00902 Sec-independent protein translocase protein (TatC) 26 273 1.1E-67 T 13-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 Astex_1350 f9748ea8ac21691bddf7003ba43a83da 299 ProSitePatterns PS01218 TatC family signature. 206 225 - T 13-10-2018 IPR019820 Sec-independent periplasmic protein translocase, conserved site Astex_1350 f9748ea8ac21691bddf7003ba43a83da 299 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 14 292 16.799 T 13-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 Astex_1350 f9748ea8ac21691bddf7003ba43a83da 299 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 132 150 1.6E-40 T 13-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 Astex_1350 f9748ea8ac21691bddf7003ba43a83da 299 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 23 50 1.6E-40 T 13-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 Astex_1350 f9748ea8ac21691bddf7003ba43a83da 299 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 150 176 1.6E-40 T 13-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 Astex_1350 f9748ea8ac21691bddf7003ba43a83da 299 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 206 234 1.6E-40 T 13-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 Astex_1350 f9748ea8ac21691bddf7003ba43a83da 299 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 24 278 1.2E-56 T 13-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 Astex_2805 972753a740bd75f3aa895c2dbd7283fd 419 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 147 419 2.5E-124 T 13-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2805 972753a740bd75f3aa895c2dbd7283fd 419 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 70 81 - T 13-10-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2805 972753a740bd75f3aa895c2dbd7283fd 419 SUPERFAMILY SSF56762 43 419 7.2E-141 T 13-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2805 972753a740bd75f3aa895c2dbd7283fd 419 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 33 419 1.2E-180 T 13-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2805 972753a740bd75f3aa895c2dbd7283fd 419 Gene3D G3DSA:1.10.645.20 32 419 4.0E-175 T 13-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2805 972753a740bd75f3aa895c2dbd7283fd 419 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 22 419 48.614 T 13-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_3591 f428097d5b40da5245df65cb91690a6d 955 SUPERFAMILY SSF63411 746 952 7.02E-34 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 Astex_3591 f428097d5b40da5245df65cb91690a6d 955 Gene3D G3DSA:3.30.830.10 745 939 3.5E-34 T 13-10-2018 Astex_3591 f428097d5b40da5245df65cb91690a6d 955 SUPERFAMILY SSF63411 521 723 2.79E-42 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 Astex_3591 f428097d5b40da5245df65cb91690a6d 955 SUPERFAMILY SSF63411 278 453 6.67E-21 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 Astex_3591 f428097d5b40da5245df65cb91690a6d 955 Gene3D G3DSA:3.30.830.10 44 265 1.3E-60 T 13-10-2018 Astex_3591 f428097d5b40da5245df65cb91690a6d 955 Gene3D G3DSA:3.30.830.10 273 467 2.4E-26 T 13-10-2018 Astex_3591 f428097d5b40da5245df65cb91690a6d 955 SUPERFAMILY SSF63411 45 269 3.32E-48 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 Astex_3591 f428097d5b40da5245df65cb91690a6d 955 Gene3D G3DSA:3.30.830.10 527 734 3.5E-40 T 13-10-2018 Astex_3591 f428097d5b40da5245df65cb91690a6d 955 Pfam PF00675 Insulinase (Peptidase family M16) 540 681 9.0E-11 T 13-10-2018 IPR011765 Peptidase M16, N-terminal Astex_3591 f428097d5b40da5245df65cb91690a6d 955 Pfam PF00675 Insulinase (Peptidase family M16) 57 146 5.7E-14 T 13-10-2018 IPR011765 Peptidase M16, N-terminal Astex_3591 f428097d5b40da5245df65cb91690a6d 955 Pfam PF05193 Peptidase M16 inactive domain 217 392 2.3E-23 T 13-10-2018 IPR007863 Peptidase M16, C-terminal Astex_3591 f428097d5b40da5245df65cb91690a6d 955 Pfam PF05193 Peptidase M16 inactive domain 688 865 7.3E-15 T 13-10-2018 IPR007863 Peptidase M16, C-terminal Astex_3049 c11a2843cc83e89156904fc404fa3184 122 SUPERFAMILY SSF48295 25 74 1.46E-9 T 13-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 Astex_3049 c11a2843cc83e89156904fc404fa3184 122 Pfam PF01527 Transposase 26 75 6.0E-13 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 Astex_2196 c11a2843cc83e89156904fc404fa3184 122 SUPERFAMILY SSF48295 25 74 1.46E-9 T 13-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 Astex_2196 c11a2843cc83e89156904fc404fa3184 122 Pfam PF01527 Transposase 26 75 6.0E-13 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 Astex_1810 a36b7205527342a6b5332a54d24911c6 308 SUPERFAMILY SSF53474 54 178 1.0E-12 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1810 a36b7205527342a6b5332a54d24911c6 308 Pfam PF05990 Alpha/beta hydrolase of unknown function (DUF900) 57 202 8.1E-14 T 13-10-2018 IPR010297 Protein of unknown function DUF900, hydrolase-like Astex_2462 7e88bb8682859e56a4e34c44bfd71eed 369 SUPERFAMILY SSF51197 52 322 5.04E-39 T 13-10-2018 Astex_2462 7e88bb8682859e56a4e34c44bfd71eed 369 Gene3D G3DSA:3.60.130.10 37 326 3.9E-41 T 13-10-2018 Astex_2462 7e88bb8682859e56a4e34c44bfd71eed 369 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 70 317 4.4E-27 T 13-10-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 Astex_2898 fe90dfbdc8416979acd9f2d9012b2635 642 Gene3D G3DSA:1.10.4030.30 227 359 1.0E-6 T 13-10-2018 Astex_2898 fe90dfbdc8416979acd9f2d9012b2635 642 SUPERFAMILY SSF54534 272 355 1.44E-6 T 13-10-2018 Astex_2898 fe90dfbdc8416979acd9f2d9012b2635 642 SUPERFAMILY SSF109998 42 242 4.71E-9 T 13-10-2018 IPR027304 Trigger factor/SurA domain superfamily Astex_2898 fe90dfbdc8416979acd9f2d9012b2635 642 Gene3D G3DSA:3.10.50.40 269 355 1.0E-6 T 13-10-2018 Astex_2898 fe90dfbdc8416979acd9f2d9012b2635 642 Pfam PF13145 PPIC-type PPIASE domain 249 366 2.7E-23 T 13-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 Astex_2898 fe90dfbdc8416979acd9f2d9012b2635 642 Pfam PF13145 PPIC-type PPIASE domain 372 477 2.8E-6 T 13-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 Astex_2898 fe90dfbdc8416979acd9f2d9012b2635 642 Pfam PF13624 SurA N-terminal domain 1 165 2.3E-31 T 13-10-2018 Astex_2581 5fd689990f3f5ea4a360e70d100cdf4d 946 Pfam PF07944 Beta-L-arabinofuranosidase, GH127 354 846 2.2E-115 T 13-10-2018 IPR012878 Beta-L-arabinofuranosidase, GH127 Astex_2581 5fd689990f3f5ea4a360e70d100cdf4d 946 SUPERFAMILY SSF49785 53 180 2.64E-6 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_2581 5fd689990f3f5ea4a360e70d100cdf4d 946 Gene3D G3DSA:2.60.40.10 203 294 2.1E-6 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_2581 5fd689990f3f5ea4a360e70d100cdf4d 946 Pfam PF00754 F5/8 type C domain 61 180 9.2E-7 T 13-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain Astex_2581 5fd689990f3f5ea4a360e70d100cdf4d 946 Gene3D G3DSA:2.60.120.260 51 196 8.2E-32 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_2581 5fd689990f3f5ea4a360e70d100cdf4d 946 SUPERFAMILY SSF48208 442 671 6.46E-14 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 Astex_1031 ade8912ac35c33d2449c2406371d194a 401 SUPERFAMILY SSF52540 3 319 4.34E-44 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1031 ade8912ac35c33d2449c2406371d194a 401 Gene3D G3DSA:3.40.50.300 1 229 7.6E-72 T 13-10-2018 Astex_1031 ade8912ac35c33d2449c2406371d194a 401 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 256 371 6.0E-28 T 13-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal Astex_1031 ade8912ac35c33d2449c2406371d194a 401 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 5 210 4.3E-56 T 13-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain Astex_1031 ade8912ac35c33d2449c2406371d194a 401 SMART SM00833 256 371 1.3E-48 T 13-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal Astex_3602 a1ae19c95c9c6f119947f7456b3fd885 1121 Pfam PF14614 Domain of unknown function (DUF4450) 94 283 4.8E-31 T 13-10-2018 IPR028028 Protein of unknown function DUF4450 Astex_3602 a1ae19c95c9c6f119947f7456b3fd885 1121 Gene3D G3DSA:1.50.10.10 381 695 2.8E-21 T 13-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 Astex_3602 a1ae19c95c9c6f119947f7456b3fd885 1121 SUPERFAMILY SSF48208 323 752 1.02E-32 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 Astex_2168 4c1c22521f5c1293e5fa77495413fd09 506 Gene3D G3DSA:3.30.420.40 214 269 8.0E-6 T 13-10-2018 Astex_2168 4c1c22521f5c1293e5fa77495413fd09 506 Gene3D G3DSA:3.30.420.40 38 132 2.3E-22 T 13-10-2018 Astex_2168 4c1c22521f5c1293e5fa77495413fd09 506 Gene3D G3DSA:3.30.420.40 270 506 6.5E-55 T 13-10-2018 Astex_2168 4c1c22521f5c1293e5fa77495413fd09 506 SUPERFAMILY SSF53067 45 277 2.41E-14 T 13-10-2018 Astex_2168 4c1c22521f5c1293e5fa77495413fd09 506 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 44 277 8.1E-13 T 13-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 Astex_3621 5b19800e43c6b5515943f035e6aeb112 253 Pfam PF07729 FCD domain 113 236 3.8E-14 T 13-10-2018 IPR011711 GntR, C-terminal Astex_3621 5b19800e43c6b5515943f035e6aeb112 253 SMART SM00895 113 237 5.7E-12 T 13-10-2018 IPR011711 GntR, C-terminal Astex_3621 5b19800e43c6b5515943f035e6aeb112 253 SMART SM00345 23 82 1.6E-19 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Astex_3621 5b19800e43c6b5515943f035e6aeb112 253 SUPERFAMILY SSF48008 112 241 1.6E-17 T 13-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal Astex_3621 5b19800e43c6b5515943f035e6aeb112 253 Gene3D G3DSA:1.20.120.530 109 245 3.3E-17 T 13-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal Astex_3621 5b19800e43c6b5515943f035e6aeb112 253 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 56 72 1.2E-8 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Astex_3621 5b19800e43c6b5515943f035e6aeb112 253 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 56 1.2E-8 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Astex_3621 5b19800e43c6b5515943f035e6aeb112 253 Gene3D G3DSA:1.10.10.10 15 85 7.7E-19 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_3621 5b19800e43c6b5515943f035e6aeb112 253 SUPERFAMILY SSF46785 14 86 1.36E-18 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_3621 5b19800e43c6b5515943f035e6aeb112 253 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 82 1.2E-19 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Astex_0269 7f693d6699d71c1f4f90f3a0c91fc683 313 Pfam PF00448 SRP54-type protein, GTPase domain 107 306 1.3E-70 T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Astex_0269 7f693d6699d71c1f4f90f3a0c91fc683 313 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 36 307 54.367 T 13-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 Astex_0269 7f693d6699d71c1f4f90f3a0c91fc683 313 SUPERFAMILY SSF47364 7 73 2.88E-13 T 13-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 Astex_0269 7f693d6699d71c1f4f90f3a0c91fc683 313 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 280 293 - T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Astex_0269 7f693d6699d71c1f4f90f3a0c91fc683 313 SMART SM00962 106 307 6.9E-100 T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Astex_0269 7f693d6699d71c1f4f90f3a0c91fc683 313 SMART SM00963 12 91 2.5E-4 T 13-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 Astex_0269 7f693d6699d71c1f4f90f3a0c91fc683 313 SMART SM00382 105 252 3.6E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_0269 7f693d6699d71c1f4f90f3a0c91fc683 313 SUPERFAMILY SSF52540 104 305 1.13E-47 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0269 7f693d6699d71c1f4f90f3a0c91fc683 313 Gene3D G3DSA:3.40.50.300 106 295 2.4E-102 T 13-10-2018 Astex_0269 7f693d6699d71c1f4f90f3a0c91fc683 313 Gene3D G3DSA:1.20.120.140 9 304 2.4E-102 T 13-10-2018 Astex_0269 7f693d6699d71c1f4f90f3a0c91fc683 313 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 39 305 3.6E-91 T 13-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 Astex_0936 86c2e37f96c632a25e059051ff31a4b0 528 SMART SM00642 53 412 1.9E-83 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Astex_0936 86c2e37f96c632a25e059051ff31a4b0 528 Pfam PF11941 Domain of unknown function (DUF3459) 429 496 5.6E-5 T 13-10-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) Astex_0936 86c2e37f96c632a25e059051ff31a4b0 528 SUPERFAMILY SSF51445 44 443 1.73E-101 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_0936 86c2e37f96c632a25e059051ff31a4b0 528 Gene3D G3DSA:3.90.400.10 143 205 7.1E-126 T 13-10-2018 Astex_0936 86c2e37f96c632a25e059051ff31a4b0 528 Gene3D G3DSA:3.20.20.80 45 439 7.1E-126 T 13-10-2018 Astex_0936 86c2e37f96c632a25e059051ff31a4b0 528 SUPERFAMILY SSF51011 446 522 2.67E-8 T 13-10-2018 Astex_0936 86c2e37f96c632a25e059051ff31a4b0 528 Pfam PF00128 Alpha amylase, catalytic domain 68 376 3.3E-61 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 Astex_2303 70552a5634a94416687dee836bdbc85d 206 SMART SM00947 28 191 4.8E-64 T 13-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Astex_2303 70552a5634a94416687dee836bdbc85d 206 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 40 47 - T 13-10-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Astex_2303 70552a5634a94416687dee836bdbc85d 206 SUPERFAMILY SSF53056 2 197 1.05E-72 T 13-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 Astex_2303 70552a5634a94416687dee836bdbc85d 206 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 80 100 - T 13-10-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Astex_2303 70552a5634a94416687dee836bdbc85d 206 Gene3D G3DSA:3.40.1050.10 1 206 2.7E-81 T 13-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 Astex_2303 70552a5634a94416687dee836bdbc85d 206 Pfam PF00484 Carbonic anhydrase 35 187 1.2E-52 T 13-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 Astex_2283 fb8e30c721bad1d420af1092d1e13c95 389 SUPERFAMILY SSF53756 50 384 2.3E-30 T 13-10-2018 Astex_2283 fb8e30c721bad1d420af1092d1e13c95 389 Gene3D G3DSA:3.40.50.2000 199 385 7.5E-31 T 13-10-2018 Astex_2283 fb8e30c721bad1d420af1092d1e13c95 389 Pfam PF00534 Glycosyl transferases group 1 234 370 1.3E-11 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 Astex_0231 490a02100a348d27d8c0cbd70a5f354f 160 SUPERFAMILY SSF55961 5 159 1.13E-23 T 13-10-2018 Astex_0231 490a02100a348d27d8c0cbd70a5f354f 160 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 18 157 2.0E-12 T 13-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like Astex_0231 490a02100a348d27d8c0cbd70a5f354f 160 Gene3D G3DSA:3.30.530.20 1 160 8.4E-35 T 13-10-2018 IPR023393 START-like domain superfamily Astex_1628 d88ab7d24c1a99476f816721181e9d18 236 Gene3D G3DSA:3.30.1600.10 19 158 5.0E-70 T 13-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily Astex_1628 d88ab7d24c1a99476f816721181e9d18 236 Gene3D G3DSA:3.40.50.1220 5 228 5.0E-70 T 13-10-2018 Astex_1628 d88ab7d24c1a99476f816721181e9d18 236 SUPERFAMILY SSF52467 4 229 1.31E-63 T 13-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily Astex_1628 d88ab7d24c1a99476f816721181e9d18 236 Hamap MF_01121 NAD-dependent protein deacylase [cobB]. 3 236 50.831 T 13-10-2018 IPR027546 Sirtuin, class III GO:0036054|GO:0036055|GO:0070403 Reactome: R-HSA-2151201 Astex_1628 d88ab7d24c1a99476f816721181e9d18 236 Pfam PF02146 Sir2 family 10 186 1.2E-38 T 13-10-2018 IPR003000 Sirtuin family GO:0070403 Astex_2036 e252eb79471e83fe2087392f20dad793 1144 Gene3D G3DSA:3.40.920.10 712 912 6.4E-18 T 13-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 Astex_2036 e252eb79471e83fe2087392f20dad793 1144 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 452 538 9.0E-6 T 13-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 Astex_2036 e252eb79471e83fe2087392f20dad793 1144 Gene3D G3DSA:3.40.50.970 10 222 2.1E-25 T 13-10-2018 Astex_2036 e252eb79471e83fe2087392f20dad793 1144 SUPERFAMILY SSF53323 715 949 9.55E-18 T 13-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 Astex_2036 e252eb79471e83fe2087392f20dad793 1144 SUPERFAMILY SSF52922 269 349 9.94E-6 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 Astex_2036 e252eb79471e83fe2087392f20dad793 1144 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 723 908 8.2E-21 T 13-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 Astex_2036 e252eb79471e83fe2087392f20dad793 1144 SUPERFAMILY SSF52518 432 615 6.81E-13 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold Astex_2036 e252eb79471e83fe2087392f20dad793 1144 SUPERFAMILY SSF52518 21 218 5.65E-15 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold Astex_0260 865ef3c0e71011003b2d4ba07908de81 223 Hamap MF_01416 ATP synthase subunit delta [atpD]. 45 222 17.969 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_0260 865ef3c0e71011003b2d4ba07908de81 223 PRINTS PR00125 ATP synthase delta subunit signature 49 68 9.7E-21 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_0260 865ef3c0e71011003b2d4ba07908de81 223 PRINTS PR00125 ATP synthase delta subunit signature 180 195 9.7E-21 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_0260 865ef3c0e71011003b2d4ba07908de81 223 PRINTS PR00125 ATP synthase delta subunit signature 119 130 9.7E-21 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_0260 865ef3c0e71011003b2d4ba07908de81 223 PRINTS PR00125 ATP synthase delta subunit signature 130 144 9.7E-21 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_0260 865ef3c0e71011003b2d4ba07908de81 223 PRINTS PR00125 ATP synthase delta subunit signature 195 213 9.7E-21 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_0260 865ef3c0e71011003b2d4ba07908de81 223 SUPERFAMILY SSF47928 47 151 8.89E-19 T 13-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_0260 865ef3c0e71011003b2d4ba07908de81 223 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 49 217 2.0E-31 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_0260 865ef3c0e71011003b2d4ba07908de81 223 Pfam PF00213 ATP synthase delta (OSCP) subunit 50 220 4.7E-44 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_0260 865ef3c0e71011003b2d4ba07908de81 223 Gene3D G3DSA:1.10.520.20 49 143 1.7E-15 T 13-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_0129 a73c392f0084cc829f677aeed813365d 169 SUPERFAMILY SSF141523 37 167 4.84E-6 T 13-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like Astex_0129 a73c392f0084cc829f677aeed813365d 169 Pfam PF03734 L,D-transpeptidase catalytic domain 8 167 3.7E-8 T 13-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 Astex_3821 d25b0d1832370f0a7266b5e70915001a 376 Gene3D G3DSA:3.40.50.360 142 376 3.1E-79 T 13-10-2018 IPR029039 Flavoprotein-like superfamily Astex_3821 d25b0d1832370f0a7266b5e70915001a 376 Pfam PF03960 ArsC family 6 113 2.9E-10 T 13-10-2018 IPR006660 Arsenate reductase-like Astex_3821 d25b0d1832370f0a7266b5e70915001a 376 SUPERFAMILY SSF52218 143 364 2.72E-64 T 13-10-2018 IPR029039 Flavoprotein-like superfamily Astex_3821 d25b0d1832370f0a7266b5e70915001a 376 Pfam PF03358 NADPH-dependent FMN reductase 170 313 4.3E-27 T 13-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 Astex_3821 d25b0d1832370f0a7266b5e70915001a 376 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 5 115 1.0E-33 T 13-10-2018 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 Astex_3821 d25b0d1832370f0a7266b5e70915001a 376 TIGRFAM TIGR02690 resist_ArsH: arsenical resistance protein ArsH 144 362 4.2E-123 T 13-10-2018 IPR014063 Arsenate resistance ArsH Astex_3821 d25b0d1832370f0a7266b5e70915001a 376 SUPERFAMILY SSF52833 4 134 1.91E-30 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Astex_3821 d25b0d1832370f0a7266b5e70915001a 376 Gene3D G3DSA:3.40.30.10 1 140 7.5E-48 T 13-10-2018 Astex_0572 3b60629f3e66ba0a5e2b7f24def7a439 977 Gene3D G3DSA:1.25.40.10 98 210 2.2E-11 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_0572 3b60629f3e66ba0a5e2b7f24def7a439 977 Pfam PF07721 Tetratricopeptide repeat 352 371 0.29 T 13-10-2018 IPR011717 Tetratricopeptide TPR-4 GO:0042802 Astex_0572 3b60629f3e66ba0a5e2b7f24def7a439 977 Gene3D G3DSA:1.25.40.10 211 591 5.6E-27 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_0572 3b60629f3e66ba0a5e2b7f24def7a439 977 Pfam PF12770 CHAT domain 689 975 1.6E-41 T 13-10-2018 IPR024983 CHAT domain Astex_0572 3b60629f3e66ba0a5e2b7f24def7a439 977 Pfam PF13374 Tetratricopeptide repeat 308 332 0.011 T 13-10-2018 Astex_0572 3b60629f3e66ba0a5e2b7f24def7a439 977 SUPERFAMILY SSF48452 251 423 3.8E-11 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_0572 3b60629f3e66ba0a5e2b7f24def7a439 977 SUPERFAMILY SSF48452 88 290 1.23E-14 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_0572 3b60629f3e66ba0a5e2b7f24def7a439 977 Pfam PF13424 Tetratricopeptide repeat 136 209 2.8E-11 T 13-10-2018 Astex_0572 3b60629f3e66ba0a5e2b7f24def7a439 977 Pfam PF13424 Tetratricopeptide repeat 222 291 2.3E-8 T 13-10-2018 Astex_0572 3b60629f3e66ba0a5e2b7f24def7a439 977 SMART SM00028 178 211 15.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Astex_0572 3b60629f3e66ba0a5e2b7f24def7a439 977 SMART SM00028 303 336 450.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Astex_0572 3b60629f3e66ba0a5e2b7f24def7a439 977 SMART SM00028 136 169 45.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Astex_0572 3b60629f3e66ba0a5e2b7f24def7a439 977 SMART SM00028 261 294 36.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Astex_0572 3b60629f3e66ba0a5e2b7f24def7a439 977 SMART SM00028 346 379 58.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Astex_1944 f7b681908cb4771a2c7ba313ed380a70 433 Pfam PF13006 Insertion element 4 transposase N-terminal 9 101 3.0E-29 T 13-10-2018 IPR024473 Transposase, IS4, N-terminal Astex_1944 f7b681908cb4771a2c7ba313ed380a70 433 SUPERFAMILY SSF53098 90 369 1.29E-28 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily Astex_1944 f7b681908cb4771a2c7ba313ed380a70 433 Pfam PF01609 Transposase DDE domain 122 346 1.9E-20 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 Astex_0440 132db94799588c979106000b4005582d 179 Gene3D G3DSA:3.40.30.10 23 174 6.7E-35 T 13-10-2018 Astex_0440 132db94799588c979106000b4005582d 179 SUPERFAMILY SSF52833 42 171 2.0E-31 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Astex_0440 132db94799588c979106000b4005582d 179 TIGRFAM TIGR00385 dsbE: periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily 9 165 6.0E-42 T 13-10-2018 IPR004799 Periplasmic protein thiol:disulphide oxidoreductase DsbE GO:0015036|GO:0017004|GO:0030288 Astex_0440 132db94799588c979106000b4005582d 179 Pfam PF08534 Redoxin 37 162 2.1E-16 T 13-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 Astex_0440 132db94799588c979106000b4005582d 179 ProSitePatterns PS00194 Thioredoxin family active site. 69 87 - T 13-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 Astex_1747 473bce77ca2d60e97fc7df38bf8dcd5e 171 Gene3D G3DSA:2.30.30.220 1 125 2.2E-45 T 13-10-2018 IPR036760 SspB-like superfamily Astex_1747 473bce77ca2d60e97fc7df38bf8dcd5e 171 Pfam PF04386 Stringent starvation protein B 16 154 2.2E-43 T 13-10-2018 IPR007481 Stringent starvation protein B Astex_1747 473bce77ca2d60e97fc7df38bf8dcd5e 171 SUPERFAMILY SSF101738 9 123 5.76E-43 T 13-10-2018 IPR036760 SspB-like superfamily Astex_0857 06f58ebf70d618f68f429ac2d2903b13 282 PIRSF PIRSF006250 8 282 9.9E-97 T 13-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 Astex_0857 06f58ebf70d618f68f429ac2d2903b13 282 SUPERFAMILY SSF51690 115 280 3.92E-60 T 13-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 Astex_0857 06f58ebf70d618f68f429ac2d2903b13 282 Gene3D G3DSA:3.20.20.70 118 271 3.4E-103 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_0857 06f58ebf70d618f68f429ac2d2903b13 282 Gene3D G3DSA:3.90.1170.20 17 280 3.4E-103 T 13-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 Astex_0857 06f58ebf70d618f68f429ac2d2903b13 282 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 115 280 4.4E-61 T 13-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 Astex_0857 06f58ebf70d618f68f429ac2d2903b13 282 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 15 280 8.2E-96 T 13-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 Astex_0857 06f58ebf70d618f68f429ac2d2903b13 282 SUPERFAMILY SSF54675 5 114 1.69E-29 T 13-10-2018 Astex_0857 06f58ebf70d618f68f429ac2d2903b13 282 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 26 113 8.2E-25 T 13-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 Astex_1902 b20e17734d2f8902d88c01167a34d6bb 335 Gene3D G3DSA:3.20.20.100 6 321 6.0E-57 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily Astex_1902 b20e17734d2f8902d88c01167a34d6bb 335 Pfam PF00248 Aldo/keto reductase family 19 319 6.2E-39 T 13-10-2018 IPR023210 NADP-dependent oxidoreductase domain Astex_1902 b20e17734d2f8902d88c01167a34d6bb 335 SUPERFAMILY SSF51430 7 320 1.96E-57 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily Astex_1123 5905babf0e10c7a9c69a5046ed1c7f80 360 SMART SM00478 53 202 2.8E-43 T 13-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 Astex_1123 5905babf0e10c7a9c69a5046ed1c7f80 360 Gene3D G3DSA:1.10.340.30 29 146 3.0E-77 T 13-10-2018 Astex_1123 5905babf0e10c7a9c69a5046ed1c7f80 360 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 50 177 1.0E-16 T 13-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 Astex_1123 5905babf0e10c7a9c69a5046ed1c7f80 360 Gene3D G3DSA:3.90.79.10 237 360 2.6E-10 T 13-10-2018 Astex_1123 5905babf0e10c7a9c69a5046ed1c7f80 360 Gene3D G3DSA:1.10.1670.10 15 222 3.0E-77 T 13-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 Astex_1123 5905babf0e10c7a9c69a5046ed1c7f80 360 SUPERFAMILY SSF55811 232 351 1.36E-14 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 Astex_1123 5905babf0e10c7a9c69a5046ed1c7f80 360 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 16 279 1.9E-87 T 13-10-2018 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 Astex_1123 5905babf0e10c7a9c69a5046ed1c7f80 360 SUPERFAMILY SSF48150 15 234 5.97E-66 T 13-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 Astex_1123 5905babf0e10c7a9c69a5046ed1c7f80 360 Pfam PF14815 NUDIX domain 247 359 4.4E-14 T 13-10-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 Astex_1123 5905babf0e10c7a9c69a5046ed1c7f80 360 Pfam PF00633 Helix-hairpin-helix motif 113 142 4.3E-6 T 13-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 Astex_3255 72fa78933d830b9d4fcb38025096c8e4 132 Pfam PF00293 NUDIX domain 5 126 1.7E-23 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 Astex_3255 72fa78933d830b9d4fcb38025096c8e4 132 Gene3D G3DSA:3.90.79.10 1 132 2.5E-44 T 13-10-2018 Astex_3255 72fa78933d830b9d4fcb38025096c8e4 132 TIGRFAM TIGR00586 mutt: mutator mutT protein 1 128 1.6E-30 T 13-10-2018 IPR003561 Mutator MutT GO:0006281|GO:0008413 MetaCyc: PWY-6502 Astex_3255 72fa78933d830b9d4fcb38025096c8e4 132 PRINTS PR00502 NUDIX hydrolase family signature 47 62 1.5E-9 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 Astex_3255 72fa78933d830b9d4fcb38025096c8e4 132 PRINTS PR00502 NUDIX hydrolase family signature 33 47 1.5E-9 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 Astex_3255 72fa78933d830b9d4fcb38025096c8e4 132 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 13-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 Astex_3255 72fa78933d830b9d4fcb38025096c8e4 132 SUPERFAMILY SSF55811 1 128 5.01E-42 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 Astex_2476 47d5d7660bddc104ee883a436186d372 776 SMART SM00342 222 307 2.6E-25 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Astex_2476 47d5d7660bddc104ee883a436186d372 776 Gene3D G3DSA:3.10.28.20 704 776 3.7E-12 T 13-10-2018 Astex_2476 47d5d7660bddc104ee883a436186d372 776 Gene3D G3DSA:1.10.10.60 202 316 3.8E-28 T 13-10-2018 Astex_2476 47d5d7660bddc104ee883a436186d372 776 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 276 291 2.8E-6 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 Astex_2476 47d5d7660bddc104ee883a436186d372 776 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 291 307 2.8E-6 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 Astex_2476 47d5d7660bddc104ee883a436186d372 776 Pfam PF12833 Helix-turn-helix domain 228 308 2.0E-21 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Astex_2476 47d5d7660bddc104ee883a436186d372 776 Pfam PF03069 Acetamidase/Formamidase family 455 597 1.5E-5 T 13-10-2018 IPR004304 Acetamidase/Formamidase GO:0016811 Astex_2476 47d5d7660bddc104ee883a436186d372 776 Pfam PF03069 Acetamidase/Formamidase family 602 760 6.5E-18 T 13-10-2018 IPR004304 Acetamidase/Formamidase GO:0016811 Astex_2476 47d5d7660bddc104ee883a436186d372 776 Gene3D G3DSA:2.60.120.580 361 502 2.0E-10 T 13-10-2018 Astex_2476 47d5d7660bddc104ee883a436186d372 776 Gene3D G3DSA:2.60.120.580 573 668 2.2E-25 T 13-10-2018 Astex_2476 47d5d7660bddc104ee883a436186d372 776 SUPERFAMILY SSF141130 369 774 3.27E-76 T 13-10-2018 Astex_2476 47d5d7660bddc104ee883a436186d372 776 Pfam PF14525 AraC-binding-like domain 66 169 2.1E-8 T 13-10-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like Astex_2476 47d5d7660bddc104ee883a436186d372 776 SUPERFAMILY SSF46689 257 309 2.33E-10 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Astex_3263 6c17256dfab217efbfa276dd92fa0dcf 242 SMART SM00563 71 185 1.9E-20 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 Astex_3263 6c17256dfab217efbfa276dd92fa0dcf 242 SUPERFAMILY SSF69593 7 233 5.36E-32 T 13-10-2018 Astex_3263 6c17256dfab217efbfa276dd92fa0dcf 242 Pfam PF01553 Acyltransferase 57 173 1.5E-14 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 Astex_1987 0e6f82324e7058711bc4bf0206fd9b09 951 Gene3D G3DSA:2.170.130.10 48 171 5.6E-16 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_1987 0e6f82324e7058711bc4bf0206fd9b09 951 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 48 951 1.0E-178 T 13-10-2018 IPR010104 Bacterial TonB-dependent receptor Astex_1987 0e6f82324e7058711bc4bf0206fd9b09 951 Pfam PF00593 TonB dependent receptor 443 950 1.6E-26 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_1987 0e6f82324e7058711bc4bf0206fd9b09 951 SUPERFAMILY SSF56935 35 951 5.13E-77 T 13-10-2018 Astex_1987 0e6f82324e7058711bc4bf0206fd9b09 951 Pfam PF07715 TonB-dependent Receptor Plug Domain 65 168 2.0E-15 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_3315 68af8e1d929d6e31db7cd405737afb47 882 PRINTS PR00133 Glycosyl hydrolase family 3 signature 263 281 1.6E-11 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_3315 68af8e1d929d6e31db7cd405737afb47 882 PRINTS PR00133 Glycosyl hydrolase family 3 signature 96 115 1.6E-11 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_3315 68af8e1d929d6e31db7cd405737afb47 882 PRINTS PR00133 Glycosyl hydrolase family 3 signature 192 208 1.6E-11 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_3315 68af8e1d929d6e31db7cd405737afb47 882 SMART SM01217 787 855 2.1E-23 T 13-10-2018 IPR026891 Fibronectin type III-like domain Astex_3315 68af8e1d929d6e31db7cd405737afb47 882 SUPERFAMILY SSF56988 500 631 1.57E-25 T 13-10-2018 Astex_3315 68af8e1d929d6e31db7cd405737afb47 882 Pfam PF07691 PA14 domain 510 593 6.7E-18 T 13-10-2018 IPR011658 PA14 domain Astex_3315 68af8e1d929d6e31db7cd405737afb47 882 SUPERFAMILY SSF51445 35 381 6.95E-95 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_3315 68af8e1d929d6e31db7cd405737afb47 882 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 83 343 1.0E-43 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_3315 68af8e1d929d6e31db7cd405737afb47 882 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 384 749 9.2E-62 T 13-10-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 Astex_3315 68af8e1d929d6e31db7cd405737afb47 882 Gene3D G3DSA:2.60.40.10 753 860 8.6E-27 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_3315 68af8e1d929d6e31db7cd405737afb47 882 SMART SM00758 471 601 3.5E-19 T 13-10-2018 IPR011658 PA14 domain Astex_3315 68af8e1d929d6e31db7cd405737afb47 882 Gene3D G3DSA:3.40.50.1700 540 752 1.1E-54 T 13-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 Astex_3315 68af8e1d929d6e31db7cd405737afb47 882 Pfam PF14310 Fibronectin type III-like domain 787 853 1.8E-17 T 13-10-2018 IPR026891 Fibronectin type III-like domain Astex_3315 68af8e1d929d6e31db7cd405737afb47 882 Gene3D G3DSA:3.20.20.300 42 362 7.4E-102 T 13-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 Astex_3315 68af8e1d929d6e31db7cd405737afb47 882 SUPERFAMILY SSF52279 384 753 1.83E-53 T 13-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 Astex_3315 68af8e1d929d6e31db7cd405737afb47 882 Gene3D G3DSA:3.40.50.1700 367 496 1.7E-18 T 13-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 Astex_1253 8fd31c3c3e27b326904fb5ef56589310 143 SUPERFAMILY SSF109635 11 101 1.1E-33 T 13-10-2018 IPR037187 DksA, N-terminal domain superfamily Astex_1253 8fd31c3c3e27b326904fb5ef56589310 143 TIGRFAM TIGR02420 dksA: RNA polymerase-binding protein DksA 23 132 2.7E-45 T 13-10-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 Astex_1253 8fd31c3c3e27b326904fb5ef56589310 143 Hamap MF_00926 RNA polymerase-binding transcription factor DksA [dksA]. 19 141 29.284 T 13-10-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 Astex_1253 8fd31c3c3e27b326904fb5ef56589310 143 Gene3D G3DSA:1.20.120.910 8 143 1.3E-38 T 13-10-2018 Astex_1253 8fd31c3c3e27b326904fb5ef56589310 143 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 105 129 - T 13-10-2018 IPR020458 Zinc finger, DksA/TraR C4-type conserved site Astex_1253 8fd31c3c3e27b326904fb5ef56589310 143 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 100 135 3.8E-13 T 13-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 Astex_1253 8fd31c3c3e27b326904fb5ef56589310 143 SUPERFAMILY SSF57716 102 140 8.13E-9 T 13-10-2018 Astex_3027 5157a64038edc9fbeb72a5171a910720 490 SUPERFAMILY SSF52949 8 173 3.47E-19 T 13-10-2018 Astex_3027 5157a64038edc9fbeb72a5171a910720 490 Gene3D G3DSA:3.40.630.10 172 487 1.4E-128 T 13-10-2018 Astex_3027 5157a64038edc9fbeb72a5171a910720 490 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 175 480 4.0E-123 T 13-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 Astex_3027 5157a64038edc9fbeb72a5171a910720 490 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 335 342 - T 13-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 Astex_3027 5157a64038edc9fbeb72a5171a910720 490 SUPERFAMILY SSF53187 168 487 1.22E-117 T 13-10-2018 Astex_3027 5157a64038edc9fbeb72a5171a910720 490 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 17 134 1.4E-13 T 13-10-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 Astex_3027 5157a64038edc9fbeb72a5171a910720 490 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 1 489 34.532 T 13-10-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 Astex_3027 5157a64038edc9fbeb72a5171a910720 490 Gene3D G3DSA:3.40.220.10 1 171 2.0E-21 T 13-10-2018 Astex_3027 5157a64038edc9fbeb72a5171a910720 490 PRINTS PR00481 Cytosol aminopeptidase signature 272 293 5.5E-52 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 Astex_3027 5157a64038edc9fbeb72a5171a910720 490 PRINTS PR00481 Cytosol aminopeptidase signature 360 375 5.5E-52 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 Astex_3027 5157a64038edc9fbeb72a5171a910720 490 PRINTS PR00481 Cytosol aminopeptidase signature 250 267 5.5E-52 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 Astex_3027 5157a64038edc9fbeb72a5171a910720 490 PRINTS PR00481 Cytosol aminopeptidase signature 331 351 5.5E-52 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 Astex_3027 5157a64038edc9fbeb72a5171a910720 490 PRINTS PR00481 Cytosol aminopeptidase signature 309 330 5.5E-52 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 Astex_2877 f81dc8e2c9ac3c027ac719087748729c 212 Hamap MF_00165 Thymidylate kinase [tmk]. 4 206 28.562 T 13-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 Astex_2877 f81dc8e2c9ac3c027ac719087748729c 212 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 2 198 5.3E-47 T 13-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 Astex_2877 f81dc8e2c9ac3c027ac719087748729c 212 Gene3D G3DSA:3.40.50.300 1 206 3.9E-62 T 13-10-2018 Astex_2877 f81dc8e2c9ac3c027ac719087748729c 212 ProSitePatterns PS01331 Thymidylate kinase signature. 93 105 - T 13-10-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 Astex_2877 f81dc8e2c9ac3c027ac719087748729c 212 SUPERFAMILY SSF52540 1 208 3.91E-54 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2877 f81dc8e2c9ac3c027ac719087748729c 212 Pfam PF02223 Thymidylate kinase 8 197 1.3E-45 T 13-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 Astex_1639 62208f684b0bbbf14d61e99876060674 338 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 7 316 2.5E-118 T 13-10-2018 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 Astex_1639 62208f684b0bbbf14d61e99876060674 338 Pfam PF03741 Integral membrane protein TerC family 85 286 4.9E-55 T 13-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 Astex_3656 be8c034b028cac7c250c609c6d76a399 73 SUPERFAMILY SSF89447 4 53 1.15E-6 T 13-10-2018 IPR037914 SpoVT-AbrB domain superfamily Astex_3656 be8c034b028cac7c250c609c6d76a399 73 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 9 54 4.3E-10 T 13-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 Astex_3656 be8c034b028cac7c250c609c6d76a399 73 Gene3D G3DSA:2.10.260.10 1 73 1.6E-23 T 13-10-2018 Astex_0913 7b11a7520ca8e14f9749f681f42da622 197 Gene3D G3DSA:3.40.30.10 3 191 3.8E-51 T 13-10-2018 Astex_0913 7b11a7520ca8e14f9749f681f42da622 197 Gene3D G3DSA:1.20.1050.10 80 188 3.8E-51 T 13-10-2018 Astex_0913 7b11a7520ca8e14f9749f681f42da622 197 Pfam PF13417 Glutathione S-transferase, N-terminal domain 7 76 4.3E-14 T 13-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 Astex_0913 7b11a7520ca8e14f9749f681f42da622 197 SUPERFAMILY SSF47616 70 196 1.23E-11 T 13-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily Astex_0913 7b11a7520ca8e14f9749f681f42da622 197 SUPERFAMILY SSF52833 1 83 3.87E-15 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Astex_2301 717686f8da2ee31f4e6702a33d6523a7 326 ProSitePatterns PS00893 Nudix box signature. 212 233 - T 13-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 Astex_2301 717686f8da2ee31f4e6702a33d6523a7 326 SUPERFAMILY SSF55811 170 317 4.06E-31 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 Astex_2301 717686f8da2ee31f4e6702a33d6523a7 326 PRINTS PR00502 NUDIX hydrolase family signature 221 236 6.7E-7 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 Astex_2301 717686f8da2ee31f4e6702a33d6523a7 326 PRINTS PR00502 NUDIX hydrolase family signature 207 221 6.7E-7 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 Astex_2301 717686f8da2ee31f4e6702a33d6523a7 326 Pfam PF00293 NUDIX domain 183 302 7.1E-18 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 Astex_2301 717686f8da2ee31f4e6702a33d6523a7 326 Gene3D G3DSA:3.90.79.10 174 318 1.5E-40 T 13-10-2018 Astex_3597 ffc399a8f7509c906448c7afca7c240d 437 SUPERFAMILY SSF81853 58 433 3.4E-76 T 13-10-2018 Astex_3597 ffc399a8f7509c906448c7afca7c240d 437 Gene3D G3DSA:1.50.10.20 29 434 6.7E-130 T 13-10-2018 Astex_3597 ffc399a8f7509c906448c7afca7c240d 437 Pfam PF09492 Pectic acid lyase 120 424 8.4E-81 T 13-10-2018 IPR012669 Pectic acid lyase Astex_3597 ffc399a8f7509c906448c7afca7c240d 437 TIGRFAM TIGR02474 pec_lyase: pectate lyase 120 424 1.4E-91 T 13-10-2018 IPR012669 Pectic acid lyase Astex_2089 7c5a35e7556fef1262e777e3136dbf01 328 Gene3D G3DSA:3.90.550.10 1 222 1.6E-44 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_2089 7c5a35e7556fef1262e777e3136dbf01 328 SUPERFAMILY SSF53448 2 257 2.67E-53 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_2089 7c5a35e7556fef1262e777e3136dbf01 328 Pfam PF00535 Glycosyl transferase family 2 6 172 2.3E-24 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 Astex_3421 030e134e56cdda8177974ee45b781c3a 319 SUPERFAMILY SSF53474 65 317 2.91E-46 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_3421 030e134e56cdda8177974ee45b781c3a 319 Pfam PF07859 alpha/beta hydrolase fold 92 298 5.9E-24 T 13-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 Astex_3421 030e134e56cdda8177974ee45b781c3a 319 Gene3D G3DSA:3.40.50.1820 34 317 7.5E-53 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_0850 9b6269dc4e65bb52e60cee8509a21450 258 TIGRFAM TIGR03170 flgA_cterm: flagella basal body P-ring formation protein FlgA 111 242 1.1E-30 T 13-10-2018 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal Astex_0850 9b6269dc4e65bb52e60cee8509a21450 258 SMART SM00858 119 181 9.9E-10 T 13-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 Astex_0850 9b6269dc4e65bb52e60cee8509a21450 258 Gene3D G3DSA:2.30.30.760 184 252 2.9E-7 T 13-10-2018 Astex_0850 9b6269dc4e65bb52e60cee8509a21450 258 Pfam PF13144 Chaperone for flagella basal body P-ring formation 112 242 3.7E-30 T 13-10-2018 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal Astex_2518 83d88a715f5b2de93d948588e9f871cc 203 Pfam PF02525 Flavodoxin-like fold 3 199 1.1E-42 T 13-10-2018 IPR003680 Flavodoxin-like fold Astex_2518 83d88a715f5b2de93d948588e9f871cc 203 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 201 28.699 T 13-10-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 Astex_2518 83d88a715f5b2de93d948588e9f871cc 203 Gene3D G3DSA:3.40.50.360 1 203 1.3E-54 T 13-10-2018 IPR029039 Flavoprotein-like superfamily Astex_2518 83d88a715f5b2de93d948588e9f871cc 203 SUPERFAMILY SSF52218 1 201 1.55E-48 T 13-10-2018 IPR029039 Flavoprotein-like superfamily Astex_1058 9942afc752ca5b7aa34fbead6104d9d4 233 Gene3D G3DSA:3.90.1680.20 11 114 4.5E-30 T 13-10-2018 Astex_1058 9942afc752ca5b7aa34fbead6104d9d4 233 Gene3D G3DSA:3.90.1680.20 115 197 1.5E-22 T 13-10-2018 Astex_1058 9942afc752ca5b7aa34fbead6104d9d4 233 Pfam PF02586 SOS response associated peptidase (SRAP) 2 208 3.3E-19 T 13-10-2018 IPR003738 SOS response associated peptidase (SRAP) Astex_1058 9942afc752ca5b7aa34fbead6104d9d4 233 SUPERFAMILY SSF143081 2 216 3.01E-62 T 13-10-2018 IPR036590 SOS response associated peptidase-like Astex_3084 a410eb53d9b57f9695e12fbe553c14ea 262 SMART SM00987 83 243 3.6E-38 T 13-10-2018 Astex_3084 a410eb53d9b57f9695e12fbe553c14ea 262 SMART SM00986 83 243 3.6E-38 T 13-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Astex_3084 a410eb53d9b57f9695e12fbe553c14ea 262 Pfam PF03167 Uracil DNA glycosylase superfamily 88 243 5.3E-25 T 13-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Astex_3084 a410eb53d9b57f9695e12fbe553c14ea 262 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 40 246 1.9E-79 T 13-10-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Astex_3084 a410eb53d9b57f9695e12fbe553c14ea 262 SUPERFAMILY SSF52141 37 254 3.05E-91 T 13-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Astex_3084 a410eb53d9b57f9695e12fbe553c14ea 262 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 38 254 40.332 T 13-10-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Astex_3084 a410eb53d9b57f9695e12fbe553c14ea 262 Gene3D G3DSA:3.40.470.10 31 258 3.5E-98 T 13-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Astex_3084 a410eb53d9b57f9695e12fbe553c14ea 262 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 91 100 - T 13-10-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Astex_0543 7c00dde1ce02f6eb8fa54d3ff3c8e8bc 292 SUPERFAMILY SSF46689 14 91 1.13E-18 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Astex_0543 7c00dde1ce02f6eb8fa54d3ff3c8e8bc 292 Gene3D G3DSA:1.10.10.10 11 93 1.4E-25 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_0543 7c00dde1ce02f6eb8fa54d3ff3c8e8bc 292 Gene3D G3DSA:3.40.50.10490 106 288 1.0E-42 T 13-10-2018 Astex_0543 7c00dde1ce02f6eb8fa54d3ff3c8e8bc 292 Pfam PF01418 Helix-turn-helix domain, rpiR family 15 89 4.6E-19 T 13-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 Astex_0543 7c00dde1ce02f6eb8fa54d3ff3c8e8bc 292 Pfam PF01380 SIS domain 138 266 1.3E-17 T 13-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 Astex_0543 7c00dde1ce02f6eb8fa54d3ff3c8e8bc 292 SUPERFAMILY SSF53697 104 289 1.96E-37 T 13-10-2018 Astex_2708 5278b6651d06bbd9b1f25beb6477ad86 798 Gene3D G3DSA:2.40.170.20 291 797 1.9E-56 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_2708 5278b6651d06bbd9b1f25beb6477ad86 798 Pfam PF07715 TonB-dependent Receptor Plug Domain 55 174 1.4E-20 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_2708 5278b6651d06bbd9b1f25beb6477ad86 798 Gene3D G3DSA:2.170.130.10 33 178 2.4E-33 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_2708 5278b6651d06bbd9b1f25beb6477ad86 798 SUPERFAMILY SSF56935 40 798 3.66E-107 T 13-10-2018 Astex_2708 5278b6651d06bbd9b1f25beb6477ad86 798 Pfam PF00593 TonB dependent receptor 323 794 1.7E-44 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_3322 45ee23256aa77b9606f0647b1173bd29 139 Pfam PF00072 Response regulator receiver domain 6 118 8.8E-19 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_3322 45ee23256aa77b9606f0647b1173bd29 139 SMART SM00448 3 125 2.5E-19 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_3322 45ee23256aa77b9606f0647b1173bd29 139 Gene3D G3DSA:3.40.50.2300 2 139 1.2E-33 T 13-10-2018 Astex_3322 45ee23256aa77b9606f0647b1173bd29 139 SUPERFAMILY SSF52172 3 134 2.7E-30 T 13-10-2018 IPR011006 CheY-like superfamily Astex_0777 003616b3c1ac7df5e4475621b31d8e92 885 Pfam PF08448 PAS fold 63 175 1.1E-6 T 13-10-2018 IPR013656 PAS fold-4 Astex_0777 003616b3c1ac7df5e4475621b31d8e92 885 SUPERFAMILY SSF55785 660 756 2.74E-11 T 13-10-2018 IPR035965 PAS domain superfamily Astex_0777 003616b3c1ac7df5e4475621b31d8e92 885 Pfam PF08447 PAS fold 669 751 2.6E-9 T 13-10-2018 IPR013655 PAS fold-3 GO:0005515 Astex_0777 003616b3c1ac7df5e4475621b31d8e92 885 Pfam PF13426 PAS domain 199 298 0.14 T 13-10-2018 IPR000014 PAS domain Astex_0777 003616b3c1ac7df5e4475621b31d8e92 885 SUPERFAMILY SSF55785 46 167 2.58E-12 T 13-10-2018 IPR035965 PAS domain superfamily Astex_0777 003616b3c1ac7df5e4475621b31d8e92 885 SMART SM00091 642 711 26.0 T 13-10-2018 IPR000014 PAS domain Astex_0777 003616b3c1ac7df5e4475621b31d8e92 885 SMART SM00091 57 129 1.1E-4 T 13-10-2018 IPR000014 PAS domain Astex_0777 003616b3c1ac7df5e4475621b31d8e92 885 SMART SM00091 189 256 1.9 T 13-10-2018 IPR000014 PAS domain Astex_0777 003616b3c1ac7df5e4475621b31d8e92 885 Gene3D G3DSA:3.30.450.20 641 753 2.7E-12 T 13-10-2018 Astex_0777 003616b3c1ac7df5e4475621b31d8e92 885 Gene3D G3DSA:3.30.450.20 193 306 7.0E-6 T 13-10-2018 Astex_0777 003616b3c1ac7df5e4475621b31d8e92 885 Gene3D G3DSA:1.10.287.130 810 880 2.2E-6 T 13-10-2018 Astex_0777 003616b3c1ac7df5e4475621b31d8e92 885 SUPERFAMILY SSF55785 195 297 7.5E-8 T 13-10-2018 IPR035965 PAS domain superfamily Astex_0777 003616b3c1ac7df5e4475621b31d8e92 885 Gene3D G3DSA:3.30.450.20 45 179 3.7E-12 T 13-10-2018 Astex_0916 13542bf6518924dcb5c6d7ed66c7cd33 264 SUPERFAMILY SSF50800 2 260 4.92E-30 T 13-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily Astex_0916 13542bf6518924dcb5c6d7ed66c7cd33 264 Pfam PF03473 MOSC domain 141 259 5.0E-17 T 13-10-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 Astex_0916 13542bf6518924dcb5c6d7ed66c7cd33 264 Pfam PF03476 MOSC N-terminal beta barrel domain 6 90 6.1E-11 T 13-10-2018 IPR005303 MOSC, N-terminal beta barrel KEGG: 00790+2.8.1.9|MetaCyc: PWY-5963 Astex_0916 13542bf6518924dcb5c6d7ed66c7cd33 264 Gene3D G3DSA:2.40.33.20 135 263 1.4E-14 T 13-10-2018 Astex_0938 008b2329a8dfce50d2e9f611ae089288 123 SUPERFAMILY SSF50249 2 123 6.85E-50 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Astex_0938 008b2329a8dfce50d2e9f611ae089288 123 Pfam PF00164 Ribosomal protein S12/S23 14 123 2.2E-38 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_0938 008b2329a8dfce50d2e9f611ae089288 123 PIRSF PIRSF002133 1 123 6.8E-52 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_0938 008b2329a8dfce50d2e9f611ae089288 123 PRINTS PR01034 Ribosomal protein S12 signature 58 77 1.2E-57 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_0938 008b2329a8dfce50d2e9f611ae089288 123 PRINTS PR01034 Ribosomal protein S12 signature 27 42 1.2E-57 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_0938 008b2329a8dfce50d2e9f611ae089288 123 PRINTS PR01034 Ribosomal protein S12 signature 42 57 1.2E-57 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_0938 008b2329a8dfce50d2e9f611ae089288 123 PRINTS PR01034 Ribosomal protein S12 signature 110 122 1.2E-57 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_0938 008b2329a8dfce50d2e9f611ae089288 123 PRINTS PR01034 Ribosomal protein S12 signature 77 94 1.2E-57 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_0938 008b2329a8dfce50d2e9f611ae089288 123 PRINTS PR01034 Ribosomal protein S12 signature 94 110 1.2E-57 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_0938 008b2329a8dfce50d2e9f611ae089288 123 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 123 1.0E-64 T 13-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0938 008b2329a8dfce50d2e9f611ae089288 123 Gene3D G3DSA:2.40.50.140 1 123 1.1E-61 T 13-10-2018 Astex_0938 008b2329a8dfce50d2e9f611ae089288 123 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_0938 008b2329a8dfce50d2e9f611ae089288 123 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 38.705 T 13-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_3275 bcbe29f658da2e507ca952b5889c6c8c 315 Pfam PF06271 RDD family 44 202 8.1E-18 T 13-10-2018 IPR010432 RDD Astex_3674 a62f0fea8d820effa07e9cb557e802fb 298 Gene3D G3DSA:3.40.190.10 163 269 3.9E-55 T 13-10-2018 Astex_3674 a62f0fea8d820effa07e9cb557e802fb 298 Pfam PF03466 LysR substrate binding domain 88 293 2.1E-36 T 13-10-2018 IPR005119 LysR, substrate-binding Astex_3674 a62f0fea8d820effa07e9cb557e802fb 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 2.1E-22 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_3674 a62f0fea8d820effa07e9cb557e802fb 298 Gene3D G3DSA:1.10.10.10 1 86 5.8E-30 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_3674 a62f0fea8d820effa07e9cb557e802fb 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.3E-9 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_3674 a62f0fea8d820effa07e9cb557e802fb 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.3E-9 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_3674 a62f0fea8d820effa07e9cb557e802fb 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.3E-9 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_3674 a62f0fea8d820effa07e9cb557e802fb 298 SUPERFAMILY SSF53850 88 296 8.55E-36 T 13-10-2018 Astex_3674 a62f0fea8d820effa07e9cb557e802fb 298 Gene3D G3DSA:3.40.190.10 89 285 3.9E-55 T 13-10-2018 Astex_3674 a62f0fea8d820effa07e9cb557e802fb 298 SUPERFAMILY SSF46785 3 86 7.69E-24 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_3099 5a13b603c357da324a8277c2df8c3da5 277 Gene3D G3DSA:2.40.100.10 17 244 1.9E-47 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily Astex_3099 5a13b603c357da324a8277c2df8c3da5 277 SUPERFAMILY SSF50891 40 248 3.21E-41 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily Astex_3099 5a13b603c357da324a8277c2df8c3da5 277 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 40 227 4.8E-37 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 Astex_3099 5a13b603c357da324a8277c2df8c3da5 277 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 74 91 - T 13-10-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 Astex_1666 53a8f629b3f52f1424cf470a54735f56 610 Pfam PF00557 Metallopeptidase family M24 329 540 5.3E-44 T 13-10-2018 IPR000994 Peptidase M24 Astex_1666 53a8f629b3f52f1424cf470a54735f56 610 Pfam PF16188 C-terminal region of peptidase_M24 551 610 6.1E-20 T 13-10-2018 IPR032416 Peptidase M24, C-terminal domain Astex_1666 53a8f629b3f52f1424cf470a54735f56 610 Gene3D G3DSA:3.40.350.10 14 162 5.3E-37 T 13-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal Astex_1666 53a8f629b3f52f1424cf470a54735f56 610 SUPERFAMILY SSF53092 25 143 1.34E-9 T 13-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal Astex_1666 53a8f629b3f52f1424cf470a54735f56 610 SUPERFAMILY SSF55920 320 576 3.79E-57 T 13-10-2018 IPR036005 Creatinase/aminopeptidase-like Astex_1666 53a8f629b3f52f1424cf470a54735f56 610 Pfam PF16189 Creatinase/Prolidase N-terminal domain 166 323 2.1E-31 T 13-10-2018 Astex_1666 53a8f629b3f52f1424cf470a54735f56 610 Gene3D G3DSA:3.90.230.10 317 610 2.2E-93 T 13-10-2018 Astex_1666 53a8f629b3f52f1424cf470a54735f56 610 Pfam PF01321 Creatinase/Prolidase N-terminal domain 26 145 2.1E-15 T 13-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 Astex_1666 53a8f629b3f52f1424cf470a54735f56 610 Gene3D G3DSA:3.40.350.10 164 306 1.1E-20 T 13-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal Astex_3046 c82335de4a603157261e94e858ffdec2 752 SUPERFAMILY SSF53474 483 723 3.37E-43 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_3046 c82335de4a603157261e94e858ffdec2 752 Gene3D G3DSA:3.40.50.1820 67 739 2.9E-244 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_3046 c82335de4a603157261e94e858ffdec2 752 Gene3D G3DSA:2.130.10.120 127 471 2.9E-244 T 13-10-2018 Astex_3046 c82335de4a603157261e94e858ffdec2 752 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 55 469 2.0E-72 T 13-10-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 Astex_3046 c82335de4a603157261e94e858ffdec2 752 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 574 604 - T 13-10-2018 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 Astex_3046 c82335de4a603157261e94e858ffdec2 752 Pfam PF00326 Prolyl oligopeptidase family 528 745 1.0E-63 T 13-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 Astex_3046 c82335de4a603157261e94e858ffdec2 752 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 567 586 1.3E-52 T 13-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 Astex_3046 c82335de4a603157261e94e858ffdec2 752 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 656 671 1.3E-52 T 13-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 Astex_3046 c82335de4a603157261e94e858ffdec2 752 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 539 563 1.3E-52 T 13-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 Astex_3046 c82335de4a603157261e94e858ffdec2 752 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 597 617 1.3E-52 T 13-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 Astex_3046 c82335de4a603157261e94e858ffdec2 752 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 674 696 1.3E-52 T 13-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 Astex_3046 c82335de4a603157261e94e858ffdec2 752 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 513 531 1.3E-52 T 13-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 Astex_3046 c82335de4a603157261e94e858ffdec2 752 SUPERFAMILY SSF50993 45 477 2.01E-76 T 13-10-2018 Astex_2678 501b69296585f9dea07118d9ae829c6d 227 SUPERFAMILY SSF143081 29 197 4.45E-20 T 13-10-2018 IPR036590 SOS response associated peptidase-like Astex_2678 501b69296585f9dea07118d9ae829c6d 227 Pfam PF02586 SOS response associated peptidase (SRAP) 53 195 7.0E-13 T 13-10-2018 IPR003738 SOS response associated peptidase (SRAP) Astex_2678 501b69296585f9dea07118d9ae829c6d 227 Gene3D G3DSA:3.90.1680.10 28 211 1.7E-15 T 13-10-2018 IPR036590 SOS response associated peptidase-like Astex_1617 c284e64617bdda85b3de861426707d9d 372 Gene3D G3DSA:3.40.50.2000 19 367 2.1E-66 T 13-10-2018 Astex_1617 c284e64617bdda85b3de861426707d9d 372 Gene3D G3DSA:3.40.50.2000 161 354 2.1E-66 T 13-10-2018 Astex_1617 c284e64617bdda85b3de861426707d9d 372 SUPERFAMILY SSF53756 5 371 5.23E-83 T 13-10-2018 Astex_1617 c284e64617bdda85b3de861426707d9d 372 Pfam PF00534 Glycosyl transferases group 1 188 348 1.0E-28 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 Astex_1617 c284e64617bdda85b3de861426707d9d 372 Pfam PF13439 Glycosyltransferase Family 4 10 164 8.6E-31 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 Astex_1050 9ce760bc176b555f9f76828c339faa24 773 Gene3D G3DSA:2.170.130.10 61 177 8.3E-15 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_1050 9ce760bc176b555f9f76828c339faa24 773 Pfam PF00593 TonB dependent receptor 315 772 1.1E-35 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_1050 9ce760bc176b555f9f76828c339faa24 773 SUPERFAMILY SSF56935 31 772 5.6E-77 T 13-10-2018 Astex_1050 9ce760bc176b555f9f76828c339faa24 773 Pfam PF07715 TonB-dependent Receptor Plug Domain 63 167 2.4E-13 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_2584 342a9aa711574f1e97f1f108979e2d3c 791 Pfam PF07944 Beta-L-arabinofuranosidase, GH127 45 561 7.2E-149 T 13-10-2018 IPR012878 Beta-L-arabinofuranosidase, GH127 Astex_2584 342a9aa711574f1e97f1f108979e2d3c 791 SUPERFAMILY SSF48208 90 407 8.16E-11 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 Astex_2801 93c76c2ec42b432cd09d3ddae745d557 1068 Gene3D G3DSA:2.40.128.130 773 1068 1.7E-31 T 13-10-2018 IPR036709 Autotransporter beta-domain superfamily Astex_2801 93c76c2ec42b432cd09d3ddae745d557 1068 SUPERFAMILY SSF103515 791 1068 1.27E-29 T 13-10-2018 IPR036709 Autotransporter beta-domain superfamily Astex_2801 93c76c2ec42b432cd09d3ddae745d557 1068 Pfam PF03797 Autotransporter beta-domain 799 1037 2.8E-25 T 13-10-2018 IPR005546 Autotransporter beta-domain Astex_2801 93c76c2ec42b432cd09d3ddae745d557 1068 SMART SM00869 795 1058 1.2E-16 T 13-10-2018 IPR005546 Autotransporter beta-domain Astex_1883 0329832159efe96df6d60699a0c0a73f 641 SMART SM00460 526 594 3.1E-20 T 13-10-2018 IPR002931 Transglutaminase-like Astex_1883 0329832159efe96df6d60699a0c0a73f 641 Gene3D G3DSA:3.60.20.10 8 270 9.0E-41 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Astex_1883 0329832159efe96df6d60699a0c0a73f 641 SUPERFAMILY SSF54001 359 621 4.07E-38 T 13-10-2018 IPR038765 Papain-like cysteine peptidase superfamily Astex_1883 0329832159efe96df6d60699a0c0a73f 641 Pfam PF01841 Transglutaminase-like superfamily 494 592 2.0E-22 T 13-10-2018 IPR002931 Transglutaminase-like Astex_1883 0329832159efe96df6d60699a0c0a73f 641 Pfam PF13230 Glutamine amidotransferases class-II 9 274 1.0E-41 T 13-10-2018 IPR026869 Putative glutamine amidotransferase type 2 Astex_1883 0329832159efe96df6d60699a0c0a73f 641 Gene3D G3DSA:3.10.620.30 446 633 1.8E-43 T 13-10-2018 Astex_1883 0329832159efe96df6d60699a0c0a73f 641 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 355 432 7.2E-16 T 13-10-2018 IPR013589 Bacterial transglutaminase-like, N-terminal Astex_1883 0329832159efe96df6d60699a0c0a73f 641 SUPERFAMILY SSF56235 37 268 5.6E-14 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Astex_3268 bdc582fd5448834b13f80d9db2845100 169 Pfam PF00156 Phosphoribosyl transferase domain 6 134 4.8E-15 T 13-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 Astex_3268 bdc582fd5448834b13f80d9db2845100 169 Gene3D G3DSA:3.40.50.2020 1 169 1.8E-46 T 13-10-2018 Astex_3268 bdc582fd5448834b13f80d9db2845100 169 SUPERFAMILY SSF53271 3 168 1.7E-40 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like Astex_2876 4f6bdbb19bd1689abaa5b75937147087 336 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 28 223 1.3E-54 T 13-10-2018 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Astex_2876 4f6bdbb19bd1689abaa5b75937147087 336 SUPERFAMILY SSF52540 23 228 3.46E-44 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2876 4f6bdbb19bd1689abaa5b75937147087 336 Gene3D G3DSA:3.40.50.300 19 190 1.5E-48 T 13-10-2018 Astex_2876 4f6bdbb19bd1689abaa5b75937147087 336 Pfam PF13177 DNA polymerase III, delta subunit 29 189 3.1E-38 T 13-10-2018 Astex_2936 5e5032095d31e33e009de735b72df34c 320 SUPERFAMILY SSF55326 2 142 4.36E-24 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Astex_2936 5e5032095d31e33e009de735b72df34c 320 Pfam PF02769 AIR synthase related protein, C-terminal domain 154 298 1.7E-7 T 13-10-2018 IPR010918 PurM-like, C-terminal domain Astex_2936 5e5032095d31e33e009de735b72df34c 320 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 5 320 22.673 T 13-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 Astex_2936 5e5032095d31e33e009de735b72df34c 320 Gene3D G3DSA:3.30.1330.10 3 148 4.3E-28 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Astex_2936 5e5032095d31e33e009de735b72df34c 320 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 7 319 2.3E-81 T 13-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 Astex_2936 5e5032095d31e33e009de735b72df34c 320 Pfam PF00586 AIR synthase related protein, N-terminal domain 30 141 6.6E-14 T 13-10-2018 IPR016188 PurM-like, N-terminal domain Astex_2936 5e5032095d31e33e009de735b72df34c 320 Gene3D G3DSA:3.90.650.10 150 320 2.0E-38 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Astex_2936 5e5032095d31e33e009de735b72df34c 320 PIRSF PIRSF005303 1 320 1.5E-66 T 13-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 Astex_2936 5e5032095d31e33e009de735b72df34c 320 SUPERFAMILY SSF56042 147 306 2.44E-32 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Astex_2810 7ecb6b19a16f932c3220544218e81902 687 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 5 596 2.3E-217 T 13-10-2018 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2810 7ecb6b19a16f932c3220544218e81902 687 Gene3D G3DSA:3.30.70.20 125 205 5.4E-6 T 13-10-2018 Astex_2810 7ecb6b19a16f932c3220544218e81902 687 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 99 111 - T 13-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2810 7ecb6b19a16f932c3220544218e81902 687 SMART SM00929 84 124 5.6E-21 T 13-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2810 7ecb6b19a16f932c3220544218e81902 687 Gene3D G3DSA:3.40.50.740 488 618 1.9E-17 T 13-10-2018 Astex_2810 7ecb6b19a16f932c3220544218e81902 687 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 146 156 - T 13-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2810 7ecb6b19a16f932c3220544218e81902 687 Gene3D G3DSA:3.10.20.740 2 124 1.6E-37 T 13-10-2018 Astex_2810 7ecb6b19a16f932c3220544218e81902 687 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 5 77 3.2E-12 T 13-10-2018 Astex_2810 7ecb6b19a16f932c3220544218e81902 687 Pfam PF09326 NADH-ubiquinone oxidoreductase subunit G, C-terminal 635 672 6.1E-11 T 13-10-2018 IPR015405 NADH-quinone oxidoreductase, chain G, C-terminal GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2810 7ecb6b19a16f932c3220544218e81902 687 Gene3D G3DSA:3.40.50.740 273 445 5.4E-13 T 13-10-2018 Astex_2810 7ecb6b19a16f932c3220544218e81902 687 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 31 48 - T 13-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2810 7ecb6b19a16f932c3220544218e81902 687 SUPERFAMILY SSF53706 214 625 4.82E-93 T 13-10-2018 Astex_2810 7ecb6b19a16f932c3220544218e81902 687 SUPERFAMILY SSF54292 5 75 4.56E-17 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 Astex_2810 7ecb6b19a16f932c3220544218e81902 687 SUPERFAMILY SSF54862 76 210 3.56E-35 T 13-10-2018 Astex_2810 7ecb6b19a16f932c3220544218e81902 687 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 84 123 9.2E-17 T 13-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2810 7ecb6b19a16f932c3220544218e81902 687 Pfam PF00384 Molybdopterin oxidoreductase 272 425 2.5E-34 T 13-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2810 7ecb6b19a16f932c3220544218e81902 687 Pfam PF00384 Molybdopterin oxidoreductase 431 598 3.7E-30 T 13-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_0098 1e553689ceb43beb403f5938fa5c546d 1060 Pfam PF05592 Bacterial alpha-L-rhamnosidase concanavalin-like domain 509 607 4.5E-33 T 13-10-2018 IPR008902 Alpha-L-rhamnosidase, concanavalin-like domain Astex_0098 1e553689ceb43beb403f5938fa5c546d 1060 Gene3D G3DSA:1.50.10.10 149 1056 9.0E-293 T 13-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 Astex_0098 1e553689ceb43beb403f5938fa5c546d 1060 Pfam PF17390 Bacterial alpha-L-rhamnosidase C-terminal domain 955 1028 3.2E-18 T 13-10-2018 IPR035398 Alpha-L-rhamnosidase C-terminal domain Astex_0098 1e553689ceb43beb403f5938fa5c546d 1060 Pfam PF08531 Alpha-L-rhamnosidase N-terminal domain 328 496 2.4E-55 T 13-10-2018 IPR013737 Bacterial alpha-L-rhamnosidase N-terminal Astex_0098 1e553689ceb43beb403f5938fa5c546d 1060 SUPERFAMILY SSF48208 611 1021 5.05E-41 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 Astex_0098 1e553689ceb43beb403f5938fa5c546d 1060 PIRSF PIRSF010631 12 1059 3.4E-296 T 13-10-2018 IPR016007 Alpha-L-rhamnosidase Astex_0098 1e553689ceb43beb403f5938fa5c546d 1060 SUPERFAMILY SSF49785 276 399 1.56E-5 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_0098 1e553689ceb43beb403f5938fa5c546d 1060 Gene3D G3DSA:2.60.120.260 164 312 9.0E-293 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_0098 1e553689ceb43beb403f5938fa5c546d 1060 Pfam PF17389 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain 612 953 1.0E-112 T 13-10-2018 IPR035396 Alpha-L-rhamnosidase, six-hairpin glycosidase domain Astex_0098 1e553689ceb43beb403f5938fa5c546d 1060 Gene3D G3DSA:2.60.40.10 33 143 2.0E-30 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_0720 c040e8631f51aea426ed420454329e31 133 Pfam PF11412 Disulphide bond corrector protein DsbC 22 124 9.4E-20 T 13-10-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain Astex_0720 c040e8631f51aea426ed420454329e31 133 SUPERFAMILY SSF74863 21 125 2.88E-25 T 13-10-2018 IPR036929 Thiol:disulfide interchange protein DsbD, N-terminal domain superfamily Astex_0720 c040e8631f51aea426ed420454329e31 133 Gene3D G3DSA:2.60.40.1250 12 133 4.5E-28 T 13-10-2018 IPR036929 Thiol:disulfide interchange protein DsbD, N-terminal domain superfamily Astex_3274 e3ec56eb4393abfc366ffdf5474596d9 247 Pfam PF06790 Uncharacterised protein family (UPF0259) 76 163 2.7E-8 T 13-10-2018 IPR009627 Uncharacterised protein family UPF0259 Astex_1086 b94e68d70082317454780d6bb2acc3ca 315 PIRSF PIRSF031900 9 313 4.4E-20 T 13-10-2018 IPR014567 Uncharacterised conserved protein UCP031900 Astex_1086 b94e68d70082317454780d6bb2acc3ca 315 Pfam PF13449 Esterase-like activity of phytase 60 181 3.2E-12 T 13-10-2018 IPR027372 Phytase-like domain Astex_1086 b94e68d70082317454780d6bb2acc3ca 315 SUPERFAMILY SSF50956 108 176 1.14E-5 T 13-10-2018 Astex_3025 858f66076718ba6b849970c75ddf8073 112 Gene3D G3DSA:3.30.10.10 48 111 3.4E-12 T 13-10-2018 Astex_0284 a0e7f0a98f34bbcac6e8fdd156e905ab 207 Gene3D G3DSA:1.10.357.10 3 199 1.8E-25 T 13-10-2018 Astex_0284 a0e7f0a98f34bbcac6e8fdd156e905ab 207 SUPERFAMILY SSF46689 8 86 3.59E-17 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Astex_0284 a0e7f0a98f34bbcac6e8fdd156e905ab 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 1.0E-14 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Astex_0284 a0e7f0a98f34bbcac6e8fdd156e905ab 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 3.2E-10 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Astex_0284 a0e7f0a98f34bbcac6e8fdd156e905ab 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 3.2E-10 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Astex_0170 fd34c48d74359814ca8803e9f528e423 561 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 20 539 19.477 T 13-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 Astex_0170 fd34c48d74359814ca8803e9f528e423 561 SUPERFAMILY SSF56317 290 530 2.75E-27 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily Astex_0170 fd34c48d74359814ca8803e9f528e423 561 Gene3D G3DSA:3.60.110.10 272 512 3.5E-9 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily Astex_0170 fd34c48d74359814ca8803e9f528e423 561 Pfam PF00795 Carbon-nitrogen hydrolase 295 503 2.1E-17 T 13-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 Astex_0170 fd34c48d74359814ca8803e9f528e423 561 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 77 500 2.3E-79 T 13-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 Astex_3038 2dce46d8c806cdc36b53566493751985 142 PRINTS PR00502 NUDIX hydrolase family signature 50 65 1.1E-5 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 Astex_3038 2dce46d8c806cdc36b53566493751985 142 PRINTS PR00502 NUDIX hydrolase family signature 36 50 1.1E-5 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 Astex_3038 2dce46d8c806cdc36b53566493751985 142 Pfam PF00293 NUDIX domain 9 131 2.9E-20 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 Astex_3038 2dce46d8c806cdc36b53566493751985 142 Gene3D G3DSA:3.90.79.10 1 137 5.1E-33 T 13-10-2018 Astex_3038 2dce46d8c806cdc36b53566493751985 142 SUPERFAMILY SSF55811 6 134 1.27E-32 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 Astex_3038 2dce46d8c806cdc36b53566493751985 142 ProSitePatterns PS00893 Nudix box signature. 41 62 - T 13-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 Astex_2310 a435a56bfb016185f11205b5e8469140 501 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 177 273 1.1E-24 T 13-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Astex_2310 a435a56bfb016185f11205b5e8469140 501 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 253 268 4.8E-11 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Astex_2310 a435a56bfb016185f11205b5e8469140 501 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 224 237 4.8E-11 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Astex_2310 a435a56bfb016185f11205b5e8469140 501 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 190 209 4.8E-11 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Astex_2310 a435a56bfb016185f11205b5e8469140 501 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 116 130 4.8E-11 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Astex_2310 a435a56bfb016185f11205b5e8469140 501 Gene3D G3DSA:3.30.310.50 394 491 8.0E-14 T 13-10-2018 Astex_2310 a435a56bfb016185f11205b5e8469140 501 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 27 155 2.4E-26 T 13-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Astex_2310 a435a56bfb016185f11205b5e8469140 501 SUPERFAMILY SSF53738 174 274 1.1E-25 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Astex_2310 a435a56bfb016185f11205b5e8469140 501 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 425 481 4.8E-7 T 13-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Astex_2310 a435a56bfb016185f11205b5e8469140 501 SUPERFAMILY SSF53738 22 155 7.85E-29 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Astex_2310 a435a56bfb016185f11205b5e8469140 501 Gene3D G3DSA:3.40.120.10 22 169 7.9E-30 T 13-10-2018 Astex_2310 a435a56bfb016185f11205b5e8469140 501 Gene3D G3DSA:3.40.120.10 187 380 1.5E-53 T 13-10-2018 Astex_2310 a435a56bfb016185f11205b5e8469140 501 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 279 391 1.7E-18 T 13-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Astex_2310 a435a56bfb016185f11205b5e8469140 501 SUPERFAMILY SSF53738 279 388 2.0E-20 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Astex_2310 a435a56bfb016185f11205b5e8469140 501 Gene3D G3DSA:3.40.120.10 274 384 1.5E-53 T 13-10-2018 Astex_2310 a435a56bfb016185f11205b5e8469140 501 SUPERFAMILY SSF55957 393 480 1.1E-12 T 13-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 Astex_0247 dab98e59e451a99932ca273008257349 313 SUPERFAMILY SSF52540 44 277 5.31E-8 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0247 dab98e59e451a99932ca273008257349 313 Gene3D G3DSA:3.40.50.300 10 287 4.7E-10 T 13-10-2018 Astex_1256 0536f971041e6fd24ea874f360db3514 203 Gene3D G3DSA:3.40.50.450 8 201 1.1E-64 T 13-10-2018 Astex_1256 0536f971041e6fd24ea874f360db3514 203 Pfam PF03641 Possible lysine decarboxylase 58 186 5.4E-37 T 13-10-2018 IPR031100 LOG family Astex_1256 0536f971041e6fd24ea874f360db3514 203 SUPERFAMILY SSF102405 12 188 6.87E-56 T 13-10-2018 Astex_1256 0536f971041e6fd24ea874f360db3514 203 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 15 188 1.5E-51 T 13-10-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG Astex_2314 e9d2cb3d2e574d7fb66511829ea3455d 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 3.9E-17 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_2314 e9d2cb3d2e574d7fb66511829ea3455d 302 Gene3D G3DSA:3.40.190.10 94 296 5.0E-64 T 13-10-2018 Astex_2314 e9d2cb3d2e574d7fb66511829ea3455d 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.0E-6 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_2314 e9d2cb3d2e574d7fb66511829ea3455d 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.0E-6 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_2314 e9d2cb3d2e574d7fb66511829ea3455d 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.0E-6 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_2314 e9d2cb3d2e574d7fb66511829ea3455d 302 Gene3D G3DSA:1.10.10.10 2 86 1.1E-23 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_2314 e9d2cb3d2e574d7fb66511829ea3455d 302 SUPERFAMILY SSF53850 90 301 4.16E-39 T 13-10-2018 Astex_2314 e9d2cb3d2e574d7fb66511829ea3455d 302 Gene3D G3DSA:3.40.190.10 163 274 5.0E-64 T 13-10-2018 Astex_2314 e9d2cb3d2e574d7fb66511829ea3455d 302 SUPERFAMILY SSF46785 2 112 1.53E-22 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_2314 e9d2cb3d2e574d7fb66511829ea3455d 302 Pfam PF03466 LysR substrate binding domain 90 300 1.7E-45 T 13-10-2018 IPR005119 LysR, substrate-binding Astex_3638 a98dcda0e9e8e7a9dd0e56ee5a2baadd 753 SUPERFAMILY SSF50960 62 447 1.44E-7 T 13-10-2018 Astex_3638 a98dcda0e9e8e7a9dd0e56ee5a2baadd 753 SUPERFAMILY SSF53474 485 749 5.65E-51 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_3638 a98dcda0e9e8e7a9dd0e56ee5a2baadd 753 Gene3D G3DSA:3.40.50.1820 475 752 1.3E-58 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_3638 a98dcda0e9e8e7a9dd0e56ee5a2baadd 753 Pfam PF00326 Prolyl oligopeptidase family 530 749 4.3E-34 T 13-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 Astex_0082 fa9139af6ac45e5de3bd3df66f2d21ef 1006 TIGRFAM TIGR02786 addB_alphas: double-strand break repair protein AddB 13 990 2.4E-259 T 13-10-2018 IPR014153 Double-strand break repair protein AddB Astex_0082 fa9139af6ac45e5de3bd3df66f2d21ef 1006 Pfam PF12705 PD-(D/E)XK nuclease superfamily 724 957 1.7E-15 T 13-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type Astex_0082 fa9139af6ac45e5de3bd3df66f2d21ef 1006 SUPERFAMILY SSF52540 345 672 1.14E-29 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2027 a28c388bdef4daf314ea700d946e5ede 293 SUPERFAMILY SSF53850 87 288 1.03E-24 T 13-10-2018 Astex_2027 a28c388bdef4daf314ea700d946e5ede 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 61 1.3E-21 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_2027 a28c388bdef4daf314ea700d946e5ede 293 Gene3D G3DSA:3.40.190.10 91 269 4.5E-28 T 13-10-2018 Astex_2027 a28c388bdef4daf314ea700d946e5ede 293 Pfam PF03466 LysR substrate binding domain 86 282 3.1E-27 T 13-10-2018 IPR005119 LysR, substrate-binding Astex_2027 a28c388bdef4daf314ea700d946e5ede 293 Gene3D G3DSA:3.40.190.10 164 261 4.5E-28 T 13-10-2018 Astex_2027 a28c388bdef4daf314ea700d946e5ede 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.4E-9 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_2027 a28c388bdef4daf314ea700d946e5ede 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.4E-9 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_2027 a28c388bdef4daf314ea700d946e5ede 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.4E-9 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_2027 a28c388bdef4daf314ea700d946e5ede 293 SUPERFAMILY SSF46785 2 85 1.02E-23 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_2027 a28c388bdef4daf314ea700d946e5ede 293 Gene3D G3DSA:1.10.10.10 1 86 1.9E-27 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_2353 1cd8fb364dc05d02f2d1e6621b7f0cd5 696 Pfam PF04539 Sigma-70 region 3 541 616 1.1E-29 T 13-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 Astex_2353 1cd8fb364dc05d02f2d1e6621b7f0cd5 696 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 13 695 44.767 T 13-10-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 Astex_2353 1cd8fb364dc05d02f2d1e6621b7f0cd5 696 Gene3D G3DSA:1.10.10.10 612 696 2.9E-36 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_2353 1cd8fb364dc05d02f2d1e6621b7f0cd5 696 Pfam PF04542 Sigma-70 region 2 462 531 2.0E-21 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 Astex_2353 1cd8fb364dc05d02f2d1e6621b7f0cd5 696 Pfam PF00140 Sigma-70 factor, region 1.2 108 140 1.6E-13 T 13-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Astex_2353 1cd8fb364dc05d02f2d1e6621b7f0cd5 696 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 655 681 - T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Astex_2353 1cd8fb364dc05d02f2d1e6621b7f0cd5 696 Gene3D G3DSA:1.10.601.10 123 531 3.4E-107 T 13-10-2018 Astex_2353 1cd8fb364dc05d02f2d1e6621b7f0cd5 696 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 458 694 7.8E-120 T 13-10-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 Astex_2353 1cd8fb364dc05d02f2d1e6621b7f0cd5 696 Gene3D G3DSA:1.10.10.10 535 610 2.0E-32 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_2353 1cd8fb364dc05d02f2d1e6621b7f0cd5 696 SUPERFAMILY SSF88946 125 529 3.92E-93 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 Astex_2353 1cd8fb364dc05d02f2d1e6621b7f0cd5 696 Pfam PF03979 Sigma-70 factor, region 1.1 22 81 1.4E-19 T 13-10-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 Astex_2353 1cd8fb364dc05d02f2d1e6621b7f0cd5 696 PRINTS PR00046 Major sigma-70 factor signature 486 499 7.1E-31 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Astex_2353 1cd8fb364dc05d02f2d1e6621b7f0cd5 696 PRINTS PR00046 Major sigma-70 factor signature 634 646 7.1E-31 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Astex_2353 1cd8fb364dc05d02f2d1e6621b7f0cd5 696 PRINTS PR00046 Major sigma-70 factor signature 655 670 7.1E-31 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Astex_2353 1cd8fb364dc05d02f2d1e6621b7f0cd5 696 PRINTS PR00046 Major sigma-70 factor signature 670 681 7.1E-31 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Astex_2353 1cd8fb364dc05d02f2d1e6621b7f0cd5 696 PRINTS PR00046 Major sigma-70 factor signature 510 518 7.1E-31 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Astex_2353 1cd8fb364dc05d02f2d1e6621b7f0cd5 696 Pfam PF04546 Sigma-70, non-essential region 152 430 4.7E-37 T 13-10-2018 IPR007631 RNA polymerase sigma factor 70, non-essential domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Astex_2353 1cd8fb364dc05d02f2d1e6621b7f0cd5 696 Pfam PF04545 Sigma-70, region 4 630 683 1.8E-18 T 13-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 Astex_2353 1cd8fb364dc05d02f2d1e6621b7f0cd5 696 SUPERFAMILY SSF88659 592 694 4.71E-26 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Astex_2353 1cd8fb364dc05d02f2d1e6621b7f0cd5 696 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 459 683 1.1E-38 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 Astex_2353 1cd8fb364dc05d02f2d1e6621b7f0cd5 696 SUPERFAMILY SSF88659 535 608 3.53E-21 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Astex_2353 1cd8fb364dc05d02f2d1e6621b7f0cd5 696 Gene3D G3DSA:1.10.220.120 22 81 2.1E-18 T 13-10-2018 Astex_2353 1cd8fb364dc05d02f2d1e6621b7f0cd5 696 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 486 499 - T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 Astex_2154 05261657f3e405f82195173e3dc274d0 98 SMART SM00530 12 67 4.4E-11 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Astex_2154 05261657f3e405f82195173e3dc274d0 98 Gene3D G3DSA:1.10.260.40 2 75 5.2E-15 T 13-10-2018 Astex_2154 05261657f3e405f82195173e3dc274d0 98 Pfam PF13560 Helix-turn-helix domain 8 63 9.7E-14 T 13-10-2018 Astex_2154 05261657f3e405f82195173e3dc274d0 98 SUPERFAMILY SSF47413 6 64 1.15E-13 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Astex_1289 63e9c84628c264d901d2b9f590bbaa5d 303 Pfam PF10670 Domain of unknown function (DUF4198) 23 249 8.5E-57 T 13-10-2018 IPR019613 Protein of unknown function DUF4198 Astex_1649 0300a7bb9226a35918a72fbb3532d171 241 Pfam PF00072 Response regulator receiver domain 14 123 3.4E-28 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1649 0300a7bb9226a35918a72fbb3532d171 241 SMART SM00448 12 122 5.4E-44 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1649 0300a7bb9226a35918a72fbb3532d171 241 Gene3D G3DSA:1.10.10.10 133 241 4.9E-31 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1649 0300a7bb9226a35918a72fbb3532d171 241 SUPERFAMILY SSF46894 132 238 7.65E-25 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Astex_1649 0300a7bb9226a35918a72fbb3532d171 241 SUPERFAMILY SSF52172 6 130 4.41E-40 T 13-10-2018 IPR011006 CheY-like superfamily Astex_1649 0300a7bb9226a35918a72fbb3532d171 241 Gene3D G3DSA:3.40.50.2300 2 132 3.4E-36 T 13-10-2018 Astex_1649 0300a7bb9226a35918a72fbb3532d171 241 SMART SM00862 160 237 2.4E-25 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Astex_1649 0300a7bb9226a35918a72fbb3532d171 241 Pfam PF00486 Transcriptional regulatory protein, C terminal 162 237 2.7E-23 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Astex_2869 9387768540573a286f15c27671e4bc31 290 Pfam PF01063 Amino-transferase class IV 32 257 2.8E-46 T 13-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 Astex_2869 9387768540573a286f15c27671e4bc31 290 Gene3D G3DSA:3.30.470.10 1 120 1.9E-31 T 13-10-2018 Astex_2869 9387768540573a286f15c27671e4bc31 290 Gene3D G3DSA:3.20.10.10 123 286 2.9E-48 T 13-10-2018 Astex_2869 9387768540573a286f15c27671e4bc31 290 ProSitePatterns PS00770 Aminotransferases class-IV signature. 182 212 - T 13-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 Astex_2869 9387768540573a286f15c27671e4bc31 290 SUPERFAMILY SSF56752 1 280 1.57E-73 T 13-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 Astex_0994 3919fc1dd5fce1da39e374fb6c949580 849 SUPERFAMILY SSF56935 33 849 5.49E-110 T 13-10-2018 Astex_0994 3919fc1dd5fce1da39e374fb6c949580 849 Pfam PF00593 TonB dependent receptor 305 848 2.7E-43 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_0994 3919fc1dd5fce1da39e374fb6c949580 849 Pfam PF07715 TonB-dependent Receptor Plug Domain 58 166 8.5E-15 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_0994 3919fc1dd5fce1da39e374fb6c949580 849 Gene3D G3DSA:2.40.170.20 50 849 2.1E-127 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_0469 8ca5bd474b66d5472e2c44be1b3660f7 526 Gene3D G3DSA:3.30.565.10 363 525 1.6E-36 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_0469 8ca5bd474b66d5472e2c44be1b3660f7 526 Pfam PF00672 HAMP domain 238 288 8.5E-8 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Astex_0469 8ca5bd474b66d5472e2c44be1b3660f7 526 SMART SM00388 293 358 7.6E-14 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_0469 8ca5bd474b66d5472e2c44be1b3660f7 526 Pfam PF13756 Stimulus-sensing domain 99 179 1.4E-7 T 13-10-2018 IPR025919 Stimulus-sensing domain Astex_0469 8ca5bd474b66d5472e2c44be1b3660f7 526 SMART SM00387 404 525 1.5E-32 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_0469 8ca5bd474b66d5472e2c44be1b3660f7 526 SUPERFAMILY SSF158472 238 290 1.31E-5 T 13-10-2018 Astex_0469 8ca5bd474b66d5472e2c44be1b3660f7 526 SUPERFAMILY SSF55874 348 523 2.62E-36 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_0469 8ca5bd474b66d5472e2c44be1b3660f7 526 Gene3D G3DSA:1.20.1480.50 200 298 9.1E-7 T 13-10-2018 Astex_0469 8ca5bd474b66d5472e2c44be1b3660f7 526 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 405 522 1.3E-18 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_0469 8ca5bd474b66d5472e2c44be1b3660f7 526 Pfam PF13755 Sensor N-terminal transmembrane domain 21 78 5.4E-16 T 13-10-2018 IPR025908 Sensor N-terminal transmembrane domain Astex_0469 8ca5bd474b66d5472e2c44be1b3660f7 526 Gene3D G3DSA:1.10.287.130 299 354 1.1E-11 T 13-10-2018 Astex_0469 8ca5bd474b66d5472e2c44be1b3660f7 526 Pfam PF00512 His Kinase A (phospho-acceptor) domain 295 357 3.2E-13 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_0469 8ca5bd474b66d5472e2c44be1b3660f7 526 PRINTS PR00344 Bacterial sensor protein C-terminal signature 463 473 2.3E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_0469 8ca5bd474b66d5472e2c44be1b3660f7 526 PRINTS PR00344 Bacterial sensor protein C-terminal signature 509 522 2.3E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_0469 8ca5bd474b66d5472e2c44be1b3660f7 526 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 459 2.3E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_0469 8ca5bd474b66d5472e2c44be1b3660f7 526 PRINTS PR00344 Bacterial sensor protein C-terminal signature 480 498 2.3E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_0469 8ca5bd474b66d5472e2c44be1b3660f7 526 SMART SM00304 237 292 1.1E-7 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Astex_0469 8ca5bd474b66d5472e2c44be1b3660f7 526 SUPERFAMILY SSF47384 276 357 2.16E-16 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Astex_2297 eb7e616057bf85112db7f73437633414 191 SUPERFAMILY SSF46894 5 71 6.46E-17 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Astex_2297 eb7e616057bf85112db7f73437633414 191 SMART SM00421 8 65 9.5E-13 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Astex_2297 eb7e616057bf85112db7f73437633414 191 Pfam PF00196 Bacterial regulatory proteins, luxR family 11 59 5.6E-13 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Astex_2297 eb7e616057bf85112db7f73437633414 191 Gene3D G3DSA:1.10.10.10 1 79 3.8E-16 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_2297 eb7e616057bf85112db7f73437633414 191 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 41 53 3.2E-10 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Astex_2297 eb7e616057bf85112db7f73437633414 191 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 25 41 3.2E-10 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Astex_2297 eb7e616057bf85112db7f73437633414 191 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 11 25 3.2E-10 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Astex_1680 83156d7cc3fac31b8e7903ffb9331a01 436 Hamap MF_00671 Tol-Pal system protein TolB [tolB]. 15 431 46.444 T 13-10-2018 IPR014167 Tol-Pal system protein TolB GO:0017038|GO:0042597 Astex_1680 83156d7cc3fac31b8e7903ffb9331a01 436 Gene3D G3DSA:2.120.10.30 169 436 7.5E-80 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like Astex_1680 83156d7cc3fac31b8e7903ffb9331a01 436 Pfam PF07676 WD40-like Beta Propeller Repeat 374 404 4.4E-5 T 13-10-2018 IPR011659 WD40-like Beta Propeller Astex_1680 83156d7cc3fac31b8e7903ffb9331a01 436 Pfam PF07676 WD40-like Beta Propeller Repeat 330 363 1.6E-4 T 13-10-2018 IPR011659 WD40-like Beta Propeller Astex_1680 83156d7cc3fac31b8e7903ffb9331a01 436 Pfam PF07676 WD40-like Beta Propeller Repeat 251 277 1.1E-6 T 13-10-2018 IPR011659 WD40-like Beta Propeller Astex_1680 83156d7cc3fac31b8e7903ffb9331a01 436 Pfam PF07676 WD40-like Beta Propeller Repeat 286 320 2.0E-13 T 13-10-2018 IPR011659 WD40-like Beta Propeller Astex_1680 83156d7cc3fac31b8e7903ffb9331a01 436 Gene3D G3DSA:3.40.50.10070 26 168 6.3E-37 T 13-10-2018 IPR036752 TolB, N-terminal domain superfamily GO:0015031|GO:0042597 Astex_1680 83156d7cc3fac31b8e7903ffb9331a01 436 TIGRFAM TIGR02800 propeller_TolB: Tol-Pal system beta propeller repeat protein TolB 24 432 1.7E-141 T 13-10-2018 IPR014167 Tol-Pal system protein TolB GO:0017038|GO:0042597 Astex_1680 83156d7cc3fac31b8e7903ffb9331a01 436 SUPERFAMILY SSF52964 36 165 2.48E-39 T 13-10-2018 Astex_1680 83156d7cc3fac31b8e7903ffb9331a01 436 SUPERFAMILY SSF69304 158 433 6.28E-62 T 13-10-2018 Astex_1680 83156d7cc3fac31b8e7903ffb9331a01 436 Pfam PF04052 TolB amino-terminal domain 33 133 4.5E-27 T 13-10-2018 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 Astex_0843 af5b5ba5eab163e4d074d5cbc2c03da7 269 Pfam PF16252 Domain of unknown function (DUF4908) 42 262 7.9E-115 T 13-10-2018 IPR032591 Protein of unknown function DUF4908 Astex_1584 90090c36dd3288a508bd2b8f9d5aef93 260 Pfam PF10988 Putative auto-transporter adhesin, head GIN domain 73 244 2.3E-28 T 13-10-2018 IPR021255 Putative auto-transporter adhesin, head GIN domain Astex_1584 90090c36dd3288a508bd2b8f9d5aef93 260 Gene3D G3DSA:2.160.20.120 60 259 4.8E-32 T 13-10-2018 Astex_1346 492b1c0b477ddfcee69af0c0b18d71d3 255 SUPERFAMILY SSF52172 132 253 1.27E-26 T 13-10-2018 IPR011006 CheY-like superfamily Astex_1346 492b1c0b477ddfcee69af0c0b18d71d3 255 Gene3D G3DSA:3.40.50.2300 5 126 1.5E-17 T 13-10-2018 Astex_1346 492b1c0b477ddfcee69af0c0b18d71d3 255 Pfam PF00072 Response regulator receiver domain 136 247 1.7E-18 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1346 492b1c0b477ddfcee69af0c0b18d71d3 255 Pfam PF00072 Response regulator receiver domain 7 119 5.1E-11 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1346 492b1c0b477ddfcee69af0c0b18d71d3 255 SUPERFAMILY SSF52172 7 123 8.4E-19 T 13-10-2018 IPR011006 CheY-like superfamily Astex_1346 492b1c0b477ddfcee69af0c0b18d71d3 255 SMART SM00448 133 249 1.2E-17 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1346 492b1c0b477ddfcee69af0c0b18d71d3 255 SMART SM00448 4 119 4.4E-7 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1346 492b1c0b477ddfcee69af0c0b18d71d3 255 Gene3D G3DSA:3.40.50.2300 127 255 2.5E-25 T 13-10-2018 Astex_3783 9184f03b879fcfdabf8f55b294a5603d 93 Pfam PF07178 TraL protein 3 92 3.4E-27 T 13-10-2018 IPR009838 Type IV conjugative transfer system, protein TraL GO:0000746|GO:0019867 Astex_3783 9184f03b879fcfdabf8f55b294a5603d 93 TIGRFAM TIGR02762 TraL_TIGR: type IV conjugative transfer system protein TraL 4 92 2.4E-21 T 13-10-2018 IPR009838 Type IV conjugative transfer system, protein TraL GO:0000746|GO:0019867 Astex_0698 68f85f6c7d3aeb02b4137469b6b9a185 679 Gene3D G3DSA:3.40.50.620 148 552 1.5E-59 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Astex_0698 68f85f6c7d3aeb02b4137469b6b9a185 679 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 162 173 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Astex_0698 68f85f6c7d3aeb02b4137469b6b9a185 679 PRINTS PR01038 Arginyl-tRNA synthetase signature 169 185 8.5E-10 T 13-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 Astex_0698 68f85f6c7d3aeb02b4137469b6b9a185 679 PRINTS PR01038 Arginyl-tRNA synthetase signature 154 169 8.5E-10 T 13-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 Astex_0698 68f85f6c7d3aeb02b4137469b6b9a185 679 PRINTS PR01038 Arginyl-tRNA synthetase signature 193 206 8.5E-10 T 13-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 Astex_0698 68f85f6c7d3aeb02b4137469b6b9a185 679 Gene3D G3DSA:1.10.730.10 560 679 5.1E-16 T 13-10-2018 Astex_0698 68f85f6c7d3aeb02b4137469b6b9a185 679 Pfam PF05746 DALR anticodon binding domain 565 678 8.4E-17 T 13-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 Astex_0698 68f85f6c7d3aeb02b4137469b6b9a185 679 SMART SM00836 565 679 7.3E-18 T 13-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 Astex_0698 68f85f6c7d3aeb02b4137469b6b9a185 679 Pfam PF00750 tRNA synthetases class I (R) 153 343 1.3E-20 T 13-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 Astex_0698 68f85f6c7d3aeb02b4137469b6b9a185 679 Pfam PF00750 tRNA synthetases class I (R) 388 537 5.1E-13 T 13-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 Astex_0698 68f85f6c7d3aeb02b4137469b6b9a185 679 SUPERFAMILY SSF47323 561 678 6.41E-19 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Astex_0698 68f85f6c7d3aeb02b4137469b6b9a185 679 SUPERFAMILY SSF52374 153 543 4.22E-41 T 13-10-2018 Astex_1228 99cbc0aa361cf3199065b7b38f51624e 780 Pfam PF00326 Prolyl oligopeptidase family 566 762 9.0E-50 T 13-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 Astex_1228 99cbc0aa361cf3199065b7b38f51624e 780 Gene3D G3DSA:2.140.10.30 120 485 6.5E-80 T 13-10-2018 IPR038554 Dipeptidylpeptidase IV, N-terminal domain superfamily Astex_1228 99cbc0aa361cf3199065b7b38f51624e 780 Pfam PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region 170 469 2.6E-57 T 13-10-2018 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 Astex_1228 99cbc0aa361cf3199065b7b38f51624e 780 Gene3D G3DSA:3.40.50.1820 499 758 6.5E-49 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1228 99cbc0aa361cf3199065b7b38f51624e 780 SUPERFAMILY SSF82171 43 496 1.31E-42 T 13-10-2018 Astex_1228 99cbc0aa361cf3199065b7b38f51624e 780 SUPERFAMILY SSF53474 501 761 2.68E-53 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_2529 f2314e2635334a422f65381d4af98857 464 Gene3D G3DSA:3.50.50.60 27 362 4.0E-38 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_2529 f2314e2635334a422f65381d4af98857 464 SUPERFAMILY SSF51905 37 403 3.49E-26 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_2529 f2314e2635334a422f65381d4af98857 464 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 39 247 2.1E-21 T 13-10-2018 Astex_2529 f2314e2635334a422f65381d4af98857 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 214 232 4.8E-5 T 13-10-2018 Astex_2529 f2314e2635334a422f65381d4af98857 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 38 57 4.8E-5 T 13-10-2018 Astex_2529 f2314e2635334a422f65381d4af98857 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 214 239 1.0E-5 T 13-10-2018 Astex_2529 f2314e2635334a422f65381d4af98857 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 37 59 1.0E-5 T 13-10-2018 Astex_2529 f2314e2635334a422f65381d4af98857 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 172 181 1.0E-5 T 13-10-2018 Astex_1315 68a960a13a5c414f50788946a64f1431 431 Pfam PF09492 Pectic acid lyase 161 419 2.9E-81 T 13-10-2018 IPR012669 Pectic acid lyase Astex_1315 68a960a13a5c414f50788946a64f1431 431 SUPERFAMILY SSF81853 49 428 1.96E-79 T 13-10-2018 Astex_1315 68a960a13a5c414f50788946a64f1431 431 TIGRFAM TIGR02474 pec_lyase: pectate lyase 118 419 2.7E-94 T 13-10-2018 IPR012669 Pectic acid lyase Astex_1315 68a960a13a5c414f50788946a64f1431 431 Gene3D G3DSA:1.50.10.20 24 430 2.4E-136 T 13-10-2018 Astex_2886 749c75e74c6efd93d96e029058b0572e 688 Pfam PF00270 DEAD/DEAH box helicase 282 402 9.4E-14 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Astex_2886 749c75e74c6efd93d96e029058b0572e 688 SUPERFAMILY SSF52540 310 586 6.56E-48 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2886 749c75e74c6efd93d96e029058b0572e 688 SMART SM00487 258 448 4.6E-26 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Astex_2886 749c75e74c6efd93d96e029058b0572e 688 SMART SM00490 493 576 4.0E-19 T 13-10-2018 IPR001650 Helicase, C-terminal Astex_2886 749c75e74c6efd93d96e029058b0572e 688 Gene3D G3DSA:3.40.50.300 208 438 3.4E-75 T 13-10-2018 Astex_2886 749c75e74c6efd93d96e029058b0572e 688 Gene3D G3DSA:3.40.50.300 446 617 1.8E-48 T 13-10-2018 Astex_2886 749c75e74c6efd93d96e029058b0572e 688 Pfam PF00271 Helicase conserved C-terminal domain 471 575 1.9E-15 T 13-10-2018 IPR001650 Helicase, C-terminal Astex_2886 749c75e74c6efd93d96e029058b0572e 688 SUPERFAMILY SSF50249 6 173 1.88E-17 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Astex_2886 749c75e74c6efd93d96e029058b0572e 688 Gene3D G3DSA:2.40.50.140 49 140 2.2E-8 T 13-10-2018 Astex_0609 5f51abb4298c44700ac616bd82fd6e32 120 SUPERFAMILY SSF141488 48 117 1.57E-11 T 13-10-2018 IPR036328 C-type lysozyme inhibitor superfamily Astex_0609 5f51abb4298c44700ac616bd82fd6e32 120 Pfam PF09864 Membrane-bound lysozyme-inhibitor of c-type lysozyme 51 114 7.5E-13 T 13-10-2018 IPR018660 C-type lysozyme inhibitor Astex_0609 5f51abb4298c44700ac616bd82fd6e32 120 Gene3D G3DSA:2.40.128.200 47 120 2.0E-13 T 13-10-2018 IPR036328 C-type lysozyme inhibitor superfamily Astex_2455 d97b6d599cbcb9239a1c59d30f28fd6f 175 Gene3D G3DSA:2.10.109.10 51 175 9.9E-11 T 13-10-2018 Astex_2455 d97b6d599cbcb9239a1c59d30f28fd6f 175 Pfam PF10502 Signal peptidase, peptidase S26 40 175 1.4E-45 T 13-10-2018 IPR019533 Peptidase S26 Astex_2455 d97b6d599cbcb9239a1c59d30f28fd6f 175 SUPERFAMILY SSF51306 42 174 2.88E-25 T 13-10-2018 IPR036286 LexA/Signal peptidase-like superfamily Astex_1047 b7e8df540fcc313eaec9a1d7cbaef5a9 419 SUPERFAMILY SSF110087 279 411 5.23E-31 T 13-10-2018 IPR036182 Copper chaperone PCuAC superfamily Astex_1047 b7e8df540fcc313eaec9a1d7cbaef5a9 419 Gene3D G3DSA:2.60.40.1890 299 414 9.5E-28 T 13-10-2018 IPR036182 Copper chaperone PCuAC superfamily Astex_1047 b7e8df540fcc313eaec9a1d7cbaef5a9 419 Pfam PF05425 Copper resistance protein D 167 265 5.0E-19 T 13-10-2018 IPR008457 Copper resistance protein D GO:0016021 Astex_1047 b7e8df540fcc313eaec9a1d7cbaef5a9 419 Pfam PF04314 Copper chaperone PCu(A)C 295 403 3.3E-28 T 13-10-2018 IPR007410 Copper chaperone PCuAC Astex_0162 69751f1d42069dfb4fdcdf21a181a3b2 223 Gene3D G3DSA:3.30.420.40 100 182 1.1E-33 T 13-10-2018 Astex_0162 69751f1d42069dfb4fdcdf21a181a3b2 223 Gene3D G3DSA:3.30.420.40 6 209 1.1E-33 T 13-10-2018 Astex_0162 69751f1d42069dfb4fdcdf21a181a3b2 223 SUPERFAMILY SSF53067 5 106 2.81E-19 T 13-10-2018 Astex_0162 69751f1d42069dfb4fdcdf21a181a3b2 223 Pfam PF00814 Glycoprotease family 35 129 3.0E-20 T 13-10-2018 IPR000905 Gcp-like domain Astex_0162 69751f1d42069dfb4fdcdf21a181a3b2 223 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 6 208 2.5E-37 T 13-10-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 Astex_0557 5e4c8f135679f6590dc993b9ffa45944 206 SMART SM00421 142 199 1.1E-19 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Astex_0557 5e4c8f135679f6590dc993b9ffa45944 206 Pfam PF00196 Bacterial regulatory proteins, luxR family 144 198 2.1E-18 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Astex_0557 5e4c8f135679f6590dc993b9ffa45944 206 SUPERFAMILY SSF52172 9 175 4.13E-34 T 13-10-2018 IPR011006 CheY-like superfamily Astex_0557 5e4c8f135679f6590dc993b9ffa45944 206 Gene3D G3DSA:3.40.50.2300 4 134 2.4E-43 T 13-10-2018 Astex_0557 5e4c8f135679f6590dc993b9ffa45944 206 SMART SM00448 7 118 2.0E-27 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_0557 5e4c8f135679f6590dc993b9ffa45944 206 Gene3D G3DSA:1.10.10.10 137 199 8.7E-18 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_0557 5e4c8f135679f6590dc993b9ffa45944 206 Pfam PF00072 Response regulator receiver domain 9 119 4.5E-28 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_0557 5e4c8f135679f6590dc993b9ffa45944 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 187 2.4E-11 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Astex_0557 5e4c8f135679f6590dc993b9ffa45944 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 175 2.4E-11 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Astex_0557 5e4c8f135679f6590dc993b9ffa45944 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 145 159 2.4E-11 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Astex_0557 5e4c8f135679f6590dc993b9ffa45944 206 ProSitePatterns PS00622 LuxR-type HTH domain signature. 159 186 - T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Astex_3408 9c9ecd0b53922bcf17a268c07eb5adeb 458 SUPERFAMILY SSF118215 24 417 1.57E-113 T 13-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 Astex_3408 9c9ecd0b53922bcf17a268c07eb5adeb 458 Pfam PF00375 Sodium:dicarboxylate symporter family 24 416 9.8E-104 T 13-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Astex_3408 9c9ecd0b53922bcf17a268c07eb5adeb 458 Hamap MF_01300 C4-dicarboxylate transport protein [dctA]. 17 443 36.96 T 13-10-2018 IPR023954 C4-dicarboxylate transport protein GO:0006835|GO:0015293|GO:0016021 Astex_3408 9c9ecd0b53922bcf17a268c07eb5adeb 458 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 310 333 - T 13-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site Astex_3408 9c9ecd0b53922bcf17a268c07eb5adeb 458 Gene3D G3DSA:1.10.3860.10 14 431 8.9E-117 T 13-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 Astex_3408 9c9ecd0b53922bcf17a268c07eb5adeb 458 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 51 66 - T 13-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site Astex_3408 9c9ecd0b53922bcf17a268c07eb5adeb 458 PRINTS PR00173 Glutamate-aspartate symporter signature 342 361 6.1E-20 T 13-10-2018 Astex_3408 9c9ecd0b53922bcf17a268c07eb5adeb 458 PRINTS PR00173 Glutamate-aspartate symporter signature 160 182 6.1E-20 T 13-10-2018 Astex_3408 9c9ecd0b53922bcf17a268c07eb5adeb 458 PRINTS PR00173 Glutamate-aspartate symporter signature 307 333 6.1E-20 T 13-10-2018 Astex_3408 9c9ecd0b53922bcf17a268c07eb5adeb 458 PRINTS PR00173 Glutamate-aspartate symporter signature 22 42 6.1E-20 T 13-10-2018 Astex_3408 9c9ecd0b53922bcf17a268c07eb5adeb 458 PRINTS PR00173 Glutamate-aspartate symporter signature 89 114 6.1E-20 T 13-10-2018 Astex_1828 a9c7595cd784d2d43713e689488babad 658 Gene3D G3DSA:2.70.98.90 72 356 3.4E-40 T 13-10-2018 IPR038221 YidC, periplasmic domain superfamily Astex_1828 a9c7595cd784d2d43713e689488babad 658 Pfam PF14849 YidC periplasmic domain 75 369 2.2E-84 T 13-10-2018 IPR038210 Membrane insertase YidC, periplasmic domain Astex_1828 a9c7595cd784d2d43713e689488babad 658 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 380 588 1.9E-67 T 13-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_1828 a9c7595cd784d2d43713e689488babad 658 PRINTS PR01900 YidC translocation/secretion protein signature 366 382 6.5E-19 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 Astex_1828 a9c7595cd784d2d43713e689488babad 658 PRINTS PR01900 YidC translocation/secretion protein signature 543 567 6.5E-19 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 Astex_1828 a9c7595cd784d2d43713e689488babad 658 PRINTS PR01900 YidC translocation/secretion protein signature 524 539 6.5E-19 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 Astex_1828 a9c7595cd784d2d43713e689488babad 658 TIGRFAM TIGR03593 yidC_nterm: membrane protein insertase, YidC/Oxa1 family, N-terminal domain 6 379 1.1E-84 T 13-10-2018 IPR028053 Membrane insertase YidC, N-terminal Astex_1828 a9c7595cd784d2d43713e689488babad 658 PRINTS PR00701 60kDa inner membrane protein signature 4 25 1.3E-16 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 Astex_1828 a9c7595cd784d2d43713e689488babad 658 PRINTS PR00701 60kDa inner membrane protein signature 81 102 1.3E-16 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 Astex_1828 a9c7595cd784d2d43713e689488babad 658 PRINTS PR00701 60kDa inner membrane protein signature 351 371 1.3E-16 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 Astex_1828 a9c7595cd784d2d43713e689488babad 658 PRINTS PR00701 60kDa inner membrane protein signature 442 465 1.3E-16 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 Astex_1828 a9c7595cd784d2d43713e689488babad 658 Pfam PF02096 60Kd inner membrane protein 381 588 1.9E-57 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 Astex_1828 a9c7595cd784d2d43713e689488babad 658 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 7 590 21.732 T 13-10-2018 IPR019998 Membrane insertase YidC GO:0016021|GO:0032977 Astex_3184 6bb0e7c74e331990879491b312392f73 120 TIGRFAM TIGR04433 UrcA_uranyl: UrcA family protein 3 88 4.8E-21 T 13-10-2018 IPR030972 UrcA family protein Astex_0579 106a9eb03e6a409ee0b7b38c89e4e2ca 557 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 42 331 1.3E-64 T 13-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 Astex_0579 106a9eb03e6a409ee0b7b38c89e4e2ca 557 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 43 555 9.1E-88 T 13-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 Astex_0579 106a9eb03e6a409ee0b7b38c89e4e2ca 557 Gene3D G3DSA:1.10.10.350 442 557 2.8E-9 T 13-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 Astex_0579 106a9eb03e6a409ee0b7b38c89e4e2ca 557 PRINTS PR00987 Glutamyl-tRNA synthetase signature 45 57 4.8E-16 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Astex_0579 106a9eb03e6a409ee0b7b38c89e4e2ca 557 PRINTS PR00987 Glutamyl-tRNA synthetase signature 255 263 4.8E-16 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Astex_0579 106a9eb03e6a409ee0b7b38c89e4e2ca 557 PRINTS PR00987 Glutamyl-tRNA synthetase signature 239 249 4.8E-16 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Astex_0579 106a9eb03e6a409ee0b7b38c89e4e2ca 557 PRINTS PR00987 Glutamyl-tRNA synthetase signature 74 87 4.8E-16 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 Astex_0579 106a9eb03e6a409ee0b7b38c89e4e2ca 557 Gene3D G3DSA:3.40.50.620 35 381 6.9E-101 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Astex_0579 106a9eb03e6a409ee0b7b38c89e4e2ca 557 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 33 557 23.14 T 13-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 Astex_0579 106a9eb03e6a409ee0b7b38c89e4e2ca 557 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 48 59 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Astex_0579 106a9eb03e6a409ee0b7b38c89e4e2ca 557 SUPERFAMILY SSF52374 42 335 8.58E-75 T 13-10-2018 Astex_0579 106a9eb03e6a409ee0b7b38c89e4e2ca 557 SUPERFAMILY SSF48163 367 556 5.89E-17 T 13-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 Astex_0287 996a1e5ba6c3c865a6c7762d1a7c211c 625 Pfam PF02867 Ribonucleotide reductase, barrel domain 442 587 5.9E-34 T 13-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Astex_0287 996a1e5ba6c3c865a6c7762d1a7c211c 625 SUPERFAMILY SSF51998 112 592 1.13E-133 T 13-10-2018 Astex_0287 996a1e5ba6c3c865a6c7762d1a7c211c 625 Pfam PF02867 Ribonucleotide reductase, barrel domain 114 431 1.4E-72 T 13-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Astex_0287 996a1e5ba6c3c865a6c7762d1a7c211c 625 Gene3D G3DSA:3.20.70.20 21 598 1.3E-171 T 13-10-2018 Astex_0287 996a1e5ba6c3c865a6c7762d1a7c211c 625 PRINTS PR01183 Ribonucleotide reductase large chain signature 405 428 1.2E-18 T 13-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Astex_0287 996a1e5ba6c3c865a6c7762d1a7c211c 625 PRINTS PR01183 Ribonucleotide reductase large chain signature 298 309 1.2E-18 T 13-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Astex_0287 996a1e5ba6c3c865a6c7762d1a7c211c 625 PRINTS PR01183 Ribonucleotide reductase large chain signature 187 206 1.2E-18 T 13-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Astex_0287 996a1e5ba6c3c865a6c7762d1a7c211c 625 PRINTS PR01183 Ribonucleotide reductase large chain signature 377 399 1.2E-18 T 13-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Astex_0287 996a1e5ba6c3c865a6c7762d1a7c211c 625 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 45 110 1.7E-15 T 13-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Astex_0287 996a1e5ba6c3c865a6c7762d1a7c211c 625 SUPERFAMILY SSF48168 39 109 9.55E-16 T 13-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Astex_0438 701e93c4afc040c7d74ba042a1ff1783 241 PRINTS PR00604 Class IA and IB cytochrome C signature 147 157 9.1E-15 T 13-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_0438 701e93c4afc040c7d74ba042a1ff1783 241 PRINTS PR00604 Class IA and IB cytochrome C signature 95 110 9.1E-15 T 13-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_0438 701e93c4afc040c7d74ba042a1ff1783 241 PRINTS PR00604 Class IA and IB cytochrome C signature 82 89 9.1E-15 T 13-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_0438 701e93c4afc040c7d74ba042a1ff1783 241 PRINTS PR00604 Class IA and IB cytochrome C signature 111 121 9.1E-15 T 13-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_0438 701e93c4afc040c7d74ba042a1ff1783 241 PRINTS PR00604 Class IA and IB cytochrome C signature 164 172 9.1E-15 T 13-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_0438 701e93c4afc040c7d74ba042a1ff1783 241 PRINTS PR00604 Class IA and IB cytochrome C signature 128 144 9.1E-15 T 13-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_0438 701e93c4afc040c7d74ba042a1ff1783 241 Gene3D G3DSA:1.10.760.10 35 173 1.2E-39 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Astex_0438 701e93c4afc040c7d74ba042a1ff1783 241 Pfam PF00034 Cytochrome c 74 172 1.4E-6 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_0438 701e93c4afc040c7d74ba042a1ff1783 241 SUPERFAMILY SSF46626 70 173 5.07E-31 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Astex_0787 b2ea3cdb106a04362e752383f2000578 228 Gene3D G3DSA:1.20.1050.10 84 193 3.7E-50 T 13-10-2018 Astex_0787 b2ea3cdb106a04362e752383f2000578 228 Gene3D G3DSA:3.40.30.10 7 197 3.7E-50 T 13-10-2018 Astex_0787 b2ea3cdb106a04362e752383f2000578 228 SUPERFAMILY SSF52833 4 80 9.24E-14 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Astex_0787 b2ea3cdb106a04362e752383f2000578 228 SUPERFAMILY SSF47616 81 199 1.32E-16 T 13-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily Astex_0787 b2ea3cdb106a04362e752383f2000578 228 Pfam PF13417 Glutathione S-transferase, N-terminal domain 10 80 8.3E-10 T 13-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 Astex_2132 31e73150a6ed1a6e8357d170f0483320 287 SUPERFAMILY SSF51182 9 271 7.54E-96 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily Astex_2132 31e73150a6ed1a6e8357d170f0483320 287 Gene3D G3DSA:2.60.120.520 37 153 4.6E-112 T 13-10-2018 IPR027449 5-keto-4-deoxyuronate isomerase, N-terminal KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 Astex_2132 31e73150a6ed1a6e8357d170f0483320 287 Hamap MF_00687 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase [kduI]. 8 287 51.552 T 13-10-2018 IPR007045 5-keto 4-deoxyuronate isomerase GO:0008697|GO:0045490 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 Astex_2132 31e73150a6ed1a6e8357d170f0483320 287 Gene3D G3DSA:2.60.120.10 18 272 4.6E-112 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Astex_2132 31e73150a6ed1a6e8357d170f0483320 287 PIRSF PIRSF006625 8 287 2.3E-126 T 13-10-2018 IPR007045 5-keto 4-deoxyuronate isomerase GO:0008697|GO:0045490 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 Astex_2132 31e73150a6ed1a6e8357d170f0483320 287 Pfam PF04962 KduI/IolB family 64 274 9.6E-35 T 13-10-2018 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 Astex_1079 60ed13f3dbfbdcfa2e3de9a480356c4c 740 SUPERFAMILY SSF48179 637 728 2.81E-20 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Astex_1079 60ed13f3dbfbdcfa2e3de9a480356c4c 740 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 513 608 2.5E-19 T 13-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 Astex_1079 60ed13f3dbfbdcfa2e3de9a480356c4c 740 Gene3D G3DSA:3.90.226.10 1 323 8.6E-92 T 13-10-2018 Astex_1079 60ed13f3dbfbdcfa2e3de9a480356c4c 740 Gene3D G3DSA:1.10.1040.50 513 718 1.3E-59 T 13-10-2018 Astex_1079 60ed13f3dbfbdcfa2e3de9a480356c4c 740 SUPERFAMILY SSF52096 2 310 5.67E-65 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Astex_1079 60ed13f3dbfbdcfa2e3de9a480356c4c 740 SUPERFAMILY SSF48179 513 612 1.79E-22 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Astex_1079 60ed13f3dbfbdcfa2e3de9a480356c4c 740 SUPERFAMILY SSF51735 324 510 1.53E-49 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_1079 60ed13f3dbfbdcfa2e3de9a480356c4c 740 Gene3D G3DSA:3.40.50.720 325 511 3.9E-58 T 13-10-2018 Astex_1079 60ed13f3dbfbdcfa2e3de9a480356c4c 740 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 326 509 3.1E-55 T 13-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 Astex_1079 60ed13f3dbfbdcfa2e3de9a480356c4c 740 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 209 4.1E-36 T 13-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 Astex_0397 5c0130cbadb54a876ec61474adc77e9a 163 Pfam PF02590 Predicted SPOUT methyltransferase 1 161 3.7E-40 T 13-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 Astex_0397 5c0130cbadb54a876ec61474adc77e9a 163 PIRSF PIRSF004505 1 162 4.9E-39 T 13-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 Astex_0397 5c0130cbadb54a876ec61474adc77e9a 163 Gene3D G3DSA:3.40.1280.10 1 162 7.2E-41 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Astex_0397 5c0130cbadb54a876ec61474adc77e9a 163 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 162 24.386 T 13-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 Astex_0397 5c0130cbadb54a876ec61474adc77e9a 163 SUPERFAMILY SSF75217 1 160 6.54E-38 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases Astex_0992 7d4c4483345dd8f99431455b7ccbab2f 477 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 11 462 2.9E-128 T 13-10-2018 IPR003846 Uncharacterised protein family UPF0061 Astex_2642 8775b2b4a44dd37b5e234eac15d5699f 168 Gene3D G3DSA:3.40.630.30 1 168 1.7E-44 T 13-10-2018 Astex_2642 8775b2b4a44dd37b5e234eac15d5699f 168 SUPERFAMILY SSF55729 1 152 1.56E-33 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Astex_2642 8775b2b4a44dd37b5e234eac15d5699f 168 Pfam PF13302 Acetyltransferase (GNAT) domain 6 148 5.3E-24 T 13-10-2018 IPR000182 GNAT domain Astex_3015 b965b20adf71e08e4a922ead9eb8e94e 593 Pfam PF00152 tRNA synthetases class II (D, K and N) 122 560 2.3E-96 T 13-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Astex_3015 b965b20adf71e08e4a922ead9eb8e94e 593 Pfam PF01336 OB-fold nucleic acid binding domain 21 104 1.4E-15 T 13-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 Astex_3015 b965b20adf71e08e4a922ead9eb8e94e 593 Pfam PF02938 GAD domain 320 405 9.1E-6 T 13-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 Astex_3015 b965b20adf71e08e4a922ead9eb8e94e 593 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 4 587 30.291 T 13-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 Astex_3015 b965b20adf71e08e4a922ead9eb8e94e 593 PRINTS PR01042 Aspartyl-tRNA synthetase signature 194 206 2.7E-22 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Astex_3015 b965b20adf71e08e4a922ead9eb8e94e 593 PRINTS PR01042 Aspartyl-tRNA synthetase signature 211 224 2.7E-22 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Astex_3015 b965b20adf71e08e4a922ead9eb8e94e 593 PRINTS PR01042 Aspartyl-tRNA synthetase signature 477 493 2.7E-22 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Astex_3015 b965b20adf71e08e4a922ead9eb8e94e 593 PRINTS PR01042 Aspartyl-tRNA synthetase signature 521 535 2.7E-22 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Astex_3015 b965b20adf71e08e4a922ead9eb8e94e 593 Gene3D G3DSA:3.30.1360.30 278 422 1.4E-167 T 13-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 Astex_3015 b965b20adf71e08e4a922ead9eb8e94e 593 SUPERFAMILY SSF55681 115 586 8.42E-101 T 13-10-2018 Astex_3015 b965b20adf71e08e4a922ead9eb8e94e 593 SUPERFAMILY SSF50249 4 107 2.57E-31 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Astex_3015 b965b20adf71e08e4a922ead9eb8e94e 593 SUPERFAMILY SSF55261 295 422 1.74E-33 T 13-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 Astex_3015 b965b20adf71e08e4a922ead9eb8e94e 593 Gene3D G3DSA:2.40.50.140 1 107 3.6E-37 T 13-10-2018 Astex_3015 b965b20adf71e08e4a922ead9eb8e94e 593 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 5 585 7.6E-186 T 13-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 Astex_3015 b965b20adf71e08e4a922ead9eb8e94e 593 Gene3D G3DSA:3.30.930.10 121 585 1.4E-167 T 13-10-2018 Astex_1298 629781b95d2c35c42e64862e80a74487 506 Gene3D G3DSA:1.10.10.1710 438 505 1.4E-24 T 13-10-2018 Astex_1298 629781b95d2c35c42e64862e80a74487 506 Gene3D G3DSA:3.40.50.620 6 224 1.1E-116 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Astex_1298 629781b95d2c35c42e64862e80a74487 506 Gene3D G3DSA:1.10.579.10 317 437 1.4E-53 T 13-10-2018 Astex_1298 629781b95d2c35c42e64862e80a74487 506 SUPERFAMILY SSF48173 224 484 3.53E-57 T 13-10-2018 IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily Reactome: R-HSA-400253 Astex_1298 629781b95d2c35c42e64862e80a74487 506 Pfam PF04244 Deoxyribodipyrimidine photo-lyase-related protein 5 222 1.6E-76 T 13-10-2018 IPR007357 Deoxyribodipyrimidine photolyase-related protein Astex_1298 629781b95d2c35c42e64862e80a74487 506 Gene3D G3DSA:1.25.40.80 127 313 1.1E-116 T 13-10-2018 Astex_2516 1061965029f25056d327161ad5c3b6de 479 Gene3D G3DSA:3.40.50.2000 22 451 1.2E-160 T 13-10-2018 Astex_2516 1061965029f25056d327161ad5c3b6de 479 SUPERFAMILY SSF53756 2 455 1.38E-138 T 13-10-2018 Astex_2516 1061965029f25056d327161ad5c3b6de 479 Pfam PF00982 Glycosyltransferase family 20 20 455 2.8E-133 T 13-10-2018 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 KEGG: 00500+2.4.1.15 Astex_2516 1061965029f25056d327161ad5c3b6de 479 Gene3D G3DSA:3.40.50.2000 232 440 1.2E-160 T 13-10-2018 Astex_2516 1061965029f25056d327161ad5c3b6de 479 TIGRFAM TIGR02400 trehalose_OtsA: alpha,alpha-trehalose-phosphate synthase (UDP-forming) 3 455 1.1E-172 T 13-10-2018 IPR012766 Alpha,alpha-trehalose-phosphate synthase GO:0003825|GO:0005992 KEGG: 00500+2.4.1.15 Astex_0840 4fedaddaacf5d2ce9b24cd271f4531b2 229 TIGRFAM TIGR01848 PHA_reg_PhaR: polyhydroxyalkanoate synthesis repressor PhaR 36 141 3.7E-46 T 13-10-2018 IPR010134 Polyhydroxyalkanoate synthesis repressor PhaR GO:0006355 Astex_0840 4fedaddaacf5d2ce9b24cd271f4531b2 229 Pfam PF07879 PHB/PHA accumulation regulator DNA-binding domain 36 95 9.1E-29 T 13-10-2018 IPR012909 PHA accumulation regulator DNA-binding, N-terminal Astex_0840 4fedaddaacf5d2ce9b24cd271f4531b2 229 Pfam PF05233 PHB accumulation regulatory domain 100 139 1.0E-17 T 13-10-2018 IPR007897 PHB accumulation regulatory Astex_2989 c0fdfd18471d10e9acca654dc2066ee8 1394 Pfam PF04997 RNA polymerase Rpb1, domain 1 18 344 4.3E-87 T 13-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Astex_2989 c0fdfd18471d10e9acca654dc2066ee8 1394 Gene3D G3DSA:2.40.50.100 1017 1118 1.0E-27 T 13-10-2018 Astex_2989 c0fdfd18471d10e9acca654dc2066ee8 1394 Gene3D G3DSA:1.10.40.90 376 418 1.2E-20 T 13-10-2018 Astex_2989 c0fdfd18471d10e9acca654dc2066ee8 1394 Pfam PF04998 RNA polymerase Rpb1, domain 5 762 1268 7.8E-73 T 13-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Astex_2989 c0fdfd18471d10e9acca654dc2066ee8 1394 Gene3D G3DSA:1.10.132.30 641 786 2.0E-62 T 13-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Astex_2989 c0fdfd18471d10e9acca654dc2066ee8 1394 Pfam PF04983 RNA polymerase Rpb1, domain 3 491 644 5.4E-25 T 13-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Astex_2989 c0fdfd18471d10e9acca654dc2066ee8 1394 Gene3D G3DSA:2.40.50.100 1143 1207 3.6E-65 T 13-10-2018 Astex_2989 c0fdfd18471d10e9acca654dc2066ee8 1394 Gene3D G3DSA:1.10.1790.20 1127 1306 3.6E-65 T 13-10-2018 Astex_2989 c0fdfd18471d10e9acca654dc2066ee8 1394 Gene3D G3DSA:1.10.150.390 1308 1368 4.1E-26 T 13-10-2018 Astex_2989 c0fdfd18471d10e9acca654dc2066ee8 1394 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 20 1016 0.0 T 13-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Astex_2989 c0fdfd18471d10e9acca654dc2066ee8 1394 Gene3D G3DSA:2.40.50.100 943 1016 3.9E-19 T 13-10-2018 Astex_2989 c0fdfd18471d10e9acca654dc2066ee8 1394 Pfam PF05000 RNA polymerase Rpb1, domain 4 673 759 7.0E-18 T 13-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Astex_2989 c0fdfd18471d10e9acca654dc2066ee8 1394 Gene3D G3DSA:1.10.274.100 561 640 3.0E-12 T 13-10-2018 Astex_2989 c0fdfd18471d10e9acca654dc2066ee8 1394 Gene3D G3DSA:1.10.274.100 492 560 6.2E-22 T 13-10-2018 Astex_2989 c0fdfd18471d10e9acca654dc2066ee8 1394 Pfam PF00623 RNA polymerase Rpb1, domain 2 346 487 2.0E-36 T 13-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Astex_2989 c0fdfd18471d10e9acca654dc2066ee8 1394 SMART SM00663 237 516 1.3E-182 T 13-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Astex_2989 c0fdfd18471d10e9acca654dc2066ee8 1394 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 14 1369 18.654 T 13-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Astex_2989 c0fdfd18471d10e9acca654dc2066ee8 1394 SUPERFAMILY SSF64484 18 1356 0.0 T 13-10-2018 Astex_0649 ce316dcdfb1d332d17add4ac30fc4768 335 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 50 327 2.9E-35 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 Astex_0649 ce316dcdfb1d332d17add4ac30fc4768 335 Gene3D G3DSA:2.40.420.20 51 328 5.1E-36 T 13-10-2018 Astex_0649 ce316dcdfb1d332d17add4ac30fc4768 335 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 73 243 1.6E-13 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain Astex_0649 ce316dcdfb1d332d17add4ac30fc4768 335 Gene3D G3DSA:2.40.50.100 70 201 5.1E-36 T 13-10-2018 Astex_0649 ce316dcdfb1d332d17add4ac30fc4768 335 Gene3D G3DSA:1.10.287.470 104 162 5.1E-36 T 13-10-2018 Astex_0649 ce316dcdfb1d332d17add4ac30fc4768 335 SUPERFAMILY SSF111369 64 214 1.31E-17 T 13-10-2018 Astex_0649 ce316dcdfb1d332d17add4ac30fc4768 335 Gene3D G3DSA:2.40.30.170 55 271 5.1E-36 T 13-10-2018 Astex_3059 ecbdd6c27699f4c354bea75bac8dfddd 198 Hamap MF_01207 Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ [msrQ]. 4 197 21.212 T 13-10-2018 IPR022837 Protein-methionine-sulfoxide reductase subunit MsrQ GO:0005887|GO:0030091 Astex_3059 ecbdd6c27699f4c354bea75bac8dfddd 198 Pfam PF01794 Ferric reductase like transmembrane component 46 160 1.3E-17 T 13-10-2018 IPR013130 Ferric reductase transmembrane component-like domain Astex_0728 c1271bbfaae1a70dbb4bca1ea3df18c0 382 SMART SM00327 199 359 0.0036 T 13-10-2018 IPR002035 von Willebrand factor, type A Astex_0728 c1271bbfaae1a70dbb4bca1ea3df18c0 382 Pfam PF05762 VWA domain containing CoxE-like protein 138 356 4.7E-57 T 13-10-2018 IPR008912 Uncharacterised protein family CoxE-like Astex_0728 c1271bbfaae1a70dbb4bca1ea3df18c0 382 SUPERFAMILY SSF53300 202 359 3.84E-21 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Astex_0728 c1271bbfaae1a70dbb4bca1ea3df18c0 382 Gene3D G3DSA:3.40.50.410 201 344 1.8E-7 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Astex_2954 64f0184ab6c24fc6553d8e46a35c2106 213 PIRSF PIRSF033239 2 210 5.5E-56 T 13-10-2018 IPR010331 Exopolysaccharide synthesis, ExoD Astex_2954 64f0184ab6c24fc6553d8e46a35c2106 213 Pfam PF06055 Exopolysaccharide synthesis, ExoD 14 195 1.9E-53 T 13-10-2018 IPR010331 Exopolysaccharide synthesis, ExoD Astex_1874 2faf9f6e87596d7104faf13ae5c4a36e 715 Pfam PF03781 Sulfatase-modifying factor enzyme 1 190 339 3.1E-22 T 13-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 Astex_1874 2faf9f6e87596d7104faf13ae5c4a36e 715 SUPERFAMILY SSF53335 432 700 1.15E-11 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Astex_1874 2faf9f6e87596d7104faf13ae5c4a36e 715 TIGRFAM TIGR03440 egtB_TIGR03440: ergothioneine biosynthesis protein EgtB 23 402 3.7E-149 T 13-10-2018 IPR017806 Ergothioneine biosynthesis protein EgtB GO:0052699 KEGG: 00340+1.14.99.50|MetaCyc: PWY-7255 Astex_1874 2faf9f6e87596d7104faf13ae5c4a36e 715 Gene3D G3DSA:3.40.50.150 442 614 6.8E-47 T 13-10-2018 Astex_1874 2faf9f6e87596d7104faf13ae5c4a36e 715 Pfam PF12867 DinB superfamily 27 155 2.3E-9 T 13-10-2018 IPR024775 DinB-like domain Astex_1874 2faf9f6e87596d7104faf13ae5c4a36e 715 SUPERFAMILY SSF56436 189 404 1.73E-60 T 13-10-2018 IPR016187 C-type lectin fold Astex_1874 2faf9f6e87596d7104faf13ae5c4a36e 715 Pfam PF10017 Histidine-specific methyltransferase, SAM-dependent 416 714 6.8E-106 T 13-10-2018 IPR019257 Histidine-specific methyltransferase, SAM-dependent Astex_1874 2faf9f6e87596d7104faf13ae5c4a36e 715 Gene3D G3DSA:3.90.1580.10 177 331 3.5E-27 T 13-10-2018 Astex_1874 2faf9f6e87596d7104faf13ae5c4a36e 715 TIGRFAM TIGR03438 egtD_ergothio: dimethylhistidine N-methyltransferase 415 713 5.9E-119 T 13-10-2018 IPR035094 Histidine N-alpha-methyltransferase KEGG: 00340+2.1.1.44|MetaCyc: PWY-7255|MetaCyc: PWY-7550 Astex_3586 c07a04d66a7e7b264b81a3f692457d87 675 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 296 350 - T 13-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_3586 c07a04d66a7e7b264b81a3f692457d87 675 TIGRFAM TIGR02843 CyoB: cytochrome o ubiquinol oxidase, subunit I 18 663 0.0 T 13-10-2018 IPR014207 Cytochrome o ubiquinol oxidase, subunit I GO:0016682|GO:0055114 MetaCyc: PWY-7544 Astex_3586 c07a04d66a7e7b264b81a3f692457d87 675 PRINTS PR01165 Cytochrome c oxidase subunit I signature 63 88 5.9E-92 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_3586 c07a04d66a7e7b264b81a3f692457d87 675 PRINTS PR01165 Cytochrome c oxidase subunit I signature 140 164 5.9E-92 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_3586 c07a04d66a7e7b264b81a3f692457d87 675 PRINTS PR01165 Cytochrome c oxidase subunit I signature 427 446 5.9E-92 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_3586 c07a04d66a7e7b264b81a3f692457d87 675 PRINTS PR01165 Cytochrome c oxidase subunit I signature 477 498 5.9E-92 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_3586 c07a04d66a7e7b264b81a3f692457d87 675 PRINTS PR01165 Cytochrome c oxidase subunit I signature 182 194 5.9E-92 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_3586 c07a04d66a7e7b264b81a3f692457d87 675 PRINTS PR01165 Cytochrome c oxidase subunit I signature 399 417 5.9E-92 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_3586 c07a04d66a7e7b264b81a3f692457d87 675 PRINTS PR01165 Cytochrome c oxidase subunit I signature 113 136 5.9E-92 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_3586 c07a04d66a7e7b264b81a3f692457d87 675 PRINTS PR01165 Cytochrome c oxidase subunit I signature 364 385 5.9E-92 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_3586 c07a04d66a7e7b264b81a3f692457d87 675 PRINTS PR01165 Cytochrome c oxidase subunit I signature 294 315 5.9E-92 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_3586 c07a04d66a7e7b264b81a3f692457d87 675 PRINTS PR01165 Cytochrome c oxidase subunit I signature 214 232 5.9E-92 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_3586 c07a04d66a7e7b264b81a3f692457d87 675 PRINTS PR01165 Cytochrome c oxidase subunit I signature 243 262 5.9E-92 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_3586 c07a04d66a7e7b264b81a3f692457d87 675 PRINTS PR01165 Cytochrome c oxidase subunit I signature 340 355 5.9E-92 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_3586 c07a04d66a7e7b264b81a3f692457d87 675 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 72 520 2.4E-134 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_3586 c07a04d66a7e7b264b81a3f692457d87 675 Gene3D G3DSA:1.20.210.10 47 582 3.1E-187 T 13-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_3586 c07a04d66a7e7b264b81a3f692457d87 675 SUPERFAMILY SSF81442 59 575 4.58E-173 T 13-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_0962 bf3d91b6441d529475a5d0922e9e5313 191 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 174 34.997 T 13-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 Astex_0962 bf3d91b6441d529475a5d0922e9e5313 191 Gene3D G3DSA:3.30.160.20 12 82 2.5E-30 T 13-10-2018 Astex_0962 bf3d91b6441d529475a5d0922e9e5313 191 Gene3D G3DSA:3.30.230.10 86 178 3.8E-32 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Astex_0962 bf3d91b6441d529475a5d0922e9e5313 191 Pfam PF03719 Ribosomal protein S5, C-terminal domain 98 168 2.6E-29 T 13-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 Astex_0962 bf3d91b6441d529475a5d0922e9e5313 191 SUPERFAMILY SSF54768 19 86 2.3E-22 T 13-10-2018 Astex_0962 bf3d91b6441d529475a5d0922e9e5313 191 SUPERFAMILY SSF54211 90 170 1.01E-24 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Astex_0962 bf3d91b6441d529475a5d0922e9e5313 191 ProSitePatterns PS00585 Ribosomal protein S5 signature. 38 70 - T 13-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site Astex_0962 bf3d91b6441d529475a5d0922e9e5313 191 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 19 173 5.4E-64 T 13-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 Astex_0962 bf3d91b6441d529475a5d0922e9e5313 191 Pfam PF00333 Ribosomal protein S5, N-terminal domain 22 85 1.0E-28 T 13-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 Astex_2187 0b0ea575041d63d8b48fd2bf3bdd466f 422 SUPERFAMILY SSF56935 99 397 4.94E-6 T 13-10-2018 Astex_2187 0b0ea575041d63d8b48fd2bf3bdd466f 422 Pfam PF10082 Putative beta-barrel porin 2 41 420 2.7E-108 T 13-10-2018 IPR018759 Putative beta-barrel porin 2 Astex_3697 d21d91e59b847e22fc3bdf67649d2ac5 275 SUPERFAMILY SSF51658 27 236 6.75E-7 T 13-10-2018 IPR036237 Xylose isomerase-like superfamily Astex_3697 d21d91e59b847e22fc3bdf67649d2ac5 275 Pfam PF05114 Protein of unknown function (DUF692) 3 268 1.6E-93 T 13-10-2018 IPR007801 Uncharacterised protein family UPF0276 Astex_3697 d21d91e59b847e22fc3bdf67649d2ac5 275 Gene3D G3DSA:3.20.20.150 1 274 5.1E-80 T 13-10-2018 Astex_2612 d86f4ba7dcabd1a80db2f446b9fb69ee 627 Pfam PF00854 POT family 176 399 3.5E-42 T 13-10-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-427975 Astex_2612 d86f4ba7dcabd1a80db2f446b9fb69ee 627 Pfam PF00854 POT family 438 568 4.1E-18 T 13-10-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-427975 Astex_2612 d86f4ba7dcabd1a80db2f446b9fb69ee 627 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 195 398 4.2E-42 T 13-10-2018 IPR005279 Dipeptide/tripeptide permease GO:0015833|GO:0016020|GO:1904680 Astex_2612 d86f4ba7dcabd1a80db2f446b9fb69ee 627 ProSitePatterns PS01022 PTR2 family proton/oligopeptide symporters signature 1. 85 109 - T 13-10-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 Astex_2612 d86f4ba7dcabd1a80db2f446b9fb69ee 627 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 235 247 - T 13-10-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 Astex_2612 d86f4ba7dcabd1a80db2f446b9fb69ee 627 SUPERFAMILY SSF103473 22 609 1.09E-18 T 13-10-2018 IPR036259 MFS transporter superfamily Astex_0585 e41be247695a790c4e969ef1b58f1403 402 Gene3D G3DSA:2.40.30.10 308 400 5.9E-16 T 13-10-2018 Astex_0585 e41be247695a790c4e969ef1b58f1403 402 Gene3D G3DSA:2.30.30.280 248 307 3.6E-16 T 13-10-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 Astex_0585 e41be247695a790c4e969ef1b58f1403 402 Pfam PF03054 tRNA methyl transferase 36 392 2.1E-113 T 13-10-2018 Astex_0585 e41be247695a790c4e969ef1b58f1403 402 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 36 392 1.5E-99 T 13-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 Astex_0585 e41be247695a790c4e969ef1b58f1403 402 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 35 393 39.192 T 13-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 Astex_0585 e41be247695a790c4e969ef1b58f1403 402 SUPERFAMILY SSF52402 34 277 1.26E-49 T 13-10-2018 Astex_0585 e41be247695a790c4e969ef1b58f1403 402 Gene3D G3DSA:3.40.50.620 21 243 2.2E-73 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Astex_1552 33e3375cbdcf49b324ea4270e5ff59da 218 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 34 206 2.3E-31 T 13-10-2018 IPR003740 Uncharacterised membrane protein YitT Astex_1283 30ffece748b001b7f373f004d323e2ab 1054 Pfam PF03797 Autotransporter beta-domain 786 1010 2.3E-18 T 13-10-2018 IPR005546 Autotransporter beta-domain Astex_1283 30ffece748b001b7f373f004d323e2ab 1054 Gene3D G3DSA:2.40.128.130 763 1054 2.5E-24 T 13-10-2018 IPR036709 Autotransporter beta-domain superfamily Astex_1283 30ffece748b001b7f373f004d323e2ab 1054 SMART SM00869 782 1044 1.7E-8 T 13-10-2018 IPR005546 Autotransporter beta-domain Astex_1283 30ffece748b001b7f373f004d323e2ab 1054 SUPERFAMILY SSF103515 778 1054 1.29E-21 T 13-10-2018 IPR036709 Autotransporter beta-domain superfamily Astex_2019 934f4fb2be0d87f4c845047228769794 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 216 4.3E-23 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Astex_2019 934f4fb2be0d87f4c845047228769794 226 SMART SM00448 1 112 4.5E-41 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_2019 934f4fb2be0d87f4c845047228769794 226 SUPERFAMILY SSF52172 1 178 6.45E-39 T 13-10-2018 IPR011006 CheY-like superfamily Astex_2019 934f4fb2be0d87f4c845047228769794 226 Pfam PF00072 Response regulator receiver domain 3 112 7.3E-27 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_2019 934f4fb2be0d87f4c845047228769794 226 Gene3D G3DSA:3.40.50.2300 1 119 1.6E-41 T 13-10-2018 Astex_2019 934f4fb2be0d87f4c845047228769794 226 SMART SM00862 145 216 4.0E-26 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Astex_2019 934f4fb2be0d87f4c845047228769794 226 Gene3D G3DSA:1.10.10.10 120 217 4.2E-28 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_0242 e1d3f8231447ea946d73f182fe618134 469 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 331 6.6E-71 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Astex_0242 e1d3f8231447ea946d73f182fe618134 469 Gene3D G3DSA:3.50.50.60 8 330 3.4E-119 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_0242 e1d3f8231447ea946d73f182fe618134 469 SUPERFAMILY SSF55424 346 465 3.61E-41 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 Astex_0242 e1d3f8231447ea946d73f182fe618134 469 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 7 464 1.9E-163 T 13-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 Astex_0242 e1d3f8231447ea946d73f182fe618134 469 PIRSF PIRSF000350 1 464 8.0E-90 T 13-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 Astex_0242 e1d3f8231447ea946d73f182fe618134 469 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 179 197 9.3E-37 T 13-10-2018 Astex_0242 e1d3f8231447ea946d73f182fe618134 469 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 140 158 9.3E-37 T 13-10-2018 Astex_0242 e1d3f8231447ea946d73f182fe618134 469 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 296 318 9.3E-37 T 13-10-2018 Astex_0242 e1d3f8231447ea946d73f182fe618134 469 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 268 284 9.3E-37 T 13-10-2018 Astex_0242 e1d3f8231447ea946d73f182fe618134 469 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 9.3E-37 T 13-10-2018 Astex_0242 e1d3f8231447ea946d73f182fe618134 469 Gene3D G3DSA:3.50.50.60 152 275 3.4E-119 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_0242 e1d3f8231447ea946d73f182fe618134 469 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 42 52 - T 13-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 Astex_0242 e1d3f8231447ea946d73f182fe618134 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 8 30 1.8E-78 T 13-10-2018 Astex_0242 e1d3f8231447ea946d73f182fe618134 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 346 367 1.8E-78 T 13-10-2018 Astex_0242 e1d3f8231447ea946d73f182fe618134 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 152 1.8E-78 T 13-10-2018 Astex_0242 e1d3f8231447ea946d73f182fe618134 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 41 56 1.8E-78 T 13-10-2018 Astex_0242 e1d3f8231447ea946d73f182fe618134 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 433 453 1.8E-78 T 13-10-2018 Astex_0242 e1d3f8231447ea946d73f182fe618134 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 179 204 1.8E-78 T 13-10-2018 Astex_0242 e1d3f8231447ea946d73f182fe618134 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 311 318 1.8E-78 T 13-10-2018 Astex_0242 e1d3f8231447ea946d73f182fe618134 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 411 426 1.8E-78 T 13-10-2018 Astex_0242 e1d3f8231447ea946d73f182fe618134 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 269 283 1.8E-78 T 13-10-2018 Astex_0242 e1d3f8231447ea946d73f182fe618134 469 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 350 458 4.3E-38 T 13-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 Astex_0242 e1d3f8231447ea946d73f182fe618134 469 SUPERFAMILY SSF51905 4 370 8.21E-63 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_0242 e1d3f8231447ea946d73f182fe618134 469 Gene3D G3DSA:3.30.390.30 349 468 1.7E-44 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 Astex_2590 6e01eb10e0f6731a17bf8d6478f4b044 671 Pfam PF14509 Glycosyl-hydrolase 97 C-terminal, oligomerisation 568 658 4.2E-27 T 13-10-2018 IPR029483 Glycosyl-hydrolase 97, C-terminal oligomerisation domain Astex_2590 6e01eb10e0f6731a17bf8d6478f4b044 671 Gene3D G3DSA:3.20.20.70 289 566 1.7E-102 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_2590 6e01eb10e0f6731a17bf8d6478f4b044 671 Gene3D G3DSA:2.60.40.1180 568 658 4.0E-27 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta Astex_2590 6e01eb10e0f6731a17bf8d6478f4b044 671 Gene3D G3DSA:2.70.98.10 16 288 7.8E-58 T 13-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 Astex_2590 6e01eb10e0f6731a17bf8d6478f4b044 671 Pfam PF14508 Glycosyl-hydrolase 97 N-terminal 29 286 2.7E-51 T 13-10-2018 IPR029486 Glycosyl-hydrolase 97, N-terminal domain Astex_2590 6e01eb10e0f6731a17bf8d6478f4b044 671 Pfam PF10566 Glycoside hydrolase 97 294 565 1.7E-100 T 13-10-2018 IPR019563 Glycosyl-hydrolase 97, catalytic domain Astex_2590 6e01eb10e0f6731a17bf8d6478f4b044 671 SUPERFAMILY SSF51445 304 549 2.43E-24 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_2726 b5aba74e43aed42d9fa436ebd3851e1a 476 SUPERFAMILY SSF48208 42 470 5.1E-164 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 Astex_2726 b5aba74e43aed42d9fa436ebd3851e1a 476 SMART SM01149 64 467 4.4E-243 T 13-10-2018 IPR008313 Metal-independent alpha-mannosidase Astex_2726 b5aba74e43aed42d9fa436ebd3851e1a 476 Pfam PF06824 Metal-independent alpha-mannosidase (GH125) 65 466 2.7E-153 T 13-10-2018 IPR008313 Metal-independent alpha-mannosidase Astex_2726 b5aba74e43aed42d9fa436ebd3851e1a 476 Gene3D G3DSA:1.50.10.10 48 476 1.4E-168 T 13-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 Astex_2726 b5aba74e43aed42d9fa436ebd3851e1a 476 PIRSF PIRSF028846 42 476 9.0E-173 T 13-10-2018 IPR008313 Metal-independent alpha-mannosidase Astex_1340 fcce63b3607760dd771075e4d699c75a 543 SUPERFAMILY SSF49503 144 357 2.75E-47 T 13-10-2018 IPR008972 Cupredoxin Astex_1340 fcce63b3607760dd771075e4d699c75a 543 ProSitePatterns PS00079 Multicopper oxidases signature 1. 492 512 - T 13-10-2018 IPR033138 Multicopper oxidases, conserved site Astex_1340 fcce63b3607760dd771075e4d699c75a 543 Pfam PF00394 Multicopper oxidase 150 318 1.2E-26 T 13-10-2018 IPR001117 Multicopper oxidase, type 1 GO:0055114 Astex_1340 fcce63b3607760dd771075e4d699c75a 543 Gene3D G3DSA:2.60.40.420 148 353 5.1E-36 T 13-10-2018 IPR008972 Cupredoxin Astex_1340 fcce63b3607760dd771075e4d699c75a 543 Pfam PF07731 Multicopper oxidase 406 515 4.9E-25 T 13-10-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 Astex_1340 fcce63b3607760dd771075e4d699c75a 543 ProSitePatterns PS00079 Multicopper oxidases signature 1. 115 135 - T 13-10-2018 IPR033138 Multicopper oxidases, conserved site Astex_1340 fcce63b3607760dd771075e4d699c75a 543 ProSitePatterns PS00080 Multicopper oxidases signature 2. 497 508 - T 13-10-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 Astex_1340 fcce63b3607760dd771075e4d699c75a 543 Pfam PF07732 Multicopper oxidase 37 140 5.0E-34 T 13-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 Astex_1340 fcce63b3607760dd771075e4d699c75a 543 SUPERFAMILY SSF49503 15 162 3.88E-38 T 13-10-2018 IPR008972 Cupredoxin Astex_1340 fcce63b3607760dd771075e4d699c75a 543 SUPERFAMILY SSF49503 381 518 6.11E-34 T 13-10-2018 IPR008972 Cupredoxin Astex_1340 fcce63b3607760dd771075e4d699c75a 543 Gene3D G3DSA:2.60.40.420 12 139 7.0E-37 T 13-10-2018 IPR008972 Cupredoxin Astex_1340 fcce63b3607760dd771075e4d699c75a 543 Gene3D G3DSA:2.60.40.420 382 518 4.9E-33 T 13-10-2018 IPR008972 Cupredoxin Astex_1645 fa28a8524aa748ed5bb2c3911554a9ba 69 PIRSF PIRSF002599 1 69 1.9E-23 T 13-10-2018 IPR012156 Cold shock, CspA GO:0003676 Astex_1645 fa28a8524aa748ed5bb2c3911554a9ba 69 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 13-10-2018 IPR019844 Cold-shock conserved site Astex_1645 fa28a8524aa748ed5bb2c3911554a9ba 69 SMART SM00357 3 69 1.2E-27 T 13-10-2018 IPR011129 Cold shock domain GO:0003676 Astex_1645 fa28a8524aa748ed5bb2c3911554a9ba 69 PRINTS PR00050 Cold shock protein signature 25 34 6.3E-14 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Astex_1645 fa28a8524aa748ed5bb2c3911554a9ba 69 PRINTS PR00050 Cold shock protein signature 40 58 6.3E-14 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Astex_1645 fa28a8524aa748ed5bb2c3911554a9ba 69 PRINTS PR00050 Cold shock protein signature 4 19 6.3E-14 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Astex_1645 fa28a8524aa748ed5bb2c3911554a9ba 69 SUPERFAMILY SSF50249 1 68 2.57E-24 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Astex_1645 fa28a8524aa748ed5bb2c3911554a9ba 69 Gene3D G3DSA:2.40.50.140 1 69 9.4E-27 T 13-10-2018 Astex_1645 fa28a8524aa748ed5bb2c3911554a9ba 69 Pfam PF00313 'Cold-shock' DNA-binding domain 3 67 2.2E-25 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 Astex_3462 5f31642c963689b30763b4c7d2da303b 192 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 122 128 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 Astex_3462 5f31642c963689b30763b4c7d2da303b 192 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 185 3.1E-45 T 13-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 Astex_3462 5f31642c963689b30763b4c7d2da303b 192 SUPERFAMILY SSF53335 1 179 5.53E-42 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Astex_3462 5f31642c963689b30763b4c7d2da303b 192 PIRSF PIRSF004553 1 187 6.5E-51 T 13-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 Astex_3462 5f31642c963689b30763b4c7d2da303b 192 Pfam PF03602 Conserved hypothetical protein 95 1 184 6.5E-56 T 13-10-2018 Astex_3462 5f31642c963689b30763b4c7d2da303b 192 Gene3D G3DSA:3.40.50.150 1 190 2.7E-57 T 13-10-2018 Astex_1111 1cf97ba0fb5efaae93b1746cd95ee0aa 503 Gene3D G3DSA:1.25.60.10 62 184 1.2E-18 T 13-10-2018 IPR038076 MgtE, N-terminal domain superfamily Astex_1111 1cf97ba0fb5efaae93b1746cd95ee0aa 503 SUPERFAMILY SSF161093 331 502 2.22E-45 T 13-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 Astex_1111 1cf97ba0fb5efaae93b1746cd95ee0aa 503 TIGRFAM TIGR00400 mgtE: magnesium transporter 80 502 4.0E-87 T 13-10-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 Astex_1111 1cf97ba0fb5efaae93b1746cd95ee0aa 503 Pfam PF00571 CBS domain 272 308 8.5E-4 T 13-10-2018 IPR000644 CBS domain Astex_1111 1cf97ba0fb5efaae93b1746cd95ee0aa 503 Gene3D G3DSA:3.10.580.10 186 313 6.8E-33 T 13-10-2018 Astex_1111 1cf97ba0fb5efaae93b1746cd95ee0aa 503 SUPERFAMILY SSF54631 189 326 6.03E-24 T 13-10-2018 Astex_1111 1cf97ba0fb5efaae93b1746cd95ee0aa 503 Gene3D G3DSA:1.10.357.20 328 502 9.0E-50 T 13-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain Astex_1111 1cf97ba0fb5efaae93b1746cd95ee0aa 503 SMART SM00116 261 309 2.2E-4 T 13-10-2018 IPR000644 CBS domain Astex_1111 1cf97ba0fb5efaae93b1746cd95ee0aa 503 SMART SM00924 87 190 1.9E-28 T 13-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain Astex_1111 1cf97ba0fb5efaae93b1746cd95ee0aa 503 SUPERFAMILY SSF158791 61 187 9.16E-27 T 13-10-2018 Astex_1111 1cf97ba0fb5efaae93b1746cd95ee0aa 503 Pfam PF03448 MgtE intracellular N domain 87 188 2.5E-23 T 13-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain Astex_1111 1cf97ba0fb5efaae93b1746cd95ee0aa 503 Pfam PF01769 Divalent cation transporter 374 495 2.4E-23 T 13-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 Astex_0540 07a65187c807cbcc01ca42d675717c88 690 Pfam PF04185 Phosphoesterase family 43 443 1.5E-104 T 13-10-2018 IPR007312 Phosphoesterase GO:0016788 Astex_0540 07a65187c807cbcc01ca42d675717c88 690 Pfam PF05506 Domain of unknown function (DUF756) 512 595 3.5E-22 T 13-10-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 Astex_0540 07a65187c807cbcc01ca42d675717c88 690 Pfam PF05506 Domain of unknown function (DUF756) 606 677 6.0E-6 T 13-10-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 Astex_0540 07a65187c807cbcc01ca42d675717c88 690 TIGRFAM TIGR03396 PC_PLC: phospholipase C, phosphocholine-specific 4 689 1.4E-250 T 13-10-2018 IPR017767 Bacterial phospholipase C, phosphocholine-specific GO:0034480 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 Astex_0540 07a65187c807cbcc01ca42d675717c88 690 Gene3D G3DSA:3.40.720.10 275 493 2.4E-45 T 13-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 Astex_0540 07a65187c807cbcc01ca42d675717c88 690 Gene3D G3DSA:3.40.720.10 33 201 1.7E-28 T 13-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 Astex_0212 3575c4ef07cc3ae80f237be026cc296d 106 ProSitePatterns PS00814 Adrenodoxin family, iron-sulfur binding region signature. 40 50 - T 13-10-2018 IPR018298 Adrenodoxin, iron-sulphur binding site GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 Astex_0212 3575c4ef07cc3ae80f237be026cc296d 106 SUPERFAMILY SSF54292 3 104 2.69E-33 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 Astex_0212 3575c4ef07cc3ae80f237be026cc296d 106 PRINTS PR00355 Adrenodoxin signature 59 73 2.3E-7 T 13-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 Astex_0212 3575c4ef07cc3ae80f237be026cc296d 106 PRINTS PR00355 Adrenodoxin signature 82 90 2.3E-7 T 13-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 Astex_0212 3575c4ef07cc3ae80f237be026cc296d 106 PRINTS PR00355 Adrenodoxin signature 40 50 2.3E-7 T 13-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 Astex_0212 3575c4ef07cc3ae80f237be026cc296d 106 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 7 91 3.4E-16 T 13-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 Astex_0212 3575c4ef07cc3ae80f237be026cc296d 106 Gene3D G3DSA:3.10.20.30 1 106 1.1E-37 T 13-10-2018 IPR012675 Beta-grasp domain superfamily Astex_3857 e177c857c9b4d7b3a540230607c4641c 340 Gene3D G3DSA:2.40.30.170 97 110 2.5E-9 T 13-10-2018 Astex_3857 e177c857c9b4d7b3a540230607c4641c 340 SUPERFAMILY SSF51230 115 187 6.28E-10 T 13-10-2018 IPR011053 Single hybrid motif Astex_3857 e177c857c9b4d7b3a540230607c4641c 340 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 149 253 3.6E-14 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain Astex_3857 e177c857c9b4d7b3a540230607c4641c 340 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 146 330 2.8E-29 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 Astex_3857 e177c857c9b4d7b3a540230607c4641c 340 Gene3D G3DSA:2.40.420.20 87 96 2.5E-9 T 13-10-2018 Astex_3857 e177c857c9b4d7b3a540230607c4641c 340 Gene3D G3DSA:2.40.50.100 149 183 2.9E-13 T 13-10-2018 Astex_3857 e177c857c9b4d7b3a540230607c4641c 340 Gene3D G3DSA:2.40.50.100 111 144 2.5E-9 T 13-10-2018 Astex_3857 e177c857c9b4d7b3a540230607c4641c 340 Gene3D G3DSA:2.40.30.170 184 254 2.9E-13 T 13-10-2018 Astex_3857 e177c857c9b4d7b3a540230607c4641c 340 Gene3D G3DSA:2.40.420.20 259 340 8.2E-16 T 13-10-2018 Astex_0414 427943afde9580adff019458d2c1a700 348 SUPERFAMILY SSF51735 17 292 2.2E-55 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_0414 427943afde9580adff019458d2c1a700 348 Pfam PF02719 Polysaccharide biosynthesis protein 20 299 2.1E-100 T 13-10-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain Astex_0414 427943afde9580adff019458d2c1a700 348 TIGRFAM TIGR03589 PseB: UDP-N-acetylglucosamine 4,6-dehydratase (inverting) 16 342 8.4E-153 T 13-10-2018 IPR020025 UDP-N-acetylglucosamine 4,6-dehydratase (inverting) KEGG: 00520+4.2.1.115|MetaCyc: PWY-6143|MetaCyc: PWY-7330|MetaCyc: PWY-7331|MetaCyc: PWY-7332|MetaCyc: PWY-7719 Astex_0414 427943afde9580adff019458d2c1a700 348 Gene3D G3DSA:3.40.50.720 18 326 4.2E-122 T 13-10-2018 Astex_0414 427943afde9580adff019458d2c1a700 348 Gene3D G3DSA:3.90.25.30 187 328 4.2E-122 T 13-10-2018 Astex_2160 4f8ceb93749615b2a2b62ab528091b93 105 Gene3D G3DSA:3.30.70.100 1 98 7.5E-40 T 13-10-2018 Astex_2160 4f8ceb93749615b2a2b62ab528091b93 105 Hamap MF_01663 L-rhamnose mutarotase [rhaM]. 2 105 31.791 T 13-10-2018 IPR013448 L-rhamnose mutarotase GO:0005737|GO:0016857|GO:0019299 Astex_2160 4f8ceb93749615b2a2b62ab528091b93 105 SUPERFAMILY SSF54909 4 104 5.54E-38 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel Astex_2160 4f8ceb93749615b2a2b62ab528091b93 105 Pfam PF05336 L-rhamnose mutarotase 6 104 1.3E-28 T 13-10-2018 IPR008000 Rhamnose/fucose mutarotase GO:0005737|GO:0016857 Astex_2160 4f8ceb93749615b2a2b62ab528091b93 105 TIGRFAM TIGR02625 YiiL_rotase: L-rhamnose mutarotase 6 104 6.1E-35 T 13-10-2018 IPR013448 L-rhamnose mutarotase GO:0005737|GO:0016857|GO:0019299 Astex_2849 83c476b3aec15ff4b84bd4f40794af76 407 SUPERFAMILY SSF51735 2 150 5.15E-39 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_2849 83c476b3aec15ff4b84bd4f40794af76 407 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4 132 5.2E-36 T 13-10-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 Astex_2849 83c476b3aec15ff4b84bd4f40794af76 407 SUPERFAMILY SSF69055 292 384 3.53E-25 T 13-10-2018 IPR036169 DXP reductoisomerase, C-terminal domain superfamily KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 Astex_2849 83c476b3aec15ff4b84bd4f40794af76 407 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1 363 4.2E-133 T 13-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 Astex_2849 83c476b3aec15ff4b84bd4f40794af76 407 Pfam PF13288 DXP reductoisomerase C-terminal domain 261 384 2.7E-39 T 13-10-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 Astex_2849 83c476b3aec15ff4b84bd4f40794af76 407 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 146 229 1.7E-38 T 13-10-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 Astex_2849 83c476b3aec15ff4b84bd4f40794af76 407 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 4 389 44.376 T 13-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 Astex_2849 83c476b3aec15ff4b84bd4f40794af76 407 Gene3D G3DSA:3.40.50.720 1 150 5.2E-44 T 13-10-2018 Astex_2849 83c476b3aec15ff4b84bd4f40794af76 407 Gene3D G3DSA:1.10.1740.10 302 390 1.0E-23 T 13-10-2018 Astex_2849 83c476b3aec15ff4b84bd4f40794af76 407 PIRSF PIRSF006205 1 393 1.3E-143 T 13-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 Astex_2849 83c476b3aec15ff4b84bd4f40794af76 407 SUPERFAMILY SSF55347 126 264 3.17E-56 T 13-10-2018 Astex_2998 8078e54a3a1b3def1d5eb967b50b4493 266 SUPERFAMILY SSF52833 103 258 1.4E-30 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Astex_2998 8078e54a3a1b3def1d5eb967b50b4493 266 Pfam PF13462 Thioredoxin 104 258 1.5E-20 T 13-10-2018 IPR012336 Thioredoxin-like fold Astex_2998 8078e54a3a1b3def1d5eb967b50b4493 266 Gene3D G3DSA:3.40.30.10 74 265 5.3E-35 T 13-10-2018 Astex_1038 29ec99f2ef1bbd1297a26ef170534826 676 Gene3D G3DSA:2.170.130.10 40 166 5.5E-13 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_1038 29ec99f2ef1bbd1297a26ef170534826 676 Pfam PF00593 TonB dependent receptor 253 674 3.3E-33 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_1038 29ec99f2ef1bbd1297a26ef170534826 676 SUPERFAMILY SSF56935 39 676 2.65E-80 T 13-10-2018 Astex_1038 29ec99f2ef1bbd1297a26ef170534826 676 Pfam PF07715 TonB-dependent Receptor Plug Domain 57 161 1.9E-14 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_1038 29ec99f2ef1bbd1297a26ef170534826 676 Gene3D G3DSA:2.40.170.20 177 676 6.8E-61 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_2729 7ba1e0a12015217b6cf7189d70e956af 693 Pfam PF01120 Alpha-L-fucosidase 41 338 1.7E-36 T 13-10-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 Astex_2729 7ba1e0a12015217b6cf7189d70e956af 693 SMART SM00812 31 379 1.7E-12 T 13-10-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 Astex_2729 7ba1e0a12015217b6cf7189d70e956af 693 SUPERFAMILY SSF49785 558 691 9.22E-11 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_2729 7ba1e0a12015217b6cf7189d70e956af 693 Pfam PF00754 F5/8 type C domain 358 463 2.2E-11 T 13-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain Astex_2729 7ba1e0a12015217b6cf7189d70e956af 693 Pfam PF00754 F5/8 type C domain 564 675 1.2E-6 T 13-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain Astex_2729 7ba1e0a12015217b6cf7189d70e956af 693 SUPERFAMILY SSF51445 29 345 1.31E-82 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_2729 7ba1e0a12015217b6cf7189d70e956af 693 SUPERFAMILY SSF49785 349 464 9.22E-11 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_2729 7ba1e0a12015217b6cf7189d70e956af 693 Gene3D G3DSA:3.20.20.80 30 352 3.8E-118 T 13-10-2018 Astex_2729 7ba1e0a12015217b6cf7189d70e956af 693 Pfam PF13287 Fn3 associated 494 541 7.8E-10 T 13-10-2018 IPR026876 Fn3 associated repeat Astex_2729 7ba1e0a12015217b6cf7189d70e956af 693 Gene3D G3DSA:2.60.120.260 353 476 2.3E-23 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_2729 7ba1e0a12015217b6cf7189d70e956af 693 Gene3D G3DSA:2.60.120.260 554 693 1.5E-13 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_2366 e03a31db75f5b765bf2ddd36e31a5e4d 213 Gene3D G3DSA:3.40.50.300 1 212 5.0E-62 T 13-10-2018 Astex_2366 e03a31db75f5b765bf2ddd36e31a5e4d 213 Pfam PF02224 Cytidylate kinase 7 206 1.3E-54 T 13-10-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 Astex_2366 e03a31db75f5b765bf2ddd36e31a5e4d 213 Hamap MF_00238 Cytidylate kinase [cmk]. 5 210 29.101 T 13-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 Astex_2366 e03a31db75f5b765bf2ddd36e31a5e4d 213 TIGRFAM TIGR00017 cmk: cytidylate kinase 5 201 4.4E-50 T 13-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 Astex_2366 e03a31db75f5b765bf2ddd36e31a5e4d 213 SUPERFAMILY SSF52540 1 206 2.03E-33 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0495 8c9e7a149a96c080acb7cb142c35dd0a 189 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 8 184 1.5E-52 T 13-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 Astex_0495 8c9e7a149a96c080acb7cb142c35dd0a 189 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 24 184 2.0E-44 T 13-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 Astex_0495 8c9e7a149a96c080acb7cb142c35dd0a 189 Pfam PF01923 Cobalamin adenosyltransferase 7 173 2.4E-57 T 13-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 Astex_0495 8c9e7a149a96c080acb7cb142c35dd0a 189 Gene3D G3DSA:1.20.1200.10 28 189 1.1E-53 T 13-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 Astex_0495 8c9e7a149a96c080acb7cb142c35dd0a 189 SUPERFAMILY SSF89028 6 185 1.79E-57 T 13-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 Astex_2276 0af3a55fc8ed36690d67c0d2f3c81da5 251 Pfam PF00005 ABC transporter 50 181 1.9E-20 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_2276 0af3a55fc8ed36690d67c0d2f3c81da5 251 SUPERFAMILY SSF52540 47 240 5.98E-43 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2276 0af3a55fc8ed36690d67c0d2f3c81da5 251 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Astex_2276 0af3a55fc8ed36690d67c0d2f3c81da5 251 SMART SM00382 59 230 3.0E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_2276 0af3a55fc8ed36690d67c0d2f3c81da5 251 Gene3D G3DSA:3.40.50.300 40 246 6.5E-39 T 13-10-2018 Astex_1478 7c82fbc723fb62f8ce6d36671a8b7569 371 Pfam PF14350 Beta protein 4 341 2.2E-70 T 13-10-2018 IPR025683 Protein beta Astex_2389 58c09952c568d3ba75fe9476ef517294 784 Gene3D G3DSA:2.40.170.20 168 784 7.6E-56 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_2389 58c09952c568d3ba75fe9476ef517294 784 Gene3D G3DSA:2.170.130.10 30 159 2.0E-13 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_2389 58c09952c568d3ba75fe9476ef517294 784 Pfam PF00593 TonB dependent receptor 246 772 2.4E-35 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_2389 58c09952c568d3ba75fe9476ef517294 784 Pfam PF07715 TonB-dependent Receptor Plug Domain 48 154 5.5E-14 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_2389 58c09952c568d3ba75fe9476ef517294 784 SUPERFAMILY SSF56935 20 784 1.5E-87 T 13-10-2018 Astex_3828 d127592c471d66e4e714403b77b2d5e1 399 Pfam PF00872 Transposase, Mutator family 4 371 7.5E-125 T 13-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 Astex_2824 083b215bced2ed750806bd1fdee8c687 622 SUPERFAMILY SSF64182 90 500 5.49E-110 T 13-10-2018 IPR038763 DHH phosphoesterase superfamily Astex_2824 083b215bced2ed750806bd1fdee8c687 622 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 62 616 1.5E-160 T 13-10-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 Astex_2824 083b215bced2ed750806bd1fdee8c687 622 Pfam PF01368 DHH family 114 224 2.1E-8 T 13-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 Astex_2824 083b215bced2ed750806bd1fdee8c687 622 Gene3D G3DSA:3.10.310.30 369 496 3.1E-29 T 13-10-2018 Astex_2824 083b215bced2ed750806bd1fdee8c687 622 Gene3D G3DSA:3.90.1640.30 92 367 7.3E-81 T 13-10-2018 Astex_2824 083b215bced2ed750806bd1fdee8c687 622 Pfam PF02272 DHHA1 domain 363 492 6.6E-23 T 13-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 Astex_2823 187d02ed800203a33f00f77ca258ae0f 322 PIRSF PIRSF004532 5 322 5.4E-132 T 13-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 Astex_2823 187d02ed800203a33f00f77ca258ae0f 322 Gene3D G3DSA:3.40.190.90 124 288 5.9E-124 T 13-10-2018 Astex_2823 187d02ed800203a33f00f77ca258ae0f 322 SUPERFAMILY SSF56655 7 315 1.65E-101 T 13-10-2018 Astex_2823 187d02ed800203a33f00f77ca258ae0f 322 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 7 314 4.1E-133 T 13-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 Astex_2823 187d02ed800203a33f00f77ca258ae0f 322 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 7 315 5.8E-103 T 13-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 Astex_2823 187d02ed800203a33f00f77ca258ae0f 322 Gene3D G3DSA:3.30.540.10 8 314 5.9E-124 T 13-10-2018 Astex_0015 0417582f3dd18e5651799d5615b45c3d 319 Pfam PF01435 Peptidase family M48 98 301 4.9E-40 T 13-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 Astex_0015 0417582f3dd18e5651799d5615b45c3d 319 Gene3D G3DSA:3.30.2010.10 86 173 6.6E-31 T 13-10-2018 Astex_0015 0417582f3dd18e5651799d5615b45c3d 319 Hamap MF_00188 Protease HtpX [htpX]. 24 302 27.624 T 13-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 Astex_2393 28a96607a27cb655cdab40d690e8adae 177 Gene3D G3DSA:1.10.10.10 97 173 3.0E-18 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_2393 28a96607a27cb655cdab40d690e8adae 177 Pfam PF08281 Sigma-70, region 4 118 169 5.9E-17 T 13-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Astex_2393 28a96607a27cb655cdab40d690e8adae 177 SUPERFAMILY SSF88659 97 170 2.8E-18 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Astex_2393 28a96607a27cb655cdab40d690e8adae 177 Pfam PF04542 Sigma-70 region 2 19 82 4.4E-9 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 Astex_2393 28a96607a27cb655cdab40d690e8adae 177 SUPERFAMILY SSF88946 14 90 2.59E-12 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 Astex_2393 28a96607a27cb655cdab40d690e8adae 177 Gene3D G3DSA:1.10.1740.10 6 86 5.2E-9 T 13-10-2018 Astex_2393 28a96607a27cb655cdab40d690e8adae 177 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 16 170 1.5E-26 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 Astex_2909 6ede017e75a31b95296240568da11fa3 167 SUPERFAMILY SSF142433 3 163 1.06E-52 T 13-10-2018 IPR036653 CinA-like, C-terminal Astex_2909 6ede017e75a31b95296240568da11fa3 167 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 14 158 3.2E-42 T 13-10-2018 IPR008136 CinA, C-terminal Astex_2909 6ede017e75a31b95296240568da11fa3 167 Pfam PF02464 Competence-damaged protein 5 162 7.9E-55 T 13-10-2018 IPR008136 CinA, C-terminal Astex_2909 6ede017e75a31b95296240568da11fa3 167 Gene3D G3DSA:3.90.950.20 1 167 2.1E-57 T 13-10-2018 IPR036653 CinA-like, C-terminal Astex_2603 7a227474db7c1577f1a8734df0143606 290 SUPERFAMILY SSF51182 5 287 8.16E-78 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily Astex_2603 7a227474db7c1577f1a8734df0143606 290 Gene3D G3DSA:2.60.120.10 18 270 4.3E-70 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Astex_2603 7a227474db7c1577f1a8734df0143606 290 PIRSF PIRSF006232 1 283 4.7E-87 T 13-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 Astex_2603 7a227474db7c1577f1a8734df0143606 290 Gene3D G3DSA:2.60.120.10 146 245 4.3E-70 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Astex_2603 7a227474db7c1577f1a8734df0143606 290 Pfam PF02678 Pirin 19 123 2.2E-31 T 13-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 Astex_2603 7a227474db7c1577f1a8734df0143606 290 Pfam PF05726 Pirin C-terminal cupin domain 177 274 4.1E-24 T 13-10-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 Astex_1288 d702735fb232c983bfc21d7f83533643 249 Gene3D G3DSA:3.30.1150.10 123 248 6.0E-26 T 13-10-2018 Astex_1288 d702735fb232c983bfc21d7f83533643 249 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 168 246 2.1E-25 T 13-10-2018 IPR037682 TonB, C-terminal GO:0055085 Astex_1288 d702735fb232c983bfc21d7f83533643 249 PRINTS PR01374 Gram-negative bacterial tonB protein signature 101 111 3.4E-7 T 13-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 Astex_1288 d702735fb232c983bfc21d7f83533643 249 PRINTS PR01374 Gram-negative bacterial tonB protein signature 185 203 3.4E-7 T 13-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 Astex_1288 d702735fb232c983bfc21d7f83533643 249 PRINTS PR01374 Gram-negative bacterial tonB protein signature 164 185 3.4E-7 T 13-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 Astex_1288 d702735fb232c983bfc21d7f83533643 249 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 170 246 1.7E-22 T 13-10-2018 IPR006260 TonB/TolA, C-terminal Astex_1288 d702735fb232c983bfc21d7f83533643 249 SUPERFAMILY SSF74653 166 244 2.35E-24 T 13-10-2018 Astex_1631 f6237b813052c36a6adc8fa0aab00267 660 SUPERFAMILY SSF56519 58 256 2.35E-44 T 13-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 Astex_1631 f6237b813052c36a6adc8fa0aab00267 660 Gene3D G3DSA:3.40.710.10 253 619 2.4E-92 T 13-10-2018 Astex_1631 f6237b813052c36a6adc8fa0aab00267 660 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 20 614 9.9E-196 T 13-10-2018 IPR017790 Penicillin-binding protein 2 GO:0008658|GO:0009002|GO:0009252|GO:0016020 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 Astex_1631 f6237b813052c36a6adc8fa0aab00267 660 Gene3D G3DSA:3.90.1310.30 59 252 9.7E-39 T 13-10-2018 Astex_1631 f6237b813052c36a6adc8fa0aab00267 660 SUPERFAMILY SSF56601 257 614 1.4E-89 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like Astex_1631 f6237b813052c36a6adc8fa0aab00267 660 Pfam PF03717 Penicillin-binding Protein dimerisation domain 66 239 4.9E-43 T 13-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 Astex_1631 f6237b813052c36a6adc8fa0aab00267 660 Pfam PF00905 Penicillin binding protein transpeptidase domain 274 611 2.1E-65 T 13-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 Astex_3563 16414b083ce985bfb459b8432a0e0f40 277 PRINTS PR00412 Epoxide hydrolase signature 218 234 9.0E-5 T 13-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 Astex_3563 16414b083ce985bfb459b8432a0e0f40 277 PRINTS PR00412 Epoxide hydrolase signature 50 65 9.0E-5 T 13-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 Astex_3563 16414b083ce985bfb459b8432a0e0f40 277 PRINTS PR00412 Epoxide hydrolase signature 30 48 9.0E-5 T 13-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 Astex_3563 16414b083ce985bfb459b8432a0e0f40 277 Gene3D G3DSA:3.40.50.1820 1 276 1.2E-79 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_3563 16414b083ce985bfb459b8432a0e0f40 277 Pfam PF12146 Serine aminopeptidase, S33 25 260 1.1E-23 T 13-10-2018 IPR022742 Serine aminopeptidase, S33 Astex_3563 16414b083ce985bfb459b8432a0e0f40 277 SUPERFAMILY SSF53474 4 276 6.16E-62 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_3563 16414b083ce985bfb459b8432a0e0f40 277 PRINTS PR00111 Alpha/beta hydrolase fold signature 50 65 3.5E-10 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Astex_3563 16414b083ce985bfb459b8432a0e0f40 277 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 107 3.5E-10 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Astex_3563 16414b083ce985bfb459b8432a0e0f40 277 PRINTS PR00111 Alpha/beta hydrolase fold signature 220 234 3.5E-10 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Astex_2295 db8ab05ef5a6981e2d6290970f921226 339 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 53 66 - T 13-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 Astex_2295 db8ab05ef5a6981e2d6290970f921226 339 Gene3D G3DSA:3.40.50.1100 24 318 4.3E-96 T 13-10-2018 Astex_2295 db8ab05ef5a6981e2d6290970f921226 339 SUPERFAMILY SSF53686 16 322 1.83E-79 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme Astex_2295 db8ab05ef5a6981e2d6290970f921226 339 Gene3D G3DSA:3.40.50.1100 61 156 4.3E-96 T 13-10-2018 Astex_2295 db8ab05ef5a6981e2d6290970f921226 339 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 26 314 1.5E-67 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme Astex_1899 b5993ae0e448bff10b5c1515f783e320 433 TIGRFAM TIGR00885 fucP: L-fucose:H+ symporter permease 15 419 2.8E-129 T 13-10-2018 IPR005275 L-fucose permease FucP GO:0015150|GO:0015756 Astex_1899 b5993ae0e448bff10b5c1515f783e320 433 SUPERFAMILY SSF103473 10 422 6.67E-43 T 13-10-2018 IPR036259 MFS transporter superfamily Astex_1899 b5993ae0e448bff10b5c1515f783e320 433 Gene3D G3DSA:1.20.1250.20 235 423 4.3E-52 T 13-10-2018 Astex_1899 b5993ae0e448bff10b5c1515f783e320 433 Gene3D G3DSA:1.20.1250.20 12 230 9.8E-60 T 13-10-2018 Astex_1899 b5993ae0e448bff10b5c1515f783e320 433 Pfam PF07690 Major Facilitator Superfamily 24 362 2.7E-23 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Astex_3264 d12ab1da49a5dbe3c989cf172ebfa84d 214 Pfam PF02698 DUF218 domain 39 178 1.7E-11 T 13-10-2018 IPR003848 Domain of unknown function DUF218 Astex_2394 457c2af4e20e9ef3c1433e795c30efd5 314 Gene3D G3DSA:2.60.120.1440 101 236 2.0E-9 T 13-10-2018 Astex_2394 457c2af4e20e9ef3c1433e795c30efd5 314 PIRSF PIRSF018266 1 314 2.3E-58 T 13-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component Astex_2394 457c2af4e20e9ef3c1433e795c30efd5 314 Gene3D G3DSA:3.55.50.30 238 309 4.5E-6 T 13-10-2018 Astex_2394 457c2af4e20e9ef3c1433e795c30efd5 314 Pfam PF16220 Domain of unknown function (DUF4880) 6 46 2.4E-13 T 13-10-2018 IPR032623 FecR, N-terminal Astex_2394 457c2af4e20e9ef3c1433e795c30efd5 314 Pfam PF16344 Domain of unknown function (DUF4974) 226 300 5.7E-8 T 13-10-2018 IPR032508 Protein FecR, C-terminal Astex_2394 457c2af4e20e9ef3c1433e795c30efd5 314 Pfam PF04773 FecR protein 110 199 2.7E-13 T 13-10-2018 IPR006860 FecR protein Astex_0115 e8196aed8ba715470bb8cd40e7b80257 511 Gene3D G3DSA:3.40.1080.10 28 217 1.6E-13 T 13-10-2018 Astex_0115 e8196aed8ba715470bb8cd40e7b80257 511 Gene3D G3DSA:3.30.750.70 242 326 8.5E-6 T 13-10-2018 Astex_0115 e8196aed8ba715470bb8cd40e7b80257 511 TIGRFAM TIGR03458 YgfH_subfam: succinate CoA transferase 27 509 4.5E-225 T 13-10-2018 IPR017821 Succinate CoA transferase GO:0006084|GO:0016740 Astex_0115 e8196aed8ba715470bb8cd40e7b80257 511 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 334 477 5.8E-41 T 13-10-2018 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain Astex_0115 e8196aed8ba715470bb8cd40e7b80257 511 Gene3D G3DSA:3.40.1080.20 350 490 2.4E-38 T 13-10-2018 IPR038460 Acetyl-CoA hydrolase/transferase, C-terminal domain superfamily Astex_0115 e8196aed8ba715470bb8cd40e7b80257 511 SUPERFAMILY SSF100950 241 510 1.02E-78 T 13-10-2018 IPR037171 NagB/RpiA transferase-like Astex_0115 e8196aed8ba715470bb8cd40e7b80257 511 SUPERFAMILY SSF100950 18 236 1.64E-69 T 13-10-2018 IPR037171 NagB/RpiA transferase-like Astex_0115 e8196aed8ba715470bb8cd40e7b80257 511 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 28 229 7.7E-30 T 13-10-2018 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 Astex_3395 ee0bfef894d5c4d861b3c9ee7ad343de 219 SUPERFAMILY SSF48008 76 208 1.44E-24 T 13-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal Astex_3395 ee0bfef894d5c4d861b3c9ee7ad343de 219 SMART SM00895 80 204 3.4E-14 T 13-10-2018 IPR011711 GntR, C-terminal Astex_3395 ee0bfef894d5c4d861b3c9ee7ad343de 219 Gene3D G3DSA:1.10.10.10 4 71 2.5E-18 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_3395 ee0bfef894d5c4d861b3c9ee7ad343de 219 Pfam PF07729 FCD domain 80 203 5.6E-23 T 13-10-2018 IPR011711 GntR, C-terminal Astex_3395 ee0bfef894d5c4d861b3c9ee7ad343de 219 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 70 6.1E-16 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Astex_3395 ee0bfef894d5c4d861b3c9ee7ad343de 219 Gene3D G3DSA:1.20.120.530 74 218 6.4E-26 T 13-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal Astex_3395 ee0bfef894d5c4d861b3c9ee7ad343de 219 SUPERFAMILY SSF46785 7 96 2.17E-17 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_3395 ee0bfef894d5c4d861b3c9ee7ad343de 219 SMART SM00345 12 70 1.8E-13 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Astex_3520 6c668a74564e90d5cfe77e340e65504e 271 PRINTS PR00377 Inositol monophosphatase superfamily signature 137 160 2.2E-16 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Astex_3520 6c668a74564e90d5cfe77e340e65504e 271 PRINTS PR00377 Inositol monophosphatase superfamily signature 208 232 2.2E-16 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Astex_3520 6c668a74564e90d5cfe77e340e65504e 271 PRINTS PR00377 Inositol monophosphatase superfamily signature 44 64 2.2E-16 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Astex_3520 6c668a74564e90d5cfe77e340e65504e 271 PRINTS PR00377 Inositol monophosphatase superfamily signature 88 104 2.2E-16 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Astex_3520 6c668a74564e90d5cfe77e340e65504e 271 SUPERFAMILY SSF56655 9 260 1.44E-61 T 13-10-2018 Astex_3520 6c668a74564e90d5cfe77e340e65504e 271 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 88 101 - T 13-10-2018 IPR020583 Inositol monophosphatase, metal-binding site Astex_3520 6c668a74564e90d5cfe77e340e65504e 271 Pfam PF00459 Inositol monophosphatase family 17 253 1.6E-39 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 Astex_3520 6c668a74564e90d5cfe77e340e65504e 271 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 211 225 - T 13-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 Astex_3520 6c668a74564e90d5cfe77e340e65504e 271 Gene3D G3DSA:3.30.540.10 2 146 4.8E-36 T 13-10-2018 Astex_3520 6c668a74564e90d5cfe77e340e65504e 271 Gene3D G3DSA:3.40.190.80 178 265 5.7E-17 T 13-10-2018 Astex_3538 d52447e04e9fe9a9d86247e0e51bd03e 564 Gene3D G3DSA:2.160.20.10 71 158 8.1E-15 T 13-10-2018 IPR012334 Pectin lyase fold Astex_3538 d52447e04e9fe9a9d86247e0e51bd03e 564 SUPERFAMILY SSF51126 66 442 1.65E-19 T 13-10-2018 IPR011050 Pectin lyase fold/virulence factor Astex_3538 d52447e04e9fe9a9d86247e0e51bd03e 564 Pfam PF12708 Pectate lyase superfamily protein 72 135 6.9E-10 T 13-10-2018 IPR024535 Pectate lyase superfamily protein Astex_0683 b8cd59f1efa2aca7843a4c6876e867e7 336 SUPERFAMILY SSF55961 193 335 1.69E-27 T 13-10-2018 Astex_0683 b8cd59f1efa2aca7843a4c6876e867e7 336 SUPERFAMILY SSF55961 13 186 3.18E-35 T 13-10-2018 Astex_0683 b8cd59f1efa2aca7843a4c6876e867e7 336 Gene3D G3DSA:3.30.530.20 14 193 6.3E-41 T 13-10-2018 IPR023393 START-like domain superfamily Astex_0683 b8cd59f1efa2aca7843a4c6876e867e7 336 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 32 164 7.2E-15 T 13-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like Astex_0683 b8cd59f1efa2aca7843a4c6876e867e7 336 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 204 335 1.1E-19 T 13-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like Astex_0683 b8cd59f1efa2aca7843a4c6876e867e7 336 Gene3D G3DSA:3.30.530.20 194 336 1.1E-28 T 13-10-2018 IPR023393 START-like domain superfamily Astex_0457 17e219d08ee2b48fb31c3b49c2662f71 429 PIRSF PIRSF001362 1 426 2.6E-224 T 13-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 Astex_0457 17e219d08ee2b48fb31c3b49c2662f71 429 Pfam PF00463 Isocitrate lyase family 245 422 6.0E-42 T 13-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 Astex_0457 17e219d08ee2b48fb31c3b49c2662f71 429 Pfam PF00463 Isocitrate lyase family 15 241 1.4E-51 T 13-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 Astex_0457 17e219d08ee2b48fb31c3b49c2662f71 429 SUPERFAMILY SSF51621 10 423 3.32E-145 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 Astex_0457 17e219d08ee2b48fb31c3b49c2662f71 429 Gene3D G3DSA:3.20.20.60 1 406 2.4E-169 T 13-10-2018 Astex_0457 17e219d08ee2b48fb31c3b49c2662f71 429 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 14 241 1.0E-92 T 13-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 Astex_0457 17e219d08ee2b48fb31c3b49c2662f71 429 ProSitePatterns PS00161 Isocitrate lyase signature. 181 186 - T 13-10-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824 Astex_2990 09230f7efc35ae58981208f5c213e026 1357 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 13 1355 12.385 T 13-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Astex_2990 09230f7efc35ae58981208f5c213e026 1357 Gene3D G3DSA:2.40.50.100 720 797 5.4E-31 T 13-10-2018 Astex_2990 09230f7efc35ae58981208f5c213e026 1357 Pfam PF00562 RNA polymerase Rpb2, domain 6 724 1277 6.3E-165 T 13-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Astex_2990 09230f7efc35ae58981208f5c213e026 1357 Gene3D G3DSA:3.90.1100.10 18 177 4.5E-59 T 13-10-2018 Astex_2990 09230f7efc35ae58981208f5c213e026 1357 Gene3D G3DSA:3.90.1100.10 651 719 1.6E-20 T 13-10-2018 Astex_2990 09230f7efc35ae58981208f5c213e026 1357 Gene3D G3DSA:2.40.270.10 1053 1255 1.0E-77 T 13-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Astex_2990 09230f7efc35ae58981208f5c213e026 1357 Gene3D G3DSA:3.90.1800.10 1265 1320 9.1E-11 T 13-10-2018 Astex_2990 09230f7efc35ae58981208f5c213e026 1357 Gene3D G3DSA:3.90.1100.10 450 631 4.2E-71 T 13-10-2018 Astex_2990 09230f7efc35ae58981208f5c213e026 1357 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 8 1352 0.0 T 13-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Astex_2990 09230f7efc35ae58981208f5c213e026 1357 Gene3D G3DSA:3.90.1110.10 316 449 1.7E-33 T 13-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Astex_2990 09230f7efc35ae58981208f5c213e026 1357 Pfam PF04560 RNA polymerase Rpb2, domain 7 1279 1353 1.6E-26 T 13-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Astex_2990 09230f7efc35ae58981208f5c213e026 1357 Pfam PF04561 RNA polymerase Rpb2, domain 2 354 461 1.6E-18 T 13-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Astex_2990 09230f7efc35ae58981208f5c213e026 1357 Pfam PF04561 RNA polymerase Rpb2, domain 2 178 228 6.4E-6 T 13-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Astex_2990 09230f7efc35ae58981208f5c213e026 1357 Pfam PF04565 RNA polymerase Rpb2, domain 3 520 588 4.3E-32 T 13-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Astex_2990 09230f7efc35ae58981208f5c213e026 1357 Pfam PF04563 RNA polymerase beta subunit 27 504 1.2E-33 T 13-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Astex_2990 09230f7efc35ae58981208f5c213e026 1357 Gene3D G3DSA:2.40.50.150 837 959 2.1E-45 T 13-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Astex_2990 09230f7efc35ae58981208f5c213e026 1357 Pfam PF10385 RNA polymerase beta subunit external 1 domain 598 662 3.1E-18 T 13-10-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Astex_2990 09230f7efc35ae58981208f5c213e026 1357 ProSitePatterns PS01166 RNA polymerases beta chain signature. 1080 1092 - T 13-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Astex_2990 09230f7efc35ae58981208f5c213e026 1357 SUPERFAMILY SSF64484 11 1354 0.0 T 13-10-2018 Astex_2990 09230f7efc35ae58981208f5c213e026 1357 Gene3D G3DSA:2.40.270.10 798 836 5.3E-7 T 13-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 Astex_2526 5fb62da79ff7031902d0c2c3eb7f082a 302 SUPERFAMILY SSF88713 3 299 1.75E-78 T 13-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 Astex_2526 5fb62da79ff7031902d0c2c3eb7f082a 302 Gene3D G3DSA:3.20.20.370 1 301 2.7E-89 T 13-10-2018 Astex_2526 5fb62da79ff7031902d0c2c3eb7f082a 302 TIGRFAM TIGR03212 uraD_N-term-dom: putative urate catabolism protein 3 299 4.7E-153 T 13-10-2018 IPR017625 PuuE allantoinase/chitin deacetylase 1 Astex_2526 5fb62da79ff7031902d0c2c3eb7f082a 302 Pfam PF01522 Polysaccharide deacetylase 73 180 1.1E-9 T 13-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 Astex_3200 e1ae47b9f0b5c4e1375146769f6f25ba 68 Pfam PF09834 Predicted membrane protein (DUF2061) 4 55 1.6E-19 T 13-10-2018 IPR018638 Domain of unknown function DUF2061, membrane Astex_2985 1c627219531657a2152a75612a543f85 229 SUPERFAMILY SSF56281 12 213 7.72E-54 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Astex_2985 1c627219531657a2152a75612a543f85 229 Pfam PF00753 Metallo-beta-lactamase superfamily 15 183 8.2E-28 T 13-10-2018 IPR001279 Metallo-beta-lactamase Astex_2985 1c627219531657a2152a75612a543f85 229 SMART SM00849 18 197 3.0E-36 T 13-10-2018 IPR001279 Metallo-beta-lactamase Astex_2985 1c627219531657a2152a75612a543f85 229 Gene3D G3DSA:3.60.15.10 8 215 1.6E-71 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Astex_1593 54ea237427139fb2fa64d37342c3ae1d 127 Pfam PF01381 Helix-turn-helix 13 67 7.4E-12 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Astex_1593 54ea237427139fb2fa64d37342c3ae1d 127 SUPERFAMILY SSF47413 2 78 6.86E-25 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Astex_1593 54ea237427139fb2fa64d37342c3ae1d 127 Gene3D G3DSA:1.10.260.40 2 74 1.4E-17 T 13-10-2018 Astex_1593 54ea237427139fb2fa64d37342c3ae1d 127 SMART SM00530 12 67 9.9E-14 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Astex_3035 769eb88cf0cfceb02eb4f320c76c12d8 267 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 22 215 2.0E-40 T 13-10-2018 IPR001303 Class II aldolase/adducin N-terminal Astex_3035 769eb88cf0cfceb02eb4f320c76c12d8 267 SMART SM01007 21 215 2.1E-54 T 13-10-2018 IPR001303 Class II aldolase/adducin N-terminal Astex_3035 769eb88cf0cfceb02eb4f320c76c12d8 267 Gene3D G3DSA:3.40.225.10 10 266 3.1E-69 T 13-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily Astex_3035 769eb88cf0cfceb02eb4f320c76c12d8 267 SUPERFAMILY SSF53639 12 229 1.45E-56 T 13-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily Astex_2059 914c50590ecf5b7ba24617730cd16444 353 Pfam PF14696 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal 6 138 7.6E-39 T 13-10-2018 Astex_2059 914c50590ecf5b7ba24617730cd16444 353 PIRSF PIRSF009283 2 352 4.2E-89 T 13-10-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 Astex_2059 914c50590ecf5b7ba24617730cd16444 353 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 161 271 3.2E-13 T 13-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Astex_2059 914c50590ecf5b7ba24617730cd16444 353 Gene3D G3DSA:3.10.180.10 155 352 1.8E-55 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Astex_2059 914c50590ecf5b7ba24617730cd16444 353 Gene3D G3DSA:3.10.180.10 3 144 3.3E-33 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Astex_2059 914c50590ecf5b7ba24617730cd16444 353 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 13 350 2.8E-86 T 13-10-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 Astex_2059 914c50590ecf5b7ba24617730cd16444 353 SUPERFAMILY SSF54593 6 337 1.68E-62 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Astex_3460 d7381ff50ae8e5266e4c2ede13725811 162 SUPERFAMILY SSF53927 2 152 1.47E-50 T 13-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 Astex_3460 d7381ff50ae8e5266e4c2ede13725811 162 Gene3D G3DSA:3.40.140.10 1 160 2.2E-51 T 13-10-2018 Astex_3460 d7381ff50ae8e5266e4c2ede13725811 162 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 54 91 - T 13-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 Astex_3460 d7381ff50ae8e5266e4c2ede13725811 162 Pfam PF14437 MafB19-like deaminase 2 150 8.5E-26 T 13-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 Astex_3460 d7381ff50ae8e5266e4c2ede13725811 162 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 7 150 46.085 T 13-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 Astex_3431 0dcdd17c9a3d787ffd6dc4455a939e7a 235 SUPERFAMILY SSF46689 17 93 2.57E-17 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Astex_3431 0dcdd17c9a3d787ffd6dc4455a939e7a 235 Gene3D G3DSA:1.10.357.10 28 232 2.4E-61 T 13-10-2018 Astex_3431 0dcdd17c9a3d787ffd6dc4455a939e7a 235 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 51 74 6.7E-7 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Astex_3431 0dcdd17c9a3d787ffd6dc4455a939e7a 235 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 43 6.7E-7 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Astex_3431 0dcdd17c9a3d787ffd6dc4455a939e7a 235 Pfam PF00440 Bacterial regulatory proteins, tetR family 31 76 3.3E-14 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Astex_3431 0dcdd17c9a3d787ffd6dc4455a939e7a 235 SUPERFAMILY SSF48498 101 225 4.27E-32 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily Astex_2179 a93540b0c2d4ee55e2e4c02db744767c 571 SUPERFAMILY SSF47336 504 551 1.07E-5 T 13-10-2018 IPR036736 ACP-like superfamily Astex_2179 a93540b0c2d4ee55e2e4c02db744767c 571 Gene3D G3DSA:3.40.50.12780 12 375 4.9E-55 T 13-10-2018 Astex_2179 a93540b0c2d4ee55e2e4c02db744767c 571 Pfam PF00501 AMP-binding enzyme 125 381 1.9E-44 T 13-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Astex_2179 a93540b0c2d4ee55e2e4c02db744767c 571 SUPERFAMILY SSF56801 12 469 3.27E-68 T 13-10-2018 Astex_2179 a93540b0c2d4ee55e2e4c02db744767c 571 Gene3D G3DSA:1.10.1200.10 500 561 4.1E-5 T 13-10-2018 IPR036736 ACP-like superfamily Astex_2179 a93540b0c2d4ee55e2e4c02db744767c 571 Pfam PF00550 Phosphopantetheine attachment site 509 558 4.9E-5 T 13-10-2018 IPR009081 Phosphopantetheine binding ACP domain Astex_3102 e9e80bb537d8fb67bd0880f2a8a6c40e 172 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 3 172 1.0E-47 T 13-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 Astex_3102 e9e80bb537d8fb67bd0880f2a8a6c40e 172 SUPERFAMILY SSF50249 4 172 8.91E-52 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Astex_3102 e9e80bb537d8fb67bd0880f2a8a6c40e 172 Hamap MF_00984 Single-stranded DNA-binding protein. 5 118 35.713 T 13-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 Astex_3102 e9e80bb537d8fb67bd0880f2a8a6c40e 172 Gene3D G3DSA:2.40.50.140 2 115 2.6E-48 T 13-10-2018 Astex_3102 e9e80bb537d8fb67bd0880f2a8a6c40e 172 Pfam PF00436 Single-strand binding protein family 5 107 3.6E-39 T 13-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 Astex_2361 83cf9d504546b72e7f0b35bad12d682a 220 Gene3D G3DSA:3.20.20.70 3 220 1.2E-57 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_2361 83cf9d504546b72e7f0b35bad12d682a 220 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 3 220 34.912 T 13-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 Astex_2361 83cf9d504546b72e7f0b35bad12d682a 220 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 5 215 6.5E-43 T 13-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 Astex_2361 83cf9d504546b72e7f0b35bad12d682a 220 SUPERFAMILY SSF51366 4 218 6.59E-50 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Astex_3497 107b9c6a073bc50ebcde6f6cddda6d00 140 SUPERFAMILY SSF52172 3 123 5.55E-20 T 13-10-2018 IPR011006 CheY-like superfamily Astex_3497 107b9c6a073bc50ebcde6f6cddda6d00 140 Pfam PF00072 Response regulator receiver domain 5 117 2.6E-13 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_3497 107b9c6a073bc50ebcde6f6cddda6d00 140 Gene3D G3DSA:3.40.50.2300 2 130 1.9E-19 T 13-10-2018 Astex_3497 107b9c6a073bc50ebcde6f6cddda6d00 140 SMART SM00448 3 120 3.8E-6 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_0806 6c97f1903f4ebba1bee6ee89d71b14ab 319 SUPERFAMILY SSF54826 2 105 1.93E-24 T 13-10-2018 Astex_0806 6c97f1903f4ebba1bee6ee89d71b14ab 319 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 4 102 4.8E-7 T 13-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain Astex_0806 6c97f1903f4ebba1bee6ee89d71b14ab 319 SMART SM00922 123 214 2.2E-14 T 13-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal Astex_0806 6c97f1903f4ebba1bee6ee89d71b14ab 319 SUPERFAMILY SSF51604 112 319 3.8E-53 T 13-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily Astex_0806 6c97f1903f4ebba1bee6ee89d71b14ab 319 Pfam PF13378 Enolase C-terminal domain-like 137 282 4.7E-26 T 13-10-2018 IPR029065 Enolase C-terminal domain-like Astex_0806 6c97f1903f4ebba1bee6ee89d71b14ab 319 Gene3D G3DSA:3.20.20.120 99 319 8.7E-58 T 13-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily Astex_0806 6c97f1903f4ebba1bee6ee89d71b14ab 319 Gene3D G3DSA:3.30.390.10 1 97 4.0E-23 T 13-10-2018 IPR029017 Enolase-like, N-terminal Astex_0806 6c97f1903f4ebba1bee6ee89d71b14ab 319 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 164 195 - T 13-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 Astex_0740 87f60a8624bb0e52f2b5652d1bc5f514 153 SUPERFAMILY SSF53041 68 107 5.62E-7 T 13-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 Astex_0740 87f60a8624bb0e52f2b5652d1bc5f514 153 Gene3D G3DSA:3.40.50.1390 43 111 2.6E-6 T 13-10-2018 Astex_0740 87f60a8624bb0e52f2b5652d1bc5f514 153 Gene3D G3DSA:1.10.10.60 112 149 7.1E-15 T 13-10-2018 Astex_0740 87f60a8624bb0e52f2b5652d1bc5f514 153 Pfam PF00239 Resolvase, N terminal domain 68 107 2.7E-7 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 Astex_0740 87f60a8624bb0e52f2b5652d1bc5f514 153 SUPERFAMILY SSF46689 109 148 3.67E-7 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Astex_0740 87f60a8624bb0e52f2b5652d1bc5f514 153 Pfam PF02796 Helix-turn-helix domain of resolvase 109 147 1.0E-7 T 13-10-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 Astex_2359 a957c78b878ad3cbf9ad135abfca83cd 272 SUPERFAMILY SSF51366 5 253 5.27E-88 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Astex_2359 a957c78b878ad3cbf9ad135abfca83cd 272 Gene3D G3DSA:3.20.20.70 2 271 5.4E-98 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_2359 a957c78b878ad3cbf9ad135abfca83cd 272 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 10 248 2.3E-76 T 13-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Astex_2359 a957c78b878ad3cbf9ad135abfca83cd 272 Pfam PF00290 Tryptophan synthase alpha chain 10 266 1.1E-92 T 13-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Astex_2359 a957c78b878ad3cbf9ad135abfca83cd 272 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 50 63 - T 13-10-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Astex_2359 a957c78b878ad3cbf9ad135abfca83cd 272 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 16 270 34.656 T 13-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 Astex_2499 b8e6dcd8d444d6c0b21a9f7a1a62c281 164 Gene3D G3DSA:1.10.10.10 98 160 5.1E-9 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_2499 b8e6dcd8d444d6c0b21a9f7a1a62c281 164 Gene3D G3DSA:1.10.1740.10 3 95 1.8E-11 T 13-10-2018 Astex_2499 b8e6dcd8d444d6c0b21a9f7a1a62c281 164 Pfam PF04542 Sigma-70 region 2 13 75 1.9E-12 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 Astex_2499 b8e6dcd8d444d6c0b21a9f7a1a62c281 164 Pfam PF08281 Sigma-70, region 4 103 153 1.3E-7 T 13-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Astex_2499 b8e6dcd8d444d6c0b21a9f7a1a62c281 164 SUPERFAMILY SSF88946 5 87 2.01E-14 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 Astex_2499 b8e6dcd8d444d6c0b21a9f7a1a62c281 164 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 15 154 2.0E-18 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 Astex_2499 b8e6dcd8d444d6c0b21a9f7a1a62c281 164 SUPERFAMILY SSF88659 99 157 1.44E-8 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Astex_3308 e02cf1d6c16b3e43f9827220df76019b 484 Gene3D G3DSA:3.50.50.60 6 473 7.9E-83 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_3308 e02cf1d6c16b3e43f9827220df76019b 484 Pfam PF04820 Tryptophan halogenase 8 440 3.5E-57 T 13-10-2018 IPR006905 Flavin-dependent halogenase Astex_3308 e02cf1d6c16b3e43f9827220df76019b 484 SUPERFAMILY SSF51905 6 381 9.84E-14 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_2306 06175f4923eff278bd52147322f79f4d 679 SUPERFAMILY SSF56317 15 295 3.01E-55 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily Astex_2306 06175f4923eff278bd52147322f79f4d 679 SUPERFAMILY SSF52402 326 645 6.9E-61 T 13-10-2018 Astex_2306 06175f4923eff278bd52147322f79f4d 679 Hamap MF_02090 Glutamine-dependent NAD(+) synthetase [nadE]. 17 669 28.125 T 13-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 Astex_2306 06175f4923eff278bd52147322f79f4d 679 Pfam PF00795 Carbon-nitrogen hydrolase 19 285 5.5E-22 T 13-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 Astex_2306 06175f4923eff278bd52147322f79f4d 679 Gene3D G3DSA:3.40.50.620 324 543 2.4E-60 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Astex_2306 06175f4923eff278bd52147322f79f4d 679 Gene3D G3DSA:1.10.10.1140 557 679 3.5E-47 T 13-10-2018 Astex_2306 06175f4923eff278bd52147322f79f4d 679 Gene3D G3DSA:3.60.110.10 6 309 5.0E-87 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily Astex_2306 06175f4923eff278bd52147322f79f4d 679 PIRSF PIRSF006630 14 669 5.8E-157 T 13-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 Astex_2306 06175f4923eff278bd52147322f79f4d 679 TIGRFAM TIGR00552 nadE: NAD+ synthetase 354 499 2.3E-18 T 13-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 Astex_2306 06175f4923eff278bd52147322f79f4d 679 Pfam PF02540 NAD synthase 349 571 6.4E-24 T 13-10-2018 IPR022310 NAD/GMP synthase Astex_1018 029f70cfbe89345af4033803c77c4ddc 404 Pfam PF16499 Alpha galactosidase A 44 312 4.1E-75 T 13-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Astex_1018 029f70cfbe89345af4033803c77c4ddc 404 Gene3D G3DSA:2.60.40.1180 315 403 6.0E-27 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta Astex_1018 029f70cfbe89345af4033803c77c4ddc 404 Pfam PF17450 Alpha galactosidase A C-terminal beta sandwich domain 315 379 5.6E-7 T 13-10-2018 IPR035373 Alpha galactosidase A, C-terminal beta-sandwich domain Astex_1018 029f70cfbe89345af4033803c77c4ddc 404 SUPERFAMILY SSF51445 36 313 3.05E-99 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_1018 029f70cfbe89345af4033803c77c4ddc 404 ProSitePatterns PS00512 Alpha-galactosidase signature. 79 94 - T 13-10-2018 IPR000111 Glycoside hydrolase family 27/36, conserved site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Astex_1018 029f70cfbe89345af4033803c77c4ddc 404 PRINTS PR00740 Glycosyl hydrolase family 27 signature 74 89 1.2E-55 T 13-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Astex_1018 029f70cfbe89345af4033803c77c4ddc 404 PRINTS PR00740 Glycosyl hydrolase family 27 signature 114 135 1.2E-55 T 13-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Astex_1018 029f70cfbe89345af4033803c77c4ddc 404 PRINTS PR00740 Glycosyl hydrolase family 27 signature 38 57 1.2E-55 T 13-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Astex_1018 029f70cfbe89345af4033803c77c4ddc 404 PRINTS PR00740 Glycosyl hydrolase family 27 signature 148 165 1.2E-55 T 13-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Astex_1018 029f70cfbe89345af4033803c77c4ddc 404 PRINTS PR00740 Glycosyl hydrolase family 27 signature 268 289 1.2E-55 T 13-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Astex_1018 029f70cfbe89345af4033803c77c4ddc 404 PRINTS PR00740 Glycosyl hydrolase family 27 signature 175 193 1.2E-55 T 13-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Astex_1018 029f70cfbe89345af4033803c77c4ddc 404 PRINTS PR00740 Glycosyl hydrolase family 27 signature 247 266 1.2E-55 T 13-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Astex_1018 029f70cfbe89345af4033803c77c4ddc 404 SUPERFAMILY SSF51011 314 402 9.0E-24 T 13-10-2018 Astex_1018 029f70cfbe89345af4033803c77c4ddc 404 Gene3D G3DSA:3.20.20.70 37 313 1.8E-125 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_1134 dc08f35c8433d32636f2195c28994ac1 242 Gene3D G3DSA:3.90.226.10 1 192 5.2E-49 T 13-10-2018 Astex_1134 dc08f35c8433d32636f2195c28994ac1 242 Gene3D G3DSA:1.10.12.10 195 239 6.0E-7 T 13-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal Astex_1134 dc08f35c8433d32636f2195c28994ac1 242 Pfam PF00378 Enoyl-CoA hydratase/isomerase 8 207 2.6E-37 T 13-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 Astex_1134 dc08f35c8433d32636f2195c28994ac1 242 SUPERFAMILY SSF52096 3 241 9.25E-58 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Astex_2872 0d498a7170ce208e1c5539f625d13ea4 327 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 7 292 1.8E-93 T 13-10-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 Astex_2872 0d498a7170ce208e1c5539f625d13ea4 327 Gene3D G3DSA:3.20.20.70 11 252 2.4E-69 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_2872 0d498a7170ce208e1c5539f625d13ea4 327 Pfam PF01207 Dihydrouridine synthase (Dus) 18 295 3.5E-91 T 13-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 Astex_2872 0d498a7170ce208e1c5539f625d13ea4 327 PIRSF PIRSF006621 4 327 2.0E-95 T 13-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 Astex_2872 0d498a7170ce208e1c5539f625d13ea4 327 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 98 116 - T 13-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 Astex_2872 0d498a7170ce208e1c5539f625d13ea4 327 SUPERFAMILY SSF51395 16 289 2.2E-76 T 13-10-2018 Astex_2956 6773738da32f69d001fcda50547afa5c 738 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 649 686 4.4E-5 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Astex_2956 6773738da32f69d001fcda50547afa5c 738 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 552 597 0.46 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Astex_2956 6773738da32f69d001fcda50547afa5c 738 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 606 633 4.7 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Astex_2956 6773738da32f69d001fcda50547afa5c 738 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 37 469 6.2E-143 T 13-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Astex_2956 6773738da32f69d001fcda50547afa5c 738 SUPERFAMILY SSF56719 36 489 3.79E-158 T 13-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 Astex_2956 6773738da32f69d001fcda50547afa5c 738 Gene3D G3DSA:2.120.10.90 508 723 6.7E-17 T 13-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal Astex_2956 6773738da32f69d001fcda50547afa5c 738 SUPERFAMILY SSF101904 507 734 4.97E-47 T 13-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal Astex_2956 6773738da32f69d001fcda50547afa5c 738 Hamap MF_00936 DNA topoisomerase 4 subunit A [parC]. 9 738 31.538 T 13-10-2018 IPR005742 DNA topoisomerase IV, subunit A, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 Astex_2956 6773738da32f69d001fcda50547afa5c 738 TIGRFAM TIGR01062 parC_Gneg: DNA topoisomerase IV, A subunit 18 735 1.5E-257 T 13-10-2018 Astex_2956 6773738da32f69d001fcda50547afa5c 738 SMART SM00434 16 468 6.5E-243 T 13-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Astex_2956 6773738da32f69d001fcda50547afa5c 738 Gene3D G3DSA:3.30.1360.40 242 338 2.6E-185 T 13-10-2018 Astex_2956 6773738da32f69d001fcda50547afa5c 738 Gene3D G3DSA:3.90.199.10 37 489 2.6E-185 T 13-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 Astex_2956 6773738da32f69d001fcda50547afa5c 738 Gene3D G3DSA:1.10.268.10 376 461 2.6E-185 T 13-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 Astex_0005 e0cf27128adc4be20b615886bef152fc 122 Gene3D G3DSA:1.10.260.40 52 120 2.0E-5 T 13-10-2018 Astex_0005 e0cf27128adc4be20b615886bef152fc 122 SUPERFAMILY SSF47413 60 115 1.76E-6 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Astex_1258 82950683a4626b4112d9aa8b39e57a19 132 Gene3D G3DSA:3.30.1390.10 25 132 1.9E-42 T 13-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like Astex_1258 82950683a4626b4112d9aa8b39e57a19 132 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 50 128 2.5E-35 T 13-10-2018 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 Astex_1258 82950683a4626b4112d9aa8b39e57a19 132 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 44 127 28.598 T 13-10-2018 IPR022935 ATP-dependent Clp protease adaptor protein ClpS Astex_1258 82950683a4626b4112d9aa8b39e57a19 132 SUPERFAMILY SSF54736 48 131 1.41E-32 T 13-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like Astex_1926 fd911535d8a86f8b909f98e78b06b743 282 SUPERFAMILY SSF55781 94 274 1.18E-52 T 13-10-2018 Astex_1926 fd911535d8a86f8b909f98e78b06b743 282 Pfam PF09339 IclR helix-turn-helix domain 31 80 6.9E-14 T 13-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Astex_1926 fd911535d8a86f8b909f98e78b06b743 282 SMART SM00346 29 118 4.5E-20 T 13-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Astex_1926 fd911535d8a86f8b909f98e78b06b743 282 Pfam PF01614 Bacterial transcriptional regulator 147 269 4.7E-36 T 13-10-2018 IPR014757 Transcription regulator IclR, C-terminal Astex_1926 fd911535d8a86f8b909f98e78b06b743 282 Gene3D G3DSA:3.30.450.40 103 276 3.2E-58 T 13-10-2018 IPR029016 GAF-like domain superfamily Astex_1926 fd911535d8a86f8b909f98e78b06b743 282 Gene3D G3DSA:1.10.10.10 28 102 5.9E-18 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1926 fd911535d8a86f8b909f98e78b06b743 282 SUPERFAMILY SSF46785 30 101 4.17E-14 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_2023 3c7e6a66da730396b441c6921e53a0ce 624 Pfam PF00005 ABC transporter 318 453 9.3E-25 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_2023 3c7e6a66da730396b441c6921e53a0ce 624 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Astex_2023 3c7e6a66da730396b441c6921e53a0ce 624 SUPERFAMILY SSF52540 24 224 1.0E-41 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2023 3c7e6a66da730396b441c6921e53a0ce 624 ProSitePatterns PS00211 ABC transporters family signature. 425 439 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Astex_2023 3c7e6a66da730396b441c6921e53a0ce 624 Pfam PF16326 ABC transporter C-terminal domain 548 617 2.0E-15 T 13-10-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 Astex_2023 3c7e6a66da730396b441c6921e53a0ce 624 Gene3D G3DSA:3.40.50.300 265 534 4.7E-62 T 13-10-2018 Astex_2023 3c7e6a66da730396b441c6921e53a0ce 624 Gene3D G3DSA:3.40.50.300 12 247 7.5E-48 T 13-10-2018 Astex_2023 3c7e6a66da730396b441c6921e53a0ce 624 SUPERFAMILY SSF52540 297 503 1.22E-48 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2023 3c7e6a66da730396b441c6921e53a0ce 624 Gene3D G3DSA:1.10.287.380 538 621 6.7E-14 T 13-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 Astex_2023 3c7e6a66da730396b441c6921e53a0ce 624 Pfam PF00005 ABC transporter 45 167 1.8E-18 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_2023 3c7e6a66da730396b441c6921e53a0ce 624 SMART SM00382 327 499 1.0E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_2023 3c7e6a66da730396b441c6921e53a0ce 624 SMART SM00382 53 219 1.7E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_1376 68672867a3fd48b025ef5f5b91bbe2dd 189 Gene3D G3DSA:1.10.1740.10 2 80 1.4E-7 T 13-10-2018 Astex_1376 68672867a3fd48b025ef5f5b91bbe2dd 189 SUPERFAMILY SSF88659 94 164 2.24E-11 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Astex_1376 68672867a3fd48b025ef5f5b91bbe2dd 189 Pfam PF04542 Sigma-70 region 2 28 79 8.1E-10 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 Astex_1376 68672867a3fd48b025ef5f5b91bbe2dd 189 SUPERFAMILY SSF88946 15 83 7.85E-11 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 Astex_1376 68672867a3fd48b025ef5f5b91bbe2dd 189 Pfam PF08281 Sigma-70, region 4 113 161 1.1E-11 T 13-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Astex_1376 68672867a3fd48b025ef5f5b91bbe2dd 189 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 32 166 7.6E-22 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 Astex_1376 68672867a3fd48b025ef5f5b91bbe2dd 189 Gene3D G3DSA:1.10.10.10 87 172 5.5E-14 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_0902 8512cf01f751044f89bcc4b8922ff048 334 SUPERFAMILY SSF143865 15 272 2.35E-34 T 13-10-2018 Astex_0902 8512cf01f751044f89bcc4b8922ff048 334 Gene3D G3DSA:1.20.58.340 258 334 3.2E-24 T 13-10-2018 Astex_0902 8512cf01f751044f89bcc4b8922ff048 334 Gene3D G3DSA:3.30.460.20 25 138 3.9E-5 T 13-10-2018 Astex_0902 8512cf01f751044f89bcc4b8922ff048 334 SUPERFAMILY SSF144083 269 331 5.89E-19 T 13-10-2018 Astex_0902 8512cf01f751044f89bcc4b8922ff048 334 Pfam PF01544 CorA-like Mg2+ transporter protein 36 329 1.3E-49 T 13-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 Astex_2150 58735e4ca6c92181ba92f044cada6e34 313 Gene3D G3DSA:2.60.120.620 8 294 1.9E-10 T 13-10-2018 Astex_2150 58735e4ca6c92181ba92f044cada6e34 313 SUPERFAMILY SSF51197 70 301 5.63E-17 T 13-10-2018 Astex_2150 58735e4ca6c92181ba92f044cada6e34 313 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 80 267 5.5E-6 T 13-10-2018 IPR008775 Phytanoyl-CoA dioxygenase Astex_0988 667bc82eff55925ccea3b4f6498d0bd9 690 Pfam PF00326 Prolyl oligopeptidase family 479 688 7.4E-56 T 13-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 Astex_0988 667bc82eff55925ccea3b4f6498d0bd9 690 Gene3D G3DSA:2.120.10.30 186 407 6.4E-22 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like Astex_0988 667bc82eff55925ccea3b4f6498d0bd9 690 Pfam PF07676 WD40-like Beta Propeller Repeat 227 262 0.0021 T 13-10-2018 IPR011659 WD40-like Beta Propeller Astex_0988 667bc82eff55925ccea3b4f6498d0bd9 690 Gene3D G3DSA:2.120.10.30 50 175 6.2E-13 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like Astex_0988 667bc82eff55925ccea3b4f6498d0bd9 690 SUPERFAMILY SSF53474 433 687 2.75E-64 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_0988 667bc82eff55925ccea3b4f6498d0bd9 690 Gene3D G3DSA:3.40.50.1820 419 690 6.8E-60 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_0988 667bc82eff55925ccea3b4f6498d0bd9 690 SUPERFAMILY SSF82171 38 421 3.34E-33 T 13-10-2018 Astex_3043 26d98cd1e5a644e64fc22e06fd489d77 422 Pfam PF04264 YceI-like domain 261 419 1.3E-28 T 13-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like Astex_3043 26d98cd1e5a644e64fc22e06fd489d77 422 Pfam PF01292 Prokaryotic cytochrome b561 6 175 4.8E-25 T 13-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 Astex_3043 26d98cd1e5a644e64fc22e06fd489d77 422 SUPERFAMILY SSF101874 261 420 1.83E-38 T 13-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily Astex_3043 26d98cd1e5a644e64fc22e06fd489d77 422 SUPERFAMILY SSF81342 3 179 2.9E-27 T 13-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 Astex_3043 26d98cd1e5a644e64fc22e06fd489d77 422 SMART SM00867 260 420 2.4E-39 T 13-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like Astex_3043 26d98cd1e5a644e64fc22e06fd489d77 422 Gene3D G3DSA:2.40.128.110 260 422 7.7E-36 T 13-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily Astex_2398 56cec9377b25a3a8ade35c63b951813e 935 Pfam PF07715 TonB-dependent Receptor Plug Domain 154 278 2.9E-6 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_2398 56cec9377b25a3a8ade35c63b951813e 935 SUPERFAMILY SSF56935 152 935 7.78E-40 T 13-10-2018 Astex_2398 56cec9377b25a3a8ade35c63b951813e 935 SMART SM00965 62 112 4.7E-13 T 13-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 Astex_2398 56cec9377b25a3a8ade35c63b951813e 935 Pfam PF07660 Secretin and TonB N terminus short domain 63 109 4.0E-13 T 13-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 Astex_2398 56cec9377b25a3a8ade35c63b951813e 935 Gene3D G3DSA:2.170.130.10 132 284 1.3E-5 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_2398 56cec9377b25a3a8ade35c63b951813e 935 Gene3D G3DSA:3.55.50.30 30 131 8.5E-28 T 13-10-2018 Astex_1556 a2dbe28f26c8218fb3aaa3d42844d4f0 111 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 10 98 1.3E-34 T 13-10-2018 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 Astex_0017 7abea38e0b24b1d4800c77469af765e0 219 Pfam PF00834 Ribulose-phosphate 3 epimerase family 6 202 6.1E-81 T 13-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 Astex_0017 7abea38e0b24b1d4800c77469af765e0 219 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 6 217 1.1E-85 T 13-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 Astex_0017 7abea38e0b24b1d4800c77469af765e0 219 PIRSF PIRSF001461 1 218 6.8E-88 T 13-10-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 Astex_0017 7abea38e0b24b1d4800c77469af765e0 219 Gene3D G3DSA:3.20.20.70 1 218 2.1E-79 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_0017 7abea38e0b24b1d4800c77469af765e0 219 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 33 47 - T 13-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 Astex_0017 7abea38e0b24b1d4800c77469af765e0 219 SUPERFAMILY SSF51366 2 216 4.24E-71 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Astex_0017 7abea38e0b24b1d4800c77469af765e0 219 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 135 157 - T 13-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 Astex_3167 805316a2b5d20c4038c78b3ed0bfac71 309 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Astex_3167 805316a2b5d20c4038c78b3ed0bfac71 309 SMART SM00382 31 209 1.1E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_3167 805316a2b5d20c4038c78b3ed0bfac71 309 Gene3D G3DSA:3.40.50.300 1 230 2.5E-54 T 13-10-2018 Astex_3167 805316a2b5d20c4038c78b3ed0bfac71 309 Pfam PF00005 ABC transporter 23 161 3.4E-22 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_3167 805316a2b5d20c4038c78b3ed0bfac71 309 SUPERFAMILY SSF52540 5 223 3.62E-53 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0721 baa9a79ef36e7046f2ccc295d25e1f6a 208 Pfam PF13462 Thioredoxin 40 195 4.7E-16 T 13-10-2018 IPR012336 Thioredoxin-like fold Astex_0721 baa9a79ef36e7046f2ccc295d25e1f6a 208 Gene3D G3DSA:3.40.30.10 32 201 5.0E-35 T 13-10-2018 Astex_0721 baa9a79ef36e7046f2ccc295d25e1f6a 208 SUPERFAMILY SSF52833 32 186 1.17E-32 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Astex_3719 9b5888996f905ad8d6f07e287ec38dab 390 Gene3D G3DSA:1.20.81.30 255 356 1.2E-16 T 13-10-2018 Astex_3719 9b5888996f905ad8d6f07e287ec38dab 390 Gene3D G3DSA:1.20.81.30 54 160 2.7E-12 T 13-10-2018 Astex_3719 9b5888996f905ad8d6f07e287ec38dab 390 PRINTS PR00812 Bacterial general secretion pathway protein F signature 151 179 8.8E-7 T 13-10-2018 IPR003004 GspF/PilC family Astex_3719 9b5888996f905ad8d6f07e287ec38dab 390 PRINTS PR00812 Bacterial general secretion pathway protein F signature 353 367 8.8E-7 T 13-10-2018 IPR003004 GspF/PilC family Astex_3719 9b5888996f905ad8d6f07e287ec38dab 390 PRINTS PR00812 Bacterial general secretion pathway protein F signature 58 70 8.8E-7 T 13-10-2018 IPR003004 GspF/PilC family Astex_3719 9b5888996f905ad8d6f07e287ec38dab 390 Pfam PF00482 Type II secretion system (T2SS), protein F 63 179 9.1E-13 T 13-10-2018 IPR018076 Type II secretion system F domain Astex_3719 9b5888996f905ad8d6f07e287ec38dab 390 Pfam PF00482 Type II secretion system (T2SS), protein F 258 379 2.6E-19 T 13-10-2018 IPR018076 Type II secretion system F domain Astex_2771 2edffbfc87506945c235ee531adee47a 352 Gene3D G3DSA:3.30.70.270 167 344 8.4E-49 T 13-10-2018 Astex_2771 2edffbfc87506945c235ee531adee47a 352 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 180 341 6.2E-41 T 13-10-2018 IPR000160 GGDEF domain Astex_2771 2edffbfc87506945c235ee531adee47a 352 Pfam PF00990 Diguanylate cyclase, GGDEF domain 181 337 9.8E-41 T 13-10-2018 IPR000160 GGDEF domain Astex_2771 2edffbfc87506945c235ee531adee47a 352 SMART SM00267 170 342 9.1E-48 T 13-10-2018 IPR000160 GGDEF domain Astex_2771 2edffbfc87506945c235ee531adee47a 352 SUPERFAMILY SSF55073 186 341 2.75E-40 T 13-10-2018 IPR029787 Nucleotide cyclase Astex_1930 b03533507cb816b9f8db27604e9509b0 568 PRINTS PR00745 Glycosyl hydrolase family 39 signature 513 527 5.3E-9 T 13-10-2018 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101|Reactome: R-HSA-2206302 Astex_1930 b03533507cb816b9f8db27604e9509b0 568 PRINTS PR00745 Glycosyl hydrolase family 39 signature 275 289 5.3E-9 T 13-10-2018 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101|Reactome: R-HSA-2206302 Astex_1930 b03533507cb816b9f8db27604e9509b0 568 PRINTS PR00745 Glycosyl hydrolase family 39 signature 502 513 5.3E-9 T 13-10-2018 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101|Reactome: R-HSA-2206302 Astex_1930 b03533507cb816b9f8db27604e9509b0 568 PRINTS PR00745 Glycosyl hydrolase family 39 signature 127 143 5.3E-9 T 13-10-2018 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101|Reactome: R-HSA-2206302 Astex_1930 b03533507cb816b9f8db27604e9509b0 568 SUPERFAMILY SSF51011 416 567 1.29E-25 T 13-10-2018 Astex_1930 b03533507cb816b9f8db27604e9509b0 568 Pfam PF01229 Glycosyl hydrolases family 39 34 566 4.2E-52 T 13-10-2018 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101|Reactome: R-HSA-2206302 Astex_1930 b03533507cb816b9f8db27604e9509b0 568 ProSitePatterns PS01027 Glycosyl hydrolases family 39 active site. 207 216 - T 13-10-2018 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101|Reactome: R-HSA-2206302 Astex_1930 b03533507cb816b9f8db27604e9509b0 568 Gene3D G3DSA:2.60.40.1500 438 568 3.5E-28 T 13-10-2018 Astex_1930 b03533507cb816b9f8db27604e9509b0 568 Gene3D G3DSA:3.20.20.80 53 425 3.1E-77 T 13-10-2018 Astex_1930 b03533507cb816b9f8db27604e9509b0 568 SUPERFAMILY SSF51445 47 425 7.48E-42 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_2401 5c0a265c0a581c7c0b1c65b1585623b4 171 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 6 160 6.0E-27 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 Astex_2401 5c0a265c0a581c7c0b1c65b1585623b4 171 SUPERFAMILY SSF88659 84 166 4.36E-15 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Astex_2401 5c0a265c0a581c7c0b1c65b1585623b4 171 Gene3D G3DSA:1.10.10.10 88 168 3.9E-17 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_2401 5c0a265c0a581c7c0b1c65b1585623b4 171 Pfam PF04542 Sigma-70 region 2 9 76 1.1E-10 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 Astex_2401 5c0a265c0a581c7c0b1c65b1585623b4 171 Gene3D G3DSA:1.10.1740.10 2 72 2.6E-13 T 13-10-2018 Astex_2401 5c0a265c0a581c7c0b1c65b1585623b4 171 Pfam PF08281 Sigma-70, region 4 110 159 2.4E-15 T 13-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Astex_2401 5c0a265c0a581c7c0b1c65b1585623b4 171 SUPERFAMILY SSF88946 4 79 6.67E-16 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 Astex_2798 0b75d995aa70e65b6d053039eb907323 92 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 1.8E-9 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Astex_2798 0b75d995aa70e65b6d053039eb907323 92 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 1.8E-9 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Astex_2798 0b75d995aa70e65b6d053039eb907323 92 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 1.8E-9 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Astex_2798 0b75d995aa70e65b6d053039eb907323 92 Pfam PF00216 Bacterial DNA-binding protein 3 91 4.3E-30 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Astex_2798 0b75d995aa70e65b6d053039eb907323 92 SUPERFAMILY SSF47729 3 91 9.42E-29 T 13-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 Astex_2798 0b75d995aa70e65b6d053039eb907323 92 SMART SM00411 2 91 3.1E-35 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 Astex_2798 0b75d995aa70e65b6d053039eb907323 92 Gene3D G3DSA:4.10.520.10 2 92 5.8E-30 T 13-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 Astex_0004 6c6d54378a49d18aa6069a0b6b86cca8 815 Pfam PF01751 Toprim domain 443 555 2.4E-18 T 13-10-2018 IPR006171 TOPRIM domain Astex_0004 6c6d54378a49d18aa6069a0b6b86cca8 815 Gene3D G3DSA:3.40.50.670 720 814 9.8E-22 T 13-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Astex_0004 6c6d54378a49d18aa6069a0b6b86cca8 815 SUPERFAMILY SSF54211 245 415 2.47E-57 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Astex_0004 6c6d54378a49d18aa6069a0b6b86cca8 815 SMART SM00433 45 809 5.8E-251 T 13-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Astex_0004 6c6d54378a49d18aa6069a0b6b86cca8 815 SMART SM00387 41 192 9.5E-26 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_0004 6c6d54378a49d18aa6069a0b6b86cca8 815 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 42 162 4.4E-19 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_0004 6c6d54378a49d18aa6069a0b6b86cca8 815 PRINTS PR01159 DNA gyrase subunit B signature 769 781 1.2E-65 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Astex_0004 6c6d54378a49d18aa6069a0b6b86cca8 815 PRINTS PR01159 DNA gyrase subunit B signature 244 266 1.2E-65 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Astex_0004 6c6d54378a49d18aa6069a0b6b86cca8 815 PRINTS PR01159 DNA gyrase subunit B signature 218 231 1.2E-65 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Astex_0004 6c6d54378a49d18aa6069a0b6b86cca8 815 PRINTS PR01159 DNA gyrase subunit B signature 336 352 1.2E-65 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Astex_0004 6c6d54378a49d18aa6069a0b6b86cca8 815 PRINTS PR01159 DNA gyrase subunit B signature 203 218 1.2E-65 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Astex_0004 6c6d54378a49d18aa6069a0b6b86cca8 815 PRINTS PR01159 DNA gyrase subunit B signature 494 503 1.2E-65 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Astex_0004 6c6d54378a49d18aa6069a0b6b86cca8 815 PRINTS PR01159 DNA gyrase subunit B signature 398 418 1.2E-65 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Astex_0004 6c6d54378a49d18aa6069a0b6b86cca8 815 PRINTS PR01159 DNA gyrase subunit B signature 384 398 1.2E-65 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Astex_0004 6c6d54378a49d18aa6069a0b6b86cca8 815 PRINTS PR01159 DNA gyrase subunit B signature 785 801 1.2E-65 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Astex_0004 6c6d54378a49d18aa6069a0b6b86cca8 815 PRINTS PR01159 DNA gyrase subunit B signature 15 25 1.2E-65 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 Astex_0004 6c6d54378a49d18aa6069a0b6b86cca8 815 SUPERFAMILY SSF55874 15 233 1.31E-63 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_0004 6c6d54378a49d18aa6069a0b6b86cca8 815 PRINTS PR00418 DNA topoisomerase II family signature 45 60 1.3E-71 T 13-10-2018 Astex_0004 6c6d54378a49d18aa6069a0b6b86cca8 815 PRINTS PR00418 DNA topoisomerase II family signature 529 546 1.3E-71 T 13-10-2018 Astex_0004 6c6d54378a49d18aa6069a0b6b86cca8 815 PRINTS PR00418 DNA topoisomerase II family signature 292 305 1.3E-71 T 13-10-2018 Astex_0004 6c6d54378a49d18aa6069a0b6b86cca8 815 PRINTS PR00418 DNA topoisomerase II family signature 444 458 1.3E-71 T 13-10-2018 Astex_0004 6c6d54378a49d18aa6069a0b6b86cca8 815 PRINTS PR00418 DNA topoisomerase II family signature 549 561 1.3E-71 T 13-10-2018 Astex_0004 6c6d54378a49d18aa6069a0b6b86cca8 815 PRINTS PR00418 DNA topoisomerase II family signature 511 527 1.3E-71 T 13-10-2018 Astex_0004 6c6d54378a49d18aa6069a0b6b86cca8 815 PRINTS PR00418 DNA topoisomerase II family signature 123 137 1.3E-71 T 13-10-2018 Astex_0004 6c6d54378a49d18aa6069a0b6b86cca8 815 PRINTS PR00418 DNA topoisomerase II family signature 748 764 1.3E-71 T 13-10-2018 Astex_0004 6c6d54378a49d18aa6069a0b6b86cca8 815 PRINTS PR00418 DNA topoisomerase II family signature 80 93 1.3E-71 T 13-10-2018 Astex_0004 6c6d54378a49d18aa6069a0b6b86cca8 815 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 12 815 101.344 T 13-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 Astex_0004 6c6d54378a49d18aa6069a0b6b86cca8 815 Pfam PF00204 DNA gyrase B 245 414 2.7E-59 T 13-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Astex_0004 6c6d54378a49d18aa6069a0b6b86cca8 815 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 744 805 1.1E-26 T 13-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Astex_0004 6c6d54378a49d18aa6069a0b6b86cca8 815 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 15 811 2.9E-289 T 13-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 Astex_0004 6c6d54378a49d18aa6069a0b6b86cca8 815 Gene3D G3DSA:3.30.230.10 245 416 2.1E-69 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Astex_0004 6c6d54378a49d18aa6069a0b6b86cca8 815 Gene3D G3DSA:3.40.50.670 422 605 8.8E-75 T 13-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Astex_0004 6c6d54378a49d18aa6069a0b6b86cca8 815 ProSitePatterns PS00177 DNA topoisomerase II signature. 446 454 - T 13-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Astex_0004 6c6d54378a49d18aa6069a0b6b86cca8 815 SUPERFAMILY SSF56719 418 810 7.85E-85 T 13-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 Astex_0004 6c6d54378a49d18aa6069a0b6b86cca8 815 Gene3D G3DSA:3.30.565.10 11 244 2.7E-80 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_1042 9d338a49bd2cfdccbc1b0bb31a6fce28 239 SUPERFAMILY SSF54719 124 238 1.83E-44 T 13-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Astex_1042 9d338a49bd2cfdccbc1b0bb31a6fce28 239 PRINTS PR01703 Manganese superoxide dismutase signature 102 115 6.1E-24 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Astex_1042 9d338a49bd2cfdccbc1b0bb31a6fce28 239 PRINTS PR01703 Manganese superoxide dismutase signature 60 73 6.1E-24 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Astex_1042 9d338a49bd2cfdccbc1b0bb31a6fce28 239 PRINTS PR01703 Manganese superoxide dismutase signature 156 164 6.1E-24 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Astex_1042 9d338a49bd2cfdccbc1b0bb31a6fce28 239 PRINTS PR01703 Manganese superoxide dismutase signature 197 209 6.1E-24 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Astex_1042 9d338a49bd2cfdccbc1b0bb31a6fce28 239 PRINTS PR01703 Manganese superoxide dismutase signature 39 50 6.1E-24 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Astex_1042 9d338a49bd2cfdccbc1b0bb31a6fce28 239 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 36 118 2.0E-29 T 13-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Astex_1042 9d338a49bd2cfdccbc1b0bb31a6fce28 239 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 199 206 - T 13-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Astex_1042 9d338a49bd2cfdccbc1b0bb31a6fce28 239 Gene3D G3DSA:1.10.287.990 53 119 2.3E-26 T 13-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Astex_1042 9d338a49bd2cfdccbc1b0bb31a6fce28 239 PIRSF PIRSF000349 8 239 6.8E-83 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Astex_1042 9d338a49bd2cfdccbc1b0bb31a6fce28 239 Gene3D G3DSA:2.40.500.20 121 239 2.7E-49 T 13-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Astex_1042 9d338a49bd2cfdccbc1b0bb31a6fce28 239 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 127 232 3.4E-40 T 13-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Astex_1042 9d338a49bd2cfdccbc1b0bb31a6fce28 239 SUPERFAMILY SSF46609 34 120 2.36E-33 T 13-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 Astex_2466 163a0c75b591488351e5bb9d77952df3 277 Gene3D G3DSA:3.40.830.10 5 277 4.4E-90 T 13-10-2018 Astex_2466 163a0c75b591488351e5bb9d77952df3 277 PIRSF PIRSF006157 9 277 4.9E-88 T 13-10-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 Astex_2466 163a0c75b591488351e5bb9d77952df3 277 SUPERFAMILY SSF53213 13 272 2.49E-83 T 13-10-2018 Astex_2466 163a0c75b591488351e5bb9d77952df3 277 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 16 271 9.7E-39 T 13-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 Astex_3020 508016d3ccb73623fa5601c3a8b83bce 191 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 4 190 29.677 T 13-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 Astex_3020 508016d3ccb73623fa5601c3a8b83bce 191 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 136 159 - T 13-10-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Astex_3020 508016d3ccb73623fa5601c3a8b83bce 191 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 4 189 7.1E-65 T 13-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 Astex_3020 508016d3ccb73623fa5601c3a8b83bce 191 Pfam PF00551 Formyl transferase 4 184 5.0E-56 T 13-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Astex_3020 508016d3ccb73623fa5601c3a8b83bce 191 SUPERFAMILY SSF53328 4 189 7.2E-59 T 13-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 Astex_3020 508016d3ccb73623fa5601c3a8b83bce 191 Gene3D G3DSA:3.40.50.170 1 191 1.7E-72 T 13-10-2018 Astex_0706 f9ee8129d9410c54a8925bf4f2ccf364 89 SUPERFAMILY SSF69786 3 82 1.11E-22 T 13-10-2018 IPR036591 YggU-like superfamily Astex_0706 f9ee8129d9410c54a8925bf4f2ccf364 89 Pfam PF02594 Uncharacterised ACR, YggU family COG1872 3 78 1.1E-25 T 13-10-2018 IPR003746 Protein of unknown function DUF167 Astex_0706 f9ee8129d9410c54a8925bf4f2ccf364 89 Gene3D G3DSA:3.30.1200.10 2 88 5.2E-25 T 13-10-2018 IPR036591 YggU-like superfamily Astex_0706 f9ee8129d9410c54a8925bf4f2ccf364 89 Hamap MF_00634 UPF0235 protein YggU [yggU]. 2 87 18.251 T 13-10-2018 IPR003746 Protein of unknown function DUF167 Astex_0706 f9ee8129d9410c54a8925bf4f2ccf364 89 SMART SM01152 2 79 1.8E-31 T 13-10-2018 IPR003746 Protein of unknown function DUF167 Astex_3397 e83a5fb5b439397b4d64cb858b88e607 304 PIRSF PIRSF001365 1 301 1.6E-78 T 13-10-2018 IPR002220 DapA-like GO:0016829 Astex_3397 e83a5fb5b439397b4d64cb858b88e607 304 SUPERFAMILY SSF51569 3 290 3.04E-81 T 13-10-2018 Astex_3397 e83a5fb5b439397b4d64cb858b88e607 304 Pfam PF00701 Dihydrodipicolinate synthetase family 6 290 1.1E-56 T 13-10-2018 IPR002220 DapA-like GO:0016829 Astex_3397 e83a5fb5b439397b4d64cb858b88e607 304 SMART SM01130 4 292 2.0E-86 T 13-10-2018 IPR002220 DapA-like GO:0016829 Astex_3397 e83a5fb5b439397b4d64cb858b88e607 304 PRINTS PR00146 Dihydrodipicolinate synthase signature 131 148 1.6E-9 T 13-10-2018 IPR002220 DapA-like GO:0016829 Astex_3397 e83a5fb5b439397b4d64cb858b88e607 304 PRINTS PR00146 Dihydrodipicolinate synthase signature 38 59 1.6E-9 T 13-10-2018 IPR002220 DapA-like GO:0016829 Astex_3397 e83a5fb5b439397b4d64cb858b88e607 304 PRINTS PR00146 Dihydrodipicolinate synthase signature 74 92 1.6E-9 T 13-10-2018 IPR002220 DapA-like GO:0016829 Astex_3397 e83a5fb5b439397b4d64cb858b88e607 304 Gene3D G3DSA:3.20.20.70 1 296 9.8E-83 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_2591 e83a5fb5b439397b4d64cb858b88e607 304 PIRSF PIRSF001365 1 301 1.6E-78 T 13-10-2018 IPR002220 DapA-like GO:0016829 Astex_2591 e83a5fb5b439397b4d64cb858b88e607 304 SUPERFAMILY SSF51569 3 290 3.04E-81 T 13-10-2018 Astex_2591 e83a5fb5b439397b4d64cb858b88e607 304 Pfam PF00701 Dihydrodipicolinate synthetase family 6 290 1.1E-56 T 13-10-2018 IPR002220 DapA-like GO:0016829 Astex_2591 e83a5fb5b439397b4d64cb858b88e607 304 SMART SM01130 4 292 2.0E-86 T 13-10-2018 IPR002220 DapA-like GO:0016829 Astex_2591 e83a5fb5b439397b4d64cb858b88e607 304 PRINTS PR00146 Dihydrodipicolinate synthase signature 131 148 1.6E-9 T 13-10-2018 IPR002220 DapA-like GO:0016829 Astex_2591 e83a5fb5b439397b4d64cb858b88e607 304 PRINTS PR00146 Dihydrodipicolinate synthase signature 38 59 1.6E-9 T 13-10-2018 IPR002220 DapA-like GO:0016829 Astex_2591 e83a5fb5b439397b4d64cb858b88e607 304 PRINTS PR00146 Dihydrodipicolinate synthase signature 74 92 1.6E-9 T 13-10-2018 IPR002220 DapA-like GO:0016829 Astex_2591 e83a5fb5b439397b4d64cb858b88e607 304 Gene3D G3DSA:3.20.20.70 1 296 9.8E-83 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_1535 ef7bd5dc142e11e8721b0cbef6d7f353 184 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 107 166 6.8E-7 T 13-10-2018 IPR037682 TonB, C-terminal GO:0055085 Astex_1658 0b2722780bfa163534b5673a21e624cc 297 Gene3D G3DSA:1.10.3720.10 36 293 2.2E-62 T 13-10-2018 IPR035906 MetI-like superfamily Astex_1658 0b2722780bfa163534b5673a21e624cc 297 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 27 288 9.7E-94 T 13-10-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 Astex_1658 0b2722780bfa163534b5673a21e624cc 297 TIGRFAM TIGR02139 permease_CysT: sulfate ABC transporter, permease protein CysT 30 293 4.7E-118 T 13-10-2018 IPR011865 Sulphate ABC transporter, permease protein CysT GO:0008272|GO:0015116|GO:0016021 Astex_1658 0b2722780bfa163534b5673a21e624cc 297 SUPERFAMILY SSF161098 37 286 1.05E-51 T 13-10-2018 IPR035906 MetI-like superfamily Astex_1658 0b2722780bfa163534b5673a21e624cc 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 294 1.4E-18 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Astex_0986 d6646dcfee16771b73a7b7a591ead1de 538 Pfam PF08238 Sel1 repeat 445 480 9.0E-8 T 13-10-2018 IPR006597 Sel1-like repeat Astex_0986 d6646dcfee16771b73a7b7a591ead1de 538 Gene3D G3DSA:1.25.40.10 399 533 2.9E-16 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_0986 d6646dcfee16771b73a7b7a591ead1de 538 SMART SM00671 445 480 4.1E-9 T 13-10-2018 IPR006597 Sel1-like repeat Astex_0986 d6646dcfee16771b73a7b7a591ead1de 538 SMART SM00671 481 518 100.0 T 13-10-2018 IPR006597 Sel1-like repeat Astex_0986 d6646dcfee16771b73a7b7a591ead1de 538 SUPERFAMILY SSF81901 436 506 2.22E-12 T 13-10-2018 Astex_2234 b05f67b7c9d12f8f0f4a59fa004146c0 267 Pfam PF08281 Sigma-70, region 4 195 241 1.3E-12 T 13-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Astex_2234 b05f67b7c9d12f8f0f4a59fa004146c0 267 SUPERFAMILY SSF88659 187 250 5.05E-12 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Astex_2234 b05f67b7c9d12f8f0f4a59fa004146c0 267 Gene3D G3DSA:1.10.260.40 8 81 5.9E-12 T 13-10-2018 Astex_2234 b05f67b7c9d12f8f0f4a59fa004146c0 267 Pfam PF12844 Helix-turn-helix domain 17 79 9.4E-9 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Astex_2234 b05f67b7c9d12f8f0f4a59fa004146c0 267 Pfam PF04542 Sigma-70 region 2 98 160 8.7E-10 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 Astex_2234 b05f67b7c9d12f8f0f4a59fa004146c0 267 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 98 241 1.6E-15 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 Astex_2234 b05f67b7c9d12f8f0f4a59fa004146c0 267 SUPERFAMILY SSF47413 14 80 1.96E-12 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Astex_2234 b05f67b7c9d12f8f0f4a59fa004146c0 267 SUPERFAMILY SSF88946 92 175 4.71E-11 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 Astex_2234 b05f67b7c9d12f8f0f4a59fa004146c0 267 Gene3D G3DSA:1.10.10.10 169 253 5.0E-11 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_2234 b05f67b7c9d12f8f0f4a59fa004146c0 267 SMART SM00530 19 74 2.9E-9 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Astex_2234 b05f67b7c9d12f8f0f4a59fa004146c0 267 Gene3D G3DSA:1.10.1740.10 89 161 2.4E-9 T 13-10-2018 Astex_0801 54b9b48b695c48a0e28abd17093da82a 150 Pfam PF14539 Domain of unknown function (DUF4442) 12 144 3.6E-25 T 13-10-2018 IPR027961 Protein of unknown function DUF4442 Astex_0801 54b9b48b695c48a0e28abd17093da82a 150 Gene3D G3DSA:3.10.129.10 15 149 1.5E-31 T 13-10-2018 Astex_0801 54b9b48b695c48a0e28abd17093da82a 150 SUPERFAMILY SSF54637 11 149 8.67E-24 T 13-10-2018 IPR029069 HotDog domain superfamily Astex_0510 b3cc9b847cbe1c50af9228c8122a24a0 132 Gene3D G3DSA:2.60.40.1470 2 131 8.8E-42 T 13-10-2018 IPR036767 ApaG domain superfamily Astex_0510 b3cc9b847cbe1c50af9228c8122a24a0 132 SUPERFAMILY SSF110069 6 128 5.62E-42 T 13-10-2018 IPR036767 ApaG domain superfamily Astex_0510 b3cc9b847cbe1c50af9228c8122a24a0 132 Pfam PF04379 ApaG domain 27 106 2.8E-29 T 13-10-2018 IPR007474 ApaG domain Astex_2867 d85bd4c139d147a8bca2879ab914960b 448 Hamap MF_00900 GTPase HflX [hflX]. 48 417 47.198 T 13-10-2018 IPR016496 GTPase HflX GO:0005525 Astex_2867 d85bd4c139d147a8bca2879ab914960b 448 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 43 385 1.0E-133 T 13-10-2018 IPR016496 GTPase HflX GO:0005525 Astex_2867 d85bd4c139d147a8bca2879ab914960b 448 SUPERFAMILY SSF52540 219 387 4.67E-39 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2867 d85bd4c139d147a8bca2879ab914960b 448 Gene3D G3DSA:3.40.50.300 218 394 3.1E-39 T 13-10-2018 Astex_2867 d85bd4c139d147a8bca2879ab914960b 448 Gene3D G3DSA:3.40.50.11060 38 159 2.2E-38 T 13-10-2018 Astex_2867 d85bd4c139d147a8bca2879ab914960b 448 Pfam PF13167 GTP-binding GTPase N-terminal 46 132 2.8E-28 T 13-10-2018 IPR025121 GTPase HflX, N-terminal Astex_2867 d85bd4c139d147a8bca2879ab914960b 448 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 221 241 8.1E-7 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Astex_2867 d85bd4c139d147a8bca2879ab914960b 448 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 288 306 8.1E-7 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Astex_2867 d85bd4c139d147a8bca2879ab914960b 448 PIRSF PIRSF006809 27 446 1.2E-139 T 13-10-2018 IPR016496 GTPase HflX GO:0005525 Astex_2867 d85bd4c139d147a8bca2879ab914960b 448 Pfam PF01926 50S ribosome-binding GTPase 221 341 3.1E-18 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Astex_2867 d85bd4c139d147a8bca2879ab914960b 448 Pfam PF16360 GTP-binding GTPase Middle Region 135 213 2.5E-28 T 13-10-2018 IPR032305 GTP-binding protein, middle domain Astex_1989 69660e04400e43acab8a56caa0e40ae4 235 SMART SM00448 6 116 1.3E-37 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1989 69660e04400e43acab8a56caa0e40ae4 235 SMART SM00862 151 227 1.2E-16 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Astex_1989 69660e04400e43acab8a56caa0e40ae4 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 227 8.9E-19 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Astex_1989 69660e04400e43acab8a56caa0e40ae4 235 Pfam PF00072 Response regulator receiver domain 8 117 2.8E-28 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1989 69660e04400e43acab8a56caa0e40ae4 235 Gene3D G3DSA:3.40.50.2300 2 126 4.7E-36 T 13-10-2018 Astex_1989 69660e04400e43acab8a56caa0e40ae4 235 Gene3D G3DSA:1.10.10.10 127 228 6.2E-27 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1989 69660e04400e43acab8a56caa0e40ae4 235 SUPERFAMILY SSF52172 5 188 4.13E-40 T 13-10-2018 IPR011006 CheY-like superfamily Astex_3047 c1d95b2652ed587a69b31ab6934a53c3 180 Gene3D G3DSA:3.40.630.30 1 170 9.8E-54 T 13-10-2018 Astex_3047 c1d95b2652ed587a69b31ab6934a53c3 180 SUPERFAMILY SSF55729 4 166 1.86E-32 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Astex_3047 c1d95b2652ed587a69b31ab6934a53c3 180 Pfam PF13420 Acetyltransferase (GNAT) domain 4 157 7.3E-22 T 13-10-2018 Astex_2162 fe26296c8fd4069432f267e28e02120f 208 SUPERFAMILY SSF47413 146 203 6.44E-12 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Astex_2162 fe26296c8fd4069432f267e28e02120f 208 Pfam PF01381 Helix-turn-helix 153 200 2.4E-8 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Astex_2162 fe26296c8fd4069432f267e28e02120f 208 SMART SM00530 151 206 3.2E-6 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Astex_2162 fe26296c8fd4069432f267e28e02120f 208 Gene3D G3DSA:1.10.260.40 139 208 8.8E-15 T 13-10-2018 Astex_2162 fe26296c8fd4069432f267e28e02120f 208 TIGRFAM TIGR03070 couple_hipB: transcriptional regulator, y4mF family 146 203 4.4E-23 T 13-10-2018 IPR017507 Transcription regulator, HipB-like Astex_0134 89edac016bcb96c75490bbaa4bef8f85 855 Gene3D G3DSA:3.40.50.620 35 573 0.0 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Astex_0134 89edac016bcb96c75490bbaa4bef8f85 855 Gene3D G3DSA:3.10.330.110 574 630 0.0 T 13-10-2018 Astex_0134 89edac016bcb96c75490bbaa4bef8f85 855 SUPERFAMILY SSF52374 3 669 4.43E-144 T 13-10-2018 Astex_0134 89edac016bcb96c75490bbaa4bef8f85 855 Pfam PF09334 tRNA synthetases class I (M) 39 173 6.3E-18 T 13-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 Astex_0134 89edac016bcb96c75490bbaa4bef8f85 855 SUPERFAMILY SSF50677 228 416 1.57E-42 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Astex_0134 89edac016bcb96c75490bbaa4bef8f85 855 Gene3D G3DSA:3.90.740.10 229 420 0.0 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Astex_0134 89edac016bcb96c75490bbaa4bef8f85 855 Gene3D G3DSA:3.10.20.590 795 855 4.1E-23 T 13-10-2018 Astex_0134 89edac016bcb96c75490bbaa4bef8f85 855 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 44 55 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Astex_0134 89edac016bcb96c75490bbaa4bef8f85 855 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 4 854 2.4E-298 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 Astex_0134 89edac016bcb96c75490bbaa4bef8f85 855 Gene3D G3DSA:1.10.730.10 7 786 0.0 T 13-10-2018 Astex_0134 89edac016bcb96c75490bbaa4bef8f85 855 Pfam PF08264 Anticodon-binding domain of tRNA 700 816 1.9E-16 T 13-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 Astex_0134 89edac016bcb96c75490bbaa4bef8f85 855 SUPERFAMILY SSF47323 664 854 1.12E-34 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Astex_0134 89edac016bcb96c75490bbaa4bef8f85 855 PRINTS PR00985 Leucyl-tRNA synthetase signature 217 236 1.7E-44 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 Astex_0134 89edac016bcb96c75490bbaa4bef8f85 855 PRINTS PR00985 Leucyl-tRNA synthetase signature 155 171 1.7E-44 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 Astex_0134 89edac016bcb96c75490bbaa4bef8f85 855 PRINTS PR00985 Leucyl-tRNA synthetase signature 564 574 1.7E-44 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 Astex_0134 89edac016bcb96c75490bbaa4bef8f85 855 PRINTS PR00985 Leucyl-tRNA synthetase signature 187 200 1.7E-44 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 Astex_0134 89edac016bcb96c75490bbaa4bef8f85 855 PRINTS PR00985 Leucyl-tRNA synthetase signature 129 146 1.7E-44 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 Astex_0134 89edac016bcb96c75490bbaa4bef8f85 855 PRINTS PR00985 Leucyl-tRNA synthetase signature 493 511 1.7E-44 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 Astex_0134 89edac016bcb96c75490bbaa4bef8f85 855 PRINTS PR00985 Leucyl-tRNA synthetase signature 531 553 1.7E-44 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 Astex_0134 89edac016bcb96c75490bbaa4bef8f85 855 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 620 660 2.7E-8 T 13-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Astex_0134 89edac016bcb96c75490bbaa4bef8f85 855 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 423 579 3.6E-7 T 13-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Astex_0134 89edac016bcb96c75490bbaa4bef8f85 855 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 3 854 22.301 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 Astex_0134 89edac016bcb96c75490bbaa4bef8f85 855 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 224 409 1.6E-64 T 13-10-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 Astex_0160 be418a4d06e9339b38b87dd3911091b8 154 Pfam PF00582 Universal stress protein family 1 115 4.7E-12 T 13-10-2018 IPR006016 UspA Astex_0160 be418a4d06e9339b38b87dd3911091b8 154 SUPERFAMILY SSF52402 1 143 4.6E-14 T 13-10-2018 Astex_0160 be418a4d06e9339b38b87dd3911091b8 154 Gene3D G3DSA:3.40.50.620 1 142 1.3E-13 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Astex_0138 1995cca9267414112adabbf475ab62b9 273 Pfam PF13614 AAA domain 12 190 4.6E-58 T 13-10-2018 IPR025669 AAA domain Astex_0138 1995cca9267414112adabbf475ab62b9 273 Gene3D G3DSA:3.40.50.300 8 272 8.1E-78 T 13-10-2018 Astex_0138 1995cca9267414112adabbf475ab62b9 273 SUPERFAMILY SSF52540 10 267 4.1E-66 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0691 80389a005d7b06abed264ef4092c2922 357 Gene3D G3DSA:3.30.66.10 24 108 9.4E-32 T 13-10-2018 IPR035447 DNA topoisomerase I, N-terminal Astex_0691 80389a005d7b06abed264ef4092c2922 357 SUPERFAMILY SSF56349 98 321 2.0E-66 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 Astex_0691 80389a005d7b06abed264ef4092c2922 357 SUPERFAMILY SSF55869 42 103 3.66E-22 T 13-10-2018 IPR035447 DNA topoisomerase I, N-terminal Astex_0691 80389a005d7b06abed264ef4092c2922 357 Pfam PF01028 Eukaryotic DNA topoisomerase I, catalytic core 102 313 6.9E-34 T 13-10-2018 IPR013500 DNA topoisomerase I, catalytic core, eukaryotic-type GO:0003677|GO:0003917|GO:0006265 Astex_0691 80389a005d7b06abed264ef4092c2922 357 Gene3D G3DSA:1.10.132.120 110 347 4.8E-88 T 13-10-2018 Astex_0691 80389a005d7b06abed264ef4092c2922 357 Gene3D G3DSA:3.90.15.10 133 252 4.8E-88 T 13-10-2018 IPR014711 DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type GO:0003677|GO:0003917|GO:0006265 Astex_0691 80389a005d7b06abed264ef4092c2922 357 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 165 179 1.5E-9 T 13-10-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 Astex_0691 80389a005d7b06abed264ef4092c2922 357 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 302 313 1.5E-9 T 13-10-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 Astex_0691 80389a005d7b06abed264ef4092c2922 357 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 186 202 1.5E-9 T 13-10-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 Astex_0691 80389a005d7b06abed264ef4092c2922 357 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 142 161 1.5E-9 T 13-10-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 Astex_0691 80389a005d7b06abed264ef4092c2922 357 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 251 265 1.5E-9 T 13-10-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 Astex_1015 b45515650302193e3fcbb8e5be8fc2cd 466 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 264 279 - T 13-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 Astex_1015 b45515650302193e3fcbb8e5be8fc2cd 466 Gene3D G3DSA:3.10.20.70 18 130 2.2E-8 T 13-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Astex_1015 b45515650302193e3fcbb8e5be8fc2cd 466 SUPERFAMILY SSF54368 21 127 7.06E-20 T 13-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Astex_1015 b45515650302193e3fcbb8e5be8fc2cd 466 Gene3D G3DSA:3.30.590.10 131 464 7.0E-101 T 13-10-2018 Astex_1015 b45515650302193e3fcbb8e5be8fc2cd 466 Pfam PF00120 Glutamine synthetase, catalytic domain 129 460 7.3E-107 T 13-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Astex_1015 b45515650302193e3fcbb8e5be8fc2cd 466 SMART SM01230 128 384 2.1E-110 T 13-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 Astex_1015 b45515650302193e3fcbb8e5be8fc2cd 466 SUPERFAMILY SSF55931 130 463 1.37E-106 T 13-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Astex_3401 4c1c68b83234c525e2bf4e81fb6f7d9c 341 Gene3D G3DSA:3.40.50.2300 58 309 1.8E-61 T 13-10-2018 Astex_3401 4c1c68b83234c525e2bf4e81fb6f7d9c 341 ProSitePatterns PS00356 LacI-type HTH domain signature. 6 24 - T 13-10-2018 Astex_3401 4c1c68b83234c525e2bf4e81fb6f7d9c 341 Gene3D G3DSA:1.10.260.40 1 57 4.6E-20 T 13-10-2018 Astex_3401 4c1c68b83234c525e2bf4e81fb6f7d9c 341 SUPERFAMILY SSF47413 2 61 1.55E-15 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Astex_3401 4c1c68b83234c525e2bf4e81fb6f7d9c 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 50 3.1E-15 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Astex_3401 4c1c68b83234c525e2bf4e81fb6f7d9c 341 SUPERFAMILY SSF53822 67 339 4.91E-60 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Astex_3401 4c1c68b83234c525e2bf4e81fb6f7d9c 341 Gene3D G3DSA:3.40.50.2300 165 293 1.8E-61 T 13-10-2018 Astex_3401 4c1c68b83234c525e2bf4e81fb6f7d9c 341 SMART SM00354 3 73 2.0E-22 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Astex_3401 4c1c68b83234c525e2bf4e81fb6f7d9c 341 Pfam PF13377 Periplasmic binding protein-like domain 174 335 1.2E-31 T 13-10-2018 Astex_2894 970fb5ee7bef9596f1a07476328726a1 127 Gene3D G3DSA:3.30.1330.40 1 126 8.2E-31 T 13-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 Astex_2894 970fb5ee7bef9596f1a07476328726a1 127 SUPERFAMILY SSF55298 1 125 9.42E-32 T 13-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 Astex_2894 970fb5ee7bef9596f1a07476328726a1 127 Pfam PF01042 Endoribonuclease L-PSP 12 124 3.3E-23 T 13-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 Astex_1138 237e68c628c4d9151fafacd048649ddd 236 SUPERFAMILY SSF52317 22 191 2.75E-32 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Astex_1138 237e68c628c4d9151fafacd048649ddd 236 Pfam PF00117 Glutamine amidotransferase class-I 53 190 7.4E-15 T 13-10-2018 IPR017926 Glutamine amidotransferase Astex_1138 237e68c628c4d9151fafacd048649ddd 236 Gene3D G3DSA:3.40.50.880 15 232 6.9E-38 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Astex_3217 b1b7aac88132cf1bec3f492a356ee034 525 ProSitePatterns PS01027 Glycosyl hydrolases family 39 active site. 178 187 - T 13-10-2018 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101|Reactome: R-HSA-2206302 Astex_3217 b1b7aac88132cf1bec3f492a356ee034 525 Gene3D G3DSA:3.20.20.80 67 383 1.3E-158 T 13-10-2018 Astex_3217 b1b7aac88132cf1bec3f492a356ee034 525 Gene3D G3DSA:2.60.40.1500 384 519 1.3E-158 T 13-10-2018 Astex_3217 b1b7aac88132cf1bec3f492a356ee034 525 SUPERFAMILY SSF51445 48 383 6.34E-74 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_3217 b1b7aac88132cf1bec3f492a356ee034 525 SUPERFAMILY SSF51011 372 524 1.15E-21 T 13-10-2018 Astex_3217 b1b7aac88132cf1bec3f492a356ee034 525 PRINTS PR00745 Glycosyl hydrolase family 39 signature 175 191 6.7E-15 T 13-10-2018 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101|Reactome: R-HSA-2206302 Astex_3217 b1b7aac88132cf1bec3f492a356ee034 525 PRINTS PR00745 Glycosyl hydrolase family 39 signature 158 175 6.7E-15 T 13-10-2018 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101|Reactome: R-HSA-2206302 Astex_3217 b1b7aac88132cf1bec3f492a356ee034 525 PRINTS PR00745 Glycosyl hydrolase family 39 signature 112 128 6.7E-15 T 13-10-2018 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101|Reactome: R-HSA-2206302 Astex_3217 b1b7aac88132cf1bec3f492a356ee034 525 PRINTS PR00745 Glycosyl hydrolase family 39 signature 237 251 6.7E-15 T 13-10-2018 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101|Reactome: R-HSA-2206302 Astex_3217 b1b7aac88132cf1bec3f492a356ee034 525 Pfam PF01229 Glycosyl hydrolases family 39 33 522 6.0E-91 T 13-10-2018 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101|Reactome: R-HSA-2206302 Astex_1367 0a717a98f9b640c690770fd63ef1d5d2 409 ProSitePatterns PS00216 Sugar transport proteins signature 1. 71 87 - T 13-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Astex_1367 0a717a98f9b640c690770fd63ef1d5d2 409 SUPERFAMILY SSF103473 13 395 4.05E-52 T 13-10-2018 IPR036259 MFS transporter superfamily Astex_1367 0a717a98f9b640c690770fd63ef1d5d2 409 Gene3D G3DSA:1.20.1250.20 14 202 2.8E-32 T 13-10-2018 Astex_1367 0a717a98f9b640c690770fd63ef1d5d2 409 Pfam PF07690 Major Facilitator Superfamily 22 358 3.4E-35 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Astex_1367 0a717a98f9b640c690770fd63ef1d5d2 409 Gene3D G3DSA:1.20.1250.20 207 396 1.6E-29 T 13-10-2018 Astex_2651 451ea720f0c6fb7d871e59a74ef9f365 354 SUPERFAMILY SSF56300 30 276 1.52E-12 T 13-10-2018 Astex_0759 dca12a72baa4daf140066c56094cfddd 255 Pfam PF00899 ThiF family 18 247 4.7E-58 T 13-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 Astex_0759 dca12a72baa4daf140066c56094cfddd 255 SUPERFAMILY SSF69572 9 251 2.49E-82 T 13-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 Astex_0759 dca12a72baa4daf140066c56094cfddd 255 Gene3D G3DSA:3.40.50.720 10 254 6.7E-85 T 13-10-2018 Astex_1875 23cc740691ef9f937cbceb93c0b222e0 149 Pfam PF00293 NUDIX domain 14 140 3.8E-10 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 Astex_1875 23cc740691ef9f937cbceb93c0b222e0 149 Gene3D G3DSA:3.90.79.10 10 146 6.9E-24 T 13-10-2018 Astex_1875 23cc740691ef9f937cbceb93c0b222e0 149 SUPERFAMILY SSF55811 7 145 3.11E-19 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 Astex_1710 73b0ba65e8c324950ff01af77a4d07cb 323 SMART SM00829 11 321 1.4E-43 T 13-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Astex_1710 73b0ba65e8c324950ff01af77a4d07cb 323 SUPERFAMILY SSF50129 1 141 6.24E-36 T 13-10-2018 IPR011032 GroES-like superfamily Astex_1710 73b0ba65e8c324950ff01af77a4d07cb 323 Pfam PF00107 Zinc-binding dehydrogenase 152 264 6.4E-28 T 13-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Astex_1710 73b0ba65e8c324950ff01af77a4d07cb 323 Gene3D G3DSA:3.90.180.10 14 321 6.9E-98 T 13-10-2018 Astex_1710 73b0ba65e8c324950ff01af77a4d07cb 323 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 1 322 3.2E-122 T 13-10-2018 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 Astex_1710 73b0ba65e8c324950ff01af77a4d07cb 323 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 88 2.6E-7 T 13-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Astex_1710 73b0ba65e8c324950ff01af77a4d07cb 323 SUPERFAMILY SSF51735 112 285 6.47E-44 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_1710 73b0ba65e8c324950ff01af77a4d07cb 323 Gene3D G3DSA:3.40.50.720 121 260 6.9E-98 T 13-10-2018 Astex_2995 f7ef0bdbdbddaff4834b32fa3ff1cd54 410 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 185 393 1.5E-45 T 13-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 Astex_2995 f7ef0bdbdbddaff4834b32fa3ff1cd54 410 SMART SM00646 244 393 1.2E-32 T 13-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 Astex_2995 f7ef0bdbdbddaff4834b32fa3ff1cd54 410 Gene3D G3DSA:3.40.630.40 172 405 3.9E-65 T 13-10-2018 Astex_2995 f7ef0bdbdbddaff4834b32fa3ff1cd54 410 SUPERFAMILY SSF53187 183 396 1.41E-48 T 13-10-2018 Astex_0248 068d810915510380d82178725639bae5 219 Pfam PF13860 FlgD Ig-like domain 101 175 7.3E-15 T 13-10-2018 IPR025965 FlgD Ig-like domain Astex_0248 068d810915510380d82178725639bae5 219 Gene3D G3DSA:2.30.30.910 88 214 7.5E-20 T 13-10-2018 Astex_0248 068d810915510380d82178725639bae5 219 Pfam PF03963 Flagellar hook capping protein - N-terminal region 5 74 3.0E-22 T 13-10-2018 IPR005648 Flagellar hook capping protein Astex_0248 068d810915510380d82178725639bae5 219 Gene3D G3DSA:2.60.40.4070 99 185 7.5E-20 T 13-10-2018 Astex_0248 068d810915510380d82178725639bae5 219 Pfam PF13861 FlgD Tudor-like domain 85 215 3.6E-8 T 13-10-2018 IPR025963 FlgD Tudor-like domain Astex_1622 9c416e710b80f4f76245222ca14dee40 425 Pfam PF11799 impB/mucB/samB family C-terminal domain 252 359 4.2E-8 T 13-10-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 Astex_1622 9c416e710b80f4f76245222ca14dee40 425 SUPERFAMILY SSF56672 17 250 2.76E-53 T 13-10-2018 Astex_1622 9c416e710b80f4f76245222ca14dee40 425 Gene3D G3DSA:1.10.150.20 191 245 4.5E-7 T 13-10-2018 Astex_1622 9c416e710b80f4f76245222ca14dee40 425 Gene3D G3DSA:3.30.70.270 18 176 5.4E-39 T 13-10-2018 Astex_1622 9c416e710b80f4f76245222ca14dee40 425 Pfam PF00817 impB/mucB/samB family 20 168 1.1E-31 T 13-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 Astex_1622 9c416e710b80f4f76245222ca14dee40 425 Gene3D G3DSA:2.30.40.20 25 88 5.4E-39 T 13-10-2018 Astex_2272 c85c71f811d30cc679fe3af019064747 366 Gene3D G3DSA:3.50.50.60 1 80 4.3E-7 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_2272 c85c71f811d30cc679fe3af019064747 366 Pfam PF01266 FAD dependent oxidoreductase 4 59 1.3E-6 T 13-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 Astex_2272 c85c71f811d30cc679fe3af019064747 366 SUPERFAMILY SSF51905 3 212 4.48E-13 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_3603 f470de65ae8ba5fd570f24b2a608e1c1 850 Gene3D G3DSA:3.30.2080.10 304 721 7.6E-157 T 13-10-2018 Astex_3603 f470de65ae8ba5fd570f24b2a608e1c1 850 Gene3D G3DSA:1.20.1610.10 447 597 7.6E-157 T 13-10-2018 Astex_3603 f470de65ae8ba5fd570f24b2a608e1c1 850 SUPERFAMILY SSF48208 269 702 8.67E-15 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 Astex_3603 f470de65ae8ba5fd570f24b2a608e1c1 850 Gene3D G3DSA:2.70.98.10 35 348 7.6E-157 T 13-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 Astex_3603 f470de65ae8ba5fd570f24b2a608e1c1 850 Pfam PF07971 Glycosyl hydrolase family 92 245 717 1.4E-120 T 13-10-2018 IPR012939 Glycosyl hydrolase family 92 Astex_3603 f470de65ae8ba5fd570f24b2a608e1c1 850 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 37 721 1.5E-88 T 13-10-2018 IPR005887 Alpha-1,2-mannosidase, putative Astex_3603 f470de65ae8ba5fd570f24b2a608e1c1 850 Gene3D G3DSA:1.20.1050.60 349 446 7.6E-157 T 13-10-2018 Astex_2531 4f48d9d5bf26e67253cf703cbad9a7c6 477 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 194 355 8.0E-44 T 13-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 Astex_2531 4f48d9d5bf26e67253cf703cbad9a7c6 477 Gene3D G3DSA:3.30.465.10 244 355 3.4E-33 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 Astex_2531 4f48d9d5bf26e67253cf703cbad9a7c6 477 SUPERFAMILY SSF56176 193 355 4.09E-47 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 Astex_2531 4f48d9d5bf26e67253cf703cbad9a7c6 477 Gene3D G3DSA:3.30.390.50 363 466 2.9E-26 T 13-10-2018 Astex_2531 4f48d9d5bf26e67253cf703cbad9a7c6 477 TIGRFAM TIGR02963 xanthine_xdhA: xanthine dehydrogenase, small subunit 5 463 3.3E-175 T 13-10-2018 IPR014307 Xanthine dehydrogenase, small subunit GO:0004854|GO:0004855|GO:0050660|GO:0055114 KEGG: 00230+1.17.1.4|MetaCyc: PWY-5497|MetaCyc: PWY-5695|MetaCyc: PWY-6538|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-6999|Reactome: R-HSA-74259|Reactome: R-HSA-8851680 Astex_2531 4f48d9d5bf26e67253cf703cbad9a7c6 477 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 8 71 6.3E-5 T 13-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 Astex_2531 4f48d9d5bf26e67253cf703cbad9a7c6 477 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 42 50 - T 13-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 Astex_2531 4f48d9d5bf26e67253cf703cbad9a7c6 477 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 366 463 4.8E-28 T 13-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal Astex_2531 4f48d9d5bf26e67253cf703cbad9a7c6 477 Gene3D G3DSA:3.10.20.30 1 87 1.4E-25 T 13-10-2018 IPR012675 Beta-grasp domain superfamily Astex_2531 4f48d9d5bf26e67253cf703cbad9a7c6 477 PIRSF PIRSF036557 2 475 5.5E-179 T 13-10-2018 IPR012175 Xanthine dehydrogenase, small subunit, bacteria Astex_2531 4f48d9d5bf26e67253cf703cbad9a7c6 477 SUPERFAMILY SSF54292 5 89 2.22E-16 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 Astex_2531 4f48d9d5bf26e67253cf703cbad9a7c6 477 Pfam PF01799 [2Fe-2S] binding domain 84 153 6.3E-23 T 13-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 Astex_2531 4f48d9d5bf26e67253cf703cbad9a7c6 477 SMART SM01092 363 464 8.7E-31 T 13-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal Astex_2531 4f48d9d5bf26e67253cf703cbad9a7c6 477 SUPERFAMILY SSF55447 361 467 1.15E-32 T 13-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily Astex_2531 4f48d9d5bf26e67253cf703cbad9a7c6 477 Gene3D G3DSA:3.30.43.10 195 243 8.8E-19 T 13-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 Astex_2531 4f48d9d5bf26e67253cf703cbad9a7c6 477 SUPERFAMILY SSF47741 84 165 4.45E-27 T 13-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily Astex_2531 4f48d9d5bf26e67253cf703cbad9a7c6 477 Gene3D G3DSA:1.10.150.120 88 171 1.8E-25 T 13-10-2018 Astex_3432 fe9d25a91573441c47acd4458040567c 377 Pfam PF07859 alpha/beta hydrolase fold 148 352 3.0E-59 T 13-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 Astex_3432 fe9d25a91573441c47acd4458040567c 377 Gene3D G3DSA:3.40.50.1820 49 375 1.4E-77 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_3432 fe9d25a91573441c47acd4458040567c 377 SUPERFAMILY SSF53474 92 368 2.1E-63 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_3432 fe9d25a91573441c47acd4458040567c 377 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 213 228 - T 13-10-2018 IPR019826 Carboxylesterase type B, active site Astex_2216 9cbd6c4b341ef776794bfed460962a7b 390 Pfam PF00534 Glycosyl transferases group 1 189 332 2.0E-26 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 Astex_2216 9cbd6c4b341ef776794bfed460962a7b 390 Gene3D G3DSA:3.40.50.2000 1 195 1.2E-5 T 13-10-2018 Astex_2216 9cbd6c4b341ef776794bfed460962a7b 390 SUPERFAMILY SSF53756 1 360 2.06E-56 T 13-10-2018 Astex_2216 9cbd6c4b341ef776794bfed460962a7b 390 Gene3D G3DSA:3.40.50.2000 196 346 2.2E-27 T 13-10-2018 Astex_3090 c9fa33289ecc6315ac4c8f4a97860156 641 SUPERFAMILY SSF69304 92 335 1.83E-26 T 13-10-2018 Astex_3090 c9fa33289ecc6315ac4c8f4a97860156 641 Pfam PF00326 Prolyl oligopeptidase family 432 638 3.0E-28 T 13-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 Astex_3090 c9fa33289ecc6315ac4c8f4a97860156 641 Gene3D G3DSA:2.120.10.30 54 258 1.9E-17 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like Astex_3090 c9fa33289ecc6315ac4c8f4a97860156 641 Gene3D G3DSA:3.40.50.1820 348 639 6.5E-56 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_3090 c9fa33289ecc6315ac4c8f4a97860156 641 SUPERFAMILY SSF53474 380 638 1.37E-46 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_2378 e6b40b5a995b172c1a533c4752e1e40d 666 SUPERFAMILY SSF53955 55 271 2.47E-70 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily Astex_2378 e6b40b5a995b172c1a533c4752e1e40d 666 Pfam PF00905 Penicillin binding protein transpeptidase domain 334 592 1.8E-32 T 13-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 Astex_2378 e6b40b5a995b172c1a533c4752e1e40d 666 SUPERFAMILY SSF56601 221 645 1.48E-115 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like Astex_2378 e6b40b5a995b172c1a533c4752e1e40d 666 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 76 596 2.3E-185 T 13-10-2018 Astex_2378 e6b40b5a995b172c1a533c4752e1e40d 666 Gene3D G3DSA:3.40.710.10 257 645 2.1E-109 T 13-10-2018 Astex_2378 e6b40b5a995b172c1a533c4752e1e40d 666 Pfam PF00912 Transglycosylase 74 239 1.1E-58 T 13-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Astex_2378 e6b40b5a995b172c1a533c4752e1e40d 666 Gene3D G3DSA:1.10.3810.10 56 255 2.6E-70 T 13-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Astex_0521 5bb83da1ee079430067fa356ba7b9923 307 SUPERFAMILY SSF53671 2 306 3.67E-106 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 Astex_0521 5bb83da1ee079430067fa356ba7b9923 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 223 233 3.4E-28 T 13-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 Astex_0521 5bb83da1ee079430067fa356ba7b9923 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 124 138 3.4E-28 T 13-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 Astex_0521 5bb83da1ee079430067fa356ba7b9923 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 284 295 3.4E-28 T 13-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 Astex_0521 5bb83da1ee079430067fa356ba7b9923 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 51 65 3.4E-28 T 13-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 Astex_0521 5bb83da1ee079430067fa356ba7b9923 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 84 97 3.4E-28 T 13-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 Astex_0521 5bb83da1ee079430067fa356ba7b9923 307 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 154 303 7.0E-52 T 13-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 Astex_0521 5bb83da1ee079430067fa356ba7b9923 307 Gene3D G3DSA:3.40.50.1370 11 301 3.4E-116 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 Astex_0521 5bb83da1ee079430067fa356ba7b9923 307 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 53 60 - T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Astex_0521 5bb83da1ee079430067fa356ba7b9923 307 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 2 306 78.83 T 13-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 Astex_0521 5bb83da1ee079430067fa356ba7b9923 307 Gene3D G3DSA:3.40.50.1370 138 292 3.4E-116 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 Astex_0521 5bb83da1ee079430067fa356ba7b9923 307 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 3 148 1.1E-48 T 13-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 Astex_0521 5bb83da1ee079430067fa356ba7b9923 307 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 3 305 8.0E-115 T 13-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 Astex_0521 5bb83da1ee079430067fa356ba7b9923 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 53 72 2.6E-26 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Astex_0521 5bb83da1ee079430067fa356ba7b9923 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 2.6E-26 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Astex_0521 5bb83da1ee079430067fa356ba7b9923 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 270 293 2.6E-26 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Astex_0521 5bb83da1ee079430067fa356ba7b9923 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 258 267 2.6E-26 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Astex_0066 e4a96d5a955c2a4157f8da70e71f9236 508 TIGRFAM TIGR01982 UbiB: 2-polyprenylphenol 6-hydroxylase 8 442 3.7E-157 T 13-10-2018 IPR010232 Probable protein kinase UbiB GO:0006744 Astex_0066 e4a96d5a955c2a4157f8da70e71f9236 508 SUPERFAMILY SSF56112 98 434 4.38E-36 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily Astex_0066 e4a96d5a955c2a4157f8da70e71f9236 508 Pfam PF03109 ABC1 family 116 232 4.5E-27 T 13-10-2018 IPR004147 UbiB domain Astex_3553 b6029e47ea572ba5e72aa484a6e77d46 403 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 313 368 2.2E-5 T 13-10-2018 IPR037682 TonB, C-terminal GO:0055085 Astex_3553 b6029e47ea572ba5e72aa484a6e77d46 403 SUPERFAMILY SSF74653 307 366 3.14E-6 T 13-10-2018 Astex_3553 b6029e47ea572ba5e72aa484a6e77d46 403 Gene3D G3DSA:3.30.2420.10 305 388 8.8E-6 T 13-10-2018 Astex_0711 15b1b36fbdcdbcfed3e9a489b1d5772a 527 Pfam PF00682 HMGL-like 12 278 1.6E-88 T 13-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 Astex_0711 15b1b36fbdcdbcfed3e9a489b1d5772a 527 Gene3D G3DSA:1.10.238.260 288 404 1.5E-33 T 13-10-2018 Astex_0711 15b1b36fbdcdbcfed3e9a489b1d5772a 527 SUPERFAMILY SSF110921 417 500 1.23E-5 T 13-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Astex_0711 15b1b36fbdcdbcfed3e9a489b1d5772a 527 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 19 35 - T 13-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Astex_0711 15b1b36fbdcdbcfed3e9a489b1d5772a 527 Gene3D G3DSA:3.20.20.70 8 283 1.4E-101 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_0711 15b1b36fbdcdbcfed3e9a489b1d5772a 527 SUPERFAMILY SSF51569 8 298 1.27E-91 T 13-10-2018 Astex_0711 15b1b36fbdcdbcfed3e9a489b1d5772a 527 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 206 219 - T 13-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 Astex_2510 5fc1401fdb68de4f426386825368651d 404 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 393 1.7E-75 T 13-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 Astex_2510 5fc1401fdb68de4f426386825368651d 404 SMART SM01329 9 394 9.2E-134 T 13-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 Astex_2510 5fc1401fdb68de4f426386825368651d 404 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 269 288 - T 13-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 Astex_2510 5fc1401fdb68de4f426386825368651d 404 PIRSF PIRSF000108 1 404 5.9E-225 T 13-10-2018 IPR004790 Isocitrate dehydrogenase NADP-dependent GO:0004450|GO:0006102|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 Astex_2510 5fc1401fdb68de4f426386825368651d 404 Gene3D G3DSA:3.40.718.10 1 404 1.6E-218 T 13-10-2018 Astex_2510 5fc1401fdb68de4f426386825368651d 404 SUPERFAMILY SSF53659 1 402 8.28E-153 T 13-10-2018 Astex_2510 5fc1401fdb68de4f426386825368651d 404 TIGRFAM TIGR00127 nadp_idh_euk: isocitrate dehydrogenase, NADP-dependent 3 403 5.7E-210 T 13-10-2018 IPR004790 Isocitrate dehydrogenase NADP-dependent GO:0004450|GO:0006102|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 Astex_2832 4e8798210b8f4bbebba587e7b3c3dbd8 349 Hamap MF_01665 Heme A synthase [ctaA]. 7 340 23.346 T 13-10-2018 IPR023754 Heme A synthase, type 2 GO:0006784|GO:0016020|GO:0016627|GO:0055114 Reactome: R-HSA-189451 Astex_2832 4e8798210b8f4bbebba587e7b3c3dbd8 349 Pfam PF02628 Cytochrome oxidase assembly protein 12 330 2.7E-102 T 13-10-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 Astex_2588 261394d4a1419ce3cf1aea3fbce9980a 771 Pfam PF00326 Prolyl oligopeptidase family 575 767 7.6E-39 T 13-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 Astex_2588 261394d4a1419ce3cf1aea3fbce9980a 771 Gene3D G3DSA:2.140.10.30 94 502 1.1E-60 T 13-10-2018 IPR038554 Dipeptidylpeptidase IV, N-terminal domain superfamily Astex_2588 261394d4a1419ce3cf1aea3fbce9980a 771 Pfam PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region 153 488 8.7E-37 T 13-10-2018 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 Astex_2588 261394d4a1419ce3cf1aea3fbce9980a 771 SUPERFAMILY SSF82171 154 501 1.26E-23 T 13-10-2018 Astex_2588 261394d4a1419ce3cf1aea3fbce9980a 771 Gene3D G3DSA:3.40.50.1820 517 766 2.0E-53 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_2588 261394d4a1419ce3cf1aea3fbce9980a 771 SUPERFAMILY SSF53474 520 767 2.08E-52 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1506 1c8e8cef8c699cc7c4a821e2ecf51f2e 333 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 19 140 1.4E-22 T 13-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 Astex_1506 1c8e8cef8c699cc7c4a821e2ecf51f2e 333 SUPERFAMILY SSF55347 172 275 6.1E-6 T 13-10-2018 Astex_1506 1c8e8cef8c699cc7c4a821e2ecf51f2e 333 Gene3D G3DSA:3.30.360.10 152 333 2.0E-13 T 13-10-2018 Astex_1506 1c8e8cef8c699cc7c4a821e2ecf51f2e 333 SUPERFAMILY SSF51735 18 153 2.63E-31 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_1506 1c8e8cef8c699cc7c4a821e2ecf51f2e 333 Gene3D G3DSA:3.40.50.720 16 151 3.3E-30 T 13-10-2018 Astex_3472 b219e45b47a142ac019a8d62a7cd383b 189 SUPERFAMILY SSF48150 6 187 5.1E-78 T 13-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 Astex_3472 b219e45b47a142ac019a8d62a7cd383b 189 Gene3D G3DSA:1.10.340.30 5 189 3.2E-80 T 13-10-2018 Astex_3472 b219e45b47a142ac019a8d62a7cd383b 189 Pfam PF03352 Methyladenine glycosylase 10 186 4.7E-77 T 13-10-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 Astex_1660 20e5f8d9c8646fa4bbca0e1ffd2d06c3 344 Gene3D G3DSA:3.40.50.300 2 253 1.1E-80 T 13-10-2018 Astex_1660 20e5f8d9c8646fa4bbca0e1ffd2d06c3 344 Pfam PF12857 TOBE-like domain 286 338 1.4E-6 T 13-10-2018 IPR024765 TOBE-like domain KEGG: 00920+3.6.3.25 Astex_1660 20e5f8d9c8646fa4bbca0e1ffd2d06c3 344 SUPERFAMILY SSF50331 241 340 5.04E-5 T 13-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal Astex_1660 20e5f8d9c8646fa4bbca0e1ffd2d06c3 344 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Astex_1660 20e5f8d9c8646fa4bbca0e1ffd2d06c3 344 SMART SM00382 27 214 2.9E-18 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_1660 20e5f8d9c8646fa4bbca0e1ffd2d06c3 344 SUPERFAMILY SSF52540 3 243 3.84E-86 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1660 20e5f8d9c8646fa4bbca0e1ffd2d06c3 344 Pfam PF00005 ABC transporter 18 164 2.5E-35 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_1660 20e5f8d9c8646fa4bbca0e1ffd2d06c3 344 TIGRFAM TIGR00968 3a0106s01: sulfate ABC transporter, ATP-binding protein 4 242 7.0E-109 T 13-10-2018 IPR005666 Sulphate transport system permease protein 1 GO:0008272|GO:0015419|GO:0016020|GO:0043190 KEGG: 00920+3.6.3.25 Astex_2278 87524e5d3328f06700970e3cbaaa5ad6 240 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 128 160 3.8E-5 T 13-10-2018 IPR001451 Hexapeptide repeat Astex_2278 87524e5d3328f06700970e3cbaaa5ad6 240 Gene3D G3DSA:2.160.10.10 22 224 1.9E-42 T 13-10-2018 Astex_2278 87524e5d3328f06700970e3cbaaa5ad6 240 SUPERFAMILY SSF51161 38 200 7.49E-30 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily Astex_2278 87524e5d3328f06700970e3cbaaa5ad6 240 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 136 164 - T 13-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 Astex_3542 fd93444ae0fbf18575fe01f6ec7b2271 196 Gene3D G3DSA:3.10.450.50 32 196 6.8E-22 T 13-10-2018 Astex_3542 fd93444ae0fbf18575fe01f6ec7b2271 196 PIRSF PIRSF028288 6 196 6.5E-82 T 13-10-2018 IPR016878 Uncharacterised conserved protein UCP028288 Astex_0104 9e647386d39ef533755d7ac2d466a422 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.2E-6 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0104 9e647386d39ef533755d7ac2d466a422 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 1.2E-6 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0104 9e647386d39ef533755d7ac2d466a422 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 1.2E-6 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0104 9e647386d39ef533755d7ac2d466a422 249 SUPERFAMILY SSF51735 3 248 7.76E-67 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_0104 9e647386d39ef533755d7ac2d466a422 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 4.1E-30 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0104 9e647386d39ef533755d7ac2d466a422 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 4.1E-30 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0104 9e647386d39ef533755d7ac2d466a422 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 4.1E-30 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0104 9e647386d39ef533755d7ac2d466a422 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 4.1E-30 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0104 9e647386d39ef533755d7ac2d466a422 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 4.1E-30 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0104 9e647386d39ef533755d7ac2d466a422 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 4.1E-30 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0104 9e647386d39ef533755d7ac2d466a422 249 Gene3D G3DSA:3.40.50.720 2 248 1.4E-68 T 13-10-2018 Astex_0104 9e647386d39ef533755d7ac2d466a422 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 247 1.6E-48 T 13-10-2018 Astex_0104 9e647386d39ef533755d7ac2d466a422 249 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 190 0.002 T 13-10-2018 Astex_3551 980df698f731d0a728e955a8096a63f0 440 SUPERFAMILY SSF103473 11 431 2.49E-77 T 13-10-2018 IPR036259 MFS transporter superfamily Astex_3551 980df698f731d0a728e955a8096a63f0 440 Pfam PF07690 Major Facilitator Superfamily 24 385 3.5E-52 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Astex_3551 980df698f731d0a728e955a8096a63f0 440 Gene3D G3DSA:1.20.1250.20 11 207 7.5E-46 T 13-10-2018 Astex_3551 980df698f731d0a728e955a8096a63f0 440 PIRSF PIRSF002808 8 437 6.8E-34 T 13-10-2018 IPR000849 Sugar phosphate transporter GO:0016021|GO:0022857|GO:0055085 Astex_3551 980df698f731d0a728e955a8096a63f0 440 Gene3D G3DSA:1.20.1250.20 225 431 4.4E-27 T 13-10-2018 Astex_0615 020181e4733f0d6c29a2ac59126ec6cb 147 SMART SM00260 1 139 7.0E-23 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 Astex_0615 020181e4733f0d6c29a2ac59126ec6cb 147 SUPERFAMILY SSF50341 2 142 2.09E-28 T 13-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 Astex_0615 020181e4733f0d6c29a2ac59126ec6cb 147 Pfam PF01584 CheW-like domain 6 141 6.7E-25 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 Astex_0615 020181e4733f0d6c29a2ac59126ec6cb 147 Gene3D G3DSA:2.40.50.180 24 134 2.7E-27 T 13-10-2018 Astex_0615 020181e4733f0d6c29a2ac59126ec6cb 147 Gene3D G3DSA:2.30.30.40 7 133 2.7E-27 T 13-10-2018 Astex_2369 7c566b946bd423325a7f374b2e59cff0 113 Gene3D G3DSA:3.30.2310.20 2 106 8.3E-18 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Astex_2369 7c566b946bd423325a7f374b2e59cff0 113 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 10 101 6.1E-16 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family Astex_2369 7c566b946bd423325a7f374b2e59cff0 113 SUPERFAMILY SSF143011 9 101 5.1E-6 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Astex_1530 9d46abe7ea158f7f068c4d0bb9e9a2ff 383 Pfam PF10098 Uncharacterised protein conserved in bacteria (DUF2336) 93 349 1.1E-79 T 13-10-2018 IPR019285 Protein of unknown function DUF2336 Astex_1530 9d46abe7ea158f7f068c4d0bb9e9a2ff 383 PIRSF PIRSF035865 3 379 2.2E-110 T 13-10-2018 IPR014598 Uncharacterised conserved protein UCP035865 Astex_2175 ac0e65a9980629081547e01216247b1a 93 Gene3D G3DSA:3.30.2310.20 1 93 7.6E-23 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Astex_2175 ac0e65a9980629081547e01216247b1a 93 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 3 92 1.5E-14 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family Astex_2175 ac0e65a9980629081547e01216247b1a 93 TIGRFAM TIGR02385 RelE_StbE: addiction module toxin, RelE/StbE family 3 92 1.7E-11 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family Astex_3325 64f1e142fefb22879aad6c989d6452c6 140 Gene3D G3DSA:3.40.50.12740 17 137 7.6E-32 T 13-10-2018 Astex_3325 64f1e142fefb22879aad6c989d6452c6 140 SUPERFAMILY SSF52172 16 131 2.28E-30 T 13-10-2018 IPR011006 CheY-like superfamily Astex_3325 64f1e142fefb22879aad6c989d6452c6 140 Pfam PF00072 Response regulator receiver domain 20 131 1.2E-19 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_3325 64f1e142fefb22879aad6c989d6452c6 140 SMART SM00448 18 131 4.6E-25 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_2688 7186d749a34de1681c7e7a10779b4aba 231 Gene3D G3DSA:1.10.10.10 122 228 2.2E-13 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_2688 7186d749a34de1681c7e7a10779b4aba 231 SMART SM00862 154 224 2.4E-9 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Astex_2688 7186d749a34de1681c7e7a10779b4aba 231 SMART SM00448 4 114 2.3E-36 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_2688 7186d749a34de1681c7e7a10779b4aba 231 SUPERFAMILY SSF52172 2 126 1.85E-35 T 13-10-2018 IPR011006 CheY-like superfamily Astex_2688 7186d749a34de1681c7e7a10779b4aba 231 SUPERFAMILY SSF46894 129 224 3.12E-14 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Astex_2688 7186d749a34de1681c7e7a10779b4aba 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 157 224 2.7E-8 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Astex_2688 7186d749a34de1681c7e7a10779b4aba 231 Gene3D G3DSA:3.40.50.2300 1 121 4.4E-32 T 13-10-2018 Astex_2688 7186d749a34de1681c7e7a10779b4aba 231 Pfam PF00072 Response regulator receiver domain 6 115 2.7E-24 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_2514 308f620423fc197fbf8bbd1113c2e73f 248 TIGRFAM TIGR00685 T6PP: trehalose-phosphatase 9 242 5.8E-40 T 13-10-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 Astex_2514 308f620423fc197fbf8bbd1113c2e73f 248 SUPERFAMILY SSF56784 13 244 5.66E-37 T 13-10-2018 IPR036412 HAD-like superfamily Astex_2514 308f620423fc197fbf8bbd1113c2e73f 248 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 14 208 7.9E-13 T 13-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 Astex_2514 308f620423fc197fbf8bbd1113c2e73f 248 Gene3D G3DSA:3.40.50.1000 14 230 5.7E-45 T 13-10-2018 IPR023214 HAD superfamily Astex_2514 308f620423fc197fbf8bbd1113c2e73f 248 Gene3D G3DSA:3.30.70.1020 96 170 5.7E-45 T 13-10-2018 Astex_2514 308f620423fc197fbf8bbd1113c2e73f 248 Pfam PF02358 Trehalose-phosphatase 15 230 9.1E-31 T 13-10-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 Astex_3370 58de0ddfe4875c96d97c32be2f1616a5 396 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 290 296 - T 13-10-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 Reactome: R-HSA-9033241 Astex_3370 58de0ddfe4875c96d97c32be2f1616a5 396 Pfam PF01070 FMN-dependent dehydrogenase 30 392 4.6E-127 T 13-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 Astex_3370 58de0ddfe4875c96d97c32be2f1616a5 396 Hamap MF_01559 L-lactate dehydrogenase [lldD]. 18 396 72.999 T 13-10-2018 IPR020920 L-lactate dehydrogenase, bacterial GO:0004457|GO:0006089|GO:0010181|GO:0055114 Astex_3370 58de0ddfe4875c96d97c32be2f1616a5 396 PIRSF PIRSF000138 3 396 4.1E-123 T 13-10-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 Reactome: R-HSA-9033241 Astex_3370 58de0ddfe4875c96d97c32be2f1616a5 396 SUPERFAMILY SSF51395 24 392 2.93E-100 T 13-10-2018 Astex_3370 58de0ddfe4875c96d97c32be2f1616a5 396 Gene3D G3DSA:3.20.20.70 20 395 7.8E-127 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_3379 b8f950fc2504fb7a36addcb453e2a8d1 456 Gene3D G3DSA:2.20.200.10 100 343 2.4E-124 T 13-10-2018 Astex_3379 b8f950fc2504fb7a36addcb453e2a8d1 456 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 13 454 2.8E-108 T 13-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 Astex_3379 b8f950fc2504fb7a36addcb453e2a8d1 456 Gene3D G3DSA:1.20.1600.10 54 454 2.4E-124 T 13-10-2018 Astex_3379 b8f950fc2504fb7a36addcb453e2a8d1 456 SUPERFAMILY SSF56954 4 455 9.55E-104 T 13-10-2018 Astex_3379 b8f950fc2504fb7a36addcb453e2a8d1 456 Pfam PF02321 Outer membrane efflux protein 272 452 1.6E-26 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Astex_3379 b8f950fc2504fb7a36addcb453e2a8d1 456 Pfam PF02321 Outer membrane efflux protein 63 245 3.2E-26 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Astex_0292 8739c933867bb7de880ebffa89d28d76 125 PIRSF PIRSF007028 11 125 7.8E-41 T 13-10-2018 IPR009874 Protein of unknown function DUF1428 Astex_0292 8739c933867bb7de880ebffa89d28d76 125 SUPERFAMILY SSF54909 12 123 7.51E-46 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel Astex_0292 8739c933867bb7de880ebffa89d28d76 125 Pfam PF07237 Protein of unknown function (DUF1428) 12 111 5.0E-41 T 13-10-2018 IPR009874 Protein of unknown function DUF1428 Astex_0292 8739c933867bb7de880ebffa89d28d76 125 Gene3D G3DSA:3.30.70.100 4 124 1.1E-40 T 13-10-2018 Astex_1578 73952039ad253115290553275dd73a24 162 SUPERFAMILY SSF47226 36 128 3.66E-7 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 Astex_1356 37971ab99fbe209687a5d5c8c871c122 257 SUPERFAMILY SSF110997 179 256 8.5E-7 T 13-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 Astex_1356 37971ab99fbe209687a5d5c8c871c122 257 Pfam PF05036 Sporulation related domain 179 256 6.4E-13 T 13-10-2018 IPR007730 Sporulation-like domain GO:0042834 Astex_0845 acf19310d44aaf409ab051fab6b9e50f 246 Gene3D G3DSA:3.40.50.150 9 178 1.9E-16 T 13-10-2018 Astex_0845 acf19310d44aaf409ab051fab6b9e50f 246 SUPERFAMILY SSF53335 22 210 1.01E-23 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Astex_0845 acf19310d44aaf409ab051fab6b9e50f 246 Pfam PF13489 Methyltransferase domain 42 170 2.6E-9 T 13-10-2018 Astex_2524 e6e795134b7a4616499b69026d6aa02c 456 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 107 451 3.7E-97 T 13-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 Astex_2524 e6e795134b7a4616499b69026d6aa02c 456 Pfam PF07687 Peptidase dimerisation domain 260 356 2.0E-4 T 13-10-2018 IPR011650 Peptidase M20, dimerisation domain Astex_2524 e6e795134b7a4616499b69026d6aa02c 456 PIRSF PIRSF001235 11 79 2.2E-7 T 13-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 Astex_2524 e6e795134b7a4616499b69026d6aa02c 456 PIRSF PIRSF001235 105 456 3.0E-109 T 13-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 Astex_2524 e6e795134b7a4616499b69026d6aa02c 456 Gene3D G3DSA:3.40.630.10 7 89 1.4E-7 T 13-10-2018 Astex_2524 e6e795134b7a4616499b69026d6aa02c 456 Gene3D G3DSA:3.40.630.10 108 445 6.7E-117 T 13-10-2018 Astex_2524 e6e795134b7a4616499b69026d6aa02c 456 SUPERFAMILY SSF53187 107 451 2.6E-61 T 13-10-2018 Astex_2524 e6e795134b7a4616499b69026d6aa02c 456 SUPERFAMILY SSF53187 8 71 2.68E-7 T 13-10-2018 Astex_2524 e6e795134b7a4616499b69026d6aa02c 456 Pfam PF01546 Peptidase family M20/M25/M40 121 449 4.3E-27 T 13-10-2018 IPR002933 Peptidase M20 GO:0016787 Astex_2524 e6e795134b7a4616499b69026d6aa02c 456 Gene3D G3DSA:3.30.70.360 256 370 6.7E-117 T 13-10-2018 Astex_2524 e6e795134b7a4616499b69026d6aa02c 456 SUPERFAMILY SSF55031 258 371 6.13E-27 T 13-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain Astex_1927 1602414f03216b9e52ccb0534eeb8b68 704 Gene3D G3DSA:2.170.170.11 131 250 4.2E-247 T 13-10-2018 IPR023310 Malate synthase G, beta sub-domain GO:0004474 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 Astex_1927 1602414f03216b9e52ccb0534eeb8b68 704 Gene3D G3DSA:3.20.20.360 9 562 4.2E-247 T 13-10-2018 Astex_1927 1602414f03216b9e52ccb0534eeb8b68 704 Pfam PF01274 Malate synthase 17 660 8.6E-154 T 13-10-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 Astex_1927 1602414f03216b9e52ccb0534eeb8b68 704 SUPERFAMILY SSF51645 3 699 2.62E-266 T 13-10-2018 IPR011076 Malate synthase-like superfamily GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 Astex_1927 1602414f03216b9e52ccb0534eeb8b68 704 Hamap MF_00641 Malate synthase G [glcB]. 1 704 338.068 T 13-10-2018 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 Astex_1927 1602414f03216b9e52ccb0534eeb8b68 704 Gene3D G3DSA:1.20.1220.12 563 704 2.0E-65 T 13-10-2018 Astex_1927 1602414f03216b9e52ccb0534eeb8b68 704 TIGRFAM TIGR01345 malate_syn_G: malate synthase G 5 698 1.1E-300 T 13-10-2018 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 Astex_1754 8672678473861efec22e918fe919d07b 132 Pfam PF03733 Inner membrane component domain 4 54 1.6E-13 T 13-10-2018 IPR005185 Inner membrane component domain Astex_1754 8672678473861efec22e918fe919d07b 132 Pfam PF03733 Inner membrane component domain 76 126 2.1E-15 T 13-10-2018 IPR005185 Inner membrane component domain Astex_1754 8672678473861efec22e918fe919d07b 132 PIRSF PIRSF028777 1 132 1.5E-43 T 13-10-2018 IPR031308 Uncharacterised conserved protein UCP028777 Astex_0792 44555af45b11d463eb9e2cc14cdfe778 173 Pfam PF09351 Domain of unknown function (DUF1993) 9 169 1.7E-61 T 13-10-2018 IPR018531 Protein of unknown function DUF1993 Astex_0792 44555af45b11d463eb9e2cc14cdfe778 173 Gene3D G3DSA:1.20.120.450 3 171 1.4E-55 T 13-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes Astex_0792 44555af45b11d463eb9e2cc14cdfe778 173 SUPERFAMILY SSF109854 8 170 3.84E-60 T 13-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes Astex_3852 910a6ee59134d792a4b0ac235a05a5a4 667 Pfam PF00122 E1-E2 ATPase 168 339 3.5E-51 T 13-10-2018 Astex_3852 910a6ee59134d792a4b0ac235a05a5a4 667 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 361 367 - T 13-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 Astex_3852 910a6ee59134d792a4b0ac235a05a5a4 667 Gene3D G3DSA:2.70.150.20 146 262 5.3E-35 T 13-10-2018 Astex_3852 910a6ee59134d792a4b0ac235a05a5a4 667 Gene3D G3DSA:3.40.50.1000 340 608 4.7E-82 T 13-10-2018 IPR023214 HAD superfamily Astex_3852 910a6ee59134d792a4b0ac235a05a5a4 667 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 107 444 1.3E-94 T 13-10-2018 Astex_3852 910a6ee59134d792a4b0ac235a05a5a4 667 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 579 591 7.2E-28 T 13-10-2018 Astex_3852 910a6ee59134d792a4b0ac235a05a5a4 667 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 359 373 7.2E-28 T 13-10-2018 Astex_3852 910a6ee59134d792a4b0ac235a05a5a4 667 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 556 575 7.2E-28 T 13-10-2018 Astex_3852 910a6ee59134d792a4b0ac235a05a5a4 667 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 208 222 7.2E-28 T 13-10-2018 Astex_3852 910a6ee59134d792a4b0ac235a05a5a4 667 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 504 514 7.2E-28 T 13-10-2018 Astex_3852 910a6ee59134d792a4b0ac235a05a5a4 667 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 482 493 7.2E-28 T 13-10-2018 Astex_3852 910a6ee59134d792a4b0ac235a05a5a4 667 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 107 658 1.7E-179 T 13-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 Astex_3852 910a6ee59134d792a4b0ac235a05a5a4 667 Gene3D G3DSA:3.40.1110.10 370 489 4.7E-82 T 13-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 Astex_3852 910a6ee59134d792a4b0ac235a05a5a4 667 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 125 658 7.3E-126 T 13-10-2018 Astex_3852 910a6ee59134d792a4b0ac235a05a5a4 667 PRINTS PR00941 Cadmium-transporting ATPase signature 142 162 1.6E-11 T 13-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 Astex_3852 910a6ee59134d792a4b0ac235a05a5a4 667 PRINTS PR00941 Cadmium-transporting ATPase signature 243 257 1.6E-11 T 13-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 Astex_3852 910a6ee59134d792a4b0ac235a05a5a4 667 PRINTS PR00941 Cadmium-transporting ATPase signature 224 240 1.6E-11 T 13-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 Astex_3852 910a6ee59134d792a4b0ac235a05a5a4 667 SUPERFAMILY SSF81653 169 258 3.4E-25 T 13-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 Astex_3852 910a6ee59134d792a4b0ac235a05a5a4 667 SUPERFAMILY SSF56784 358 656 3.68E-51 T 13-10-2018 IPR036412 HAD-like superfamily Astex_3852 910a6ee59134d792a4b0ac235a05a5a4 667 Pfam PF00702 haloacid dehalogenase-like hydrolase 357 570 2.9E-36 T 13-10-2018 Astex_3852 910a6ee59134d792a4b0ac235a05a5a4 667 SUPERFAMILY SSF81665 110 644 2.62E-14 T 13-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 Astex_3852 910a6ee59134d792a4b0ac235a05a5a4 667 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 130 635 1.7E-87 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 Astex_1454 a51c3405f94593e7c7f35949ceff1943 488 PIRSF PIRSF038928 3 488 2.8E-216 T 13-10-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Astex_1454 a51c3405f94593e7c7f35949ceff1943 488 SUPERFAMILY SSF56634 11 485 3.79E-203 T 13-10-2018 IPR020835 Catalase superfamily GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Astex_1454 a51c3405f94593e7c7f35949ceff1943 488 Pfam PF00199 Catalase 15 397 2.7E-182 T 13-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Astex_1454 a51c3405f94593e7c7f35949ceff1943 488 Gene3D G3DSA:2.40.180.10 9 488 1.5E-215 T 13-10-2018 IPR037060 Catalase core domain superfamily GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 Astex_1454 a51c3405f94593e7c7f35949ceff1943 488 Pfam PF06628 Catalase-related immune-responsive 424 484 4.9E-21 T 13-10-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Astex_1454 a51c3405f94593e7c7f35949ceff1943 488 PRINTS PR00067 Catalase signature 28 51 2.5E-71 T 13-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Astex_1454 a51c3405f94593e7c7f35949ceff1943 488 PRINTS PR00067 Catalase signature 130 148 2.5E-71 T 13-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Astex_1454 a51c3405f94593e7c7f35949ceff1943 488 PRINTS PR00067 Catalase signature 327 353 2.5E-71 T 13-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Astex_1454 a51c3405f94593e7c7f35949ceff1943 488 PRINTS PR00067 Catalase signature 295 322 2.5E-71 T 13-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Astex_1454 a51c3405f94593e7c7f35949ceff1943 488 PRINTS PR00067 Catalase signature 90 108 2.5E-71 T 13-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Astex_1454 a51c3405f94593e7c7f35949ceff1943 488 PRINTS PR00067 Catalase signature 111 128 2.5E-71 T 13-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Astex_1454 a51c3405f94593e7c7f35949ceff1943 488 SMART SM01060 15 400 9.4E-273 T 13-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Astex_1454 a51c3405f94593e7c7f35949ceff1943 488 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 340 348 - T 13-10-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 Astex_2803 0c240732ea0ef1d9d78fa7b07d6f1627 186 Gene3D G3DSA:3.40.50.12280 22 186 2.2E-77 T 13-10-2018 Astex_2803 0c240732ea0ef1d9d78fa7b07d6f1627 186 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 65 174 1.2E-22 T 13-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2803 0c240732ea0ef1d9d78fa7b07d6f1627 186 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 146 162 - T 13-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2803 0c240732ea0ef1d9d78fa7b07d6f1627 186 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 39 180 4.1E-72 T 13-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2803 0c240732ea0ef1d9d78fa7b07d6f1627 186 SUPERFAMILY SSF56770 37 181 4.97E-65 T 13-10-2018 Astex_2803 0c240732ea0ef1d9d78fa7b07d6f1627 186 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 28 179 39.374 T 13-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2275 f075264b2436c7adba9621d985edfe52 364 SUPERFAMILY SSF53756 6 164 2.41E-8 T 13-10-2018 Astex_1641 10f107b4690b709efe0dbdae339a2234 129 SUPERFAMILY SSF54593 14 120 1.07E-13 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Astex_1641 10f107b4690b709efe0dbdae339a2234 129 Gene3D G3DSA:3.10.180.10 6 129 2.7E-30 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Astex_1550 a3c4fd7019ac34c886f48d9bae77628a 607 Pfam PF08439 Oligopeptidase F 127 194 4.5E-12 T 13-10-2018 IPR013647 Oligopeptidase F, N-terminal domain Astex_1550 a3c4fd7019ac34c886f48d9bae77628a 607 Gene3D G3DSA:1.20.140.70 31 183 3.0E-9 T 13-10-2018 Astex_1550 a3c4fd7019ac34c886f48d9bae77628a 607 TIGRFAM TIGR02290 M3_fam_3: oligoendopeptidase, pepF/M3 family 20 606 1.3E-186 T 13-10-2018 IPR011977 Peptidase M3B, oligoendopeptidase-related clade 3 Astex_1550 a3c4fd7019ac34c886f48d9bae77628a 607 SUPERFAMILY SSF55486 17 590 1.12E-88 T 13-10-2018 Astex_1550 a3c4fd7019ac34c886f48d9bae77628a 607 Pfam PF01432 Peptidase family M3 216 592 2.5E-33 T 13-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 Astex_1550 a3c4fd7019ac34c886f48d9bae77628a 607 Gene3D G3DSA:1.10.1370.20 240 607 1.1E-104 T 13-10-2018 Astex_2598 c50f936fe7a62c6f56d42188066344e2 381 Pfam PF13379 NMT1-like family 3 257 1.6E-59 T 13-10-2018 Astex_2598 c50f936fe7a62c6f56d42188066344e2 381 Gene3D G3DSA:3.40.190.10 5 346 2.6E-109 T 13-10-2018 Astex_2598 c50f936fe7a62c6f56d42188066344e2 381 SUPERFAMILY SSF53850 4 251 1.54E-20 T 13-10-2018 Astex_2598 c50f936fe7a62c6f56d42188066344e2 381 Gene3D G3DSA:3.40.190.10 90 210 2.6E-109 T 13-10-2018 Astex_0464 949a2022a2bf806f3327dd5254eafaf5 132 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 128 2.2E-5 T 13-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Astex_0464 949a2022a2bf806f3327dd5254eafaf5 132 SUPERFAMILY SSF54593 4 130 1.51E-19 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Astex_0464 949a2022a2bf806f3327dd5254eafaf5 132 Gene3D G3DSA:3.10.180.10 1 132 1.2E-18 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Astex_1196 4578054095c52ee7d50ad3da6efa4414 547 SUPERFAMILY SSF52029 184 376 1.02E-86 T 13-10-2018 IPR027409 GroEL-like apical domain superfamily Astex_1196 4578054095c52ee7d50ad3da6efa4414 547 Gene3D G3DSA:1.10.560.10 8 522 2.4E-239 T 13-10-2018 IPR027413 GroEL-like equatorial domain superfamily Astex_1196 4578054095c52ee7d50ad3da6efa4414 547 Gene3D G3DSA:3.50.7.10 192 372 2.4E-239 T 13-10-2018 IPR027409 GroEL-like apical domain superfamily Astex_1196 4578054095c52ee7d50ad3da6efa4414 547 Gene3D G3DSA:3.30.260.10 136 410 2.4E-239 T 13-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily Astex_1196 4578054095c52ee7d50ad3da6efa4414 547 SUPERFAMILY SSF48592 7 522 7.63E-73 T 13-10-2018 IPR027413 GroEL-like equatorial domain superfamily Astex_1196 4578054095c52ee7d50ad3da6efa4414 547 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 524 2.2E-97 T 13-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 Astex_1196 4578054095c52ee7d50ad3da6efa4414 547 Hamap MF_00600 60 kDa chaperonin [groL]. 2 545 42.544 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 Astex_1196 4578054095c52ee7d50ad3da6efa4414 547 PRINTS PR00298 60kDa chaperonin signature 268 291 2.2E-74 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 Astex_1196 4578054095c52ee7d50ad3da6efa4414 547 PRINTS PR00298 60kDa chaperonin signature 350 375 2.2E-74 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 Astex_1196 4578054095c52ee7d50ad3da6efa4414 547 PRINTS PR00298 60kDa chaperonin signature 83 110 2.2E-74 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 Astex_1196 4578054095c52ee7d50ad3da6efa4414 547 PRINTS PR00298 60kDa chaperonin signature 27 53 2.2E-74 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 Astex_1196 4578054095c52ee7d50ad3da6efa4414 547 PRINTS PR00298 60kDa chaperonin signature 398 419 2.2E-74 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 Astex_1196 4578054095c52ee7d50ad3da6efa4414 547 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 527 4.1E-258 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 Astex_1196 4578054095c52ee7d50ad3da6efa4414 547 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 13-10-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 Astex_1196 4578054095c52ee7d50ad3da6efa4414 547 SUPERFAMILY SSF54849 137 203 4.35E-24 T 13-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily Astex_1718 4caf3c2c2f2c6964daa254497f76c60e 286 Gene3D G3DSA:3.40.50.720 15 284 5.8E-47 T 13-10-2018 Astex_1718 4caf3c2c2f2c6964daa254497f76c60e 286 SUPERFAMILY SSF51735 17 206 6.3E-42 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_1718 4caf3c2c2f2c6964daa254497f76c60e 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 1.6E-14 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1718 4caf3c2c2f2c6964daa254497f76c60e 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 1.6E-14 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1718 4caf3c2c2f2c6964daa254497f76c60e 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 20 37 1.6E-14 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1718 4caf3c2c2f2c6964daa254497f76c60e 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 1.6E-14 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1718 4caf3c2c2f2c6964daa254497f76c60e 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 1.6E-14 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1718 4caf3c2c2f2c6964daa254497f76c60e 286 Pfam PF00106 short chain dehydrogenase 21 196 7.8E-35 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1009 fb6db8f3207e52089cd543621e8908f8 278 Pfam PF01987 Mitochondrial biogenesis AIM24 23 240 5.1E-64 T 13-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 Astex_1009 fb6db8f3207e52089cd543621e8908f8 278 SUPERFAMILY SSF51219 21 254 2.41E-78 T 13-10-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain superfamily Astex_1009 fb6db8f3207e52089cd543621e8908f8 278 Gene3D G3DSA:3.60.160.10 15 262 2.4E-94 T 13-10-2018 IPR036983 Mitochondrial biogenesis AIM24 superfamily Astex_1009 fb6db8f3207e52089cd543621e8908f8 278 TIGRFAM TIGR00266 TIGR00266: TIGR00266 family protein 23 242 4.5E-29 T 13-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 Astex_2034 4c9bab6bd4db0bcff5d688e4438bdd7d 348 Gene3D G3DSA:3.90.226.40 4 347 1.5E-125 T 13-10-2018 Astex_2034 4c9bab6bd4db0bcff5d688e4438bdd7d 348 SUPERFAMILY SSF52096 8 319 1.77E-66 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Astex_2034 4c9bab6bd4db0bcff5d688e4438bdd7d 348 Pfam PF16113 Enoyl-CoA hydratase/isomerase 19 339 5.2E-120 T 13-10-2018 IPR032259 Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type GO:0003860 Reactome: R-HSA-70895 Astex_0225 8d1b1a39a661e777e0da97fbbb8f7564 132 SUPERFAMILY SSF46785 8 101 4.04E-28 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_0225 8d1b1a39a661e777e0da97fbbb8f7564 132 SMART SM00418 10 88 8.9E-18 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Astex_0225 8d1b1a39a661e777e0da97fbbb8f7564 132 Pfam PF12840 Helix-turn-helix domain 12 67 2.8E-15 T 13-10-2018 Astex_0225 8d1b1a39a661e777e0da97fbbb8f7564 132 Gene3D G3DSA:1.10.10.10 3 110 1.7E-31 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_0225 8d1b1a39a661e777e0da97fbbb8f7564 132 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 31 42 6.1E-10 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Astex_0225 8d1b1a39a661e777e0da97fbbb8f7564 132 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 12 27 6.1E-10 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Astex_0225 8d1b1a39a661e777e0da97fbbb8f7564 132 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 44 59 6.1E-10 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Astex_0225 8d1b1a39a661e777e0da97fbbb8f7564 132 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 74 6.1E-10 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Astex_0832 d9ae82d4ac83c4ac19f5ca7ef1a030ec 139 SUPERFAMILY SSF161084 6 132 2.55E-16 T 13-10-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamily Astex_0832 d9ae82d4ac83c4ac19f5ca7ef1a030ec 139 Pfam PF01124 MAPEG family 8 134 6.9E-15 T 13-10-2018 IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein Astex_0832 d9ae82d4ac83c4ac19f5ca7ef1a030ec 139 Gene3D G3DSA:1.20.120.550 10 137 4.8E-12 T 13-10-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamily Astex_3791 631e0492d5bb4133b10a891ce999fa98 157 Pfam PF09677 Type-F conjugative transfer system protein (TrbI_Ftype) 37 135 2.8E-7 T 13-10-2018 IPR014115 Type-F conjugative transfer system protein TrbI Astex_0587 6596092de2900bb7220334d63ce67271 718 SUPERFAMILY SSF64518 151 718 6.8E-8 T 13-10-2018 Astex_0587 6596092de2900bb7220334d63ce67271 718 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 666 716 4.4E-9 T 13-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain Astex_0587 6596092de2900bb7220334d63ce67271 718 PRINTS PR01005 Flagellar hook-associated protein signature 13 36 1.1E-8 T 13-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 Astex_0587 6596092de2900bb7220334d63ce67271 718 PRINTS PR01005 Flagellar hook-associated protein signature 155 179 1.1E-8 T 13-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 Astex_0587 6596092de2900bb7220334d63ce67271 718 PRINTS PR01005 Flagellar hook-associated protein signature 213 231 1.1E-8 T 13-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 Astex_0587 6596092de2900bb7220334d63ce67271 718 PRINTS PR01005 Flagellar hook-associated protein signature 122 142 1.1E-8 T 13-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 Astex_0587 6596092de2900bb7220334d63ce67271 718 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 5 365 9.1E-57 T 13-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 Astex_0587 6596092de2900bb7220334d63ce67271 718 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 13 33 - T 13-10-2018 IPR019776 Flagellar basal body rod protein, conserved site Astex_0587 6596092de2900bb7220334d63ce67271 718 Pfam PF00460 Flagella basal body rod protein 7 36 3.4E-9 T 13-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 Astex_1681 ecd5aabd3696b98c3db63d146c1871ad 268 Gene3D G3DSA:3.30.1150.10 153 264 2.0E-5 T 13-10-2018 Astex_2782 9d21464b6e0d7aef58e1487c6919d985 124 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 94 3.0E-23 T 13-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_2782 9d21464b6e0d7aef58e1487c6919d985 124 Gene3D G3DSA:3.30.70.60 1 101 8.5E-27 T 13-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 Astex_2782 9d21464b6e0d7aef58e1487c6919d985 124 Pfam PF01250 Ribosomal protein S6 4 92 2.8E-26 T 13-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_2782 9d21464b6e0d7aef58e1487c6919d985 124 SUPERFAMILY SSF54995 1 102 2.75E-31 T 13-10-2018 IPR035980 Ribosomal protein S6 superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_2782 9d21464b6e0d7aef58e1487c6919d985 124 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 19.791 T 13-10-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 Astex_1107 f88dbf3defc1844e1ddcf97c818d5fc9 506 PRINTS PR00344 Bacterial sensor protein C-terminal signature 478 491 8.7E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1107 f88dbf3defc1844e1ddcf97c818d5fc9 506 PRINTS PR00344 Bacterial sensor protein C-terminal signature 419 433 8.7E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1107 f88dbf3defc1844e1ddcf97c818d5fc9 506 PRINTS PR00344 Bacterial sensor protein C-terminal signature 437 447 8.7E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1107 f88dbf3defc1844e1ddcf97c818d5fc9 506 PRINTS PR00344 Bacterial sensor protein C-terminal signature 453 471 8.7E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1107 f88dbf3defc1844e1ddcf97c818d5fc9 506 SMART SM00388 275 339 4.5E-11 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_1107 f88dbf3defc1844e1ddcf97c818d5fc9 506 Pfam PF13493 Domain of unknown function (DUF4118) 26 131 8.7E-18 T 13-10-2018 IPR025201 Sensor protein KdpD, transmembrane domain Astex_1107 f88dbf3defc1844e1ddcf97c818d5fc9 506 Gene3D G3DSA:1.10.287.130 269 337 5.9E-10 T 13-10-2018 Astex_1107 f88dbf3defc1844e1ddcf97c818d5fc9 506 SUPERFAMILY SSF55874 330 491 5.37E-33 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_1107 f88dbf3defc1844e1ddcf97c818d5fc9 506 SUPERFAMILY SSF47384 263 339 2.55E-11 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Astex_1107 f88dbf3defc1844e1ddcf97c818d5fc9 506 Pfam PF00512 His Kinase A (phospho-acceptor) domain 277 339 1.3E-9 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_1107 f88dbf3defc1844e1ddcf97c818d5fc9 506 Gene3D G3DSA:3.30.565.10 338 492 3.8E-32 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_1107 f88dbf3defc1844e1ddcf97c818d5fc9 506 SMART SM00387 382 494 9.5E-31 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_1107 f88dbf3defc1844e1ddcf97c818d5fc9 506 Gene3D G3DSA:3.30.450.40 137 268 8.7E-13 T 13-10-2018 IPR029016 GAF-like domain superfamily Astex_1107 f88dbf3defc1844e1ddcf97c818d5fc9 506 Gene3D G3DSA:1.20.120.620 21 126 1.1E-13 T 13-10-2018 IPR038318 KdpD, transmembrane domain superfamily Astex_1107 f88dbf3defc1844e1ddcf97c818d5fc9 506 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 389 492 2.2E-20 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_1949 2a108e1dfd825998bfd4a558dc25fd6f 352 Pfam PF00356 Bacterial regulatory proteins, lacI family 17 62 6.7E-19 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Astex_1949 2a108e1dfd825998bfd4a558dc25fd6f 352 Gene3D G3DSA:3.40.50.2300 70 322 3.9E-71 T 13-10-2018 Astex_1949 2a108e1dfd825998bfd4a558dc25fd6f 352 ProSitePatterns PS00356 LacI-type HTH domain signature. 18 36 - T 13-10-2018 Astex_1949 2a108e1dfd825998bfd4a558dc25fd6f 352 SMART SM00354 15 85 9.4E-26 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Astex_1949 2a108e1dfd825998bfd4a558dc25fd6f 352 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 17 27 7.4E-6 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Astex_1949 2a108e1dfd825998bfd4a558dc25fd6f 352 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 27 37 7.4E-6 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Astex_1949 2a108e1dfd825998bfd4a558dc25fd6f 352 SUPERFAMILY SSF47413 16 73 2.19E-18 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Astex_1949 2a108e1dfd825998bfd4a558dc25fd6f 352 Gene3D G3DSA:1.10.260.40 15 69 2.1E-24 T 13-10-2018 Astex_1949 2a108e1dfd825998bfd4a558dc25fd6f 352 Gene3D G3DSA:3.40.50.2300 176 305 3.9E-71 T 13-10-2018 Astex_1949 2a108e1dfd825998bfd4a558dc25fd6f 352 SUPERFAMILY SSF53822 76 350 3.0E-71 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Astex_1949 2a108e1dfd825998bfd4a558dc25fd6f 352 Pfam PF13377 Periplasmic binding protein-like domain 184 349 5.7E-37 T 13-10-2018 Astex_1078 27354cfdd91bd0d81b147c12b1d1db27 405 SUPERFAMILY SSF53901 283 404 7.79E-41 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 Astex_1078 27354cfdd91bd0d81b147c12b1d1db27 405 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 10 403 3.3E-124 T 13-10-2018 IPR002155 Thiolase GO:0016747 Astex_1078 27354cfdd91bd0d81b147c12b1d1db27 405 PIRSF PIRSF000429 6 405 1.6E-110 T 13-10-2018 IPR002155 Thiolase GO:0016747 Astex_1078 27354cfdd91bd0d81b147c12b1d1db27 405 ProSitePatterns PS00099 Thiolases active site. 386 399 - T 13-10-2018 IPR020610 Thiolase, active site GO:0016747 Astex_1078 27354cfdd91bd0d81b147c12b1d1db27 405 Pfam PF00108 Thiolase, N-terminal domain 9 232 3.4E-47 T 13-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 Astex_1078 27354cfdd91bd0d81b147c12b1d1db27 405 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 91 109 - T 13-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 Astex_1078 27354cfdd91bd0d81b147c12b1d1db27 405 Gene3D G3DSA:3.40.47.10 129 400 5.4E-135 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 Astex_1078 27354cfdd91bd0d81b147c12b1d1db27 405 SUPERFAMILY SSF53901 5 277 7.28E-61 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 Astex_1078 27354cfdd91bd0d81b147c12b1d1db27 405 ProSitePatterns PS00737 Thiolases signature 2. 351 367 - T 13-10-2018 IPR020613 Thiolase, conserved site GO:0016747 Astex_1078 27354cfdd91bd0d81b147c12b1d1db27 405 Gene3D G3DSA:3.40.47.10 10 302 5.4E-135 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 Astex_1078 27354cfdd91bd0d81b147c12b1d1db27 405 Pfam PF02803 Thiolase, C-terminal domain 282 404 1.2E-43 T 13-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 Astex_2859 877c89f7e9a7b4dacf860f244cb12262 429 Gene3D G3DSA:1.10.580.10 58 411 1.2E-141 T 13-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 Astex_2859 877c89f7e9a7b4dacf860f244cb12262 429 Pfam PF00285 Citrate synthase, C-terminal domain 47 411 8.3E-130 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 Astex_2859 877c89f7e9a7b4dacf860f244cb12262 429 Gene3D G3DSA:1.10.230.10 269 376 1.2E-141 T 13-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain Astex_2859 877c89f7e9a7b4dacf860f244cb12262 429 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 14 422 2.3E-228 T 13-10-2018 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 Astex_2859 877c89f7e9a7b4dacf860f244cb12262 429 PIRSF PIRSF001369 38 429 1.7E-162 T 13-10-2018 IPR024176 Citrate synthase, bacterial-type Astex_2859 877c89f7e9a7b4dacf860f244cb12262 429 SUPERFAMILY SSF48256 9 428 6.28E-162 T 13-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 Astex_2859 877c89f7e9a7b4dacf860f244cb12262 429 PRINTS PR00143 Citrate synthase signature 220 235 4.5E-54 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 Astex_2859 877c89f7e9a7b4dacf860f244cb12262 429 PRINTS PR00143 Citrate synthase signature 359 375 4.5E-54 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 Astex_2859 877c89f7e9a7b4dacf860f244cb12262 429 PRINTS PR00143 Citrate synthase signature 379 393 4.5E-54 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 Astex_2859 877c89f7e9a7b4dacf860f244cb12262 429 PRINTS PR00143 Citrate synthase signature 242 270 4.5E-54 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 Astex_2859 877c89f7e9a7b4dacf860f244cb12262 429 PRINTS PR00143 Citrate synthase signature 295 315 4.5E-54 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 Astex_2859 877c89f7e9a7b4dacf860f244cb12262 429 PRINTS PR00143 Citrate synthase signature 166 179 4.5E-54 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 Astex_2859 877c89f7e9a7b4dacf860f244cb12262 429 ProSitePatterns PS00480 Citrate synthase signature. 302 314 - T 13-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 Astex_2859 877c89f7e9a7b4dacf860f244cb12262 429 Gene3D G3DSA:2.20.28.60 2 51 2.0E-19 T 13-10-2018 Astex_2454 a3bdc0e76f2201b92b0d9598381a8a86 97 Pfam PF12728 Helix-turn-helix domain 36 82 3.9E-8 T 13-10-2018 Astex_2454 a3bdc0e76f2201b92b0d9598381a8a86 97 SUPERFAMILY SSF46955 36 85 2.5E-10 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily Astex_1609 c038520508d6e4f494dceac7020227d3 257 Gene3D G3DSA:3.40.50.720 7 257 2.5E-66 T 13-10-2018 Astex_1609 c038520508d6e4f494dceac7020227d3 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 246 2.9E-39 T 13-10-2018 Astex_1609 c038520508d6e4f494dceac7020227d3 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 6.9E-25 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1609 c038520508d6e4f494dceac7020227d3 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 6.9E-25 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1609 c038520508d6e4f494dceac7020227d3 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 6.9E-25 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1609 c038520508d6e4f494dceac7020227d3 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 6.9E-25 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1609 c038520508d6e4f494dceac7020227d3 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 6.9E-25 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1609 c038520508d6e4f494dceac7020227d3 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 2.6E-5 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1609 c038520508d6e4f494dceac7020227d3 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 2.6E-5 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1609 c038520508d6e4f494dceac7020227d3 257 SUPERFAMILY SSF51735 11 247 4.48E-62 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_3257 be33f8ad9d5d9ec0231c966d6af4fff1 332 Gene3D G3DSA:3.10.50.40 146 246 2.2E-22 T 13-10-2018 Astex_3257 be33f8ad9d5d9ec0231c966d6af4fff1 332 SUPERFAMILY SSF109998 39 177 3.3E-13 T 13-10-2018 IPR027304 Trigger factor/SurA domain superfamily Astex_3257 be33f8ad9d5d9ec0231c966d6af4fff1 332 Pfam PF13145 PPIC-type PPIASE domain 129 252 9.1E-17 T 13-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 Astex_3257 be33f8ad9d5d9ec0231c966d6af4fff1 332 SUPERFAMILY SSF54534 149 241 4.91E-22 T 13-10-2018 Astex_0696 8d870fd66588ec8633138a6d95457622 123 SMART SM00448 1 114 4.4E-23 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_0696 8d870fd66588ec8633138a6d95457622 123 Gene3D G3DSA:3.40.50.12740 1 123 3.3E-28 T 13-10-2018 Astex_0696 8d870fd66588ec8633138a6d95457622 123 SUPERFAMILY SSF52172 1 118 7.26E-30 T 13-10-2018 IPR011006 CheY-like superfamily Astex_0696 8d870fd66588ec8633138a6d95457622 123 Pfam PF00072 Response regulator receiver domain 3 114 1.6E-19 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_2056 bdddaab17aaa07aa5a610180339b19c9 195 TIGRFAM TIGR02613 mob_myst_B: mobile mystery protein B 12 194 1.4E-81 T 13-10-2018 IPR013436 Mobile mystery protein B Astex_2056 bdddaab17aaa07aa5a610180339b19c9 195 Pfam PF02661 Fic/DOC family 57 149 1.8E-16 T 13-10-2018 IPR003812 Fido domain Astex_2056 bdddaab17aaa07aa5a610180339b19c9 195 SUPERFAMILY SSF140931 37 194 5.49E-33 T 13-10-2018 IPR036597 Fido-like domain superfamily Astex_2056 bdddaab17aaa07aa5a610180339b19c9 195 Gene3D G3DSA:1.10.3290.10 16 195 7.9E-36 T 13-10-2018 IPR036597 Fido-like domain superfamily Astex_2048 ade5dbc8969bd87f120c15437bbab38c 389 Gene3D G3DSA:1.20.140.10 237 389 1.6E-38 T 13-10-2018 Astex_2048 ade5dbc8969bd87f120c15437bbab38c 389 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 17 129 8.4E-33 T 13-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 Astex_2048 ade5dbc8969bd87f120c15437bbab38c 389 Gene3D G3DSA:1.10.540.10 1 131 1.4E-41 T 13-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 Astex_2048 ade5dbc8969bd87f120c15437bbab38c 389 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 236 381 8.3E-27 T 13-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Astex_2048 ade5dbc8969bd87f120c15437bbab38c 389 Gene3D G3DSA:2.40.110.10 132 235 2.8E-36 T 13-10-2018 Astex_2048 ade5dbc8969bd87f120c15437bbab38c 389 SUPERFAMILY SSF47203 239 387 1.06E-39 T 13-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 Astex_2048 ade5dbc8969bd87f120c15437bbab38c 389 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 341 360 - T 13-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 Astex_2048 ade5dbc8969bd87f120c15437bbab38c 389 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 135 147 - T 13-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 Astex_2048 ade5dbc8969bd87f120c15437bbab38c 389 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 133 223 1.3E-21 T 13-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 Astex_2048 ade5dbc8969bd87f120c15437bbab38c 389 SUPERFAMILY SSF56645 4 235 2.62E-78 T 13-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 Astex_3064 8ce89d040f0a48aba4068244196e5670 234 Gene3D G3DSA:2.60.120.620 59 234 6.0E-13 T 13-10-2018 Astex_3064 8ce89d040f0a48aba4068244196e5670 234 Pfam PF13661 2OG-Fe(II) oxygenase superfamily 148 233 8.8E-13 T 13-10-2018 IPR039558 Prolyl 3,4-dihydroxylase TPA1/OFD1, N-terminal domain Astex_1142 23b9d297b8b39bd06dce665b20188e37 431 SUPERFAMILY SSF81648 279 414 4.71E-36 T 13-10-2018 IPR036150 Cytochrome b/b6, C-terminal domain superfamily GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 Astex_1142 23b9d297b8b39bd06dce665b20188e37 431 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 276 365 1.2E-39 T 13-10-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 Astex_1142 23b9d297b8b39bd06dce665b20188e37 431 SUPERFAMILY SSF81342 16 278 5.34E-106 T 13-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 Astex_1142 23b9d297b8b39bd06dce665b20188e37 431 Pfam PF00033 Cytochrome b/b6/petB 33 219 2.2E-74 T 13-10-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 Astex_1142 23b9d297b8b39bd06dce665b20188e37 431 Gene3D G3DSA:1.20.810.10 3 431 4.2E-165 T 13-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 Astex_1142 23b9d297b8b39bd06dce665b20188e37 431 PIRSF PIRSF038885 6 425 3.5E-193 T 13-10-2018 IPR030689 Cytochrome b GO:0006122|GO:0008121|GO:0009055|GO:0045275 Reactome: R-HSA-611105 Astex_0904 18a6fa91206fa65cf2e64a1772f4b460 162 SUPERFAMILY SSF46785 26 159 1.07E-20 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_0904 18a6fa91206fa65cf2e64a1772f4b460 162 Gene3D G3DSA:1.10.10.10 15 102 3.9E-28 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_0904 18a6fa91206fa65cf2e64a1772f4b460 162 Gene3D G3DSA:3.30.1490.190 109 162 3.7E-10 T 13-10-2018 Astex_0904 18a6fa91206fa65cf2e64a1772f4b460 162 Pfam PF01475 Ferric uptake regulator family 34 153 4.7E-7 T 13-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 Astex_2068 571c3f5fe0b20a69b23592d9f5e88a3c 185 SUPERFAMILY SSF52218 1 180 1.97E-42 T 13-10-2018 IPR029039 Flavoprotein-like superfamily Astex_2068 571c3f5fe0b20a69b23592d9f5e88a3c 185 Pfam PF03358 NADPH-dependent FMN reductase 46 121 3.3E-12 T 13-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 Astex_2068 571c3f5fe0b20a69b23592d9f5e88a3c 185 Gene3D G3DSA:3.40.50.360 1 185 2.3E-50 T 13-10-2018 IPR029039 Flavoprotein-like superfamily Astex_2180 6a5cec4ab4b12fde3360d45f0893aaae 337 Pfam PF01757 Acyltransferase family 3 320 1.0E-19 T 13-10-2018 IPR002656 Acyltransferase 3 GO:0016747 Astex_1526 b83a6b05f618300e2319622bc07bc5c9 377 Pfam PF02405 Permease MlaE 161 370 3.6E-62 T 13-10-2018 IPR030802 ABC transporter permease MalE GO:0043190 Astex_1526 b83a6b05f618300e2319622bc07bc5c9 377 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 136 372 1.6E-64 T 13-10-2018 IPR003453 ABC transport permease subunit MlaE, Proteobacteria Astex_3418 e1dd87eb207720cd1f031426d7d31b80 336 Gene3D G3DSA:3.90.180.10 21 317 3.7E-80 T 13-10-2018 Astex_3418 e1dd87eb207720cd1f031426d7d31b80 336 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 129 7.8E-32 T 13-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Astex_3418 e1dd87eb207720cd1f031426d7d31b80 336 SUPERFAMILY SSF51735 133 300 1.73E-31 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_3418 e1dd87eb207720cd1f031426d7d31b80 336 SMART SM00829 7 300 0.0061 T 13-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Astex_3418 e1dd87eb207720cd1f031426d7d31b80 336 Gene3D G3DSA:3.40.50.720 147 280 3.7E-80 T 13-10-2018 Astex_3418 e1dd87eb207720cd1f031426d7d31b80 336 Pfam PF00107 Zinc-binding dehydrogenase 169 293 2.2E-17 T 13-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Astex_3418 e1dd87eb207720cd1f031426d7d31b80 336 SUPERFAMILY SSF50129 1 168 1.67E-45 T 13-10-2018 IPR011032 GroES-like superfamily Astex_3045 9013a7020ababbcaa1d20da318fcee84 291 SUPERFAMILY SSF50494 5 191 1.05E-18 T 13-10-2018 IPR009003 Peptidase S1, PA clan Astex_3045 9013a7020ababbcaa1d20da318fcee84 291 Pfam PF13365 Trypsin-like peptidase domain 28 193 1.1E-8 T 13-10-2018 Astex_3045 9013a7020ababbcaa1d20da318fcee84 291 Gene3D G3DSA:2.40.10.120 3 244 2.8E-11 T 13-10-2018 Astex_0677 2ba54f66d2b332459a2ec9dd3d38bd9f 185 SUPERFAMILY SSF55620 3 149 7.23E-20 T 13-10-2018 Astex_0677 2ba54f66d2b332459a2ec9dd3d38bd9f 185 Gene3D G3DSA:3.30.479.10 2 153 9.7E-19 T 13-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 Astex_0677 2ba54f66d2b332459a2ec9dd3d38bd9f 185 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 3 147 8.1E-21 T 13-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 Astex_0117 b5183fe3378fdadeb63062ecbdd34a86 207 Gene3D G3DSA:3.30.160.100 1 107 2.1E-17 T 13-10-2018 IPR036567 Ribosome hibernation promotion factor-like Astex_0117 b5183fe3378fdadeb63062ecbdd34a86 207 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 99 1.4E-14 T 13-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 Astex_0117 b5183fe3378fdadeb63062ecbdd34a86 207 SUPERFAMILY SSF69754 1 104 1.02E-24 T 13-10-2018 IPR036567 Ribosome hibernation promotion factor-like Astex_0117 b5183fe3378fdadeb63062ecbdd34a86 207 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 1 196 19.696 T 13-10-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid Astex_0117 b5183fe3378fdadeb63062ecbdd34a86 207 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 138 191 1.2E-14 T 13-10-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal Astex_0117 b5183fe3378fdadeb63062ecbdd34a86 207 Gene3D G3DSA:3.30.505.50 150 200 7.0E-10 T 13-10-2018 IPR038416 Sigma 54 modulation/S30EA ribosomal protein, C-terminal domain superfamily Astex_0117 b5183fe3378fdadeb63062ecbdd34a86 207 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 96 1.8E-16 T 13-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 Astex_1169 196b576d33717d0e275a0bcb15f6a36c 157 Pfam PF16036 Chalcone isomerase-like 18 155 6.0E-10 T 13-10-2018 IPR016087 Chalcone isomerase GO:0016872 Astex_3488 ff5035a347bcfeeb2929745557925a20 985 Pfam PF13620 Carboxypeptidase regulatory-like domain 46 124 1.4E-10 T 13-10-2018 Astex_3488 ff5035a347bcfeeb2929745557925a20 985 Pfam PF07715 TonB-dependent Receptor Plug Domain 153 244 3.7E-9 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_3488 ff5035a347bcfeeb2929745557925a20 985 SUPERFAMILY SSF56935 131 985 1.22E-59 T 13-10-2018 Astex_3488 ff5035a347bcfeeb2929745557925a20 985 Pfam PF00593 TonB dependent receptor 395 983 3.2E-10 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_3488 ff5035a347bcfeeb2929745557925a20 985 SUPERFAMILY SSF49452 43 124 2.55E-10 T 13-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 Astex_3488 ff5035a347bcfeeb2929745557925a20 985 Gene3D G3DSA:2.170.130.10 126 250 3.2E-9 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_3488 ff5035a347bcfeeb2929745557925a20 985 Gene3D G3DSA:2.60.40.1120 47 125 3.1E-6 T 13-10-2018 Astex_1235 8b8fb9bf03f1d74e629d455ebaf290bf 302 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 126 295 5.2E-24 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Astex_1235 8b8fb9bf03f1d74e629d455ebaf290bf 302 SUPERFAMILY SSF161098 102 287 3.01E-29 T 13-10-2018 IPR035906 MetI-like superfamily Astex_1235 8b8fb9bf03f1d74e629d455ebaf290bf 302 Gene3D G3DSA:1.10.3720.10 103 297 8.6E-24 T 13-10-2018 IPR035906 MetI-like superfamily Astex_1235 8b8fb9bf03f1d74e629d455ebaf290bf 302 TIGRFAM TIGR01183 ntrB: nitrate ABC transporter, permease protein 90 291 2.8E-93 T 13-10-2018 IPR005889 Nitrate transport permease GO:0015112|GO:0015706|GO:0016021 Astex_1882 1f730c0c4b253d3a2635b6ae6fe2ec5a 1099 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 7 83 2.4E-27 T 13-10-2018 IPR013589 Bacterial transglutaminase-like, N-terminal Astex_1882 1f730c0c4b253d3a2635b6ae6fe2ec5a 1099 Pfam PF09899 Putative amidoligase enzyme (DUF2126) 283 1096 0.0 T 13-10-2018 IPR018667 Domain of unknown function DUF2126 Astex_1882 1f730c0c4b253d3a2635b6ae6fe2ec5a 1099 Gene3D G3DSA:3.10.620.30 99 290 9.5E-24 T 13-10-2018 Astex_1882 1f730c0c4b253d3a2635b6ae6fe2ec5a 1099 SUPERFAMILY SSF54001 8 343 8.83E-61 T 13-10-2018 IPR038765 Papain-like cysteine peptidase superfamily Astex_1882 1f730c0c4b253d3a2635b6ae6fe2ec5a 1099 SMART SM00460 178 254 6.4E-16 T 13-10-2018 IPR002931 Transglutaminase-like Astex_1882 1f730c0c4b253d3a2635b6ae6fe2ec5a 1099 Pfam PF01841 Transglutaminase-like superfamily 149 252 2.5E-15 T 13-10-2018 IPR002931 Transglutaminase-like Astex_0662 729ad1dfc6d34768dd722256d28d7f10 206 Pfam PF13338 Transcriptional regulator, AbiEi antitoxin 19 55 1.5E-6 T 13-10-2018 IPR025159 Transcriptional regulator, AbiEi antitoxin Astex_3326 b512ce91ca0b0f4e1c5b0b1fc4d3a8cb 514 Gene3D G3DSA:3.50.50.60 2 508 7.0E-168 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_3326 b512ce91ca0b0f4e1c5b0b1fc4d3a8cb 514 Pfam PF04820 Tryptophan halogenase 7 463 3.0E-121 T 13-10-2018 IPR006905 Flavin-dependent halogenase Astex_3326 b512ce91ca0b0f4e1c5b0b1fc4d3a8cb 514 SUPERFAMILY SSF51905 5 436 2.41E-31 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_3326 b512ce91ca0b0f4e1c5b0b1fc4d3a8cb 514 PIRSF PIRSF011396 1 510 1.5E-139 T 13-10-2018 IPR033856 Flavin-dependent tryptophan halogenase Astex_0389 14ac043e9d0364f54936e465af6f18d1 337 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 22 33 - T 13-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Astex_0389 14ac043e9d0364f54936e465af6f18d1 337 Pfam PF04055 Radical SAM superfamily 20 182 1.3E-25 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Astex_0389 14ac043e9d0364f54936e465af6f18d1 337 Pfam PF06463 Molybdenum Cofactor Synthesis C 188 314 1.8E-38 T 13-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Astex_0389 14ac043e9d0364f54936e465af6f18d1 337 SMART SM00729 16 217 6.3E-10 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Astex_0389 14ac043e9d0364f54936e465af6f18d1 337 Gene3D G3DSA:3.20.20.70 5 337 8.1E-87 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_0389 14ac043e9d0364f54936e465af6f18d1 337 SUPERFAMILY SSF102114 7 280 7.06E-73 T 13-10-2018 Astex_0389 14ac043e9d0364f54936e465af6f18d1 337 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 7 337 3.1E-107 T 13-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Astex_0389 14ac043e9d0364f54936e465af6f18d1 337 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 7 337 37.317 T 13-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 Astex_0389 14ac043e9d0364f54936e465af6f18d1 337 Pfam PF13353 4Fe-4S single cluster domain 23 110 1.7E-8 T 13-10-2018 Astex_1387 6369a2f137808e9d767f31f4027a2597 1040 Gene3D G3DSA:3.55.50.30 22 116 3.0E-17 T 13-10-2018 Astex_1387 6369a2f137808e9d767f31f4027a2597 1040 Pfam PF07715 TonB-dependent Receptor Plug Domain 153 248 8.6E-8 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_1387 6369a2f137808e9d767f31f4027a2597 1040 SUPERFAMILY SSF56935 126 1040 3.66E-66 T 13-10-2018 Astex_1387 6369a2f137808e9d767f31f4027a2597 1040 Gene3D G3DSA:2.170.130.10 128 258 2.2E-8 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_1387 6369a2f137808e9d767f31f4027a2597 1040 Pfam PF00593 TonB dependent receptor 660 1039 6.2E-28 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_1387 6369a2f137808e9d767f31f4027a2597 1040 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 130 1040 7.8E-132 T 13-10-2018 IPR010104 Bacterial TonB-dependent receptor Astex_1387 6369a2f137808e9d767f31f4027a2597 1040 SMART SM00965 52 103 9.2E-11 T 13-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 Astex_2085 0599ffa04aef4a670a1f6b38467f49ab 396 Gene3D G3DSA:1.10.230.10 258 347 2.1E-19 T 13-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain Astex_2085 0599ffa04aef4a670a1f6b38467f49ab 396 Gene3D G3DSA:1.10.580.10 201 373 2.1E-19 T 13-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 Astex_2085 0599ffa04aef4a670a1f6b38467f49ab 396 Pfam PF00285 Citrate synthase, C-terminal domain 188 376 3.4E-24 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 Astex_2085 0599ffa04aef4a670a1f6b38467f49ab 396 SUPERFAMILY SSF48256 77 391 7.59E-28 T 13-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 Astex_2597 61095a025f64ae9b36307187903bcaaf 197 SMART SM01012 129 184 1.1E-22 T 13-10-2018 IPR005561 ANTAR domain GO:0003723 Astex_2597 61095a025f64ae9b36307187903bcaaf 197 Pfam PF03861 ANTAR domain 132 184 1.5E-19 T 13-10-2018 IPR005561 ANTAR domain GO:0003723 Astex_2597 61095a025f64ae9b36307187903bcaaf 197 SUPERFAMILY SSF52172 2 184 6.15E-42 T 13-10-2018 IPR011006 CheY-like superfamily Astex_2597 61095a025f64ae9b36307187903bcaaf 197 PIRSF PIRSF036382 1 191 2.5E-53 T 13-10-2018 IPR008327 Signal transduction response regulator, antiterminator Astex_2597 61095a025f64ae9b36307187903bcaaf 197 Gene3D G3DSA:3.40.50.2300 1 130 2.1E-7 T 13-10-2018 Astex_2597 61095a025f64ae9b36307187903bcaaf 197 Gene3D G3DSA:1.10.10.10 132 191 2.8E-19 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_2400 b5ca670ba894a5abbab277ac3a665a69 325 Pfam PF04773 FecR protein 119 210 1.5E-14 T 13-10-2018 IPR006860 FecR protein Astex_2400 b5ca670ba894a5abbab277ac3a665a69 325 Gene3D G3DSA:2.60.120.1440 111 247 2.2E-17 T 13-10-2018 Astex_2400 b5ca670ba894a5abbab277ac3a665a69 325 Gene3D G3DSA:3.55.50.30 251 325 1.6E-7 T 13-10-2018 Astex_2400 b5ca670ba894a5abbab277ac3a665a69 325 PIRSF PIRSF018266 9 324 1.5E-71 T 13-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component Astex_2400 b5ca670ba894a5abbab277ac3a665a69 325 Pfam PF16220 Domain of unknown function (DUF4880) 18 58 1.4E-10 T 13-10-2018 IPR032623 FecR, N-terminal Astex_3189 ef3e9ed6e475123be0285f88cb0214e7 331 Gene3D G3DSA:3.40.50.1370 32 319 5.7E-87 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 Astex_3189 ef3e9ed6e475123be0285f88cb0214e7 331 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 177 322 2.9E-20 T 13-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 Astex_3189 ef3e9ed6e475123be0285f88cb0214e7 331 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 276 285 6.0E-12 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Astex_3189 ef3e9ed6e475123be0285f88cb0214e7 331 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 72 91 6.0E-12 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Astex_3189 ef3e9ed6e475123be0285f88cb0214e7 331 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 156 167 6.0E-12 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Astex_3189 ef3e9ed6e475123be0285f88cb0214e7 331 PRINTS PR00101 Aspartate carbamoyltransferase signature 305 319 6.2E-29 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Astex_3189 ef3e9ed6e475123be0285f88cb0214e7 331 PRINTS PR00101 Aspartate carbamoyltransferase signature 239 248 6.2E-29 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Astex_3189 ef3e9ed6e475123be0285f88cb0214e7 331 PRINTS PR00101 Aspartate carbamoyltransferase signature 155 172 6.2E-29 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Astex_3189 ef3e9ed6e475123be0285f88cb0214e7 331 PRINTS PR00101 Aspartate carbamoyltransferase signature 280 285 6.2E-29 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Astex_3189 ef3e9ed6e475123be0285f88cb0214e7 331 PRINTS PR00101 Aspartate carbamoyltransferase signature 62 84 6.2E-29 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Astex_3189 ef3e9ed6e475123be0285f88cb0214e7 331 PRINTS PR00101 Aspartate carbamoyltransferase signature 100 109 6.2E-29 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Astex_3189 ef3e9ed6e475123be0285f88cb0214e7 331 SUPERFAMILY SSF53671 21 324 7.46E-92 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 Astex_3189 ef3e9ed6e475123be0285f88cb0214e7 331 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 26 168 8.6E-38 T 13-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 Astex_3189 ef3e9ed6e475123be0285f88cb0214e7 331 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 25 326 37.877 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Astex_3189 ef3e9ed6e475123be0285f88cb0214e7 331 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 72 79 - T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 Astex_3189 ef3e9ed6e475123be0285f88cb0214e7 331 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 27 323 3.3E-88 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Astex_3189 ef3e9ed6e475123be0285f88cb0214e7 331 Gene3D G3DSA:3.40.50.1370 156 303 5.7E-87 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 Astex_0676 88cceeab42c87c34a9cfb194af709afb 117 SUPERFAMILY SSF55620 6 116 2.33E-23 T 13-10-2018 Astex_0676 88cceeab42c87c34a9cfb194af709afb 117 Gene3D G3DSA:3.30.1130.10 2 117 2.4E-32 T 13-10-2018 Astex_0676 88cceeab42c87c34a9cfb194af709afb 117 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 7 114 2.0E-21 T 13-10-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 Astex_0676 88cceeab42c87c34a9cfb194af709afb 117 Pfam PF02152 Dihydroneopterin aldolase 8 113 4.9E-22 T 13-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 Astex_0676 88cceeab42c87c34a9cfb194af709afb 117 SMART SM00905 8 115 4.3E-25 T 13-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 Astex_0676 88cceeab42c87c34a9cfb194af709afb 117 TIGRFAM TIGR00526 folB_dom: FolB domain 7 113 7.2E-16 T 13-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 Astex_1719 9c0680c95ad258766ad44d8e1cc7dfa3 616 Gene3D G3DSA:1.20.1560.10 40 362 1.0E-77 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Astex_1719 9c0680c95ad258766ad44d8e1cc7dfa3 616 TIGRFAM TIGR02204 MsbA_rel: ABC transporter, permease/ATP-binding protein 40 614 1.1E-250 T 13-10-2018 IPR011918 ABC transporter, ATP-binding/permease protein Astex_1719 9c0680c95ad258766ad44d8e1cc7dfa3 616 Pfam PF00005 ABC transporter 395 543 6.4E-35 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_1719 9c0680c95ad258766ad44d8e1cc7dfa3 616 Pfam PF00664 ABC transporter transmembrane region 60 328 3.9E-49 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 Astex_1719 9c0680c95ad258766ad44d8e1cc7dfa3 616 SUPERFAMILY SSF52540 366 614 5.54E-87 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1719 9c0680c95ad258766ad44d8e1cc7dfa3 616 SUPERFAMILY SSF90123 46 365 2.22E-76 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Astex_1719 9c0680c95ad258766ad44d8e1cc7dfa3 616 SMART SM00382 403 589 1.3E-19 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_1719 9c0680c95ad258766ad44d8e1cc7dfa3 616 ProSitePatterns PS00211 ABC transporters family signature. 515 529 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Astex_1719 9c0680c95ad258766ad44d8e1cc7dfa3 616 Gene3D G3DSA:3.40.50.300 369 615 5.8E-94 T 13-10-2018 Astex_1750 cdf88dac4b1628379cc692037133ad21 273 SUPERFAMILY SSF50891 29 213 3.94E-31 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily Astex_1750 cdf88dac4b1628379cc692037133ad21 273 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 67 84 - T 13-10-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 Astex_1750 cdf88dac4b1628379cc692037133ad21 273 Gene3D G3DSA:2.40.100.10 13 239 1.6E-33 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily Astex_1750 cdf88dac4b1628379cc692037133ad21 273 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 34 215 2.2E-30 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 Astex_0541 70a728e4ff5e15c9a8357222b68557bd 507 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 30 124 3.2E-28 T 13-10-2018 IPR032093 Phospholipase D, N-terminal Astex_0541 70a728e4ff5e15c9a8357222b68557bd 507 Pfam PF09423 PhoD-like phosphatase 134 483 9.9E-95 T 13-10-2018 IPR018946 Alkaline phosphatase D-related Astex_0541 70a728e4ff5e15c9a8357222b68557bd 507 Gene3D G3DSA:2.60.40.380 20 126 1.7E-32 T 13-10-2018 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 Astex_0541 70a728e4ff5e15c9a8357222b68557bd 507 Gene3D G3DSA:3.60.21.70 127 507 8.6E-116 T 13-10-2018 IPR038607 PhoD-like superfamily Astex_0541 70a728e4ff5e15c9a8357222b68557bd 507 SUPERFAMILY SSF56300 133 488 1.36E-29 T 13-10-2018 Astex_2747 a0eef4dd5cb276aad1aabdca08c537b4 206 SUPERFAMILY SSF47240 5 202 2.34E-73 T 13-10-2018 IPR009078 Ferritin-like superfamily Astex_2747 a0eef4dd5cb276aad1aabdca08c537b4 206 PIRSF PIRSF020736 1 203 1.2E-80 T 13-10-2018 IPR010386 tRNA-hydroxylase MiaE GO:0006400|GO:0045301 Astex_2747 a0eef4dd5cb276aad1aabdca08c537b4 206 Pfam PF06175 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) 56 198 3.1E-55 T 13-10-2018 IPR010386 tRNA-hydroxylase MiaE GO:0006400|GO:0045301 Astex_2747 a0eef4dd5cb276aad1aabdca08c537b4 206 Gene3D G3DSA:1.20.1260.10 2 206 2.8E-78 T 13-10-2018 IPR012347 Ferritin-like Astex_1064 e3e0bfe0d33db5e32a42227e59e9d90d 375 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 77 351 3.6E-44 T 13-10-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0016788 Astex_1064 e3e0bfe0d33db5e32a42227e59e9d90d 375 PIRSF PIRSF039012 31 359 3.1E-75 T 13-10-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0016788 Astex_1064 e3e0bfe0d33db5e32a42227e59e9d90d 375 Gene3D G3DSA:3.40.630.10 39 354 1.9E-75 T 13-10-2018 Astex_1064 e3e0bfe0d33db5e32a42227e59e9d90d 375 SUPERFAMILY SSF53187 66 355 1.85E-42 T 13-10-2018 Astex_0877 fdf449d08bbf60e9cd88a2c4eed900bd 294 Gene3D G3DSA:3.60.110.10 1 290 6.8E-105 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily Astex_0877 fdf449d08bbf60e9cd88a2c4eed900bd 294 Pfam PF00795 Carbon-nitrogen hydrolase 7 267 1.7E-52 T 13-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 Astex_0877 fdf449d08bbf60e9cd88a2c4eed900bd 294 TIGRFAM TIGR03381 agmatine_aguB: N-carbamoylputrescine amidase 5 286 1.2E-138 T 13-10-2018 IPR017755 N-carbamoylputrescine amidase GO:0006596|GO:0050126 KEGG: 00330+3.5.1.53|MetaCyc: PWY-43 Astex_0877 fdf449d08bbf60e9cd88a2c4eed900bd 294 SUPERFAMILY SSF56317 3 287 6.93E-81 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily Astex_2144 e15c59b5fb4300b95934224abffc00f1 79 Pfam PF00550 Phosphopantetheine attachment site 9 74 1.3E-5 T 13-10-2018 IPR009081 Phosphopantetheine binding ACP domain Astex_2144 e15c59b5fb4300b95934224abffc00f1 79 Gene3D G3DSA:1.10.1200.10 1 78 1.0E-8 T 13-10-2018 IPR036736 ACP-like superfamily Astex_2144 e15c59b5fb4300b95934224abffc00f1 79 SUPERFAMILY SSF47336 3 76 3.17E-8 T 13-10-2018 IPR036736 ACP-like superfamily Astex_1898 8074dcc18aac671adc79f96a4ac753b8 315 Gene3D G3DSA:3.40.50.720 4 122 4.4E-37 T 13-10-2018 Astex_1898 8074dcc18aac671adc79f96a4ac753b8 315 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 10 119 1.3E-20 T 13-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 Astex_1898 8074dcc18aac671adc79f96a4ac753b8 315 SUPERFAMILY SSF51735 8 171 2.82E-42 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_1898 8074dcc18aac671adc79f96a4ac753b8 315 Gene3D G3DSA:3.30.360.10 123 315 7.1E-75 T 13-10-2018 Astex_3654 16bf0c6f3b6edd5956f9005a549d9f4b 92 Gene3D G3DSA:1.20.5.780 6 90 9.3E-23 T 13-10-2018 Astex_3654 16bf0c6f3b6edd5956f9005a549d9f4b 92 SUPERFAMILY SSF47598 9 84 1.08E-19 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 Astex_3654 16bf0c6f3b6edd5956f9005a549d9f4b 92 Pfam PF08681 Protein of unknown function (DUF1778) 11 87 7.2E-23 T 13-10-2018 IPR014795 Vibrio phage ICP1, Orf50 Astex_2282 347e3e5791cd57a3f5f913fb06ae2e65 345 Pfam PF00288 GHMP kinases N terminal domain 103 170 6.4E-15 T 13-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 Astex_2282 347e3e5791cd57a3f5f913fb06ae2e65 345 PIRSF PIRSF036406 3 344 5.3E-124 T 13-10-2018 IPR014606 D,D-heptose 7-phosphate kinase KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 Astex_2282 347e3e5791cd57a3f5f913fb06ae2e65 345 SUPERFAMILY SSF54211 4 189 4.55E-36 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Astex_2282 347e3e5791cd57a3f5f913fb06ae2e65 345 SUPERFAMILY SSF55060 190 323 1.42E-24 T 13-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily Astex_2282 347e3e5791cd57a3f5f913fb06ae2e65 345 Pfam PF08544 GHMP kinases C terminal 243 314 1.9E-8 T 13-10-2018 IPR013750 GHMP kinase, C-terminal domain Astex_2282 347e3e5791cd57a3f5f913fb06ae2e65 345 Gene3D G3DSA:3.30.230.120 2 344 1.5E-103 T 13-10-2018 Astex_2282 347e3e5791cd57a3f5f913fb06ae2e65 345 PRINTS PR00960 LmbP protein signature 108 129 1.2E-41 T 13-10-2018 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0016301 KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 Astex_2282 347e3e5791cd57a3f5f913fb06ae2e65 345 PRINTS PR00960 LmbP protein signature 9 24 1.2E-41 T 13-10-2018 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0016301 KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 Astex_2282 347e3e5791cd57a3f5f913fb06ae2e65 345 PRINTS PR00960 LmbP protein signature 286 305 1.2E-41 T 13-10-2018 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0016301 KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 Astex_2282 347e3e5791cd57a3f5f913fb06ae2e65 345 PRINTS PR00960 LmbP protein signature 258 282 1.2E-41 T 13-10-2018 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0016301 KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 Astex_2282 347e3e5791cd57a3f5f913fb06ae2e65 345 PRINTS PR00960 LmbP protein signature 150 169 1.2E-41 T 13-10-2018 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0016301 KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 Astex_3466 3b00280729b7cf6b443ea5c8f8a1a59e 181 ProSitePatterns PS00855 Signal peptidases II signature. 120 132 - T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 Astex_3466 3b00280729b7cf6b443ea5c8f8a1a59e 181 TIGRFAM TIGR00077 lspA: signal peptidase II 32 179 3.0E-33 T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 Astex_3466 3b00280729b7cf6b443ea5c8f8a1a59e 181 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 72 80 2.5E-16 T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 Astex_3466 3b00280729b7cf6b443ea5c8f8a1a59e 181 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 117 132 2.5E-16 T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 Astex_3466 3b00280729b7cf6b443ea5c8f8a1a59e 181 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 152 168 2.5E-16 T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 Astex_3466 3b00280729b7cf6b443ea5c8f8a1a59e 181 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 24 177 14.968 T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 Astex_3466 3b00280729b7cf6b443ea5c8f8a1a59e 181 Pfam PF01252 Signal peptidase (SPase) II 34 172 1.9E-36 T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 Astex_0254 bcd32557485eb369efbd5cfe362af56b 1069 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 51 1069 2.5E-176 T 13-10-2018 IPR010104 Bacterial TonB-dependent receptor Astex_0254 bcd32557485eb369efbd5cfe362af56b 1069 Gene3D G3DSA:2.170.130.10 52 182 1.8E-11 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_0254 bcd32557485eb369efbd5cfe362af56b 1069 SUPERFAMILY SSF56935 52 1069 4.58E-61 T 13-10-2018 Astex_0254 bcd32557485eb369efbd5cfe362af56b 1069 Pfam PF00593 TonB dependent receptor 441 1068 8.6E-31 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_0254 bcd32557485eb369efbd5cfe362af56b 1069 Pfam PF07715 TonB-dependent Receptor Plug Domain 69 178 2.5E-10 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_1565 73663db39c5b5fd2effaf959425a594e 254 Pfam PF01936 NYN domain 32 200 4.2E-10 T 13-10-2018 IPR021139 NYN domain, limkain-b1-type Astex_1565 73663db39c5b5fd2effaf959425a594e 254 Gene3D G3DSA:3.40.50.1010 29 208 4.7E-11 T 13-10-2018 Astex_2702 7057813a4bccf96555cdf023cd8a886a 498 Gene3D G3DSA:3.60.20.10 26 473 7.9E-155 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Astex_2702 7057813a4bccf96555cdf023cd8a886a 498 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 25 471 45.017 T 13-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 Astex_2702 7057813a4bccf96555cdf023cd8a886a 498 SUPERFAMILY SSF53271 260 481 2.42E-74 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like Astex_2702 7057813a4bccf96555cdf023cd8a886a 498 PIRSF PIRSF000485 22 487 1.6E-169 T 13-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 Astex_2702 7057813a4bccf96555cdf023cd8a886a 498 SUPERFAMILY SSF56235 26 252 1.54E-69 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Astex_2702 7057813a4bccf96555cdf023cd8a886a 498 Pfam PF13537 Glutamine amidotransferase domain 108 224 4.7E-21 T 13-10-2018 IPR017932 Glutamine amidotransferase type 2 domain Astex_2702 7057813a4bccf96555cdf023cd8a886a 498 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 26 472 4.4E-153 T 13-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 Astex_2702 7057813a4bccf96555cdf023cd8a886a 498 Gene3D G3DSA:3.40.50.2020 285 449 7.9E-155 T 13-10-2018 Astex_2601 6a4d2edc00d9afad98861c19c6249860 890 Gene3D G3DSA:3.40.50.740 71 563 1.6E-168 T 13-10-2018 Astex_2601 6a4d2edc00d9afad98861c19c6249860 890 Gene3D G3DSA:3.40.228.10 139 567 1.6E-168 T 13-10-2018 Astex_2601 6a4d2edc00d9afad98861c19c6249860 890 Gene3D G3DSA:2.40.40.20 571 703 1.1E-37 T 13-10-2018 Astex_2601 6a4d2edc00d9afad98861c19c6249860 890 Pfam PF00384 Molybdopterin oxidoreductase 59 481 9.5E-70 T 13-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2601 6a4d2edc00d9afad98861c19c6249860 890 PIRSF PIRSF036643 1 704 2.4E-133 T 13-10-2018 Astex_2601 6a4d2edc00d9afad98861c19c6249860 890 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 4 50 2.8E-14 T 13-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2601 6a4d2edc00d9afad98861c19c6249860 890 SUPERFAMILY SSF53706 4 569 1.44E-171 T 13-10-2018 Astex_2601 6a4d2edc00d9afad98861c19c6249860 890 SMART SM00926 2 55 1.9E-14 T 13-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2601 6a4d2edc00d9afad98861c19c6249860 890 Gene3D G3DSA:2.20.25.90 3 52 8.4E-13 T 13-10-2018 Astex_2601 6a4d2edc00d9afad98861c19c6249860 890 SUPERFAMILY SSF50692 555 698 2.03E-41 T 13-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily Astex_2601 6a4d2edc00d9afad98861c19c6249860 890 Pfam PF01568 Molydopterin dinucleotide binding domain 583 694 7.7E-28 T 13-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 Astex_2601 6a4d2edc00d9afad98861c19c6249860 890 Gene3D G3DSA:1.10.10.1100 825 876 1.4E-8 T 13-10-2018 Astex_2601 6a4d2edc00d9afad98861c19c6249860 890 Pfam PF04324 BFD-like [2Fe-2S] binding domain 825 872 4.1E-9 T 13-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain Astex_2749 ec9c7229387e062beac47f47a19fdafd 172 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 1 159 24.522 T 13-10-2018 IPR022973 Ribosomal protein L10 Astex_2749 ec9c7229387e062beac47f47a19fdafd 172 Gene3D G3DSA:3.30.70.1730 1 132 5.3E-33 T 13-10-2018 Astex_2749 ec9c7229387e062beac47f47a19fdafd 172 Pfam PF00466 Ribosomal protein L10 1 98 1.1E-19 T 13-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 Astex_2749 ec9c7229387e062beac47f47a19fdafd 172 SUPERFAMILY SSF160369 1 169 1.96E-49 T 13-10-2018 Astex_2749 ec9c7229387e062beac47f47a19fdafd 172 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 4 147 0.004 T 13-10-2018 Astex_1325 886d0735d589946e3fbaec0632dc8841 291 Pfam PF00248 Aldo/keto reductase family 24 287 5.3E-60 T 13-10-2018 IPR023210 NADP-dependent oxidoreductase domain Astex_1325 886d0735d589946e3fbaec0632dc8841 291 Gene3D G3DSA:3.20.20.100 17 291 1.6E-77 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily Astex_1325 886d0735d589946e3fbaec0632dc8841 291 SUPERFAMILY SSF51430 17 289 4.45E-73 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily Astex_2586 990b4878876faf82094f2afedd657f71 505 SUPERFAMILY SSF51905 6 423 1.35E-33 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_2586 990b4878876faf82094f2afedd657f71 505 Gene3D G3DSA:3.50.50.60 6 497 5.3E-185 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_2586 990b4878876faf82094f2afedd657f71 505 Pfam PF04820 Tryptophan halogenase 9 465 2.8E-177 T 13-10-2018 IPR006905 Flavin-dependent halogenase Astex_2586 990b4878876faf82094f2afedd657f71 505 PIRSF PIRSF011396 1 501 1.2E-189 T 13-10-2018 IPR033856 Flavin-dependent tryptophan halogenase Astex_3567 2ba3816581b90dfc0598d1700254ced1 302 Gene3D G3DSA:1.10.10.10 1 104 8.0E-14 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_3567 2ba3816581b90dfc0598d1700254ced1 302 SUPERFAMILY SSF53850 103 300 4.89E-29 T 13-10-2018 Astex_3567 2ba3816581b90dfc0598d1700254ced1 302 SUPERFAMILY SSF46785 11 124 1.16E-18 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_3567 2ba3816581b90dfc0598d1700254ced1 302 Pfam PF03466 LysR substrate binding domain 101 297 6.6E-24 T 13-10-2018 IPR005119 LysR, substrate-binding Astex_3567 2ba3816581b90dfc0598d1700254ced1 302 Gene3D G3DSA:3.40.190.290 105 297 5.2E-33 T 13-10-2018 Astex_3567 2ba3816581b90dfc0598d1700254ced1 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 17 75 1.9E-14 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_1582 cae9008f7e009110fb47718d593ea2eb 120 SUPERFAMILY SSF54593 2 118 1.93E-23 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Astex_1582 cae9008f7e009110fb47718d593ea2eb 120 Gene3D G3DSA:3.10.180.10 1 117 5.2E-37 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Astex_1582 cae9008f7e009110fb47718d593ea2eb 120 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 112 7.1E-7 T 13-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Astex_2934 9ab9ed1785830e3dff59ef25fc885a7c 716 Hamap MF_01129 Putative K(+)-stimulated pyrophosphate-energized sodium pump [hppA]. 2 713 24.336 T 13-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 Astex_2934 9ab9ed1785830e3dff59ef25fc885a7c 716 Pfam PF03030 Inorganic H+ pyrophosphatase 13 707 3.6E-246 T 13-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 Astex_2934 9ab9ed1785830e3dff59ef25fc885a7c 716 TIGRFAM TIGR01104 V_PPase: V-type H(+)-translocating pyrophosphatase 7 714 1.5E-257 T 13-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 Astex_2934 9ab9ed1785830e3dff59ef25fc885a7c 716 PIRSF PIRSF001265 1 716 5.0E-233 T 13-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 Astex_0144 dae5b4b73348a39630ab12221a699878 151 PIRSF PIRSF004638 1 150 2.7E-43 T 13-10-2018 IPR005265 Uncharacterised protein family UPF0093 Astex_0144 dae5b4b73348a39630ab12221a699878 151 Pfam PF03653 Uncharacterised protein family (UPF0093) 2 146 3.8E-47 T 13-10-2018 IPR005265 Uncharacterised protein family UPF0093 Astex_1179 f8b382ac57fa2093b9594ff35e17ceac 489 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 12 57 3.8E-10 T 13-10-2018 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal Astex_1179 f8b382ac57fa2093b9594ff35e17ceac 489 Pfam PF00092 von Willebrand factor type A domain 370 474 6.1E-6 T 13-10-2018 IPR002035 von Willebrand factor, type A Astex_1179 f8b382ac57fa2093b9594ff35e17ceac 489 SUPERFAMILY SSF53300 132 480 8.48E-19 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Astex_2049 54eb361bd137aa820742cd76dfdf557e 503 SUPERFAMILY SSF53720 15 490 7.72E-129 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 Astex_2049 54eb361bd137aa820742cd76dfdf557e 503 Gene3D G3DSA:3.40.605.10 22 479 7.9E-134 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 Astex_2049 54eb361bd137aa820742cd76dfdf557e 503 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 257 264 - T 13-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 Astex_2049 54eb361bd137aa820742cd76dfdf557e 503 Gene3D G3DSA:3.40.309.10 261 454 7.9E-134 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 Astex_2049 54eb361bd137aa820742cd76dfdf557e 503 Pfam PF00171 Aldehyde dehydrogenase family 21 482 3.9E-124 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 Astex_2433 592241c1c93e95876218f157cac9746c 93 Pfam PF01381 Helix-turn-helix 13 66 9.4E-12 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Astex_2433 592241c1c93e95876218f157cac9746c 93 SUPERFAMILY SSF47413 4 71 3.1E-15 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Astex_2433 592241c1c93e95876218f157cac9746c 93 SMART SM00530 10 66 2.7E-10 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Astex_2433 592241c1c93e95876218f157cac9746c 93 Gene3D G3DSA:1.10.260.40 1 71 5.2E-18 T 13-10-2018 Astex_2671 c8fb24373fb1466046e4d5d4926f8881 234 SUPERFAMILY SSF54427 91 226 3.37E-28 T 13-10-2018 IPR032710 NTF2-like domain superfamily Astex_2671 c8fb24373fb1466046e4d5d4926f8881 234 Pfam PF04335 VirB8 protein 21 223 4.0E-63 T 13-10-2018 IPR007430 Bacterial virulence protein VirB8 GO:0016020 Astex_2671 c8fb24373fb1466046e4d5d4926f8881 234 Gene3D G3DSA:3.10.450.230 121 224 4.6E-6 T 13-10-2018 Astex_1790 12446005207db60c4c619598095bc936 119 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_1790 12446005207db60c4c619598095bc936 119 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 113 2.6E-45 T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_1790 12446005207db60c4c619598095bc936 119 Gene3D G3DSA:1.10.720.90 2 55 1.7E-23 T 13-10-2018 Astex_1790 12446005207db60c4c619598095bc936 119 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 70 1.0E-18 T 13-10-2018 Astex_1790 12446005207db60c4c619598095bc936 119 SUPERFAMILY SSF74731 3 117 2.09E-45 T 13-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_1790 12446005207db60c4c619598095bc936 119 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 27.76 T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_1790 12446005207db60c4c619598095bc936 119 Pfam PF00453 Ribosomal protein L20 3 108 7.9E-46 T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_1790 12446005207db60c4c619598095bc936 119 Gene3D G3DSA:1.10.1900.20 56 119 4.4E-26 T 13-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_1790 12446005207db60c4c619598095bc936 119 PRINTS PR00062 Ribosomal protein L20 signature 12 41 7.1E-34 T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_1790 12446005207db60c4c619598095bc936 119 PRINTS PR00062 Ribosomal protein L20 signature 42 71 7.1E-34 T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_1790 12446005207db60c4c619598095bc936 119 PRINTS PR00062 Ribosomal protein L20 signature 75 101 7.1E-34 T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_2281 49530cdce4f05b0bcf09d3ca9a5c35be 1138 SUPERFAMILY SSF53756 791 1119 2.32E-22 T 13-10-2018 Astex_2281 49530cdce4f05b0bcf09d3ca9a5c35be 1138 Pfam PF00535 Glycosyl transferase family 2 511 638 6.6E-25 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 Astex_2281 49530cdce4f05b0bcf09d3ca9a5c35be 1138 Gene3D G3DSA:3.90.550.10 493 731 9.3E-48 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_2281 49530cdce4f05b0bcf09d3ca9a5c35be 1138 SUPERFAMILY SSF53448 504 751 6.19E-50 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_2281 49530cdce4f05b0bcf09d3ca9a5c35be 1138 Gene3D G3DSA:3.40.50.2000 959 1116 1.7E-18 T 13-10-2018 Astex_2281 49530cdce4f05b0bcf09d3ca9a5c35be 1138 Pfam PF13692 Glycosyl transferases group 1 963 1100 3.9E-26 T 13-10-2018 Astex_2915 cf6eb3874ea32b644ddcbc00efa89a15 691 Gene3D G3DSA:2.40.170.20 192 689 6.5E-72 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_2915 cf6eb3874ea32b644ddcbc00efa89a15 691 SUPERFAMILY SSF56935 27 688 1.17E-94 T 13-10-2018 Astex_2915 cf6eb3874ea32b644ddcbc00efa89a15 691 Gene3D G3DSA:2.170.130.10 51 175 7.1E-16 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_2915 cf6eb3874ea32b644ddcbc00efa89a15 691 Pfam PF07715 TonB-dependent Receptor Plug Domain 59 168 1.0E-12 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_2915 cf6eb3874ea32b644ddcbc00efa89a15 691 Pfam PF00593 TonB dependent receptor 266 688 2.6E-40 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_0844 78b0c2c2a22509c917414cccb032f55a 248 PIRSF PIRSF005457 1 248 4.1E-82 T 13-10-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 Astex_0844 78b0c2c2a22509c917414cccb032f55a 248 Pfam PF16123 Hydroxyacylglutathione hydrolase C-terminus 172 248 3.7E-16 T 13-10-2018 IPR032282 Hydroxyacylglutathione hydrolase, C-terminal domain KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 Astex_0844 78b0c2c2a22509c917414cccb032f55a 248 TIGRFAM TIGR03413 GSH_gloB: hydroxyacylglutathione hydrolase 6 248 1.2E-77 T 13-10-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 Astex_0844 78b0c2c2a22509c917414cccb032f55a 248 Hamap MF_01374 Hydroxyacylglutathione hydrolase [gloB]. 4 248 35.507 T 13-10-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 Astex_0844 78b0c2c2a22509c917414cccb032f55a 248 Pfam PF00753 Metallo-beta-lactamase superfamily 42 171 2.1E-15 T 13-10-2018 IPR001279 Metallo-beta-lactamase Astex_0844 78b0c2c2a22509c917414cccb032f55a 248 SUPERFAMILY SSF56281 4 227 2.84E-60 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Astex_0844 78b0c2c2a22509c917414cccb032f55a 248 SMART SM00849 14 171 6.0E-31 T 13-10-2018 IPR001279 Metallo-beta-lactamase Astex_0844 78b0c2c2a22509c917414cccb032f55a 248 Gene3D G3DSA:3.60.15.10 4 248 1.2E-68 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Astex_1233 1ca3cfedeb1438a6f05f12b3b9a8d83a 500 Pfam PF13520 Amino acid permease 56 470 6.7E-50 T 13-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 Astex_1233 1ca3cfedeb1438a6f05f12b3b9a8d83a 500 PIRSF PIRSF006060 43 500 2.8E-82 T 13-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 Astex_1233 1ca3cfedeb1438a6f05f12b3b9a8d83a 500 Gene3D G3DSA:1.20.1740.10 51 499 2.8E-111 T 13-10-2018 Astex_2594 83600b71ff22faccd3ec827e98221b11 612 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 309 579 3.2E-29 T 13-10-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 Astex_2594 83600b71ff22faccd3ec827e98221b11 612 Gene3D G3DSA:3.20.20.80 309 611 1.8E-66 T 13-10-2018 Astex_2594 83600b71ff22faccd3ec827e98221b11 612 SUPERFAMILY SSF49785 32 214 1.46E-38 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_2594 83600b71ff22faccd3ec827e98221b11 612 PRINTS PR00132 Glycosyl hydrolase family 2 signature 418 433 1.4E-10 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_2594 83600b71ff22faccd3ec827e98221b11 612 PRINTS PR00132 Glycosyl hydrolase family 2 signature 513 528 1.4E-10 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_2594 83600b71ff22faccd3ec827e98221b11 612 PRINTS PR00132 Glycosyl hydrolase family 2 signature 318 332 1.4E-10 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_2594 83600b71ff22faccd3ec827e98221b11 612 PRINTS PR00132 Glycosyl hydrolase family 2 signature 140 155 1.4E-10 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_2594 83600b71ff22faccd3ec827e98221b11 612 Pfam PF00703 Glycosyl hydrolases family 2 236 307 4.0E-5 T 13-10-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_2594 83600b71ff22faccd3ec827e98221b11 612 SUPERFAMILY SSF49303 217 308 5.25E-10 T 13-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily Astex_2594 83600b71ff22faccd3ec827e98221b11 612 SUPERFAMILY SSF51445 304 608 9.0E-59 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_2594 83600b71ff22faccd3ec827e98221b11 612 ProSitePatterns PS00608 Glycosyl hydrolases family 2 acid/base catalyst. 418 432 - T 13-10-2018 IPR023232 Glycoside hydrolase, family 2, active site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_2594 83600b71ff22faccd3ec827e98221b11 612 Gene3D G3DSA:2.60.120.260 28 214 1.3E-37 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_2594 83600b71ff22faccd3ec827e98221b11 612 Gene3D G3DSA:2.60.40.10 218 307 1.7E-8 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_2594 83600b71ff22faccd3ec827e98221b11 612 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 87 214 2.9E-17 T 13-10-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_1804 e94c9205b8fe6f8a1b595af9520911a4 106 Gene3D G3DSA:1.10.238.10 71 96 5.6E-6 T 13-10-2018 Astex_1804 e94c9205b8fe6f8a1b595af9520911a4 106 Pfam PF13202 EF hand 49 66 0.0013 T 13-10-2018 IPR002048 EF-hand domain GO:0005509 Astex_1804 e94c9205b8fe6f8a1b595af9520911a4 106 Pfam PF13202 EF hand 73 91 9.8E-6 T 13-10-2018 IPR002048 EF-hand domain GO:0005509 Astex_1804 e94c9205b8fe6f8a1b595af9520911a4 106 ProSitePatterns PS00018 EF-hand calcium-binding domain. 78 90 - T 13-10-2018 IPR018247 EF-Hand 1, calcium-binding site Astex_1804 e94c9205b8fe6f8a1b595af9520911a4 106 Gene3D G3DSA:1.10.238.10 9 70 6.3E-6 T 13-10-2018 Astex_1804 e94c9205b8fe6f8a1b595af9520911a4 106 SUPERFAMILY SSF47473 37 94 3.25E-11 T 13-10-2018 IPR011992 EF-hand domain pair Astex_1871 2386cb382a8493764a233c05580b9da5 271 Pfam PF04654 Protein of unknown function, DUF599 16 221 1.1E-42 T 13-10-2018 IPR006747 Protein of unknown function DUF599 Astex_2549 1fee44d37ca37147b4dcb64b9bb06265 139 Pfam PF08818 Domain of unknown function (DU1801) 26 128 4.4E-9 T 13-10-2018 IPR014922 Domain of unknown function DUF1801 Astex_3605 c2272fc6d0722aa2f587efba29f0746b 924 Gene3D G3DSA:3.20.20.520 173 468 7.2E-113 T 13-10-2018 Astex_3605 c2272fc6d0722aa2f587efba29f0746b 924 Gene3D G3DSA:3.30.379.10 14 172 7.3E-33 T 13-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 Astex_3605 c2272fc6d0722aa2f587efba29f0746b 924 SUPERFAMILY SSF55545 30 143 1.81E-5 T 13-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 Astex_3605 c2272fc6d0722aa2f587efba29f0746b 924 Gene3D G3DSA:2.60.120.1620 758 923 2.5E-20 T 13-10-2018 Astex_3605 c2272fc6d0722aa2f587efba29f0746b 924 Pfam PF15979 Glycosyl hydrolase family 115 169 509 1.8E-126 T 13-10-2018 IPR031924 Glycosyl hydrolase family 115 Astex_3605 c2272fc6d0722aa2f587efba29f0746b 924 Gene3D G3DSA:1.20.58.2150 469 637 2.9E-34 T 13-10-2018 Astex_1254 5147338b7d2021ae46698c40c7f5a8c3 173 Gene3D G3DSA:2.40.160.20 24 173 2.1E-15 T 13-10-2018 Astex_1254 5147338b7d2021ae46698c40c7f5a8c3 173 SUPERFAMILY SSF56925 32 173 3.92E-15 T 13-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel Astex_1254 5147338b7d2021ae46698c40c7f5a8c3 173 Pfam PF13505 Outer membrane protein beta-barrel domain 10 173 6.6E-19 T 13-10-2018 IPR027385 Outer membrane protein beta-barrel Astex_2224 1289f6cbbe887c02cff703ec6ed098fa 355 Gene3D G3DSA:1.10.101.10 288 349 4.2E-5 T 13-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 Astex_2224 1289f6cbbe887c02cff703ec6ed098fa 355 Pfam PF01471 Putative peptidoglycan binding domain 300 344 5.4E-6 T 13-10-2018 IPR002477 Peptidoglycan binding-like Astex_2224 1289f6cbbe887c02cff703ec6ed098fa 355 SUPERFAMILY SSF47090 291 347 2.88E-8 T 13-10-2018 IPR036365 PGBD-like superfamily Astex_3209 32fb0649a4a745fb6aed69bb6a47a5d9 441 Gene3D G3DSA:3.20.20.80 57 356 3.7E-107 T 13-10-2018 Astex_3209 32fb0649a4a745fb6aed69bb6a47a5d9 441 Pfam PF01120 Alpha-L-fucosidase 56 352 7.8E-79 T 13-10-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 Astex_3209 32fb0649a4a745fb6aed69bb6a47a5d9 441 SMART SM00812 48 396 2.4E-90 T 13-10-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 Astex_3209 32fb0649a4a745fb6aed69bb6a47a5d9 441 PRINTS PR00741 Glycosyl hydrolase family 29 signature 207 223 9.7E-17 T 13-10-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 Astex_3209 32fb0649a4a745fb6aed69bb6a47a5d9 441 PRINTS PR00741 Glycosyl hydrolase family 29 signature 120 136 9.7E-17 T 13-10-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 Astex_3209 32fb0649a4a745fb6aed69bb6a47a5d9 441 PRINTS PR00741 Glycosyl hydrolase family 29 signature 306 327 9.7E-17 T 13-10-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 Astex_3209 32fb0649a4a745fb6aed69bb6a47a5d9 441 PRINTS PR00741 Glycosyl hydrolase family 29 signature 167 186 9.7E-17 T 13-10-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 Astex_3209 32fb0649a4a745fb6aed69bb6a47a5d9 441 PRINTS PR00741 Glycosyl hydrolase family 29 signature 339 361 9.7E-17 T 13-10-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 Astex_3209 32fb0649a4a745fb6aed69bb6a47a5d9 441 Gene3D G3DSA:2.60.40.1180 357 424 3.7E-107 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta Astex_3209 32fb0649a4a745fb6aed69bb6a47a5d9 441 PIRSF PIRSF001092 14 429 2.9E-108 T 13-10-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 Astex_3209 32fb0649a4a745fb6aed69bb6a47a5d9 441 SUPERFAMILY SSF51445 46 354 1.68E-82 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_2492 f636cdf4a8c69f0b32a1843886d1cd6d 212 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 44 201 2.9E-62 T 13-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 Astex_2492 f636cdf4a8c69f0b32a1843886d1cd6d 212 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 43 207 38.234 T 13-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 Astex_2492 f636cdf4a8c69f0b32a1843886d1cd6d 212 Gene3D G3DSA:3.30.1060.10 3 212 8.5E-90 T 13-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 Astex_2492 f636cdf4a8c69f0b32a1843886d1cd6d 212 SUPERFAMILY SSF55068 5 211 2.75E-77 T 13-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 Astex_2492 f636cdf4a8c69f0b32a1843886d1cd6d 212 Pfam PF01625 Peptide methionine sulfoxide reductase 45 201 1.1E-62 T 13-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 Astex_1776 4bd09cef5d126a99b1db1183686d414d 79 Gene3D G3DSA:2.30.30.320 8 79 7.8E-25 T 13-10-2018 IPR037135 DUF1653-like domain superfamily Astex_1776 4bd09cef5d126a99b1db1183686d414d 79 Pfam PF07866 Protein of unknown function (DUF1653) 16 77 8.6E-22 T 13-10-2018 IPR023387 DUF1653-like domain Astex_0041 3b9f0b716b5772de895d0ed47db96b21 652 Gene3D G3DSA:3.40.50.300 5 240 1.7E-69 T 13-10-2018 Astex_0041 3b9f0b716b5772de895d0ed47db96b21 652 Pfam PF12704 MacB-like periplasmic core domain 276 495 1.8E-38 T 13-10-2018 IPR025857 MacB-like periplasmic core domain Astex_0041 3b9f0b716b5772de895d0ed47db96b21 652 Pfam PF02687 FtsX-like permease family 557 645 1.4E-10 T 13-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 Astex_0041 3b9f0b716b5772de895d0ed47db96b21 652 Pfam PF00005 ABC transporter 26 174 2.1E-28 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_0041 3b9f0b716b5772de895d0ed47db96b21 652 SUPERFAMILY SSF52540 6 227 1.89E-66 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0041 3b9f0b716b5772de895d0ed47db96b21 652 SMART SM00382 35 229 3.0E-15 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_0041 3b9f0b716b5772de895d0ed47db96b21 652 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Astex_3101 10b0341f5199f8a635e26c9bda7d1a88 918 Gene3D G3DSA:1.10.268.10 376 491 6.2E-215 T 13-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 Astex_3101 10b0341f5199f8a635e26c9bda7d1a88 918 Gene3D G3DSA:2.120.10.90 765 899 4.5E-28 T 13-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal Astex_3101 10b0341f5199f8a635e26c9bda7d1a88 918 Gene3D G3DSA:2.120.10.90 529 764 1.4E-74 T 13-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal Astex_3101 10b0341f5199f8a635e26c9bda7d1a88 918 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 802 848 3.8E-10 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Astex_3101 10b0341f5199f8a635e26c9bda7d1a88 918 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 852 896 6.7E-12 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Astex_3101 10b0341f5199f8a635e26c9bda7d1a88 918 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 693 740 1.9E-10 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Astex_3101 10b0341f5199f8a635e26c9bda7d1a88 918 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 589 633 0.13 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Astex_3101 10b0341f5199f8a635e26c9bda7d1a88 918 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 536 581 2.7E-14 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Astex_3101 10b0341f5199f8a635e26c9bda7d1a88 918 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 646 689 5.3E-7 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 Astex_3101 10b0341f5199f8a635e26c9bda7d1a88 918 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 15 898 0.0 T 13-10-2018 Astex_3101 10b0341f5199f8a635e26c9bda7d1a88 918 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 39 504 5.8E-147 T 13-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Astex_3101 10b0341f5199f8a635e26c9bda7d1a88 918 SUPERFAMILY SSF56719 37 519 2.22E-171 T 13-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 Astex_3101 10b0341f5199f8a635e26c9bda7d1a88 918 SMART SM00434 18 497 1.2E-271 T 13-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 Astex_3101 10b0341f5199f8a635e26c9bda7d1a88 918 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 3 899 23.363 T 13-10-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 Astex_3101 10b0341f5199f8a635e26c9bda7d1a88 918 SUPERFAMILY SSF101904 531 907 8.76E-94 T 13-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal Astex_3101 10b0341f5199f8a635e26c9bda7d1a88 918 Gene3D G3DSA:3.30.1360.40 243 339 6.2E-215 T 13-10-2018 Astex_3101 10b0341f5199f8a635e26c9bda7d1a88 918 Gene3D G3DSA:3.90.199.10 40 518 6.2E-215 T 13-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 Astex_3132 2750c317abd4ce10b6a83a91e1f05ffc 420 SUPERFAMILY SSF53448 40 213 1.88E-33 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_3132 2750c317abd4ce10b6a83a91e1f05ffc 420 Pfam PF04138 GtrA-like protein 283 413 8.2E-14 T 13-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 Astex_3132 2750c317abd4ce10b6a83a91e1f05ffc 420 Pfam PF00535 Glycosyl transferase family 2 48 211 3.8E-26 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 Astex_3132 2750c317abd4ce10b6a83a91e1f05ffc 420 Gene3D G3DSA:3.90.550.10 26 271 6.3E-37 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_1419 358b8725c0f62694f075ac935922ba68 102 Hamap MF_00724 Flagellar hook-basal body complex protein FliE [fliE]. 8 102 13.403 T 13-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 Astex_1419 358b8725c0f62694f075ac935922ba68 102 Pfam PF02049 Flagellar hook-basal body complex protein FliE 25 102 4.2E-19 T 13-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 Astex_1419 358b8725c0f62694f075ac935922ba68 102 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 33 49 1.4E-5 T 13-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 Astex_1419 358b8725c0f62694f075ac935922ba68 102 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 66 82 1.4E-5 T 13-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 Astex_1419 358b8725c0f62694f075ac935922ba68 102 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 87 100 1.4E-5 T 13-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 Astex_3024 c6d3c5d514505f2a43b2e166a20345f8 633 SUPERFAMILY SSF52540 2 236 9.16E-40 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_3024 c6d3c5d514505f2a43b2e166a20345f8 633 SUPERFAMILY SSF52540 296 514 5.33E-45 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_3024 c6d3c5d514505f2a43b2e166a20345f8 633 Pfam PF16326 ABC transporter C-terminal domain 559 619 1.2E-8 T 13-10-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 Astex_3024 c6d3c5d514505f2a43b2e166a20345f8 633 Gene3D G3DSA:3.40.50.300 272 537 5.1E-53 T 13-10-2018 Astex_3024 c6d3c5d514505f2a43b2e166a20345f8 633 Gene3D G3DSA:3.40.50.300 1 255 3.1E-53 T 13-10-2018 Astex_3024 c6d3c5d514505f2a43b2e166a20345f8 633 Pfam PF00005 ABC transporter 18 174 8.6E-22 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_3024 c6d3c5d514505f2a43b2e166a20345f8 633 Pfam PF00005 ABC transporter 325 456 2.7E-17 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_3024 c6d3c5d514505f2a43b2e166a20345f8 633 Pfam PF12848 ABC transporter 213 290 5.2E-23 T 13-10-2018 IPR032781 ABC-transporter extension domain Astex_3024 c6d3c5d514505f2a43b2e166a20345f8 633 SMART SM00382 334 501 1.1E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_3024 c6d3c5d514505f2a43b2e166a20345f8 633 SMART SM00382 26 219 5.6E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_3024 c6d3c5d514505f2a43b2e166a20345f8 633 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Astex_0686 1ce937da20d284cb39ad2dc59046eaee 110 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 13 99 9.9E-28 T 13-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 Astex_0686 1ce937da20d284cb39ad2dc59046eaee 110 Gene3D G3DSA:3.30.1360.20 8 106 4.0E-33 T 13-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 Astex_0686 1ce937da20d284cb39ad2dc59046eaee 110 SUPERFAMILY SSF55248 10 101 7.59E-29 T 13-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 Astex_0686 1ce937da20d284cb39ad2dc59046eaee 110 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 8 101 21.582 T 13-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 Astex_3537 f568b3ebfa72df765750c59f06de6e6e 368 Gene3D G3DSA:3.40.50.2300 188 317 8.5E-59 T 13-10-2018 Astex_3537 f568b3ebfa72df765750c59f06de6e6e 368 SUPERFAMILY SSF47413 30 81 5.38E-14 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Astex_3537 f568b3ebfa72df765750c59f06de6e6e 368 Pfam PF00356 Bacterial regulatory proteins, lacI family 30 74 3.3E-15 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Astex_3537 f568b3ebfa72df765750c59f06de6e6e 368 Gene3D G3DSA:1.10.260.40 27 80 1.7E-19 T 13-10-2018 Astex_3537 f568b3ebfa72df765750c59f06de6e6e 368 Pfam PF13377 Periplasmic binding protein-like domain 197 358 1.6E-31 T 13-10-2018 Astex_3537 f568b3ebfa72df765750c59f06de6e6e 368 Gene3D G3DSA:3.40.50.2300 81 332 8.5E-59 T 13-10-2018 Astex_3537 f568b3ebfa72df765750c59f06de6e6e 368 ProSitePatterns PS00356 LacI-type HTH domain signature. 31 49 - T 13-10-2018 Astex_3537 f568b3ebfa72df765750c59f06de6e6e 368 SMART SM00354 28 97 3.0E-20 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Astex_3537 f568b3ebfa72df765750c59f06de6e6e 368 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 30 40 1.8E-5 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Astex_3537 f568b3ebfa72df765750c59f06de6e6e 368 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 40 50 1.8E-5 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Astex_3537 f568b3ebfa72df765750c59f06de6e6e 368 SUPERFAMILY SSF53822 88 362 1.12E-55 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Astex_2578 31050ea16ef57b3808e52b188f27bba8 247 Gene3D G3DSA:3.30.110.170 46 244 2.7E-57 T 13-10-2018 Astex_2578 31050ea16ef57b3808e52b188f27bba8 247 Pfam PF04402 Protein of unknown function (DUF541) 44 244 1.7E-47 T 13-10-2018 IPR007497 Protein of unknown function DUF541 Astex_2578 31050ea16ef57b3808e52b188f27bba8 247 Gene3D G3DSA:3.30.70.2970 55 163 2.7E-57 T 13-10-2018 Astex_1028 b1a3202b96f2f8d768d07560ee04fcb1 164 Gene3D G3DSA:2.40.50.870 38 155 4.2E-7 T 13-10-2018 Astex_1028 b1a3202b96f2f8d768d07560ee04fcb1 164 Pfam PF11736 Protein of unknown function (DUF3299) 65 143 3.3E-6 T 13-10-2018 IPR021727 Protein of unknown function DUF3299 Astex_1993 df638cc069ec4906c861d93953e07f78 260 SMART SM00448 134 250 8.1E-17 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1993 df638cc069ec4906c861d93953e07f78 260 SMART SM00448 4 120 0.0016 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1993 df638cc069ec4906c861d93953e07f78 260 Gene3D G3DSA:3.40.50.2300 133 258 2.7E-23 T 13-10-2018 Astex_1993 df638cc069ec4906c861d93953e07f78 260 SUPERFAMILY SSF52172 3 125 4.7E-16 T 13-10-2018 IPR011006 CheY-like superfamily Astex_1993 df638cc069ec4906c861d93953e07f78 260 Pfam PF00072 Response regulator receiver domain 7 118 2.0E-10 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1993 df638cc069ec4906c861d93953e07f78 260 Pfam PF00072 Response regulator receiver domain 136 248 1.2E-18 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1993 df638cc069ec4906c861d93953e07f78 260 Gene3D G3DSA:3.40.50.2300 3 132 5.1E-17 T 13-10-2018 Astex_1993 df638cc069ec4906c861d93953e07f78 260 SUPERFAMILY SSF52172 132 255 1.71E-24 T 13-10-2018 IPR011006 CheY-like superfamily Astex_1606 ac27ea02c37f226a2fe4783ffd7687a5 639 SMART SM00278 583 602 4.2 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 Astex_1606 ac27ea02c37f226a2fe4783ffd7687a5 639 SMART SM00278 615 634 0.055 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 Astex_1606 ac27ea02c37f226a2fe4783ffd7687a5 639 Hamap MF_00203 UvrABC system protein C [uvrC]. 22 634 25.137 T 13-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 Astex_1606 ac27ea02c37f226a2fe4783ffd7687a5 639 Pfam PF14520 Helix-hairpin-helix domain 585 632 9.8E-7 T 13-10-2018 Astex_1606 ac27ea02c37f226a2fe4783ffd7687a5 639 Gene3D G3DSA:1.10.150.20 583 636 2.3E-17 T 13-10-2018 Astex_1606 ac27ea02c37f226a2fe4783ffd7687a5 639 Pfam PF01541 GIY-YIG catalytic domain 36 111 2.9E-9 T 13-10-2018 IPR000305 GIY-YIG endonuclease Astex_1606 ac27ea02c37f226a2fe4783ffd7687a5 639 SUPERFAMILY SSF47781 548 636 4.13E-19 T 13-10-2018 IPR010994 RuvA domain 2-like Astex_1606 ac27ea02c37f226a2fe4783ffd7687a5 639 SUPERFAMILY SSF82771 34 118 1.19E-19 T 13-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 Astex_1606 ac27ea02c37f226a2fe4783ffd7687a5 639 Gene3D G3DSA:3.40.1440.10 25 120 2.9E-26 T 13-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 Astex_1606 ac27ea02c37f226a2fe4783ffd7687a5 639 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 404 569 1.4E-48 T 13-10-2018 IPR001162 UvrC family homology region Astex_1606 ac27ea02c37f226a2fe4783ffd7687a5 639 SUPERFAMILY SSF46600 209 257 1.31E-11 T 13-10-2018 IPR036876 UVR domain superfamily Astex_1606 ac27ea02c37f226a2fe4783ffd7687a5 639 Gene3D G3DSA:3.30.420.340 397 578 5.7E-46 T 13-10-2018 IPR038476 UvrC homology region 2 superfamily Astex_1606 ac27ea02c37f226a2fe4783ffd7687a5 639 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 32 614 5.6E-146 T 13-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 Astex_1606 ac27ea02c37f226a2fe4783ffd7687a5 639 Pfam PF02151 UvrB/uvrC motif 224 254 1.6E-7 T 13-10-2018 IPR001943 UVR domain GO:0005515 Astex_1606 ac27ea02c37f226a2fe4783ffd7687a5 639 SMART SM00465 35 116 3.4E-17 T 13-10-2018 IPR000305 GIY-YIG endonuclease Astex_1511 2fe0bb0b9ce90460aaee77dab394d947 567 SMART SM00283 308 562 5.4E-30 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_1511 2fe0bb0b9ce90460aaee77dab394d947 567 Pfam PF17201 Cache 3/Cache 2 fusion domain 41 191 1.4E-29 T 13-10-2018 IPR033462 Cache 3/Cache 2 fusion domain Astex_1511 2fe0bb0b9ce90460aaee77dab394d947 567 Pfam PF00672 HAMP domain 225 268 2.3E-6 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Astex_1511 2fe0bb0b9ce90460aaee77dab394d947 567 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 376 486 3.0E-27 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_1511 2fe0bb0b9ce90460aaee77dab394d947 567 Gene3D G3DSA:1.10.287.950 288 556 8.8E-48 T 13-10-2018 Astex_1511 2fe0bb0b9ce90460aaee77dab394d947 567 SMART SM00304 219 272 4.5E-6 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Astex_1511 2fe0bb0b9ce90460aaee77dab394d947 567 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 435 464 3.7E-19 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_1511 2fe0bb0b9ce90460aaee77dab394d947 567 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 325 354 3.7E-19 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_1511 2fe0bb0b9ce90460aaee77dab394d947 567 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 406 433 3.7E-19 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_1511 2fe0bb0b9ce90460aaee77dab394d947 567 SUPERFAMILY SSF58104 314 561 8.5E-48 T 13-10-2018 Astex_1511 2fe0bb0b9ce90460aaee77dab394d947 567 Gene3D G3DSA:1.20.1480.50 183 278 1.6E-8 T 13-10-2018 Astex_1511 2fe0bb0b9ce90460aaee77dab394d947 567 SUPERFAMILY SSF158472 225 268 1.44E-5 T 13-10-2018 Astex_1511 2fe0bb0b9ce90460aaee77dab394d947 567 SUPERFAMILY SSF103190 113 183 5.89E-8 T 13-10-2018 IPR029151 Periplasmic sensor-like domain superfamily Astex_2142 1e84f11c69193d1468384068118397f5 243 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 242 7.1E-55 T 13-10-2018 Astex_2142 1e84f11c69193d1468384068118397f5 243 Gene3D G3DSA:3.40.50.720 2 243 2.8E-70 T 13-10-2018 Astex_2142 1e84f11c69193d1468384068118397f5 243 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 182 8.6E-4 T 13-10-2018 Astex_2142 1e84f11c69193d1468384068118397f5 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 6.0E-9 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2142 1e84f11c69193d1468384068118397f5 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 6.0E-9 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2142 1e84f11c69193d1468384068118397f5 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 6.0E-9 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2142 1e84f11c69193d1468384068118397f5 243 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Astex_2142 1e84f11c69193d1468384068118397f5 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 6.6E-30 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2142 1e84f11c69193d1468384068118397f5 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 6.6E-30 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2142 1e84f11c69193d1468384068118397f5 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 6.6E-30 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2142 1e84f11c69193d1468384068118397f5 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 6.6E-30 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2142 1e84f11c69193d1468384068118397f5 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 6.6E-30 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2142 1e84f11c69193d1468384068118397f5 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 6.6E-30 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2142 1e84f11c69193d1468384068118397f5 243 SUPERFAMILY SSF51735 3 242 3.13E-69 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_3294 ae5f5478292a50117d156f6d72beaa17 381 SUPERFAMILY SSF74650 26 369 1.0E-98 T 13-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 Astex_3294 ae5f5478292a50117d156f6d72beaa17 381 ProSitePatterns PS00545 Aldose 1-epimerase putative active site. 195 204 - T 13-10-2018 IPR018052 Aldose 1-epimerase, conserved site KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 Astex_3294 ae5f5478292a50117d156f6d72beaa17 381 Pfam PF01263 Aldose 1-epimerase 40 367 1.1E-78 T 13-10-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 Astex_3294 ae5f5478292a50117d156f6d72beaa17 381 Gene3D G3DSA:2.70.98.10 18 371 1.4E-112 T 13-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 Astex_3294 ae5f5478292a50117d156f6d72beaa17 381 PIRSF PIRSF005096 21 372 1.9E-113 T 13-10-2018 IPR015443 Aldose 1-epimerase GO:0016853|GO:0019318 KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 Astex_1230 51c9458561dfa04e3b1f3764c84a87df 340 Pfam PF13621 Cupin-like domain 24 258 1.1E-51 T 13-10-2018 Astex_1230 51c9458561dfa04e3b1f3764c84a87df 340 SUPERFAMILY SSF51197 8 299 2.33E-48 T 13-10-2018 Astex_1230 51c9458561dfa04e3b1f3764c84a87df 340 SMART SM00558 79 271 5.8E-7 T 13-10-2018 IPR003347 JmjC domain Astex_1230 51c9458561dfa04e3b1f3764c84a87df 340 Gene3D G3DSA:2.60.120.1660 3 271 2.8E-47 T 13-10-2018 Astex_2665 c9f1af0276f4d7aba5a15641ba71c18d 328 TIGRFAM TIGR02782 TrbB_P: P-type conjugative transfer ATPase TrbB 11 319 5.4E-119 T 13-10-2018 IPR014149 Conjugative transfer, TrbB GO:0000746|GO:0005737 Astex_2665 c9f1af0276f4d7aba5a15641ba71c18d 328 Gene3D G3DSA:3.30.450.90 17 123 1.2E-14 T 13-10-2018 Astex_2665 c9f1af0276f4d7aba5a15641ba71c18d 328 SUPERFAMILY SSF52540 6 304 2.99E-40 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2665 c9f1af0276f4d7aba5a15641ba71c18d 328 Pfam PF00437 Type II/IV secretion system protein 22 291 9.7E-84 T 13-10-2018 IPR001482 Type II/IV secretion system protein Astex_2665 c9f1af0276f4d7aba5a15641ba71c18d 328 Gene3D G3DSA:3.40.50.300 124 324 2.7E-56 T 13-10-2018 Astex_0895 d0869fc3500b0df3bed79503dbe9b691 425 SUPERFAMILY SSF103473 30 420 3.4E-34 T 13-10-2018 IPR036259 MFS transporter superfamily Astex_0895 d0869fc3500b0df3bed79503dbe9b691 425 Gene3D G3DSA:1.20.1250.20 28 412 5.6E-26 T 13-10-2018 Astex_0895 d0869fc3500b0df3bed79503dbe9b691 425 Pfam PF05977 Transmembrane secretion effector 21 412 1.1E-33 T 13-10-2018 IPR010290 Transmembrane secretion effector Astex_2428 48762b76bdfd1548606beda61985de09 210 SUPERFAMILY SSF55729 1 178 4.66E-28 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Astex_2428 48762b76bdfd1548606beda61985de09 210 Gene3D G3DSA:3.40.630.30 4 186 7.2E-39 T 13-10-2018 Astex_2428 48762b76bdfd1548606beda61985de09 210 Pfam PF00765 Autoinducer synthase 20 171 1.6E-27 T 13-10-2018 IPR001690 Autoinducer synthase GO:0016740 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 Astex_2428 48762b76bdfd1548606beda61985de09 210 PRINTS PR01549 Autoinducer synthesis protein signature 19 38 2.2E-14 T 13-10-2018 IPR001690 Autoinducer synthase GO:0016740 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 Astex_2428 48762b76bdfd1548606beda61985de09 210 PRINTS PR01549 Autoinducer synthesis protein signature 96 108 2.2E-14 T 13-10-2018 IPR001690 Autoinducer synthase GO:0016740 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 Astex_2428 48762b76bdfd1548606beda61985de09 210 PRINTS PR01549 Autoinducer synthesis protein signature 141 162 2.2E-14 T 13-10-2018 IPR001690 Autoinducer synthase GO:0016740 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 Astex_2428 48762b76bdfd1548606beda61985de09 210 PRINTS PR01549 Autoinducer synthesis protein signature 63 81 2.2E-14 T 13-10-2018 IPR001690 Autoinducer synthase GO:0016740 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 Astex_2428 48762b76bdfd1548606beda61985de09 210 PRINTS PR01549 Autoinducer synthesis protein signature 39 61 2.2E-14 T 13-10-2018 IPR001690 Autoinducer synthase GO:0016740 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 Astex_0993 abfb07664bfccb16e19da698f34a8bd3 393 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 4 390 19.996 T 13-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 Astex_0993 abfb07664bfccb16e19da698f34a8bd3 393 Gene3D G3DSA:1.20.1530.10 1 392 1.2E-121 T 13-10-2018 IPR023171 Na/H antiporter domain superfamily Astex_0993 abfb07664bfccb16e19da698f34a8bd3 393 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 7 385 1.2E-102 T 13-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 Astex_0993 abfb07664bfccb16e19da698f34a8bd3 393 Pfam PF06965 Na+/H+ antiporter 1 6 386 3.0E-124 T 13-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 Astex_2758 2c256f99c102ff5f154f8ef635b52969 216 SUPERFAMILY SSF53474 9 212 1.22E-47 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_2758 2c256f99c102ff5f154f8ef635b52969 216 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 42 138 5.5E-8 T 13-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 Astex_2758 2c256f99c102ff5f154f8ef635b52969 216 Gene3D G3DSA:3.40.50.1820 2 216 1.1E-61 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1859 da6b1f146ab741f2bdfe1150f6574395 885 Gene3D G3DSA:1.10.1240.10 304 392 3.1E-40 T 13-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Astex_1859 da6b1f146ab741f2bdfe1150f6574395 885 TIGRFAM TIGR02082 metH: methionine synthase 8 851 0.0 T 13-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Astex_1859 da6b1f146ab741f2bdfe1150f6574395 885 Pfam PF02310 B12 binding domain 405 499 1.9E-19 T 13-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 Astex_1859 da6b1f146ab741f2bdfe1150f6574395 885 Gene3D G3DSA:3.10.196.10 565 882 2.8E-141 T 13-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Astex_1859 da6b1f146ab741f2bdfe1150f6574395 885 SMART SM01018 312 395 1.5E-45 T 13-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Astex_1859 da6b1f146ab741f2bdfe1150f6574395 885 Gene3D G3DSA:1.10.288.10 594 751 2.8E-141 T 13-10-2018 Astex_1859 da6b1f146ab741f2bdfe1150f6574395 885 Gene3D G3DSA:3.40.50.280 401 553 1.4E-54 T 13-10-2018 Astex_1859 da6b1f146ab741f2bdfe1150f6574395 885 SUPERFAMILY SSF51717 9 277 2.62E-89 T 13-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Astex_1859 da6b1f146ab741f2bdfe1150f6574395 885 Gene3D G3DSA:3.20.20.20 1 301 1.9E-126 T 13-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Astex_1859 da6b1f146ab741f2bdfe1150f6574395 885 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 595 867 3.0E-120 T 13-10-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Astex_1859 da6b1f146ab741f2bdfe1150f6574395 885 Pfam PF00809 Pterin binding enzyme 13 251 1.5E-59 T 13-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Astex_1859 da6b1f146ab741f2bdfe1150f6574395 885 SUPERFAMILY SSF52242 400 550 1.31E-44 T 13-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 Astex_1859 da6b1f146ab741f2bdfe1150f6574395 885 PIRSF PIRSF000381 1 854 0.0 T 13-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Astex_1859 da6b1f146ab741f2bdfe1150f6574395 885 Pfam PF02607 B12 binding domain 314 387 1.8E-26 T 13-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Astex_1859 da6b1f146ab741f2bdfe1150f6574395 885 SUPERFAMILY SSF56507 562 885 2.22E-124 T 13-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Astex_1859 da6b1f146ab741f2bdfe1150f6574395 885 SUPERFAMILY SSF47644 308 394 1.83E-28 T 13-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 Astex_2321 932a3542aa57bbe27db80645865075ad 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 392 402 5.6E-9 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_2321 932a3542aa57bbe27db80645865075ad 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 374 388 5.6E-9 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_2321 932a3542aa57bbe27db80645865075ad 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 409 427 5.6E-9 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_2321 932a3542aa57bbe27db80645865075ad 487 Gene3D G3DSA:1.10.287.130 191 264 1.3E-23 T 13-10-2018 Astex_2321 932a3542aa57bbe27db80645865075ad 487 SMART SM00388 197 264 2.8E-19 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_2321 932a3542aa57bbe27db80645865075ad 487 SUPERFAMILY SSF55874 253 435 4.02E-31 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_2321 932a3542aa57bbe27db80645865075ad 487 SUPERFAMILY SSF47384 180 264 5.49E-19 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Astex_2321 932a3542aa57bbe27db80645865075ad 487 Pfam PF00512 His Kinase A (phospho-acceptor) domain 198 262 8.2E-17 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_2321 932a3542aa57bbe27db80645865075ad 487 SMART SM00387 311 473 5.9E-30 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_2321 932a3542aa57bbe27db80645865075ad 487 Gene3D G3DSA:3.30.565.10 271 470 2.4E-30 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_2321 932a3542aa57bbe27db80645865075ad 487 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 312 433 1.4E-15 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_2484 3bc1fb112ffa99e23907f11f34352059 806 Gene3D G3DSA:3.40.50.300 569 765 5.3E-23 T 13-10-2018 Astex_2484 3bc1fb112ffa99e23907f11f34352059 806 SUPERFAMILY SSF52540 405 748 2.58E-47 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2484 3bc1fb112ffa99e23907f11f34352059 806 Gene3D G3DSA:3.40.50.300 435 568 2.3E-6 T 13-10-2018 Astex_2484 3bc1fb112ffa99e23907f11f34352059 806 SMART SM00382 446 706 5.0E-4 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_2484 3bc1fb112ffa99e23907f11f34352059 806 Pfam PF03135 CagE, TrbE, VirB family, component of type IV transporter system 187 394 6.7E-15 T 13-10-2018 IPR018145 CagE, TrbE, VirB component of type IV transporter system, central domain GO:0005524 Astex_1462 4b3035f6013f3b142805f1efff434133 1108 Pfam PF00512 His Kinase A (phospho-acceptor) domain 765 828 5.8E-11 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_1462 4b3035f6013f3b142805f1efff434133 1108 SMART SM00388 764 828 1.4E-13 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_1462 4b3035f6013f3b142805f1efff434133 1108 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 873 978 6.9E-19 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_1462 4b3035f6013f3b142805f1efff434133 1108 SUPERFAMILY SSF47384 750 829 9.02E-12 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Astex_1462 4b3035f6013f3b142805f1efff434133 1108 SMART SM00448 997 1106 5.1E-18 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1462 4b3035f6013f3b142805f1efff434133 1108 SUPERFAMILY SSF55874 818 978 1.09E-36 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_1462 4b3035f6013f3b142805f1efff434133 1108 Gene3D G3DSA:3.40.50.2300 995 1107 9.4E-21 T 13-10-2018 Astex_1462 4b3035f6013f3b142805f1efff434133 1108 SMART SM00387 872 980 7.8E-25 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_1462 4b3035f6013f3b142805f1efff434133 1108 Pfam PF00072 Response regulator receiver domain 999 1104 6.9E-17 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1462 4b3035f6013f3b142805f1efff434133 1108 Gene3D G3DSA:3.30.565.10 826 978 3.7E-33 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_1462 4b3035f6013f3b142805f1efff434133 1108 Pfam PF12860 PAS fold 617 727 5.1E-42 T 13-10-2018 Astex_1462 4b3035f6013f3b142805f1efff434133 1108 SUPERFAMILY SSF55785 604 724 2.3E-9 T 13-10-2018 IPR035965 PAS domain superfamily Astex_1462 4b3035f6013f3b142805f1efff434133 1108 PRINTS PR00344 Bacterial sensor protein C-terminal signature 940 958 3.4E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1462 4b3035f6013f3b142805f1efff434133 1108 PRINTS PR00344 Bacterial sensor protein C-terminal signature 908 922 3.4E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1462 4b3035f6013f3b142805f1efff434133 1108 PRINTS PR00344 Bacterial sensor protein C-terminal signature 964 977 3.4E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1462 4b3035f6013f3b142805f1efff434133 1108 SUPERFAMILY SSF52172 997 1106 7.4E-21 T 13-10-2018 IPR011006 CheY-like superfamily Astex_1462 4b3035f6013f3b142805f1efff434133 1108 Gene3D G3DSA:1.10.287.130 730 825 3.4E-13 T 13-10-2018 Astex_1462 4b3035f6013f3b142805f1efff434133 1108 Gene3D G3DSA:1.20.1730.10 38 467 7.2E-15 T 13-10-2018 IPR038377 Sodium/glucose symporter superfamily Astex_1462 4b3035f6013f3b142805f1efff434133 1108 Gene3D G3DSA:3.30.450.20 599 729 1.6E-10 T 13-10-2018 Astex_0868 1b76c85c735623babfc7df86cb96b31d 163 Pfam PF00072 Response regulator receiver domain 16 91 3.8E-11 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_0868 1b76c85c735623babfc7df86cb96b31d 163 SUPERFAMILY SSF52172 16 110 2.56E-17 T 13-10-2018 IPR011006 CheY-like superfamily Astex_0868 1b76c85c735623babfc7df86cb96b31d 163 Gene3D G3DSA:3.40.50.12740 15 162 1.9E-18 T 13-10-2018 Astex_1853 0ce7d3c720200f06bb9169ba39043212 225 Gene3D G3DSA:1.10.287.110 156 224 9.4E-6 T 13-10-2018 IPR036869 Chaperone J-domain superfamily Astex_1853 0ce7d3c720200f06bb9169ba39043212 225 SUPERFAMILY SSF46565 150 219 8.72E-9 T 13-10-2018 IPR036869 Chaperone J-domain superfamily Astex_1853 0ce7d3c720200f06bb9169ba39043212 225 Pfam PF05099 Tellurite resistance protein TerB 26 150 8.8E-30 T 13-10-2018 IPR007791 Co-chaperone DjlA, N-terminal Astex_1853 0ce7d3c720200f06bb9169ba39043212 225 Gene3D G3DSA:1.10.3680.10 23 146 3.0E-16 T 13-10-2018 IPR029024 TerB-like Astex_1853 0ce7d3c720200f06bb9169ba39043212 225 SUPERFAMILY SSF158682 28 173 4.97E-23 T 13-10-2018 IPR029024 TerB-like Astex_1450 4f82220115af1f1394812f5e1218fd7f 435 Pfam PF01435 Peptidase family M48 68 271 2.7E-28 T 13-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 Astex_1450 4f82220115af1f1394812f5e1218fd7f 435 Gene3D G3DSA:1.25.40.10 261 412 2.2E-7 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_1450 4f82220115af1f1394812f5e1218fd7f 435 SUPERFAMILY SSF48452 340 410 6.92E-7 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_1450 4f82220115af1f1394812f5e1218fd7f 435 Pfam PF13428 Tetratricopeptide repeat 373 411 4.3E-6 T 13-10-2018 Astex_3575 2290c43626919bdfbd7d0fd342ce1b4f 608 SUPERFAMILY SSF52467 181 374 1.87E-39 T 13-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily Astex_3575 2290c43626919bdfbd7d0fd342ce1b4f 608 Gene3D G3DSA:3.40.50.1220 212 389 1.4E-38 T 13-10-2018 Astex_3575 2290c43626919bdfbd7d0fd342ce1b4f 608 Gene3D G3DSA:3.40.50.970 390 570 1.3E-43 T 13-10-2018 Astex_3575 2290c43626919bdfbd7d0fd342ce1b4f 608 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 409 560 6.0E-34 T 13-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 Astex_3575 2290c43626919bdfbd7d0fd342ce1b4f 608 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 221 350 1.3E-32 T 13-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 Astex_3575 2290c43626919bdfbd7d0fd342ce1b4f 608 SUPERFAMILY SSF52518 389 596 1.05E-48 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold Astex_3575 2290c43626919bdfbd7d0fd342ce1b4f 608 Gene3D G3DSA:3.40.50.970 6 207 4.0E-32 T 13-10-2018 Astex_3575 2290c43626919bdfbd7d0fd342ce1b4f 608 TIGRFAM TIGR04377 myo_inos_iolD: 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase 5 603 1.4E-278 T 13-10-2018 IPR030817 3,5/4-Trihydroxycyclohexa-1,2-dione hydrolase GO:0016823|GO:0019310|GO:0030976 KEGG: 00562+3.7.1.22 Astex_3575 2290c43626919bdfbd7d0fd342ce1b4f 608 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 445 464 - T 13-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 Astex_3575 2290c43626919bdfbd7d0fd342ce1b4f 608 SUPERFAMILY SSF52518 6 209 9.68E-31 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold Astex_3575 2290c43626919bdfbd7d0fd342ce1b4f 608 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 7 197 9.2E-38 T 13-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 Astex_3601 85b5ae77395ab195784ad2dbe99f5cdf 952 Pfam PF00593 TonB dependent receptor 460 947 1.8E-29 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_3601 85b5ae77395ab195784ad2dbe99f5cdf 952 Pfam PF07715 TonB-dependent Receptor Plug Domain 67 169 2.8E-13 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_3601 85b5ae77395ab195784ad2dbe99f5cdf 952 Gene3D G3DSA:2.170.130.10 34 175 1.8E-18 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_3601 85b5ae77395ab195784ad2dbe99f5cdf 952 SUPERFAMILY SSF56935 46 952 6.2E-76 T 13-10-2018 Astex_3601 85b5ae77395ab195784ad2dbe99f5cdf 952 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 45 952 2.0E-178 T 13-10-2018 IPR010104 Bacterial TonB-dependent receptor Astex_0131 c77b3165bf185d5082d1b7487a4d18a0 191 Gene3D G3DSA:3.20.20.70 3 190 3.5E-31 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_0131 c77b3165bf185d5082d1b7487a4d18a0 191 SUPERFAMILY SSF51391 10 188 1.31E-26 T 13-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Astex_0131 c77b3165bf185d5082d1b7487a4d18a0 191 Pfam PF02581 Thiamine monophosphate synthase 22 187 5.6E-24 T 13-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Astex_1333 6bfe91ecb18a96ddf86144c7724a23d0 808 TIGRFAM TIGR00929 VirB4_CagE: type IV secretion/conjugal transfer ATPase, VirB4 family 14 791 1.2E-219 T 13-10-2018 IPR004346 CagE, TrbE, VirB component of type IV transporter system GO:0005524 Astex_1333 6bfe91ecb18a96ddf86144c7724a23d0 808 SUPERFAMILY SSF52540 400 747 5.76E-39 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1333 6bfe91ecb18a96ddf86144c7724a23d0 808 Pfam PF03135 CagE, TrbE, VirB family, component of type IV transporter system 184 390 1.9E-39 T 13-10-2018 IPR018145 CagE, TrbE, VirB component of type IV transporter system, central domain GO:0005524 Astex_3775 9a54793d548ffc0a5a487d3eeb82e3d0 228 PIRSF PIRSF009320 1 228 2.5E-32 T 13-10-2018 Astex_3775 9a54793d548ffc0a5a487d3eeb82e3d0 228 Pfam PF07015 VirC1 protein 1 189 1.5E-17 T 13-10-2018 IPR009744 VirC1 Astex_3775 9a54793d548ffc0a5a487d3eeb82e3d0 228 SUPERFAMILY SSF52540 1 218 1.97E-21 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_3775 9a54793d548ffc0a5a487d3eeb82e3d0 228 Gene3D G3DSA:3.40.50.300 3 227 9.2E-36 T 13-10-2018 Astex_2311 e86726a9a20ac371b80a50f43785fe3c 291 SUPERFAMILY SSF53448 3 271 2.7E-59 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_2311 e86726a9a20ac371b80a50f43785fe3c 291 Pfam PF00483 Nucleotidyl transferase 8 261 6.8E-23 T 13-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Astex_2311 e86726a9a20ac371b80a50f43785fe3c 291 Gene3D G3DSA:3.90.550.10 1 288 2.2E-79 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_3437 2e99b7b4a92f43c158a725a5dfec7b00 168 Pfam PF05751 FixH 23 163 1.5E-33 T 13-10-2018 IPR008620 Nitrogen fixation protein FixH Astex_0586 ec034afeb774097ae5905001158392bd 305 SUPERFAMILY SSF64518 1 305 1.96E-21 T 13-10-2018 Astex_0586 ec034afeb774097ae5905001158392bd 305 Pfam PF00700 Bacterial flagellin C-terminal helical region 225 304 1.9E-8 T 13-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 Astex_0673 63e1e2eecbe31944e375f5108f96156d 205 Pfam PF12276 Protein of unknown function (DUF3617) 13 174 5.3E-7 T 13-10-2018 IPR022061 Protein of unknown function DUF3617 Astex_1023 f9044219e44b67e9cde4afcee816cf51 483 SUPERFAMILY SSF103378 12 482 4.32E-165 T 13-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 Astex_1023 f9044219e44b67e9cde4afcee816cf51 483 TIGRFAM TIGR02330 prpD: 2-methylcitrate dehydratase 13 483 4.6E-258 T 13-10-2018 IPR012705 2-methylcitrate dehydratase PrpD GO:0019629|GO:0047547|GO:0051537 KEGG: 00640+4.2.1.79 Astex_1023 f9044219e44b67e9cde4afcee816cf51 483 Pfam PF03972 MmgE/PrpD family 18 466 4.7E-164 T 13-10-2018 IPR005656 MmgE/PrpD GO:0016829 Astex_1023 f9044219e44b67e9cde4afcee816cf51 483 Gene3D G3DSA:3.30.1330.120 285 426 6.6E-208 T 13-10-2018 Astex_1023 f9044219e44b67e9cde4afcee816cf51 483 Gene3D G3DSA:1.10.4100.10 22 461 6.6E-208 T 13-10-2018 Astex_3651 dbb0cd3c6a1aac521154be3ecac32f20 126 TIGRFAM TIGR01550 DOC_P1: death-on-curing family protein 5 118 7.2E-20 T 13-10-2018 IPR006440 Death on curing protein GO:0016301 Astex_3651 dbb0cd3c6a1aac521154be3ecac32f20 126 Gene3D G3DSA:1.20.120.1870 2 126 2.5E-37 T 13-10-2018 Astex_3651 dbb0cd3c6a1aac521154be3ecac32f20 126 Pfam PF02661 Fic/DOC family 4 81 1.9E-12 T 13-10-2018 IPR003812 Fido domain Astex_3651 dbb0cd3c6a1aac521154be3ecac32f20 126 PIRSF PIRSF018297 1 125 3.2E-36 T 13-10-2018 IPR006440 Death on curing protein GO:0016301 Astex_3651 dbb0cd3c6a1aac521154be3ecac32f20 126 SUPERFAMILY SSF140931 5 110 1.96E-10 T 13-10-2018 IPR036597 Fido-like domain superfamily Astex_0889 5b139e7f52a12e0b6705fd920121dffd 495 Pfam PF03055 Retinal pigment epithelial membrane protein 55 495 8.3E-75 T 13-10-2018 IPR004294 Carotenoid oxygenase GO:0016702|GO:0055114 Astex_2103 52136dd7a39016d091ddb42ebe59988b 547 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 331 392 2.4E-13 T 13-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Astex_2103 52136dd7a39016d091ddb42ebe59988b 547 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 52 110 5.1E-17 T 13-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Astex_2103 52136dd7a39016d091ddb42ebe59988b 547 SUPERFAMILY SSF55124 1 125 6.38E-29 T 13-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Astex_2103 52136dd7a39016d091ddb42ebe59988b 547 Gene3D G3DSA:3.30.413.10 402 547 1.2E-28 T 13-10-2018 Astex_2103 52136dd7a39016d091ddb42ebe59988b 547 SUPERFAMILY SSF56014 120 267 2.09E-43 T 13-10-2018 Astex_2103 52136dd7a39016d091ddb42ebe59988b 547 SUPERFAMILY SSF56014 404 545 9.55E-36 T 13-10-2018 Astex_2103 52136dd7a39016d091ddb42ebe59988b 547 SUPERFAMILY SSF55124 247 416 1.03E-22 T 13-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Astex_2103 52136dd7a39016d091ddb42ebe59988b 547 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 427 544 9.1E-9 T 13-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Astex_2103 52136dd7a39016d091ddb42ebe59988b 547 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 119 267 3.2E-36 T 13-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 Astex_1329 dc5d3557e3e4900d7e0985f99c88d794 328 Pfam PF00437 Type II/IV secretion system protein 17 308 1.3E-75 T 13-10-2018 IPR001482 Type II/IV secretion system protein Astex_1329 dc5d3557e3e4900d7e0985f99c88d794 328 SUPERFAMILY SSF52540 8 280 6.19E-42 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1329 dc5d3557e3e4900d7e0985f99c88d794 328 Gene3D G3DSA:3.30.450.90 11 119 5.6E-32 T 13-10-2018 Astex_1329 dc5d3557e3e4900d7e0985f99c88d794 328 TIGRFAM TIGR02788 VirB11: P-type DNA transfer ATPase VirB11 22 318 1.6E-94 T 13-10-2018 IPR014155 Type IV secretion system protein VirB11 GO:0043684|GO:0044097 Astex_1329 dc5d3557e3e4900d7e0985f99c88d794 328 Gene3D G3DSA:3.40.50.300 138 327 6.8E-55 T 13-10-2018 Astex_0236 aa32f0001bf78e5d8f626a8f427eb098 294 SUPERFAMILY SSF52210 123 291 5.23E-51 T 13-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Astex_0236 aa32f0001bf78e5d8f626a8f427eb098 294 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 292 42.55 T 13-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 Astex_0236 aa32f0001bf78e5d8f626a8f427eb098 294 Pfam PF00549 CoA-ligase 151 274 4.1E-19 T 13-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Astex_0236 aa32f0001bf78e5d8f626a8f427eb098 294 Gene3D G3DSA:3.40.50.720 2 123 3.2E-52 T 13-10-2018 Astex_0236 aa32f0001bf78e5d8f626a8f427eb098 294 PIRSF PIRSF001553 1 294 1.7E-127 T 13-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 Astex_0236 aa32f0001bf78e5d8f626a8f427eb098 294 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 152 181 - T 13-10-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site Astex_0236 aa32f0001bf78e5d8f626a8f427eb098 294 Gene3D G3DSA:3.40.50.261 124 292 1.4E-69 T 13-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 Astex_0236 aa32f0001bf78e5d8f626a8f427eb098 294 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 4 292 1.4E-136 T 13-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 Astex_0236 aa32f0001bf78e5d8f626a8f427eb098 294 SUPERFAMILY SSF51735 1 122 2.49E-44 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_0236 aa32f0001bf78e5d8f626a8f427eb098 294 SMART SM00881 4 100 9.5E-35 T 13-10-2018 IPR003781 CoA-binding GO:0048037 Astex_0236 aa32f0001bf78e5d8f626a8f427eb098 294 Pfam PF02629 CoA binding domain 7 99 1.1E-30 T 13-10-2018 IPR003781 CoA-binding GO:0048037 Astex_0236 aa32f0001bf78e5d8f626a8f427eb098 294 PRINTS PR01798 Succinyl-CoA synthase signature 208 221 1.1E-40 T 13-10-2018 Astex_0236 aa32f0001bf78e5d8f626a8f427eb098 294 PRINTS PR01798 Succinyl-CoA synthase signature 177 195 1.1E-40 T 13-10-2018 Astex_0236 aa32f0001bf78e5d8f626a8f427eb098 294 PRINTS PR01798 Succinyl-CoA synthase signature 82 99 1.1E-40 T 13-10-2018 Astex_0236 aa32f0001bf78e5d8f626a8f427eb098 294 PRINTS PR01798 Succinyl-CoA synthase signature 244 261 1.1E-40 T 13-10-2018 Astex_0236 aa32f0001bf78e5d8f626a8f427eb098 294 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 240 253 - T 13-10-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site Astex_0112 daceb701dadde6af49dfb017798377bd 216 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 129 157 - T 13-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 Astex_0112 daceb701dadde6af49dfb017798377bd 216 SUPERFAMILY SSF51161 68 211 1.8E-41 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily Astex_0112 daceb701dadde6af49dfb017798377bd 216 Gene3D G3DSA:2.160.10.10 21 215 5.2E-55 T 13-10-2018 Astex_0112 daceb701dadde6af49dfb017798377bd 216 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 120 154 1.5E-9 T 13-10-2018 IPR001451 Hexapeptide repeat Astex_1651 79b1344ace8c37d4a98abfadfc3d59e4 356 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 20 126 1.7E-33 T 13-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_1651 79b1344ace8c37d4a98abfadfc3d59e4 356 PIRSF PIRSF000149 17 355 1.0E-132 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_1651 79b1344ace8c37d4a98abfadfc3d59e4 356 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 172 179 - T 13-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_1651 79b1344ace8c37d4a98abfadfc3d59e4 356 Gene3D G3DSA:3.30.360.10 173 337 2.1E-145 T 13-10-2018 Astex_1651 79b1344ace8c37d4a98abfadfc3d59e4 356 SUPERFAMILY SSF51735 17 195 1.14E-57 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_1651 79b1344ace8c37d4a98abfadfc3d59e4 356 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 179 335 6.1E-64 T 13-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_1651 79b1344ace8c37d4a98abfadfc3d59e4 356 SUPERFAMILY SSF55347 174 336 6.86E-70 T 13-10-2018 Astex_1651 79b1344ace8c37d4a98abfadfc3d59e4 356 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 20 346 5.8E-129 T 13-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_1651 79b1344ace8c37d4a98abfadfc3d59e4 356 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 195 211 3.1E-42 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_1651 79b1344ace8c37d4a98abfadfc3d59e4 356 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 291 306 3.1E-42 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_1651 79b1344ace8c37d4a98abfadfc3d59e4 356 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 132 145 3.1E-42 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_1651 79b1344ace8c37d4a98abfadfc3d59e4 356 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 168 186 3.1E-42 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_1651 79b1344ace8c37d4a98abfadfc3d59e4 356 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 251 268 3.1E-42 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_1651 79b1344ace8c37d4a98abfadfc3d59e4 356 Gene3D G3DSA:3.40.50.720 20 347 2.1E-145 T 13-10-2018 Astex_1651 79b1344ace8c37d4a98abfadfc3d59e4 356 SMART SM00846 19 174 1.0E-91 T 13-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_1614 5a55ed5590066d4d4708e6661a16dfa1 133 Pfam PF07166 Protein of unknown function (DUF1398) 21 124 8.6E-6 T 13-10-2018 IPR009833 Uncharacterised protein DUF1398 Astex_1614 5a55ed5590066d4d4708e6661a16dfa1 133 SUPERFAMILY SSF160419 14 126 2.48E-10 T 13-10-2018 IPR036696 YdfO-like superfamily Astex_1276 7d6ad95225f2576a558950fd9c62ecc6 467 Pfam PF02321 Outer membrane efflux protein 66 250 1.5E-16 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Astex_1276 7d6ad95225f2576a558950fd9c62ecc6 467 Pfam PF02321 Outer membrane efflux protein 281 462 1.0E-26 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Astex_1276 7d6ad95225f2576a558950fd9c62ecc6 467 Gene3D G3DSA:2.20.200.10 103 353 7.0E-120 T 13-10-2018 Astex_1276 7d6ad95225f2576a558950fd9c62ecc6 467 Gene3D G3DSA:1.20.1600.10 57 465 7.0E-120 T 13-10-2018 Astex_1276 7d6ad95225f2576a558950fd9c62ecc6 467 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 12 463 1.8E-102 T 13-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 Astex_1276 7d6ad95225f2576a558950fd9c62ecc6 467 SUPERFAMILY SSF56954 2 465 5.49E-97 T 13-10-2018 Astex_2040 b2a814c943dfcb13cb2cc91da8a9a278 423 Gene3D G3DSA:3.40.50.12780 15 323 1.3E-35 T 13-10-2018 Astex_2040 b2a814c943dfcb13cb2cc91da8a9a278 423 TIGRFAM TIGR02304 aden_form_hyp: putative adenylate-forming enzyme 11 422 4.4E-83 T 13-10-2018 IPR012685 Conserved hypothetical protein CHP02304, F390 synthetase-related Astex_2040 b2a814c943dfcb13cb2cc91da8a9a278 423 SUPERFAMILY SSF56801 103 328 6.15E-7 T 13-10-2018 Astex_1112 fe921f2d04735e5e88969b6dfb460c61 810 Pfam PF00959 Phage lysozyme 33 128 3.0E-14 T 13-10-2018 IPR002196 Glycoside hydrolase, family 24 GO:0003796|GO:0009253|GO:0016998 Astex_1112 fe921f2d04735e5e88969b6dfb460c61 810 SUPERFAMILY SSF53955 4 150 7.67E-36 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily Astex_1112 fe921f2d04735e5e88969b6dfb460c61 810 Gene3D G3DSA:1.10.530.40 6 154 1.3E-43 T 13-10-2018 Astex_2731 84536d91cf5daad0e1bd046682ce2b65 655 SUPERFAMILY SSF55545 40 183 3.93E-20 T 13-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 Astex_2731 84536d91cf5daad0e1bd046682ce2b65 655 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 42 182 3.1E-22 T 13-10-2018 IPR015882 Beta-hexosaminidase, bacterial type, N-terminal Astex_2731 84536d91cf5daad0e1bd046682ce2b65 655 Gene3D G3DSA:3.20.20.80 184 504 9.7E-98 T 13-10-2018 Astex_2731 84536d91cf5daad0e1bd046682ce2b65 655 SUPERFAMILY SSF140657 538 648 3.14E-5 T 13-10-2018 Astex_2731 84536d91cf5daad0e1bd046682ce2b65 655 Pfam PF07555 beta-N-acetylglucosaminidase 188 497 3.9E-101 T 13-10-2018 IPR011496 Beta-N-acetylglucosaminidase MetaCyc: PWY-7437 Astex_2731 84536d91cf5daad0e1bd046682ce2b65 655 SUPERFAMILY SSF51445 185 511 3.16E-93 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_2731 84536d91cf5daad0e1bd046682ce2b65 655 Gene3D G3DSA:3.30.379.10 30 182 5.9E-25 T 13-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 Astex_2731 84536d91cf5daad0e1bd046682ce2b65 655 Gene3D G3DSA:1.20.58.460 512 648 9.8E-9 T 13-10-2018 Astex_1848 797d5b1674d052bb0c360ca8a9f9ee5f 96 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 70 5.5E-10 T 13-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain Astex_1848 797d5b1674d052bb0c360ca8a9f9ee5f 96 Gene3D G3DSA:3.30.70.100 1 96 9.0E-18 T 13-10-2018 Astex_1848 797d5b1674d052bb0c360ca8a9f9ee5f 96 SUPERFAMILY SSF54909 1 90 1.53E-13 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel Astex_3761 6125faeac7708bd2d712fa383e8f51f9 140 Pfam PF03230 Antirestriction protein 50 140 2.2E-33 T 13-10-2018 IPR004914 Antirestriction protein Astex_3761 6125faeac7708bd2d712fa383e8f51f9 140 Gene3D G3DSA:1.10.472.120 4 140 1.0E-41 T 13-10-2018 Astex_3761 6125faeac7708bd2d712fa383e8f51f9 140 ProDom PD012854 PLASMID KLCA ANTIRESTRICTION YFJX YCIB ARDB STABLE YFEB Z1216 C0275 50 140 3.0E-17 T 13-10-2018 IPR004914 Antirestriction protein Astex_1417 555898b9be21480e4f0ef0aa00dcdae0 268 TIGRFAM TIGR01400 fliR: flagellar biosynthetic protein FliR 24 264 3.8E-51 T 13-10-2018 IPR006303 Flagellar biosynthesis protein FliR GO:0016021|GO:0044780 Astex_1417 555898b9be21480e4f0ef0aa00dcdae0 268 Pfam PF01311 Bacterial export proteins, family 1 25 258 1.6E-50 T 13-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 Astex_1417 555898b9be21480e4f0ef0aa00dcdae0 268 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 193 215 6.2E-17 T 13-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 Astex_1417 555898b9be21480e4f0ef0aa00dcdae0 268 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 93 112 6.2E-17 T 13-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 Astex_1417 555898b9be21480e4f0ef0aa00dcdae0 268 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 33 54 6.2E-17 T 13-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 Astex_1417 555898b9be21480e4f0ef0aa00dcdae0 268 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 215 234 6.2E-17 T 13-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 Astex_0745 9eccc8c3fc4161ce426eb5eabb66966b 314 SUPERFAMILY SSF54782 224 311 3.27E-14 T 13-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Astex_0745 9eccc8c3fc4161ce426eb5eabb66966b 314 SUPERFAMILY SSF53850 5 216 3.11E-71 T 13-10-2018 Astex_0745 9eccc8c3fc4161ce426eb5eabb66966b 314 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 235 251 - T 13-10-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Astex_0745 9eccc8c3fc4161ce426eb5eabb66966b 314 Gene3D G3DSA:3.30.160.40 225 312 8.5E-15 T 13-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Astex_0745 9eccc8c3fc4161ce426eb5eabb66966b 314 PIRSF PIRSF001438 1 313 1.1E-102 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Astex_0745 9eccc8c3fc4161ce426eb5eabb66966b 314 PRINTS PR00151 Porphobilinogen deaminase signature 81 100 1.9E-34 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Astex_0745 9eccc8c3fc4161ce426eb5eabb66966b 314 PRINTS PR00151 Porphobilinogen deaminase signature 50 70 1.9E-34 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Astex_0745 9eccc8c3fc4161ce426eb5eabb66966b 314 PRINTS PR00151 Porphobilinogen deaminase signature 234 251 1.9E-34 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Astex_0745 9eccc8c3fc4161ce426eb5eabb66966b 314 PRINTS PR00151 Porphobilinogen deaminase signature 148 165 1.9E-34 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Astex_0745 9eccc8c3fc4161ce426eb5eabb66966b 314 PRINTS PR00151 Porphobilinogen deaminase signature 129 146 1.9E-34 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Astex_0745 9eccc8c3fc4161ce426eb5eabb66966b 314 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 231 301 3.2E-7 T 13-10-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Astex_0745 9eccc8c3fc4161ce426eb5eabb66966b 314 Gene3D G3DSA:3.40.190.10 108 207 7.6E-76 T 13-10-2018 Astex_0745 9eccc8c3fc4161ce426eb5eabb66966b 314 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 5 215 6.4E-72 T 13-10-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Astex_0745 9eccc8c3fc4161ce426eb5eabb66966b 314 Gene3D G3DSA:3.40.190.10 5 214 7.6E-76 T 13-10-2018 Astex_0745 9eccc8c3fc4161ce426eb5eabb66966b 314 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 5 294 6.1E-97 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Astex_0745 9eccc8c3fc4161ce426eb5eabb66966b 314 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 4 304 33.756 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 Astex_2929 7c49e89adbc2e6c21dd1acf169f7f9d4 326 SUPERFAMILY SSF53901 7 325 1.04E-70 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 Astex_2929 7c49e89adbc2e6c21dd1acf169f7f9d4 326 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 4 326 69.99 T 13-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 Astex_2929 7c49e89adbc2e6c21dd1acf169f7f9d4 326 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 109 192 9.0E-31 T 13-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 Astex_2929 7c49e89adbc2e6c21dd1acf169f7f9d4 326 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 237 325 1.8E-32 T 13-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 Astex_2929 7c49e89adbc2e6c21dd1acf169f7f9d4 326 Gene3D G3DSA:3.40.47.10 2 326 1.0E-123 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 Astex_2929 7c49e89adbc2e6c21dd1acf169f7f9d4 326 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 6 325 1.2E-122 T 13-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 Astex_2523 f63cbeb47ecca43b250be0ee17d72682 524 SUPERFAMILY SSF56235 4 524 7.14E-139 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Astex_2523 f63cbeb47ecca43b250be0ee17d72682 524 Gene3D G3DSA:1.10.246.130 234 339 3.4E-13 T 13-10-2018 Astex_2523 f63cbeb47ecca43b250be0ee17d72682 524 Gene3D G3DSA:3.60.20.40 340 524 6.5E-62 T 13-10-2018 Astex_2523 f63cbeb47ecca43b250be0ee17d72682 524 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 247 266 2.3E-21 T 13-10-2018 Astex_2523 f63cbeb47ecca43b250be0ee17d72682 524 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 339 357 2.3E-21 T 13-10-2018 Astex_2523 f63cbeb47ecca43b250be0ee17d72682 524 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 363 381 2.3E-21 T 13-10-2018 Astex_2523 f63cbeb47ecca43b250be0ee17d72682 524 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 394 409 2.3E-21 T 13-10-2018 Astex_2523 f63cbeb47ecca43b250be0ee17d72682 524 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 120 139 2.3E-21 T 13-10-2018 Astex_2523 f63cbeb47ecca43b250be0ee17d72682 524 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 32 57 2.3E-21 T 13-10-2018 Astex_2523 f63cbeb47ecca43b250be0ee17d72682 524 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 101 119 2.3E-21 T 13-10-2018 Astex_2523 f63cbeb47ecca43b250be0ee17d72682 524 Pfam PF01019 Gamma-glutamyltranspeptidase 25 519 1.4E-117 T 13-10-2018 Astex_2903 35996ae94ac6fe8ab29536acd3d5c064 265 TIGRFAM TIGR00444 mazG: MazG family protein 15 260 2.2E-93 T 13-10-2018 IPR011551 NTP pyrophosphohydrolase MazG Astex_2903 35996ae94ac6fe8ab29536acd3d5c064 265 SUPERFAMILY SSF101386 140 236 1.44E-23 T 13-10-2018 Astex_2903 35996ae94ac6fe8ab29536acd3d5c064 265 Gene3D G3DSA:1.10.287.1080 134 264 2.8E-44 T 13-10-2018 Astex_2903 35996ae94ac6fe8ab29536acd3d5c064 265 Gene3D G3DSA:1.10.287.1080 7 130 1.7E-44 T 13-10-2018 Astex_2903 35996ae94ac6fe8ab29536acd3d5c064 265 SUPERFAMILY SSF101386 7 109 1.38E-25 T 13-10-2018 Astex_2903 35996ae94ac6fe8ab29536acd3d5c064 265 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 32 105 6.4E-29 T 13-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core Astex_2903 35996ae94ac6fe8ab29536acd3d5c064 265 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 170 229 1.6E-6 T 13-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core Astex_3717 13a4f75783d223edad58ea09f591e8ae 136 Gene3D G3DSA:1.25.10.10 23 135 1.0E-15 T 13-10-2018 IPR011989 Armadillo-like helical Astex_3717 13a4f75783d223edad58ea09f591e8ae 136 SUPERFAMILY SSF48371 38 127 1.5E-9 T 13-10-2018 IPR016024 Armadillo-type fold Astex_1375 07bda6bb702f012a159da8c61fa30b8e 459 SUPERFAMILY SSF51445 30 373 1.67E-79 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_1375 07bda6bb702f012a159da8c61fa30b8e 459 Gene3D G3DSA:3.20.20.80 26 374 4.1E-112 T 13-10-2018 Astex_1375 07bda6bb702f012a159da8c61fa30b8e 459 Pfam PF07745 Glycosyl hydrolase family 53 33 369 2.4E-106 T 13-10-2018 IPR011683 Glycosyl hydrolase family 53 GO:0015926 Astex_2596 68236264dadf566a9ce86e6a870fbb00 403 Gene3D G3DSA:1.20.1250.20 196 394 1.6E-42 T 13-10-2018 Astex_2596 68236264dadf566a9ce86e6a870fbb00 403 Pfam PF07690 Major Facilitator Superfamily 19 350 5.4E-40 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Astex_2596 68236264dadf566a9ce86e6a870fbb00 403 Gene3D G3DSA:1.20.1250.20 6 190 3.1E-34 T 13-10-2018 Astex_2596 68236264dadf566a9ce86e6a870fbb00 403 SUPERFAMILY SSF103473 8 391 7.19E-53 T 13-10-2018 IPR036259 MFS transporter superfamily Astex_1210 f5a029eaab5bfd2ffd2b1f214ee63dc7 377 TIGRFAM TIGR02226 two_anch: N-terminal double-transmembrane domain 3 80 4.3E-20 T 13-10-2018 IPR011933 Double transmembrane domain Astex_1210 f5a029eaab5bfd2ffd2b1f214ee63dc7 377 Pfam PF07584 Aerotolerance regulator N-terminal 1 76 2.6E-10 T 13-10-2018 IPR024163 Aerotolerance regulator, N-terminal Astex_3414 f43ab62e1abc5c517143cb3694826335 816 Pfam PF12704 MacB-like periplasmic core domain 22 241 3.1E-16 T 13-10-2018 IPR025857 MacB-like periplasmic core domain Astex_3414 f43ab62e1abc5c517143cb3694826335 816 Pfam PF12704 MacB-like periplasmic core domain 431 618 2.3E-8 T 13-10-2018 IPR025857 MacB-like periplasmic core domain Astex_3414 f43ab62e1abc5c517143cb3694826335 816 Pfam PF02687 FtsX-like permease family 722 805 4.5E-8 T 13-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 Astex_3414 f43ab62e1abc5c517143cb3694826335 816 Pfam PF02687 FtsX-like permease family 313 400 2.5E-8 T 13-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 Astex_3754 54136d9f7e80351b8827bec301e46aa8 135 PIRSF PIRSF002070 3 133 2.7E-27 T 13-10-2018 Astex_3754 54136d9f7e80351b8827bec301e46aa8 135 Hamap MF_00984 Single-stranded DNA-binding protein. 8 114 23.348 T 13-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 Astex_3754 54136d9f7e80351b8827bec301e46aa8 135 Gene3D G3DSA:2.40.50.140 7 132 1.4E-29 T 13-10-2018 Astex_3754 54136d9f7e80351b8827bec301e46aa8 135 Pfam PF00436 Single-strand binding protein family 8 107 1.7E-25 T 13-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 Astex_3754 54136d9f7e80351b8827bec301e46aa8 135 SUPERFAMILY SSF50249 8 135 3.39E-33 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Astex_3754 54136d9f7e80351b8827bec301e46aa8 135 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 7 128 5.5E-32 T 13-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 Astex_1800 85d13fad9d8bbd8bcdcaa6f68feae782 91 Pfam PF02583 Metal-sensitive transcriptional repressor 9 88 5.8E-22 T 13-10-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 Astex_1800 85d13fad9d8bbd8bcdcaa6f68feae782 91 Gene3D G3DSA:1.20.58.1000 1 91 8.4E-29 T 13-10-2018 IPR038390 Metal-sensitive transcriptional repressor superfamily Astex_1320 45b0df2d35439e55074e9300b120881d 306 PRINTS PR00990 Ribokinase signature 7 28 1.5E-28 T 13-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 Astex_1320 45b0df2d35439e55074e9300b120881d 306 PRINTS PR00990 Ribokinase signature 174 189 1.5E-28 T 13-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 Astex_1320 45b0df2d35439e55074e9300b120881d 306 PRINTS PR00990 Ribokinase signature 34 53 1.5E-28 T 13-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 Astex_1320 45b0df2d35439e55074e9300b120881d 306 PRINTS PR00990 Ribokinase signature 218 229 1.5E-28 T 13-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 Astex_1320 45b0df2d35439e55074e9300b120881d 306 PRINTS PR00990 Ribokinase signature 106 119 1.5E-28 T 13-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 Astex_1320 45b0df2d35439e55074e9300b120881d 306 Pfam PF00294 pfkB family carbohydrate kinase 3 291 2.4E-63 T 13-10-2018 IPR011611 Carbohydrate kinase PfkB Astex_1320 45b0df2d35439e55074e9300b120881d 306 Gene3D G3DSA:3.40.1190.20 1 305 6.4E-89 T 13-10-2018 IPR029056 Ribokinase-like Astex_1320 45b0df2d35439e55074e9300b120881d 306 SUPERFAMILY SSF53613 4 304 1.37E-76 T 13-10-2018 IPR029056 Ribokinase-like Astex_1320 45b0df2d35439e55074e9300b120881d 306 Hamap MF_01987 Ribokinase [rbsK]. 3 301 22.751 T 13-10-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 Astex_0621 6fac505a59e415ac32c0e4e09dfaed3f 125 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 24 90 4.5E-15 T 13-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 Astex_0621 6fac505a59e415ac32c0e4e09dfaed3f 125 SUPERFAMILY SSF48295 22 111 2.35E-19 T 13-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 Astex_0621 6fac505a59e415ac32c0e4e09dfaed3f 125 Gene3D G3DSA:1.10.1750.10 9 113 4.2E-19 T 13-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 Astex_0621 6fac505a59e415ac32c0e4e09dfaed3f 125 SMART SM00760 21 90 2.8E-10 T 13-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 Astex_0390 c404695ef239f4378ec52ed6db3b9265 536 ProSitePatterns PS00941 Carboxylesterases type-B signature 2. 102 112 - T 13-10-2018 IPR019819 Carboxylesterase type B, conserved site Astex_0390 c404695ef239f4378ec52ed6db3b9265 536 SUPERFAMILY SSF53474 31 529 7.25E-103 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_0390 c404695ef239f4378ec52ed6db3b9265 536 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 208 223 - T 13-10-2018 IPR019826 Carboxylesterase type B, active site Astex_0390 c404695ef239f4378ec52ed6db3b9265 536 Pfam PF00135 Carboxylesterase family 32 522 5.1E-88 T 13-10-2018 IPR002018 Carboxylesterase, type B Astex_0390 c404695ef239f4378ec52ed6db3b9265 536 Gene3D G3DSA:3.40.50.1820 24 530 6.1E-126 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_3502 c073f5b486c7c70d1a164f0bba479b89 425 SUPERFAMILY SSF141868 155 401 7.45E-39 T 13-10-2018 IPR035919 EAL domain superfamily Astex_3502 c073f5b486c7c70d1a164f0bba479b89 425 Pfam PF00563 EAL domain 154 396 2.3E-51 T 13-10-2018 IPR001633 EAL domain Astex_3502 c073f5b486c7c70d1a164f0bba479b89 425 Gene3D G3DSA:3.20.20.450 151 403 2.5E-44 T 13-10-2018 IPR035919 EAL domain superfamily Astex_3502 c073f5b486c7c70d1a164f0bba479b89 425 SMART SM00052 148 401 8.0E-11 T 13-10-2018 IPR001633 EAL domain Astex_1618 a1629270302ba18649a9f1a9845b366e 270 SUPERFAMILY SSF53474 35 257 4.65E-42 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1618 a1629270302ba18649a9f1a9845b366e 270 Gene3D G3DSA:3.40.50.1820 28 264 9.2E-57 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1618 a1629270302ba18649a9f1a9845b366e 270 Pfam PF00561 alpha/beta hydrolase fold 64 152 8.8E-11 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Astex_1055 b0d9ac94eb01bb7ae67da671c52f2055 234 Gene3D G3DSA:1.20.1080.10 127 232 3.1E-7 T 13-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 Astex_1055 b0d9ac94eb01bb7ae67da671c52f2055 234 Gene3D G3DSA:1.20.1080.10 4 126 4.3E-22 T 13-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 Astex_1055 b0d9ac94eb01bb7ae67da671c52f2055 234 SUPERFAMILY SSF81338 8 220 4.19E-40 T 13-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 Astex_1055 b0d9ac94eb01bb7ae67da671c52f2055 234 PRINTS PR00783 Major intrinsic protein family signature 132 150 1.3E-20 T 13-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 Astex_1055 b0d9ac94eb01bb7ae67da671c52f2055 234 PRINTS PR00783 Major intrinsic protein family signature 10 29 1.3E-20 T 13-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 Astex_1055 b0d9ac94eb01bb7ae67da671c52f2055 234 PRINTS PR00783 Major intrinsic protein family signature 89 108 1.3E-20 T 13-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 Astex_1055 b0d9ac94eb01bb7ae67da671c52f2055 234 PRINTS PR00783 Major intrinsic protein family signature 52 76 1.3E-20 T 13-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 Astex_1055 b0d9ac94eb01bb7ae67da671c52f2055 234 PRINTS PR00783 Major intrinsic protein family signature 199 219 1.3E-20 T 13-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 Astex_1055 b0d9ac94eb01bb7ae67da671c52f2055 234 Pfam PF00230 Major intrinsic protein 157 216 3.4E-5 T 13-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 Astex_1055 b0d9ac94eb01bb7ae67da671c52f2055 234 Pfam PF00230 Major intrinsic protein 7 147 2.9E-18 T 13-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 Astex_1150 a648be4f49342852e7c8af74f7ebcae3 195 SUPERFAMILY SSF50715 4 192 4.53E-52 T 13-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Astex_1150 a648be4f49342852e7c8af74f7ebcae3 195 Gene3D G3DSA:2.40.240.10 2 96 2.4E-24 T 13-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 Astex_1150 a648be4f49342852e7c8af74f7ebcae3 195 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 6 182 9.7E-43 T 13-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 Astex_1150 a648be4f49342852e7c8af74f7ebcae3 195 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 102 185 2.9E-26 T 13-10-2018 IPR020057 Ribosomal protein L25, beta domain Astex_1150 a648be4f49342852e7c8af74f7ebcae3 195 Pfam PF01386 Ribosomal L25p family 7 93 4.6E-23 T 13-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 Astex_1150 a648be4f49342852e7c8af74f7ebcae3 195 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 6 96 1.0E-35 T 13-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 Astex_1150 a648be4f49342852e7c8af74f7ebcae3 195 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 4 186 27.208 T 13-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 Astex_1150 a648be4f49342852e7c8af74f7ebcae3 195 Gene3D G3DSA:2.170.120.20 99 193 1.9E-22 T 13-10-2018 IPR037121 Ribosomal protein L25, C-terminal Astex_3100 13fbbc96ac874ee7da0ff7d365ecdbda 163 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 5 58 1.4E-16 T 13-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 Astex_3100 13fbbc96ac874ee7da0ff7d365ecdbda 163 SUPERFAMILY SSF52374 3 158 2.01E-41 T 13-10-2018 Astex_3100 13fbbc96ac874ee7da0ff7d365ecdbda 163 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 4 161 33.405 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 Astex_3100 13fbbc96ac874ee7da0ff7d365ecdbda 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 22 43 1.1E-31 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 Astex_3100 13fbbc96ac874ee7da0ff7d365ecdbda 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 4 22 1.1E-31 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 Astex_3100 13fbbc96ac874ee7da0ff7d365ecdbda 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 88 104 1.1E-31 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 Astex_3100 13fbbc96ac874ee7da0ff7d365ecdbda 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 115 137 1.1E-31 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 Astex_3100 13fbbc96ac874ee7da0ff7d365ecdbda 163 Gene3D G3DSA:3.40.50.620 1 163 1.3E-53 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Astex_3100 13fbbc96ac874ee7da0ff7d365ecdbda 163 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 6 159 1.6E-57 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 Astex_3100 13fbbc96ac874ee7da0ff7d365ecdbda 163 Pfam PF01467 Cytidylyltransferase-like 7 135 2.2E-17 T 13-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 Astex_1972 a4e6b2569e038c70882d23dfd9bd89a2 621 Pfam PF00664 ABC transporter transmembrane region 40 316 4.4E-30 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 Astex_1972 a4e6b2569e038c70882d23dfd9bd89a2 621 ProSitePatterns PS00211 ABC transporters family signature. 502 516 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Astex_1972 a4e6b2569e038c70882d23dfd9bd89a2 621 SUPERFAMILY SSF90123 21 353 2.75E-58 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Astex_1972 a4e6b2569e038c70882d23dfd9bd89a2 621 Gene3D G3DSA:3.40.50.300 355 615 2.8E-97 T 13-10-2018 Astex_1972 a4e6b2569e038c70882d23dfd9bd89a2 621 SMART SM00382 390 576 9.7E-18 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_1972 a4e6b2569e038c70882d23dfd9bd89a2 621 Gene3D G3DSA:1.20.1560.10 24 353 4.1E-107 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Astex_1972 a4e6b2569e038c70882d23dfd9bd89a2 621 SUPERFAMILY SSF52540 357 600 2.5E-92 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1972 a4e6b2569e038c70882d23dfd9bd89a2 621 Pfam PF00005 ABC transporter 381 530 2.3E-36 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_2416 363b4734998e7d375954b5bc54c76134 328 SMART SM00342 234 317 4.3E-13 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Astex_2416 363b4734998e7d375954b5bc54c76134 328 SUPERFAMILY SSF46689 269 319 4.49E-8 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Astex_2416 363b4734998e7d375954b5bc54c76134 328 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 269 313 - T 13-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 Astex_2416 363b4734998e7d375954b5bc54c76134 328 Pfam PF12833 Helix-turn-helix domain 240 313 2.2E-12 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Astex_2416 363b4734998e7d375954b5bc54c76134 328 Gene3D G3DSA:1.10.10.60 215 327 1.3E-18 T 13-10-2018 Astex_1095 f4a9de6082682101ca45e87680dab8dd 93 SUPERFAMILY SSF55174 8 90 1.08E-13 T 13-10-2018 Astex_1095 f4a9de6082682101ca45e87680dab8dd 93 Gene3D G3DSA:3.10.290.10 1 93 2.3E-26 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 Astex_1595 5ecb479a4421fe19f501bf6809ab719d 447 Gene3D G3DSA:3.40.50.1820 26 320 3.2E-39 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1595 5ecb479a4421fe19f501bf6809ab719d 447 SUPERFAMILY SSF53474 27 310 2.4E-31 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1595 5ecb479a4421fe19f501bf6809ab719d 447 Pfam PF12146 Serine aminopeptidase, S33 48 304 7.7E-33 T 13-10-2018 IPR022742 Serine aminopeptidase, S33 Astex_1259 8042f80ebf4fbbd4e9ba37b550b47e69 769 Gene3D G3DSA:1.10.8.60 361 448 1.0E-31 T 13-10-2018 Astex_1259 8042f80ebf4fbbd4e9ba37b550b47e69 769 Gene3D G3DSA:3.40.50.300 449 661 6.2E-76 T 13-10-2018 Astex_1259 8042f80ebf4fbbd4e9ba37b550b47e69 769 SUPERFAMILY SSF52540 177 427 6.49E-69 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1259 8042f80ebf4fbbd4e9ba37b550b47e69 769 SMART SM00382 497 655 6.3E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_1259 8042f80ebf4fbbd4e9ba37b550b47e69 769 SMART SM00382 216 361 2.0E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_1259 8042f80ebf4fbbd4e9ba37b550b47e69 769 SUPERFAMILY SSF81923 4 143 2.49E-54 T 13-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 Astex_1259 8042f80ebf4fbbd4e9ba37b550b47e69 769 SUPERFAMILY SSF52540 447 750 1.54E-75 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1259 8042f80ebf4fbbd4e9ba37b550b47e69 769 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 528 546 - T 13-10-2018 IPR028299 ClpA/B, conserved site 2 Astex_1259 8042f80ebf4fbbd4e9ba37b550b47e69 769 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 18 64 6.3E-10 T 13-10-2018 IPR004176 Clp, N-terminal Astex_1259 8042f80ebf4fbbd4e9ba37b550b47e69 769 Pfam PF07724 AAA domain (Cdc48 subfamily) 496 657 2.2E-47 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Astex_1259 8042f80ebf4fbbd4e9ba37b550b47e69 769 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 501 519 7.8E-37 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 Astex_1259 8042f80ebf4fbbd4e9ba37b550b47e69 769 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 572 590 7.8E-37 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 Astex_1259 8042f80ebf4fbbd4e9ba37b550b47e69 769 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 605 619 7.8E-37 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 Astex_1259 8042f80ebf4fbbd4e9ba37b550b47e69 769 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 543 561 7.8E-37 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 Astex_1259 8042f80ebf4fbbd4e9ba37b550b47e69 769 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 663 742 1.6E-23 T 13-10-2018 IPR019489 Clp ATPase, C-terminal Astex_1259 8042f80ebf4fbbd4e9ba37b550b47e69 769 Gene3D G3DSA:3.40.50.300 166 360 4.0E-66 T 13-10-2018 Astex_1259 8042f80ebf4fbbd4e9ba37b550b47e69 769 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 221 322 3.8E-13 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Astex_1259 8042f80ebf4fbbd4e9ba37b550b47e69 769 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 312 324 - T 13-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 Astex_1259 8042f80ebf4fbbd4e9ba37b550b47e69 769 SMART SM01086 663 752 3.5E-34 T 13-10-2018 IPR019489 Clp ATPase, C-terminal Astex_1259 8042f80ebf4fbbd4e9ba37b550b47e69 769 TIGRFAM TIGR02639 ClpA: ATP-dependent Clp protease ATP-binding subunit ClpA 5 744 0.0 T 13-10-2018 IPR013461 ATP-dependent Clp protease ATP-binding subunit ClpA GO:0016887|GO:0043335 Astex_1259 8042f80ebf4fbbd4e9ba37b550b47e69 769 Gene3D G3DSA:1.10.8.60 663 767 1.0E-29 T 13-10-2018 Astex_1259 8042f80ebf4fbbd4e9ba37b550b47e69 769 Gene3D G3DSA:1.10.1780.10 4 144 1.1E-37 T 13-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 Astex_3239 c08cd5cd76417faebc49db839ad835c0 709 Gene3D G3DSA:1.10.1380.10 107 494 8.4E-227 T 13-10-2018 Astex_3239 c08cd5cd76417faebc49db839ad835c0 709 Pfam PF01431 Peptidase family M13 507 703 2.3E-63 T 13-10-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 Astex_3239 c08cd5cd76417faebc49db839ad835c0 709 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 538 554 7.5E-22 T 13-10-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 Astex_3239 c08cd5cd76417faebc49db839ad835c0 709 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 609 620 7.5E-22 T 13-10-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 Astex_3239 c08cd5cd76417faebc49db839ad835c0 709 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 499 511 7.5E-22 T 13-10-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 Astex_3239 c08cd5cd76417faebc49db839ad835c0 709 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 517 529 7.5E-22 T 13-10-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 Astex_3239 c08cd5cd76417faebc49db839ad835c0 709 Pfam PF05649 Peptidase family M13 81 455 3.6E-93 T 13-10-2018 IPR008753 Peptidase M13, N-terminal domain GO:0006508 Astex_3239 c08cd5cd76417faebc49db839ad835c0 709 Gene3D G3DSA:3.40.390.10 76 709 8.4E-227 T 13-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 Astex_3239 c08cd5cd76417faebc49db839ad835c0 709 SUPERFAMILY SSF55486 68 709 3.66E-198 T 13-10-2018 Astex_1720 cc78abb5db39cdb47aef35cd6483c9a9 74 Pfam PF01197 Ribosomal protein L31 1 69 2.2E-23 T 13-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_1720 cc78abb5db39cdb47aef35cd6483c9a9 74 ProSitePatterns PS01143 Ribosomal protein L31 signature. 38 60 - T 13-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_1720 cc78abb5db39cdb47aef35cd6483c9a9 74 PRINTS PR01249 Ribosomal protein L31 signature 2 19 1.9E-6 T 13-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_1720 cc78abb5db39cdb47aef35cd6483c9a9 74 PRINTS PR01249 Ribosomal protein L31 signature 50 68 1.9E-6 T 13-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_1720 cc78abb5db39cdb47aef35cd6483c9a9 74 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 70 3.4E-29 T 13-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_1720 cc78abb5db39cdb47aef35cd6483c9a9 74 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 72 25.911 T 13-10-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_1720 cc78abb5db39cdb47aef35cd6483c9a9 74 Gene3D G3DSA:2.30.170.50 1 74 2.8E-20 T 13-10-2018 Astex_1720 cc78abb5db39cdb47aef35cd6483c9a9 74 SUPERFAMILY SSF143800 1 71 2.35E-20 T 13-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_2600 1e92e5796ec0307c340131e7f33ad164 115 SUPERFAMILY SSF50022 13 114 1.44E-30 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 Astex_2600 1e92e5796ec0307c340131e7f33ad164 115 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 13 112 8.5E-24 T 13-10-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 Astex_2600 1e92e5796ec0307c340131e7f33ad164 115 Gene3D G3DSA:2.102.10.10 12 114 3.5E-27 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 Astex_2600 1e92e5796ec0307c340131e7f33ad164 115 Pfam PF00355 Rieske [2Fe-2S] domain 13 93 1.4E-16 T 13-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Astex_0393 653bb1f37f1c6f04443271ce3a66d5de 336 Gene3D G3DSA:3.90.850.10 125 325 3.5E-9 T 13-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 Astex_0393 653bb1f37f1c6f04443271ce3a66d5de 336 PIRSF PIRSF033905 2 336 1.8E-164 T 13-10-2018 IPR009645 Uncharacterised conserved protein GguC Astex_0393 653bb1f37f1c6f04443271ce3a66d5de 336 SUPERFAMILY SSF56529 121 321 1.98E-16 T 13-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 Astex_2004 653bb1f37f1c6f04443271ce3a66d5de 336 Gene3D G3DSA:3.90.850.10 125 325 3.5E-9 T 13-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 Astex_2004 653bb1f37f1c6f04443271ce3a66d5de 336 PIRSF PIRSF033905 2 336 1.8E-164 T 13-10-2018 IPR009645 Uncharacterised conserved protein GguC Astex_2004 653bb1f37f1c6f04443271ce3a66d5de 336 SUPERFAMILY SSF56529 121 321 1.98E-16 T 13-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 Astex_2076 7cb750dbaf1bb80d2a1710f4b69f4b71 65 Pfam PF12728 Helix-turn-helix domain 14 61 9.2E-8 T 13-10-2018 Astex_1812 4e1df0b8bdf804fe7434e9b3a90dc95c 160 Pfam PF13673 Acetyltransferase (GNAT) domain 33 138 1.5E-12 T 13-10-2018 IPR000182 GNAT domain Astex_1812 4e1df0b8bdf804fe7434e9b3a90dc95c 160 Gene3D G3DSA:3.40.630.30 2 149 2.3E-31 T 13-10-2018 Astex_1812 4e1df0b8bdf804fe7434e9b3a90dc95c 160 SUPERFAMILY SSF55729 4 160 6.8E-27 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Astex_0462 c58ec518407dab21ec17cbdfc55204f7 160 Gene3D G3DSA:1.20.120.1550 6 158 3.8E-9 T 13-10-2018 Astex_0462 c58ec518407dab21ec17cbdfc55204f7 160 Pfam PF16702 Domain of unknown function (DUF5063) 11 158 9.4E-8 T 13-10-2018 IPR032025 Protein of unknown function DUF5063 Astex_3608 2d10d222a15450e0ee941b40e2e9279b 298 SUPERFAMILY SSF56436 71 291 1.6E-51 T 13-10-2018 IPR016187 C-type lectin fold Astex_3608 2d10d222a15450e0ee941b40e2e9279b 298 Pfam PF03781 Sulfatase-modifying factor enzyme 1 72 289 4.7E-48 T 13-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 Astex_3608 2d10d222a15450e0ee941b40e2e9279b 298 Gene3D G3DSA:3.90.1580.10 61 297 5.3E-48 T 13-10-2018 Astex_0760 20ae3c46eb89245f73b9d8db63b3575a 255 Pfam PF06912 Protein of unknown function (DUF1275) 22 231 1.9E-33 T 13-10-2018 IPR010699 Protein of unknown function DUF1275 Astex_3096 e81f42e5e284b0bf9663e6924d3e5d17 232 Gene3D G3DSA:2.60.120.10 11 134 2.3E-77 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Astex_3096 e81f42e5e284b0bf9663e6924d3e5d17 232 SUPERFAMILY SSF51182 1 231 1.08E-70 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily Astex_3096 e81f42e5e284b0bf9663e6924d3e5d17 232 PIRSF PIRSF006232 2 232 1.2E-48 T 13-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 Astex_3096 e81f42e5e284b0bf9663e6924d3e5d17 232 Pfam PF02678 Pirin 14 118 4.4E-35 T 13-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 Astex_3096 e81f42e5e284b0bf9663e6924d3e5d17 232 Gene3D G3DSA:2.60.120.10 135 230 2.3E-77 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Astex_0123 6378e20bd35b34f01bc97eddd3962009 560 SUPERFAMILY SSF103473 17 555 6.63E-61 T 13-10-2018 IPR036259 MFS transporter superfamily Astex_0123 6378e20bd35b34f01bc97eddd3962009 560 ProSitePatterns PS00217 Sugar transport proteins signature 2. 129 154 - T 13-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 Astex_0123 6378e20bd35b34f01bc97eddd3962009 560 Pfam PF00083 Sugar (and other) transporter 451 555 1.4E-6 T 13-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 Astex_0123 6378e20bd35b34f01bc97eddd3962009 560 Pfam PF00083 Sugar (and other) transporter 229 328 3.0E-5 T 13-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 Astex_0123 6378e20bd35b34f01bc97eddd3962009 560 Pfam PF00083 Sugar (and other) transporter 22 225 1.9E-28 T 13-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 Astex_0123 6378e20bd35b34f01bc97eddd3962009 560 Gene3D G3DSA:1.20.1250.20 426 558 2.1E-11 T 13-10-2018 Astex_0123 6378e20bd35b34f01bc97eddd3962009 560 Gene3D G3DSA:1.20.1250.20 17 354 8.6E-59 T 13-10-2018 Astex_1545 6d8817d69cd42bf23c3f2be639341aa7 41 Pfam PF00444 Ribosomal protein L36 1 41 1.1E-18 T 13-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_1545 6d8817d69cd42bf23c3f2be639341aa7 41 SUPERFAMILY SSF57840 1 41 4.71E-14 T 13-10-2018 IPR035977 Ribosomal protein L36 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_1545 6d8817d69cd42bf23c3f2be639341aa7 41 ProSitePatterns PS00828 Ribosomal protein L36 signature. 14 40 - T 13-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_1545 6d8817d69cd42bf23c3f2be639341aa7 41 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 15 41 6.0E-4 T 13-10-2018 Astex_1545 6d8817d69cd42bf23c3f2be639341aa7 41 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 41 7.1E-11 T 13-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_1545 6d8817d69cd42bf23c3f2be639341aa7 41 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 41 17.15 T 13-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_3845 1b53898cf06df39ee32d19481d81d0b2 134 Gene3D G3DSA:2.40.50.320 63 134 1.3E-23 T 13-10-2018 Astex_3845 1b53898cf06df39ee32d19481d81d0b2 134 Pfam PF11604 Copper binding periplasmic protein CusF 69 134 1.1E-23 T 13-10-2018 IPR021647 Copper binding periplasmic protein CusF Astex_2257 2f5d01b15605fe9b14d4190c7bd796f0 436 SUPERFAMILY SSF48452 74 147 2.82E-5 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_2257 2f5d01b15605fe9b14d4190c7bd796f0 436 Gene3D G3DSA:1.25.40.10 19 174 1.8E-7 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_2257 2f5d01b15605fe9b14d4190c7bd796f0 436 Pfam PF04575 Protein of unknown function (DUF560) 151 436 1.6E-21 T 13-10-2018 IPR007655 Protein of unknown function DUF560 Astex_0163 40b18cad8400a08f31c2abde08e16c8c 147 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 14 142 2.1E-27 T 13-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 Astex_0163 40b18cad8400a08f31c2abde08e16c8c 147 Pfam PF00583 Acetyltransferase (GNAT) family 14 120 9.6E-16 T 13-10-2018 IPR000182 GNAT domain Astex_0163 40b18cad8400a08f31c2abde08e16c8c 147 SUPERFAMILY SSF55729 12 145 1.05E-28 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Astex_0163 40b18cad8400a08f31c2abde08e16c8c 147 Gene3D G3DSA:3.40.630.30 9 147 1.5E-34 T 13-10-2018 Astex_2481 c78fbabde10190b0c4af97391143e794 341 TIGRFAM TIGR02782 TrbB_P: P-type conjugative transfer ATPase TrbB 12 318 1.6E-116 T 13-10-2018 IPR014149 Conjugative transfer, TrbB GO:0000746|GO:0005737 Astex_2481 c78fbabde10190b0c4af97391143e794 341 Gene3D G3DSA:3.40.50.300 125 321 6.2E-54 T 13-10-2018 Astex_2481 c78fbabde10190b0c4af97391143e794 341 Gene3D G3DSA:3.30.450.90 18 124 3.2E-11 T 13-10-2018 Astex_2481 c78fbabde10190b0c4af97391143e794 341 SUPERFAMILY SSF52540 8 296 1.61E-38 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2481 c78fbabde10190b0c4af97391143e794 341 Pfam PF00437 Type II/IV secretion system protein 23 291 1.5E-81 T 13-10-2018 IPR001482 Type II/IV secretion system protein Astex_3013 1070b0446d3eed2fa7b2973dd2c1a9c6 351 Gene3D G3DSA:3.40.50.720 13 342 4.7E-127 T 13-10-2018 Astex_3013 1070b0446d3eed2fa7b2973dd2c1a9c6 351 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 12 126 3.3E-32 T 13-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 Astex_3013 1070b0446d3eed2fa7b2973dd2c1a9c6 351 Gene3D G3DSA:3.30.360.10 135 332 4.7E-127 T 13-10-2018 Astex_3013 1070b0446d3eed2fa7b2973dd2c1a9c6 351 PIRSF PIRSF000148 11 350 3.1E-110 T 13-10-2018 Astex_3013 1070b0446d3eed2fa7b2973dd2c1a9c6 351 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 146 331 1.9E-45 T 13-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Astex_3013 1070b0446d3eed2fa7b2973dd2c1a9c6 351 SMART SM00859 12 127 3.1E-39 T 13-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 Astex_3013 1070b0446d3eed2fa7b2973dd2c1a9c6 351 SUPERFAMILY SSF51735 12 164 8.01E-48 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_3013 1070b0446d3eed2fa7b2973dd2c1a9c6 351 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 248 262 - T 13-10-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 Astex_3013 1070b0446d3eed2fa7b2973dd2c1a9c6 351 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 10 345 33.768 T 13-10-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 Astex_3013 1070b0446d3eed2fa7b2973dd2c1a9c6 351 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 12 346 2.7E-127 T 13-10-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 Astex_3013 1070b0446d3eed2fa7b2973dd2c1a9c6 351 SUPERFAMILY SSF55347 136 332 7.44E-61 T 13-10-2018 Astex_0308 a0fd8f6b20f95202f81b3cd035c1a003 160 Hamap MF_00984 Single-stranded DNA-binding protein. 5 118 34.484 T 13-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 Astex_0308 a0fd8f6b20f95202f81b3cd035c1a003 160 Gene3D G3DSA:2.40.50.140 2 115 3.0E-46 T 13-10-2018 Astex_0308 a0fd8f6b20f95202f81b3cd035c1a003 160 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 3 160 4.0E-46 T 13-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 Astex_0308 a0fd8f6b20f95202f81b3cd035c1a003 160 SUPERFAMILY SSF50249 4 160 3.29E-47 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Astex_0308 a0fd8f6b20f95202f81b3cd035c1a003 160 Pfam PF00436 Single-strand binding protein family 5 107 1.9E-38 T 13-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 Astex_2248 6c07360f0ef8a94f7456c5f595167505 163 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 94 139 1.3E-14 T 13-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 Astex_2248 6c07360f0ef8a94f7456c5f595167505 163 Pfam PF12728 Helix-turn-helix domain 94 142 7.3E-11 T 13-10-2018 Astex_1685 1f302da09674aba9515e1f030e49ce61 205 Gene3D G3DSA:1.10.8.10 160 205 4.0E-8 T 13-10-2018 Astex_1685 1f302da09674aba9515e1f030e49ce61 205 Gene3D G3DSA:1.10.150.20 66 135 1.2E-20 T 13-10-2018 Astex_1685 1f302da09674aba9515e1f030e49ce61 205 Gene3D G3DSA:2.40.50.140 1 65 1.3E-19 T 13-10-2018 Astex_1685 1f302da09674aba9515e1f030e49ce61 205 Pfam PF07499 RuvA, C-terminal domain 158 203 3.9E-7 T 13-10-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 Astex_1685 1f302da09674aba9515e1f030e49ce61 205 SUPERFAMILY SSF50249 1 63 3.37E-14 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold Astex_1685 1f302da09674aba9515e1f030e49ce61 205 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 196 2.5E-35 T 13-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 Astex_1685 1f302da09674aba9515e1f030e49ce61 205 SUPERFAMILY SSF46929 159 204 1.1E-5 T 13-10-2018 IPR036267 RuvA, C-terminal domain superfamily Astex_1685 1f302da09674aba9515e1f030e49ce61 205 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 204 27.54 T 13-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 Astex_1685 1f302da09674aba9515e1f030e49ce61 205 Pfam PF01330 RuvA N terminal domain 1 62 1.1E-15 T 13-10-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 Astex_1685 1f302da09674aba9515e1f030e49ce61 205 SUPERFAMILY SSF47781 65 133 1.81E-18 T 13-10-2018 IPR010994 RuvA domain 2-like Astex_1685 1f302da09674aba9515e1f030e49ce61 205 Pfam PF14520 Helix-hairpin-helix domain 72 129 7.0E-12 T 13-10-2018 Astex_0149 d71a0fba10e95051035a4899c3ff05d8 199 SUPERFAMILY SSF52972 4 193 5.82E-44 T 13-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like Astex_0149 d71a0fba10e95051035a4899c3ff05d8 199 PIRSF PIRSF006305 1 198 4.2E-39 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 Astex_0149 d71a0fba10e95051035a4899c3ff05d8 199 Hamap MF_00528 Septum formation protein Maf [maf]. 5 198 24.3 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 Astex_0149 d71a0fba10e95051035a4899c3ff05d8 199 Gene3D G3DSA:3.90.950.10 2 197 1.1E-46 T 13-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like Astex_0149 d71a0fba10e95051035a4899c3ff05d8 199 Pfam PF02545 Maf-like protein 6 192 4.1E-38 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 Astex_2250 fe8a115352cd7508fc1e3e5485404e42 488 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 28 487 6.1E-143 T 13-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 Astex_2250 fe8a115352cd7508fc1e3e5485404e42 488 SMART SM00996 28 487 0.0 T 13-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 Astex_2250 fe8a115352cd7508fc1e3e5485404e42 488 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 100 114 - T 13-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 Astex_2250 fe8a115352cd7508fc1e3e5485404e42 488 SUPERFAMILY SSF52283 26 488 4.36E-115 T 13-10-2018 Astex_2250 fe8a115352cd7508fc1e3e5485404e42 488 SMART SM00997 249 408 3.9E-112 T 13-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 Astex_2250 fe8a115352cd7508fc1e3e5485404e42 488 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 271 288 - T 13-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 Astex_2250 fe8a115352cd7508fc1e3e5485404e42 488 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 29 480 8.5E-180 T 13-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 Astex_2250 fe8a115352cd7508fc1e3e5485404e42 488 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 249 408 2.5E-82 T 13-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 Astex_2250 fe8a115352cd7508fc1e3e5485404e42 488 SUPERFAMILY SSF51735 249 408 1.34E-76 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_2250 fe8a115352cd7508fc1e3e5485404e42 488 Gene3D G3DSA:3.40.50.1480 29 488 2.3E-236 T 13-10-2018 Astex_2250 fe8a115352cd7508fc1e3e5485404e42 488 PIRSF PIRSF001109 15 488 3.4E-188 T 13-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 Astex_2250 fe8a115352cd7508fc1e3e5485404e42 488 Gene3D G3DSA:3.40.50.720 251 408 2.3E-236 T 13-10-2018 Astex_2250 fe8a115352cd7508fc1e3e5485404e42 488 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 24 480 48.143 T 13-10-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508|Reactome: R-HSA-5578997 Astex_1362 6592e6902ab067edacc9e4b2b2d39530 222 TIGRFAM TIGR04123 P_estr_lig_assc: metallophosphoesterase, DNA ligase-associated 8 207 2.5E-63 T 13-10-2018 IPR026336 Metallophosphoesterase, DNA ligase-associated Astex_1362 6592e6902ab067edacc9e4b2b2d39530 222 PIRSF PIRSF000887 7 217 2.2E-43 T 13-10-2018 IPR024173 Phosphoesterase, MJ0037 Astex_1362 6592e6902ab067edacc9e4b2b2d39530 222 Pfam PF00149 Calcineurin-like phosphoesterase 28 143 2.7E-5 T 13-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 Astex_1362 6592e6902ab067edacc9e4b2b2d39530 222 Gene3D G3DSA:3.60.21.10 28 194 1.4E-6 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like Astex_1362 6592e6902ab067edacc9e4b2b2d39530 222 SUPERFAMILY SSF56300 28 131 2.71E-10 T 13-10-2018 Astex_2358 43db0c7d07966ceefc97231a56b677fe 312 Gene3D G3DSA:3.90.226.10 50 310 3.8E-71 T 13-10-2018 Astex_2358 43db0c7d07966ceefc97231a56b677fe 312 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 253 264 4.2E-36 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Astex_2358 43db0c7d07966ceefc97231a56b677fe 312 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 275 284 4.2E-36 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Astex_2358 43db0c7d07966ceefc97231a56b677fe 312 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 224 241 4.2E-36 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Astex_2358 43db0c7d07966ceefc97231a56b677fe 312 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 153 167 4.2E-36 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Astex_2358 43db0c7d07966ceefc97231a56b677fe 312 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 187 205 4.2E-36 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Astex_2358 43db0c7d07966ceefc97231a56b677fe 312 SUPERFAMILY SSF52096 50 307 1.14E-72 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Astex_2358 43db0c7d07966ceefc97231a56b677fe 312 Pfam PF01039 Carboxyl transferase domain 116 264 2.6E-19 T 13-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 Astex_2358 43db0c7d07966ceefc97231a56b677fe 312 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 38 305 33.934 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Astex_3115 67270ae845f5c2a4167443771f6996b6 309 SUPERFAMILY SSF46785 229 300 1.5E-19 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_3115 67270ae845f5c2a4167443771f6996b6 309 SUPERFAMILY SSF55811 11 145 3.32E-6 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 Astex_3115 67270ae845f5c2a4167443771f6996b6 309 PIRSF PIRSF019423 1 309 9.0E-110 T 13-10-2018 IPR011213 Nicotinic acid mononucleotide biosynthesis protein Astex_3115 67270ae845f5c2a4167443771f6996b6 309 Gene3D G3DSA:1.10.10.10 225 300 5.1E-23 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1089 3b16077a21c1fe9df06bb594cdec4006 98 Pfam PF00830 Ribosomal L28 family 3 60 2.3E-20 T 13-10-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_1089 3b16077a21c1fe9df06bb594cdec4006 98 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 58 1.7E-19 T 13-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_1089 3b16077a21c1fe9df06bb594cdec4006 98 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 68 18.416 T 13-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_1089 3b16077a21c1fe9df06bb594cdec4006 98 Gene3D G3DSA:2.30.170.40 2 77 1.1E-21 T 13-10-2018 IPR037147 Ribosomal protein L28/L24 superfamily GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_1089 3b16077a21c1fe9df06bb594cdec4006 98 SUPERFAMILY SSF143800 1 85 5.49E-23 T 13-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_2979 db46f6ff997f5344e8d5c6e2ef408eff 264 SUPERFAMILY SSF75217 104 261 5.36E-40 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases Astex_2979 db46f6ff997f5344e8d5c6e2ef408eff 264 Gene3D G3DSA:3.40.1280.10 114 263 6.9E-46 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Astex_2979 db46f6ff997f5344e8d5c6e2ef408eff 264 SMART SM00967 33 109 7.7E-8 T 13-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 Astex_2979 db46f6ff997f5344e8d5c6e2ef408eff 264 SUPERFAMILY SSF55315 4 105 1.41E-21 T 13-10-2018 IPR029064 50S ribosomal protein L30e-like Astex_2979 db46f6ff997f5344e8d5c6e2ef408eff 264 Gene3D G3DSA:3.30.1330.30 4 106 1.9E-26 T 13-10-2018 IPR029064 50S ribosomal protein L30e-like Astex_2979 db46f6ff997f5344e8d5c6e2ef408eff 264 Pfam PF00588 SpoU rRNA Methylase family 120 259 7.0E-34 T 13-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 Astex_2979 db46f6ff997f5344e8d5c6e2ef408eff 264 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 33 105 8.2E-8 T 13-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 Astex_3724 58224fb1f6b7e3525206e85c266130ba 626 PRINTS PR00811 Bacterial general secretion pathway protein D signature 428 452 1.4E-16 T 13-10-2018 IPR001775 GspD/PilQ family Astex_3724 58224fb1f6b7e3525206e85c266130ba 626 PRINTS PR00811 Bacterial general secretion pathway protein D signature 585 599 1.4E-16 T 13-10-2018 IPR001775 GspD/PilQ family Astex_3724 58224fb1f6b7e3525206e85c266130ba 626 PRINTS PR00811 Bacterial general secretion pathway protein D signature 562 580 1.4E-16 T 13-10-2018 IPR001775 GspD/PilQ family Astex_3724 58224fb1f6b7e3525206e85c266130ba 626 PRINTS PR00811 Bacterial general secretion pathway protein D signature 369 379 1.4E-16 T 13-10-2018 IPR001775 GspD/PilQ family Astex_3724 58224fb1f6b7e3525206e85c266130ba 626 Gene3D G3DSA:3.55.50.30 33 127 6.3E-15 T 13-10-2018 Astex_3724 58224fb1f6b7e3525206e85c266130ba 626 TIGRFAM TIGR02517 type_II_gspD: type II secretion system protein D 42 604 4.2E-112 T 13-10-2018 IPR013356 Type II secretion system GspD GO:0008565|GO:0015627|GO:0015628|GO:0019867 Astex_3724 58224fb1f6b7e3525206e85c266130ba 626 Gene3D G3DSA:3.30.1370.120 199 266 1.9E-5 T 13-10-2018 IPR038591 NolW-like superfamily Astex_3724 58224fb1f6b7e3525206e85c266130ba 626 Gene3D G3DSA:3.30.1370.120 135 196 2.0E-5 T 13-10-2018 IPR038591 NolW-like superfamily Astex_3724 58224fb1f6b7e3525206e85c266130ba 626 Pfam PF03958 Bacterial type II/III secretion system short domain 275 369 6.0E-13 T 13-10-2018 IPR005644 NolW-like Astex_3724 58224fb1f6b7e3525206e85c266130ba 626 Pfam PF00263 Bacterial type II and III secretion system protein 432 598 2.1E-45 T 13-10-2018 IPR004846 Type II/III secretion system GO:0009306 Astex_2415 6f1f9b79f7c9b556fc77135f4204853c 114 Pfam PF11776 Nickel/cobalt transporter regulator 67 108 4.2E-11 T 13-10-2018 IPR024572 Nickel/cobalt homeostasis protein RcnB Astex_2415 6f1f9b79f7c9b556fc77135f4204853c 114 Gene3D G3DSA:3.10.450.160 41 114 1.5E-9 T 13-10-2018 Astex_0552 c913f8037563473d49cf20fd7391f5b6 228 Pfam PF00857 Isochorismatase family 14 164 1.3E-22 T 13-10-2018 IPR000868 Isochorismatase-like GO:0003824 Astex_0552 c913f8037563473d49cf20fd7391f5b6 228 SUPERFAMILY SSF52499 8 205 1.57E-44 T 13-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 Astex_0552 c913f8037563473d49cf20fd7391f5b6 228 Gene3D G3DSA:3.40.50.850 4 206 4.0E-44 T 13-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 Astex_1389 bd8f292d61b9df8c4a18d32ff396187e 159 SUPERFAMILY SSF88946 8 82 5.89E-7 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 Astex_1389 bd8f292d61b9df8c4a18d32ff396187e 159 Gene3D G3DSA:1.10.10.10 83 157 1.3E-12 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1389 bd8f292d61b9df8c4a18d32ff396187e 159 Pfam PF04542 Sigma-70 region 2 7 69 7.4E-7 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 Astex_1389 bd8f292d61b9df8c4a18d32ff396187e 159 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 3 151 4.6E-18 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 Astex_1389 bd8f292d61b9df8c4a18d32ff396187e 159 SUPERFAMILY SSF88659 83 155 1.55E-13 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Astex_1389 bd8f292d61b9df8c4a18d32ff396187e 159 Pfam PF08281 Sigma-70, region 4 102 148 1.9E-11 T 13-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Astex_1330 0cc5fae353d5069038576d2b493f9386 365 Gene3D G3DSA:1.10.1200.160 313 342 1.9E-52 T 13-10-2018 Astex_1330 0cc5fae353d5069038576d2b493f9386 365 Pfam PF03743 Bacterial conjugation TrbI-like protein 191 363 1.2E-53 T 13-10-2018 IPR005498 Type IV secretion system, VirB10 / TraB / TrbI Astex_1330 0cc5fae353d5069038576d2b493f9386 365 Gene3D G3DSA:2.40.128.260 194 361 1.9E-52 T 13-10-2018 Astex_1952 171077c7c443c20de406efdc8952285c 605 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 158 168 - T 13-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Astex_1952 171077c7c443c20de406efdc8952285c 605 TIGRFAM TIGR01196 edd: phosphogluconate dehydratase 6 604 2.9E-273 T 13-10-2018 IPR004786 6-phosphogluconate dehydratase GO:0004456|GO:0009255 KEGG: 00030+4.2.1.12 Astex_1952 171077c7c443c20de406efdc8952285c 605 SUPERFAMILY SSF143975 5 422 2.75E-138 T 13-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Astex_1952 171077c7c443c20de406efdc8952285c 605 SUPERFAMILY SSF52016 423 603 5.26E-51 T 13-10-2018 Astex_1952 171077c7c443c20de406efdc8952285c 605 Gene3D G3DSA:3.50.30.80 423 573 6.5E-46 T 13-10-2018 Astex_1952 171077c7c443c20de406efdc8952285c 605 Pfam PF00920 Dehydratase family 70 600 8.9E-151 T 13-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 Astex_1952 171077c7c443c20de406efdc8952285c 605 Hamap MF_02094 Phosphogluconate dehydratase [edd]. 5 605 54.14 T 13-10-2018 Astex_2695 bef26901af35aa0555816919c8fd4314 273 Gene3D G3DSA:3.20.20.60 10 273 1.8E-99 T 13-10-2018 Astex_2695 bef26901af35aa0555816919c8fd4314 273 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 19 270 2.8E-92 T 13-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 Astex_2695 bef26901af35aa0555816919c8fd4314 273 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 12 270 39.383 T 13-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 Astex_2695 bef26901af35aa0555816919c8fd4314 273 Pfam PF02548 Ketopantoate hydroxymethyltransferase 13 265 5.4E-102 T 13-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 Astex_2695 bef26901af35aa0555816919c8fd4314 273 PIRSF PIRSF000388 2 273 6.6E-101 T 13-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 Astex_2695 bef26901af35aa0555816919c8fd4314 273 SUPERFAMILY SSF51621 12 270 1.44E-94 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 Astex_1642 a1bb4d07902f5d7e03b0b917dd910b26 109 Pfam PF05164 Cell division protein ZapA 4 105 3.1E-18 T 13-10-2018 IPR007838 Cell division protein ZapA-like Astex_1642 a1bb4d07902f5d7e03b0b917dd910b26 109 SUPERFAMILY SSF102829 4 80 2.62E-15 T 13-10-2018 IPR036192 Cell division protein ZapA-like superfamily Astex_2821 b3e41f3b14305f925352c7c9a25bf8ea 677 Pfam PF07167 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus 182 354 5.7E-72 T 13-10-2018 IPR010941 Poly-beta-hydroxybutyrate polymerase, N-terminal domain GO:0042619 Astex_2821 b3e41f3b14305f925352c7c9a25bf8ea 677 Gene3D G3DSA:3.40.50.1820 342 611 6.2E-10 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_2821 b3e41f3b14305f925352c7c9a25bf8ea 677 SUPERFAMILY SSF53474 313 611 2.92E-37 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_2821 b3e41f3b14305f925352c7c9a25bf8ea 677 TIGRFAM TIGR01838 PHA_synth_I: poly(R)-hydroxyalkanoic acid synthase, class I 142 674 4.7E-221 T 13-10-2018 IPR010963 Poly(R)-hydroxyalkanoic acid synthase, class I GO:0005737|GO:0016746|GO:0042619 Astex_0814 b1fca28bec0113ba898086e5e68e6adf 243 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 242 31.69 T 13-10-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 Astex_0814 b1fca28bec0113ba898086e5e68e6adf 243 SUPERFAMILY SSF51366 1 240 1.14E-55 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Astex_0814 b1fca28bec0113ba898086e5e68e6adf 243 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 3 238 3.4E-71 T 13-10-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 Astex_0814 b1fca28bec0113ba898086e5e68e6adf 243 Pfam PF00977 Histidine biosynthesis protein 3 234 1.5E-65 T 13-10-2018 IPR006062 Histidine biosynthesis GO:0000105 Astex_0814 b1fca28bec0113ba898086e5e68e6adf 243 Gene3D G3DSA:3.20.20.70 2 243 3.4E-79 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_1205 bd9d36f2d8126c487f2c38eb348e5d73 544 Pfam PF01523 Putative modulator of DNA gyrase 59 385 5.3E-60 T 13-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 Astex_1205 bd9d36f2d8126c487f2c38eb348e5d73 544 SUPERFAMILY SSF111283 42 537 4.84E-91 T 13-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 Astex_1205 bd9d36f2d8126c487f2c38eb348e5d73 544 Gene3D G3DSA:3.30.2290.10 27 233 3.5E-16 T 13-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal Astex_0640 e9287d307db6591a10e58555c171e008 714 Gene3D G3DSA:2.115.10.20 44 357 1.5E-73 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Astex_0640 e9287d307db6591a10e58555c171e008 714 SUPERFAMILY SSF49899 377 564 4.75E-40 T 13-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily Astex_0640 e9287d307db6591a10e58555c171e008 714 Pfam PF04616 Glycosyl hydrolases family 43 50 257 3.3E-38 T 13-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 Astex_0640 e9287d307db6591a10e58555c171e008 714 SUPERFAMILY SSF75005 50 355 1.23E-64 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Astex_0640 e9287d307db6591a10e58555c171e008 714 Gene3D G3DSA:2.60.120.200 374 563 2.3E-53 T 13-10-2018 Astex_2319 4c985904dcfacd070fe16d9e64b1348e 231 SUPERFAMILY SSF46894 128 228 5.83E-31 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Astex_2319 4c985904dcfacd070fe16d9e64b1348e 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 227 9.3E-28 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Astex_2319 4c985904dcfacd070fe16d9e64b1348e 231 Gene3D G3DSA:1.10.10.10 131 229 6.7E-34 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_2319 4c985904dcfacd070fe16d9e64b1348e 231 SMART SM00862 152 227 6.2E-27 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Astex_2319 4c985904dcfacd070fe16d9e64b1348e 231 SMART SM00448 5 118 6.4E-45 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_2319 4c985904dcfacd070fe16d9e64b1348e 231 SUPERFAMILY SSF52172 4 127 5.69E-42 T 13-10-2018 IPR011006 CheY-like superfamily Astex_2319 4c985904dcfacd070fe16d9e64b1348e 231 TIGRFAM TIGR02154 PhoB: phosphate regulon transcriptional regulatory protein PhoB 5 228 1.4E-105 T 13-10-2018 IPR011879 Signal transduction response regulator, phosphate regulon transcriptional regulatory protein PhoB GO:0000156|GO:0000160|GO:0003677|GO:0006817 Astex_2319 4c985904dcfacd070fe16d9e64b1348e 231 Gene3D G3DSA:3.40.50.2300 3 130 3.0E-38 T 13-10-2018 Astex_2319 4c985904dcfacd070fe16d9e64b1348e 231 Pfam PF00072 Response regulator receiver domain 7 119 8.2E-30 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_0688 605a5dcb94ff87e2a2b9f1641fc1bef5 548 Gene3D G3DSA:3.40.630.10 247 527 8.5E-51 T 13-10-2018 Astex_0688 605a5dcb94ff87e2a2b9f1641fc1bef5 548 SUPERFAMILY SSF52025 129 213 9.55E-11 T 13-10-2018 Astex_0688 605a5dcb94ff87e2a2b9f1641fc1bef5 548 SUPERFAMILY SSF53187 28 526 6.51E-61 T 13-10-2018 Astex_0688 605a5dcb94ff87e2a2b9f1641fc1bef5 548 Pfam PF02225 PA domain 130 221 1.4E-9 T 13-10-2018 IPR003137 PA domain Astex_0688 605a5dcb94ff87e2a2b9f1641fc1bef5 548 Pfam PF04389 Peptidase family M28 297 514 1.7E-47 T 13-10-2018 IPR007484 Peptidase M28 Astex_0688 605a5dcb94ff87e2a2b9f1641fc1bef5 548 Gene3D G3DSA:3.50.30.30 112 233 4.0E-5 T 13-10-2018 Astex_0665 81e9453dca7680a7e219a41c026003e2 190 SUPERFAMILY SSF50630 75 177 1.49E-16 T 13-10-2018 IPR021109 Aspartic peptidase domain superfamily Astex_0665 81e9453dca7680a7e219a41c026003e2 190 Pfam PF13975 gag-polyprotein putative aspartyl protease 85 175 1.7E-24 T 13-10-2018 Astex_0665 81e9453dca7680a7e219a41c026003e2 190 ProSitePatterns PS00141 Eukaryotic and viral aspartyl proteases active site. 95 106 - T 13-10-2018 IPR001969 Aspartic peptidase, active site GO:0004190|GO:0006508 Astex_0665 81e9453dca7680a7e219a41c026003e2 190 TIGRFAM TIGR02281 clan_AA_DTGA: clan AA aspartic protease, TIGR02281 family 73 189 3.8E-43 T 13-10-2018 IPR011969 Clan AA aspartic peptidase, C-terminal Astex_0665 81e9453dca7680a7e219a41c026003e2 190 Gene3D G3DSA:2.40.70.10 47 189 5.0E-35 T 13-10-2018 IPR021109 Aspartic peptidase domain superfamily Astex_1189 65e8bb70db2830117f08e82ae32bad81 433 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 414 3.3E-100 T 13-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 Astex_1189 65e8bb70db2830117f08e82ae32bad81 433 Gene3D G3DSA:3.65.10.10 7 421 4.2E-158 T 13-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 Astex_1189 65e8bb70db2830117f08e82ae32bad81 433 SUPERFAMILY SSF55205 1 425 3.27E-134 T 13-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 Astex_1189 65e8bb70db2830117f08e82ae32bad81 433 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 424 41.767 T 13-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Astex_1189 65e8bb70db2830117f08e82ae32bad81 433 Gene3D G3DSA:3.65.10.10 21 235 4.2E-158 T 13-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 Astex_1189 65e8bb70db2830117f08e82ae32bad81 433 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 423 6.1E-165 T 13-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 Astex_3399 b83e6f73dfbe3382406dae0f52c0fd88 393 Pfam PF00557 Metallopeptidase family M24 171 377 5.9E-52 T 13-10-2018 IPR000994 Peptidase M24 Astex_3399 b83e6f73dfbe3382406dae0f52c0fd88 393 Gene3D G3DSA:3.90.230.10 162 392 1.4E-71 T 13-10-2018 Astex_3399 b83e6f73dfbe3382406dae0f52c0fd88 393 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 323 335 - T 13-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site Astex_3399 b83e6f73dfbe3382406dae0f52c0fd88 393 SUPERFAMILY SSF55920 162 386 1.44E-64 T 13-10-2018 IPR036005 Creatinase/aminopeptidase-like Astex_3399 b83e6f73dfbe3382406dae0f52c0fd88 393 Pfam PF01321 Creatinase/Prolidase N-terminal domain 32 162 2.3E-12 T 13-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 Astex_3399 b83e6f73dfbe3382406dae0f52c0fd88 393 SUPERFAMILY SSF53092 18 162 4.71E-15 T 13-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal Astex_3399 b83e6f73dfbe3382406dae0f52c0fd88 393 Gene3D G3DSA:3.40.350.10 1 161 3.3E-36 T 13-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal Astex_3702 3a7a7cfe257bc904714a6f5cfd26c99f 186 Gene3D G3DSA:1.10.1740.10 6 91 1.7E-17 T 13-10-2018 Astex_3702 3a7a7cfe257bc904714a6f5cfd26c99f 186 Gene3D G3DSA:1.10.10.10 100 177 3.1E-14 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_3702 3a7a7cfe257bc904714a6f5cfd26c99f 186 SUPERFAMILY SSF88659 117 175 1.14E-11 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Astex_3702 3a7a7cfe257bc904714a6f5cfd26c99f 186 Pfam PF08281 Sigma-70, region 4 120 172 3.7E-12 T 13-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Astex_3702 3a7a7cfe257bc904714a6f5cfd26c99f 186 Pfam PF04542 Sigma-70 region 2 27 93 4.1E-13 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 Astex_3702 3a7a7cfe257bc904714a6f5cfd26c99f 186 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 23 174 2.0E-22 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 Astex_3702 3a7a7cfe257bc904714a6f5cfd26c99f 186 SUPERFAMILY SSF88946 2 107 1.75E-22 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 Astex_0102 63c957b5645e0aa59c0ac164d57aa6af 180 SUPERFAMILY SSF56954 1 142 6.28E-5 T 13-10-2018 Astex_1001 cb6946c3285352cc2a7eecba2402879c 76 Pfam PF05532 CsbD-like 4 55 9.0E-19 T 13-10-2018 IPR008462 CsbD-like domain Astex_1001 cb6946c3285352cc2a7eecba2402879c 76 PIRSF PIRSF039008 1 66 4.7E-27 T 13-10-2018 IPR026042 Stress response protein YjbJ Astex_1001 cb6946c3285352cc2a7eecba2402879c 76 Gene3D G3DSA:1.10.1470.10 1 64 2.2E-26 T 13-10-2018 IPR036629 YjbJ superfamily Astex_1001 cb6946c3285352cc2a7eecba2402879c 76 SUPERFAMILY SSF69047 1 65 2.35E-22 T 13-10-2018 IPR036629 YjbJ superfamily Astex_2434 c54bf733d016930d4ea07449dcd2eab7 99 Pfam PF01381 Helix-turn-helix 12 64 8.9E-12 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Astex_2434 c54bf733d016930d4ea07449dcd2eab7 99 SMART SM00530 10 66 1.2E-7 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Astex_2434 c54bf733d016930d4ea07449dcd2eab7 99 SUPERFAMILY SSF47413 5 72 2.56E-14 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Astex_2434 c54bf733d016930d4ea07449dcd2eab7 99 Gene3D G3DSA:1.10.260.40 1 72 1.3E-17 T 13-10-2018 Astex_2285 182a8ca096caf60fd41a24a437adb57f 243 SUPERFAMILY SSF53448 1 240 3.99E-51 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_2285 182a8ca096caf60fd41a24a437adb57f 243 Hamap MF_00057 8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase [kdsB]. 1 241 32.721 T 13-10-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 Astex_2285 182a8ca096caf60fd41a24a437adb57f 243 Gene3D G3DSA:3.90.550.10 4 240 1.1E-72 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_2285 182a8ca096caf60fd41a24a437adb57f 243 Pfam PF02348 Cytidylyltransferase 4 215 9.4E-40 T 13-10-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 Astex_2285 182a8ca096caf60fd41a24a437adb57f 243 TIGRFAM TIGR00466 kdsB: 3-deoxy-D-manno-octulosonate cytidylyltransferase 3 234 1.5E-54 T 13-10-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 Astex_3517 416171a581de06dab615f95ecc2e17a8 239 SUPERFAMILY SSF52799 48 190 3.4E-20 T 13-10-2018 IPR029021 Protein-tyrosine phosphatase-like Astex_3517 416171a581de06dab615f95ecc2e17a8 239 Gene3D G3DSA:3.90.190.10 44 181 5.2E-21 T 13-10-2018 IPR029021 Protein-tyrosine phosphatase-like Astex_2443 8f200d1b3ab0b14703d3a1b6520c1399 850 Gene3D G3DSA:3.55.50.30 29 134 1.4E-18 T 13-10-2018 Astex_2443 8f200d1b3ab0b14703d3a1b6520c1399 850 Pfam PF00593 TonB dependent receptor 347 846 1.3E-41 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_2443 8f200d1b3ab0b14703d3a1b6520c1399 850 SUPERFAMILY SSF56935 123 846 6.59E-87 T 13-10-2018 Astex_2443 8f200d1b3ab0b14703d3a1b6520c1399 850 SMART SM00965 61 110 8.3E-6 T 13-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 Astex_2443 8f200d1b3ab0b14703d3a1b6520c1399 850 Pfam PF07715 TonB-dependent Receptor Plug Domain 136 254 9.7E-19 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_2443 8f200d1b3ab0b14703d3a1b6520c1399 850 Gene3D G3DSA:2.170.130.10 135 262 5.6E-29 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_1597 f54ef8f47e6d3b503650e50e250a4c93 161 Gene3D G3DSA:1.20.1260.10 1 158 6.9E-63 T 13-10-2018 IPR012347 Ferritin-like Astex_1597 f54ef8f47e6d3b503650e50e250a4c93 161 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 Astex_1597 f54ef8f47e6d3b503650e50e250a4c93 161 TIGRFAM TIGR00754 bfr: bacterioferritin 1 156 2.7E-67 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 Astex_1597 f54ef8f47e6d3b503650e50e250a4c93 161 Pfam PF00210 Ferritin-like domain 8 144 1.6E-34 T 13-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 Astex_1597 f54ef8f47e6d3b503650e50e250a4c93 161 PRINTS PR00601 Bacterioferritin signature 3 22 3.0E-59 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 Astex_1597 f54ef8f47e6d3b503650e50e250a4c93 161 PRINTS PR00601 Bacterioferritin signature 86 106 3.0E-59 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 Astex_1597 f54ef8f47e6d3b503650e50e250a4c93 161 PRINTS PR00601 Bacterioferritin signature 44 64 3.0E-59 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 Astex_1597 f54ef8f47e6d3b503650e50e250a4c93 161 PRINTS PR00601 Bacterioferritin signature 128 149 3.0E-59 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 Astex_1597 f54ef8f47e6d3b503650e50e250a4c93 161 PRINTS PR00601 Bacterioferritin signature 23 43 3.0E-59 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 Astex_1597 f54ef8f47e6d3b503650e50e250a4c93 161 PRINTS PR00601 Bacterioferritin signature 107 127 3.0E-59 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 Astex_1597 f54ef8f47e6d3b503650e50e250a4c93 161 PRINTS PR00601 Bacterioferritin signature 65 85 3.0E-59 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 Astex_1597 f54ef8f47e6d3b503650e50e250a4c93 161 SUPERFAMILY SSF47240 1 154 2.58E-49 T 13-10-2018 IPR009078 Ferritin-like superfamily Astex_1597 f54ef8f47e6d3b503650e50e250a4c93 161 PIRSF PIRSF002560 1 157 2.2E-67 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 Astex_2631 5369a14465e3acd6398c98ed6476c8b6 209 Gene3D G3DSA:2.10.109.10 83 208 5.5E-18 T 13-10-2018 Astex_2631 5369a14465e3acd6398c98ed6476c8b6 209 Pfam PF00717 Peptidase S24-like 126 187 2.0E-14 T 13-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C Astex_2631 5369a14465e3acd6398c98ed6476c8b6 209 SUPERFAMILY SSF51306 85 206 6.02E-23 T 13-10-2018 IPR036286 LexA/Signal peptidase-like superfamily Astex_3314 00115ee3d15572b101a0f865807219c6 294 SUPERFAMILY SSF53474 37 261 1.84E-13 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_3314 00115ee3d15572b101a0f865807219c6 294 Gene3D G3DSA:3.40.50.1820 11 294 2.3E-45 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_2947 b59e0d2d2dff563c8235853da4b907c9 407 Gene3D G3DSA:3.40.640.10 63 298 4.8E-166 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Astex_2947 b59e0d2d2dff563c8235853da4b907c9 407 TIGRFAM TIGR01821 5aminolev_synth: 5-aminolevulinic acid synthase 1 402 5.3E-200 T 13-10-2018 IPR010961 Tetrapyrrole biosynthesis, 5-aminolevulinic acid synthase GO:0003870|GO:0030170|GO:0033014 KEGG: 00260+2.3.1.37|KEGG: 00860+2.3.1.37|MetaCyc: PWY-5189|MetaCyc: PWY-7536|Reactome: R-HSA-189451 Astex_2947 b59e0d2d2dff563c8235853da4b907c9 407 SUPERFAMILY SSF53383 4 399 1.29E-112 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Astex_2947 b59e0d2d2dff563c8235853da4b907c9 407 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 245 254 - T 13-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 Astex_2947 b59e0d2d2dff563c8235853da4b907c9 407 Pfam PF00155 Aminotransferase class I and II 47 390 1.9E-80 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Astex_2947 b59e0d2d2dff563c8235853da4b907c9 407 Gene3D G3DSA:3.90.1150.10 15 388 4.8E-166 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Astex_0501 5ff2325286990f23496dac0772301012 392 Pfam PF04235 Protein of unknown function (DUF418) 233 386 4.1E-38 T 13-10-2018 IPR007349 Domain of unknown function DUF418 Astex_0658 1df81e0a390f4e92065dac6aaa1e5e53 569 PIRSF PIRSF001294 6 568 3.4E-246 T 13-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 Astex_0658 1df81e0a390f4e92065dac6aaa1e5e53 569 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 8 566 4.7E-245 T 13-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 Astex_0658 1df81e0a390f4e92065dac6aaa1e5e53 569 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 6 566 35.81 T 13-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 Astex_0658 1df81e0a390f4e92065dac6aaa1e5e53 569 Pfam PF03814 Potassium-transporting ATPase A subunit 15 564 6.6E-251 T 13-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 Astex_0478 25b2a5abb7c548c80af346e51f83d956 144 Pfam PF02566 OsmC-like protein 44 139 1.1E-19 T 13-10-2018 IPR003718 OsmC/Ohr family Astex_0478 25b2a5abb7c548c80af346e51f83d956 144 Gene3D G3DSA:3.30.300.20 1 143 1.4E-42 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta Astex_0478 25b2a5abb7c548c80af346e51f83d956 144 SUPERFAMILY SSF82784 2 139 3.01E-37 T 13-10-2018 IPR036102 OsmC/Ohr superfamily Astex_0478 25b2a5abb7c548c80af346e51f83d956 144 TIGRFAM TIGR03562 osmo_induc_OsmC: peroxiredoxin, OsmC subfamily 2 141 7.6E-56 T 13-10-2018 IPR019904 Peroxiredoxin OsmC GO:0004601|GO:0006979 KEGG: 00480+1.11.1.15 Astex_0155 dd242ba3cf3d7bf387cf9eb153339eac 404 Gene3D G3DSA:2.40.40.10 76 402 5.8E-95 T 13-10-2018 IPR036908 RlpA-like domain superfamily Astex_0155 dd242ba3cf3d7bf387cf9eb153339eac 404 PIRSF PIRSF019422 9 404 3.1E-91 T 13-10-2018 IPR026044 Membrane-bound lytic murein transglycosylase A Astex_0155 dd242ba3cf3d7bf387cf9eb153339eac 404 Pfam PF06725 3D domain 325 400 1.6E-20 T 13-10-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 Astex_0155 dd242ba3cf3d7bf387cf9eb153339eac 404 SMART SM00925 149 304 5.1E-46 T 13-10-2018 IPR005300 Lytic transglycosylase MltA, domain B GO:0004553 Astex_0155 dd242ba3cf3d7bf387cf9eb153339eac 404 SUPERFAMILY SSF50685 72 403 1.78E-93 T 13-10-2018 IPR036908 RlpA-like domain superfamily Astex_0155 dd242ba3cf3d7bf387cf9eb153339eac 404 Pfam PF03562 MltA specific insert domain 81 303 2.4E-54 T 13-10-2018 IPR005300 Lytic transglycosylase MltA, domain B GO:0004553 Astex_0155 dd242ba3cf3d7bf387cf9eb153339eac 404 Gene3D G3DSA:2.40.240.50 148 308 5.8E-95 T 13-10-2018 Astex_2159 a681fa057e34fd0c7c75d42bee9ece5c 451 SUPERFAMILY SSF52266 206 403 4.83E-45 T 13-10-2018 Astex_2159 a681fa057e34fd0c7c75d42bee9ece5c 451 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 212 390 1.5E-15 T 13-10-2018 IPR013830 SGNH hydrolase-type esterase domain Astex_2159 a681fa057e34fd0c7c75d42bee9ece5c 451 SUPERFAMILY SSF49785 63 203 2.3E-17 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_2159 a681fa057e34fd0c7c75d42bee9ece5c 451 Gene3D G3DSA:3.40.50.1110 206 414 1.9E-61 T 13-10-2018 IPR036514 SGNH hydrolase superfamily Astex_1083 3f98ebef585b68c1b7ebe75bbfa2f386 149 SUPERFAMILY SSF51316 3 129 3.98E-39 T 13-10-2018 IPR011057 Mss4-like superfamily Astex_1083 3f98ebef585b68c1b7ebe75bbfa2f386 149 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 27 109 1.3E-16 T 13-10-2018 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 Astex_1083 3f98ebef585b68c1b7ebe75bbfa2f386 149 Gene3D G3DSA:2.170.150.70 6 110 5.0E-13 T 13-10-2018 Astex_0742 719d2c6f141d3b3fca4f1ed85f8978cb 515 SUPERFAMILY SSF48452 87 298 6.96E-5 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_0742 719d2c6f141d3b3fca4f1ed85f8978cb 515 Pfam PF07219 HemY protein N-terminus 26 130 3.7E-21 T 13-10-2018 IPR010817 HemY, N-terminal Astex_0742 719d2c6f141d3b3fca4f1ed85f8978cb 515 Gene3D G3DSA:1.25.40.10 67 310 2.5E-5 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_1573 f752c0e9f338d1d95df6ce956bb51363 361 Gene3D G3DSA:3.30.1380.10 222 348 4.3E-20 T 13-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 Astex_1573 f752c0e9f338d1d95df6ce956bb51363 361 SUPERFAMILY SSF53955 2 204 1.1E-44 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily Astex_1573 f752c0e9f338d1d95df6ce956bb51363 361 SUPERFAMILY SSF55166 222 338 1.92E-23 T 13-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 Astex_1573 f752c0e9f338d1d95df6ce956bb51363 361 Gene3D G3DSA:1.10.530.70 12 204 3.5E-17 T 13-10-2018 Astex_1573 f752c0e9f338d1d95df6ce956bb51363 361 Pfam PF08291 Peptidase M15 222 334 6.5E-21 T 13-10-2018 IPR013230 Peptidase M15A, C-terminal KEGG: 00550+3.4.17.14|MetaCyc: PWY-6470 Astex_2764 ce007f04dbf6847255e78121eb6129ad 352 SUPERFAMILY SSF101960 7 344 7.98E-63 T 13-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily Astex_2764 ce007f04dbf6847255e78121eb6129ad 352 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 105 336 2.1E-66 T 13-10-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 Astex_2764 ce007f04dbf6847255e78121eb6129ad 352 Pfam PF01458 Uncharacterized protein family (UPF0051) 105 321 6.9E-56 T 13-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 Astex_1073 35ab9cd9bd0ac6eedd45fd69a9d93e60 283 SUPERFAMILY SSF51735 3 253 3.23E-53 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_1073 35ab9cd9bd0ac6eedd45fd69a9d93e60 283 Gene3D G3DSA:3.90.25.10 137 266 8.7E-79 T 13-10-2018 Astex_1073 35ab9cd9bd0ac6eedd45fd69a9d93e60 283 Pfam PF05368 NmrA-like family 4 216 8.7E-19 T 13-10-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 Astex_1073 35ab9cd9bd0ac6eedd45fd69a9d93e60 283 Gene3D G3DSA:3.40.50.720 5 265 8.7E-79 T 13-10-2018 Astex_1436 8ada720582a85548f7829bf69a6b2227 387 PRINTS PR00955 Flagellar motor switch protein FliM signature 263 281 7.5E-24 T 13-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 Astex_1436 8ada720582a85548f7829bf69a6b2227 387 PRINTS PR00955 Flagellar motor switch protein FliM signature 60 73 7.5E-24 T 13-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 Astex_1436 8ada720582a85548f7829bf69a6b2227 387 PRINTS PR00955 Flagellar motor switch protein FliM signature 164 183 7.5E-24 T 13-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 Astex_1436 8ada720582a85548f7829bf69a6b2227 387 PRINTS PR00955 Flagellar motor switch protein FliM signature 139 155 7.5E-24 T 13-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 Astex_1436 8ada720582a85548f7829bf69a6b2227 387 PIRSF PIRSF002888 14 382 1.5E-93 T 13-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 Astex_1436 8ada720582a85548f7829bf69a6b2227 387 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 303 372 1.7E-19 T 13-10-2018 IPR001543 Surface presentation of antigen (SpoA) Astex_1436 8ada720582a85548f7829bf69a6b2227 387 SUPERFAMILY SSF101801 299 374 4.45E-13 T 13-10-2018 IPR036429 SpoA-like superfamily Astex_1436 8ada720582a85548f7829bf69a6b2227 387 Gene3D G3DSA:3.40.1550.10 95 282 1.0E-51 T 13-10-2018 IPR028976 CheC-like superfamily Astex_1436 8ada720582a85548f7829bf69a6b2227 387 SUPERFAMILY SSF103039 96 281 1.46E-12 T 13-10-2018 IPR028976 CheC-like superfamily Astex_1436 8ada720582a85548f7829bf69a6b2227 387 Pfam PF02154 Flagellar motor switch protein FliM 89 281 6.7E-71 T 13-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 Astex_1436 8ada720582a85548f7829bf69a6b2227 387 TIGRFAM TIGR01397 fliM_switch: flagellar motor switch protein FliM 61 372 4.1E-102 T 13-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 Astex_1436 8ada720582a85548f7829bf69a6b2227 387 Gene3D G3DSA:2.30.330.10 296 383 5.2E-7 T 13-10-2018 IPR036429 SpoA-like superfamily Astex_2451 49f895c3c6d55c55ab281c04dd7e536f 683 SUPERFAMILY SSF109709 115 220 1.12E-18 T 13-10-2018 Astex_2451 49f895c3c6d55c55ab281c04dd7e536f 683 Gene3D G3DSA:3.90.1530.30 34 109 8.3E-6 T 13-10-2018 Astex_2451 49f895c3c6d55c55ab281c04dd7e536f 683 Pfam PF02195 ParB-like nuclease domain 21 121 1.2E-9 T 13-10-2018 IPR003115 ParB/Sulfiredoxin Astex_2451 49f895c3c6d55c55ab281c04dd7e536f 683 Gene3D G3DSA:1.10.10.2830 110 212 6.7E-15 T 13-10-2018 Astex_2451 49f895c3c6d55c55ab281c04dd7e536f 683 SUPERFAMILY SSF110849 21 124 2.62E-9 T 13-10-2018 IPR036086 ParB/Sulfiredoxin superfamily Astex_2451 49f895c3c6d55c55ab281c04dd7e536f 683 SMART SM00470 20 122 1.8E-10 T 13-10-2018 IPR003115 ParB/Sulfiredoxin Astex_2781 420b3892f3a007c49408edb164fa0681 92 TIGRFAM TIGR00165 S18: ribosomal protein bS18 23 91 2.3E-31 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_2781 420b3892f3a007c49408edb164fa0681 92 ProSitePatterns PS00057 Ribosomal protein S18 signature. 40 63 - T 13-10-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_2781 420b3892f3a007c49408edb164fa0681 92 Pfam PF01084 Ribosomal protein S18 38 87 2.0E-25 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_2781 420b3892f3a007c49408edb164fa0681 92 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 21 92 21.857 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_2781 420b3892f3a007c49408edb164fa0681 92 Gene3D G3DSA:4.10.640.10 14 92 9.0E-29 T 13-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_2781 420b3892f3a007c49408edb164fa0681 92 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 40 92 2.0E-22 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_2781 420b3892f3a007c49408edb164fa0681 92 PRINTS PR00974 Ribosomal protein S18 family signature 47 57 2.4E-18 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_2781 420b3892f3a007c49408edb164fa0681 92 PRINTS PR00974 Ribosomal protein S18 family signature 65 79 2.4E-18 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_2781 420b3892f3a007c49408edb164fa0681 92 PRINTS PR00974 Ribosomal protein S18 family signature 57 64 2.4E-18 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_2781 420b3892f3a007c49408edb164fa0681 92 PRINTS PR00974 Ribosomal protein S18 family signature 79 89 2.4E-18 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_2781 420b3892f3a007c49408edb164fa0681 92 SUPERFAMILY SSF46911 19 92 1.44E-28 T 13-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0798 ea5a4d2467ad353e8c1f0e06b2ef2030 208 Gene3D G3DSA:3.40.30.10 2 203 5.9E-85 T 13-10-2018 Astex_0798 ea5a4d2467ad353e8c1f0e06b2ef2030 208 SUPERFAMILY SSF47616 73 202 1.2E-39 T 13-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily Astex_0798 ea5a4d2467ad353e8c1f0e06b2ef2030 208 Pfam PF00043 Glutathione S-transferase, C-terminal domain 105 195 1.4E-15 T 13-10-2018 IPR004046 Glutathione S-transferase, C-terminal Astex_0798 ea5a4d2467ad353e8c1f0e06b2ef2030 208 SUPERFAMILY SSF52833 2 80 2.16E-22 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Astex_0798 ea5a4d2467ad353e8c1f0e06b2ef2030 208 Gene3D G3DSA:1.20.1050.10 83 194 5.9E-85 T 13-10-2018 Astex_0798 ea5a4d2467ad353e8c1f0e06b2ef2030 208 Pfam PF02798 Glutathione S-transferase, N-terminal domain 2 76 2.8E-15 T 13-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 Astex_3251 193362e8aa72031b81b4fb0e493b84c4 280 Gene3D G3DSA:3.60.110.10 7 278 5.8E-79 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily Astex_3251 193362e8aa72031b81b4fb0e493b84c4 280 Pfam PF00795 Carbon-nitrogen hydrolase 8 265 1.9E-42 T 13-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 Astex_3251 193362e8aa72031b81b4fb0e493b84c4 280 SUPERFAMILY SSF56317 6 273 2.75E-67 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily Astex_2895 799a1cd15f926d9bebef333c9389ef84 551 SUPERFAMILY SSF52317 296 547 1.56E-75 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Astex_2895 799a1cd15f926d9bebef333c9389ef84 551 Gene3D G3DSA:3.40.50.880 295 551 2.2E-97 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Astex_2895 799a1cd15f926d9bebef333c9389ef84 551 Gene3D G3DSA:3.40.50.300 2 292 2.7E-120 T 13-10-2018 Astex_2895 799a1cd15f926d9bebef333c9389ef84 551 SUPERFAMILY SSF52540 8 273 2.74E-117 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2895 799a1cd15f926d9bebef333c9389ef84 551 Pfam PF06418 CTP synthase N-terminus 10 270 4.8E-119 T 13-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 Astex_2895 799a1cd15f926d9bebef333c9389ef84 551 Hamap MF_01227 CTP synthase [pyrG]. 9 548 49.136 T 13-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 Astex_2895 799a1cd15f926d9bebef333c9389ef84 551 Pfam PF00117 Glutamine amidotransferase class-I 307 542 5.7E-54 T 13-10-2018 IPR017926 Glutamine amidotransferase Astex_2895 799a1cd15f926d9bebef333c9389ef84 551 TIGRFAM TIGR00337 PyrG: CTP synthase 8 543 2.6E-224 T 13-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 Astex_1674 c40545a8545f850377d5dec960d21b57 294 Pfam PF08478 POTRA domain, FtsQ-type 94 161 1.7E-16 T 13-10-2018 IPR013685 POTRA domain, FtsQ-type Astex_1674 c40545a8545f850377d5dec960d21b57 294 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 63 286 19.374 T 13-10-2018 IPR026579 Cell division protein FtsQ GO:0090529 Astex_1674 c40545a8545f850377d5dec960d21b57 294 Gene3D G3DSA:3.10.20.310 93 160 2.1E-11 T 13-10-2018 Astex_1674 c40545a8545f850377d5dec960d21b57 294 Pfam PF03799 Cell division protein FtsQ 165 277 7.0E-15 T 13-10-2018 IPR005548 Cell division protein FtsQ/DivIB Astex_3454 fe2b8828a10b92ab8f6415ff321f2dfc 318 Gene3D G3DSA:3.90.226.10 1 315 1.6E-109 T 13-10-2018 Astex_3454 fe2b8828a10b92ab8f6415ff321f2dfc 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 87 98 3.9E-41 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Astex_3454 fe2b8828a10b92ab8f6415ff321f2dfc 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 196 205 3.9E-41 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Astex_3454 fe2b8828a10b92ab8f6415ff321f2dfc 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 152 165 3.9E-41 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Astex_3454 fe2b8828a10b92ab8f6415ff321f2dfc 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 168 181 3.9E-41 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Astex_3454 fe2b8828a10b92ab8f6415ff321f2dfc 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 112 130 3.9E-41 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Astex_3454 fe2b8828a10b92ab8f6415ff321f2dfc 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 133 149 3.9E-41 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Astex_3454 fe2b8828a10b92ab8f6415ff321f2dfc 318 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 4 147 5.5E-59 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Astex_3454 fe2b8828a10b92ab8f6415ff321f2dfc 318 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 4 315 47.869 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Astex_3454 fe2b8828a10b92ab8f6415ff321f2dfc 318 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 2 315 2.7E-123 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 Astex_3454 fe2b8828a10b92ab8f6415ff321f2dfc 318 SUPERFAMILY SSF52096 4 314 1.91E-90 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Astex_2096 a133c8e34b5380e134191d3d5a5403cc 386 SUPERFAMILY SSF53383 12 384 1.97E-92 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Astex_2096 a133c8e34b5380e134191d3d5a5403cc 386 PIRSF PIRSF000390 5 386 1.4E-94 T 13-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase Astex_2096 a133c8e34b5380e134191d3d5a5403cc 386 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 17 381 1.4E-97 T 13-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase Astex_2096 a133c8e34b5380e134191d3d5a5403cc 386 Gene3D G3DSA:3.40.640.10 1 265 1.7E-76 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Astex_2096 a133c8e34b5380e134191d3d5a5403cc 386 Gene3D G3DSA:3.90.1150.10 267 386 4.6E-31 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Astex_1797 dc2b60144de89566ae7ebabb1a9a4f81 443 Pfam PF00202 Aminotransferase class-III 33 439 2.6E-97 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Astex_1797 dc2b60144de89566ae7ebabb1a9a4f81 443 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 253 290 - T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Astex_1797 dc2b60144de89566ae7ebabb1a9a4f81 443 Gene3D G3DSA:3.90.1150.10 32 434 2.0E-148 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Astex_1797 dc2b60144de89566ae7ebabb1a9a4f81 443 PIRSF PIRSF000521 26 151 1.2E-5 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Astex_1797 dc2b60144de89566ae7ebabb1a9a4f81 443 PIRSF PIRSF000521 139 442 1.5E-21 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Astex_1797 dc2b60144de89566ae7ebabb1a9a4f81 443 Gene3D G3DSA:3.40.640.10 66 345 2.0E-148 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Astex_1797 dc2b60144de89566ae7ebabb1a9a4f81 443 SUPERFAMILY SSF53383 15 440 6.68E-123 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Astex_0244 e29e2e761da0fbbbf704ed220e8ec7ae 675 Pfam PF13844 Glycosyl transferase family 41 415 608 2.4E-47 T 13-10-2018 IPR029489 O-GlcNAc transferase, C-terminal KEGG: 00514+2.4.1.255|MetaCyc: PWY-7437|Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 Astex_0244 e29e2e761da0fbbbf704ed220e8ec7ae 675 Pfam PF13844 Glycosyl transferase family 41 254 395 1.2E-39 T 13-10-2018 IPR029489 O-GlcNAc transferase, C-terminal KEGG: 00514+2.4.1.255|MetaCyc: PWY-7437|Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 Astex_0244 e29e2e761da0fbbbf704ed220e8ec7ae 675 SMART SM00028 136 169 42.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Astex_0244 e29e2e761da0fbbbf704ed220e8ec7ae 675 SMART SM00028 60 93 0.022 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Astex_0244 e29e2e761da0fbbbf704ed220e8ec7ae 675 SUPERFAMILY SSF48452 26 171 1.67E-12 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_0244 e29e2e761da0fbbbf704ed220e8ec7ae 675 Gene3D G3DSA:1.25.40.10 10 185 5.7E-16 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_0244 e29e2e761da0fbbbf704ed220e8ec7ae 675 Gene3D G3DSA:3.40.50.11380 242 595 1.2E-135 T 13-10-2018 Astex_0244 e29e2e761da0fbbbf704ed220e8ec7ae 675 SUPERFAMILY SSF53756 411 580 1.73E-8 T 13-10-2018 Astex_0244 e29e2e761da0fbbbf704ed220e8ec7ae 675 Pfam PF13181 Tetratricopeptide repeat 62 92 0.054 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Astex_0244 e29e2e761da0fbbbf704ed220e8ec7ae 675 Gene3D G3DSA:3.40.50.2000 411 590 1.2E-135 T 13-10-2018 Astex_3354 cdd429c2bdd26dcbfb84e377ee8934bf 863 Gene3D G3DSA:3.30.379.10 225 344 6.0E-12 T 13-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 Astex_3354 cdd429c2bdd26dcbfb84e377ee8934bf 863 Gene3D G3DSA:2.60.40.10 801 862 2.0E-16 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_3354 cdd429c2bdd26dcbfb84e377ee8934bf 863 SMART SM01081 55 214 5.2E-27 T 13-10-2018 IPR004866 Chitobiase/beta-hexosaminidases, N-terminal domain KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883 Astex_3354 cdd429c2bdd26dcbfb84e377ee8934bf 863 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 232 343 4.6E-9 T 13-10-2018 IPR015882 Beta-hexosaminidase, bacterial type, N-terminal Astex_3354 cdd429c2bdd26dcbfb84e377ee8934bf 863 SUPERFAMILY SSF55545 226 345 6.28E-15 T 13-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 Astex_3354 cdd429c2bdd26dcbfb84e377ee8934bf 863 PRINTS PR00738 Glycosyl hydrolase family 20 signature 711 727 1.2E-42 T 13-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 Astex_3354 cdd429c2bdd26dcbfb84e377ee8934bf 863 PRINTS PR00738 Glycosyl hydrolase family 20 signature 539 552 1.2E-42 T 13-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 Astex_3354 cdd429c2bdd26dcbfb84e377ee8934bf 863 PRINTS PR00738 Glycosyl hydrolase family 20 signature 369 390 1.2E-42 T 13-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 Astex_3354 cdd429c2bdd26dcbfb84e377ee8934bf 863 PRINTS PR00738 Glycosyl hydrolase family 20 signature 729 746 1.2E-42 T 13-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 Astex_3354 cdd429c2bdd26dcbfb84e377ee8934bf 863 PRINTS PR00738 Glycosyl hydrolase family 20 signature 307 327 1.2E-42 T 13-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 Astex_3354 cdd429c2bdd26dcbfb84e377ee8934bf 863 PRINTS PR00738 Glycosyl hydrolase family 20 signature 446 463 1.2E-42 T 13-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 Astex_3354 cdd429c2bdd26dcbfb84e377ee8934bf 863 PRINTS PR00738 Glycosyl hydrolase family 20 signature 512 530 1.2E-42 T 13-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 Astex_3354 cdd429c2bdd26dcbfb84e377ee8934bf 863 PRINTS PR00738 Glycosyl hydrolase family 20 signature 340 357 1.2E-42 T 13-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 Astex_3354 cdd429c2bdd26dcbfb84e377ee8934bf 863 Gene3D G3DSA:2.60.40.290 46 175 6.8E-16 T 13-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 Astex_3354 cdd429c2bdd26dcbfb84e377ee8934bf 863 Gene3D G3DSA:3.20.20.80 345 799 4.9E-142 T 13-10-2018 Astex_3354 cdd429c2bdd26dcbfb84e377ee8934bf 863 Pfam PF03174 Chitobiase/beta-hexosaminidase C-terminal domain 787 859 1.5E-23 T 13-10-2018 IPR004867 Chitobiase C-terminal domain KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883 Astex_3354 cdd429c2bdd26dcbfb84e377ee8934bf 863 SUPERFAMILY SSF49384 47 217 6.49E-27 T 13-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 Astex_3354 cdd429c2bdd26dcbfb84e377ee8934bf 863 Pfam PF03173 Putative carbohydrate binding domain 69 213 1.4E-18 T 13-10-2018 IPR004866 Chitobiase/beta-hexosaminidases, N-terminal domain KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883 Astex_3354 cdd429c2bdd26dcbfb84e377ee8934bf 863 SUPERFAMILY SSF51445 347 756 1.22E-124 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_3354 cdd429c2bdd26dcbfb84e377ee8934bf 863 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 347 747 1.9E-93 T 13-10-2018 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883 Astex_3354 cdd429c2bdd26dcbfb84e377ee8934bf 863 SUPERFAMILY SSF81296 767 862 4.48E-19 T 13-10-2018 IPR014756 Immunoglobulin E-set Astex_0416 87d3aa1a5f28430b8fc1ebb0609c0396 349 SMART SM00858 291 349 4.2E-9 T 13-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 Astex_0416 87d3aa1a5f28430b8fc1ebb0609c0396 349 TIGRFAM TIGR03586 PseI: pseudaminic acid synthase 18 343 1.5E-150 T 13-10-2018 IPR020030 Pseudaminic acid biosynthesis, PseI KEGG: 00520+2.5.1.97|MetaCyc: PWY-6143 Astex_0416 87d3aa1a5f28430b8fc1ebb0609c0396 349 Pfam PF03102 NeuB family 38 276 3.5E-88 T 13-10-2018 IPR013132 N-acetylneuraminic acid synthase, N-terminal GO:0016051 Reactome: R-HSA-4085001 Astex_0416 87d3aa1a5f28430b8fc1ebb0609c0396 349 Gene3D G3DSA:3.90.1210.10 283 348 7.6E-18 T 13-10-2018 Astex_0416 87d3aa1a5f28430b8fc1ebb0609c0396 349 SUPERFAMILY SSF51569 4 301 2.69E-88 T 13-10-2018 Astex_0416 87d3aa1a5f28430b8fc1ebb0609c0396 349 Pfam PF08666 SAF domain 292 348 3.1E-9 T 13-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 Astex_0416 87d3aa1a5f28430b8fc1ebb0609c0396 349 Gene3D G3DSA:3.20.20.70 4 276 1.8E-92 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_0416 87d3aa1a5f28430b8fc1ebb0609c0396 349 SUPERFAMILY SSF51269 287 348 3.14E-17 T 13-10-2018 IPR036732 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily Reactome: R-HSA-4085001 Astex_3287 651f01ca450ed0b9e6afd2f5dd0c6b12 194 Gene3D G3DSA:3.90.550.10 2 192 2.2E-34 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_3287 651f01ca450ed0b9e6afd2f5dd0c6b12 194 SUPERFAMILY SSF53448 5 185 8.56E-22 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_3287 651f01ca450ed0b9e6afd2f5dd0c6b12 194 Pfam PF12804 MobA-like NTP transferase domain 9 160 1.2E-25 T 13-10-2018 IPR025877 MobA-like NTP transferase Astex_0454 6c554055eb0147351e92f88bfebc15d6 470 PIRSF PIRSF019251 3 470 1.0E-164 T 13-10-2018 IPR026281 HTH-type transcriptional regulator RamB GO:0006355 Astex_0454 6c554055eb0147351e92f88bfebc15d6 470 SUPERFAMILY SSF47413 8 73 6.44E-14 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Astex_0454 6c554055eb0147351e92f88bfebc15d6 470 Pfam PF06114 IrrE N-terminal-like domain 189 311 1.2E-16 T 13-10-2018 IPR010359 IrrE N-terminal-like domain Astex_0454 6c554055eb0147351e92f88bfebc15d6 470 Pfam PF13560 Helix-turn-helix domain 10 64 1.1E-11 T 13-10-2018 Astex_0454 6c554055eb0147351e92f88bfebc15d6 470 Gene3D G3DSA:1.10.260.40 9 86 1.0E-13 T 13-10-2018 Astex_0454 6c554055eb0147351e92f88bfebc15d6 470 Pfam PF09856 Predicted transcriptional regulator (DUF2083) 312 468 1.9E-61 T 13-10-2018 IPR018653 Domain of unknown function DUF2083,transcriptional regulator Astex_0454 6c554055eb0147351e92f88bfebc15d6 470 SMART SM00530 13 68 3.9E-13 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Astex_1461 73318dd1cc0fb8d2016997b5bc683b59 240 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 191 1.9E-9 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Astex_1461 73318dd1cc0fb8d2016997b5bc683b59 240 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 207 219 1.9E-9 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Astex_1461 73318dd1cc0fb8d2016997b5bc683b59 240 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 191 207 1.9E-9 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Astex_1461 73318dd1cc0fb8d2016997b5bc683b59 240 Pfam PF00196 Bacterial regulatory proteins, luxR family 177 230 6.5E-18 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Astex_1461 73318dd1cc0fb8d2016997b5bc683b59 240 ProSitePatterns PS00622 LuxR-type HTH domain signature. 191 218 - T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Astex_1461 73318dd1cc0fb8d2016997b5bc683b59 240 Gene3D G3DSA:3.40.50.2300 34 159 1.9E-22 T 13-10-2018 Astex_1461 73318dd1cc0fb8d2016997b5bc683b59 240 SMART SM00421 174 231 1.2E-20 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Astex_1461 73318dd1cc0fb8d2016997b5bc683b59 240 Gene3D G3DSA:1.10.10.10 174 238 1.2E-20 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1461 73318dd1cc0fb8d2016997b5bc683b59 240 SUPERFAMILY SSF52172 35 157 3.7E-22 T 13-10-2018 IPR011006 CheY-like superfamily Astex_1461 73318dd1cc0fb8d2016997b5bc683b59 240 SMART SM00448 35 149 6.8E-17 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1461 73318dd1cc0fb8d2016997b5bc683b59 240 SUPERFAMILY SSF46894 166 236 3.74E-19 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Astex_1461 73318dd1cc0fb8d2016997b5bc683b59 240 Pfam PF00072 Response regulator receiver domain 37 149 5.1E-18 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_2212 9825d7455aadbabef2dc59c5b9baadb4 372 Gene3D G3DSA:3.40.50.2000 194 336 2.1E-27 T 13-10-2018 Astex_2212 9825d7455aadbabef2dc59c5b9baadb4 372 Pfam PF00534 Glycosyl transferases group 1 194 326 3.8E-23 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 Astex_2212 9825d7455aadbabef2dc59c5b9baadb4 372 Pfam PF13439 Glycosyltransferase Family 4 41 187 2.4E-12 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 Astex_2212 9825d7455aadbabef2dc59c5b9baadb4 372 Gene3D G3DSA:3.40.50.2000 1 193 1.4E-8 T 13-10-2018 Astex_2212 9825d7455aadbabef2dc59c5b9baadb4 372 SUPERFAMILY SSF53756 1 351 4.32E-56 T 13-10-2018 Astex_0386 108b0e9cdb5e85a7b5e7c2b6416da533 391 Pfam PF04893 Yip1 domain 19 182 3.0E-19 T 13-10-2018 IPR006977 Yip1 domain GO:0016020 Astex_2296 02fb4aa600fea9bc93f5bc3144fffdf6 200 PIRSF PIRSF035805 1 184 8.1E-49 T 13-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 Astex_2296 02fb4aa600fea9bc93f5bc3144fffdf6 200 Gene3D G3DSA:3.30.60.20 140 182 2.3E-8 T 13-10-2018 Astex_2296 02fb4aa600fea9bc93f5bc3144fffdf6 200 Pfam PF00265 Thymidine kinase 3 179 5.6E-41 T 13-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 Astex_2296 02fb4aa600fea9bc93f5bc3144fffdf6 200 SUPERFAMILY SSF57716 140 181 2.28E-8 T 13-10-2018 Astex_2296 02fb4aa600fea9bc93f5bc3144fffdf6 200 Gene3D G3DSA:3.40.50.300 1 139 4.5E-39 T 13-10-2018 Astex_2296 02fb4aa600fea9bc93f5bc3144fffdf6 200 SUPERFAMILY SSF52540 2 140 2.05E-32 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2296 02fb4aa600fea9bc93f5bc3144fffdf6 200 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 166 179 - T 13-10-2018 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 Astex_3510 59cfdc38c4edf574d78a80f98192160a 117 PIRSF PIRSF033199 1 116 9.2E-54 T 13-10-2018 IPR014580 Uncharacterised conserved protein UCP033199 Astex_3510 59cfdc38c4edf574d78a80f98192160a 117 Gene3D G3DSA:1.10.8.290 1 117 1.4E-52 T 13-10-2018 IPR023204 SP1917 domain superfamily Astex_3510 59cfdc38c4edf574d78a80f98192160a 117 Pfam PF09966 Uncharacterized protein conserved in bacteria (DUF2200) 5 115 7.0E-52 T 13-10-2018 IPR014580 Uncharacterised conserved protein UCP033199 Astex_3254 5124e6d3e7e0fc3865618bd41d5e4cf3 293 Pfam PF08241 Methyltransferase domain 88 138 7.5E-9 T 13-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 Astex_3254 5124e6d3e7e0fc3865618bd41d5e4cf3 293 Gene3D G3DSA:3.40.50.150 35 259 1.8E-14 T 13-10-2018 Astex_3254 5124e6d3e7e0fc3865618bd41d5e4cf3 293 SUPERFAMILY SSF53335 34 216 2.76E-19 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Astex_2552 5613024a6843d2b98eb7f1e8648c4e97 514 Gene3D G3DSA:3.90.1300.10 16 514 9.4E-175 T 13-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Astex_2552 5613024a6843d2b98eb7f1e8648c4e97 514 Pfam PF01425 Amidase 49 496 2.9E-93 T 13-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Astex_2552 5613024a6843d2b98eb7f1e8648c4e97 514 SUPERFAMILY SSF75304 27 511 9.16E-117 T 13-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Astex_3503 65dce2461b1b2afad461b66263662c40 165 Gene3D G3DSA:3.40.50.12740 6 151 2.3E-30 T 13-10-2018 Astex_3503 65dce2461b1b2afad461b66263662c40 165 SUPERFAMILY SSF52172 7 131 1.37E-32 T 13-10-2018 IPR011006 CheY-like superfamily Astex_3503 65dce2461b1b2afad461b66263662c40 165 SMART SM00448 7 123 4.9E-31 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_3503 65dce2461b1b2afad461b66263662c40 165 Pfam PF00072 Response regulator receiver domain 9 123 5.8E-25 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_3335 4e96d7141f5619b4c060b809430c421c 1042 SUPERFAMILY SSF56935 38 1040 1.47E-65 T 13-10-2018 Astex_3335 4e96d7141f5619b4c060b809430c421c 1042 Pfam PF07715 TonB-dependent Receptor Plug Domain 67 178 3.3E-12 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_3335 4e96d7141f5619b4c060b809430c421c 1042 Pfam PF00593 TonB dependent receptor 487 1041 1.7E-25 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_3335 4e96d7141f5619b4c060b809430c421c 1042 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 48 1040 4.4E-162 T 13-10-2018 IPR010104 Bacterial TonB-dependent receptor Astex_3335 4e96d7141f5619b4c060b809430c421c 1042 Gene3D G3DSA:2.170.130.10 40 183 1.4E-15 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_3335 4e96d7141f5619b4c060b809430c421c 1042 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 55 - T 13-10-2018 IPR010916 TonB box, conserved site Astex_1585 f68741a7087875288330abb7c896d90e 188 Pfam PF08006 Protein of unknown function (DUF1700) 1 173 8.0E-28 T 13-10-2018 IPR012963 Protein of unknown function DUF1700 Astex_2767 419fdc301ca7b397a946b696a6345b10 132 Gene3D G3DSA:2.60.300.12 18 124 5.5E-32 T 13-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 Astex_2767 419fdc301ca7b397a946b696a6345b10 132 SUPERFAMILY SSF89360 14 110 1.06E-27 T 13-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 Astex_2767 419fdc301ca7b397a946b696a6345b10 132 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 19 122 1.0E-33 T 13-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 Astex_2767 419fdc301ca7b397a946b696a6345b10 132 Pfam PF01521 Iron-sulphur cluster biosynthesis 19 120 3.2E-18 T 13-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 Astex_2094 6ef5afc096ad1745b4949255fffd3b15 427 SUPERFAMILY SSF111352 25 407 4.18E-122 T 13-10-2018 Astex_2094 6ef5afc096ad1745b4949255fffd3b15 427 ProSitePatterns PS01219 Ammonium transporters signature. 188 213 - T 13-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 Astex_2094 6ef5afc096ad1745b4949255fffd3b15 427 Pfam PF00909 Ammonium Transporter Family 32 425 4.8E-122 T 13-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 Astex_2094 6ef5afc096ad1745b4949255fffd3b15 427 Gene3D G3DSA:1.10.3430.10 3 427 5.2E-140 T 13-10-2018 IPR029020 Ammonium/urea transporter Astex_2094 6ef5afc096ad1745b4949255fffd3b15 427 TIGRFAM TIGR00836 amt: ammonium transporter 30 424 1.6E-136 T 13-10-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 Astex_1945 cba8a6c3e9e7289b6f9d8ed72e316721 529 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 48 449 2.4E-101 T 13-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 Astex_1945 cba8a6c3e9e7289b6f9d8ed72e316721 529 Pfam PF00474 Sodium:solute symporter family 48 447 9.1E-62 T 13-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 Astex_1945 cba8a6c3e9e7289b6f9d8ed72e316721 529 Gene3D G3DSA:1.20.1730.10 36 529 7.9E-158 T 13-10-2018 IPR038377 Sodium/glucose symporter superfamily Astex_0282 5c1122502c8ef95c534ae00f66fa5564 308 Gene3D G3DSA:3.40.50.1820 58 307 1.1E-52 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_0282 5c1122502c8ef95c534ae00f66fa5564 308 SUPERFAMILY SSF53474 66 301 5.26E-37 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_0282 5c1122502c8ef95c534ae00f66fa5564 308 Pfam PF07859 alpha/beta hydrolase fold 144 214 2.2E-9 T 13-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 Astex_2525 44266db325a16c402bfe3174242953a5 408 Gene3D G3DSA:3.90.1150.10 13 384 4.1E-128 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Astex_2525 44266db325a16c402bfe3174242953a5 408 PIRSF PIRSF000524 7 407 2.9E-104 T 13-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 Astex_2525 44266db325a16c402bfe3174242953a5 408 Gene3D G3DSA:3.40.640.10 24 286 4.1E-128 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Astex_2525 44266db325a16c402bfe3174242953a5 408 SUPERFAMILY SSF53383 9 387 3.55E-86 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Astex_2525 44266db325a16c402bfe3174242953a5 408 Pfam PF00266 Aminotransferase class-V 26 351 4.6E-21 T 13-10-2018 IPR000192 Aminotransferase class V domain Astex_2520 fbbda2acd6cef0a41f0d2321e30e0676 299 Pfam PF03466 LysR substrate binding domain 93 291 5.2E-43 T 13-10-2018 IPR005119 LysR, substrate-binding Astex_2520 fbbda2acd6cef0a41f0d2321e30e0676 299 Gene3D G3DSA:3.40.190.10 166 265 9.3E-65 T 13-10-2018 Astex_2520 fbbda2acd6cef0a41f0d2321e30e0676 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 1.4E-16 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_2520 fbbda2acd6cef0a41f0d2321e30e0676 299 Gene3D G3DSA:3.40.190.10 95 290 9.3E-65 T 13-10-2018 Astex_2520 fbbda2acd6cef0a41f0d2321e30e0676 299 Gene3D G3DSA:1.10.10.10 5 92 7.2E-25 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_2520 fbbda2acd6cef0a41f0d2321e30e0676 299 SUPERFAMILY SSF53850 93 297 1.99E-44 T 13-10-2018 Astex_2520 fbbda2acd6cef0a41f0d2321e30e0676 299 SUPERFAMILY SSF46785 5 115 8.32E-21 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_2410 bfab253a09a37bff9cf794912934a7d9 345 SUPERFAMILY SSF51556 8 337 8.38E-89 T 13-10-2018 IPR032466 Metal-dependent hydrolase Astex_2410 bfab253a09a37bff9cf794912934a7d9 345 Gene3D G3DSA:3.20.20.140 7 344 1.0E-86 T 13-10-2018 Astex_2410 bfab253a09a37bff9cf794912934a7d9 345 Pfam PF04909 Amidohydrolase 9 334 1.4E-56 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 Astex_1596 6c2fb8823f20424b05e79222ff71e88b 287 Gene3D G3DSA:3.40.50.150 141 236 4.6E-6 T 13-10-2018 Astex_1596 6c2fb8823f20424b05e79222ff71e88b 287 Gene3D G3DSA:3.40.50.150 44 110 2.6E-5 T 13-10-2018 Astex_1596 6c2fb8823f20424b05e79222ff71e88b 287 PIRSF PIRSF031679 2 287 3.1E-76 T 13-10-2018 IPR016980 S-adenosyl-L-methionine dependent methyltransferase, Alr7345, predicted Astex_1596 6c2fb8823f20424b05e79222ff71e88b 287 SUPERFAMILY SSF53335 62 246 2.55E-10 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Astex_2791 338aa02f65d35d2c974b88a90f6708c5 352 Gene3D G3DSA:3.30.160.60 306 340 1.0E-11 T 13-10-2018 Astex_2791 338aa02f65d35d2c974b88a90f6708c5 352 Pfam PF02618 YceG-like family 58 331 5.2E-80 T 13-10-2018 IPR003770 Endolytic murein transglycosylase Astex_2791 338aa02f65d35d2c974b88a90f6708c5 352 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 28 334 32.754 T 13-10-2018 IPR003770 Endolytic murein transglycosylase Astex_2791 338aa02f65d35d2c974b88a90f6708c5 352 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 157 331 3.5E-56 T 13-10-2018 IPR003770 Endolytic murein transglycosylase Astex_2791 338aa02f65d35d2c974b88a90f6708c5 352 Gene3D G3DSA:1.10.8.1150 53 127 5.5E-13 T 13-10-2018 Astex_1319 5527627fb84de0a621b31dc75907920d 417 SUPERFAMILY SSF51126 30 367 1.26E-35 T 13-10-2018 IPR011050 Pectin lyase fold/virulence factor Astex_1319 5527627fb84de0a621b31dc75907920d 417 Gene3D G3DSA:2.160.20.10 16 285 1.2E-42 T 13-10-2018 IPR012334 Pectin lyase fold Astex_1863 1572d53209a71bc2d6ec4edf52a21fc9 354 SUPERFAMILY SSF82282 9 354 2.35E-99 T 13-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 Astex_1863 1572d53209a71bc2d6ec4edf52a21fc9 354 PIRSF PIRSF037505 57 150 0.011 T 13-10-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 Astex_1863 1572d53209a71bc2d6ec4edf52a21fc9 354 PIRSF PIRSF037505 234 346 0.033 T 13-10-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 Astex_1863 1572d53209a71bc2d6ec4edf52a21fc9 354 Gene3D G3DSA:3.20.20.330 3 342 2.5E-123 T 13-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 Astex_1863 1572d53209a71bc2d6ec4edf52a21fc9 354 Pfam PF02574 Homocysteine S-methyltransferase 19 328 6.6E-78 T 13-10-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 Astex_1280 41d6443636eed58d150a5f2de4fce716 373 SMART SM00729 85 313 1.1E-6 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Astex_1280 41d6443636eed58d150a5f2de4fce716 373 SUPERFAMILY SSF102114 86 275 7.06E-11 T 13-10-2018 Astex_1280 41d6443636eed58d150a5f2de4fce716 373 Pfam PF04055 Radical SAM superfamily 89 267 2.8E-13 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Astex_3778 9d0a6559d8f5ddb32c4c03afce361631 422 Pfam PF03428 Replication protein C N-terminal domain 8 169 9.0E-10 T 13-10-2018 IPR005090 Replication protein C Astex_2472 978e597f4e4657bc3f43412f21fa0e03 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 2.0E-26 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2472 978e597f4e4657bc3f43412f21fa0e03 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 2.0E-26 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2472 978e597f4e4657bc3f43412f21fa0e03 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 2.0E-26 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2472 978e597f4e4657bc3f43412f21fa0e03 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 2.0E-26 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2472 978e597f4e4657bc3f43412f21fa0e03 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 2.0E-26 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2472 978e597f4e4657bc3f43412f21fa0e03 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 2.0E-26 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2472 978e597f4e4657bc3f43412f21fa0e03 273 Gene3D G3DSA:3.40.50.720 2 273 5.0E-72 T 13-10-2018 Astex_2472 978e597f4e4657bc3f43412f21fa0e03 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 165 3.0E-11 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2472 978e597f4e4657bc3f43412f21fa0e03 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 134 3.0E-11 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2472 978e597f4e4657bc3f43412f21fa0e03 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 3.0E-11 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2472 978e597f4e4657bc3f43412f21fa0e03 273 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 133 161 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Astex_2472 978e597f4e4657bc3f43412f21fa0e03 273 SUPERFAMILY SSF51735 3 244 5.11E-60 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_2472 978e597f4e4657bc3f43412f21fa0e03 273 Pfam PF00106 short chain dehydrogenase 4 185 1.4E-48 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_3425 d7fa61c8b4a54dfff240080270fa6179 214 Pfam PF01144 Coenzyme A transferase 6 202 2.7E-41 T 13-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 Astex_3425 d7fa61c8b4a54dfff240080270fa6179 214 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 3 210 7.1E-97 T 13-10-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 Astex_3425 d7fa61c8b4a54dfff240080270fa6179 214 Gene3D G3DSA:3.40.1080.10 2 214 3.5E-99 T 13-10-2018 Astex_3425 d7fa61c8b4a54dfff240080270fa6179 214 SUPERFAMILY SSF100950 3 212 2.13E-72 T 13-10-2018 IPR037171 NagB/RpiA transferase-like Astex_3425 d7fa61c8b4a54dfff240080270fa6179 214 SMART SM00882 6 204 1.7E-77 T 13-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 Astex_1523 d7fa61c8b4a54dfff240080270fa6179 214 Pfam PF01144 Coenzyme A transferase 6 202 2.7E-41 T 13-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 Astex_1523 d7fa61c8b4a54dfff240080270fa6179 214 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 3 210 7.1E-97 T 13-10-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 Astex_1523 d7fa61c8b4a54dfff240080270fa6179 214 Gene3D G3DSA:3.40.1080.10 2 214 3.5E-99 T 13-10-2018 Astex_1523 d7fa61c8b4a54dfff240080270fa6179 214 SUPERFAMILY SSF100950 3 212 2.13E-72 T 13-10-2018 IPR037171 NagB/RpiA transferase-like Astex_1523 d7fa61c8b4a54dfff240080270fa6179 214 SMART SM00882 6 204 1.7E-77 T 13-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 Astex_2307 63c31a333e21a0628fdaecf2a979b2ec 400 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 22 398 1.9E-123 T 13-10-2018 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 Astex_2307 63c31a333e21a0628fdaecf2a979b2ec 400 SUPERFAMILY SSF53686 6 310 1.57E-87 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme Astex_2307 63c31a333e21a0628fdaecf2a979b2ec 400 Gene3D G3DSA:3.40.50.1100 8 307 1.7E-106 T 13-10-2018 Astex_2307 63c31a333e21a0628fdaecf2a979b2ec 400 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 16 302 2.2E-69 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme Astex_2307 63c31a333e21a0628fdaecf2a979b2ec 400 Gene3D G3DSA:3.30.70.260 324 397 4.7E-5 T 13-10-2018 Astex_2307 63c31a333e21a0628fdaecf2a979b2ec 400 SUPERFAMILY SSF55021 328 395 1.71E-5 T 13-10-2018 Astex_2307 63c31a333e21a0628fdaecf2a979b2ec 400 Gene3D G3DSA:3.40.50.1100 51 147 1.7E-106 T 13-10-2018 Astex_1013 fc14ac09c74a101bc5d7b0f89dce55f7 340 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 27 54 1.4E-5 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_1013 fc14ac09c74a101bc5d7b0f89dce55f7 340 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 56 85 1.4E-5 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_1013 fc14ac09c74a101bc5d7b0f89dce55f7 340 Gene3D G3DSA:3.30.450.20 143 244 2.5E-7 T 13-10-2018 Astex_1013 fc14ac09c74a101bc5d7b0f89dce55f7 340 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 25 92 9.2E-13 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_1013 fc14ac09c74a101bc5d7b0f89dce55f7 340 SUPERFAMILY SSF58104 22 97 5.49E-16 T 13-10-2018 Astex_1013 fc14ac09c74a101bc5d7b0f89dce55f7 340 Gene3D G3DSA:1.10.287.950 2 127 1.3E-16 T 13-10-2018 Astex_1371 786c73b1be0f7afe25a4ef94a086a298 289 PIRSF PIRSF006493 1 289 6.3E-87 T 13-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type Astex_1371 786c73b1be0f7afe25a4ef94a086a298 289 TIGRFAM TIGR02772 Ku_bact: Ku protein 4 257 2.6E-86 T 13-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type Astex_1371 786c73b1be0f7afe25a4ef94a086a298 289 SUPERFAMILY SSF100939 4 256 6.67E-48 T 13-10-2018 IPR016194 SPOC-like, C-terminal domain superfamily Astex_1371 786c73b1be0f7afe25a4ef94a086a298 289 Gene3D G3DSA:2.40.290.10 5 181 3.5E-18 T 13-10-2018 IPR016194 SPOC-like, C-terminal domain superfamily Astex_1371 786c73b1be0f7afe25a4ef94a086a298 289 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 3 256 30.496 T 13-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type Astex_1371 786c73b1be0f7afe25a4ef94a086a298 289 SMART SM00559 54 182 3.0E-21 T 13-10-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 Astex_1371 786c73b1be0f7afe25a4ef94a086a298 289 Pfam PF02735 Ku70/Ku80 beta-barrel domain 14 193 7.2E-34 T 13-10-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 Astex_2077 d8ec78776ec9ea8b937fa879936107f3 965 Gene3D G3DSA:2.170.130.10 34 168 2.6E-39 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_2077 d8ec78776ec9ea8b937fa879936107f3 965 SUPERFAMILY SSF56935 40 965 1.88E-92 T 13-10-2018 Astex_2077 d8ec78776ec9ea8b937fa879936107f3 965 Pfam PF07715 TonB-dependent Receptor Plug Domain 54 164 2.2E-25 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_2077 d8ec78776ec9ea8b937fa879936107f3 965 Pfam PF00593 TonB dependent receptor 399 963 3.4E-44 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_2077 d8ec78776ec9ea8b937fa879936107f3 965 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 948 965 - T 13-10-2018 IPR010917 TonB-dependent receptor, conserved site Astex_1485 83d3f26f463fa86aedb9925ce7bc1568 348 SUPERFAMILY SSF55729 21 144 1.55E-9 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Astex_1485 83d3f26f463fa86aedb9925ce7bc1568 348 Gene3D G3DSA:3.40.630.30 7 151 2.6E-8 T 13-10-2018 Astex_2830 b043b6f5f1e2e49f86511c97d8484766 77 Pfam PF11003 Protein of unknown function (DUF2842) 14 70 1.8E-17 T 13-10-2018 IPR021265 Protein of unknown function DUF2842 Astex_0636 7b6fef4ca71fccea6bdfa08a1ae6cc5b 334 PIRSF PIRSF034367 2 334 2.4E-179 T 13-10-2018 IPR015004 Protein of unknown function DUF1852 Astex_0636 7b6fef4ca71fccea6bdfa08a1ae6cc5b 334 Pfam PF08908 Domain of unknown function (DUF1852) 11 331 2.9E-175 T 13-10-2018 IPR015004 Protein of unknown function DUF1852 Astex_0201 6b7cf63796931e30498b53e91e8e583f 409 SUPERFAMILY SSF53756 48 397 3.23E-24 T 13-10-2018 Astex_0201 6b7cf63796931e30498b53e91e8e583f 409 Pfam PF13692 Glycosyl transferases group 1 253 329 3.0E-8 T 13-10-2018 Astex_0201 6b7cf63796931e30498b53e91e8e583f 409 Gene3D G3DSA:3.40.50.2000 198 402 6.3E-24 T 13-10-2018 Astex_2363 cd5babb2b667a074586cee3786e13485 131 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 4 114 4.1E-38 T 13-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 Astex_2363 cd5babb2b667a074586cee3786e13485 131 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 3 130 22.488 T 13-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 Astex_2363 cd5babb2b667a074586cee3786e13485 131 Gene3D G3DSA:1.10.1200.120 3 131 1.9E-37 T 13-10-2018 IPR036019 Gated mechanosensitive channel Astex_2363 cd5babb2b667a074586cee3786e13485 131 SUPERFAMILY SSF81330 12 113 1.14E-33 T 13-10-2018 IPR036019 Gated mechanosensitive channel Astex_2363 cd5babb2b667a074586cee3786e13485 131 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 4 128 9.5E-41 T 13-10-2018 IPR037673 Large-conductance mechanosensitive channel/anditomin synthesis protein L Astex_2363 cd5babb2b667a074586cee3786e13485 131 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 84 92 1.5E-10 T 13-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 Astex_2363 cd5babb2b667a074586cee3786e13485 131 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 93 102 1.5E-10 T 13-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 Astex_2363 cd5babb2b667a074586cee3786e13485 131 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 6 20 1.5E-10 T 13-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 Astex_2363 cd5babb2b667a074586cee3786e13485 131 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 13 26 - T 13-10-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site Astex_2668 7ad1ef2e433394c883fd0c14300de5af 814 SUPERFAMILY SSF52540 401 750 3.11E-48 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2668 7ad1ef2e433394c883fd0c14300de5af 814 SMART SM00382 442 704 0.0036 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_2668 7ad1ef2e433394c883fd0c14300de5af 814 Pfam PF03135 CagE, TrbE, VirB family, component of type IV transporter system 181 390 2.2E-12 T 13-10-2018 IPR018145 CagE, TrbE, VirB component of type IV transporter system, central domain GO:0005524 Astex_3071 9ddb3898a63cd71db441a3afb5215a2a 737 Gene3D G3DSA:3.30.1330.10 50 199 3.0E-131 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Astex_3071 9ddb3898a63cd71db441a3afb5215a2a 737 SUPERFAMILY SSF55326 396 566 7.33E-54 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Astex_3071 9ddb3898a63cd71db441a3afb5215a2a 737 Pfam PF00586 AIR synthase related protein, N-terminal domain 443 559 4.8E-24 T 13-10-2018 IPR016188 PurM-like, N-terminal domain Astex_3071 9ddb3898a63cd71db441a3afb5215a2a 737 Pfam PF00586 AIR synthase related protein, N-terminal domain 94 194 1.0E-22 T 13-10-2018 IPR016188 PurM-like, N-terminal domain Astex_3071 9ddb3898a63cd71db441a3afb5215a2a 737 Gene3D G3DSA:3.30.1330.10 393 563 5.7E-55 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Astex_3071 9ddb3898a63cd71db441a3afb5215a2a 737 SUPERFAMILY SSF56042 205 426 6.88E-56 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Astex_3071 9ddb3898a63cd71db441a3afb5215a2a 737 Pfam PF02769 AIR synthase related protein, C-terminal domain 208 361 2.3E-34 T 13-10-2018 IPR010918 PurM-like, C-terminal domain Astex_3071 9ddb3898a63cd71db441a3afb5215a2a 737 Pfam PF02769 AIR synthase related protein, C-terminal domain 573 708 4.5E-18 T 13-10-2018 IPR010918 PurM-like, C-terminal domain Astex_3071 9ddb3898a63cd71db441a3afb5215a2a 737 Gene3D G3DSA:3.90.650.10 35 371 3.0E-131 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Astex_3071 9ddb3898a63cd71db441a3afb5215a2a 737 SUPERFAMILY SSF55326 21 202 5.98E-52 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Astex_3071 9ddb3898a63cd71db441a3afb5215a2a 737 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 737 319.071 T 13-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 Astex_3071 9ddb3898a63cd71db441a3afb5215a2a 737 Gene3D G3DSA:3.90.650.10 570 736 4.9E-32 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Astex_3071 9ddb3898a63cd71db441a3afb5215a2a 737 SUPERFAMILY SSF56042 573 736 4.04E-33 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Astex_3071 9ddb3898a63cd71db441a3afb5215a2a 737 PIRSF PIRSF001587 6 737 8.6E-289 T 13-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 Astex_3071 9ddb3898a63cd71db441a3afb5215a2a 737 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 24 736 7.5E-284 T 13-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 Astex_0498 63c9c9f87c4278dc368fe88f633df6bb 310 Gene3D G3DSA:3.40.50.1220 183 310 9.2E-55 T 13-10-2018 Astex_0498 63c9c9f87c4278dc368fe88f633df6bb 310 SUPERFAMILY SSF52467 186 309 1.44E-44 T 13-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily Astex_0498 63c9c9f87c4278dc368fe88f633df6bb 310 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 253 279 - T 13-10-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 Astex_0498 63c9c9f87c4278dc368fe88f633df6bb 310 SUPERFAMILY SSF52402 3 181 2.16E-45 T 13-10-2018 Astex_0498 63c9c9f87c4278dc368fe88f633df6bb 310 Pfam PF01012 Electron transfer flavoprotein domain 3 170 1.0E-30 T 13-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 Astex_0498 63c9c9f87c4278dc368fe88f633df6bb 310 PIRSF PIRSF000089 1 310 1.3E-100 T 13-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 Astex_0498 63c9c9f87c4278dc368fe88f633df6bb 310 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 189 272 1.4E-34 T 13-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 Astex_0498 63c9c9f87c4278dc368fe88f633df6bb 310 SMART SM00893 3 181 7.5E-39 T 13-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 Astex_0498 63c9c9f87c4278dc368fe88f633df6bb 310 Gene3D G3DSA:3.40.50.620 2 182 1.3E-45 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Astex_0267 6b4c861ed7f7481d1f9f145492d56b1e 280 Pfam PF01678 Diaminopimelate epimerase 5 125 4.0E-22 T 13-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 Astex_0267 6b4c861ed7f7481d1f9f145492d56b1e 280 Pfam PF01678 Diaminopimelate epimerase 157 271 9.6E-29 T 13-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 Astex_0267 6b4c861ed7f7481d1f9f145492d56b1e 280 Gene3D G3DSA:3.10.310.10 5 276 4.2E-88 T 13-10-2018 Astex_0267 6b4c861ed7f7481d1f9f145492d56b1e 280 Gene3D G3DSA:3.10.310.10 121 270 4.2E-88 T 13-10-2018 Astex_0267 6b4c861ed7f7481d1f9f145492d56b1e 280 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 64 78 - T 13-10-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 Astex_0267 6b4c861ed7f7481d1f9f145492d56b1e 280 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 3 280 34.869 T 13-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 Astex_0267 6b4c861ed7f7481d1f9f145492d56b1e 280 SUPERFAMILY SSF54506 144 278 3.3E-53 T 13-10-2018 Astex_0267 6b4c861ed7f7481d1f9f145492d56b1e 280 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 5 278 6.6E-77 T 13-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 Astex_0267 6b4c861ed7f7481d1f9f145492d56b1e 280 SUPERFAMILY SSF54506 4 132 4.32E-35 T 13-10-2018 Astex_0083 5e2e19f1f0ae2c55f6c4bfb918afd4d2 1168 Pfam PF12705 PD-(D/E)XK nuclease superfamily 996 1142 3.5E-10 T 13-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type Astex_0083 5e2e19f1f0ae2c55f6c4bfb918afd4d2 1168 SUPERFAMILY SSF52540 10 879 7.23E-100 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0083 5e2e19f1f0ae2c55f6c4bfb918afd4d2 1168 TIGRFAM TIGR02784 addA_alphas: double-strand break repair helicase AddA 3 1152 0.0 T 13-10-2018 IPR014151 DNA helicase, AddA type Astex_0083 5e2e19f1f0ae2c55f6c4bfb918afd4d2 1168 SUPERFAMILY SSF52980 998 1133 7.51E-8 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 Astex_0083 5e2e19f1f0ae2c55f6c4bfb918afd4d2 1168 Pfam PF00580 UvrD/REP helicase N-terminal domain 4 452 1.7E-51 T 13-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 Astex_0083 5e2e19f1f0ae2c55f6c4bfb918afd4d2 1168 Pfam PF13361 UvrD-like helicase C-terminal domain 757 870 1.6E-12 T 13-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 Astex_0083 5e2e19f1f0ae2c55f6c4bfb918afd4d2 1168 Gene3D G3DSA:3.40.50.300 739 885 4.1E-19 T 13-10-2018 Astex_0083 5e2e19f1f0ae2c55f6c4bfb918afd4d2 1168 Gene3D G3DSA:3.90.320.10 959 1150 2.1E-6 T 13-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal Astex_0083 5e2e19f1f0ae2c55f6c4bfb918afd4d2 1168 Gene3D G3DSA:3.40.50.300 331 489 3.8E-27 T 13-10-2018 Astex_0083 5e2e19f1f0ae2c55f6c4bfb918afd4d2 1168 Gene3D G3DSA:3.40.50.300 554 659 2.5E-10 T 13-10-2018 Astex_2238 8c8e714762cbf41301cb2d4ab89cc6c1 292 Gene3D G3DSA:2.60.40.2500 165 288 1.3E-23 T 13-10-2018 IPR038161 VirB9/CagX/TrbG, C-terminal domain superfamily Astex_2238 8c8e714762cbf41301cb2d4ab89cc6c1 292 Pfam PF03524 Conjugal transfer protein 34 263 5.0E-40 T 13-10-2018 IPR010258 Conjugal transfer, TrbG/VirB9/CagX Astex_2710 6d8dfa54a21c36f587731ef2f01b6e38 436 Gene3D G3DSA:3.60.15.10 1 234 1.8E-23 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Astex_2710 6d8dfa54a21c36f587731ef2f01b6e38 436 SUPERFAMILY SSF56281 1 242 1.21E-11 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Astex_2710 6d8dfa54a21c36f587731ef2f01b6e38 436 Pfam PF13483 Beta-lactamase superfamily domain 2 130 6.9E-8 T 13-10-2018 Astex_3337 38477d59a7533a35646ad981732a2729 248 SMART SM00345 11 70 1.3E-24 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Astex_3337 38477d59a7533a35646ad981732a2729 248 Gene3D G3DSA:1.20.120.530 87 223 2.0E-26 T 13-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal Astex_3337 38477d59a7533a35646ad981732a2729 248 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 30 44 8.2E-9 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Astex_3337 38477d59a7533a35646ad981732a2729 248 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 60 8.2E-9 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Astex_3337 38477d59a7533a35646ad981732a2729 248 Pfam PF07729 FCD domain 89 212 4.8E-23 T 13-10-2018 IPR011711 GntR, C-terminal Astex_3337 38477d59a7533a35646ad981732a2729 248 SUPERFAMILY SSF46785 3 74 2.39E-22 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_3337 38477d59a7533a35646ad981732a2729 248 SMART SM00895 89 213 3.5E-24 T 13-10-2018 IPR011711 GntR, C-terminal Astex_3337 38477d59a7533a35646ad981732a2729 248 SUPERFAMILY SSF48008 87 220 8.37E-26 T 13-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal Astex_3337 38477d59a7533a35646ad981732a2729 248 Gene3D G3DSA:1.10.10.10 1 74 1.5E-23 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_3337 38477d59a7533a35646ad981732a2729 248 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 70 6.3E-22 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Astex_0815 a10cccf99666855d0b756afbbaddb470 197 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 3 197 31.98 T 13-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 Astex_0815 a10cccf99666855d0b756afbbaddb470 197 Gene3D G3DSA:3.40.50.880 1 197 4.2E-62 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Astex_0815 a10cccf99666855d0b756afbbaddb470 197 PIRSF PIRSF000495 2 197 4.9E-62 T 13-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 Astex_0815 a10cccf99666855d0b756afbbaddb470 197 Pfam PF00117 Glutamine amidotransferase class-I 35 195 3.0E-16 T 13-10-2018 IPR017926 Glutamine amidotransferase Astex_0815 a10cccf99666855d0b756afbbaddb470 197 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 4 196 4.5E-63 T 13-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 Astex_0815 a10cccf99666855d0b756afbbaddb470 197 SUPERFAMILY SSF52317 3 196 5.68E-47 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Astex_1412 551cf20bc4c36eb5785038c12c0e41ae 553 Pfam PF02449 Beta-galactosidase 83 221 3.5E-9 T 13-10-2018 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_1412 551cf20bc4c36eb5785038c12c0e41ae 553 Gene3D G3DSA:2.60.220.20 406 553 1.9E-49 T 13-10-2018 Astex_1412 551cf20bc4c36eb5785038c12c0e41ae 553 SUPERFAMILY SSF51445 56 352 1.77E-40 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_1412 551cf20bc4c36eb5785038c12c0e41ae 553 Gene3D G3DSA:3.20.20.80 33 405 1.8E-138 T 13-10-2018 Astex_0265 4303f7d87410d9bfd67b3d4cdfb44995 675 Pfam PF08495 FIST N domain 59 267 6.6E-23 T 13-10-2018 IPR013702 FIST domain, N-terminal Astex_0265 4303f7d87410d9bfd67b3d4cdfb44995 675 SMART SM00283 455 674 2.1E-9 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_0265 4303f7d87410d9bfd67b3d4cdfb44995 675 Gene3D G3DSA:1.10.287.950 456 673 1.9E-39 T 13-10-2018 Astex_0265 4303f7d87410d9bfd67b3d4cdfb44995 675 SUPERFAMILY SSF58104 450 670 1.83E-43 T 13-10-2018 Astex_0265 4303f7d87410d9bfd67b3d4cdfb44995 675 SMART SM00897 55 277 4.8E-47 T 13-10-2018 IPR013702 FIST domain, N-terminal Astex_0265 4303f7d87410d9bfd67b3d4cdfb44995 675 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 501 664 8.6E-34 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_0265 4303f7d87410d9bfd67b3d4cdfb44995 675 Pfam PF10442 FIST C domain 298 408 1.9E-11 T 13-10-2018 IPR019494 FIST, C-domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 Astex_0265 4303f7d87410d9bfd67b3d4cdfb44995 675 SMART SM01204 284 411 4.7E-20 T 13-10-2018 IPR019494 FIST, C-domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 Astex_0265 4303f7d87410d9bfd67b3d4cdfb44995 675 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 539 566 8.3E-16 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_0265 4303f7d87410d9bfd67b3d4cdfb44995 675 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 568 597 8.3E-16 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_3155 e351480b72f46cead741b5d3ed7c03e4 525 Pfam PF02397 Bacterial sugar transferase 330 518 1.6E-64 T 13-10-2018 IPR003362 Bacterial sugar transferase Astex_3155 e351480b72f46cead741b5d3ed7c03e4 525 Pfam PF13727 CoA-binding domain 119 285 5.4E-16 T 13-10-2018 Astex_3155 e351480b72f46cead741b5d3ed7c03e4 525 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 74 523 9.5E-110 T 13-10-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase Astex_3155 e351480b72f46cead741b5d3ed7c03e4 525 Gene3D G3DSA:3.40.50.720 198 315 1.2E-10 T 13-10-2018 Astex_0118 c5d01996ae749613ec2596ce95f09e67 500 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 6 49 2.3E-16 T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 Astex_0118 c5d01996ae749613ec2596ce95f09e67 500 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 11 496 1.3E-123 T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 Astex_0118 c5d01996ae749613ec2596ce95f09e67 500 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 384 403 - T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 Astex_0118 c5d01996ae749613ec2596ce95f09e67 500 Pfam PF04552 Sigma-54, DNA binding domain 337 497 4.4E-69 T 13-10-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding Astex_0118 c5d01996ae749613ec2596ce95f09e67 500 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 477 484 - T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 Astex_0118 c5d01996ae749613ec2596ce95f09e67 500 Gene3D G3DSA:1.10.10.1330 142 276 8.2E-21 T 13-10-2018 IPR038709 RNA polymerase sigma-54 factor, core-binding domain superfamily Astex_0118 c5d01996ae749613ec2596ce95f09e67 500 Pfam PF04963 Sigma-54 factor, core binding domain 138 322 7.4E-48 T 13-10-2018 IPR007046 RNA polymerase sigma factor 54, core-binding domain GO:0003677|GO:0006352 Astex_0118 c5d01996ae749613ec2596ce95f09e67 500 Gene3D G3DSA:1.10.10.60 437 496 4.6E-20 T 13-10-2018 Astex_0118 c5d01996ae749613ec2596ce95f09e67 500 PRINTS PR00045 Sigma-54 factor signature 412 423 1.2E-30 T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 Astex_0118 c5d01996ae749613ec2596ce95f09e67 500 PRINTS PR00045 Sigma-54 factor signature 396 408 1.2E-30 T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 Astex_0118 c5d01996ae749613ec2596ce95f09e67 500 PRINTS PR00045 Sigma-54 factor signature 472 490 1.2E-30 T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 Astex_0118 c5d01996ae749613ec2596ce95f09e67 500 PRINTS PR00045 Sigma-54 factor signature 208 225 1.2E-30 T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 Astex_0118 c5d01996ae749613ec2596ce95f09e67 500 PIRSF PIRSF000774 1 499 1.4E-141 T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 Astex_1785 a981e7d1a19a8dbb2507397511c0e1b8 378 Gene3D G3DSA:3.40.50.2000 17 362 9.3E-91 T 13-10-2018 Astex_1785 a981e7d1a19a8dbb2507397511c0e1b8 378 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 17 152 3.0E-28 T 13-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Astex_1785 a981e7d1a19a8dbb2507397511c0e1b8 378 SUPERFAMILY SSF53756 17 373 3.14E-96 T 13-10-2018 Astex_1785 a981e7d1a19a8dbb2507397511c0e1b8 378 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 16 372 30.651 T 13-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Astex_1785 a981e7d1a19a8dbb2507397511c0e1b8 378 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 17 367 9.4E-79 T 13-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Astex_1785 a981e7d1a19a8dbb2507397511c0e1b8 378 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 197 362 1.4E-38 T 13-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 Astex_1785 a981e7d1a19a8dbb2507397511c0e1b8 378 Gene3D G3DSA:3.40.50.2000 176 356 9.3E-91 T 13-10-2018 Astex_0239 b0cac21587ff8fc89077235ca4bf5593 396 Pfam PF01734 Patatin-like phospholipase 73 275 3.2E-16 T 13-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 Astex_0239 b0cac21587ff8fc89077235ca4bf5593 396 SUPERFAMILY SSF52151 72 277 2.43E-29 T 13-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase Astex_0239 b0cac21587ff8fc89077235ca4bf5593 396 Gene3D G3DSA:3.40.1090.10 56 180 2.2E-13 T 13-10-2018 Astex_3368 630ed9462d5a4d7eadd4c464036b44ef 206 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 70 167 9.5E-5 T 13-10-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain Astex_3368 630ed9462d5a4d7eadd4c464036b44ef 206 Gene3D G3DSA:1.10.260.40 5 67 1.2E-18 T 13-10-2018 Astex_3368 630ed9462d5a4d7eadd4c464036b44ef 206 Pfam PF00356 Bacterial regulatory proteins, lacI family 13 58 3.0E-14 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Astex_3368 630ed9462d5a4d7eadd4c464036b44ef 206 Gene3D G3DSA:3.40.50.2300 68 202 1.1E-17 T 13-10-2018 Astex_3368 630ed9462d5a4d7eadd4c464036b44ef 206 ProSitePatterns PS00356 LacI-type HTH domain signature. 14 32 - T 13-10-2018 Astex_3368 630ed9462d5a4d7eadd4c464036b44ef 206 SUPERFAMILY SSF53822 68 169 8.01E-9 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Astex_3368 630ed9462d5a4d7eadd4c464036b44ef 206 SUPERFAMILY SSF47413 12 69 6.28E-16 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Astex_3368 630ed9462d5a4d7eadd4c464036b44ef 206 SMART SM00354 11 81 3.5E-23 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Astex_1299 403f220f58c599208a9ee1938f59fc97 50 PIRSF PIRSF037205 3 50 3.8E-21 T 13-10-2018 IPR017136 Uncharacterised conserved protein UCP037205 Astex_1299 403f220f58c599208a9ee1938f59fc97 50 Pfam PF10013 Uncharacterized protein conserved in bacteria (DUF2256) 6 44 2.2E-19 T 13-10-2018 IPR017136 Uncharacterised conserved protein UCP037205 Astex_0483 e521acd56c0a5820bf6c89ac3e708c4b 1023 Pfam PF08238 Sel1 repeat 909 940 0.12 T 13-10-2018 IPR006597 Sel1-like repeat Astex_0483 e521acd56c0a5820bf6c89ac3e708c4b 1023 Pfam PF08238 Sel1 repeat 870 906 8.0E-6 T 13-10-2018 IPR006597 Sel1-like repeat Astex_0483 e521acd56c0a5820bf6c89ac3e708c4b 1023 Pfam PF08238 Sel1 repeat 946 979 4.4E-4 T 13-10-2018 IPR006597 Sel1-like repeat Astex_0483 e521acd56c0a5820bf6c89ac3e708c4b 1023 Gene3D G3DSA:1.25.40.10 774 1009 2.8E-41 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_0483 e521acd56c0a5820bf6c89ac3e708c4b 1023 SUPERFAMILY SSF81901 853 985 1.7E-24 T 13-10-2018 Astex_0483 e521acd56c0a5820bf6c89ac3e708c4b 1023 SMART SM00671 944 979 2.9E-5 T 13-10-2018 IPR006597 Sel1-like repeat Astex_0483 e521acd56c0a5820bf6c89ac3e708c4b 1023 SMART SM00671 908 943 5.1E-4 T 13-10-2018 IPR006597 Sel1-like repeat Astex_0483 e521acd56c0a5820bf6c89ac3e708c4b 1023 SMART SM00671 870 907 0.0059 T 13-10-2018 IPR006597 Sel1-like repeat Astex_3710 572fffa19224b3cfbe7323219876d04f 117 Pfam PF13586 Transposase DDE domain 32 117 7.9E-20 T 13-10-2018 IPR025668 Transposase DDE domain Astex_1962 f642898c1743f6a81a0004c7102f57c6 181 Pfam PF13801 Heavy-metal resistance 22 146 5.3E-29 T 13-10-2018 IPR025961 Heavy-metal resistance protein Astex_0630 781d7f1bd865254112c60a5fdd9f3388 239 Pfam PF03006 Haemolysin-III related 41 227 7.6E-22 T 13-10-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 Astex_1335 790e873c52d9d73831e620a2bd9f27e1 96 Pfam PF04956 TrbC/VIRB2 family 3 91 1.0E-21 T 13-10-2018 IPR007039 Conjugal transfer TrbC/type IV secretion VirB2 Astex_3012 c783787e6dc47dad1d8b80c60c58b291 922 SUPERFAMILY SSF51998 300 503 1.56E-13 T 13-10-2018 Astex_3012 c783787e6dc47dad1d8b80c60c58b291 922 Pfam PF02867 Ribonucleotide reductase, barrel domain 316 520 2.9E-10 T 13-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 Astex_3012 c783787e6dc47dad1d8b80c60c58b291 922 Gene3D G3DSA:3.20.70.20 290 528 6.5E-21 T 13-10-2018 Astex_0431 9c9995d2b1c01b44b27c189361a41b25 464 Pfam PF00425 chorismate binding enzyme 193 452 1.3E-82 T 13-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal Astex_0431 9c9995d2b1c01b44b27c189361a41b25 464 Pfam PF04715 Anthranilate synthase component I, N terminal region 30 147 2.3E-8 T 13-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 Astex_0431 9c9995d2b1c01b44b27c189361a41b25 464 PRINTS PR00095 Anthranilate synthase component I signature 296 309 4.4E-12 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 Astex_0431 9c9995d2b1c01b44b27c189361a41b25 464 PRINTS PR00095 Anthranilate synthase component I signature 310 323 4.4E-12 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 Astex_0431 9c9995d2b1c01b44b27c189361a41b25 464 PRINTS PR00095 Anthranilate synthase component I signature 404 418 4.4E-12 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 Astex_0431 9c9995d2b1c01b44b27c189361a41b25 464 PRINTS PR00095 Anthranilate synthase component I signature 389 403 4.4E-12 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 Astex_0431 9c9995d2b1c01b44b27c189361a41b25 464 Gene3D G3DSA:3.60.120.10 27 463 1.4E-122 T 13-10-2018 IPR005801 ADC synthase GO:0009058 Astex_0431 9c9995d2b1c01b44b27c189361a41b25 464 SUPERFAMILY SSF56322 22 461 1.7E-110 T 13-10-2018 IPR005801 ADC synthase GO:0009058 Astex_2573 bfda62b075d04875311553e2e0ad35d6 205 Pfam PF06577 Protein of unknown function (DUF1134) 45 204 9.9E-67 T 13-10-2018 IPR008325 Uncharacterised conserved protein UCP033924 Astex_0841 0dca4f078196b00b8a7b48449d660184 402 Gene3D G3DSA:3.40.47.10 133 397 7.5E-152 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 Astex_0841 0dca4f078196b00b8a7b48449d660184 402 PIRSF PIRSF000429 4 402 5.0E-127 T 13-10-2018 IPR002155 Thiolase GO:0016747 Astex_0841 0dca4f078196b00b8a7b48449d660184 402 ProSitePatterns PS00737 Thiolases signature 2. 342 358 - T 13-10-2018 IPR020613 Thiolase, conserved site GO:0016747 Astex_0841 0dca4f078196b00b8a7b48449d660184 402 Gene3D G3DSA:3.40.47.10 10 279 7.5E-152 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 Astex_0841 0dca4f078196b00b8a7b48449d660184 402 Pfam PF00108 Thiolase, N-terminal domain 9 265 8.5E-102 T 13-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 Astex_0841 0dca4f078196b00b8a7b48449d660184 402 ProSitePatterns PS00099 Thiolases active site. 382 395 - T 13-10-2018 IPR020610 Thiolase, active site GO:0016747 Astex_0841 0dca4f078196b00b8a7b48449d660184 402 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 89 107 - T 13-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 Astex_0841 0dca4f078196b00b8a7b48449d660184 402 SUPERFAMILY SSF53901 8 272 7.77E-84 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 Astex_0841 0dca4f078196b00b8a7b48449d660184 402 SUPERFAMILY SSF53901 274 399 4.27E-43 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 Astex_0841 0dca4f078196b00b8a7b48449d660184 402 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 11 399 2.7E-141 T 13-10-2018 IPR002155 Thiolase GO:0016747 Astex_0841 0dca4f078196b00b8a7b48449d660184 402 Pfam PF02803 Thiolase, C-terminal domain 273 399 3.5E-49 T 13-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 Astex_2842 0426cccde301b5b0b33069d4b83ef70a 1142 SUPERFAMILY SSF89550 14 271 7.85E-7 T 13-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 Astex_2842 0426cccde301b5b0b33069d4b83ef70a 1142 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 5 1021 0.0 T 13-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Astex_2842 0426cccde301b5b0b33069d4b83ef70a 1142 Gene3D G3DSA:3.20.20.140 1 277 2.2E-70 T 13-10-2018 Astex_2842 0426cccde301b5b0b33069d4b83ef70a 1142 Pfam PF14579 Helix-hairpin-helix motif 802 890 5.0E-29 T 13-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Astex_2842 0426cccde301b5b0b33069d4b83ef70a 1142 SMART SM00481 6 73 9.9E-15 T 13-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal Astex_2842 0426cccde301b5b0b33069d4b83ef70a 1142 Gene3D G3DSA:1.10.10.1600 437 516 4.2E-25 T 13-10-2018 Astex_2842 0426cccde301b5b0b33069d4b83ef70a 1142 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 300 729 5.3E-168 T 13-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Astex_2842 0426cccde301b5b0b33069d4b83ef70a 1142 Pfam PF02811 PHP domain 7 177 2.7E-32 T 13-10-2018 IPR004013 PHP domain GO:0003824 Astex_2842 0426cccde301b5b0b33069d4b83ef70a 1142 Gene3D G3DSA:1.10.150.870 773 879 1.6E-5 T 13-10-2018 Astex_2842 0426cccde301b5b0b33069d4b83ef70a 1142 Pfam PF01336 OB-fold nucleic acid binding domain 986 1058 6.5E-7 T 13-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 Astex_2471 0221a8cefcd43a2edd7f8684ded3e6c0 402 Gene3D G3DSA:2.102.10.10 47 166 2.5E-66 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 Astex_2471 0221a8cefcd43a2edd7f8684ded3e6c0 402 SUPERFAMILY SSF50022 21 161 1.7E-48 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 Astex_2471 0221a8cefcd43a2edd7f8684ded3e6c0 402 SUPERFAMILY SSF55961 162 383 7.06E-29 T 13-10-2018 Astex_2471 0221a8cefcd43a2edd7f8684ded3e6c0 402 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 196 383 8.5E-30 T 13-10-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0044237|GO:0051537|GO:0055114 Astex_2471 0221a8cefcd43a2edd7f8684ded3e6c0 402 Gene3D G3DSA:3.90.380.10 25 379 2.5E-66 T 13-10-2018 Astex_2471 0221a8cefcd43a2edd7f8684ded3e6c0 402 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 92 114 - T 13-10-2018 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0051537|GO:0055114 Astex_2471 0221a8cefcd43a2edd7f8684ded3e6c0 402 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 146 172 4.6E-23 T 13-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 Astex_2471 0221a8cefcd43a2edd7f8684ded3e6c0 402 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 184 206 4.6E-23 T 13-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 Astex_2471 0221a8cefcd43a2edd7f8684ded3e6c0 402 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 105 125 4.6E-23 T 13-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 Astex_2471 0221a8cefcd43a2edd7f8684ded3e6c0 402 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 34 59 4.6E-23 T 13-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 Astex_2471 0221a8cefcd43a2edd7f8684ded3e6c0 402 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 64 79 4.6E-23 T 13-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 Astex_2471 0221a8cefcd43a2edd7f8684ded3e6c0 402 Pfam PF00355 Rieske [2Fe-2S] domain 49 133 2.4E-19 T 13-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Astex_1498 a3de740501b0a44931e6d25e3e940fbc 382 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 213 340 6.3E-17 T 13-10-2018 IPR006342 Methyltransferase FkbM Astex_1498 a3de740501b0a44931e6d25e3e940fbc 382 SUPERFAMILY SSF53335 9 381 9.14E-71 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Astex_1498 a3de740501b0a44931e6d25e3e940fbc 382 Pfam PF05050 Methyltransferase FkbM domain 216 340 1.6E-12 T 13-10-2018 IPR006342 Methyltransferase FkbM Astex_1498 a3de740501b0a44931e6d25e3e940fbc 382 Gene3D G3DSA:3.40.50.720 27 137 5.2E-6 T 13-10-2018 Astex_1498 a3de740501b0a44931e6d25e3e940fbc 382 Gene3D G3DSA:3.40.50.150 194 381 6.0E-47 T 13-10-2018 Astex_0099 8eb9c6ff7676367b51e9aa9d239331fb 360 Pfam PF12802 MarR family 5 53 1.2E-7 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Astex_0099 8eb9c6ff7676367b51e9aa9d239331fb 360 SUPERFAMILY SSF46785 5 72 1.13E-11 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_0099 8eb9c6ff7676367b51e9aa9d239331fb 360 Gene3D G3DSA:1.10.10.10 6 74 3.4E-14 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_0099 8eb9c6ff7676367b51e9aa9d239331fb 360 SUPERFAMILY SSF53067 80 351 7.07E-21 T 13-10-2018 Astex_0099 8eb9c6ff7676367b51e9aa9d239331fb 360 Gene3D G3DSA:3.30.420.40 92 348 2.7E-20 T 13-10-2018 Astex_0099 8eb9c6ff7676367b51e9aa9d239331fb 360 Pfam PF00480 ROK family 96 232 1.8E-6 T 13-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 Astex_0099 8eb9c6ff7676367b51e9aa9d239331fb 360 Gene3D G3DSA:3.30.420.40 201 335 2.7E-20 T 13-10-2018 Astex_2116 46f965e1bcde051f0956bde1907a8d2a 973 Gene3D G3DSA:2.170.130.10 33 180 2.4E-15 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_2116 46f965e1bcde051f0956bde1907a8d2a 973 Gene3D G3DSA:2.40.170.20 310 973 7.8E-26 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_2116 46f965e1bcde051f0956bde1907a8d2a 973 SUPERFAMILY SSF56935 34 973 1.87E-71 T 13-10-2018 Astex_2116 46f965e1bcde051f0956bde1907a8d2a 973 Pfam PF07715 TonB-dependent Receptor Plug Domain 61 174 2.2E-14 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_2116 46f965e1bcde051f0956bde1907a8d2a 973 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 42 973 6.3E-187 T 13-10-2018 IPR010104 Bacterial TonB-dependent receptor Astex_2116 46f965e1bcde051f0956bde1907a8d2a 973 Pfam PF00593 TonB dependent receptor 457 972 3.6E-24 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_1982 dca0cf5c9bf52947248d77503d0d25e1 102 Gene3D G3DSA:3.30.70.100 1 94 1.0E-14 T 13-10-2018 Astex_1982 dca0cf5c9bf52947248d77503d0d25e1 102 SMART SM00886 2 94 6.6E-19 T 13-10-2018 IPR013097 Stress responsive alpha-beta barrel Astex_1982 dca0cf5c9bf52947248d77503d0d25e1 102 Pfam PF07876 Stress responsive A/B Barrel Domain 2 94 5.0E-20 T 13-10-2018 IPR013097 Stress responsive alpha-beta barrel Astex_1982 dca0cf5c9bf52947248d77503d0d25e1 102 SUPERFAMILY SSF54909 1 96 6.33E-21 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel Astex_1653 fad73b578d7ab819cfc471180ea0d238 346 Pfam PF01116 Fructose-bisphosphate aldolase class-II 5 327 3.0E-91 T 13-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 Astex_1653 fad73b578d7ab819cfc471180ea0d238 346 SUPERFAMILY SSF51569 3 328 3.96E-101 T 13-10-2018 Astex_1653 fad73b578d7ab819cfc471180ea0d238 346 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 73 85 - T 13-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 Astex_1653 fad73b578d7ab819cfc471180ea0d238 346 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 139 150 - T 13-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 Astex_1653 fad73b578d7ab819cfc471180ea0d238 346 PIRSF PIRSF001359 1 329 1.2E-81 T 13-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 Astex_1653 fad73b578d7ab819cfc471180ea0d238 346 TIGRFAM TIGR01521 FruBisAldo_II_B: fructose-bisphosphate aldolase, class II, Calvin cycle subtype 3 344 9.9E-188 T 13-10-2018 IPR006412 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 Astex_1653 fad73b578d7ab819cfc471180ea0d238 346 Gene3D G3DSA:3.20.20.70 1 345 3.1E-136 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_1653 fad73b578d7ab819cfc471180ea0d238 346 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 3 329 1.7E-97 T 13-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 Astex_3613 78ca5d6401de3acfc36caf32a6074bb9 305 Gene3D G3DSA:2.115.10.20 12 304 2.7E-83 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Astex_3613 78ca5d6401de3acfc36caf32a6074bb9 305 Pfam PF04616 Glycosyl hydrolases family 43 21 298 1.0E-43 T 13-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 Astex_3613 78ca5d6401de3acfc36caf32a6074bb9 305 SUPERFAMILY SSF75005 7 298 7.57E-64 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Astex_1120 08681e6a87e5b4f0054b072ccb093322 231 Gene3D G3DSA:3.40.30.10 36 231 1.6E-37 T 13-10-2018 Astex_1120 08681e6a87e5b4f0054b072ccb093322 231 Pfam PF13462 Thioredoxin 53 228 6.0E-33 T 13-10-2018 IPR012336 Thioredoxin-like fold Astex_1120 08681e6a87e5b4f0054b072ccb093322 231 SUPERFAMILY SSF52833 53 227 3.56E-29 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Astex_0786 d2842af21a2cbe1925c158bdab50e52e 455 SUPERFAMILY SSF53474 129 452 5.99E-45 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_0786 d2842af21a2cbe1925c158bdab50e52e 455 Pfam PF12146 Serine aminopeptidase, S33 192 418 6.7E-16 T 13-10-2018 IPR022742 Serine aminopeptidase, S33 Astex_0984 c742031b28b22ed2059625605097dac0 555 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Astex_0984 c742031b28b22ed2059625605097dac0 555 SMART SM00382 32 277 2.1E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_0984 c742031b28b22ed2059625605097dac0 555 SMART SM00382 348 524 1.9E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_0984 c742031b28b22ed2059625605097dac0 555 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 3 552 1.5E-283 T 13-10-2018 IPR022374 Energy-dependent translational throttle protein EttA GO:0045900 Astex_0984 c742031b28b22ed2059625605097dac0 555 Gene3D G3DSA:3.40.50.300 285 554 1.6E-70 T 13-10-2018 Astex_0984 c742031b28b22ed2059625605097dac0 555 SUPERFAMILY SSF52540 9 242 2.22E-46 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0984 c742031b28b22ed2059625605097dac0 555 Pfam PF00005 ABC transporter 24 189 3.6E-26 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_0984 c742031b28b22ed2059625605097dac0 555 Pfam PF00005 ABC transporter 340 473 4.3E-23 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_0984 c742031b28b22ed2059625605097dac0 555 SUPERFAMILY SSF52540 300 522 4.39E-47 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0984 c742031b28b22ed2059625605097dac0 555 Gene3D G3DSA:3.40.50.300 2 283 2.5E-73 T 13-10-2018 Astex_0984 c742031b28b22ed2059625605097dac0 555 Pfam PF12848 ABC transporter 228 302 2.8E-12 T 13-10-2018 IPR032781 ABC-transporter extension domain Astex_0693 7837fcaa905e808bf3002d5e1bb3e02f 189 Pfam PF01339 CheB methylesterase 9 184 1.6E-51 T 13-10-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 Astex_0693 7837fcaa905e808bf3002d5e1bb3e02f 189 Gene3D G3DSA:3.40.50.180 2 189 3.4E-58 T 13-10-2018 IPR035909 Methylesterase CheB, C-terminal Astex_0693 7837fcaa905e808bf3002d5e1bb3e02f 189 SUPERFAMILY SSF52738 6 186 6.02E-55 T 13-10-2018 IPR035909 Methylesterase CheB, C-terminal Astex_2757 dbdc03c62ff1148e8b933e7ac7c79273 376 Gene3D G3DSA:3.30.420.40 151 329 3.9E-98 T 13-10-2018 Astex_2757 dbdc03c62ff1148e8b933e7ac7c79273 376 Pfam PF03702 Anhydro-N-acetylmuramic acid kinase 2 368 1.9E-78 T 13-10-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 MetaCyc: PWY-7883 Astex_2757 dbdc03c62ff1148e8b933e7ac7c79273 376 SUPERFAMILY SSF53067 1 332 7.87E-20 T 13-10-2018 Astex_2757 dbdc03c62ff1148e8b933e7ac7c79273 376 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 1 369 34.394 T 13-10-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 MetaCyc: PWY-7883 Astex_2757 dbdc03c62ff1148e8b933e7ac7c79273 376 Gene3D G3DSA:3.30.420.40 4 360 3.9E-98 T 13-10-2018 Astex_1532 fe5fb0986e3ae1c5c7dab66164ed4781 206 SUPERFAMILY SSF109604 24 199 7.33E-15 T 13-10-2018 Astex_1532 fe5fb0986e3ae1c5c7dab66164ed4781 206 PIRSF PIRSF035170 15 206 8.2E-40 T 13-10-2018 IPR009218 Predicted HD phosphohydrolase Astex_1896 181ce3dff2da288b67e61ed6e88b8393 484 Gene3D G3DSA:3.20.20.60 7 334 2.0E-167 T 13-10-2018 Astex_1896 181ce3dff2da288b67e61ed6e88b8393 484 SUPERFAMILY SSF52935 322 472 2.49E-37 T 13-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Astex_1896 181ce3dff2da288b67e61ed6e88b8393 484 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 7 472 7.3E-153 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Astex_1896 181ce3dff2da288b67e61ed6e88b8393 484 Gene3D G3DSA:2.40.33.10 75 171 2.0E-167 T 13-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Astex_1896 181ce3dff2da288b67e61ed6e88b8393 484 SUPERFAMILY SSF51621 5 341 1.26E-95 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 Astex_1896 181ce3dff2da288b67e61ed6e88b8393 484 Pfam PF00224 Pyruvate kinase, barrel domain 7 336 7.1E-113 T 13-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Astex_1896 181ce3dff2da288b67e61ed6e88b8393 484 Gene3D G3DSA:3.40.1380.20 335 468 2.0E-167 T 13-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Astex_1896 181ce3dff2da288b67e61ed6e88b8393 484 SUPERFAMILY SSF50800 75 170 2.44E-24 T 13-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily Astex_1896 181ce3dff2da288b67e61ed6e88b8393 484 PRINTS PR01050 Pyruvate kinase family signature 243 267 4.2E-66 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Astex_1896 181ce3dff2da288b67e61ed6e88b8393 484 PRINTS PR01050 Pyruvate kinase family signature 189 203 4.2E-66 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Astex_1896 181ce3dff2da288b67e61ed6e88b8393 484 PRINTS PR01050 Pyruvate kinase family signature 268 292 4.2E-66 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Astex_1896 181ce3dff2da288b67e61ed6e88b8393 484 PRINTS PR01050 Pyruvate kinase family signature 64 80 4.2E-66 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Astex_1896 181ce3dff2da288b67e61ed6e88b8393 484 PRINTS PR01050 Pyruvate kinase family signature 216 242 4.2E-66 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Astex_1896 181ce3dff2da288b67e61ed6e88b8393 484 PRINTS PR01050 Pyruvate kinase family signature 293 311 4.2E-66 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Astex_1896 181ce3dff2da288b67e61ed6e88b8393 484 PRINTS PR01050 Pyruvate kinase family signature 312 328 4.2E-66 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Astex_1896 181ce3dff2da288b67e61ed6e88b8393 484 Pfam PF02887 Pyruvate kinase, alpha/beta domain 358 469 6.8E-30 T 13-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Astex_1896 181ce3dff2da288b67e61ed6e88b8393 484 ProSitePatterns PS00110 Pyruvate kinase active site signature. 214 226 - T 13-10-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 Astex_1214 a07e2927982b5ad1836fb98bb17a9f3d 335 Pfam PF13377 Periplasmic binding protein-like domain 170 332 1.5E-34 T 13-10-2018 Astex_1214 a07e2927982b5ad1836fb98bb17a9f3d 335 SUPERFAMILY SSF47413 5 63 2.72E-15 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Astex_1214 a07e2927982b5ad1836fb98bb17a9f3d 335 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 50 3.4E-14 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Astex_1214 a07e2927982b5ad1836fb98bb17a9f3d 335 Gene3D G3DSA:1.10.260.40 1 57 3.9E-19 T 13-10-2018 Astex_1214 a07e2927982b5ad1836fb98bb17a9f3d 335 SUPERFAMILY SSF53822 64 332 2.36E-67 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Astex_1214 a07e2927982b5ad1836fb98bb17a9f3d 335 SMART SM00354 4 74 3.6E-21 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 Astex_1214 a07e2927982b5ad1836fb98bb17a9f3d 335 Gene3D G3DSA:3.40.50.2300 58 304 1.7E-74 T 13-10-2018 Astex_1214 a07e2927982b5ad1836fb98bb17a9f3d 335 ProSitePatterns PS00356 LacI-type HTH domain signature. 7 25 - T 13-10-2018 Astex_1214 a07e2927982b5ad1836fb98bb17a9f3d 335 Gene3D G3DSA:3.40.50.2300 162 288 1.7E-74 T 13-10-2018 Astex_2986 4f9eedbe248b57f13fb74b25bbb5b830 101 Gene3D G3DSA:3.30.1050.10 3 101 3.3E-18 T 13-10-2018 IPR036527 SCP2 sterol-binding domain superfamily Astex_2986 4f9eedbe248b57f13fb74b25bbb5b830 101 SUPERFAMILY SSF55718 6 100 3.06E-19 T 13-10-2018 IPR036527 SCP2 sterol-binding domain superfamily Astex_2986 4f9eedbe248b57f13fb74b25bbb5b830 101 Pfam PF02036 SCP-2 sterol transfer family 23 100 8.9E-16 T 13-10-2018 IPR003033 SCP2 sterol-binding domain Astex_2634 04857972c7cb507cc2b286d5a43f78d2 241 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 15 231 3.5E-59 T 13-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 Astex_2634 04857972c7cb507cc2b286d5a43f78d2 241 Pfam PF06508 Queuosine biosynthesis protein QueC 15 238 2.0E-69 T 13-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 Astex_2634 04857972c7cb507cc2b286d5a43f78d2 241 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 13 241 48.076 T 13-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 Astex_2634 04857972c7cb507cc2b286d5a43f78d2 241 PIRSF PIRSF006293 11 241 2.4E-64 T 13-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 Astex_2634 04857972c7cb507cc2b286d5a43f78d2 241 Gene3D G3DSA:3.40.50.620 13 241 5.3E-64 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Astex_2634 04857972c7cb507cc2b286d5a43f78d2 241 SUPERFAMILY SSF52402 15 238 7.54E-52 T 13-10-2018 Astex_1194 dacb2d71da7c09cf6a8e0de139f69ce9 190 PIRSF PIRSF006305 1 190 1.3E-44 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 Astex_1194 dacb2d71da7c09cf6a8e0de139f69ce9 190 TIGRFAM TIGR00172 maf: septum formation protein Maf 3 184 4.2E-45 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 Astex_1194 dacb2d71da7c09cf6a8e0de139f69ce9 190 SUPERFAMILY SSF52972 2 184 1.96E-54 T 13-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like Astex_1194 dacb2d71da7c09cf6a8e0de139f69ce9 190 Hamap MF_00528 Septum formation protein Maf [maf]. 3 190 31.065 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 Astex_1194 dacb2d71da7c09cf6a8e0de139f69ce9 190 Gene3D G3DSA:3.90.950.10 3 189 8.5E-58 T 13-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like Astex_1194 dacb2d71da7c09cf6a8e0de139f69ce9 190 Pfam PF02545 Maf-like protein 4 184 1.2E-48 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 Astex_0505 39d097dd4a423659a99afa0ad65b07f1 438 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 7 424 2.1E-138 T 13-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Astex_0505 39d097dd4a423659a99afa0ad65b07f1 438 Gene3D G3DSA:2.40.37.10 16 421 2.0E-138 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Astex_0505 39d097dd4a423659a99afa0ad65b07f1 438 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 15 425 40.199 T 13-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Astex_0505 39d097dd4a423659a99afa0ad65b07f1 438 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 30 382 6.8E-29 T 13-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 Astex_0505 39d097dd4a423659a99afa0ad65b07f1 438 PRINTS PR01181 Diaminopimelate decarboxylase signature 173 182 3.4E-23 T 13-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Astex_0505 39d097dd4a423659a99afa0ad65b07f1 438 PRINTS PR01181 Diaminopimelate decarboxylase signature 392 414 3.4E-23 T 13-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Astex_0505 39d097dd4a423659a99afa0ad65b07f1 438 PRINTS PR01181 Diaminopimelate decarboxylase signature 310 328 3.4E-23 T 13-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Astex_0505 39d097dd4a423659a99afa0ad65b07f1 438 PRINTS PR01181 Diaminopimelate decarboxylase signature 84 101 3.4E-23 T 13-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Astex_0505 39d097dd4a423659a99afa0ad65b07f1 438 Gene3D G3DSA:3.20.20.10 34 285 2.0E-138 T 13-10-2018 IPR029066 PLP-binding barrel Astex_0505 39d097dd4a423659a99afa0ad65b07f1 438 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 66 84 - T 13-10-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site Astex_0505 39d097dd4a423659a99afa0ad65b07f1 438 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 382 395 1.4E-21 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Astex_0505 39d097dd4a423659a99afa0ad65b07f1 438 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 66 84 1.4E-21 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Astex_0505 39d097dd4a423659a99afa0ad65b07f1 438 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 199 212 1.4E-21 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Astex_0505 39d097dd4a423659a99afa0ad65b07f1 438 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 280 299 1.4E-21 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Astex_0505 39d097dd4a423659a99afa0ad65b07f1 438 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 86 98 1.4E-21 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Astex_0505 39d097dd4a423659a99afa0ad65b07f1 438 SUPERFAMILY SSF50621 265 428 8.79E-52 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Astex_0505 39d097dd4a423659a99afa0ad65b07f1 438 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 63 290 4.4E-55 T 13-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 Astex_0505 39d097dd4a423659a99afa0ad65b07f1 438 SUPERFAMILY SSF51419 26 292 2.18E-73 T 13-10-2018 IPR029066 PLP-binding barrel Astex_2368 50117bcd906086521a289e3cb8a9950a 91 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 6 72 1.8E-15 T 13-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM Astex_2368 50117bcd906086521a289e3cb8a9950a 91 SUPERFAMILY SSF143120 6 78 6.8E-16 T 13-10-2018 IPR036165 YefM-like superfamily Astex_2368 50117bcd906086521a289e3cb8a9950a 91 Gene3D G3DSA:3.40.1620.10 5 43 2.1E-5 T 13-10-2018 Astex_2368 50117bcd906086521a289e3cb8a9950a 91 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 9 58 2.0E-9 T 13-10-2018 Astex_3349 c87832a293e9eafcda14e81febb60147 256 SUPERFAMILY SSF52317 70 251 1.4E-32 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Astex_3349 c87832a293e9eafcda14e81febb60147 256 Pfam PF06283 Trehalose utilisation 27 248 3.8E-47 T 13-10-2018 IPR029010 ThuA-like domain Astex_3349 c87832a293e9eafcda14e81febb60147 256 Gene3D G3DSA:3.40.50.880 13 253 4.6E-54 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Astex_1234 de5065f1fe0d9fca7fc1e8d0be31057f 269 Pfam PF00005 ABC transporter 25 167 2.0E-31 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_1234 de5065f1fe0d9fca7fc1e8d0be31057f 269 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Astex_1234 de5065f1fe0d9fca7fc1e8d0be31057f 269 Gene3D G3DSA:3.40.50.300 3 254 8.4E-61 T 13-10-2018 Astex_1234 de5065f1fe0d9fca7fc1e8d0be31057f 269 TIGRFAM TIGR01184 ntrCD: nitrate ABC transporter, ATP-binding proteins C and D 25 255 3.0E-97 T 13-10-2018 IPR005890 Nitrate transport ATP-binding subunit C/D GO:0015112|GO:0015706|GO:0016020 Astex_1234 de5065f1fe0d9fca7fc1e8d0be31057f 269 SUPERFAMILY SSF52540 6 229 8.75E-67 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1234 de5065f1fe0d9fca7fc1e8d0be31057f 269 SMART SM00382 34 217 5.7E-16 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_2097 0d6ff19ae16c26745b7eddfe592c3894 477 Gene3D G3DSA:3.40.309.10 251 443 7.4E-154 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 Astex_2097 0d6ff19ae16c26745b7eddfe592c3894 477 Pfam PF00171 Aldehyde dehydrogenase family 17 471 1.1E-152 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 Astex_2097 0d6ff19ae16c26745b7eddfe592c3894 477 SUPERFAMILY SSF53720 3 473 1.7E-151 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 Astex_2097 0d6ff19ae16c26745b7eddfe592c3894 477 Gene3D G3DSA:3.40.605.10 12 467 7.4E-154 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 Astex_3649 9bae7d0e7f0610cdfab07d33b30feba9 259 Pfam PF00005 ABC transporter 20 169 4.9E-29 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_3649 9bae7d0e7f0610cdfab07d33b30feba9 259 SMART SM00382 29 230 7.8E-16 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_3649 9bae7d0e7f0610cdfab07d33b30feba9 259 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Astex_3649 9bae7d0e7f0610cdfab07d33b30feba9 259 SUPERFAMILY SSF52540 4 220 1.33E-60 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_3649 9bae7d0e7f0610cdfab07d33b30feba9 259 Gene3D G3DSA:3.40.50.300 1 243 7.4E-59 T 13-10-2018 Astex_2195 81e1cde310e27aed93c739838ec73879 114 Pfam PF05717 IS66 Orf2 like protein 7 103 5.0E-32 T 13-10-2018 IPR008878 Transposase IS66, Orf2 Astex_3050 81e1cde310e27aed93c739838ec73879 114 Pfam PF05717 IS66 Orf2 like protein 7 103 5.0E-32 T 13-10-2018 IPR008878 Transposase IS66, Orf2 Astex_2610 3b029d204e37b500bdbe0d75ce0819a3 248 PIRSF PIRSF015601 1 247 1.7E-53 T 13-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 Astex_2610 3b029d204e37b500bdbe0d75ce0819a3 248 SUPERFAMILY SSF88697 2 72 1.74E-13 T 13-10-2018 IPR015947 PUA-like superfamily Astex_2610 3b029d204e37b500bdbe0d75ce0819a3 248 Gene3D G3DSA:2.40.240.20 3 73 6.4E-21 T 13-10-2018 Astex_2610 3b029d204e37b500bdbe0d75ce0819a3 248 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 19 243 1.1E-39 T 13-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 Astex_2610 3b029d204e37b500bdbe0d75ce0819a3 248 SUPERFAMILY SSF75217 83 247 2.01E-36 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases Astex_2610 3b029d204e37b500bdbe0d75ce0819a3 248 Gene3D G3DSA:3.40.1280.10 78 248 2.8E-43 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Astex_2610 3b029d204e37b500bdbe0d75ce0819a3 248 Pfam PF04452 RNA methyltransferase 21 241 1.0E-52 T 13-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 Astex_3822 1d45b5dd07f418b4b2b6c4588aa48511 308 SUPERFAMILY SSF52788 1 135 2.49E-36 T 13-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily Astex_3822 1d45b5dd07f418b4b2b6c4588aa48511 308 SMART SM00226 1 135 4.6E-37 T 13-10-2018 IPR023485 Phosphotyrosine protein phosphatase I Astex_3822 1d45b5dd07f418b4b2b6c4588aa48511 308 Pfam PF00583 Acetyltransferase (GNAT) family 201 270 1.4E-4 T 13-10-2018 IPR000182 GNAT domain Astex_3822 1d45b5dd07f418b4b2b6c4588aa48511 308 Gene3D G3DSA:3.40.630.30 157 291 1.7E-15 T 13-10-2018 Astex_3822 1d45b5dd07f418b4b2b6c4588aa48511 308 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 3 133 2.5E-18 T 13-10-2018 IPR023485 Phosphotyrosine protein phosphatase I Astex_3822 1d45b5dd07f418b4b2b6c4588aa48511 308 SUPERFAMILY SSF55729 193 273 1.72E-12 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Astex_3822 1d45b5dd07f418b4b2b6c4588aa48511 308 Gene3D G3DSA:3.40.50.2300 1 135 4.2E-36 T 13-10-2018 Astex_1647 a17c85b0f1d912a2115f7bd87c361685 233 Gene3D G3DSA:3.30.70.580 61 226 3.9E-52 T 13-10-2018 Astex_1647 a17c85b0f1d912a2115f7bd87c361685 233 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 99 113 - T 13-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 Astex_1647 a17c85b0f1d912a2115f7bd87c361685 233 Gene3D G3DSA:3.30.70.1560 128 210 3.9E-52 T 13-10-2018 Astex_1647 a17c85b0f1d912a2115f7bd87c361685 233 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 64 223 3.7E-40 T 13-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 Astex_1647 a17c85b0f1d912a2115f7bd87c361685 233 Pfam PF00849 RNA pseudouridylate synthase 60 193 1.7E-17 T 13-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 Astex_1647 a17c85b0f1d912a2115f7bd87c361685 233 Gene3D G3DSA:3.10.290.10 1 54 1.1E-6 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 Astex_1647 a17c85b0f1d912a2115f7bd87c361685 233 SUPERFAMILY SSF55120 59 227 4.64E-39 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 Astex_2050 23333871b18dece043158e0de1ac4464 429 Gene3D G3DSA:3.50.50.60 33 386 9.1E-68 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_2050 23333871b18dece043158e0de1ac4464 429 Pfam PF01266 FAD dependent oxidoreductase 33 384 2.2E-45 T 13-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 Astex_2050 23333871b18dece043158e0de1ac4464 429 SUPERFAMILY SSF51905 32 400 8.42E-43 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_2050 23333871b18dece043158e0de1ac4464 429 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 33 55 9.2E-5 T 13-10-2018 Astex_2050 23333871b18dece043158e0de1ac4464 429 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 381 396 9.2E-5 T 13-10-2018 Astex_2050 23333871b18dece043158e0de1ac4464 429 Gene3D G3DSA:3.30.9.10 126 347 9.1E-68 T 13-10-2018 Astex_2965 cdef6d31cc2f825d43206d32162ecf1f 196 Pfam PF00156 Phosphoribosyl transferase domain 46 171 2.5E-16 T 13-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 Astex_2965 cdef6d31cc2f825d43206d32162ecf1f 196 SUPERFAMILY SSF53271 2 182 5.96E-36 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like Astex_2965 cdef6d31cc2f825d43206d32162ecf1f 196 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 196 25.47 T 13-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Astex_2965 cdef6d31cc2f825d43206d32162ecf1f 196 TIGRFAM TIGR01367 pyrE_Therm: orotate phosphoribosyltransferase 5 190 1.4E-79 T 13-10-2018 IPR006273 Orotate phosphoribosyltransferase, bacterial GO:0004588|GO:0019856 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 Astex_2965 cdef6d31cc2f825d43206d32162ecf1f 196 Gene3D G3DSA:3.40.50.2020 5 193 1.9E-51 T 13-10-2018 Astex_0391 a5bde8352d764b280beccc92a5cb77c7 141 Pfam PF13673 Acetyltransferase (GNAT) domain 48 127 4.1E-16 T 13-10-2018 IPR000182 GNAT domain Astex_0391 a5bde8352d764b280beccc92a5cb77c7 141 SUPERFAMILY SSF55729 2 139 9.98E-28 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Astex_0391 a5bde8352d764b280beccc92a5cb77c7 141 Gene3D G3DSA:3.40.630.30 1 141 2.5E-35 T 13-10-2018 Astex_1630 8bb0e7f084f39a0198da2bdafbdd2aa1 387 Hamap MF_02079 Peptidoglycan glycosyltransferase MrdB [mrdB]. 17 375 26.709 T 13-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Astex_1630 8bb0e7f084f39a0198da2bdafbdd2aa1 387 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 23 372 2.6E-123 T 13-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Astex_1630 8bb0e7f084f39a0198da2bdafbdd2aa1 387 Pfam PF01098 Cell cycle protein 29 372 2.5E-94 T 13-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Astex_1114 a812128281c2fd23bc0e60f94432f9fa 214 Hamap MF_01398 ATP synthase subunit b [atpF]. 60 200 10.634 T 13-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 Astex_1114 a812128281c2fd23bc0e60f94432f9fa 214 Pfam PF00430 ATP synthase B/B' CF(0) 69 197 1.4E-16 T 13-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 Astex_3566 a032a591878dae2e74b68b710e6ae109 321 Pfam PF13602 Zinc-binding dehydrogenase 176 316 2.6E-15 T 13-10-2018 Astex_3566 a032a591878dae2e74b68b710e6ae109 321 SUPERFAMILY SSF50129 4 125 8.52E-31 T 13-10-2018 IPR011032 GroES-like superfamily Astex_3566 a032a591878dae2e74b68b710e6ae109 321 Gene3D G3DSA:3.90.180.10 4 316 5.8E-101 T 13-10-2018 Astex_3566 a032a591878dae2e74b68b710e6ae109 321 SUPERFAMILY SSF51735 99 269 1.6E-32 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_3566 a032a591878dae2e74b68b710e6ae109 321 SMART SM00829 1 316 2.2E-8 T 13-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Astex_3566 a032a591878dae2e74b68b710e6ae109 321 TIGRFAM TIGR02817 adh_fam_1: zinc-binding alcohol dehydrogenase family protein 4 319 6.4E-143 T 13-10-2018 IPR014182 Alcohol dehydrogenase, zinc-binding type 1 GO:0008270 Astex_3566 a032a591878dae2e74b68b710e6ae109 321 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 13 72 3.3E-7 T 13-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Astex_3566 a032a591878dae2e74b68b710e6ae109 321 Gene3D G3DSA:3.40.50.720 110 255 5.8E-101 T 13-10-2018 Astex_2794 55736cabc5605dcf95fc877c75fe4b45 167 Pfam PF00034 Cytochrome c 65 159 3.9E-7 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_2794 55736cabc5605dcf95fc877c75fe4b45 167 PRINTS PR00604 Class IA and IB cytochrome C signature 152 160 3.2E-21 T 13-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_2794 55736cabc5605dcf95fc877c75fe4b45 167 PRINTS PR00604 Class IA and IB cytochrome C signature 135 145 3.2E-21 T 13-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_2794 55736cabc5605dcf95fc877c75fe4b45 167 PRINTS PR00604 Class IA and IB cytochrome C signature 102 112 3.2E-21 T 13-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_2794 55736cabc5605dcf95fc877c75fe4b45 167 PRINTS PR00604 Class IA and IB cytochrome C signature 86 101 3.2E-21 T 13-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_2794 55736cabc5605dcf95fc877c75fe4b45 167 PRINTS PR00604 Class IA and IB cytochrome C signature 116 132 3.2E-21 T 13-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_2794 55736cabc5605dcf95fc877c75fe4b45 167 PRINTS PR00604 Class IA and IB cytochrome C signature 73 80 3.2E-21 T 13-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_2794 55736cabc5605dcf95fc877c75fe4b45 167 SUPERFAMILY SSF46626 61 159 7.68E-32 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Astex_2794 55736cabc5605dcf95fc877c75fe4b45 167 Gene3D G3DSA:1.10.760.10 19 160 3.8E-42 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Astex_0365 6b12e466dbd050fe5e242e542850c5e8 155 Pfam PF00072 Response regulator receiver domain 8 121 3.5E-13 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_0365 6b12e466dbd050fe5e242e542850c5e8 155 SUPERFAMILY SSF52172 5 132 1.71E-23 T 13-10-2018 IPR011006 CheY-like superfamily Astex_0365 6b12e466dbd050fe5e242e542850c5e8 155 Gene3D G3DSA:3.40.50.2300 2 138 6.4E-25 T 13-10-2018 Astex_0365 6b12e466dbd050fe5e242e542850c5e8 155 SMART SM00448 6 131 1.1E-19 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1156 b861c6a4824cec798bdcd1e2fe6d4aa2 298 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 3 277 1.0E-78 T 13-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 Astex_1156 b861c6a4824cec798bdcd1e2fe6d4aa2 298 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 8 273 2.2E-75 T 13-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 Astex_1156 b861c6a4824cec798bdcd1e2fe6d4aa2 298 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 143 155 - T 13-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 Astex_1156 b861c6a4824cec798bdcd1e2fe6d4aa2 298 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 5 279 19.236 T 13-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 Astex_2504 813df4519d3ff74d683bed4c1d9ad2e1 258 Gene3D G3DSA:3.40.50.720 1 256 9.0E-86 T 13-10-2018 Astex_2504 813df4519d3ff74d683bed4c1d9ad2e1 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 1.6E-40 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2504 813df4519d3ff74d683bed4c1d9ad2e1 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.6E-40 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2504 813df4519d3ff74d683bed4c1d9ad2e1 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 1.6E-40 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2504 813df4519d3ff74d683bed4c1d9ad2e1 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.6E-40 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2504 813df4519d3ff74d683bed4c1d9ad2e1 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.6E-40 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2504 813df4519d3ff74d683bed4c1d9ad2e1 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.6E-40 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2504 813df4519d3ff74d683bed4c1d9ad2e1 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 2.3E-11 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2504 813df4519d3ff74d683bed4c1d9ad2e1 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 2.3E-11 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2504 813df4519d3ff74d683bed4c1d9ad2e1 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 2.3E-11 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2504 813df4519d3ff74d683bed4c1d9ad2e1 258 SUPERFAMILY SSF51735 5 251 8.54E-82 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_2504 813df4519d3ff74d683bed4c1d9ad2e1 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 249 1.2E-69 T 13-10-2018 Astex_0608 69ea0bf93024129b7ae503fd111a6230 233 Gene3D G3DSA:1.10.10.10 119 227 3.1E-25 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_0608 69ea0bf93024129b7ae503fd111a6230 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 221 1.5E-19 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Astex_0608 69ea0bf93024129b7ae503fd111a6230 233 SUPERFAMILY SSF52172 1 174 7.26E-38 T 13-10-2018 IPR011006 CheY-like superfamily Astex_0608 69ea0bf93024129b7ae503fd111a6230 233 SMART SM00448 1 112 5.6E-38 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_0608 69ea0bf93024129b7ae503fd111a6230 233 Gene3D G3DSA:3.40.50.2300 1 118 4.5E-35 T 13-10-2018 Astex_0608 69ea0bf93024129b7ae503fd111a6230 233 SMART SM00862 145 221 3.9E-19 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Astex_0608 69ea0bf93024129b7ae503fd111a6230 233 Pfam PF00072 Response regulator receiver domain 3 112 1.7E-26 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_3561 67a4a57239d29346a02069b75965d8d9 279 Gene3D G3DSA:1.10.10.10 36 104 1.1E-15 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_3561 67a4a57239d29346a02069b75965d8d9 279 SUPERFAMILY SSF46785 38 107 3.16E-13 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_3561 67a4a57239d29346a02069b75965d8d9 279 Pfam PF09339 IclR helix-turn-helix domain 38 84 1.3E-11 T 13-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Astex_3561 67a4a57239d29346a02069b75965d8d9 279 Pfam PF01614 Bacterial transcriptional regulator 151 273 1.1E-17 T 13-10-2018 IPR014757 Transcription regulator IclR, C-terminal Astex_3561 67a4a57239d29346a02069b75965d8d9 279 Gene3D G3DSA:3.30.450.40 105 279 8.0E-44 T 13-10-2018 IPR029016 GAF-like domain superfamily Astex_3561 67a4a57239d29346a02069b75965d8d9 279 SUPERFAMILY SSF55781 99 277 2.94E-39 T 13-10-2018 Astex_3561 67a4a57239d29346a02069b75965d8d9 279 SMART SM00346 36 123 4.8E-16 T 13-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Astex_1994 6c953f0624aa93f77258f20311c75054 270 PRINTS PR00344 Bacterial sensor protein C-terminal signature 247 260 4.0E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1994 6c953f0624aa93f77258f20311c75054 270 PRINTS PR00344 Bacterial sensor protein C-terminal signature 189 203 4.0E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1994 6c953f0624aa93f77258f20311c75054 270 PRINTS PR00344 Bacterial sensor protein C-terminal signature 223 241 4.0E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_1994 6c953f0624aa93f77258f20311c75054 270 SMART SM00388 40 108 5.6E-13 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_1994 6c953f0624aa93f77258f20311c75054 270 SMART SM00387 152 263 3.2E-24 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_1994 6c953f0624aa93f77258f20311c75054 270 SUPERFAMILY SSF47384 33 107 6.67E-15 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Astex_1994 6c953f0624aa93f77258f20311c75054 270 Gene3D G3DSA:3.30.565.10 113 267 1.4E-28 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_1994 6c953f0624aa93f77258f20311c75054 270 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 153 261 5.2E-18 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_1994 6c953f0624aa93f77258f20311c75054 270 Pfam PF00512 His Kinase A (phospho-acceptor) domain 42 107 3.6E-12 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_1994 6c953f0624aa93f77258f20311c75054 270 SUPERFAMILY SSF55874 98 262 3.93E-34 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_1994 6c953f0624aa93f77258f20311c75054 270 Gene3D G3DSA:1.10.287.130 33 109 1.3E-15 T 13-10-2018 Astex_0970 c67dcc54e40d8d94db605acf4d6fc3a0 139 Gene3D G3DSA:3.90.1030.10 1 117 6.8E-47 T 13-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0970 c67dcc54e40d8d94db605acf4d6fc3a0 139 Pfam PF01196 Ribosomal protein L17 20 116 7.3E-35 T 13-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0970 c67dcc54e40d8d94db605acf4d6fc3a0 139 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 26.141 T 13-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0970 c67dcc54e40d8d94db605acf4d6fc3a0 139 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 13-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0970 c67dcc54e40d8d94db605acf4d6fc3a0 139 TIGRFAM TIGR00059 L17: ribosomal protein bL17 6 117 4.4E-41 T 13-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0970 c67dcc54e40d8d94db605acf4d6fc3a0 139 SUPERFAMILY SSF64263 1 119 5.76E-50 T 13-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_3647 96f551eafc921425a0bf980d572dbf1e 363 TIGRFAM TIGR03427 ABC_peri_uca: ABC transporter periplasmic binding protein, urea carboxylase region 37 363 1.2E-153 T 13-10-2018 IPR017793 ABC transporter, urea utilisation-associated, substrate-binding protein Astex_3647 96f551eafc921425a0bf980d572dbf1e 363 Gene3D G3DSA:3.40.190.10 57 282 4.6E-25 T 13-10-2018 Astex_3647 96f551eafc921425a0bf980d572dbf1e 363 Gene3D G3DSA:3.40.190.10 123 219 4.6E-25 T 13-10-2018 Astex_3647 96f551eafc921425a0bf980d572dbf1e 363 Pfam PF13379 NMT1-like family 47 263 1.1E-8 T 13-10-2018 Astex_3647 96f551eafc921425a0bf980d572dbf1e 363 SUPERFAMILY SSF53850 45 259 2.33E-32 T 13-10-2018 Astex_1166 0f0f96b27c685639b66b997bcb4ad976 221 SUPERFAMILY SSF55729 43 186 5.01E-35 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Astex_1166 0f0f96b27c685639b66b997bcb4ad976 221 Gene3D G3DSA:3.40.630.30 3 221 7.9E-60 T 13-10-2018 Astex_1166 0f0f96b27c685639b66b997bcb4ad976 221 Pfam PF13302 Acetyltransferase (GNAT) domain 61 162 1.4E-15 T 13-10-2018 IPR000182 GNAT domain Astex_2125 9c2e43827a346f614fdac474f73b93f3 889 SUPERFAMILY SSF49303 704 803 2.88E-24 T 13-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily Astex_2125 9c2e43827a346f614fdac474f73b93f3 889 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 99 163 8.4E-7 T 13-10-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 Astex_2125 9c2e43827a346f614fdac474f73b93f3 889 SUPERFAMILY SSF49785 45 233 6.66E-57 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_2125 9c2e43827a346f614fdac474f73b93f3 889 Gene3D G3DSA:2.60.40.10 800 888 3.6E-16 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_2125 9c2e43827a346f614fdac474f73b93f3 889 Gene3D G3DSA:3.20.20.80 341 701 3.1E-129 T 13-10-2018 Astex_2125 9c2e43827a346f614fdac474f73b93f3 889 SUPERFAMILY SSF49303 236 341 1.62E-18 T 13-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily Astex_2125 9c2e43827a346f614fdac474f73b93f3 889 Gene3D G3DSA:2.60.120.260 34 234 6.0E-67 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_2125 9c2e43827a346f614fdac474f73b93f3 889 SUPERFAMILY SSF49303 805 882 2.73E-13 T 13-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily Astex_2125 9c2e43827a346f614fdac474f73b93f3 889 Gene3D G3DSA:2.60.40.10 236 340 6.8E-16 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_2125 9c2e43827a346f614fdac474f73b93f3 889 SUPERFAMILY SSF51445 340 703 7.38E-110 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_2125 9c2e43827a346f614fdac474f73b93f3 889 Gene3D G3DSA:2.60.40.10 702 799 1.2E-16 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_2125 9c2e43827a346f614fdac474f73b93f3 889 Pfam PF00703 Glycosyl hydrolases family 2 237 342 5.4E-5 T 13-10-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 Astex_1775 a7b28c3387572a3e0e371c1bdf1d3fca 259 SUPERFAMILY SSF53613 1 257 4.05E-72 T 13-10-2018 IPR029056 Ribokinase-like Astex_1775 a7b28c3387572a3e0e371c1bdf1d3fca 259 Pfam PF08543 Phosphomethylpyrimidine kinase 11 253 2.4E-86 T 13-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 Astex_1775 a7b28c3387572a3e0e371c1bdf1d3fca 259 Gene3D G3DSA:3.40.1190.20 1 259 1.3E-89 T 13-10-2018 IPR029056 Ribokinase-like Astex_1775 a7b28c3387572a3e0e371c1bdf1d3fca 259 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 4 255 7.6E-85 T 13-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 Astex_0959 1a7ed7eccbb22d284a83a65d48b3314c 132 Pfam PF00410 Ribosomal protein S8 5 132 4.1E-44 T 13-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0959 1a7ed7eccbb22d284a83a65d48b3314c 132 Gene3D G3DSA:3.30.1490.10 75 132 4.8E-25 T 13-10-2018 Astex_0959 1a7ed7eccbb22d284a83a65d48b3314c 132 Gene3D G3DSA:3.30.1370.30 3 74 2.6E-20 T 13-10-2018 Astex_0959 1a7ed7eccbb22d284a83a65d48b3314c 132 SUPERFAMILY SSF56047 4 132 1.09E-41 T 13-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0959 1a7ed7eccbb22d284a83a65d48b3314c 132 ProSitePatterns PS00053 Ribosomal protein S8 signature. 102 119 - T 13-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0959 1a7ed7eccbb22d284a83a65d48b3314c 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 28.797 T 13-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0377 f6001f33b2c0e2976b4274d8d4ad0a10 370 SUPERFAMILY SSF52540 48 191 2.53E-15 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0377 f6001f33b2c0e2976b4274d8d4ad0a10 370 Gene3D G3DSA:3.40.50.300 10 188 3.2E-20 T 13-10-2018 Astex_0377 f6001f33b2c0e2976b4274d8d4ad0a10 370 Pfam PF03969 AFG1-like ATPase 5 367 2.2E-124 T 13-10-2018 IPR005654 ATPase, AFG1-like GO:0005524 Astex_2013 bf99fdd5ebda11f80f092e80df7d43b7 170 Gene3D G3DSA:1.10.8.640 30 110 9.3E-29 T 13-10-2018 IPR038297 CcmH/CycL/Ccl2/NrfF domain superfamily Astex_2013 bf99fdd5ebda11f80f092e80df7d43b7 170 Pfam PF03918 Cytochrome C biogenesis protein 19 162 2.8E-46 T 13-10-2018 IPR005616 CcmH/CycL/Ccl2/NrfF family Astex_2099 ad469672f371391957d1a0011b8f2ed8 157 Gene3D G3DSA:2.170.150.20 15 156 1.1E-54 T 13-10-2018 Astex_2099 ad469672f371391957d1a0011b8f2ed8 157 SUPERFAMILY SSF51316 21 142 1.4E-53 T 13-10-2018 IPR011057 Mss4-like superfamily Astex_2099 ad469672f371391957d1a0011b8f2ed8 157 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 14 140 35.816 T 13-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 Astex_2099 ad469672f371391957d1a0011b8f2ed8 157 Pfam PF01641 SelR domain 22 139 1.4E-47 T 13-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 Astex_2099 ad469672f371391957d1a0011b8f2ed8 157 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 21 140 1.1E-49 T 13-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 Astex_2217 eb08f05e1c6e3c135a31ea6ad95e0847 307 SUPERFAMILY SSF53448 6 257 3.37E-33 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_2217 eb08f05e1c6e3c135a31ea6ad95e0847 307 Gene3D G3DSA:3.90.550.10 5 262 5.8E-39 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_2217 eb08f05e1c6e3c135a31ea6ad95e0847 307 Pfam PF01501 Glycosyl transferase family 8 5 241 5.6E-24 T 13-10-2018 IPR002495 Glycosyl transferase, family 8 GO:0016757 Astex_1610 25f8d66ff13022654c25f1aab0b9060c 343 SUPERFAMILY SSF48576 24 342 2.88E-92 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily Astex_1610 25f8d66ff13022654c25f1aab0b9060c 343 Pfam PF00348 Polyprenyl synthetase 53 293 2.0E-70 T 13-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 Astex_1610 25f8d66ff13022654c25f1aab0b9060c 343 Gene3D G3DSA:1.10.600.10 18 342 3.4E-112 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily Astex_1610 25f8d66ff13022654c25f1aab0b9060c 343 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 101 115 - T 13-10-2018 IPR033749 Polyprenyl synthetase, conserved site Astex_1847 6035ef2de6fdb7b4580a27ba849bb1e1 150 Gene3D G3DSA:2.40.330.20 1 148 9.9E-28 T 13-10-2018 IPR038619 MraZ superfamily Astex_1847 6035ef2de6fdb7b4580a27ba849bb1e1 150 Pfam PF02381 MraZ protein, putative antitoxin-like 83 141 9.2E-10 T 13-10-2018 IPR020603 MraZ domain Astex_1847 6035ef2de6fdb7b4580a27ba849bb1e1 150 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 150 25.721 T 13-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 Astex_1847 6035ef2de6fdb7b4580a27ba849bb1e1 150 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 148 9.0E-12 T 13-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 Astex_1847 6035ef2de6fdb7b4580a27ba849bb1e1 150 SUPERFAMILY SSF89447 2 140 3.4E-27 T 13-10-2018 IPR037914 SpoVT-AbrB domain superfamily Astex_1769 62a269c474893a28c4dba6f82a091b63 304 Gene3D G3DSA:2.40.70.10 25 151 1.0E-17 T 13-10-2018 IPR021109 Aspartic peptidase domain superfamily Astex_1769 62a269c474893a28c4dba6f82a091b63 304 Gene3D G3DSA:2.40.70.10 173 301 5.7E-11 T 13-10-2018 IPR021109 Aspartic peptidase domain superfamily Astex_1769 62a269c474893a28c4dba6f82a091b63 304 ProSitePatterns PS00141 Eukaryotic and viral aspartyl proteases active site. 56 67 - T 13-10-2018 IPR001969 Aspartic peptidase, active site GO:0004190|GO:0006508 Astex_1769 62a269c474893a28c4dba6f82a091b63 304 Pfam PF13650 Aspartyl protease 44 133 9.0E-14 T 13-10-2018 Astex_1769 62a269c474893a28c4dba6f82a091b63 304 Pfam PF13650 Aspartyl protease 183 283 4.6E-11 T 13-10-2018 Astex_1769 62a269c474893a28c4dba6f82a091b63 304 SUPERFAMILY SSF50630 34 143 4.93E-11 T 13-10-2018 IPR021109 Aspartic peptidase domain superfamily Astex_2699 5aeaf3f706f005144dd8ee5d20d5ff25 278 PIRSF PIRSF016184 1 276 1.2E-66 T 13-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 Astex_2699 5aeaf3f706f005144dd8ee5d20d5ff25 278 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 5 256 2.0E-44 T 13-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 Astex_2699 5aeaf3f706f005144dd8ee5d20d5ff25 278 SUPERFAMILY SSF54506 5 275 1.92E-63 T 13-10-2018 Astex_2699 5aeaf3f706f005144dd8ee5d20d5ff25 278 Gene3D G3DSA:3.10.310.10 9 123 3.1E-72 T 13-10-2018 Astex_2699 5aeaf3f706f005144dd8ee5d20d5ff25 278 Pfam PF02567 Phenazine biosynthesis-like protein 9 267 9.6E-47 T 13-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 Astex_2699 5aeaf3f706f005144dd8ee5d20d5ff25 278 Gene3D G3DSA:3.10.310.10 124 270 3.1E-72 T 13-10-2018 Astex_0560 735933fe803eaf6353eee8e0565e007d 719 Pfam PF07715 TonB-dependent Receptor Plug Domain 73 155 4.8E-9 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_0560 735933fe803eaf6353eee8e0565e007d 719 SUPERFAMILY SSF56935 49 676 6.96E-62 T 13-10-2018 Astex_0560 735933fe803eaf6353eee8e0565e007d 719 Gene3D G3DSA:2.40.170.20 219 713 2.4E-25 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_0560 735933fe803eaf6353eee8e0565e007d 719 Gene3D G3DSA:2.170.130.10 55 164 6.5E-13 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_0560 735933fe803eaf6353eee8e0565e007d 719 Pfam PF14905 Outer membrane protein beta-barrel family 310 684 4.1E-55 T 13-10-2018 Astex_2033 5d3d0cfa7ab958253ee2d0a394e5677b 225 Pfam PF00188 Cysteine-rich secretory protein family 90 216 4.0E-20 T 13-10-2018 IPR014044 CAP domain Astex_2033 5d3d0cfa7ab958253ee2d0a394e5677b 225 Gene3D G3DSA:3.40.33.10 47 217 3.5E-44 T 13-10-2018 IPR035940 CAP superfamily Astex_2033 5d3d0cfa7ab958253ee2d0a394e5677b 225 SUPERFAMILY SSF55797 84 217 5.36E-20 T 13-10-2018 IPR035940 CAP superfamily Astex_3415 908aa133cc74cb80c9b8882bea05f89b 436 Gene3D G3DSA:1.20.1250.20 225 431 7.7E-28 T 13-10-2018 Astex_3415 908aa133cc74cb80c9b8882bea05f89b 436 Gene3D G3DSA:1.20.1250.20 11 207 3.3E-47 T 13-10-2018 Astex_3415 908aa133cc74cb80c9b8882bea05f89b 436 PIRSF PIRSF002808 8 434 1.7E-33 T 13-10-2018 IPR000849 Sugar phosphate transporter GO:0016021|GO:0022857|GO:0055085 Astex_3415 908aa133cc74cb80c9b8882bea05f89b 436 SUPERFAMILY SSF103473 11 432 2.09E-79 T 13-10-2018 IPR036259 MFS transporter superfamily Astex_3415 908aa133cc74cb80c9b8882bea05f89b 436 Pfam PF07690 Major Facilitator Superfamily 24 356 1.6E-48 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Astex_3642 12b722f8fcd6b7a39144bf25c3698f74 586 Gene3D G3DSA:3.90.1300.10 40 436 4.8E-145 T 13-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Astex_3642 12b722f8fcd6b7a39144bf25c3698f74 586 Gene3D G3DSA:1.20.58.1700 289 362 4.8E-145 T 13-10-2018 Astex_3642 12b722f8fcd6b7a39144bf25c3698f74 586 Gene3D G3DSA:3.10.490.10 455 586 2.1E-48 T 13-10-2018 Astex_3642 12b722f8fcd6b7a39144bf25c3698f74 586 Pfam PF01425 Amidase 31 433 2.6E-79 T 13-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Astex_3642 12b722f8fcd6b7a39144bf25c3698f74 586 SUPERFAMILY SSF75304 4 439 2.22E-105 T 13-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Astex_3642 12b722f8fcd6b7a39144bf25c3698f74 586 TIGRFAM TIGR02713 allophanate_hyd: allophanate hydrolase 40 583 5.1E-221 T 13-10-2018 IPR014085 Allophanate hydrolase KEGG: 00220+3.5.1.54|KEGG: 00791+3.5.1.54|MetaCyc: PWY-5169|MetaCyc: PWY-5703 Astex_1941 51bf7fe947b03c009fb863e154b23868 439 PIRSF PIRSF005353 1 438 2.0E-175 T 13-10-2018 IPR026033 Purine permease PbuG-like Astex_1941 51bf7fe947b03c009fb863e154b23868 439 Pfam PF00860 Permease family 20 395 5.3E-47 T 13-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 Astex_3667 3874736a4e4fcf5a58da92c7e8cd7426 116 SUPERFAMILY SSF51182 25 109 1.59E-16 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily Astex_3667 3874736a4e4fcf5a58da92c7e8cd7426 116 Gene3D G3DSA:2.60.120.10 5 108 2.9E-15 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Astex_3667 3874736a4e4fcf5a58da92c7e8cd7426 116 Pfam PF07883 Cupin domain 44 107 2.2E-8 T 13-10-2018 IPR013096 Cupin 2, conserved barrel Astex_3633 ea6676b72f50c00e1c7e7e69151cd157 338 SUPERFAMILY SSF75005 27 322 3.0E-57 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Astex_3633 ea6676b72f50c00e1c7e7e69151cd157 338 Pfam PF04616 Glycosyl hydrolases family 43 42 322 6.6E-42 T 13-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 Astex_3633 ea6676b72f50c00e1c7e7e69151cd157 338 Gene3D G3DSA:2.115.10.20 35 337 9.4E-89 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Astex_1563 baf7e7198b07ce234d8c6af5470391d0 370 PIRSF PIRSF006487 1 370 1.9E-77 T 13-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 Astex_1563 baf7e7198b07ce234d8c6af5470391d0 370 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 266 355 7.0E-19 T 13-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 Astex_1563 baf7e7198b07ce234d8c6af5470391d0 370 Gene3D G3DSA:2.40.30.110 279 356 6.8E-27 T 13-10-2018 Astex_1563 baf7e7198b07ce234d8c6af5470391d0 370 Pfam PF01571 Aminomethyltransferase folate-binding domain 11 255 7.1E-84 T 13-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain Astex_1563 baf7e7198b07ce234d8c6af5470391d0 370 Gene3D G3DSA:3.30.1360.120 7 233 5.3E-82 T 13-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 Astex_1563 baf7e7198b07ce234d8c6af5470391d0 370 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 6 361 1.1E-109 T 13-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 Astex_1563 baf7e7198b07ce234d8c6af5470391d0 370 Gene3D G3DSA:4.10.1250.10 234 277 1.3E-9 T 13-10-2018 Astex_1563 baf7e7198b07ce234d8c6af5470391d0 370 SUPERFAMILY SSF103025 6 261 5.81E-81 T 13-10-2018 Astex_1563 baf7e7198b07ce234d8c6af5470391d0 370 Gene3D G3DSA:3.30.70.1400 56 140 5.3E-82 T 13-10-2018 Astex_1563 baf7e7198b07ce234d8c6af5470391d0 370 SUPERFAMILY SSF101790 277 366 8.18E-25 T 13-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal Astex_2392 3e4a21928d2eb03df18a34736b9c05cf 304 Gene3D G3DSA:3.40.190.10 170 265 5.5E-56 T 13-10-2018 Astex_2392 3e4a21928d2eb03df18a34736b9c05cf 304 Gene3D G3DSA:1.10.10.10 1 88 6.4E-30 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_2392 3e4a21928d2eb03df18a34736b9c05cf 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 2.1E-18 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_2392 3e4a21928d2eb03df18a34736b9c05cf 304 Pfam PF03466 LysR substrate binding domain 98 291 1.6E-22 T 13-10-2018 IPR005119 LysR, substrate-binding Astex_2392 3e4a21928d2eb03df18a34736b9c05cf 304 SUPERFAMILY SSF46785 5 86 1.86E-20 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_2392 3e4a21928d2eb03df18a34736b9c05cf 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 1.4E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_2392 3e4a21928d2eb03df18a34736b9c05cf 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 1.4E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_2392 3e4a21928d2eb03df18a34736b9c05cf 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 1.4E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_2392 3e4a21928d2eb03df18a34736b9c05cf 304 Gene3D G3DSA:3.40.190.10 90 288 5.5E-56 T 13-10-2018 Astex_2392 3e4a21928d2eb03df18a34736b9c05cf 304 SUPERFAMILY SSF53850 90 292 2.48E-37 T 13-10-2018 Astex_3570 1316faeed963e384fe9a9f3ff9d73e28 360 SUPERFAMILY SSF110849 71 173 1.15E-11 T 13-10-2018 IPR036086 ParB/Sulfiredoxin superfamily Astex_3570 1316faeed963e384fe9a9f3ff9d73e28 360 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 78 233 7.5E-25 T 13-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 Astex_3570 1316faeed963e384fe9a9f3ff9d73e28 360 SUPERFAMILY SSF109709 164 236 2.62E-10 T 13-10-2018 Astex_3570 1316faeed963e384fe9a9f3ff9d73e28 360 Gene3D G3DSA:1.10.10.2830 175 298 1.0E-20 T 13-10-2018 Astex_3570 1316faeed963e384fe9a9f3ff9d73e28 360 Pfam PF02195 ParB-like nuclease domain 72 170 9.0E-12 T 13-10-2018 IPR003115 ParB/Sulfiredoxin Astex_3570 1316faeed963e384fe9a9f3ff9d73e28 360 SMART SM00470 70 171 6.0E-9 T 13-10-2018 IPR003115 ParB/Sulfiredoxin Astex_1102 0c504e4561aa9ed96049f294b0b28c90 271 Gene3D G3DSA:1.20.120.350 7 119 2.7E-30 T 13-10-2018 IPR027359 Voltage-dependent channel domain superfamily Astex_1102 0c504e4561aa9ed96049f294b0b28c90 271 Pfam PF00520 Ion transport protein 16 231 2.3E-40 T 13-10-2018 IPR005821 Ion transport domain GO:0005216|GO:0006811|GO:0016020|GO:0055085 Astex_1102 0c504e4561aa9ed96049f294b0b28c90 271 Gene3D G3DSA:1.10.287.70 130 225 5.8E-28 T 13-10-2018 Astex_1102 0c504e4561aa9ed96049f294b0b28c90 271 SUPERFAMILY SSF81324 16 228 1.31E-32 T 13-10-2018 Astex_0168 867db9eb234997dde27c699412233f58 156 Gene3D G3DSA:3.40.390.30 5 156 1.5E-45 T 13-10-2018 IPR023091 Metalloprotease catalytic domain superfamily, predicted GO:0004222 Astex_0168 867db9eb234997dde27c699412233f58 156 SUPERFAMILY SSF55486 21 153 1.12E-41 T 13-10-2018 Astex_0168 867db9eb234997dde27c699412233f58 156 Pfam PF02130 Uncharacterized protein family UPF0054 25 146 1.7E-35 T 13-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 Astex_0168 867db9eb234997dde27c699412233f58 156 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 117 127 - T 13-10-2018 IPR020549 Endoribonuclease YbeY, conserved site Astex_0168 867db9eb234997dde27c699412233f58 156 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 7 151 22.563 T 13-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 Astex_0168 867db9eb234997dde27c699412233f58 156 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 46 147 1.5E-32 T 13-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 Astex_1965 59d5791170ce33603f8d5125190cca39 984 SUPERFAMILY SSF81301 48 311 8.39E-59 T 13-10-2018 Astex_1965 59d5791170ce33603f8d5125190cca39 984 Hamap MF_00802 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme [glnE]. 47 967 16.578 T 13-10-2018 IPR023057 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme GO:0008882 Astex_1965 59d5791170ce33603f8d5125190cca39 984 Gene3D G3DSA:3.30.460.100 585 825 3.6E-59 T 13-10-2018 Astex_1965 59d5791170ce33603f8d5125190cca39 984 Gene3D G3DSA:3.30.460.100 59 305 2.4E-56 T 13-10-2018 Astex_1965 59d5791170ce33603f8d5125190cca39 984 SUPERFAMILY SSF81593 839 980 7.45E-25 T 13-10-2018 Astex_1965 59d5791170ce33603f8d5125190cca39 984 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 52 300 1.3E-61 T 13-10-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 Astex_1965 59d5791170ce33603f8d5125190cca39 984 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 576 814 3.4E-62 T 13-10-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 Astex_1965 59d5791170ce33603f8d5125190cca39 984 Gene3D G3DSA:1.20.120.330 310 468 1.7E-47 T 13-10-2018 Astex_1965 59d5791170ce33603f8d5125190cca39 984 Gene3D G3DSA:1.20.120.330 835 983 9.4E-22 T 13-10-2018 Astex_1965 59d5791170ce33603f8d5125190cca39 984 Gene3D G3DSA:1.20.120.1510 476 582 3.4E-5 T 13-10-2018 Astex_1965 59d5791170ce33603f8d5125190cca39 984 SUPERFAMILY SSF81301 550 824 1.05E-60 T 13-10-2018 Astex_1965 59d5791170ce33603f8d5125190cca39 984 Pfam PF08335 GlnD PII-uridylyltransferase 845 979 1.0E-7 T 13-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 Astex_1965 59d5791170ce33603f8d5125190cca39 984 Pfam PF08335 GlnD PII-uridylyltransferase 323 464 6.8E-37 T 13-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 Astex_1965 59d5791170ce33603f8d5125190cca39 984 SUPERFAMILY SSF81593 313 464 1.88E-38 T 13-10-2018 Astex_0380 f7518f912b397d0cad3978d0025546bc 342 SUPERFAMILY SSF55347 129 319 1.25E-75 T 13-10-2018 Astex_0380 f7518f912b397d0cad3978d0025546bc 342 SUPERFAMILY SSF51735 3 157 2.53E-50 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_0380 f7518f912b397d0cad3978d0025546bc 342 Gene3D G3DSA:3.40.50.720 5 330 4.8E-137 T 13-10-2018 Astex_0380 f7518f912b397d0cad3978d0025546bc 342 PIRSF PIRSF000148 2 337 2.6E-125 T 13-10-2018 Astex_0380 f7518f912b397d0cad3978d0025546bc 342 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 2 332 35.513 T 13-10-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 Astex_0380 f7518f912b397d0cad3978d0025546bc 342 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 4 116 9.1E-32 T 13-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 Astex_0380 f7518f912b397d0cad3978d0025546bc 342 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 4 331 2.4E-141 T 13-10-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 Astex_0380 f7518f912b397d0cad3978d0025546bc 342 SMART SM00859 4 119 2.1E-36 T 13-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 Astex_0380 f7518f912b397d0cad3978d0025546bc 342 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 139 318 1.9E-53 T 13-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Astex_0380 f7518f912b397d0cad3978d0025546bc 342 Gene3D G3DSA:3.30.360.10 128 315 4.8E-137 T 13-10-2018 Astex_3404 0bec18295a7ce01f7453f460d4e98c81 766 Gene3D G3DSA:2.60.40.10 637 750 4.9E-29 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_3404 0bec18295a7ce01f7453f460d4e98c81 766 PRINTS PR00133 Glycosyl hydrolase family 3 signature 286 304 1.5E-29 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_3404 0bec18295a7ce01f7453f460d4e98c81 766 PRINTS PR00133 Glycosyl hydrolase family 3 signature 216 232 1.5E-29 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_3404 0bec18295a7ce01f7453f460d4e98c81 766 PRINTS PR00133 Glycosyl hydrolase family 3 signature 110 126 1.5E-29 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_3404 0bec18295a7ce01f7453f460d4e98c81 766 PRINTS PR00133 Glycosyl hydrolase family 3 signature 139 158 1.5E-29 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_3404 0bec18295a7ce01f7453f460d4e98c81 766 PRINTS PR00133 Glycosyl hydrolase family 3 signature 185 201 1.5E-29 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_3404 0bec18295a7ce01f7453f460d4e98c81 766 SMART SM01217 670 740 3.3E-21 T 13-10-2018 IPR026891 Fibronectin type III-like domain Astex_3404 0bec18295a7ce01f7453f460d4e98c81 766 Gene3D G3DSA:3.40.50.1700 378 636 1.5E-67 T 13-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 Astex_3404 0bec18295a7ce01f7453f460d4e98c81 766 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 286 303 - T 13-10-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 Astex_3404 0bec18295a7ce01f7453f460d4e98c81 766 SUPERFAMILY SSF52279 392 640 9.55E-48 T 13-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 Astex_3404 0bec18295a7ce01f7453f460d4e98c81 766 Pfam PF14310 Fibronectin type III-like domain 670 738 4.9E-19 T 13-10-2018 IPR026891 Fibronectin type III-like domain Astex_3404 0bec18295a7ce01f7453f460d4e98c81 766 SUPERFAMILY SSF51445 40 369 6.21E-87 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_3404 0bec18295a7ce01f7453f460d4e98c81 766 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 392 637 1.2E-52 T 13-10-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 Astex_3404 0bec18295a7ce01f7453f460d4e98c81 766 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 110 355 5.1E-43 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_3404 0bec18295a7ce01f7453f460d4e98c81 766 Gene3D G3DSA:3.20.20.300 31 363 3.4E-97 T 13-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 Astex_3291 786e3ebf3ec33a12b1b101f10c39ba2a 129 Gene3D G3DSA:3.40.50.2300 3 125 1.3E-22 T 13-10-2018 Astex_3291 786e3ebf3ec33a12b1b101f10c39ba2a 129 SUPERFAMILY SSF52172 8 123 4.13E-25 T 13-10-2018 IPR011006 CheY-like superfamily Astex_3291 786e3ebf3ec33a12b1b101f10c39ba2a 129 SMART SM00448 6 122 6.5E-16 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_3291 786e3ebf3ec33a12b1b101f10c39ba2a 129 Pfam PF00072 Response regulator receiver domain 8 122 2.6E-16 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_0847 6f3fc8c71d1e83d3af6d70705da7125b 358 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 294 314 - T 13-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 Astex_0847 6f3fc8c71d1e83d3af6d70705da7125b 358 Gene3D G3DSA:3.20.20.70 4 358 2.1E-123 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_0847 6f3fc8c71d1e83d3af6d70705da7125b 358 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 81 100 - T 13-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 Astex_0847 6f3fc8c71d1e83d3af6d70705da7125b 358 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 4 356 7.8E-106 T 13-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 Astex_0847 6f3fc8c71d1e83d3af6d70705da7125b 358 SUPERFAMILY SSF51395 7 356 2.11E-94 T 13-10-2018 Astex_0847 6f3fc8c71d1e83d3af6d70705da7125b 358 Pfam PF01180 Dihydroorotate dehydrogenase 55 342 1.2E-79 T 13-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 Astex_1608 1ed3aaf11453099d4a5c67812df3fa4a 157 Gene3D G3DSA:3.90.79.10 12 150 1.8E-22 T 13-10-2018 Astex_1608 1ed3aaf11453099d4a5c67812df3fa4a 157 ProSitePatterns PS00893 Nudix box signature. 57 78 - T 13-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 Astex_1608 1ed3aaf11453099d4a5c67812df3fa4a 157 SUPERFAMILY SSF55811 22 149 1.08E-21 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 Astex_1608 1ed3aaf11453099d4a5c67812df3fa4a 157 Pfam PF00293 NUDIX domain 29 136 5.3E-16 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 Astex_2134 a7771b1b34bf271a9b0731c05578436f 129 Gene3D G3DSA:1.10.10.10 38 122 5.6E-20 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_2134 a7771b1b34bf271a9b0731c05578436f 129 Pfam PF09339 IclR helix-turn-helix domain 56 102 1.8E-14 T 13-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Astex_2134 a7771b1b34bf271a9b0731c05578436f 129 SMART SM00346 54 129 1.3E-13 T 13-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Astex_2134 a7771b1b34bf271a9b0731c05578436f 129 SUPERFAMILY SSF46785 55 128 1.59E-12 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_3417 19f9fae0843eb02c700728d038df1958 249 SUPERFAMILY SSF55781 73 248 2.68E-27 T 13-10-2018 Astex_3417 19f9fae0843eb02c700728d038df1958 249 SUPERFAMILY SSF46785 10 78 4.69E-14 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_3417 19f9fae0843eb02c700728d038df1958 249 Gene3D G3DSA:3.30.450.40 77 249 2.7E-27 T 13-10-2018 IPR029016 GAF-like domain superfamily Astex_3417 19f9fae0843eb02c700728d038df1958 249 SMART SM00346 8 97 3.7E-18 T 13-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Astex_3417 19f9fae0843eb02c700728d038df1958 249 Pfam PF01614 Bacterial transcriptional regulator 128 246 2.9E-9 T 13-10-2018 IPR014757 Transcription regulator IclR, C-terminal Astex_3417 19f9fae0843eb02c700728d038df1958 249 Pfam PF09339 IclR helix-turn-helix domain 10 60 9.2E-11 T 13-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 Astex_3417 19f9fae0843eb02c700728d038df1958 249 Gene3D G3DSA:1.10.10.10 2 76 3.3E-15 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1071 dc54620641d2c358350ee4b9f1a58e54 152 PRINTS PR00502 NUDIX hydrolase family signature 43 57 2.9E-7 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 Astex_1071 dc54620641d2c358350ee4b9f1a58e54 152 PRINTS PR00502 NUDIX hydrolase family signature 57 72 2.9E-7 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 Astex_1071 dc54620641d2c358350ee4b9f1a58e54 152 Pfam PF00293 NUDIX domain 21 133 1.7E-15 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 Astex_1071 dc54620641d2c358350ee4b9f1a58e54 152 SUPERFAMILY SSF55811 9 145 5.69E-22 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 Astex_1071 dc54620641d2c358350ee4b9f1a58e54 152 Gene3D G3DSA:3.90.79.10 6 146 4.9E-26 T 13-10-2018 Astex_0061 08bcfa9f4db4b7d7b146ee7db4ee7d7e 413 SUPERFAMILY SSF52507 18 195 4.06E-58 T 13-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 Astex_0061 08bcfa9f4db4b7d7b146ee7db4ee7d7e 413 SUPERFAMILY SSF102645 200 412 2.09E-66 T 13-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 Astex_0061 08bcfa9f4db4b7d7b146ee7db4ee7d7e 413 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 22 408 6.1E-122 T 13-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 Astex_0061 08bcfa9f4db4b7d7b146ee7db4ee7d7e 413 Gene3D G3DSA:3.40.50.10300 199 413 1.7E-68 T 13-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 Astex_0061 08bcfa9f4db4b7d7b146ee7db4ee7d7e 413 Pfam PF02441 Flavoprotein 22 193 3.2E-43 T 13-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 Astex_0061 08bcfa9f4db4b7d7b146ee7db4ee7d7e 413 Gene3D G3DSA:3.40.50.1950 15 198 6.4E-56 T 13-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 Astex_0061 08bcfa9f4db4b7d7b146ee7db4ee7d7e 413 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 202 384 2.8E-65 T 13-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 Astex_1613 29306790b7fcae147864d90a4ac08e24 149 Gene3D G3DSA:1.10.10.10 2 142 3.0E-35 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1613 29306790b7fcae147864d90a4ac08e24 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 5.3E-9 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Astex_1613 29306790b7fcae147864d90a4ac08e24 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 51 67 5.3E-9 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Astex_1613 29306790b7fcae147864d90a4ac08e24 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 5.3E-9 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Astex_1613 29306790b7fcae147864d90a4ac08e24 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 137 5.3E-9 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Astex_1613 29306790b7fcae147864d90a4ac08e24 149 SUPERFAMILY SSF46785 4 139 8.14E-32 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_1613 29306790b7fcae147864d90a4ac08e24 149 SMART SM00347 27 127 1.2E-20 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Astex_1613 29306790b7fcae147864d90a4ac08e24 149 Pfam PF01047 MarR family 35 91 1.8E-12 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Astex_1613 29306790b7fcae147864d90a4ac08e24 149 ProSitePatterns PS01117 MarR-type HTH domain signature. 66 100 - T 13-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site Astex_2189 8d65c88d7751d9dc44ca5a6e116b5fc9 484 Pfam PF13440 Polysaccharide biosynthesis protein 31 318 1.4E-37 T 13-10-2018 Astex_3208 9313f59726eda36f3ae2b900b76b3d81 535 Gene3D G3DSA:2.115.10.20 53 336 6.5E-70 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Astex_3208 9313f59726eda36f3ae2b900b76b3d81 535 Pfam PF04616 Glycosyl hydrolases family 43 54 326 8.9E-85 T 13-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 Astex_3208 9313f59726eda36f3ae2b900b76b3d81 535 SUPERFAMILY SSF49899 351 521 1.23E-20 T 13-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily Astex_3208 9313f59726eda36f3ae2b900b76b3d81 535 Gene3D G3DSA:2.60.120.200 352 533 6.5E-18 T 13-10-2018 Astex_3208 9313f59726eda36f3ae2b900b76b3d81 535 SUPERFAMILY SSF75005 54 331 1.01E-72 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Astex_3691 daffc001ec94bc16b7228984dd15d2f6 307 Gene3D G3DSA:2.60.120.1440 95 219 1.1E-24 T 13-10-2018 Astex_3691 daffc001ec94bc16b7228984dd15d2f6 307 Gene3D G3DSA:3.55.50.30 230 304 4.4E-7 T 13-10-2018 Astex_3691 daffc001ec94bc16b7228984dd15d2f6 307 Pfam PF04773 FecR protein 101 189 5.3E-19 T 13-10-2018 IPR006860 FecR protein Astex_3691 daffc001ec94bc16b7228984dd15d2f6 307 PIRSF PIRSF018266 8 306 8.2E-61 T 13-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component Astex_0411 df7f6e684a2628588809ecddaa953ea6 570 Gene3D G3DSA:2.40.10.10 40 140 7.0E-11 T 13-10-2018 Astex_0411 df7f6e684a2628588809ecddaa953ea6 570 PRINTS PR00834 HtrA/DegQ protease family signature 200 217 1.9E-7 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Astex_0411 df7f6e684a2628588809ecddaa953ea6 570 PRINTS PR00834 HtrA/DegQ protease family signature 222 239 1.9E-7 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Astex_0411 df7f6e684a2628588809ecddaa953ea6 570 PRINTS PR00834 HtrA/DegQ protease family signature 84 96 1.9E-7 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 Astex_0411 df7f6e684a2628588809ecddaa953ea6 570 Pfam PF13365 Trypsin-like peptidase domain 76 229 1.2E-20 T 13-10-2018 Astex_0411 df7f6e684a2628588809ecddaa953ea6 570 SUPERFAMILY SSF50494 18 264 3.15E-31 T 13-10-2018 IPR009003 Peptidase S1, PA clan Astex_0411 df7f6e684a2628588809ecddaa953ea6 570 Gene3D G3DSA:2.40.10.10 141 263 2.2E-15 T 13-10-2018 Astex_3146 4576acf0334032db45d6a153d4ab3229 222 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 185 1.7E-29 T 13-10-2018 Astex_3146 4576acf0334032db45d6a153d4ab3229 222 Gene3D G3DSA:1.10.150.240 16 83 3.8E-49 T 13-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 Astex_3146 4576acf0334032db45d6a153d4ab3229 222 Gene3D G3DSA:3.40.50.1000 5 204 3.8E-49 T 13-10-2018 IPR023214 HAD superfamily Astex_3146 4576acf0334032db45d6a153d4ab3229 222 SUPERFAMILY SSF56784 1 216 2.27E-57 T 13-10-2018 IPR036412 HAD-like superfamily Astex_3146 4576acf0334032db45d6a153d4ab3229 222 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 86 185 5.3E-8 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Astex_3146 4576acf0334032db45d6a153d4ab3229 222 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 91 179 2.2E-10 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Astex_3855 a46b017e8e82f036371e4b28128a490d 313 SUPERFAMILY SSF161111 24 221 8.89E-59 T 13-10-2018 IPR027469 Cation efflux transmembrane domain superfamily Astex_3855 a46b017e8e82f036371e4b28128a490d 313 Gene3D G3DSA:1.20.1510.10 25 220 2.9E-46 T 13-10-2018 IPR027469 Cation efflux transmembrane domain superfamily Astex_3855 a46b017e8e82f036371e4b28128a490d 313 Pfam PF01545 Cation efflux family 29 220 4.1E-50 T 13-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 Astex_3855 a46b017e8e82f036371e4b28128a490d 313 SUPERFAMILY SSF160240 228 296 4.32E-7 T 13-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 Astex_3855 a46b017e8e82f036371e4b28128a490d 313 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 25 298 1.8E-89 T 13-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 Astex_2819 2d0bc224c258305d5a6c76818b52a109 261 Gene3D G3DSA:3.30.420.40 1 88 5.4E-29 T 13-10-2018 Astex_2819 2d0bc224c258305d5a6c76818b52a109 261 Pfam PF03309 Type III pantothenate kinase 2 205 8.4E-65 T 13-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 Astex_2819 2d0bc224c258305d5a6c76818b52a109 261 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 2 247 1.7E-64 T 13-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 Astex_2819 2d0bc224c258305d5a6c76818b52a109 261 SUPERFAMILY SSF53067 1 122 4.1E-32 T 13-10-2018 Astex_2819 2d0bc224c258305d5a6c76818b52a109 261 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 254 33.705 T 13-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 Astex_2819 2d0bc224c258305d5a6c76818b52a109 261 Gene3D G3DSA:3.30.420.40 89 261 5.9E-58 T 13-10-2018 Astex_2819 2d0bc224c258305d5a6c76818b52a109 261 SUPERFAMILY SSF53067 123 252 1.14E-37 T 13-10-2018 Astex_3690 1aaa35cba44a3b757bb96bf6ba6acb63 392 Pfam PF00107 Zinc-binding dehydrogenase 196 269 5.0E-11 T 13-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Astex_3690 1aaa35cba44a3b757bb96bf6ba6acb63 392 SUPERFAMILY SSF51735 163 354 3.94E-63 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_3690 1aaa35cba44a3b757bb96bf6ba6acb63 392 Gene3D G3DSA:3.40.50.720 177 343 4.0E-134 T 13-10-2018 Astex_3690 1aaa35cba44a3b757bb96bf6ba6acb63 392 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 13-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 Astex_3690 1aaa35cba44a3b757bb96bf6ba6acb63 392 SUPERFAMILY SSF50129 1 203 7.64E-63 T 13-10-2018 IPR011032 GroES-like superfamily Astex_3690 1aaa35cba44a3b757bb96bf6ba6acb63 392 Gene3D G3DSA:3.90.180.10 10 378 4.0E-134 T 13-10-2018 Astex_3690 1aaa35cba44a3b757bb96bf6ba6acb63 392 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 148 1.6E-28 T 13-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Astex_3690 1aaa35cba44a3b757bb96bf6ba6acb63 392 Pfam PF13823 Alcohol dehydrogenase GroES-associated 1 22 3.2E-10 T 13-10-2018 IPR027399 Alcohol dehydrogenase GroES-associated Astex_1803 c8bdb77208504f41401d633520b5c648 115 Gene3D G3DSA:1.10.238.10 14 67 1.5E-6 T 13-10-2018 Astex_1803 c8bdb77208504f41401d633520b5c648 115 ProSitePatterns PS00018 EF-hand calcium-binding domain. 76 88 - T 13-10-2018 IPR018247 EF-Hand 1, calcium-binding site Astex_1803 c8bdb77208504f41401d633520b5c648 115 Pfam PF00036 EF hand 70 94 1.1E-6 T 13-10-2018 IPR002048 EF-hand domain GO:0005509 Astex_1803 c8bdb77208504f41401d633520b5c648 115 Gene3D G3DSA:1.10.238.10 68 97 1.9E-9 T 13-10-2018 Astex_1803 c8bdb77208504f41401d633520b5c648 115 SMART SM00054 72 95 1.9 T 13-10-2018 IPR002048 EF-hand domain GO:0005509 Astex_1803 c8bdb77208504f41401d633520b5c648 115 SMART SM00054 43 71 3.4 T 13-10-2018 IPR002048 EF-hand domain GO:0005509 Astex_1803 c8bdb77208504f41401d633520b5c648 115 SUPERFAMILY SSF47473 45 94 3.38E-13 T 13-10-2018 IPR011992 EF-hand domain pair Astex_1803 c8bdb77208504f41401d633520b5c648 115 Pfam PF13202 EF hand 48 65 7.4E-6 T 13-10-2018 IPR002048 EF-hand domain GO:0005509 Astex_1452 75215626a33f147d6c33d319d21359c5 466 SMART SM00729 61 282 6.9E-51 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Astex_1452 75215626a33f147d6c33d319d21359c5 466 Gene3D G3DSA:3.80.30.20 11 373 3.0E-104 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe Astex_1452 75215626a33f147d6c33d319d21359c5 466 TIGRFAM TIGR00538 hemN: oxygen-independent coproporphyrinogen III oxidase 25 465 6.3E-126 T 13-10-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.98.3|MetaCyc: PWY-5531 Astex_1452 75215626a33f147d6c33d319d21359c5 466 PIRSF PIRSF000167 12 463 6.2E-153 T 13-10-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.98.3|MetaCyc: PWY-5531 Astex_1452 75215626a33f147d6c33d319d21359c5 466 Pfam PF04055 Radical SAM superfamily 67 237 2.1E-17 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Astex_1452 75215626a33f147d6c33d319d21359c5 466 Gene3D G3DSA:1.10.10.920 374 466 2.5E-18 T 13-10-2018 Astex_1452 75215626a33f147d6c33d319d21359c5 466 SUPERFAMILY SSF102114 20 452 2.22E-108 T 13-10-2018 Astex_0259 5599d4485582824cb6af1a552b952cce 266 Pfam PF03741 Integral membrane protein TerC family 17 222 1.0E-50 T 13-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 Astex_1292 9dc8e51ace4162ca3f8b1b7d9841f22c 365 Pfam PF01070 FMN-dependent dehydrogenase 24 364 2.0E-121 T 13-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 Astex_1292 9dc8e51ace4162ca3f8b1b7d9841f22c 365 PIRSF PIRSF000138 5 365 9.5E-120 T 13-10-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 Reactome: R-HSA-9033241 Astex_1292 9dc8e51ace4162ca3f8b1b7d9841f22c 365 SUPERFAMILY SSF51395 14 363 2.32E-88 T 13-10-2018 Astex_1292 9dc8e51ace4162ca3f8b1b7d9841f22c 365 Gene3D G3DSA:3.20.20.70 12 365 4.2E-128 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_1007 6d7bae031ac8fa45a70ed89044feb759 617 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 128 577 99.087 T 13-10-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 Astex_1007 6d7bae031ac8fa45a70ed89044feb759 617 Pfam PF13667 ThiC-associated domain 17 89 2.9E-20 T 13-10-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 Astex_1007 6d7bae031ac8fa45a70ed89044feb759 617 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 128 576 1.0E-212 T 13-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 Astex_1007 6d7bae031ac8fa45a70ed89044feb759 617 Gene3D G3DSA:3.20.20.540 194 508 4.8E-154 T 13-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 Astex_1007 6d7bae031ac8fa45a70ed89044feb759 617 Pfam PF01964 Radical SAM ThiC family 129 573 1.8E-200 T 13-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 Astex_0421 a8b83f2c95f8d10e30e65b29b2c89379 475 Gene3D G3DSA:3.40.50.300 210 453 1.3E-43 T 13-10-2018 Astex_0421 a8b83f2c95f8d10e30e65b29b2c89379 475 Gene3D G3DSA:3.40.50.2300 80 207 6.2E-43 T 13-10-2018 Astex_0421 a8b83f2c95f8d10e30e65b29b2c89379 475 SUPERFAMILY SSF52172 117 203 4.53E-6 T 13-10-2018 IPR011006 CheY-like superfamily Astex_0421 a8b83f2c95f8d10e30e65b29b2c89379 475 SUPERFAMILY SSF52540 212 453 2.23E-34 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0421 a8b83f2c95f8d10e30e65b29b2c89379 475 Pfam PF06564 Cellulose biosynthesis protein BcsQ 213 360 2.5E-5 T 13-10-2018 IPR017746 Cellulose synthase operon protein BcsQ Astex_1738 00058ba047f007df0a234f7c73e0b694 368 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 119 356 4.0E-85 T 13-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 Astex_1738 00058ba047f007df0a234f7c73e0b694 368 Gene3D G3DSA:3.30.300.130 4 96 8.4E-7 T 13-10-2018 IPR034904 Fe-S cluster assembly domain superfamily Astex_1738 00058ba047f007df0a234f7c73e0b694 368 Pfam PF01883 Iron-sulfur cluster assembly protein 6 77 7.6E-16 T 13-10-2018 IPR002744 MIP18 family-like Astex_1738 00058ba047f007df0a234f7c73e0b694 368 Gene3D G3DSA:3.40.50.300 108 347 2.1E-68 T 13-10-2018 Astex_1738 00058ba047f007df0a234f7c73e0b694 368 Hamap MF_02040 Iron-sulfur cluster carrier protein. 109 354 34.785 T 13-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein Astex_1738 00058ba047f007df0a234f7c73e0b694 368 SUPERFAMILY SSF117916 3 85 1.44E-13 T 13-10-2018 IPR034904 Fe-S cluster assembly domain superfamily Astex_1738 00058ba047f007df0a234f7c73e0b694 368 SUPERFAMILY SSF52540 113 344 1.73E-48 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_3772 508f07b339a50397cbe7b6b9f7f35dcf 1409 SUPERFAMILY SSF52540 413 643 1.02E-12 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_3772 508f07b339a50397cbe7b6b9f7f35dcf 1409 Gene3D G3DSA:3.40.50.300 443 629 1.1E-7 T 13-10-2018 Astex_3772 508f07b339a50397cbe7b6b9f7f35dcf 1409 Pfam PF13872 P-loop containing NTP hydrolase pore-1 380 704 1.6E-105 T 13-10-2018 IPR039187 Strawberry notch, AAA domain Astex_3772 508f07b339a50397cbe7b6b9f7f35dcf 1409 Pfam PF13871 C-terminal domain on Strawberry notch homologue 876 1131 1.2E-83 T 13-10-2018 IPR026937 Strawberry notch, helicase C domain Astex_3772 508f07b339a50397cbe7b6b9f7f35dcf 1409 SUPERFAMILY SSF53335 111 285 1.97E-19 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Astex_3772 508f07b339a50397cbe7b6b9f7f35dcf 1409 Gene3D G3DSA:3.40.50.150 120 286 3.7E-13 T 13-10-2018 Astex_3772 508f07b339a50397cbe7b6b9f7f35dcf 1409 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 205 211 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 Astex_2031 9528f638500f46b0ef7a047437065982 386 SUPERFAMILY SSF47203 232 383 7.73E-47 T 13-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 Astex_2031 9528f638500f46b0ef7a047437065982 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 233 381 2.1E-42 T 13-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Astex_2031 9528f638500f46b0ef7a047437065982 386 PIRSF PIRSF016578 135 386 3.5E-14 T 13-10-2018 Astex_2031 9528f638500f46b0ef7a047437065982 386 PIRSF PIRSF016578 10 100 1.3E-4 T 13-10-2018 Astex_2031 9528f638500f46b0ef7a047437065982 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 14 124 2.3E-37 T 13-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 Astex_2031 9528f638500f46b0ef7a047437065982 386 Gene3D G3DSA:2.40.110.10 127 238 9.0E-44 T 13-10-2018 Astex_2031 9528f638500f46b0ef7a047437065982 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 128 221 1.9E-26 T 13-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 Astex_2031 9528f638500f46b0ef7a047437065982 386 Gene3D G3DSA:1.20.140.10 239 386 2.2E-46 T 13-10-2018 Astex_2031 9528f638500f46b0ef7a047437065982 386 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 130 142 - T 13-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 Astex_2031 9528f638500f46b0ef7a047437065982 386 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 340 359 - T 13-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 Astex_2031 9528f638500f46b0ef7a047437065982 386 SUPERFAMILY SSF56645 3 246 5.37E-84 T 13-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 Astex_2031 9528f638500f46b0ef7a047437065982 386 Gene3D G3DSA:1.10.540.10 2 126 2.3E-46 T 13-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 Astex_1664 04beeda3049b651df3eac343d639d1d9 609 Pfam PF00593 TonB dependent receptor 218 608 9.4E-49 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_1664 04beeda3049b651df3eac343d639d1d9 609 Gene3D G3DSA:2.40.170.20 163 609 1.0E-91 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_1664 04beeda3049b651df3eac343d639d1d9 609 Pfam PF07715 TonB-dependent Receptor Plug Domain 39 146 5.5E-19 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_1664 04beeda3049b651df3eac343d639d1d9 609 SUPERFAMILY SSF56935 25 609 2.52E-103 T 13-10-2018 Astex_1664 04beeda3049b651df3eac343d639d1d9 609 Gene3D G3DSA:2.170.130.10 20 151 2.0E-25 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_0189 89ac454dd89e40e43fe6beb4054f4dc8 740 Gene3D G3DSA:2.170.130.10 63 165 2.4E-9 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_0189 89ac454dd89e40e43fe6beb4054f4dc8 740 Gene3D G3DSA:2.40.170.20 166 716 1.7E-36 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_0189 89ac454dd89e40e43fe6beb4054f4dc8 740 SUPERFAMILY SSF56935 53 712 6.54E-70 T 13-10-2018 Astex_0189 89ac454dd89e40e43fe6beb4054f4dc8 740 Pfam PF14905 Outer membrane protein beta-barrel family 318 710 8.8E-74 T 13-10-2018 Astex_3226 38595f54681f0810dd6af9eba3cf6eee 399 Pfam PF00872 Transposase, Mutator family 4 371 1.7E-125 T 13-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 Astex_2440 38595f54681f0810dd6af9eba3cf6eee 399 Pfam PF00872 Transposase, Mutator family 4 371 1.7E-125 T 13-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 Astex_2327 38595f54681f0810dd6af9eba3cf6eee 399 Pfam PF00872 Transposase, Mutator family 4 371 1.7E-125 T 13-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 Astex_1433 38595f54681f0810dd6af9eba3cf6eee 399 Pfam PF00872 Transposase, Mutator family 4 371 1.7E-125 T 13-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 Astex_2435 26ae1f375fc179951423392a0b185525 276 SUPERFAMILY SSF47413 9 75 2.41E-11 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Astex_2435 26ae1f375fc179951423392a0b185525 276 Pfam PF08281 Sigma-70, region 4 198 248 2.8E-12 T 13-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Astex_2435 26ae1f375fc179951423392a0b185525 276 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 105 250 3.6E-18 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 Astex_2435 26ae1f375fc179951423392a0b185525 276 SMART SM00530 18 73 1.1E-4 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Astex_2435 26ae1f375fc179951423392a0b185525 276 SUPERFAMILY SSF88946 98 177 1.73E-5 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 Astex_2435 26ae1f375fc179951423392a0b185525 276 Pfam PF13560 Helix-turn-helix domain 15 70 4.8E-7 T 13-10-2018 Astex_2435 26ae1f375fc179951423392a0b185525 276 Gene3D G3DSA:1.10.260.40 8 75 3.7E-8 T 13-10-2018 Astex_2435 26ae1f375fc179951423392a0b185525 276 SUPERFAMILY SSF88659 183 257 2.83E-11 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Astex_2435 26ae1f375fc179951423392a0b185525 276 Gene3D G3DSA:1.10.10.10 176 259 3.2E-13 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_2655 6ced88d24cd29de6095eace896d05368 429 SUPERFAMILY SSF53335 125 427 3.54E-55 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Astex_2655 6ced88d24cd29de6095eace896d05368 429 Gene3D G3DSA:3.40.50.150 122 427 1.6E-63 T 13-10-2018 Astex_2655 6ced88d24cd29de6095eace896d05368 429 Pfam PF01189 16S rRNA methyltransferase RsmB/F 228 424 1.5E-38 T 13-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 Astex_2655 6ced88d24cd29de6095eace896d05368 429 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 410 427 1.3E-26 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase Astex_2655 6ced88d24cd29de6095eace896d05368 429 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 231 241 1.3E-26 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase Astex_2655 6ced88d24cd29de6095eace896d05368 429 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 202 216 1.3E-26 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase Astex_2655 6ced88d24cd29de6095eace896d05368 429 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 348 364 1.3E-26 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase Astex_2655 6ced88d24cd29de6095eace896d05368 429 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 298 310 1.3E-26 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase Astex_0680 f212dd412388f02b54603f07cb3754d0 152 SUPERFAMILY SSF54534 76 151 2.88E-22 T 13-10-2018 Astex_0680 f212dd412388f02b54603f07cb3754d0 152 Gene3D G3DSA:1.10.287.180 1 70 1.7E-29 T 13-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 Astex_0680 f212dd412388f02b54603f07cb3754d0 152 Gene3D G3DSA:3.10.50.30 71 152 5.7E-29 T 13-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 Astex_0680 f212dd412388f02b54603f07cb3754d0 152 Hamap MF_00105 Transcription elongation factor GreA [greA]. 1 150 31.914 T 13-10-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 Astex_0680 f212dd412388f02b54603f07cb3754d0 152 PIRSF PIRSF006092 1 151 5.6E-50 T 13-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 Astex_0680 f212dd412388f02b54603f07cb3754d0 152 Pfam PF03449 Transcription elongation factor, N-terminal 1 69 1.2E-30 T 13-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 Astex_0680 f212dd412388f02b54603f07cb3754d0 152 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 1 150 6.4E-61 T 13-10-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 Astex_0680 f212dd412388f02b54603f07cb3754d0 152 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 77 150 1.4E-27 T 13-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 Astex_0680 f212dd412388f02b54603f07cb3754d0 152 SUPERFAMILY SSF46557 1 73 3.14E-27 T 13-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 Astex_0680 f212dd412388f02b54603f07cb3754d0 152 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 12 43 - T 13-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 Astex_0821 c9df76382f53fc87adbf12dd902ad7a6 413 SUPERFAMILY SSF53067 6 172 7.45E-30 T 13-10-2018 Astex_0821 c9df76382f53fc87adbf12dd902ad7a6 413 Gene3D G3DSA:3.30.420.40 174 211 5.3E-39 T 13-10-2018 Astex_0821 c9df76382f53fc87adbf12dd902ad7a6 413 Gene3D G3DSA:3.30.420.40 337 394 2.1E-12 T 13-10-2018 Astex_0821 c9df76382f53fc87adbf12dd902ad7a6 413 Gene3D G3DSA:3.30.420.40 8 173 5.3E-39 T 13-10-2018 Astex_0821 c9df76382f53fc87adbf12dd902ad7a6 413 Gene3D G3DSA:3.90.640.10 287 336 2.1E-12 T 13-10-2018 Astex_0821 c9df76382f53fc87adbf12dd902ad7a6 413 Gene3D G3DSA:3.90.640.10 212 221 5.3E-39 T 13-10-2018 Astex_0821 c9df76382f53fc87adbf12dd902ad7a6 413 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 181 194 - T 13-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 Astex_0821 c9df76382f53fc87adbf12dd902ad7a6 413 SUPERFAMILY SSF53067 177 406 4.82E-29 T 13-10-2018 Astex_0821 c9df76382f53fc87adbf12dd902ad7a6 413 Pfam PF00012 Hsp70 protein 7 221 3.8E-17 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Astex_0821 c9df76382f53fc87adbf12dd902ad7a6 413 Pfam PF00012 Hsp70 protein 287 384 1.4E-5 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 Astex_1876 0647b7ee8e74873e5bc4a37ea733b8ab 138 SUPERFAMILY SSF46785 1 133 9.25E-29 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_1876 0647b7ee8e74873e5bc4a37ea733b8ab 138 Gene3D G3DSA:1.10.10.10 1 137 6.6E-37 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1876 0647b7ee8e74873e5bc4a37ea733b8ab 138 Pfam PF02082 Transcriptional regulator 1 82 2.0E-21 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type Astex_1876 0647b7ee8e74873e5bc4a37ea733b8ab 138 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 133 1.8E-28 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type Astex_1866 3b28b459a0b77934a3b1e885a4b9a6fe 316 Pfam PF08241 Methyltransferase domain 158 254 7.3E-23 T 13-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 Astex_1866 3b28b459a0b77934a3b1e885a4b9a6fe 316 Gene3D G3DSA:1.10.10.10 7 104 1.6E-22 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1866 3b28b459a0b77934a3b1e885a4b9a6fe 316 SUPERFAMILY SSF53335 118 311 7.66E-39 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Astex_1866 3b28b459a0b77934a3b1e885a4b9a6fe 316 Gene3D G3DSA:3.40.50.150 110 291 6.3E-39 T 13-10-2018 Astex_1866 3b28b459a0b77934a3b1e885a4b9a6fe 316 SMART SM00418 14 92 7.1E-24 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Astex_1866 3b28b459a0b77934a3b1e885a4b9a6fe 316 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 48 63 2.5E-14 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Astex_1866 3b28b459a0b77934a3b1e885a4b9a6fe 316 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 63 78 2.5E-14 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Astex_1866 3b28b459a0b77934a3b1e885a4b9a6fe 316 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 16 31 2.5E-14 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Astex_1866 3b28b459a0b77934a3b1e885a4b9a6fe 316 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 35 46 2.5E-14 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Astex_1866 3b28b459a0b77934a3b1e885a4b9a6fe 316 SUPERFAMILY SSF46785 12 117 1.62E-21 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_1866 3b28b459a0b77934a3b1e885a4b9a6fe 316 Pfam PF01022 Bacterial regulatory protein, arsR family 22 66 3.1E-13 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Astex_2139 8051fd4b0d257f0e737930e065a92028 186 Pfam PF13302 Acetyltransferase (GNAT) domain 7 132 5.5E-7 T 13-10-2018 IPR000182 GNAT domain Astex_2139 8051fd4b0d257f0e737930e065a92028 186 SUPERFAMILY SSF55729 5 160 3.35E-23 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Astex_2139 8051fd4b0d257f0e737930e065a92028 186 Gene3D G3DSA:3.40.630.30 1 172 4.3E-27 T 13-10-2018 Astex_2474 94748a6df6d7ebac59f610525fbe1d0b 496 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 195 210 - T 13-10-2018 IPR019826 Carboxylesterase type B, active site Astex_2474 94748a6df6d7ebac59f610525fbe1d0b 496 Gene3D G3DSA:3.40.50.1820 8 490 2.1E-141 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_2474 94748a6df6d7ebac59f610525fbe1d0b 496 Pfam PF00135 Carboxylesterase family 21 474 3.9E-114 T 13-10-2018 IPR002018 Carboxylesterase, type B Astex_2474 94748a6df6d7ebac59f610525fbe1d0b 496 SUPERFAMILY SSF53474 20 472 8.01E-119 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_2474 94748a6df6d7ebac59f610525fbe1d0b 496 ProSitePatterns PS00941 Carboxylesterases type-B signature 2. 97 107 - T 13-10-2018 IPR019819 Carboxylesterase type B, conserved site Astex_0103 e8a0002c3416e7a355abbbbc6f382d39 297 SUPERFAMILY SSF53850 87 294 1.99E-44 T 13-10-2018 Astex_0103 e8a0002c3416e7a355abbbbc6f382d39 297 SUPERFAMILY SSF46785 3 83 1.15E-20 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_0103 e8a0002c3416e7a355abbbbc6f382d39 297 Pfam PF03466 LysR substrate binding domain 87 290 3.0E-40 T 13-10-2018 IPR005119 LysR, substrate-binding Astex_0103 e8a0002c3416e7a355abbbbc6f382d39 297 Gene3D G3DSA:3.40.190.290 89 292 7.0E-62 T 13-10-2018 Astex_0103 e8a0002c3416e7a355abbbbc6f382d39 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 4.1E-17 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_0103 e8a0002c3416e7a355abbbbc6f382d39 297 Gene3D G3DSA:1.10.10.10 2 87 1.9E-25 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1529 853527976fe29f3548e2795c28e8ef84 231 Gene3D G3DSA:3.40.50.10610 30 222 1.4E-28 T 13-10-2018 Astex_1529 853527976fe29f3548e2795c28e8ef84 231 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 67 203 2.4E-11 T 13-10-2018 IPR005586 ABC-type transport auxiliary lipoprotein component Astex_1529 853527976fe29f3548e2795c28e8ef84 231 SUPERFAMILY SSF159594 55 213 1.1E-25 T 13-10-2018 Astex_0373 72a52ebf677b567d06d40aa24fe9887e 278 Pfam PF13276 HTH-like domain 43 92 6.7E-20 T 13-10-2018 IPR025948 HTH-like domain Astex_0373 72a52ebf677b567d06d40aa24fe9887e 278 Pfam PF00665 Integrase core domain 118 230 1.8E-22 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 Astex_0373 72a52ebf677b567d06d40aa24fe9887e 278 SUPERFAMILY SSF53098 112 270 5.92E-30 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily Astex_0373 72a52ebf677b567d06d40aa24fe9887e 278 Gene3D G3DSA:3.30.420.10 116 273 8.5E-8 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Astex_1558 72a52ebf677b567d06d40aa24fe9887e 278 Pfam PF13276 HTH-like domain 43 92 6.7E-20 T 13-10-2018 IPR025948 HTH-like domain Astex_1558 72a52ebf677b567d06d40aa24fe9887e 278 Pfam PF00665 Integrase core domain 118 230 1.8E-22 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 Astex_1558 72a52ebf677b567d06d40aa24fe9887e 278 SUPERFAMILY SSF53098 112 270 5.92E-30 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily Astex_1558 72a52ebf677b567d06d40aa24fe9887e 278 Gene3D G3DSA:3.30.420.10 116 273 8.5E-8 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Astex_0055 8313ef5767eff5269dd4ab4c024dcf81 311 Pfam PF01738 Dienelactone hydrolase family 69 310 1.0E-49 T 13-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 Astex_0055 8313ef5767eff5269dd4ab4c024dcf81 311 SUPERFAMILY SSF53474 57 311 3.01E-44 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_0055 8313ef5767eff5269dd4ab4c024dcf81 311 Gene3D G3DSA:3.40.50.1820 52 310 2.6E-58 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_0270 4610d258a5063cffb680c1c8cd4f1939 229 Hamap MF_00189 Probable intracellular septation protein A [yciB]. 37 223 14.25 T 13-10-2018 IPR006008 Intracellular septation protein A GO:0016021 Astex_0270 4610d258a5063cffb680c1c8cd4f1939 229 Pfam PF04279 Intracellular septation protein A 38 221 4.4E-39 T 13-10-2018 IPR006008 Intracellular septation protein A GO:0016021 Astex_1586 a6bd191ee2e831a54f462b1e94d24c6b 121 Pfam PF03551 Transcriptional regulator PadR-like family 18 87 8.7E-20 T 13-10-2018 IPR005149 Transcription regulator PadR, N-terminal Astex_1586 a6bd191ee2e831a54f462b1e94d24c6b 121 SUPERFAMILY SSF46785 14 106 6.21E-26 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_1586 a6bd191ee2e831a54f462b1e94d24c6b 121 Gene3D G3DSA:1.10.10.10 4 115 5.8E-32 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_2172 1c2ad08c4bdb51f69d3960cba8bd4832 106 SUPERFAMILY SSF54913 4 105 7.41E-33 T 13-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta Astex_2172 1c2ad08c4bdb51f69d3960cba8bd4832 106 Gene3D G3DSA:3.30.70.120 1 106 1.0E-33 T 13-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal Astex_2172 1c2ad08c4bdb51f69d3960cba8bd4832 106 Pfam PF03091 CutA1 divalent ion tolerance protein 8 103 5.6E-32 T 13-10-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 Astex_2396 a339c96b57c81fdaccfe93f5edbe8fd3 224 Gene3D G3DSA:3.30.1150.10 100 224 9.1E-30 T 13-10-2018 Astex_2396 a339c96b57c81fdaccfe93f5edbe8fd3 224 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 146 210 1.3E-14 T 13-10-2018 IPR037682 TonB, C-terminal GO:0055085 Astex_2396 a339c96b57c81fdaccfe93f5edbe8fd3 224 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 147 221 7.6E-19 T 13-10-2018 IPR006260 TonB/TolA, C-terminal Astex_2396 a339c96b57c81fdaccfe93f5edbe8fd3 224 SUPERFAMILY SSF74653 110 221 3.92E-19 T 13-10-2018 Astex_2505 3d70797e877c8d99d61739b216675ca0 207 Pfam PF01169 Uncharacterized protein family UPF0016 24 98 1.6E-18 T 13-10-2018 IPR001727 Gdt1 family Astex_2505 3d70797e877c8d99d61739b216675ca0 207 Pfam PF01169 Uncharacterized protein family UPF0016 121 197 4.2E-21 T 13-10-2018 IPR001727 Gdt1 family Astex_2457 e22096399062d3315d96dacac894ecec 362 Pfam PF01548 Transposase 5 150 1.1E-15 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 Astex_2457 e22096399062d3315d96dacac894ecec 362 Pfam PF02371 Transposase IS116/IS110/IS902 family 213 292 2.6E-23 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 Astex_0075 e22096399062d3315d96dacac894ecec 362 Pfam PF01548 Transposase 5 150 1.1E-15 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 Astex_0075 e22096399062d3315d96dacac894ecec 362 Pfam PF02371 Transposase IS116/IS110/IS902 family 213 292 2.6E-23 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 Astex_3687 a004d4e16ed851afb3752d1e7f556c57 173 SUPERFAMILY SSF47240 2 155 2.78E-57 T 13-10-2018 IPR009078 Ferritin-like superfamily Astex_3687 a004d4e16ed851afb3752d1e7f556c57 173 Pfam PF05974 Domain of unknown function (DUF892) 6 162 4.0E-62 T 13-10-2018 IPR010287 Domain of unknown function DUF892 Astex_3687 a004d4e16ed851afb3752d1e7f556c57 173 Gene3D G3DSA:1.20.1260.10 1 166 1.2E-67 T 13-10-2018 IPR012347 Ferritin-like Astex_3504 c8ac74c0786ec97f11cb3c101b48b2cd 298 SUPERFAMILY SSF51261 142 293 5.36E-42 T 13-10-2018 IPR011055 Duplicated hybrid motif Astex_3504 c8ac74c0786ec97f11cb3c101b48b2cd 298 Gene3D G3DSA:2.70.70.10 139 296 1.4E-37 T 13-10-2018 IPR011055 Duplicated hybrid motif Astex_3504 c8ac74c0786ec97f11cb3c101b48b2cd 298 Pfam PF01551 Peptidase family M23 194 289 4.6E-26 T 13-10-2018 IPR016047 Peptidase M23 Astex_1839 cb58a65ebc766a07cdd58158a1b37699 315 SUPERFAMILY SSF51412 6 294 2.9E-54 T 13-10-2018 Astex_1839 cb58a65ebc766a07cdd58158a1b37699 315 Gene3D G3DSA:3.20.20.70 6 313 7.4E-67 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_1839 cb58a65ebc766a07cdd58158a1b37699 315 Pfam PF03060 Nitronate monooxygenase 10 299 8.6E-28 T 13-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 Astex_2344 63944d40c88b2ae8ff26bc22f71a74d4 216 SUPERFAMILY SSF46689 18 83 5.99E-14 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Astex_2344 63944d40c88b2ae8ff26bc22f71a74d4 216 SUPERFAMILY SSF48498 94 215 1.46E-10 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily Astex_2344 63944d40c88b2ae8ff26bc22f71a74d4 216 Gene3D G3DSA:1.10.357.10 8 215 8.0E-33 T 13-10-2018 Astex_2344 63944d40c88b2ae8ff26bc22f71a74d4 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 74 8.6E-12 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Astex_2344 63944d40c88b2ae8ff26bc22f71a74d4 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 41 4.4E-6 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Astex_2344 63944d40c88b2ae8ff26bc22f71a74d4 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 49 72 4.4E-6 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Astex_3143 280a118d8114ac6c183b7e840bc5fc0e 155 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 5 146 3.4E-33 T 13-10-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like Astex_3143 280a118d8114ac6c183b7e840bc5fc0e 155 Gene3D G3DSA:3.30.1330.40 1 152 4.7E-60 T 13-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 Astex_3143 280a118d8114ac6c183b7e840bc5fc0e 155 SUPERFAMILY SSF55298 1 151 1.41E-53 T 13-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 Astex_2770 391a3c281a0f4046e06716925afd631b 252 Pfam PF01553 Acyltransferase 56 179 3.4E-15 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 Astex_2770 391a3c281a0f4046e06716925afd631b 252 SMART SM00563 69 183 3.0E-15 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 Astex_2770 391a3c281a0f4046e06716925afd631b 252 SUPERFAMILY SSF69593 31 236 1.14E-25 T 13-10-2018 Astex_3522 09f9600e89c34aaa5a12264062d5154a 654 Pfam PF00563 EAL domain 408 631 9.3E-64 T 13-10-2018 IPR001633 EAL domain Astex_3522 09f9600e89c34aaa5a12264062d5154a 654 SMART SM00052 386 636 5.5E-77 T 13-10-2018 IPR001633 EAL domain Astex_3522 09f9600e89c34aaa5a12264062d5154a 654 SMART SM00267 211 384 1.3E-45 T 13-10-2018 IPR000160 GGDEF domain Astex_3522 09f9600e89c34aaa5a12264062d5154a 654 Gene3D G3DSA:3.30.70.270 220 397 5.6E-44 T 13-10-2018 Astex_3522 09f9600e89c34aaa5a12264062d5154a 654 SUPERFAMILY SSF55073 227 385 6.04E-39 T 13-10-2018 IPR029787 Nucleotide cyclase Astex_3522 09f9600e89c34aaa5a12264062d5154a 654 SUPERFAMILY SSF141868 402 642 7.45E-78 T 13-10-2018 IPR035919 EAL domain superfamily Astex_3522 09f9600e89c34aaa5a12264062d5154a 654 Pfam PF00990 Diguanylate cyclase, GGDEF domain 222 378 6.7E-36 T 13-10-2018 IPR000160 GGDEF domain Astex_3522 09f9600e89c34aaa5a12264062d5154a 654 Gene3D G3DSA:3.20.20.450 398 651 4.4E-81 T 13-10-2018 IPR035919 EAL domain superfamily Astex_3522 09f9600e89c34aaa5a12264062d5154a 654 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 220 379 2.1E-29 T 13-10-2018 IPR000160 GGDEF domain Astex_0105 d270900c935ed58128cec7c54cc07134 245 SUPERFAMILY SSF63380 9 121 2.46E-14 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel Astex_0105 d270900c935ed58128cec7c54cc07134 245 Gene3D G3DSA:3.40.50.80 120 245 8.4E-31 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain Astex_0105 d270900c935ed58128cec7c54cc07134 245 Gene3D G3DSA:2.40.30.10 5 118 3.3E-29 T 13-10-2018 Astex_0105 d270900c935ed58128cec7c54cc07134 245 Pfam PF08021 Siderophore-interacting FAD-binding domain 61 117 5.5E-17 T 13-10-2018 IPR013113 FAD-binding 9, siderophore-interacting Astex_0105 d270900c935ed58128cec7c54cc07134 245 Pfam PF04954 Siderophore-interacting protein 125 236 7.7E-27 T 13-10-2018 IPR007037 Siderophore-interacting protein, C-terminal domain Astex_0920 aa2718529b4e7d51b17958f459eb8455 285 Pfam PF01112 Asparaginase 4 277 3.6E-75 T 13-10-2018 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 Astex_0920 aa2718529b4e7d51b17958f459eb8455 285 Gene3D G3DSA:3.60.20.30 156 285 9.1E-39 T 13-10-2018 Astex_0920 aa2718529b4e7d51b17958f459eb8455 285 SUPERFAMILY SSF56235 2 279 9.77E-73 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Astex_2882 21276790bc96e67f2963639eea71e825 77 SUPERFAMILY SSF64307 7 77 1.44E-18 T 13-10-2018 IPR036868 TusA-like domain superfamily Astex_2882 21276790bc96e67f2963639eea71e825 77 Pfam PF01206 Sulfurtransferase TusA 11 77 3.0E-18 T 13-10-2018 IPR001455 TusA-like domain Astex_2882 21276790bc96e67f2963639eea71e825 77 Gene3D G3DSA:3.30.110.40 3 77 5.2E-22 T 13-10-2018 IPR036868 TusA-like domain superfamily Astex_1794 82bd475310f9f019fe4542e07f7e56cb 506 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 273 280 - T 13-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 Astex_1794 82bd475310f9f019fe4542e07f7e56cb 506 Gene3D G3DSA:3.40.309.10 278 470 1.4E-180 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 Astex_1794 82bd475310f9f019fe4542e07f7e56cb 506 SUPERFAMILY SSF53720 22 503 9.56E-168 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 Astex_1794 82bd475310f9f019fe4542e07f7e56cb 506 Pfam PF00171 Aldehyde dehydrogenase family 35 500 1.6E-172 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 Astex_1794 82bd475310f9f019fe4542e07f7e56cb 506 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 302 313 - T 13-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 Astex_1794 82bd475310f9f019fe4542e07f7e56cb 506 Gene3D G3DSA:3.40.605.10 32 498 1.4E-180 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 Astex_0226 9e8577a2e04a411b71f3784d7b9ee939 316 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 185 311 9.9E-23 T 13-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like Astex_0226 9e8577a2e04a411b71f3784d7b9ee939 316 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 32 168 1.7E-33 T 13-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like Astex_0226 9e8577a2e04a411b71f3784d7b9ee939 316 SUPERFAMILY SSF55961 19 168 2.04E-44 T 13-10-2018 Astex_0226 9e8577a2e04a411b71f3784d7b9ee939 316 SUPERFAMILY SSF55961 175 313 1.06E-32 T 13-10-2018 Astex_0226 9e8577a2e04a411b71f3784d7b9ee939 316 Gene3D G3DSA:3.30.530.20 171 314 1.1E-33 T 13-10-2018 IPR023393 START-like domain superfamily Astex_0226 9e8577a2e04a411b71f3784d7b9ee939 316 Gene3D G3DSA:3.30.530.20 9 170 7.1E-51 T 13-10-2018 IPR023393 START-like domain superfamily Astex_3157 3882d443ed412a10b114d01c67a94952 305 SUPERFAMILY SSF53448 14 245 4.41E-32 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_3157 3882d443ed412a10b114d01c67a94952 305 Pfam PF00535 Glycosyl transferase family 2 20 134 1.2E-17 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 Astex_3157 3882d443ed412a10b114d01c67a94952 305 Gene3D G3DSA:3.90.550.10 3 221 4.4E-28 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_3198 f5bdad3326419b530ca879e9a9978023 201 Pfam PF06940 Domain of unknown function (DUF1287) 35 199 4.8E-64 T 13-10-2018 IPR009706 Protein of unknown function DUF1287 Astex_3198 f5bdad3326419b530ca879e9a9978023 201 PIRSF PIRSF011444 16 201 1.0E-68 T 13-10-2018 IPR009706 Protein of unknown function DUF1287 Astex_3198 f5bdad3326419b530ca879e9a9978023 201 ProDom PD357862 YIJF PERIPLASMIC ECS4873 PRECURSOR CC1379 SIGNAL DOMAIN PM0035 32 198 3.0E-46 T 13-10-2018 IPR009706 Protein of unknown function DUF1287 Astex_0533 c3b752707091f124e42d15826458a691 305 Pfam PF00756 Putative esterase 65 252 3.6E-25 T 13-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 Astex_0533 c3b752707091f124e42d15826458a691 305 Gene3D G3DSA:3.40.50.1820 58 303 4.3E-63 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_0533 c3b752707091f124e42d15826458a691 305 SUPERFAMILY SSF53474 57 301 8.01E-45 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_0220 6bf2abc438d04b665ef89ba0e453184f 480 Gene3D G3DSA:1.10.287.130 211 291 2.7E-10 T 13-10-2018 Astex_0220 6bf2abc438d04b665ef89ba0e453184f 480 SMART SM00387 347 461 2.3E-15 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_0220 6bf2abc438d04b665ef89ba0e453184f 480 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 439 2.7E-5 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_0220 6bf2abc438d04b665ef89ba0e453184f 480 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 396 2.7E-5 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_0220 6bf2abc438d04b665ef89ba0e453184f 480 SUPERFAMILY SSF55874 339 460 3.93E-21 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_0220 6bf2abc438d04b665ef89ba0e453184f 480 Gene3D G3DSA:3.30.565.10 292 456 3.5E-17 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_0220 6bf2abc438d04b665ef89ba0e453184f 480 Pfam PF00512 His Kinase A (phospho-acceptor) domain 235 294 1.1E-6 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_0220 6bf2abc438d04b665ef89ba0e453184f 480 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 354 454 9.1E-13 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_0220 6bf2abc438d04b665ef89ba0e453184f 480 SUPERFAMILY SSF47384 222 291 6.08E-7 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Astex_0220 6bf2abc438d04b665ef89ba0e453184f 480 SMART SM00388 234 297 1.2E-4 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_0281 92a764037330cb9d205fce72ee8a9c4d 350 SUPERFAMILY SSF52467 8 343 3.92E-91 T 13-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily Astex_0281 92a764037330cb9d205fce72ee8a9c4d 350 Pfam PF01916 Deoxyhypusine synthase 32 328 2.1E-84 T 13-10-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 Astex_0281 92a764037330cb9d205fce72ee8a9c4d 350 Gene3D G3DSA:3.40.910.10 6 337 1.1E-79 T 13-10-2018 IPR036982 Deoxyhypusine synthase superfamily GO:0008612 Reactome: R-HSA-204626 Astex_0281 92a764037330cb9d205fce72ee8a9c4d 350 Hamap MF_00640 Deoxyhypusine synthase-like protein. 11 350 54.38 T 13-10-2018 IPR023496 Deoxyhypusine synthase-like GO:0016765 Astex_2141 a8205727ee903282154107fe5cc9f0e6 337 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 239 324 4.4E-20 T 13-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 Astex_2141 a8205727ee903282154107fe5cc9f0e6 337 SUPERFAMILY SSF53901 30 325 6.53E-38 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 Astex_2141 a8205727ee903282154107fe5cc9f0e6 337 Gene3D G3DSA:3.40.47.10 3 336 1.8E-94 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 Astex_2141 a8205727ee903282154107fe5cc9f0e6 337 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 113 188 2.6E-14 T 13-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 Astex_1241 be014a9b2ce9c9c07fc22c5af82ea83b 232 Pfam PF00494 Squalene/phytoene synthase 22 110 1.1E-7 T 13-10-2018 Astex_1241 be014a9b2ce9c9c07fc22c5af82ea83b 232 SUPERFAMILY SSF48576 23 231 2.3E-6 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily Astex_0399 e62c7dd35b5a6ffa3f58e4ad79bfa71b 223 Gene3D G3DSA:3.40.50.620 25 222 7.6E-41 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Astex_0399 e62c7dd35b5a6ffa3f58e4ad79bfa71b 223 SUPERFAMILY SSF52374 26 214 2.0E-39 T 13-10-2018 Astex_0399 e62c7dd35b5a6ffa3f58e4ad79bfa71b 223 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 32 215 5.2E-36 T 13-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 Astex_0399 e62c7dd35b5a6ffa3f58e4ad79bfa71b 223 Pfam PF01467 Cytidylyltransferase-like 32 210 4.5E-24 T 13-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 Astex_0399 e62c7dd35b5a6ffa3f58e4ad79bfa71b 223 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 28 210 21.312 T 13-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 Astex_3616 f08a4e55268501efcd2a9f8381940455 372 Pfam PF07786 Protein of unknown function (DUF1624) 5 233 7.6E-10 T 13-10-2018 IPR012429 Domain of unknown function DUF1624 Reactome: R-HSA-2024096|Reactome: R-HSA-2206291|Reactome: R-HSA-6798695 Astex_0175 29ce95e7e9a6fd4c526019cd13c03a03 222 SUPERFAMILY SSF74942 92 163 4.58E-13 T 13-10-2018 IPR036847 Ribosome maturation factor RimP, C-terminal domain superfamily Astex_0175 29ce95e7e9a6fd4c526019cd13c03a03 222 SUPERFAMILY SSF75420 8 91 5.23E-17 T 13-10-2018 IPR035956 RimP, N-terminal domain superfamily Astex_0175 29ce95e7e9a6fd4c526019cd13c03a03 222 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 9 162 20.99 T 13-10-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 Astex_0175 29ce95e7e9a6fd4c526019cd13c03a03 222 Pfam PF17384 RimP C-terminal SH3 domain 94 160 8.3E-9 T 13-10-2018 IPR028998 Ribosome maturation factor RimP, C-terminal Astex_0175 29ce95e7e9a6fd4c526019cd13c03a03 222 Pfam PF02576 RimP N-terminal domain 16 91 5.3E-19 T 13-10-2018 IPR028989 Ribosome maturation factor RimP, N-terminal Astex_0175 29ce95e7e9a6fd4c526019cd13c03a03 222 Gene3D G3DSA:3.30.300.70 5 88 7.6E-12 T 13-10-2018 IPR035956 RimP, N-terminal domain superfamily Astex_2509 a03871ce06be82727f3e8eb58f0fa44e 351 Gene3D G3DSA:2.60.120.260 24 124 6.0E-20 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_2509 a03871ce06be82727f3e8eb58f0fa44e 351 SUPERFAMILY SSF52266 132 345 4.33E-21 T 13-10-2018 Astex_2509 a03871ce06be82727f3e8eb58f0fa44e 351 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 136 315 3.7E-13 T 13-10-2018 IPR013830 SGNH hydrolase-type esterase domain Astex_2509 a03871ce06be82727f3e8eb58f0fa44e 351 Gene3D G3DSA:3.40.50.1110 128 351 1.8E-60 T 13-10-2018 IPR036514 SGNH hydrolase superfamily Astex_3341 38f8ec26b0ff1d7d6d0d5c13d55c1a75 317 SUPERFAMILY SSF51735 5 305 4.94E-31 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_3341 38f8ec26b0ff1d7d6d0d5c13d55c1a75 317 Gene3D G3DSA:3.40.50.720 4 309 3.2E-25 T 13-10-2018 Astex_3341 38f8ec26b0ff1d7d6d0d5c13d55c1a75 317 Pfam PF01370 NAD dependent epimerase/dehydratase family 11 214 4.3E-12 T 13-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 Astex_3082 26c750c5e0a96be498e9b97d7b742b6b 369 SUPERFAMILY SSF50129 1 181 3.2E-68 T 13-10-2018 IPR011032 GroES-like superfamily Astex_3082 26c750c5e0a96be498e9b97d7b742b6b 369 TIGRFAM TIGR02818 adh_III_F_hyde: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 2 368 2.1E-185 T 13-10-2018 IPR014183 Alcohol dehydrogenase class III GO:0006069|GO:0008270|GO:0051903|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00680+1.1.1.284|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-1801|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396|MetaCyc: PWY-7798|Reactome: R-HSA-71384 Astex_3082 26c750c5e0a96be498e9b97d7b742b6b 369 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 126 3.4E-23 T 13-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 Astex_3082 26c750c5e0a96be498e9b97d7b742b6b 369 Gene3D G3DSA:3.90.180.10 6 364 2.9E-143 T 13-10-2018 Astex_3082 26c750c5e0a96be498e9b97d7b742b6b 369 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 13-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 Astex_3082 26c750c5e0a96be498e9b97d7b742b6b 369 Pfam PF00107 Zinc-binding dehydrogenase 197 320 7.5E-22 T 13-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 Astex_3082 26c750c5e0a96be498e9b97d7b742b6b 369 Gene3D G3DSA:3.40.50.720 174 312 2.9E-143 T 13-10-2018 Astex_3082 26c750c5e0a96be498e9b97d7b742b6b 369 SUPERFAMILY SSF51735 160 334 2.63E-44 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_3082 26c750c5e0a96be498e9b97d7b742b6b 369 SMART SM00829 13 367 0.0071 T 13-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 Astex_3082 26c750c5e0a96be498e9b97d7b742b6b 369 SUPERFAMILY SSF50129 319 369 9.89E-13 T 13-10-2018 IPR011032 GroES-like superfamily Astex_0781 0ac5301c138cf708d133ca59442d7e91 172 Pfam PF07977 FabA-like domain 29 158 3.9E-51 T 13-10-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 Astex_0781 0ac5301c138cf708d133ca59442d7e91 172 Gene3D G3DSA:3.10.129.10 3 171 6.0E-64 T 13-10-2018 Astex_0781 0ac5301c138cf708d133ca59442d7e91 172 SUPERFAMILY SSF54637 4 168 4.81E-56 T 13-10-2018 IPR029069 HotDog domain superfamily Astex_0781 0ac5301c138cf708d133ca59442d7e91 172 Hamap MF_00405 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase [fabA]. 2 172 49.9 T 13-10-2018 IPR010083 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA GO:0005737|GO:0006633|GO:0008693 KEGG: 00061+4.2.1.59+5.3.3.14|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 Astex_0781 0ac5301c138cf708d133ca59442d7e91 172 TIGRFAM TIGR01749 fabA: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA 6 170 7.7E-90 T 13-10-2018 IPR010083 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA GO:0005737|GO:0006633|GO:0008693 KEGG: 00061+4.2.1.59+5.3.3.14|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 Astex_0724 0d8435505495e63ff5e353deb6338076 295 Gene3D G3DSA:2.40.100.10 12 251 3.2E-19 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily Astex_0724 0d8435505495e63ff5e353deb6338076 295 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 56 237 2.5E-17 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 Astex_0724 0d8435505495e63ff5e353deb6338076 295 SUPERFAMILY SSF50891 50 254 1.02E-18 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily Astex_1392 28b946f68c33268af3939f81d7cc14cb 267 Hamap MF_00013 Octanoyltransferase [lipB]. 33 261 34.429 T 13-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 Astex_1392 28b946f68c33268af3939f81d7cc14cb 267 Pfam PF03099 Biotin/lipoate A/B protein ligase family 86 214 1.1E-4 T 13-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 Astex_1392 28b946f68c33268af3939f81d7cc14cb 267 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 64 163 7.7E-27 T 13-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 Astex_1392 28b946f68c33268af3939f81d7cc14cb 267 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 105 157 1.0E-17 T 13-10-2018 Astex_1392 28b946f68c33268af3939f81d7cc14cb 267 SUPERFAMILY SSF55681 36 260 3.73E-63 T 13-10-2018 Astex_1392 28b946f68c33268af3939f81d7cc14cb 267 PIRSF PIRSF016262 33 264 6.3E-56 T 13-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 Astex_1392 28b946f68c33268af3939f81d7cc14cb 267 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 100 115 - T 13-10-2018 IPR020605 Octanoyltransferase, conserved site GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 Astex_1392 28b946f68c33268af3939f81d7cc14cb 267 Gene3D G3DSA:3.30.930.10 34 258 6.0E-60 T 13-10-2018 Astex_3237 42da2e9226af42f69b2cf236b372a5da 84 Gene3D G3DSA:1.10.8.1250 14 84 3.8E-5 T 13-10-2018 IPR038296 Antitoxin ParD superfamily Astex_3237 42da2e9226af42f69b2cf236b372a5da 84 SUPERFAMILY SSF47598 3 47 6.34E-5 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 Astex_1108 36425e8bbb7aa2f73c6513613dd325b7 234 SMART SM00448 6 116 2.6E-37 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1108 36425e8bbb7aa2f73c6513613dd325b7 234 SUPERFAMILY SSF52172 6 186 2.42E-37 T 13-10-2018 IPR011006 CheY-like superfamily Astex_1108 36425e8bbb7aa2f73c6513613dd325b7 234 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 227 7.5E-21 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Astex_1108 36425e8bbb7aa2f73c6513613dd325b7 234 Pfam PF00072 Response regulator receiver domain 8 116 1.8E-25 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1108 36425e8bbb7aa2f73c6513613dd325b7 234 SMART SM00862 151 227 5.1E-21 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Astex_1108 36425e8bbb7aa2f73c6513613dd325b7 234 Gene3D G3DSA:1.10.10.10 130 232 5.3E-30 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1108 36425e8bbb7aa2f73c6513613dd325b7 234 Gene3D G3DSA:3.40.50.2300 2 129 9.7E-33 T 13-10-2018 Astex_1420 22bd3d22446b9c910595255293c6d9b6 140 Pfam PF00460 Flagella basal body rod protein 13 41 4.7E-8 T 13-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 Astex_1420 22bd3d22446b9c910595255293c6d9b6 140 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 92 137 6.9E-10 T 13-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain Astex_1420 22bd3d22446b9c910595255293c6d9b6 140 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 12 139 8.2E-42 T 13-10-2018 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 Astex_3011 67b186d571eff7d6dd2711cf2216b67c 131 Pfam PF05071 NADH ubiquinone oxidoreductase subunit NDUFA12 25 131 6.1E-25 T 13-10-2018 IPR007763 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 GO:0008137|GO:0009055|GO:0016020 Reactome: R-HSA-6799198 Astex_3301 bf7c980e9d302954d71603f15c719994 446 SMART SM00471 51 260 4.0E-9 T 13-10-2018 IPR003607 HD/PDEase domain Astex_3301 bf7c980e9d302954d71603f15c719994 446 SUPERFAMILY SSF109604 22 438 1.26E-66 T 13-10-2018 Astex_3301 bf7c980e9d302954d71603f15c719994 446 Pfam PF01966 HD domain 55 138 1.6E-9 T 13-10-2018 IPR006674 HD domain Astex_3301 bf7c980e9d302954d71603f15c719994 446 Pfam PF13286 Phosphohydrolase-associated domain 351 433 1.1E-23 T 13-10-2018 IPR026875 Phosphohydrolase-associated domain Astex_3301 bf7c980e9d302954d71603f15c719994 446 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 1 435 30.245 T 13-10-2018 IPR023023 dNTP triphosphohydrolase, type 2 GO:0016793 Astex_3301 bf7c980e9d302954d71603f15c719994 446 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 22 436 2.8E-97 T 13-10-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 Astex_0353 8d3cd2956bf53eccdee6b988e0d0cc96 107 Pfam PF16083 LydA holin phage, holin superfamily III 16 92 2.3E-18 T 13-10-2018 IPR032126 LydA-like holin Astex_0009 4fb707020706f9209cd5d1748875a84c 673 Pfam PF02705 K+ potassium transporter 53 595 5.7E-195 T 13-10-2018 IPR003855 Potassium transporter GO:0015079|GO:0016020|GO:0071805 Astex_0009 4fb707020706f9209cd5d1748875a84c 673 Hamap MF_01522 Low affinity potassium transport system protein kup [kup]. 44 673 32.67 T 13-10-2018 IPR023051 Potassium uptake protein, low affinity, Kup Astex_1768 cdc7a4d0d18c94759513c5924a7f95bd 287 SUPERFAMILY SSF56281 31 284 2.2E-40 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Astex_1768 cdc7a4d0d18c94759513c5924a7f95bd 287 Pfam PF00753 Metallo-beta-lactamase superfamily 83 265 1.8E-21 T 13-10-2018 IPR001279 Metallo-beta-lactamase Astex_1768 cdc7a4d0d18c94759513c5924a7f95bd 287 Gene3D G3DSA:3.60.15.10 28 287 7.1E-76 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Astex_1768 cdc7a4d0d18c94759513c5924a7f95bd 287 SMART SM00849 83 265 3.7E-19 T 13-10-2018 IPR001279 Metallo-beta-lactamase Astex_1025 8744af0f423c1ddd99612071657887b7 169 Gene3D G3DSA:3.40.50.850 3 169 4.2E-22 T 13-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 Astex_1025 8744af0f423c1ddd99612071657887b7 169 Pfam PF00857 Isochorismatase family 6 154 4.8E-18 T 13-10-2018 IPR000868 Isochorismatase-like GO:0003824 Astex_1025 8744af0f423c1ddd99612071657887b7 169 SUPERFAMILY SSF52499 5 155 3.27E-22 T 13-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 Astex_1733 e6e4f629ed64f54ef605f7b8436163c0 173 PIRSF PIRSF000194 1 172 2.5E-58 T 13-10-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0046654|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614 Astex_1733 e6e4f629ed64f54ef605f7b8436163c0 173 PRINTS PR00070 Dihydrofolate reductase signature 17 27 4.5E-14 T 13-10-2018 Astex_1733 e6e4f629ed64f54ef605f7b8436163c0 173 PRINTS PR00070 Dihydrofolate reductase signature 44 55 4.5E-14 T 13-10-2018 Astex_1733 e6e4f629ed64f54ef605f7b8436163c0 173 PRINTS PR00070 Dihydrofolate reductase signature 102 116 4.5E-14 T 13-10-2018 Astex_1733 e6e4f629ed64f54ef605f7b8436163c0 173 PRINTS PR00070 Dihydrofolate reductase signature 31 39 4.5E-14 T 13-10-2018 Astex_1733 e6e4f629ed64f54ef605f7b8436163c0 173 SUPERFAMILY SSF53597 5 171 3.93E-56 T 13-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 Astex_1733 e6e4f629ed64f54ef605f7b8436163c0 173 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 17 39 - T 13-10-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 Astex_1733 e6e4f629ed64f54ef605f7b8436163c0 173 Pfam PF00186 Dihydrofolate reductase 6 170 3.0E-54 T 13-10-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0046654|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 Astex_1733 e6e4f629ed64f54ef605f7b8436163c0 173 Gene3D G3DSA:3.40.430.10 5 173 1.3E-56 T 13-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 Astex_3547 d25b4180b1c0ba1a09f20f110df2042a 448 Pfam PF15892 BNR repeat-containing family member 57 323 1.6E-85 T 13-10-2018 IPR039469 BNR repeat-containing family member Astex_3547 d25b4180b1c0ba1a09f20f110df2042a 448 Gene3D G3DSA:2.115.10.20 203 334 1.4E-6 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Astex_2140 1f08e620390e308b09255f27ea805705 328 Gene3D G3DSA:3.40.50.2000 151 275 1.7E-24 T 13-10-2018 Astex_2140 1f08e620390e308b09255f27ea805705 328 TIGRFAM TIGR03590 PseG: UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase 2 268 2.3E-52 T 13-10-2018 IPR020023 UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase Astex_2140 1f08e620390e308b09255f27ea805705 328 Gene3D G3DSA:3.40.50.11190 1 149 3.8E-16 T 13-10-2018 Astex_2140 1f08e620390e308b09255f27ea805705 328 SUPERFAMILY SSF53756 149 327 4.54E-12 T 13-10-2018 Astex_0612 98dac63d204f41db2502f98d0cc87553 280 SUPERFAMILY SSF47757 1 70 6.41E-12 T 13-10-2018 Astex_0612 98dac63d204f41db2502f98d0cc87553 280 SUPERFAMILY SSF53335 71 263 3.0E-49 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Astex_0612 98dac63d204f41db2502f98d0cc87553 280 Pfam PF01739 CheR methyltransferase, SAM binding domain 71 258 1.3E-59 T 13-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal Astex_0612 98dac63d204f41db2502f98d0cc87553 280 Gene3D G3DSA:3.40.50.150 70 267 7.9E-58 T 13-10-2018 Astex_0612 98dac63d204f41db2502f98d0cc87553 280 SMART SM00138 3 265 1.1E-88 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Astex_0612 98dac63d204f41db2502f98d0cc87553 280 Gene3D G3DSA:1.10.155.10 1 69 4.9E-5 T 13-10-2018 IPR036804 Chemotaxis receptor methyltransferase CheR, N-terminal domain superfamily Astex_0612 98dac63d204f41db2502f98d0cc87553 280 Pfam PF03705 CheR methyltransferase, all-alpha domain 5 54 5.3E-9 T 13-10-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal Astex_0612 98dac63d204f41db2502f98d0cc87553 280 PRINTS PR00996 Glutamate methyltransferase family signature 64 76 3.0E-40 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Astex_0612 98dac63d204f41db2502f98d0cc87553 280 PRINTS PR00996 Glutamate methyltransferase family signature 102 122 3.0E-40 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Astex_0612 98dac63d204f41db2502f98d0cc87553 280 PRINTS PR00996 Glutamate methyltransferase family signature 137 153 3.0E-40 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Astex_0612 98dac63d204f41db2502f98d0cc87553 280 PRINTS PR00996 Glutamate methyltransferase family signature 224 247 3.0E-40 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Astex_0612 98dac63d204f41db2502f98d0cc87553 280 PRINTS PR00996 Glutamate methyltransferase family signature 205 219 3.0E-40 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Astex_0612 98dac63d204f41db2502f98d0cc87553 280 PRINTS PR00996 Glutamate methyltransferase family signature 25 38 3.0E-40 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 Astex_2386 9955437da95bd7bb14e0301c9714eb0b 1075 Hamap MF_01902 Error-prone DNA polymerase [dnaE2]. 5 1075 13.203 T 13-10-2018 IPR023073 DNA polymerase, error-prone GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Astex_2386 9955437da95bd7bb14e0301c9714eb0b 1075 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 274 697 3.7E-144 T 13-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Astex_2386 9955437da95bd7bb14e0301c9714eb0b 1075 Pfam PF02811 PHP domain 8 122 2.7E-9 T 13-10-2018 IPR004013 PHP domain GO:0003824 Astex_2386 9955437da95bd7bb14e0301c9714eb0b 1075 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 5 984 2.6E-162 T 13-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Astex_2386 9955437da95bd7bb14e0301c9714eb0b 1075 Gene3D G3DSA:3.20.20.140 1 251 3.1E-60 T 13-10-2018 Astex_2386 9955437da95bd7bb14e0301c9714eb0b 1075 SUPERFAMILY SSF89550 13 236 3.34E-9 T 13-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 Astex_2386 9955437da95bd7bb14e0301c9714eb0b 1075 SMART SM00481 6 73 7.0E-13 T 13-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal Astex_2386 9955437da95bd7bb14e0301c9714eb0b 1075 Pfam PF14579 Helix-hairpin-helix motif 770 862 1.7E-21 T 13-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Astex_1894 02da50813c1601c3888714f5167c010e 507 SUPERFAMILY SSF51905 6 408 4.37E-30 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_1894 02da50813c1601c3888714f5167c010e 507 Gene3D G3DSA:3.50.50.60 1 496 5.9E-181 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_1894 02da50813c1601c3888714f5167c010e 507 Pfam PF04820 Tryptophan halogenase 7 463 4.8E-171 T 13-10-2018 IPR006905 Flavin-dependent halogenase Astex_1894 02da50813c1601c3888714f5167c010e 507 PIRSF PIRSF011396 1 501 1.8E-183 T 13-10-2018 IPR033856 Flavin-dependent tryptophan halogenase Astex_0474 e2d214a6584c134da552871827960019 128 Gene3D G3DSA:3.30.300.20 4 128 4.2E-30 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta Astex_0474 e2d214a6584c134da552871827960019 128 Pfam PF02566 OsmC-like protein 34 125 9.9E-17 T 13-10-2018 IPR003718 OsmC/Ohr family Astex_0474 e2d214a6584c134da552871827960019 128 SUPERFAMILY SSF82784 8 127 9.55E-34 T 13-10-2018 IPR036102 OsmC/Ohr superfamily Astex_0791 9be68fd3d2c69bdaa6585bac49d547b0 568 Gene3D G3DSA:2.60.40.380 31 130 2.5E-28 T 13-10-2018 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 Astex_0791 9be68fd3d2c69bdaa6585bac49d547b0 568 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 40 127 2.1E-26 T 13-10-2018 IPR032093 Phospholipase D, N-terminal Astex_0791 9be68fd3d2c69bdaa6585bac49d547b0 568 Pfam PF09423 PhoD-like phosphatase 137 531 5.5E-115 T 13-10-2018 IPR018946 Alkaline phosphatase D-related Astex_0791 9be68fd3d2c69bdaa6585bac49d547b0 568 SUPERFAMILY SSF56300 137 531 8.06E-26 T 13-10-2018 Astex_3768 cb3d0d34b8f954754dc39982ba1a67ce 309 Pfam PF10686 Protein of unknown function (DUF2493) 177 239 4.2E-12 T 13-10-2018 IPR019627 Mycobacteriophage D29, Gp61 Astex_0165 a365f1e5c542aba13e36325787e22a75 466 SUPERFAMILY SSF51126 47 420 3.46E-72 T 13-10-2018 IPR011050 Pectin lyase fold/virulence factor Astex_0165 a365f1e5c542aba13e36325787e22a75 466 Pfam PF00295 Glycosyl hydrolases family 28 206 400 1.7E-20 T 13-10-2018 IPR000743 Glycoside hydrolase, family 28 GO:0004650|GO:0005975 Astex_0165 a365f1e5c542aba13e36325787e22a75 466 Gene3D G3DSA:2.160.20.10 40 464 1.5E-108 T 13-10-2018 IPR012334 Pectin lyase fold Astex_3386 d6ae44046f39fcd684f981f55c26202f 334 Pfam PF13621 Cupin-like domain 18 254 1.7E-47 T 13-10-2018 Astex_3386 d6ae44046f39fcd684f981f55c26202f 334 Gene3D G3DSA:2.60.120.650 2 259 4.0E-40 T 13-10-2018 Astex_3386 d6ae44046f39fcd684f981f55c26202f 334 SMART SM00558 117 270 8.8E-5 T 13-10-2018 IPR003347 JmjC domain Astex_3386 d6ae44046f39fcd684f981f55c26202f 334 SUPERFAMILY SSF51197 6 259 2.61E-38 T 13-10-2018 Astex_1671 dbc9323bab5692ba2ef59ee993b43b9a 297 TIGRFAM TIGR00325 lpxC: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 7 289 1.5E-96 T 13-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 Astex_1671 dbc9323bab5692ba2ef59ee993b43b9a 297 Gene3D G3DSA:3.30.1700.10 133 295 3.5E-60 T 13-10-2018 IPR011334 UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 Astex_1671 dbc9323bab5692ba2ef59ee993b43b9a 297 SUPERFAMILY SSF54211 138 280 8.34E-49 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Astex_1671 dbc9323bab5692ba2ef59ee993b43b9a 297 SUPERFAMILY SSF54211 6 130 3.03E-37 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold Astex_1671 dbc9323bab5692ba2ef59ee993b43b9a 297 Gene3D G3DSA:3.30.230.20 5 132 5.8E-45 T 13-10-2018 IPR015870 UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 Astex_1671 dbc9323bab5692ba2ef59ee993b43b9a 297 Pfam PF03331 UDP-3-O-acyl N-acetylglycosamine deacetylase 8 278 4.7E-103 T 13-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 Astex_1671 dbc9323bab5692ba2ef59ee993b43b9a 297 Hamap MF_00388 UDP-3-O-acyl-N-acetylglucosamine deacetylase [lpxC]. 5 282 43.475 T 13-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 Astex_1559 9ddefecb96e2272dadf45fc7ba45674c 172 SUPERFAMILY SSF48295 43 117 3.24E-15 T 13-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 Astex_1559 9ddefecb96e2272dadf45fc7ba45674c 172 SUPERFAMILY SSF46689 1 51 5.73E-9 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Astex_1559 9ddefecb96e2272dadf45fc7ba45674c 172 Pfam PF13518 Helix-turn-helix domain 63 117 7.7E-13 T 13-10-2018 Astex_1559 9ddefecb96e2272dadf45fc7ba45674c 172 Pfam PF01527 Transposase 3 48 4.1E-7 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 Astex_0372 9ddefecb96e2272dadf45fc7ba45674c 172 SUPERFAMILY SSF48295 43 117 3.24E-15 T 13-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 Astex_0372 9ddefecb96e2272dadf45fc7ba45674c 172 SUPERFAMILY SSF46689 1 51 5.73E-9 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Astex_0372 9ddefecb96e2272dadf45fc7ba45674c 172 Pfam PF13518 Helix-turn-helix domain 63 117 7.7E-13 T 13-10-2018 Astex_0372 9ddefecb96e2272dadf45fc7ba45674c 172 Pfam PF01527 Transposase 3 48 4.1E-7 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 Astex_0955 9c413120d616f3ab1966e047f55b2d4d 122 SUPERFAMILY SSF50193 1 122 9.16E-53 T 13-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 Astex_0955 9c413120d616f3ab1966e047f55b2d4d 122 SMART SM01374 1 122 5.6E-86 T 13-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 Astex_0955 9c413120d616f3ab1966e047f55b2d4d 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 6.8E-58 T 13-10-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 Astex_0955 9c413120d616f3ab1966e047f55b2d4d 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 3.6E-56 T 13-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 Astex_0955 9c413120d616f3ab1966e047f55b2d4d 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 27.82 T 13-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 Astex_0955 9c413120d616f3ab1966e047f55b2d4d 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 13-10-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0955 9c413120d616f3ab1966e047f55b2d4d 122 Gene3D G3DSA:2.40.150.20 1 122 2.1E-55 T 13-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 Astex_3298 7b0ec502897008668b2135935c1d5ea0 121 SUPERFAMILY SSF50022 13 120 1.26E-20 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 Astex_3298 7b0ec502897008668b2135935c1d5ea0 121 Gene3D G3DSA:2.102.10.10 15 121 3.7E-15 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 Astex_3298 7b0ec502897008668b2135935c1d5ea0 121 Pfam PF00355 Rieske [2Fe-2S] domain 43 103 3.0E-10 T 13-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Astex_1865 81ab8d60ceee5d4196f511859babe723 308 Pfam PF02219 Methylenetetrahydrofolate reductase 20 299 3.1E-90 T 13-10-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 Astex_1865 81ab8d60ceee5d4196f511859babe723 308 SUPERFAMILY SSF51730 21 300 1.35E-92 T 13-10-2018 IPR029041 FAD-linked oxidoreductase-like Astex_1865 81ab8d60ceee5d4196f511859babe723 308 Gene3D G3DSA:3.20.20.220 6 307 4.4E-98 T 13-10-2018 Astex_1865 81ab8d60ceee5d4196f511859babe723 308 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 25 298 2.4E-98 T 13-10-2018 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 Astex_1208 bbaba718a0abcdca5f373fc905c0ae00 327 PIRSF PIRSF002849 2 327 1.9E-121 T 13-10-2018 Astex_1208 bbaba718a0abcdca5f373fc905c0ae00 327 Gene3D G3DSA:1.10.8.300 212 325 1.7E-32 T 13-10-2018 Astex_1208 bbaba718a0abcdca5f373fc905c0ae00 327 SUPERFAMILY SSF52540 13 301 4.82E-45 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1208 bbaba718a0abcdca5f373fc905c0ae00 327 Gene3D G3DSA:3.40.50.300 5 211 1.8E-50 T 13-10-2018 Astex_1208 bbaba718a0abcdca5f373fc905c0ae00 327 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 45 179 4.9E-63 T 13-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 Astex_0555 a53526126a9a006eb3031efbc18af4cb 125 Gene3D G3DSA:3.40.50.2300 2 125 3.4E-26 T 13-10-2018 Astex_0555 a53526126a9a006eb3031efbc18af4cb 125 SMART SM00448 4 114 1.9E-18 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_0555 a53526126a9a006eb3031efbc18af4cb 125 SUPERFAMILY SSF52172 3 119 4.27E-26 T 13-10-2018 IPR011006 CheY-like superfamily Astex_0555 a53526126a9a006eb3031efbc18af4cb 125 Pfam PF00072 Response regulator receiver domain 6 114 1.3E-20 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1946 f94266b5166c7956f758d144205da987 284 SUPERFAMILY SSF52317 30 281 3.89E-29 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Astex_1946 f94266b5166c7956f758d144205da987 284 Gene3D G3DSA:3.40.50.880 27 283 6.5E-41 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Astex_1946 f94266b5166c7956f758d144205da987 284 Pfam PF06283 Trehalose utilisation 32 267 2.6E-18 T 13-10-2018 IPR029010 ThuA-like domain Astex_1457 b607f475c323d3cb51e433b38b6792ce 76 SUPERFAMILY SSF82057 3 76 3.48E-24 T 13-10-2018 Astex_1457 b607f475c323d3cb51e433b38b6792ce 76 Gene3D G3DSA:2.30.30.40 5 76 2.4E-31 T 13-10-2018 Astex_1457 b607f475c323d3cb51e433b38b6792ce 76 Pfam PF03831 PhnA domain 8 76 1.2E-28 T 13-10-2018 IPR013988 PhnA protein, C-terminal Astex_0818 b7de80f3454dcc34e01a3d077db3316b 295 Pfam PF08029 HisG, C-terminal domain 221 292 4.5E-26 T 13-10-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 Astex_0818 b7de80f3454dcc34e01a3d077db3316b 295 Pfam PF01634 ATP phosphoribosyltransferase 55 211 3.6E-45 T 13-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 Astex_0818 b7de80f3454dcc34e01a3d077db3316b 295 Gene3D G3DSA:3.40.190.10 8 216 2.2E-65 T 13-10-2018 Astex_0818 b7de80f3454dcc34e01a3d077db3316b 295 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 7 295 32.773 T 13-10-2018 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 Astex_0818 b7de80f3454dcc34e01a3d077db3316b 295 Gene3D G3DSA:3.30.70.120 222 295 3.8E-34 T 13-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal Astex_0818 b7de80f3454dcc34e01a3d077db3316b 295 SUPERFAMILY SSF53850 7 217 5.43E-60 T 13-10-2018 Astex_0818 b7de80f3454dcc34e01a3d077db3316b 295 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 8 192 4.2E-52 T 13-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 Astex_0818 b7de80f3454dcc34e01a3d077db3316b 295 Gene3D G3DSA:3.40.190.10 99 188 2.2E-65 T 13-10-2018 Astex_0818 b7de80f3454dcc34e01a3d077db3316b 295 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 203 294 3.4E-30 T 13-10-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 Astex_0818 b7de80f3454dcc34e01a3d077db3316b 295 SUPERFAMILY SSF54913 223 294 8.0E-23 T 13-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta Astex_0206 e196fd1bd76b051fa5fd94fb25825dc9 142 SUPERFAMILY SSF54197 12 139 1.0E-25 T 13-10-2018 IPR036265 HIT-like superfamily Astex_0206 e196fd1bd76b051fa5fd94fb25825dc9 142 Pfam PF01230 HIT domain 11 104 7.9E-14 T 13-10-2018 IPR001310 Histidine triad (HIT) protein Astex_0206 e196fd1bd76b051fa5fd94fb25825dc9 142 Gene3D G3DSA:3.30.428.10 1 140 2.7E-34 T 13-10-2018 IPR036265 HIT-like superfamily Astex_0206 e196fd1bd76b051fa5fd94fb25825dc9 142 PIRSF PIRSF000714 3 142 1.5E-43 T 13-10-2018 IPR026026 Histidine triad hydrolase, Hint-type Astex_2374 03d8f80aaba0d881a8d0af87946f2d87 220 Pfam PF01738 Dienelactone hydrolase family 25 217 2.5E-50 T 13-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 Astex_2374 03d8f80aaba0d881a8d0af87946f2d87 220 Gene3D G3DSA:3.40.50.1820 2 217 1.5E-46 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_2374 03d8f80aaba0d881a8d0af87946f2d87 220 SUPERFAMILY SSF53474 2 220 4.05E-37 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_3073 311d61056f68d9bdd21d13b0aac23b63 76 PIRSF PIRSF003113 1 76 4.8E-18 T 13-10-2018 IPR002634 BolA protein Astex_3073 311d61056f68d9bdd21d13b0aac23b63 76 Pfam PF01722 BolA-like protein 27 75 1.8E-12 T 13-10-2018 IPR002634 BolA protein Astex_3073 311d61056f68d9bdd21d13b0aac23b63 76 Gene3D G3DSA:3.30.300.90 3 76 2.6E-26 T 13-10-2018 Astex_3073 311d61056f68d9bdd21d13b0aac23b63 76 SUPERFAMILY SSF82657 3 74 4.97E-21 T 13-10-2018 IPR036065 BolA-like superfamily Astex_2035 1ba444ec9215283062a81402db3692bd 345 SUPERFAMILY SSF53223 2 136 2.65E-40 T 13-10-2018 Astex_2035 1ba444ec9215283062a81402db3692bd 345 PIRSF PIRSF000188 1 345 7.3E-129 T 13-10-2018 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 Astex_2035 1ba444ec9215283062a81402db3692bd 345 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 220 300 6.9E-8 T 13-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Astex_2035 1ba444ec9215283062a81402db3692bd 345 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 284 295 5.0E-15 T 13-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Astex_2035 1ba444ec9215283062a81402db3692bd 345 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 64 78 5.0E-15 T 13-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Astex_2035 1ba444ec9215283062a81402db3692bd 345 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 174 194 5.0E-15 T 13-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Astex_2035 1ba444ec9215283062a81402db3692bd 345 SUPERFAMILY SSF51735 142 344 3.84E-43 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_2035 1ba444ec9215283062a81402db3692bd 345 SMART SM00839 142 345 6.6E-55 T 13-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Astex_2035 1ba444ec9215283062a81402db3692bd 345 Gene3D G3DSA:3.40.50.720 132 335 1.7E-122 T 13-10-2018 Astex_2035 1ba444ec9215283062a81402db3692bd 345 Gene3D G3DSA:3.40.50.10860 9 342 1.7E-122 T 13-10-2018 Astex_2035 1ba444ec9215283062a81402db3692bd 345 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 10 129 1.2E-23 T 13-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 Astex_1518 0f7b45e5c115bc2cae91ea48f4434efc 614 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 13 299 3.9E-77 T 13-10-2018 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 Astex_1518 0f7b45e5c115bc2cae91ea48f4434efc 614 SUPERFAMILY SSF51735 416 546 8.64E-33 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_1518 0f7b45e5c115bc2cae91ea48f4434efc 614 Gene3D G3DSA:1.20.1530.20 2 396 6.2E-81 T 13-10-2018 IPR038770 Sodium/solute symporter superfamily Astex_1518 0f7b45e5c115bc2cae91ea48f4434efc 614 PRINTS PR00335 TrkA potassium uptake protein signature 475 485 8.0E-7 T 13-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 Astex_1518 0f7b45e5c115bc2cae91ea48f4434efc 614 PRINTS PR00335 TrkA potassium uptake protein signature 417 431 8.0E-7 T 13-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 Astex_1518 0f7b45e5c115bc2cae91ea48f4434efc 614 PRINTS PR00335 TrkA potassium uptake protein signature 464 474 8.0E-7 T 13-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 Astex_1518 0f7b45e5c115bc2cae91ea48f4434efc 614 PRINTS PR00335 TrkA potassium uptake protein signature 434 448 8.0E-7 T 13-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 Astex_1518 0f7b45e5c115bc2cae91ea48f4434efc 614 Pfam PF00999 Sodium/hydrogen exchanger family 11 389 7.5E-61 T 13-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 Astex_1518 0f7b45e5c115bc2cae91ea48f4434efc 614 Pfam PF02254 TrkA-N domain 418 530 8.5E-26 T 13-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 Astex_1518 0f7b45e5c115bc2cae91ea48f4434efc 614 Gene3D G3DSA:3.40.50.720 413 576 2.9E-37 T 13-10-2018 Astex_1464 821004a05e8ab05a3e8f4153b7885572 524 SUPERFAMILY SSF103473 16 443 3.79E-65 T 13-10-2018 IPR036259 MFS transporter superfamily Astex_1464 821004a05e8ab05a3e8f4153b7885572 524 Pfam PF07690 Major Facilitator Superfamily 25 418 3.3E-52 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Astex_1464 821004a05e8ab05a3e8f4153b7885572 524 Gene3D G3DSA:1.20.1250.20 268 447 2.3E-17 T 13-10-2018 Astex_1464 821004a05e8ab05a3e8f4153b7885572 524 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 21 509 1.6E-139 T 13-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 Astex_1464 821004a05e8ab05a3e8f4153b7885572 524 Gene3D G3DSA:1.20.1720.10 22 228 9.1E-47 T 13-10-2018 Astex_0985 9a7c537457d738b3f61e09e47abe4f7f 162 ProSitePatterns PS01320 Uncharacterized protein family UPF0067 signature. 101 118 - T 13-10-2018 IPR000614 Free Met sulfoxide reductase conserved site Astex_0985 9a7c537457d738b3f61e09e47abe4f7f 162 Gene3D G3DSA:3.30.450.40 5 161 9.3E-53 T 13-10-2018 IPR029016 GAF-like domain superfamily Astex_0985 9a7c537457d738b3f61e09e47abe4f7f 162 SUPERFAMILY SSF55781 2 155 1.92E-33 T 13-10-2018 Astex_0985 9a7c537457d738b3f61e09e47abe4f7f 162 Pfam PF13185 GAF domain 50 156 8.0E-9 T 13-10-2018 IPR003018 GAF domain GO:0005515 Astex_2231 ba1b90dcaa30715966425466993d61f9 671 SUPERFAMILY SSF53474 387 663 6.15E-18 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_2231 ba1b90dcaa30715966425466993d61f9 671 Gene3D G3DSA:3.40.50.1820 419 661 9.2E-18 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_2231 ba1b90dcaa30715966425466993d61f9 671 Pfam PF00326 Prolyl oligopeptidase family 496 567 3.1E-5 T 13-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 Astex_3191 15fe4911150ed4a3916e1fcb3c820eac 431 Gene3D G3DSA:2.30.40.10 13 428 7.7E-110 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Astex_3191 15fe4911150ed4a3916e1fcb3c820eac 431 SUPERFAMILY SSF51556 63 374 6.24E-83 T 13-10-2018 IPR032466 Metal-dependent hydrolase Astex_3191 15fe4911150ed4a3916e1fcb3c820eac 431 Gene3D G3DSA:3.20.20.140 64 375 7.7E-110 T 13-10-2018 Astex_3191 15fe4911150ed4a3916e1fcb3c820eac 431 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 46 430 9.3E-92 T 13-10-2018 Astex_3191 15fe4911150ed4a3916e1fcb3c820eac 431 Pfam PF01979 Amidohydrolase family 290 428 7.7E-14 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 Astex_3191 15fe4911150ed4a3916e1fcb3c820eac 431 SUPERFAMILY SSF51338 7 430 8.65E-24 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Astex_1279 a705f5718bad77581741d19317a7bd99 241 Gene3D G3DSA:1.10.357.10 115 240 1.0E-16 T 13-10-2018 Astex_1279 a705f5718bad77581741d19317a7bd99 241 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 76 99 1.6E-5 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Astex_1279 a705f5718bad77581741d19317a7bd99 241 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 55 68 1.6E-5 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Astex_1279 a705f5718bad77581741d19317a7bd99 241 SUPERFAMILY SSF46689 42 116 3.64E-16 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Astex_1279 a705f5718bad77581741d19317a7bd99 241 SUPERFAMILY SSF48498 130 238 8.56E-14 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily Astex_1279 a705f5718bad77581741d19317a7bd99 241 Gene3D G3DSA:1.10.10.60 40 108 2.3E-25 T 13-10-2018 Astex_1279 a705f5718bad77581741d19317a7bd99 241 Pfam PF00440 Bacterial regulatory proteins, tetR family 56 99 8.4E-13 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Astex_0599 c473f2e58a16ae15675d539f9cdbc5a3 700 Pfam PF00771 FHIPEP family 37 692 3.6E-251 T 13-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 Astex_0599 c473f2e58a16ae15675d539f9cdbc5a3 700 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 44 57 1.9E-54 T 13-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 Astex_0599 c473f2e58a16ae15675d539f9cdbc5a3 700 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 148 164 1.9E-54 T 13-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 Astex_0599 c473f2e58a16ae15675d539f9cdbc5a3 700 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 167 185 1.9E-54 T 13-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 Astex_0599 c473f2e58a16ae15675d539f9cdbc5a3 700 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 197 214 1.9E-54 T 13-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 Astex_0599 c473f2e58a16ae15675d539f9cdbc5a3 700 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 81 100 1.9E-54 T 13-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 Astex_0599 c473f2e58a16ae15675d539f9cdbc5a3 700 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 248 262 1.9E-54 T 13-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 Astex_0599 c473f2e58a16ae15675d539f9cdbc5a3 700 PIRSF PIRSF005419 15 700 1.3E-224 T 13-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 Astex_0599 c473f2e58a16ae15675d539f9cdbc5a3 700 Gene3D G3DSA:1.10.490.80 602 700 4.0E-13 T 13-10-2018 Astex_0599 c473f2e58a16ae15675d539f9cdbc5a3 700 Gene3D G3DSA:3.40.30.60 368 510 4.9E-45 T 13-10-2018 Astex_0599 c473f2e58a16ae15675d539f9cdbc5a3 700 Gene3D G3DSA:1.10.8.540 511 599 8.5E-24 T 13-10-2018 Astex_0599 c473f2e58a16ae15675d539f9cdbc5a3 700 TIGRFAM TIGR01398 FlhA: flagellar biosynthesis protein FlhA 27 700 6.7E-273 T 13-10-2018 IPR006301 Flagellar biosynthesis protein FlhA GO:0016021|GO:0044780 Astex_0599 c473f2e58a16ae15675d539f9cdbc5a3 700 ProSitePatterns PS00994 Bacterial export FHIPEP family signature. 153 176 - T 13-10-2018 IPR025505 FHIPEP conserved site Astex_0756 b0a2529edb94b81b91c3e1185c80b290 411 SMART SM00729 121 341 0.0017 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Astex_0756 b0a2529edb94b81b91c3e1185c80b290 411 PIRSF PIRSF006004 12 381 1.0E-143 T 13-10-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 Astex_0756 b0a2529edb94b81b91c3e1185c80b290 411 SUPERFAMILY SSF102114 117 340 1.27E-18 T 13-10-2018 Astex_0756 b0a2529edb94b81b91c3e1185c80b290 411 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 16 369 71.618 T 13-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 Astex_0756 b0a2529edb94b81b91c3e1185c80b290 411 Gene3D G3DSA:1.10.150.530 4 81 8.6E-13 T 13-10-2018 Astex_0756 b0a2529edb94b81b91c3e1185c80b290 411 Pfam PF04055 Radical SAM superfamily 126 298 9.5E-23 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Astex_0756 b0a2529edb94b81b91c3e1185c80b290 411 Gene3D G3DSA:3.20.20.70 83 354 2.1E-105 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_0756 b0a2529edb94b81b91c3e1185c80b290 411 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 13 368 1.6E-119 T 13-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 Astex_1683 a046bd24aaf7e8e439e6a2775219ad93 234 Pfam PF01618 MotA/TolQ/ExbB proton channel family 113 213 1.8E-34 T 13-10-2018 IPR002898 MotA/TolQ/ExbB proton channel Astex_3596 ebab06daf3573dc2cb145160a323ec43 476 SMART SM00710 339 360 2600.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat Astex_3596 ebab06daf3573dc2cb145160a323ec43 476 SMART SM00710 309 331 380.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat Astex_3596 ebab06daf3573dc2cb145160a323ec43 476 SMART SM00710 398 419 3100.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat Astex_3596 ebab06daf3573dc2cb145160a323ec43 476 SMART SM00710 248 280 3100.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat Astex_3596 ebab06daf3573dc2cb145160a323ec43 476 SMART SM00710 282 303 41.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat Astex_3596 ebab06daf3573dc2cb145160a323ec43 476 SMART SM00710 219 247 6.2 T 13-10-2018 IPR006626 Parallel beta-helix repeat Astex_3596 ebab06daf3573dc2cb145160a323ec43 476 SUPERFAMILY SSF51126 32 449 4.09E-75 T 13-10-2018 IPR011050 Pectin lyase fold/virulence factor Astex_3596 ebab06daf3573dc2cb145160a323ec43 476 Gene3D G3DSA:2.160.20.10 19 470 5.7E-102 T 13-10-2018 IPR012334 Pectin lyase fold Astex_3596 ebab06daf3573dc2cb145160a323ec43 476 Pfam PF00295 Glycosyl hydrolases family 28 82 363 1.1E-18 T 13-10-2018 IPR000743 Glycoside hydrolase, family 28 GO:0004650|GO:0005975 Astex_0197 0d9dd93e85c986d4a59cbcc5bde158fc 221 Gene3D G3DSA:2.50.20.10 48 221 1.0E-25 T 13-10-2018 Astex_0197 0d9dd93e85c986d4a59cbcc5bde158fc 221 SUPERFAMILY SSF89392 49 220 1.96E-25 T 13-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX Astex_0197 0d9dd93e85c986d4a59cbcc5bde158fc 221 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 63 213 1.3E-30 T 13-10-2018 IPR004564 Outer membrane lipoprotein carrier protein LolA-like Astex_2395 4f16ebc25f3ecd3b9e9bb2b5f8bba109 827 Pfam PF07715 TonB-dependent Receptor Plug Domain 132 240 9.9E-17 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_2395 4f16ebc25f3ecd3b9e9bb2b5f8bba109 827 Pfam PF00593 TonB dependent receptor 364 826 3.5E-38 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_2395 4f16ebc25f3ecd3b9e9bb2b5f8bba109 827 Gene3D G3DSA:3.55.50.30 32 117 1.4E-21 T 13-10-2018 Astex_2395 4f16ebc25f3ecd3b9e9bb2b5f8bba109 827 Gene3D G3DSA:2.40.170.20 123 827 4.1E-122 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_2395 4f16ebc25f3ecd3b9e9bb2b5f8bba109 827 SMART SM00965 56 109 2.5E-7 T 13-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 Astex_2395 4f16ebc25f3ecd3b9e9bb2b5f8bba109 827 SUPERFAMILY SSF56935 114 827 4.03E-111 T 13-10-2018 Astex_3352 9bcab9c7690c6419dfe479ceb8a0b65d 275 Gene3D G3DSA:2.60.120.200 30 275 1.3E-77 T 13-10-2018 Astex_3352 9bcab9c7690c6419dfe479ceb8a0b65d 275 SUPERFAMILY SSF49899 31 274 2.08E-67 T 13-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily Astex_3352 9bcab9c7690c6419dfe479ceb8a0b65d 275 Pfam PF00722 Glycosyl hydrolases family 16 68 269 3.6E-33 T 13-10-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 Astex_3808 fb8ad392827b0e2aefe0017163ac181b 775 Pfam PF14072 DNA-sulfur modification-associated 66 301 5.1E-15 T 13-10-2018 IPR017642 DNA sulphur modification protein DndB Astex_1019 57539fe8ed914e0a581dd00bb4285d6d 255 SUPERFAMILY SSF46785 1 62 4.67E-10 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_1019 57539fe8ed914e0a581dd00bb4285d6d 255 Pfam PF08279 HTH domain 6 59 3.4E-14 T 13-10-2018 IPR013196 Helix-turn-helix, type 11 Astex_1019 57539fe8ed914e0a581dd00bb4285d6d 255 Pfam PF13280 WYL domain 140 224 5.1E-11 T 13-10-2018 IPR026881 WYL domain Astex_1019 57539fe8ed914e0a581dd00bb4285d6d 255 Gene3D G3DSA:1.10.10.10 1 63 1.8E-15 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_3295 8e96fe9ab2e93ef5b5c270ffd93cae31 353 SUPERFAMILY SSF54593 4 336 2.13E-75 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Astex_3295 8e96fe9ab2e93ef5b5c270ffd93cae31 353 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 158 268 6.7E-15 T 13-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Astex_3295 8e96fe9ab2e93ef5b5c270ffd93cae31 353 Gene3D G3DSA:3.10.180.10 4 150 9.7E-32 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Astex_3295 8e96fe9ab2e93ef5b5c270ffd93cae31 353 Pfam PF14696 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal 7 128 1.0E-37 T 13-10-2018 Astex_3295 8e96fe9ab2e93ef5b5c270ffd93cae31 353 Gene3D G3DSA:3.10.180.10 153 350 1.1E-66 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Astex_3295 8e96fe9ab2e93ef5b5c270ffd93cae31 353 PIRSF PIRSF009283 1 350 1.6E-112 T 13-10-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 Astex_3295 8e96fe9ab2e93ef5b5c270ffd93cae31 353 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 13 348 9.7E-117 T 13-10-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 Astex_3836 5732f69ab2835c76646d032446730aea 191 Pfam PF04542 Sigma-70 region 2 27 92 2.5E-18 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 Astex_3836 5732f69ab2835c76646d032446730aea 191 SUPERFAMILY SSF88946 5 102 4.08E-28 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 Astex_3836 5732f69ab2835c76646d032446730aea 191 Gene3D G3DSA:1.10.1740.10 4 93 4.3E-28 T 13-10-2018 Astex_3836 5732f69ab2835c76646d032446730aea 191 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 23 186 1.1E-28 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 Astex_3836 5732f69ab2835c76646d032446730aea 191 Gene3D G3DSA:1.10.10.10 101 188 2.9E-14 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_3836 5732f69ab2835c76646d032446730aea 191 Pfam PF08281 Sigma-70, region 4 130 182 3.6E-11 T 13-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Astex_3836 5732f69ab2835c76646d032446730aea 191 SUPERFAMILY SSF88659 125 187 1.0E-11 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Astex_3300 ab4112de6110528facc5ffc7cf22dbda 116 Gene3D G3DSA:3.30.70.100 2 103 5.4E-6 T 13-10-2018 Astex_3300 ab4112de6110528facc5ffc7cf22dbda 116 Pfam PF05336 L-rhamnose mutarotase 4 112 1.7E-24 T 13-10-2018 IPR008000 Rhamnose/fucose mutarotase GO:0005737|GO:0016857 Astex_3300 ab4112de6110528facc5ffc7cf22dbda 116 SUPERFAMILY SSF54909 3 112 4.72E-21 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel Astex_3108 df2448a4ac061993a1fb28840bf66719 272 Pfam PF00669 Bacterial flagellin N-terminal helical region 6 139 3.3E-22 T 13-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 Astex_3108 df2448a4ac061993a1fb28840bf66719 272 Gene3D G3DSA:2.30.220.10 192 212 2.1E-21 T 13-10-2018 Astex_3108 df2448a4ac061993a1fb28840bf66719 272 Gene3D G3DSA:2.170.280.10 178 191 2.1E-21 T 13-10-2018 Astex_3108 df2448a4ac061993a1fb28840bf66719 272 Gene3D G3DSA:1.20.58.1830 6 34 2.1E-21 T 13-10-2018 Astex_3108 df2448a4ac061993a1fb28840bf66719 272 Pfam PF00700 Bacterial flagellin C-terminal helical region 189 271 7.8E-14 T 13-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 Astex_3108 df2448a4ac061993a1fb28840bf66719 272 SUPERFAMILY SSF64518 5 272 1.57E-52 T 13-10-2018 Astex_3108 df2448a4ac061993a1fb28840bf66719 272 Gene3D G3DSA:1.20.1330.10 46 177 2.1E-21 T 13-10-2018 Astex_3108 df2448a4ac061993a1fb28840bf66719 272 Gene3D G3DSA:1.10.8.410 227 272 1.5E-6 T 13-10-2018 Astex_1381 83f75db9f95db2d486613e617d1b5cd6 391 Pfam PF13088 BNR repeat-like domain 69 357 5.5E-49 T 13-10-2018 IPR011040 Sialidase KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 Astex_1381 83f75db9f95db2d486613e617d1b5cd6 391 SUPERFAMILY SSF50939 64 376 1.11E-21 T 13-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 Astex_1381 83f75db9f95db2d486613e617d1b5cd6 391 Gene3D G3DSA:2.120.10.10 42 371 8.2E-12 T 13-10-2018 Astex_3412 f05d7551e08e11f2ebe4e6680f2b4368 432 Gene3D G3DSA:1.10.287.470 117 244 1.0E-39 T 13-10-2018 Astex_3412 f05d7551e08e11f2ebe4e6680f2b4368 432 Gene3D G3DSA:2.40.50.100 83 279 1.0E-39 T 13-10-2018 Astex_3412 f05d7551e08e11f2ebe4e6680f2b4368 432 Gene3D G3DSA:2.40.420.20 352 411 1.0E-39 T 13-10-2018 Astex_3412 f05d7551e08e11f2ebe4e6680f2b4368 432 Pfam PF13437 HlyD family secretion protein 244 335 5.7E-9 T 13-10-2018 Astex_3412 f05d7551e08e11f2ebe4e6680f2b4368 432 Gene3D G3DSA:2.40.30.170 72 351 1.0E-39 T 13-10-2018 Astex_3412 f05d7551e08e11f2ebe4e6680f2b4368 432 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 191 422 1.6E-30 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 Astex_3412 f05d7551e08e11f2ebe4e6680f2b4368 432 Pfam PF13533 Biotin-lipoyl like 85 131 2.1E-7 T 13-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain Astex_0870 c9611cccbcdb01c162dc6d99704275d9 269 Pfam PF10670 Domain of unknown function (DUF4198) 27 245 1.7E-36 T 13-10-2018 IPR019613 Protein of unknown function DUF4198 Astex_3565 ab29673082d9959051c1254eecddb88d 322 Gene3D G3DSA:3.40.50.720 99 290 6.9E-109 T 13-10-2018 Astex_3565 ab29673082d9959051c1254eecddb88d 322 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 111 290 1.8E-54 T 13-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 Astex_3565 ab29673082d9959051c1254eecddb88d 322 SUPERFAMILY SSF52283 3 138 9.83E-33 T 13-10-2018 Astex_3565 ab29673082d9959051c1254eecddb88d 322 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 230 246 - T 13-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site Astex_3565 ab29673082d9959051c1254eecddb88d 322 Gene3D G3DSA:3.40.50.720 5 315 6.9E-109 T 13-10-2018 Astex_3565 ab29673082d9959051c1254eecddb88d 322 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 6 320 1.1E-29 T 13-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 Astex_3565 ab29673082d9959051c1254eecddb88d 322 SUPERFAMILY SSF51735 102 291 2.57E-57 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_0268 64f2cbd9c2516779417af31009016d1c 443 TIGRFAM TIGR01579 MiaB-like-C: MiaB-like tRNA modifying enzyme 30 398 2.5E-123 T 13-10-2018 IPR006467 MiaB-like tRNA modifying enzyme GO:0016740 Astex_0268 64f2cbd9c2516779417af31009016d1c 443 Pfam PF04055 Radical SAM superfamily 159 331 1.3E-19 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Astex_0268 64f2cbd9c2516779417af31009016d1c 443 SUPERFAMILY SSF102114 133 377 1.16E-51 T 13-10-2018 Astex_0268 64f2cbd9c2516779417af31009016d1c 443 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 27 398 6.3E-97 T 13-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 Astex_0268 64f2cbd9c2516779417af31009016d1c 443 SMART SM00729 155 374 1.3E-49 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Astex_0268 64f2cbd9c2516779417af31009016d1c 443 Pfam PF00919 Uncharacterized protein family UPF0004 27 113 5.3E-15 T 13-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 Astex_0268 64f2cbd9c2516779417af31009016d1c 443 Gene3D G3DSA:3.80.30.20 152 386 2.3E-68 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe Astex_0268 64f2cbd9c2516779417af31009016d1c 443 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 159 179 - T 13-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 Astex_0268 64f2cbd9c2516779417af31009016d1c 443 Gene3D G3DSA:3.40.50.12160 26 138 2.8E-14 T 13-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily Astex_0932 0b2866c1abbc33a172b10faffffcde5b 250 Gene3D G3DSA:3.40.50.880 4 249 4.4E-56 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Astex_0932 0b2866c1abbc33a172b10faffffcde5b 250 Pfam PF07722 Peptidase C26 6 225 4.4E-58 T 13-10-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 Astex_0932 0b2866c1abbc33a172b10faffffcde5b 250 SUPERFAMILY SSF52317 6 245 6.46E-35 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Astex_1014 8cf459e069ff8dbb2d8388a874ad720b 427 SUPERFAMILY SSF51905 32 332 1.42E-43 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_1014 8cf459e069ff8dbb2d8388a874ad720b 427 Pfam PF01266 FAD dependent oxidoreductase 34 383 1.6E-55 T 13-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 Astex_1014 8cf459e069ff8dbb2d8388a874ad720b 427 Gene3D G3DSA:3.50.50.60 34 385 1.0E-73 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_1014 8cf459e069ff8dbb2d8388a874ad720b 427 Gene3D G3DSA:3.30.9.10 126 346 1.0E-73 T 13-10-2018 Astex_0288 7ce064d2a034674390f24a07b87337bb 159 SUPERFAMILY SSF55729 10 140 6.0E-27 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Astex_0288 7ce064d2a034674390f24a07b87337bb 159 Pfam PF00583 Acetyltransferase (GNAT) family 46 140 1.6E-15 T 13-10-2018 IPR000182 GNAT domain Astex_0288 7ce064d2a034674390f24a07b87337bb 159 Gene3D G3DSA:3.40.630.30 8 144 1.1E-27 T 13-10-2018 Astex_3457 787551c1fbeb17717cbec007e2db1e30 802 Gene3D G3DSA:1.10.390.60 359 589 1.9E-31 T 13-10-2018 Astex_3457 787551c1fbeb17717cbec007e2db1e30 802 SUPERFAMILY SSF55486 365 591 5.57E-42 T 13-10-2018 Astex_3457 787551c1fbeb17717cbec007e2db1e30 802 Pfam PF01433 Peptidase family M1 domain 381 585 2.4E-16 T 13-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 Astex_2952 1c491d04879ccb67e6bfe578b98e8bc1 300 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 12 64 2.4E-18 T 13-10-2018 IPR025713 Motility protein B, N-terminal domain Astex_2952 1c491d04879ccb67e6bfe578b98e8bc1 300 Gene3D G3DSA:3.30.1330.60 132 299 7.7E-42 T 13-10-2018 IPR036737 OmpA-like domain superfamily Astex_2952 1c491d04879ccb67e6bfe578b98e8bc1 300 SUPERFAMILY SSF103088 178 287 2.62E-18 T 13-10-2018 IPR036737 OmpA-like domain superfamily Astex_2952 1c491d04879ccb67e6bfe578b98e8bc1 300 Pfam PF00691 OmpA family 185 274 1.2E-11 T 13-10-2018 IPR006665 OmpA-like domain Astex_3269 958f3c93f0f1c324cb2bb64299bd57c1 320 Pfam PF01738 Dienelactone hydrolase family 183 291 2.2E-6 T 13-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 Astex_3269 958f3c93f0f1c324cb2bb64299bd57c1 320 SUPERFAMILY SSF53474 85 313 2.99E-26 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_3269 958f3c93f0f1c324cb2bb64299bd57c1 320 Gene3D G3DSA:3.40.50.1820 73 314 8.2E-43 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_3306 3c6b076af935ea9a7ac8a49739630af0 510 SUPERFAMILY SSF51905 14 436 1.89E-31 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_3306 3c6b076af935ea9a7ac8a49739630af0 510 PIRSF PIRSF011396 8 510 2.2E-195 T 13-10-2018 IPR033856 Flavin-dependent tryptophan halogenase Astex_3306 3c6b076af935ea9a7ac8a49739630af0 510 Gene3D G3DSA:3.50.50.60 12 505 2.3E-186 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_3306 3c6b076af935ea9a7ac8a49739630af0 510 Pfam PF04820 Tryptophan halogenase 15 473 4.4E-185 T 13-10-2018 IPR006905 Flavin-dependent halogenase Astex_2627 0cc091d2894b70a3fcc4841e679e987d 594 Gene3D G3DSA:1.10.540.10 20 158 2.5E-17 T 13-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 Astex_2627 0cc091d2894b70a3fcc4841e679e987d 594 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 162 271 7.0E-15 T 13-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 Astex_2627 0cc091d2894b70a3fcc4841e679e987d 594 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 467 589 5.8E-27 T 13-10-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain Astex_2627 0cc091d2894b70a3fcc4841e679e987d 594 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 282 450 1.4E-16 T 13-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Astex_2627 0cc091d2894b70a3fcc4841e679e987d 594 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 3 33 2.8E-12 T 13-10-2018 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria Astex_2627 0cc091d2894b70a3fcc4841e679e987d 594 SUPERFAMILY SSF47203 285 472 5.48E-41 T 13-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 Astex_2627 0cc091d2894b70a3fcc4841e679e987d 594 Gene3D G3DSA:1.20.140.10 286 455 2.0E-39 T 13-10-2018 Astex_2627 0cc091d2894b70a3fcc4841e679e987d 594 Gene3D G3DSA:2.40.110.10 160 285 6.1E-25 T 13-10-2018 Astex_2627 0cc091d2894b70a3fcc4841e679e987d 594 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 38 157 7.4E-12 T 13-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 Astex_2627 0cc091d2894b70a3fcc4841e679e987d 594 SUPERFAMILY SSF56645 37 278 1.44E-55 T 13-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 Astex_2658 eaf82ba6ecbddf626a54ddb5385be6e5 246 Gene3D G3DSA:3.40.50.300 62 244 6.3E-45 T 13-10-2018 Astex_2658 eaf82ba6ecbddf626a54ddb5385be6e5 246 PIRSF PIRSF003073 1 246 1.2E-71 T 13-10-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein Astex_2658 eaf82ba6ecbddf626a54ddb5385be6e5 246 SUPERFAMILY SSF52540 65 240 8.42E-23 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2658 eaf82ba6ecbddf626a54ddb5385be6e5 246 Pfam PF01695 IstB-like ATP binding protein 53 230 6.6E-74 T 13-10-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 Astex_2658 eaf82ba6ecbddf626a54ddb5385be6e5 246 SMART SM00382 98 231 0.0011 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_2658 eaf82ba6ecbddf626a54ddb5385be6e5 246 Pfam PF08483 IstB-like ATP binding N-terminal 25 51 3.6E-9 T 13-10-2018 IPR013690 IstB-like ATP binding N-terminal Astex_0130 839a6ee0bd3e90dad1e6aed808661288 221 PIRSF PIRSF004848 3 221 2.4E-51 T 13-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 Astex_0130 839a6ee0bd3e90dad1e6aed808661288 221 Pfam PF01168 Alanine racemase, N-terminal domain 30 220 3.5E-18 T 13-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 Astex_0130 839a6ee0bd3e90dad1e6aed808661288 221 Hamap MF_02087 Pyridoxal phosphate homeostasis protein. 8 220 22.879 T 13-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 Astex_0130 839a6ee0bd3e90dad1e6aed808661288 221 Gene3D G3DSA:3.20.20.10 6 221 1.5E-64 T 13-10-2018 IPR029066 PLP-binding barrel Astex_0130 839a6ee0bd3e90dad1e6aed808661288 221 SUPERFAMILY SSF51419 7 219 3.4E-61 T 13-10-2018 IPR029066 PLP-binding barrel Astex_0130 839a6ee0bd3e90dad1e6aed808661288 221 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 17 221 4.4E-43 T 13-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 Astex_1003 d4cb6dbd453b741271b35decde58be2a 384 SUPERFAMILY SSF103473 7 374 3.92E-46 T 13-10-2018 IPR036259 MFS transporter superfamily Astex_1003 d4cb6dbd453b741271b35decde58be2a 384 Gene3D G3DSA:1.20.1250.20 194 382 3.1E-12 T 13-10-2018 Astex_1003 d4cb6dbd453b741271b35decde58be2a 384 Gene3D G3DSA:1.20.1250.20 5 193 1.5E-22 T 13-10-2018 Astex_1003 d4cb6dbd453b741271b35decde58be2a 384 Pfam PF07690 Major Facilitator Superfamily 14 329 3.6E-27 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Astex_1694 b69b7c558c2578c544e6709684c5de33 245 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 81 9.8E-19 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Astex_1694 b69b7c558c2578c544e6709684c5de33 245 Gene3D G3DSA:3.40.1410.10 83 244 1.5E-39 T 13-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily Astex_1694 b69b7c558c2578c544e6709684c5de33 245 SUPERFAMILY SSF64288 69 243 5.5E-43 T 13-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily Astex_1694 b69b7c558c2578c544e6709684c5de33 245 Gene3D G3DSA:1.10.10.10 15 82 8.8E-24 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1694 b69b7c558c2578c544e6709684c5de33 245 SMART SM00345 22 81 6.2E-18 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Astex_1694 b69b7c558c2578c544e6709684c5de33 245 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 55 7.3E-10 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Astex_1694 b69b7c558c2578c544e6709684c5de33 245 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 55 71 7.3E-10 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Astex_1694 b69b7c558c2578c544e6709684c5de33 245 SUPERFAMILY SSF46785 12 84 2.66E-21 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_1694 b69b7c558c2578c544e6709684c5de33 245 Pfam PF07702 UTRA domain 101 237 4.2E-34 T 13-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 Astex_1694 b69b7c558c2578c544e6709684c5de33 245 SMART SM00866 101 237 1.8E-32 T 13-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 Astex_3577 0d3bfd276f146436ac8687af1fdbcd74 292 Gene3D G3DSA:1.10.10.10 22 97 2.1E-14 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_3577 0d3bfd276f146436ac8687af1fdbcd74 292 Pfam PF01380 SIS domain 157 282 1.7E-20 T 13-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 Astex_3577 0d3bfd276f146436ac8687af1fdbcd74 292 SUPERFAMILY SSF53697 124 285 1.4E-22 T 13-10-2018 Astex_3577 0d3bfd276f146436ac8687af1fdbcd74 292 SUPERFAMILY SSF46689 26 98 3.4E-14 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Astex_3577 0d3bfd276f146436ac8687af1fdbcd74 292 Gene3D G3DSA:3.40.50.10490 124 291 8.0E-30 T 13-10-2018 Astex_3092 0775d47289355fad07197ac96984deb6 180 SUPERFAMILY SSF52833 5 178 3.95E-52 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Astex_3092 0775d47289355fad07197ac96984deb6 180 Gene3D G3DSA:3.40.30.10 2 180 2.9E-57 T 13-10-2018 Astex_3092 0775d47289355fad07197ac96984deb6 180 ProSitePatterns PS00460 Glutathione peroxidases active site. 24 39 - T 13-10-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 Astex_3092 0775d47289355fad07197ac96984deb6 180 PIRSF PIRSF000303 1 180 4.9E-58 T 13-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 Astex_3092 0775d47289355fad07197ac96984deb6 180 Pfam PF00255 Glutathione peroxidase 5 110 1.1E-34 T 13-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 Astex_3092 0775d47289355fad07197ac96984deb6 180 PRINTS PR01011 Glutathione peroxidase family signature 22 39 3.9E-18 T 13-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 Astex_3092 0775d47289355fad07197ac96984deb6 180 PRINTS PR01011 Glutathione peroxidase family signature 57 73 3.9E-18 T 13-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 Astex_3092 0775d47289355fad07197ac96984deb6 180 PRINTS PR01011 Glutathione peroxidase family signature 140 149 3.9E-18 T 13-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 Astex_1770 36168e1136afde669e72bc989b59eb13 266 Pfam PF00072 Response regulator receiver domain 19 132 2.2E-10 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1770 36168e1136afde669e72bc989b59eb13 266 SUPERFAMILY SSF52172 19 136 1.42E-17 T 13-10-2018 IPR011006 CheY-like superfamily Astex_1770 36168e1136afde669e72bc989b59eb13 266 SMART SM00448 17 132 1.6E-7 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1770 36168e1136afde669e72bc989b59eb13 266 Gene3D G3DSA:3.40.50.2300 7 140 1.3E-16 T 13-10-2018 Astex_1727 388886e4f37fe3a0cac57a819bfdf0ef 267 Pfam PF09916 Uncharacterized protein conserved in bacteria (DUF2145) 50 251 4.8E-56 T 13-10-2018 IPR014547 Uncharacterised conserved protein UCP028477 Astex_3081 8016de4ae376becd5d3dc8cc6a6a4ca8 253 Pfam PF13673 Acetyltransferase (GNAT) domain 142 231 1.0E-11 T 13-10-2018 IPR000182 GNAT domain Astex_3081 8016de4ae376becd5d3dc8cc6a6a4ca8 253 SUPERFAMILY SSF55729 92 251 6.0E-22 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Astex_3081 8016de4ae376becd5d3dc8cc6a6a4ca8 253 Gene3D G3DSA:3.40.630.30 80 251 2.8E-20 T 13-10-2018 Astex_3381 b23e7a6a7d312e8672b25be9c092db9d 329 Pfam PF13621 Cupin-like domain 13 253 1.4E-47 T 13-10-2018 Astex_3381 b23e7a6a7d312e8672b25be9c092db9d 329 Gene3D G3DSA:2.60.120.650 1 257 2.1E-40 T 13-10-2018 Astex_3381 b23e7a6a7d312e8672b25be9c092db9d 329 SMART SM00558 89 260 7.5E-4 T 13-10-2018 IPR003347 JmjC domain Astex_3381 b23e7a6a7d312e8672b25be9c092db9d 329 SUPERFAMILY SSF51197 3 294 3.43E-45 T 13-10-2018 Astex_1517 6bb37b7ab4831b9a439499bf8d3c0744 228 SUPERFAMILY SSF56784 12 225 1.07E-48 T 13-10-2018 IPR036412 HAD-like superfamily Astex_1517 6bb37b7ab4831b9a439499bf8d3c0744 228 Gene3D G3DSA:3.40.50.1000 12 216 6.3E-48 T 13-10-2018 IPR023214 HAD superfamily Astex_1517 6bb37b7ab4831b9a439499bf8d3c0744 228 Gene3D G3DSA:1.10.150.240 24 94 6.3E-48 T 13-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 Astex_1517 6bb37b7ab4831b9a439499bf8d3c0744 228 Hamap MF_00495 Phosphoglycolate phosphatase [gph]. 9 224 31.621 T 13-10-2018 IPR037512 Phosphoglycolate phosphatase, prokaryotic GO:0005975|GO:0008967 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 Astex_1517 6bb37b7ab4831b9a439499bf8d3c0744 228 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 109 189 2.4E-8 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Astex_1517 6bb37b7ab4831b9a439499bf8d3c0744 228 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 12 222 8.0E-52 T 13-10-2018 IPR006346 2-phosphoglycolate phosphatase-like, prokaryotic GO:0016791 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 Astex_1517 6bb37b7ab4831b9a439499bf8d3c0744 228 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 108 121 6.6E-5 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Astex_1517 6bb37b7ab4831b9a439499bf8d3c0744 228 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 139 155 6.6E-5 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Astex_1517 6bb37b7ab4831b9a439499bf8d3c0744 228 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 9 20 6.6E-5 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Astex_1517 6bb37b7ab4831b9a439499bf8d3c0744 228 Pfam PF13419 Haloacid dehalogenase-like hydrolase 12 195 1.1E-28 T 13-10-2018 Astex_0900 b96497cbd432f212d2543ffaa9452e82 372 Pfam PF01757 Acyltransferase family 21 342 1.2E-17 T 13-10-2018 IPR002656 Acyltransferase 3 GO:0016747 Astex_3211 7afcc7f1472f53a2ef362dd69e1470eb 678 Gene3D G3DSA:2.60.40.10 56 177 1.6E-21 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_3211 7afcc7f1472f53a2ef362dd69e1470eb 678 SUPERFAMILY SSF81296 62 177 2.24E-14 T 13-10-2018 IPR014756 Immunoglobulin E-set Astex_3211 7afcc7f1472f53a2ef362dd69e1470eb 678 Pfam PF02927 Cellulase N-terminal ig-like domain 65 163 1.7E-13 T 13-10-2018 IPR004197 Cellulase, Ig-like domain GO:0005975|GO:0008810 Astex_3211 7afcc7f1472f53a2ef362dd69e1470eb 678 SUPERFAMILY SSF48208 176 677 1.13E-73 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 Astex_3211 7afcc7f1472f53a2ef362dd69e1470eb 678 Pfam PF00759 Glycosyl hydrolase family 9 181 671 5.1E-58 T 13-10-2018 IPR001701 Glycoside hydrolase family 9 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 Astex_3211 7afcc7f1472f53a2ef362dd69e1470eb 678 Gene3D G3DSA:1.50.10.10 179 678 8.6E-100 T 13-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 Astex_0924 7cf98db003000a2df062065244f41ea6 386 PIRSF PIRSF000267 5 384 8.6E-107 T 13-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 Astex_0924 7cf98db003000a2df062065244f41ea6 386 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 10 369 8.7E-95 T 13-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 Astex_0924 7cf98db003000a2df062065244f41ea6 386 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 5 382 5.6E-126 T 13-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 Astex_1439 27f209e439ffb1343eb4dddcae39fdcd 199 Pfam PF13505 Outer membrane protein beta-barrel domain 9 199 4.5E-20 T 13-10-2018 IPR027385 Outer membrane protein beta-barrel Astex_1439 27f209e439ffb1343eb4dddcae39fdcd 199 SUPERFAMILY SSF56925 22 199 7.85E-24 T 13-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel Astex_1439 27f209e439ffb1343eb4dddcae39fdcd 199 Gene3D G3DSA:2.40.160.20 22 199 8.8E-14 T 13-10-2018 Astex_0710 9151ae26c6cca500e2469ec0be41ab70 308 Gene3D G3DSA:3.20.10.10 138 288 4.6E-95 T 13-10-2018 Astex_0710 9151ae26c6cca500e2469ec0be41ab70 308 Pfam PF01063 Amino-transferase class IV 35 268 1.3E-46 T 13-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 Astex_0710 9151ae26c6cca500e2469ec0be41ab70 308 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 9 307 2.1E-125 T 13-10-2018 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767 Astex_0710 9151ae26c6cca500e2469ec0be41ab70 308 Gene3D G3DSA:3.30.470.10 9 127 4.6E-95 T 13-10-2018 Astex_0710 9151ae26c6cca500e2469ec0be41ab70 308 ProSitePatterns PS00770 Aminotransferases class-IV signature. 194 223 - T 13-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 Astex_0710 9151ae26c6cca500e2469ec0be41ab70 308 SUPERFAMILY SSF56752 5 304 6.15E-96 T 13-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 Astex_0324 d12980759bd9e746881c008f4c25974a 521 TIGRFAM TIGR01613 primase_Cterm: phage/plasmid primase, P4 family, C-terminal domain 147 457 2.2E-67 T 13-10-2018 IPR006500 DNA primase, phage/plasmid Astex_0324 d12980759bd9e746881c008f4c25974a 521 SMART SM00885 37 201 3.8E-13 T 13-10-2018 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal Astex_0324 d12980759bd9e746881c008f4c25974a 521 SUPERFAMILY SSF52540 225 385 3.08E-7 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0324 d12980759bd9e746881c008f4c25974a 521 Pfam PF08706 D5 N terminal like 59 198 1.4E-17 T 13-10-2018 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal Astex_0551 8f89af01ce80001754ed34433efdbd70 648 Pfam PF07969 Amidohydrolase family 79 563 3.3E-113 T 13-10-2018 IPR013108 Amidohydrolase 3 Astex_0551 8f89af01ce80001754ed34433efdbd70 648 Gene3D G3DSA:3.20.20.140 91 522 4.5E-89 T 13-10-2018 Astex_0551 8f89af01ce80001754ed34433efdbd70 648 SUPERFAMILY SSF51338 26 569 1.03E-20 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Astex_0551 8f89af01ce80001754ed34433efdbd70 648 Gene3D G3DSA:2.30.40.10 38 538 4.5E-89 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 Astex_0551 8f89af01ce80001754ed34433efdbd70 648 SUPERFAMILY SSF51556 90 522 2.24E-43 T 13-10-2018 IPR032466 Metal-dependent hydrolase Astex_0551 8f89af01ce80001754ed34433efdbd70 648 Gene3D G3DSA:3.10.310.70 110 221 4.5E-89 T 13-10-2018 Astex_2661 254dbb47cf709c6b7cfe1695f75ed3e5 92 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 11 61 8.4E-18 T 13-10-2018 IPR010260 DNA-binding transcriptional activator AlpA Astex_2661 254dbb47cf709c6b7cfe1695f75ed3e5 92 SUPERFAMILY SSF46955 14 68 2.38E-5 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily Astex_1444 1444224b353b85d9cd704ed5f291db85 311 Pfam PF13533 Biotin-lipoyl like 33 79 4.6E-11 T 13-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain Astex_1444 1444224b353b85d9cd704ed5f291db85 311 SUPERFAMILY SSF111369 161 245 4.32E-6 T 13-10-2018 Astex_1444 1444224b353b85d9cd704ed5f291db85 311 Gene3D G3DSA:2.40.50.100 32 229 1.9E-31 T 13-10-2018 Astex_1444 1444224b353b85d9cd704ed5f291db85 311 Gene3D G3DSA:2.40.30.170 25 274 1.9E-31 T 13-10-2018 Astex_1444 1444224b353b85d9cd704ed5f291db85 311 SUPERFAMILY SSF111369 25 88 1.01E-6 T 13-10-2018 Astex_1444 1444224b353b85d9cd704ed5f291db85 311 Pfam PF13437 HlyD family secretion protein 196 280 7.6E-12 T 13-10-2018 Astex_1444 1444224b353b85d9cd704ed5f291db85 311 Gene3D G3DSA:1.10.287.470 66 195 1.9E-31 T 13-10-2018 Astex_1444 1444224b353b85d9cd704ed5f291db85 311 SUPERFAMILY SSF111369 101 155 5.23E-6 T 13-10-2018 Astex_1068 e5f7198ba31211ca1322093944b587f5 117 Pfam PF01627 Hpt domain 52 99 1.5E-6 T 13-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 Astex_1068 e5f7198ba31211ca1322093944b587f5 117 SUPERFAMILY SSF47226 10 104 2.22E-15 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 Astex_1068 e5f7198ba31211ca1322093944b587f5 117 Gene3D G3DSA:1.20.120.160 2 117 2.1E-22 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 Astex_0140 39767661e69e1bff6e8e59daf1b2a243 620 Gene3D G3DSA:3.50.50.60 292 455 8.6E-57 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_0140 39767661e69e1bff6e8e59daf1b2a243 620 Gene3D G3DSA:3.50.50.60 1 223 6.1E-92 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_0140 39767661e69e1bff6e8e59daf1b2a243 620 SMART SM01228 539 610 3.5E-39 T 13-10-2018 Astex_0140 39767661e69e1bff6e8e59daf1b2a243 620 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 3 617 40.415 T 13-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 Astex_0140 39767661e69e1bff6e8e59daf1b2a243 620 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 270 284 - T 13-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 Astex_0140 39767661e69e1bff6e8e59daf1b2a243 620 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 365 388 - T 13-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 Astex_0140 39767661e69e1bff6e8e59daf1b2a243 620 Pfam PF01134 Glucose inhibited division protein A 6 394 2.6E-159 T 13-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 Astex_0140 39767661e69e1bff6e8e59daf1b2a243 620 SUPERFAMILY SSF51905 5 255 2.22E-45 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_0140 39767661e69e1bff6e8e59daf1b2a243 620 Pfam PF13932 GidA associated domain 398 609 5.4E-72 T 13-10-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 Astex_0140 39767661e69e1bff6e8e59daf1b2a243 620 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 6 614 1.7E-244 T 13-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 Astex_0140 39767661e69e1bff6e8e59daf1b2a243 620 Gene3D G3DSA:1.10.150.570 562 615 1.8E-21 T 13-10-2018 Astex_1060 195c0e06cfdc45122d2fd63c7d965ad8 351 SUPERFAMILY SSF56219 30 346 2.88E-21 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily Astex_1060 195c0e06cfdc45122d2fd63c7d965ad8 351 Gene3D G3DSA:3.60.10.10 30 348 3.3E-26 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily Astex_1060 195c0e06cfdc45122d2fd63c7d965ad8 351 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 34 339 2.5E-6 T 13-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase Astex_2972 51881f968dbb82fb9a34d07ff8982cc2 297 SUPERFAMILY SSF51569 9 296 9.11E-107 T 13-10-2018 Astex_2972 51881f968dbb82fb9a34d07ff8982cc2 297 Pfam PF00701 Dihydrodipicolinate synthetase family 10 294 2.2E-98 T 13-10-2018 IPR002220 DapA-like GO:0016829 Astex_2972 51881f968dbb82fb9a34d07ff8982cc2 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 78 96 3.2E-35 T 13-10-2018 IPR002220 DapA-like GO:0016829 Astex_2972 51881f968dbb82fb9a34d07ff8982cc2 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 42 63 3.2E-35 T 13-10-2018 IPR002220 DapA-like GO:0016829 Astex_2972 51881f968dbb82fb9a34d07ff8982cc2 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 135 152 3.2E-35 T 13-10-2018 IPR002220 DapA-like GO:0016829 Astex_2972 51881f968dbb82fb9a34d07ff8982cc2 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 110 126 3.2E-35 T 13-10-2018 IPR002220 DapA-like GO:0016829 Astex_2972 51881f968dbb82fb9a34d07ff8982cc2 297 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 9 294 65.921 T 13-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Astex_2972 51881f968dbb82fb9a34d07ff8982cc2 297 Gene3D G3DSA:3.20.20.70 9 295 4.5E-115 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_2972 51881f968dbb82fb9a34d07ff8982cc2 297 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 12 293 7.8E-102 T 13-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 Astex_2972 51881f968dbb82fb9a34d07ff8982cc2 297 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 140 170 - T 13-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 Astex_2972 51881f968dbb82fb9a34d07ff8982cc2 297 PIRSF PIRSF001365 7 297 7.5E-102 T 13-10-2018 IPR002220 DapA-like GO:0016829 Astex_2972 51881f968dbb82fb9a34d07ff8982cc2 297 SMART SM01130 9 296 1.3E-147 T 13-10-2018 IPR002220 DapA-like GO:0016829 Astex_0604 dcf9389cdc2c285afdbf846f9708cae4 462 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 370 379 - T 13-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Astex_0604 dcf9389cdc2c285afdbf846f9708cae4 462 Gene3D G3DSA:3.40.50.12240 28 462 7.3E-135 T 13-10-2018 Astex_0604 dcf9389cdc2c285afdbf846f9708cae4 462 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 22 459 6.8E-153 T 13-10-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Astex_0604 dcf9389cdc2c285afdbf846f9708cae4 462 TIGRFAM TIGR03498 FliI_clade3: flagellar protein export ATPase FliI 37 459 2.9E-191 T 13-10-2018 IPR022426 Flagellum-specific ATP synthase FliI, clade 3 GO:0009288|GO:0016887|GO:0030257|GO:0044781 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Astex_0604 dcf9389cdc2c285afdbf846f9708cae4 462 SUPERFAMILY SSF52540 109 383 1.03E-84 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0604 dcf9389cdc2c285afdbf846f9708cae4 462 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 163 379 1.1E-67 T 13-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 Astex_0604 dcf9389cdc2c285afdbf846f9708cae4 462 SMART SM00382 175 364 6.9E-6 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_2054 a155256664488de51408d8c5f79be9bd 308 PIRSF PIRSF037112 1 307 3.9E-93 T 13-10-2018 IPR017113 Antirestriction, ArdC Astex_2054 a155256664488de51408d8c5f79be9bd 308 Pfam PF08401 Domain of unknown function (DUF1738) 10 119 6.1E-31 T 13-10-2018 IPR013610 Domain of unknown function DUF1738 Astex_0439 693df371ef004116386a6ca4211792d1 284 Gene3D G3DSA:3.30.70.260 189 277 7.1E-16 T 13-10-2018 Astex_0439 693df371ef004116386a6ca4211792d1 284 Gene3D G3DSA:3.40.190.10 89 170 3.6E-24 T 13-10-2018 Astex_0439 693df371ef004116386a6ca4211792d1 284 SUPERFAMILY SSF55021 188 274 7.33E-17 T 13-10-2018 Astex_0439 693df371ef004116386a6ca4211792d1 284 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 157 179 - T 13-10-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 Astex_0439 693df371ef004116386a6ca4211792d1 284 PIRSF PIRSF001500 1 278 1.8E-57 T 13-10-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 Astex_0439 693df371ef004116386a6ca4211792d1 284 SUPERFAMILY SSF53850 6 185 4.07E-58 T 13-10-2018 Astex_0439 693df371ef004116386a6ca4211792d1 284 Gene3D G3DSA:3.40.190.10 1 88 9.9E-28 T 13-10-2018 Astex_0439 693df371ef004116386a6ca4211792d1 284 Pfam PF00800 Prephenate dehydratase 7 182 4.5E-52 T 13-10-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 Astex_3068 081f1da96759ed4957338ffb0bccbdf2 83 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 9 82 1.0E-22 T 13-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 Astex_3068 081f1da96759ed4957338ffb0bccbdf2 83 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 1 82 1.2E-24 T 13-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 Astex_3068 081f1da96759ed4957338ffb0bccbdf2 83 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 1 82 20.548 T 13-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 Astex_3068 081f1da96759ed4957338ffb0bccbdf2 83 Gene3D G3DSA:3.30.1280.10 1 83 2.7E-27 T 13-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Astex_3068 081f1da96759ed4957338ffb0bccbdf2 83 SUPERFAMILY SSF82697 1 82 1.01E-23 T 13-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Astex_3068 081f1da96759ed4957338ffb0bccbdf2 83 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 2 82 2.2E-30 T 13-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 Astex_0383 5b2788c5abc97304b153c3f8fb725a69 278 PIRSF PIRSF031679 8 278 2.3E-72 T 13-10-2018 IPR016980 S-adenosyl-L-methionine dependent methyltransferase, Alr7345, predicted Astex_0383 5b2788c5abc97304b153c3f8fb725a69 278 SUPERFAMILY SSF53335 68 230 1.39E-13 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Astex_0383 5b2788c5abc97304b153c3f8fb725a69 278 Gene3D G3DSA:3.40.50.150 50 228 1.6E-13 T 13-10-2018 Astex_0383 5b2788c5abc97304b153c3f8fb725a69 278 Pfam PF08241 Methyltransferase domain 91 184 2.2E-4 T 13-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 Astex_0043 030ac1bc91696a39a16e0b30417be517 318 SUPERFAMILY SSF56059 125 312 2.55E-52 T 13-10-2018 Astex_0043 030ac1bc91696a39a16e0b30417be517 318 SUPERFAMILY SSF52440 3 123 2.88E-42 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily Astex_0043 030ac1bc91696a39a16e0b30417be517 318 Pfam PF02955 Prokaryotic glutathione synthetase, ATP-grasp domain 125 295 3.0E-67 T 13-10-2018 IPR004218 Prokaryotic glutathione synthetase, ATP-binding GO:0004363|GO:0005524|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 Astex_0043 030ac1bc91696a39a16e0b30417be517 318 Gene3D G3DSA:3.30.1490.20 138 202 7.2E-109 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 Astex_0043 030ac1bc91696a39a16e0b30417be517 318 Pfam PF02951 Prokaryotic glutathione synthetase, N-terminal domain 3 121 1.3E-43 T 13-10-2018 IPR004215 Prokaryotic glutathione synthetase, N-terminal GO:0004363|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 Astex_0043 030ac1bc91696a39a16e0b30417be517 318 Gene3D G3DSA:3.40.50.20 9 115 7.2E-109 T 13-10-2018 Astex_0043 030ac1bc91696a39a16e0b30417be517 318 Hamap MF_00162 Glutathione synthetase [gshB]. 1 316 146.591 T 13-10-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 Astex_0043 030ac1bc91696a39a16e0b30417be517 318 TIGRFAM TIGR01380 glut_syn: glutathione synthase 3 312 1.4E-125 T 13-10-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 Astex_0043 030ac1bc91696a39a16e0b30417be517 318 Gene3D G3DSA:3.30.470.20 116 295 7.2E-109 T 13-10-2018 Astex_1928 752c75d58a859c459ec83d3aadf264f6 303 Gene3D G3DSA:2.120.10.30 6 298 7.8E-101 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like Astex_1928 752c75d58a859c459ec83d3aadf264f6 303 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 39 290 4.8E-62 T 13-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region Astex_1928 752c75d58a859c459ec83d3aadf264f6 303 SUPERFAMILY SSF63829 2 302 7.63E-67 T 13-10-2018 Astex_1928 752c75d58a859c459ec83d3aadf264f6 303 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 228 245 1.0E-11 T 13-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) Astex_1928 752c75d58a859c459ec83d3aadf264f6 303 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 272 290 1.0E-11 T 13-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) Astex_1928 752c75d58a859c459ec83d3aadf264f6 303 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 168 190 1.0E-11 T 13-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) Astex_1928 752c75d58a859c459ec83d3aadf264f6 303 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 40 57 1.0E-11 T 13-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) Astex_2165 1ba1c33ab5d03e5acb426c27c9444c29 543 Gene3D G3DSA:1.25.40.10 41 230 8.5E-13 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_2165 1ba1c33ab5d03e5acb426c27c9444c29 543 Pfam PF00263 Bacterial type II and III secretion system protein 320 468 9.5E-23 T 13-10-2018 IPR004846 Type II/III secretion system GO:0009306 Astex_2165 1ba1c33ab5d03e5acb426c27c9444c29 543 SUPERFAMILY SSF48452 42 208 3.79E-10 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_3610 4b0a2aa8265d2d6379927f729c935246 547 PIRSF PIRSF001092 35 535 2.4E-62 T 13-10-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 Astex_3610 4b0a2aa8265d2d6379927f729c935246 547 Pfam PF01120 Alpha-L-fucosidase 37 432 1.8E-91 T 13-10-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 Astex_3610 4b0a2aa8265d2d6379927f729c935246 547 SMART SM00812 40 496 2.8E-153 T 13-10-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 Astex_3610 4b0a2aa8265d2d6379927f729c935246 547 SUPERFAMILY SSF51445 40 437 1.9E-78 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_3610 4b0a2aa8265d2d6379927f729c935246 547 Gene3D G3DSA:2.60.40.1180 438 545 2.0E-28 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta Astex_3610 4b0a2aa8265d2d6379927f729c935246 547 Pfam PF16757 Alpha-L-fucosidase C-terminal domain 462 536 1.1E-6 T 13-10-2018 IPR031919 Alpha-L-fucosidase, C-terminal KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 Astex_3610 4b0a2aa8265d2d6379927f729c935246 547 Gene3D G3DSA:3.20.20.80 36 237 2.2E-56 T 13-10-2018 Astex_3610 4b0a2aa8265d2d6379927f729c935246 547 Gene3D G3DSA:3.20.20.80 242 437 1.7E-40 T 13-10-2018 Astex_3592 2b0e02bef2565f54891560fca9b0ecf5 282 Gene3D G3DSA:2.60.120.10 12 267 4.2E-102 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Astex_3592 2b0e02bef2565f54891560fca9b0ecf5 282 Pfam PF04962 KduI/IolB family 72 267 5.3E-29 T 13-10-2018 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 Astex_3592 2b0e02bef2565f54891560fca9b0ecf5 282 Gene3D G3DSA:2.60.120.520 32 148 4.2E-102 T 13-10-2018 IPR027449 5-keto-4-deoxyuronate isomerase, N-terminal KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 Astex_3592 2b0e02bef2565f54891560fca9b0ecf5 282 PIRSF PIRSF006625 3 282 3.6E-114 T 13-10-2018 IPR007045 5-keto 4-deoxyuronate isomerase GO:0008697|GO:0045490 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 Astex_3592 2b0e02bef2565f54891560fca9b0ecf5 282 SUPERFAMILY SSF51182 4 266 4.46E-90 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily Astex_3592 2b0e02bef2565f54891560fca9b0ecf5 282 Hamap MF_00687 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase [kduI]. 3 282 48.432 T 13-10-2018 IPR007045 5-keto 4-deoxyuronate isomerase GO:0008697|GO:0045490 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 Astex_0120 faa0b3c0b6cb366f44f7688e069453a6 176 Pfam PF03968 OstA-like protein 37 141 2.7E-21 T 13-10-2018 IPR005653 Organic solvent tolerance-like, N-terminal Astex_0120 faa0b3c0b6cb366f44f7688e069453a6 176 TIGRFAM TIGR03002 outer_YhbN_LptA: lipopolysaccharide transport periplasmic protein LptA 29 166 9.0E-24 T 13-10-2018 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 Astex_0120 faa0b3c0b6cb366f44f7688e069453a6 176 Gene3D G3DSA:2.60.450.10 28 163 4.0E-22 T 13-10-2018 Astex_0378 7bbccab3a2e5267039eb906c7a620c91 305 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 19 280 3.1E-16 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Astex_0378 7bbccab3a2e5267039eb906c7a620c91 305 SUPERFAMILY SSF51905 6 299 9.61E-30 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_0378 7bbccab3a2e5267039eb906c7a620c91 305 Gene3D G3DSA:3.50.50.60 145 208 1.8E-6 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_0378 7bbccab3a2e5267039eb906c7a620c91 305 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 161 179 1.3E-17 T 13-10-2018 Astex_0378 7bbccab3a2e5267039eb906c7a620c91 305 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 122 140 1.3E-17 T 13-10-2018 Astex_0378 7bbccab3a2e5267039eb906c7a620c91 305 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 19 38 1.3E-17 T 13-10-2018 Astex_0378 7bbccab3a2e5267039eb906c7a620c91 305 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 256 278 1.3E-17 T 13-10-2018 Astex_0378 7bbccab3a2e5267039eb906c7a620c91 305 Gene3D G3DSA:3.50.50.60 13 144 4.7E-19 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_0378 7bbccab3a2e5267039eb906c7a620c91 305 Gene3D G3DSA:3.50.50.60 211 305 2.6E-8 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_0378 7bbccab3a2e5267039eb906c7a620c91 305 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 157 181 8.6E-14 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Astex_0378 7bbccab3a2e5267039eb906c7a620c91 305 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 73 83 8.6E-14 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Astex_0378 7bbccab3a2e5267039eb906c7a620c91 305 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 18 40 8.6E-14 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Astex_0378 7bbccab3a2e5267039eb906c7a620c91 305 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 123 131 8.6E-14 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Astex_1466 ceb9e8d848a3ad2732225dcf1be0c351 451 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 15 449 2.8E-93 T 13-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 Astex_1466 ceb9e8d848a3ad2732225dcf1be0c351 451 Pfam PF02321 Outer membrane efflux protein 272 440 1.1E-19 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Astex_1466 ceb9e8d848a3ad2732225dcf1be0c351 451 Pfam PF02321 Outer membrane efflux protein 60 241 1.7E-15 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Astex_1466 ceb9e8d848a3ad2732225dcf1be0c351 451 Gene3D G3DSA:1.20.1600.10 50 449 1.7E-94 T 13-10-2018 Astex_1466 ceb9e8d848a3ad2732225dcf1be0c351 451 SUPERFAMILY SSF56954 3 449 2.49E-82 T 13-10-2018 Astex_1466 ceb9e8d848a3ad2732225dcf1be0c351 451 Gene3D G3DSA:2.20.200.10 95 335 1.7E-94 T 13-10-2018 Astex_0542 00f1ddd69c7c30de41717f37fe4ed639 751 Gene3D G3DSA:2.170.130.10 60 174 6.9E-22 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_0542 00f1ddd69c7c30de41717f37fe4ed639 751 Gene3D G3DSA:2.40.170.20 175 718 1.9E-42 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_0542 00f1ddd69c7c30de41717f37fe4ed639 751 SUPERFAMILY SSF56935 40 751 1.31E-80 T 13-10-2018 Astex_0542 00f1ddd69c7c30de41717f37fe4ed639 751 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 734 751 - T 13-10-2018 IPR010917 TonB-dependent receptor, conserved site Astex_0542 00f1ddd69c7c30de41717f37fe4ed639 751 Pfam PF07715 TonB-dependent Receptor Plug Domain 60 167 2.1E-17 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_2901 a9d80691f7d0b385dd31fb38ccf54df1 569 Gene3D G3DSA:1.20.1530.20 6 400 5.8E-76 T 13-10-2018 IPR038770 Sodium/solute symporter superfamily Astex_2901 a9d80691f7d0b385dd31fb38ccf54df1 569 Pfam PF02254 TrkA-N domain 433 544 3.7E-23 T 13-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 Astex_2901 a9d80691f7d0b385dd31fb38ccf54df1 569 Pfam PF00999 Sodium/hydrogen exchanger family 16 390 1.2E-73 T 13-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 Astex_2901 a9d80691f7d0b385dd31fb38ccf54df1 569 SUPERFAMILY SSF51735 432 561 9.47E-29 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_2901 a9d80691f7d0b385dd31fb38ccf54df1 569 Gene3D G3DSA:3.40.50.720 427 566 6.7E-31 T 13-10-2018 Astex_1477 eae4d9128a5c463add781660a4fe69eb 391 Pfam PF06114 IrrE N-terminal-like domain 279 341 1.2E-7 T 13-10-2018 IPR010359 IrrE N-terminal-like domain Astex_1477 eae4d9128a5c463add781660a4fe69eb 391 SUPERFAMILY SSF47413 51 112 2.49E-11 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Astex_1477 eae4d9128a5c463add781660a4fe69eb 391 Gene3D G3DSA:1.10.260.40 52 116 6.5E-11 T 13-10-2018 Astex_1477 eae4d9128a5c463add781660a4fe69eb 391 SMART SM00530 54 110 2.1E-8 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Astex_1477 eae4d9128a5c463add781660a4fe69eb 391 Pfam PF01381 Helix-turn-helix 58 107 2.7E-9 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Astex_2973 1739fddc4c387c9654f6be1dddc8564e 734 SUPERFAMILY SSF53955 549 691 9.01E-37 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily Astex_2973 1739fddc4c387c9654f6be1dddc8564e 734 Gene3D G3DSA:1.25.40.10 255 427 9.0E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_2973 1739fddc4c387c9654f6be1dddc8564e 734 SUPERFAMILY SSF48435 71 527 2.35E-36 T 13-10-2018 IPR008939 Lytic transglycosylase, superhelical U-shaped GO:0004553|GO:0042597 Astex_2973 1739fddc4c387c9654f6be1dddc8564e 734 Pfam PF01464 Transglycosylase SLT domain 549 641 3.4E-22 T 13-10-2018 IPR008258 Transglycosylase SLT domain 1 Astex_2973 1739fddc4c387c9654f6be1dddc8564e 734 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 554 582 - T 13-10-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 Astex_2973 1739fddc4c387c9654f6be1dddc8564e 734 Gene3D G3DSA:1.10.530.10 546 690 3.7E-37 T 13-10-2018 Astex_2262 c7d3db643dc7f97ff10b6046295e4724 703 Gene3D G3DSA:1.10.1370.40 60 696 2.8E-213 T 13-10-2018 Astex_2262 c7d3db643dc7f97ff10b6046295e4724 703 SUPERFAMILY SSF55486 39 701 5.62E-175 T 13-10-2018 Astex_2262 c7d3db643dc7f97ff10b6046295e4724 703 Pfam PF01432 Peptidase family M3 256 700 1.1E-116 T 13-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 Astex_2262 c7d3db643dc7f97ff10b6046295e4724 703 Gene3D G3DSA:1.10.1370.10 171 632 2.8E-213 T 13-10-2018 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 Astex_3513 7777dbbdb748d698251ce346bcad51f4 347 TIGRFAM TIGR00682 lpxK: tetraacyldisaccharide 4'-kinase 29 325 9.4E-49 T 13-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 Astex_3513 7777dbbdb748d698251ce346bcad51f4 347 SUPERFAMILY SSF52540 55 160 2.66E-6 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_3513 7777dbbdb748d698251ce346bcad51f4 347 Hamap MF_00409 Tetraacyldisaccharide 4'-kinase [lpxK]. 9 343 29.521 T 13-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 Astex_3513 7777dbbdb748d698251ce346bcad51f4 347 Pfam PF02606 Tetraacyldisaccharide-1-P 4'-kinase 27 329 2.3E-71 T 13-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 Astex_0360 f80cad8cf069552b35b388375ed360f1 294 Gene3D G3DSA:3.40.50.1820 30 274 5.5E-57 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_0360 f80cad8cf069552b35b388375ed360f1 294 SUPERFAMILY SSF53474 34 267 7.42E-45 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_0360 f80cad8cf069552b35b388375ed360f1 294 Pfam PF07859 alpha/beta hydrolase fold 76 165 6.0E-15 T 13-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 Astex_2659 05c46f3ecd610d0ef022af8380091c2e 520 Pfam PF00665 Integrase core domain 141 270 1.8E-15 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 Astex_2659 05c46f3ecd610d0ef022af8380091c2e 520 SUPERFAMILY SSF53098 181 309 5.56E-5 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily Astex_2626 4a58adc16d13bd7162a5e42eedadd75f 160 Gene3D G3DSA:3.40.30.10 1 160 2.7E-60 T 13-10-2018 Astex_2626 4a58adc16d13bd7162a5e42eedadd75f 160 SUPERFAMILY SSF52833 1 159 1.88E-38 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Astex_2626 4a58adc16d13bd7162a5e42eedadd75f 160 Pfam PF08534 Redoxin 4 157 1.6E-34 T 13-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 Astex_3826 945fd594f5aa0c08ab490b106959036d 138 SMART SM00422 6 75 1.9E-28 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Astex_3826 945fd594f5aa0c08ab490b106959036d 138 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 42 62 1.6E-12 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Astex_3826 945fd594f5aa0c08ab490b106959036d 138 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 18 31 1.6E-12 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Astex_3826 945fd594f5aa0c08ab490b106959036d 138 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 7 18 1.6E-12 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Astex_3826 945fd594f5aa0c08ab490b106959036d 138 SUPERFAMILY SSF46955 6 131 2.86E-38 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily Astex_3826 945fd594f5aa0c08ab490b106959036d 138 Pfam PF09278 MerR, DNA binding 49 112 1.2E-21 T 13-10-2018 IPR015358 Transcription regulator MerR, DNA binding Astex_3826 945fd594f5aa0c08ab490b106959036d 138 Gene3D G3DSA:1.10.1660.10 1 130 3.6E-38 T 13-10-2018 Astex_3826 945fd594f5aa0c08ab490b106959036d 138 Pfam PF00376 MerR family regulatory protein 7 44 4.8E-15 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Astex_2258 1b0f0035ef95c78dea8121723b37f207 290 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 285 5.3E-149 T 13-10-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 Astex_2258 1b0f0035ef95c78dea8121723b37f207 290 Pfam PF00483 Nucleotidyl transferase 2 237 4.3E-67 T 13-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Astex_2258 1b0f0035ef95c78dea8121723b37f207 290 Gene3D G3DSA:3.90.550.10 1 289 4.2E-80 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_2258 1b0f0035ef95c78dea8121723b37f207 290 SUPERFAMILY SSF53448 1 286 5.86E-86 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_2841 73a0d43e8a612535a9f3b016bd29f123 237 SMART SM00382 40 228 6.4E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_2841 73a0d43e8a612535a9f3b016bd29f123 237 Gene3D G3DSA:3.40.50.300 8 236 6.9E-63 T 13-10-2018 Astex_2841 73a0d43e8a612535a9f3b016bd29f123 237 Pfam PF00005 ABC transporter 31 179 2.4E-31 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_2841 73a0d43e8a612535a9f3b016bd29f123 237 SUPERFAMILY SSF52540 11 232 2.73E-64 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2841 73a0d43e8a612535a9f3b016bd29f123 237 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Astex_0937 8d807506754d254ed13af54b3c7f4451 453 SMART SM00283 192 439 7.9E-36 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_0937 8d807506754d254ed13af54b3c7f4451 453 Gene3D G3DSA:1.10.287.950 157 451 2.4E-52 T 13-10-2018 Astex_0937 8d807506754d254ed13af54b3c7f4451 453 Gene3D G3DSA:1.10.490.10 6 156 2.1E-44 T 13-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 Astex_0937 8d807506754d254ed13af54b3c7f4451 453 SUPERFAMILY SSF46458 6 151 4.12E-34 T 13-10-2018 IPR009050 Globin-like superfamily Astex_0937 8d807506754d254ed13af54b3c7f4451 453 Pfam PF11563 Protoglobin 5 156 2.1E-39 T 13-10-2018 Astex_0937 8d807506754d254ed13af54b3c7f4451 453 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 251 411 5.5E-30 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_0937 8d807506754d254ed13af54b3c7f4451 453 SUPERFAMILY SSF58104 191 438 2.75E-58 T 13-10-2018 Astex_0937 8d807506754d254ed13af54b3c7f4451 453 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 206 235 1.7E-19 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_0937 8d807506754d254ed13af54b3c7f4451 453 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 312 341 1.7E-19 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_0937 8d807506754d254ed13af54b3c7f4451 453 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 360 389 1.7E-19 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_0937 8d807506754d254ed13af54b3c7f4451 453 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 283 310 1.7E-19 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_0519 54e25beb3646de85d8b0db9bee094e21 305 Pfam PF01963 TraB family 38 297 2.6E-65 T 13-10-2018 IPR002816 Pheromone shutdown, TraB Astex_1690 9be476cccd4e3712c1f6cc56c145ac26 725 Gene3D G3DSA:2.40.160.50 400 725 4.4E-69 T 13-10-2018 Astex_1690 9be476cccd4e3712c1f6cc56c145ac26 725 Gene3D G3DSA:3.10.20.310 320 398 2.0E-12 T 13-10-2018 Astex_1690 9be476cccd4e3712c1f6cc56c145ac26 725 Pfam PF01103 Surface antigen 437 725 1.8E-43 T 13-10-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 Astex_0228 c15f5d218b1fd80d5bef3afffc68b614 145 Gene3D G3DSA:3.10.180.10 7 142 2.4E-40 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Astex_0228 c15f5d218b1fd80d5bef3afffc68b614 145 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 5 130 7.6E-5 T 13-10-2018 IPR028973 PhnB-like Astex_0228 c15f5d218b1fd80d5bef3afffc68b614 145 SUPERFAMILY SSF54593 3 134 1.65E-30 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Astex_2759 47946acb3dc2a680e1b5bc8d05f6b916 172 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 99 2.6E-33 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type Astex_2759 47946acb3dc2a680e1b5bc8d05f6b916 172 Pfam PF02082 Transcriptional regulator 1 83 7.5E-28 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type Astex_2759 47946acb3dc2a680e1b5bc8d05f6b916 172 SUPERFAMILY SSF46785 2 152 2.88E-31 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_2759 47946acb3dc2a680e1b5bc8d05f6b916 172 Gene3D G3DSA:1.10.10.10 1 161 3.4E-46 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_2759 47946acb3dc2a680e1b5bc8d05f6b916 172 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 13-10-2018 IPR030489 Transcription regulator Rrf2-type, conserved site Astex_2064 7132b22680f85f0b62840c07d9932cff 400 Gene3D G3DSA:1.20.1250.20 16 398 1.6E-45 T 13-10-2018 Astex_2064 7132b22680f85f0b62840c07d9932cff 400 SUPERFAMILY SSF103473 6 393 1.7E-54 T 13-10-2018 IPR036259 MFS transporter superfamily Astex_2064 7132b22680f85f0b62840c07d9932cff 400 Pfam PF07690 Major Facilitator Superfamily 29 339 7.8E-32 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Astex_0684 72f819d1c17797893b5990eaddef863d 105 Gene3D G3DSA:1.10.10.10 1 102 6.1E-30 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_0684 72f819d1c17797893b5990eaddef863d 105 SUPERFAMILY SSF46785 3 92 2.84E-25 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_0684 72f819d1c17797893b5990eaddef863d 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 4 19 3.1E-9 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Astex_0684 72f819d1c17797893b5990eaddef863d 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 36 51 3.1E-9 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Astex_0684 72f819d1c17797893b5990eaddef863d 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 51 66 3.1E-9 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Astex_0684 72f819d1c17797893b5990eaddef863d 105 SMART SM00418 2 80 1.9E-21 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Astex_0684 72f819d1c17797893b5990eaddef863d 105 Pfam PF12840 Helix-turn-helix domain 4 59 6.4E-14 T 13-10-2018 Astex_1033 a720da04f387ec645c3c6742580d4e07 520 Pfam PF09423 PhoD-like phosphatase 144 489 7.0E-99 T 13-10-2018 IPR018946 Alkaline phosphatase D-related Astex_1033 a720da04f387ec645c3c6742580d4e07 520 Gene3D G3DSA:3.60.21.70 135 520 5.1E-124 T 13-10-2018 IPR038607 PhoD-like superfamily Astex_1033 a720da04f387ec645c3c6742580d4e07 520 Gene3D G3DSA:2.60.40.380 25 134 1.2E-31 T 13-10-2018 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 Astex_1033 a720da04f387ec645c3c6742580d4e07 520 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 34 131 1.5E-28 T 13-10-2018 IPR032093 Phospholipase D, N-terminal Astex_1033 a720da04f387ec645c3c6742580d4e07 520 SUPERFAMILY SSF56300 141 494 9.17E-31 T 13-10-2018 Astex_3396 22897751634c0cb304978eb22a21ffd4 339 Gene3D G3DSA:3.10.310.10 143 315 1.2E-103 T 13-10-2018 Astex_3396 22897751634c0cb304978eb22a21ffd4 339 Pfam PF05544 Proline racemase 7 337 2.2E-111 T 13-10-2018 IPR008794 Proline racemase family Astex_3396 22897751634c0cb304978eb22a21ffd4 339 Gene3D G3DSA:3.10.310.10 6 337 1.2E-103 T 13-10-2018 Astex_3396 22897751634c0cb304978eb22a21ffd4 339 PIRSF PIRSF029792 1 339 4.6E-112 T 13-10-2018 IPR008794 Proline racemase family Astex_3396 22897751634c0cb304978eb22a21ffd4 339 SUPERFAMILY SSF54506 2 336 3.5E-102 T 13-10-2018 Astex_1144 3ca3d60eb369861897e32b7c1cc792b2 241 Pfam PF01966 HD domain 59 160 1.1E-12 T 13-10-2018 IPR006674 HD domain Astex_1144 3ca3d60eb369861897e32b7c1cc792b2 241 Gene3D G3DSA:1.10.3210.50 42 241 8.6E-65 T 13-10-2018 Astex_1144 3ca3d60eb369861897e32b7c1cc792b2 241 SUPERFAMILY SSF109604 50 241 3.4E-57 T 13-10-2018 Astex_1144 3ca3d60eb369861897e32b7c1cc792b2 241 SMART SM00471 53 170 3.5E-8 T 13-10-2018 IPR003607 HD/PDEase domain Astex_2528 135ff4a5a5f29a1faa68482a92048675 167 Gene3D G3DSA:1.10.3330.10 1 166 1.3E-59 T 13-10-2018 IPR036778 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase superfamily KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 Astex_2528 135ff4a5a5f29a1faa68482a92048675 167 Pfam PF09349 OHCU decarboxylase 5 162 2.3E-45 T 13-10-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 Astex_2528 135ff4a5a5f29a1faa68482a92048675 167 TIGRFAM TIGR03164 UHCUDC: OHCU decarboxylase 8 164 2.3E-55 T 13-10-2018 IPR017580 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase, type 1 GO:0019428 KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 Astex_2528 135ff4a5a5f29a1faa68482a92048675 167 SUPERFAMILY SSF158694 2 163 2.49E-51 T 13-10-2018 IPR036778 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase superfamily KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 Astex_2407 a9e9d2ffbfb3bb203675afde9893aadb 229 SUPERFAMILY SSF89562 21 181 1.96E-46 T 13-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily Astex_2407 a9e9d2ffbfb3bb203675afde9893aadb 229 Gene3D G3DSA:3.50.30.40 23 172 2.6E-51 T 13-10-2018 Astex_2407 a9e9d2ffbfb3bb203675afde9893aadb 229 Pfam PF03737 Aldolase/RraA 26 171 1.6E-39 T 13-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein Astex_2407 a9e9d2ffbfb3bb203675afde9893aadb 229 TIGRFAM TIGR02798 ligK_PcmE: 4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase 3 222 1.8E-103 T 13-10-2018 IPR014165 4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase KEGG: 00362+4.1.3.17|KEGG: 00660+4.1.3.17|MetaCyc: PWY-7701 Astex_2589 086fc7a662b9ae253cb3e6d789972743 501 Pfam PF16499 Alpha galactosidase A 149 415 2.9E-71 T 13-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Astex_2589 086fc7a662b9ae253cb3e6d789972743 501 SUPERFAMILY SSF51011 410 500 1.76E-19 T 13-10-2018 Astex_2589 086fc7a662b9ae253cb3e6d789972743 501 Gene3D G3DSA:3.20.20.70 143 416 5.8E-114 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_2589 086fc7a662b9ae253cb3e6d789972743 501 ProSitePatterns PS00512 Alpha-galactosidase signature. 185 200 - T 13-10-2018 IPR000111 Glycoside hydrolase family 27/36, conserved site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Astex_2589 086fc7a662b9ae253cb3e6d789972743 501 Gene3D G3DSA:2.60.40.1180 418 501 3.9E-22 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta Astex_2589 086fc7a662b9ae253cb3e6d789972743 501 PRINTS PR00740 Glycosyl hydrolase family 27 signature 180 195 8.6E-57 T 13-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Astex_2589 086fc7a662b9ae253cb3e6d789972743 501 PRINTS PR00740 Glycosyl hydrolase family 27 signature 218 239 8.6E-57 T 13-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Astex_2589 086fc7a662b9ae253cb3e6d789972743 501 PRINTS PR00740 Glycosyl hydrolase family 27 signature 284 302 8.6E-57 T 13-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Astex_2589 086fc7a662b9ae253cb3e6d789972743 501 PRINTS PR00740 Glycosyl hydrolase family 27 signature 350 369 8.6E-57 T 13-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Astex_2589 086fc7a662b9ae253cb3e6d789972743 501 PRINTS PR00740 Glycosyl hydrolase family 27 signature 144 163 8.6E-57 T 13-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Astex_2589 086fc7a662b9ae253cb3e6d789972743 501 PRINTS PR00740 Glycosyl hydrolase family 27 signature 252 269 8.6E-57 T 13-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Astex_2589 086fc7a662b9ae253cb3e6d789972743 501 PRINTS PR00740 Glycosyl hydrolase family 27 signature 371 392 8.6E-57 T 13-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 Astex_2589 086fc7a662b9ae253cb3e6d789972743 501 SUPERFAMILY SSF51445 140 415 2.18E-88 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_0956 481dd004977d57c180fd80ed57ddf153 104 SMART SM00739 4 31 4.6E-6 T 13-10-2018 IPR005824 KOW Astex_0956 481dd004977d57c180fd80ed57ddf153 104 Gene3D G3DSA:2.30.30.30 2 103 3.4E-37 T 13-10-2018 IPR014722 Ribosomal protein L2, domain 2 Astex_0956 481dd004977d57c180fd80ed57ddf153 104 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 3 102 1.5E-37 T 13-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0956 481dd004977d57c180fd80ed57ddf153 104 Pfam PF00467 KOW motif 7 37 4.3E-8 T 13-10-2018 IPR005824 KOW Astex_0956 481dd004977d57c180fd80ed57ddf153 104 SUPERFAMILY SSF50104 4 101 1.62E-33 T 13-10-2018 IPR008991 Translation protein SH3-like domain superfamily Astex_0956 481dd004977d57c180fd80ed57ddf153 104 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 40 102 2.0E-24 T 13-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0956 481dd004977d57c180fd80ed57ddf153 104 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 3 96 21.47 T 13-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0956 481dd004977d57c180fd80ed57ddf153 104 ProSitePatterns PS01108 Ribosomal protein L24 signature. 8 25 - T 13-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_2225 eeb7e4f82649764303bd7e51976a8483 688 Pfam PF13576 Pentapeptide repeats (9 copies) 266 313 1.1E-8 T 13-10-2018 IPR001646 Pentapeptide repeat Astex_2225 eeb7e4f82649764303bd7e51976a8483 688 Pfam PF13576 Pentapeptide repeats (9 copies) 344 390 7.4E-8 T 13-10-2018 IPR001646 Pentapeptide repeat Astex_2225 eeb7e4f82649764303bd7e51976a8483 688 Gene3D G3DSA:2.160.20.80 233 401 7.2E-7 T 13-10-2018 Astex_0548 81799918e4965b10205bc936c8141212 407 SUPERFAMILY SSF56935 32 281 1.22E-6 T 13-10-2018 Astex_0548 81799918e4965b10205bc936c8141212 407 Pfam PF13372 Alginate export 23 383 1.5E-67 T 13-10-2018 IPR025388 Alginate export domain Astex_0513 dbaacc66066b614f944e5d31b846234d 316 SUPERFAMILY SSF51197 22 276 2.06E-16 T 13-10-2018 Astex_0513 dbaacc66066b614f944e5d31b846234d 316 Gene3D G3DSA:2.60.120.650 21 231 6.1E-12 T 13-10-2018 Astex_1988 8d83b36dd94cfc3448b88ef2ba192cb0 499 PIRSF PIRSF011396 1 499 1.6E-186 T 13-10-2018 IPR033856 Flavin-dependent tryptophan halogenase Astex_1988 8d83b36dd94cfc3448b88ef2ba192cb0 499 Gene3D G3DSA:3.50.50.60 1 497 6.0E-181 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_1988 8d83b36dd94cfc3448b88ef2ba192cb0 499 Pfam PF04820 Tryptophan halogenase 7 463 5.2E-183 T 13-10-2018 IPR006905 Flavin-dependent halogenase Astex_1988 8d83b36dd94cfc3448b88ef2ba192cb0 499 SUPERFAMILY SSF51905 6 422 1.4E-28 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_3455 6f9d04396d055ea2f6cba46e33d7be62 169 Pfam PF14219 Domain of unknown function (DUF4328) 20 155 1.5E-19 T 13-10-2018 IPR025565 Domain of unknown function DUF4328 Astex_2155 b3efaeed9b79ec1b6e532057699ea048 216 SUPERFAMILY SSF49482 2 214 3.79E-35 T 13-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 Astex_2155 b3efaeed9b79ec1b6e532057699ea048 216 Pfam PF00775 Dioxygenase 45 120 5.5E-7 T 13-10-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 Astex_2155 b3efaeed9b79ec1b6e532057699ea048 216 Gene3D G3DSA:2.60.130.10 1 205 4.8E-30 T 13-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 Astex_2349 f1e7ca0be306290cd288101fa719f1a5 392 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 37 343 2.4E-27 T 13-10-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 Astex_2349 f1e7ca0be306290cd288101fa719f1a5 392 Gene3D G3DSA:3.20.20.80 27 355 4.3E-55 T 13-10-2018 Astex_2349 f1e7ca0be306290cd288101fa719f1a5 392 SUPERFAMILY SSF51445 24 354 2.15E-52 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_2721 1cbbe421a08cb28f2a400169f1ef9b50 510 SUPERFAMILY SSF51905 13 428 1.55E-30 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_2721 1cbbe421a08cb28f2a400169f1ef9b50 510 Pfam PF04820 Tryptophan halogenase 13 468 2.8E-182 T 13-10-2018 IPR006905 Flavin-dependent halogenase Astex_2721 1cbbe421a08cb28f2a400169f1ef9b50 510 Gene3D G3DSA:3.50.50.60 9 503 7.9E-186 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_2721 1cbbe421a08cb28f2a400169f1ef9b50 510 PIRSF PIRSF011396 7 505 2.9E-187 T 13-10-2018 IPR033856 Flavin-dependent tryptophan halogenase Astex_1724 257a7c226f86a31260fe314d001f9574 336 PRINTS PR00474 Glutamate 5-kinase family signature 235 262 6.1E-9 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 Astex_1724 257a7c226f86a31260fe314d001f9574 336 PRINTS PR00474 Glutamate 5-kinase family signature 285 305 6.1E-9 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 Astex_1724 257a7c226f86a31260fe314d001f9574 336 PRINTS PR00474 Glutamate 5-kinase family signature 90 104 6.1E-9 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 Astex_1724 257a7c226f86a31260fe314d001f9574 336 TIGRFAM TIGR00761 argB: acetylglutamate kinase 61 310 2.0E-70 T 13-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Astex_1724 257a7c226f86a31260fe314d001f9574 336 Pfam PF00696 Amino acid kinase family 60 311 6.5E-42 T 13-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 Astex_1724 257a7c226f86a31260fe314d001f9574 336 Gene3D G3DSA:3.40.1160.10 37 336 2.7E-86 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Astex_1724 257a7c226f86a31260fe314d001f9574 336 PIRSF PIRSF000728 43 335 1.6E-101 T 13-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Astex_1724 257a7c226f86a31260fe314d001f9574 336 SUPERFAMILY SSF53633 40 335 7.33E-82 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily Astex_1724 257a7c226f86a31260fe314d001f9574 336 Hamap MF_00082 Acetylglutamate kinase [argB]. 58 328 48.027 T 13-10-2018 IPR037528 Acetylglutamate kinase ArgB GO:0003991|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 Astex_3785 16b4cfb17e3d24dfbdd8eebc79ece024 236 Pfam PF06586 TraK protein 7 230 1.3E-44 T 13-10-2018 IPR010563 Pilus assembly TraK Astex_1181 eba77587cf338b75d13103c1d6fe66c4 118 SUPERFAMILY SSF142906 1 118 7.72E-31 T 13-10-2018 IPR038056 YjbR-like superfamily Astex_1181 eba77587cf338b75d13103c1d6fe66c4 118 Gene3D G3DSA:3.90.1150.30 1 117 8.7E-16 T 13-10-2018 IPR038056 YjbR-like superfamily Astex_1181 eba77587cf338b75d13103c1d6fe66c4 118 Pfam PF04237 YjbR 12 103 2.9E-16 T 13-10-2018 IPR007351 Uncharacterised protein YjbR Astex_0367 c810f65581e8c50da72a6154c1af1521 652 SUPERFAMILY SSF69318 130 596 1.14E-18 T 13-10-2018 Astex_0367 c810f65581e8c50da72a6154c1af1521 652 Gene3D G3DSA:2.60.40.10 27 115 5.1E-25 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_1749 500220f74abd5a83aa3acff5e6a321bd 117 Gene3D G3DSA:3.30.1330.70 10 116 6.1E-10 T 13-10-2018 IPR036614 Holliday junction resolvase RusA-like superfamily GO:0000287|GO:0006281|GO:0006310 Astex_1749 500220f74abd5a83aa3acff5e6a321bd 117 SUPERFAMILY SSF103084 14 114 5.49E-16 T 13-10-2018 IPR036614 Holliday junction resolvase RusA-like superfamily GO:0000287|GO:0006281|GO:0006310 Astex_1749 500220f74abd5a83aa3acff5e6a321bd 117 Pfam PF05866 Endodeoxyribonuclease RusA 69 112 1.7E-12 T 13-10-2018 IPR008822 Holliday junction resolvase RusA-like GO:0000287|GO:0006281|GO:0006310 Astex_3757 e255d6cd5fcc84a5222353b70c8ff8bf 141 SUPERFAMILY SSF50118 22 131 1.26E-12 T 13-10-2018 Astex_3757 e255d6cd5fcc84a5222353b70c8ff8bf 141 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 28 127 1.7E-14 T 13-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 Astex_3757 e255d6cd5fcc84a5222353b70c8ff8bf 141 Gene3D G3DSA:2.30.30.110 20 133 2.2E-8 T 13-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor Astex_0947 04f3b2e5210428ab4a5acb252209c3b9 98 Pfam PF00276 Ribosomal protein L23 9 94 2.8E-30 T 13-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 Astex_0947 04f3b2e5210428ab4a5acb252209c3b9 98 ProSitePatterns PS00050 Ribosomal protein L23 signature. 80 95 - T 13-10-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0947 04f3b2e5210428ab4a5acb252209c3b9 98 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 8 97 20.269 T 13-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 Astex_0947 04f3b2e5210428ab4a5acb252209c3b9 98 Gene3D G3DSA:3.30.70.330 6 97 1.3E-31 T 13-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily Astex_0947 04f3b2e5210428ab4a5acb252209c3b9 98 SUPERFAMILY SSF54189 7 96 1.29E-31 T 13-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_0110 4e538dc5fe6538a2247be8605c7cad65 217 Hamap MF_00494 Probable transaldolase [tal]. 1 214 44.255 T 13-10-2018 IPR022999 Transaldolase type 3B, putative GO:0004801 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 Astex_0110 4e538dc5fe6538a2247be8605c7cad65 217 TIGRFAM TIGR00875 fsa_talC_mipB: fructose-6-phosphate aldolase 1 210 2.5E-82 T 13-10-2018 IPR004731 Transaldolase type 3B/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 Astex_0110 4e538dc5fe6538a2247be8605c7cad65 217 Gene3D G3DSA:3.20.20.70 1 216 8.3E-83 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_0110 4e538dc5fe6538a2247be8605c7cad65 217 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 13-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 Astex_0110 4e538dc5fe6538a2247be8605c7cad65 217 SUPERFAMILY SSF51569 1 214 1.15E-74 T 13-10-2018 Astex_0110 4e538dc5fe6538a2247be8605c7cad65 217 ProSitePatterns PS00958 Transaldolase active site. 80 97 - T 13-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 Astex_0110 4e538dc5fe6538a2247be8605c7cad65 217 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 3 202 2.4E-55 T 13-10-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 Astex_2037 d24c8a15f233a94171e74a5d75f9fba8 160 Pfam PF13412 Winged helix-turn-helix DNA-binding 10 57 4.9E-21 T 13-10-2018 Astex_2037 d24c8a15f233a94171e74a5d75f9fba8 160 Gene3D G3DSA:3.30.70.920 64 147 2.9E-21 T 13-10-2018 Astex_2037 d24c8a15f233a94171e74a5d75f9fba8 160 SUPERFAMILY SSF46785 10 69 1.95E-19 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_2037 d24c8a15f233a94171e74a5d75f9fba8 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 37 56 5.5E-17 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 Astex_2037 d24c8a15f233a94171e74a5d75f9fba8 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 26 37 5.5E-17 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 Astex_2037 d24c8a15f233a94171e74a5d75f9fba8 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 10 26 5.5E-17 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 Astex_2037 d24c8a15f233a94171e74a5d75f9fba8 160 ProSitePatterns PS00519 AsnC-type HTH domain signature. 28 54 - T 13-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site Astex_2037 d24c8a15f233a94171e74a5d75f9fba8 160 SMART SM00344 10 119 1.7E-44 T 13-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 Astex_2037 d24c8a15f233a94171e74a5d75f9fba8 160 Pfam PF01037 Lrp/AsnC ligand binding domain 76 149 1.4E-19 T 13-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain Astex_2037 d24c8a15f233a94171e74a5d75f9fba8 160 SUPERFAMILY SSF54909 73 154 7.78E-19 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel Astex_2037 d24c8a15f233a94171e74a5d75f9fba8 160 Gene3D G3DSA:1.10.10.10 1 63 8.9E-26 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_3009 6d76e43dae2ab4184be454d98058e7fd 216 TIGRFAM TIGR00667 aat: leucyl/phenylalanyl-tRNA--protein transferase 10 192 9.4E-56 T 13-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 Astex_3009 6d76e43dae2ab4184be454d98058e7fd 216 SUPERFAMILY SSF55729 4 197 1.91E-68 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Astex_3009 6d76e43dae2ab4184be454d98058e7fd 216 Pfam PF03588 Leucyl/phenylalanyl-tRNA protein transferase 7 178 4.3E-63 T 13-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 Astex_3009 6d76e43dae2ab4184be454d98058e7fd 216 Gene3D G3DSA:3.40.630.70 35 209 7.1E-58 T 13-10-2018 Astex_3009 6d76e43dae2ab4184be454d98058e7fd 216 Hamap MF_00688 Leucyl/phenylalanyl-tRNA--protein transferase [aat]. 1 216 73.696 T 13-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 Astex_0953 360926ed56e2949c85ccb9117c087dab 64 SUPERFAMILY SSF46561 2 61 7.33E-22 T 13-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0953 360926ed56e2949c85ccb9117c087dab 64 TIGRFAM TIGR00012 L29: ribosomal protein uL29 6 59 2.1E-23 T 13-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0953 360926ed56e2949c85ccb9117c087dab 64 ProSitePatterns PS00579 Ribosomal protein L29 signature. 40 54 - T 13-10-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0953 360926ed56e2949c85ccb9117c087dab 64 Gene3D G3DSA:1.10.287.310 2 64 2.3E-26 T 13-10-2018 Astex_0953 360926ed56e2949c85ccb9117c087dab 64 Pfam PF00831 Ribosomal L29 protein 6 59 1.2E-24 T 13-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0953 360926ed56e2949c85ccb9117c087dab 64 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 2 61 17.451 T 13-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_2570 53846bcf55812ddb7a09e6a21cb6931b 116 SUPERFAMILY SSF142906 1 109 2.62E-9 T 13-10-2018 IPR038056 YjbR-like superfamily Astex_2570 53846bcf55812ddb7a09e6a21cb6931b 116 Pfam PF04237 YjbR 12 98 5.2E-13 T 13-10-2018 IPR007351 Uncharacterised protein YjbR Astex_2379 8b925fd1c19e026a5875c4d5602ad692 306 SUPERFAMILY SSF51430 4 264 5.89E-29 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily Astex_2379 8b925fd1c19e026a5875c4d5602ad692 306 Pfam PF00248 Aldo/keto reductase family 5 263 7.7E-20 T 13-10-2018 IPR023210 NADP-dependent oxidoreductase domain Astex_2379 8b925fd1c19e026a5875c4d5602ad692 306 Gene3D G3DSA:3.20.20.100 1 269 2.1E-24 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily Astex_2445 032ff1896f09132c38aa725d7358b428 606 SUPERFAMILY SSF56235 91 191 4.98E-10 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Astex_2445 032ff1896f09132c38aa725d7358b428 606 Pfam PF00733 Asparagine synthase 233 387 4.8E-11 T 13-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 Astex_2445 032ff1896f09132c38aa725d7358b428 606 Pfam PF00733 Asparagine synthase 461 551 3.0E-8 T 13-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 Astex_2445 032ff1896f09132c38aa725d7358b428 606 Gene3D G3DSA:3.60.20.10 70 197 2.1E-7 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Astex_2445 032ff1896f09132c38aa725d7358b428 606 SUPERFAMILY SSF52402 201 554 1.26E-22 T 13-10-2018 Astex_2445 032ff1896f09132c38aa725d7358b428 606 Gene3D G3DSA:3.40.50.620 205 396 1.8E-14 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Astex_0515 d53f79eb87fa674de709a452fff27347 377 SUPERFAMILY SSF55729 143 304 1.77E-15 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Astex_0515 d53f79eb87fa674de709a452fff27347 377 Pfam PF13480 Acetyltransferase (GNAT) domain 148 295 4.2E-30 T 13-10-2018 IPR038740 BioF2-like, acetyltransferase domain KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 Astex_2623 81f7c1bb0cbfc7ff5d0b44daedb0328f 426 Pfam PF00675 Insulinase (Peptidase family M16) 29 168 6.9E-29 T 13-10-2018 IPR011765 Peptidase M16, N-terminal Astex_2623 81f7c1bb0cbfc7ff5d0b44daedb0328f 426 SUPERFAMILY SSF63411 233 412 1.07E-39 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 Astex_2623 81f7c1bb0cbfc7ff5d0b44daedb0328f 426 Pfam PF05193 Peptidase M16 inactive domain 178 345 1.1E-30 T 13-10-2018 IPR007863 Peptidase M16, C-terminal Astex_2623 81f7c1bb0cbfc7ff5d0b44daedb0328f 426 SUPERFAMILY SSF63411 8 220 9.78E-51 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 Astex_2623 81f7c1bb0cbfc7ff5d0b44daedb0328f 426 Gene3D G3DSA:3.30.830.10 228 420 8.2E-50 T 13-10-2018 Astex_2623 81f7c1bb0cbfc7ff5d0b44daedb0328f 426 Gene3D G3DSA:3.30.830.10 12 219 2.6E-54 T 13-10-2018 Astex_3438 1eba67caa67ab9eef1743e3b16b44b76 486 TIGRFAM TIGR02745 ccoG_rdxA_fixG: cytochrome c oxidase accessory protein CcoG 19 464 1.8E-154 T 13-10-2018 IPR014116 Cytochrome c oxidase cbb3 type, accessory protein FixG GO:0016021|GO:0055114 Astex_3438 1eba67caa67ab9eef1743e3b16b44b76 486 Gene3D G3DSA:2.60.40.10 359 485 1.9E-12 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_3438 1eba67caa67ab9eef1743e3b16b44b76 486 SUPERFAMILY SSF54862 88 311 1.17E-27 T 13-10-2018 Astex_3438 1eba67caa67ab9eef1743e3b16b44b76 486 Pfam PF12801 4Fe-4S binding domain 80 116 2.8E-10 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Astex_3438 1eba67caa67ab9eef1743e3b16b44b76 486 Pfam PF13746 4Fe-4S dicluster domain 202 305 2.1E-42 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Astex_3438 1eba67caa67ab9eef1743e3b16b44b76 486 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 253 264 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Astex_3438 1eba67caa67ab9eef1743e3b16b44b76 486 Pfam PF11614 IG-like fold at C-terminal of FixG, putative oxidoreductase 357 484 5.8E-22 T 13-10-2018 IPR032879 FixG, C-terminal immunoglobulin-like domain Astex_1251 27206e8b39eda4870e884e3e95038590 370 Pfam PF02119 Flagellar P-ring protein 29 369 9.5E-132 T 13-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 Astex_1251 27206e8b39eda4870e884e3e95038590 370 PRINTS PR01010 Flagellar P-ring protein signature 44 59 1.4E-77 T 13-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 Astex_1251 27206e8b39eda4870e884e3e95038590 370 PRINTS PR01010 Flagellar P-ring protein signature 64 79 1.4E-77 T 13-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 Astex_1251 27206e8b39eda4870e884e3e95038590 370 PRINTS PR01010 Flagellar P-ring protein signature 111 128 1.4E-77 T 13-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 Astex_1251 27206e8b39eda4870e884e3e95038590 370 PRINTS PR01010 Flagellar P-ring protein signature 195 213 1.4E-77 T 13-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 Astex_1251 27206e8b39eda4870e884e3e95038590 370 PRINTS PR01010 Flagellar P-ring protein signature 29 44 1.4E-77 T 13-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 Astex_1251 27206e8b39eda4870e884e3e95038590 370 PRINTS PR01010 Flagellar P-ring protein signature 169 187 1.4E-77 T 13-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 Astex_1251 27206e8b39eda4870e884e3e95038590 370 PRINTS PR01010 Flagellar P-ring protein signature 128 146 1.4E-77 T 13-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 Astex_1251 27206e8b39eda4870e884e3e95038590 370 PRINTS PR01010 Flagellar P-ring protein signature 89 108 1.4E-77 T 13-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 Astex_1251 27206e8b39eda4870e884e3e95038590 370 PRINTS PR01010 Flagellar P-ring protein signature 256 268 1.4E-77 T 13-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 Astex_1251 27206e8b39eda4870e884e3e95038590 370 Hamap MF_00416 Flagellar P-ring protein [flgI]. 3 370 35.643 T 13-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 Astex_1314 840e317c36f65b2037b21129686f297e 774 Pfam PF07944 Beta-L-arabinofuranosidase, GH127 40 547 7.1E-141 T 13-10-2018 IPR012878 Beta-L-arabinofuranosidase, GH127 Astex_1314 840e317c36f65b2037b21129686f297e 774 SUPERFAMILY SSF48208 85 391 3.66E-9 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 Astex_1964 26311548b2376ffedd29d8c7cab4e37f 204 Gene3D G3DSA:1.10.10.10 94 181 7.2E-18 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1964 26311548b2376ffedd29d8c7cab4e37f 204 Gene3D G3DSA:1.10.1740.10 4 93 9.3E-22 T 13-10-2018 Astex_1964 26311548b2376ffedd29d8c7cab4e37f 204 Pfam PF08281 Sigma-70, region 4 121 173 5.1E-13 T 13-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 Astex_1964 26311548b2376ffedd29d8c7cab4e37f 204 Pfam PF04542 Sigma-70 region 2 26 93 9.0E-20 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 Astex_1964 26311548b2376ffedd29d8c7cab4e37f 204 SUPERFAMILY SSF88659 97 179 1.51E-15 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Astex_1964 26311548b2376ffedd29d8c7cab4e37f 204 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 24 177 9.3E-30 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 Astex_1964 26311548b2376ffedd29d8c7cab4e37f 204 SUPERFAMILY SSF88946 7 104 7.22E-24 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 Astex_0833 4bcb57a34d89c34371dd6af8253d3a0e 612 Gene3D G3DSA:1.20.1560.10 11 355 7.2E-29 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Astex_0833 4bcb57a34d89c34371dd6af8253d3a0e 612 ProSitePatterns PS00211 ABC transporters family signature. 507 521 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Astex_0833 4bcb57a34d89c34371dd6af8253d3a0e 612 SUPERFAMILY SSF90123 32 343 7.19E-47 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 Astex_0833 4bcb57a34d89c34371dd6af8253d3a0e 612 SMART SM00382 390 581 5.7E-20 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_0833 4bcb57a34d89c34371dd6af8253d3a0e 612 Pfam PF00664 ABC transporter transmembrane region 49 308 9.2E-17 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 Astex_0833 4bcb57a34d89c34371dd6af8253d3a0e 612 Gene3D G3DSA:3.40.50.300 356 608 9.9E-92 T 13-10-2018 Astex_0833 4bcb57a34d89c34371dd6af8253d3a0e 612 SUPERFAMILY SSF52540 355 605 7.94E-88 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0833 4bcb57a34d89c34371dd6af8253d3a0e 612 Pfam PF00005 ABC transporter 381 535 8.3E-35 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_3670 e7b7d0ba0bebb068a2f53a3e15892be6 446 Gene3D G3DSA:1.20.1250.20 244 442 4.0E-36 T 13-10-2018 Astex_3670 e7b7d0ba0bebb068a2f53a3e15892be6 446 TIGRFAM TIGR00893 2A0114: D-galactonate transporter 31 432 5.6E-128 T 13-10-2018 Astex_3670 e7b7d0ba0bebb068a2f53a3e15892be6 446 Pfam PF07690 Major Facilitator Superfamily 29 316 3.2E-46 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Astex_3670 e7b7d0ba0bebb068a2f53a3e15892be6 446 PIRSF PIRSF002808 2 445 1.4E-41 T 13-10-2018 IPR000849 Sugar phosphate transporter GO:0016021|GO:0022857|GO:0055085 Astex_3670 e7b7d0ba0bebb068a2f53a3e15892be6 446 SUPERFAMILY SSF103473 13 438 2.62E-78 T 13-10-2018 IPR036259 MFS transporter superfamily Astex_3670 e7b7d0ba0bebb068a2f53a3e15892be6 446 Gene3D G3DSA:1.20.1250.20 16 215 2.0E-42 T 13-10-2018 Astex_2081 d1e47f2da5036a338d925730e57694ad 44 Gene3D G3DSA:3.30.160.390 7 44 1.7E-7 T 13-10-2018 IPR038488 Integrase, DNA-binding domain superfamily Astex_3803 93ec370a1151c0b17b0eacc40daaca63 68 SUPERFAMILY SSF47413 2 65 1.39E-18 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Astex_3803 93ec370a1151c0b17b0eacc40daaca63 68 Pfam PF01381 Helix-turn-helix 6 60 8.6E-18 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Astex_3803 93ec370a1151c0b17b0eacc40daaca63 68 SMART SM00530 5 60 2.8E-16 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Astex_3803 93ec370a1151c0b17b0eacc40daaca63 68 Gene3D G3DSA:1.10.260.40 1 65 1.6E-21 T 13-10-2018 Astex_0733 f2488aa67a2e113ff526c3fa6edd9e00 193 Pfam PF03232 Ubiquinone biosynthesis protein COQ7 12 177 7.1E-42 T 13-10-2018 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 Reactome: R-HSA-2142789 Astex_0733 f2488aa67a2e113ff526c3fa6edd9e00 193 SUPERFAMILY SSF47240 12 149 3.75E-13 T 13-10-2018 IPR009078 Ferritin-like superfamily Astex_3731 ad13586aad637dfffd056048bee1632f 1481 Gene3D G3DSA:2.180.10.10 1016 1248 9.5E-26 T 13-10-2018 Astex_3731 ad13586aad637dfffd056048bee1632f 1481 Pfam PF05593 RHS Repeat 897 930 1.3E-6 T 13-10-2018 IPR031325 RHS repeat Astex_3731 ad13586aad637dfffd056048bee1632f 1481 Pfam PF05593 RHS Repeat 769 794 7.9E-6 T 13-10-2018 IPR031325 RHS repeat Astex_3731 ad13586aad637dfffd056048bee1632f 1481 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1175 1248 7.6E-22 T 13-10-2018 IPR022385 Rhs repeat-associated core GO:0097264 Astex_3731 ad13586aad637dfffd056048bee1632f 1481 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 771 794 0.0016 T 13-10-2018 IPR006530 YD repeat Astex_1463 da33ac69321aece9720adea21bb038c0 1112 Gene3D G3DSA:2.170.130.10 48 185 4.7E-30 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_1463 da33ac69321aece9720adea21bb038c0 1112 Pfam PF00593 TonB dependent receptor 629 1111 7.5E-29 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_1463 da33ac69321aece9720adea21bb038c0 1112 Pfam PF07715 TonB-dependent Receptor Plug Domain 66 181 2.5E-15 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_1463 da33ac69321aece9720adea21bb038c0 1112 SUPERFAMILY SSF56935 52 1111 4.88E-67 T 13-10-2018 Astex_0031 d842a2c3f37d233b3f7e00e0bb547807 137 SUPERFAMILY SSF47413 48 106 4.44E-8 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Astex_0031 d842a2c3f37d233b3f7e00e0bb547807 137 Gene3D G3DSA:1.10.260.40 45 119 1.1E-13 T 13-10-2018 Astex_0659 03f94b0728f8f90438bb897054ee5c91 30 Pfam PF09604 F subunit of K+-transporting ATPase (Potass_KdpF) 6 27 7.4E-7 T 13-10-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 Astex_0659 03f94b0728f8f90438bb897054ee5c91 30 TIGRFAM TIGR02115 potass_kdpF: K+-transporting ATPase, F subunit 6 29 3.9E-8 T 13-10-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 Astex_2063 e54c9c798b9597df704787efe66350bc 148 Pfam PF07883 Cupin domain 53 117 4.6E-11 T 13-10-2018 IPR013096 Cupin 2, conserved barrel Astex_2063 e54c9c798b9597df704787efe66350bc 148 Gene3D G3DSA:2.60.120.10 13 142 3.2E-47 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Astex_2063 e54c9c798b9597df704787efe66350bc 148 SUPERFAMILY SSF51182 19 141 1.54E-30 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily Astex_3469 f68405c7b2e4330e5301e6408968147e 192 SUPERFAMILY SSF52141 4 187 5.23E-47 T 13-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Astex_3469 f68405c7b2e4330e5301e6408968147e 192 Gene3D G3DSA:3.40.470.10 2 190 9.3E-58 T 13-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Astex_3469 f68405c7b2e4330e5301e6408968147e 192 Pfam PF03167 Uracil DNA glycosylase superfamily 28 184 1.2E-20 T 13-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Astex_3469 f68405c7b2e4330e5301e6408968147e 192 SMART SM00986 25 184 8.2E-29 T 13-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Astex_3469 f68405c7b2e4330e5301e6408968147e 192 SMART SM00987 25 184 8.2E-29 T 13-10-2018 Astex_1937 f9fcf2e44733644415d079bef6ccfd7c 78 SUPERFAMILY SSF50037 3 76 1.68E-13 T 13-10-2018 IPR008988 Transcriptional repressor, C-terminal Astex_1937 f9fcf2e44733644415d079bef6ccfd7c 78 Gene3D G3DSA:2.30.30.90 1 78 1.2E-24 T 13-10-2018 IPR038157 Ferrous iron transporter, core domain Astex_1937 f9fcf2e44733644415d079bef6ccfd7c 78 SMART SM00899 1 77 3.7E-19 T 13-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 Astex_1937 f9fcf2e44733644415d079bef6ccfd7c 78 Pfam PF04023 FeoA domain 1 76 7.8E-19 T 13-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 Astex_3087 891896fd4449cc0a7ec8b262855193a0 228 Pfam PF01551 Peptidase family M23 92 189 6.0E-14 T 13-10-2018 IPR016047 Peptidase M23 Astex_3087 891896fd4449cc0a7ec8b262855193a0 228 Gene3D G3DSA:2.70.70.10 79 196 9.2E-16 T 13-10-2018 IPR011055 Duplicated hybrid motif Astex_3087 891896fd4449cc0a7ec8b262855193a0 228 SUPERFAMILY SSF51261 88 191 1.57E-14 T 13-10-2018 IPR011055 Duplicated hybrid motif Astex_1165 a42f9ab02a2958a43196bc11d046e533 354 SUPERFAMILY SSF51430 13 328 3.4E-88 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily Astex_1165 a42f9ab02a2958a43196bc11d046e533 354 Gene3D G3DSA:3.20.20.100 15 336 1.7E-112 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily Astex_1165 a42f9ab02a2958a43196bc11d046e533 354 Pfam PF00248 Aldo/keto reductase family 28 326 8.3E-69 T 13-10-2018 IPR023210 NADP-dependent oxidoreductase domain Astex_3576 e50f85d99c4ecbcda2854043a1af58db 638 Pfam PF09863 Uncharacterized protein conserved in bacteria (DUF2090) 328 632 1.9E-119 T 13-10-2018 IPR018659 Protein of unknown function DUF2090 Astex_3576 e50f85d99c4ecbcda2854043a1af58db 638 Gene3D G3DSA:3.20.20.70 353 636 6.0E-50 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_3576 e50f85d99c4ecbcda2854043a1af58db 638 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 277 290 - T 13-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 Astex_3576 e50f85d99c4ecbcda2854043a1af58db 638 SUPERFAMILY SSF53613 9 333 4.21E-72 T 13-10-2018 IPR029056 Ribokinase-like Astex_3576 e50f85d99c4ecbcda2854043a1af58db 638 TIGRFAM TIGR04382 myo_inos_iolC_N: 5-dehydro-2-deoxygluconokinase 9 333 1.4E-116 T 13-10-2018 IPR030830 5-Dehydro-2-deoxygluconokinase KEGG: 00562+2.7.1.92 Astex_3576 e50f85d99c4ecbcda2854043a1af58db 638 Pfam PF00294 pfkB family carbohydrate kinase 11 325 3.5E-47 T 13-10-2018 IPR011611 Carbohydrate kinase PfkB Astex_3576 e50f85d99c4ecbcda2854043a1af58db 638 Gene3D G3DSA:3.40.1190.20 12 315 3.5E-90 T 13-10-2018 IPR029056 Ribokinase-like Astex_3576 e50f85d99c4ecbcda2854043a1af58db 638 Gene3D G3DSA:2.20.150.10 17 112 3.5E-90 T 13-10-2018 IPR023314 5-Dehydro-2-deoxygluconokinase-like superfamily KEGG: 00562+2.7.1.92 Astex_1115 e00dc43c39ee747c3731d39017c348ad 74 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 19 72 2.8E-13 T 13-10-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 Astex_1115 e00dc43c39ee747c3731d39017c348ad 74 PRINTS PR00124 ATP synthase C subunit signature 47 72 3.0E-21 T 13-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_1115 e00dc43c39ee747c3731d39017c348ad 74 PRINTS PR00124 ATP synthase C subunit signature 30 45 3.0E-21 T 13-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_1115 e00dc43c39ee747c3731d39017c348ad 74 PRINTS PR00124 ATP synthase C subunit signature 9 28 3.0E-21 T 13-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_1115 e00dc43c39ee747c3731d39017c348ad 74 SUPERFAMILY SSF81333 5 72 3.92E-18 T 13-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily Astex_1115 e00dc43c39ee747c3731d39017c348ad 74 Gene3D G3DSA:1.20.20.10 3 74 2.8E-22 T 13-10-2018 IPR038662 F1F0 ATP synthase subunit C superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_1115 e00dc43c39ee747c3731d39017c348ad 74 Pfam PF00137 ATP synthase subunit C 9 71 3.6E-12 T 13-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 Astex_1115 e00dc43c39ee747c3731d39017c348ad 74 Hamap MF_01396 ATP synthase subunit c [atpH]. 4 72 14.83 T 13-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 Astex_2343 77e567c49f1b811ba1155d752f8aae89 404 SUPERFAMILY SSF52151 90 347 9.42E-27 T 13-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase Astex_2343 77e567c49f1b811ba1155d752f8aae89 404 Gene3D G3DSA:3.40.1090.10 74 199 1.1E-14 T 13-10-2018 Astex_2343 77e567c49f1b811ba1155d752f8aae89 404 Pfam PF01734 Patatin-like phospholipase 91 284 6.5E-13 T 13-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 Astex_0509 13941f50b078e77884d2ab428d49c164 483 SMART SM00283 39 280 2.5E-14 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_0509 13941f50b078e77884d2ab428d49c164 483 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 91 208 1.0E-23 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_0509 13941f50b078e77884d2ab428d49c164 483 Gene3D G3DSA:1.10.287.950 12 334 6.6E-38 T 13-10-2018 Astex_0509 13941f50b078e77884d2ab428d49c164 483 SUPERFAMILY SSF58104 33 295 5.49E-39 T 13-10-2018 Astex_0961 521553a94ffeda58a0e839a444bdee53 117 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 4 117 28.009 T 13-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_0961 521553a94ffeda58a0e839a444bdee53 117 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 6 117 4.7E-42 T 13-10-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0961 521553a94ffeda58a0e839a444bdee53 117 Gene3D G3DSA:3.30.420.100 4 117 1.7E-41 T 13-10-2018 Astex_0961 521553a94ffeda58a0e839a444bdee53 117 SUPERFAMILY SSF53137 10 115 3.27E-46 T 13-10-2018 Astex_0961 521553a94ffeda58a0e839a444bdee53 117 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 7 117 1.2E-42 T 13-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_2146 b3d16313eea0b8f028960864e6098d79 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 161 5.5E-26 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2146 b3d16313eea0b8f028960864e6098d79 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 228 248 5.5E-26 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2146 b3d16313eea0b8f028960864e6098d79 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 26 43 5.5E-26 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2146 b3d16313eea0b8f028960864e6098d79 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 209 5.5E-26 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2146 b3d16313eea0b8f028960864e6098d79 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 190 5.5E-26 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2146 b3d16313eea0b8f028960864e6098d79 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 98 109 5.5E-26 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2146 b3d16313eea0b8f028960864e6098d79 266 SUPERFAMILY SSF51735 24 265 2.54E-62 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_2146 b3d16313eea0b8f028960864e6098d79 266 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 25 211 2.8E-7 T 13-10-2018 Astex_2146 b3d16313eea0b8f028960864e6098d79 266 Gene3D G3DSA:3.40.50.720 13 266 6.1E-63 T 13-10-2018 Astex_2146 b3d16313eea0b8f028960864e6098d79 266 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 31 264 8.8E-46 T 13-10-2018 Astex_3683 f6dee65480f66b694210872b92e449ca 693 SUPERFAMILY SSF48208 307 487 4.03E-6 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 Astex_0730 a80bf09d0c99c4c9c9bb1d697b87d293 360 Gene3D G3DSA:3.40.50.300 52 259 4.0E-23 T 13-10-2018 Astex_0730 a80bf09d0c99c4c9c9bb1d697b87d293 360 Pfam PF07728 AAA domain (dynein-related subfamily) 79 217 8.8E-33 T 13-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 Astex_0730 a80bf09d0c99c4c9c9bb1d697b87d293 360 SUPERFAMILY SSF52540 57 258 6.78E-21 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_3625 7ac98e0eaeaa4445a9c0ac7d86d476cc 411 SUPERFAMILY SSF88659 103 162 1.73E-5 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like Astex_3625 7ac98e0eaeaa4445a9c0ac7d86d476cc 411 Pfam PF04542 Sigma-70 region 2 16 77 1.3E-8 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 Astex_3625 7ac98e0eaeaa4445a9c0ac7d86d476cc 411 Gene3D G3DSA:1.10.1740.10 1 74 1.7E-7 T 13-10-2018 Astex_3625 7ac98e0eaeaa4445a9c0ac7d86d476cc 411 SUPERFAMILY SSF88946 3 91 7.06E-12 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 Astex_3645 e52acd80248531cf56f33ba0688edfcf 269 PIRSF PIRSF006487 104 264 8.3E-9 T 13-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 Astex_3645 e52acd80248531cf56f33ba0688edfcf 269 TIGRFAM TIGR03425 urea_degr_2: urea carboxylase-associated protein 2 40 268 2.1E-89 T 13-10-2018 IPR017792 Urea carboxylase-associated protein 2 Astex_3645 e52acd80248531cf56f33ba0688edfcf 269 Pfam PF09347 Domain of unknown function (DUF1989) 45 212 3.5E-47 T 13-10-2018 IPR018959 Protein of unknown function DUF1989 Astex_1388 f3e9c0f4a3f17387b60247b4f1250e4c 318 Gene3D G3DSA:3.55.50.30 244 318 2.0E-5 T 13-10-2018 Astex_1388 f3e9c0f4a3f17387b60247b4f1250e4c 318 PIRSF PIRSF018266 10 318 4.3E-68 T 13-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component Astex_1388 f3e9c0f4a3f17387b60247b4f1250e4c 318 Pfam PF16344 Domain of unknown function (DUF4974) 217 314 1.4E-7 T 13-10-2018 IPR032508 Protein FecR, C-terminal Astex_1388 f3e9c0f4a3f17387b60247b4f1250e4c 318 Pfam PF04773 FecR protein 110 202 8.7E-21 T 13-10-2018 IPR006860 FecR protein Astex_1388 f3e9c0f4a3f17387b60247b4f1250e4c 318 Gene3D G3DSA:2.60.120.1440 103 237 8.6E-29 T 13-10-2018 Astex_3359 09467cfaf141efc8a126929c1f43f5d5 309 Pfam PF10134 Replication initiator protein A 23 256 9.3E-83 T 13-10-2018 IPR018777 Replication initiator protein A Astex_3318 acfdd7163808059579f39afc1470ae8d 341 Pfam PF00756 Putative esterase 47 301 5.6E-27 T 13-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 Astex_3318 acfdd7163808059579f39afc1470ae8d 341 SUPERFAMILY SSF53474 23 333 3.02E-40 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_3142 fa8a9613ade4edcdee2b941a05422b75 122 SMART SM00448 4 117 1.3E-33 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_3142 fa8a9613ade4edcdee2b941a05422b75 122 SUPERFAMILY SSF52172 1 122 4.55E-36 T 13-10-2018 IPR011006 CheY-like superfamily Astex_3142 fa8a9613ade4edcdee2b941a05422b75 122 Pfam PF00072 Response regulator receiver domain 6 117 7.7E-26 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_3142 fa8a9613ade4edcdee2b941a05422b75 122 Gene3D G3DSA:3.40.50.12740 3 122 7.6E-42 T 13-10-2018 Astex_0873 395c03461eb5b27c52203df8d1f7e7f6 407 Gene3D G3DSA:3.30.1330.60 289 405 3.4E-27 T 13-10-2018 IPR036737 OmpA-like domain superfamily Astex_0873 395c03461eb5b27c52203df8d1f7e7f6 407 SUPERFAMILY SSF103088 276 403 2.88E-28 T 13-10-2018 IPR036737 OmpA-like domain superfamily Astex_0873 395c03461eb5b27c52203df8d1f7e7f6 407 Pfam PF00691 OmpA family 304 399 6.5E-18 T 13-10-2018 IPR006665 OmpA-like domain Astex_0873 395c03461eb5b27c52203df8d1f7e7f6 407 ProSitePatterns PS01068 OmpA-like domain. 337 381 - T 13-10-2018 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 Astex_0873 395c03461eb5b27c52203df8d1f7e7f6 407 Pfam PF13505 Outer membrane protein beta-barrel domain 9 259 1.2E-15 T 13-10-2018 IPR027385 Outer membrane protein beta-barrel Astex_0873 395c03461eb5b27c52203df8d1f7e7f6 407 SUPERFAMILY SSF56925 24 259 1.18E-26 T 13-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel Astex_0873 395c03461eb5b27c52203df8d1f7e7f6 407 PRINTS PR01021 OMPA domain signature 350 366 2.7E-14 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 Astex_0873 395c03461eb5b27c52203df8d1f7e7f6 407 PRINTS PR01021 OMPA domain signature 305 327 2.7E-14 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 Astex_0873 395c03461eb5b27c52203df8d1f7e7f6 407 PRINTS PR01021 OMPA domain signature 335 350 2.7E-14 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 Astex_1091 efb76ab9717a38a2a4fc5d45ef091f93 169 Pfam PF02559 CarD-like/TRCF domain 10 118 4.6E-17 T 13-10-2018 IPR003711 CarD-like/TRCF domain Astex_1091 efb76ab9717a38a2a4fc5d45ef091f93 169 Gene3D G3DSA:1.20.58.1290 72 165 2.7E-24 T 13-10-2018 Astex_1091 efb76ab9717a38a2a4fc5d45ef091f93 169 SMART SM01058 9 119 1.1E-32 T 13-10-2018 IPR003711 CarD-like/TRCF domain Astex_1091 efb76ab9717a38a2a4fc5d45ef091f93 169 SUPERFAMILY SSF141259 7 69 1.29E-14 T 13-10-2018 IPR036101 CarD-like/TRCF domain superfamily Astex_1091 efb76ab9717a38a2a4fc5d45ef091f93 169 Gene3D G3DSA:2.30.30.840 1 71 3.3E-25 T 13-10-2018 Astex_3646 265ed6b3f23bde92ae1c4ca7c716ccf3 169 SUPERFAMILY SSF47598 9 51 3.34E-6 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 Astex_3646 265ed6b3f23bde92ae1c4ca7c716ccf3 169 Gene3D G3DSA:3.30.70.1150 58 142 1.8E-18 T 13-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal Astex_3646 265ed6b3f23bde92ae1c4ca7c716ccf3 169 Pfam PF08753 NikR C terminal nickel binding domain 62 138 2.5E-18 T 13-10-2018 IPR014864 Transcription factor, NikR, nickel binding C-terminal Astex_3646 265ed6b3f23bde92ae1c4ca7c716ccf3 169 Gene3D G3DSA:1.10.1220.10 16 52 5.5E-8 T 13-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 Astex_3646 265ed6b3f23bde92ae1c4ca7c716ccf3 169 SUPERFAMILY SSF55021 61 138 4.88E-16 T 13-10-2018 Astex_1383 13974dc388a34a6a5cefe46fd97fffd6 327 SUPERFAMILY SSF51126 39 326 5.5E-72 T 13-10-2018 IPR011050 Pectin lyase fold/virulence factor Astex_1383 13974dc388a34a6a5cefe46fd97fffd6 327 Gene3D G3DSA:2.160.20.10 31 327 3.0E-91 T 13-10-2018 IPR012334 Pectin lyase fold Astex_1383 13974dc388a34a6a5cefe46fd97fffd6 327 Pfam PF01095 Pectinesterase 39 310 9.5E-58 T 13-10-2018 IPR000070 Pectinesterase, catalytic GO:0005618|GO:0030599|GO:0042545 KEGG: 00040+3.1.1.11|MetaCyc: PWY-1081|MetaCyc: PWY-7246|MetaCyc: PWY-7248 Astex_1094 10cd414c493087d6c13f7b607c1f2a53 358 Pfam PF01699 Sodium/calcium exchanger protein 213 355 1.1E-8 T 13-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 Astex_1094 10cd414c493087d6c13f7b607c1f2a53 358 Pfam PF01699 Sodium/calcium exchanger protein 38 185 3.6E-13 T 13-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 Astex_0726 9aa31bf7d44ad30ac979501a6a5a4719 466 Gene3D G3DSA:3.20.20.70 97 313 1.5E-32 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_0726 9aa31bf7d44ad30ac979501a6a5a4719 466 Pfam PF13394 4Fe-4S single cluster domain 103 182 7.4E-7 T 13-10-2018 Astex_0726 9aa31bf7d44ad30ac979501a6a5a4719 466 SUPERFAMILY SSF102114 85 303 2.09E-37 T 13-10-2018 Astex_0726 9aa31bf7d44ad30ac979501a6a5a4719 466 Pfam PF04055 Radical SAM superfamily 101 260 2.3E-19 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Astex_3618 ecf107cb1bd9fb357786235642f99e74 1003 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 43 1003 1.8E-179 T 13-10-2018 IPR010104 Bacterial TonB-dependent receptor Astex_3618 ecf107cb1bd9fb357786235642f99e74 1003 Gene3D G3DSA:2.40.170.20 596 1003 1.6E-37 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_3618 ecf107cb1bd9fb357786235642f99e74 1003 SUPERFAMILY SSF56935 27 1003 3.36E-67 T 13-10-2018 Astex_3618 ecf107cb1bd9fb357786235642f99e74 1003 Gene3D G3DSA:2.170.130.10 31 170 1.4E-10 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_3618 ecf107cb1bd9fb357786235642f99e74 1003 Pfam PF00593 TonB dependent receptor 482 1001 1.5E-24 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_3618 ecf107cb1bd9fb357786235642f99e74 1003 Pfam PF07715 TonB-dependent Receptor Plug Domain 66 155 7.6E-10 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_1322 a02284a7d12df72fd93857e52861063e 328 Gene3D G3DSA:3.90.245.10 1 320 2.5E-97 T 13-10-2018 IPR036452 Ribonucleoside hydrolase-like Astex_1322 a02284a7d12df72fd93857e52861063e 328 SUPERFAMILY SSF53590 1 317 2.35E-87 T 13-10-2018 IPR036452 Ribonucleoside hydrolase-like Astex_1322 a02284a7d12df72fd93857e52861063e 328 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 4 310 6.0E-78 T 13-10-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain Astex_1399 23385aff20c6e83fd37ef0f597ca34bb 142 Gene3D G3DSA:3.10.450.160 63 142 1.7E-11 T 13-10-2018 Astex_1399 23385aff20c6e83fd37ef0f597ca34bb 142 Pfam PF11776 Nickel/cobalt transporter regulator 87 136 3.9E-14 T 13-10-2018 IPR024572 Nickel/cobalt homeostasis protein RcnB Astex_1399 23385aff20c6e83fd37ef0f597ca34bb 142 ProDom PD456999 SIGNAL PRECURSOR TRANSMEMBRANE MEMBRANE YOHN INTEGRAL EXPORTED SIMILAR LIPOPROTEIN LIPOPROTEIN 103 139 4.0E-8 T 13-10-2018 IPR024572 Nickel/cobalt homeostasis protein RcnB Astex_0930 c145202898a8bc290c196b74fb6052d4 289 SUPERFAMILY SSF53335 53 285 5.03E-38 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Astex_0930 c145202898a8bc290c196b74fb6052d4 289 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 5 287 27.718 T 13-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 Astex_0930 c145202898a8bc290c196b74fb6052d4 289 PIRSF PIRSF000401 16 289 7.8E-57 T 13-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 Astex_0930 c145202898a8bc290c196b74fb6052d4 289 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 41 287 1.5E-64 T 13-10-2018 Astex_0930 c145202898a8bc290c196b74fb6052d4 289 Gene3D G3DSA:3.40.50.150 95 288 2.0E-47 T 13-10-2018 Astex_1407 2d8f40d1331a37b0c2da9eadbfd6bcf5 217 TIGRFAM TIGR02451 anti_sig_ChrR: anti-sigma factor, putative, ChrR family 6 217 7.4E-49 T 13-10-2018 IPR012807 Anti-sigma factor ChrR, putative Astex_1407 2d8f40d1331a37b0c2da9eadbfd6bcf5 217 Pfam PF13490 Putative zinc-finger 15 40 1.5E-4 T 13-10-2018 IPR027383 Putative zinc-finger Astex_1407 2d8f40d1331a37b0c2da9eadbfd6bcf5 217 SUPERFAMILY SSF51182 109 212 3.96E-17 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily Astex_1407 2d8f40d1331a37b0c2da9eadbfd6bcf5 217 Gene3D G3DSA:1.10.10.1320 2 103 3.6E-26 T 13-10-2018 Astex_1407 2d8f40d1331a37b0c2da9eadbfd6bcf5 217 Pfam PF12973 ChrR Cupin-like domain 115 196 3.2E-14 T 13-10-2018 IPR025979 ChrR-like cupin domain Astex_1407 2d8f40d1331a37b0c2da9eadbfd6bcf5 217 Gene3D G3DSA:2.60.120.10 109 199 7.9E-22 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Astex_0040 edc5f16ef8fc41c316fb74a541843035 446 Gene3D G3DSA:2.20.200.10 99 335 5.6E-100 T 13-10-2018 Astex_0040 edc5f16ef8fc41c316fb74a541843035 446 Gene3D G3DSA:1.20.1600.10 53 445 5.6E-100 T 13-10-2018 Astex_0040 edc5f16ef8fc41c316fb74a541843035 446 Pfam PF02321 Outer membrane efflux protein 270 444 1.3E-19 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Astex_0040 edc5f16ef8fc41c316fb74a541843035 446 Pfam PF02321 Outer membrane efflux protein 62 238 9.0E-21 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Astex_0040 edc5f16ef8fc41c316fb74a541843035 446 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 14 445 2.5E-79 T 13-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 Astex_0040 edc5f16ef8fc41c316fb74a541843035 446 SUPERFAMILY SSF56954 7 445 5.89E-84 T 13-10-2018 Astex_2467 033545d1e267b6d7d2a819e2b0f61409 736 Pfam PF14310 Fibronectin type III-like domain 652 717 1.5E-12 T 13-10-2018 IPR026891 Fibronectin type III-like domain Astex_2467 033545d1e267b6d7d2a819e2b0f61409 736 SMART SM01217 651 718 9.3E-14 T 13-10-2018 IPR026891 Fibronectin type III-like domain Astex_2467 033545d1e267b6d7d2a819e2b0f61409 736 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 371 619 7.3E-57 T 13-10-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 Astex_2467 033545d1e267b6d7d2a819e2b0f61409 736 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 69 336 7.6E-47 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_2467 033545d1e267b6d7d2a819e2b0f61409 736 Gene3D G3DSA:3.40.50.1700 356 621 8.1E-74 T 13-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 Astex_2467 033545d1e267b6d7d2a819e2b0f61409 736 SUPERFAMILY SSF51445 34 370 8.11E-88 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_2467 033545d1e267b6d7d2a819e2b0f61409 736 SUPERFAMILY SSF52279 371 622 3.92E-52 T 13-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 Astex_2467 033545d1e267b6d7d2a819e2b0f61409 736 Gene3D G3DSA:2.60.40.10 622 735 3.8E-23 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_2467 033545d1e267b6d7d2a819e2b0f61409 736 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 268 285 - T 13-10-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 Astex_2467 033545d1e267b6d7d2a819e2b0f61409 736 PRINTS PR00133 Glycosyl hydrolase family 3 signature 91 107 2.5E-27 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_2467 033545d1e267b6d7d2a819e2b0f61409 736 PRINTS PR00133 Glycosyl hydrolase family 3 signature 198 214 2.5E-27 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_2467 033545d1e267b6d7d2a819e2b0f61409 736 PRINTS PR00133 Glycosyl hydrolase family 3 signature 268 286 2.5E-27 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_2467 033545d1e267b6d7d2a819e2b0f61409 736 PRINTS PR00133 Glycosyl hydrolase family 3 signature 121 140 2.5E-27 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_2467 033545d1e267b6d7d2a819e2b0f61409 736 PRINTS PR00133 Glycosyl hydrolase family 3 signature 167 183 2.5E-27 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_2467 033545d1e267b6d7d2a819e2b0f61409 736 Gene3D G3DSA:3.20.20.300 23 344 1.0E-95 T 13-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 Astex_1301 b29fb874486e00d82a6c99fde6436d88 782 Gene3D G3DSA:2.40.170.20 47 782 1.9E-129 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_1301 b29fb874486e00d82a6c99fde6436d88 782 Pfam PF00593 TonB dependent receptor 285 779 4.2E-42 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_1301 b29fb874486e00d82a6c99fde6436d88 782 Pfam PF07715 TonB-dependent Receptor Plug Domain 55 162 1.3E-11 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_1301 b29fb874486e00d82a6c99fde6436d88 782 SUPERFAMILY SSF56935 40 782 6.0E-100 T 13-10-2018 Astex_2950 c3da02b84dc46f43b8a54f237b9f9f79 288 Gene3D G3DSA:3.40.50.720 1 158 5.0E-41 T 13-10-2018 Astex_2950 c3da02b84dc46f43b8a54f237b9f9f79 288 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 156 9.8E-39 T 13-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 Astex_2950 c3da02b84dc46f43b8a54f237b9f9f79 288 SUPERFAMILY SSF51735 1 159 1.48E-40 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_2950 c3da02b84dc46f43b8a54f237b9f9f79 288 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 162 278 8.2E-33 T 13-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 Astex_2950 c3da02b84dc46f43b8a54f237b9f9f79 288 PIRSF PIRSF000103 1 288 9.5E-61 T 13-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 Astex_2950 c3da02b84dc46f43b8a54f237b9f9f79 288 Gene3D G3DSA:1.10.1040.10 159 287 4.8E-37 T 13-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 Astex_2950 c3da02b84dc46f43b8a54f237b9f9f79 288 SUPERFAMILY SSF48179 160 285 1.01E-38 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Astex_1118 7c1f3dd4c1ccf314785a7410f1adfecf 1154 SUPERFAMILY SSF57997 640 735 6.87E-5 T 13-10-2018 Astex_1118 7c1f3dd4c1ccf314785a7410f1adfecf 1154 Gene3D G3DSA:3.40.50.300 3 281 2.6E-43 T 13-10-2018 Astex_1118 7c1f3dd4c1ccf314785a7410f1adfecf 1154 Gene3D G3DSA:3.40.50.300 915 1154 9.6E-43 T 13-10-2018 Astex_1118 7c1f3dd4c1ccf314785a7410f1adfecf 1154 PIRSF PIRSF005719 1 1153 1.5E-197 T 13-10-2018 IPR024704 Structural maintenance of chromosomes protein Astex_1118 7c1f3dd4c1ccf314785a7410f1adfecf 1154 SUPERFAMILY SSF52540 2 1139 8.4E-52 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1118 7c1f3dd4c1ccf314785a7410f1adfecf 1154 Pfam PF02463 RecF/RecN/SMC N terminal domain 4 1139 1.4E-55 T 13-10-2018 IPR003395 RecF/RecN/SMC, N-terminal Astex_1118 7c1f3dd4c1ccf314785a7410f1adfecf 1154 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1146 3.1E-258 T 13-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 Astex_1118 7c1f3dd4c1ccf314785a7410f1adfecf 1154 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1148 20.156 T 13-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 Astex_0475 dcb050a29642f2ed8f0da1f1fdc85879 194 Pfam PF16242 Pyridoxamine 5'-phosphate oxidase like 8 160 7.0E-44 T 13-10-2018 IPR038725 General stress protein, FMN-binding split barrel domain Astex_0475 dcb050a29642f2ed8f0da1f1fdc85879 194 SUPERFAMILY SSF50475 10 140 2.06E-33 T 13-10-2018 Astex_0475 dcb050a29642f2ed8f0da1f1fdc85879 194 Gene3D G3DSA:2.30.110.10 6 168 3.2E-51 T 13-10-2018 IPR012349 FMN-binding split barrel GO:0048037 Astex_1136 50a252ce2ae848ae164c89a17078af54 168 Pfam PF06938 Protein of unknown function (DUF1285) 32 148 4.5E-30 T 13-10-2018 IPR010707 Protein of unknown function DUF1285 Astex_1136 50a252ce2ae848ae164c89a17078af54 168 Gene3D G3DSA:3.10.540.10 4 81 1.5E-29 T 13-10-2018 Astex_0418 010b8b7250fe0f282121ad2b038c4f36 326 Pfam PF00482 Type II secretion system (T2SS), protein F 184 312 2.8E-19 T 13-10-2018 IPR018076 Type II secretion system F domain Astex_3748 29f70dd8355942375b41a78ea4f3d63d 871 Gene3D G3DSA:1.10.8.80 391 508 7.2E-93 T 13-10-2018 Astex_3748 29f70dd8355942375b41a78ea4f3d63d 871 SUPERFAMILY SSF52540 317 709 1.44E-55 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_3748 29f70dd8355942375b41a78ea4f3d63d 871 Pfam PF10412 Type IV secretion-system coupling protein DNA-binding domain 317 695 4.6E-98 T 13-10-2018 IPR019476 Type IV secretion system coupling protein TraD, DNA-binding domain Astex_3748 29f70dd8355942375b41a78ea4f3d63d 871 Gene3D G3DSA:3.40.50.300 313 695 7.2E-93 T 13-10-2018 Astex_3799 e511d082e44e1ebd52d4a44a8bc9dcba 980 Pfam PF07916 TraG-like protein, N-terminal region 6 458 8.4E-104 T 13-10-2018 IPR012931 TraG-like, N-terminal Astex_3303 b1f0c2db3fc63410052101cbfc786307 638 Pfam PF01112 Asparaginase 335 627 8.7E-108 T 13-10-2018 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 Astex_3303 b1f0c2db3fc63410052101cbfc786307 638 Gene3D G3DSA:3.40.50.880 49 315 9.1E-56 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Astex_3303 b1f0c2db3fc63410052101cbfc786307 638 SUPERFAMILY SSF52317 105 274 1.83E-17 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Astex_3303 b1f0c2db3fc63410052101cbfc786307 638 Pfam PF03575 Peptidase family S51 110 262 2.1E-12 T 13-10-2018 IPR005320 Peptidase S51 GO:0006508|GO:0008236 Astex_3303 b1f0c2db3fc63410052101cbfc786307 638 SUPERFAMILY SSF56235 334 630 7.46E-91 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Astex_3303 b1f0c2db3fc63410052101cbfc786307 638 Gene3D G3DSA:3.60.20.30 503 638 4.9E-42 T 13-10-2018 Astex_2421 b86c9774979dc19ee608fcc6714a38ce 293 Pfam PF13650 Aspartyl protease 54 139 1.8E-7 T 13-10-2018 Astex_2421 b86c9774979dc19ee608fcc6714a38ce 293 Gene3D G3DSA:2.40.70.10 43 159 1.4E-7 T 13-10-2018 IPR021109 Aspartic peptidase domain superfamily Astex_2421 b86c9774979dc19ee608fcc6714a38ce 293 Gene3D G3DSA:2.40.70.10 172 290 2.5E-6 T 13-10-2018 IPR021109 Aspartic peptidase domain superfamily Astex_3241 1f6ba20233529d75c68ed1af608bff97 202 SUPERFAMILY SSF48498 88 199 6.52E-12 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily Astex_3241 1f6ba20233529d75c68ed1af608bff97 202 Pfam PF13305 WHG domain 96 178 2.2E-11 T 13-10-2018 IPR025996 WHG domain Astex_3241 1f6ba20233529d75c68ed1af608bff97 202 Gene3D G3DSA:1.10.357.10 6 198 2.5E-42 T 13-10-2018 Astex_3241 1f6ba20233529d75c68ed1af608bff97 202 SUPERFAMILY SSF46689 10 79 8.72E-9 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Astex_2978 0d979725894145f402a49564a5ab447f 310 Gene3D G3DSA:2.60.40.1180 18 81 5.9E-106 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta Astex_2978 0d979725894145f402a49564a5ab447f 310 Gene3D G3DSA:3.40.50.150 82 305 5.9E-106 T 13-10-2018 Astex_2978 0d979725894145f402a49564a5ab447f 310 SUPERFAMILY SSF53335 10 270 1.89E-54 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Astex_2978 0d979725894145f402a49564a5ab447f 310 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 122 234 3.1E-10 T 13-10-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 Astex_1773 5ead479803560437ce9fdaaf6b5b38bd 392 SUPERFAMILY SSF53383 9 380 1.88E-68 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Astex_1773 5ead479803560437ce9fdaaf6b5b38bd 392 TIGRFAM TIGR01365 serC_2: phosphoserine aminotransferase 9 382 2.8E-155 T 13-10-2018 IPR006271 Phosphoserine aminotransferase, Methanosarcina-type GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52 Astex_1773 5ead479803560437ce9fdaaf6b5b38bd 392 PIRSF PIRSF000525 1 383 1.3E-49 T 13-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 Astex_1773 5ead479803560437ce9fdaaf6b5b38bd 392 Pfam PF00266 Aminotransferase class-V 53 372 2.0E-10 T 13-10-2018 IPR000192 Aminotransferase class V domain Astex_1773 5ead479803560437ce9fdaaf6b5b38bd 392 Gene3D G3DSA:3.90.1150.10 268 382 4.5E-16 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Astex_1773 5ead479803560437ce9fdaaf6b5b38bd 392 Gene3D G3DSA:3.40.640.10 33 265 1.3E-38 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Astex_1326 b051ef3b6f203b254ad4a7f8735f327e 439 SUPERFAMILY SSF53187 28 437 1.82E-67 T 13-10-2018 Astex_1326 b051ef3b6f203b254ad4a7f8735f327e 439 Pfam PF07687 Peptidase dimerisation domain 218 307 5.4E-10 T 13-10-2018 IPR011650 Peptidase M20, dimerisation domain Astex_1326 b051ef3b6f203b254ad4a7f8735f327e 439 Pfam PF01546 Peptidase family M20/M25/M40 94 389 7.7E-22 T 13-10-2018 IPR002933 Peptidase M20 GO:0016787 Astex_1326 b051ef3b6f203b254ad4a7f8735f327e 439 PIRSF PIRSF005962 27 439 1.0E-92 T 13-10-2018 IPR017439 Amidohydrolase GO:0016787 Astex_1326 b051ef3b6f203b254ad4a7f8735f327e 439 Gene3D G3DSA:3.30.70.360 214 332 1.5E-107 T 13-10-2018 Astex_1326 b051ef3b6f203b254ad4a7f8735f327e 439 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 42 391 7.3E-78 T 13-10-2018 IPR017439 Amidohydrolase GO:0016787 Astex_1326 b051ef3b6f203b254ad4a7f8735f327e 439 SUPERFAMILY SSF55031 217 312 5.89E-24 T 13-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain Astex_1326 b051ef3b6f203b254ad4a7f8735f327e 439 Gene3D G3DSA:3.40.630.10 42 419 1.5E-107 T 13-10-2018 Astex_3524 fd1ecc28da2893ab406adcdd294b7e8b 277 Pfam PF12833 Helix-turn-helix domain 183 262 4.6E-13 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Astex_3524 fd1ecc28da2893ab406adcdd294b7e8b 277 Gene3D G3DSA:1.10.10.60 159 263 1.7E-14 T 13-10-2018 Astex_3524 fd1ecc28da2893ab406adcdd294b7e8b 277 SMART SM00342 177 261 0.0011 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 Astex_3814 9fbdd4ecddb3fb105861c84038303b19 283 SUPERFAMILY SSF56112 29 267 1.37E-42 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily Astex_3814 9fbdd4ecddb3fb105861c84038303b19 283 SMART SM00220 32 281 8.4E-16 T 13-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Astex_3814 9fbdd4ecddb3fb105861c84038303b19 283 Gene3D G3DSA:3.30.200.20 9 98 8.8E-14 T 13-10-2018 Astex_3814 9fbdd4ecddb3fb105861c84038303b19 283 Pfam PF00069 Protein kinase domain 35 237 4.2E-29 T 13-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 Astex_3814 9fbdd4ecddb3fb105861c84038303b19 283 Gene3D G3DSA:1.10.510.10 116 279 1.0E-23 T 13-10-2018 Astex_3021 69f99575bbd89181f322022bcf21aaa9 342 SUPERFAMILY SSF56042 180 341 1.0E-53 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Astex_3021 69f99575bbd89181f322022bcf21aaa9 342 Pfam PF00586 AIR synthase related protein, N-terminal domain 60 165 7.1E-16 T 13-10-2018 IPR016188 PurM-like, N-terminal domain Astex_3021 69f99575bbd89181f322022bcf21aaa9 342 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 9 340 1.7E-130 T 13-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Astex_3021 69f99575bbd89181f322022bcf21aaa9 342 Gene3D G3DSA:3.90.650.10 174 342 4.5E-65 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily Astex_3021 69f99575bbd89181f322022bcf21aaa9 342 Pfam PF02769 AIR synthase related protein, C-terminal domain 181 341 1.0E-33 T 13-10-2018 IPR010918 PurM-like, C-terminal domain Astex_3021 69f99575bbd89181f322022bcf21aaa9 342 SUPERFAMILY SSF55326 9 172 1.94E-50 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Astex_3021 69f99575bbd89181f322022bcf21aaa9 342 Gene3D G3DSA:3.30.1330.10 8 173 1.9E-68 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily Astex_3021 69f99575bbd89181f322022bcf21aaa9 342 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 9 340 42.124 T 13-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 Astex_2902 19e04f11256e898f149ff3fb115d5fed 481 SUPERFAMILY SSF103473 38 445 8.24E-35 T 13-10-2018 IPR036259 MFS transporter superfamily Astex_2902 19e04f11256e898f149ff3fb115d5fed 481 Gene3D G3DSA:1.20.1250.20 39 240 2.8E-11 T 13-10-2018 Astex_2902 19e04f11256e898f149ff3fb115d5fed 481 Gene3D G3DSA:1.20.1250.20 258 456 4.1E-16 T 13-10-2018 Astex_2902 19e04f11256e898f149ff3fb115d5fed 481 Pfam PF13347 MFS/sugar transport protein 49 455 4.7E-68 T 13-10-2018 Astex_2740 b408c349d13d287493f8a63bcfe9ae99 741 SUPERFAMILY SSF53474 490 740 9.36E-69 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_2740 b408c349d13d287493f8a63bcfe9ae99 741 Pfam PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region 132 453 6.7E-89 T 13-10-2018 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 Astex_2740 b408c349d13d287493f8a63bcfe9ae99 741 Pfam PF00326 Prolyl oligopeptidase family 544 740 2.2E-50 T 13-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 Astex_2740 b408c349d13d287493f8a63bcfe9ae99 741 Gene3D G3DSA:2.140.10.30 28 484 5.6E-150 T 13-10-2018 IPR038554 Dipeptidylpeptidase IV, N-terminal domain superfamily Astex_2740 b408c349d13d287493f8a63bcfe9ae99 741 SUPERFAMILY SSF82171 28 473 7.19E-62 T 13-10-2018 Astex_2740 b408c349d13d287493f8a63bcfe9ae99 741 Gene3D G3DSA:3.40.50.1820 494 740 1.2E-73 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_0164 6afd2000682e25f0034b6c66b6b9ffca 136 Pfam PF01475 Ferric uptake regulator family 10 129 3.3E-40 T 13-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 Astex_0164 6afd2000682e25f0034b6c66b6b9ffca 136 SUPERFAMILY SSF46785 3 131 6.35E-39 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_0164 6afd2000682e25f0034b6c66b6b9ffca 136 Gene3D G3DSA:1.10.10.10 1 83 4.5E-33 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_0164 6afd2000682e25f0034b6c66b6b9ffca 136 Gene3D G3DSA:3.30.1490.190 84 134 2.6E-17 T 13-10-2018 Astex_1358 cc80b2a965040436a7942ad3db837424 305 Pfam PF02517 CAAX protease self-immunity 139 233 2.5E-12 T 13-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 Astex_3358 f1e44544f92886357d9a969fc05fd18c 378 Gene3D G3DSA:3.40.630.10 116 374 9.6E-60 T 13-10-2018 Astex_3358 f1e44544f92886357d9a969fc05fd18c 378 Gene3D G3DSA:2.60.40.3120 2 114 2.6E-35 T 13-10-2018 Astex_3358 f1e44544f92886357d9a969fc05fd18c 378 SUPERFAMILY SSF53187 103 367 1.92E-48 T 13-10-2018 Astex_3358 f1e44544f92886357d9a969fc05fd18c 378 Pfam PF00246 Zinc carboxypeptidase 130 338 2.6E-13 T 13-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 Astex_0871 329d54a7eaed39c0d57329bc32626799 696 Gene3D G3DSA:2.40.170.20 178 696 5.6E-100 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_0871 329d54a7eaed39c0d57329bc32626799 696 Pfam PF00593 TonB dependent receptor 258 692 1.2E-50 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_0871 329d54a7eaed39c0d57329bc32626799 696 TIGRFAM TIGR01785 TonB-hemin: TonB-dependent heme/hemoglobin receptor family protein 44 696 9.2E-118 T 13-10-2018 IPR011276 TonB-dependent haem/haemoglobin receptor GO:0015232|GO:0015886|GO:0019867 Astex_0871 329d54a7eaed39c0d57329bc32626799 696 SUPERFAMILY SSF56935 37 696 1.65E-100 T 13-10-2018 Astex_0871 329d54a7eaed39c0d57329bc32626799 696 Gene3D G3DSA:2.170.130.10 54 177 4.5E-31 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_0871 329d54a7eaed39c0d57329bc32626799 696 Pfam PF07715 TonB-dependent Receptor Plug Domain 58 167 5.8E-21 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_0097 07d90492d97096ea6172aee3ad1c2eb7 383 SUPERFAMILY SSF55729 147 310 6.36E-16 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Astex_0097 07d90492d97096ea6172aee3ad1c2eb7 383 Pfam PF13480 Acetyltransferase (GNAT) domain 152 296 2.3E-30 T 13-10-2018 IPR038740 BioF2-like, acetyltransferase domain KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 Astex_0511 3c9762cca534b549293743ac9c35cfcc 335 Gene3D G3DSA:2.70.40.10 169 311 1.5E-50 T 13-10-2018 IPR036157 dUTPase-like superfamily Astex_0511 3c9762cca534b549293743ac9c35cfcc 335 SUPERFAMILY SSF51283 5 161 2.49E-21 T 13-10-2018 IPR036157 dUTPase-like superfamily Astex_0511 3c9762cca534b549293743ac9c35cfcc 335 SUPERFAMILY SSF51283 172 308 9.95E-21 T 13-10-2018 IPR036157 dUTPase-like superfamily Astex_0511 3c9762cca534b549293743ac9c35cfcc 335 Pfam PF06559 2'-deoxycytidine 5'-triphosphate deaminase (DCD) 4 166 2.5E-68 T 13-10-2018 IPR010550 Deoxycytidine triphosphate deaminase, bacterial GO:0008829|GO:0009394 Astex_0511 3c9762cca534b549293743ac9c35cfcc 335 Pfam PF06559 2'-deoxycytidine 5'-triphosphate deaminase (DCD) 176 333 1.5E-74 T 13-10-2018 IPR010550 Deoxycytidine triphosphate deaminase, bacterial GO:0008829|GO:0009394 Astex_0511 3c9762cca534b549293743ac9c35cfcc 335 Gene3D G3DSA:2.70.40.10 1 165 6.5E-45 T 13-10-2018 IPR036157 dUTPase-like superfamily Astex_0257 df0f70e24becc5dd9969b6ca015fd571 731 Pfam PF00270 DEAD/DEAH box helicase 219 366 5.0E-12 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Astex_0257 df0f70e24becc5dd9969b6ca015fd571 731 TIGRFAM TIGR00595 priA: primosomal protein N' 221 728 4.4E-169 T 13-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 Astex_0257 df0f70e24becc5dd9969b6ca015fd571 731 SMART SM00490 497 594 4.3E-7 T 13-10-2018 IPR001650 Helicase, C-terminal Astex_0257 df0f70e24becc5dd9969b6ca015fd571 731 Hamap MF_00983 Probable primosomal protein N' [priA]. 21 730 21.087 T 13-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 Astex_0257 df0f70e24becc5dd9969b6ca015fd571 731 SMART SM00487 193 394 1.0E-17 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Astex_0257 df0f70e24becc5dd9969b6ca015fd571 731 SUPERFAMILY SSF52540 214 605 4.05E-36 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0257 df0f70e24becc5dd9969b6ca015fd571 731 Pfam PF00271 Helicase conserved C-terminal domain 506 593 4.6E-6 T 13-10-2018 IPR001650 Helicase, C-terminal Astex_0257 df0f70e24becc5dd9969b6ca015fd571 731 Gene3D G3DSA:3.40.50.300 189 381 1.5E-62 T 13-10-2018 Astex_0257 df0f70e24becc5dd9969b6ca015fd571 731 Gene3D G3DSA:1.10.8.630 18 121 1.2E-15 T 13-10-2018 Astex_0596 4fc142d3f655d91cb4618ede187727f5 110 Gene3D G3DSA:2.30.330.10 21 109 8.6E-31 T 13-10-2018 IPR036429 SpoA-like superfamily Astex_0596 4fc142d3f655d91cb4618ede187727f5 110 SUPERFAMILY SSF101801 31 107 2.49E-23 T 13-10-2018 IPR036429 SpoA-like superfamily Astex_0596 4fc142d3f655d91cb4618ede187727f5 110 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 34 105 6.3E-30 T 13-10-2018 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 Astex_0596 4fc142d3f655d91cb4618ede187727f5 110 PRINTS PR00956 Flagellar motor switch protein FliN signature 33 49 1.9E-25 T 13-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 Astex_0596 4fc142d3f655d91cb4618ede187727f5 110 PRINTS PR00956 Flagellar motor switch protein FliN signature 66 79 1.9E-25 T 13-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 Astex_0596 4fc142d3f655d91cb4618ede187727f5 110 PRINTS PR00956 Flagellar motor switch protein FliN signature 50 66 1.9E-25 T 13-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 Astex_0596 4fc142d3f655d91cb4618ede187727f5 110 PRINTS PR00956 Flagellar motor switch protein FliN signature 79 94 1.9E-25 T 13-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 Astex_0596 4fc142d3f655d91cb4618ede187727f5 110 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 34 103 4.0E-25 T 13-10-2018 IPR001543 Surface presentation of antigen (SpoA) Astex_3333 a01ecc2210ff24c98682a1da0b3072d5 223 Gene3D G3DSA:1.10.3720.10 14 223 1.3E-46 T 13-10-2018 IPR035906 MetI-like superfamily Astex_3333 a01ecc2210ff24c98682a1da0b3072d5 223 SUPERFAMILY SSF161098 16 207 4.06E-43 T 13-10-2018 IPR035906 MetI-like superfamily Astex_3333 a01ecc2210ff24c98682a1da0b3072d5 223 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 37 218 2.1E-20 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Astex_3328 f6c101f2d69f2407cce87c884dd0ca69 82 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 3 64 6.8E-10 T 13-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM Astex_3328 f6c101f2d69f2407cce87c884dd0ca69 82 SUPERFAMILY SSF143120 2 77 3.53E-11 T 13-10-2018 IPR036165 YefM-like superfamily Astex_1149 ffcfd6ee6d57430513460cc7bb273330 202 Gene3D G3DSA:3.40.50.1470 1 192 9.6E-61 T 13-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 Astex_1149 ffcfd6ee6d57430513460cc7bb273330 202 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 1 180 31.847 T 13-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 Astex_1149 ffcfd6ee6d57430513460cc7bb273330 202 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 111 121 - T 13-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 Astex_1149 ffcfd6ee6d57430513460cc7bb273330 202 Pfam PF01195 Peptidyl-tRNA hydrolase 3 184 1.8E-51 T 13-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 Astex_1149 ffcfd6ee6d57430513460cc7bb273330 202 SUPERFAMILY SSF53178 2 185 6.15E-60 T 13-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 Astex_1149 ffcfd6ee6d57430513460cc7bb273330 202 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 14 27 - T 13-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 Astex_1149 ffcfd6ee6d57430513460cc7bb273330 202 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 3 174 8.4E-51 T 13-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 Astex_3430 3d3a1e03cc876cc31da9204252621fdf 296 SUPERFAMILY SSF53474 22 290 1.79E-44 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_3430 3d3a1e03cc876cc31da9204252621fdf 296 Gene3D G3DSA:3.40.50.1820 20 291 1.6E-68 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_3430 3d3a1e03cc876cc31da9204252621fdf 296 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 4.7E-7 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Astex_3430 3d3a1e03cc876cc31da9204252621fdf 296 PRINTS PR00111 Alpha/beta hydrolase fold signature 122 135 4.7E-7 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Astex_3430 3d3a1e03cc876cc31da9204252621fdf 296 PRINTS PR00111 Alpha/beta hydrolase fold signature 62 77 4.7E-7 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Astex_3430 3d3a1e03cc876cc31da9204252621fdf 296 Pfam PF00561 alpha/beta hydrolase fold 38 137 1.6E-21 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Astex_2854 ee7fb78ba138fd50be4d5d5e69f978e6 165 Gene3D G3DSA:3.10.129.10 17 165 1.7E-58 T 13-10-2018 Astex_2854 ee7fb78ba138fd50be4d5d5e69f978e6 165 SUPERFAMILY SSF54637 21 160 3.1E-49 T 13-10-2018 IPR029069 HotDog domain superfamily Astex_2854 ee7fb78ba138fd50be4d5d5e69f978e6 165 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 21 162 33.442 T 13-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 Astex_2854 ee7fb78ba138fd50be4d5d5e69f978e6 165 Pfam PF07977 FabA-like domain 30 154 2.0E-33 T 13-10-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 Astex_2854 ee7fb78ba138fd50be4d5d5e69f978e6 165 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 23 159 1.3E-54 T 13-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 Astex_2112 573108270f064a56b855e2f543176f87 605 SUPERFAMILY SSF52540 75 361 4.04E-75 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2112 573108270f064a56b855e2f543176f87 605 SMART SM00490 259 340 1.8E-33 T 13-10-2018 IPR001650 Helicase, C-terminal Astex_2112 573108270f064a56b855e2f543176f87 605 Pfam PF00271 Helicase conserved C-terminal domain 235 340 7.0E-28 T 13-10-2018 IPR001650 Helicase, C-terminal Astex_2112 573108270f064a56b855e2f543176f87 605 Gene3D G3DSA:3.40.50.300 1 211 1.6E-77 T 13-10-2018 Astex_2112 573108270f064a56b855e2f543176f87 605 SMART SM00487 21 223 1.2E-60 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Astex_2112 573108270f064a56b855e2f543176f87 605 Gene3D G3DSA:3.40.50.300 214 426 8.9E-52 T 13-10-2018 Astex_2112 573108270f064a56b855e2f543176f87 605 Pfam PF00270 DEAD/DEAH box helicase 26 194 4.3E-49 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 Astex_2497 71d60b60df97a14459ccde56576ed04c 511 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 42 312 9.8E-48 T 13-10-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 Astex_2497 71d60b60df97a14459ccde56576ed04c 511 Gene3D G3DSA:2.60.120.260 356 500 1.3E-8 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_2497 71d60b60df97a14459ccde56576ed04c 511 SUPERFAMILY SSF49785 387 491 4.53E-6 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_2497 71d60b60df97a14459ccde56576ed04c 511 SUPERFAMILY SSF51445 13 334 1.3E-62 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_2497 71d60b60df97a14459ccde56576ed04c 511 Gene3D G3DSA:3.20.20.80 29 339 2.2E-77 T 13-10-2018 Astex_2497 71d60b60df97a14459ccde56576ed04c 511 ProSitePatterns PS00659 Glycosyl hydrolases family 5 signature. 152 161 - T 13-10-2018 IPR018087 Glycoside hydrolase, family 5, conserved site GO:0004553|GO:0005975 Astex_1268 b757a1d58a5e53c22ae72cc1025f4c12 269 Pfam PF01975 Survival protein SurE 3 186 1.2E-52 T 13-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 Astex_1268 b757a1d58a5e53c22ae72cc1025f4c12 269 SUPERFAMILY SSF64167 1 253 8.11E-76 T 13-10-2018 Astex_1268 b757a1d58a5e53c22ae72cc1025f4c12 269 Gene3D G3DSA:3.40.1210.10 1 258 1.2E-84 T 13-10-2018 IPR036523 SurE-like phosphatase/nucleotidase superfamily GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 Astex_1268 b757a1d58a5e53c22ae72cc1025f4c12 269 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 1 256 35.822 T 13-10-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 Astex_1268 b757a1d58a5e53c22ae72cc1025f4c12 269 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 1 239 3.9E-62 T 13-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 Astex_2106 3df3358a54c123a7a528c0dbc7ace197 300 SUPERFAMILY SSF118352 252 298 1.7E-11 T 13-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 Astex_2106 3df3358a54c123a7a528c0dbc7ace197 300 PIRSF PIRSF005261 4 299 1.3E-75 T 13-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 Astex_2106 3df3358a54c123a7a528c0dbc7ace197 300 SUPERFAMILY SSF64397 10 258 1.83E-58 T 13-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 Astex_2106 3df3358a54c123a7a528c0dbc7ace197 300 Gene3D G3DSA:3.55.30.10 5 196 1.1E-55 T 13-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 Astex_2106 3df3358a54c123a7a528c0dbc7ace197 300 Gene3D G3DSA:1.10.287.480 202 252 8.5E-11 T 13-10-2018 IPR023212 Heat shock protein Hsp33, helix hairpin bin domain superfamily Astex_2106 3df3358a54c123a7a528c0dbc7ace197 300 Gene3D G3DSA:3.90.1280.10 253 299 3.9E-10 T 13-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 Astex_2106 3df3358a54c123a7a528c0dbc7ace197 300 Pfam PF01430 Hsp33 protein 10 296 1.5E-73 T 13-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 Astex_1646 4cfd33b02260acdc49ed09ff876e81cd 334 SUPERFAMILY SSF53335 154 313 2.13E-23 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Astex_1646 4cfd33b02260acdc49ed09ff876e81cd 334 Gene3D G3DSA:3.40.50.150 154 334 1.4E-38 T 13-10-2018 Astex_1646 4cfd33b02260acdc49ed09ff876e81cd 334 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 263 269 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 Astex_1646 4cfd33b02260acdc49ed09ff876e81cd 334 Pfam PF05175 Methyltransferase small domain 167 331 7.3E-49 T 13-10-2018 IPR007848 Methyltransferase small domain GO:0008168 Astex_3069 cfb41a2763c53893846134560122701a 223 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 203 4.6E-36 T 13-10-2018 Astex_3069 cfb41a2763c53893846134560122701a 223 SUPERFAMILY SSF52317 1 218 1.58E-67 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Astex_3069 cfb41a2763c53893846134560122701a 223 PIRSF PIRSF001586 1 223 1.5E-80 T 13-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 Astex_3069 cfb41a2763c53893846134560122701a 223 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 1 218 3.9E-84 T 13-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 Astex_3069 cfb41a2763c53893846134560122701a 223 Gene3D G3DSA:3.40.50.880 1 222 5.4E-62 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like Astex_3069 cfb41a2763c53893846134560122701a 223 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 1 218 40.982 T 13-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 Astex_3069 cfb41a2763c53893846134560122701a 223 SMART SM01211 1 220 9.2E-114 T 13-10-2018 Astex_2916 26952a0291701403cad224569e265ce8 443 Pfam PF03929 PepSY-associated TM region 20 379 2.6E-65 T 13-10-2018 IPR005625 PepSY-associated TM protein Astex_2458 1cc557156de98804cb8770a124c74c66 662 Pfam PF11843 Protein of unknown function (DUF3363) 276 659 5.6E-136 T 13-10-2018 IPR021795 Protein of unknown function DUF3363 Astex_1336 3a703cf27ff2c420c6b8cf5014d7e6b7 184 SUPERFAMILY SSF53955 43 172 1.78E-45 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily Astex_1336 3a703cf27ff2c420c6b8cf5014d7e6b7 184 Gene3D G3DSA:1.10.530.10 41 175 2.5E-43 T 13-10-2018 Astex_1336 3a703cf27ff2c420c6b8cf5014d7e6b7 184 Pfam PF01464 Transglycosylase SLT domain 56 154 5.1E-28 T 13-10-2018 IPR008258 Transglycosylase SLT domain 1 Astex_1336 3a703cf27ff2c420c6b8cf5014d7e6b7 184 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 74 102 - T 13-10-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 Astex_0790 72ed1890af9f74d4dbf053c20a7ba886 844 Pfam PF07715 TonB-dependent Receptor Plug Domain 54 159 5.0E-14 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_0790 72ed1890af9f74d4dbf053c20a7ba886 844 Gene3D G3DSA:2.40.170.20 550 844 2.4E-47 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_0790 72ed1890af9f74d4dbf053c20a7ba886 844 Gene3D G3DSA:2.40.170.20 45 522 8.0E-70 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_0790 72ed1890af9f74d4dbf053c20a7ba886 844 SUPERFAMILY SSF56935 36 844 5.1E-107 T 13-10-2018 Astex_0790 72ed1890af9f74d4dbf053c20a7ba886 844 Pfam PF00593 TonB dependent receptor 364 843 3.8E-35 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_3016 b973c5da3ad4b41c4bbd21675986798f 221 Pfam PF00308 Bacterial dnaA protein 93 192 8.6E-6 T 13-10-2018 IPR013317 Chromosomal replication initiator protein DnaA Astex_3016 b973c5da3ad4b41c4bbd21675986798f 221 SUPERFAMILY SSF52540 13 185 4.62E-15 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_3016 b973c5da3ad4b41c4bbd21675986798f 221 Gene3D G3DSA:3.40.50.300 1 76 2.4E-8 T 13-10-2018 Astex_0403 058a5280bdb097de3a373b5d4e9a15ed 172 SUPERFAMILY SSF141091 1 101 4.71E-33 T 13-10-2018 IPR036164 L21-like superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0403 058a5280bdb097de3a373b5d4e9a15ed 172 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 100 5.1E-36 T 13-10-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0403 058a5280bdb097de3a373b5d4e9a15ed 172 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 24.88 T 13-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0403 058a5280bdb097de3a373b5d4e9a15ed 172 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 2.6E-29 T 13-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_1821 2bc6adecac7f16a40980999444bcda0d 118 Gene3D G3DSA:3.30.2310.20 1 98 3.1E-18 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Astex_1821 2bc6adecac7f16a40980999444bcda0d 118 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 3 93 2.5E-13 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family Astex_0213 909707c376a3a84f0cf6a02455bc5272 377 Pfam PF04982 HPP family 55 171 7.2E-37 T 13-10-2018 IPR007065 HPP Astex_0213 909707c376a3a84f0cf6a02455bc5272 377 Pfam PF00571 CBS domain 232 284 2.1E-7 T 13-10-2018 IPR000644 CBS domain Astex_0213 909707c376a3a84f0cf6a02455bc5272 377 Pfam PF00571 CBS domain 315 370 2.8E-8 T 13-10-2018 IPR000644 CBS domain Astex_0213 909707c376a3a84f0cf6a02455bc5272 377 Gene3D G3DSA:3.10.580.10 215 375 1.1E-27 T 13-10-2018 Astex_0213 909707c376a3a84f0cf6a02455bc5272 377 SUPERFAMILY SSF54631 227 374 1.53E-26 T 13-10-2018 Astex_0213 909707c376a3a84f0cf6a02455bc5272 377 SMART SM00116 322 370 2.2E-4 T 13-10-2018 IPR000644 CBS domain Astex_0213 909707c376a3a84f0cf6a02455bc5272 377 SMART SM00116 239 287 0.0026 T 13-10-2018 IPR000644 CBS domain Astex_3680 df7e696b9c3fbb8077ad28ab99da682a 400 SUPERFAMILY SSF56059 6 397 1.65E-64 T 13-10-2018 Astex_3680 df7e696b9c3fbb8077ad28ab99da682a 400 Gene3D G3DSA:3.30.1490.330 273 356 3.0E-20 T 13-10-2018 Astex_3680 df7e696b9c3fbb8077ad28ab99da682a 400 SUPERFAMILY SSF52440 177 289 1.15E-29 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily Astex_3680 df7e696b9c3fbb8077ad28ab99da682a 400 Pfam PF03738 Glutathionylspermidine synthase preATP-grasp 12 399 1.9E-133 T 13-10-2018 IPR005494 Glutathionylspermidine synthase, pre-ATP-grasp-like domain Astex_2969 2d083b34a89e4a533692b36be53c2928 183 Gene3D G3DSA:3.30.70.560 13 170 3.4E-43 T 13-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 Astex_2969 2d083b34a89e4a533692b36be53c2928 183 SUPERFAMILY SSF55083 15 165 1.01E-38 T 13-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 Astex_2969 2d083b34a89e4a533692b36be53c2928 183 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 16 147 2.2E-32 T 13-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 Astex_2969 2d083b34a89e4a533692b36be53c2928 183 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 16 147 1.4E-28 T 13-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 Astex_0894 6f539da67ec096ce5bcb9a58a192bdb0 384 Pfam PF01546 Peptidase family M20/M25/M40 69 377 1.3E-41 T 13-10-2018 IPR002933 Peptidase M20 GO:0016787 Astex_0894 6f539da67ec096ce5bcb9a58a192bdb0 384 Pfam PF07687 Peptidase dimerisation domain 178 284 3.9E-17 T 13-10-2018 IPR011650 Peptidase M20, dimerisation domain Astex_0894 6f539da67ec096ce5bcb9a58a192bdb0 384 SUPERFAMILY SSF55031 182 291 2.99E-23 T 13-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain Astex_0894 6f539da67ec096ce5bcb9a58a192bdb0 384 SUPERFAMILY SSF53187 10 380 1.15E-59 T 13-10-2018 Astex_0894 6f539da67ec096ce5bcb9a58a192bdb0 384 TIGRFAM TIGR01246 dapE_proteo: succinyl-diaminopimelate desuccinylase 12 377 3.8E-126 T 13-10-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 Astex_0894 6f539da67ec096ce5bcb9a58a192bdb0 384 Hamap MF_01690 Succinyl-diaminopimelate desuccinylase [dapE]. 9 381 47.35 T 13-10-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 Astex_0894 6f539da67ec096ce5bcb9a58a192bdb0 384 Gene3D G3DSA:3.30.70.360 182 299 1.7E-109 T 13-10-2018 Astex_0894 6f539da67ec096ce5bcb9a58a192bdb0 384 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 104 139 - T 13-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 Astex_0894 6f539da67ec096ce5bcb9a58a192bdb0 384 Gene3D G3DSA:3.40.630.10 14 368 1.7E-109 T 13-10-2018 Astex_2487 34dabbf5170774c9a8f3c36f5ff4995d 248 Pfam PF04335 VirB8 protein 22 225 1.4E-63 T 13-10-2018 IPR007430 Bacterial virulence protein VirB8 GO:0016020 Astex_2487 34dabbf5170774c9a8f3c36f5ff4995d 248 Gene3D G3DSA:3.10.450.230 89 232 2.8E-6 T 13-10-2018 Astex_2487 34dabbf5170774c9a8f3c36f5ff4995d 248 SUPERFAMILY SSF54427 93 227 3.81E-28 T 13-10-2018 IPR032710 NTF2-like domain superfamily Astex_0199 e527c7e5ecd8c631605170513954ec94 144 Pfam PF00886 Ribosomal protein S16 8 69 2.1E-22 T 13-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0199 e527c7e5ecd8c631605170513954ec94 144 TIGRFAM TIGR00002 S16: ribosomal protein bS16 2 81 4.8E-30 T 13-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0199 e527c7e5ecd8c631605170513954ec94 144 SUPERFAMILY SSF54565 1 89 2.49E-29 T 13-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0199 e527c7e5ecd8c631605170513954ec94 144 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 1 79 23.127 T 13-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0199 e527c7e5ecd8c631605170513954ec94 144 Gene3D G3DSA:3.30.1320.10 1 142 7.4E-34 T 13-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_2670 45693bd201534ee3877016711d8144ff 395 Pfam PF04610 TrbL/VirB6 plasmid conjugal transfer protein 37 254 3.3E-49 T 13-10-2018 IPR007688 Plasmid conjugal transfer TrbL/VirB6 GO:0030255 Astex_2670 45693bd201534ee3877016711d8144ff 395 TIGRFAM TIGR02783 TrbL_P: P-type conjugative transfer protein TrbL 3 304 1.6E-63 T 13-10-2018 IPR014150 Conjugal transfer, TrbL Astex_1835 93345fcc1acd2766fe8df8fb6f103c95 210 Pfam PF00881 Nitroreductase family 49 187 1.1E-17 T 13-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 Astex_1835 93345fcc1acd2766fe8df8fb6f103c95 210 PIRSF PIRSF000232 24 210 4.1E-45 T 13-10-2018 IPR026021 Putative NAD(P)H nitroreductase YdjA-like Astex_1835 93345fcc1acd2766fe8df8fb6f103c95 210 Gene3D G3DSA:3.40.109.10 23 209 1.1E-29 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 Astex_1835 93345fcc1acd2766fe8df8fb6f103c95 210 SUPERFAMILY SSF55469 29 207 2.36E-30 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 Astex_0012 f42b9dbd10867e0a17eaa133e11fafec 243 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 9 223 6.0E-39 T 13-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 Astex_0012 f42b9dbd10867e0a17eaa133e11fafec 243 Pfam PF01914 MarC family integral membrane protein 10 226 8.2E-41 T 13-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 Astex_0991 cde1efe11d5015fdfa9fe07b705c6aa9 60 Gene3D G3DSA:1.10.8.1250 1 58 4.5E-13 T 13-10-2018 IPR038296 Antitoxin ParD superfamily Astex_0991 cde1efe11d5015fdfa9fe07b705c6aa9 60 Pfam PF03693 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH 5 53 1.8E-7 T 13-10-2018 IPR022789 Antitoxin ParD Astex_0991 cde1efe11d5015fdfa9fe07b705c6aa9 60 SUPERFAMILY SSF47598 2 31 1.89E-5 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 Astex_0991 cde1efe11d5015fdfa9fe07b705c6aa9 60 TIGRFAM TIGR02606 antidote_CC2985: putative addiction module antidote protein, CC2985 family 1 53 6.4E-13 T 13-10-2018 IPR022789 Antitoxin ParD Astex_1730 4012378f3221e0e45640520e7a3da1d6 218 SUPERFAMILY SSF54001 28 215 5.89E-37 T 13-10-2018 IPR038765 Papain-like cysteine peptidase superfamily Astex_1730 4012378f3221e0e45640520e7a3da1d6 218 Gene3D G3DSA:3.90.1720.10 27 218 2.5E-44 T 13-10-2018 Astex_1730 4012378f3221e0e45640520e7a3da1d6 218 Pfam PF05708 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family 29 213 3.9E-32 T 13-10-2018 IPR024453 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family Astex_2628 cff055c94bfc7b68a827dd91c6030be6 157 SMART SM00422 23 90 1.6E-20 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Astex_2628 cff055c94bfc7b68a827dd91c6030be6 157 SUPERFAMILY SSF46955 23 133 2.12E-25 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily Astex_2628 cff055c94bfc7b68a827dd91c6030be6 157 Gene3D G3DSA:1.10.1660.10 21 156 7.7E-28 T 13-10-2018 Astex_2628 cff055c94bfc7b68a827dd91c6030be6 157 Pfam PF13411 MerR HTH family regulatory protein 23 88 3.9E-17 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 Astex_0473 d47e2d4d84277dc576e7cb105347dc5d 362 Gene3D G3DSA:2.30.40.20 29 79 1.5E-64 T 13-10-2018 Astex_0473 d47e2d4d84277dc576e7cb105347dc5d 362 SUPERFAMILY SSF56672 6 240 1.69E-92 T 13-10-2018 Astex_0473 d47e2d4d84277dc576e7cb105347dc5d 362 Pfam PF00817 impB/mucB/samB family 15 160 2.8E-51 T 13-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 Astex_0473 d47e2d4d84277dc576e7cb105347dc5d 362 SUPERFAMILY SSF100879 244 344 7.06E-25 T 13-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 Astex_0473 d47e2d4d84277dc576e7cb105347dc5d 362 Gene3D G3DSA:3.30.1490.100 243 362 1.9E-24 T 13-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 Astex_0473 d47e2d4d84277dc576e7cb105347dc5d 362 Pfam PF11799 impB/mucB/samB family C-terminal domain 240 353 4.8E-14 T 13-10-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 Astex_0473 d47e2d4d84277dc576e7cb105347dc5d 362 Hamap MF_01113 DNA polymerase IV [dinB]. 9 360 38.365 T 13-10-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 Astex_0473 d47e2d4d84277dc576e7cb105347dc5d 362 Gene3D G3DSA:3.30.70.270 12 170 1.5E-64 T 13-10-2018 Astex_0473 d47e2d4d84277dc576e7cb105347dc5d 362 Gene3D G3DSA:1.10.150.20 172 235 2.4E-15 T 13-10-2018 Astex_3252 3ff1c8c10384f4cb7b104c5d0a7e16cb 84 TIGRFAM TIGR02181 GRX_bact: glutaredoxin 3 4 82 3.7E-34 T 13-10-2018 IPR011900 Glutaredoxin, GrxC GO:0045454 Astex_3252 3ff1c8c10384f4cb7b104c5d0a7e16cb 84 PRINTS PR00160 Glutaredoxin signature 4 22 1.6E-16 T 13-10-2018 IPR014025 Glutaredoxin subgroup Astex_3252 3ff1c8c10384f4cb7b104c5d0a7e16cb 84 PRINTS PR00160 Glutaredoxin signature 60 73 1.6E-16 T 13-10-2018 IPR014025 Glutaredoxin subgroup Astex_3252 3ff1c8c10384f4cb7b104c5d0a7e16cb 84 PRINTS PR00160 Glutaredoxin signature 46 59 1.6E-16 T 13-10-2018 IPR014025 Glutaredoxin subgroup Astex_3252 3ff1c8c10384f4cb7b104c5d0a7e16cb 84 SUPERFAMILY SSF52833 1 83 9.27E-29 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Astex_3252 3ff1c8c10384f4cb7b104c5d0a7e16cb 84 Pfam PF00462 Glutaredoxin 4 63 3.1E-24 T 13-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 Astex_3252 3ff1c8c10384f4cb7b104c5d0a7e16cb 84 Gene3D G3DSA:3.40.30.10 2 84 1.9E-28 T 13-10-2018 Astex_3252 3ff1c8c10384f4cb7b104c5d0a7e16cb 84 ProSitePatterns PS00195 Glutaredoxin active site. 6 22 - T 13-10-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 Astex_0081 e6f013b21d0c2efa4e54d4c0a056c5a3 239 SUPERFAMILY SSF53448 2 236 1.08E-44 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_0081 e6f013b21d0c2efa4e54d4c0a056c5a3 239 Pfam PF12804 MobA-like NTP transferase domain 7 140 3.7E-16 T 13-10-2018 IPR025877 MobA-like NTP transferase Astex_0081 e6f013b21d0c2efa4e54d4c0a056c5a3 239 Gene3D G3DSA:3.90.550.10 6 238 3.1E-47 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_2199 107167e6e629bbf57e1ec4e8f50bbed3 526 Pfam PF03050 Transposase IS66 family 185 469 3.9E-104 T 13-10-2018 IPR004291 Transposase, IS66 Astex_2199 107167e6e629bbf57e1ec4e8f50bbed3 526 Pfam PF13817 IS66 C-terminal element 476 513 5.3E-13 T 13-10-2018 IPR039552 Transposase IS66, C-terminal Astex_2199 107167e6e629bbf57e1ec4e8f50bbed3 526 Pfam PF13005 zinc-finger binding domain of transposase IS66 125 170 1.5E-8 T 13-10-2018 IPR024474 Zinc-finger binding domain of transposase IS66 Astex_2199 107167e6e629bbf57e1ec4e8f50bbed3 526 Pfam PF13007 Transposase C of IS166 homeodomain 47 119 3.1E-14 T 13-10-2018 IPR024463 Transposase TnpC, homeodomain Astex_3028 1eb6f695e6e227b7bca18a2c6cf633ec 384 Pfam PF03739 Predicted permease YjgP/YjgQ family 7 357 1.4E-51 T 13-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 Astex_0293 3d70455cd910becad345b2e28aa81bb9 117 Pfam PF07237 Protein of unknown function (DUF1428) 2 103 2.9E-43 T 13-10-2018 IPR009874 Protein of unknown function DUF1428 Astex_0293 3d70455cd910becad345b2e28aa81bb9 117 SUPERFAMILY SSF54909 1 116 8.58E-45 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel Astex_0293 3d70455cd910becad345b2e28aa81bb9 117 PIRSF PIRSF007028 1 117 1.3E-45 T 13-10-2018 IPR009874 Protein of unknown function DUF1428 Astex_0293 3d70455cd910becad345b2e28aa81bb9 117 Gene3D G3DSA:3.30.70.100 1 117 3.2E-42 T 13-10-2018 Astex_2779 80debfdeb31136fc662c4fe4ad0a22e9 819 SUPERFAMILY SSF56935 46 790 6.02E-100 T 13-10-2018 Astex_2779 80debfdeb31136fc662c4fe4ad0a22e9 819 Pfam PF00593 TonB dependent receptor 290 784 4.8E-42 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_2779 80debfdeb31136fc662c4fe4ad0a22e9 819 Gene3D G3DSA:2.40.170.20 235 783 2.0E-55 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_2779 80debfdeb31136fc662c4fe4ad0a22e9 819 Gene3D G3DSA:2.170.130.10 39 183 3.0E-34 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_2779 80debfdeb31136fc662c4fe4ad0a22e9 819 Pfam PF07715 TonB-dependent Receptor Plug Domain 58 179 1.0E-20 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_2252 e7a7a6104267bfea04cce88a5a5e6721 326 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 228 322 4.0E-18 T 13-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 Astex_2252 e7a7a6104267bfea04cce88a5a5e6721 326 SMART SM00729 51 264 9.7E-39 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Astex_2252 e7a7a6104267bfea04cce88a5a5e6721 326 Hamap MF_01694 Biotin synthase [bioB]. 13 325 41.815 T 13-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 Astex_2252 e7a7a6104267bfea04cce88a5a5e6721 326 Pfam PF04055 Radical SAM superfamily 58 215 1.1E-16 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Astex_2252 e7a7a6104267bfea04cce88a5a5e6721 326 PIRSF PIRSF001619 2 326 4.9E-130 T 13-10-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 Astex_2252 e7a7a6104267bfea04cce88a5a5e6721 326 SUPERFAMILY SSF102114 13 325 1.7E-90 T 13-10-2018 Astex_2252 e7a7a6104267bfea04cce88a5a5e6721 326 TIGRFAM TIGR00433 bioB: biotin synthase 23 322 1.7E-116 T 13-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 Astex_2252 e7a7a6104267bfea04cce88a5a5e6721 326 Gene3D G3DSA:3.20.20.70 12 326 5.5E-125 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_2252 e7a7a6104267bfea04cce88a5a5e6721 326 SMART SM00876 228 324 2.9E-42 T 13-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 Astex_0573 e976df3c49337e1eb494aa409cbc37dd 233 SMART SM00862 149 224 2.1E-24 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Astex_0573 e976df3c49337e1eb494aa409cbc37dd 233 Pfam PF00072 Response regulator receiver domain 6 116 2.0E-20 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_0573 e976df3c49337e1eb494aa409cbc37dd 233 SMART SM00448 4 115 1.0E-27 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_0573 e976df3c49337e1eb494aa409cbc37dd 233 Gene3D G3DSA:3.40.50.2300 2 124 9.7E-32 T 13-10-2018 Astex_0573 e976df3c49337e1eb494aa409cbc37dd 233 Gene3D G3DSA:1.10.10.10 127 231 6.3E-30 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_0573 e976df3c49337e1eb494aa409cbc37dd 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 224 5.1E-25 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Astex_0573 e976df3c49337e1eb494aa409cbc37dd 233 SUPERFAMILY SSF52172 1 177 1.79E-30 T 13-10-2018 IPR011006 CheY-like superfamily Astex_1117 8542f02e9ead3a6497268259ffff9578 97 PIRSF PIRSF032126 1 97 3.2E-21 T 13-10-2018 IPR016989 ATP synthase protein I, alphaproteobacterial Astex_1117 8542f02e9ead3a6497268259ffff9578 97 Pfam PF09527 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter 50 93 2.8E-10 T 13-10-2018 IPR032820 Putative F0F1-ATPase subunit, Ca2+/Mg2+ transporter Astex_0884 d834512a8c7c22c5ad27fbe216b82b50 105 Pfam PF02575 YbaB/EbfC DNA-binding family 7 94 1.7E-27 T 13-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family Astex_0884 d834512a8c7c22c5ad27fbe216b82b50 105 Gene3D G3DSA:3.30.1310.10 3 105 7.8E-29 T 13-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily Astex_0884 d834512a8c7c22c5ad27fbe216b82b50 105 PIRSF PIRSF004555 1 105 6.4E-29 T 13-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family Astex_0884 d834512a8c7c22c5ad27fbe216b82b50 105 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 1 95 19.114 T 13-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family Astex_0884 d834512a8c7c22c5ad27fbe216b82b50 105 SUPERFAMILY SSF82607 3 93 1.57E-23 T 13-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily Astex_0884 d834512a8c7c22c5ad27fbe216b82b50 105 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 3 92 1.0E-21 T 13-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family Astex_2637 a64033fac096d7018329de1b0217aff1 126 TIGRFAM TIGR02097 yccV: hemimethylated DNA binding domain 23 120 5.5E-34 T 13-10-2018 IPR011722 Hemimethylated DNA-binding domain GO:0003677 Astex_2637 a64033fac096d7018329de1b0217aff1 126 Pfam PF08755 Hemimethylated DNA-binding protein YccV like 24 116 1.4E-22 T 13-10-2018 IPR011722 Hemimethylated DNA-binding domain GO:0003677 Astex_2637 a64033fac096d7018329de1b0217aff1 126 SMART SM00992 22 121 3.7E-45 T 13-10-2018 IPR011722 Hemimethylated DNA-binding domain GO:0003677 Astex_2637 a64033fac096d7018329de1b0217aff1 126 SUPERFAMILY SSF141255 23 115 2.35E-30 T 13-10-2018 IPR036623 Hemimethylated DNA-binding domain superfamily GO:0003677 Astex_2637 a64033fac096d7018329de1b0217aff1 126 Gene3D G3DSA:2.30.30.390 21 124 1.3E-26 T 13-10-2018 IPR036623 Hemimethylated DNA-binding domain superfamily GO:0003677 Astex_0291 8a37b99387de7184eebc68cb64cea915 319 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 293 318 1.0E-44 T 13-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 Astex_0291 8a37b99387de7184eebc68cb64cea915 319 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 24 51 1.0E-44 T 13-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 Astex_0291 8a37b99387de7184eebc68cb64cea915 319 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 61 87 1.0E-44 T 13-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 Astex_0291 8a37b99387de7184eebc68cb64cea915 319 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 137 160 1.0E-44 T 13-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 Astex_0291 8a37b99387de7184eebc68cb64cea915 319 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 193 220 1.0E-44 T 13-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 Astex_0291 8a37b99387de7184eebc68cb64cea915 319 Gene3D G3DSA:3.30.540.10 2 182 4.6E-53 T 13-10-2018 Astex_0291 8a37b99387de7184eebc68cb64cea915 319 Pfam PF00316 Fructose-1-6-bisphosphatase, N-terminal domain 14 181 5.0E-50 T 13-10-2018 IPR033391 Fructose-1-6-bisphosphatase class I, N-terminal KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 Astex_0291 8a37b99387de7184eebc68cb64cea915 319 Hamap MF_01855 Fructose-1,6-bisphosphatase class 1 [fbp]. 3 319 42.622 T 13-10-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 Astex_0291 8a37b99387de7184eebc68cb64cea915 319 SUPERFAMILY SSF56655 13 317 3.42E-99 T 13-10-2018 Astex_0291 8a37b99387de7184eebc68cb64cea915 319 PIRSF PIRSF500210 3 319 5.8E-112 T 13-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 Astex_0291 8a37b99387de7184eebc68cb64cea915 319 PIRSF PIRSF000904 3 319 1.1E-110 T 13-10-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 Astex_0291 8a37b99387de7184eebc68cb64cea915 319 Gene3D G3DSA:3.40.190.80 185 319 6.8E-52 T 13-10-2018 Astex_2925 0d74d0b3b58133ddb35d9c5b8a547cbf 60 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 55 19.105 T 13-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_2925 0d74d0b3b58133ddb35d9c5b8a547cbf 60 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 55 2.9E-23 T 13-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_2925 0d74d0b3b58133ddb35d9c5b8a547cbf 60 Pfam PF01783 Ribosomal L32p protein family 2 56 4.7E-22 T 13-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_2925 0d74d0b3b58133ddb35d9c5b8a547cbf 60 SUPERFAMILY SSF57829 1 55 2.14E-20 T 13-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 Astex_0121 7b373f0e3290dfdeb37b8304a2b130da 218 Pfam PF06835 Lipopolysaccharide-assembly, LptC-related 47 203 1.4E-7 T 13-10-2018 IPR010664 Lipopolysaccharide assembly, LptC-related Astex_2660 c5aeb1df77b53a8f826bcd377049ee45 394 Gene3D G3DSA:1.10.443.10 184 362 8.9E-21 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 Astex_2660 c5aeb1df77b53a8f826bcd377049ee45 394 Gene3D G3DSA:1.10.150.130 65 172 4.3E-19 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal Astex_2660 c5aeb1df77b53a8f826bcd377049ee45 394 Pfam PF13356 Arm DNA-binding domain 1 65 2.9E-10 T 13-10-2018 IPR025166 Integrase, DNA-binding domain Astex_2660 c5aeb1df77b53a8f826bcd377049ee45 394 Gene3D G3DSA:3.30.160.390 1 64 7.4E-12 T 13-10-2018 IPR038488 Integrase, DNA-binding domain superfamily Astex_2660 c5aeb1df77b53a8f826bcd377049ee45 394 SUPERFAMILY SSF56349 74 361 2.18E-58 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 Astex_2660 c5aeb1df77b53a8f826bcd377049ee45 394 Pfam PF00589 Phage integrase family 180 351 3.0E-22 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 Astex_0880 c0c7b244e49092b122ce405bbe687517 648 Gene3D G3DSA:1.10.287.950 368 645 8.5E-47 T 13-10-2018 Astex_0880 c0c7b244e49092b122ce405bbe687517 648 Gene3D G3DSA:1.20.1480.50 168 258 1.1E-11 T 13-10-2018 Astex_0880 c0c7b244e49092b122ce405bbe687517 648 SMART SM00283 380 641 6.4E-36 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_0880 c0c7b244e49092b122ce405bbe687517 648 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 514 543 1.2E-20 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_0880 c0c7b244e49092b122ce405bbe687517 648 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 562 591 1.2E-20 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_0880 c0c7b244e49092b122ce405bbe687517 648 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 485 512 1.2E-20 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_0880 c0c7b244e49092b122ce405bbe687517 648 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 408 437 1.2E-20 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_0880 c0c7b244e49092b122ce405bbe687517 648 SUPERFAMILY SSF58104 234 640 3.14E-55 T 13-10-2018 Astex_0880 c0c7b244e49092b122ce405bbe687517 648 Pfam PF00672 HAMP domain 205 244 2.0E-6 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Astex_0880 c0c7b244e49092b122ce405bbe687517 648 SMART SM00304 386 453 93.0 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Astex_0880 c0c7b244e49092b122ce405bbe687517 648 SMART SM00304 204 257 2.4E-4 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Astex_0880 c0c7b244e49092b122ce405bbe687517 648 Gene3D G3DSA:3.30.450.20 259 367 4.2E-29 T 13-10-2018 Astex_0880 c0c7b244e49092b122ce405bbe687517 648 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 462 608 1.2E-27 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_1872 20092a97b08d4632b910854bfd508486 289 SUPERFAMILY SSF53187 12 286 9.42E-74 T 13-10-2018 Astex_1872 20092a97b08d4632b910854bfd508486 289 Pfam PF05013 N-formylglutamate amidohydrolase 26 261 2.3E-63 T 13-10-2018 IPR007709 N-formylglutamate amidohydrolase Astex_1872 20092a97b08d4632b910854bfd508486 289 Gene3D G3DSA:3.40.630.40 4 288 2.1E-89 T 13-10-2018 Astex_0085 f706a66a4d5b88817a98102c6caabdc8 322 SUPERFAMILY SSF111331 27 318 1.4E-36 T 13-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily Astex_0085 f706a66a4d5b88817a98102c6caabdc8 322 Pfam PF00781 Diacylglycerol kinase catalytic domain 28 136 5.5E-13 T 13-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 Astex_0085 f706a66a4d5b88817a98102c6caabdc8 322 Gene3D G3DSA:3.40.50.10330 16 144 1.7E-15 T 13-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 Astex_0085 f706a66a4d5b88817a98102c6caabdc8 322 Gene3D G3DSA:2.60.200.40 145 309 1.5E-13 T 13-10-2018 Astex_2780 57be37e415ecbbf32e9fb5ea72fc768e 194 SUPERFAMILY SSF55653 57 146 2.49E-24 T 13-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily Astex_2780 57be37e415ecbbf32e9fb5ea72fc768e 194 SUPERFAMILY SSF55658 1 55 2.79E-18 T 13-10-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal Astex_2780 57be37e415ecbbf32e9fb5ea72fc768e 194 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 13-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_2780 57be37e415ecbbf32e9fb5ea72fc768e 194 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 145 1.6E-39 T 13-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_2780 57be37e415ecbbf32e9fb5ea72fc768e 194 Gene3D G3DSA:3.40.5.10 1 50 2.2E-22 T 13-10-2018 IPR036935 Ribosomal protein L9, N-terminal domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_2780 57be37e415ecbbf32e9fb5ea72fc768e 194 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 45 8.6E-21 T 13-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_2780 57be37e415ecbbf32e9fb5ea72fc768e 194 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 147 24.78 T 13-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_2780 57be37e415ecbbf32e9fb5ea72fc768e 194 Gene3D G3DSA:3.10.430.100 61 147 3.2E-23 T 13-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily Astex_2780 57be37e415ecbbf32e9fb5ea72fc768e 194 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 145 1.0E-23 T 13-10-2018 IPR020069 Ribosomal protein L9, C-terminal Astex_2609 77eed8688e97114f138c28500b22c9ad 339 Pfam PF01699 Sodium/calcium exchanger protein 191 332 1.8E-31 T 13-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 Astex_2609 77eed8688e97114f138c28500b22c9ad 339 Pfam PF01699 Sodium/calcium exchanger protein 25 163 3.5E-24 T 13-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 Astex_2609 77eed8688e97114f138c28500b22c9ad 339 Gene3D G3DSA:1.20.58.1130 29 223 1.5E-82 T 13-10-2018 Astex_2609 77eed8688e97114f138c28500b22c9ad 339 TIGRFAM TIGR00367 TIGR00367: K+-dependent Na+/Ca+ exchanger homolog 25 327 8.2E-73 T 13-10-2018 IPR004481 Sodium/potassium/calcium exchanger Reactome: R-HSA-425561 Astex_2609 77eed8688e97114f138c28500b22c9ad 339 Gene3D G3DSA:1.20.1420.30 55 324 1.5E-82 T 13-10-2018 Astex_2643 4d97e1cbc966e28bf7ac00b0647e2519 377 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 220 233 - T 13-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 Astex_2643 4d97e1cbc966e28bf7ac00b0647e2519 377 Gene3D G3DSA:3.40.640.10 1 376 3.6E-115 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Astex_2643 4d97e1cbc966e28bf7ac00b0647e2519 377 Pfam PF00155 Aminotransferase class I and II 29 368 3.1E-52 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Astex_2643 4d97e1cbc966e28bf7ac00b0647e2519 377 SUPERFAMILY SSF53383 7 373 5.78E-89 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Astex_3174 b0bd7e2687501b5acd135241b73cdbbf 742 SUPERFAMILY SSF56935 42 742 7.33E-95 T 13-10-2018 Astex_3174 b0bd7e2687501b5acd135241b73cdbbf 742 Gene3D G3DSA:2.40.170.20 51 742 3.9E-114 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_3174 b0bd7e2687501b5acd135241b73cdbbf 742 Pfam PF07715 TonB-dependent Receptor Plug Domain 59 169 4.6E-11 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_3174 b0bd7e2687501b5acd135241b73cdbbf 742 Pfam PF00593 TonB dependent receptor 278 739 5.5E-33 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_3212 c27aedd6245de20bbcb921e8f6f0660d 424 SUPERFAMILY SSF51445 78 405 6.48E-62 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_3212 c27aedd6245de20bbcb921e8f6f0660d 424 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 96 398 3.3E-55 T 13-10-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 Astex_3212 c27aedd6245de20bbcb921e8f6f0660d 424 Gene3D G3DSA:3.20.20.80 81 424 6.3E-101 T 13-10-2018 Astex_0617 dcd3c70b91d52d9684cb485fcdbb2805 234 Gene3D G3DSA:3.30.565.10 96 233 2.3E-29 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_0617 dcd3c70b91d52d9684cb485fcdbb2805 234 Gene3D G3DSA:1.10.287.130 26 95 2.0E-23 T 13-10-2018 Astex_0617 dcd3c70b91d52d9684cb485fcdbb2805 234 Pfam PF10090 Histidine phosphotransferase C-terminal domain 102 223 1.3E-29 T 13-10-2018 IPR018762 Histidine phosphotransferase ChpT, C-terminal Astex_0230 058126b7c5e0a908695096aff24f1457 231 SUPERFAMILY SSF101874 49 224 1.28E-46 T 13-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily Astex_0230 058126b7c5e0a908695096aff24f1457 231 Gene3D G3DSA:2.40.128.110 48 224 2.0E-43 T 13-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily Astex_0230 058126b7c5e0a908695096aff24f1457 231 SMART SM00867 50 224 2.3E-63 T 13-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like Astex_0230 058126b7c5e0a908695096aff24f1457 231 Pfam PF04264 YceI-like domain 51 223 3.8E-38 T 13-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like Astex_0419 37c4a72b96bce1ca1e8fac72cc5f1cf7 326 Gene3D G3DSA:1.20.81.30 147 261 3.3E-10 T 13-10-2018 Astex_0419 37c4a72b96bce1ca1e8fac72cc5f1cf7 326 Pfam PF00482 Type II secretion system (T2SS), protein F 159 284 6.2E-21 T 13-10-2018 IPR018076 Type II secretion system F domain Astex_0070 a8660182861166c123ef58bbed95d4e3 399 Pfam PF00872 Transposase, Mutator family 4 371 8.0E-126 T 13-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 Astex_3530 2de5dd887e6984b6ddb36ce25512f46f 360 Gene3D G3DSA:3.20.20.70 9 264 8.4E-32 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_3530 2de5dd887e6984b6ddb36ce25512f46f 360 SUPERFAMILY SSF63892 18 259 1.06E-21 T 13-10-2018 IPR036130 Pyridoxine 5'-phosphate synthase GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 Astex_3530 2de5dd887e6984b6ddb36ce25512f46f 360 Pfam PF03740 Pyridoxal phosphate biosynthesis protein PdxJ 19 258 1.8E-37 T 13-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 Astex_1243 aa4754bb1480a1565a2fc372458a6d60 470 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 353 376 - T 13-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 Astex_1243 aa4754bb1480a1565a2fc372458a6d60 470 Hamap MF_01037 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO [trmFO]. 9 465 34.262 T 13-10-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 Astex_1243 aa4754bb1480a1565a2fc372458a6d60 470 SUPERFAMILY SSF51905 3 382 3.3E-26 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_1243 aa4754bb1480a1565a2fc372458a6d60 470 Pfam PF01134 Glucose inhibited division protein A 9 383 3.0E-103 T 13-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 Astex_1243 aa4754bb1480a1565a2fc372458a6d60 470 Gene3D G3DSA:3.50.50.60 6 184 6.5E-47 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_1243 aa4754bb1480a1565a2fc372458a6d60 470 Gene3D G3DSA:3.50.50.60 301 470 1.5E-41 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_1243 aa4754bb1480a1565a2fc372458a6d60 470 TIGRFAM TIGR00137 gid_trmFO: tRNA:m(5)U-54 methyltransferase 7 465 2.2E-165 T 13-10-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 Astex_1736 c3a278c84a409b5170e7694cf4674121 91 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 3 90 4.1E-14 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family Astex_1736 c3a278c84a409b5170e7694cf4674121 91 Gene3D G3DSA:3.30.2310.20 1 91 2.5E-18 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Astex_1016 17685705a769af64a67769b556f77e0b 380 SUPERFAMILY SSF50182 188 253 2.68E-13 T 13-10-2018 IPR010920 LSM domain superfamily Astex_1016 17685705a769af64a67769b556f77e0b 380 Pfam PF00924 Mechanosensitive ion channel 146 333 1.1E-25 T 13-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 Astex_1890 c271dc6f72473b0ad7386e70913d81da 488 Gene3D G3DSA:3.40.50.1820 3 483 9.1E-125 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1890 c271dc6f72473b0ad7386e70913d81da 488 Pfam PF00135 Carboxylesterase family 21 336 3.3E-87 T 13-10-2018 IPR002018 Carboxylesterase, type B Astex_1890 c271dc6f72473b0ad7386e70913d81da 488 Pfam PF00135 Carboxylesterase family 373 478 1.2E-6 T 13-10-2018 IPR002018 Carboxylesterase, type B Astex_1890 c271dc6f72473b0ad7386e70913d81da 488 SUPERFAMILY SSF53474 21 486 1.35E-103 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1890 c271dc6f72473b0ad7386e70913d81da 488 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 193 208 - T 13-10-2018 IPR019826 Carboxylesterase type B, active site Astex_2045 3e905fcdb7bb0f3ca381eaeaf47cabbf 329 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 242 329 5.6E-24 T 13-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 Astex_2045 3e905fcdb7bb0f3ca381eaeaf47cabbf 329 SUPERFAMILY SSF53901 5 329 6.42E-47 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 Astex_2045 3e905fcdb7bb0f3ca381eaeaf47cabbf 329 Gene3D G3DSA:3.40.47.10 2 329 3.0E-87 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 Astex_2045 3e905fcdb7bb0f3ca381eaeaf47cabbf 329 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 110 185 1.8E-16 T 13-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 Astex_2057 ef3e62d72024745ef7116b4f382e0060 172 Pfam PF07750 GcrA cell cycle regulator 1 158 3.4E-58 T 13-10-2018 IPR011681 GcrA cell cycle regulator Astex_2057 ef3e62d72024745ef7116b4f382e0060 172 Gene3D G3DSA:1.10.10.60 2 46 3.0E-8 T 13-10-2018 Astex_2687 cb1820f519a1396117fa58c12fa1095c 456 Pfam PF00672 HAMP domain 204 252 6.9E-8 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Astex_2687 cb1820f519a1396117fa58c12fa1095c 456 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 354 454 4.5E-17 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_2687 cb1820f519a1396117fa58c12fa1095c 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 387 401 4.5E-9 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_2687 cb1820f519a1396117fa58c12fa1095c 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 441 454 4.5E-9 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_2687 cb1820f519a1396117fa58c12fa1095c 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 415 4.5E-9 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_2687 cb1820f519a1396117fa58c12fa1095c 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 418 436 4.5E-9 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 Astex_2687 cb1820f519a1396117fa58c12fa1095c 456 SUPERFAMILY SSF47384 240 309 2.94E-10 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 Astex_2687 cb1820f519a1396117fa58c12fa1095c 456 SMART SM00304 203 255 3.4E-8 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Astex_2687 cb1820f519a1396117fa58c12fa1095c 456 SMART SM00387 353 456 1.2E-22 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase Astex_2687 cb1820f519a1396117fa58c12fa1095c 456 SMART SM00388 256 313 1.0E-4 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 Astex_2687 cb1820f519a1396117fa58c12fa1095c 456 Gene3D G3DSA:1.10.287.130 200 308 6.3E-17 T 13-10-2018 Astex_2687 cb1820f519a1396117fa58c12fa1095c 456 SUPERFAMILY SSF158472 204 253 2.75E-5 T 13-10-2018 Astex_2687 cb1820f519a1396117fa58c12fa1095c 456 SUPERFAMILY SSF55874 319 455 1.57E-25 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_2687 cb1820f519a1396117fa58c12fa1095c 456 Gene3D G3DSA:3.30.565.10 316 456 3.0E-25 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Astex_1360 a231e943f9358b32f418df49483ca21c 336 TIGRFAM TIGR04122 Xnuc_lig_assoc: putative exonuclease, DNA ligase-associated 7 334 2.5E-145 T 13-10-2018 IPR026360 Putative exonuclease, DNA ligase-associated Astex_1360 a231e943f9358b32f418df49483ca21c 336 Gene3D G3DSA:3.60.15.10 20 172 5.5E-22 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Astex_1360 a231e943f9358b32f418df49483ca21c 336 SUPERFAMILY SSF56281 12 318 1.04E-60 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Astex_1360 a231e943f9358b32f418df49483ca21c 336 SMART SM00849 4 177 0.0081 T 13-10-2018 IPR001279 Metallo-beta-lactamase Astex_3299 a1c4830ced9bddc3214f85f105dcbe95 397 Pfam PF00155 Aminotransferase class I and II 35 393 7.1E-64 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 Astex_3299 a1c4830ced9bddc3214f85f105dcbe95 397 SUPERFAMILY SSF53383 10 390 2.79E-92 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Astex_3299 a1c4830ced9bddc3214f85f105dcbe95 397 Gene3D G3DSA:3.90.1150.10 15 393 1.8E-131 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Astex_3299 a1c4830ced9bddc3214f85f105dcbe95 397 PRINTS PR00799 Aspartate aminotransferase signature 182 201 2.4E-26 T 13-10-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 Astex_3299 a1c4830ced9bddc3214f85f105dcbe95 397 PRINTS PR00799 Aspartate aminotransferase signature 213 225 2.4E-26 T 13-10-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 Astex_3299 a1c4830ced9bddc3214f85f105dcbe95 397 PRINTS PR00799 Aspartate aminotransferase signature 280 305 2.4E-26 T 13-10-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 Astex_3299 a1c4830ced9bddc3214f85f105dcbe95 397 PRINTS PR00799 Aspartate aminotransferase signature 342 360 2.4E-26 T 13-10-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 Astex_3299 a1c4830ced9bddc3214f85f105dcbe95 397 Gene3D G3DSA:3.40.640.10 69 307 1.8E-131 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Astex_0177 2296f9168563ae67c1db120fa3cb8cbb 242 Gene3D G3DSA:3.30.1230.10 25 116 1.4E-12 T 13-10-2018 IPR035931 YlxR-like superfamily Astex_0177 2296f9168563ae67c1db120fa3cb8cbb 242 SUPERFAMILY SSF64376 33 118 7.98E-19 T 13-10-2018 IPR035931 YlxR-like superfamily Astex_0177 2296f9168563ae67c1db120fa3cb8cbb 242 SUPERFAMILY SSF55315 116 211 7.3E-9 T 13-10-2018 IPR029064 50S ribosomal protein L30e-like Astex_0177 2296f9168563ae67c1db120fa3cb8cbb 242 Pfam PF04296 Protein of unknown function (DUF448) 35 103 1.4E-15 T 13-10-2018 IPR007393 Domain of unknown function DUF448 Astex_0177 2296f9168563ae67c1db120fa3cb8cbb 242 Gene3D G3DSA:3.30.1330.30 117 220 1.4E-7 T 13-10-2018 IPR029064 50S ribosomal protein L30e-like Astex_3777 8c8d46c51220b7803c5fa19ada4464ee 401 Pfam PF10134 Replication initiator protein A 83 313 6.0E-80 T 13-10-2018 IPR018777 Replication initiator protein A Astex_0290 85ee7fb9966516646b8e155cc313b7fd 474 SUPERFAMILY SSF109604 280 449 1.46E-34 T 13-10-2018 Astex_0290 85ee7fb9966516646b8e155cc313b7fd 474 Gene3D G3DSA:1.10.3210.10 14 91 2.3E-5 T 13-10-2018 Astex_0290 85ee7fb9966516646b8e155cc313b7fd 474 Gene3D G3DSA:1.10.3210.10 266 458 5.4E-59 T 13-10-2018 Astex_0290 85ee7fb9966516646b8e155cc313b7fd 474 Gene3D G3DSA:1.10.3210.10 127 239 1.8E-17 T 13-10-2018 Astex_0290 85ee7fb9966516646b8e155cc313b7fd 474 Pfam PF13487 HD domain 339 401 7.0E-18 T 13-10-2018 Astex_0290 85ee7fb9966516646b8e155cc313b7fd 474 Pfam PF13487 HD domain 138 192 1.0E-8 T 13-10-2018 Astex_0290 85ee7fb9966516646b8e155cc313b7fd 474 SMART SM00471 284 419 2.5E-10 T 13-10-2018 IPR003607 HD/PDEase domain Astex_0290 85ee7fb9966516646b8e155cc313b7fd 474 SUPERFAMILY SSF109604 20 234 6.11E-11 T 13-10-2018 Astex_2022 17c9173b1c35f71565cb49a72216f548 164 Hamap MF_00676 UPF0260 protein YcgN [ycgN]. 10 156 39.403 T 13-10-2018 IPR008228 Uncharacterised conserved protein UCP006173 Astex_2022 17c9173b1c35f71565cb49a72216f548 164 PIRSF PIRSF006173 6 153 1.0E-63 T 13-10-2018 IPR008228 Uncharacterised conserved protein UCP006173 Astex_2022 17c9173b1c35f71565cb49a72216f548 164 Pfam PF03692 Putative zinc- or iron-chelating domain 32 100 2.6E-9 T 13-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein Astex_2495 ffb41a6aa1d872cab788d9cd7129e118 600 Pfam PF05960 Bacterial protein of unknown function (DUF885) 49 591 4.0E-157 T 13-10-2018 IPR010281 Protein of unknown function DUF885 Astex_2763 81a7bc6f89800971f202efb3b1e52ca8 249 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 2 243 1.2E-106 T 13-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 Astex_2763 81a7bc6f89800971f202efb3b1e52ca8 249 SUPERFAMILY SSF52540 2 242 3.27E-44 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2763 81a7bc6f89800971f202efb3b1e52ca8 249 SMART SM00382 26 223 1.8E-4 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_2763 81a7bc6f89800971f202efb3b1e52ca8 249 Pfam PF00005 ABC transporter 17 172 5.4E-19 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_2763 81a7bc6f89800971f202efb3b1e52ca8 249 Gene3D G3DSA:3.40.50.300 1 248 4.4E-59 T 13-10-2018 Astex_2763 81a7bc6f89800971f202efb3b1e52ca8 249 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Astex_3820 c7fbbb051a4115d647edc8495cf48089 333 Pfam PF01758 Sodium Bile acid symporter family 47 238 8.2E-43 T 13-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 Astex_3820 c7fbbb051a4115d647edc8495cf48089 333 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 1 326 3.3E-115 T 13-10-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 Astex_3820 c7fbbb051a4115d647edc8495cf48089 333 Gene3D G3DSA:1.20.1530.20 1 328 7.0E-26 T 13-10-2018 IPR038770 Sodium/solute symporter superfamily Astex_3820 c7fbbb051a4115d647edc8495cf48089 333 PIRSF PIRSF005508 1 333 1.1E-114 T 13-10-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 Astex_3468 8dd2d234a4cc6904a74d15cffd4c743f 204 Pfam PF06445 GyrI-like small molecule binding domain 21 198 7.3E-24 T 13-10-2018 IPR029442 GyrI-like small molecule binding domain Astex_3468 8dd2d234a4cc6904a74d15cffd4c743f 204 PIRSF PIRSF031644 1 204 2.6E-59 T 13-10-2018 IPR008319 Uncharacterised conserved protein UCP031644 Astex_3468 8dd2d234a4cc6904a74d15cffd4c743f 204 Gene3D G3DSA:3.20.80.10 1 202 6.4E-74 T 13-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily Astex_3468 8dd2d234a4cc6904a74d15cffd4c743f 204 SUPERFAMILY SSF55136 123 195 7.06E-9 T 13-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily Astex_1355 3f8d35e8ffcdeaef99514167e6333b4c 363 SUPERFAMILY SSF51445 13 298 7.48E-65 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_1355 3f8d35e8ffcdeaef99514167e6333b4c 363 Gene3D G3DSA:3.20.20.300 10 354 5.8E-91 T 13-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 Astex_1355 3f8d35e8ffcdeaef99514167e6333b4c 363 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 37 318 1.6E-50 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_1355 3f8d35e8ffcdeaef99514167e6333b4c 363 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 245 262 - T 13-10-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 Astex_2437 96c7f8f478a1c075a5e2eeb043791813 821 Pfam PF13271 Domain of unknown function (DUF4062) 8 102 1.8E-6 T 13-10-2018 IPR025139 Domain of unknown function DUF4062 Astex_0425 d3c68cf269541b382eef2beea8a2dc3e 171 Gene3D G3DSA:1.20.120.1220 4 138 1.2E-7 T 13-10-2018 Astex_0425 d3c68cf269541b382eef2beea8a2dc3e 171 Pfam PF01478 Type IV leader peptidase family 10 111 1.1E-12 T 13-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 Astex_2654 96c7be4427e40f08677caa971dd2fade 129 SUPERFAMILY SSF161084 4 125 1.16E-22 T 13-10-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamily Astex_2654 96c7be4427e40f08677caa971dd2fade 129 Pfam PF01124 MAPEG family 9 128 1.0E-16 T 13-10-2018 IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein Astex_2654 96c7be4427e40f08677caa971dd2fade 129 Gene3D G3DSA:1.20.120.550 3 129 3.7E-17 T 13-10-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamily Astex_0385 96a2dfec3e0d54ce487775d450d6f8b4 285 SUPERFAMILY SSF53474 23 281 8.71E-37 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_0385 96a2dfec3e0d54ce487775d450d6f8b4 285 Gene3D G3DSA:3.40.50.1820 55 282 1.7E-34 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_0385 96a2dfec3e0d54ce487775d450d6f8b4 285 Pfam PF12146 Serine aminopeptidase, S33 104 197 1.3E-7 T 13-10-2018 IPR022742 Serine aminopeptidase, S33 Astex_3091 a684b13be1fecad9a060a4805096aaae 180 Pfam PF13628 Domain of unknown function (DUF4142) 37 167 9.3E-11 T 13-10-2018 IPR025419 Domain of unknown function DUF4142 Astex_0152 560e2eb60a48005ba446691022ea7e69 232 TIGRFAM TIGR01406 dnaQ_proteo: DNA polymerase III, epsilon subunit 2 227 8.2E-78 T 13-10-2018 IPR006309 DNA polymerase 3, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Astex_0152 560e2eb60a48005ba446691022ea7e69 232 Gene3D G3DSA:3.30.420.10 1 172 9.4E-55 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Astex_0152 560e2eb60a48005ba446691022ea7e69 232 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 4 174 8.0E-47 T 13-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 Astex_0152 560e2eb60a48005ba446691022ea7e69 232 SMART SM00479 2 172 2.1E-48 T 13-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III Astex_0152 560e2eb60a48005ba446691022ea7e69 232 SUPERFAMILY SSF53098 1 168 1.1E-55 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily Astex_0152 560e2eb60a48005ba446691022ea7e69 232 Pfam PF00929 Exonuclease 4 163 1.4E-36 T 13-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III Astex_1784 8eecada893a4a3bef6ac3fb3815465e7 352 Pfam PF01594 AI-2E family transporter 17 328 1.9E-49 T 13-10-2018 IPR002549 Transmembrane protein TqsA-like Astex_1652 bfd1f54c6c402c26c7bd13c5c2c9ddbb 397 SUPERFAMILY SSF53748 3 396 8.6E-140 T 13-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_1652 bfd1f54c6c402c26c7bd13c5c2c9ddbb 397 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 5 397 36.633 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_1652 bfd1f54c6c402c26c7bd13c5c2c9ddbb 397 Pfam PF00162 Phosphoglycerate kinase 7 388 5.0E-139 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_1652 bfd1f54c6c402c26c7bd13c5c2c9ddbb 397 Gene3D G3DSA:3.40.50.1260 11 396 1.5E-140 T 13-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_1652 bfd1f54c6c402c26c7bd13c5c2c9ddbb 397 PRINTS PR00477 Phosphoglycerate kinase family signature 374 391 2.6E-77 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_1652 bfd1f54c6c402c26c7bd13c5c2c9ddbb 397 PRINTS PR00477 Phosphoglycerate kinase family signature 138 160 2.6E-77 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_1652 bfd1f54c6c402c26c7bd13c5c2c9ddbb 397 PRINTS PR00477 Phosphoglycerate kinase family signature 351 362 2.6E-77 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_1652 bfd1f54c6c402c26c7bd13c5c2c9ddbb 397 PRINTS PR00477 Phosphoglycerate kinase family signature 168 190 2.6E-77 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_1652 bfd1f54c6c402c26c7bd13c5c2c9ddbb 397 PRINTS PR00477 Phosphoglycerate kinase family signature 191 210 2.6E-77 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_1652 bfd1f54c6c402c26c7bd13c5c2c9ddbb 397 PRINTS PR00477 Phosphoglycerate kinase family signature 110 125 2.6E-77 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_1652 bfd1f54c6c402c26c7bd13c5c2c9ddbb 397 PRINTS PR00477 Phosphoglycerate kinase family signature 314 339 2.6E-77 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_1652 bfd1f54c6c402c26c7bd13c5c2c9ddbb 397 PRINTS PR00477 Phosphoglycerate kinase family signature 32 54 2.6E-77 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_1652 bfd1f54c6c402c26c7bd13c5c2c9ddbb 397 PRINTS PR00477 Phosphoglycerate kinase family signature 11 27 2.6E-77 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_1652 bfd1f54c6c402c26c7bd13c5c2c9ddbb 397 Gene3D G3DSA:3.40.50.1260 170 388 1.5E-140 T 13-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_1652 bfd1f54c6c402c26c7bd13c5c2c9ddbb 397 PIRSF PIRSF000724 1 397 1.6E-131 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 Astex_1209 22813b4fd35d3b55f962f24e6ae808dd 299 Pfam PF01882 Protein of unknown function DUF58 41 129 1.3E-20 T 13-10-2018 IPR002881 Domain of unknown function DUF58 Astex_1209 22813b4fd35d3b55f962f24e6ae808dd 299 SUPERFAMILY SSF53300 77 217 3.46E-12 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Astex_1209 22813b4fd35d3b55f962f24e6ae808dd 299 Gene3D G3DSA:3.40.50.410 77 267 4.0E-8 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Astex_1163 dba3f838b6dd84a9648f525cb2dd8baf 149 SMART SM00347 33 132 1.6E-20 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Astex_1163 dba3f838b6dd84a9648f525cb2dd8baf 149 Pfam PF01047 MarR family 40 97 1.1E-14 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Astex_1163 dba3f838b6dd84a9648f525cb2dd8baf 149 SUPERFAMILY SSF46785 10 141 1.03E-32 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_1163 dba3f838b6dd84a9648f525cb2dd8baf 149 Gene3D G3DSA:1.10.10.10 7 147 1.3E-34 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1163 dba3f838b6dd84a9648f525cb2dd8baf 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 93 109 5.1E-8 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Astex_1163 dba3f838b6dd84a9648f525cb2dd8baf 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 89 5.1E-8 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Astex_1163 dba3f838b6dd84a9648f525cb2dd8baf 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 57 73 5.1E-8 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Astex_0611 78893312d65c00030f8dfef95bbb3b71 118 Gene3D G3DSA:1.10.10.10 5 104 8.5E-15 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_0611 78893312d65c00030f8dfef95bbb3b71 118 SUPERFAMILY SSF46785 6 97 4.5E-17 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_0611 78893312d65c00030f8dfef95bbb3b71 118 SMART SM00418 14 94 3.4E-12 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 Astex_0611 78893312d65c00030f8dfef95bbb3b71 118 Pfam PF12840 Helix-turn-helix domain 15 74 4.1E-9 T 13-10-2018 Astex_2991 65dda6c7e0aa03e918afc948024636be 409 Pfam PF13229 Right handed beta helix region 149 303 4.2E-7 T 13-10-2018 IPR039448 Right handed beta helix domain Astex_2991 65dda6c7e0aa03e918afc948024636be 409 SUPERFAMILY SSF51126 7 343 3.55E-35 T 13-10-2018 IPR011050 Pectin lyase fold/virulence factor Astex_1353 84155cc47ffc2cf07a63ac11d0278802 223 SUPERFAMILY SSF46785 9 78 6.26E-14 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_1353 84155cc47ffc2cf07a63ac11d0278802 223 Gene3D G3DSA:1.10.10.10 80 177 2.7E-31 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1353 84155cc47ffc2cf07a63ac11d0278802 223 SUPERFAMILY SSF46785 84 159 3.78E-25 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_1353 84155cc47ffc2cf07a63ac11d0278802 223 PIRSF PIRSF019345 2 200 4.2E-50 T 13-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 Astex_1353 84155cc47ffc2cf07a63ac11d0278802 223 Pfam PF04079 Segregation and condensation complex subunit ScpB 14 166 2.8E-49 T 13-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 Astex_1353 84155cc47ffc2cf07a63ac11d0278802 223 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 12 171 9.4E-31 T 13-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 Astex_1353 84155cc47ffc2cf07a63ac11d0278802 223 Gene3D G3DSA:1.10.10.10 6 79 4.1E-11 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1524 b878e273698b635dbd290b78741afbc2 148 SUPERFAMILY SSF54637 24 144 6.1E-26 T 13-10-2018 IPR029069 HotDog domain superfamily Astex_1524 b878e273698b635dbd290b78741afbc2 148 Pfam PF03061 Thioesterase superfamily 58 133 1.9E-14 T 13-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 Astex_1524 b878e273698b635dbd290b78741afbc2 148 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 41 126 1.3E-12 T 13-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 Astex_1524 b878e273698b635dbd290b78741afbc2 148 Gene3D G3DSA:3.10.129.10 13 145 7.3E-38 T 13-10-2018 Astex_0037 50cf99991493e56991d651cdb96df81f 567 Pfam PF13000 Acetyl-coenzyme A transporter 1 29 150 2.5E-10 T 13-10-2018 IPR024371 Acetyl-coenzyme A transporter 1-like GO:0008521|GO:0016021 Reactome: R-HSA-425397|Reactome: R-HSA-5619061 Astex_0037 50cf99991493e56991d651cdb96df81f 567 SUPERFAMILY SSF103473 13 557 1.02E-17 T 13-10-2018 IPR036259 MFS transporter superfamily Astex_0037 50cf99991493e56991d651cdb96df81f 567 Gene3D G3DSA:1.20.1250.20 17 217 9.9E-9 T 13-10-2018 Astex_2760 0ec62c27f0e31048b44a62f531f481e6 374 Gene3D G3DSA:3.90.1150.10 7 353 2.9E-102 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Astex_2760 0ec62c27f0e31048b44a62f531f481e6 374 SUPERFAMILY SSF53383 6 355 2.99E-79 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Astex_2760 0ec62c27f0e31048b44a62f531f481e6 374 PIRSF PIRSF005572 3 366 7.1E-102 T 13-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 Astex_2760 0ec62c27f0e31048b44a62f531f481e6 374 Gene3D G3DSA:3.40.640.10 63 230 2.9E-102 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Astex_2760 0ec62c27f0e31048b44a62f531f481e6 374 Pfam PF00266 Aminotransferase class-V 7 347 7.6E-55 T 13-10-2018 IPR000192 Aminotransferase class V domain Astex_2760 0ec62c27f0e31048b44a62f531f481e6 374 Gene3D G3DSA:1.10.260.50 17 266 2.9E-102 T 13-10-2018 Astex_3372 28ccbb653aa43408a06cff19734576ac 283 SUPERFAMILY SSF161098 32 272 6.11E-30 T 13-10-2018 IPR035906 MetI-like superfamily Astex_3372 28ccbb653aa43408a06cff19734576ac 283 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 278 1.2E-19 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Astex_3372 28ccbb653aa43408a06cff19734576ac 283 Gene3D G3DSA:1.10.3720.10 63 282 2.3E-26 T 13-10-2018 IPR035906 MetI-like superfamily Astex_3372 28ccbb653aa43408a06cff19734576ac 283 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 16 280 9.3E-71 T 13-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 Astex_1831 1d882ee5ec83f1924fff0c8f2a4cbf5d 66 Pfam PF11324 Protein of unknown function (DUF3126) 5 65 5.6E-27 T 13-10-2018 IPR021473 Protein of unknown function DUF3126 Astex_1669 85bd04c34103d56d1c2b666f7306546f 569 SUPERFAMILY SSF52540 1 219 1.34E-55 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1669 85bd04c34103d56d1c2b666f7306546f 569 Pfam PF02463 RecF/RecN/SMC N terminal domain 14 526 1.8E-13 T 13-10-2018 IPR003395 RecF/RecN/SMC, N-terminal Astex_1669 85bd04c34103d56d1c2b666f7306546f 569 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 568 1.1E-124 T 13-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 Astex_1669 85bd04c34103d56d1c2b666f7306546f 569 PIRSF PIRSF003128 1 569 2.0E-138 T 13-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 Astex_1669 85bd04c34103d56d1c2b666f7306546f 569 Gene3D G3DSA:3.40.50.300 324 569 2.1E-41 T 13-10-2018 Astex_1669 85bd04c34103d56d1c2b666f7306546f 569 SUPERFAMILY SSF52540 2 521 1.63E-24 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1669 85bd04c34103d56d1c2b666f7306546f 569 Gene3D G3DSA:3.40.50.300 1 305 2.0E-38 T 13-10-2018 Astex_0381 d1823cf74ef87902f30fcb54b7c30cfa 305 TIGRFAM TIGR00688 rarD: protein RarD 25 268 1.7E-50 T 13-10-2018 IPR004626 RarD protein GO:0005887 Astex_0381 d1823cf74ef87902f30fcb54b7c30cfa 305 SUPERFAMILY SSF103481 75 153 1.44E-8 T 13-10-2018 Astex_2863 a288137f405818eda673e85eb69021c3 264 Pfam PF00218 Indole-3-glycerol phosphate synthase 5 260 1.9E-89 T 13-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 Astex_2863 a288137f405818eda673e85eb69021c3 264 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 56 74 - T 13-10-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 Astex_2863 a288137f405818eda673e85eb69021c3 264 SUPERFAMILY SSF51366 12 261 5.56E-82 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Astex_2863 a288137f405818eda673e85eb69021c3 264 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 3 262 34.547 T 13-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 Astex_2863 a288137f405818eda673e85eb69021c3 264 Gene3D G3DSA:3.20.20.70 1 264 1.4E-97 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_1215 4e329f1b4e8a155607e9c3369f7d441f 969 Gene3D G3DSA:2.40.170.20 279 969 5.5E-35 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_1215 4e329f1b4e8a155607e9c3369f7d441f 969 Pfam PF00593 TonB dependent receptor 361 968 1.2E-16 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_1215 4e329f1b4e8a155607e9c3369f7d441f 969 SUPERFAMILY SSF56935 112 969 2.71E-65 T 13-10-2018 Astex_1215 4e329f1b4e8a155607e9c3369f7d441f 969 SUPERFAMILY SSF49452 31 110 2.35E-10 T 13-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 Astex_1215 4e329f1b4e8a155607e9c3369f7d441f 969 Pfam PF13620 Carboxypeptidase regulatory-like domain 39 112 1.7E-10 T 13-10-2018 Astex_1215 4e329f1b4e8a155607e9c3369f7d441f 969 Gene3D G3DSA:2.60.40.10 35 144 1.1E-8 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_0148 e75a1a74afa77a10fdc49eb61204a022 331 Pfam PF03618 Kinase/pyrophosphorylase 58 317 1.8E-87 T 13-10-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 Astex_0148 e75a1a74afa77a10fdc49eb61204a022 331 Hamap MF_00921 Putative pyruvate, phosphate dikinase regulatory protein. 56 322 54.788 T 13-10-2018 IPR026565 Putative pyruvate, phosphate dikinase regulatory protein Astex_3224 b97aca3b848ea9bb0ffbce71d0f1c1b9 756 Gene3D G3DSA:2.60.40.10 626 743 5.6E-29 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_3224 b97aca3b848ea9bb0ffbce71d0f1c1b9 756 PRINTS PR00133 Glycosyl hydrolase family 3 signature 278 296 2.8E-28 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_3224 b97aca3b848ea9bb0ffbce71d0f1c1b9 756 PRINTS PR00133 Glycosyl hydrolase family 3 signature 131 150 2.8E-28 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_3224 b97aca3b848ea9bb0ffbce71d0f1c1b9 756 PRINTS PR00133 Glycosyl hydrolase family 3 signature 208 224 2.8E-28 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_3224 b97aca3b848ea9bb0ffbce71d0f1c1b9 756 PRINTS PR00133 Glycosyl hydrolase family 3 signature 177 193 2.8E-28 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_3224 b97aca3b848ea9bb0ffbce71d0f1c1b9 756 PRINTS PR00133 Glycosyl hydrolase family 3 signature 106 122 2.8E-28 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_3224 b97aca3b848ea9bb0ffbce71d0f1c1b9 756 Gene3D G3DSA:3.40.50.1700 368 625 7.0E-71 T 13-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 Astex_3224 b97aca3b848ea9bb0ffbce71d0f1c1b9 756 SUPERFAMILY SSF51445 35 381 3.9E-87 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_3224 b97aca3b848ea9bb0ffbce71d0f1c1b9 756 Pfam PF14310 Fibronectin type III-like domain 662 731 1.6E-19 T 13-10-2018 IPR026891 Fibronectin type III-like domain Astex_3224 b97aca3b848ea9bb0ffbce71d0f1c1b9 756 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 382 625 1.1E-53 T 13-10-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 Astex_3224 b97aca3b848ea9bb0ffbce71d0f1c1b9 756 Gene3D G3DSA:3.20.20.300 23 355 2.4E-93 T 13-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 Astex_3224 b97aca3b848ea9bb0ffbce71d0f1c1b9 756 SUPERFAMILY SSF52279 382 628 2.88E-48 T 13-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 Astex_3224 b97aca3b848ea9bb0ffbce71d0f1c1b9 756 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 106 347 1.1E-44 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 Astex_3224 b97aca3b848ea9bb0ffbce71d0f1c1b9 756 SMART SM01217 661 731 3.8E-23 T 13-10-2018 IPR026891 Fibronectin type III-like domain Astex_3296 d4c0e1632a7892f552531c9c5ede407a 424 Hamap MF_00334 Homogentisate 1,2-dioxygenase [hmgA]. 3 424 70.03 T 13-10-2018 IPR022950 Homogentisate 1,2-dioxygenase, bacterial GO:0004411|GO:0006559|GO:0006572|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5 Astex_3296 d4c0e1632a7892f552531c9c5ede407a 424 SUPERFAMILY SSF51182 3 420 1.18E-162 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily Astex_3296 d4c0e1632a7892f552531c9c5ede407a 424 Gene3D G3DSA:2.60.120.10 266 392 1.0E-62 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Astex_3296 d4c0e1632a7892f552531c9c5ede407a 424 TIGRFAM TIGR01015 hmgA: homogentisate 1,2-dioxygenase 4 421 3.0E-203 T 13-10-2018 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 Astex_3296 d4c0e1632a7892f552531c9c5ede407a 424 Pfam PF04209 homogentisate 1,2-dioxygenase 4 420 2.0E-205 T 13-10-2018 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 Astex_0209 15f182dc20cb33992c9126c919e972b1 124 TIGRFAM TIGR02968 succ_dehyd_anc: succinate dehydrogenase, hydrophobic membrane anchor protein 19 115 6.7E-13 T 13-10-2018 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 Astex_0209 15f182dc20cb33992c9126c919e972b1 124 Gene3D G3DSA:1.20.1300.10 11 123 1.3E-18 T 13-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Astex_0209 15f182dc20cb33992c9126c919e972b1 124 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 16 113 2.7E-8 T 13-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Astex_0209 15f182dc20cb33992c9126c919e972b1 124 SUPERFAMILY SSF81343 16 119 1.08E-14 T 13-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Astex_1620 e7da344ee0811ec9f1ecd7889a4b54b9 279 Gene3D G3DSA:3.40.50.720 1 274 2.0E-84 T 13-10-2018 Astex_1620 e7da344ee0811ec9f1ecd7889a4b54b9 279 SUPERFAMILY SSF51735 4 275 5.83E-30 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_0420 3cbbffeb06efa1289bf95091c550a1ca 538 SUPERFAMILY SSF52540 168 473 3.46E-63 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0420 3cbbffeb06efa1289bf95091c550a1ca 538 Gene3D G3DSA:3.40.50.300 283 524 2.9E-71 T 13-10-2018 Astex_0420 3cbbffeb06efa1289bf95091c550a1ca 538 Pfam PF00437 Type II/IV secretion system protein 187 462 7.8E-80 T 13-10-2018 IPR001482 Type II/IV secretion system protein Astex_0420 3cbbffeb06efa1289bf95091c550a1ca 538 Gene3D G3DSA:3.30.450.380 99 281 2.1E-44 T 13-10-2018 Astex_1403 5d77e3fc2012b60a4e5b36971c32a2f4 79 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 9 49 4.0E-11 T 13-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 Astex_1403 5d77e3fc2012b60a4e5b36971c32a2f4 79 Pfam PF02609 Exonuclease VII small subunit 10 61 3.5E-19 T 13-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 Astex_1403 5d77e3fc2012b60a4e5b36971c32a2f4 79 PIRSF PIRSF006488 1 79 1.0E-21 T 13-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 Astex_1403 5d77e3fc2012b60a4e5b36971c32a2f4 79 SUPERFAMILY SSF116842 3 67 1.26E-19 T 13-10-2018 Astex_1403 5d77e3fc2012b60a4e5b36971c32a2f4 79 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 9 69 14.944 T 13-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 Astex_1403 5d77e3fc2012b60a4e5b36971c32a2f4 79 Gene3D G3DSA:1.10.287.1040 4 77 3.7E-21 T 13-10-2018 IPR037004 Exonuclease VII, small subunit superfamily GO:0006308|GO:0008855|GO:0009318 Astex_1403 5d77e3fc2012b60a4e5b36971c32a2f4 79 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 9 62 4.1E-22 T 13-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 Astex_3595 fc89274d3607b84924c3217fbf8ac5a6 1102 SUPERFAMILY SSF56935 42 1101 1.67E-50 T 13-10-2018 Astex_3595 fc89274d3607b84924c3217fbf8ac5a6 1102 Pfam PF07715 TonB-dependent Receptor Plug Domain 58 166 3.9E-13 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_3595 fc89274d3607b84924c3217fbf8ac5a6 1102 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 40 1102 1.8E-127 T 13-10-2018 IPR010104 Bacterial TonB-dependent receptor Astex_3595 fc89274d3607b84924c3217fbf8ac5a6 1102 Pfam PF00593 TonB dependent receptor 489 1098 2.1E-15 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_3595 fc89274d3607b84924c3217fbf8ac5a6 1102 Gene3D G3DSA:2.170.130.10 31 170 2.5E-13 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_2286 b51e6b538a03c6b97fb0049d44e27878 286 Hamap MF_00056 2-dehydro-3-deoxyphosphooctonate aldolase [kdsA]. 17 279 53.816 T 13-10-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 Astex_2286 b51e6b538a03c6b97fb0049d44e27878 286 Gene3D G3DSA:3.20.20.70 5 283 4.8E-101 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_2286 b51e6b538a03c6b97fb0049d44e27878 286 SUPERFAMILY SSF51569 8 278 3.94E-106 T 13-10-2018 Astex_2286 b51e6b538a03c6b97fb0049d44e27878 286 Pfam PF00793 DAHP synthetase I family 15 263 6.5E-66 T 13-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 Astex_2286 b51e6b538a03c6b97fb0049d44e27878 286 TIGRFAM TIGR01362 KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase 23 277 1.5E-123 T 13-10-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 Astex_2707 ab8f6f2f5154312730c1880212189f99 546 Pfam PF03572 Peptidase family S41 269 419 1.6E-15 T 13-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 Astex_2707 ab8f6f2f5154312730c1880212189f99 546 Gene3D G3DSA:3.90.226.10 254 490 1.2E-63 T 13-10-2018 Astex_2707 ab8f6f2f5154312730c1880212189f99 546 SUPERFAMILY SSF52096 261 458 3.15E-28 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Astex_2707 ab8f6f2f5154312730c1880212189f99 546 Gene3D G3DSA:3.30.750.170 99 448 1.2E-63 T 13-10-2018 Astex_2707 ab8f6f2f5154312730c1880212189f99 546 Gene3D G3DSA:2.30.42.10 149 253 1.2E-63 T 13-10-2018 Astex_1934 4697d154900b9c40dfbdf640144ed75a 225 Gene3D G3DSA:1.10.3720.10 1 217 7.9E-47 T 13-10-2018 IPR035906 MetI-like superfamily Astex_1934 4697d154900b9c40dfbdf640144ed75a 225 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 7 214 2.7E-64 T 13-10-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 Astex_1934 4697d154900b9c40dfbdf640144ed75a 225 SUPERFAMILY SSF161098 1 211 2.49E-40 T 13-10-2018 IPR035906 MetI-like superfamily Astex_1934 4697d154900b9c40dfbdf640144ed75a 225 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 24 213 6.0E-17 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Astex_3523 db3d118db3555502d2a44970c6c2f35b 419 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 207 402 4.9E-25 T 13-10-2018 IPR013830 SGNH hydrolase-type esterase domain Astex_3523 db3d118db3555502d2a44970c6c2f35b 419 SUPERFAMILY SSF52266 202 408 5.8E-40 T 13-10-2018 Astex_3523 db3d118db3555502d2a44970c6c2f35b 419 Gene3D G3DSA:3.40.50.1110 193 409 6.8E-33 T 13-10-2018 IPR036514 SGNH hydrolase superfamily Astex_0734 f9800bc2b06a90a6c03a2ea22209efaf 208 TIGRFAM TIGR03072 release_prfH: putative peptide chain release factor H 4 201 1.1E-67 T 13-10-2018 IPR017509 Putative peptide chain release factor H Astex_0734 f9800bc2b06a90a6c03a2ea22209efaf 208 Gene3D G3DSA:3.30.70.1660 6 198 3.4E-34 T 13-10-2018 Astex_0734 f9800bc2b06a90a6c03a2ea22209efaf 208 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 116 132 - T 13-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 Astex_0734 f9800bc2b06a90a6c03a2ea22209efaf 208 Pfam PF00472 RF-1 domain 104 197 2.1E-26 T 13-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 Astex_0734 f9800bc2b06a90a6c03a2ea22209efaf 208 Gene3D G3DSA:3.30.160.20 99 192 3.4E-34 T 13-10-2018 Astex_0734 f9800bc2b06a90a6c03a2ea22209efaf 208 SUPERFAMILY SSF75620 3 200 5.49E-51 T 13-10-2018 Astex_0013 3ce041716a1f6a0132c4592e07419c2b 229 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 8 222 3.3E-38 T 13-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Astex_0013 3ce041716a1f6a0132c4592e07419c2b 229 SUPERFAMILY SSF51366 7 226 7.23E-59 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 Astex_0013 3ce041716a1f6a0132c4592e07419c2b 229 Gene3D G3DSA:3.20.20.70 4 228 1.6E-72 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_0013 3ce041716a1f6a0132c4592e07419c2b 229 SMART SM00934 8 223 3.2E-66 T 13-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Astex_0013 3ce041716a1f6a0132c4592e07419c2b 229 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 10 223 3.8E-45 T 13-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Astex_0013 3ce041716a1f6a0132c4592e07419c2b 229 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 6 228 31.858 T 13-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 Astex_2029 2de569663d90b66bfc4692fc1e85e16a 258 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 256 7.6E-52 T 13-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 Astex_2029 2de569663d90b66bfc4692fc1e85e16a 258 Gene3D G3DSA:3.90.226.10 3 195 4.2E-64 T 13-10-2018 Astex_2029 2de569663d90b66bfc4692fc1e85e16a 258 Gene3D G3DSA:1.10.12.10 201 258 1.9E-20 T 13-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal Astex_2029 2de569663d90b66bfc4692fc1e85e16a 258 SUPERFAMILY SSF52096 2 256 5.83E-75 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Astex_3665 b1f53cc2eaa103f544536b2d3a5bc415 297 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 248 270 5.7E-12 T 13-10-2018 Astex_3665 b1f53cc2eaa103f544536b2d3a5bc415 297 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 5.7E-12 T 13-10-2018 Astex_3665 b1f53cc2eaa103f544536b2d3a5bc415 297 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 5.7E-12 T 13-10-2018 Astex_3665 b1f53cc2eaa103f544536b2d3a5bc415 297 SUPERFAMILY SSF51905 3 290 7.95E-31 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_3665 b1f53cc2eaa103f544536b2d3a5bc415 297 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 284 3.9E-21 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Astex_3665 b1f53cc2eaa103f544536b2d3a5bc415 297 Gene3D G3DSA:3.50.50.60 4 289 4.5E-83 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_3665 b1f53cc2eaa103f544536b2d3a5bc415 297 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 6.3E-6 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Astex_3665 b1f53cc2eaa103f544536b2d3a5bc415 297 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 101 109 6.3E-6 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Astex_3665 b1f53cc2eaa103f544536b2d3a5bc415 297 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 123 135 6.3E-6 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Astex_3665 b1f53cc2eaa103f544536b2d3a5bc415 297 Gene3D G3DSA:3.50.50.60 114 224 4.5E-83 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_3779 39bddc81dddb609df39a00bd67b2edc0 270 Gene3D G3DSA:1.10.530.10 72 269 2.8E-46 T 13-10-2018 Astex_3779 39bddc81dddb609df39a00bd67b2edc0 270 SUPERFAMILY SSF53955 85 145 2.95E-8 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily Astex_0190 dd2ff3a9e3764ac640753d7d26ffc77e 376 Gene3D G3DSA:2.120.10.30 31 376 8.9E-118 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like Astex_0190 dd2ff3a9e3764ac640753d7d26ffc77e 376 Pfam PF07995 Glucose / Sorbosone dehydrogenase 46 372 2.2E-131 T 13-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase Astex_0190 dd2ff3a9e3764ac640753d7d26ffc77e 376 SUPERFAMILY SSF50952 34 373 6.28E-51 T 13-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 Astex_0042 0499a70d0465046846aa185b2187c671 424 Gene3D G3DSA:2.40.420.20 52 382 1.1E-93 T 13-10-2018 Astex_0042 0499a70d0465046846aa185b2187c671 424 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 66 273 2.0E-14 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain Astex_0042 0499a70d0465046846aa185b2187c671 424 SUPERFAMILY SSF111369 60 256 3.4E-24 T 13-10-2018 Astex_0042 0499a70d0465046846aa185b2187c671 424 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 53 383 5.4E-55 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 Astex_0042 0499a70d0465046846aa185b2187c671 424 Gene3D G3DSA:2.40.50.100 68 230 1.1E-93 T 13-10-2018 Astex_0042 0499a70d0465046846aa185b2187c671 424 Gene3D G3DSA:2.40.30.170 57 320 1.1E-93 T 13-10-2018 Astex_0042 0499a70d0465046846aa185b2187c671 424 Gene3D G3DSA:1.10.287.470 102 193 1.1E-93 T 13-10-2018 Astex_2946 a09b5299ee65e793ed07f146823c4da8 71 Pfam PF09720 Putative addiction module component 12 61 2.8E-19 T 13-10-2018 IPR013406 Conserved hypothetical protein CHP02574, addiction module Astex_2946 a09b5299ee65e793ed07f146823c4da8 71 TIGRFAM TIGR02574 stabl_TIGR02574: putative addiction module component, TIGR02574 family 9 68 1.1E-14 T 13-10-2018 IPR013406 Conserved hypothetical protein CHP02574, addiction module Astex_1351 a0ca7e93c9c59e05c706202c44eb0732 195 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 2 22 5.2E-8 T 13-10-2018 Astex_1351 a0ca7e93c9c59e05c706202c44eb0732 195 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 22 41 5.2E-8 T 13-10-2018 Astex_1351 a0ca7e93c9c59e05c706202c44eb0732 195 TIGRFAM TIGR01410 tatB: twin arginine-targeting protein translocase TatB 4 78 2.1E-25 T 13-10-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 Astex_1351 a0ca7e93c9c59e05c706202c44eb0732 195 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 2 190 15.457 T 13-10-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 Astex_1351 a0ca7e93c9c59e05c706202c44eb0732 195 Pfam PF02416 mttA/Hcf106 family 5 35 1.1E-6 T 13-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 Astex_0339 2451e1cb44e8fd37471147e0c2824890 117 Pfam PF11836 Phage tail tube protein, GTA-gp10 5 103 4.1E-25 T 13-10-2018 IPR021791 Phage tail tube protein, GTA-gp10 Astex_2784 60cd5515ecbb5753672bce39b1e09d57 663 Pfam PF00326 Prolyl oligopeptidase family 447 655 7.5E-46 T 13-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 Astex_2784 60cd5515ecbb5753672bce39b1e09d57 663 Gene3D G3DSA:3.40.50.1820 388 657 9.0E-78 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_2784 60cd5515ecbb5753672bce39b1e09d57 663 SUPERFAMILY SSF69304 52 381 9.42E-10 T 13-10-2018 Astex_2784 60cd5515ecbb5753672bce39b1e09d57 663 SUPERFAMILY SSF53474 398 655 2.24E-69 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1741 68a44d4fdadd5bd5c9bd33c27d07d65f 383 PIRSF PIRSF005096 23 382 1.2E-124 T 13-10-2018 IPR015443 Aldose 1-epimerase GO:0016853|GO:0019318 KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 Astex_1741 68a44d4fdadd5bd5c9bd33c27d07d65f 383 SUPERFAMILY SSF74650 28 378 6.91E-111 T 13-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 Astex_1741 68a44d4fdadd5bd5c9bd33c27d07d65f 383 Gene3D G3DSA:2.70.98.10 21 381 3.1E-124 T 13-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 Astex_1741 68a44d4fdadd5bd5c9bd33c27d07d65f 383 Pfam PF01263 Aldose 1-epimerase 43 376 9.8E-94 T 13-10-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 Astex_1969 43bde3983b478e8c42005db2e61da232 224 Gene3D G3DSA:1.10.10.10 125 224 1.3E-31 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1969 43bde3983b478e8c42005db2e61da232 224 Pfam PF00072 Response regulator receiver domain 4 113 1.2E-23 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1969 43bde3983b478e8c42005db2e61da232 224 SUPERFAMILY SSF52172 1 183 1.15E-38 T 13-10-2018 IPR011006 CheY-like superfamily Astex_1969 43bde3983b478e8c42005db2e61da232 224 SMART SM00448 2 113 1.3E-35 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1969 43bde3983b478e8c42005db2e61da232 224 Gene3D G3DSA:3.40.50.2300 1 122 5.4E-34 T 13-10-2018 Astex_1969 43bde3983b478e8c42005db2e61da232 224 SMART SM00862 147 222 3.1E-25 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Astex_1969 43bde3983b478e8c42005db2e61da232 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 222 5.5E-27 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Astex_1481 06795cb8227013c40051da9b37d4d017 150 PIRSF PIRSF018267 1 146 2.1E-52 T 13-10-2018 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 Astex_1481 06795cb8227013c40051da9b37d4d017 150 TIGRFAM TIGR00632 vsr: DNA mismatch endonuclease Vsr 2 118 1.1E-46 T 13-10-2018 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 Astex_1481 06795cb8227013c40051da9b37d4d017 150 SUPERFAMILY SSF52980 2 144 3.91E-54 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 Astex_1481 06795cb8227013c40051da9b37d4d017 150 Pfam PF03852 DNA mismatch endonuclease Vsr 2 74 2.0E-33 T 13-10-2018 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 Astex_1481 06795cb8227013c40051da9b37d4d017 150 Gene3D G3DSA:3.40.960.10 21 150 2.9E-49 T 13-10-2018 Astex_2932 ff6ae321b773feeeb76d1e6a6a3a25bb 195 Pfam PF03981 Ubiquinol-cytochrome C chaperone 44 171 1.9E-20 T 13-10-2018 IPR021150 Ubiquinol-cytochrome c chaperone/UPF0174 Astex_3273 2cca6da50cc240fb0f7528ce1a9ddb9b 557 Pfam PF00563 EAL domain 309 531 1.6E-53 T 13-10-2018 IPR001633 EAL domain Astex_3273 2cca6da50cc240fb0f7528ce1a9ddb9b 557 SUPERFAMILY SSF141868 307 532 2.75E-56 T 13-10-2018 IPR035919 EAL domain superfamily Astex_3273 2cca6da50cc240fb0f7528ce1a9ddb9b 557 SMART SM00052 299 536 4.8E-44 T 13-10-2018 IPR001633 EAL domain Astex_3273 2cca6da50cc240fb0f7528ce1a9ddb9b 557 Gene3D G3DSA:3.20.20.450 301 537 5.1E-61 T 13-10-2018 IPR035919 EAL domain superfamily Astex_3228 d4459c5cb09812f844dffee14c1c2ec8 248 Gene3D G3DSA:2.30.60.10 129 246 6.1E-25 T 13-10-2018 IPR036673 Cyanovirin-N superfamily Astex_3228 d4459c5cb09812f844dffee14c1c2ec8 248 Gene3D G3DSA:2.30.60.10 55 115 8.7E-12 T 13-10-2018 IPR036673 Cyanovirin-N superfamily Astex_3228 d4459c5cb09812f844dffee14c1c2ec8 248 SMART SM01111 57 181 7.4E-17 T 13-10-2018 IPR011058 Cyanovirin-N Astex_3228 d4459c5cb09812f844dffee14c1c2ec8 248 Pfam PF08881 CVNH domain 134 244 5.7E-13 T 13-10-2018 IPR011058 Cyanovirin-N Astex_3228 d4459c5cb09812f844dffee14c1c2ec8 248 SUPERFAMILY SSF51322 56 181 4.53E-16 T 13-10-2018 IPR036673 Cyanovirin-N superfamily Astex_3228 d4459c5cb09812f844dffee14c1c2ec8 248 SUPERFAMILY SSF51322 194 245 6.15E-9 T 13-10-2018 IPR036673 Cyanovirin-N superfamily Astex_3228 d4459c5cb09812f844dffee14c1c2ec8 248 Pfam PF08881 CVNH domain 58 180 4.7E-15 T 13-10-2018 IPR011058 Cyanovirin-N Astex_2913 4964270fcf85043862ae74c0e9735299 518 Gene3D G3DSA:3.30.300.30 416 516 1.9E-9 T 13-10-2018 Astex_2913 4964270fcf85043862ae74c0e9735299 518 Gene3D G3DSA:3.40.50.12780 4 414 3.0E-72 T 13-10-2018 Astex_2913 4964270fcf85043862ae74c0e9735299 518 SUPERFAMILY SSF56801 7 511 1.83E-91 T 13-10-2018 Astex_2913 4964270fcf85043862ae74c0e9735299 518 Pfam PF00501 AMP-binding enzyme 21 419 7.4E-62 T 13-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Astex_3478 c440f7976a89b8c588cc1e21ff9e11bc 336 Gene3D G3DSA:3.40.50.2000 141 315 3.5E-48 T 13-10-2018 Astex_3478 c440f7976a89b8c588cc1e21ff9e11bc 336 Gene3D G3DSA:3.40.50.2000 17 140 3.5E-48 T 13-10-2018 Astex_3478 c440f7976a89b8c588cc1e21ff9e11bc 336 SUPERFAMILY SSF53756 12 331 8.85E-61 T 13-10-2018 Astex_3478 c440f7976a89b8c588cc1e21ff9e11bc 336 Pfam PF00534 Glycosyl transferases group 1 156 304 2.9E-35 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 Astex_2853 90406930cce896863a6c5cd65b672df9 337 Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD 35 102 4.0E-13 T 13-10-2018 IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region GO:0009245|GO:0016747 Astex_2853 90406930cce896863a6c5cd65b672df9 337 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 33 334 1.7E-92 T 13-10-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 Astex_2853 90406930cce896863a6c5cd65b672df9 337 Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. 9 334 29.341 T 13-10-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 Astex_2853 90406930cce896863a6c5cd65b672df9 337 SUPERFAMILY SSF51161 45 324 8.58E-67 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily Astex_2853 90406930cce896863a6c5cd65b672df9 337 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 268 301 8.7E-5 T 13-10-2018 IPR001451 Hexapeptide repeat Astex_2853 90406930cce896863a6c5cd65b672df9 337 Gene3D G3DSA:3.40.1390.10 21 110 5.2E-11 T 13-10-2018 Astex_2853 90406930cce896863a6c5cd65b672df9 337 Gene3D G3DSA:2.160.10.10 113 315 2.7E-58 T 13-10-2018 Astex_2853 90406930cce896863a6c5cd65b672df9 337 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 231 265 7.0E-9 T 13-10-2018 IPR001451 Hexapeptide repeat Astex_2853 90406930cce896863a6c5cd65b672df9 337 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 138 170 9.8E-11 T 13-10-2018 IPR001451 Hexapeptide repeat Astex_2452 be9d537a6496f49df25ad0dfa94e27a8 102 Pfam PF05284 Protein of unknown function (DUF736) 4 99 8.1E-35 T 13-10-2018 IPR007948 Protein of unknown function DUF736 Astex_2209 ae5af200d47c17e2e31ceb624f8a20d3 151 Gene3D G3DSA:3.40.50.2000 12 110 9.4E-7 T 13-10-2018 Astex_2209 ae5af200d47c17e2e31ceb624f8a20d3 151 SUPERFAMILY SSF53756 6 129 4.08E-5 T 13-10-2018 Astex_2209 ae5af200d47c17e2e31ceb624f8a20d3 151 Pfam PF08660 Oligosaccharide biosynthesis protein Alg14 like 53 149 3.2E-10 T 13-10-2018 IPR013969 Oligosaccharide biosynthesis protein Alg14-like GO:0006488 Reactome: R-HSA-446193|Reactome: R-HSA-5633231 Astex_0289 a7c4aef7249d3aa84eed08ad37227a09 243 Pfam PF04116 Fatty acid hydroxylase superfamily 79 209 3.7E-27 T 13-10-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 Astex_2975 e1de560ec696974c1138c1abda20d71d 326 Gene3D G3DSA:1.10.3470.10 1 324 9.3E-80 T 13-10-2018 IPR037294 ABC transporter, BtuC-like Astex_2975 e1de560ec696974c1138c1abda20d71d 326 SUPERFAMILY SSF81345 3 318 1.57E-63 T 13-10-2018 IPR037294 ABC transporter, BtuC-like Astex_2975 e1de560ec696974c1138c1abda20d71d 326 Pfam PF01032 FecCD transport family 11 318 3.4E-72 T 13-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 Astex_2185 2a958cd4171b7827412874ba175708c0 257 Gene3D G3DSA:3.60.21.10 20 257 1.1E-51 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like Astex_2185 2a958cd4171b7827412874ba175708c0 257 Pfam PF00149 Calcineurin-like phosphoesterase 28 218 7.6E-12 T 13-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 Astex_2185 2a958cd4171b7827412874ba175708c0 257 SUPERFAMILY SSF56300 21 241 6.96E-37 T 13-10-2018 Astex_2955 b10840b2eb1094ba18760486a6947eaf 216 Pfam PF12762 ISXO2-like transposase domain 62 199 9.9E-31 T 13-10-2018 IPR024445 ISXO2-like transposase domain Astex_2955 b10840b2eb1094ba18760486a6947eaf 216 SMART SM01126 61 199 6.5E-52 T 13-10-2018 IPR024445 ISXO2-like transposase domain Astex_3470 8c48a57ed0fcea4b1808e11ad34b8f52 159 Gene3D G3DSA:3.90.1680.10 2 138 6.8E-24 T 13-10-2018 IPR036590 SOS response associated peptidase-like Astex_3470 8c48a57ed0fcea4b1808e11ad34b8f52 159 SUPERFAMILY SSF143081 2 122 1.83E-25 T 13-10-2018 IPR036590 SOS response associated peptidase-like Astex_3470 8c48a57ed0fcea4b1808e11ad34b8f52 159 Pfam PF02586 SOS response associated peptidase (SRAP) 1 121 3.1E-18 T 13-10-2018 IPR003738 SOS response associated peptidase (SRAP) Astex_1368 fab433f5d1a53743ef3e1b660b967e36 810 Pfam PF00593 TonB dependent receptor 280 809 5.9E-21 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_1368 fab433f5d1a53743ef3e1b660b967e36 810 Gene3D G3DSA:2.170.130.10 27 173 5.8E-17 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_1368 fab433f5d1a53743ef3e1b660b967e36 810 Gene3D G3DSA:2.40.170.20 181 810 2.4E-55 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_1368 fab433f5d1a53743ef3e1b660b967e36 810 Pfam PF07715 TonB-dependent Receptor Plug Domain 49 162 6.4E-15 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_1368 fab433f5d1a53743ef3e1b660b967e36 810 SUPERFAMILY SSF56935 23 810 4.2E-86 T 13-10-2018 Astex_1158 46f2c39bb251306e48d930d0889f8fc6 177 Pfam PF10722 Putative bacterial sensory transduction regulator 15 153 5.3E-18 T 13-10-2018 IPR019660 Putative sensory transduction regulator YbjN Astex_1844 ac5eabd16e2f1706729110acd2e5c7ff 599 Pfam PF03717 Penicillin-binding Protein dimerisation domain 87 213 6.2E-7 T 13-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 Astex_1844 ac5eabd16e2f1706729110acd2e5c7ff 599 Gene3D G3DSA:3.30.450.330 226 554 1.6E-80 T 13-10-2018 Astex_1844 ac5eabd16e2f1706729110acd2e5c7ff 599 Pfam PF00905 Penicillin binding protein transpeptidase domain 250 551 1.1E-53 T 13-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 Astex_1844 ac5eabd16e2f1706729110acd2e5c7ff 599 SUPERFAMILY SSF56519 87 216 1.57E-19 T 13-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 Astex_1844 ac5eabd16e2f1706729110acd2e5c7ff 599 SUPERFAMILY SSF56601 223 561 2.29E-72 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like Astex_1844 ac5eabd16e2f1706729110acd2e5c7ff 599 Gene3D G3DSA:3.40.710.10 283 464 1.6E-80 T 13-10-2018 Astex_1844 ac5eabd16e2f1706729110acd2e5c7ff 599 Gene3D G3DSA:3.90.1310.30 82 225 5.6E-16 T 13-10-2018 Astex_0679 bfd0f45cd24a931e1eda5a719a4f764e 346 Pfam PF06258 Mitochondrial fission ELM1 30 335 2.9E-95 T 13-10-2018 IPR009367 Mitochondrial fission protein ELM1-like Astex_3256 3512de7d4eb5b52f5be5cad1ea8b278b 480 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 86 480 7.1E-115 T 13-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 Astex_3256 3512de7d4eb5b52f5be5cad1ea8b278b 480 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 95 478 5.0E-151 T 13-10-2018 Astex_3256 3512de7d4eb5b52f5be5cad1ea8b278b 480 Gene3D G3DSA:3.60.70.12 83 351 1.4E-83 T 13-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 Astex_3256 3512de7d4eb5b52f5be5cad1ea8b278b 480 Gene3D G3DSA:3.10.20.340 352 480 2.3E-44 T 13-10-2018 Astex_3256 3512de7d4eb5b52f5be5cad1ea8b278b 480 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 81 480 132.306 T 13-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 Astex_3256 3512de7d4eb5b52f5be5cad1ea8b278b 480 Pfam PF01960 ArgJ family 94 480 2.5E-135 T 13-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 Astex_3256 3512de7d4eb5b52f5be5cad1ea8b278b 480 SUPERFAMILY SSF56266 87 477 5.32E-129 T 13-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 Astex_3663 ee22120bf28f97c088e26066fd12c4a9 447 Gene3D G3DSA:1.20.1600.10 46 446 3.2E-74 T 13-10-2018 Astex_3663 ee22120bf28f97c088e26066fd12c4a9 447 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 10 446 1.0E-62 T 13-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 Astex_3663 ee22120bf28f97c088e26066fd12c4a9 447 Pfam PF02321 Outer membrane efflux protein 56 210 3.3E-17 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Astex_3663 ee22120bf28f97c088e26066fd12c4a9 447 Pfam PF02321 Outer membrane efflux protein 272 444 3.5E-21 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Astex_3663 ee22120bf28f97c088e26066fd12c4a9 447 SUPERFAMILY SSF56954 2 446 4.32E-68 T 13-10-2018 Astex_3663 ee22120bf28f97c088e26066fd12c4a9 447 Gene3D G3DSA:2.20.200.10 91 333 3.2E-74 T 13-10-2018 Astex_2606 8d1a4b43c0dc906c395bdc0d7fd03dd9 642 Gene3D G3DSA:2.30.42.10 549 618 4.3E-8 T 13-10-2018 Astex_2606 8d1a4b43c0dc906c395bdc0d7fd03dd9 642 Gene3D G3DSA:2.60.40.3650 45 221 2.4E-12 T 13-10-2018 Astex_2606 8d1a4b43c0dc906c395bdc0d7fd03dd9 642 Pfam PF05299 M61 glycyl aminopeptidase 317 432 6.3E-33 T 13-10-2018 IPR007963 Peptidase M61, catalytic domain Astex_2606 8d1a4b43c0dc906c395bdc0d7fd03dd9 642 Gene3D G3DSA:1.10.390.60 233 499 1.0E-60 T 13-10-2018 Astex_2606 8d1a4b43c0dc906c395bdc0d7fd03dd9 642 SUPERFAMILY SSF50156 538 614 4.21E-9 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 Astex_2606 8d1a4b43c0dc906c395bdc0d7fd03dd9 642 PIRSF PIRSF016493 41 642 4.9E-125 T 13-10-2018 IPR024191 Peptidase M61 Astex_3332 25e0c9f29c1294da95d55a3eac19c0f3 265 PIRSF PIRSF002854 2 265 4.2E-100 T 13-10-2018 IPR004872 Lipoprotein NlpA family Astex_3332 25e0c9f29c1294da95d55a3eac19c0f3 265 Gene3D G3DSA:3.40.190.10 30 262 6.6E-96 T 13-10-2018 Astex_3332 25e0c9f29c1294da95d55a3eac19c0f3 265 SUPERFAMILY SSF53850 31 265 1.52E-78 T 13-10-2018 Astex_3332 25e0c9f29c1294da95d55a3eac19c0f3 265 Pfam PF03180 NLPA lipoprotein 30 265 3.5E-93 T 13-10-2018 IPR004872 Lipoprotein NlpA family Astex_3332 25e0c9f29c1294da95d55a3eac19c0f3 265 Gene3D G3DSA:3.40.190.10 111 215 6.6E-96 T 13-10-2018 Astex_3334 eb2c6753fcca6532c5002080ffa29f04 339 Pfam PF00005 ABC transporter 31 180 1.6E-34 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_3334 eb2c6753fcca6532c5002080ffa29f04 339 Gene3D G3DSA:3.30.70.260 263 338 2.8E-5 T 13-10-2018 Astex_3334 eb2c6753fcca6532c5002080ffa29f04 339 SMART SM00382 40 229 1.1E-18 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_3334 eb2c6753fcca6532c5002080ffa29f04 339 SUPERFAMILY SSF52540 12 246 3.99E-77 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_3334 eb2c6753fcca6532c5002080ffa29f04 339 SUPERFAMILY SSF55021 267 336 5.26E-9 T 13-10-2018 Astex_3334 eb2c6753fcca6532c5002080ffa29f04 339 Gene3D G3DSA:3.40.50.300 9 262 2.9E-79 T 13-10-2018 Astex_3334 eb2c6753fcca6532c5002080ffa29f04 339 Pfam PF09383 NIL domain 268 335 5.2E-11 T 13-10-2018 IPR018449 NIL domain Astex_3334 eb2c6753fcca6532c5002080ffa29f04 339 SMART SM00930 264 337 5.5E-9 T 13-10-2018 IPR018449 NIL domain Astex_3334 eb2c6753fcca6532c5002080ffa29f04 339 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Astex_2382 0cd3473ddeb7d4a3b7a42ea527a730c7 246 Gene3D G3DSA:3.40.50.300 50 164 1.4E-15 T 13-10-2018 Astex_2382 0cd3473ddeb7d4a3b7a42ea527a730c7 246 PIRSF PIRSF034285 1 245 5.5E-67 T 13-10-2018 IPR017026 Inducible mutagenesis protein A Astex_2382 0cd3473ddeb7d4a3b7a42ea527a730c7 246 SUPERFAMILY SSF52540 49 165 1.27E-22 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1263 cdae2a297f49f834e79f4d7d82fa55de 230 Gene3D G3DSA:3.40.50.1820 3 221 1.3E-16 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1263 cdae2a297f49f834e79f4d7d82fa55de 230 SUPERFAMILY SSF53474 3 219 3.08E-19 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1263 cdae2a297f49f834e79f4d7d82fa55de 230 Pfam PF12697 Alpha/beta hydrolase family 6 186 4.6E-7 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Astex_2974 2e44f82e86c5628a6b8cd874ef1466f1 259 SMART SM00382 26 206 8.8E-18 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_2974 2e44f82e86c5628a6b8cd874ef1466f1 259 Gene3D G3DSA:3.40.50.300 1 233 1.5E-65 T 13-10-2018 Astex_2974 2e44f82e86c5628a6b8cd874ef1466f1 259 Pfam PF00005 ABC transporter 18 157 3.4E-33 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_2974 2e44f82e86c5628a6b8cd874ef1466f1 259 SUPERFAMILY SSF52540 2 218 8.5E-60 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2974 2e44f82e86c5628a6b8cd874ef1466f1 259 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Astex_2632 2c9f693d4e45a03736df68502baae0f0 137 Pfam PF03061 Thioesterase superfamily 53 121 8.0E-7 T 13-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 Astex_2632 2c9f693d4e45a03736df68502baae0f0 137 SUPERFAMILY SSF54637 10 136 1.38E-17 T 13-10-2018 IPR029069 HotDog domain superfamily Astex_2632 2c9f693d4e45a03736df68502baae0f0 137 Gene3D G3DSA:3.10.129.10 6 137 6.6E-44 T 13-10-2018 Astex_1938 4e6ae2653cf35c4cd830954043db3757 610 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 6 26 1.4E-6 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Astex_1938 4e6ae2653cf35c4cd830954043db3757 610 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 27 45 1.4E-6 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Astex_1938 4e6ae2653cf35c4cd830954043db3757 610 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 55 70 1.4E-6 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 Astex_1938 4e6ae2653cf35c4cd830954043db3757 610 SUPERFAMILY SSF52540 6 178 2.37E-34 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1938 4e6ae2653cf35c4cd830954043db3757 610 Pfam PF02421 Ferrous iron transport protein B 6 165 4.5E-54 T 13-10-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 Astex_1938 4e6ae2653cf35c4cd830954043db3757 610 Gene3D G3DSA:3.40.50.300 5 199 9.3E-40 T 13-10-2018 Astex_1938 4e6ae2653cf35c4cd830954043db3757 610 Pfam PF07664 Ferrous iron transport protein B C terminus 391 443 4.3E-16 T 13-10-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 Astex_1938 4e6ae2653cf35c4cd830954043db3757 610 Pfam PF07670 Nucleoside recognition 279 368 1.2E-10 T 13-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 Astex_1938 4e6ae2653cf35c4cd830954043db3757 610 Pfam PF07670 Nucleoside recognition 449 580 1.1E-23 T 13-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 Astex_1840 406330ae5dedf5f9385c21dc1d7ed245 488 SUPERFAMILY SSF53623 135 340 1.7E-50 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Astex_1840 406330ae5dedf5f9385c21dc1d7ed245 488 SUPERFAMILY SSF51984 26 118 2.9E-14 T 13-10-2018 Astex_1840 406330ae5dedf5f9385c21dc1d7ed245 488 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 30 481 32.363 T 13-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 Astex_1840 406330ae5dedf5f9385c21dc1d7ed245 488 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 139 162 - T 13-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 Astex_1840 406330ae5dedf5f9385c21dc1d7ed245 488 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 31 478 2.0E-115 T 13-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 Astex_1840 406330ae5dedf5f9385c21dc1d7ed245 488 Pfam PF08245 Mur ligase middle domain 141 322 1.8E-32 T 13-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Astex_1840 406330ae5dedf5f9385c21dc1d7ed245 488 Gene3D G3DSA:3.40.50.720 26 117 3.8E-17 T 13-10-2018 Astex_1840 406330ae5dedf5f9385c21dc1d7ed245 488 Gene3D G3DSA:3.90.190.20 348 484 3.5E-36 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Astex_1840 406330ae5dedf5f9385c21dc1d7ed245 488 SUPERFAMILY SSF53244 342 480 3.85E-34 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 Astex_1840 406330ae5dedf5f9385c21dc1d7ed245 488 Gene3D G3DSA:3.40.1190.10 118 342 1.2E-56 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 Astex_1421 8172789130bab9269ff66a2227f3806e 137 Pfam PF00460 Flagella basal body rod protein 21 39 1.8E-4 T 13-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 Astex_1421 8172789130bab9269ff66a2227f3806e 137 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 10 129 7.0E-21 T 13-10-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 Astex_1421 8172789130bab9269ff66a2227f3806e 137 PIRSF PIRSF002889 1 134 1.3E-21 T 13-10-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 Astex_0413 15079ba43df4456889bb968f97f1cc18 270 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 66 236 5.4E-41 T 13-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 Astex_0413 15079ba43df4456889bb968f97f1cc18 270 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 65 238 3.7E-29 T 13-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 Astex_3745 0bb1af89dfd3f4c01912bc4f9d170508 94 Pfam PF01527 Transposase 4 75 3.6E-9 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 Astex_3745 0bb1af89dfd3f4c01912bc4f9d170508 94 SUPERFAMILY SSF48295 2 60 6.28E-15 T 13-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 Astex_0276 9b84e47c0d8598615a35803f471af77a 271 Pfam PF00005 ABC transporter 30 190 2.7E-30 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_0276 9b84e47c0d8598615a35803f471af77a 271 Gene3D G3DSA:3.40.50.300 2 265 1.7E-61 T 13-10-2018 Astex_0276 9b84e47c0d8598615a35803f471af77a 271 SUPERFAMILY SSF52540 6 251 2.55E-57 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0276 9b84e47c0d8598615a35803f471af77a 271 SMART SM00382 39 247 2.8E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_2423 9c3eb1864160b60638fd3f9a48ea035e 158 SUPERFAMILY SSF54427 20 140 9.33E-18 T 13-10-2018 IPR032710 NTF2-like domain superfamily Astex_2423 9c3eb1864160b60638fd3f9a48ea035e 158 Gene3D G3DSA:3.10.450.50 20 141 1.7E-12 T 13-10-2018 Astex_2423 9c3eb1864160b60638fd3f9a48ea035e 158 Pfam PF14534 Domain of unknown function (DUF4440) 27 136 7.3E-17 T 13-10-2018 IPR027843 Domain of unknown function DUF4440 Astex_1198 707b2ae7fe73e2c0447f26134c7ea116 275 Gene3D G3DSA:3.60.10.10 17 275 1.5E-79 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily Astex_1198 707b2ae7fe73e2c0447f26134c7ea116 275 SUPERFAMILY SSF56219 21 274 2.62E-35 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily Astex_1198 707b2ae7fe73e2c0447f26134c7ea116 275 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 25 265 1.0E-9 T 13-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase Astex_1072 6db6f3223ac96423025fb13a473aa350 170 SUPERFAMILY SSF55729 1 160 1.24E-25 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Astex_1072 6db6f3223ac96423025fb13a473aa350 170 Gene3D G3DSA:3.40.630.30 2 170 1.4E-32 T 13-10-2018 Astex_1072 6db6f3223ac96423025fb13a473aa350 170 Pfam PF13508 Acetyltransferase (GNAT) domain 67 149 6.9E-10 T 13-10-2018 IPR000182 GNAT domain Astex_3060 2a326f109d4ef395b292bcdb51a00cbb 309 Pfam PF00174 Oxidoreductase molybdopterin binding domain 94 247 4.0E-28 T 13-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 Astex_3060 2a326f109d4ef395b292bcdb51a00cbb 309 SUPERFAMILY SSF56524 57 305 4.71E-87 T 13-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 Astex_3060 2a326f109d4ef395b292bcdb51a00cbb 309 Gene3D G3DSA:3.90.420.10 50 309 4.8E-103 T 13-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 Astex_3060 2a326f109d4ef395b292bcdb51a00cbb 309 Hamap MF_01206 Protein-methionine-sulfoxide reductase catalytic subunit MsrP [msrP]. 7 309 54.189 T 13-10-2018 IPR022867 Protein-methionine-sulfoxide reductase subunit MsrP GO:0016667|GO:0030091|GO:0043546|GO:0055114 Astex_2007 4c5c339bce640a05fd29a80471f6effd 527 Pfam PF00474 Sodium:solute symporter family 39 432 1.1E-56 T 13-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 Astex_2007 4c5c339bce640a05fd29a80471f6effd 527 Gene3D G3DSA:1.20.1730.10 14 517 8.9E-103 T 13-10-2018 IPR038377 Sodium/glucose symporter superfamily Astex_2007 4c5c339bce640a05fd29a80471f6effd 527 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 39 432 1.1E-75 T 13-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 Astex_3107 808cea7edcf54d69b283964e236099db 109 Pfam PF03646 FlaG protein 57 105 2.8E-6 T 13-10-2018 IPR005186 FlaG protein Astex_3107 808cea7edcf54d69b283964e236099db 109 SUPERFAMILY SSF160214 51 107 7.85E-11 T 13-10-2018 IPR035924 FlaG-like superfamily Astex_2173 77960c7532fa8a170914d488f7f7326c 1107 Pfam PF00176 SNF2 family N-terminal domain 661 930 2.5E-64 T 13-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 Astex_2173 77960c7532fa8a170914d488f7f7326c 1107 SMART SM00490 972 1052 4.6E-22 T 13-10-2018 IPR001650 Helicase, C-terminal Astex_2173 77960c7532fa8a170914d488f7f7326c 1107 Pfam PF04434 SWIM zinc finger 70 92 1.0E-4 T 13-10-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 Astex_2173 77960c7532fa8a170914d488f7f7326c 1107 Gene3D G3DSA:3.40.50.10810 648 859 2.8E-68 T 13-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily Astex_2173 77960c7532fa8a170914d488f7f7326c 1107 SUPERFAMILY SSF52540 859 1106 1.09E-62 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2173 77960c7532fa8a170914d488f7f7326c 1107 SUPERFAMILY SSF52540 614 858 6.69E-60 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2173 77960c7532fa8a170914d488f7f7326c 1107 Gene3D G3DSA:1.20.120.850 880 1101 8.9E-78 T 13-10-2018 Astex_2173 77960c7532fa8a170914d488f7f7326c 1107 Gene3D G3DSA:3.40.50.300 865 1066 8.9E-78 T 13-10-2018 Astex_2173 77960c7532fa8a170914d488f7f7326c 1107 SMART SM00487 643 832 7.5E-32 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain Astex_2173 77960c7532fa8a170914d488f7f7326c 1107 Pfam PF00271 Helicase conserved C-terminal domain 943 1052 1.2E-16 T 13-10-2018 IPR001650 Helicase, C-terminal Astex_3196 a8d28d246ff206d41908ede6afcde98d 184 SUPERFAMILY SSF52218 4 176 4.03E-48 T 13-10-2018 IPR029039 Flavoprotein-like superfamily Astex_3196 a8d28d246ff206d41908ede6afcde98d 184 Gene3D G3DSA:3.40.50.360 2 183 5.2E-50 T 13-10-2018 IPR029039 Flavoprotein-like superfamily Astex_3196 a8d28d246ff206d41908ede6afcde98d 184 Pfam PF03358 NADPH-dependent FMN reductase 5 149 1.7E-36 T 13-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 Astex_2385 93641b577f7e13af975a716d76a49657 506 Pfam PF00817 impB/mucB/samB family 29 148 1.8E-7 T 13-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 Astex_2385 93641b577f7e13af975a716d76a49657 506 Gene3D G3DSA:3.30.70.270 77 176 3.7E-7 T 13-10-2018 Astex_2385 93641b577f7e13af975a716d76a49657 506 SUPERFAMILY SSF56672 28 235 3.11E-34 T 13-10-2018 Astex_2385 93641b577f7e13af975a716d76a49657 506 Gene3D G3DSA:2.30.40.20 38 76 3.7E-7 T 13-10-2018 Astex_2385 93641b577f7e13af975a716d76a49657 506 Gene3D G3DSA:1.10.150.20 177 220 3.7E-7 T 13-10-2018 Astex_3097 8254e158d8deec8d3e1523a8115ba8e2 74 Pfam PF13488 Glycine zipper 21 61 1.7E-6 T 13-10-2018 IPR039567 Glycine zipper domain Astex_3277 2a7cea14441c610393227087922fdcdc 436 SUPERFAMILY SSF53300 228 364 4.78E-8 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Astex_3277 2a7cea14441c610393227087922fdcdc 436 Pfam PF01882 Protein of unknown function DUF58 191 275 4.3E-15 T 13-10-2018 IPR002881 Domain of unknown function DUF58 Astex_1907 c773cee67f49cb03c56ed1a72f470f82 287 Pfam PF01263 Aldose 1-epimerase 6 277 3.4E-36 T 13-10-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 Astex_1907 c773cee67f49cb03c56ed1a72f470f82 287 Gene3D G3DSA:2.70.98.10 4 285 8.5E-65 T 13-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 Astex_1907 c773cee67f49cb03c56ed1a72f470f82 287 SUPERFAMILY SSF74650 5 282 2.95E-45 T 13-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 Astex_0653 3d9380bddc8b674c568a5428cc664174 117 Pfam PF02627 Carboxymuconolactone decarboxylase family 24 105 3.4E-21 T 13-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 Astex_0653 3d9380bddc8b674c568a5428cc664174 117 Gene3D G3DSA:1.20.1290.10 1 114 1.8E-35 T 13-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 Astex_0653 3d9380bddc8b674c568a5428cc664174 117 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 41 89 8.5E-14 T 13-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 Astex_0653 3d9380bddc8b674c568a5428cc664174 117 SUPERFAMILY SSF69118 4 109 1.3E-29 T 13-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 Astex_3664 2679b501c132a2efc55b86e78a94cb88 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 125 133 4.3E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_3664 2679b501c132a2efc55b86e78a94cb88 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 4.3E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_3664 2679b501c132a2efc55b86e78a94cb88 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 164 4.3E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_3664 2679b501c132a2efc55b86e78a94cb88 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 8.5E-26 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_3664 2679b501c132a2efc55b86e78a94cb88 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 8.5E-26 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_3664 2679b501c132a2efc55b86e78a94cb88 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 8.5E-26 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_3664 2679b501c132a2efc55b86e78a94cb88 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 8.5E-26 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_3664 2679b501c132a2efc55b86e78a94cb88 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 8.5E-26 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_3664 2679b501c132a2efc55b86e78a94cb88 269 SUPERFAMILY SSF51735 2 216 1.07E-61 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_3664 2679b501c132a2efc55b86e78a94cb88 269 Pfam PF00106 short chain dehydrogenase 5 186 2.4E-50 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_3664 2679b501c132a2efc55b86e78a94cb88 269 Gene3D G3DSA:3.40.50.720 4 245 2.5E-65 T 13-10-2018 Astex_1992 331c7fe40466ddb1eea9cbe20f4d6c77 161 ProSitePatterns PS01117 MarR-type HTH domain signature. 77 111 - T 13-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site Astex_1992 331c7fe40466ddb1eea9cbe20f4d6c77 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 98 114 2.3E-12 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Astex_1992 331c7fe40466ddb1eea9cbe20f4d6c77 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 62 78 2.3E-12 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Astex_1992 331c7fe40466ddb1eea9cbe20f4d6c77 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 79 94 2.3E-12 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Astex_1992 331c7fe40466ddb1eea9cbe20f4d6c77 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 128 148 2.3E-12 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Astex_1992 331c7fe40466ddb1eea9cbe20f4d6c77 161 Gene3D G3DSA:1.10.10.10 2 154 6.0E-32 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1992 331c7fe40466ddb1eea9cbe20f4d6c77 161 Pfam PF12802 MarR family 44 101 4.2E-14 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Astex_1992 331c7fe40466ddb1eea9cbe20f4d6c77 161 SUPERFAMILY SSF46785 17 155 1.43E-32 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_1992 331c7fe40466ddb1eea9cbe20f4d6c77 161 SMART SM00347 38 138 5.7E-16 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 Astex_1686 b426b235f07d4fd49857415feb5c6520 192 Gene3D G3DSA:3.30.420.10 8 167 2.8E-42 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Astex_1686 b426b235f07d4fd49857415feb5c6520 192 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 8 159 8.5E-39 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 Astex_1686 b426b235f07d4fd49857415feb5c6520 192 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 9 22 3.2E-20 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 Astex_1686 b426b235f07d4fd49857415feb5c6520 192 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 66 82 3.2E-20 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 Astex_1686 b426b235f07d4fd49857415feb5c6520 192 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 88 104 3.2E-20 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 Astex_1686 b426b235f07d4fd49857415feb5c6520 192 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 112 131 3.2E-20 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 Astex_1686 b426b235f07d4fd49857415feb5c6520 192 SUPERFAMILY SSF53098 7 164 7.91E-44 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily Astex_1686 b426b235f07d4fd49857415feb5c6520 192 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 8 167 2.2E-38 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 Astex_1686 b426b235f07d4fd49857415feb5c6520 192 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 6 162 41.649 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 Astex_0896 7d1fd43a967e4cea38fccda6d47bb6cb 485 SUPERFAMILY SSF51261 151 399 1.15E-68 T 13-10-2018 IPR011055 Duplicated hybrid motif Astex_0896 7d1fd43a967e4cea38fccda6d47bb6cb 485 Pfam PF01551 Peptidase family M23 304 398 5.7E-36 T 13-10-2018 IPR016047 Peptidase M23 Astex_0896 7d1fd43a967e4cea38fccda6d47bb6cb 485 Gene3D G3DSA:3.10.450.350 178 419 7.9E-77 T 13-10-2018 Astex_0896 7d1fd43a967e4cea38fccda6d47bb6cb 485 Gene3D G3DSA:2.70.70.10 275 404 7.9E-77 T 13-10-2018 IPR011055 Duplicated hybrid motif Astex_1858 a02109f8ae54840a1b3d8b364e26b6e7 416 Gene3D G3DSA:3.90.230.10 186 416 3.5E-64 T 13-10-2018 Astex_1858 a02109f8ae54840a1b3d8b364e26b6e7 416 Pfam PF00557 Metallopeptidase family M24 194 398 9.9E-48 T 13-10-2018 IPR000994 Peptidase M24 Astex_1858 a02109f8ae54840a1b3d8b364e26b6e7 416 SUPERFAMILY SSF55920 188 410 1.7E-59 T 13-10-2018 IPR036005 Creatinase/aminopeptidase-like Astex_1858 a02109f8ae54840a1b3d8b364e26b6e7 416 SUPERFAMILY SSF53092 33 168 1.22E-20 T 13-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal Astex_1858 a02109f8ae54840a1b3d8b364e26b6e7 416 Pfam PF01321 Creatinase/Prolidase N-terminal domain 53 186 2.2E-18 T 13-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 Astex_1858 a02109f8ae54840a1b3d8b364e26b6e7 416 Gene3D G3DSA:3.40.350.10 19 184 3.5E-43 T 13-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal Astex_3721 7d820b947f62b9793490ea5ff9f8675a 264 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 24 101 1.5E-18 T 13-10-2018 IPR010627 Peptidase A24A, N-terminal Astex_3721 7d820b947f62b9793490ea5ff9f8675a 264 Pfam PF01478 Type IV leader peptidase family 118 220 2.7E-9 T 13-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 Astex_0150 4e4cc4ab4517aa91bc2fa97bb6771d5d 281 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 9 275 27.086 T 13-10-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 Astex_0150 4e4cc4ab4517aa91bc2fa97bb6771d5d 281 SUPERFAMILY SSF51735 111 267 1.08E-28 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_0150 4e4cc4ab4517aa91bc2fa97bb6771d5d 281 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 128 201 4.0E-11 T 13-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase Astex_0150 4e4cc4ab4517aa91bc2fa97bb6771d5d 281 Gene3D G3DSA:3.40.50.10860 13 263 4.9E-63 T 13-10-2018 Astex_0150 4e4cc4ab4517aa91bc2fa97bb6771d5d 281 Gene3D G3DSA:3.40.50.720 110 242 4.9E-63 T 13-10-2018 Astex_0150 4e4cc4ab4517aa91bc2fa97bb6771d5d 281 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 14 96 2.4E-21 T 13-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 Astex_0150 4e4cc4ab4517aa91bc2fa97bb6771d5d 281 SUPERFAMILY SSF53223 6 110 5.07E-23 T 13-10-2018 Astex_3233 efcbdb252e75621479342fceb47b21f5 115 Pfam PF05717 IS66 Orf2 like protein 9 105 1.4E-36 T 13-10-2018 IPR008878 Transposase IS66, Orf2 Astex_0252 efcbdb252e75621479342fceb47b21f5 115 Pfam PF05717 IS66 Orf2 like protein 9 105 1.4E-36 T 13-10-2018 IPR008878 Transposase IS66, Orf2 Astex_3835 ceb78e9bc0aca3d1b8f3549885841410 146 Pfam PF13801 Heavy-metal resistance 11 129 7.8E-18 T 13-10-2018 IPR025961 Heavy-metal resistance protein Astex_3835 ceb78e9bc0aca3d1b8f3549885841410 146 Gene3D G3DSA:1.20.120.1490 31 146 2.0E-33 T 13-10-2018 Astex_1098 592775d7b0bf5ce540e5013c0b26e129 140 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 3 115 3.5E-36 T 13-10-2018 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 Astex_1098 592775d7b0bf5ce540e5013c0b26e129 140 Pfam PF03960 ArsC family 6 113 1.2E-12 T 13-10-2018 IPR006660 Arsenate reductase-like Astex_1098 592775d7b0bf5ce540e5013c0b26e129 140 Gene3D G3DSA:3.40.30.10 1 140 4.3E-49 T 13-10-2018 Astex_1098 592775d7b0bf5ce540e5013c0b26e129 140 SUPERFAMILY SSF52833 2 137 3.58E-33 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Astex_0146 abce4eff20117bb89faad6c60c6ffa63 341 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 7 340 2.4E-97 T 13-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 Astex_0146 abce4eff20117bb89faad6c60c6ffa63 341 Gene3D G3DSA:3.20.20.210 3 341 7.4E-102 T 13-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 Astex_0146 abce4eff20117bb89faad6c60c6ffa63 341 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 8 340 1.0E-104 T 13-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 Astex_0146 abce4eff20117bb89faad6c60c6ffa63 341 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 21 30 - T 13-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 Astex_0146 abce4eff20117bb89faad6c60c6ffa63 341 SUPERFAMILY SSF51726 7 338 2.44E-80 T 13-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 Astex_0490 91aa2034f2655a0808b10447e57b1a8f 277 Pfam PF01817 Chorismate mutase type II 20 100 1.4E-15 T 13-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 Astex_0490 91aa2034f2655a0808b10447e57b1a8f 277 SUPERFAMILY SSF48600 15 101 8.55E-14 T 13-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 Astex_0490 91aa2034f2655a0808b10447e57b1a8f 277 SMART SM00830 20 103 1.4E-16 T 13-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 Astex_0490 91aa2034f2655a0808b10447e57b1a8f 277 Gene3D G3DSA:1.20.59.10 14 104 4.2E-16 T 13-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 Astex_0803 f6f3f8ff27d344b8453431ebbdf3fe0a 328 Gene3D G3DSA:1.20.1530.20 8 325 3.5E-26 T 13-10-2018 IPR038770 Sodium/solute symporter superfamily Astex_0803 f6f3f8ff27d344b8453431ebbdf3fe0a 328 Pfam PF13593 SBF-like CPA transporter family (DUF4137) 18 324 4.7E-94 T 13-10-2018 IPR016833 Putative sodium bile acid cotransporter Astex_0803 f6f3f8ff27d344b8453431ebbdf3fe0a 328 PIRSF PIRSF026166 8 328 9.9E-115 T 13-10-2018 IPR016833 Putative sodium bile acid cotransporter Astex_0856 077fec4c5d8ee4eceee69cfc48118bee 368 Pfam PF01757 Acyltransferase family 18 344 6.4E-21 T 13-10-2018 IPR002656 Acyltransferase 3 GO:0016747 Astex_2336 a7f37b170a5c050483c5fb4afca3ea71 365 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 22 314 1.5E-22 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Astex_2336 a7f37b170a5c050483c5fb4afca3ea71 365 Hamap MF_01685 Ferredoxin--NADP reductase. 20 355 39.91 T 13-10-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 Astex_2336 a7f37b170a5c050483c5fb4afca3ea71 365 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 130 148 9.1E-12 T 13-10-2018 Astex_2336 a7f37b170a5c050483c5fb4afca3ea71 365 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 178 196 9.1E-12 T 13-10-2018 Astex_2336 a7f37b170a5c050483c5fb4afca3ea71 365 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 292 314 9.1E-12 T 13-10-2018 Astex_2336 a7f37b170a5c050483c5fb4afca3ea71 365 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 23 42 9.1E-12 T 13-10-2018 Astex_2336 a7f37b170a5c050483c5fb4afca3ea71 365 SUPERFAMILY SSF51905 22 340 1.87E-39 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_2336 a7f37b170a5c050483c5fb4afca3ea71 365 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 79 89 3.1E-18 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Astex_2336 a7f37b170a5c050483c5fb4afca3ea71 365 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 174 198 3.1E-18 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Astex_2336 a7f37b170a5c050483c5fb4afca3ea71 365 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 22 44 3.1E-18 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Astex_2336 a7f37b170a5c050483c5fb4afca3ea71 365 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 302 320 3.1E-18 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Astex_2336 a7f37b170a5c050483c5fb4afca3ea71 365 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 131 139 3.1E-18 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 Astex_2336 a7f37b170a5c050483c5fb4afca3ea71 365 Gene3D G3DSA:3.50.50.60 146 272 5.0E-89 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_2336 a7f37b170a5c050483c5fb4afca3ea71 365 Gene3D G3DSA:3.50.50.60 22 334 5.0E-89 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_2404 d7ff4e9e0536ae4a9a9bdc2263ef2461 420 Pfam PF07746 Aromatic-ring-opening dioxygenase LigAB, LigA subunit 323 409 3.1E-33 T 13-10-2018 IPR011986 Extradiol ring-cleavage dioxygenase LigAB, LigA subunit Astex_2404 d7ff4e9e0536ae4a9a9bdc2263ef2461 420 Gene3D G3DSA:1.10.700.10 308 420 1.9E-45 T 13-10-2018 IPR036622 Dioxygenase LigAB, LigA subunit superfamily Astex_2404 d7ff4e9e0536ae4a9a9bdc2263ef2461 420 SUPERFAMILY SSF53213 2 281 3.79E-91 T 13-10-2018 Astex_2404 d7ff4e9e0536ae4a9a9bdc2263ef2461 420 Gene3D G3DSA:3.40.830.10 3 307 1.3E-92 T 13-10-2018 Astex_2404 d7ff4e9e0536ae4a9a9bdc2263ef2461 420 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 7 273 1.1E-64 T 13-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 Astex_2404 d7ff4e9e0536ae4a9a9bdc2263ef2461 420 SUPERFAMILY SSF48076 295 418 4.05E-44 T 13-10-2018 IPR036622 Dioxygenase LigAB, LigA subunit superfamily Astex_2473 d6dae1407ad1dd30e1267f386cdbb0d4 802 Pfam PF07715 TonB-dependent Receptor Plug Domain 69 164 5.6E-10 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_2473 d6dae1407ad1dd30e1267f386cdbb0d4 802 SUPERFAMILY SSF56935 27 802 1.1E-65 T 13-10-2018 Astex_2473 d6dae1407ad1dd30e1267f386cdbb0d4 802 Gene3D G3DSA:2.170.130.10 52 175 8.6E-17 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_0198 880d07947e69f149c81f56e3101160bf 123 Pfam PF01042 Endoribonuclease L-PSP 14 122 5.6E-21 T 13-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 Astex_0198 880d07947e69f149c81f56e3101160bf 123 SUPERFAMILY SSF55298 12 123 1.73E-27 T 13-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 Astex_0198 880d07947e69f149c81f56e3101160bf 123 Gene3D G3DSA:3.30.1330.40 5 123 1.7E-28 T 13-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 Astex_3744 ffb3d6a4451adf4d4a93f4f4f2d9d6df 406 ProSitePatterns PS01007 Transposases, Mutator family, signature. 234 258 - T 13-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 Astex_3744 ffb3d6a4451adf4d4a93f4f4f2d9d6df 406 Pfam PF00872 Transposase, Mutator family 14 380 3.5E-129 T 13-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 Astex_1379 280154db5a38ac80ac519278ba73a718 727 SUPERFAMILY SSF110296 35 398 1.57E-55 T 13-10-2018 Astex_1379 280154db5a38ac80ac519278ba73a718 727 SUPERFAMILY SSF110296 455 723 4.19E-29 T 13-10-2018 Astex_1379 280154db5a38ac80ac519278ba73a718 727 Gene3D G3DSA:2.130.10.10 35 723 3.7E-208 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 Astex_1379 280154db5a38ac80ac519278ba73a718 727 Gene3D G3DSA:2.130.10.10 45 415 3.7E-208 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 Astex_0193 6b9590236ffdd7d9b6f6e4b06e394222 785 SUPERFAMILY SSF56935 27 784 3.33E-99 T 13-10-2018 Astex_0193 6b9590236ffdd7d9b6f6e4b06e394222 785 Pfam PF00593 TonB dependent receptor 305 784 1.2E-34 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_0193 6b9590236ffdd7d9b6f6e4b06e394222 785 Pfam PF07715 TonB-dependent Receptor Plug Domain 50 157 1.7E-14 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_2261 16430a587e1b1b660f9a5cc51b96ad2f 180 SUPERFAMILY SSF51182 1 178 1.68E-71 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily Astex_2261 16430a587e1b1b660f9a5cc51b96ad2f 180 Gene3D G3DSA:2.60.120.10 1 180 2.4E-69 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Astex_2261 16430a587e1b1b660f9a5cc51b96ad2f 180 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 7 177 9.5E-68 T 13-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 Astex_2261 16430a587e1b1b660f9a5cc51b96ad2f 180 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 179 4.0E-61 T 13-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 Astex_2261 16430a587e1b1b660f9a5cc51b96ad2f 180 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 4 177 6.3E-66 T 13-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 Astex_0909 a003dfcacd3c1def3f456ab2eda789ce 416 Gene3D G3DSA:1.10.260.40 44 139 2.0E-24 T 13-10-2018 Astex_0909 a003dfcacd3c1def3f456ab2eda789ce 416 SMART SM00530 57 118 8.0E-6 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Astex_0909 a003dfcacd3c1def3f456ab2eda789ce 416 SUPERFAMILY SSF47413 51 119 2.22E-6 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Astex_0909 a003dfcacd3c1def3f456ab2eda789ce 416 Pfam PF13413 Helix-turn-helix domain 58 117 2.4E-19 T 13-10-2018 Astex_0934 4d2aaa7c046d0b946ee9ab190879455e 463 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 263 300 - T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Astex_0934 4d2aaa7c046d0b946ee9ab190879455e 463 SUPERFAMILY SSF53383 38 455 1.6E-120 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Astex_0934 4d2aaa7c046d0b946ee9ab190879455e 463 Pfam PF00202 Aminotransferase class-III 39 451 3.2E-91 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Astex_0934 4d2aaa7c046d0b946ee9ab190879455e 463 Gene3D G3DSA:3.40.640.10 72 349 1.2E-169 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Astex_0934 4d2aaa7c046d0b946ee9ab190879455e 463 PIRSF PIRSF000521 144 456 1.0E-21 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Astex_0934 4d2aaa7c046d0b946ee9ab190879455e 463 PIRSF PIRSF000521 40 155 1.1E-6 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Astex_0934 4d2aaa7c046d0b946ee9ab190879455e 463 Gene3D G3DSA:3.90.1150.10 19 453 1.2E-169 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Astex_2907 6cefc65487743487c3e414a476375055 241 SMART SM00382 31 226 7.0E-4 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_2907 6cefc65487743487c3e414a476375055 241 Pfam PF00005 ABC transporter 23 162 2.1E-22 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_2907 6cefc65487743487c3e414a476375055 241 SUPERFAMILY SSF52540 3 222 4.99E-45 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2907 6cefc65487743487c3e414a476375055 241 Gene3D G3DSA:3.40.50.300 1 233 1.5E-42 T 13-10-2018 Astex_1677 3383035f2fb690c2694b3dcd4d4381c7 302 SUPERFAMILY SSF48452 176 263 2.37E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_1677 3383035f2fb690c2694b3dcd4d4381c7 302 Pfam PF13432 Tetratricopeptide repeat 182 246 4.6E-12 T 13-10-2018 Astex_1677 3383035f2fb690c2694b3dcd4d4381c7 302 Gene3D G3DSA:1.25.40.10 177 297 2.1E-13 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_3187 e85a2982c5e3b44b7962643c83aab232 314 Gene3D G3DSA:1.20.1530.20 209 312 6.8E-9 T 13-10-2018 IPR038770 Sodium/solute symporter superfamily Astex_3187 e85a2982c5e3b44b7962643c83aab232 314 Pfam PF03547 Membrane transport protein 165 306 1.0E-14 T 13-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 Astex_2685 b08f59595de3784be4f8da2e1027f98d 304 Pfam PF12006 Protein of unknown function (DUF3500) 4 300 7.0E-74 T 13-10-2018 IPR021889 Protein of unknown function DUF3500 Astex_1611 0809674c5aa926fbe0ac97e595f4ba8c 244 SUPERFAMILY SSF53335 40 219 1.14E-23 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Astex_1611 0809674c5aa926fbe0ac97e595f4ba8c 244 Pfam PF05175 Methyltransferase small domain 42 126 2.4E-8 T 13-10-2018 IPR007848 Methyltransferase small domain GO:0008168 Astex_1611 0809674c5aa926fbe0ac97e595f4ba8c 244 Gene3D G3DSA:3.40.50.150 3 242 1.3E-43 T 13-10-2018 Astex_1611 0809674c5aa926fbe0ac97e595f4ba8c 244 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 115 121 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 Astex_1135 a9a5ef72245877cc2f15af86f9d8f509 177 Pfam PF00583 Acetyltransferase (GNAT) family 52 130 8.3E-10 T 13-10-2018 IPR000182 GNAT domain Astex_1135 a9a5ef72245877cc2f15af86f9d8f509 177 Gene3D G3DSA:3.40.630.30 5 176 1.6E-29 T 13-10-2018 Astex_1135 a9a5ef72245877cc2f15af86f9d8f509 177 SUPERFAMILY SSF55729 14 146 1.54E-17 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Astex_1893 d90cbdccfb215ba6f8723a1244e8afb9 499 Pfam PF04820 Tryptophan halogenase 5 462 4.2E-187 T 13-10-2018 IPR006905 Flavin-dependent halogenase Astex_1893 d90cbdccfb215ba6f8723a1244e8afb9 499 Gene3D G3DSA:3.50.50.60 3 494 4.3E-185 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_1893 d90cbdccfb215ba6f8723a1244e8afb9 499 SUPERFAMILY SSF51905 2 410 7.47E-32 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_1893 d90cbdccfb215ba6f8723a1244e8afb9 499 PIRSF PIRSF011396 3 496 7.8E-194 T 13-10-2018 IPR033856 Flavin-dependent tryptophan halogenase Astex_3145 d284c4c0de527c7147b1a9648a2a0744 247 Gene3D G3DSA:1.10.3580.10 79 246 4.8E-43 T 13-10-2018 IPR023335 ATP12 orthogonal Bundle domain superfamily Astex_3145 d284c4c0de527c7147b1a9648a2a0744 247 Gene3D G3DSA:3.30.2180.30 12 78 1.4E-20 T 13-10-2018 Astex_3145 d284c4c0de527c7147b1a9648a2a0744 247 SUPERFAMILY SSF160909 14 239 4.84E-66 T 13-10-2018 Astex_3145 d284c4c0de527c7147b1a9648a2a0744 247 Pfam PF07542 ATP12 chaperone protein 20 138 4.9E-29 T 13-10-2018 IPR011419 ATP12, ATP synthase F1-assembly protein GO:0043461 Astex_0376 b643ea330ef7985c2ae1fec08da9b864 487 PRINTS PR00113 Alkaline phosphatase signature 116 131 1.9E-39 T 13-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 Astex_0376 b643ea330ef7985c2ae1fec08da9b864 487 PRINTS PR00113 Alkaline phosphatase signature 163 183 1.9E-39 T 13-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 Astex_0376 b643ea330ef7985c2ae1fec08da9b864 487 PRINTS PR00113 Alkaline phosphatase signature 225 235 1.9E-39 T 13-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 Astex_0376 b643ea330ef7985c2ae1fec08da9b864 487 PRINTS PR00113 Alkaline phosphatase signature 60 80 1.9E-39 T 13-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 Astex_0376 b643ea330ef7985c2ae1fec08da9b864 487 PRINTS PR00113 Alkaline phosphatase signature 303 332 1.9E-39 T 13-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 Astex_0376 b643ea330ef7985c2ae1fec08da9b864 487 SUPERFAMILY SSF53649 43 477 4.47E-126 T 13-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 Astex_0376 b643ea330ef7985c2ae1fec08da9b864 487 Gene3D G3DSA:3.40.720.10 31 486 1.2E-144 T 13-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 Astex_0376 b643ea330ef7985c2ae1fec08da9b864 487 SMART SM00098 61 480 7.0E-112 T 13-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 Astex_0376 b643ea330ef7985c2ae1fec08da9b864 487 Pfam PF00245 Alkaline phosphatase 60 477 3.1E-107 T 13-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 Astex_3178 e539b7b60fa2ea0e5d2ab1c0976eb222 1016 Pfam PF07715 TonB-dependent Receptor Plug Domain 63 176 3.0E-13 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_3178 e539b7b60fa2ea0e5d2ab1c0976eb222 1016 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 45 1016 1.2E-197 T 13-10-2018 IPR010104 Bacterial TonB-dependent receptor Astex_3178 e539b7b60fa2ea0e5d2ab1c0976eb222 1016 SUPERFAMILY SSF56935 47 1016 7.33E-79 T 13-10-2018 Astex_3178 e539b7b60fa2ea0e5d2ab1c0976eb222 1016 Gene3D G3DSA:2.170.130.10 38 179 2.1E-14 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_3178 e539b7b60fa2ea0e5d2ab1c0976eb222 1016 Pfam PF00593 TonB dependent receptor 499 1015 1.2E-40 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_3149 7b5892eb4b9fb04fe05464210e93f234 143 PRINTS PR00332 Histidine triad family signature 33 51 6.4E-17 T 13-10-2018 IPR001310 Histidine triad (HIT) protein Astex_3149 7b5892eb4b9fb04fe05464210e93f234 143 PRINTS PR00332 Histidine triad family signature 12 28 6.4E-17 T 13-10-2018 IPR001310 Histidine triad (HIT) protein Astex_3149 7b5892eb4b9fb04fe05464210e93f234 143 PRINTS PR00332 Histidine triad family signature 100 110 6.4E-17 T 13-10-2018 IPR001310 Histidine triad (HIT) protein Astex_3149 7b5892eb4b9fb04fe05464210e93f234 143 Gene3D G3DSA:3.30.428.10 5 143 3.8E-39 T 13-10-2018 IPR036265 HIT-like superfamily Astex_3149 7b5892eb4b9fb04fe05464210e93f234 143 Pfam PF01230 HIT domain 20 113 9.2E-26 T 13-10-2018 IPR001310 Histidine triad (HIT) protein Astex_3149 7b5892eb4b9fb04fe05464210e93f234 143 SUPERFAMILY SSF54197 4 142 3.71E-39 T 13-10-2018 IPR036265 HIT-like superfamily Astex_0494 32189fb1d747d85f71d9689f85d5c5f8 66 Pfam PF04588 Hypoxia induced protein conserved region 9 58 1.9E-10 T 13-10-2018 IPR007667 Hypoxia induced protein, domain Astex_3070 9b3b8b5b76455cdd94a28809a385f57c 482 Pfam PF08386 TAP-like protein 383 469 4.0E-9 T 13-10-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal Astex_3070 9b3b8b5b76455cdd94a28809a385f57c 482 Pfam PF00561 alpha/beta hydrolase fold 93 238 6.8E-19 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Astex_3070 9b3b8b5b76455cdd94a28809a385f57c 482 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 124 135 9.2E-8 T 13-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 Astex_3070 9b3b8b5b76455cdd94a28809a385f57c 482 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 94 102 9.2E-8 T 13-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 Astex_3070 9b3b8b5b76455cdd94a28809a385f57c 482 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 200 214 9.2E-8 T 13-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 Astex_3070 9b3b8b5b76455cdd94a28809a385f57c 482 SUPERFAMILY SSF53474 88 444 4.8E-24 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_2464 7048495437a62d0455bddfe0cad07ceb 207 SUPERFAMILY SSF51735 1 194 4.42E-39 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_2464 7048495437a62d0455bddfe0cad07ceb 207 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 89 9.6E-14 T 13-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal Astex_2464 7048495437a62d0455bddfe0cad07ceb 207 Gene3D G3DSA:3.40.50.720 1 198 3.9E-52 T 13-10-2018 Astex_1697 c67fdbeaab88bfff5474be0df4c1debe 299 SUPERFAMILY SSF53067 115 283 5.4E-41 T 13-10-2018 Astex_1697 c67fdbeaab88bfff5474be0df4c1debe 299 Gene3D G3DSA:3.30.420.40 115 261 2.9E-69 T 13-10-2018 Astex_1697 c67fdbeaab88bfff5474be0df4c1debe 299 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 6 283 8.8E-34 T 13-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 Astex_1697 c67fdbeaab88bfff5474be0df4c1debe 299 Gene3D G3DSA:3.30.420.40 4 114 2.9E-69 T 13-10-2018 Astex_1697 c67fdbeaab88bfff5474be0df4c1debe 299 SUPERFAMILY SSF53067 1 111 1.3E-23 T 13-10-2018 Astex_0477 78d1254d9ad2b62df9bd33e27ce5e3de 253 SUPERFAMILY SSF56235 2 251 1.42E-44 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Astex_0477 78d1254d9ad2b62df9bd33e27ce5e3de 253 Pfam PF13230 Glutamine amidotransferases class-II 1 253 9.4E-112 T 13-10-2018 IPR026869 Putative glutamine amidotransferase type 2 Astex_0477 78d1254d9ad2b62df9bd33e27ce5e3de 253 Gene3D G3DSA:3.60.20.10 1 253 8.7E-95 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal Astex_1815 cc50a8cae518401bbdc1658d9594ebc5 417 Pfam PF08238 Sel1 repeat 127 161 0.5 T 13-10-2018 IPR006597 Sel1-like repeat Astex_1815 cc50a8cae518401bbdc1658d9594ebc5 417 Pfam PF08238 Sel1 repeat 53 87 1.6E-8 T 13-10-2018 IPR006597 Sel1-like repeat Astex_1815 cc50a8cae518401bbdc1658d9594ebc5 417 Pfam PF08238 Sel1 repeat 236 270 1.8E-7 T 13-10-2018 IPR006597 Sel1-like repeat Astex_1815 cc50a8cae518401bbdc1658d9594ebc5 417 Pfam PF08238 Sel1 repeat 198 234 4.2E-7 T 13-10-2018 IPR006597 Sel1-like repeat Astex_1815 cc50a8cae518401bbdc1658d9594ebc5 417 Pfam PF08238 Sel1 repeat 308 342 5.9E-8 T 13-10-2018 IPR006597 Sel1-like repeat Astex_1815 cc50a8cae518401bbdc1658d9594ebc5 417 Pfam PF08238 Sel1 repeat 271 306 1.1E-10 T 13-10-2018 IPR006597 Sel1-like repeat Astex_1815 cc50a8cae518401bbdc1658d9594ebc5 417 Pfam PF08238 Sel1 repeat 162 196 2.0E-8 T 13-10-2018 IPR006597 Sel1-like repeat Astex_1815 cc50a8cae518401bbdc1658d9594ebc5 417 Pfam PF08238 Sel1 repeat 344 377 0.075 T 13-10-2018 IPR006597 Sel1-like repeat Astex_1815 cc50a8cae518401bbdc1658d9594ebc5 417 Pfam PF08238 Sel1 repeat 89 124 7.2E-9 T 13-10-2018 IPR006597 Sel1-like repeat Astex_1815 cc50a8cae518401bbdc1658d9594ebc5 417 SUPERFAMILY SSF81901 42 129 3.4E-21 T 13-10-2018 Astex_1815 cc50a8cae518401bbdc1658d9594ebc5 417 Gene3D G3DSA:1.25.40.10 34 130 1.5E-26 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_1815 cc50a8cae518401bbdc1658d9594ebc5 417 Gene3D G3DSA:1.25.40.10 131 239 2.7E-24 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_1815 cc50a8cae518401bbdc1658d9594ebc5 417 SMART SM00671 162 197 1.3E-8 T 13-10-2018 IPR006597 Sel1-like repeat Astex_1815 cc50a8cae518401bbdc1658d9594ebc5 417 SMART SM00671 343 378 6.6E-4 T 13-10-2018 IPR006597 Sel1-like repeat Astex_1815 cc50a8cae518401bbdc1658d9594ebc5 417 SMART SM00671 198 234 4.3E-4 T 13-10-2018 IPR006597 Sel1-like repeat Astex_1815 cc50a8cae518401bbdc1658d9594ebc5 417 SMART SM00671 53 88 2.9E-9 T 13-10-2018 IPR006597 Sel1-like repeat Astex_1815 cc50a8cae518401bbdc1658d9594ebc5 417 SMART SM00671 235 270 2.9E-6 T 13-10-2018 IPR006597 Sel1-like repeat Astex_1815 cc50a8cae518401bbdc1658d9594ebc5 417 SMART SM00671 307 342 3.8E-7 T 13-10-2018 IPR006597 Sel1-like repeat Astex_1815 cc50a8cae518401bbdc1658d9594ebc5 417 SMART SM00671 89 124 1.6E-9 T 13-10-2018 IPR006597 Sel1-like repeat Astex_1815 cc50a8cae518401bbdc1658d9594ebc5 417 SMART SM00671 125 161 0.012 T 13-10-2018 IPR006597 Sel1-like repeat Astex_1815 cc50a8cae518401bbdc1658d9594ebc5 417 SMART SM00671 271 306 9.1E-10 T 13-10-2018 IPR006597 Sel1-like repeat Astex_1815 cc50a8cae518401bbdc1658d9594ebc5 417 SUPERFAMILY SSF81901 145 382 1.15E-52 T 13-10-2018 Astex_1815 cc50a8cae518401bbdc1658d9594ebc5 417 Gene3D G3DSA:1.25.40.10 254 417 1.8E-42 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_3061 a696a23fa4101334d1e5dc5a27adc3f3 415 SUPERFAMILY SSF47090 344 410 3.92E-11 T 13-10-2018 IPR036365 PGBD-like superfamily Astex_3061 a696a23fa4101334d1e5dc5a27adc3f3 415 Gene3D G3DSA:1.10.101.10 340 411 3.7E-9 T 13-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 Astex_3061 a696a23fa4101334d1e5dc5a27adc3f3 415 Pfam PF01471 Putative peptidoglycan binding domain 358 399 8.0E-9 T 13-10-2018 IPR002477 Peptidoglycan binding-like Astex_0577 d0a9f3cc6e86bbda2e4e264249426a0d 93 Gene3D G3DSA:3.30.2310.20 1 91 2.9E-26 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Astex_0577 d0a9f3cc6e86bbda2e4e264249426a0d 93 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 4 90 2.9E-13 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family Astex_0577 d0a9f3cc6e86bbda2e4e264249426a0d 93 TIGRFAM TIGR02385 RelE_StbE: addiction module toxin, RelE/StbE family 4 87 3.4E-8 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family Astex_1171 3fec623c16ba80b9a5543592ff1ca967 306 SUPERFAMILY SSF103481 203 297 7.45E-13 T 13-10-2018 Astex_1171 3fec623c16ba80b9a5543592ff1ca967 306 SUPERFAMILY SSF103481 50 149 7.85E-9 T 13-10-2018 Astex_1171 3fec623c16ba80b9a5543592ff1ca967 306 Pfam PF00892 EamA-like transporter family 161 294 1.4E-20 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Astex_1171 3fec623c16ba80b9a5543592ff1ca967 306 Pfam PF00892 EamA-like transporter family 12 146 6.3E-17 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Astex_2080 4dd44e6648e5b4a62ecacc13a4781d1b 307 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 10 262 1.4E-38 T 13-10-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system Astex_3385 021120ba1837c14a128ed485cbc22b4f 1084 Gene3D G3DSA:2.170.130.10 40 170 2.6E-12 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_3385 021120ba1837c14a128ed485cbc22b4f 1084 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 39 1084 4.0E-174 T 13-10-2018 IPR010104 Bacterial TonB-dependent receptor Astex_3385 021120ba1837c14a128ed485cbc22b4f 1084 Pfam PF07715 TonB-dependent Receptor Plug Domain 57 166 1.1E-10 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_3385 021120ba1837c14a128ed485cbc22b4f 1084 SUPERFAMILY SSF56935 40 1084 1.54E-60 T 13-10-2018 Astex_3385 021120ba1837c14a128ed485cbc22b4f 1084 Pfam PF00593 TonB dependent receptor 445 1050 2.8E-27 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_1264 75b37db3f29d4cc36f42bcd94c251524 301 Gene3D G3DSA:1.10.10.10 3 87 8.4E-21 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1264 75b37db3f29d4cc36f42bcd94c251524 301 Gene3D G3DSA:3.40.190.10 166 259 2.4E-12 T 13-10-2018 Astex_1264 75b37db3f29d4cc36f42bcd94c251524 301 SUPERFAMILY SSF53850 92 293 1.04E-18 T 13-10-2018 Astex_1264 75b37db3f29d4cc36f42bcd94c251524 301 Pfam PF03466 LysR substrate binding domain 92 292 6.8E-14 T 13-10-2018 IPR005119 LysR, substrate-binding Astex_1264 75b37db3f29d4cc36f42bcd94c251524 301 SUPERFAMILY SSF46785 3 82 1.27E-19 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_1264 75b37db3f29d4cc36f42bcd94c251524 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 61 3.1E-18 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_1264 75b37db3f29d4cc36f42bcd94c251524 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 49 3.4E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_1264 75b37db3f29d4cc36f42bcd94c251524 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 17 28 3.4E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_1264 75b37db3f29d4cc36f42bcd94c251524 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 28 38 3.4E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 Astex_1264 75b37db3f29d4cc36f42bcd94c251524 301 Gene3D G3DSA:3.40.190.10 93 165 2.4E-12 T 13-10-2018 Astex_0963 3d2142eb3dd622d0b68ab2bff59e3cc4 58 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 58 2.1E-23 T 13-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0963 3d2142eb3dd622d0b68ab2bff59e3cc4 58 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 16.929 T 13-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0963 3d2142eb3dd622d0b68ab2bff59e3cc4 58 PIRSF PIRSF002211 1 58 7.6E-22 T 13-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_0963 3d2142eb3dd622d0b68ab2bff59e3cc4 58 Pfam PF00327 Ribosomal protein L30p/L7e 6 54 8.2E-16 T 13-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain Astex_0963 3d2142eb3dd622d0b68ab2bff59e3cc4 58 Gene3D G3DSA:3.30.1390.20 1 58 3.6E-23 T 13-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily Astex_0963 3d2142eb3dd622d0b68ab2bff59e3cc4 58 SUPERFAMILY SSF55129 1 57 3.53E-18 T 13-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily Astex_1615 98e96a234ce53076d0c74a225e7b197f 115 SUPERFAMILY SSF51182 18 113 3.38E-14 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily Astex_1615 98e96a234ce53076d0c74a225e7b197f 115 Pfam PF05899 Protein of unknown function (DUF861) 40 111 5.7E-18 T 13-10-2018 IPR008579 Domain of unknown function DUF861, cupin-3 KEGG: 00230+3.5.3.26|MetaCyc: PWY-5692|MetaCyc: PWY-5698 Astex_1615 98e96a234ce53076d0c74a225e7b197f 115 Gene3D G3DSA:2.60.120.10 4 113 5.4E-22 T 13-10-2018 IPR014710 RmlC-like jelly roll fold Astex_2712 17596561708d920f4ec774f43e484cdb 414 PRINTS PR00173 Glutamate-aspartate symporter signature 3 23 7.9E-37 T 13-10-2018 Astex_2712 17596561708d920f4ec774f43e484cdb 414 PRINTS PR00173 Glutamate-aspartate symporter signature 79 104 7.9E-37 T 13-10-2018 Astex_2712 17596561708d920f4ec774f43e484cdb 414 PRINTS PR00173 Glutamate-aspartate symporter signature 327 346 7.9E-37 T 13-10-2018 Astex_2712 17596561708d920f4ec774f43e484cdb 414 PRINTS PR00173 Glutamate-aspartate symporter signature 354 374 7.9E-37 T 13-10-2018 Astex_2712 17596561708d920f4ec774f43e484cdb 414 PRINTS PR00173 Glutamate-aspartate symporter signature 49 69 7.9E-37 T 13-10-2018 Astex_2712 17596561708d920f4ec774f43e484cdb 414 PRINTS PR00173 Glutamate-aspartate symporter signature 192 211 7.9E-37 T 13-10-2018 Astex_2712 17596561708d920f4ec774f43e484cdb 414 PRINTS PR00173 Glutamate-aspartate symporter signature 292 318 7.9E-37 T 13-10-2018 Astex_2712 17596561708d920f4ec774f43e484cdb 414 Pfam PF00375 Sodium:dicarboxylate symporter family 7 400 2.3E-106 T 13-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Astex_2712 17596561708d920f4ec774f43e484cdb 414 Gene3D G3DSA:1.10.3860.10 1 410 3.1E-113 T 13-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 Astex_2712 17596561708d920f4ec774f43e484cdb 414 SUPERFAMILY SSF118215 6 401 9.15E-107 T 13-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 Astex_1148 62d3218828113e88779e4e28f34063a1 429 Gene3D G3DSA:3.40.50.2000 237 408 2.2E-87 T 13-10-2018 Astex_1148 62d3218828113e88779e4e28f34063a1 429 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 245 399 9.8E-10 T 13-10-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0016758 Reactome: R-HSA-156588 Astex_1148 62d3218828113e88779e4e28f34063a1 429 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 7 62 1.1E-7 T 13-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Astex_1148 62d3218828113e88779e4e28f34063a1 429 Gene3D G3DSA:3.40.50.2000 7 409 2.2E-87 T 13-10-2018 Astex_1148 62d3218828113e88779e4e28f34063a1 429 SUPERFAMILY SSF53756 7 421 1.48E-79 T 13-10-2018 Astex_3336 4e6c04da869d7b496cf6e5decb3cacaf 86 Pfam PF04226 Transglycosylase associated protein 36 83 1.1E-6 T 13-10-2018 IPR007341 Transglycosylase-associated protein GO:0016021 Astex_3555 a94979e39aed8c7dc2a12e106e4fe965 661 SUPERFAMILY SSF50993 40 294 2.04E-7 T 13-10-2018 Astex_3555 a94979e39aed8c7dc2a12e106e4fe965 661 SUPERFAMILY SSF53474 409 654 1.39E-53 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_3555 a94979e39aed8c7dc2a12e106e4fe965 661 Pfam PF00326 Prolyl oligopeptidase family 462 634 5.8E-31 T 13-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 Astex_3555 a94979e39aed8c7dc2a12e106e4fe965 661 Gene3D G3DSA:3.40.50.1820 399 657 1.8E-58 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1404 1657c2881367dde743829790dce46184 200 Gene3D G3DSA:3.40.50.1240 12 197 1.2E-13 T 13-10-2018 IPR029033 Histidine phosphatase superfamily Astex_1404 1657c2881367dde743829790dce46184 200 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 15 175 1.7E-8 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 Astex_1404 1657c2881367dde743829790dce46184 200 SUPERFAMILY SSF53254 14 199 6.28E-19 T 13-10-2018 IPR029033 Histidine phosphatase superfamily Astex_0858 82f29d08fe45a63d1e02ae73d6f19f6f 517 Gene3D G3DSA:3.50.50.60 12 391 2.7E-120 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_0858 82f29d08fe45a63d1e02ae73d6f19f6f 517 Gene3D G3DSA:1.20.58.100 417 502 6.8E-15 T 13-10-2018 Astex_0858 82f29d08fe45a63d1e02ae73d6f19f6f 517 SUPERFAMILY SSF56425 227 339 2.99E-32 T 13-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 Astex_0858 82f29d08fe45a63d1e02ae73d6f19f6f 517 SUPERFAMILY SSF51905 12 405 2.83E-50 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_0858 82f29d08fe45a63d1e02ae73d6f19f6f 517 Pfam PF00890 FAD binding domain 12 379 4.3E-74 T 13-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 Astex_0858 82f29d08fe45a63d1e02ae73d6f19f6f 517 SUPERFAMILY SSF46977 421 506 6.93E-19 T 13-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Astex_0858 82f29d08fe45a63d1e02ae73d6f19f6f 517 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 2.2E-6 T 13-10-2018 Astex_0858 82f29d08fe45a63d1e02ae73d6f19f6f 517 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 342 364 2.2E-6 T 13-10-2018 Astex_0858 82f29d08fe45a63d1e02ae73d6f19f6f 517 Gene3D G3DSA:3.90.700.10 237 345 2.7E-120 T 13-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 Astex_0858 82f29d08fe45a63d1e02ae73d6f19f6f 517 Pfam PF02910 Fumarate reductase flavoprotein C-term 464 492 7.0E-7 T 13-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 Astex_1239 867838a3b85d56e541fe19305f299713 99 Pfam PF02699 Preprotein translocase subunit 8 83 1.9E-26 T 13-10-2018 IPR003849 Preprotein translocase YajC Astex_1239 867838a3b85d56e541fe19305f299713 99 PRINTS PR01853 Bacterial YajC preprotein translocase signature 6 26 3.1E-13 T 13-10-2018 IPR003849 Preprotein translocase YajC Astex_1239 867838a3b85d56e541fe19305f299713 99 PRINTS PR01853 Bacterial YajC preprotein translocase signature 44 62 3.1E-13 T 13-10-2018 IPR003849 Preprotein translocase YajC Astex_1239 867838a3b85d56e541fe19305f299713 99 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 6 85 2.5E-22 T 13-10-2018 IPR003849 Preprotein translocase YajC Astex_1239 867838a3b85d56e541fe19305f299713 99 SMART SM01323 4 86 5.8E-39 T 13-10-2018 IPR003849 Preprotein translocase YajC Astex_3128 9fb2e218c3cdecced11db20a02ea8996 591 Gene3D G3DSA:1.10.530.10 426 583 1.8E-35 T 13-10-2018 Astex_3128 9fb2e218c3cdecced11db20a02ea8996 591 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 440 468 - T 13-10-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 Astex_3128 9fb2e218c3cdecced11db20a02ea8996 591 SUPERFAMILY SSF53955 429 573 2.68E-35 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily Astex_3128 9fb2e218c3cdecced11db20a02ea8996 591 SUPERFAMILY SSF48435 237 389 5.36E-15 T 13-10-2018 IPR008939 Lytic transglycosylase, superhelical U-shaped GO:0004553|GO:0042597 Astex_3128 9fb2e218c3cdecced11db20a02ea8996 591 Pfam PF01464 Transglycosylase SLT domain 426 534 6.6E-23 T 13-10-2018 IPR008258 Transglycosylase SLT domain 1 Astex_3128 9fb2e218c3cdecced11db20a02ea8996 591 SUPERFAMILY SSF48435 93 160 3.66E-8 T 13-10-2018 IPR008939 Lytic transglycosylase, superhelical U-shaped GO:0004553|GO:0042597 Astex_0311 651ecb0e63e796a668660cdef61c26a7 158 Pfam PF10073 Uncharacterized protein conserved in bacteria (DUF2312) 85 156 2.5E-33 T 13-10-2018 IPR018753 Azospirillum phage Cd, Gp10 Astex_0762 3a7a1696bbcb9a72c223a353f5a4f51a 168 Pfam PF13523 Acetyltransferase (GNAT) domain 9 150 2.6E-24 T 13-10-2018 Astex_0762 3a7a1696bbcb9a72c223a353f5a4f51a 168 Gene3D G3DSA:3.40.630.30 1 165 2.0E-35 T 13-10-2018 Astex_0762 3a7a1696bbcb9a72c223a353f5a4f51a 168 SUPERFAMILY SSF55729 2 160 1.88E-28 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Astex_0794 a96aabe722e7e31203b751546f4ea07b 358 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 5 124 2.6E-10 T 13-10-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 Astex_0794 a96aabe722e7e31203b751546f4ea07b 358 SUPERFAMILY SSF51735 4 133 7.3E-17 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_0794 a96aabe722e7e31203b751546f4ea07b 358 Gene3D G3DSA:3.40.50.720 3 140 3.4E-27 T 13-10-2018 Astex_2136 0aa328535cd5c8dd4de9c27e92adb2ef 290 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 72 279 6.1E-69 T 13-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 Astex_2136 0aa328535cd5c8dd4de9c27e92adb2ef 290 Gene3D G3DSA:3.90.850.10 67 285 2.0E-82 T 13-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 Astex_2136 0aa328535cd5c8dd4de9c27e92adb2ef 290 SUPERFAMILY SSF56529 60 280 2.22E-78 T 13-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 Astex_1482 94b4ea860780e4ccc6b28c18804a1234 410 Gene3D G3DSA:3.90.120.30 274 364 1.3E-35 T 13-10-2018 Astex_1482 94b4ea860780e4ccc6b28c18804a1234 410 ProSitePatterns PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. 374 392 - T 13-10-2018 IPR031303 DNA methylase, C-5 cytosine-specific, conserved site KEGG: 00270+2.1.1.37 Astex_1482 94b4ea860780e4ccc6b28c18804a1234 410 SMART SM00530 5 58 5.0E-4 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Astex_1482 94b4ea860780e4ccc6b28c18804a1234 410 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 68 390 9.2E-96 T 13-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 Astex_1482 94b4ea860780e4ccc6b28c18804a1234 410 SUPERFAMILY SSF53335 66 394 4.16E-85 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Astex_1482 94b4ea860780e4ccc6b28c18804a1234 410 Pfam PF01381 Helix-turn-helix 9 42 3.8E-8 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Astex_1482 94b4ea860780e4ccc6b28c18804a1234 410 Gene3D G3DSA:1.10.260.40 1 53 6.3E-9 T 13-10-2018 Astex_1482 94b4ea860780e4ccc6b28c18804a1234 410 SUPERFAMILY SSF47413 8 54 5.9E-8 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Astex_1482 94b4ea860780e4ccc6b28c18804a1234 410 Gene3D G3DSA:3.40.50.150 65 270 1.7E-73 T 13-10-2018 Astex_1482 94b4ea860780e4ccc6b28c18804a1234 410 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 129 141 - T 13-10-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-4655427|Reactome: R-HSA-5334118 Astex_1482 94b4ea860780e4ccc6b28c18804a1234 410 Pfam PF00145 C-5 cytosine-specific DNA methylase 66 390 2.3E-82 T 13-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 Astex_1482 94b4ea860780e4ccc6b28c18804a1234 410 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 177 191 1.5E-15 T 13-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 Astex_1482 94b4ea860780e4ccc6b28c18804a1234 410 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 223 236 1.5E-15 T 13-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 Astex_1482 94b4ea860780e4ccc6b28c18804a1234 410 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 67 83 1.5E-15 T 13-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 Astex_0479 8f9a4ef497ed8168888a50eb98546d9f 252 PIRSF PIRSF028756 1 250 1.4E-100 T 13-10-2018 IPR016898 Polyphosphate kinase 2 KEGG: 00190+2.7.4.1 Astex_0479 8f9a4ef497ed8168888a50eb98546d9f 252 SUPERFAMILY SSF52540 33 219 6.14E-21 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0479 8f9a4ef497ed8168888a50eb98546d9f 252 TIGRFAM TIGR03707 PPK2_P_aer: polyphosphate kinase 2 1 221 1.1E-96 T 13-10-2018 IPR022486 Polyphosphate kinase 2, PA0141 GO:0006793|GO:0008976 KEGG: 00190+2.7.4.1 Astex_0479 8f9a4ef497ed8168888a50eb98546d9f 252 Gene3D G3DSA:3.40.50.300 1 246 1.7E-83 T 13-10-2018 Astex_0479 8f9a4ef497ed8168888a50eb98546d9f 252 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 2 221 4.6E-93 T 13-10-2018 IPR022488 Polyphosphate kinase-2-related Astex_1910 58973862f281e6133cf99ac0ea81d7cd 299 SUPERFAMILY SSF63829 3 293 5.23E-66 T 13-10-2018 Astex_1910 58973862f281e6133cf99ac0ea81d7cd 299 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 17 263 1.2E-76 T 13-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region Astex_1910 58973862f281e6133cf99ac0ea81d7cd 299 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 94 115 3.3E-29 T 13-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) Astex_1910 58973862f281e6133cf99ac0ea81d7cd 299 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 157 177 3.3E-29 T 13-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) Astex_1910 58973862f281e6133cf99ac0ea81d7cd 299 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 18 35 3.3E-29 T 13-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) Astex_1910 58973862f281e6133cf99ac0ea81d7cd 299 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 203 220 3.3E-29 T 13-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) Astex_1910 58973862f281e6133cf99ac0ea81d7cd 299 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 245 263 3.3E-29 T 13-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) Astex_1910 58973862f281e6133cf99ac0ea81d7cd 299 Gene3D G3DSA:2.120.10.30 3 298 5.6E-95 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like Astex_2074 960384064daee8382648f550e3470382 435 SUPERFAMILY SSF53300 283 427 7.12E-12 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Astex_2074 960384064daee8382648f550e3470382 435 Gene3D G3DSA:3.40.50.410 284 430 2.5E-6 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily Astex_2074 960384064daee8382648f550e3470382 435 Pfam PF05731 TROVE domain 160 243 1.5E-6 T 13-10-2018 IPR008858 TROVE domain GO:0003723 Astex_2074 960384064daee8382648f550e3470382 435 SUPERFAMILY SSF140864 11 260 7.85E-37 T 13-10-2018 IPR037214 TROVE domain superfamily Astex_3202 a8d52bea821dff58da6c552b4c40c578 279 SUPERFAMILY SSF51735 5 268 1.67E-26 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_3202 a8d52bea821dff58da6c552b4c40c578 279 Pfam PF01370 NAD dependent epimerase/dehydratase family 63 192 2.3E-5 T 13-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 Astex_3202 a8d52bea821dff58da6c552b4c40c578 279 Gene3D G3DSA:3.40.50.720 5 263 9.8E-26 T 13-10-2018 Astex_3794 e2b20c9185bd614431ce7542dfa07cfb 336 Pfam PF06834 TraU protein 32 335 4.4E-111 T 13-10-2018 IPR009649 TraU Astex_0905 9fd68b8ed39cc7e2e2daebdfef078ce2 686 Gene3D G3DSA:2.40.170.20 169 686 1.8E-57 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_0905 9fd68b8ed39cc7e2e2daebdfef078ce2 686 Pfam PF00593 TonB dependent receptor 224 685 1.5E-34 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_0905 9fd68b8ed39cc7e2e2daebdfef078ce2 686 Pfam PF07715 TonB-dependent Receptor Plug Domain 52 156 1.0E-19 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_0905 9fd68b8ed39cc7e2e2daebdfef078ce2 686 SUPERFAMILY SSF56935 39 686 5.86E-88 T 13-10-2018 Astex_0905 9fd68b8ed39cc7e2e2daebdfef078ce2 686 Gene3D G3DSA:2.170.130.10 50 165 1.8E-28 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_1164 5dc514999a19ba3127fe323825174a58 152 Gene3D G3DSA:2.20.25.10 1 48 7.5E-19 T 13-10-2018 Astex_1164 5dc514999a19ba3127fe323825174a58 152 SUPERFAMILY SSF82784 6 139 2.49E-42 T 13-10-2018 IPR036102 OsmC/Ohr superfamily Astex_1164 5dc514999a19ba3127fe323825174a58 152 Pfam PF02566 OsmC-like protein 43 139 1.0E-15 T 13-10-2018 IPR003718 OsmC/Ohr family Astex_1164 5dc514999a19ba3127fe323825174a58 152 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 8 139 3.1E-53 T 13-10-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 Astex_1164 5dc514999a19ba3127fe323825174a58 152 Gene3D G3DSA:3.30.300.20 49 140 1.3E-31 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta Astex_3286 76994c06fbbf9ccec90decd5cde1d92b 157 Gene3D G3DSA:1.10.150.120 74 157 2.8E-26 T 13-10-2018 Astex_3286 76994c06fbbf9ccec90decd5cde1d92b 157 SUPERFAMILY SSF54292 2 76 6.82E-27 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 Astex_3286 76994c06fbbf9ccec90decd5cde1d92b 157 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 5 61 2.0E-7 T 13-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 Astex_3286 76994c06fbbf9ccec90decd5cde1d92b 157 SUPERFAMILY SSF47741 82 149 6.93E-30 T 13-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily Astex_3286 76994c06fbbf9ccec90decd5cde1d92b 157 Gene3D G3DSA:3.10.20.30 1 73 3.3E-28 T 13-10-2018 IPR012675 Beta-grasp domain superfamily Astex_3286 76994c06fbbf9ccec90decd5cde1d92b 157 Pfam PF01799 [2Fe-2S] binding domain 71 144 3.7E-27 T 13-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 Astex_3286 76994c06fbbf9ccec90decd5cde1d92b 157 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 37 45 - T 13-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 Astex_0825 240ccddb7817aa5f6509fbee8f465ad8 294 Gene3D G3DSA:1.10.3720.10 27 288 1.0E-55 T 13-10-2018 IPR035906 MetI-like superfamily Astex_0825 240ccddb7817aa5f6509fbee8f465ad8 294 SUPERFAMILY SSF161098 23 282 2.35E-60 T 13-10-2018 IPR035906 MetI-like superfamily Astex_0825 240ccddb7817aa5f6509fbee8f465ad8 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 277 3.4E-20 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Astex_3140 065812abca147eb44cb4f37877a02bd2 437 SUPERFAMILY SSF58104 116 430 8.89E-54 T 13-10-2018 Astex_3140 065812abca147eb44cb4f37877a02bd2 437 SMART SM00283 177 431 5.6E-44 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_3140 065812abca147eb44cb4f37877a02bd2 437 Gene3D G3DSA:1.10.287.950 142 436 7.2E-49 T 13-10-2018 Astex_3140 065812abca147eb44cb4f37877a02bd2 437 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 198 227 3.8E-18 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_3140 065812abca147eb44cb4f37877a02bd2 437 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 304 333 3.8E-18 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_3140 065812abca147eb44cb4f37877a02bd2 437 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 275 302 3.8E-18 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_3140 065812abca147eb44cb4f37877a02bd2 437 SMART SM00304 87 140 0.0041 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Astex_3140 065812abca147eb44cb4f37877a02bd2 437 Gene3D G3DSA:1.10.8.500 93 138 2.3E-10 T 13-10-2018 Astex_3140 065812abca147eb44cb4f37877a02bd2 437 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 250 398 8.3E-31 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_1604 a8362bf845183b9825fab7a7188aa9f0 793 SUPERFAMILY SSF56935 50 793 1.01E-117 T 13-10-2018 Astex_1604 a8362bf845183b9825fab7a7188aa9f0 793 Pfam PF07715 TonB-dependent Receptor Plug Domain 65 174 1.5E-14 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_1604 a8362bf845183b9825fab7a7188aa9f0 793 Pfam PF00593 TonB dependent receptor 296 790 7.1E-39 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_1604 a8362bf845183b9825fab7a7188aa9f0 793 Gene3D G3DSA:2.40.170.20 56 793 3.9E-155 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_2826 2d22f10be8c386c6bb0e33460f037a0c 266 Gene3D G3DSA:2.130.10.10 21 245 1.2E-8 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 Astex_2826 2d22f10be8c386c6bb0e33460f037a0c 266 SUPERFAMILY SSF50969 30 262 8.63E-21 T 13-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like Astex_2826 2d22f10be8c386c6bb0e33460f037a0c 266 Pfam PF05096 Glutamine cyclotransferase 13 254 1.4E-95 T 13-10-2018 IPR007788 Glutaminyl-peptide cyclotransferase GO:0016603|GO:0017186 MetaCyc: PWY-7942 Astex_2711 20c25800ed92e7c2dc2773a78c550e7e 230 Gene3D G3DSA:3.40.50.150 31 187 1.4E-24 T 13-10-2018 Astex_2711 20c25800ed92e7c2dc2773a78c550e7e 230 Pfam PF13489 Methyltransferase domain 33 176 5.6E-12 T 13-10-2018 Astex_2711 20c25800ed92e7c2dc2773a78c550e7e 230 SUPERFAMILY SSF53335 54 229 1.21E-26 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Astex_1590 46681245a2139dceaa526b9c77db81b6 112 Gene3D G3DSA:3.10.180.10 6 111 3.4E-16 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Astex_1590 46681245a2139dceaa526b9c77db81b6 112 SUPERFAMILY SSF54593 5 111 3.89E-18 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Astex_1487 38b649f489066569ef2680a49049b8fd 190 SUPERFAMILY SSF52540 5 165 7.56E-10 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_1487 38b649f489066569ef2680a49049b8fd 190 Pfam PF13207 AAA domain 9 128 4.2E-13 T 13-10-2018 Astex_1487 38b649f489066569ef2680a49049b8fd 190 Gene3D G3DSA:3.40.50.300 1 182 6.3E-36 T 13-10-2018 Astex_1533 53f9837ed9bc175fddaa933b2c8393f7 289 SUPERFAMILY SSF53955 23 108 2.31E-12 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily Astex_1533 53f9837ed9bc175fddaa933b2c8393f7 289 Pfam PF01464 Transglycosylase SLT domain 25 79 1.8E-7 T 13-10-2018 IPR008258 Transglycosylase SLT domain 1 Astex_1533 53f9837ed9bc175fddaa933b2c8393f7 289 Gene3D G3DSA:1.10.530.10 13 210 6.3E-57 T 13-10-2018 Astex_2858 42408dae10dede63df2621355bdae79d 397 Gene3D G3DSA:3.40.710.10 38 386 1.8E-82 T 13-10-2018 Astex_2858 42408dae10dede63df2621355bdae79d 397 Pfam PF00144 Beta-lactamase 46 378 3.8E-58 T 13-10-2018 IPR001466 Beta-lactamase-related Astex_2858 42408dae10dede63df2621355bdae79d 397 SUPERFAMILY SSF56601 42 374 1.01E-76 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like Astex_1911 03f95d6524c679b3c0c63773d7850c9e 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 7.7E-29 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1911 03f95d6524c679b3c0c63773d7850c9e 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 7.7E-29 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1911 03f95d6524c679b3c0c63773d7850c9e 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 7.7E-29 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1911 03f95d6524c679b3c0c63773d7850c9e 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 7.7E-29 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1911 03f95d6524c679b3c0c63773d7850c9e 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 7.7E-29 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1911 03f95d6524c679b3c0c63773d7850c9e 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 7.7E-29 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1911 03f95d6524c679b3c0c63773d7850c9e 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 4.3E-9 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1911 03f95d6524c679b3c0c63773d7850c9e 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 4.3E-9 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1911 03f95d6524c679b3c0c63773d7850c9e 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 4.3E-9 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1911 03f95d6524c679b3c0c63773d7850c9e 249 Gene3D G3DSA:3.40.50.720 8 249 3.2E-59 T 13-10-2018 Astex_1911 03f95d6524c679b3c0c63773d7850c9e 249 SUPERFAMILY SSF51735 10 248 1.85E-63 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_1911 03f95d6524c679b3c0c63773d7850c9e 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 248 3.4E-46 T 13-10-2018 Astex_0831 0d9515ba5f6a81cf75193d5cb5c0f9bd 111 Pfam PF00893 Small Multidrug Resistance protein 7 99 1.7E-27 T 13-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 Astex_0831 0d9515ba5f6a81cf75193d5cb5c0f9bd 111 Gene3D G3DSA:1.10.3730.20 7 111 4.9E-29 T 13-10-2018 Astex_0831 0d9515ba5f6a81cf75193d5cb5c0f9bd 111 SUPERFAMILY SSF103481 11 107 5.89E-16 T 13-10-2018 Astex_2834 382bada1762007041f7aae2b6df2ddf8 158 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 10 146 2.3E-56 T 13-10-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 Astex_2834 382bada1762007041f7aae2b6df2ddf8 158 Gene3D G3DSA:3.90.1180.10 7 153 1.1E-56 T 13-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 Astex_2834 382bada1762007041f7aae2b6df2ddf8 158 Pfam PF00572 Ribosomal protein L13 17 143 4.3E-52 T 13-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 Astex_2834 382bada1762007041f7aae2b6df2ddf8 158 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 18 146 27.617 T 13-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 Astex_2834 382bada1762007041f7aae2b6df2ddf8 158 PIRSF PIRSF002181 2 157 9.0E-48 T 13-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 Astex_2834 382bada1762007041f7aae2b6df2ddf8 158 SUPERFAMILY SSF52161 9 148 3.4E-54 T 13-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 Astex_3433 a743e250d62f5569dead899bacd667f3 246 Pfam PF00196 Bacterial regulatory proteins, luxR family 185 238 3.5E-6 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Astex_3433 a743e250d62f5569dead899bacd667f3 246 SMART SM00421 182 239 1.2E-4 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 Astex_3433 a743e250d62f5569dead899bacd667f3 246 SUPERFAMILY SSF46894 174 245 4.08E-10 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Astex_3433 a743e250d62f5569dead899bacd667f3 246 SUPERFAMILY SSF75516 31 164 4.32E-9 T 13-10-2018 IPR036693 Transcription factor LuxR-like, autoinducer-binding domain superfamily Astex_3433 a743e250d62f5569dead899bacd667f3 246 Pfam PF03472 Autoinducer binding domain 31 165 1.3E-6 T 13-10-2018 IPR005143 Transcription factor LuxR-like, autoinducer-binding domain Astex_3433 a743e250d62f5569dead899bacd667f3 246 Gene3D G3DSA:1.10.10.10 179 245 2.0E-10 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_2566 d88b3eb517c8ce17c67ff2ea4128ab10 89 Pfam PF03693 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH 13 50 3.2E-11 T 13-10-2018 IPR022789 Antitoxin ParD Astex_2566 d88b3eb517c8ce17c67ff2ea4128ab10 89 SUPERFAMILY SSF47598 4 48 2.45E-10 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 Astex_2566 d88b3eb517c8ce17c67ff2ea4128ab10 89 TIGRFAM TIGR02606 antidote_CC2985: putative addiction module antidote protein, CC2985 family 8 50 8.6E-15 T 13-10-2018 IPR022789 Antitoxin ParD Astex_2566 d88b3eb517c8ce17c67ff2ea4128ab10 89 Gene3D G3DSA:1.10.8.1250 14 87 8.4E-13 T 13-10-2018 IPR038296 Antitoxin ParD superfamily Astex_1200 1da6ae1c05daa4388844150a4fd8f4eb 78 SUPERFAMILY SSF47413 4 71 1.3E-15 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Astex_1200 1da6ae1c05daa4388844150a4fd8f4eb 78 Gene3D G3DSA:1.10.260.40 8 76 1.8E-7 T 13-10-2018 Astex_1200 1da6ae1c05daa4388844150a4fd8f4eb 78 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 7 68 2.6E-22 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Astex_2133 161c71e12d29ee462a4e33d1cdab977e 259 Gene3D G3DSA:3.40.50.720 1 257 2.6E-76 T 13-10-2018 Astex_2133 161c71e12d29ee462a4e33d1cdab977e 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 253 1.9E-60 T 13-10-2018 Astex_2133 161c71e12d29ee462a4e33d1cdab977e 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 3.0E-8 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2133 161c71e12d29ee462a4e33d1cdab977e 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 3.0E-8 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2133 161c71e12d29ee462a4e33d1cdab977e 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 3.0E-8 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2133 161c71e12d29ee462a4e33d1cdab977e 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 2.5E-39 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2133 161c71e12d29ee462a4e33d1cdab977e 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 2.5E-39 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2133 161c71e12d29ee462a4e33d1cdab977e 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 2.5E-39 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2133 161c71e12d29ee462a4e33d1cdab977e 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 2.5E-39 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2133 161c71e12d29ee462a4e33d1cdab977e 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 2.5E-39 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2133 161c71e12d29ee462a4e33d1cdab977e 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.5E-39 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_2133 161c71e12d29ee462a4e33d1cdab977e 259 SUPERFAMILY SSF51735 4 255 4.12E-78 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_0080 592aef2de5f2460def2afb799565dbd4 357 Gene3D G3DSA:3.30.200.20 1 117 2.1E-23 T 13-10-2018 Astex_0080 592aef2de5f2460def2afb799565dbd4 357 Pfam PF01636 Phosphotransferase enzyme family 24 278 3.0E-23 T 13-10-2018 IPR002575 Aminoglycoside phosphotransferase Astex_0080 592aef2de5f2460def2afb799565dbd4 357 Gene3D G3DSA:3.90.1200.10 118 353 1.4E-60 T 13-10-2018 Astex_0080 592aef2de5f2460def2afb799565dbd4 357 SUPERFAMILY SSF56112 10 346 1.44E-44 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily Astex_0614 39a08827e213c23bd48c3aa6e91f0a50 121 Pfam PF00072 Response regulator receiver domain 5 113 1.5E-28 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_0614 39a08827e213c23bd48c3aa6e91f0a50 121 Gene3D G3DSA:3.40.50.12740 2 119 3.3E-35 T 13-10-2018 Astex_0614 39a08827e213c23bd48c3aa6e91f0a50 121 SUPERFAMILY SSF52172 1 116 4.13E-35 T 13-10-2018 IPR011006 CheY-like superfamily Astex_0614 39a08827e213c23bd48c3aa6e91f0a50 121 SMART SM00448 2 115 1.6E-34 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_3278 6bebc28e921c2bbb9efbdf1940b5fce8 318 SUPERFAMILY SSF52540 10 289 6.05E-43 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_3278 6bebc28e921c2bbb9efbdf1940b5fce8 318 PIRSF PIRSF002849 1 318 8.4E-125 T 13-10-2018 Astex_3278 6bebc28e921c2bbb9efbdf1940b5fce8 318 SMART SM00382 37 178 1.7E-5 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_3278 6bebc28e921c2bbb9efbdf1940b5fce8 318 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 40 170 5.5E-62 T 13-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 Astex_3278 6bebc28e921c2bbb9efbdf1940b5fce8 318 Gene3D G3DSA:1.10.8.300 207 314 8.0E-28 T 13-10-2018 Astex_3278 6bebc28e921c2bbb9efbdf1940b5fce8 318 Gene3D G3DSA:3.40.50.300 3 206 5.1E-50 T 13-10-2018 Astex_3248 07f15bc60368714355dc425cca213595 679 Pfam PF11412 Disulphide bond corrector protein DsbC 36 148 3.7E-17 T 13-10-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain Astex_3248 07f15bc60368714355dc425cca213595 679 Pfam PF13899 Thioredoxin-like 577 654 2.2E-12 T 13-10-2018 Astex_3248 07f15bc60368714355dc425cca213595 679 SUPERFAMILY SSF52833 575 659 1.62E-11 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Astex_3248 07f15bc60368714355dc425cca213595 679 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 297 479 2.8E-7 T 13-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 Astex_3248 07f15bc60368714355dc425cca213595 679 Gene3D G3DSA:3.40.30.10 565 675 9.4E-10 T 13-10-2018 Astex_3248 07f15bc60368714355dc425cca213595 679 ProSitePatterns PS00194 Thioredoxin family active site. 589 607 - T 13-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 Astex_0430 2d23c0d85f40c78abc373608b34dff6d 184 Pfam PF07811 TadE-like protein 18 57 2.2E-7 T 13-10-2018 IPR012495 TadE-like Astex_0068 d6bed4919d904647c82ee0e502b42a6b 123 SUPERFAMILY SSF47473 26 107 9.62E-12 T 13-10-2018 IPR011992 EF-hand domain pair Astex_0068 d6bed4919d904647c82ee0e502b42a6b 123 ProSitePatterns PS00018 EF-hand calcium-binding domain. 92 104 - T 13-10-2018 IPR018247 EF-Hand 1, calcium-binding site Astex_0068 d6bed4919d904647c82ee0e502b42a6b 123 Gene3D G3DSA:1.10.238.10 18 120 5.9E-12 T 13-10-2018 Astex_0068 d6bed4919d904647c82ee0e502b42a6b 123 Pfam PF13499 EF-hand domain pair 45 106 3.2E-7 T 13-10-2018 IPR002048 EF-hand domain GO:0005509 Astex_2910 004d401f3da7752659d8bd4e805c3bdf 151 Gene3D G3DSA:3.30.530.20 1 149 1.9E-37 T 13-10-2018 IPR023393 START-like domain superfamily Astex_2910 004d401f3da7752659d8bd4e805c3bdf 151 SUPERFAMILY SSF55961 3 149 7.02E-28 T 13-10-2018 Astex_2910 004d401f3da7752659d8bd4e805c3bdf 151 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 135 2.6E-21 T 13-10-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 Astex_0651 0808df95fd16463bbf90aef78c91213a 429 SUPERFAMILY SSF51905 9 312 3.81E-26 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_0651 0808df95fd16463bbf90aef78c91213a 429 Gene3D G3DSA:3.50.50.100 5 421 1.0E-144 T 13-10-2018 Astex_0651 0808df95fd16463bbf90aef78c91213a 429 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 9 314 2.8E-18 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 Astex_0651 0808df95fd16463bbf90aef78c91213a 429 SUPERFAMILY SSF51905 129 247 1.75E-6 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_0835 91799425d803089a33fafd516f092d4f 492 Pfam PF08811 Protein of unknown function (DUF1800) 10 491 6.6E-128 T 13-10-2018 IPR014917 Protein of unknown function DUF1800 Astex_3329 86d0ee951d4ae69d293298d786cfada1 165 Pfam PF01850 PIN domain 2 117 2.0E-5 T 13-10-2018 IPR002716 PIN domain Astex_3329 86d0ee951d4ae69d293298d786cfada1 165 Gene3D G3DSA:3.40.50.1010 1 135 3.3E-23 T 13-10-2018 Astex_3329 86d0ee951d4ae69d293298d786cfada1 165 SUPERFAMILY SSF88723 1 134 2.02E-15 T 13-10-2018 IPR029060 PIN-like domain superfamily Astex_2355 e64330c00809f3c5de713f21ac5d521e 472 Pfam PF07394 Protein of unknown function (DUF1501) 48 452 7.6E-44 T 13-10-2018 IPR010869 Protein of unknown function DUF1501 Astex_1385 8c6a5027ecf0d16cc7c3e51ba0041626 537 Gene3D G3DSA:2.60.120.200 358 536 2.2E-17 T 13-10-2018 Astex_1385 8c6a5027ecf0d16cc7c3e51ba0041626 537 SUPERFAMILY SSF75005 53 336 3.66E-73 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Astex_1385 8c6a5027ecf0d16cc7c3e51ba0041626 537 Gene3D G3DSA:2.115.10.20 51 341 9.3E-72 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Astex_1385 8c6a5027ecf0d16cc7c3e51ba0041626 537 Pfam PF04616 Glycosyl hydrolases family 43 54 328 1.5E-83 T 13-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 Astex_1385 8c6a5027ecf0d16cc7c3e51ba0041626 537 SUPERFAMILY SSF49899 357 535 8.71E-23 T 13-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily Astex_2255 54331f3283d687ad9806a5ac525752d8 408 SUPERFAMILY SSF102114 46 193 4.05E-13 T 13-10-2018 Astex_2255 54331f3283d687ad9806a5ac525752d8 408 SUPERFAMILY SSF47781 306 380 9.89E-10 T 13-10-2018 IPR010994 RuvA domain 2-like Astex_2255 54331f3283d687ad9806a5ac525752d8 408 SMART SM00729 57 283 0.0018 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Astex_2255 54331f3283d687ad9806a5ac525752d8 408 TIGRFAM TIGR03916 rSAM_link_UDG: putative DNA modification/repair radical SAM protein 5 397 4.3E-172 T 13-10-2018 IPR023874 DNA modification/repair radical SAM protein, putative Astex_2255 54331f3283d687ad9806a5ac525752d8 408 Gene3D G3DSA:3.20.20.70 52 195 1.4E-8 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_3304 b57d22fc170ec57432a8eb19b7760951 910 Pfam PF07715 TonB-dependent Receptor Plug Domain 50 170 6.5E-25 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_3304 b57d22fc170ec57432a8eb19b7760951 910 SUPERFAMILY SSF56935 38 909 7.12E-95 T 13-10-2018 Astex_3304 b57d22fc170ec57432a8eb19b7760951 910 Pfam PF00593 TonB dependent receptor 355 909 2.6E-43 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_3304 b57d22fc170ec57432a8eb19b7760951 910 Gene3D G3DSA:2.170.130.10 32 174 9.2E-35 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_1562 e4f1ed9848cea7018c1e7feb7e051f1f 122 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 42 71 - T 13-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 Astex_1562 e4f1ed9848cea7018c1e7feb7e051f1f 122 Gene3D G3DSA:2.40.50.100 1 122 7.5E-44 T 13-10-2018 Astex_1562 e4f1ed9848cea7018c1e7feb7e051f1f 122 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 1 120 37.35 T 13-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 Astex_1562 e4f1ed9848cea7018c1e7feb7e051f1f 122 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 1 120 4.8E-44 T 13-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 Astex_1562 e4f1ed9848cea7018c1e7feb7e051f1f 122 Pfam PF01597 Glycine cleavage H-protein 2 120 4.5E-44 T 13-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate Astex_1562 e4f1ed9848cea7018c1e7feb7e051f1f 122 SUPERFAMILY SSF51230 1 119 1.81E-39 T 13-10-2018 IPR011053 Single hybrid motif Astex_3441 e2e2dd40efd1c452fa1a6bba01491dc3 251 TIGRFAM TIGR00781 ccoO: cytochrome c oxidase, cbb3-type, subunit II 6 239 1.8E-100 T 13-10-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO Astex_3441 e2e2dd40efd1c452fa1a6bba01491dc3 251 Pfam PF02433 Cytochrome C oxidase, mono-heme subunit/FixO 5 232 2.6E-95 T 13-10-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO Astex_3441 e2e2dd40efd1c452fa1a6bba01491dc3 251 SUPERFAMILY SSF46626 16 228 1.21E-24 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Astex_2330 d5391b6095b6e11dd79f86047812a86a 387 SMART SM00897 22 220 7.3E-24 T 13-10-2018 IPR013702 FIST domain, N-terminal Astex_2330 d5391b6095b6e11dd79f86047812a86a 387 SMART SM01204 221 365 2.2E-34 T 13-10-2018 IPR019494 FIST, C-domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 Astex_2330 d5391b6095b6e11dd79f86047812a86a 387 Pfam PF10442 FIST C domain 221 364 8.1E-25 T 13-10-2018 IPR019494 FIST, C-domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 Astex_2330 d5391b6095b6e11dd79f86047812a86a 387 Pfam PF08495 FIST N domain 24 218 2.5E-29 T 13-10-2018 IPR013702 FIST domain, N-terminal Astex_1571 2be69c1887e3e90d0557de5feaa9900f 173 Gene3D G3DSA:2.160.10.10 1 173 1.5E-62 T 13-10-2018 Astex_1571 2be69c1887e3e90d0557de5feaa9900f 173 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 88 121 4.4E-8 T 13-10-2018 IPR001451 Hexapeptide repeat Astex_1571 2be69c1887e3e90d0557de5feaa9900f 173 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 12 44 1.2E-4 T 13-10-2018 IPR001451 Hexapeptide repeat Astex_1571 2be69c1887e3e90d0557de5feaa9900f 173 SUPERFAMILY SSF51161 3 168 9.29E-48 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily Astex_0480 715b206ed4aae5be078c0ec2227d2f4e 191 Pfam PF07310 PAS domain 1 134 2.2E-23 T 13-10-2018 IPR009922 Protein of unknown function DUF1457 Astex_0480 715b206ed4aae5be078c0ec2227d2f4e 191 PIRSF PIRSF031878 1 189 2.7E-24 T 13-10-2018 IPR009922 Protein of unknown function DUF1457 Astex_0918 0727d771a05a4ebf4272cd7a1472cbd1 147 SUPERFAMILY SSF53927 3 141 7.96E-36 T 13-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 Astex_0918 0727d771a05a4ebf4272cd7a1472cbd1 147 Gene3D G3DSA:3.40.140.10 1 145 1.3E-37 T 13-10-2018 Astex_0918 0727d771a05a4ebf4272cd7a1472cbd1 147 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 100 1.9E-17 T 13-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain Astex_2129 daf39d3459c49532caab42eaa16c3275 313 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 49 305 2.0E-31 T 13-10-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system Astex_0114 9bc1665fc053c61e6fb0a0b3467a8e66 141 Pfam PF00011 Hsp20/alpha crystallin family 43 138 6.1E-9 T 13-10-2018 IPR002068 Alpha crystallin/Hsp20 domain Astex_0114 9bc1665fc053c61e6fb0a0b3467a8e66 141 SUPERFAMILY SSF49764 30 138 1.26E-11 T 13-10-2018 IPR008978 HSP20-like chaperone Astex_0114 9bc1665fc053c61e6fb0a0b3467a8e66 141 Gene3D G3DSA:2.60.40.790 31 140 2.5E-12 T 13-10-2018 IPR008978 HSP20-like chaperone Astex_3521 abf00a9fa249d7526374e61470c7acc7 478 SUPERFAMILY SSF111283 38 478 2.09E-111 T 13-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 Astex_3521 abf00a9fa249d7526374e61470c7acc7 478 Gene3D G3DSA:3.30.2290.10 24 256 2.2E-60 T 13-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal Astex_3521 abf00a9fa249d7526374e61470c7acc7 478 Pfam PF01523 Putative modulator of DNA gyrase 56 347 4.6E-54 T 13-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 Astex_1539 e9b18c80e0ae9899787cfc05ebd5c444 145 Gene3D G3DSA:3.30.420.270 67 138 2.4E-16 T 13-10-2018 Astex_1539 e9b18c80e0ae9899787cfc05ebd5c444 145 Pfam PF02472 Biopolymer transport protein ExbD/TolR 18 140 1.1E-29 T 13-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 Astex_0135 0ec3ab1d1809824049a86033095acfcb 169 Gene3D G3DSA:3.30.160.150 28 166 1.2E-37 T 13-10-2018 Astex_1841 7f5c8ae7bea54537de0478367a5029e1 369 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 42 369 1.2E-119 T 13-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Astex_1841 7f5c8ae7bea54537de0478367a5029e1 369 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 72 84 5.1E-5 T 13-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Astex_1841 7f5c8ae7bea54537de0478367a5029e1 369 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 27 367 24.403 T 13-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Astex_1841 7f5c8ae7bea54537de0478367a5029e1 369 ProSitePatterns PS01347 MraY family signature 1. 72 84 - T 13-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Astex_1841 7f5c8ae7bea54537de0478367a5029e1 369 ProSitePatterns PS01348 MraY family signature 2. 198 209 - T 13-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Astex_1841 7f5c8ae7bea54537de0478367a5029e1 369 Pfam PF00953 Glycosyl transferase family 4 103 293 5.3E-34 T 13-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 Astex_2460 a7a3b8babbee71d930a2bebcac795dcc 147 Pfam PF05443 ROS/MUCR transcriptional regulator protein 7 127 2.1E-49 T 13-10-2018 IPR008807 ROSMUCR transcriptional regulator GO:0003677|GO:0006355|GO:0008270 Astex_2460 a7a3b8babbee71d930a2bebcac795dcc 147 Gene3D G3DSA:1.10.10.1550 54 110 2.2E-30 T 13-10-2018 Astex_0758 a12452ad5740f479126d1acff5354afd 141 Gene3D G3DSA:1.20.120.550 11 140 1.0E-14 T 13-10-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamily Astex_0758 a12452ad5740f479126d1acff5354afd 141 Pfam PF01124 MAPEG family 20 135 2.2E-13 T 13-10-2018 IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein Astex_0758 a12452ad5740f479126d1acff5354afd 141 SUPERFAMILY SSF161084 15 133 2.35E-17 T 13-10-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamily Astex_1587 3ae95edc288b1d6d68c19b4b4644dbb5 308 Gene3D G3DSA:1.20.120.1780 189 306 3.3E-15 T 13-10-2018 Astex_1587 3ae95edc288b1d6d68c19b4b4644dbb5 308 TIGRFAM TIGR01474 ubiA_proteo: 4-hydroxybenzoate polyprenyl transferase 25 304 3.2E-100 T 13-10-2018 IPR006370 4-hydroxybenzoate polyprenyltransferase-like GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 Astex_1587 3ae95edc288b1d6d68c19b4b4644dbb5 308 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 85 107 - T 13-10-2018 IPR030470 UbiA prenyltransferase conserved site Astex_1587 3ae95edc288b1d6d68c19b4b4644dbb5 308 Hamap MF_01635 4-hydroxybenzoate octaprenyltransferase [ubiA]. 20 306 25.613 T 13-10-2018 IPR006370 4-hydroxybenzoate polyprenyltransferase-like GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 Astex_1587 3ae95edc288b1d6d68c19b4b4644dbb5 308 Gene3D G3DSA:1.10.357.140 39 188 2.4E-46 T 13-10-2018 Astex_1587 3ae95edc288b1d6d68c19b4b4644dbb5 308 Pfam PF01040 UbiA prenyltransferase family 44 287 2.3E-55 T 13-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 Astex_2774 1d3151c498106999bd9176e8f87fa575 223 Gene3D G3DSA:2.40.160.10 10 221 7.8E-6 T 13-10-2018 IPR023614 Porin domain superfamily Astex_2774 1d3151c498106999bd9176e8f87fa575 223 Pfam PF09694 Bacterial protein of unknown function (Gcw_chp) 22 223 3.8E-33 T 13-10-2018 IPR010239 Conserved hypothetical protein CHP02001 Astex_2774 1d3151c498106999bd9176e8f87fa575 223 TIGRFAM TIGR02001 gcw_chp: conserved hypothetical protein 3 223 2.7E-48 T 13-10-2018 IPR010239 Conserved hypothetical protein CHP02001 Astex_2774 1d3151c498106999bd9176e8f87fa575 223 SUPERFAMILY SSF56935 45 202 1.54E-10 T 13-10-2018 Astex_3708 8aee24a4aa31f4faab86ed0c81de6211 1421 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1117 1193 1.1E-22 T 13-10-2018 IPR022385 Rhs repeat-associated core GO:0097264 Astex_3708 8aee24a4aa31f4faab86ed0c81de6211 1421 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 338 369 1.3E-4 T 13-10-2018 IPR006530 YD repeat Astex_3708 8aee24a4aa31f4faab86ed0c81de6211 1421 Gene3D G3DSA:2.180.10.10 1077 1193 1.2E-28 T 13-10-2018 Astex_2696 1377aa22294ddb607c0e7c20ba80adcb 243 Pfam PF09976 Tetratricopeptide repeat-like domain 28 154 8.1E-14 T 13-10-2018 IPR018704 Tetratricopeptide repeat-like domain Reactome: R-HSA-192823|Reactome: R-HSA-381038|Reactome: R-HSA-381426|Reactome: R-HSA-6798695|Reactome: R-HSA-8957275 Astex_2696 1377aa22294ddb607c0e7c20ba80adcb 243 SUPERFAMILY SSF48452 93 217 1.19E-5 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_2850 8f3a89f27920f8d429f7f48f1943ba0d 400 SUPERFAMILY SSF50156 108 216 7.23E-15 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 Astex_2850 8f3a89f27920f8d429f7f48f1943ba0d 400 Gene3D G3DSA:2.30.42.10 151 233 2.2E-14 T 13-10-2018 Astex_2850 8f3a89f27920f8d429f7f48f1943ba0d 400 Pfam PF02163 Peptidase family M50 11 377 7.2E-66 T 13-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 Astex_0128 be7dad2139c4ae2fa0a5aaeda2d3f15e 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 225 4.1E-21 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Astex_0128 be7dad2139c4ae2fa0a5aaeda2d3f15e 227 Gene3D G3DSA:3.40.50.2300 1 129 4.0E-36 T 13-10-2018 Astex_0128 be7dad2139c4ae2fa0a5aaeda2d3f15e 227 SMART SM00448 4 116 8.2E-39 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_0128 be7dad2139c4ae2fa0a5aaeda2d3f15e 227 SUPERFAMILY SSF52172 3 133 9.53E-38 T 13-10-2018 IPR011006 CheY-like superfamily Astex_0128 be7dad2139c4ae2fa0a5aaeda2d3f15e 227 Pfam PF00072 Response regulator receiver domain 7 117 5.8E-28 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_0128 be7dad2139c4ae2fa0a5aaeda2d3f15e 227 SMART SM00862 150 225 1.7E-20 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Astex_0128 be7dad2139c4ae2fa0a5aaeda2d3f15e 227 SUPERFAMILY SSF46894 126 225 5.95E-19 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Astex_0128 be7dad2139c4ae2fa0a5aaeda2d3f15e 227 Gene3D G3DSA:1.10.10.10 130 227 6.4E-23 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_2083 eb6ad10b87f54a2923a9008251c7940b 129 SUPERFAMILY SSF52091 3 120 7.46E-6 T 13-10-2018 IPR036513 STAS domain superfamily Astex_2083 eb6ad10b87f54a2923a9008251c7940b 129 Gene3D G3DSA:3.40.50.10600 1 119 4.9E-5 T 13-10-2018 IPR038396 SpoIIAA-like superfamily Astex_2506 03ab96f32b8a3ebf8b7d6cd862a3dddf 307 Pfam PF03547 Membrane transport protein 157 298 2.1E-16 T 13-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 Astex_2177 f26deedd29eb2d474add4519b179acd5 569 Pfam PF08811 Protein of unknown function (DUF1800) 52 566 2.5E-90 T 13-10-2018 IPR014917 Protein of unknown function DUF1800 Astex_3393 7f7682ee56940622d98e9aeaa192e6c2 148 Pfam PF04134 Protein of unknown function, DUF393 28 135 2.2E-22 T 13-10-2018 IPR007263 Protein of unknown function DUF393 Astex_2121 ba0d9b749d2aa9f4a90e15537ac50dfc 292 SUPERFAMILY SSF161098 22 292 1.4E-65 T 13-10-2018 IPR035906 MetI-like superfamily Astex_2121 ba0d9b749d2aa9f4a90e15537ac50dfc 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 285 9.1E-15 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Astex_2121 ba0d9b749d2aa9f4a90e15537ac50dfc 292 Gene3D G3DSA:1.10.3720.10 14 283 2.7E-56 T 13-10-2018 IPR035906 MetI-like superfamily Astex_1305 026a21e778a2a0f06307e8a9a07b7c09 488 SUPERFAMILY SSF52266 109 442 5.86E-69 T 13-10-2018 Astex_1305 026a21e778a2a0f06307e8a9a07b7c09 488 Gene3D G3DSA:3.40.50.1110 109 383 7.4E-21 T 13-10-2018 IPR036514 SGNH hydrolase superfamily Astex_1305 026a21e778a2a0f06307e8a9a07b7c09 488 Pfam PF03629 Carbohydrate esterase, sialic acid-specific acetylesterase 111 380 1.6E-19 T 13-10-2018 IPR005181 Sialate O-acetylesterase domain Astex_1409 d49a85cee68daf07068835a49e4b53f1 459 Gene3D G3DSA:3.50.50.60 210 334 2.3E-6 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_1409 d49a85cee68daf07068835a49e4b53f1 459 Pfam PF01593 Flavin containing amine oxidoreductase 24 301 1.3E-18 T 13-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 Astex_1409 d49a85cee68daf07068835a49e4b53f1 459 SUPERFAMILY SSF51905 15 430 1.17E-51 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_1409 d49a85cee68daf07068835a49e4b53f1 459 Gene3D G3DSA:3.50.50.60 10 112 4.8E-16 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_3436 f771c2a8b9bb3d9e432c03f4d4cc72fa 48 Pfam PF03597 Cytochrome oxidase maturation protein cbb3-type 2 45 5.3E-18 T 13-10-2018 IPR004714 Cytochrome oxidase maturation protein cbb3-type Astex_3436 f771c2a8b9bb3d9e432c03f4d4cc72fa 48 TIGRFAM TIGR00847 ccoS: cytochrome oxidase maturation protein, cbb3-type 2 46 5.0E-16 T 13-10-2018 IPR004714 Cytochrome oxidase maturation protein cbb3-type Astex_0278 307e00a674486343817274acec764cde 422 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 353 366 6.3E-22 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Astex_0278 307e00a674486343817274acec764cde 422 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 45 63 6.3E-22 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Astex_0278 307e00a674486343817274acec764cde 422 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 66 78 6.3E-22 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Astex_0278 307e00a674486343817274acec764cde 422 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 171 184 6.3E-22 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Astex_0278 307e00a674486343817274acec764cde 422 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 252 271 6.3E-22 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Astex_0278 307e00a674486343817274acec764cde 422 Gene3D G3DSA:3.20.20.10 41 260 6.3E-79 T 13-10-2018 IPR029066 PLP-binding barrel Astex_0278 307e00a674486343817274acec764cde 422 Gene3D G3DSA:2.40.37.10 261 365 6.3E-79 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Astex_0278 307e00a674486343817274acec764cde 422 SUPERFAMILY SSF51419 19 264 2.91E-46 T 13-10-2018 IPR029066 PLP-binding barrel Astex_0278 307e00a674486343817274acec764cde 422 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 35 262 4.0E-39 T 13-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 Astex_0278 307e00a674486343817274acec764cde 422 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 263 349 4.7E-7 T 13-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 Astex_0278 307e00a674486343817274acec764cde 422 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 45 63 - T 13-10-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site Astex_0278 307e00a674486343817274acec764cde 422 SUPERFAMILY SSF50621 228 380 1.23E-33 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Astex_3632 d6debbfe66e5fc85e9cd0801e88c1d56 362 SUPERFAMILY SSF56601 22 357 5.43E-53 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like Astex_3632 d6debbfe66e5fc85e9cd0801e88c1d56 362 Pfam PF00144 Beta-lactamase 71 280 1.7E-39 T 13-10-2018 IPR001466 Beta-lactamase-related Astex_3632 d6debbfe66e5fc85e9cd0801e88c1d56 362 Gene3D G3DSA:3.40.710.10 29 347 1.4E-53 T 13-10-2018 Astex_2608 bc1732d4f21b0844c4540c4c4ef9512f 314 SUPERFAMILY SSF53474 56 274 3.02E-40 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_2608 bc1732d4f21b0844c4540c4c4ef9512f 314 Gene3D G3DSA:3.40.50.1820 27 289 5.6E-51 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_2608 bc1732d4f21b0844c4540c4c4ef9512f 314 Pfam PF07859 alpha/beta hydrolase fold 85 275 6.7E-17 T 13-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 Astex_2346 81b94dd77fe08c2a20bc7f5ff51e272a 99 Gene3D G3DSA:3.30.1150.10 25 98 2.2E-5 T 13-10-2018 Astex_1748 446a989646f92a709fcc67e0f02bb22c 721 SUPERFAMILY SSF56601 83 443 1.07E-60 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like Astex_1748 446a989646f92a709fcc67e0f02bb22c 721 Pfam PF00144 Beta-lactamase 90 434 1.5E-52 T 13-10-2018 IPR001466 Beta-lactamase-related Astex_1748 446a989646f92a709fcc67e0f02bb22c 721 Gene3D G3DSA:3.40.710.10 82 441 6.7E-65 T 13-10-2018 Astex_0925 f0949bc3be4f7ff4772ad48bc0153079 40 TIGRFAM TIGR02106 cyd_oper_ybgT: cyd operon protein YbgT 1 26 4.1E-14 T 13-10-2018 IPR011724 Cyd operon protein YbgT MetaCyc: PWY-7545 Astex_0925 f0949bc3be4f7ff4772ad48bc0153079 40 Pfam PF08173 Membrane bound YbgT-like protein 1 26 1.7E-14 T 13-10-2018 IPR012994 Membrane bound YbgT-like Astex_2879 fad911fd9ce757f02f126e7b7d72f091 117 Pfam PF06993 Protein of unknown function (DUF1304) 8 113 6.3E-42 T 13-10-2018 IPR009732 Protein of unknown function DUF1304 Astex_0277 0938d9894aa084c0acf80f4195389948 734 SUPERFAMILY SSF141371 641 720 6.28E-6 T 13-10-2018 Astex_0277 0938d9894aa084c0acf80f4195389948 734 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 454 587 5.5E-27 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_0277 0938d9894aa084c0acf80f4195389948 734 SMART SM00283 374 643 7.6E-28 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_0277 0938d9894aa084c0acf80f4195389948 734 SMART SM00304 296 349 0.0029 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Astex_0277 0938d9894aa084c0acf80f4195389948 734 Gene3D G3DSA:1.10.287.950 347 651 1.3E-47 T 13-10-2018 Astex_0277 0938d9894aa084c0acf80f4195389948 734 Gene3D G3DSA:1.10.8.500 297 346 5.0E-5 T 13-10-2018 Astex_0277 0938d9894aa084c0acf80f4195389948 734 SUPERFAMILY SSF58104 324 634 2.09E-49 T 13-10-2018 Astex_0277 0938d9894aa084c0acf80f4195389948 734 Pfam PF07238 PilZ domain 645 722 6.6E-7 T 13-10-2018 IPR009875 PilZ domain GO:0035438 Astex_3482 ecf62bd4a891a1a4916a976ecc19b81b 243 SUPERFAMILY SSF46565 1 56 1.57E-8 T 13-10-2018 IPR036869 Chaperone J-domain superfamily Astex_3482 ecf62bd4a891a1a4916a976ecc19b81b 243 Pfam PF01556 DnaJ C terminal domain 99 222 2.1E-8 T 13-10-2018 IPR002939 Chaperone DnaJ, C-terminal Astex_3482 ecf62bd4a891a1a4916a976ecc19b81b 243 SUPERFAMILY SSF49493 155 226 3.27E-6 T 13-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 Astex_3482 ecf62bd4a891a1a4916a976ecc19b81b 243 Gene3D G3DSA:2.60.260.20 153 242 4.4E-7 T 13-10-2018 Astex_3482 ecf62bd4a891a1a4916a976ecc19b81b 243 Gene3D G3DSA:1.10.287.110 1 58 1.6E-9 T 13-10-2018 IPR036869 Chaperone J-domain superfamily Astex_3423 43ae8626dceb9325a851b51998d87f26 321 PIRSF PIRSF018266 4 320 2.6E-64 T 13-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component Astex_3423 43ae8626dceb9325a851b51998d87f26 321 Gene3D G3DSA:2.60.120.1440 105 239 1.8E-25 T 13-10-2018 Astex_3423 43ae8626dceb9325a851b51998d87f26 321 Pfam PF04773 FecR protein 114 203 3.6E-20 T 13-10-2018 IPR006860 FecR protein Astex_1448 78827563a0cde515689afac73a82b116 312 Gene3D G3DSA:3.40.50.1820 41 311 1.2E-33 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1448 78827563a0cde515689afac73a82b116 312 Pfam PF12697 Alpha/beta hydrolase family 57 305 5.4E-14 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 Astex_1448 78827563a0cde515689afac73a82b116 312 SUPERFAMILY SSF53474 40 311 6.55E-30 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1494 5af403bc2de6a222774b15179386902c 234 Pfam PF03749 Sugar fermentation stimulation protein 13 225 5.8E-66 T 13-10-2018 IPR005224 Sugar fermentation stimulation protein Astex_1494 5af403bc2de6a222774b15179386902c 234 Hamap MF_00095 Sugar fermentation stimulation protein A [sfsA]. 1 234 48.817 T 13-10-2018 IPR005224 Sugar fermentation stimulation protein Astex_1494 5af403bc2de6a222774b15179386902c 234 Gene3D G3DSA:3.40.1350.60 80 233 1.4E-43 T 13-10-2018 Astex_1494 5af403bc2de6a222774b15179386902c 234 Gene3D G3DSA:2.40.50.580 1 79 9.4E-24 T 13-10-2018 Astex_1494 5af403bc2de6a222774b15179386902c 234 TIGRFAM TIGR00230 sfsA: sugar fermentation stimulation protein 5 231 2.8E-60 T 13-10-2018 IPR005224 Sugar fermentation stimulation protein Astex_2221 b5a35ce59b1e70f9bc0874bed37ae691 254 SUPERFAMILY SSF56300 25 253 3.8E-42 T 13-10-2018 Astex_2221 b5a35ce59b1e70f9bc0874bed37ae691 254 Pfam PF00149 Calcineurin-like phosphoesterase 27 217 1.1E-14 T 13-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 Astex_2221 b5a35ce59b1e70f9bc0874bed37ae691 254 Gene3D G3DSA:3.60.21.10 23 254 1.1E-54 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like Astex_1121 594c0ff8645268ccf6be2bb4e635cd58 211 SUPERFAMILY SSF52833 36 204 1.88E-37 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Astex_1121 594c0ff8645268ccf6be2bb4e635cd58 211 Gene3D G3DSA:3.40.30.10 30 210 9.7E-46 T 13-10-2018 Astex_1121 594c0ff8645268ccf6be2bb4e635cd58 211 Pfam PF13462 Thioredoxin 37 205 3.1E-45 T 13-10-2018 IPR012336 Thioredoxin-like fold Astex_2846 d194fe4f3376585e2756ac06f79348f1 185 Gene3D G3DSA:3.30.1360.40 31 105 3.9E-66 T 13-10-2018 Astex_2846 d194fe4f3376585e2756ac06f79348f1 185 SUPERFAMILY SSF55194 5 184 1.7E-68 T 13-10-2018 IPR036191 RRF superfamily Reactome: R-HSA-5419276 Astex_2846 d194fe4f3376585e2756ac06f79348f1 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 25.761 T 13-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 Astex_2846 d194fe4f3376585e2756ac06f79348f1 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 10 185 3.1E-68 T 13-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 Astex_2846 d194fe4f3376585e2756ac06f79348f1 185 Pfam PF01765 Ribosome recycling factor 20 183 1.4E-60 T 13-10-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 Astex_2846 d194fe4f3376585e2756ac06f79348f1 185 Gene3D G3DSA:1.10.132.20 12 182 3.9E-66 T 13-10-2018 Astex_0295 cb421276508b1ef4386a66782443ca35 410 SUPERFAMILY SSF88713 196 408 2.45E-50 T 13-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 Astex_0295 cb421276508b1ef4386a66782443ca35 410 Pfam PF04748 Divergent polysaccharide deacetylase 201 408 1.3E-54 T 13-10-2018 IPR006837 Divergent polysaccharide deacetylase Astex_0295 cb421276508b1ef4386a66782443ca35 410 Gene3D G3DSA:3.20.20.370 182 410 1.8E-68 T 13-10-2018 Astex_1569 6fe6011b17d3296ffe3abc0758b01453 128 Pfam PF13453 Transcription factor zinc-finger 5 44 2.3E-17 T 13-10-2018 IPR027392 Transcription factor zinc-finger Astex_0799 8d32b89dc5affe5cc518e7b0e87b7575 158 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 5 155 6.6E-51 T 13-10-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC Astex_0799 8d32b89dc5affe5cc518e7b0e87b7575 158 Gene3D G3DSA:3.90.960.10 1 157 1.2E-49 T 13-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 Astex_0799 8d32b89dc5affe5cc518e7b0e87b7575 158 Pfam PF04073 Aminoacyl-tRNA editing domain 35 143 8.9E-24 T 13-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 Astex_0799 8d32b89dc5affe5cc518e7b0e87b7575 158 SUPERFAMILY SSF55826 6 155 9.16E-43 T 13-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 Astex_0799 8d32b89dc5affe5cc518e7b0e87b7575 158 PIRSF PIRSF006181 1 158 1.0E-47 T 13-10-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC Astex_2060 45ec12dee990259296ef280f2fe7374e 651 Gene3D G3DSA:1.25.40.10 291 620 3.2E-14 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_2060 45ec12dee990259296ef280f2fe7374e 651 SUPERFAMILY SSF46894 11 103 2.3E-15 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 Astex_2060 45ec12dee990259296ef280f2fe7374e 651 SMART SM00862 28 102 5.4E-11 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Astex_2060 45ec12dee990259296ef280f2fe7374e 651 Gene3D G3DSA:1.10.10.10 8 114 4.0E-20 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_2060 45ec12dee990259296ef280f2fe7374e 651 Pfam PF00486 Transcriptional regulatory protein, C terminal 35 102 9.7E-13 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 Astex_2060 45ec12dee990259296ef280f2fe7374e 651 SUPERFAMILY SSF48452 363 600 1.93E-12 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_0355 657bdc0a1fb8721497a18c17652d2230 176 Pfam PF13031 Protein of unknown function (DUF3892) 11 89 8.7E-15 T 13-10-2018 IPR024997 Protein of unknown function DUF3892 Astex_2714 b8d57d52a94113fec52cdf027b978d4a 169 Pfam PF09832 Uncharacterized protein conserved in bacteria (DUF2059) 92 150 6.2E-16 T 13-10-2018 IPR018637 Domain of unknown function DUF2059 Astex_2120 4ff6941dd4cb26d491c5dac3a9c4a40c 433 Pfam PF13416 Bacterial extracellular solute-binding protein 57 354 4.4E-20 T 13-10-2018 IPR006059 Bacterial extracellular solute-binding protein Astex_2120 4ff6941dd4cb26d491c5dac3a9c4a40c 433 SUPERFAMILY SSF53850 32 428 5.89E-42 T 13-10-2018 Astex_2120 4ff6941dd4cb26d491c5dac3a9c4a40c 433 Gene3D G3DSA:3.40.190.10 144 420 1.1E-119 T 13-10-2018 Astex_2120 4ff6941dd4cb26d491c5dac3a9c4a40c 433 Gene3D G3DSA:3.40.190.10 36 377 1.1E-119 T 13-10-2018 Astex_1250 871fd18f142772304ae3f3e36ad4c50b 101 Pfam PF10135 Rod binding protein 44 92 2.5E-9 T 13-10-2018 IPR019301 Flagellar protein FlgJ, N-terminal Astex_2202 eac8039c1e25992083805e38de1bedef 101 Pfam PF01527 Transposase 11 65 1.4E-14 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 Astex_2202 eac8039c1e25992083805e38de1bedef 101 SUPERFAMILY SSF48295 11 57 2.3E-9 T 13-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 Astex_0646 51635ab3e8fa36e6c26d6fd01c10161d 249 SMART SM00850 156 247 3.5E-10 T 13-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 Astex_0646 51635ab3e8fa36e6c26d6fd01c10161d 249 Pfam PF04397 LytTr DNA-binding domain 160 245 2.8E-15 T 13-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 Astex_0106 fb9c28428c307d8934d6ddb5f513548c 190 Gene3D G3DSA:1.10.10.10 37 140 6.5E-23 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_0106 fb9c28428c307d8934d6ddb5f513548c 190 SUPERFAMILY SSF46785 50 137 1.73E-23 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_0106 fb9c28428c307d8934d6ddb5f513548c 190 Pfam PF03551 Transcriptional regulator PadR-like family 54 124 2.9E-16 T 13-10-2018 IPR005149 Transcription regulator PadR, N-terminal Astex_2354 9504c3f20475c8e2faa1f0112d7e226e 549 Pfam PF08811 Protein of unknown function (DUF1800) 36 546 8.0E-92 T 13-10-2018 IPR014917 Protein of unknown function DUF1800 Astex_0323 ab8b028d846e0c3b2c8b1fdb20b48bd6 389 Gene3D G3DSA:3.90.580.10 6 103 3.7E-8 T 13-10-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 Astex_0323 ab8b028d846e0c3b2c8b1fdb20b48bd6 389 SUPERFAMILY SSF57783 2 99 1.64E-8 T 13-10-2018 Astex_0337 4f2bcaca428c742f462750d8f112ceeb 140 Gene3D G3DSA:3.30.2000.30 2 138 2.4E-24 T 13-10-2018 Astex_0337 4f2bcaca428c742f462750d8f112ceeb 140 Pfam PF11367 Protein of unknown function (DUF3168) 11 133 8.0E-29 T 13-10-2018 IPR021508 Tail completion protein Astex_3461 52f16d5abbd3c3858527c46c136883a6 658 SUPERFAMILY SSF55120 104 275 5.4E-34 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 Astex_3461 52f16d5abbd3c3858527c46c136883a6 658 Pfam PF01479 S4 domain 46 92 3.7E-11 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_3461 52f16d5abbd3c3858527c46c136883a6 658 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 144 158 - T 13-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 Astex_3461 52f16d5abbd3c3858527c46c136883a6 658 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 111 273 2.0E-38 T 13-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 Astex_3461 52f16d5abbd3c3858527c46c136883a6 658 Pfam PF00849 RNA pseudouridylate synthase 110 242 3.4E-10 T 13-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 Astex_3461 52f16d5abbd3c3858527c46c136883a6 658 SMART SM00363 46 104 1.6E-10 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_3461 52f16d5abbd3c3858527c46c136883a6 658 Gene3D G3DSA:3.10.290.10 43 101 1.9E-17 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 Astex_3461 52f16d5abbd3c3858527c46c136883a6 658 Gene3D G3DSA:3.30.70.1560 168 263 1.0E-48 T 13-10-2018 Astex_3461 52f16d5abbd3c3858527c46c136883a6 658 SUPERFAMILY SSF55174 44 103 1.45E-12 T 13-10-2018 Astex_3461 52f16d5abbd3c3858527c46c136883a6 658 Gene3D G3DSA:3.30.70.580 110 270 1.0E-48 T 13-10-2018 Astex_2703 c081343a808147e5c4ff3d5d4ba47e3d 165 Pfam PF02674 Colicin V production protein 5 141 5.6E-24 T 13-10-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 Astex_0923 3cee9bfdcc427382c3fd9ecc959ca086 529 PIRSF PIRSF006446 1 521 2.2E-139 T 13-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 Astex_0923 3cee9bfdcc427382c3fd9ecc959ca086 529 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 8 502 3.7E-171 T 13-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 Astex_2067 a702e731db0f9f6a90fb47f122466031 243 Gene3D G3DSA:1.20.1290.10 7 240 1.6E-50 T 13-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 Astex_2067 a702e731db0f9f6a90fb47f122466031 243 Pfam PF02627 Carboxymuconolactone decarboxylase family 34 104 3.2E-13 T 13-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 Astex_2067 a702e731db0f9f6a90fb47f122466031 243 Pfam PF02627 Carboxymuconolactone decarboxylase family 151 233 3.6E-14 T 13-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 Astex_2067 a702e731db0f9f6a90fb47f122466031 243 SUPERFAMILY SSF69118 11 187 8.64E-33 T 13-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 Astex_3559 2c32dff3ba84fb627dc47bd21b7687cf 430 Pfam PF13635 Domain of unknown function (DUF4143) 208 368 2.5E-22 T 13-10-2018 IPR025420 Domain of unknown function DUF4143 Astex_3559 2c32dff3ba84fb627dc47bd21b7687cf 430 SUPERFAMILY SSF52540 15 214 1.9E-12 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_3559 2c32dff3ba84fb627dc47bd21b7687cf 430 Pfam PF13173 AAA domain 23 142 8.5E-22 T 13-10-2018 Astex_3580 9798def353b4d4edcd2c7231286b667d 336 Pfam PF02653 Branched-chain amino acid transport system / permease component 55 323 2.8E-50 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 Astex_0719 4c32ad0ca8afc0e1bf1246062e6cd46f 497 Gene3D G3DSA:1.25.40.10 340 496 6.1E-46 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_0719 4c32ad0ca8afc0e1bf1246062e6cd46f 497 SUPERFAMILY SSF48452 168 284 3.25E-5 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_0719 4c32ad0ca8afc0e1bf1246062e6cd46f 497 Gene3D G3DSA:1.25.40.10 162 339 8.9E-41 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_0719 4c32ad0ca8afc0e1bf1246062e6cd46f 497 SMART SM00671 323 359 2.0E-6 T 13-10-2018 IPR006597 Sel1-like repeat Astex_0719 4c32ad0ca8afc0e1bf1246062e6cd46f 497 SMART SM00671 360 395 2.6E-7 T 13-10-2018 IPR006597 Sel1-like repeat Astex_0719 4c32ad0ca8afc0e1bf1246062e6cd46f 497 SMART SM00671 251 286 4.2E-9 T 13-10-2018 IPR006597 Sel1-like repeat Astex_0719 4c32ad0ca8afc0e1bf1246062e6cd46f 497 SMART SM00671 432 467 4.9E-6 T 13-10-2018 IPR006597 Sel1-like repeat Astex_0719 4c32ad0ca8afc0e1bf1246062e6cd46f 497 SMART SM00671 396 431 5.7E-4 T 13-10-2018 IPR006597 Sel1-like repeat Astex_0719 4c32ad0ca8afc0e1bf1246062e6cd46f 497 SMART SM00671 196 231 6.0E-6 T 13-10-2018 IPR006597 Sel1-like repeat Astex_0719 4c32ad0ca8afc0e1bf1246062e6cd46f 497 SMART SM00671 287 322 1.8E-6 T 13-10-2018 IPR006597 Sel1-like repeat Astex_0719 4c32ad0ca8afc0e1bf1246062e6cd46f 497 SUPERFAMILY SSF81901 253 474 7.85E-48 T 13-10-2018 Astex_0719 4c32ad0ca8afc0e1bf1246062e6cd46f 497 Pfam PF08238 Sel1 repeat 323 359 4.9E-7 T 13-10-2018 IPR006597 Sel1-like repeat Astex_0719 4c32ad0ca8afc0e1bf1246062e6cd46f 497 Pfam PF08238 Sel1 repeat 432 459 0.0033 T 13-10-2018 IPR006597 Sel1-like repeat Astex_0719 4c32ad0ca8afc0e1bf1246062e6cd46f 497 Pfam PF08238 Sel1 repeat 197 229 4.6E-5 T 13-10-2018 IPR006597 Sel1-like repeat Astex_0719 4c32ad0ca8afc0e1bf1246062e6cd46f 497 Pfam PF08238 Sel1 repeat 361 391 2.2E-4 T 13-10-2018 IPR006597 Sel1-like repeat Astex_0719 4c32ad0ca8afc0e1bf1246062e6cd46f 497 Pfam PF08238 Sel1 repeat 396 430 1.2E-4 T 13-10-2018 IPR006597 Sel1-like repeat Astex_0719 4c32ad0ca8afc0e1bf1246062e6cd46f 497 Pfam PF08238 Sel1 repeat 294 319 0.0029 T 13-10-2018 IPR006597 Sel1-like repeat Astex_0719 4c32ad0ca8afc0e1bf1246062e6cd46f 497 Pfam PF08238 Sel1 repeat 252 283 1.9E-8 T 13-10-2018 IPR006597 Sel1-like repeat Astex_0580 4f62b3a370b462b9cdc46fca966f884e 342 SUPERFAMILY SSF53756 11 322 5.14E-59 T 13-10-2018 Astex_0580 4f62b3a370b462b9cdc46fca966f884e 342 Gene3D G3DSA:3.40.50.2000 1 155 4.2E-6 T 13-10-2018 Astex_0580 4f62b3a370b462b9cdc46fca966f884e 342 Gene3D G3DSA:3.40.50.2000 157 319 7.7E-44 T 13-10-2018 Astex_0580 4f62b3a370b462b9cdc46fca966f884e 342 Pfam PF00534 Glycosyl transferases group 1 156 304 4.1E-36 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 Astex_2604 b01205ace765b0c1bb32dce6af307a25 143 Gene3D G3DSA:3.30.300.20 5 139 2.6E-32 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta Astex_2604 b01205ace765b0c1bb32dce6af307a25 143 SUPERFAMILY SSF82784 9 136 3.14E-32 T 13-10-2018 IPR036102 OsmC/Ohr superfamily Astex_2604 b01205ace765b0c1bb32dce6af307a25 143 Pfam PF02566 OsmC-like protein 41 135 8.7E-16 T 13-10-2018 IPR003718 OsmC/Ohr family Astex_1051 3870c97a9c22ba114ecde11cd318fc0f 465 Pfam PF03929 PepSY-associated TM region 23 400 7.1E-67 T 13-10-2018 IPR005625 PepSY-associated TM protein Astex_2153 8822af8f137e54fc1c1c5d8114d31842 415 Pfam PF13657 HipA N-terminal domain 14 120 4.8E-18 T 13-10-2018 IPR017508 HipA, N-terminal subdomain 1 Astex_2153 8822af8f137e54fc1c1c5d8114d31842 415 Pfam PF07804 HipA-like C-terminal domain 142 384 3.2E-50 T 13-10-2018 IPR012893 HipA-like, C-terminal Astex_2153 8822af8f137e54fc1c1c5d8114d31842 415 TIGRFAM TIGR03071 couple_hipA: HipA N-terminal domain 14 120 3.7E-12 T 13-10-2018 IPR017508 HipA, N-terminal subdomain 1 Astex_2828 e64a67f791f5ab6a092c8e3e2033f600 240 SUPERFAMILY SSF141523 55 170 3.66E-9 T 13-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like Astex_2911 6a4eb8ae0adaa49305a58e28077b06df 325 SUPERFAMILY SSF102114 45 308 1.03E-61 T 13-10-2018 Astex_2911 6a4eb8ae0adaa49305a58e28077b06df 325 Pfam PF04055 Radical SAM superfamily 86 245 4.7E-15 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 Astex_2911 6a4eb8ae0adaa49305a58e28077b06df 325 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 22 68 9.5E-7 T 13-10-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 Astex_2911 6a4eb8ae0adaa49305a58e28077b06df 325 Hamap MF_00206 Lipoyl synthase [lipA]. 1 317 147.31 T 13-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 Astex_2911 6a4eb8ae0adaa49305a58e28077b06df 325 Gene3D G3DSA:3.20.20.70 76 295 1.2E-17 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_2911 6a4eb8ae0adaa49305a58e28077b06df 325 PIRSF PIRSF005963 3 325 4.4E-132 T 13-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 Astex_2911 6a4eb8ae0adaa49305a58e28077b06df 325 TIGRFAM TIGR00510 lipA: lipoyl synthase 23 311 7.5E-112 T 13-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 Astex_2911 6a4eb8ae0adaa49305a58e28077b06df 325 SMART SM00729 79 287 6.9E-13 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 Astex_0338 d935f42f4312238b7a97d911f0001527 155 Pfam PF06199 Phage tail tube protein 7 145 9.5E-15 T 13-10-2018 IPR011855 Phage major tail protein TP901-1 Astex_0358 3857bd004cf8ba16762611c81d1ff5e0 283 Gene3D G3DSA:3.40.50.150 16 241 1.5E-40 T 13-10-2018 Astex_0358 3857bd004cf8ba16762611c81d1ff5e0 283 Pfam PF02086 D12 class N6 adenine-specific DNA methyltransferase 20 196 1.2E-23 T 13-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 Astex_0358 3857bd004cf8ba16762611c81d1ff5e0 283 PIRSF PIRSF000398 11 268 6.4E-42 T 13-10-2018 IPR012263 Adenine modification methylase, M.EcoRV-type GO:0009007|GO:0032775 Astex_0358 3857bd004cf8ba16762611c81d1ff5e0 283 SUPERFAMILY SSF53335 15 265 2.46E-54 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Astex_0358 3857bd004cf8ba16762611c81d1ff5e0 283 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 64 77 5.6E-12 T 13-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 Astex_0358 3857bd004cf8ba16762611c81d1ff5e0 283 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 43 57 5.6E-12 T 13-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 Astex_0358 3857bd004cf8ba16762611c81d1ff5e0 283 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 185 197 5.6E-12 T 13-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 Astex_0358 3857bd004cf8ba16762611c81d1ff5e0 283 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 20 36 5.6E-12 T 13-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 Astex_0358 3857bd004cf8ba16762611c81d1ff5e0 283 Gene3D G3DSA:1.10.1020.10 71 165 1.5E-40 T 13-10-2018 IPR023095 Adenine-specific methyltransferase, domain 2 GO:0009007 Astex_3172 ad481c94ba4d3fe08178d20cc58dd149 150 Pfam PF05433 Glycine zipper 2TM domain 47 87 7.0E-11 T 13-10-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 Astex_1974 36890a0135917ba050609490e5717ea4 232 Pfam PF01323 DSBA-like thioredoxin domain 9 208 7.3E-42 T 13-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 Astex_1974 36890a0135917ba050609490e5717ea4 232 SUPERFAMILY SSF52833 5 213 1.24E-42 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Astex_1974 36890a0135917ba050609490e5717ea4 232 Gene3D G3DSA:3.40.30.10 1 212 5.7E-70 T 13-10-2018 Astex_0167 d6a2c15787489f74d61af9d54e1fcdb0 319 SUPERFAMILY SSF52540 110 277 1.61E-33 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0167 d6a2c15787489f74d61af9d54e1fcdb0 319 Pfam PF02562 PhoH-like protein 111 314 7.6E-86 T 13-10-2018 IPR003714 PhoH-like protein GO:0005524 Astex_0167 d6a2c15787489f74d61af9d54e1fcdb0 319 Gene3D G3DSA:3.40.50.300 108 314 5.6E-71 T 13-10-2018 Astex_2622 2ed913dca1306144b1b5f87166136a76 228 Pfam PF02104 SURF1 family 15 205 1.5E-26 T 13-10-2018 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_1809 53f69b65b9c5f7bab0d5459531ec1752 365 PIRSF PIRSF000183 1 365 4.7E-150 T 13-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 Astex_1809 53f69b65b9c5f7bab0d5459531ec1752 365 SUPERFAMILY SSF52283 1 359 1.79E-64 T 13-10-2018 Astex_1809 53f69b65b9c5f7bab0d5459531ec1752 365 Gene3D G3DSA:3.40.50.720 130 305 1.2E-136 T 13-10-2018 Astex_1809 53f69b65b9c5f7bab0d5459531ec1752 365 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 364 5.8E-148 T 13-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 Astex_1809 53f69b65b9c5f7bab0d5459531ec1752 365 Gene3D G3DSA:3.40.50.720 3 352 1.2E-136 T 13-10-2018 Astex_1809 53f69b65b9c5f7bab0d5459531ec1752 365 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 5 137 6.6E-46 T 13-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal Astex_1809 53f69b65b9c5f7bab0d5459531ec1752 365 SMART SM01002 149 297 4.9E-84 T 13-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain Astex_1809 53f69b65b9c5f7bab0d5459531ec1752 365 SUPERFAMILY SSF51735 137 303 3.23E-47 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_1809 53f69b65b9c5f7bab0d5459531ec1752 365 SMART SM01003 4 137 7.0E-74 T 13-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal Astex_1809 53f69b65b9c5f7bab0d5459531ec1752 365 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 142 352 5.3E-79 T 13-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain Astex_0826 7f2c91015d23ca6299bd71a9d64241c1 372 Gene3D G3DSA:2.40.50.940 222 288 3.3E-10 T 13-10-2018 Astex_0826 7f2c91015d23ca6299bd71a9d64241c1 372 Gene3D G3DSA:2.40.50.140 289 362 3.3E-10 T 13-10-2018 Astex_0826 7f2c91015d23ca6299bd71a9d64241c1 372 SMART SM00382 32 216 9.2E-20 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_0826 7f2c91015d23ca6299bd71a9d64241c1 372 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Astex_0826 7f2c91015d23ca6299bd71a9d64241c1 372 Pfam PF08402 TOBE domain 283 366 2.7E-15 T 13-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 Astex_0826 7f2c91015d23ca6299bd71a9d64241c1 372 Gene3D G3DSA:3.40.50.300 5 220 8.3E-69 T 13-10-2018 Astex_0826 7f2c91015d23ca6299bd71a9d64241c1 372 SUPERFAMILY SSF50331 241 365 8.84E-12 T 13-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal Astex_0826 7f2c91015d23ca6299bd71a9d64241c1 372 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 38 363 1.3E-117 T 13-10-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 Astex_0826 7f2c91015d23ca6299bd71a9d64241c1 372 SUPERFAMILY SSF52540 7 245 3.47E-88 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0826 7f2c91015d23ca6299bd71a9d64241c1 372 Pfam PF00005 ABC transporter 23 165 4.3E-37 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_0927 c3d707201d70dec1610024675a654f4c 83 Gene3D G3DSA:3.10.20.30 2 83 1.6E-15 T 13-10-2018 IPR012675 Beta-grasp domain superfamily Astex_0927 c3d707201d70dec1610024675a654f4c 83 Pfam PF02597 ThiS family 5 83 8.5E-11 T 13-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 Astex_0927 c3d707201d70dec1610024675a654f4c 83 SUPERFAMILY SSF54285 2 83 2.06E-12 T 13-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp Astex_1756 0af2bc00b275ad8a15e937806f749724 317 Gene3D G3DSA:2.160.20.120 171 317 1.3E-18 T 13-10-2018 Astex_1729 173615532343c09dbe4d34bf01045c71 484 SUPERFAMILY SSF53590 37 177 1.36E-7 T 13-10-2018 IPR036452 Ribonucleoside hydrolase-like Astex_1729 173615532343c09dbe4d34bf01045c71 484 Gene3D G3DSA:2.60.40.10 370 483 4.1E-25 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_1729 173615532343c09dbe4d34bf01045c71 484 Pfam PF07632 Protein of unknown function (DUF1593) 38 305 4.6E-100 T 13-10-2018 IPR011483 Protein of unknown function DUF1593 Astex_1729 173615532343c09dbe4d34bf01045c71 484 Gene3D G3DSA:3.90.245.10 35 369 6.9E-122 T 13-10-2018 IPR036452 Ribonucleoside hydrolase-like Astex_2163 14e7dda1b8235135e931fc9ca90d581e 447 Gene3D G3DSA:1.25.40.10 126 316 1.6E-23 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_2163 14e7dda1b8235135e931fc9ca90d581e 447 SUPERFAMILY SSF48452 148 314 1.36E-16 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_3747 acecfc9939ee1a6788b6eaadb49ad91d 1047 SUPERFAMILY SSF55464 1 341 2.47E-61 T 13-10-2018 Astex_3747 acecfc9939ee1a6788b6eaadb49ad91d 1047 SUPERFAMILY SSF52540 612 945 6.37E-13 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_3747 acecfc9939ee1a6788b6eaadb49ad91d 1047 SUPERFAMILY SSF52540 479 627 8.38E-16 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_3747 acecfc9939ee1a6788b6eaadb49ad91d 1047 Gene3D G3DSA:3.40.50.300 441 659 9.6E-28 T 13-10-2018 Astex_3747 acecfc9939ee1a6788b6eaadb49ad91d 1047 Pfam PF08751 TrwC relaxase 13 322 8.1E-79 T 13-10-2018 IPR014862 TrwC relaxase Astex_3747 acecfc9939ee1a6788b6eaadb49ad91d 1047 TIGRFAM TIGR02686 relax_trwC: conjugative relaxase domain 14 326 1.6E-52 T 13-10-2018 IPR014059 Conjugative relaxase, N-terminal Astex_3747 acecfc9939ee1a6788b6eaadb49ad91d 1047 Pfam PF13604 AAA domain 484 672 4.7E-35 T 13-10-2018 Astex_1699 4ff8d97afb6483de897d30e94bf9af93 187 Gene3D G3DSA:3.30.1330.60 40 187 7.1E-35 T 13-10-2018 IPR036737 OmpA-like domain superfamily Astex_1699 4ff8d97afb6483de897d30e94bf9af93 187 PRINTS PR01021 OMPA domain signature 130 146 7.7E-11 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 Astex_1699 4ff8d97afb6483de897d30e94bf9af93 187 PRINTS PR01021 OMPA domain signature 84 106 7.7E-11 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 Astex_1699 4ff8d97afb6483de897d30e94bf9af93 187 PRINTS PR01021 OMPA domain signature 115 130 7.7E-11 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 Astex_1699 4ff8d97afb6483de897d30e94bf9af93 187 Pfam PF00691 OmpA family 84 179 1.0E-18 T 13-10-2018 IPR006665 OmpA-like domain Astex_1699 4ff8d97afb6483de897d30e94bf9af93 187 SUPERFAMILY SSF103088 76 185 1.29E-32 T 13-10-2018 IPR036737 OmpA-like domain superfamily Astex_2118 77ade727e1fde077912c522b1f1efa4c 392 SUPERFAMILY SSF48208 35 387 4.95E-56 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 Astex_2118 77ade727e1fde077912c522b1f1efa4c 392 Pfam PF07470 Glycosyl Hydrolase Family 88 53 387 5.8E-70 T 13-10-2018 IPR010905 Glycosyl hydrolase, family 88 Astex_2118 77ade727e1fde077912c522b1f1efa4c 392 Gene3D G3DSA:1.50.10.10 43 386 6.2E-105 T 13-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 Astex_2543 d772446f53b5b0cbc31081f54b270f59 234 Gene3D G3DSA:1.10.357.10 25 200 5.6E-13 T 13-10-2018 Astex_2543 d772446f53b5b0cbc31081f54b270f59 234 TIGRFAM TIGR02396 diverge_rpsU: rpsU-divergently transcribed protein 36 210 1.1E-21 T 13-10-2018 IPR012762 Ubiquinone biosynthesis protein COQ9 GO:0006744 Reactome: R-HSA-2142789 Astex_2543 d772446f53b5b0cbc31081f54b270f59 234 Pfam PF08511 COQ9 133 205 8.5E-14 T 13-10-2018 IPR013718 COQ9 Reactome: R-HSA-2142789 Astex_1743 4521d7cbf14e63285fdfc3efebfcf707 281 Pfam PF12729 Four helix bundle sensory module for signal transduction 1 160 8.3E-11 T 13-10-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain Astex_1743 4521d7cbf14e63285fdfc3efebfcf707 281 Gene3D G3DSA:1.20.1480.50 164 263 4.3E-9 T 13-10-2018 Astex_1743 4521d7cbf14e63285fdfc3efebfcf707 281 SMART SM00304 205 259 6.5E-4 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Astex_1034 c3bdc97d6890a2edfa0b00880842d222 704 Pfam PF00593 TonB dependent receptor 239 703 2.9E-59 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_1034 c3bdc97d6890a2edfa0b00880842d222 704 Gene3D G3DSA:2.40.170.20 177 703 8.6E-117 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_1034 c3bdc97d6890a2edfa0b00880842d222 704 Pfam PF07715 TonB-dependent Receptor Plug Domain 65 165 5.2E-14 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_1034 c3bdc97d6890a2edfa0b00880842d222 704 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 66 702 1.4E-90 T 13-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 Astex_1034 c3bdc97d6890a2edfa0b00880842d222 704 SUPERFAMILY SSF56935 32 703 5.0E-125 T 13-10-2018 Astex_1034 c3bdc97d6890a2edfa0b00880842d222 704 Gene3D G3DSA:2.170.130.10 49 176 1.6E-23 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_1696 e5983313de73649d29ae614b91ebbe04 423 Gene3D G3DSA:1.20.1250.20 11 230 2.0E-38 T 13-10-2018 Astex_1696 e5983313de73649d29ae614b91ebbe04 423 TIGRFAM TIGR01272 gluP: glucose/galactose transporter WARNING 96 412 1.1E-98 T 13-10-2018 IPR005964 Bacterial glucose/galactose transporter GO:0005354|GO:0005355|GO:0015757|GO:0016021|GO:1904659 Astex_1696 e5983313de73649d29ae614b91ebbe04 423 Gene3D G3DSA:1.20.1250.20 233 422 7.0E-41 T 13-10-2018 Astex_1696 e5983313de73649d29ae614b91ebbe04 423 Pfam PF07690 Major Facilitator Superfamily 20 379 2.1E-12 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Astex_1696 e5983313de73649d29ae614b91ebbe04 423 SUPERFAMILY SSF103473 12 418 1.96E-27 T 13-10-2018 IPR036259 MFS transporter superfamily Astex_0974 2b2d456b391e9d7c5b410b15fc56593c 424 Gene3D G3DSA:1.20.1250.20 9 403 7.0E-68 T 13-10-2018 Astex_0974 2b2d456b391e9d7c5b410b15fc56593c 424 SUPERFAMILY SSF103473 12 407 5.62E-65 T 13-10-2018 IPR036259 MFS transporter superfamily Astex_0974 2b2d456b391e9d7c5b410b15fc56593c 424 PRINTS PR01035 Tetracycline resistance protein signature 51 70 5.3E-54 T 13-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Astex_0974 2b2d456b391e9d7c5b410b15fc56593c 424 PRINTS PR01035 Tetracycline resistance protein signature 82 106 5.3E-54 T 13-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Astex_0974 2b2d456b391e9d7c5b410b15fc56593c 424 PRINTS PR01035 Tetracycline resistance protein signature 139 161 5.3E-54 T 13-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Astex_0974 2b2d456b391e9d7c5b410b15fc56593c 424 PRINTS PR01035 Tetracycline resistance protein signature 283 304 5.3E-54 T 13-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Astex_0974 2b2d456b391e9d7c5b410b15fc56593c 424 PRINTS PR01035 Tetracycline resistance protein signature 21 37 5.3E-54 T 13-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Astex_0974 2b2d456b391e9d7c5b410b15fc56593c 424 PRINTS PR01035 Tetracycline resistance protein signature 167 187 5.3E-54 T 13-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Astex_0974 2b2d456b391e9d7c5b410b15fc56593c 424 PRINTS PR01035 Tetracycline resistance protein signature 109 130 5.3E-54 T 13-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Astex_0974 2b2d456b391e9d7c5b410b15fc56593c 424 PRINTS PR01035 Tetracycline resistance protein signature 343 366 5.3E-54 T 13-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Astex_0974 2b2d456b391e9d7c5b410b15fc56593c 424 PRINTS PR01035 Tetracycline resistance protein signature 255 275 5.3E-54 T 13-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Astex_0974 2b2d456b391e9d7c5b410b15fc56593c 424 Pfam PF07690 Major Facilitator Superfamily 15 359 5.0E-46 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Astex_2937 dea4899318116c720bb45e7c5535a6e9 177 SUPERFAMILY SSF48013 32 175 1.03E-33 T 13-10-2018 IPR035926 NusB-like superfamily Astex_2937 dea4899318116c720bb45e7c5535a6e9 177 Pfam PF01029 NusB family 36 174 4.0E-30 T 13-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 Astex_2937 dea4899318116c720bb45e7c5535a6e9 177 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 33 175 4.5E-38 T 13-10-2018 IPR011605 NusB antitermination factor GO:0006353 Astex_2937 dea4899318116c720bb45e7c5535a6e9 177 Gene3D G3DSA:1.10.940.10 29 177 3.7E-38 T 13-10-2018 IPR035926 NusB-like superfamily Astex_2937 dea4899318116c720bb45e7c5535a6e9 177 Hamap MF_00073 Transcription antitermination protein NusB [nusB]. 31 177 21.231 T 13-10-2018 IPR011605 NusB antitermination factor GO:0006353 Astex_3817 3093f5bf4d36cce5704112ab38fbbb0c 992 Pfam PF01526 Tn3 transposase DDE domain 586 972 1.8E-127 T 13-10-2018 IPR002513 Tn3 transposase DDE domain GO:0004803|GO:0006313 Astex_3817 3093f5bf4d36cce5704112ab38fbbb0c 992 Pfam PF13700 Domain of unknown function (DUF4158) 6 169 3.3E-44 T 13-10-2018 IPR025296 Domain of unknown function DUF4158 Astex_3843 79fd9e1e1517ef1a95e552d0e5749197 123 Pfam PF11604 Copper binding periplasmic protein CusF 55 121 2.3E-26 T 13-10-2018 IPR021647 Copper binding periplasmic protein CusF Astex_3843 79fd9e1e1517ef1a95e552d0e5749197 123 Gene3D G3DSA:2.40.50.320 50 123 1.3E-27 T 13-10-2018 Astex_2233 afaa6037cc58ca287238d2f00139d7c9 313 PIRSF PIRSF018266 6 313 5.9E-37 T 13-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component Astex_2233 afaa6037cc58ca287238d2f00139d7c9 313 Pfam PF16220 Domain of unknown function (DUF4880) 14 50 6.2E-8 T 13-10-2018 IPR032623 FecR, N-terminal Astex_3384 e8400c69218e258d2e10a2f803506166 502 Gene3D G3DSA:3.50.50.60 1 494 5.4E-179 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_3384 e8400c69218e258d2e10a2f803506166 502 Pfam PF04820 Tryptophan halogenase 6 462 1.6E-177 T 13-10-2018 IPR006905 Flavin-dependent halogenase Astex_3384 e8400c69218e258d2e10a2f803506166 502 PIRSF PIRSF011396 1 499 8.3E-183 T 13-10-2018 IPR033856 Flavin-dependent tryptophan halogenase Astex_3384 e8400c69218e258d2e10a2f803506166 502 SUPERFAMILY SSF51905 5 423 8.03E-28 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily Astex_1722 e839aab12f1e8d242d33d2aad9f88f2d 369 Gene3D G3DSA:1.20.1420.30 69 359 3.7E-8 T 13-10-2018 Astex_1722 e839aab12f1e8d242d33d2aad9f88f2d 369 Gene3D G3DSA:1.20.58.1130 43 257 3.7E-8 T 13-10-2018 Astex_1722 e839aab12f1e8d242d33d2aad9f88f2d 369 Pfam PF01699 Sodium/calcium exchanger protein 225 367 8.5E-14 T 13-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 Astex_1722 e839aab12f1e8d242d33d2aad9f88f2d 369 Pfam PF01699 Sodium/calcium exchanger protein 40 193 8.2E-17 T 13-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 Astex_2025 84e72d6b345ec4e3bbab479a7a900cf9 361 PIRSF PIRSF035865 1 361 1.6E-84 T 13-10-2018 IPR014598 Uncharacterised conserved protein UCP035865 Astex_2025 84e72d6b345ec4e3bbab479a7a900cf9 361 Pfam PF10098 Uncharacterised protein conserved in bacteria (DUF2336) 90 349 2.0E-65 T 13-10-2018 IPR019285 Protein of unknown function DUF2336 Astex_0449 780154e4390310144e8f27b778475326 147 Pfam PF09851 Short C-terminal domain 117 143 3.7E-7 T 13-10-2018 IPR018649 SHOCT domain Astex_0449 780154e4390310144e8f27b778475326 147 Pfam PF05154 TM2 domain 15 66 4.5E-13 T 13-10-2018 IPR007829 TM2 domain Astex_3831 1dcdacb75f13241c3f3d40ff88c0e496 366 Pfam PF01757 Acyltransferase family 16 342 3.1E-26 T 13-10-2018 IPR002656 Acyltransferase 3 GO:0016747 Astex_3624 d039f5ef7da45237b017df66345048ae 119 SUPERFAMILY SSF54909 1 114 4.47E-29 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel Astex_3624 d039f5ef7da45237b017df66345048ae 119 Gene3D G3DSA:3.30.70.1060 1 114 8.0E-34 T 13-10-2018 Astex_3624 d039f5ef7da45237b017df66345048ae 119 Pfam PF03795 YCII-related domain 1 112 6.5E-15 T 13-10-2018 IPR005545 YCII-related Astex_3158 e7e021a213a36a5c82a03fa0ee6e486d 255 Pfam PF01522 Polysaccharide deacetylase 36 154 6.9E-17 T 13-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 Astex_3158 e7e021a213a36a5c82a03fa0ee6e486d 255 Gene3D G3DSA:3.20.20.370 37 253 1.3E-26 T 13-10-2018 Astex_3158 e7e021a213a36a5c82a03fa0ee6e486d 255 SUPERFAMILY SSF88713 33 250 4.45E-27 T 13-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 Astex_0446 45aebe7d891b075ab2bb7498e8547fe4 112 Gene3D G3DSA:3.40.1440.10 19 111 5.2E-13 T 13-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 Astex_0446 45aebe7d891b075ab2bb7498e8547fe4 112 SUPERFAMILY SSF82771 21 87 1.16E-6 T 13-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 Astex_0547 11d3a6e0022c3888ab2a3a350d21a8e7 142 Pfam PF07681 DoxX 20 96 3.1E-11 T 13-10-2018 IPR032808 DoxX family Astex_2229 e60a080e8c8b5ee055c51233ddcd76fe 209 Pfam PF13471 Transglutaminase-like superfamily 92 207 1.1E-25 T 13-10-2018 IPR032708 Microcin J25-processing protein McjB, C-terminal Astex_0227 cdd3c426a42a0e5b3c6bf3a7a4c2b190 177 Gene3D G3DSA:3.30.530.20 23 177 8.3E-20 T 13-10-2018 IPR023393 START-like domain superfamily Astex_0227 cdd3c426a42a0e5b3c6bf3a7a4c2b190 177 SUPERFAMILY SSF55961 25 176 5.77E-18 T 13-10-2018 Astex_0227 cdd3c426a42a0e5b3c6bf3a7a4c2b190 177 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 27 174 2.8E-17 T 13-10-2018 IPR019587 Polyketide cyclase/dehydrase Astex_2722 c05c3c204a4833f35b9b63f7566ecc87 888 Pfam PF00593 TonB dependent receptor 417 887 3.6E-35 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_2722 c05c3c204a4833f35b9b63f7566ecc87 888 Pfam PF07715 TonB-dependent Receptor Plug Domain 49 160 3.9E-15 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_2722 c05c3c204a4833f35b9b63f7566ecc87 888 Gene3D G3DSA:2.40.170.20 276 888 1.9E-51 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_2722 c05c3c204a4833f35b9b63f7566ecc87 888 Gene3D G3DSA:2.170.130.10 33 164 3.7E-14 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_2722 c05c3c204a4833f35b9b63f7566ecc87 888 SUPERFAMILY SSF56935 32 886 1.61E-88 T 13-10-2018 Astex_2722 c05c3c204a4833f35b9b63f7566ecc87 888 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 31 887 5.5E-186 T 13-10-2018 IPR010104 Bacterial TonB-dependent receptor Astex_0842 d400e0ac3493a5d9c3ce5a9c15f591a1 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 221 2.4E-51 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0842 d400e0ac3493a5d9c3ce5a9c15f591a1 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 2.4E-51 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0842 d400e0ac3493a5d9c3ce5a9c15f591a1 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 2.4E-51 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0842 d400e0ac3493a5d9c3ce5a9c15f591a1 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 2.4E-51 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0842 d400e0ac3493a5d9c3ce5a9c15f591a1 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 2.4E-51 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0842 d400e0ac3493a5d9c3ce5a9c15f591a1 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 2.4E-51 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0842 d400e0ac3493a5d9c3ce5a9c15f591a1 241 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 178 0.0014 T 13-10-2018 Astex_0842 d400e0ac3493a5d9c3ce5a9c15f591a1 241 Gene3D G3DSA:3.40.50.720 1 240 1.2E-81 T 13-10-2018 Astex_0842 d400e0ac3493a5d9c3ce5a9c15f591a1 241 SUPERFAMILY SSF51735 3 239 2.86E-84 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_0842 d400e0ac3493a5d9c3ce5a9c15f591a1 241 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Astex_0842 d400e0ac3493a5d9c3ce5a9c15f591a1 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 3.3E-15 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0842 d400e0ac3493a5d9c3ce5a9c15f591a1 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 3.3E-15 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0842 d400e0ac3493a5d9c3ce5a9c15f591a1 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 3.3E-15 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_0842 d400e0ac3493a5d9c3ce5a9c15f591a1 241 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 238 1.4E-66 T 13-10-2018 Astex_0842 d400e0ac3493a5d9c3ce5a9c15f591a1 241 TIGRFAM TIGR01829 AcAcCoA_reduct: acetoacetyl-CoA reductase 3 239 1.6E-110 T 13-10-2018 IPR011283 Acetoacetyl-CoA reductase GO:0005737|GO:0018454|GO:0042619|GO:0055114 KEGG: 00630+1.1.1.36|KEGG: 00650+1.1.1.36|MetaCyc: PWY-5676|MetaCyc: PWY-5741|MetaCyc: PWY-7216|MetaCyc: PWY-7948 Astex_2161 2b454eb8a3a2729246453f4fa5d5cde1 442 Pfam PF07804 HipA-like C-terminal domain 151 352 2.5E-34 T 13-10-2018 IPR012893 HipA-like, C-terminal Astex_2161 2b454eb8a3a2729246453f4fa5d5cde1 442 Pfam PF13657 HipA N-terminal domain 3 102 1.0E-21 T 13-10-2018 IPR017508 HipA, N-terminal subdomain 1 Astex_2161 2b454eb8a3a2729246453f4fa5d5cde1 442 TIGRFAM TIGR03071 couple_hipA: HipA N-terminal domain 3 102 1.1E-25 T 13-10-2018 IPR017508 HipA, N-terminal subdomain 1 Astex_1475 27960e6fdc9258d4c35f66a03d308aef 308 SUPERFAMILY SSF81301 34 156 1.85E-12 T 13-10-2018 Astex_1475 27960e6fdc9258d4c35f66a03d308aef 308 Gene3D G3DSA:3.30.460.10 23 151 8.7E-15 T 13-10-2018 Astex_1475 27960e6fdc9258d4c35f66a03d308aef 308 Pfam PF05168 HEPN domain 178 286 2.2E-8 T 13-10-2018 IPR007842 HEPN domain Astex_1475 27960e6fdc9258d4c35f66a03d308aef 308 SUPERFAMILY SSF81593 180 293 1.02E-7 T 13-10-2018 Astex_1475 27960e6fdc9258d4c35f66a03d308aef 308 Pfam PF01909 Nucleotidyltransferase domain 44 101 1.1E-5 T 13-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 Astex_1475 27960e6fdc9258d4c35f66a03d308aef 308 SMART SM00748 184 302 8.6E-5 T 13-10-2018 IPR007842 HEPN domain Astex_1475 27960e6fdc9258d4c35f66a03d308aef 308 Gene3D G3DSA:1.20.120.330 165 308 4.7E-47 T 13-10-2018 Astex_2235 a42a453e5de052f22ddb06d6673f15c3 644 Gene3D G3DSA:3.40.50.300 268 508 9.0E-37 T 13-10-2018 Astex_2235 a42a453e5de052f22ddb06d6673f15c3 644 SUPERFAMILY SSF52540 68 508 4.25E-50 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2235 a42a453e5de052f22ddb06d6673f15c3 644 Pfam PF02534 Type IV secretory system Conjugative DNA transfer 70 518 5.2E-100 T 13-10-2018 IPR003688 Type IV secretion system protein TraG/VirD4 GO:0009291|GO:0016020 Astex_3847 5632dc52c49f53a7a193e2b44c83bffa 91 Pfam PF02583 Metal-sensitive transcriptional repressor 9 89 8.9E-24 T 13-10-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 Astex_3847 5632dc52c49f53a7a193e2b44c83bffa 91 Gene3D G3DSA:1.20.58.1000 4 91 9.5E-25 T 13-10-2018 IPR038390 Metal-sensitive transcriptional repressor superfamily Astex_3320 2b519dc209b80befc46e36f0d842bb50 405 ProSitePatterns PS00591 Glycosyl hydrolases family 10 (GH10) active site. 293 303 - T 13-10-2018 IPR031158 Glycosyl hydrolases family 10, active site MetaCyc: PWY-6717|MetaCyc: PWY-6784 Astex_3320 2b519dc209b80befc46e36f0d842bb50 405 PRINTS PR00134 Glycosyl hydrolase family 10 signature 231 242 2.0E-15 T 13-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 Astex_3320 2b519dc209b80befc46e36f0d842bb50 405 PRINTS PR00134 Glycosyl hydrolase family 10 signature 259 271 2.0E-15 T 13-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 Astex_3320 2b519dc209b80befc46e36f0d842bb50 405 PRINTS PR00134 Glycosyl hydrolase family 10 signature 185 196 2.0E-15 T 13-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 Astex_3320 2b519dc209b80befc46e36f0d842bb50 405 PRINTS PR00134 Glycosyl hydrolase family 10 signature 137 149 2.0E-15 T 13-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 Astex_3320 2b519dc209b80befc46e36f0d842bb50 405 Gene3D G3DSA:3.20.20.80 60 403 1.4E-109 T 13-10-2018 Astex_3320 2b519dc209b80befc46e36f0d842bb50 405 SMART SM00633 106 402 6.1E-97 T 13-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 Astex_3320 2b519dc209b80befc46e36f0d842bb50 405 Pfam PF00331 Glycosyl hydrolase family 10 65 400 1.7E-93 T 13-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 Astex_3320 2b519dc209b80befc46e36f0d842bb50 405 SUPERFAMILY SSF51445 61 401 1.21E-93 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_3085 4ef58e6cd401782a3536a6123f81a8f2 172 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 30 171 1.6E-31 T 13-10-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 Astex_3085 4ef58e6cd401782a3536a6123f81a8f2 172 ProSitePatterns PS00332 Copper/Zinc superoxide dismutase signature 2. 160 171 - T 13-10-2018 IPR018152 Superoxide dismutase, copper/zinc, binding site GO:0004784|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 Astex_3085 4ef58e6cd401782a3536a6123f81a8f2 172 Gene3D G3DSA:2.60.40.200 19 172 1.1E-39 T 13-10-2018 IPR036423 Superoxide dismutase-like, copper/zinc binding domain superfamily GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 Astex_3085 4ef58e6cd401782a3536a6123f81a8f2 172 SUPERFAMILY SSF49329 26 171 6.41E-36 T 13-10-2018 IPR036423 Superoxide dismutase-like, copper/zinc binding domain superfamily GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 Astex_3429 8b84b10ea4a426a8f40b67578417db16 753 SUPERFAMILY SSF56935 33 753 2.85E-115 T 13-10-2018 Astex_3429 8b84b10ea4a426a8f40b67578417db16 753 Pfam PF07715 TonB-dependent Receptor Plug Domain 55 164 2.8E-16 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_3429 8b84b10ea4a426a8f40b67578417db16 753 Gene3D G3DSA:2.40.170.20 46 753 5.6E-146 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_3429 8b84b10ea4a426a8f40b67578417db16 753 Pfam PF00593 TonB dependent receptor 275 752 8.7E-48 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_2340 32a5bc2851129ea9fc9abbc9e00327ec 454 SUPERFAMILY SSF53098 156 412 1.67E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily Astex_2340 32a5bc2851129ea9fc9abbc9e00327ec 454 Pfam PF13701 Transposase DDE domain group 1 12 453 9.6E-161 T 13-10-2018 IPR025668 Transposase DDE domain Astex_0926 e84b2a6480c41267d24ed719f8a47eba 401 Gene3D G3DSA:3.40.50.720 56 383 4.6E-102 T 13-10-2018 Astex_0926 e84b2a6480c41267d24ed719f8a47eba 401 Pfam PF02719 Polysaccharide biosynthesis protein 61 337 5.3E-100 T 13-10-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain Astex_0926 e84b2a6480c41267d24ed719f8a47eba 401 SUPERFAMILY SSF51735 58 337 4.92E-54 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_3044 8323872feb525824cd161b751d726953 584 Gene3D G3DSA:1.20.140.10 279 438 3.0E-96 T 13-10-2018 Astex_3044 8323872feb525824cd161b751d726953 584 SUPERFAMILY SSF56645 37 272 5.37E-56 T 13-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 Astex_3044 8323872feb525824cd161b751d726953 584 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 161 268 8.9E-13 T 13-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 Astex_3044 8323872feb525824cd161b751d726953 584 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 457 580 7.8E-24 T 13-10-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain Astex_3044 8323872feb525824cd161b751d726953 584 Gene3D G3DSA:1.10.540.10 47 158 3.0E-96 T 13-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 Astex_3044 8323872feb525824cd161b751d726953 584 Gene3D G3DSA:2.40.110.10 159 278 3.0E-96 T 13-10-2018 Astex_3044 8323872feb525824cd161b751d726953 584 SUPERFAMILY SSF47203 278 447 1.45E-45 T 13-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 Astex_3044 8323872feb525824cd161b751d726953 584 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 39 156 2.1E-12 T 13-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 Astex_3044 8323872feb525824cd161b751d726953 584 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 280 440 4.7E-27 T 13-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 Astex_3849 440abfc944d3b4a6972247a7fc708736 365 Pfam PF01757 Acyltransferase family 8 333 1.8E-19 T 13-10-2018 IPR002656 Acyltransferase 3 GO:0016747 Astex_1905 908ece884dcc49aad2d245ad7c7eff80 245 Gene3D G3DSA:3.40.50.720 1 244 3.9E-77 T 13-10-2018 Astex_1905 908ece884dcc49aad2d245ad7c7eff80 245 SUPERFAMILY SSF51735 1 244 2.01E-72 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_1905 908ece884dcc49aad2d245ad7c7eff80 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 2.2E-38 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1905 908ece884dcc49aad2d245ad7c7eff80 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 2.2E-38 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1905 908ece884dcc49aad2d245ad7c7eff80 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 2.2E-38 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1905 908ece884dcc49aad2d245ad7c7eff80 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.2E-38 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1905 908ece884dcc49aad2d245ad7c7eff80 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 2.2E-38 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1905 908ece884dcc49aad2d245ad7c7eff80 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 2.2E-38 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1905 908ece884dcc49aad2d245ad7c7eff80 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 Astex_1905 908ece884dcc49aad2d245ad7c7eff80 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 243 2.9E-59 T 13-10-2018 Astex_1905 908ece884dcc49aad2d245ad7c7eff80 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 134 3.6E-10 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1905 908ece884dcc49aad2d245ad7c7eff80 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 3.6E-10 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1905 908ece884dcc49aad2d245ad7c7eff80 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 3.6E-10 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR Astex_1180 f6e4f1742828238ff594e013e5fe5f9b 136 Pfam PF05656 Protein of unknown function (DUF805) 12 127 5.1E-15 T 13-10-2018 IPR008523 Protein of unknown function DUF805 GO:0016021 Astex_1010 27b2ba3388caca3e30e3826a1596936c 268 Pfam PF11769 Protein of unknown function (DUF3313) 14 201 3.2E-30 T 13-10-2018 IPR021747 Protein of unknown function DUF3313 Astex_1206 605d1e4a068c2bcc5794f55a08d40ee0 444 Gene3D G3DSA:3.30.2290.10 5 219 3.0E-15 T 13-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal Astex_1206 605d1e4a068c2bcc5794f55a08d40ee0 444 SUPERFAMILY SSF111283 8 438 3.27E-91 T 13-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 Astex_1206 605d1e4a068c2bcc5794f55a08d40ee0 444 Pfam PF01523 Putative modulator of DNA gyrase 25 309 1.8E-53 T 13-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 Astex_0224 febaae89d04e8de781f541e5d6352138 240 Gene3D G3DSA:3.30.2010.10 141 230 1.1E-13 T 13-10-2018 Astex_0224 febaae89d04e8de781f541e5d6352138 240 Pfam PF01863 Protein of unknown function DUF45 33 230 5.0E-45 T 13-10-2018 IPR002725 Protein of unknown function DUF45 Astex_2181 1206243aa21bf08838bce1855c7294b0 208 Pfam PF02397 Bacterial sugar transferase 18 202 2.2E-64 T 13-10-2018 IPR003362 Bacterial sugar transferase Astex_2181 1206243aa21bf08838bce1855c7294b0 208 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 17 208 1.3E-91 T 13-10-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase Astex_1161 e3df60f048db069d887e4ba9fdb5dc75 905 Gene3D G3DSA:2.170.130.10 24 163 6.3E-10 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_1161 e3df60f048db069d887e4ba9fdb5dc75 905 SUPERFAMILY SSF56935 35 905 2.64E-71 T 13-10-2018 Astex_1161 e3df60f048db069d887e4ba9fdb5dc75 905 Pfam PF07715 TonB-dependent Receptor Plug Domain 56 157 5.5E-9 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_1161 e3df60f048db069d887e4ba9fdb5dc75 905 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 35 905 1.6E-165 T 13-10-2018 IPR010104 Bacterial TonB-dependent receptor Astex_1161 e3df60f048db069d887e4ba9fdb5dc75 905 Pfam PF00593 TonB dependent receptor 457 887 6.2E-25 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_1981 e814a7c6b8fdc4fbd806a29749d4c84b 295 Pfam PF00135 Carboxylesterase family 68 178 7.8E-5 T 13-10-2018 IPR002018 Carboxylesterase, type B Astex_1981 e814a7c6b8fdc4fbd806a29749d4c84b 295 SUPERFAMILY SSF53474 67 271 5.46E-22 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1981 e814a7c6b8fdc4fbd806a29749d4c84b 295 Gene3D G3DSA:3.40.50.1820 59 289 2.9E-29 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1903 574b0874430de3067ff997ff6823bf94 102 Gene3D G3DSA:3.90.1210.30 7 88 1.5E-27 T 13-10-2018 Astex_1903 574b0874430de3067ff997ff6823bf94 102 Pfam PF08666 SAF domain 14 83 1.2E-7 T 13-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 Astex_1903 574b0874430de3067ff997ff6823bf94 102 SMART SM00858 14 85 4.9E-8 T 13-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 Astex_2122 d7c369a968601600434f117d0c640546 299 Gene3D G3DSA:1.10.3720.10 48 287 2.7E-68 T 13-10-2018 IPR035906 MetI-like superfamily Astex_2122 d7c369a968601600434f117d0c640546 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 285 7.1E-17 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 Astex_2122 d7c369a968601600434f117d0c640546 299 SUPERFAMILY SSF161098 52 277 3.53E-58 T 13-10-2018 IPR035906 MetI-like superfamily Astex_1486 b4445fac57c33871ae4d0e4031e4a6c3 139 SMART SM01022 5 99 4.5E-5 T 13-10-2018 IPR007374 ASCH domain Astex_1486 b4445fac57c33871ae4d0e4031e4a6c3 139 SUPERFAMILY SSF88697 1 122 1.54E-22 T 13-10-2018 IPR015947 PUA-like superfamily Astex_0785 d9b4753ed748b2b2d451de8d418eacea 140 SUPERFAMILY SSF55486 10 127 9.78E-29 T 13-10-2018 Astex_0785 d9b4753ed748b2b2d451de8d418eacea 140 Gene3D G3DSA:3.30.2010.20 11 128 7.3E-26 T 13-10-2018 IPR038555 Zincin-like metallopeptidase superfamily Astex_0785 d9b4753ed748b2b2d451de8d418eacea 140 Pfam PF06262 Zincin-like metallopeptidase 34 127 4.6E-30 T 13-10-2018 IPR010428 Zincin-like metallopeptidase Astex_0989 306a7f171f4da6aba6d1ca90d2a70ad8 310 Gene3D G3DSA:3.40.710.10 28 300 5.5E-78 T 13-10-2018 Astex_0989 306a7f171f4da6aba6d1ca90d2a70ad8 310 SUPERFAMILY SSF56601 29 296 3.52E-66 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like Astex_0989 306a7f171f4da6aba6d1ca90d2a70ad8 310 Pfam PF13354 Beta-lactamase enzyme family 65 262 4.9E-45 T 13-10-2018 Astex_0989 306a7f171f4da6aba6d1ca90d2a70ad8 310 PRINTS PR00118 Beta-lactamase class A signature 150 174 3.8E-34 T 13-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 Astex_0989 306a7f171f4da6aba6d1ca90d2a70ad8 310 PRINTS PR00118 Beta-lactamase class A signature 114 139 3.8E-34 T 13-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 Astex_0989 306a7f171f4da6aba6d1ca90d2a70ad8 310 PRINTS PR00118 Beta-lactamase class A signature 32 56 3.8E-34 T 13-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 Astex_0989 306a7f171f4da6aba6d1ca90d2a70ad8 310 PRINTS PR00118 Beta-lactamase class A signature 176 201 3.8E-34 T 13-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 Astex_0989 306a7f171f4da6aba6d1ca90d2a70ad8 310 PRINTS PR00118 Beta-lactamase class A signature 212 227 3.8E-34 T 13-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 Astex_0989 306a7f171f4da6aba6d1ca90d2a70ad8 310 PRINTS PR00118 Beta-lactamase class A signature 229 244 3.8E-34 T 13-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 Astex_3203 e7b8f081370eaa836c12ff02c47807db 510 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 7 469 1.4E-156 T 13-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 Astex_3203 e7b8f081370eaa836c12ff02c47807db 510 SUPERFAMILY SSF143968 337 501 3.4E-67 T 13-10-2018 Astex_3203 e7b8f081370eaa836c12ff02c47807db 510 SUPERFAMILY SSF50475 4 336 7.85E-114 T 13-10-2018 Astex_3203 e7b8f081370eaa836c12ff02c47807db 510 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 11 445 7.1E-164 T 13-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 Astex_3203 e7b8f081370eaa836c12ff02c47807db 510 Gene3D G3DSA:1.20.5.570 469 508 4.5E-5 T 13-10-2018 Astex_3203 e7b8f081370eaa836c12ff02c47807db 510 Gene3D G3DSA:3.40.1670.10 351 468 1.4E-51 T 13-10-2018 Astex_3210 92a436deb14614a7a7e10dd26432e72d 529 Pfam PF01120 Alpha-L-fucosidase 53 417 5.3E-97 T 13-10-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 Astex_3210 92a436deb14614a7a7e10dd26432e72d 529 PIRSF PIRSF001092 44 514 1.5E-75 T 13-10-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 Astex_3210 92a436deb14614a7a7e10dd26432e72d 529 SUPERFAMILY SSF51445 57 420 1.33E-86 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_3210 92a436deb14614a7a7e10dd26432e72d 529 Gene3D G3DSA:2.60.40.1180 421 529 3.8E-27 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta Astex_3210 92a436deb14614a7a7e10dd26432e72d 529 Gene3D G3DSA:3.20.20.80 53 420 1.1E-106 T 13-10-2018 Astex_3210 92a436deb14614a7a7e10dd26432e72d 529 SMART SM00812 57 477 1.3E-146 T 13-10-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 Astex_3609 30c4d7642d0884e0c9aeff42f6012f8b 1037 Gene3D G3DSA:2.170.130.10 37 175 4.7E-9 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_3609 30c4d7642d0884e0c9aeff42f6012f8b 1037 Pfam PF00593 TonB dependent receptor 497 1035 2.4E-27 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_3609 30c4d7642d0884e0c9aeff42f6012f8b 1037 Pfam PF07715 TonB-dependent Receptor Plug Domain 70 162 3.7E-9 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_3609 30c4d7642d0884e0c9aeff42f6012f8b 1037 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 44 1037 7.6E-167 T 13-10-2018 IPR010104 Bacterial TonB-dependent receptor Astex_3609 30c4d7642d0884e0c9aeff42f6012f8b 1037 SUPERFAMILY SSF56935 45 1037 1.71E-59 T 13-10-2018 Astex_3114 04bb523a439d3682a7c383b999413405 203 Gene3D G3DSA:1.10.3210.10 9 202 2.6E-56 T 13-10-2018 Astex_3114 04bb523a439d3682a7c383b999413405 203 SUPERFAMILY SSF109604 13 199 6.28E-54 T 13-10-2018 Astex_3420 4050713542b096abefd267d3877743a6 372 Gene3D G3DSA:2.160.20.10 31 365 5.6E-86 T 13-10-2018 IPR012334 Pectin lyase fold Astex_3420 4050713542b096abefd267d3877743a6 372 Pfam PF01095 Pectinesterase 41 274 6.9E-23 T 13-10-2018 IPR000070 Pectinesterase, catalytic GO:0005618|GO:0030599|GO:0042545 KEGG: 00040+3.1.1.11|MetaCyc: PWY-1081|MetaCyc: PWY-7246|MetaCyc: PWY-7248 Astex_3420 4050713542b096abefd267d3877743a6 372 SUPERFAMILY SSF51126 40 346 4.12E-48 T 13-10-2018 IPR011050 Pectin lyase fold/virulence factor Astex_3030 0d5985591c2bd0f543e216f8c6cdba49 985 Pfam PF04453 Organic solvent tolerance protein 512 874 1.2E-34 T 13-10-2018 IPR007543 Organic solvent tolerance protein, C-terminal GO:0010033|GO:0019867|GO:0061024 Astex_3030 0d5985591c2bd0f543e216f8c6cdba49 985 Hamap MF_01411 LPS-assembly protein LptD [lptD]. 10 976 14.456 T 13-10-2018 IPR020889 LPS-assembly protein LptD GO:0009279|GO:0010033|GO:0015920|GO:0043165 Astex_2686 192ffd77b9f0cc88156627680087a928 430 Pfam PF13795 HupE / UreJ protein 196 356 3.8E-43 T 13-10-2018 IPR032809 Putative HupE/UreJ protein Astex_0978 c0a10fb61912cda23006101c214f035f 189 Gene3D G3DSA:1.20.1260.10 18 164 3.9E-6 T 13-10-2018 IPR012347 Ferritin-like Astex_0978 c0a10fb61912cda23006101c214f035f 189 SUPERFAMILY SSF47240 22 157 1.05E-17 T 13-10-2018 IPR009078 Ferritin-like superfamily Astex_0978 c0a10fb61912cda23006101c214f035f 189 Hamap MF_01658 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase [coq7]. 1 189 27.274 T 13-10-2018 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 Reactome: R-HSA-2142789 Astex_0978 c0a10fb61912cda23006101c214f035f 189 Pfam PF03232 Ubiquinone biosynthesis protein COQ7 22 189 1.1E-64 T 13-10-2018 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 Reactome: R-HSA-2142789 Astex_3484 5f78f3e333d4b6b78dd976a5d9b67082 206 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 154 174 9.8E-5 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Astex_3484 5f78f3e333d4b6b78dd976a5d9b67082 206 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 12 23 9.8E-5 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Astex_3484 5f78f3e333d4b6b78dd976a5d9b67082 206 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 136 152 9.8E-5 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Astex_3484 5f78f3e333d4b6b78dd976a5d9b67082 206 Pfam PF13419 Haloacid dehalogenase-like hydrolase 15 189 1.2E-23 T 13-10-2018 Astex_3484 5f78f3e333d4b6b78dd976a5d9b67082 206 Gene3D G3DSA:1.10.150.240 25 95 5.0E-38 T 13-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 Astex_3484 5f78f3e333d4b6b78dd976a5d9b67082 206 SUPERFAMILY SSF56784 13 198 7.11E-42 T 13-10-2018 IPR036412 HAD-like superfamily Astex_3484 5f78f3e333d4b6b78dd976a5d9b67082 206 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 127 188 2.9E-12 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Astex_3484 5f78f3e333d4b6b78dd976a5d9b67082 206 Gene3D G3DSA:3.40.50.1000 13 190 5.0E-38 T 13-10-2018 IPR023214 HAD superfamily Astex_2308 a45f60da55668c8f063f1b3f917801fc 167 SUPERFAMILY SSF54534 31 165 1.37E-43 T 13-10-2018 Astex_2308 a45f60da55668c8f063f1b3f917801fc 167 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 77 163 4.2E-24 T 13-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain Astex_2308 a45f60da55668c8f063f1b3f917801fc 167 Pfam PF01346 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase 27 66 7.6E-8 T 13-10-2018 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 Astex_2308 a45f60da55668c8f063f1b3f917801fc 167 Gene3D G3DSA:3.10.50.40 27 167 3.9E-45 T 13-10-2018 Astex_1020 8f68f658b9704d1cfa35ff374cc68121 386 Pfam PF00108 Thiolase, N-terminal domain 5 224 4.7E-20 T 13-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 Astex_1020 8f68f658b9704d1cfa35ff374cc68121 386 Pfam PF02803 Thiolase, C-terminal domain 257 357 1.3E-9 T 13-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 Astex_1020 8f68f658b9704d1cfa35ff374cc68121 386 Gene3D G3DSA:3.40.47.10 3 384 9.4E-101 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 Astex_1020 8f68f658b9704d1cfa35ff374cc68121 386 PIRSF PIRSF000429 1 384 8.5E-60 T 13-10-2018 IPR002155 Thiolase GO:0016747 Astex_1020 8f68f658b9704d1cfa35ff374cc68121 386 SUPERFAMILY SSF53901 7 380 1.01E-38 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 Astex_1792 6cd210a03959b9f3bb2a6eb5cb993ada 451 Gene3D G3DSA:3.40.640.10 85 338 2.6E-116 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Astex_1792 6cd210a03959b9f3bb2a6eb5cb993ada 451 Pfam PF00202 Aminotransferase class-III 46 419 3.0E-41 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 Astex_1792 6cd210a03959b9f3bb2a6eb5cb993ada 451 SUPERFAMILY SSF53383 19 442 8.29E-81 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Astex_1792 6cd210a03959b9f3bb2a6eb5cb993ada 451 Gene3D G3DSA:3.90.1150.10 18 434 2.6E-116 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Astex_0426 c70df48f0fbf3329bdaf6061a5a5ecd4 57 Pfam PF04964 Flp/Fap pilin component 7 51 8.9E-10 T 13-10-2018 IPR007047 Flp/Fap pilin component Astex_3812 7f409185a43c6acf41ceb69ff47e995f 280 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 8 104 2.7E-7 T 13-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 Astex_3812 7f409185a43c6acf41ceb69ff47e995f 280 SUPERFAMILY SSF52402 5 176 2.14E-20 T 13-10-2018 Astex_3812 7f409185a43c6acf41ceb69ff47e995f 280 Gene3D G3DSA:3.40.50.620 1 188 8.6E-26 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Astex_1074 5326b76883e80a70ea24d8dcbc64fee4 155 SUPERFAMILY SSF46785 43 153 1.28E-33 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_1074 5326b76883e80a70ea24d8dcbc64fee4 155 Gene3D G3DSA:1.10.10.10 34 155 9.8E-43 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1074 5326b76883e80a70ea24d8dcbc64fee4 155 Pfam PF01638 HxlR-like helix-turn-helix 57 143 2.5E-29 T 13-10-2018 IPR002577 Helix-turn-helix, HxlR type Astex_1676 6067c816918726193338d8dee71e3aa6 375 Gene3D G3DSA:3.40.50.620 1 187 1.5E-36 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Astex_1676 6067c816918726193338d8dee71e3aa6 375 SUPERFAMILY SSF52402 2 168 3.91E-30 T 13-10-2018 Astex_1676 6067c816918726193338d8dee71e3aa6 375 Pfam PF01171 PP-loop family 3 167 2.7E-29 T 13-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 Astex_1633 b7b6df10aacbb949d9a18e0bcc2e5ba5 377 Gene3D G3DSA:2.40.10.340 127 201 1.5E-10 T 13-10-2018 Astex_1633 b7b6df10aacbb949d9a18e0bcc2e5ba5 377 Pfam PF04085 rod shape-determining protein MreC 137 252 3.7E-24 T 13-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 Astex_1633 b7b6df10aacbb949d9a18e0bcc2e5ba5 377 Gene3D G3DSA:2.40.10.350 219 255 3.5E-6 T 13-10-2018 Astex_3137 ae8728b7a774465b381a8e23d0fd1c32 183 Pfam PF10691 Protein of unknown function (DUF2497) 112 179 5.7E-22 T 13-10-2018 IPR019632 Protein of unknown function DUF2497 Astex_0341 1ba5a43e089927c6f723bc38ba39fc0e 983 TIGRFAM TIGR02675 tape_meas_nterm: tape measure domain 160 234 9.8E-12 T 13-10-2018 IPR013491 Caudovirus, tape measure, N-terminal Astex_0028 4a4cd91d49a33510c3690104bbdaa6ee 80 SUPERFAMILY SSF47598 2 68 8.53E-18 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 Astex_0028 4a4cd91d49a33510c3690104bbdaa6ee 80 Gene3D G3DSA:1.10.1220.10 10 54 2.1E-13 T 13-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 Astex_2251 443467487cef1a339d8bb77814be53e7 208 PIRSF PIRSF033239 2 198 8.2E-47 T 13-10-2018 IPR010331 Exopolysaccharide synthesis, ExoD Astex_2251 443467487cef1a339d8bb77814be53e7 208 Pfam PF06055 Exopolysaccharide synthesis, ExoD 6 183 2.1E-50 T 13-10-2018 IPR010331 Exopolysaccharide synthesis, ExoD Astex_2143 0bfd1c37ed5ae3d0a6bdf245e78419a0 368 Pfam PF13193 AMP-binding enzyme C-terminal domain 290 362 3.4E-6 T 13-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain Astex_2143 0bfd1c37ed5ae3d0a6bdf245e78419a0 368 SUPERFAMILY SSF56801 82 366 3.14E-50 T 13-10-2018 Astex_2143 0bfd1c37ed5ae3d0a6bdf245e78419a0 368 Pfam PF00501 AMP-binding enzyme 84 273 7.6E-20 T 13-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Astex_2143 0bfd1c37ed5ae3d0a6bdf245e78419a0 368 Gene3D G3DSA:3.40.50.12780 20 275 7.6E-24 T 13-10-2018 Astex_2143 0bfd1c37ed5ae3d0a6bdf245e78419a0 368 Gene3D G3DSA:3.30.300.30 277 368 3.2E-12 T 13-10-2018 Astex_2082 e17c8094a6428224246a291d00d6fb64 321 SUPERFAMILY SSF51735 6 262 4.03E-53 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_2082 e17c8094a6428224246a291d00d6fb64 321 Pfam PF13460 NAD(P)H-binding 13 208 7.4E-19 T 13-10-2018 IPR016040 NAD(P)-binding domain Astex_2082 e17c8094a6428224246a291d00d6fb64 321 Gene3D G3DSA:3.40.50.720 7 260 4.5E-53 T 13-10-2018 Astex_2971 6deb086ddf48e7ebcb800e40ae76f6b5 158 Hamap MF_00023 SsrA-binding protein [smpB]. 1 158 70.551 T 13-10-2018 IPR000037 SsrA-binding protein GO:0003723 Astex_2971 6deb086ddf48e7ebcb800e40ae76f6b5 158 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 12 137 5.0E-50 T 13-10-2018 IPR000037 SsrA-binding protein GO:0003723 Astex_2971 6deb086ddf48e7ebcb800e40ae76f6b5 158 Gene3D G3DSA:2.40.280.10 4 134 1.0E-48 T 13-10-2018 IPR023620 Small protein B Astex_2971 6deb086ddf48e7ebcb800e40ae76f6b5 158 TIGRFAM TIGR00086 smpB: SsrA-binding protein 11 155 7.6E-55 T 13-10-2018 IPR000037 SsrA-binding protein GO:0003723 Astex_2971 6deb086ddf48e7ebcb800e40ae76f6b5 158 ProSitePatterns PS01317 SsrA-binding protein. 30 42 - T 13-10-2018 IPR020081 SsrA-binding protein, conserved site Astex_2971 6deb086ddf48e7ebcb800e40ae76f6b5 158 SUPERFAMILY SSF74982 5 137 8.76E-50 T 13-10-2018 IPR023620 Small protein B Astex_2971 6deb086ddf48e7ebcb800e40ae76f6b5 158 Pfam PF01668 SmpB protein 12 155 2.7E-59 T 13-10-2018 IPR000037 SsrA-binding protein GO:0003723 Astex_1406 3b0974b39bc14fdfa37bb8942e18988b 139 Pfam PF09945 Predicted membrane protein (DUF2177) 3 131 1.4E-39 T 13-10-2018 IPR018687 Protein of unknown function DUF2177, membrane Astex_1222 e09690374c08d62fb4f88d14871b95d8 281 Pfam PF03783 Curli production assembly/transport component CsgG 116 263 1.7E-11 T 13-10-2018 IPR005534 Curli production assembly/transport component CsgG GO:0030288 Astex_1222 e09690374c08d62fb4f88d14871b95d8 281 Gene3D G3DSA:3.40.50.10610 118 271 2.1E-16 T 13-10-2018 Astex_0863 253fa8690953408d7d334882ab95dd60 166 Pfam PF00583 Acetyltransferase (GNAT) family 52 139 5.7E-13 T 13-10-2018 IPR000182 GNAT domain Astex_0863 253fa8690953408d7d334882ab95dd60 166 SUPERFAMILY SSF55729 1 165 1.72E-33 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Astex_0863 253fa8690953408d7d334882ab95dd60 166 Gene3D G3DSA:3.40.630.30 1 163 7.0E-33 T 13-10-2018 Astex_2945 a9d918b19c15e615178e29da18fd1fa4 99 Gene3D G3DSA:3.30.2310.20 2 94 9.9E-10 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Astex_2945 a9d918b19c15e615178e29da18fd1fa4 99 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 7 92 4.7E-9 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family Astex_2184 f3e6e4a072a205211d6be7bb366bc326 406 Pfam PF07786 Protein of unknown function (DUF1624) 11 160 6.6E-5 T 13-10-2018 IPR012429 Domain of unknown function DUF1624 Reactome: R-HSA-2024096|Reactome: R-HSA-2206291|Reactome: R-HSA-6798695 Astex_2184 f3e6e4a072a205211d6be7bb366bc326 406 Pfam PF04235 Protein of unknown function (DUF418) 226 386 1.8E-33 T 13-10-2018 IPR007349 Domain of unknown function DUF418 Astex_1707 0b94e82d97c872a828236e52ffac3761 645 Gene3D G3DSA:2.60.120.260 247 397 4.5E-12 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_1707 0b94e82d97c872a828236e52ffac3761 645 SUPERFAMILY SSF52266 104 588 1.1E-60 T 13-10-2018 Astex_1707 0b94e82d97c872a828236e52ffac3761 645 Gene3D G3DSA:3.40.50.1110 106 246 4.8E-10 T 13-10-2018 IPR036514 SGNH hydrolase superfamily Astex_1707 0b94e82d97c872a828236e52ffac3761 645 Gene3D G3DSA:3.40.50.1110 403 544 2.7E-10 T 13-10-2018 IPR036514 SGNH hydrolase superfamily Astex_1707 0b94e82d97c872a828236e52ffac3761 645 Pfam PF03629 Carbohydrate esterase, sialic acid-specific acetylesterase 428 534 8.5E-8 T 13-10-2018 IPR005181 Sialate O-acetylesterase domain Astex_1707 0b94e82d97c872a828236e52ffac3761 645 Pfam PF03629 Carbohydrate esterase, sialic acid-specific acetylesterase 105 209 3.6E-9 T 13-10-2018 IPR005181 Sialate O-acetylesterase domain Astex_1707 0b94e82d97c872a828236e52ffac3761 645 SUPERFAMILY SSF49785 255 369 2.41E-12 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily Astex_3375 eaced7689a863264b79a77d41315116c 542 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 380 407 1.9E-17 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_3375 eaced7689a863264b79a77d41315116c 542 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 43 58 1.9E-17 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_3375 eaced7689a863264b79a77d41315116c 542 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 409 438 1.9E-17 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_3375 eaced7689a863264b79a77d41315116c 542 SUPERFAMILY SSF58104 264 535 1.05E-42 T 13-10-2018 Astex_3375 eaced7689a863264b79a77d41315116c 542 SMART SM00283 282 536 6.9E-25 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_3375 eaced7689a863264b79a77d41315116c 542 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 342 509 6.0E-28 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_3375 eaced7689a863264b79a77d41315116c 542 Gene3D G3DSA:1.10.287.950 250 541 8.8E-45 T 13-10-2018 Astex_0492 7e3e4c251e9056b77ba94a0da4a840ea 367 Gene3D G3DSA:2.102.10.10 21 160 4.5E-35 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 Astex_0492 7e3e4c251e9056b77ba94a0da4a840ea 367 SUPERFAMILY SSF50022 20 141 9.95E-34 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 Astex_0492 7e3e4c251e9056b77ba94a0da4a840ea 367 SUPERFAMILY SSF55961 133 364 1.07E-19 T 13-10-2018 Astex_0492 7e3e4c251e9056b77ba94a0da4a840ea 367 Pfam PF00355 Rieske [2Fe-2S] domain 25 110 6.2E-19 T 13-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Astex_2156 e91f0d87fea6da4599f1e10aa04a792c 537 Pfam PF13347 MFS/sugar transport protein 18 490 7.5E-48 T 13-10-2018 Astex_2156 e91f0d87fea6da4599f1e10aa04a792c 537 Gene3D G3DSA:1.20.1250.20 14 483 7.0E-17 T 13-10-2018 Astex_2156 e91f0d87fea6da4599f1e10aa04a792c 537 SUPERFAMILY SSF103473 9 488 2.22E-27 T 13-10-2018 IPR036259 MFS transporter superfamily Astex_1290 4331849df9ddb295b76ffc01254280cf 745 SUPERFAMILY SSF56935 31 745 7.94E-109 T 13-10-2018 Astex_1290 4331849df9ddb295b76ffc01254280cf 745 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 67 745 4.9E-77 T 13-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 Astex_1290 4331849df9ddb295b76ffc01254280cf 745 Gene3D G3DSA:2.170.130.10 47 175 1.1E-38 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_1290 4331849df9ddb295b76ffc01254280cf 745 Pfam PF00593 TonB dependent receptor 269 744 1.1E-45 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_1290 4331849df9ddb295b76ffc01254280cf 745 Gene3D G3DSA:2.40.170.20 182 745 4.6E-102 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_1290 4331849df9ddb295b76ffc01254280cf 745 Pfam PF07715 TonB-dependent Receptor Plug Domain 66 164 2.8E-20 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_0328 c6b1af3e3f579b8b1e62e36e76fc035f 562 Pfam PF03354 Phage Terminase 62 535 4.6E-18 T 13-10-2018 IPR005021 Terminase large subunit, Lambdalikevirus-type Astex_0328 c6b1af3e3f579b8b1e62e36e76fc035f 562 Gene3D G3DSA:3.40.50.300 57 240 1.2E-12 T 13-10-2018 Astex_3139 5d642161c443d342f3e85d6244902e41 209 Gene3D G3DSA:3.40.50.150 1 197 6.4E-21 T 13-10-2018 Astex_3139 5d642161c443d342f3e85d6244902e41 209 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 8 177 7.9E-7 T 13-10-2018 Astex_3139 5d642161c443d342f3e85d6244902e41 209 SUPERFAMILY SSF53335 1 168 2.72E-17 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Astex_2016 cd99a8c557fe841767495b67423f29a3 354 Gene3D G3DSA:1.25.40.10 140 277 1.0E-17 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_2016 cd99a8c557fe841767495b67423f29a3 354 SUPERFAMILY SSF48452 151 320 3.16E-16 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_1679 5ba91efe620078d7c8455811fd336903 184 Gene3D G3DSA:3.30.1330.60 63 178 2.0E-35 T 13-10-2018 IPR036737 OmpA-like domain superfamily Astex_1679 5ba91efe620078d7c8455811fd336903 184 SUPERFAMILY SSF103088 57 174 1.24E-32 T 13-10-2018 IPR036737 OmpA-like domain superfamily Astex_1679 5ba91efe620078d7c8455811fd336903 184 Pfam PF00691 OmpA family 78 173 6.0E-22 T 13-10-2018 IPR006665 OmpA-like domain Astex_1679 5ba91efe620078d7c8455811fd336903 184 Hamap MF_02204 Peptidoglycan-associated lipoprotein [pal]. 3 179 30.155 T 13-10-2018 IPR039001 Peptidoglycan-associated lipoprotein GO:0009279|GO:0051301 Astex_1679 5ba91efe620078d7c8455811fd336903 184 ProSitePatterns PS01068 OmpA-like domain. 111 155 - T 13-10-2018 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 Astex_1679 5ba91efe620078d7c8455811fd336903 184 TIGRFAM TIGR02802 Pal_lipo: peptidoglycan-associated lipoprotein 76 178 6.2E-42 T 13-10-2018 IPR014169 Peptidoglycan-associated lipoprotein, C-terminal GO:0009279 Astex_1679 5ba91efe620078d7c8455811fd336903 184 PRINTS PR01021 OMPA domain signature 79 101 6.6E-15 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 Astex_1679 5ba91efe620078d7c8455811fd336903 184 PRINTS PR01021 OMPA domain signature 109 124 6.6E-15 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 Astex_1679 5ba91efe620078d7c8455811fd336903 184 PRINTS PR01021 OMPA domain signature 124 140 6.6E-15 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 Astex_1706 7e928b1185ab554762fa6a4f9ae85ee6 66 Pfam PF04325 Protein of unknown function (DUF465) 8 53 5.9E-11 T 13-10-2018 IPR007420 Protein of unknown function DUF465 Astex_1706 7e928b1185ab554762fa6a4f9ae85ee6 66 Gene3D G3DSA:1.20.58.660 4 64 4.6E-6 T 13-10-2018 Astex_1740 64c63be38e33f4a71f6084b9e221b0de 648 Pfam PF00326 Prolyl oligopeptidase family 436 645 2.0E-44 T 13-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 Astex_1740 64c63be38e33f4a71f6084b9e221b0de 648 SUPERFAMILY SSF53474 391 645 2.37E-67 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1740 64c63be38e33f4a71f6084b9e221b0de 648 SUPERFAMILY SSF82171 45 371 6.02E-13 T 13-10-2018 Astex_1740 64c63be38e33f4a71f6084b9e221b0de 648 Gene3D G3DSA:3.40.50.1820 383 647 2.1E-74 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_0546 0e3ec4be1e0c2a8a5ab28dd1dd3ee790 530 Pfam PF05977 Transmembrane secretion effector 12 528 3.3E-200 T 13-10-2018 IPR010290 Transmembrane secretion effector Astex_0546 0e3ec4be1e0c2a8a5ab28dd1dd3ee790 530 Gene3D G3DSA:1.20.1250.20 16 402 4.3E-35 T 13-10-2018 Astex_0546 0e3ec4be1e0c2a8a5ab28dd1dd3ee790 530 SUPERFAMILY SSF103473 20 404 1.83E-40 T 13-10-2018 IPR036259 MFS transporter superfamily Astex_2496 8766d3060bfe4d88d7506e260ff16fbd 606 Pfam PF05960 Bacterial protein of unknown function (DUF885) 50 597 1.2E-163 T 13-10-2018 IPR010281 Protein of unknown function DUF885 Astex_2551 7fed71accdf58c4849126a968bd158d0 312 SUPERFAMILY SSF51735 101 277 1.01E-44 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_2551 7fed71accdf58c4849126a968bd158d0 312 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 108 277 2.5E-43 T 13-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 Astex_2551 7fed71accdf58c4849126a968bd158d0 312 Gene3D G3DSA:3.40.50.720 23 312 4.8E-101 T 13-10-2018 Astex_2551 7fed71accdf58c4849126a968bd158d0 312 Gene3D G3DSA:3.40.50.720 98 278 4.8E-101 T 13-10-2018 Astex_2551 7fed71accdf58c4849126a968bd158d0 312 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 143 156 - T 13-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 Astex_3786 f4baab92414f52ec1b9780a29d4432db 442 Pfam PF03743 Bacterial conjugation TrbI-like protein 225 436 7.8E-29 T 13-10-2018 IPR005498 Type IV secretion system, VirB10 / TraB / TrbI Astex_1100 0c491456a21d463266420445a38c61b9 537 Gene3D G3DSA:2.60.120.200 358 536 2.2E-17 T 13-10-2018 Astex_1100 0c491456a21d463266420445a38c61b9 537 Gene3D G3DSA:2.115.10.20 51 341 9.3E-72 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Astex_1100 0c491456a21d463266420445a38c61b9 537 Pfam PF04616 Glycosyl hydrolases family 43 54 328 1.5E-83 T 13-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 Astex_1100 0c491456a21d463266420445a38c61b9 537 SUPERFAMILY SSF49899 357 535 8.71E-23 T 13-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily Astex_1100 0c491456a21d463266420445a38c61b9 537 SUPERFAMILY SSF75005 53 336 3.38E-73 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Astex_1080 a4f4ad44a3416966038d1a5477ba954d 200 Pfam PF02230 Phospholipase/Carboxylesterase 3 184 1.0E-32 T 13-10-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 Astex_1080 a4f4ad44a3416966038d1a5477ba954d 200 Gene3D G3DSA:3.40.50.1820 2 196 1.4E-46 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1080 a4f4ad44a3416966038d1a5477ba954d 200 SUPERFAMILY SSF53474 3 195 2.89E-36 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1725 04ceb69b9ab76d74d522fe2cd29dcbad 216 SUPERFAMILY SSF56784 12 213 3.16E-27 T 13-10-2018 IPR036412 HAD-like superfamily Astex_1725 04ceb69b9ab76d74d522fe2cd29dcbad 216 Gene3D G3DSA:1.10.150.450 24 91 4.1E-33 T 13-10-2018 Astex_1725 04ceb69b9ab76d74d522fe2cd29dcbad 216 Gene3D G3DSA:3.40.50.1000 15 196 4.1E-33 T 13-10-2018 IPR023214 HAD superfamily Astex_1725 04ceb69b9ab76d74d522fe2cd29dcbad 216 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 14 191 6.9E-12 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 Astex_1725 04ceb69b9ab76d74d522fe2cd29dcbad 216 TIGRFAM TIGR01993 Pyr-5-nucltdase: pyrimidine 5'-nucleotidase 13 191 9.8E-54 T 13-10-2018 IPR010237 Pyrimidine 5-nucleotidase Astex_1725 04ceb69b9ab76d74d522fe2cd29dcbad 216 Pfam PF13419 Haloacid dehalogenase-like hydrolase 15 191 1.2E-7 T 13-10-2018 Astex_2922 d78f1067be421aba5e5bfff7e0794c94 104 Pfam PF04977 Septum formation initiator 17 95 3.8E-11 T 13-10-2018 IPR007060 Septum formation initiator FtsL/DivIC Astex_0796 c11e728fcd3b2412e76a98b4244f459b 141 Pfam PF04134 Protein of unknown function, DUF393 23 130 7.9E-9 T 13-10-2018 IPR007263 Protein of unknown function DUF393 Astex_1601 58b07bc36e7c76f5ccf3d0c333e352b9 215 SUPERFAMILY SSF56925 30 215 2.88E-28 T 13-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel Astex_1601 58b07bc36e7c76f5ccf3d0c333e352b9 215 Gene3D G3DSA:2.40.160.20 28 215 4.2E-49 T 13-10-2018 Astex_1601 58b07bc36e7c76f5ccf3d0c333e352b9 215 Pfam PF03922 OmpW family 30 215 2.3E-57 T 13-10-2018 IPR005618 Outer membrane protein, OmpW GO:0019867 Astex_3698 87671338dd3d2be7c7e4f6368a257fe2 98 Pfam PF10048 Predicted integral membrane protein (DUF2282) 39 93 3.2E-24 T 13-10-2018 IPR018740 Protein of unknown function DUF2282, integral membrane Astex_2489 61fbeb3269f8421b4ac5b67185ef64a6 396 Gene3D G3DSA:1.10.1200.160 333 365 5.0E-48 T 13-10-2018 Astex_2489 61fbeb3269f8421b4ac5b67185ef64a6 396 Gene3D G3DSA:2.40.128.260 211 384 5.0E-48 T 13-10-2018 Astex_2489 61fbeb3269f8421b4ac5b67185ef64a6 396 Pfam PF03743 Bacterial conjugation TrbI-like protein 209 385 2.6E-52 T 13-10-2018 IPR005498 Type IV secretion system, VirB10 / TraB / TrbI Astex_0422 9e17a1824296574be71c662f6369de46 228 Pfam PF09476 Pilus biogenesis CpaD protein (pilus_cpaD) 15 207 2.6E-46 T 13-10-2018 IPR019027 Pilus biogenesis CpaD-related Astex_0329 d7da027c6297a6c3de8570da24885199 412 Pfam PF04860 Phage portal protein 63 385 2.3E-71 T 13-10-2018 IPR006944 Bacteriophage/Gene transfer agent portal protein Astex_0329 d7da027c6297a6c3de8570da24885199 412 TIGRFAM TIGR01537 portal_HK97: phage portal protein, HK97 family 56 386 1.7E-54 T 13-10-2018 IPR006427 Phage portal protein, HK97 Astex_1678 9280b5684146d9bf53b8a2550cad17ae 311 Pfam PF03783 Curli production assembly/transport component CsgG 78 238 4.6E-8 T 13-10-2018 IPR005534 Curli production assembly/transport component CsgG GO:0030288 Astex_0333 46c90f7c1c0e0547689e4e181e1e0854 101 Pfam PF05135 Phage gp6-like head-tail connector protein 14 97 7.0E-11 T 13-10-2018 IPR021146 Phage gp6-like head-tail connector protein Astex_0333 46c90f7c1c0e0547689e4e181e1e0854 101 Gene3D G3DSA:1.10.3230.30 6 100 1.1E-15 T 13-10-2018 Astex_2315 c77cc0ede6df49edcfce35b616e9abef 78 Gene3D G3DSA:2.20.25.10 28 78 1.8E-18 T 13-10-2018 Astex_2315 c77cc0ede6df49edcfce35b616e9abef 78 Hamap MF_01187 UPF0434 protein YcaR [ycaR]. 21 74 24.775 T 13-10-2018 IPR038053 Uncharacterised protein family UPF0434 Astex_2315 c77cc0ede6df49edcfce35b616e9abef 78 Pfam PF03966 Trm112p-like protein 22 61 1.4E-6 T 13-10-2018 IPR005651 Trm112-like Astex_2315 c77cc0ede6df49edcfce35b616e9abef 78 SUPERFAMILY SSF158997 21 74 9.94E-18 T 13-10-2018 Astex_3704 e7c24729aea52410722ee94e96a70d48 214 Pfam PF06532 Protein of unknown function (DUF1109) 12 208 6.6E-19 T 13-10-2018 IPR009495 Anti-sigma-F factor NrsF Astex_1648 055c3b3e835f6efe97c92f10f4fa4fa5 156 ProSitePatterns PS00018 EF-hand calcium-binding domain. 88 100 - T 13-10-2018 IPR018247 EF-Hand 1, calcium-binding site Astex_1648 055c3b3e835f6efe97c92f10f4fa4fa5 156 Gene3D G3DSA:1.10.238.10 35 103 2.0E-9 T 13-10-2018 Astex_1648 055c3b3e835f6efe97c92f10f4fa4fa5 156 ProSitePatterns PS00018 EF-hand calcium-binding domain. 44 56 - T 13-10-2018 IPR018247 EF-Hand 1, calcium-binding site Astex_1648 055c3b3e835f6efe97c92f10f4fa4fa5 156 Pfam PF13202 EF hand 39 59 4.5E-6 T 13-10-2018 IPR002048 EF-hand domain GO:0005509 Astex_1648 055c3b3e835f6efe97c92f10f4fa4fa5 156 Pfam PF13202 EF hand 86 99 0.14 T 13-10-2018 IPR002048 EF-hand domain GO:0005509 Astex_1648 055c3b3e835f6efe97c92f10f4fa4fa5 156 Pfam PF13202 EF hand 104 123 0.0075 T 13-10-2018 IPR002048 EF-hand domain GO:0005509 Astex_1648 055c3b3e835f6efe97c92f10f4fa4fa5 156 SUPERFAMILY SSF47473 39 125 1.56E-11 T 13-10-2018 IPR011992 EF-hand domain pair Astex_0300 6660abe298ab4bca14dfb385d2b48dc1 356 Gene3D G3DSA:1.10.150.130 68 180 5.2E-13 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal Astex_0300 6660abe298ab4bca14dfb385d2b48dc1 356 Gene3D G3DSA:1.10.443.10 183 342 4.7E-25 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 Astex_0300 6660abe298ab4bca14dfb385d2b48dc1 356 Pfam PF00589 Phage integrase family 191 338 3.6E-16 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 Astex_0300 6660abe298ab4bca14dfb385d2b48dc1 356 SUPERFAMILY SSF56349 70 341 1.97E-49 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 Astex_1242 767e5e378aa5e327f8c816e67fc97081 228 Pfam PF07087 Protein of unknown function (DUF1353) 56 146 2.9E-31 T 13-10-2018 IPR010767 Campylobacter phage CGC-2007, Cje0229 Astex_3519 1d3c5b7a6e9bc3e3745674055672c209 74 Pfam PF13773 Domain of unknown function (DUF4170) 4 71 7.3E-35 T 13-10-2018 IPR025226 Protein of unknown function DUF4170 Astex_3519 1d3c5b7a6e9bc3e3745674055672c209 74 Gene3D G3DSA:3.30.70.2400 1 74 2.1E-32 T 13-10-2018 Astex_0885 399141d715a187e4375a515580990cf1 200 Gene3D G3DSA:1.10.8.420 5 54 1.9E-9 T 13-10-2018 Astex_0885 399141d715a187e4375a515580990cf1 200 TIGRFAM TIGR00615 recR: recombination protein RecR 7 200 1.0E-59 T 13-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 Astex_0885 399141d715a187e4375a515580990cf1 200 Pfam PF02132 RecR protein 44 80 3.4E-12 T 13-10-2018 IPR023628 Recombination protein RecR, C4-type zinc finger Astex_0885 399141d715a187e4375a515580990cf1 200 SUPERFAMILY SSF111304 7 200 7.19E-63 T 13-10-2018 IPR023627 Recombination protein RecR Astex_0885 399141d715a187e4375a515580990cf1 200 Hamap MF_00017 Recombination protein RecR [recR]. 1 200 87.23 T 13-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 Astex_0885 399141d715a187e4375a515580990cf1 200 Gene3D G3DSA:3.40.1360.10 79 200 2.9E-38 T 13-10-2018 Astex_0885 399141d715a187e4375a515580990cf1 200 Pfam PF13662 Toprim domain 84 173 1.4E-17 T 13-10-2018 IPR006171 TOPRIM domain Astex_0588 c45c263292de6d7c0b567522274920b9 415 Gene3D G3DSA:3.30.750.140 245 361 2.6E-9 T 13-10-2018 IPR038610 FliK-like, C-terminal domain superfamily Astex_0588 c45c263292de6d7c0b567522274920b9 415 Pfam PF02120 Flagellar hook-length control protein FliK 268 348 9.5E-14 T 13-10-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal Astex_0620 099c5303d745178d53ef89be6d98de10 168 Pfam PF07310 PAS domain 16 149 2.5E-18 T 13-10-2018 IPR009922 Protein of unknown function DUF1457 Astex_0708 b94d3d71ae0f8792fa87ed85b1a88ba6 196 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 6 181 6.3E-54 T 13-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 Astex_0708 b94d3d71ae0f8792fa87ed85b1a88ba6 196 Pfam PF00694 Aconitase C-terminal domain 18 124 8.6E-26 T 13-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 Astex_0708 b94d3d71ae0f8792fa87ed85b1a88ba6 196 Gene3D G3DSA:3.20.19.10 1 173 1.9E-61 T 13-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 Astex_0708 b94d3d71ae0f8792fa87ed85b1a88ba6 196 SUPERFAMILY SSF52016 5 191 6.67E-48 T 13-10-2018 Astex_2833 535abbb7165b78df4f9987ca02f3d8ae 478 SUPERFAMILY SSF63829 326 455 4.8E-9 T 13-10-2018 Astex_2833 535abbb7165b78df4f9987ca02f3d8ae 478 Pfam PF05787 Bacterial protein of unknown function (DUF839) 49 459 1.0E-64 T 13-10-2018 IPR008557 Protein of unknown function DUF839 Astex_3162 0263f0cd83fcd2ecf186aa150681ed9e 237 Gene3D G3DSA:3.30.1950.10 52 116 3.4E-8 T 13-10-2018 Astex_3162 0263f0cd83fcd2ecf186aa150681ed9e 237 Pfam PF02563 Polysaccharide biosynthesis/export protein 44 115 1.9E-15 T 13-10-2018 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 Astex_3162 0263f0cd83fcd2ecf186aa150681ed9e 237 Gene3D G3DSA:3.10.560.10 117 206 7.1E-12 T 13-10-2018 Astex_0901 64cf54732bd6691c88560cf4dce2dfa7 342 Gene3D G3DSA:3.90.1720.10 19 124 5.1E-15 T 13-10-2018 Astex_0901 64cf54732bd6691c88560cf4dce2dfa7 342 SUPERFAMILY SSF54001 30 155 4.9E-22 T 13-10-2018 IPR038765 Papain-like cysteine peptidase superfamily Astex_0901 64cf54732bd6691c88560cf4dce2dfa7 342 Pfam PF05257 CHAP domain 29 102 4.2E-11 T 13-10-2018 IPR007921 CHAP domain Astex_1525 874a66e198a358e5280c23eecca20023 82 Pfam PF11625 Protein of unknown function (DUF3253) 3 78 5.0E-21 T 13-10-2018 IPR021660 Protein of unknown function DUF3253 Astex_1525 874a66e198a358e5280c23eecca20023 82 SUPERFAMILY SSF46785 2 79 7.82E-22 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_1525 874a66e198a358e5280c23eecca20023 82 Gene3D G3DSA:1.10.10.10 2 80 9.2E-22 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1017 c677d8745f4f462bfcbcbb77b94a2678 253 Gene3D G3DSA:3.40.1280.10 102 253 9.9E-37 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Astex_1017 c677d8745f4f462bfcbcbb77b94a2678 253 SUPERFAMILY SSF75217 106 252 6.54E-32 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases Astex_1017 c677d8745f4f462bfcbcbb77b94a2678 253 SUPERFAMILY SSF55315 4 96 4.0E-11 T 13-10-2018 IPR029064 50S ribosomal protein L30e-like Astex_1017 c677d8745f4f462bfcbcbb77b94a2678 253 Pfam PF00588 SpoU rRNA Methylase family 114 249 4.0E-24 T 13-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 Astex_1447 c92ac407844459978ddf9d6c24dc1113 70 Pfam PF01381 Helix-turn-helix 5 54 1.4E-14 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Astex_1447 c92ac407844459978ddf9d6c24dc1113 70 Gene3D G3DSA:1.10.260.40 1 63 1.5E-23 T 13-10-2018 Astex_1447 c92ac407844459978ddf9d6c24dc1113 70 SMART SM00530 4 59 6.2E-15 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Astex_1447 c92ac407844459978ddf9d6c24dc1113 70 SUPERFAMILY SSF47413 2 62 4.29E-17 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Astex_0638 6dac0b5ef7073989d03685920616e9b3 581 ProSitePatterns PS01271 Sodium:sulfate symporter family signature. 530 546 - T 13-10-2018 IPR031312 Sodium/sulphate symporter, conserved site Reactome: R-HSA-433137 Astex_0638 6dac0b5ef7073989d03685920616e9b3 581 SUPERFAMILY SSF116726 299 368 8.37E-5 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 Astex_0638 6dac0b5ef7073989d03685920616e9b3 581 Pfam PF03600 Citrate transporter 21 529 1.4E-47 T 13-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 Astex_2371 92fb20961a64c8bce7d7f564a6a4b92b 90 SUPERFAMILY SSF55729 1 89 2.48E-22 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Astex_2371 92fb20961a64c8bce7d7f564a6a4b92b 90 Gene3D G3DSA:3.40.630.30 1 90 2.2E-20 T 13-10-2018 Astex_2371 92fb20961a64c8bce7d7f564a6a4b92b 90 Pfam PF14542 GCN5-related N-acetyl-transferase 12 88 9.1E-20 T 13-10-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase Astex_0848 d2657669a1cb55919eabe71c5e6bd5e1 435 Pfam PF04932 O-Antigen ligase 209 368 6.9E-19 T 13-10-2018 IPR007016 O-antigen ligase-related Astex_3192 757aa61d689637f920272a7262996dfc 215 SMART SM01207 14 196 8.8E-81 T 13-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 Astex_3192 757aa61d689637f920272a7262996dfc 215 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 8 205 4.0E-53 T 13-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 Astex_3192 757aa61d689637f920272a7262996dfc 215 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 11 204 20.008 T 13-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 Astex_3192 757aa61d689637f920272a7262996dfc 215 Pfam PF02660 Glycerol-3-phosphate acyltransferase 16 195 4.3E-50 T 13-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 Astex_2375 4654dcba9cc056d21aef741472c4c08d 291 Pfam PF00892 EamA-like transporter family 11 114 7.1E-8 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Astex_2375 4654dcba9cc056d21aef741472c4c08d 291 Pfam PF00892 EamA-like transporter family 147 277 7.7E-16 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 Astex_2375 4654dcba9cc056d21aef741472c4c08d 291 SUPERFAMILY SSF103481 188 281 1.05E-11 T 13-10-2018 Astex_2375 4654dcba9cc056d21aef741472c4c08d 291 SUPERFAMILY SSF103481 47 135 1.96E-7 T 13-10-2018 Astex_1885 44de7712ae34ad1f47a2aedab527bd33 311 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 2 309 6.3E-87 T 13-10-2018 IPR007296 Domain of unknown function DUF403 Astex_1076 65c81bf18c6a5533c1b8d1a9c8af2e12 302 Gene3D G3DSA:3.30.420.310 81 300 1.6E-64 T 13-10-2018 Astex_1076 65c81bf18c6a5533c1b8d1a9c8af2e12 302 Pfam PF05035 2-keto-3-deoxy-galactonokinase 10 295 6.4E-95 T 13-10-2018 IPR007729 2-keto-3-deoxy-galactonokinase GO:0008671|GO:0034194 KEGG: 00052+2.7.1.58|MetaCyc: PWY-7130 Astex_1076 65c81bf18c6a5533c1b8d1a9c8af2e12 302 Gene3D G3DSA:3.30.420.300 1 80 8.5E-23 T 13-10-2018 Astex_1076 65c81bf18c6a5533c1b8d1a9c8af2e12 302 SUPERFAMILY SSF53067 6 271 2.7E-5 T 13-10-2018 Astex_1895 90f25ab4a4cff51a66d169d5a6b90145 982 Pfam PF00593 TonB dependent receptor 435 946 3.7E-29 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_1895 90f25ab4a4cff51a66d169d5a6b90145 982 Pfam PF07715 TonB-dependent Receptor Plug Domain 60 170 6.7E-8 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_1895 90f25ab4a4cff51a66d169d5a6b90145 982 SUPERFAMILY SSF56935 29 963 3.36E-71 T 13-10-2018 Astex_1895 90f25ab4a4cff51a66d169d5a6b90145 982 Gene3D G3DSA:2.170.130.10 42 173 9.0E-12 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_1895 90f25ab4a4cff51a66d169d5a6b90145 982 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 42 982 5.7E-193 T 13-10-2018 IPR010104 Bacterial TonB-dependent receptor Astex_2691 52e05ee161a19270f972024fe11fa832 115 SUPERFAMILY SSF52833 3 114 3.28E-32 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Astex_2691 52e05ee161a19270f972024fe11fa832 115 Pfam PF03960 ArsC family 6 112 3.2E-16 T 13-10-2018 IPR006660 Arsenate reductase-like Astex_2691 52e05ee161a19270f972024fe11fa832 115 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 3 111 5.7E-26 T 13-10-2018 IPR006504 Transcriptional regulator Spx/MgsR Astex_2691 52e05ee161a19270f972024fe11fa832 115 Gene3D G3DSA:3.40.30.10 2 115 2.3E-41 T 13-10-2018 Astex_0532 5ead628e1012ec4c1637574768d98748 199 Gene3D G3DSA:1.10.3290.10 6 197 7.2E-54 T 13-10-2018 IPR036597 Fido-like domain superfamily Astex_0532 5ead628e1012ec4c1637574768d98748 199 Pfam PF02661 Fic/DOC family 56 153 7.7E-19 T 13-10-2018 IPR003812 Fido domain Astex_0532 5ead628e1012ec4c1637574768d98748 199 SUPERFAMILY SSF140931 53 194 5.49E-35 T 13-10-2018 IPR036597 Fido-like domain superfamily Astex_0650 58efcc9bf6aa6a0b221b09f96de8d76c 116 SUPERFAMILY SSF52821 9 116 4.19E-25 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily Astex_0650 58efcc9bf6aa6a0b221b09f96de8d76c 116 Pfam PF00581 Rhodanese-like domain 15 110 1.7E-13 T 13-10-2018 IPR001763 Rhodanese-like domain Astex_0650 58efcc9bf6aa6a0b221b09f96de8d76c 116 SMART SM00450 14 113 3.8E-16 T 13-10-2018 IPR001763 Rhodanese-like domain Astex_0650 58efcc9bf6aa6a0b221b09f96de8d76c 116 Gene3D G3DSA:3.40.250.10 6 116 2.9E-23 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily Astex_0022 34f0f98238447a67db6a5d5a1abde991 185 Gene3D G3DSA:2.60.40.1890 61 175 9.5E-38 T 13-10-2018 IPR036182 Copper chaperone PCuAC superfamily Astex_0022 34f0f98238447a67db6a5d5a1abde991 185 SUPERFAMILY SSF110087 54 173 6.54E-38 T 13-10-2018 IPR036182 Copper chaperone PCuAC superfamily Astex_0022 34f0f98238447a67db6a5d5a1abde991 185 Pfam PF04314 Copper chaperone PCu(A)C 60 167 8.1E-36 T 13-10-2018 IPR007410 Copper chaperone PCuAC Astex_3276 510342d7f4ce380d50939efd0f03a8ae 355 Pfam PF01944 Stage II sporulation protein M 124 301 1.4E-25 T 13-10-2018 IPR002798 Stage II sporulation protein M-like Astex_3159 f4624949b809baa367315b10e75e9cb0 433 Pfam PF04932 O-Antigen ligase 210 350 6.7E-11 T 13-10-2018 IPR007016 O-antigen ligase-related Astex_0661 d84978b79eeef32fde01d9655863f045 291 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 38 271 7.3E-38 T 13-10-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system Astex_3798 61d082868057e12577743d4c3694d7dc 461 Pfam PF06122 Conjugative relaxosome accessory transposon protein 29 378 3.9E-109 T 13-10-2018 IPR010927 Type IV conjugative transfer system protein TraH Astex_2539 cf30572d74ca426a137e5077bb180c19 136 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 131 1.2E-14 T 13-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain Astex_2539 cf30572d74ca426a137e5077bb180c19 136 Gene3D G3DSA:3.10.180.10 2 134 1.4E-30 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Astex_2539 cf30572d74ca426a137e5077bb180c19 136 SUPERFAMILY SSF54593 8 135 6.58E-24 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Astex_1682 0bb96eeb8011b5a034337c3181e8778c 160 Pfam PF02472 Biopolymer transport protein ExbD/TolR 23 144 9.3E-29 T 13-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 Astex_1682 0bb96eeb8011b5a034337c3181e8778c 160 Gene3D G3DSA:3.30.420.270 72 141 3.2E-17 T 13-10-2018 Astex_3367 9aec8fc5534c5af1018f64e57463f9d8 244 SUPERFAMILY SSF56935 39 243 8.85E-12 T 13-10-2018 Astex_1099 7675ac95dd4b495f88c3a9872216ac7e 1121 Gene3D G3DSA:2.170.130.10 37 184 5.0E-15 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_1099 7675ac95dd4b495f88c3a9872216ac7e 1121 SUPERFAMILY SSF56935 49 1121 3.66E-71 T 13-10-2018 Astex_1099 7675ac95dd4b495f88c3a9872216ac7e 1121 Pfam PF07715 TonB-dependent Receptor Plug Domain 66 178 7.5E-14 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_1099 7675ac95dd4b495f88c3a9872216ac7e 1121 Pfam PF00593 TonB dependent receptor 609 1120 1.8E-23 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_1568 ca179fd3ef5a573cf439a0c5dbd8fb85 147 SUPERFAMILY SSF53098 1 140 3.67E-58 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily Astex_1568 ca179fd3ef5a573cf439a0c5dbd8fb85 147 Gene3D G3DSA:3.30.420.10 1 146 4.4E-60 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 Astex_1568 ca179fd3ef5a573cf439a0c5dbd8fb85 147 Hamap MF_00042 Ribonuclease H [rnhA]. 1 147 33.965 T 13-10-2018 IPR022892 Ribonuclease HI GO:0004523 Astex_1568 ca179fd3ef5a573cf439a0c5dbd8fb85 147 Pfam PF00075 RNase H 2 140 6.2E-50 T 13-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 Astex_1040 cb97e056340f55c735c02df3ca6d82a4 425 Gene3D G3DSA:3.90.1150.10 289 425 3.8E-50 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 Astex_1040 cb97e056340f55c735c02df3ca6d82a4 425 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 196 210 - T 13-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 Astex_1040 cb97e056340f55c735c02df3ca6d82a4 425 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 4 420 3.2E-140 T 13-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 Astex_1040 cb97e056340f55c735c02df3ca6d82a4 425 PIRSF PIRSF001434 1 424 5.6E-132 T 13-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 Astex_1040 cb97e056340f55c735c02df3ca6d82a4 425 SUPERFAMILY SSF53383 1 420 6.05E-131 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase Astex_1040 cb97e056340f55c735c02df3ca6d82a4 425 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 3 420 3.1E-197 T 13-10-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 Astex_1040 cb97e056340f55c735c02df3ca6d82a4 425 Gene3D G3DSA:3.40.640.10 1 285 3.8E-103 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 Astex_3083 da3840d4ee3732cdf39a480730502bcd 584 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 422 449 2.6E-19 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_3083 da3840d4ee3732cdf39a480730502bcd 584 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 451 480 2.6E-19 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_3083 da3840d4ee3732cdf39a480730502bcd 584 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 28 53 2.6E-19 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_3083 da3840d4ee3732cdf39a480730502bcd 584 Gene3D G3DSA:1.20.1480.50 192 289 7.6E-15 T 13-10-2018 Astex_3083 da3840d4ee3732cdf39a480730502bcd 584 SMART SM00283 331 578 2.6E-33 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_3083 da3840d4ee3732cdf39a480730502bcd 584 SUPERFAMILY SSF58104 263 575 1.83E-56 T 13-10-2018 Astex_3083 da3840d4ee3732cdf39a480730502bcd 584 SMART SM00304 234 287 2.8E-6 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 Astex_3083 da3840d4ee3732cdf39a480730502bcd 584 Gene3D G3DSA:1.10.287.950 290 578 1.8E-51 T 13-10-2018 Astex_3083 da3840d4ee3732cdf39a480730502bcd 584 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 397 544 5.9E-28 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_2110 76bbe0ffd049fee1536ba09cb535723a 244 SUPERFAMILY SSF51110 155 241 1.58E-13 T 13-10-2018 IPR036426 Bulb-type lectin domain superfamily Astex_2110 76bbe0ffd049fee1536ba09cb535723a 244 Gene3D G3DSA:2.90.10.10 143 192 8.0E-9 T 13-10-2018 IPR036426 Bulb-type lectin domain superfamily Astex_2110 76bbe0ffd049fee1536ba09cb535723a 244 Gene3D G3DSA:2.90.10.10 193 244 3.0E-7 T 13-10-2018 IPR036426 Bulb-type lectin domain superfamily Astex_2875 5847dc2be2d37626c3eefc82bff617bb 258 Pfam PF01026 TatD related DNase 3 253 1.8E-71 T 13-10-2018 IPR001130 TatD family GO:0016788 Astex_2875 5847dc2be2d37626c3eefc82bff617bb 258 SUPERFAMILY SSF51556 2 253 1.15E-78 T 13-10-2018 IPR032466 Metal-dependent hydrolase Astex_2875 5847dc2be2d37626c3eefc82bff617bb 258 Gene3D G3DSA:3.20.20.140 1 256 4.1E-82 T 13-10-2018 Astex_2875 5847dc2be2d37626c3eefc82bff617bb 258 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 2 253 1.9E-74 T 13-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 Astex_2875 5847dc2be2d37626c3eefc82bff617bb 258 PIRSF PIRSF005902 1 255 1.2E-65 T 13-10-2018 IPR001130 TatD family GO:0016788 Astex_1536 4faa108c25490951efc8048cb9d4c1b7 258 Gene3D G3DSA:3.30.2010.10 62 148 6.2E-6 T 13-10-2018 Astex_1536 4faa108c25490951efc8048cb9d4c1b7 258 Pfam PF01435 Peptidase family M48 71 250 7.6E-40 T 13-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 Astex_1560 29fbcd75b732fb81eaa34f6cf24454b1 169 Pfam PF09656 Putative transmembrane protein (PGPGW) 54 102 1.7E-5 T 13-10-2018 IPR019099 Uncharacterised protein family PGPGW, transmembrane Astex_2115 76381da496d34b264a13f5097a44a7b7 339 Gene3D G3DSA:3.40.1190.20 2 339 1.4E-106 T 13-10-2018 IPR029056 Ribokinase-like Astex_2115 76381da496d34b264a13f5097a44a7b7 339 Pfam PF00294 pfkB family carbohydrate kinase 6 309 6.6E-30 T 13-10-2018 IPR011611 Carbohydrate kinase PfkB Astex_2115 76381da496d34b264a13f5097a44a7b7 339 SUPERFAMILY SSF53613 3 330 1.23E-66 T 13-10-2018 IPR029056 Ribokinase-like Astex_3293 a11a155bcbd92e5eebb62bfdb3c43a30 425 Gene3D G3DSA:1.20.1250.20 7 420 7.8E-77 T 13-10-2018 Astex_3293 a11a155bcbd92e5eebb62bfdb3c43a30 425 SUPERFAMILY SSF103473 11 421 3.66E-75 T 13-10-2018 IPR036259 MFS transporter superfamily Astex_3293 a11a155bcbd92e5eebb62bfdb3c43a30 425 Pfam PF07690 Major Facilitator Superfamily 24 379 1.6E-52 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Astex_3582 7def634458c302674884263744f1d146 320 SUPERFAMILY SSF53822 34 312 2.67E-72 T 13-10-2018 IPR028082 Periplasmic binding protein-like I Astex_3582 7def634458c302674884263744f1d146 320 Gene3D G3DSA:3.40.50.2300 42 293 1.6E-82 T 13-10-2018 Astex_3582 7def634458c302674884263744f1d146 320 Pfam PF13407 Periplasmic binding protein domain 34 292 7.9E-54 T 13-10-2018 IPR025997 Periplasmic binding protein Astex_3582 7def634458c302674884263744f1d146 320 Gene3D G3DSA:3.40.50.2300 133 274 1.6E-82 T 13-10-2018 Astex_1495 b0224b48699724924c1b55f2b5aac712 544 SUPERFAMILY SSF55729 337 514 2.28E-14 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Astex_1495 b0224b48699724924c1b55f2b5aac712 544 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 231 516 7.1E-82 T 13-10-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal Astex_1880 05a1f68e4203a79559a4063cdcfb1993 292 Gene3D G3DSA:3.30.70.2970 55 170 1.5E-20 T 13-10-2018 Astex_1880 05a1f68e4203a79559a4063cdcfb1993 292 Gene3D G3DSA:3.30.110.170 47 223 1.5E-20 T 13-10-2018 Astex_1880 05a1f68e4203a79559a4063cdcfb1993 292 Pfam PF04402 Protein of unknown function (DUF541) 43 266 1.9E-21 T 13-10-2018 IPR007497 Protein of unknown function DUF541 Astex_2104 eb9da887dae05ddc774a880cc78bea39 169 PIRSF PIRSF030820 6 167 3.9E-41 T 13-10-2018 IPR008318 Uncharacterised conserved protein UCP030820 Astex_2104 eb9da887dae05ddc774a880cc78bea39 169 Pfam PF06073 Bacterial protein of unknown function (DUF934) 57 163 3.1E-35 T 13-10-2018 IPR008318 Uncharacterised conserved protein UCP030820 Astex_2290 c49f15e7499d518eea2ec7cac4b45aab 386 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 38 377 4.1E-77 T 13-10-2018 Astex_2290 c49f15e7499d518eea2ec7cac4b45aab 386 SUPERFAMILY SSF48208 12 383 1.1E-79 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 Astex_2290 c49f15e7499d518eea2ec7cac4b45aab 386 Gene3D G3DSA:1.50.10.10 2 385 2.9E-66 T 13-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 Astex_2304 44e3b2e8cfa7e8aa63a2f579b64b0146 335 Gene3D G3DSA:3.90.550.10 1 246 3.4E-40 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_2304 44e3b2e8cfa7e8aa63a2f579b64b0146 335 Pfam PF00535 Glycosyl transferase family 2 5 135 3.4E-28 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 Astex_2304 44e3b2e8cfa7e8aa63a2f579b64b0146 335 SUPERFAMILY SSF53448 4 219 1.97E-46 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_2402 ef901888988bf9825de69beed4c9e777 487 SUPERFAMILY SSF56935 89 487 2.56E-5 T 13-10-2018 Astex_2402 ef901888988bf9825de69beed4c9e777 487 Pfam PF13372 Alginate export 92 478 2.3E-61 T 13-10-2018 IPR025388 Alginate export domain Astex_3181 daf34e4c598e73ede5e43ff9f073a953 95 SUPERFAMILY SSF141000 3 93 1.27E-28 T 13-10-2018 IPR036113 Glu-tRNAGln amidotransferase superfamily, subunit C GO:0006450 Astex_3181 daf34e4c598e73ede5e43ff9f073a953 95 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 20 90 1.2E-20 T 13-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 Astex_3181 daf34e4c598e73ede5e43ff9f073a953 95 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 3 95 8.9E-28 T 13-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 Astex_3181 daf34e4c598e73ede5e43ff9f073a953 95 Gene3D G3DSA:1.10.20.60 1 93 9.3E-25 T 13-10-2018 Astex_3181 daf34e4c598e73ede5e43ff9f073a953 95 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 2 95 23.608 T 13-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 Astex_0789 3926d7f944220189fbec9d5fbecb96ad 193 Gene3D G3DSA:2.40.128.110 27 193 5.0E-51 T 13-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily Astex_0789 3926d7f944220189fbec9d5fbecb96ad 193 SUPERFAMILY SSF101874 25 192 4.84E-52 T 13-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily Astex_0789 3926d7f944220189fbec9d5fbecb96ad 193 Pfam PF04264 YceI-like domain 29 190 2.5E-41 T 13-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like Astex_0789 3926d7f944220189fbec9d5fbecb96ad 193 SMART SM00867 28 191 5.3E-62 T 13-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like Astex_3546 9a286e1735b877ef60937603030c2fc9 147 Pfam PF00072 Response regulator receiver domain 16 126 9.8E-24 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_3546 9a286e1735b877ef60937603030c2fc9 147 Gene3D G3DSA:3.40.50.12740 12 147 1.1E-33 T 13-10-2018 Astex_3546 9a286e1735b877ef60937603030c2fc9 147 SMART SM00448 14 129 3.7E-29 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_3546 9a286e1735b877ef60937603030c2fc9 147 SUPERFAMILY SSF52172 14 144 3.7E-32 T 13-10-2018 IPR011006 CheY-like superfamily Astex_3177 de82af47d2c4176c3feb78567c98a382 662 TIGRFAM TIGR00728 OPT_sfam: oligopeptide transporter, OPT superfamily 8 609 4.0E-94 T 13-10-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 Astex_3177 de82af47d2c4176c3feb78567c98a382 662 Pfam PF03169 OPT oligopeptide transporter protein 8 611 1.4E-94 T 13-10-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 Astex_3177 de82af47d2c4176c3feb78567c98a382 662 TIGRFAM TIGR00733 TIGR00733: oligopeptide transporter, OPT family 8 613 6.3E-191 T 13-10-2018 IPR004814 Oligopeptide transporter OPT Astex_0765 a20d930d8b18a0ef7f6375f04a4561ad 95 Pfam PF11342 Protein of unknown function (DUF3144) 11 86 2.0E-20 T 13-10-2018 IPR021490 Protein of unknown function DUF3144 Astex_0914 90a45123a9573145633099e8c2d90c83 358 SUPERFAMILY SSF75620 19 350 1.83E-123 T 13-10-2018 Astex_0914 90a45123a9573145633099e8c2d90c83 358 Pfam PF00472 RF-1 domain 210 318 4.0E-37 T 13-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 Astex_0914 90a45123a9573145633099e8c2d90c83 358 SMART SM00937 63 177 9.8E-55 T 13-10-2018 IPR005139 Peptide chain release factor GO:0006415 Astex_0914 90a45123a9573145633099e8c2d90c83 358 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 5 354 37.908 T 13-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 Astex_0914 90a45123a9573145633099e8c2d90c83 358 Gene3D G3DSA:3.30.160.20 209 294 7.7E-96 T 13-10-2018 Astex_0914 90a45123a9573145633099e8c2d90c83 358 Pfam PF03462 PCRF domain 16 202 1.2E-63 T 13-10-2018 IPR005139 Peptide chain release factor GO:0006415 Astex_0914 90a45123a9573145633099e8c2d90c83 358 Gene3D G3DSA:3.30.70.1660 111 339 7.7E-96 T 13-10-2018 Astex_0914 90a45123a9573145633099e8c2d90c83 358 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 226 242 - T 13-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 Astex_0914 90a45123a9573145633099e8c2d90c83 358 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 8 355 2.1E-144 T 13-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 Astex_0382 637d5dbdd542aeb89c018f254ea05539 378 SUPERFAMILY SSF56601 10 373 9.73E-67 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like Astex_0382 637d5dbdd542aeb89c018f254ea05539 378 Gene3D G3DSA:3.40.710.30 5 378 2.6E-107 T 13-10-2018 Astex_0382 637d5dbdd542aeb89c018f254ea05539 378 Pfam PF00144 Beta-lactamase 19 358 1.5E-63 T 13-10-2018 IPR001466 Beta-lactamase-related Astex_2992 7fb5600b17a7c61b5bd5a00b15aed29a 145 Gene3D G3DSA:3.30.460.40 2 142 6.3E-20 T 13-10-2018 Astex_2992 7fb5600b17a7c61b5bd5a00b15aed29a 145 SUPERFAMILY SSF81301 18 139 2.32E-10 T 13-10-2018 Astex_3327 ad0ae6750031ff21b30e90fda3d50deb 453 Gene3D G3DSA:1.20.1530.20 35 443 2.8E-89 T 13-10-2018 IPR038770 Sodium/solute symporter superfamily Astex_3327 ad0ae6750031ff21b30e90fda3d50deb 453 Pfam PF00999 Sodium/hydrogen exchanger family 44 428 1.3E-54 T 13-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 Astex_1043 c5872da055db4a609a7d9029e90baeac 707 Gene3D G3DSA:2.170.130.10 38 173 2.7E-30 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_1043 c5872da055db4a609a7d9029e90baeac 707 SUPERFAMILY SSF56935 22 705 1.34E-120 T 13-10-2018 Astex_1043 c5872da055db4a609a7d9029e90baeac 707 Pfam PF07715 TonB-dependent Receptor Plug Domain 57 162 5.0E-15 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_1043 c5872da055db4a609a7d9029e90baeac 707 Pfam PF00593 TonB dependent receptor 235 705 9.8E-51 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_1043 c5872da055db4a609a7d9029e90baeac 707 Gene3D G3DSA:2.40.170.20 174 707 9.2E-106 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_1043 c5872da055db4a609a7d9029e90baeac 707 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 57 705 2.4E-93 T 13-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 Astex_2227 851d5ac6ce88053b902eaa8e9e4ed20a 205 Gene3D G3DSA:1.10.10.10 7 69 1.6E-8 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_2227 851d5ac6ce88053b902eaa8e9e4ed20a 205 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 68 3.2E-6 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 Astex_2227 851d5ac6ce88053b902eaa8e9e4ed20a 205 SUPERFAMILY SSF46785 5 72 8.16E-7 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_1711 4b6d846cc1f6a420dfe97c7116d1b47c 74 Pfam PF06698 Protein of unknown function (DUF1192) 22 69 7.8E-17 T 13-10-2018 IPR009579 Protein of unknown function DUF1192 Astex_3055 1fa9f300a48fadc780d3bb1d114e9391 146 Gene3D G3DSA:1.10.287.110 90 145 1.7E-15 T 13-10-2018 IPR036869 Chaperone J-domain superfamily Astex_3055 1fa9f300a48fadc780d3bb1d114e9391 146 SUPERFAMILY SSF46565 92 144 7.33E-13 T 13-10-2018 IPR036869 Chaperone J-domain superfamily Astex_1056 f50f6986f2b4589ea1418cd1983937ff 139 Pfam PF03960 ArsC family 6 112 1.3E-11 T 13-10-2018 IPR006660 Arsenate reductase-like Astex_1056 f50f6986f2b4589ea1418cd1983937ff 139 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 3 115 1.2E-34 T 13-10-2018 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 Astex_1056 f50f6986f2b4589ea1418cd1983937ff 139 Gene3D G3DSA:3.40.30.10 1 139 5.5E-49 T 13-10-2018 Astex_1056 f50f6986f2b4589ea1418cd1983937ff 139 SUPERFAMILY SSF52833 2 137 7.78E-32 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Astex_0093 1985179a05f8f8735137b4f323485125 192 SUPERFAMILY SSF56399 9 119 1.58E-12 T 13-10-2018 Astex_0601 0be8e03569dfe990a6fc8b606e226e68 156 Pfam PF14110 Domain of unknown function (DUF4282) 21 109 1.3E-18 T 13-10-2018 IPR025557 Protein of unknown function DUF4282 Astex_1654 0ace0e88ca290d07142a76e68b165308 158 Pfam PF00011 Hsp20/alpha crystallin family 51 145 3.5E-18 T 13-10-2018 IPR002068 Alpha crystallin/Hsp20 domain Astex_1654 0ace0e88ca290d07142a76e68b165308 158 SUPERFAMILY SSF49764 51 145 4.19E-19 T 13-10-2018 IPR008978 HSP20-like chaperone Astex_1654 0ace0e88ca290d07142a76e68b165308 158 Gene3D G3DSA:2.60.40.790 37 146 5.1E-21 T 13-10-2018 IPR008978 HSP20-like chaperone Astex_3223 2b31bf79c666a356a5343a7205ed7489 794 Pfam PF02687 FtsX-like permease family 317 401 9.3E-6 T 13-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 Astex_3223 2b31bf79c666a356a5343a7205ed7489 794 Pfam PF12704 MacB-like periplasmic core domain 23 242 5.4E-14 T 13-10-2018 IPR025857 MacB-like periplasmic core domain Astex_0652 1e9269ca663c895a5cd7eeb53741f1cd 67 Pfam PF11127 Protein of unknown function (DUF2892) 2 56 4.6E-13 T 13-10-2018 IPR021309 Protein of unknown function DUF2892 Astex_0026 aede79195b6ac5a2bc1d2e13f9092471 169 Pfam PF13508 Acetyltransferase (GNAT) domain 44 145 1.2E-8 T 13-10-2018 IPR000182 GNAT domain Astex_0026 aede79195b6ac5a2bc1d2e13f9092471 169 SUPERFAMILY SSF55729 15 149 4.43E-16 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Astex_0026 aede79195b6ac5a2bc1d2e13f9092471 169 Gene3D G3DSA:3.40.630.30 2 158 3.8E-39 T 13-10-2018 Astex_2522 903a4112c6aa6fe440a5b356aaf0ddd2 440 Gene3D G3DSA:3.90.1300.10 6 429 5.6E-114 T 13-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Astex_2522 903a4112c6aa6fe440a5b356aaf0ddd2 440 Pfam PF01425 Amidase 35 418 1.2E-81 T 13-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Astex_2522 903a4112c6aa6fe440a5b356aaf0ddd2 440 SUPERFAMILY SSF75304 6 428 1.2E-110 T 13-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 Astex_2522 903a4112c6aa6fe440a5b356aaf0ddd2 440 TIGRFAM TIGR02715 amido_AtzE: amidohydrolase, AtzE family 8 431 1.1E-158 T 13-10-2018 IPR014087 Amidohydrolase, AtzE type KEGG: 00791+3.5.1.84|MetaCyc: PWY-5169 Astex_1441 763b41158cc887ef666d8a9545985ab4 376 Pfam PF12698 ABC-2 family transporter protein 26 368 1.2E-49 T 13-10-2018 Astex_1967 a371f34aceac7138d61815c76e1d0aba 444 Gene3D G3DSA:3.90.226.10 189 424 5.0E-39 T 13-10-2018 Astex_1967 a371f34aceac7138d61815c76e1d0aba 444 Pfam PF03572 Peptidase family S41 247 421 1.1E-29 T 13-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 Astex_1967 a371f34aceac7138d61815c76e1d0aba 444 SMART SM00245 219 424 2.6E-8 T 13-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 Astex_1967 a371f34aceac7138d61815c76e1d0aba 444 SUPERFAMILY SSF52096 121 425 3.81E-40 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily Astex_1967 a371f34aceac7138d61815c76e1d0aba 444 Gene3D G3DSA:3.30.750.44 123 402 5.0E-39 T 13-10-2018 Astex_0484 dde05283f142755a013680968d25b6a8 306 Pfam PF01925 Sulfite exporter TauE/SafE 18 287 6.9E-45 T 13-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 Astex_0562 e1123024a3af36108c4c7fdd608eb1fe 118 Gene3D G3DSA:1.10.10.10 7 117 1.2E-31 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_0562 e1123024a3af36108c4c7fdd608eb1fe 118 Pfam PF03551 Transcriptional regulator PadR-like family 24 96 1.7E-21 T 13-10-2018 IPR005149 Transcription regulator PadR, N-terminal Astex_0562 e1123024a3af36108c4c7fdd608eb1fe 118 SUPERFAMILY SSF46785 10 109 1.34E-22 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_3671 ee6b11ebdfe2cfe0f5338a3f01a0023d 613 SUPERFAMILY SSF48208 253 368 1.53E-6 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 Astex_3236 7985d5b47bd8d289355cc5237e907da2 103 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 3 91 2.1E-8 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family Astex_3236 7985d5b47bd8d289355cc5237e907da2 103 Gene3D G3DSA:3.30.2310.20 1 97 1.3E-15 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Astex_1092 489154e6fd31c13206a8701b73ce2874 230 Pfam PF03458 UPF0126 domain 110 183 8.2E-20 T 13-10-2018 IPR005115 Uncharacterised domain UPF0126 Astex_1092 489154e6fd31c13206a8701b73ce2874 230 Pfam PF03458 UPF0126 domain 16 90 4.6E-18 T 13-10-2018 IPR005115 Uncharacterised domain UPF0126 Astex_2475 6bab49c139f94a0e0f157d72c4956dce 308 Gene3D G3DSA:3.40.1190.20 1 306 2.3E-91 T 13-10-2018 IPR029056 Ribokinase-like Astex_2475 6bab49c139f94a0e0f157d72c4956dce 308 PRINTS PR00990 Ribokinase signature 108 121 1.7E-29 T 13-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 Astex_2475 6bab49c139f94a0e0f157d72c4956dce 308 PRINTS PR00990 Ribokinase signature 176 191 1.7E-29 T 13-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 Astex_2475 6bab49c139f94a0e0f157d72c4956dce 308 PRINTS PR00990 Ribokinase signature 9 30 1.7E-29 T 13-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 Astex_2475 6bab49c139f94a0e0f157d72c4956dce 308 PRINTS PR00990 Ribokinase signature 220 231 1.7E-29 T 13-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 Astex_2475 6bab49c139f94a0e0f157d72c4956dce 308 PRINTS PR00990 Ribokinase signature 36 55 1.7E-29 T 13-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 Astex_2475 6bab49c139f94a0e0f157d72c4956dce 308 Pfam PF00294 pfkB family carbohydrate kinase 5 293 1.4E-65 T 13-10-2018 IPR011611 Carbohydrate kinase PfkB Astex_2475 6bab49c139f94a0e0f157d72c4956dce 308 SUPERFAMILY SSF53613 5 304 2.65E-76 T 13-10-2018 IPR029056 Ribokinase-like Astex_2475 6bab49c139f94a0e0f157d72c4956dce 308 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 41 65 - T 13-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 Astex_2475 6bab49c139f94a0e0f157d72c4956dce 308 Hamap MF_01987 Ribokinase [rbsK]. 5 303 23.257 T 13-10-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 Astex_0750 c30a37ff241e5d4ae7924f2d20a3c11f 648 Pfam PF13193 AMP-binding enzyme C-terminal domain 532 610 7.1E-24 T 13-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain Astex_0750 c30a37ff241e5d4ae7924f2d20a3c11f 648 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 7 646 49.504 T 13-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 Astex_0750 c30a37ff241e5d4ae7924f2d20a3c11f 648 ProSitePatterns PS00455 Putative AMP-binding domain signature. 262 273 - T 13-10-2018 IPR020845 AMP-binding, conserved site Astex_0750 c30a37ff241e5d4ae7924f2d20a3c11f 648 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 36 643 1.1E-289 T 13-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 Astex_0750 c30a37ff241e5d4ae7924f2d20a3c11f 648 SUPERFAMILY SSF56801 17 640 1.96E-172 T 13-10-2018 Astex_0750 c30a37ff241e5d4ae7924f2d20a3c11f 648 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 38 86 9.6E-12 T 13-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 Astex_0750 c30a37ff241e5d4ae7924f2d20a3c11f 648 Pfam PF00501 AMP-binding enzyme 92 523 2.4E-89 T 13-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 Astex_0750 c30a37ff241e5d4ae7924f2d20a3c11f 648 Gene3D G3DSA:3.30.300.30 519 646 2.5E-28 T 13-10-2018 Astex_0750 c30a37ff241e5d4ae7924f2d20a3c11f 648 Gene3D G3DSA:3.40.50.12780 55 516 8.0E-103 T 13-10-2018 Astex_0558 1eb661b80496d9ad60e803b2b1c35831 399 Pfam PF00872 Transposase, Mutator family 4 371 1.8E-125 T 13-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 Astex_2856 a8e2a3ff7e8580788901095091cec171 281 Gene3D G3DSA:3.40.140.80 130 279 2.3E-47 T 13-10-2018 Astex_2856 a8e2a3ff7e8580788901095091cec171 281 Gene3D G3DSA:3.40.50.20 1 128 4.6E-36 T 13-10-2018 Astex_2856 a8e2a3ff7e8580788901095091cec171 281 Pfam PF06230 Protein of unknown function (DUF1009) 56 272 2.3E-65 T 13-10-2018 IPR010415 Protein of unknown function DUF1009 KEGG: 00540+3.6.1.54 Astex_1688 ce43225c2d68ec612def63e6117cf472 116 SUPERFAMILY SSF103481 13 115 3.01E-5 T 13-10-2018 Astex_1688 ce43225c2d68ec612def63e6117cf472 116 Pfam PF04342 Putative member of DMT superfamily (DUF486) 10 113 7.2E-46 T 13-10-2018 IPR007437 Protein of unknown function DUF486 Astex_1688 ce43225c2d68ec612def63e6117cf472 116 PIRSF PIRSF021239 4 116 5.5E-50 T 13-10-2018 IPR007437 Protein of unknown function DUF486 Astex_0471 7a5bd2e601d42feb80bc2c0bf907e8fb 134 Pfam PF03610 PTS system fructose IIA component 3 115 4.0E-30 T 13-10-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 Astex_0471 7a5bd2e601d42feb80bc2c0bf907e8fb 134 Gene3D G3DSA:3.40.50.510 1 131 7.7E-39 T 13-10-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 Astex_0471 7a5bd2e601d42feb80bc2c0bf907e8fb 134 SUPERFAMILY SSF53062 1 130 1.57E-37 T 13-10-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 Astex_0703 01b51b90f7f6e952b24d087f951b57ee 344 Gene3D G3DSA:2.60.120.1660 3 282 1.2E-48 T 13-10-2018 Astex_0703 01b51b90f7f6e952b24d087f951b57ee 344 SMART SM00558 90 279 2.0E-4 T 13-10-2018 IPR003347 JmjC domain Astex_0703 01b51b90f7f6e952b24d087f951b57ee 344 SUPERFAMILY SSF51197 21 329 1.28E-52 T 13-10-2018 Astex_0703 01b51b90f7f6e952b24d087f951b57ee 344 Pfam PF13621 Cupin-like domain 21 267 1.1E-58 T 13-10-2018 Astex_0221 1931d6a3695ac364f31d029c1ee9077f 203 Pfam PF02630 SCO1/SenC 21 181 2.4E-40 T 13-10-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_0221 1931d6a3695ac364f31d029c1ee9077f 203 SUPERFAMILY SSF52833 43 202 8.34E-49 T 13-10-2018 IPR036249 Thioredoxin-like superfamily Astex_0221 1931d6a3695ac364f31d029c1ee9077f 203 Gene3D G3DSA:3.40.30.10 31 203 1.1E-53 T 13-10-2018 Astex_1623 46a1330f532cc4f9981373fad300ba68 432 PRINTS PR01035 Tetracycline resistance protein signature 312 333 1.3E-26 T 13-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Astex_1623 46a1330f532cc4f9981373fad300ba68 432 PRINTS PR01035 Tetracycline resistance protein signature 373 396 1.3E-26 T 13-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Astex_1623 46a1330f532cc4f9981373fad300ba68 432 PRINTS PR01035 Tetracycline resistance protein signature 111 135 1.3E-26 T 13-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Astex_1623 46a1330f532cc4f9981373fad300ba68 432 PRINTS PR01035 Tetracycline resistance protein signature 337 357 1.3E-26 T 13-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Astex_1623 46a1330f532cc4f9981373fad300ba68 432 PRINTS PR01035 Tetracycline resistance protein signature 54 70 1.3E-26 T 13-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Astex_1623 46a1330f532cc4f9981373fad300ba68 432 PRINTS PR01035 Tetracycline resistance protein signature 168 190 1.3E-26 T 13-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Astex_1623 46a1330f532cc4f9981373fad300ba68 432 PRINTS PR01035 Tetracycline resistance protein signature 138 159 1.3E-26 T 13-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Astex_1623 46a1330f532cc4f9981373fad300ba68 432 PRINTS PR01035 Tetracycline resistance protein signature 284 304 1.3E-26 T 13-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 Astex_1623 46a1330f532cc4f9981373fad300ba68 432 Gene3D G3DSA:1.20.1250.20 40 426 3.4E-81 T 13-10-2018 Astex_1623 46a1330f532cc4f9981373fad300ba68 432 SUPERFAMILY SSF103473 43 424 3.27E-75 T 13-10-2018 IPR036259 MFS transporter superfamily Astex_1623 46a1330f532cc4f9981373fad300ba68 432 Pfam PF07690 Major Facilitator Superfamily 49 279 2.7E-36 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Astex_3465 e2184ec6be86fbe3d847495cf7ff4c7c 187 Pfam PF11233 Protein of unknown function (DUF3035) 26 164 2.2E-30 T 13-10-2018 IPR021395 Protein of unknown function DUF3035 Astex_1186 4dd7db459f20e74baefc8afbb1872a75 166 Pfam PF13430 Domain of unknown function (DUF4112) 13 126 2.3E-17 T 13-10-2018 IPR025187 Protein of unknown function DUF4112 Astex_2840 90f0ac6827f813310e8d6ba477701519 427 Pfam PF12704 MacB-like periplasmic core domain 36 247 4.3E-15 T 13-10-2018 IPR025857 MacB-like periplasmic core domain Astex_2840 90f0ac6827f813310e8d6ba477701519 427 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 14 427 2.0E-125 T 13-10-2018 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 Astex_2840 90f0ac6827f813310e8d6ba477701519 427 Pfam PF02687 FtsX-like permease family 313 420 1.8E-9 T 13-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 Astex_2802 28ea85aceb7c38ebc0ef64015273c0f1 125 Gene3D G3DSA:1.20.58.1610 1 125 1.3E-40 T 13-10-2018 IPR038430 NADH:ubiquinone oxidoreductase, subunit 3 superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2802 28ea85aceb7c38ebc0ef64015273c0f1 125 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 24 124 1.2E-36 T 13-10-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2802 28ea85aceb7c38ebc0ef64015273c0f1 125 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 4 125 18.771 T 13-10-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 Astex_3166 2a458e78a4f034957aee5d19af55f247 462 Pfam PF12698 ABC-2 family transporter protein 20 437 6.8E-39 T 13-10-2018 Astex_1341 a5be51f073367936c78b6499e3ce8f9c 230 Pfam PF05275 Copper resistance protein B precursor (CopB) 38 230 1.3E-70 T 13-10-2018 IPR007939 Copper resistance B precursor GO:0005507|GO:0006878|GO:0009279 Astex_2736 f5c4a0f0a7434f019df7ed60876cbf78 256 Pfam PF03741 Integral membrane protein TerC family 17 217 3.3E-41 T 13-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 Astex_2736 f5c4a0f0a7434f019df7ed60876cbf78 256 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 15 217 3.3E-60 T 13-10-2018 IPR022301 Integral membrane protein YjbE Astex_1440 4e49d18e0c30844dd9098f143f7e1880 537 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 358 502 6.7E-28 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_1440 4e49d18e0c30844dd9098f143f7e1880 537 SUPERFAMILY SSF58104 266 531 2.44E-49 T 13-10-2018 Astex_1440 4e49d18e0c30844dd9098f143f7e1880 537 Gene3D G3DSA:1.10.287.950 258 537 4.6E-49 T 13-10-2018 Astex_1440 4e49d18e0c30844dd9098f143f7e1880 537 SMART SM00283 278 532 8.2E-44 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_1519 77f65f7e9461d5282a50912ea879e10b 271 SUPERFAMILY SSF53187 8 267 1.41E-71 T 13-10-2018 Astex_1519 77f65f7e9461d5282a50912ea879e10b 271 Gene3D G3DSA:3.40.630.40 3 270 1.7E-61 T 13-10-2018 Astex_1519 77f65f7e9461d5282a50912ea879e10b 271 Pfam PF05013 N-formylglutamate amidohydrolase 18 236 4.4E-55 T 13-10-2018 IPR007709 N-formylglutamate amidohydrolase Astex_1553 3192e48a74684cd108debc8c2d46951f 80 SUPERFAMILY SSF81469 8 48 2.09E-10 T 13-10-2018 IPR036596 Bacterial aa3 type cytochrome c oxidase subunit IV superfamily KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 Astex_1553 3192e48a74684cd108debc8c2d46951f 80 Pfam PF07835 Bacterial aa3 type cytochrome c oxidase subunit IV 9 48 4.7E-15 T 13-10-2018 IPR012422 Cytochrome c oxidase, subunit IV, bacterial aa3 type KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 Astex_1553 3192e48a74684cd108debc8c2d46951f 80 Gene3D G3DSA:1.20.5.160 7 49 6.5E-10 T 13-10-2018 IPR036596 Bacterial aa3 type cytochrome c oxidase subunit IV superfamily KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 Astex_1352 8880b8db210ea293d573c50f54f81b3f 68 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 3 49 1.9E-18 T 13-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 Astex_1352 8880b8db210ea293d573c50f54f81b3f 68 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 66 20.618 T 13-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 Astex_1352 8880b8db210ea293d573c50f54f81b3f 68 Pfam PF02416 mttA/Hcf106 family 4 53 1.8E-10 T 13-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 Astex_2556 ec3bc6594ffaa5dec2d3f5f42082c4c5 288 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 207 224 - T 13-10-2018 IPR000540 Flagellar motor protein MotA, conserved site Astex_2556 ec3bc6594ffaa5dec2d3f5f42082c4c5 288 TIGRFAM TIGR03818 MotA1: flagellar motor stator protein MotA 1 283 7.9E-110 T 13-10-2018 IPR022522 Flagellar motor stator, MotA Astex_2556 ec3bc6594ffaa5dec2d3f5f42082c4c5 288 Pfam PF01618 MotA/TolQ/ExbB proton channel family 136 237 5.7E-12 T 13-10-2018 IPR002898 MotA/TolQ/ExbB proton channel Astex_0428 855d8304408a88ffcd8695c7f02a0670 141 Pfam PF13629 Pilus formation protein N terminal region 25 94 1.3E-19 T 13-10-2018 IPR032789 Pilus formation protein, N-terminal Astex_0675 936a870457ab8d76aba6618179fe1c00 181 Gene3D G3DSA:1.20.120.450 3 173 1.7E-42 T 13-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes Astex_0675 936a870457ab8d76aba6618179fe1c00 181 SUPERFAMILY SSF109854 6 159 1.22E-33 T 13-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes Astex_0675 936a870457ab8d76aba6618179fe1c00 181 Pfam PF05163 DinB family 1 170 6.7E-28 T 13-10-2018 IPR007837 DNA damage-inducible protein DinB Astex_2852 806502b2b94c6de281016569a6ef970c 221 Pfam PF03938 Outer membrane protein (OmpH-like) 28 186 3.4E-20 T 13-10-2018 IPR005632 Chaperone protein Skp GO:0051082 Astex_2852 806502b2b94c6de281016569a6ef970c 221 SUPERFAMILY SSF111384 46 187 2.22E-22 T 13-10-2018 Astex_2852 806502b2b94c6de281016569a6ef970c 221 Gene3D G3DSA:3.30.910.20 38 219 2.0E-23 T 13-10-2018 IPR024930 Skp domain superfamily Astex_2852 806502b2b94c6de281016569a6ef970c 221 SMART SM00935 27 187 1.3E-22 T 13-10-2018 IPR005632 Chaperone protein Skp GO:0051082 Astex_2204 4242f83772db0ca08706ab531167c5d8 367 Pfam PF04230 Polysaccharide pyruvyl transferase 73 290 2.4E-11 T 13-10-2018 IPR007345 Polysaccharide pyruvyl transferase Astex_3052 08ece082007054453c6f80cb2500d9bf 144 TIGRFAM TIGR01841 phasin: phasin family protein 54 141 1.7E-13 T 13-10-2018 IPR010127 Phasin, subfamily 1 Astex_3052 08ece082007054453c6f80cb2500d9bf 144 Pfam PF09361 Phasin protein 35 133 6.4E-23 T 13-10-2018 IPR018968 Phasin Astex_2438 91e7e7785231dc75307c15fa35ca4de4 341 Pfam PF02371 Transposase IS116/IS110/IS902 family 214 287 2.3E-20 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 Astex_2438 91e7e7785231dc75307c15fa35ca4de4 341 Pfam PF01548 Transposase 6 151 2.7E-18 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 Astex_1425 91e7e7785231dc75307c15fa35ca4de4 341 Pfam PF02371 Transposase IS116/IS110/IS902 family 214 287 2.3E-20 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 Astex_1425 91e7e7785231dc75307c15fa35ca4de4 341 Pfam PF01548 Transposase 6 151 2.7E-18 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 Astex_1159 3bbf75c17bbb54a28034e463fa6edef6 266 Gene3D G3DSA:3.40.50.720 3 160 1.6E-28 T 13-10-2018 Astex_1159 3bbf75c17bbb54a28034e463fa6edef6 266 Gene3D G3DSA:1.10.3730.10 161 266 8.9E-35 T 13-10-2018 Astex_1159 3bbf75c17bbb54a28034e463fa6edef6 266 PIRSF PIRSF000193 3 266 2.4E-54 T 13-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 Astex_1159 3bbf75c17bbb54a28034e463fa6edef6 266 SUPERFAMILY SSF51735 4 147 5.5E-20 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_1159 3bbf75c17bbb54a28034e463fa6edef6 266 SUPERFAMILY SSF48179 158 266 8.84E-28 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 Astex_1159 3bbf75c17bbb54a28034e463fa6edef6 266 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 159 265 1.0E-29 T 13-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 Astex_1159 3bbf75c17bbb54a28034e463fa6edef6 266 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 6 99 1.7E-8 T 13-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal Astex_1159 3bbf75c17bbb54a28034e463fa6edef6 266 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 4 265 21.586 T 13-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 Astex_1159 3bbf75c17bbb54a28034e463fa6edef6 266 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 6 265 3.4E-61 T 13-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 Astex_1032 942b78f59f57565016f9e2ac659c313f 126 Pfam PF03203 MerC mercury resistance protein 14 121 2.4E-20 T 13-10-2018 IPR004891 Mercury transport protein MerC GO:0015097|GO:0015694|GO:0016020 Astex_1705 e7fa260f52a63a86c573af9335863596 192 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 6 188 35.263 T 13-10-2018 IPR004507 Flavin prenyltransferase UbiX-like Astex_1705 e7fa260f52a63a86c573af9335863596 192 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 7 186 1.7E-67 T 13-10-2018 IPR004507 Flavin prenyltransferase UbiX-like Astex_1705 e7fa260f52a63a86c573af9335863596 192 Pfam PF02441 Flavoprotein 7 168 1.5E-21 T 13-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 Astex_1705 e7fa260f52a63a86c573af9335863596 192 Gene3D G3DSA:3.40.50.1950 6 192 1.9E-71 T 13-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 Astex_1705 e7fa260f52a63a86c573af9335863596 192 SUPERFAMILY SSF52507 7 186 5.89E-57 T 13-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 Astex_1410 8caea96af3a9f9c660d385e1a9b23716 280 Pfam PF07103 Protein of unknown function (DUF1365) 6 250 7.3E-66 T 13-10-2018 IPR010775 Protein of unknown function DUF1365 Astex_3413 8c6b25ad1ccfc6b136098dcb4a130b21 226 Gene3D G3DSA:3.40.50.300 1 225 1.0E-68 T 13-10-2018 Astex_3413 8c6b25ad1ccfc6b136098dcb4a130b21 226 Pfam PF00005 ABC transporter 21 169 2.7E-34 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 Astex_3413 8c6b25ad1ccfc6b136098dcb4a130b21 226 SMART SM00382 30 217 2.8E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain Astex_3413 8c6b25ad1ccfc6b136098dcb4a130b21 226 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 Astex_3413 8c6b25ad1ccfc6b136098dcb4a130b21 226 SUPERFAMILY SSF52540 1 219 3.73E-70 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2053 993bbc4bc5eda7dbb708ccff486f9e1d 183 SUPERFAMILY SSF53335 52 139 7.96E-13 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Astex_2053 993bbc4bc5eda7dbb708ccff486f9e1d 183 Pfam PF08241 Methyltransferase domain 51 135 1.6E-6 T 13-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 Astex_2053 993bbc4bc5eda7dbb708ccff486f9e1d 183 Gene3D G3DSA:3.40.50.150 17 171 1.9E-11 T 13-10-2018 Astex_1070 cbcc845a19ec0d5b5e4deb958b684f5a 339 SUPERFAMILY SSF48537 24 232 6.67E-15 T 13-10-2018 IPR008947 Phospholipase C/P1 nuclease domain superfamily GO:0016788 Astex_1070 cbcc845a19ec0d5b5e4deb958b684f5a 339 Gene3D G3DSA:1.10.575.10 24 205 1.1E-5 T 13-10-2018 IPR008947 Phospholipase C/P1 nuclease domain superfamily GO:0016788 Astex_1237 15c8061c2a9f99a276e0c692157acccd 401 Pfam PF13372 Alginate export 52 255 6.5E-10 T 13-10-2018 IPR025388 Alginate export domain Astex_1029 53ce2ab2207bae148ef58a07cd3b3d1c 401 Pfam PF02687 FtsX-like permease family 304 391 6.1E-6 T 13-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 Astex_1762 58106d8194e7c6f98e4f325034dd6db9 145 Gene3D G3DSA:3.30.530.20 2 144 1.4E-9 T 13-10-2018 IPR023393 START-like domain superfamily Astex_1762 58106d8194e7c6f98e4f325034dd6db9 145 SUPERFAMILY SSF55961 1 143 1.06E-10 T 13-10-2018 Astex_1762 58106d8194e7c6f98e4f325034dd6db9 145 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 3 142 6.3E-7 T 13-10-2018 IPR019587 Polyketide cyclase/dehydrase Astex_0958 f077789ddb83ccff72e6e229268c20dc 101 Pfam PF00253 Ribosomal protein S14p/S29e 48 100 9.1E-26 T 13-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_0958 f077789ddb83ccff72e6e229268c20dc 101 SUPERFAMILY SSF57716 2 101 2.64E-35 T 13-10-2018 Astex_0958 f077789ddb83ccff72e6e229268c20dc 101 Gene3D G3DSA:4.10.830.10 43 101 2.2E-23 T 13-10-2018 Astex_0958 f077789ddb83ccff72e6e229268c20dc 101 ProSitePatterns PS00527 Ribosomal protein S14 signature. 63 85 - T 13-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0958 f077789ddb83ccff72e6e229268c20dc 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 26.55 T 13-10-2018 IPR023036 Ribosomal protein S14, bacterial/plastid Astex_2266 96efdbde4c9e48464528cb3b956566bf 351 Pfam PF08885 GSCFA family 39 308 3.1E-56 T 13-10-2018 IPR014982 GSCFA Astex_0183 989dfce0a74e654a73d96d0b3a04b0c5 400 Pfam PF04235 Protein of unknown function (DUF418) 226 390 1.1E-34 T 13-10-2018 IPR007349 Domain of unknown function DUF418 Astex_3250 29749a8822a5031e5f77c01132faf575 144 Pfam PF06676 Protein of unknown function (DUF1178) 1 133 9.8E-51 T 13-10-2018 IPR009562 Protein of unknown function DUF1178 Astex_3250 29749a8822a5031e5f77c01132faf575 144 PIRSF PIRSF032131 1 138 1.2E-52 T 13-10-2018 IPR009562 Protein of unknown function DUF1178 Astex_3765 e88b3bc2d0c4cef35033f2eb4d67e54e 89 SUPERFAMILY SSF89447 5 52 5.75E-7 T 13-10-2018 IPR037914 SpoVT-AbrB domain superfamily Astex_3765 e88b3bc2d0c4cef35033f2eb4d67e54e 89 Gene3D G3DSA:2.10.260.10 1 88 1.1E-9 T 13-10-2018 Astex_2486 a3daa1ee59ce45be482f0009aaa22d33 409 TIGRFAM TIGR02783 TrbL_P: P-type conjugative transfer protein TrbL 3 306 5.5E-62 T 13-10-2018 IPR014150 Conjugal transfer, TrbL Astex_2486 a3daa1ee59ce45be482f0009aaa22d33 409 Pfam PF04610 TrbL/VirB6 plasmid conjugal transfer protein 37 254 1.9E-49 T 13-10-2018 IPR007688 Plasmid conjugal transfer TrbL/VirB6 GO:0030255 Astex_0032 68e15d041a321afd65e1ee16cb825c59 71 Pfam PF03693 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH 2 52 7.9E-8 T 13-10-2018 IPR022789 Antitoxin ParD Astex_0032 68e15d041a321afd65e1ee16cb825c59 71 Gene3D G3DSA:1.10.8.1250 1 70 4.1E-8 T 13-10-2018 IPR038296 Antitoxin ParD superfamily Astex_0882 de21baaf90fb2551ed45a8866ecae387 383 Pfam PF04966 Carbohydrate-selective porin, OprB family 94 377 8.4E-34 T 13-10-2018 IPR007049 Carbohydrate-selective porin OprB GO:0008643|GO:0015288|GO:0016021 Astex_0882 de21baaf90fb2551ed45a8866ecae387 383 Gene3D G3DSA:2.40.160.180 19 378 2.5E-64 T 13-10-2018 IPR038673 Carbohydrate-selective porin OprB superfamily Astex_0549 67d4f88cc4a207e250f2b6889c86ad1a 50 TIGRFAM TIGR03510 XapX: XapX domain 4 45 8.8E-14 T 13-10-2018 IPR020017 XapX domain Astex_2674 ccfc8fb577a8370e37b0ae1f58996061 70 Pfam PF10038 Protein of unknown function (DUF2274) 1 63 3.5E-23 T 13-10-2018 IPR018733 Protein of unknown function DUF2274 Astex_1607 2737e9ab705da181375883795de84f26 410 Pfam PF01757 Acyltransferase family 25 349 6.2E-22 T 13-10-2018 IPR002656 Acyltransferase 3 GO:0016747 Astex_3660 08942281e84054f50a2fed7d09886738 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 2.0E-17 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Astex_3660 08942281e84054f50a2fed7d09886738 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 1.9E-9 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Astex_3660 08942281e84054f50a2fed7d09886738 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 1.9E-9 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 Astex_3660 08942281e84054f50a2fed7d09886738 206 SUPERFAMILY SSF46689 4 72 2.34E-17 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 Astex_3660 08942281e84054f50a2fed7d09886738 206 Gene3D G3DSA:1.10.357.10 4 205 8.9E-42 T 13-10-2018 Astex_0079 3d424d5eb18464924b57b2d0ddfbe8e7 145 Gene3D G3DSA:3.40.50.300 6 144 1.1E-35 T 13-10-2018 Astex_0079 3d424d5eb18464924b57b2d0ddfbe8e7 145 SUPERFAMILY SSF52540 27 120 8.56E-18 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0079 3d424d5eb18464924b57b2d0ddfbe8e7 145 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 14 133 1.4E-33 T 13-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 Astex_0079 3d424d5eb18464924b57b2d0ddfbe8e7 145 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 12 140 3.0E-29 T 13-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 Astex_2976 bf46133d33076a7e3dfd86642c3664cb 266 Gene3D G3DSA:3.40.50.1980 19 225 4.6E-13 T 13-10-2018 Astex_2976 bf46133d33076a7e3dfd86642c3664cb 266 SUPERFAMILY SSF53807 23 215 1.18E-19 T 13-10-2018 Astex_0423 81cbe5f1e4126873cc0c3682aaccd336 476 Pfam PF04972 BON domain 124 184 2.5E-6 T 13-10-2018 IPR007055 BON domain Astex_0423 81cbe5f1e4126873cc0c3682aaccd336 476 PRINTS PR00811 Bacterial general secretion pathway protein D signature 251 275 1.8E-6 T 13-10-2018 IPR001775 GspD/PilQ family Astex_0423 81cbe5f1e4126873cc0c3682aaccd336 476 PRINTS PR00811 Bacterial general secretion pathway protein D signature 188 198 1.8E-6 T 13-10-2018 IPR001775 GspD/PilQ family Astex_0423 81cbe5f1e4126873cc0c3682aaccd336 476 PRINTS PR00811 Bacterial general secretion pathway protein D signature 382 400 1.8E-6 T 13-10-2018 IPR001775 GspD/PilQ family Astex_0423 81cbe5f1e4126873cc0c3682aaccd336 476 PRINTS PR00811 Bacterial general secretion pathway protein D signature 405 419 1.8E-6 T 13-10-2018 IPR001775 GspD/PilQ family Astex_0423 81cbe5f1e4126873cc0c3682aaccd336 476 Pfam PF13629 Pilus formation protein N terminal region 51 119 8.1E-19 T 13-10-2018 IPR032789 Pilus formation protein, N-terminal Astex_0423 81cbe5f1e4126873cc0c3682aaccd336 476 Pfam PF00263 Bacterial type II and III secretion system protein 256 417 1.3E-37 T 13-10-2018 IPR004846 Type II/III secretion system GO:0009306 Astex_2072 6fc9f1440e8370a4d6c1febbcb865f77 408 ProSitePatterns PS01288 Uncharacterized protein family UPF0027 signature. 28 57 - T 13-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 Astex_2072 6fc9f1440e8370a4d6c1febbcb865f77 408 Gene3D G3DSA:3.90.1860.10 12 408 1.1E-116 T 13-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 Astex_2072 6fc9f1440e8370a4d6c1febbcb865f77 408 SUPERFAMILY SSF103365 11 408 2.75E-130 T 13-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 Astex_2072 6fc9f1440e8370a4d6c1febbcb865f77 408 Pfam PF01139 tRNA-splicing ligase RtcB 28 408 1.6E-129 T 13-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 Astex_2545 29d8adaaabc40eb04c3ba4fc2052825e 140 SUPERFAMILY SSF54637 22 138 1.07E-34 T 13-10-2018 IPR029069 HotDog domain superfamily Astex_2545 29d8adaaabc40eb04c3ba4fc2052825e 140 Gene3D G3DSA:3.10.129.10 8 140 9.3E-38 T 13-10-2018 Astex_2545 29d8adaaabc40eb04c3ba4fc2052825e 140 Pfam PF03061 Thioesterase superfamily 38 109 4.6E-17 T 13-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 Astex_1635 794e2723fabc4f081e41ea208368fb0c 266 Pfam PF09335 SNARE associated Golgi protein 99 214 1.4E-19 T 13-10-2018 IPR032816 SNARE associated Golgi protein Astex_0749 56d1ae3bb1eb69a121455a7ad335f2e1 256 SUPERFAMILY SSF102215 9 250 1.57E-66 T 13-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 Astex_0749 56d1ae3bb1eb69a121455a7ad335f2e1 256 Gene3D G3DSA:3.40.50.10310 4 253 1.4E-66 T 13-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 Astex_0749 56d1ae3bb1eb69a121455a7ad335f2e1 256 Pfam PF02633 Creatinine amidohydrolase 14 245 9.2E-57 T 13-10-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 Astex_2270 5eebc044a87b1a630ea961fcc1d931cb 268 SUPERFAMILY SSF51658 17 260 3.18E-36 T 13-10-2018 IPR036237 Xylose isomerase-like superfamily Astex_2270 5eebc044a87b1a630ea961fcc1d931cb 268 Gene3D G3DSA:3.20.20.150 1 262 7.7E-42 T 13-10-2018 Astex_2270 5eebc044a87b1a630ea961fcc1d931cb 268 Pfam PF01261 Xylose isomerase-like TIM barrel 20 212 1.0E-22 T 13-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain Astex_0442 002e2af07c31401dba26607dc1ea12b3 244 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 59 79 2.3E-56 T 13-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 Astex_0442 002e2af07c31401dba26607dc1ea12b3 244 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 153 179 2.3E-56 T 13-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 Astex_0442 002e2af07c31401dba26607dc1ea12b3 244 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 97 117 2.3E-56 T 13-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 Astex_0442 002e2af07c31401dba26607dc1ea12b3 244 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 118 138 2.3E-56 T 13-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 Astex_0442 002e2af07c31401dba26607dc1ea12b3 244 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 42 59 2.3E-56 T 13-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 Astex_0442 002e2af07c31401dba26607dc1ea12b3 244 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 201 225 2.3E-56 T 13-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 Astex_0442 002e2af07c31401dba26607dc1ea12b3 244 Pfam PF01578 Cytochrome C assembly protein 17 181 5.0E-33 T 13-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 Astex_0442 002e2af07c31401dba26607dc1ea12b3 244 TIGRFAM TIGR01191 ccmC: heme exporter protein CcmC 42 225 1.4E-79 T 13-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 Astex_2880 14f7b2838320b9275f9b324e4837fb41 447 SUPERFAMILY SSF51445 34 439 1.32E-51 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_2880 14f7b2838320b9275f9b324e4837fb41 447 Gene3D G3DSA:3.20.20.80 34 447 2.4E-113 T 13-10-2018 Astex_0822 8dd2ef866efd57a3f4eaa55bc1d24231 693 Pfam PF04185 Phosphoesterase family 45 430 2.7E-115 T 13-10-2018 IPR007312 Phosphoesterase GO:0016788 Astex_0822 8dd2ef866efd57a3f4eaa55bc1d24231 693 TIGRFAM TIGR03396 PC_PLC: phospholipase C, phosphocholine-specific 3 684 3.2E-243 T 13-10-2018 IPR017767 Bacterial phospholipase C, phosphocholine-specific GO:0034480 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 Astex_0822 8dd2ef866efd57a3f4eaa55bc1d24231 693 Gene3D G3DSA:3.40.720.10 242 509 5.8E-53 T 13-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 Astex_0822 8dd2ef866efd57a3f4eaa55bc1d24231 693 Gene3D G3DSA:3.40.720.10 35 214 5.7E-29 T 13-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 Astex_0822 8dd2ef866efd57a3f4eaa55bc1d24231 693 Pfam PF05506 Domain of unknown function (DUF756) 500 586 3.6E-9 T 13-10-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 Astex_2456 bad9818dc1d6dbc2110c6eedf23f4423 191 Pfam PF01464 Transglycosylase SLT domain 35 136 3.9E-18 T 13-10-2018 IPR008258 Transglycosylase SLT domain 1 Astex_2456 bad9818dc1d6dbc2110c6eedf23f4423 191 SUPERFAMILY SSF53955 21 156 3.64E-34 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily Astex_2456 bad9818dc1d6dbc2110c6eedf23f4423 191 Gene3D G3DSA:1.10.530.10 18 158 1.7E-31 T 13-10-2018 Astex_1270 324029f13c85213d401440c529cfa194 153 Gene3D G3DSA:3.40.630.30 3 153 1.1E-33 T 13-10-2018 Astex_1270 324029f13c85213d401440c529cfa194 153 SUPERFAMILY SSF55729 1 141 8.06E-21 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Astex_1270 324029f13c85213d401440c529cfa194 153 Pfam PF00583 Acetyltransferase (GNAT) family 45 131 4.5E-10 T 13-10-2018 IPR000182 GNAT domain Astex_1426 15db08d3acf0b1c963288de633df20ce 79 Pfam PF03693 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH 3 53 2.2E-13 T 13-10-2018 IPR022789 Antitoxin ParD Astex_1426 15db08d3acf0b1c963288de633df20ce 79 Gene3D G3DSA:1.10.8.1250 9 68 1.1E-12 T 13-10-2018 IPR038296 Antitoxin ParD superfamily Astex_1426 15db08d3acf0b1c963288de633df20ce 79 TIGRFAM TIGR02606 antidote_CC2985: putative addiction module antidote protein, CC2985 family 3 60 1.8E-16 T 13-10-2018 IPR022789 Antitoxin ParD Astex_1426 15db08d3acf0b1c963288de633df20ce 79 SUPERFAMILY SSF47598 2 40 3.89E-6 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 Astex_0408 29f6b620b3ecd16398e5f59aa2a19325 152 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 18 145 2.4E-45 T 13-10-2018 IPR003791 Protein of unknown function UPF0178 Astex_0408 29f6b620b3ecd16398e5f59aa2a19325 152 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 3 147 30.906 T 13-10-2018 IPR003791 Protein of unknown function UPF0178 Astex_1324 f295014cdcab13caf96177a60707bf67 357 SUPERFAMILY SSF53850 95 286 1.53E-9 T 13-10-2018 Astex_1324 f295014cdcab13caf96177a60707bf67 357 Gene3D G3DSA:3.40.190.10 24 335 7.8E-35 T 13-10-2018 Astex_1324 f295014cdcab13caf96177a60707bf67 357 Gene3D G3DSA:3.40.190.270 106 242 7.8E-35 T 13-10-2018 Astex_2008 d95e4db349c71ca38474bf0d79a6112e 177 Pfam PF13858 Protein of unknown function (DUF4199) 8 169 1.3E-22 T 13-10-2018 IPR025250 Protein of unknown function DUF4199 Astex_2335 12313d592a485e2afa8f13576b2b91e5 487 SUPERFAMILY SSF58104 217 480 8.11E-55 T 13-10-2018 Astex_2335 12313d592a485e2afa8f13576b2b91e5 487 Gene3D G3DSA:1.10.287.950 198 481 1.3E-51 T 13-10-2018 Astex_2335 12313d592a485e2afa8f13576b2b91e5 487 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 291 449 1.8E-29 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_2335 12313d592a485e2afa8f13576b2b91e5 487 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 354 383 2.1E-20 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_2335 12313d592a485e2afa8f13576b2b91e5 487 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 244 273 2.1E-20 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_2335 12313d592a485e2afa8f13576b2b91e5 487 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 325 352 2.1E-20 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_2335 12313d592a485e2afa8f13576b2b91e5 487 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 402 431 2.1E-20 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 Astex_2335 12313d592a485e2afa8f13576b2b91e5 487 SMART SM00283 227 481 2.1E-35 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 Astex_0732 885e6ebb4c54d2f4ac67811a89669c9e 461 Pfam PF04434 SWIM zinc finger 65 82 2.4E-4 T 13-10-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 Astex_3387 3de12d0b5bf559f8b4e6dedba224545c 141 Gene3D G3DSA:1.10.10.1550 55 111 7.7E-32 T 13-10-2018 Astex_3387 3de12d0b5bf559f8b4e6dedba224545c 141 Pfam PF05443 ROS/MUCR transcriptional regulator protein 7 128 8.1E-52 T 13-10-2018 IPR008807 ROSMUCR transcriptional regulator GO:0003677|GO:0006355|GO:0008270 Astex_2513 7a834f26cd9a7746aee48df5a6e8d85e 523 SMART SM00813 321 516 3.2E-71 T 13-10-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 Astex_2513 7a834f26cd9a7746aee48df5a6e8d85e 523 Pfam PF06964 Alpha-L-arabinofuranosidase C-terminal domain 321 516 3.4E-37 T 13-10-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 Astex_2513 7a834f26cd9a7746aee48df5a6e8d85e 523 Gene3D G3DSA:2.60.40.1180 40 520 1.4E-179 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta Astex_2513 7a834f26cd9a7746aee48df5a6e8d85e 523 SUPERFAMILY SSF51445 41 402 6.47E-91 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily Astex_2513 7a834f26cd9a7746aee48df5a6e8d85e 523 SUPERFAMILY SSF51011 389 522 1.65E-22 T 13-10-2018 Astex_2513 7a834f26cd9a7746aee48df5a6e8d85e 523 Gene3D G3DSA:3.20.20.80 42 403 1.4E-179 T 13-10-2018 Astex_2079 76a71124cabdba2de7510640da5fdbb4 256 Pfam PF11459 Transcriptional regulator, AbiEi antitoxin, Type IV TA system 99 249 1.7E-53 T 13-10-2018 IPR021561 Transcriptional regulator, AbiEi 3 antitoxin, Type IV TA system Astex_2079 76a71124cabdba2de7510640da5fdbb4 256 Pfam PF17194 Transcriptional regulator, AbiEi antitoxin N-terminal domain 6 96 3.9E-36 T 13-10-2018 IPR033455 Transcriptional regulator AbiEi antitoxin, N-terminal domain Astex_1757 126a5e25a17ce0e66d5b57c949f39ca9 331 SUPERFAMILY SSF53448 38 311 3.31E-46 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_1757 126a5e25a17ce0e66d5b57c949f39ca9 331 Gene3D G3DSA:3.90.550.10 35 274 8.6E-45 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_1757 126a5e25a17ce0e66d5b57c949f39ca9 331 Pfam PF13641 Glycosyltransferase like family 2 42 271 5.3E-17 T 13-10-2018 Astex_0977 026f0b1be74e5f078341c3848026aed8 149 Pfam PF06210 Protein of unknown function (DUF1003) 29 123 2.8E-36 T 13-10-2018 IPR010406 Protein of unknown function DUF1003 Astex_1460 71d99ad7250d62cf61c1f0f396b0a850 434 SUPERFAMILY SSF56935 74 415 4.12E-18 T 13-10-2018 Astex_0139 b95ef51d047ea193a8265eaa1a8ba86a 214 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 23 189 6.0E-32 T 13-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 Astex_0139 b95ef51d047ea193a8265eaa1a8ba86a 214 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 11 205 24.125 T 13-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 Astex_0139 b95ef51d047ea193a8265eaa1a8ba86a 214 SUPERFAMILY SSF53335 8 190 1.76E-26 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Astex_0139 b95ef51d047ea193a8265eaa1a8ba86a 214 PIRSF PIRSF003078 2 209 9.4E-43 T 13-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 Astex_0139 b95ef51d047ea193a8265eaa1a8ba86a 214 Pfam PF02527 rRNA small subunit methyltransferase G 20 192 9.8E-40 T 13-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 Astex_0139 b95ef51d047ea193a8265eaa1a8ba86a 214 Gene3D G3DSA:3.40.50.150 2 210 2.9E-47 T 13-10-2018 Astex_3659 492b27396ec6fc81c3e2e1be6ef3ee1d 415 Pfam PF07804 HipA-like C-terminal domain 172 383 5.0E-45 T 13-10-2018 IPR012893 HipA-like, C-terminal Astex_2214 ed028a9f7fb33ac126d231a69f5e910b 330 SUPERFAMILY SSF51735 1 319 1.97E-65 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_2214 ed028a9f7fb33ac126d231a69f5e910b 330 Gene3D G3DSA:3.40.50.720 1 324 1.7E-70 T 13-10-2018 Astex_2214 ed028a9f7fb33ac126d231a69f5e910b 330 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 250 1.2E-41 T 13-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 Astex_0222 0b8f1fc4dd848c009c9571b0e6d1616b 196 SUPERFAMILY SSF159888 8 125 3.92E-19 T 13-10-2018 Astex_0222 0b8f1fc4dd848c009c9571b0e6d1616b 196 Pfam PF13376 Bacteriocin-protection, YdeI or OmpD-Associated 133 191 1.8E-17 T 13-10-2018 Astex_0222 0b8f1fc4dd848c009c9571b0e6d1616b 196 PIRSF PIRSF021308 1 196 5.0E-79 T 13-10-2018 IPR016786 Uncharacterised protein YdeI, bacterial Astex_0222 0b8f1fc4dd848c009c9571b0e6d1616b 196 Pfam PF08818 Domain of unknown function (DU1801) 19 116 3.6E-16 T 13-10-2018 IPR014922 Domain of unknown function DUF1801 Astex_1037 cdaeb9c4b9924aa083c9e6d4f7116b9c 451 Pfam PF12040 Domain of unknown function (DUF3526) 278 416 8.4E-31 T 13-10-2018 IPR021913 Protein of unknown function DUF3526 Astex_3144 2d645cde629af87dddf7480fc7cd04ad 382 Pfam PF04339 Peptidogalycan biosysnthesis/recognition 13 377 1.8E-145 T 13-10-2018 IPR007434 Peptidogalycan biosysnthesis/recognition Astex_3144 2d645cde629af87dddf7480fc7cd04ad 382 SUPERFAMILY SSF55729 180 344 4.13E-37 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Astex_0751 ccef3a44c657a42f41dce73790a1751e 149 Pfam PF01814 Hemerythrin HHE cation binding domain 3 121 3.5E-12 T 13-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 Astex_0751 ccef3a44c657a42f41dce73790a1751e 149 Gene3D G3DSA:1.20.120.520 1 143 9.9E-10 T 13-10-2018 Astex_0943 fec0e026b75fa44111e20a74e7726127 396 Pfam PF13480 Acetyltransferase (GNAT) domain 158 306 2.0E-25 T 13-10-2018 IPR038740 BioF2-like, acetyltransferase domain KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 Astex_0943 fec0e026b75fa44111e20a74e7726127 396 SUPERFAMILY SSF55729 168 310 5.83E-13 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Astex_2026 c8dc793b1e1b367551a2b28fea4339eb 435 Gene3D G3DSA:1.25.40.10 311 433 2.5E-5 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_3712 8d1541cda6fa92939986b1ab4aa58316 250 SUPERFAMILY SSF53927 91 210 2.82E-6 T 13-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 Astex_0908 1a8eb8f1794c7ddb52610a020f2e0aeb 136 SUPERFAMILY SSF54637 3 132 5.87E-9 T 13-10-2018 IPR029069 HotDog domain superfamily Astex_1024 9f902bbc53c85f906ef8c50fe8dd115f 151 Pfam PF04120 Low affinity iron permease 16 139 6.0E-53 T 13-10-2018 IPR007251 Low affinity iron permease, Fet4 GO:0055085 Astex_0335 08ebeba7e6ee6848fb4441ff2b5779b1 112 Gene3D G3DSA:2.40.10.270 3 109 1.5E-8 T 13-10-2018 IPR038666 Bacteriophage SPP1, head-tail adaptor superfamily Astex_0335 08ebeba7e6ee6848fb4441ff2b5779b1 112 Pfam PF05521 Phage head-tail joining protein 10 103 5.8E-11 T 13-10-2018 IPR008767 Bacteriophage SPP1, head-tail adaptor Astex_3512 aac02f748a939c7cd8d805b85975560a 674 SUPERFAMILY SSF56935 25 643 2.88E-33 T 13-10-2018 Astex_3512 aac02f748a939c7cd8d805b85975560a 674 Pfam PF07715 TonB-dependent Receptor Plug Domain 26 114 3.5E-5 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_3512 aac02f748a939c7cd8d805b85975560a 674 Pfam PF00593 TonB dependent receptor 220 646 9.2E-10 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel Astex_3512 aac02f748a939c7cd8d805b85975560a 674 Gene3D G3DSA:2.40.170.20 227 646 3.9E-11 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_3512 aac02f748a939c7cd8d805b85975560a 674 Gene3D G3DSA:2.170.130.10 18 134 1.4E-5 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_1293 21111dc8a879e5bd69e53598b5b9da91 206 Pfam PF16357 Putative PepSY_TM-like 12 205 2.8E-70 T 13-10-2018 IPR032307 Putative PepSY TM-like protein Astex_2621 87107e08f486da41d721bc5c8601c7e5 123 Pfam PF06170 Protein of unknown function (DUF983) 28 111 5.0E-30 T 13-10-2018 IPR009325 Protein of unknown function DUF983 Astex_1075 2e2fb8d485803399c91960941b71cbb5 212 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 128 141 - T 13-10-2018 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 Astex_1075 2e2fb8d485803399c91960941b71cbb5 212 SUPERFAMILY SSF51569 5 207 1.81E-54 T 13-10-2018 Astex_1075 2e2fb8d485803399c91960941b71cbb5 212 Gene3D G3DSA:3.20.20.70 10 211 2.5E-59 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_1075 2e2fb8d485803399c91960941b71cbb5 212 Pfam PF01081 KDPG and KHG aldolase 9 186 1.6E-26 T 13-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 Astex_1160 9e6740bedc7619890b6afd882736d8ad 365 SUPERFAMILY SSF50956 46 364 2.22E-51 T 13-10-2018 Astex_1160 9e6740bedc7619890b6afd882736d8ad 365 Pfam PF02333 Phytase 35 362 9.8E-64 T 13-10-2018 IPR003431 Beta propeller phytase GO:0016158 KEGG: 00562+3.1.3.8|MetaCyc: PWY-4702 Astex_1160 9e6740bedc7619890b6afd882736d8ad 365 Gene3D G3DSA:2.120.10.30 38 365 2.1E-90 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like Astex_0967 e536d59ebd968518a604c3acbaaa7460 122 Pfam PF00416 Ribosomal protein S13/S18 3 109 1.6E-31 T 13-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0967 e536d59ebd968518a604c3acbaaa7460 122 PIRSF PIRSF002134 1 122 8.8E-45 T 13-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0967 e536d59ebd968518a604c3acbaaa7460 122 Gene3D G3DSA:4.10.910.10 73 119 7.9E-27 T 13-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0967 e536d59ebd968518a604c3acbaaa7460 122 ProSitePatterns PS00646 Ribosomal protein S13 signature. 88 101 - T 13-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0967 e536d59ebd968518a604c3acbaaa7460 122 Gene3D G3DSA:1.10.8.50 1 72 3.6E-28 T 13-10-2018 Astex_0967 e536d59ebd968518a604c3acbaaa7460 122 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 115 2.9E-53 T 13-10-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Astex_0967 e536d59ebd968518a604c3acbaaa7460 122 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 119 27.207 T 13-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 Astex_0967 e536d59ebd968518a604c3acbaaa7460 122 SUPERFAMILY SSF46946 2 121 3.92E-45 T 13-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 Astex_3584 2a34e8fd03a0ab0d70c4bb245705c742 147 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 49 122 1.5E-15 T 13-10-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 Astex_3584 2a34e8fd03a0ab0d70c4bb245705c742 147 TIGRFAM TIGR02847 CyoD: cytochrome o ubiquinol oxidase subunit IV 42 136 3.9E-33 T 13-10-2018 IPR014210 Cytochrome o ubiquinol oxidase subunit IV GO:0008827|GO:0015990|GO:0016021 Astex_3388 e792b24d56c9fb4ae25ecaa583a0b2cc 369 Pfam PF16670 Phosphoinositide phospholipase C, Ca2+-dependent 37 361 2.9E-125 T 13-10-2018 IPR032075 Phosphoinositide phospholipase C, Ca2+-dependent Astex_3388 e792b24d56c9fb4ae25ecaa583a0b2cc 369 Gene3D G3DSA:3.20.20.190 72 343 5.8E-42 T 13-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 Astex_3388 e792b24d56c9fb4ae25ecaa583a0b2cc 369 SUPERFAMILY SSF51695 36 347 7.85E-21 T 13-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 Astex_0024 f1d8b5cac5d62193bd25421120f45d1c 528 Pfam PF03023 MviN-like protein 39 474 5.1E-97 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ Astex_0024 f1d8b5cac5d62193bd25421120f45d1c 528 Hamap MF_02078 Probable lipid II flippase MurJ [murJ]. 12 476 17.681 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ Astex_0024 f1d8b5cac5d62193bd25421120f45d1c 528 PIRSF PIRSF002869 7 527 2.9E-129 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ Astex_0024 f1d8b5cac5d62193bd25421120f45d1c 528 PRINTS PR01806 Virulence factor MviN signature 63 79 2.2E-61 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ Astex_0024 f1d8b5cac5d62193bd25421120f45d1c 528 PRINTS PR01806 Virulence factor MviN signature 144 168 2.2E-61 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ Astex_0024 f1d8b5cac5d62193bd25421120f45d1c 528 PRINTS PR01806 Virulence factor MviN signature 366 385 2.2E-61 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ Astex_0024 f1d8b5cac5d62193bd25421120f45d1c 528 PRINTS PR01806 Virulence factor MviN signature 44 63 2.2E-61 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ Astex_0024 f1d8b5cac5d62193bd25421120f45d1c 528 PRINTS PR01806 Virulence factor MviN signature 168 189 2.2E-61 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ Astex_0024 f1d8b5cac5d62193bd25421120f45d1c 528 PRINTS PR01806 Virulence factor MviN signature 268 294 2.2E-61 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ Astex_0024 f1d8b5cac5d62193bd25421120f45d1c 528 PRINTS PR01806 Virulence factor MviN signature 418 435 2.2E-61 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ Astex_0024 f1d8b5cac5d62193bd25421120f45d1c 528 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 11 514 3.0E-113 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ Astex_1576 7695235954ae8c591d925498b1f89142 298 Pfam PF10098 Uncharacterised protein conserved in bacteria (DUF2336) 68 181 6.5E-20 T 13-10-2018 IPR019285 Protein of unknown function DUF2336 Astex_1576 7695235954ae8c591d925498b1f89142 298 Pfam PF10098 Uncharacterised protein conserved in bacteria (DUF2336) 197 289 1.0E-9 T 13-10-2018 IPR019285 Protein of unknown function DUF2336 Astex_3281 af0b2fcc2b07a0101507455fa3fc8b3e 794 SUPERFAMILY SSF56935 67 716 5.9E-59 T 13-10-2018 Astex_3281 af0b2fcc2b07a0101507455fa3fc8b3e 794 Pfam PF07715 TonB-dependent Receptor Plug Domain 91 174 1.8E-11 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain Astex_3281 af0b2fcc2b07a0101507455fa3fc8b3e 794 Gene3D G3DSA:2.40.170.20 222 644 4.3E-22 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Astex_3281 af0b2fcc2b07a0101507455fa3fc8b3e 794 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 74 - T 13-10-2018 IPR010916 TonB box, conserved site Astex_3281 af0b2fcc2b07a0101507455fa3fc8b3e 794 Gene3D G3DSA:2.170.130.10 76 181 4.4E-14 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily Astex_3281 af0b2fcc2b07a0101507455fa3fc8b3e 794 Pfam PF14905 Outer membrane protein beta-barrel family 333 736 5.3E-47 T 13-10-2018 Astex_3076 141d97e9bc787577724903c89354a875 534 Gene3D G3DSA:1.25.40.10 304 439 2.5E-11 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_3076 141d97e9bc787577724903c89354a875 534 SUPERFAMILY SSF48452 329 431 3.21E-11 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_0755 01ef565923656588d5ac8620760ace21 152 Pfam PF03994 Domain of Unknown Function (DUF350) 36 86 6.2E-13 T 13-10-2018 IPR007140 Protein of unknown function DUF350 Astex_0755 01ef565923656588d5ac8620760ace21 152 Pfam PF03994 Domain of Unknown Function (DUF350) 98 150 1.4E-9 T 13-10-2018 IPR007140 Protein of unknown function DUF350 Astex_1459 5872733bcfc560f147133d4b44d6edf2 428 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 30 102 1.2E-18 T 13-10-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 Astex_1459 5872733bcfc560f147133d4b44d6edf2 428 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 215 425 8.6E-70 T 13-10-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 Astex_2328 7564a01e231f0c6876e97dc5981e1442 260 Gene3D G3DSA:3.40.50.2300 125 258 3.2E-26 T 13-10-2018 Astex_2328 7564a01e231f0c6876e97dc5981e1442 260 SMART SM00448 131 247 1.1E-16 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_2328 7564a01e231f0c6876e97dc5981e1442 260 SMART SM00448 2 117 6.3E-8 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_2328 7564a01e231f0c6876e97dc5981e1442 260 Pfam PF00072 Response regulator receiver domain 5 115 4.4E-12 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_2328 7564a01e231f0c6876e97dc5981e1442 260 Pfam PF00072 Response regulator receiver domain 133 247 4.5E-19 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_2328 7564a01e231f0c6876e97dc5981e1442 260 Gene3D G3DSA:3.40.50.2300 2 124 4.7E-18 T 13-10-2018 Astex_2328 7564a01e231f0c6876e97dc5981e1442 260 SUPERFAMILY SSF52172 3 122 1.99E-19 T 13-10-2018 IPR011006 CheY-like superfamily Astex_2328 7564a01e231f0c6876e97dc5981e1442 260 SUPERFAMILY SSF52172 130 253 1.85E-27 T 13-10-2018 IPR011006 CheY-like superfamily Astex_2269 74075bd7f5760ea30d8b6f84b050ba17 367 Pfam PF04577 Protein of unknown function (DUF563) 180 334 4.9E-22 T 13-10-2018 IPR007657 Glycosyltransferase 61 GO:0016757 Astex_2391 967da2dd5d62840cbfa8387bd86f38f6 171 Gene3D G3DSA:3.30.530.20 1 167 6.5E-60 T 13-10-2018 IPR023393 START-like domain superfamily Astex_2391 967da2dd5d62840cbfa8387bd86f38f6 171 SUPERFAMILY SSF55961 28 166 4.2E-9 T 13-10-2018 Astex_3564 6bcef17cadd89b199c2b97c56da4a36f 268 SUPERFAMILY SSF52540 25 208 3.21E-20 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_3564 6bcef17cadd89b199c2b97c56da4a36f 268 Pfam PF03308 ArgK protein 11 62 1.6E-6 T 13-10-2018 Astex_3564 6bcef17cadd89b199c2b97c56da4a36f 268 Gene3D G3DSA:3.40.50.300 8 268 9.1E-59 T 13-10-2018 Astex_2174 6d676296db557ba84654a45ffde9904d 160 Gene3D G3DSA:1.10.260.40 6 76 1.8E-12 T 13-10-2018 Astex_2174 6d676296db557ba84654a45ffde9904d 160 Pfam PF13560 Helix-turn-helix domain 12 66 7.4E-7 T 13-10-2018 Astex_2174 6d676296db557ba84654a45ffde9904d 160 SUPERFAMILY SSF47413 9 69 1.27E-8 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Astex_0864 be3a34163001854fb22f81ed52ce7f5b 351 Pfam PF00953 Glycosyl transferase family 4 81 236 9.3E-22 T 13-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 Astex_2032 3948f4776855b57224168c56329594c1 298 Pfam PF00682 HMGL-like 7 278 1.2E-51 T 13-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 Astex_2032 3948f4776855b57224168c56329594c1 298 Gene3D G3DSA:3.20.20.70 1 297 4.0E-131 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 Astex_2032 3948f4776855b57224168c56329594c1 298 SUPERFAMILY SSF51569 3 294 8.06E-73 T 13-10-2018 Astex_0100 283d43f2aad3541c12eb685e082d06f4 169 Pfam PF04073 Aminoacyl-tRNA editing domain 45 151 1.6E-23 T 13-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 Astex_0100 283d43f2aad3541c12eb685e082d06f4 169 Gene3D G3DSA:3.90.960.10 2 169 5.0E-43 T 13-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 Astex_0100 283d43f2aad3541c12eb685e082d06f4 169 SUPERFAMILY SSF55826 9 167 1.1E-37 T 13-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 Astex_2479 40875e72a21454127eae63dc5106a3a2 701 Pfam PF02534 Type IV secretory system Conjugative DNA transfer 112 565 8.3E-104 T 13-10-2018 IPR003688 Type IV secretion system protein TraG/VirD4 GO:0009291|GO:0016020 Astex_2479 40875e72a21454127eae63dc5106a3a2 701 SUPERFAMILY SSF52540 105 558 3.66E-47 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_2479 40875e72a21454127eae63dc5106a3a2 701 Gene3D G3DSA:3.40.50.300 330 561 4.9E-50 T 13-10-2018 Astex_0793 cff164a0b748f43072b954da398734c0 261 Pfam PF07719 Tetratricopeptide repeat 209 242 1.1E-6 T 13-10-2018 IPR013105 Tetratricopeptide repeat 2 Astex_0793 cff164a0b748f43072b954da398734c0 261 SUPERFAMILY SSF48452 134 256 4.09E-14 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_0793 cff164a0b748f43072b954da398734c0 261 Gene3D G3DSA:1.25.40.10 120 260 1.3E-14 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_0793 cff164a0b748f43072b954da398734c0 261 SMART SM00028 209 242 8.8E-5 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Astex_0793 cff164a0b748f43072b954da398734c0 261 SMART SM00028 135 168 30.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 Astex_0133 22c2890b7cf2a8df475b8b56d15378c5 164 Pfam PF12100 Domain of unknown function (DUF3576) 60 159 4.0E-47 T 13-10-2018 IPR021959 Protein of unknown function DUF3576 Astex_2268 57e5bc2fd1faa9a45a6d9596fbb01acc 244 SUPERFAMILY SSF53335 44 218 5.29E-17 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Astex_2268 57e5bc2fd1faa9a45a6d9596fbb01acc 244 Gene3D G3DSA:3.40.50.150 38 202 3.9E-13 T 13-10-2018 Astex_2268 57e5bc2fd1faa9a45a6d9596fbb01acc 244 Pfam PF08241 Methyltransferase domain 57 150 4.2E-7 T 13-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 Astex_3001 2d530e10a3e500c21ce2f25c2f7834df 76 Gene3D G3DSA:2.10.260.10 1 38 4.7E-14 T 13-10-2018 Astex_3001 2d530e10a3e500c21ce2f25c2f7834df 76 SMART SM00966 4 50 1.7E-9 T 13-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 Astex_3001 2d530e10a3e500c21ce2f25c2f7834df 76 SUPERFAMILY SSF89447 1 57 4.88E-13 T 13-10-2018 IPR037914 SpoVT-AbrB domain superfamily Astex_3001 2d530e10a3e500c21ce2f25c2f7834df 76 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 5 37 1.8E-12 T 13-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 Astex_0279 353cf3ac2bee43f6510129c3ac20d2a9 163 SUPERFAMILY SSF46785 5 136 4.75E-30 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_0279 353cf3ac2bee43f6510129c3ac20d2a9 163 Pfam PF02082 Transcriptional regulator 1 81 8.8E-23 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type Astex_0279 353cf3ac2bee43f6510129c3ac20d2a9 163 Gene3D G3DSA:1.10.10.10 2 144 1.0E-40 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_0049 2a6c0a85ace5e6a66f6c8ccc338d8137 69 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 7 67 8.5E-16 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 Astex_0049 2a6c0a85ace5e6a66f6c8ccc338d8137 69 Gene3D G3DSA:1.10.260.40 7 66 1.5E-7 T 13-10-2018 Astex_0049 2a6c0a85ace5e6a66f6c8ccc338d8137 69 SUPERFAMILY SSF47413 3 68 7.82E-10 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Astex_2422 7e1d3f4f7f239d30251c987520257121 363 Gene3D G3DSA:3.40.710.10 38 339 7.2E-59 T 13-10-2018 Astex_2422 7e1d3f4f7f239d30251c987520257121 363 Pfam PF00144 Beta-lactamase 39 335 1.4E-43 T 13-10-2018 IPR001466 Beta-lactamase-related Astex_2422 7e1d3f4f7f239d30251c987520257121 363 SUPERFAMILY SSF56601 40 343 2.39E-58 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like Astex_1057 3f0a117fc2abcc030853a3a23b086107 242 SUPERFAMILY SSF52218 7 229 5.82E-64 T 13-10-2018 IPR029039 Flavoprotein-like superfamily Astex_1057 3f0a117fc2abcc030853a3a23b086107 242 Pfam PF03358 NADPH-dependent FMN reductase 36 179 7.6E-26 T 13-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 Astex_1057 3f0a117fc2abcc030853a3a23b086107 242 Gene3D G3DSA:3.40.50.360 1 242 6.5E-77 T 13-10-2018 IPR029039 Flavoprotein-like superfamily Astex_1057 3f0a117fc2abcc030853a3a23b086107 242 TIGRFAM TIGR02690 resist_ArsH: arsenical resistance protein ArsH 10 228 3.1E-125 T 13-10-2018 IPR014063 Arsenate resistance ArsH Astex_1900 b358b03d93b7afaec7639880d26adff5 284 Gene3D G3DSA:3.20.20.140 2 283 3.1E-85 T 13-10-2018 Astex_1900 b358b03d93b7afaec7639880d26adff5 284 Pfam PF04909 Amidohydrolase 5 280 2.1E-38 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 Astex_1900 b358b03d93b7afaec7639880d26adff5 284 SUPERFAMILY SSF51556 4 280 2.04E-61 T 13-10-2018 IPR032466 Metal-dependent hydrolase Astex_1598 c6d98fdbea0d6461c791d8692aab12fe 61 Pfam PF04324 BFD-like [2Fe-2S] binding domain 2 50 8.0E-9 T 13-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain Astex_1598 c6d98fdbea0d6461c791d8692aab12fe 61 Gene3D G3DSA:1.10.10.1100 1 56 4.4E-12 T 13-10-2018 Astex_0232 6374eb72acec710f51f80aaa7cc71161 285 Pfam PF04397 LytTr DNA-binding domain 196 281 4.2E-17 T 13-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 Astex_0232 6374eb72acec710f51f80aaa7cc71161 285 SMART SM00850 188 284 1.7E-16 T 13-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 Astex_0748 511326f704fdc3407d2575de16ab9f9d 111 Gene3D G3DSA:2.102.10.10 6 111 7.5E-10 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 Astex_0748 511326f704fdc3407d2575de16ab9f9d 111 Pfam PF00355 Rieske [2Fe-2S] domain 29 94 8.7E-8 T 13-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 Astex_0748 511326f704fdc3407d2575de16ab9f9d 111 SUPERFAMILY SSF50022 8 109 4.58E-15 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 Astex_2062 c9af8dcd46f089bc00b2f707cc8d9c01 147 SUPERFAMILY SSF50891 36 146 6.07E-23 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily Astex_2062 c9af8dcd46f089bc00b2f707cc8d9c01 147 Gene3D G3DSA:2.40.100.20 36 147 5.2E-15 T 13-10-2018 Astex_3173 8027e186c25ac932510d430bb459ee9a 146 Pfam PF05433 Glycine zipper 2TM domain 44 83 5.3E-11 T 13-10-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 Astex_3701 64c97b174344b4613ed37728d3a2f46d 248 Pfam PF09836 Putative DNA-binding domain 6 86 5.0E-20 T 13-10-2018 IPR018640 Putative DNA-binding domain, bacteria Astex_0514 0a6f84be98194262d47465d0497e4ec1 309 Pfam PF00535 Glycosyl transferase family 2 4 166 1.9E-23 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 Astex_0514 0a6f84be98194262d47465d0497e4ec1 309 Gene3D G3DSA:3.90.550.10 1 216 1.0E-32 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_0514 0a6f84be98194262d47465d0497e4ec1 309 SUPERFAMILY SSF53448 1 216 7.78E-38 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_2888 c41472902e0c0ec298b0b9576eee5ba8 308 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 21 295 1.3E-50 T 13-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 Astex_0550 6e232dbeb4b49987b56100cbbd038cfd 78 TIGRFAM TIGR03510 XapX: XapX domain 8 53 2.0E-15 T 13-10-2018 IPR020017 XapX domain Astex_0243 3573ead0c5c9aa03517f374a24aa8bef 328 SUPERFAMILY SSF51735 1 310 7.37E-86 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily Astex_0243 3573ead0c5c9aa03517f374a24aa8bef 328 Gene3D G3DSA:3.90.25.10 183 306 5.2E-103 T 13-10-2018 Astex_0243 3573ead0c5c9aa03517f374a24aa8bef 328 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 302 2.6E-49 T 13-10-2018 IPR016040 NAD(P)-binding domain Astex_0243 3573ead0c5c9aa03517f374a24aa8bef 328 Gene3D G3DSA:3.40.50.720 3 293 5.2E-103 T 13-10-2018 Astex_0767 706ba80174e9f4868a802561d363a459 100 Pfam PF11342 Protein of unknown function (DUF3144) 9 84 2.5E-25 T 13-10-2018 IPR021490 Protein of unknown function DUF3144 Astex_3080 de2d1a5bfe4e6301e005857ac1c93cca 282 Gene3D G3DSA:3.40.50.1820 1 282 4.8E-79 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_3080 de2d1a5bfe4e6301e005857ac1c93cca 282 Pfam PF00756 Putative esterase 21 275 4.4E-53 T 13-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 Astex_3080 de2d1a5bfe4e6301e005857ac1c93cca 282 SUPERFAMILY SSF53474 2 281 9.02E-81 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_3080 de2d1a5bfe4e6301e005857ac1c93cca 282 TIGRFAM TIGR02821 fghA_ester_D: S-formylglutathione hydrolase 3 280 7.5E-113 T 13-10-2018 IPR014186 S-formylglutathione hydrolase GO:0018738|GO:0046294 KEGG: 00680+3.1.2.12|MetaCyc: PWY-1801|Reactome: R-HSA-156590 Astex_0030 4b07ab40a85cf93ee2a1776aeeaf205f 426 Pfam PF13657 HipA N-terminal domain 22 123 4.2E-17 T 13-10-2018 IPR017508 HipA, N-terminal subdomain 1 Astex_0030 4b07ab40a85cf93ee2a1776aeeaf205f 426 Pfam PF07804 HipA-like C-terminal domain 168 392 2.9E-42 T 13-10-2018 IPR012893 HipA-like, C-terminal Astex_1513 322b750fa000f67573bf8db6e41907fe 426 Pfam PF04932 O-Antigen ligase 202 339 1.4E-6 T 13-10-2018 IPR007016 O-antigen ligase-related Astex_3715 83d2e06984ee144517fe47a847bb6b0e 301 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 37 66 1.1E-5 T 13-10-2018 IPR006530 YD repeat Astex_3715 83d2e06984ee144517fe47a847bb6b0e 301 Pfam PF05593 RHS Repeat 37 69 7.7E-7 T 13-10-2018 IPR031325 RHS repeat Astex_1695 8f417ffa30fc70817893e1849e092630 378 Pfam PF07786 Protein of unknown function (DUF1624) 10 238 5.9E-10 T 13-10-2018 IPR012429 Domain of unknown function DUF1624 Reactome: R-HSA-2024096|Reactome: R-HSA-2206291|Reactome: R-HSA-6798695 Astex_3531 1c01825f657004155966398936c83048 434 Pfam PF03109 ABC1 family 109 221 5.2E-29 T 13-10-2018 IPR004147 UbiB domain Astex_3531 1c01825f657004155966398936c83048 434 SUPERFAMILY SSF56112 92 324 8.02E-14 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily Astex_1195 5b91bf66a768dd3811fc00ca264af136 336 Pfam PF10150 Ribonuclease E/G family 147 260 7.0E-18 T 13-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 Astex_0320 359620b3f1ddfc26121f74a6047df7dd 247 Pfam PF07750 GcrA cell cycle regulator 11 78 4.4E-10 T 13-10-2018 IPR011681 GcrA cell cycle regulator Astex_1868 11e84cc4888d2f97e8c5149f87298141 60 Gene3D G3DSA:3.30.160.160 2 48 4.4E-14 T 13-10-2018 Astex_1868 11e84cc4888d2f97e8c5149f87298141 60 Pfam PF07411 Domain of unknown function (DUF1508) 11 56 6.6E-16 T 13-10-2018 IPR010879 Domain of unknown function DUF1508 Astex_1868 11e84cc4888d2f97e8c5149f87298141 60 SUPERFAMILY SSF160113 1 56 1.96E-13 T 13-10-2018 IPR036913 YegP-like superfamily Astex_3131 fefde2983be57cfc81c7cab99204e1d0 139 Pfam PF05433 Glycine zipper 2TM domain 58 98 1.1E-10 T 13-10-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 Astex_0834 2f0b8d265677c6c68a4122cd7105651d 388 Pfam PF07394 Protein of unknown function (DUF1501) 96 364 2.4E-36 T 13-10-2018 IPR010869 Protein of unknown function DUF1501 Astex_1216 639c9e16a00006bce9024075616be4e1 473 Gene3D G3DSA:1.50.10.140 36 473 1.3E-150 T 13-10-2018 Astex_1216 639c9e16a00006bce9024075616be4e1 473 Pfam PF10091 Putative glucoamylase 213 457 1.6E-75 T 13-10-2018 IPR019282 Domain of unknown function DUF2329 Astex_1216 639c9e16a00006bce9024075616be4e1 473 PIRSF PIRSF028431 26 473 5.3E-149 T 13-10-2018 IPR016883 Uncharacterised conserved protein UCP028431 Astex_1546 d28c1712136bc4c456d30ed399a73f82 89 Pfam PF10073 Uncharacterized protein conserved in bacteria (DUF2312) 16 87 4.2E-34 T 13-10-2018 IPR018753 Azospirillum phage Cd, Gp10 Astex_1544 972daf94a9198d83868127b4e3620d02 417 Pfam PF01757 Acyltransferase family 24 383 7.5E-34 T 13-10-2018 IPR002656 Acyltransferase 3 GO:0016747 Astex_1782 08237e2b96de0548db85a3cba787622f 86 Pfam PF03693 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH 5 68 1.8E-4 T 13-10-2018 IPR022789 Antitoxin ParD Astex_1782 08237e2b96de0548db85a3cba787622f 86 TIGRFAM TIGR02606 antidote_CC2985: putative addiction module antidote protein, CC2985 family 5 69 2.4E-14 T 13-10-2018 IPR022789 Antitoxin ParD Astex_1782 08237e2b96de0548db85a3cba787622f 86 Gene3D G3DSA:1.10.8.1250 10 85 3.6E-10 T 13-10-2018 IPR038296 Antitoxin ParD superfamily Astex_1782 08237e2b96de0548db85a3cba787622f 86 SUPERFAMILY SSF47598 1 43 1.0E-8 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 Astex_3029 691592724e5ebdf19cc02848227d735b 379 Pfam PF03739 Predicted permease YjgP/YjgQ family 25 373 7.2E-48 T 13-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 Astex_2813 1cda6f7175c51a596c2515e1266de9bb 202 Gene3D G3DSA:1.20.120.1200 2 166 2.8E-44 T 13-10-2018 Astex_2813 1cda6f7175c51a596c2515e1266de9bb 202 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 17 164 3.0E-39 T 13-10-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_1157 b6a4b9a4cbf79c9bc02180442f8067e8 78 Pfam PF04380 Membrane fusogenic activity 2 62 4.7E-14 T 13-10-2018 IPR007475 Membrane fusogenic activity Astex_2207 942598da532ca71bd5d4cff71344e1de 302 Pfam PF00535 Glycosyl transferase family 2 5 132 7.0E-31 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 Astex_2207 942598da532ca71bd5d4cff71344e1de 302 SUPERFAMILY SSF53448 4 203 1.41E-47 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_2207 942598da532ca71bd5d4cff71344e1de 302 Gene3D G3DSA:3.90.550.10 2 239 7.8E-51 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_0406 af5475bef9dbd536b73b74af085766f4 231 Hamap MF_00766 Biosynthetic peptidoglycan transglycosylase [mtgA]. 9 223 39.39 T 13-10-2018 IPR011812 Biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Astex_0406 af5475bef9dbd536b73b74af085766f4 231 Gene3D G3DSA:1.10.3810.10 44 220 6.0E-50 T 13-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Astex_0406 af5475bef9dbd536b73b74af085766f4 231 TIGRFAM TIGR02070 mono_pep_trsgly: monofunctional biosynthetic peptidoglycan transglycosylase 13 221 1.7E-82 T 13-10-2018 IPR011812 Biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Astex_0406 af5475bef9dbd536b73b74af085766f4 231 Pfam PF00912 Transglycosylase 51 209 1.2E-49 T 13-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Astex_0406 af5475bef9dbd536b73b74af085766f4 231 SUPERFAMILY SSF53955 51 213 7.87E-56 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily Astex_3653 104ebe8cdb7d8242101c363e5f2a516f 175 Gene3D G3DSA:3.40.630.30 5 164 4.0E-37 T 13-10-2018 Astex_3653 104ebe8cdb7d8242101c363e5f2a516f 175 SUPERFAMILY SSF55729 26 153 3.4E-7 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Astex_3127 d95504ef8746606cc90b099682189eb4 280 SMART SM00986 123 273 4.4E-9 T 13-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Astex_3127 d95504ef8746606cc90b099682189eb4 280 Gene3D G3DSA:3.40.470.10 82 279 1.0E-31 T 13-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Astex_3127 d95504ef8746606cc90b099682189eb4 280 SMART SM00987 123 273 4.4E-9 T 13-10-2018 Astex_3127 d95504ef8746606cc90b099682189eb4 280 SUPERFAMILY SSF52141 99 276 2.68E-29 T 13-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Astex_3127 d95504ef8746606cc90b099682189eb4 280 Pfam PF03167 Uracil DNA glycosylase superfamily 125 272 2.5E-20 T 13-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 Astex_1365 90febed1bccde99f22470e20b4e12565 321 Pfam PF05982 Na+-dependent bicarbonate transporter superfamily 16 316 5.0E-104 T 13-10-2018 IPR010293 Na+-dependent bicarbonate transporter superfamily Astex_2684 dff3061f3e8df174a150e35a98c20eec 634 Gene3D G3DSA:2.115.10.20 332 613 3.4E-83 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Astex_2684 dff3061f3e8df174a150e35a98c20eec 634 Pfam PF04616 Glycosyl hydrolases family 43 75 219 8.8E-7 T 13-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 Astex_2684 dff3061f3e8df174a150e35a98c20eec 634 Pfam PF04616 Glycosyl hydrolases family 43 336 605 2.7E-57 T 13-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 Astex_2684 dff3061f3e8df174a150e35a98c20eec 634 SUPERFAMILY SSF75005 71 309 3.28E-22 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Astex_2684 dff3061f3e8df174a150e35a98c20eec 634 Gene3D G3DSA:2.115.10.20 72 302 1.0E-18 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Astex_2684 dff3061f3e8df174a150e35a98c20eec 634 SUPERFAMILY SSF75005 336 613 2.49E-66 T 13-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Astex_0727 463b0a7b13099922065a8af95ccf034c 273 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 4 232 3.4E-19 T 13-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 Astex_0795 8decfd66daf982b3e4b85c8bbfbf6597 202 Pfam PF13761 Domain of unknown function (DUF4166) 16 193 5.1E-40 T 13-10-2018 IPR025311 Domain of unknown function DUF4166 Astex_1814 41e4c009edfdaa893526299a00c1a098 178 Pfam PF02517 CAAX protease self-immunity 61 158 2.8E-12 T 13-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 Astex_3548 4021215991da97438d83a90d1cfc7106 418 PIRSF PIRSF014753 23 415 4.4E-100 T 13-10-2018 IPR016624 Uncharacterised conserved protein UCP014753 Astex_3548 4021215991da97438d83a90d1cfc7106 418 Pfam PF10022 Uncharacterized protein conserved in bacteria (DUF2264) 35 399 2.2E-111 T 13-10-2018 IPR016624 Uncharacterised conserved protein UCP014753 Astex_2741 b955e19e874d20fa802633f321f64f71 280 Gene3D G3DSA:2.160.20.120 203 277 5.3E-10 T 13-10-2018 Astex_2741 b955e19e874d20fa802633f321f64f71 280 Gene3D G3DSA:2.160.20.120 19 202 2.7E-10 T 13-10-2018 Astex_0780 9cfb66976e7d7f413c5462ae23f87148 222 Pfam PF06347 Bacterial SH3 domain 151 199 5.4E-6 T 13-10-2018 IPR010466 Protein of unknown function DUF1058 Astex_0780 9cfb66976e7d7f413c5462ae23f87148 222 Pfam PF06347 Bacterial SH3 domain 82 135 1.9E-10 T 13-10-2018 IPR010466 Protein of unknown function DUF1058 Astex_0780 9cfb66976e7d7f413c5462ae23f87148 222 Gene3D G3DSA:2.30.30.40 73 139 1.1E-5 T 13-10-2018 Astex_3111 0ed013461ba35f41849ceee52f6e4299 141 Pfam PF07378 Flagellar protein FlbT 3 127 2.3E-46 T 13-10-2018 IPR009967 Flagellum biosynthesis repressor FlbT GO:0006402|GO:0048027|GO:1902209 Astex_3111 0ed013461ba35f41849ceee52f6e4299 141 PIRSF PIRSF009533 1 141 3.0E-50 T 13-10-2018 IPR009967 Flagellum biosynthesis repressor FlbT GO:0006402|GO:0048027|GO:1902209 Astex_3161 6de4bad9378c86a82eb690226d1e9eac 502 Pfam PF02706 Chain length determinant protein 32 124 8.9E-8 T 13-10-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 Astex_2264 acf34739825d17f0dc6a2b2678c04547 443 Gene3D G3DSA:3.90.550.10 162 406 4.7E-43 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_2264 acf34739825d17f0dc6a2b2678c04547 443 Pfam PF13641 Glycosyltransferase like family 2 172 392 9.0E-15 T 13-10-2018 Astex_2264 acf34739825d17f0dc6a2b2678c04547 443 SUPERFAMILY SSF53448 171 406 5.91E-44 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_3088 4496755c1f0b7a2be20cdce1e8d44af4 265 Pfam PF01904 Protein of unknown function DUF72 20 262 2.3E-54 T 13-10-2018 IPR002763 Protein of unknown function DUF72 Astex_3088 4496755c1f0b7a2be20cdce1e8d44af4 265 SUPERFAMILY SSF117396 1 264 5.23E-67 T 13-10-2018 IPR036520 UPF0759 superfamily Astex_3088 4496755c1f0b7a2be20cdce1e8d44af4 265 Gene3D G3DSA:3.20.20.410 1 262 1.8E-51 T 13-10-2018 IPR036520 UPF0759 superfamily Astex_3495 8566f34a553c0a16762ec72a53f63f59 321 Pfam PF04344 Chemotaxis phosphatase, CheZ 125 201 2.4E-8 T 13-10-2018 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 Astex_3495 8566f34a553c0a16762ec72a53f63f59 321 SUPERFAMILY SSF75708 43 212 2.75E-35 T 13-10-2018 Astex_3495 8566f34a553c0a16762ec72a53f63f59 321 Gene3D G3DSA:1.10.287.500 115 167 4.7E-7 T 13-10-2018 Astex_2468 988edc11be406fdde1e0aa90338f8bc0 428 SUPERFAMILY SSF103473 10 416 2.22E-53 T 13-10-2018 IPR036259 MFS transporter superfamily Astex_2468 988edc11be406fdde1e0aa90338f8bc0 428 Gene3D G3DSA:1.20.1250.20 2 414 1.0E-54 T 13-10-2018 Astex_2468 988edc11be406fdde1e0aa90338f8bc0 428 Pfam PF07690 Major Facilitator Superfamily 24 374 1.8E-44 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Astex_2649 c8b063451f691f66654b369d2a755760 112 Pfam PF07509 Protein of unknown function (DUF1523) 48 111 2.4E-6 T 13-10-2018 IPR011088 Bacteriophage phiNM3, A0EWY4 Astex_3160 21eff504ed42829fcc5ba26ef0b21da0 238 SUPERFAMILY SSF52540 27 230 6.11E-9 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_3160 21eff504ed42829fcc5ba26ef0b21da0 238 Gene3D G3DSA:3.40.50.300 3 233 4.0E-14 T 13-10-2018 Astex_3440 6d1d8cf2783aa3951a293ace781e0960 51 Pfam PF05545 Cbb3-type cytochrome oxidase component FixQ 11 46 2.5E-10 T 13-10-2018 IPR008621 Cbb3-type cytochrome oxidase component Astex_3066 36fbdabeb8ae6d0c8e1c0f91e887cafa 107 Gene3D G3DSA:1.10.790.20 1 107 2.2E-38 T 13-10-2018 Astex_3066 36fbdabeb8ae6d0c8e1c0f91e887cafa 107 PIRSF PIRSF031780 1 107 1.8E-38 T 13-10-2018 IPR009945 Protein of unknown function DUF1476 Astex_3066 36fbdabeb8ae6d0c8e1c0f91e887cafa 107 Pfam PF07345 Domain of unknown function (DUF1476) 1 101 3.6E-40 T 13-10-2018 IPR009945 Protein of unknown function DUF1476 Astex_2038 ad9e5d8fa36454d644d3acb1504e71ab 366 SUPERFAMILY SSF55729 182 339 1.25E-7 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Astex_3773 8fddbe87d0e7708cbd996c967b636e4e 685 SUPERFAMILY SSF109709 106 198 6.67E-7 T 13-10-2018 Astex_2893 bac13f53a77701abbb5e92e2a41af966 101 Gene3D G3DSA:3.30.160.190 1 79 1.2E-31 T 13-10-2018 IPR038532 NADH dehydrogenase ubiquinone Fe-S protein 4-like superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2893 bac13f53a77701abbb5e92e2a41af966 101 Pfam PF04800 ETC complex I subunit conserved region 3 96 1.2E-34 T 13-10-2018 IPR006885 NADH dehydrogenase ubiquinone Fe-S protein 4, mitochondrial GO:0016651|GO:0022900 Astex_3805 d888520ab00d733aa28ac382c5d6ec35 146 Gene3D G3DSA:1.10.10.1550 54 110 1.1E-30 T 13-10-2018 Astex_3805 d888520ab00d733aa28ac382c5d6ec35 146 Pfam PF05443 ROS/MUCR transcriptional regulator protein 8 127 4.7E-49 T 13-10-2018 IPR008807 ROSMUCR transcriptional regulator GO:0003677|GO:0006355|GO:0008270 Astex_3859 e72f38a10150d4dc09712ad1e2317746 436 Gene3D G3DSA:1.20.1600.10 26 426 5.8E-39 T 13-10-2018 Astex_3859 e72f38a10150d4dc09712ad1e2317746 436 Pfam PF02321 Outer membrane efflux protein 257 416 9.5E-14 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 Astex_3859 e72f38a10150d4dc09712ad1e2317746 436 SUPERFAMILY SSF56954 19 425 3.01E-51 T 13-10-2018 Astex_2896 d16c6cda783a9eed1aa64695b5028883 180 Pfam PF03840 Preprotein translocase SecG subunit 5 70 6.9E-17 T 13-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 Astex_2896 d16c6cda783a9eed1aa64695b5028883 180 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 4 71 5.3E-18 T 13-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 Astex_2896 d16c6cda783a9eed1aa64695b5028883 180 PRINTS PR01651 Protein-export SecG membrane protein signature 52 74 7.9E-10 T 13-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 Astex_2896 d16c6cda783a9eed1aa64695b5028883 180 PRINTS PR01651 Protein-export SecG membrane protein signature 4 24 7.9E-10 T 13-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 Astex_3767 a459914d0a19ad5ecfb34bf83671154e 412 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 49 355 1.5E-40 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 Astex_3767 a459914d0a19ad5ecfb34bf83671154e 412 SUPERFAMILY SSF52540 37 378 2.24E-12 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase Astex_0233 1cb5c96ddd9c677692826e35dc249f48 186 Pfam PF10067 Predicted membrane protein (DUF2306) 71 163 1.1E-7 T 13-10-2018 IPR018750 Protein of unknown function DUF2306, membrane Astex_0078 6baf6ca92ae1b493901ea5c863d017e5 280 SUPERFAMILY SSF69593 64 210 7.98E-14 T 13-10-2018 Astex_0078 6baf6ca92ae1b493901ea5c863d017e5 280 Pfam PF01553 Acyltransferase 74 203 2.5E-11 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 Astex_0078 6baf6ca92ae1b493901ea5c863d017e5 280 SMART SM00563 84 207 1.9E-4 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 Astex_0345 bfc4871bfc139a4e5280355edb6821f9 984 SUPERFAMILY SSF49265 555 610 4.03E-7 T 13-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 Astex_0345 bfc4871bfc139a4e5280355edb6821f9 984 Gene3D G3DSA:2.60.40.10 545 617 2.6E-7 T 13-10-2018 IPR013783 Immunoglobulin-like fold Astex_1537 2d1d7511b4affd7d9cfd5c5b2acc8ac7 238 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 161 221 2.4E-5 T 13-10-2018 IPR037682 TonB, C-terminal GO:0055085 Astex_2482 3454c1076661b1441cf4f2a5c9d87d85 119 Pfam PF04956 TrbC/VIRB2 family 20 109 3.5E-24 T 13-10-2018 IPR007039 Conjugal transfer TrbC/type IV secretion VirB2 Astex_0898 d7515a121837dbb737e126621a68cd91 65 Pfam PF13617 YnbE-like lipoprotein 13 63 3.0E-14 T 13-10-2018 IPR025985 YnbE-like lipoprotein Astex_1044 d1f8e6008182fa8a7792a4262d886a50 288 TIGRFAM TIGR04052 AZL_007920_fam: AZL_007920/MXAN_0976 family protein 65 273 5.8E-66 T 13-10-2018 IPR023977 Conserved hypotheical protein CHP04052 Astex_2583 d10c95e6bfbc84fca9ab1805aa0d285b 604 SUPERFAMILY SSF51161 462 564 3.4E-9 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily Astex_0010 5414045ba16e7db75f708ab3b4a82ebc 139 SUPERFAMILY SSF46785 4 138 1.0E-23 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily Astex_0010 5414045ba16e7db75f708ab3b4a82ebc 139 Pfam PF02082 Transcriptional regulator 1 86 5.2E-19 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type Astex_0010 5414045ba16e7db75f708ab3b4a82ebc 139 Gene3D G3DSA:1.10.10.10 1 139 4.1E-37 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily Astex_1548 b8e27376ccafc9876fb738af41ddca35 195 Pfam PF12915 Protein of unknown function (DUF3833) 20 179 5.0E-56 T 13-10-2018 IPR024409 Protein of unknown function DUF3833 Astex_0627 bee9bff268eec328af4dd6c479576868 109 Gene3D G3DSA:3.40.1530.20 1 108 1.8E-34 T 13-10-2018 Astex_0627 bee9bff268eec328af4dd6c479576868 109 Pfam PF07372 Protein of unknown function (DUF1491) 3 102 2.9E-32 T 13-10-2018 IPR009964 Protein of unknown function DUF1491 Astex_2279 2d609e030576ebe3dc01028bbe819e1b 390 Pfam PF04577 Protein of unknown function (DUF563) 163 367 5.2E-40 T 13-10-2018 IPR007657 Glycosyltransferase 61 GO:0016757 Astex_2208 5b38985c65317f0968fbc71e2de40dc4 159 Gene3D G3DSA:3.40.50.2000 1 156 3.0E-19 T 13-10-2018 Astex_2208 5b38985c65317f0968fbc71e2de40dc4 159 SUPERFAMILY SSF53756 2 91 8.9E-7 T 13-10-2018 Astex_2208 5b38985c65317f0968fbc71e2de40dc4 159 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 1 109 1.4E-9 T 13-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 Astex_3163 39186de0a0115324912c3f1a89f76f18 90 Gene3D G3DSA:1.25.40.10 14 89 1.1E-11 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_0266 31563e55c4f8973237040ddf95405968 96 Gene3D G3DSA:3.30.70.100 1 96 3.7E-34 T 13-10-2018 Astex_0266 31563e55c4f8973237040ddf95405968 96 SUPERFAMILY SSF54909 1 95 7.38E-32 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel Astex_0266 31563e55c4f8973237040ddf95405968 96 Pfam PF07045 Domain of unknown function (DUF1330) 3 95 2.2E-32 T 13-10-2018 IPR010753 Domain of unknown function DUF1330 Astex_2117 a71ea763c92953fd16033e3de4e3d84b 280 SUPERFAMILY SSF56529 3 263 2.59E-34 T 13-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 Astex_2117 a71ea763c92953fd16033e3de4e3d84b 280 Gene3D G3DSA:3.90.850.10 1 265 9.8E-53 T 13-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 Astex_2912 10f6ec792b9772beda4150f2609a4f34 308 Pfam PF12146 Serine aminopeptidase, S33 100 203 5.2E-7 T 13-10-2018 IPR022742 Serine aminopeptidase, S33 Astex_2912 10f6ec792b9772beda4150f2609a4f34 308 Gene3D G3DSA:3.40.50.1820 72 269 5.2E-8 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_2912 10f6ec792b9772beda4150f2609a4f34 308 SUPERFAMILY SSF53474 90 244 5.27E-8 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_2565 ed86116131eea787352fac77eca74bb4 104 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 6 95 3.5E-9 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family Astex_2565 ed86116131eea787352fac77eca74bb4 104 Gene3D G3DSA:3.30.2310.20 1 99 4.8E-15 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Astex_3732 8125d766b51cf66de0bbfe5d6c00e8a5 185 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 65 86 0.0028 T 13-10-2018 IPR006530 YD repeat Astex_3732 8125d766b51cf66de0bbfe5d6c00e8a5 185 Pfam PF05593 RHS Repeat 53 89 1.1E-9 T 13-10-2018 IPR031325 RHS repeat Astex_1554 c25acb80e2ce2e7d36ddd6cb82c205dc 279 Pfam PF05675 Protein of unknown function (DUF817) 21 256 2.7E-100 T 13-10-2018 IPR008535 Protein of unknown function DUF817 Astex_1554 c25acb80e2ce2e7d36ddd6cb82c205dc 279 PIRSF PIRSF009141 11 276 1.2E-92 T 13-10-2018 IPR008535 Protein of unknown function DUF817 Astex_2490 69045e284f18563223e49bdc6d820901 70 Pfam PF10038 Protein of unknown function (DUF2274) 1 67 7.1E-28 T 13-10-2018 IPR018733 Protein of unknown function DUF2274 Astex_3234 9a36463cc19e74069e25ab4d0ea23f11 526 Pfam PF03050 Transposase IS66 family 185 469 4.4E-104 T 13-10-2018 IPR004291 Transposase, IS66 Astex_3234 9a36463cc19e74069e25ab4d0ea23f11 526 Pfam PF13817 IS66 C-terminal element 476 513 5.5E-15 T 13-10-2018 IPR039552 Transposase IS66, C-terminal Astex_3234 9a36463cc19e74069e25ab4d0ea23f11 526 Pfam PF13007 Transposase C of IS166 homeodomain 47 119 3.1E-14 T 13-10-2018 IPR024463 Transposase TnpC, homeodomain Astex_3234 9a36463cc19e74069e25ab4d0ea23f11 526 Pfam PF13005 zinc-finger binding domain of transposase IS66 125 170 1.5E-8 T 13-10-2018 IPR024474 Zinc-finger binding domain of transposase IS66 Astex_3815 b61874cf719d3d0d899a3618a02de347 432 Pfam PF03235 Protein of unknown function DUF262 25 87 3.0E-14 T 13-10-2018 IPR004919 Domain of unknown function DUF262 Astex_1113 204328b567d20cdac78dd215174892e9 168 Pfam PF00430 ATP synthase B/B' CF(0) 24 143 1.7E-17 T 13-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 Astex_1113 204328b567d20cdac78dd215174892e9 168 Hamap MF_01398 ATP synthase subunit b [atpF]. 4 145 10.347 T 13-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 Astex_0897 c63e4827cb3115e498f9c8ae1861b5c1 1182 Pfam PF11739 Dicarboxylate transport 1054 1165 1.4E-7 T 13-10-2018 IPR021730 Dicarboxylate transport Astex_0897 c63e4827cb3115e498f9c8ae1861b5c1 1182 Pfam PF11739 Dicarboxylate transport 931 1055 3.3E-12 T 13-10-2018 IPR021730 Dicarboxylate transport Astex_3507 60715b910eb5cf2d6e848d20bb80e7f2 547 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 15 519 26.405 T 13-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 Astex_3507 60715b910eb5cf2d6e848d20bb80e7f2 547 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 19 354 1.7E-117 T 13-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 Astex_3507 60715b910eb5cf2d6e848d20bb80e7f2 547 Pfam PF13742 OB-fold nucleic acid binding domain 18 110 5.7E-25 T 13-10-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 Astex_3507 60715b910eb5cf2d6e848d20bb80e7f2 547 Pfam PF02601 Exonuclease VII, large subunit 134 377 1.1E-80 T 13-10-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 Astex_3507 60715b910eb5cf2d6e848d20bb80e7f2 547 Pfam PF02601 Exonuclease VII, large subunit 367 511 4.3E-12 T 13-10-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 Astex_3850 f22cc00136ea936eed7323488149d7e7 165 Pfam PF03713 Domain of unknown function (DUF305) 112 159 1.4E-10 T 13-10-2018 IPR005183 Domain of unknown function DUF305 Astex_3850 f22cc00136ea936eed7323488149d7e7 165 Gene3D G3DSA:1.20.1260.10 101 164 1.5E-10 T 13-10-2018 IPR012347 Ferritin-like Astex_3283 a1a2f8661173a14a416acd0a40c429e4 125 Pfam PF00034 Cytochrome c 29 124 6.2E-11 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_3283 a1a2f8661173a14a416acd0a40c429e4 125 Gene3D G3DSA:1.10.760.10 19 124 5.1E-35 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Astex_3283 a1a2f8661173a14a416acd0a40c429e4 125 SUPERFAMILY SSF46626 26 124 1.67E-27 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 Astex_3283 a1a2f8661173a14a416acd0a40c429e4 125 PRINTS PR00604 Class IA and IB cytochrome C signature 50 65 5.3E-13 T 13-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_3283 a1a2f8661173a14a416acd0a40c429e4 125 PRINTS PR00604 Class IA and IB cytochrome C signature 38 45 5.3E-13 T 13-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_3283 a1a2f8661173a14a416acd0a40c429e4 125 PRINTS PR00604 Class IA and IB cytochrome C signature 99 109 5.3E-13 T 13-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_3283 a1a2f8661173a14a416acd0a40c429e4 125 PRINTS PR00604 Class IA and IB cytochrome C signature 116 124 5.3E-13 T 13-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_3283 a1a2f8661173a14a416acd0a40c429e4 125 PRINTS PR00604 Class IA and IB cytochrome C signature 80 96 5.3E-13 T 13-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_1591 d24ba0119b2628a273a92cdf8d2b686a 529 Pfam PF16192 C-terminal four TMM region of protein-O-mannosyltransferase 339 509 1.5E-17 T 13-10-2018 IPR032421 Protein O-mannosyl-transferase, C-terminal four TM domain KEGG: 00514+2.4.1.109|KEGG: 00515+2.4.1.109|MetaCyc: PWY-7921|MetaCyc: PWY-7922|MetaCyc: PWY-7979|Reactome: R-HSA-5173105 Astex_1591 d24ba0119b2628a273a92cdf8d2b686a 529 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 46 281 1.9E-17 T 13-10-2018 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 Reactome: R-HSA-5173105 Astex_0455 f41735498365b5573fbf8e2572093af9 143 Pfam PF08906 Domain of unknown function (DUF1851) 62 111 5.6E-7 T 13-10-2018 IPR015002 Domain of unknown function DUF1851 Astex_0427 9ee2c5fec425952da948598914d8b845 57 Pfam PF04964 Flp/Fap pilin component 8 52 1.5E-18 T 13-10-2018 IPR007047 Flp/Fap pilin component Astex_1765 05d0d440d344189b476801705fb0bac2 145 Gene3D G3DSA:3.30.420.270 68 139 5.8E-15 T 13-10-2018 Astex_1765 05d0d440d344189b476801705fb0bac2 145 Pfam PF02472 Biopolymer transport protein ExbD/TolR 16 142 2.3E-25 T 13-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 Astex_3486 08e3c366cb469dd3087ca04e5673adeb 263 Pfam PF07386 Protein of unknown function (DUF1499) 123 261 2.5E-17 T 13-10-2018 IPR010865 Protein of unknown function DUF1499 Astex_1103 26a706ba0e4c3f52b51b781a7c6471fe 327 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 13 321 2.8E-120 T 13-10-2018 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 Astex_1103 26a706ba0e4c3f52b51b781a7c6471fe 327 Pfam PF03741 Integral membrane protein TerC family 78 286 1.8E-50 T 13-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 Astex_3589 d1b86148b389f145b932f28ed74eb143 236 Pfam PF02104 SURF1 family 12 216 7.7E-39 T 13-10-2018 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 Astex_3357 4d400b4c7bba8caa965d6a08da035d5d 132 SUPERFAMILY SSF140804 19 108 2.62E-21 T 13-10-2018 IPR027405 YidB-like Astex_3357 4d400b4c7bba8caa965d6a08da035d5d 132 Gene3D G3DSA:1.10.10.690 1 132 1.3E-25 T 13-10-2018 IPR027405 YidB-like Astex_3041 4c369e1ced68119289cab18235c19b58 255 Pfam PF03883 Peroxide stress protein YaaA 1 239 2.8E-80 T 13-10-2018 IPR005583 Peroxide stress protein YaaA Astex_3041 4c369e1ced68119289cab18235c19b58 255 Hamap MF_00652 UPF0246 protein YaaA [yaaA]. 1 251 31.408 T 13-10-2018 IPR005583 Peroxide stress protein YaaA Astex_0702 f992fdf53c5c578a7e35ffe48acf7fff 234 Pfam PF07277 SapC 7 222 3.3E-61 T 13-10-2018 IPR010836 SapC Astex_1129 5196d7bc50822f9915ff3b67c5b942d6 189 Pfam PF05656 Protein of unknown function (DUF805) 14 176 1.5E-27 T 13-10-2018 IPR008523 Protein of unknown function DUF805 GO:0016021 Astex_2244 7e07fe158dfaf8479beebe23c9b77d56 99 Pfam PF04956 TrbC/VIRB2 family 13 97 5.7E-16 T 13-10-2018 IPR007039 Conjugal transfer TrbC/type IV secretion VirB2 Astex_1956 329e7d29ac37887b0bd9423ac710441c 127 Gene3D G3DSA:1.10.490.10 3 123 3.0E-36 T 13-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 Astex_1956 329e7d29ac37887b0bd9423ac710441c 127 SUPERFAMILY SSF46458 9 116 1.38E-23 T 13-10-2018 IPR009050 Globin-like superfamily Astex_1956 329e7d29ac37887b0bd9423ac710441c 127 Pfam PF01152 Bacterial-like globin 9 96 5.9E-7 T 13-10-2018 IPR001486 Truncated hemoglobin GO:0019825 Astex_0928 ee043bc64fd43c725d16ec4d8b44ee4a 153 Pfam PF02391 MoaE protein 20 121 1.1E-29 T 13-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 Astex_0928 ee043bc64fd43c725d16ec4d8b44ee4a 153 SUPERFAMILY SSF54690 21 151 1.29E-39 T 13-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 Astex_0928 ee043bc64fd43c725d16ec4d8b44ee4a 153 Gene3D G3DSA:3.90.1170.40 4 151 2.7E-39 T 13-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 Astex_3700 a3db42b19904f15bd638f31ae4a056bd 277 Pfam PF05114 Protein of unknown function (DUF692) 10 271 4.8E-106 T 13-10-2018 IPR007801 Uncharacterised protein family UPF0276 Astex_3700 a3db42b19904f15bd638f31ae4a056bd 277 Gene3D G3DSA:3.20.20.150 8 276 1.4E-95 T 13-10-2018 Astex_3700 a3db42b19904f15bd638f31ae4a056bd 277 SUPERFAMILY SSF51658 62 250 7.33E-5 T 13-10-2018 IPR036237 Xylose isomerase-like superfamily Astex_0670 cd4cb25f1d2075a0b849fc75bc69c13a 376 Gene3D G3DSA:1.10.10.2520 161 250 3.3E-24 T 13-10-2018 Astex_0670 cd4cb25f1d2075a0b849fc75bc69c13a 376 Pfam PF07486 Cell Wall Hydrolase 177 286 1.0E-26 T 13-10-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 Astex_0639 b635f2a73377b6f952eb4f59a5744379 181 Gene3D G3DSA:3.90.550.10 1 180 5.0E-31 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_0639 b635f2a73377b6f952eb4f59a5744379 181 Pfam PF12804 MobA-like NTP transferase domain 5 135 2.6E-20 T 13-10-2018 IPR025877 MobA-like NTP transferase Astex_0639 b635f2a73377b6f952eb4f59a5744379 181 SUPERFAMILY SSF53448 1 173 6.76E-21 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases Astex_3227 53b6d2dee503b270aab2920e0fd156fc 131 Pfam PF05656 Protein of unknown function (DUF805) 14 119 1.1E-33 T 13-10-2018 IPR008523 Protein of unknown function DUF805 GO:0016021 Astex_3703 48c6a2077f5afdab3f9c5f3795690321 222 Pfam PF06532 Protein of unknown function (DUF1109) 13 222 1.3E-37 T 13-10-2018 IPR009495 Anti-sigma-F factor NrsF Astex_3541 460ce8bd0952440a262fd41a8752a302 224 Pfam PF10677 Protein of unknown function (DUF2490) 29 210 6.3E-44 T 13-10-2018 IPR019619 Protein of unknown function DUF2490 Astex_1429 deeda49846949755235fd93205e3020b 293 Pfam PF01145 SPFH domain / Band 7 family 39 236 4.0E-21 T 13-10-2018 IPR001107 Band 7 domain Astex_2186 cbe0d4f328264050c501170c90bd3c94 188 Pfam PF10531 SLBB domain 115 159 2.0E-6 T 13-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 Astex_2186 cbe0d4f328264050c501170c90bd3c94 188 Gene3D G3DSA:3.10.560.10 100 185 4.1E-13 T 13-10-2018 Astex_2186 cbe0d4f328264050c501170c90bd3c94 188 Pfam PF02563 Polysaccharide biosynthesis/export protein 35 109 5.2E-20 T 13-10-2018 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 Astex_3036 92eb73eaeaf6138b9edb5a1a30e2a692 160 Gene3D G3DSA:2.40.50.140 95 159 8.5E-9 T 13-10-2018 Astex_3036 92eb73eaeaf6138b9edb5a1a30e2a692 160 Pfam PF01957 NfeD-like C-terminal, partner-binding 17 159 1.1E-15 T 13-10-2018 IPR002810 NfeD-like, C-terminal domain Astex_1199 759b2c987bda07e3fcbb3f9e71163149 317 Pfam PF01963 TraB family 49 313 3.5E-24 T 13-10-2018 IPR002816 Pheromone shutdown, TraB Astex_1818 ab18c48b0f9009a0956832f491eb3337 230 Gene3D G3DSA:3.10.310.50 106 228 4.9E-29 T 13-10-2018 Astex_3122 4fc08889259325d3747c32cf8d1182f8 431 Gene3D G3DSA:1.20.1250.20 9 208 6.3E-8 T 13-10-2018 Astex_3122 4fc08889259325d3747c32cf8d1182f8 431 SUPERFAMILY SSF103473 16 424 8.24E-21 T 13-10-2018 IPR036259 MFS transporter superfamily Astex_3829 de3a15ec3f078ce2cbb758618075bc2f 401 Pfam PF05275 Copper resistance protein B precursor (CopB) 195 401 2.9E-74 T 13-10-2018 IPR007939 Copper resistance B precursor GO:0005507|GO:0006878|GO:0009279 Astex_1703 c24092d9785510b78e42665fd1885dd0 142 Pfam PF04325 Protein of unknown function (DUF465) 87 133 5.2E-14 T 13-10-2018 IPR007420 Protein of unknown function DUF465 Astex_1795 c738a9130f243056d40273283a77beed 118 Pfam PF16133 Domain of unknown function (DUF4844) 9 117 7.8E-22 T 13-10-2018 IPR032301 Protein of unknown function DUF4844 Astex_1795 c738a9130f243056d40273283a77beed 118 Gene3D G3DSA:1.20.1480.40 2 118 6.9E-23 T 13-10-2018 Astex_3696 7542d8806799817b8fead4e958411aa3 251 Pfam PF09836 Putative DNA-binding domain 4 91 8.7E-19 T 13-10-2018 IPR018640 Putative DNA-binding domain, bacteria Astex_0846 a93102614ef84d62847562c8a7a633b7 169 SUPERFAMILY SSF53254 1 149 6.42E-19 T 13-10-2018 IPR029033 Histidine phosphatase superfamily Astex_0846 a93102614ef84d62847562c8a7a633b7 169 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 88 2.8E-8 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 Astex_0846 a93102614ef84d62847562c8a7a633b7 169 Gene3D G3DSA:3.40.50.1240 1 155 1.5E-32 T 13-10-2018 IPR029033 Histidine phosphatase superfamily Astex_3681 117a48978efbe7d2dab20a6800963cc5 235 Pfam PF06693 Protein of unknown function (DUF1190) 57 232 4.6E-24 T 13-10-2018 IPR009576 Biofilm formation YgiB Astex_0020 ab815959a3018edd779726a7cc993b0d 264 SUPERFAMILY SSF53474 26 221 1.46E-20 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_0020 ab815959a3018edd779726a7cc993b0d 264 Gene3D G3DSA:3.40.50.1820 16 251 7.7E-22 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1999 2293931439a6a90ac918b97c0ceb6acf 51 Pfam PF08085 Entericidin EcnA/B family 26 46 1.1E-10 T 13-10-2018 IPR012556 Entericidin A/B GO:0009636|GO:0016020 Astex_0906 260256d89fda208ade462ef9f0ea08ab 399 Pfam PF00872 Transposase, Mutator family 4 371 3.8E-125 T 13-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 Astex_0544 260256d89fda208ade462ef9f0ea08ab 399 Pfam PF00872 Transposase, Mutator family 4 371 3.8E-125 T 13-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 Astex_0021 87134a1d5c62560517d99694604a27e8 248 Gene3D G3DSA:3.40.50.1820 13 246 4.5E-21 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_0021 87134a1d5c62560517d99694604a27e8 248 SUPERFAMILY SSF53474 14 244 1.67E-18 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1700 022ea03c953dd9e202e4409e4340838d 274 Pfam PF13672 Protein phosphatase 2C 10 230 2.0E-7 T 13-10-2018 Astex_1700 022ea03c953dd9e202e4409e4340838d 274 SUPERFAMILY SSF81606 11 220 1.96E-7 T 13-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 Astex_1221 134643be9dfab7b7120ad33339481d95 316 Gene3D G3DSA:3.40.50.10610 130 285 6.6E-17 T 13-10-2018 Astex_1221 134643be9dfab7b7120ad33339481d95 316 Pfam PF03783 Curli production assembly/transport component CsgG 141 260 1.0E-9 T 13-10-2018 IPR005534 Curli production assembly/transport component CsgG GO:0030288 Astex_0347 dd0dd6b79fc5d435870e6764e3d7c942 404 SUPERFAMILY SSF52266 209 394 5.83E-8 T 13-10-2018 Astex_0347 dd0dd6b79fc5d435870e6764e3d7c942 404 Gene3D G3DSA:3.40.50.1110 200 396 5.0E-7 T 13-10-2018 IPR036514 SGNH hydrolase superfamily Astex_1540 1927faa57274a4ca369814e4ddcde633 291 Pfam PF01618 MotA/TolQ/ExbB proton channel family 169 268 5.7E-31 T 13-10-2018 IPR002898 MotA/TolQ/ExbB proton channel Astex_1162 3519ed3046d8e3e386fb6d623c1eb588 291 Pfam PF14257 Domain of unknown function (DUF4349) 28 276 1.5E-41 T 13-10-2018 IPR025645 Domain of unknown function DUF4349 Astex_1175 0ecdfbb00e0d77facfcf3eb1d274ddb4 160 Pfam PF05656 Protein of unknown function (DUF805) 54 139 1.2E-18 T 13-10-2018 IPR008523 Protein of unknown function DUF805 GO:0016021 Astex_3598 cd0d9a807d542b6c86f8856e6acb4cbc 757 SUPERFAMILY SSF48208 312 744 2.15E-38 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 Astex_3695 7a8d43f8747d7b10b7331689c05e648a 146 Pfam PF07681 DoxX 25 112 4.1E-15 T 13-10-2018 IPR032808 DoxX family Astex_1997 a42a8b4878ce5f25c169dfafc87e6930 154 SUPERFAMILY SSF52172 10 139 8.97E-27 T 13-10-2018 IPR011006 CheY-like superfamily Astex_1997 a42a8b4878ce5f25c169dfafc87e6930 154 Pfam PF00072 Response regulator receiver domain 13 136 2.4E-18 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1997 a42a8b4878ce5f25c169dfafc87e6930 154 SMART SM00448 10 136 1.1E-20 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Astex_1997 a42a8b4878ce5f25c169dfafc87e6930 154 Gene3D G3DSA:3.40.50.2300 4 149 1.4E-30 T 13-10-2018 Astex_0116 5460f040d91acaaf5e358e78ab6eb59e 157 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 6 149 3.0E-32 T 13-10-2018 IPR002178 PTS EIIA type-2 domain Astex_0116 5460f040d91acaaf5e358e78ab6eb59e 157 Gene3D G3DSA:3.40.930.10 1 156 4.4E-46 T 13-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 Astex_0116 5460f040d91acaaf5e358e78ab6eb59e 157 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 54 70 - T 13-10-2018 IPR002178 PTS EIIA type-2 domain Astex_0116 5460f040d91acaaf5e358e78ab6eb59e 157 SUPERFAMILY SSF55804 1 150 4.45E-35 T 13-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 Astex_1712 47d73794ed6fe8475feb71f6460e28e0 172 Pfam PF07323 Protein of unknown function (DUF1465) 18 169 2.7E-59 T 13-10-2018 IPR010848 Protein of unknown function DUF1465 Astex_1712 47d73794ed6fe8475feb71f6460e28e0 172 Gene3D G3DSA:1.10.8.930 17 148 8.4E-50 T 13-10-2018 IPR038301 AraC-like superfamily Astex_2348 d2d6bb7b4efa26cdde97b3a1e04e3f3d 515 SUPERFAMILY SSF48452 347 477 3.37E-9 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_2348 d2d6bb7b4efa26cdde97b3a1e04e3f3d 515 Gene3D G3DSA:1.25.40.10 270 509 3.7E-9 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 Astex_1332 8ee272c2a0b444b7cb92bb59832be988 415 Pfam PF04610 TrbL/VirB6 plasmid conjugal transfer protein 57 292 2.0E-32 T 13-10-2018 IPR007688 Plasmid conjugal transfer TrbL/VirB6 GO:0030255 Astex_1211 63358ee5f6742ebb64583d9793d864bb 707 Pfam PF13779 Domain of unknown function (DUF4175) 39 361 4.4E-11 T 13-10-2018 IPR012683 Conserved hypothetical protein CHP02302, transmembrane Astex_1191 33055d167db31ad29a2e921c6bbec654 151 Pfam PF06793 Uncharacterised protein family (UPF0262) 2 150 1.9E-62 T 13-10-2018 IPR008321 Uncharacterised conserved protein UCP032146 Astex_0590 0716f7adc6a8cb3b799bf54d7d21a4c9 472 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 6 453 1.1E-74 T 13-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G Astex_0590 0716f7adc6a8cb3b799bf54d7d21a4c9 472 SUPERFAMILY SSF117143 82 432 2.48E-52 T 13-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like Astex_0590 0716f7adc6a8cb3b799bf54d7d21a4c9 472 Pfam PF07559 Flagellar basal body protein FlaE 210 351 8.4E-10 T 13-10-2018 IPR011491 Flagellar hook protein FlgE Astex_0590 0716f7adc6a8cb3b799bf54d7d21a4c9 472 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 393 470 2.3E-17 T 13-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain Astex_0326 a258ba3f50c7cb8ed047222a954f9082 99 Pfam PF01844 HNH endonuclease 33 83 5.0E-6 T 13-10-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 Astex_0887 7d5ae9fce35f3ef5109a21f463d66fa4 182 Pfam PF02592 Putative vitamin uptake transporter 82 152 3.4E-10 T 13-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 Astex_1904 0594d6a5187d438c802061f3e8f79bdb 399 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 2 384 6.2E-120 T 13-10-2018 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 Astex_1983 0e5f65d3d7d711a210c37245617c0288 130 Pfam PF03203 MerC mercury resistance protein 14 121 2.4E-20 T 13-10-2018 IPR004891 Mercury transport protein MerC GO:0015097|GO:0015694|GO:0016020 Astex_3644 91073cb59061ae32796a73430f7cd707 205 TIGRFAM TIGR03424 urea_degr_1: urea carboxylase-associated protein 1 7 203 1.2E-100 T 13-10-2018 IPR017791 Urea carboxylase-associated protein 1 Astex_3644 91073cb59061ae32796a73430f7cd707 205 Pfam PF09347 Domain of unknown function (DUF1989) 11 176 6.2E-60 T 13-10-2018 IPR018959 Protein of unknown function DUF1989 Astex_0204 eaf34b5aa16a65c8f736a554f67e5105 192 Pfam PF13302 Acetyltransferase (GNAT) domain 18 153 1.8E-26 T 13-10-2018 IPR000182 GNAT domain Astex_0204 eaf34b5aa16a65c8f736a554f67e5105 192 SUPERFAMILY SSF55729 11 153 1.14E-34 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase Astex_0204 eaf34b5aa16a65c8f736a554f67e5105 192 Gene3D G3DSA:3.40.630.30 6 161 7.4E-39 T 13-10-2018 Astex_2243 5f8e8c1646ad31495d686906764fe95a 110 Pfam PF05101 Type IV secretory pathway, VirB3-like protein 5 95 1.1E-21 T 13-10-2018 IPR007792 Type IV secretion system, VirB3 / TrbD / AvhB Astex_1878 7608b1b16c90e329cf9e43ce92c296c6 221 Gene3D G3DSA:2.40.160.170 22 220 1.1E-40 T 13-10-2018 Astex_2182 3beb1b21901a5e8f98fed90b283263f7 141 Pfam PF04892 VanZ like family 46 105 2.9E-7 T 13-10-2018 IPR006976 VanZ-like Astex_2838 9a3d0b5955934e23768eb9d44bb54e21 85 Pfam PF07330 Protein of unknown function (DUF1467) 1 82 4.4E-27 T 13-10-2018 IPR009935 Protein of unknown function DUF1467 Astex_3183 d4c5361ec0165b177c6f08cff1416cf8 120 TIGRFAM TIGR04433 UrcA_uranyl: UrcA family protein 5 92 2.1E-13 T 13-10-2018 IPR030972 UrcA family protein Astex_1830 39ce9055ac401f365d238ee5a5da7e31 271 Pfam PF11927 Protein of unknown function (DUF3445) 73 224 7.5E-41 T 13-10-2018 IPR021848 Protein of unknown function DUF3445 Astex_1786 f04590dc15c3164f0e561d762aefe14d 384 Pfam PF01098 Cell cycle protein 27 371 1.3E-74 T 13-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 Astex_3771 0f22a3d6c0cbe3e8bbe22062323138f4 299 PIRSF PIRSF037112 5 298 6.8E-77 T 13-10-2018 IPR017113 Antirestriction, ArdC Astex_3771 0f22a3d6c0cbe3e8bbe22062323138f4 299 Pfam PF08401 Domain of unknown function (DUF1738) 13 108 6.7E-27 T 13-10-2018 IPR013610 Domain of unknown function DUF1738 Astex_3574 8c29552da9ad2a9074820d9919807c33 300 Gene3D G3DSA:3.20.20.150 1 289 8.3E-75 T 13-10-2018 Astex_3574 8c29552da9ad2a9074820d9919807c33 300 SUPERFAMILY SSF51658 5 281 1.31E-56 T 13-10-2018 IPR036237 Xylose isomerase-like superfamily Astex_3574 8c29552da9ad2a9074820d9919807c33 300 TIGRFAM TIGR04379 myo_inos_iolE: myo-inosose-2 dehydratase 3 288 7.8E-123 T 13-10-2018 IPR030823 IolE/MocC family KEGG: 00562+4.2.1.44 Astex_3574 8c29552da9ad2a9074820d9919807c33 300 Pfam PF01261 Xylose isomerase-like TIM barrel 30 221 2.6E-24 T 13-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain Astex_0578 b399f28a2acde299be418819b2a17f7c 98 Gene3D G3DSA:1.10.1220.10 2 50 2.9E-9 T 13-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 Astex_0578 b399f28a2acde299be418819b2a17f7c 98 Pfam PF04221 RelB antitoxin 4 52 1.8E-11 T 13-10-2018 IPR007337 RelB antitoxin/Antitoxin DinJ Astex_0526 9b0519a239f01df75d62bd5ff52a3c45 212 Pfam PF01694 Rhomboid family 53 203 3.6E-22 T 13-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 Astex_0526 9b0519a239f01df75d62bd5ff52a3c45 212 SUPERFAMILY SSF144091 8 208 1.1E-24 T 13-10-2018 Astex_0526 9b0519a239f01df75d62bd5ff52a3c45 212 Gene3D G3DSA:1.20.1540.10 9 207 1.4E-17 T 13-10-2018 IPR035952 Rhomboid-like superfamily Astex_1892 0b1c5e9656f6968a4ab6633c616f47f1 449 SUPERFAMILY SSF103473 8 436 7.46E-33 T 13-10-2018 IPR036259 MFS transporter superfamily Astex_1892 0b1c5e9656f6968a4ab6633c616f47f1 449 Pfam PF07690 Major Facilitator Superfamily 24 388 4.0E-15 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 Astex_1892 0b1c5e9656f6968a4ab6633c616f47f1 449 Gene3D G3DSA:1.20.1250.20 226 438 3.8E-43 T 13-10-2018 Astex_1892 0b1c5e9656f6968a4ab6633c616f47f1 449 Gene3D G3DSA:1.20.1250.20 14 219 5.5E-40 T 13-10-2018 Astex_2411 1b9755e9eb4da379952a547a1c925a91 523 SUPERFAMILY SSF53474 149 500 5.59E-15 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1752 f749df85e1e751e2f70920dedd093e27 82 Pfam PF13467 Ribbon-helix-helix domain 5 65 9.4E-22 T 13-10-2018 IPR027373 Ribbon-helix-helix domain Astex_1752 f749df85e1e751e2f70920dedd093e27 82 Gene3D G3DSA:1.10.3990.20 3 81 6.3E-15 T 13-10-2018 IPR038268 Ribbon-helix-helix domain superfamily Astex_1708 be0ac8cfe5deefc162b7afa635bf9580 236 Pfam PF06242 Protein of unknown function (DUF1013) 34 172 4.4E-64 T 13-10-2018 IPR010421 Protein of unknown function DUF1013 Astex_2809 773248a5b3c08b5d9de8459c61c063ee 146 Pfam PF05154 TM2 domain 66 115 9.4E-14 T 13-10-2018 IPR007829 TM2 domain Astex_0371 800852bc1ed256cc1c893db2d0e346e1 114 Pfam PF10984 Protein of unknown function (DUF2794) 18 102 3.1E-36 T 13-10-2018 IPR021252 Protein of unknown function DUF2794 Astex_2084 adc1f11ac64ce072432ae142dfb06b77 265 Pfam PF02673 Bacitracin resistance protein BacA 6 255 5.5E-75 T 13-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 Astex_2084 adc1f11ac64ce072432ae142dfb06b77 265 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 6 254 1.0E-70 T 13-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 Astex_2084 adc1f11ac64ce072432ae142dfb06b77 265 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 261 16.861 T 13-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 Astex_0853 a8327190ee6c6526cd722147d2f20593 376 PIRSF PIRSF031773 1 375 3.7E-74 T 13-10-2018 IPR005891 DevC protein Astex_0853 a8327190ee6c6526cd722147d2f20593 376 Pfam PF12704 MacB-like periplasmic core domain 18 224 4.0E-8 T 13-10-2018 IPR025857 MacB-like periplasmic core domain Astex_1218 3cbb46ecb074a128e49077768e21fa1c 243 SUPERFAMILY SSF53474 19 241 8.38E-29 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_1218 3cbb46ecb074a128e49077768e21fa1c 243 Gene3D G3DSA:3.40.50.1820 35 243 1.5E-51 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold Astex_2265 5440f12aeedadff7b79e908ae0df66c6 380 SUPERFAMILY SSF51197 148 312 1.71E-6 T 13-10-2018 Astex_0025 c78839c0c7d5ce919b746d44eaea5bdb 100 Gene3D G3DSA:1.20.5.780 5 89 4.5E-11 T 13-10-2018 Astex_0025 c78839c0c7d5ce919b746d44eaea5bdb 100 Pfam PF08681 Protein of unknown function (DUF1778) 14 87 8.9E-15 T 13-10-2018 IPR014795 Vibrio phage ICP1, Orf50 Astex_0025 c78839c0c7d5ce919b746d44eaea5bdb 100 SUPERFAMILY SSF47598 8 85 6.12E-17 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 Astex_0537 48260b7a551d65c742bf8fa041413b9b 89 ProDom PD029395 PLASMID MOBILIZATION C MOBILITY CONJUGATION MOBC MOBS ORF94 PROBABLE ORF110 7 79 3.0E-19 T 13-10-2018 Astex_3446 ce709cf6996384b6bc9d7a14997be3c7 278 Pfam PF04228 Putative neutral zinc metallopeptidase 3 276 1.2E-100 T 13-10-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative Astex_3419 9e4705e709e17bb1cd3c518c8b0ef527 418 Pfam PF11902 Protein of unknown function (DUF3422) 6 415 2.3E-121 T 13-10-2018 IPR021830 Protein of unknown function DUF3422 Astex_1398 55357e5fd41c27fbc5316ce298b94271 533 Pfam PF03806 AbgT putative transporter family 16 529 6.9E-209 T 13-10-2018 IPR004697 p-Aminobenzoyl-glutamate transport protein AbgT GO:0015558|GO:1902604 Astex_2390 3f6ba15fddfc127d1a197d4664e873df 456 Pfam PF03050 Transposase IS66 family 162 422 1.0E-51 T 13-10-2018 IPR004291 Transposase, IS66 Astex_3658 1f7028dc323de0a69c24816495f1d255 97 Pfam PF13560 Helix-turn-helix domain 4 57 4.2E-7 T 13-10-2018 Astex_3658 1f7028dc323de0a69c24816495f1d255 97 Gene3D G3DSA:1.10.260.40 1 67 5.2E-11 T 13-10-2018 Astex_3658 1f7028dc323de0a69c24816495f1d255 97 SUPERFAMILY SSF47413 2 57 1.91E-8 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 Astex_0907 a961236de7a90bbc681ac245463cd72f 262 Pfam PF07277 SapC 24 247 2.4E-62 T 13-10-2018 IPR010836 SapC Astex_0374 fe3add100c14ef81de70b3a55100ab15 249 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 24 244 6.4E-52 T 13-10-2018 IPR006214 Bax inhibitor 1-related Astex_1925 b2fa4ee6c06d22ddcd3e86291c20051b 131 Gene3D G3DSA:2.40.128.200 57 130 4.6E-10 T 13-10-2018 IPR036328 C-type lysozyme inhibitor superfamily Astex_1925 b2fa4ee6c06d22ddcd3e86291c20051b 131 Pfam PF09864 Membrane-bound lysozyme-inhibitor of c-type lysozyme 63 124 8.3E-8 T 13-10-2018 IPR018660 C-type lysozyme inhibitor Astex_1925 b2fa4ee6c06d22ddcd3e86291c20051b 131 SUPERFAMILY SSF141488 59 120 6.54E-8 T 13-10-2018 IPR036328 C-type lysozyme inhibitor superfamily Astex_3199 522d35dda3faa0934c705a2312fbafe3 41 Pfam PF08085 Entericidin EcnA/B family 20 39 6.7E-9 T 13-10-2018 IPR012556 Entericidin A/B GO:0009636|GO:0016020 Astex_0506 ba58f014d97beb50c77bace842b3e0ab 178 Pfam PF13779 Domain of unknown function (DUF4175) 26 99 2.0E-7 T 13-10-2018 IPR012683 Conserved hypothetical protein CHP02302, transmembrane Astex_2241 6df075a77d9798e0f061a5d86562dbde 351 Pfam PF04610 TrbL/VirB6 plasmid conjugal transfer protein 39 255 5.7E-36 T 13-10-2018 IPR007688 Plasmid conjugal transfer TrbL/VirB6 GO:0030255 Astex_0890 137dad36dfdbed305fe3b8222450c3f9 134 Pfam PF09912 Uncharacterized protein conserved in bacteria (DUF2141) 32 129 3.1E-29 T 13-10-2018 IPR018673 Protein of unknown function DUF2141 Astex_3443 58606c1b1bfa8d7690dff1d1939621b4 238 Pfam PF13386 Cytochrome C biogenesis protein transmembrane region 28 212 4.3E-35 T 13-10-2018 IPR039447 Urease accessory protein UreH-like, transmembrane domain Astex_2931 40c101e3e8d4035dc5bebfb2878e361a 178 Pfam PF02620 Uncharacterized ACR, COG1399 67 151 4.0E-8 T 13-10-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD Astex_0811 c34384eb95a71a0909c9c350ce7d71fd 172 Pfam PF05656 Protein of unknown function (DUF805) 15 158 8.6E-17 T 13-10-2018 IPR008523 Protein of unknown function DUF805 GO:0016021 Astex_1294 8156ab1aba959f88977e728ed0e7948b 168 PIRSF PIRSF014995 2 168 8.5E-48 T 13-10-2018 IPR014469 Protein of unknown function DUF2271 Astex_1294 8156ab1aba959f88977e728ed0e7948b 168 Pfam PF10029 Predicted periplasmic protein (DUF2271) 25 160 1.4E-44 T 13-10-2018 IPR014469 Protein of unknown function DUF2271 Astex_2733 1003ff9d261b46458dcbdf608e03409e 123 Pfam PF05656 Protein of unknown function (DUF805) 7 120 1.1E-22 T 13-10-2018 IPR008523 Protein of unknown function DUF805 GO:0016021 Astex_2752 c45e8c2eea3049866522ed630a9b9dfa 193 Pfam PF04519 Polymer-forming cytoskeletal 59 152 2.6E-23 T 13-10-2018 IPR007607 Bactofilin A/B Astex_2193 76fc81684a22a12e9339d83e7840ee63 414 Pfam PF04932 O-Antigen ligase 214 351 5.9E-15 T 13-10-2018 IPR007016 O-antigen ligase-related Astex_1119 fe40cc3f767684ad20d86d905c2c489a 307 Pfam PF01963 TraB family 43 304 5.3E-25 T 13-10-2018 IPR002816 Pheromone shutdown, TraB Astex_0723 49c07446ead20e9ea858ae7d947d64c3 104 Pfam PF04341 Protein of unknown function, DUF485 12 100 2.2E-33 T 13-10-2018 IPR007436 Protein of unknown function DUF485 Astex_3110 746bed706fe1096e75bb4f10046d86ed 136 Pfam PF07309 Flagellar protein FlaF 3 113 2.5E-36 T 13-10-2018 IPR010845 Flagellar FlaF GO:0044781 Astex_0712 530ed29d00f181640a2bef85dbc4d8a8 93 Pfam PF13710 ACT domain 13 73 1.1E-13 T 13-10-2018 Astex_3529 06ad9eac570141176ffefdae32c745cb 151 Pfam PF11911 Protein of unknown function (DUF3429) 12 148 1.3E-24 T 13-10-2018 IPR021836 Protein of unknown function DUF3429 Astex_2414 9cc4fe9e1e296de99cf9ae5bb1cb8ca2 252 Pfam PF04397 LytTr DNA-binding domain 153 241 1.9E-15 T 13-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 Astex_2414 9cc4fe9e1e296de99cf9ae5bb1cb8ca2 252 SMART SM00850 148 244 2.4E-14 T 13-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 Astex_1104 b939eba824b1e555aac2ee68182a9e1b 75 Pfam PF13453 Transcription factor zinc-finger 6 43 2.0E-14 T 13-10-2018 IPR027392 Transcription factor zinc-finger Astex_1248 e7bf27f46d609a7f2d473ccbd1a3e9d9 409 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 27 71 7.1E-9 T 13-10-2018 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal Astex_1342 5340b53606ecedb6b2e0e0092e831c91 404 Pfam PF13372 Alginate export 49 266 2.5E-12 T 13-10-2018 IPR025388 Alginate export domain Astex_0619 0f72e98223c86d87c6e229798c1c5256 424 Pfam PF10098 Uncharacterised protein conserved in bacteria (DUF2336) 110 378 6.8E-60 T 13-10-2018 IPR019285 Protein of unknown function DUF2336 Astex_2178 d772ec43015c8417f0d5f957d3cfbdd2 515 Pfam PF07394 Protein of unknown function (DUF1501) 44 494 7.5E-49 T 13-10-2018 IPR010869 Protein of unknown function DUF1501 Astex_1978 30a68e333248b968ec8ae15ade25f4fa 658 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 73 230 3.3E-18 T 13-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like Astex_2367 8cbba898c6f059c6b52a1a93601e6e5b 162 TIGRFAM TIGR02300 FYDLN_acid: TIGR02300 family protein 2 156 6.7E-27 T 13-10-2018 IPR012644 Conserved hypothetical protein CHP02300, FYDLN acid Astex_2367 8cbba898c6f059c6b52a1a93601e6e5b 162 Pfam PF09538 Protein of unknown function (FYDLN_acid) 2 141 3.6E-21 T 13-10-2018 IPR012644 Conserved hypothetical protein CHP02300, FYDLN acid Astex_1232 9c99de4dae4531650ccde87e89a181ab 780 SUPERFAMILY SSF48208 273 717 6.6E-16 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 Astex_1232 9c99de4dae4531650ccde87e89a181ab 780 Gene3D G3DSA:1.50.10.10 338 625 8.6E-6 T 13-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 Astex_1174 8726801f2d883cc857d1b7f028188c17 153 Pfam PF05656 Protein of unknown function (DUF805) 55 141 2.9E-23 T 13-10-2018 IPR008523 Protein of unknown function DUF805 GO:0016021 Astex_0316 069fbe4ad83026246823643ac482ed0e 233 Gene3D G3DSA:2.10.109.10 119 233 4.9E-7 T 13-10-2018 Astex_0316 069fbe4ad83026246823643ac482ed0e 233 SUPERFAMILY SSF51306 133 231 9.94E-14 T 13-10-2018 IPR036286 LexA/Signal peptidase-like superfamily Astex_1605 0a201addf42c506d54e9a18f69063d97 62 Pfam PF10055 Uncharacterized small protein (DUF2292) 17 52 6.9E-18 T 13-10-2018 IPR018743 Protein of unknown function DUF2292 Astex_3105 e1525fef4a29a5d9234a4290dd15f915 966 SUPERFAMILY SSF101898 426 634 2.09E-5 T 13-10-2018 Astex_2933 040dd147ee354dd78ed43aa3aea511dc 163 Pfam PF04355 SmpA / OmlA family 40 103 5.2E-11 T 13-10-2018 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 Astex_1473 5311a2ba03c95398a2b602d6efb89c11 89 ProDom PD029395 PLASMID MOBILIZATION C MOBILITY CONJUGATION MOBC MOBS ORF94 PROBABLE ORF110 7 79 2.0E-18 T 13-10-2018 Astex_1468 b4a7181c2ef83fdd26a6dda14ee1578e 128 Pfam PF09361 Phasin protein 25 114 3.2E-6 T 13-10-2018 IPR018968 Phasin Astex_0888 d33ea560c046976171c481f9ffedb762 420 Pfam PF02646 RmuC family 104 394 1.3E-89 T 13-10-2018 IPR003798 DNA recombination RmuC Astex_2887 0289a3ad6c1608879bbb83d587245b94 393 Pfam PF11288 Protein of unknown function (DUF3089) 98 302 2.1E-59 T 13-10-2018 IPR021440 Protein of unknown function DUF3089 Astex_0771 61fb891d9cccb8ad818b74301c885359 289 SUPERFAMILY SSF56059 94 260 3.39E-14 T 13-10-2018 Astex_0987 5efd542a197d6650cacafb8bb1fb617d 439 SUPERFAMILY SSF51126 122 388 7.63E-9 T 13-10-2018 IPR011050 Pectin lyase fold/virulence factor Astex_0297 a541381777412e7d52bcedc3ea09bc2d 159 Pfam PF13274 Protein of unknown function (DUF4065) 26 126 2.6E-22 T 13-10-2018 IPR025272 Domain of unknown function DUF4065 Astex_3571 80d3cd8ddbad00d1d27703c5ee5e5ee5 367 Pfam PF10134 Replication initiator protein A 27 260 4.8E-72 T 13-10-2018 IPR018777 Replication initiator protein A Astex_0447 85e93373458d75385e0b0e979c94fec9 192 Pfam PF09998 Uncharacterized protein conserved in bacteria (DUF2239) 7 182 1.1E-65 T 13-10-2018 IPR018715 Protein of unknown function DUF2239 Astex_1271 baa05c16c2084ad0f3ae2be2c9a788b3 586 Pfam PF05960 Bacterial protein of unknown function (DUF885) 60 570 5.3E-153 T 13-10-2018 IPR010281 Protein of unknown function DUF885 Astex_0598 bf8eef6859110f71913a1ee0b7578ee9 123 Pfam PF01219 Prokaryotic diacylglycerol kinase 15 113 1.3E-31 T 13-10-2018 IPR000829 DAGK family GO:0008654|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 Astex_0598 bf8eef6859110f71913a1ee0b7578ee9 123 Gene3D G3DSA:1.10.3830.10 4 120 3.8E-35 T 13-10-2018 IPR036945 Diacylglycerol kinase (DAGK) superfamily GO:0008610|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 Astex_1128 4bd015034de855ff14c49134a9cd30b6 197 Pfam PF05656 Protein of unknown function (DUF805) 13 183 8.6E-29 T 13-10-2018 IPR008523 Protein of unknown function DUF805 GO:0016021 Astex_0048 a1f5056372d467b2fab410a4a08a5101 173 Pfam PF11188 Protein of unknown function (DUF2975) 55 173 2.7E-11 T 13-10-2018 IPR021354 Protein of unknown function DUF2975 Astex_1735 052fa489ce8636f69de5d747b35228de 401 Pfam PF07786 Protein of unknown function (DUF1624) 18 227 3.0E-11 T 13-10-2018 IPR012429 Domain of unknown function DUF1624 Reactome: R-HSA-2024096|Reactome: R-HSA-2206291|Reactome: R-HSA-6798695 Astex_0008 27c81fd99179faed37ce964f94f00d74 166 Pfam PF09965 Uncharacterized protein conserved in bacteria (DUF2199) 7 152 7.4E-47 T 13-10-2018 IPR018697 Protein of unknown function DUF2199 Astex_2111 ade26ca71bc7886f93922190fe62e4a4 168 SUPERFAMILY SSF141371 45 125 2.75E-5 T 13-10-2018 Astex_2491 572d277d5c557493e6594ecc9cde83a9 79 Pfam PF12728 Helix-turn-helix domain 23 70 1.0E-6 T 13-10-2018 Astex_2200 16f1a3ecee1961c326b027e3a004b137 131 Pfam PF05717 IS66 Orf2 like protein 9 105 1.4E-36 T 13-10-2018 IPR008878 Transposase IS66, Orf2 Astex_2728 11609b3ccc425164bd6e8cc4514c762d 802 SUPERFAMILY SSF55545 76 128 3.14E-6 T 13-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 Astex_1917 7f24f395848fad3986f906fd76da7920 79 Pfam PF11391 Protein of unknown function (DUF2798) 17 73 4.6E-19 T 13-10-2018 IPR021529 Protein of unknown function DUF2798 Astex_2739 71afcb8d1bb9e14ba9643114129af9e9 116 Pfam PF04304 Protein of unknown function (DUF454) 2 114 3.8E-30 T 13-10-2018 IPR007401 Protein of unknown function DUF454 Astex_2331 cfcd000b2741f8614f3db7e2739d17fb 316 Pfam PF01963 TraB family 48 312 8.3E-32 T 13-10-2018 IPR002816 Pheromone shutdown, TraB Astex_1753 debd0e6c5773e98cdfe009095b9457f9 65 Pfam PF13770 Domain of unknown function (DUF4169) 2 56 7.3E-17 T 13-10-2018 IPR025227 Protein of unknown function DUF4169 Astex_0429 b0a429a781e82612cba9a7996855532b 187 Pfam PF07811 TadE-like protein 31 71 4.1E-8 T 13-10-2018 IPR012495 TadE-like Astex_3505 a1dddfd1cfd92bd7bd8f6f302f0ea85b 72 Pfam PF09866 Uncharacterized protein conserved in bacteria (DUF2093) 24 65 6.5E-22 T 13-10-2018 IPR018661 Protein of unknown function DUF2093 Astex_0096 a627d7fe8172f18eb3d5ae4bff73d43b 456 Pfam PF03050 Transposase IS66 family 162 422 1.7E-52 T 13-10-2018 IPR004291 Transposase, IS66