locus-tag	class	description
EM6_0001	COG0018	arginyl-trna synthetase
EM6_0003	COG0450	alkyl hydroperoxide reductase
EM6_0010	COG1872	DUF167
EM6_0011	COG0473	3-isopropylmalate dehydrogenase activity
EM6_0013	COG0066	3-isopropylmalate dehydratase activity
EM6_0014	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EM6_0016	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EM6_0019	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EM6_0021	COG0129	dihydroxy-acid dehydratase activity
EM6_0026	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EM6_0027	COG3162	membrane
EM6_0037	COG0181	hydroxymethylbilane synthase activity
EM6_0039	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EM6_0040	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EM6_0043	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EM6_0049	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EM6_0053	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EM6_0055	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EM6_0057	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EM6_0059	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EM6_0063	COG0640	Transcriptional regulator
EM6_0067	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EM6_0069	COG0189	ligase activity
EM6_0069	COG4067	protein conserved in archaea
EM6_0072	COG4974	Belongs to the 'phage' integrase family
EM6_0079	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EM6_0081	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EM6_0086	COG3384	dioxygenase
EM6_0087	COG2353	YceI-like domain
EM6_0088	COG4771	TonB-dependent receptor
EM6_0089	COG0295	cytidine deaminase activity
EM6_0091	COG0469	pyruvate kinase activity
EM6_0095	COG1940	carbohydrate kinase activity
EM6_0096	COG2272	Belongs to the type-B carboxylesterase lipase family
EM6_0102	COG2308	Evidence 4 Homologs of previously reported genes of
EM6_0110	COG1959	2 iron, 2 sulfur cluster binding
EM6_0112	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
EM6_0117	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EM6_0119	COG3422	double-strand break repair
EM6_0121	COG2226	methyltransferase
EM6_0124	COG1410	methionine synthase
EM6_0124	COG0646	methionine synthase
EM6_0125	COG1181	Belongs to the D-alanine--D-alanine ligase family
EM6_0128	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EM6_0131	COG0167	dihydroorotate dehydrogenase activity
EM6_0133	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EM6_0134	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
EM6_0135	COG4786	Flagellar basal body rod
EM6_0136	COG4786	Flagellar basal body rod
EM6_0139	COG1136	(ABC) transporter
EM6_0144	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EM6_0145	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EM6_0146	COG0783	Belongs to the Dps family
EM6_0150	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EM6_0159	COG2885	chlorophyll binding
EM6_0160	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EM6_0163	COG2957	Belongs to the agmatine deiminase family
EM6_0165	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EM6_0166	COG0840	transmembrane signaling receptor activity
EM6_0170	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EM6_0171	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EM6_0173	COG1322	Protein conserved in bacteria
EM6_0176	COG0242	peptide deformylase activity
EM6_0177	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EM6_0178	COG0101	tRNA pseudouridine synthase activity
EM6_0179	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EM6_0185	COG2755	lipolytic protein G-D-S-L family
EM6_0185	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EM6_0187	COG0598	Magnesium transport protein CorA
EM6_0191	COG4206	TonB-dependent receptor
EM6_0195	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EM6_0196	COG5001	Diguanylate cyclase
EM6_0198	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EM6_0201	COG0588	phosphoglycerate mutase activity
EM6_0202	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EM6_0202	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EM6_0205	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EM6_0208	COG1294	oxidase, subunit
EM6_0210	COG1086	Polysaccharide biosynthesis protein
EM6_0212	COG0314	molybdopterin synthase activity
EM6_0213	COG0315	cyclic pyranopterin monophosphate synthase activity
EM6_0214	COG2264	protein methyltransferase activity
EM6_0216	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EM6_0222	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EM6_0225	COG0494	nUDIX hydrolase
EM6_0230	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EM6_0231	COG0706	membrane insertase activity
EM6_0232	COG0594	ribonuclease P activity
EM6_0233	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EM6_0237	COG0072	phenylalanine-tRNA ligase activity
EM6_0237	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EM6_0238	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EM6_0240	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EM6_0241	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EM6_0244	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EM6_0248	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EM6_0249	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EM6_0254	COG0351	phosphomethylpyrimidine kinase
EM6_0257	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EM6_0262	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EM6_0266	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EM6_0267	COG0564	pseudouridine synthase activity
EM6_0268	COG0848	biopolymer transport protein
EM6_0269	COG0302	gtp cyclohydrolase
EM6_0270	COG0215	cysteine-tRNA ligase activity
EM6_0275	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EM6_0276	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EM6_0279	COG0657	acetylesterase activity
EM6_0279	COG2755	lipolytic protein G-D-S-L family
EM6_0283	COG0210	DNA helicase
EM6_0284	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EM6_0291	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EM6_0295	COG1994	Peptidase M50
EM6_0300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EM6_0301	COG0174	glutamine synthetase
EM6_0304	COG3345	alpha-galactosidase
EM6_0306	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EM6_0309	COG2079	MmgE PrpD family protein
EM6_0317	COG0861	Integral membrane protein TerC family
EM6_0318	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EM6_0319	COG1692	metallophosphoesterase
EM6_0320	COG0217	transcriptional regulatory protein
EM6_0325	COG0768	penicillin binding
EM6_0326	COG0772	Belongs to the SEDS family
EM6_0329	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EM6_0330	COG0405	Gamma-glutamyltransferase
EM6_0332	COG0840	transmembrane signaling receptor activity
EM6_0337	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EM6_0340	COG0405	Gamma-glutamyltransferase
EM6_0342	COG0438	transferase activity, transferring glycosyl groups
EM6_0343	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EM6_0345	COG0542	response to heat
EM6_0346	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EM6_0347	COG0142	geranyltranstransferase activity
EM6_0350	COG0322	excinuclease ABC activity
EM6_0355	COG3047	cAMP biosynthetic process
EM6_0362	COG0483	inositol monophosphate 1-phosphatase activity
EM6_0363	COG1396	sequence-specific DNA binding
EM6_0364	COG0612	Peptidase, M16
EM6_0367	COG2264	protein methyltransferase activity
EM6_0369	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EM6_0381	COG0670	Belongs to the BI1 family
EM6_0383	COG2205	protein histidine kinase activity
EM6_0388	COG2239	Acts as a magnesium transporter
EM6_0390	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EM6_0393	COG0356	it plays a direct role in the translocation of protons across the membrane
EM6_0398	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EM6_0400	COG1194	a g-specific adenine glycosylase
EM6_0402	COG2189	Belongs to the N(4) N(6)-methyltransferase family
EM6_0403	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EM6_0404	COG3152	Membrane
EM6_0405	COG0354	folic acid binding
EM6_0407	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EM6_0409	COG1024	Enoyl-CoA hydratase
EM6_0412	COG0617	tRNA 3'-terminal CCA addition
EM6_0415	COG0408	coproporphyrinogen oxidase activity
EM6_0416	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EM6_0417	COG0723	plastoquinol--plastocyanin reductase activity
EM6_0419	COG2857	Cytochrome c1
EM6_0419	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EM6_0420	COG1418	mRNA catabolic process
EM6_0421	COG0012	GTP binding
EM6_0423	COG1819	glycosyl
EM6_0425	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EM6_0427	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EM6_0431	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EM6_0439	COG1846	Transcriptional regulator
EM6_0440	COG1764	response to oxidative stress
EM6_0441	COG0667	Aldo Keto reductase
EM6_0443	COG0626	cystathionine gamma-synthase activity
EM6_0448	COG0460	homoserine dehydrogenase
EM6_0450	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EM6_0453	COG0393	Putative heavy-metal-binding
EM6_0458	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EM6_0460	COG5328	Belongs to the UPF0262 family
EM6_0462	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EM6_0463	COG0424	maF-like protein
EM6_0465	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
EM6_0500	COG1196	nuclear chromosome segregation
EM6_0500	COG0741	lytic transglycosylase activity
EM6_0500	COG0739	heme binding
EM6_0508	COG0582	viral genome integration into host DNA
EM6_0510	COG0513	Belongs to the DEAD box helicase family
EM6_0518	COG0582	viral genome integration into host DNA
EM6_0519	COG5489	Protein of unknown function (DUF736)
EM6_0521	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EM6_0522	COG2271	Major facilitator Superfamily
EM6_0524	COG0583	DNA-binding transcription factor activity
EM6_0525	COG4771	TonB-dependent receptor
EM6_0526	COG2971	BadF BadG BcrA BcrD
EM6_0527	COG3142	Participates in the control of copper homeostasis
EM6_0531	COG1472	Belongs to the glycosyl hydrolase 3 family
EM6_0534	COG3537	Alpha-1,2-mannosidase
EM6_0548	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EM6_0551	COG3338	carbonate dehydratase activity
EM6_0552	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EM6_0557	COG1706	bacterial-type flagellum-dependent cell motility
EM6_0559	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EM6_0562	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EM6_0565	COG0616	signal peptide processing
EM6_0571	COG1136	(ABC) transporter
EM6_0572	COG0523	cobalamin synthesis protein
EM6_0574	COG3540	Alkaline phosphatase
EM6_0579	COG0640	Transcriptional regulator
EM6_0582	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EM6_0585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EM6_0586	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EM6_0587	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EM6_0588	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EM6_0590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EM6_0591	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EM6_0592	COG1522	sequence-specific DNA binding
EM6_0596	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EM6_0597	COG1309	transcriptional regulator
EM6_0599	COG0673	inositol 2-dehydrogenase activity
EM6_0607	COG4774	siderophore transport
EM6_0608	COG3128	pkhd-type hydroxylase
EM6_0612	COG1477	protein flavinylation
EM6_0615	COG3046	protein related to deoxyribodipyrimidine photolyase
EM6_0624	COG2755	lipolytic protein G-D-S-L family
EM6_0624	COG0657	acetylesterase activity
EM6_0628	COG3459	Glycosyltransferase 36 associated
EM6_0634	COG0726	polysaccharide deacetylase
EM6_0636	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EM6_0641	COG1473	amidohydrolase
EM6_0642	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EM6_0645	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
EM6_0649	COG3451	type IV secretory pathway VirB4
EM6_0652	COG0741	lytic transglycosylase activity
EM6_0655	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EM6_0656	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EM6_0660	COG2132	Multicopper oxidase
EM6_0663	COG1609	Transcriptional regulator
EM6_0664	COG0477	Major facilitator Superfamily
EM6_0666	COG2205	protein histidine kinase activity
EM6_0666	COG0784	Response regulator, receiver
EM6_0667	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EM6_0669	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EM6_0670	COG0805	protein transport
EM6_0671	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EM6_0672	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EM6_0673	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EM6_0674	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EM6_0675	COG1472	Belongs to the glycosyl hydrolase 3 family
EM6_0679	COG1793	dna ligase
EM6_0680	COG1793	dna ligase
EM6_0680	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EM6_0681	COG1201	RNA secondary structure unwinding
EM6_0684	COG0583	DNA-binding transcription factor activity
EM6_0692	COG3867	Arabinogalactan endo-beta-1,4-galactanase
EM6_0696	COG3250	beta-galactosidase activity
EM6_0697	COG3250	beta-galactosidase activity
EM6_0700	COG1462	curli production assembly transport component CsgG
EM6_0701	COG1462	curli production assembly transport component CsgG
EM6_0704	COG0784	Response regulator, receiver
EM6_0704	COG5002	protein histidine kinase activity
EM6_0704	COG2205	protein histidine kinase activity
EM6_0705	COG2211	Major facilitator Superfamily
EM6_0711	COG1609	Transcriptional regulator
EM6_0712	COG4191	Histidine kinase
EM6_0712	COG0784	Response regulator, receiver
EM6_0717	COG0714	Associated with various cellular activities
EM6_0721	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EM6_0727	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EM6_0728	COG0459	protein refolding
EM6_0731	COG0321	lipoyl(octanoyl) transferase activity
EM6_0732	COG3152	Membrane
EM6_0735	COG0564	pseudouridine synthase activity
EM6_0738	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EM6_0742	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EM6_0743	COG1278	Cold shock
EM6_0745	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
EM6_0748	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EM6_0750	COG0142	geranyltranstransferase activity
EM6_0751	COG1722	exodeoxyribonuclease VII activity
EM6_0753	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EM6_0756	COG1595	DNA-templated transcription, initiation
EM6_0759	COG1501	Belongs to the glycosyl hydrolase 31 family
EM6_0761	COG2186	Transcriptional regulator
EM6_0763	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EM6_0764	COG1684	flagellar biosynthetic protein fliR
EM6_0765	COG1987	bacterial-type flagellum assembly
EM6_0768	COG1677	Flagellar hook-basal body complex protein FliE
EM6_0769	COG1558	bacterial-type flagellum-dependent cell motility
EM6_0771	COG3190	flagellar
EM6_0772	COG1338	Plays a role in the flagellum-specific transport system
EM6_0784	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EM6_0785	COG0840	transmembrane signaling receptor activity
EM6_0786	COG0842	Transport permease protein
EM6_0787	COG1131	(ABC) transporter
EM6_0789	COG1309	transcriptional regulator
EM6_0792	COG2267	carboxylic ester hydrolase activity
EM6_0793	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EM6_0797	COG2824	Alkylphosphonate utilization operon protein PhnA
EM6_0800	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EM6_0803	COG0784	Response regulator, receiver
EM6_0803	COG2205	protein histidine kinase activity
EM6_0803	COG2198	Histidine kinase
EM6_0807	COG1566	PFAM secretion protein HlyD family protein
EM6_0809	COG1309	transcriptional regulator
EM6_0813	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
EM6_0817	COG1858	cytochrome C peroxidase
EM6_0822	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EM6_0830	COG0582	viral genome integration into host DNA
EM6_0831	COG3507	Belongs to the glycosyl hydrolase 43 family
EM6_0837	COG2948	multi-organism process
EM6_0841	COG0776	regulation of translation
EM6_0842	COG4957	zinc ion binding
EM6_0850	COG5489	Protein of unknown function (DUF736)
EM6_0852	COG3507	Belongs to the glycosyl hydrolase 43 family
EM6_0855	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EM6_0856	COG4948	Mandelate Racemase Muconate Lactonizing
EM6_0859	COG0823	Involved in the tonB-independent uptake of proteins
EM6_0859	COG1506	peptidase
EM6_0859	COG4946	Tricorn protease homolog
EM6_0865	COG2197	response regulator
EM6_0867	COG0840	transmembrane signaling receptor activity
EM6_0872	COG1278	Cold shock
EM6_0873	COG2813	Specifically methylates the guanine in position
EM6_0874	COG1187	pseudouridine synthase activity
EM6_0876	COG0745	RESPONSE REGULATOR receiver
EM6_0877	COG2205	protein histidine kinase activity
EM6_0879	COG0126	phosphoglycerate kinase activity
EM6_0882	COG0071	Belongs to the small heat shock protein (HSP20) family
EM6_0883	COG2378	regulation of single-species biofilm formation
EM6_0884	COG0626	cystathionine gamma-synthase activity
EM6_0885	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EM6_0887	COG4208	sulfate ABC transporter
EM6_0888	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EM6_0890	COG4206	TonB-dependent receptor
EM6_0891	COG0006	proline dipeptidase activity
EM6_0893	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EM6_0894	COG0497	DNA recombination
EM6_0895	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EM6_0896	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EM6_0897	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EM6_0899	COG0849	cell division
EM6_0900	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EM6_0904	COG0387	Pfam Sodium calcium exchanger
EM6_0906	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EM6_0907	COG0640	Transcriptional regulator
EM6_0908	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EM6_0912	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EM6_0922	COG1024	Enoyl-CoA hydratase
EM6_0922	COG1250	3-hydroxyacyl-CoA dehydrogenase
EM6_0923	COG0183	Belongs to the thiolase family
EM6_0925	COG3734	2-keto-3-deoxy-galactonokinase
EM6_0926	COG0800	Aldolase
EM6_0927	COG1733	regulation of RNA biosynthetic process
EM6_0928	COG0702	epimerase
EM6_0930	COG1051	belongs to the nudix hydrolase family
EM6_0935	COG1595	DNA-templated transcription, initiation
EM6_0938	COG1546	Belongs to the CinA family
EM6_0938	COG1058	Belongs to the CinA family
EM6_0939	COG1489	DNA binding
EM6_0940	COG0392	lysyltransferase activity
EM6_0940	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EM6_0942	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EM6_0953	COG0534	Mate efflux family protein
EM6_0954	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
EM6_0957	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EM6_0958	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EM6_0959	COG0546	phosphoglycolate phosphatase activity
EM6_0964	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EM6_0970	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EM6_0975	COG0784	Response regulator, receiver
EM6_0975	COG2205	protein histidine kinase activity
EM6_0975	COG5002	protein histidine kinase activity
EM6_0977	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EM6_0977	COG2022	thiamine diphosphate biosynthetic process
EM6_0983	COG0848	biopolymer transport protein
EM6_0984	COG0811	peptide transport
EM6_0985	COG2951	lytic endotransglycosylase activity
EM6_0989	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EM6_0990	COG3750	Belongs to the UPF0335 family
EM6_0999	COG3739	integral membrane protein
EM6_1000	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EM6_1001	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EM6_1002	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EM6_1004	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EM6_1004	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EM6_1005	COG0509	glycine decarboxylation via glycine cleavage system
EM6_1006	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EM6_1010	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EM6_1011	COG0328	RNA-DNA hybrid ribonuclease activity
EM6_1015	COG1702	phosphate starvation-inducible protein PhoH
EM6_1020	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EM6_1022	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EM6_1023	COG0745	RESPONSE REGULATOR receiver
EM6_1024	COG2205	protein histidine kinase activity
EM6_1027	COG0037	tRNA processing
EM6_1031	COG2885	chlorophyll binding
EM6_1032	COG0823	Involved in the tonB-independent uptake of proteins
EM6_1036	COG2255	four-way junction helicase activity
EM6_1037	COG0632	four-way junction helicase activity
EM6_1038	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EM6_1045	COG0488	(ABC) transporter
EM6_1046	COG3300	MHYT domain
EM6_1046	COG5001	Diguanylate cyclase
EM6_1050	COG2971	BadF BadG BcrA BcrD
EM6_1051	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EM6_1052	COG2885	chlorophyll binding
EM6_1057	COG0163	prenyltransferase activity
EM6_1066	COG0352	thiamine-phosphate diphosphorylase activity
EM6_1069	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EM6_1070	COG0483	inositol monophosphate 1-phosphatase activity
EM6_1071	COG1309	transcriptional regulator
EM6_1073	COG1132	(ABC) transporter
EM6_1074	COG0254	rRNA binding
EM6_1075	COG0387	Pfam Sodium calcium exchanger
EM6_1077	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EM6_1081	COG2171	N-acyltransferase activity
EM6_1083	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
EM6_1084	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EM6_1085	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EM6_1086	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EM6_1089	COG0489	protein tyrosine kinase activity
EM6_1090	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EM6_1093	COG0129	dihydroxy-acid dehydratase activity
EM6_1096	COG1012	belongs to the aldehyde dehydrogenase family
EM6_1105	COG0318	PFAM AMP-dependent synthetase and ligase
EM6_1108	COG4771	TonB-dependent receptor
EM6_1109	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EM6_1110	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EM6_1112	COG2066	Belongs to the glutaminase family
EM6_1114	COG1506	peptidase
EM6_1114	COG0823	Involved in the tonB-independent uptake of proteins
EM6_1117	COG1956	GAF domain-containing protein
EM6_1122	COG1238	metal cluster binding
EM6_1124	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
EM6_1127	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EM6_1132	COG0203	ribosomal protein L17
EM6_1134	COG0202	RNA polymerase activity
EM6_1135	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EM6_1136	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EM6_1137	COG0563	adenylate kinase activity
EM6_1138	COG0201	protein transport
EM6_1139	COG0200	Binds to the 23S rRNA
EM6_1140	COG1841	ribosomal large subunit assembly
EM6_1141	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EM6_1142	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EM6_1143	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EM6_1144	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EM6_1145	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EM6_1146	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EM6_1147	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EM6_1148	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EM6_1149	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EM6_1150	COG0255	Belongs to the universal ribosomal protein uL29 family
EM6_1151	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EM6_1152	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EM6_1153	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EM6_1154	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EM6_1155	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EM6_1156	COG0089	rRNA binding
EM6_1157	COG0088	Forms part of the polypeptide exit tunnel
EM6_1158	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EM6_1159	COG0051	transcription antitermination factor activity, RNA binding
EM6_1162	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EM6_1163	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EM6_1164	COG0049	tRNA binding
EM6_1165	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EM6_1167	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EM6_1169	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EM6_1170	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EM6_1173	COG0275	rRNA processing
EM6_1174	COG2001	Belongs to the MraZ family
EM6_1178	COG3023	N-Acetylmuramoyl-L-alanine amidase
EM6_1180	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EM6_1184	COG0006	proline dipeptidase activity
EM6_1188	COG1028	Short-chain dehydrogenase reductase Sdr
EM6_1192	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
EM6_1196	COG0463	Glycosyl transferase, family 2
EM6_1200	COG1132	(ABC) transporter
EM6_1202	COG2076	Multidrug Resistance protein
EM6_1204	COG0114	fumarate hydratase activity
EM6_1207	COG3842	ATPase activity
EM6_1208	COG1177	transmembrane transport
EM6_1209	COG1176	ABC-type spermidine putrescine transport system, permease component I
EM6_1211	COG0174	glutamine synthetase
EM6_1212	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EM6_1213	COG1012	belongs to the aldehyde dehydrogenase family
EM6_1214	COG1012	belongs to the aldehyde dehydrogenase family
EM6_1226	COG1522	sequence-specific DNA binding
EM6_1227	COG0686	Belongs to the AlaDH PNT family
EM6_1238	COG0443	Heat shock 70 kDa protein
EM6_1241	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EM6_1244	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EM6_1246	COG0107	imidazoleglycerol-phosphate synthase activity
EM6_1253	COG4948	Mandelate Racemase Muconate Lactonizing
EM6_1254	COG0385	Bile acid
EM6_1255	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EM6_1258	COG0442	prolyl-tRNA aminoacylation
EM6_1260	COG0625	glutathione transferase activity
EM6_1265	COG0738	Major facilitator superfamily
EM6_1267	COG1414	Transcriptional regulator
EM6_1270	COG2721	sulfolactate sulfo-lyase activity
EM6_1271	COG1028	Short-chain dehydrogenase reductase Sdr
EM6_1275	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EM6_1276	COG0732	type I restriction modification DNA specificity domain
EM6_1277	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EM6_1278	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EM6_1281	COG0477	Major facilitator Superfamily
EM6_1281	COG2814	Major facilitator Superfamily
EM6_1282	COG0129	dihydroxy-acid dehydratase activity
EM6_1283	COG3386	PFAM SMP-30 Gluconolaconase
EM6_1291	COG0505	Belongs to the CarA family
EM6_1292	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EM6_1294	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EM6_1297	COG1505	serine-type exopeptidase activity
EM6_1299	COG1414	Transcriptional regulator
EM6_1300	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EM6_1302	COG3250	beta-galactosidase activity
EM6_1306	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EM6_1310	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EM6_1312	COG1918	ferrous iron import across plasma membrane
EM6_1312	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EM6_1315	COG2252	PERMEase
EM6_1318	COG1472	Belongs to the glycosyl hydrolase 3 family
EM6_1319	COG1609	Transcriptional regulator
EM6_1320	COG0800	Aldolase
EM6_1321	COG0837	glucose binding
EM6_1323	COG0363	glucosamine-6-phosphate deaminase activity
EM6_1324	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EM6_1325	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EM6_1328	COG0308	aminopeptidase N
EM6_1330	COG2202	Pas domain
EM6_1330	COG2205	protein histidine kinase activity
EM6_1335	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EM6_1339	COG2205	protein histidine kinase activity
EM6_1343	COG1028	Short-chain dehydrogenase reductase Sdr
EM6_1345	COG5265	(ABC) transporter
EM6_1347	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EM6_1349	COG3657	addiction module killer protein
EM6_1350	COG2819	hydrolase of the alpha beta superfamily
EM6_1351	COG1082	Xylose isomerase domain protein TIM barrel
EM6_1353	COG1609	Transcriptional regulator
EM6_1355	COG1760	l-serine dehydratase
EM6_1362	COG1609	Transcriptional regulator
EM6_1368	COG5487	UPF0391 membrane protein
EM6_1370	COG1846	Transcriptional regulator
EM6_1376	COG5002	protein histidine kinase activity
EM6_1383	COG2186	Transcriptional regulator
EM6_1384	COG1301	dicarboxylic acid transport
EM6_1387	COG3655	Transcriptional regulator
EM6_1393	COG3088	subunit of a heme lyase
EM6_1394	COG1138	Cytochrome C-type biogenesis protein
EM6_1395	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
EM6_1398	COG2205	protein histidine kinase activity
EM6_1399	COG0745	RESPONSE REGULATOR receiver
EM6_1401	COG0484	heat shock protein binding
EM6_1415	COG4695	Portal protein
EM6_1419	COG2983	Belongs to the UPF0260 family
EM6_1427	COG1522	sequence-specific DNA binding
EM6_1430	COG1024	Enoyl-CoA hydratase
EM6_1433	COG1960	acyl-CoA dehydrogenase activity
EM6_1434	COG0439	Biotin carboxylase
EM6_1435	COG1024	Enoyl-CoA hydratase
EM6_1436	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EM6_1437	COG0583	DNA-binding transcription factor activity
EM6_1438	COG0028	Belongs to the TPP enzyme family
EM6_1439	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EM6_1440	COG1960	acyl-CoA dehydrogenase activity
EM6_1441	COG1012	belongs to the aldehyde dehydrogenase family
EM6_1442	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EM6_1449	COG1609	Transcriptional regulator
EM6_1461	COG1462	curli production assembly transport component CsgG
EM6_1463	COG0612	Peptidase, M16
EM6_1464	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EM6_1465	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EM6_1473	COG0717	Belongs to the dCTP deaminase family
EM6_1474	COG2967	ApaG domain
EM6_1475	COG0840	transmembrane signaling receptor activity
EM6_1479	COG0019	diaminopimelate decarboxylase activity
EM6_1481	COG0165	Argininosuccinate lyase
EM6_1482	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EM6_1483	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EM6_1486	COG2169	Transcriptional regulator
EM6_1486	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EM6_1487	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EM6_1487	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EM6_1489	COG2205	protein histidine kinase activity
EM6_1490	COG0745	RESPONSE REGULATOR receiver
EM6_1499	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EM6_1499	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EM6_1500	COG3549	Plasmid maintenance system killer
EM6_1505	COG1764	response to oxidative stress
EM6_1506	COG0121	glutamine amidotransferase
EM6_1510	COG1309	transcriptional regulator
EM6_1516	COG1250	3-hydroxyacyl-CoA dehydrogenase
EM6_1518	COG2311	Membrane
EM6_1519	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EM6_1519	COG1605	Chorismate mutase
EM6_1521	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EM6_1522	COG1199	ATP-dependent helicase activity
EM6_1524	COG0730	response to heat
EM6_1532	COG2224	Isocitrate lyase
EM6_1534	COG1396	sequence-specific DNA binding
EM6_1534	COG3800	Transcriptional regulator
EM6_1536	COG2186	Transcriptional regulator
EM6_1537	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EM6_1539	COG0523	cobalamin synthesis protein
EM6_1540	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EM6_1543	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EM6_1544	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EM6_1545	COG0799	negative regulation of ribosome biogenesis
EM6_1546	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EM6_1549	COG1671	Belongs to the UPF0178 family
EM6_1553	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EM6_1554	COG2885	chlorophyll binding
EM6_1556	COG1086	Polysaccharide biosynthesis protein
EM6_1557	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EM6_1558	COG2089	acid synthase
EM6_1561	COG1073	alpha beta
EM6_1563	COG0303	'Molybdopterin
EM6_1564	COG0521	Mo-molybdopterin cofactor biosynthetic process
EM6_1565	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EM6_1566	COG2272	Belongs to the type-B carboxylesterase lipase family
EM6_1569	COG0246	Mannitol dehydrogenase
EM6_1570	COG2721	sulfolactate sulfo-lyase activity
EM6_1571	COG1609	Transcriptional regulator
EM6_1572	COG1904	glucuronate isomerase
EM6_1576	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EM6_1578	COG4133	protoheme IX ABC transporter activity
EM6_1579	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EM6_1580	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EM6_1583	COG1605	Chorismate mutase
EM6_1583	COG0077	Prephenate dehydratase
EM6_1586	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EM6_1590	COG0793	Belongs to the peptidase S41A family
EM6_1599	COG4964	Belongs to the GSP D family
EM6_1605	COG2176	DNA-directed DNA polymerase activity
EM6_1609	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EM6_1610	COG0745	RESPONSE REGULATOR receiver
EM6_1612	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EM6_1617	COG0670	Belongs to the BI1 family
EM6_1621	COG3401	FG-GAP repeat protein
EM6_1622	COG2205	protein histidine kinase activity
EM6_1624	COG2124	cytochrome p450
EM6_1628	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EM6_1630	COG5507	3-demethylubiquinone-9 3-methyltransferase
EM6_1631	COG5507	3-demethylubiquinone-9 3-methyltransferase
EM6_1632	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EM6_1635	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EM6_1637	COG1309	transcriptional regulator
EM6_1640	COG1899	peptidyl-lysine modification to peptidyl-hypusine
EM6_1643	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EM6_1644	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
EM6_1645	COG3639	organic phosphonate transmembrane transporter activity
EM6_1646	COG1028	Short-chain dehydrogenase reductase Sdr
EM6_1650	COG2917	probably involved in intracellular septation
EM6_1651	COG0552	protein localization to endoplasmic reticulum
EM6_1652	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EM6_1653	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EM6_1655	COG0840	transmembrane signaling receptor activity
EM6_1656	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EM6_1657	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EM6_1658	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EM6_1659	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EM6_1660	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EM6_1662	COG1253	flavin adenine dinucleotide binding
EM6_1666	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EM6_1667	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EM6_1671	COG0508	dehydrogenase complex catalyzes the overall conversion of
EM6_1673	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EM6_1674	COG0045	succinate-CoA ligase (ADP-forming) activity
EM6_1675	COG2814	Major facilitator Superfamily
EM6_1687	COG1999	signal sequence binding
EM6_1689	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
EM6_1692	COG0640	Transcriptional regulator
EM6_1694	COG2205	protein histidine kinase activity
EM6_1696	COG0745	RESPONSE REGULATOR receiver
EM6_1700	COG0477	Major facilitator Superfamily
EM6_1704	COG1137	ATPase activity
EM6_1705	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EM6_1706	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EM6_1707	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EM6_1708	COG0427	acetyl-CoA hydrolase
EM6_1709	COG0071	Belongs to the small heat shock protein (HSP20) family
EM6_1711	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EM6_1712	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EM6_1713	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EM6_1717	COG2239	Acts as a magnesium transporter
EM6_1718	COG0633	Ferredoxin
EM6_1719	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EM6_1720	COG1053	succinate dehydrogenase
EM6_1722	COG2009	succinate dehydrogenase
EM6_1724	COG0039	L-malate dehydrogenase activity
EM6_1726	COG0436	Aminotransferase
EM6_1729	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EM6_1730	COG0228	four-way junction DNA binding
EM6_1731	COG0251	oxidation-reduction process
EM6_1732	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EM6_1733	COG4953	penicillin-binding protein 1C
EM6_1734	COG2373	Large extracellular alpha-helical protein
EM6_1735	COG0745	RESPONSE REGULATOR receiver
EM6_1739	COG0495	leucyl-tRNA aminoacylation
EM6_1742	COG1475	DNA binding
EM6_1743	COG1192	Involved in chromosome partitioning
EM6_1744	COG0357	Ribosomal RNA small subunit methyltransferase G
EM6_1746	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EM6_1748	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EM6_1750	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EM6_1751	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EM6_1752	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EM6_1753	COG0424	maF-like protein
EM6_1754	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EM6_1755	COG0237	dephospho-CoA kinase activity
EM6_1756	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EM6_1757	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EM6_1759	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
EM6_1761	COG0433	COG0433 Predicted ATPase
EM6_1764	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EM6_1770	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EM6_1771	COG1702	phosphate starvation-inducible protein PhoH
EM6_1772	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EM6_1773	COG1253	flavin adenine dinucleotide binding
EM6_1774	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EM6_1775	COG1396	sequence-specific DNA binding
EM6_1776	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EM6_1777	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EM6_1779	COG0779	Required for maturation of 30S ribosomal subunits
EM6_1783	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EM6_1783	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EM6_1787	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EM6_1788	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EM6_1789	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EM6_1790	COG1185	polyribonucleotide nucleotidyltransferase activity
EM6_1795	COG2133	pyrroloquinoline quinone binding
EM6_1796	COG0335	large ribosomal subunit rRNA binding
EM6_1797	COG0336	Belongs to the RNA methyltransferase TrmD family
EM6_1798	COG4771	TonB-dependent receptor
EM6_1800	COG1695	Transcriptional regulator
EM6_1805	COG1940	carbohydrate kinase activity
EM6_1805	COG1846	Transcriptional regulator
EM6_1808	COG0840	transmembrane signaling receptor activity
EM6_1810	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EM6_1811	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EM6_1812	COG1674	ftsk spoiiie
EM6_1813	COG3047	cAMP biosynthetic process
EM6_1815	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EM6_1818	COG1074	ATP-dependent DNA helicase activity
EM6_1820	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EM6_1821	COG3178	'Phosphotransferase
EM6_1822	COG0802	atpase or kinase
EM6_1827	COG2226	methyltransferase
EM6_1828	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EM6_1829	COG0840	transmembrane signaling receptor activity
EM6_1830	COG0598	Magnesium transport protein CorA
EM6_1831	COG5001	Diguanylate cyclase
EM6_1833	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EM6_1834	COG0756	dUTP diphosphatase activity
EM6_1836	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EM6_1837	COG0484	heat shock protein binding
EM6_1838	COG0443	Heat shock 70 kDa protein
EM6_1839	COG0412	Dienelactone hydrolase
EM6_1840	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EM6_1843	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EM6_1844	COG3655	Transcriptional regulator
EM6_1846	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EM6_1847	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EM6_1849	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EM6_1851	COG0189	ligase activity
EM6_1852	COG0606	chelatase, subunit chli
EM6_1853	COG5002	protein histidine kinase activity
EM6_1853	COG0784	Response regulator, receiver
EM6_1853	COG2205	protein histidine kinase activity
EM6_1854	COG2807	transmembrane transport
EM6_1855	COG0281	malic enzyme
EM6_1855	COG0280	phosphate acetyltransferase
EM6_1856	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EM6_1857	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EM6_1861	COG0728	peptidoglycan biosynthetic process
EM6_1862	COG0180	Tryptophanyl-tRNA synthetase
EM6_1866	COG0138	bifunctional purine biosynthesis protein purh
EM6_1868	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EM6_1869	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EM6_1869	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EM6_1870	COG0501	Belongs to the peptidase M48B family
EM6_1873	COG0284	orotidine-5'-phosphate decarboxylase activity
EM6_1874	COG2095	MarC family integral membrane protein
EM6_1875	COG4221	oxidoreductase activity
EM6_1876	COG1959	2 iron, 2 sulfur cluster binding
EM6_1877	COG3158	transport of potassium into the cell
EM6_1878	COG0137	argininosuccinate synthase activity
EM6_1879	COG0494	nUDIX hydrolase
EM6_1880	COG0187	DNA topoisomerase II activity
EM6_1881	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EM6_1884	COG0592	DNA-directed DNA polymerase activity
EM6_1885	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EM6_1887	COG0268	Binds directly to 16S ribosomal RNA
EM6_1888	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EM6_1890	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EM6_1891	COG0514	ATP-dependent DNA helicase (RecQ)
EM6_1892	COG2814	Major facilitator Superfamily
EM6_1893	COG5006	permease, DMT superfamily
EM6_1900	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EM6_1901	COG0539	negative regulation of cytoplasmic translation
EM6_1902	COG0776	regulation of translation
EM6_1903	COG1970	mechanosensitive ion channel activity
EM6_1905	COG0135	phosphoribosylanthranilate isomerase activity
EM6_1906	COG0133	tryptophan synthase activity
EM6_1907	COG0159	tryptophan synthase activity
EM6_1908	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EM6_1909	COG0285	dihydrofolate synthase activity
EM6_1910	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EM6_1914	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EM6_1916	COG0583	DNA-binding transcription factor activity
EM6_1917	COG0492	ferredoxin-NADP+ reductase activity
EM6_1921	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EM6_1923	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EM6_1924	COG5002	protein histidine kinase activity
EM6_1925	COG0704	Plays a role in the regulation of phosphate uptake
EM6_1926	COG0745	RESPONSE REGULATOR receiver
EM6_1928	COG0477	Major facilitator Superfamily
EM6_1929	COG3118	belongs to the thioredoxin family
EM6_1930	COG2835	tetraacyldisaccharide 4'-kinase activity
EM6_1932	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EM6_1934	COG0545	Peptidyl-prolyl cis-trans isomerase
EM6_1935	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EM6_1939	COG0288	reversible hydration of carbon dioxide
EM6_1941	COG1056	cytidyltransferase-related domain
EM6_1941	COG1051	belongs to the nudix hydrolase family
EM6_1942	COG1435	thymidine kinase activity
EM6_1946	COG2942	2-epimerase
EM6_1948	COG0175	sulfate reduction
EM6_1950	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EM6_1951	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EM6_1952	COG0517	IMP dehydrogenase activity
EM6_1952	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EM6_1958	COG0438	transferase activity, transferring glycosyl groups
EM6_1958	COG1216	Glycosyl transferase, family 2
EM6_1962	COG4372	Transposase
EM6_1971	COG4372	Transposase
EM6_1972	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
EM6_1973	COG1088	dTDP-glucose 4,6-dehydratase activity
EM6_1974	COG1091	dTDP-4-dehydrorhamnose reductase activity
EM6_1975	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EM6_1978	COG3754	Rhamnan synthesis protein F
EM6_1986	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EM6_1987	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
EM6_1988	COG0438	transferase activity, transferring glycosyl groups
EM6_1988	COG1216	Glycosyl transferase, family 2
EM6_1989	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EM6_1990	COG0339	signal peptide processing
EM6_1994	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EM6_1995	COG3932	Exopolysaccharide synthesis, ExoD
EM6_1996	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EM6_2002	COG4952	isomerase
EM6_2007	COG2755	lipolytic protein G-D-S-L family
EM6_2013	COG1083	cytidylyl-transferase
EM6_2016	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EM6_2018	COG1028	Short-chain dehydrogenase reductase Sdr
EM6_2022	COG1028	Short-chain dehydrogenase reductase Sdr
EM6_2024	COG4948	Mandelate Racemase Muconate Lactonizing
EM6_2025	COG1414	Transcriptional regulator
EM6_2026	COG1028	Short-chain dehydrogenase reductase Sdr
EM6_2028	COG1028	Short-chain dehydrogenase reductase Sdr
EM6_2031	COG1175	transmembrane transport
EM6_2032	COG0395	ABC-type sugar transport system, permease component
EM6_2035	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EM6_2042	COG0513	Belongs to the DEAD box helicase family
EM6_2045	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EM6_2046	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EM6_2047	COG0175	sulfate reduction
EM6_2049	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EM6_2051	COG1648	precorrin-2 dehydrogenase activity
EM6_2051	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EM6_2056	COG1012	belongs to the aldehyde dehydrogenase family
EM6_2059	COG0004	ammonium transporteR
EM6_2063	COG0166	Belongs to the GPI family
EM6_2065	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EM6_2069	COG1968	undecaprenyl-diphosphatase activity
EM6_2076	COG0438	transferase activity, transferring glycosyl groups
EM6_2077	COG1522	sequence-specific DNA binding
EM6_2081	COG0482	sulfurtransferase activity
EM6_2086	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EM6_2087	COG1749	Flagellar hook protein flgE
EM6_2089	COG1766	The M ring may be actively involved in energy transduction
EM6_2090	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EM6_2092	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EM6_2093	COG2204	response regulator
EM6_2095	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EM6_2099	COG1157	protein secretion by the type III secretion system
EM6_2101	COG3609	addiction module antidote protein, CC2985 family
EM6_2105	COG0745	RESPONSE REGULATOR receiver
EM6_2111	COG2201	protein-glutamate methylesterase activity
EM6_2114	COG2198	Histidine kinase
EM6_2114	COG0643	Histidine kinase
EM6_2119	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EM6_2122	COG2166	iron-sulfur cluster assembly
EM6_2123	COG2205	protein histidine kinase activity
EM6_2123	COG2202	Pas domain
EM6_2124	COG2205	protein histidine kinase activity
EM6_2128	COG1272	protein, Hemolysin III
EM6_2130	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EM6_2145	COG2205	protein histidine kinase activity
EM6_2146	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EM6_2147	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EM6_2148	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EM6_2151	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EM6_2152	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EM6_2155	COG1116	anion transmembrane transporter activity
EM6_2156	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EM6_2157	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EM6_2160	COG4771	TonB-dependent receptor
EM6_2162	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EM6_2163	COG3577	Aspartyl protease
EM6_2167	COG0840	transmembrane signaling receptor activity
EM6_2170	COG0556	nucleotide-excision repair
EM6_2175	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EM6_2177	COG0492	ferredoxin-NADP+ reductase activity
EM6_2179	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EM6_2183	COG2154	pterin-4-alpha-carbinolamine dehydratase
EM6_2184	COG3186	Phenylalanine-4-hydroxylase
EM6_2189	COG2205	protein histidine kinase activity
EM6_2191	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EM6_2198	COG0668	transmembrane transport
EM6_2203	COG0825	malonyl-CoA metabolic process
EM6_2204	COG4974	Belongs to the 'phage' integrase family
EM6_2205	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EM6_2206	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EM6_2209	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EM6_2210	COG1309	transcriptional regulator
EM6_2211	COG2321	neutral zinc metallopeptidase
EM6_2218	COG2010	Cytochrome c
EM6_2226	COG1309	transcriptional regulator
EM6_2227	COG0596	Alpha beta hydrolase
EM6_2227	COG2945	thiolester hydrolase activity
EM6_2228	COG4771	TonB-dependent receptor
EM6_2230	COG1028	Short-chain dehydrogenase reductase Sdr
EM6_2235	COG4677	pectinesterase activity
EM6_2238	COG2271	Major facilitator Superfamily
EM6_2239	COG0577	efflux transmembrane transporter activity
EM6_2240	COG1136	(ABC) transporter
EM6_2242	COG2204	response regulator
EM6_2243	COG3852	Histidine kinase
EM6_2245	COG1301	dicarboxylic acid transport
EM6_2247	COG4191	Histidine kinase
EM6_2248	COG2204	response regulator
EM6_2250	COG3250	beta-galactosidase activity
EM6_2252	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EM6_2253	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EM6_2258	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EM6_2260	COG3300	MHYT domain
EM6_2260	COG5001	Diguanylate cyclase
EM6_2264	COG4957	zinc ion binding
EM6_2274	COG1538	Outer membrane efflux protein
EM6_2275	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EM6_2276	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EM6_2278	COG0840	transmembrane signaling receptor activity
EM6_2279	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EM6_2280	COG0573	inorganic phosphate transmembrane transporter activity
EM6_2281	COG0581	inorganic phosphate transmembrane transporter activity
EM6_2282	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EM6_2284	COG3609	addiction module antidote protein, CC2985 family
EM6_2285	COG1304	FMN binding
EM6_2286	COG1028	Short-chain dehydrogenase reductase Sdr
EM6_2287	COG1609	Transcriptional regulator
EM6_2290	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EM6_2295	COG2866	Carboxypeptidase
EM6_2303	COG4771	TonB-dependent receptor
EM6_2305	COG1609	Transcriptional regulator
EM6_2307	COG2211	Major facilitator Superfamily
EM6_2310	COG1278	Cold shock
EM6_2314	COG3661	Belongs to the glycosyl hydrolase 67 family
EM6_2315	COG4948	Mandelate Racemase Muconate Lactonizing
EM6_2319	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EM6_2320	COG2011	ABC-type metal ion transport system permease component
EM6_2324	COG0475	glutathione-regulated potassium exporter activity
EM6_2326	COG0745	RESPONSE REGULATOR receiver
EM6_2330	COG4251	negative regulation of phosphorylation
EM6_2331	COG0784	Response regulator, receiver
EM6_2342	COG4206	TonB-dependent receptor
EM6_2344	COG0531	amino acid
EM6_2347	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EM6_2348	COG3254	rhamnose metabolic process
EM6_2349	COG1448	Aminotransferase
EM6_2352	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
EM6_2355	COG2271	Major facilitator Superfamily
EM6_2357	COG0784	Response regulator, receiver
EM6_2357	COG2205	protein histidine kinase activity
EM6_2366	COG0714	Associated with various cellular activities
EM6_2371	COG5002	protein histidine kinase activity
EM6_2371	COG5001	Diguanylate cyclase
EM6_2372	COG1309	transcriptional regulator
EM6_2374	COG5001	Diguanylate cyclase
EM6_2374	COG3300	MHYT domain
EM6_2375	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EM6_2378	COG2884	Cell division ATP-binding protein ftsE
EM6_2381	COG0204	Acyl-transferase
EM6_2386	COG0653	protein targeting
EM6_2387	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EM6_2388	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EM6_2392	COG0494	nUDIX hydrolase
EM6_2394	COG2226	methyltransferase
EM6_2395	COG1040	competence protein
EM6_2397	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EM6_2400	COG4232	protein-disulfide reductase activity
EM6_2403	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EM6_2408	COG0431	NADPH-dependent FMN reductase
EM6_2410	COG1573	uracil-dna glycosylase
EM6_2412	COG1187	pseudouridine synthase activity
EM6_2413	COG0519	Catalyzes the synthesis of GMP from XMP
EM6_2416	COG4771	TonB-dependent receptor
EM6_2418	COG1595	DNA-templated transcription, initiation
EM6_2419	COG0438	transferase activity, transferring glycosyl groups
EM6_2423	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EM6_2424	COG0484	heat shock protein binding
EM6_2425	COG0259	pyridoxamine-phosphate oxidase activity
EM6_2431	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EM6_2434	COG0196	riboflavin kinase activity
EM6_2436	COG0745	RESPONSE REGULATOR receiver
EM6_2440	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EM6_2441	COG2201	protein-glutamate methylesterase activity
EM6_2444	COG1570	exodeoxyribonuclease VII activity
EM6_2447	COG1754	DNA topoisomerase type I activity
EM6_2447	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EM6_2451	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EM6_2451	COG0758	DNA mediated transformation
EM6_2452	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EM6_2453	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EM6_2454	COG0540	Belongs to the ATCase OTCase family
EM6_2455	COG1064	alcohol dehydrogenase
EM6_2457	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EM6_2460	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EM6_2461	COG0154	amidase activity
EM6_2465	COG3152	Membrane
EM6_2468	COG0582	viral genome integration into host DNA
EM6_2481	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EM6_2482	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EM6_2482	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EM6_2490	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EM6_2491	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EM6_2493	COG2119	membrane
EM6_2498	COG2755	lipolytic protein G-D-S-L family
EM6_2499	COG0538	isocitrate dehydrogenase activity
EM6_2501	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
EM6_2510	COG3387	PFAM Glycoside hydrolase 15-related
EM6_2511	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
EM6_2512	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EM6_2514	COG0583	DNA-binding transcription factor activity
EM6_2519	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EM6_2523	COG2072	flavoprotein involved in K transport
EM6_2524	COG2351	hydroxyisourate hydrolase activity
EM6_2526	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EM6_2528	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EM6_2529	COG0402	S-adenosylhomocysteine deaminase activity
EM6_2531	COG0316	Belongs to the HesB IscA family
EM6_2532	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EM6_2533	COG0346	lactoylglutathione lyase activity
EM6_2536	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EM6_2538	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EM6_2539	COG1607	acyl-coa hydrolase
EM6_2546	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EM6_2550	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EM6_2552	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EM6_2552	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EM6_2557	COG0481	GTPase activity
EM6_2562	COG0673	inositol 2-dehydrogenase activity
EM6_2569	COG2755	lipolytic protein G-D-S-L family
EM6_2572	COG3250	beta-galactosidase activity
EM6_2574	COG2223	nitrite transmembrane transporter activity
EM6_2575	COG2201	protein-glutamate methylesterase activity
EM6_2577	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EM6_2579	COG0243	molybdopterin cofactor binding
EM6_2580	COG1116	anion transmembrane transporter activity
EM6_2581	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EM6_2582	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EM6_2587	COG2205	protein histidine kinase activity
EM6_2587	COG0784	Response regulator, receiver
EM6_2592	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EM6_2593	COG3250	beta-galactosidase activity
EM6_2594	COG1741	Belongs to the pirin family
EM6_2602	COG3104	oligopeptide transport
EM6_2604	COG0312	modulator of DNA gyrase
EM6_2606	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EM6_2607	COG0109	protoheme IX farnesyltransferase activity
EM6_2609	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
EM6_2612	COG3346	SURF1 family
EM6_2613	COG0612	Peptidase, M16
EM6_2614	COG0584	glycerophosphoryl diester phosphodiesterase
EM6_2615	COG1678	Uncharacterized ACR, COG1678
EM6_2617	COG1960	acyl-CoA dehydrogenase activity
EM6_2619	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
EM6_2624	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EM6_2625	COG0602	queuosine metabolic process
EM6_2626	COG0248	Ppx GppA phosphatase
EM6_2630	COG0343	queuine tRNA-ribosyltransferase activity
EM6_2632	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EM6_2633	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EM6_2635	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EM6_2636	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EM6_2646	COG0519	Catalyzes the synthesis of GMP from XMP
EM6_2646	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EM6_2647	COG0582	viral genome integration into host DNA
EM6_2653	COG4206	TonB-dependent receptor
EM6_2656	COG0431	NADPH-dependent FMN reductase
EM6_2658	COG1393	Belongs to the ArsC family
EM6_2660	COG1595	DNA-templated transcription, initiation
EM6_2662	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EM6_2665	COG1160	GTP binding
EM6_2670	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EM6_2673	COG0305	Participates in initiation and elongation during chromosome replication
EM6_2680	COG2226	methyltransferase
EM6_2681	COG1301	dicarboxylic acid transport
EM6_2682	COG0544	peptidyl-prolyl cis-trans isomerase activity
EM6_2684	COG0740	serine-type endopeptidase activity
EM6_2685	COG0560	Phosphoserine phosphatase
EM6_2686	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EM6_2690	COG0501	Belongs to the peptidase M48B family
EM6_2691	COG1530	ribonuclease E activity
EM6_2694	COG3474	cytochrome
EM6_2698	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EM6_2699	COG0776	regulation of translation
EM6_2706	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EM6_2707	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EM6_2708	COG0649	NAD binding
EM6_2711	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EM6_2712	COG2314	TM2 domain
EM6_2714	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EM6_2715	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EM6_2717	COG0713	ATP synthesis coupled electron transport
EM6_2720	COG1007	ATP synthesis coupled electron transport
EM6_2722	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EM6_2724	COG3243	poly(R)-hydroxyalkanoic acid synthase
EM6_2726	COG1494	fructose-1,6-bisphosphatase
EM6_2727	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EM6_2727	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EM6_2730	COG1278	Cold shock
EM6_2734	COG3034	peptidoglycan biosynthetic process
EM6_2738	COG1612	heme a metabolic process
EM6_2740	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EM6_2741	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EM6_2742	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EM6_2745	COG0442	prolyl-tRNA aminoacylation
EM6_2747	COG1136	(ABC) transporter
EM6_2749	COG0587	DNA-directed DNA polymerase activity
EM6_2750	COG0052	Belongs to the universal ribosomal protein uS2 family
EM6_2751	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EM6_2752	COG0528	UMP kinase activity
EM6_2753	COG0233	cytoplasmic translational termination
EM6_2754	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EM6_2755	COG4589	Belongs to the CDS family
EM6_2756	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EM6_2757	COG0750	zinc metalloprotease
EM6_2758	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EM6_2760	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EM6_2761	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EM6_2762	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EM6_2764	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EM6_2765	COG0372	Belongs to the citrate synthase family
EM6_2766	COG0658	competence protein
EM6_2766	COG2333	competence protein COMEC
EM6_2767	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EM6_2768	COG0134	indole-3-glycerol-phosphate synthase activity
EM6_2769	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EM6_2772	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EM6_2773	COG1923	regulation of RNA biosynthetic process
EM6_2774	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EM6_2775	COG2204	response regulator
EM6_2776	COG5000	phosphorelay sensor kinase activity
EM6_2778	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EM6_2778	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EM6_2779	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EM6_2779	COG0321	lipoyl(octanoyl) transferase activity
EM6_2780	COG0084	hydrolase, TatD family'
EM6_2781	COG0470	DNA polymerase III
EM6_2782	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EM6_2790	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EM6_2791	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EM6_2792	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EM6_2795	COG0463	Glycosyl transferase, family 2
EM6_2796	COG0415	Belongs to the DNA photolyase family
EM6_2797	COG2897	thiosulfate sulfurtransferase activity
EM6_2798	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EM6_2801	COG0251	oxidation-reduction process
EM6_2802	COG0504	CTP synthase activity
EM6_2804	COG0149	triose-phosphate isomerase activity
EM6_2806	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EM6_2808	COG4651	solute:proton antiporter activity
EM6_2808	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EM6_2810	COG3956	TIGRFAM MazG family protein
EM6_2811	COG0823	Involved in the tonB-independent uptake of proteins
EM6_2814	COG1121	(ABC) transporter
EM6_2815	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EM6_2816	COG1546	Belongs to the CinA family
EM6_2816	COG1058	Belongs to the CinA family
EM6_2818	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EM6_2820	COG0204	Acyl-transferase
EM6_2820	COG0318	PFAM AMP-dependent synthetase and ligase
EM6_2824	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EM6_2825	COG0508	dehydrogenase complex catalyzes the overall conversion of
EM6_2826	COG0022	dehydrogenase e1 component
EM6_2826	COG0508	dehydrogenase complex catalyzes the overall conversion of
EM6_2827	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EM6_2828	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EM6_2829	COG0148	phosphopyruvate hydratase activity
EM6_2830	COG0546	phosphoglycolate phosphatase activity
EM6_2831	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EM6_2836	COG0776	regulation of translation
EM6_2837	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EM6_2838	COG0416	fatty acid biosynthetic process
EM6_2843	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EM6_2845	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EM6_2846	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EM6_2847	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EM6_2848	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EM6_2848	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EM6_2851	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EM6_2853	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EM6_2856	COG0156	8-amino-7-oxononanoate synthase activity
EM6_2858	COG0113	porphobilinogen synthase activity
EM6_2860	COG2084	Dehydrogenase
EM6_2861	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EM6_2862	COG1360	Flagellar Motor Protein
EM6_2863	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
EM6_2864	COG3932	Exopolysaccharide synthesis, ExoD
EM6_2865	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EM6_2868	COG1381	Involved in DNA repair and RecF pathway recombination
EM6_2869	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EM6_2870	COG0571	ribonuclease III activity
EM6_2871	COG0681	Belongs to the peptidase S26 family
EM6_2872	COG0736	holo-[acyl-carrier-protein] synthase activity
EM6_2873	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EM6_2874	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EM6_2879	COG1758	RNA polymerase activity
EM6_2881	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EM6_2883	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EM6_2884	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EM6_2885	COG0741	lytic transglycosylase activity
EM6_2886	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EM6_2890	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EM6_2890	COG0116	Belongs to the methyltransferase superfamily
EM6_2891	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EM6_2895	COG1643	Atp-dependent helicase
EM6_2896	COG0531	amino acid
EM6_2897	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EM6_2899	COG2081	HI0933 family
EM6_2900	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EM6_2901	COG0085	RNA polymerase activity
EM6_2904	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EM6_2905	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EM6_2907	COG0194	GDP metabolic process
EM6_2908	COG1561	YicC-like family, N-terminal region
EM6_2909	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EM6_2910	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EM6_2911	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EM6_2913	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EM6_2914	COG1073	alpha beta
EM6_2915	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EM6_2916	COG0360	Binds together with S18 to 16S ribosomal RNA
EM6_2918	COG0359	binds to the 23S rRNA
EM6_2920	COG0347	Belongs to the P(II) protein family
EM6_2921	COG0174	glutamine synthetase
EM6_2922	COG0004	ammonium transporteR
EM6_2925	COG0187	DNA topoisomerase II activity
EM6_2926	COG0513	Belongs to the DEAD box helicase family
EM6_2927	COG3706	GGDEF domain
EM6_2931	COG0316	Belongs to the HesB IscA family
EM6_2932	COG2151	metal-sulfur cluster biosynthetic enzyme
EM6_2933	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EM6_2934	COG0719	Fe-S assembly protein
EM6_2935	COG0396	ATPase activity
EM6_2937	COG0719	Fe-S assembly protein
EM6_2938	COG1104	cysteine desulfurase activity
EM6_2939	COG1959	2 iron, 2 sulfur cluster binding
EM6_2940	COG2945	thiolester hydrolase activity
EM6_2941	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EM6_2942	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EM6_2944	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EM6_2945	COG0739	heme binding
EM6_2949	COG0222	ribosome binding
EM6_2950	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EM6_2951	COG4977	sequence-specific DNA binding
EM6_2954	COG3609	addiction module antidote protein, CC2985 family
EM6_2955	COG0081	regulation of translation
EM6_2956	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EM6_2958	COG0250	Participates in transcription elongation, termination and antitermination
EM6_2964	COG2832	Protein of unknown function (DUF454)
EM6_2965	COG3152	Membrane
EM6_2966	COG0412	Dienelactone hydrolase
EM6_2967	COG0861	Integral membrane protein TerC family
EM6_2971	COG3152	Membrane
EM6_2972	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EM6_2976	COG2022	thiamine diphosphate biosynthetic process
EM6_2978	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EM6_2979	COG0511	ligase activity, forming carbon-carbon bonds
EM6_2980	COG0439	Biotin carboxylase
EM6_2983	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EM6_2986	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EM6_2989	COG0248	Ppx GppA phosphatase
EM6_2991	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EM6_2992	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EM6_2993	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EM6_2994	COG0105	UTP biosynthetic process
EM6_2995	COG0488	(ABC) transporter
EM6_2998	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EM6_3002	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EM6_3003	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EM6_3006	COG0235	Class ii aldolase
EM6_3008	COG0330	HflC and HflK could
EM6_3010	COG0277	FAD linked oxidase domain protein
EM6_3011	COG0745	RESPONSE REGULATOR receiver
EM6_3012	COG3022	response to hydroperoxide
EM6_3013	COG0009	L-threonylcarbamoyladenylate synthase
EM6_3014	COG3038	cytochrome b561
EM6_3015	COG1960	acyl-CoA dehydrogenase activity
EM6_3020	COG1686	Belongs to the peptidase S11 family
EM6_3022	COG1192	Involved in chromosome partitioning
EM6_3023	COG0024	Methionine aminopeptidase
EM6_3024	COG2003	Belongs to the UPF0758 family
EM6_3025	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
EM6_3026	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EM6_3028	COG3250	beta-galactosidase activity
EM6_3028	COG5297	Belongs to the glycosyl hydrolase family 6
EM6_3029	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EM6_3032	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EM6_3033	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EM6_3034	COG0047	phosphoribosylformylglycinamidine synthase activity
EM6_3038	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EM6_3042	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EM6_3043	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EM6_3044	COG1253	flavin adenine dinucleotide binding
EM6_3048	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EM6_3049	COG0840	transmembrane signaling receptor activity
EM6_3050	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EM6_3051	COG2032	superoxide dismutase activity
EM6_3052	COG0564	pseudouridine synthase activity
EM6_3058	COG0386	Belongs to the glutathione peroxidase family
EM6_3059	COG1396	sequence-specific DNA binding
EM6_3061	COG1741	Belongs to the pirin family
EM6_3064	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EM6_3065	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EM6_3066	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EM6_3067	COG0629	single-stranded DNA binding
EM6_3070	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EM6_3073	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EM6_3074	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EM6_3075	COG5442	Flagellar protein FlaF
EM6_3076	COG5443	negative regulation of bacterial-type flagellum assembly
EM6_3077	COG0457	Tetratricopeptide repeat
EM6_3077	COG0859	PFAM glycosyl transferase family 9
EM6_3079	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
EM6_3081	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EM6_3081	COG3743	rRNA binding
EM6_3083	COG0574	Belongs to the PEP-utilizing enzyme family
EM6_3083	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EM6_3084	COG0751	glycine-tRNA ligase activity
EM6_3085	COG0752	glycyl-tRNA synthetase alpha subunit
EM6_3088	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EM6_3094	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EM6_3100	COG0525	valine-tRNA ligase activity
EM6_3105	COG0840	transmembrane signaling receptor activity
EM6_3107	COG0745	RESPONSE REGULATOR receiver
EM6_3107	COG3706	GGDEF domain
EM6_3108	COG0784	Response regulator, receiver
EM6_3112	COG0546	phosphoglycolate phosphatase activity
EM6_3114	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EM6_3115	COG0537	adenosine 5'-monophosphoramidase activity
EM6_3116	COG0406	alpha-ribazole phosphatase activity
EM6_3120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EM6_3134	COG1668	transmembrane transport
EM6_3135	COG4152	abc transporter atp-binding protein
EM6_3136	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EM6_3139	COG4585	Histidine kinase
EM6_3140	COG2197	response regulator
EM6_3143	COG4771	TonB-dependent receptor
EM6_3146	COG1297	OPT oligopeptide transporter protein
EM6_3147	COG4771	TonB-dependent receptor
EM6_3152	COG3590	peptidase
EM6_3155	COG0124	histidyl-tRNA synthetase
EM6_3157	COG2890	protein-(glutamine-N5) methyltransferase activity
EM6_3158	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EM6_3159	COG0527	aspartate kinase activity
EM6_3160	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EM6_3164	COG3300	MHYT domain
EM6_3164	COG5001	Diguanylate cyclase
EM6_3165	COG0312	modulator of DNA gyrase
EM6_3166	COG0483	inositol monophosphate 1-phosphatase activity
EM6_3170	COG1132	(ABC) transporter
EM6_3172	COG1519	Transferase
EM6_3173	COG1663	tetraacyldisaccharide 4'-kinase activity
EM6_3175	COG0151	Belongs to the GarS family
EM6_3179	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EM6_3180	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EM6_3182	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EM6_3184	COG0742	ribosomal rna small subunit methyltransferase
EM6_3185	COG1187	pseudouridine synthase activity
EM6_3194	COG3250	beta-galactosidase activity
EM6_3207	COG3250	beta-galactosidase activity
EM6_3208	COG2971	BadF BadG BcrA BcrD
EM6_3212	COG2186	Transcriptional regulator
EM6_3213	COG2186	Transcriptional regulator
EM6_3216	COG2801	Transposase and inactivated derivatives
EM6_3217	COG1737	Transcriptional regulator
EM6_3219	COG3540	Alkaline phosphatase
EM6_3221	COG1028	Short-chain dehydrogenase reductase Sdr
EM6_3222	COG4948	Mandelate Racemase Muconate Lactonizing
EM6_3223	COG2186	Transcriptional regulator
EM6_3224	COG2814	Major facilitator Superfamily
EM6_3225	COG0754	glutathionylspermidine amidase activity
EM6_3234	COG3220	belongs to the UPF0276 family
EM6_3237	COG3220	belongs to the UPF0276 family
EM6_3239	COG1595	DNA-templated transcription, initiation
EM6_3244	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
EM6_3245	COG0415	Belongs to the DNA photolyase family
EM6_3247	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EM6_3271	COG0519	Catalyzes the synthesis of GMP from XMP
EM6_3271	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EM6_3273	COG4771	TonB-dependent receptor
EM6_3281	COG1396	sequence-specific DNA binding
EM6_3289	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EM6_3295	COG1396	sequence-specific DNA binding
EM6_3302	COG4962	Type ii secretion system protein e
EM6_3305	COG3451	type IV secretory pathway VirB4
EM6_3307	COG3846	protein secretion by the type IV secretion system
EM6_3310	COG2948	multi-organism process
EM6_3314	COG0840	transmembrane signaling receptor activity
EM6_3315	COG0667	Aldo Keto reductase
EM6_3317	COG2801	Transposase and inactivated derivatives
EM6_3321	COG1064	alcohol dehydrogenase
EM6_3326	COG1028	Short-chain dehydrogenase reductase Sdr
EM6_3328	COG0183	Belongs to the thiolase family
EM6_3329	COG0667	Aldo Keto reductase
EM6_3331	COG0667	Aldo Keto reductase
EM6_3332	COG1028	Short-chain dehydrogenase reductase Sdr
EM6_3335	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
EM6_3336	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EM6_3343	COG0776	regulation of translation
EM6_3344	COG4957	zinc ion binding
EM6_3349	COG2197	response regulator
EM6_3351	COG2204	response regulator
EM6_3362	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
EM6_3364	COG2271	Major facilitator Superfamily
EM6_3369	COG1414	Transcriptional regulator
EM6_3371	COG0179	Fumarylacetoacetate (FAA) hydrolase
EM6_3374	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EM6_3377	COG0840	transmembrane signaling receptor activity
EM6_3378	COG1192	Involved in chromosome partitioning
EM6_3379	COG1475	DNA binding
EM6_3381	COG3940	Belongs to the glycosyl hydrolase 43 family
EM6_3383	COG3718	enzyme involved in inositol metabolism
EM6_3385	COG3962	Belongs to the TPP enzyme family
EM6_3386	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EM6_3388	COG0673	inositol 2-dehydrogenase activity
EM6_3389	COG3537	Alpha-1,2-mannosidase
EM6_3390	COG1172	Belongs to the binding-protein-dependent transport system permease family
EM6_3391	COG1129	ABC transporter
EM6_3392	COG1879	ABC-type sugar transport system periplasmic component
EM6_3394	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EM6_3395	COG1845	cytochrome c oxidase, subunit III
EM6_3396	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EM6_3397	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor