locus-tag	class	description
ATHSA_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ATHSA_0002	COG1132	(ABC) transporter
ATHSA_0003	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ATHSA_0007	COG1609	Transcriptional regulator
ATHSA_0008	COG0714	Associated with various cellular activities
ATHSA_0012	COG1131	(ABC) transporter
ATHSA_0014	COG1136	(ABC) transporter
ATHSA_0014	COG0577	efflux transmembrane transporter activity
ATHSA_0015	COG1136	(ABC) transporter
ATHSA_0020	COG1923	regulation of RNA biosynthetic process
ATHSA_0023	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ATHSA_0024	COG0095	Lipoate-protein ligase
ATHSA_0025	COG0357	Ribosomal RNA small subunit methyltransferase G
ATHSA_0026	COG0395	ABC-type sugar transport system, permease component
ATHSA_0028	COG0513	Belongs to the DEAD box helicase family
ATHSA_0030	COG0575	Belongs to the CDS family
ATHSA_0032	COG0233	cytoplasmic translational termination
ATHSA_0033	COG0528	UMP kinase activity
ATHSA_0034	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ATHSA_0038	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ATHSA_0042	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ATHSA_0043	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ATHSA_0047	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ATHSA_0048	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ATHSA_0050	COG0572	uridine kinase
ATHSA_0052	COG4786	Flagellar basal body rod
ATHSA_0053	COG4786	Flagellar basal body rod
ATHSA_0055	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ATHSA_0056	COG1706	bacterial-type flagellum-dependent cell motility
ATHSA_0059	COG1271	oxidase subunit
ATHSA_0060	COG1294	oxidase, subunit
ATHSA_0063	COG0673	inositol 2-dehydrogenase activity
ATHSA_0066	COG1523	belongs to the glycosyl hydrolase 13 family
ATHSA_0068	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ATHSA_0071	COG0203	ribosomal protein L17
ATHSA_0072	COG0202	RNA polymerase activity
ATHSA_0073	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ATHSA_0074	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ATHSA_0075	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ATHSA_0076	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ATHSA_0077	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ATHSA_0079	COG0563	adenylate kinase activity
ATHSA_0080	COG0201	protein transport
ATHSA_0081	COG0200	Binds to the 23S rRNA
ATHSA_0082	COG1841	ribosomal large subunit assembly
ATHSA_0083	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ATHSA_0084	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ATHSA_0085	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ATHSA_0086	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ATHSA_0088	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ATHSA_0089	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ATHSA_0090	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ATHSA_0092	COG0255	Belongs to the universal ribosomal protein uL29 family
ATHSA_0093	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ATHSA_0094	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ATHSA_0095	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ATHSA_0096	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ATHSA_0097	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ATHSA_0098	COG0089	rRNA binding
ATHSA_0099	COG0088	Forms part of the polypeptide exit tunnel
ATHSA_0100	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ATHSA_0101	COG0051	transcription antitermination factor activity, RNA binding
ATHSA_0102	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ATHSA_0103	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ATHSA_0104	COG0049	tRNA binding
ATHSA_0105	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ATHSA_0106	COG0438	transferase activity, transferring glycosyl groups
ATHSA_0109	COG2201	protein-glutamate methylesterase activity
ATHSA_0112	COG1013	pyruvate-flavodoxin oxidoreductase activity
ATHSA_0113	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ATHSA_0114	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ATHSA_0115	COG0802	atpase or kinase
ATHSA_0116	COG1073	alpha beta
ATHSA_0117	COG1070	Carbohydrate kinase
ATHSA_0124	COG1702	phosphate starvation-inducible protein PhoH
ATHSA_0125	COG1480	7TM receptor with intracellular HD hydrolase
ATHSA_0126	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ATHSA_0131	COG0204	Acyl-transferase
ATHSA_0132	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ATHSA_0133	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ATHSA_0134	COG1396	sequence-specific DNA binding
ATHSA_0137	COG1987	bacterial-type flagellum assembly
ATHSA_0138	COG1684	flagellar biosynthetic protein fliR
ATHSA_0140	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ATHSA_0141	COG1419	protein localization to endoplasmic reticulum
ATHSA_0142	COG0455	bacterial-type flagellum organization
ATHSA_0143	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
ATHSA_0144	COG1776	CheC inhibitor of MCP methylation
ATHSA_0145	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ATHSA_0147	COG1191	sigma factor activity
ATHSA_0149	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ATHSA_0151	COG0504	CTP synthase activity
ATHSA_0152	COG0647	UMP catabolic process
ATHSA_0153	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ATHSA_0154	COG0800	Aldolase
ATHSA_0155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ATHSA_0156	COG1312	Catalyzes the dehydration of D-mannonate
ATHSA_0157	COG1028	Short-chain dehydrogenase reductase Sdr
ATHSA_0165	COG1501	Belongs to the glycosyl hydrolase 31 family
ATHSA_0166	COG1472	Belongs to the glycosyl hydrolase 3 family
ATHSA_0168	COG1940	carbohydrate kinase activity
ATHSA_0169	COG1070	Carbohydrate kinase
ATHSA_0170	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
ATHSA_0171	COG0735	belongs to the Fur family
ATHSA_0172	COG0426	domain, Protein
ATHSA_0173	COG1528	Iron-storage protein
ATHSA_0174	COG2033	superoxide reductase activity
ATHSA_0179	COG1595	DNA-templated transcription, initiation
ATHSA_0180	COG0268	Binds directly to 16S ribosomal RNA
ATHSA_0181	COG0737	Belongs to the 5'-nucleotidase family
ATHSA_0182	COG2030	dehydratase
ATHSA_0183	COG0180	Tryptophanyl-tRNA synthetase
ATHSA_0184	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ATHSA_0185	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ATHSA_0186	COG1187	pseudouridine synthase activity
ATHSA_0191	COG5002	protein histidine kinase activity
ATHSA_0192	COG1639	'signal transduction protein
ATHSA_0193	COG0860	N-Acetylmuramoyl-L-alanine amidase
ATHSA_0194	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ATHSA_0195	COG0284	orotidine-5'-phosphate decarboxylase activity
ATHSA_0196	COG0167	dihydroorotate dehydrogenase activity
ATHSA_0199	COG0540	Belongs to the ATCase OTCase family
ATHSA_0201	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ATHSA_0202	COG0746	molybdenum cofactor guanylyltransferase activity
ATHSA_0203	COG3383	formate dehydrogenase (NAD+) activity
ATHSA_0204	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ATHSA_0205	COG3404	Formiminotransferase-cyclodeaminase
ATHSA_0206	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ATHSA_0220	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ATHSA_0223	COG0601	transmembrane transport
ATHSA_0224	COG4608	Belongs to the ABC transporter superfamily
ATHSA_0225	COG4166	transmembrane transport
ATHSA_0226	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ATHSA_0227	COG0402	S-adenosylhomocysteine deaminase activity
ATHSA_0228	COG1228	amidohydrolase
ATHSA_0229	COG0747	negative chemotaxis
ATHSA_0230	COG0531	amino acid
ATHSA_0231	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ATHSA_0232	COG0747	negative chemotaxis
ATHSA_0234	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ATHSA_0235	COG0277	FAD linked oxidase domain protein
ATHSA_0237	COG2086	electron transfer activity
ATHSA_0238	COG1012	belongs to the aldehyde dehydrogenase family
ATHSA_0239	COG3875	lactate racemase activity
ATHSA_0240	COG1070	Carbohydrate kinase
ATHSA_0241	COG4952	isomerase
ATHSA_0244	COG1879	ABC-type sugar transport system periplasmic component
ATHSA_0245	COG1172	Belongs to the binding-protein-dependent transport system permease family
ATHSA_0246	COG1172	Belongs to the binding-protein-dependent transport system permease family
ATHSA_0247	COG1129	ABC transporter
ATHSA_0252	COG1349	DNA-binding transcription factor activity
ATHSA_0253	COG1830	Aldolase
ATHSA_0255	COG3340	Belongs to the peptidase S51 family
ATHSA_0256	COG0768	penicillin binding
ATHSA_0257	COG2379	hydroxypyruvate reductase
ATHSA_0260	COG1511	domain protein
ATHSA_0260	COG3264	Mechanosensitive ion channel
ATHSA_0261	COG4946	Tricorn protease homolog
ATHSA_0261	COG0793	Belongs to the peptidase S41A family
ATHSA_0266	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ATHSA_0267	COG0792	nuclease activity
ATHSA_0268	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ATHSA_0270	COG3386	PFAM SMP-30 Gluconolaconase
ATHSA_0272	COG4166	transmembrane transport
ATHSA_0273	COG1609	Transcriptional regulator
ATHSA_0274	COG0656	L-ascorbic acid biosynthetic process
ATHSA_0275	COG0667	Aldo Keto reductase
ATHSA_0276	COG0667	Aldo Keto reductase
ATHSA_0277	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
ATHSA_0278	COG0667	Aldo Keto reductase
ATHSA_0280	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ATHSA_0281	COG0750	zinc metalloprotease
ATHSA_0284	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ATHSA_0284	COG2080	2 iron, 2 sulfur cluster binding
ATHSA_0287	COG0735	belongs to the Fur family
ATHSA_0288	COG0436	Aminotransferase
ATHSA_0292	COG0640	Transcriptional regulator
ATHSA_0293	COG0798	PFAM Bile acid sodium symporter
ATHSA_0294	COG0393	Putative heavy-metal-binding
ATHSA_0296	COG1131	(ABC) transporter
ATHSA_0297	COG1725	Transcriptional regulator
ATHSA_0298	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ATHSA_0300	COG0732	type I restriction modification DNA specificity domain
ATHSA_0301	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ATHSA_0309	COG0673	inositol 2-dehydrogenase activity
ATHSA_0310	COG0588	phosphoglycerate mutase activity
ATHSA_0314	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ATHSA_0315	COG4989	oxidoreductase activity
ATHSA_0316	COG2814	Major facilitator Superfamily
ATHSA_0317	COG1584	GPR1 FUN34 yaaH family protein
ATHSA_0318	COG0531	amino acid
ATHSA_0320	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ATHSA_0321	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ATHSA_0322	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ATHSA_0324	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ATHSA_0325	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ATHSA_0326	COG0673	inositol 2-dehydrogenase activity
ATHSA_0327	COG1428	Deoxynucleoside kinase
ATHSA_0332	COG0751	glycine-tRNA ligase activity
ATHSA_0333	COG0752	glycyl-tRNA synthetase alpha subunit
ATHSA_0334	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ATHSA_0335	COG0745	RESPONSE REGULATOR receiver
ATHSA_0336	COG5002	protein histidine kinase activity
ATHSA_0338	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ATHSA_0339	COG2359	stage V sporulation protein S
ATHSA_0341	COG3872	metal-dependent enzyme
ATHSA_0342	COG2814	Major facilitator Superfamily
ATHSA_0354	COG1272	protein, Hemolysin III
ATHSA_0355	COG1609	Transcriptional regulator
ATHSA_0360	COG1175	transmembrane transport
ATHSA_0368	COG0395	ABC-type sugar transport system, permease component
ATHSA_0369	COG1175	transmembrane transport
ATHSA_0370	COG2182	Extracellular solute-binding protein
ATHSA_0375	COG1396	sequence-specific DNA binding
ATHSA_0380	COG0562	UDP-galactopyranose mutase
ATHSA_0382	COG1418	mRNA catabolic process
ATHSA_0386	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ATHSA_0389	COG0758	DNA mediated transformation
ATHSA_0393	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ATHSA_0397	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ATHSA_0398	COG1349	DNA-binding transcription factor activity
ATHSA_0399	COG0434	BtpA family
ATHSA_0400	COG1070	Carbohydrate kinase
ATHSA_0401	COG1028	Short-chain dehydrogenase reductase Sdr
ATHSA_0403	COG4143	(ABC) transporter
ATHSA_0406	COG1176	ABC-type spermidine putrescine transport system, permease component I
ATHSA_0408	COG3842	ATPase activity
ATHSA_0409	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ATHSA_0409	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ATHSA_0413	COG0728	peptidoglycan biosynthetic process
ATHSA_0414	COG0148	phosphopyruvate hydratase activity
ATHSA_0415	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ATHSA_0416	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ATHSA_0417	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ATHSA_0418	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ATHSA_0419	COG0772	Belongs to the SEDS family
ATHSA_0420	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ATHSA_0421	COG0840	transmembrane signaling receptor activity
ATHSA_0422	COG1739	Uncharacterized protein family UPF0029
ATHSA_0423	COG1323	Belongs to the UPF0348 family
ATHSA_0425	COG1254	Belongs to the acylphosphatase family
ATHSA_0426	COG0561	phosphatase activity
ATHSA_0427	COG1776	CheC inhibitor of MCP methylation
ATHSA_0427	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ATHSA_0428	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ATHSA_0433	COG1749	Flagellar hook protein flgE
ATHSA_0434	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ATHSA_0438	COG2814	Major facilitator Superfamily
ATHSA_0439	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ATHSA_0440	COG1846	Transcriptional regulator
ATHSA_0441	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ATHSA_0442	COG0166	Belongs to the GPI family
ATHSA_0443	COG4656	Part of a membrane complex involved in electron transport
ATHSA_0444	COG4658	electron transport chain
ATHSA_0446	COG4660	Part of a membrane complex involved in electron transport
ATHSA_0447	COG4657	Part of a membrane complex involved in electron transport
ATHSA_0448	COG1245	4Fe-4S binding domain
ATHSA_0448	COG2878	Part of a membrane complex involved in electron transport
ATHSA_0452	COG0012	GTP binding
ATHSA_0453	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ATHSA_0454	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ATHSA_0456	COG3437	response regulator, receiver
ATHSA_0456	COG0784	Response regulator, receiver
ATHSA_0458	COG1342	Belongs to the UPF0251 family
ATHSA_0459	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ATHSA_0459	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ATHSA_0460	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ATHSA_0462	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
ATHSA_0463	COG0653	protein targeting
ATHSA_0464	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ATHSA_0467	COG1744	ABC transporter substrate-binding protein PnrA-like
ATHSA_0468	COG0584	glycerophosphoryl diester phosphodiesterase
ATHSA_0473	COG1830	Aldolase
ATHSA_0477	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ATHSA_0478	COG0720	synthase
ATHSA_0483	COG0542	response to heat
ATHSA_0484	COG0071	Belongs to the small heat shock protein (HSP20) family
ATHSA_0485	COG0443	Heat shock 70 kDa protein
ATHSA_0488	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ATHSA_0489	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ATHSA_0490	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ATHSA_0491	COG1561	YicC-like family, N-terminal region
ATHSA_0492	COG2052	Domain of unknown function (DUF370)
ATHSA_0493	COG0194	GDP metabolic process
ATHSA_0494	COG1758	RNA polymerase activity
ATHSA_0495	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ATHSA_0496	COG3634	alkyl hydroperoxide reductase activity
ATHSA_0497	COG0492	ferredoxin-NADP+ reductase activity
ATHSA_0505	COG4166	transmembrane transport
ATHSA_0506	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ATHSA_0507	COG1105	Belongs to the carbohydrate kinase PfkB family
ATHSA_0508	COG0116	Belongs to the methyltransferase superfamily
ATHSA_0509	COG1045	serine acetyltransferase
ATHSA_0510	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ATHSA_0511	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ATHSA_0511	COG0519	Catalyzes the synthesis of GMP from XMP
ATHSA_0513	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ATHSA_0517	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ATHSA_0518	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ATHSA_0519	COG0740	serine-type endopeptidase activity
ATHSA_0520	COG0544	peptidyl-prolyl cis-trans isomerase activity
ATHSA_0521	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ATHSA_0522	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ATHSA_0523	COG1181	Belongs to the D-alanine--D-alanine ligase family
ATHSA_0524	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ATHSA_0525	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ATHSA_0526	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ATHSA_0527	COG0459	protein refolding
ATHSA_0528	COG0673	inositol 2-dehydrogenase activity
ATHSA_0540	COG2235	arginine
ATHSA_0541	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ATHSA_0545	COG0564	pseudouridine synthase activity
ATHSA_0546	COG0671	phosphoesterase, PA-phosphatase related
ATHSA_0547	COG1420	regulation of RNA biosynthetic process
ATHSA_0548	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ATHSA_0549	COG0484	heat shock protein binding
ATHSA_0554	COG3842	ATPase activity
ATHSA_0560	COG1418	mRNA catabolic process
ATHSA_0561	COG1126	abc transporter atp-binding protein
ATHSA_0563	COG1126	abc transporter atp-binding protein
ATHSA_0564	COG0765	amino acid transport
ATHSA_0567	COG0037	tRNA processing
ATHSA_0568	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ATHSA_0570	COG0745	RESPONSE REGULATOR receiver
ATHSA_0571	COG5002	protein histidine kinase activity
ATHSA_0573	COG2151	metal-sulfur cluster biosynthetic enzyme
ATHSA_0575	COG3956	TIGRFAM MazG family protein
ATHSA_0576	COG1392	Phosphate transport regulator
ATHSA_0579	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ATHSA_0580	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
ATHSA_0582	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ATHSA_0584	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ATHSA_0586	COG1307	EDD domain protein, DegV family
ATHSA_0587	COG1970	mechanosensitive ion channel activity
ATHSA_0589	COG1175	transmembrane transport
ATHSA_0590	COG0395	ABC-type sugar transport system, permease component
ATHSA_0591	COG0084	hydrolase, TatD family'
ATHSA_0592	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ATHSA_0593	COG0606	chelatase, subunit chli
ATHSA_0594	COG0606	chelatase, subunit chli
ATHSA_0600	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ATHSA_0602	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ATHSA_0603	COG0250	Participates in transcription elongation, termination and antitermination
ATHSA_0604	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ATHSA_0605	COG0081	regulation of translation
ATHSA_0606	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ATHSA_0607	COG0222	ribosome binding
ATHSA_0608	COG0085	RNA polymerase activity
ATHSA_0609	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ATHSA_0619	COG0402	S-adenosylhomocysteine deaminase activity
ATHSA_0621	COG1242	4 iron, 4 sulfur cluster binding
ATHSA_0622	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ATHSA_0626	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ATHSA_0629	COG0776	regulation of translation
ATHSA_0632	COG0450	alkyl hydroperoxide reductase
ATHSA_0633	COG1914	H( )-stimulated, divalent metal cation uptake system
ATHSA_0634	COG1815	bacterial-type flagellum-dependent cell motility
ATHSA_0636	COG1677	Flagellar hook-basal body complex protein FliE
ATHSA_0637	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ATHSA_0638	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ATHSA_0645	COG1598	PFAM Uncharacterised protein family UPF0150
ATHSA_0651	COG1598	PFAM Uncharacterised protein family UPF0150
ATHSA_0656	COG3852	Histidine kinase
ATHSA_0658	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
ATHSA_0659	COG0571	ribonuclease III activity
ATHSA_0661	COG1196	nuclear chromosome segregation
ATHSA_0662	COG0481	GTPase activity
ATHSA_0664	COG1515	deoxyribonuclease V activity
ATHSA_0670	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ATHSA_0672	COG2814	Major facilitator Superfamily
ATHSA_0673	COG0138	bifunctional purine biosynthesis protein purh
ATHSA_0674	COG0835	chemotaxis
ATHSA_0675	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ATHSA_0677	COG0489	protein tyrosine kinase activity
ATHSA_0679	COG1214	PFAM Peptidase M22, glycoprotease
ATHSA_0681	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ATHSA_0686	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ATHSA_0688	COG0395	ABC-type sugar transport system, permease component
ATHSA_0693	COG1349	DNA-binding transcription factor activity
ATHSA_0697	COG1175	transmembrane transport
ATHSA_0698	COG0395	ABC-type sugar transport system, permease component
ATHSA_0699	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ATHSA_0701	COG3250	beta-galactosidase activity
ATHSA_0702	COG1486	melibiose metabolic process
ATHSA_0708	COG0569	domain protein
ATHSA_0709	COG0569	domain protein
ATHSA_0711	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ATHSA_0715	COG4191	Histidine kinase
ATHSA_0716	COG2204	response regulator
ATHSA_0719	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ATHSA_0724	COG1362	aminopeptidase activity
ATHSA_0725	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ATHSA_0725	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ATHSA_0729	COG0356	it plays a direct role in the translocation of protons across the membrane
ATHSA_0730	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ATHSA_0731	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ATHSA_0733	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ATHSA_0734	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ATHSA_0735	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ATHSA_0736	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ATHSA_0738	COG2078	PFAM AMMECR1 domain protein
ATHSA_0740	COG2894	cell division
ATHSA_0742	COG0432	Pfam Uncharacterised protein family UPF0047
ATHSA_0745	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ATHSA_0746	COG2362	D-Aminopeptidase
ATHSA_0747	COG0482	sulfurtransferase activity
ATHSA_0751	COG1543	Belongs to the glycosyl hydrolase 57 family
ATHSA_0761	COG0822	iron-sulfur transferase activity
ATHSA_0762	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ATHSA_0763	COG0719	Fe-S assembly protein
ATHSA_0764	COG0719	Fe-S assembly protein
ATHSA_0765	COG0396	ATPase activity
ATHSA_0768	COG4608	Belongs to the ABC transporter superfamily
ATHSA_0769	COG0444	Belongs to the ABC transporter superfamily
ATHSA_0770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ATHSA_0772	COG1268	BioY protein
ATHSA_0773	COG0488	(ABC) transporter
ATHSA_0774	COG2986	histidine ammonia-lyase
ATHSA_0775	COG0557	exoribonuclease II activity
ATHSA_0776	COG1937	Protein conserved in bacteria
ATHSA_0777	COG0793	Belongs to the peptidase S41A family
ATHSA_0777	COG3409	Peptidoglycan-binding domain 1 protein
ATHSA_0779	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ATHSA_0780	COG0228	four-way junction DNA binding
ATHSA_0781	COG1837	Belongs to the UPF0109 family
ATHSA_0782	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ATHSA_0783	COG0336	Belongs to the RNA methyltransferase TrmD family
ATHSA_0784	COG4752	Belongs to the RNA methyltransferase TrmD family
ATHSA_0785	COG0335	large ribosomal subunit rRNA binding
ATHSA_0787	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ATHSA_0788	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ATHSA_0789	COG0850	regulation of cytokinetic process
ATHSA_0790	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ATHSA_0793	COG1555	photosystem II stabilization
ATHSA_0798	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ATHSA_0799	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ATHSA_0801	COG0149	triose-phosphate isomerase activity
ATHSA_0802	COG0149	triose-phosphate isomerase activity
ATHSA_0802	COG0126	phosphoglycerate kinase activity
ATHSA_0804	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ATHSA_0805	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ATHSA_0807	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ATHSA_0810	COG2136	Putative SAM-dependent methyltransferase
ATHSA_0810	COG2521	methyltransferase
ATHSA_0811	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ATHSA_0812	COG1923	regulation of RNA biosynthetic process
ATHSA_0813	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ATHSA_0815	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ATHSA_0816	COG0445	tRNA wobble uridine modification
ATHSA_0817	COG1227	inorganic diphosphatase activity
ATHSA_0817	COG0517	IMP dehydrogenase activity
ATHSA_0826	COG2208	phosphoserine phosphatase activity
ATHSA_0830	COG0248	Ppx GppA phosphatase
ATHSA_0831	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ATHSA_0835	COG0745	RESPONSE REGULATOR receiver
ATHSA_0836	COG0784	Response regulator, receiver
ATHSA_0836	COG2205	protein histidine kinase activity
ATHSA_0837	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ATHSA_0838	COG1704	LemA family
ATHSA_0839	COG0191	fructose-bisphosphate aldolase activity
ATHSA_0840	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ATHSA_0841	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ATHSA_0842	COG1827	regulation of RNA biosynthetic process
ATHSA_0843	COG0477	Major facilitator Superfamily
ATHSA_0847	COG3852	Histidine kinase
ATHSA_0850	COG0517	IMP dehydrogenase activity
ATHSA_0850	COG1125	glycine betaine transport
ATHSA_0852	COG4166	transmembrane transport
ATHSA_0853	COG0601	transmembrane transport
ATHSA_0855	COG0444	Belongs to the ABC transporter superfamily
ATHSA_0856	COG4608	Belongs to the ABC transporter superfamily
ATHSA_0859	COG1449	Belongs to the glycosyl hydrolase 57 family
ATHSA_0860	COG1530	ribonuclease E activity
ATHSA_0861	COG1338	Plays a role in the flagellum-specific transport system
ATHSA_0863	COG2201	protein-glutamate methylesterase activity
ATHSA_0864	COG0835	chemotaxis
ATHSA_0865	COG2198	Histidine kinase
ATHSA_0865	COG0643	Histidine kinase
ATHSA_0873	COG0483	inositol monophosphate 1-phosphatase activity
ATHSA_0874	COG0072	phenylalanine-tRNA ligase activity
ATHSA_0874	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ATHSA_0875	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ATHSA_0876	COG0785	Cytochrome C biogenesis protein
ATHSA_0879	COG0484	heat shock protein binding
ATHSA_0882	COG0366	Alpha amylase catalytic
ATHSA_0883	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ATHSA_0884	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ATHSA_0885	COG3481	metal-dependent phosphohydrolase, HD sub domain
ATHSA_0886	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ATHSA_0887	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ATHSA_0891	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ATHSA_0892	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
ATHSA_0893	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ATHSA_0894	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
ATHSA_0909	COG0842	Transport permease protein
ATHSA_0910	COG4555	ABC transporter
ATHSA_0916	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ATHSA_0918	COG2172	sigma factor antagonist activity
ATHSA_0919	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
ATHSA_0920	COG3437	response regulator, receiver
ATHSA_0920	COG2770	Histidine kinase
ATHSA_0921	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ATHSA_0922	COG1765	OsmC-like protein
ATHSA_0925	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
ATHSA_0926	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ATHSA_0928	COG0367	asparagine synthase
ATHSA_0930	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ATHSA_0933	COG1278	Cold shock
ATHSA_0936	COG1653	transport
ATHSA_0939	COG2814	Major facilitator Superfamily
ATHSA_0940	COG4166	transmembrane transport
ATHSA_0941	COG0601	transmembrane transport
ATHSA_0943	COG0444	Belongs to the ABC transporter superfamily
ATHSA_0944	COG4608	Belongs to the ABC transporter superfamily
ATHSA_0947	COG1013	pyruvate-flavodoxin oxidoreductase activity
ATHSA_0948	COG0674	pyruvate-flavodoxin oxidoreductase activity
ATHSA_0948	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ATHSA_0950	COG0768	penicillin binding
ATHSA_0952	COG0275	rRNA processing
ATHSA_0953	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ATHSA_0955	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ATHSA_0956	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ATHSA_0957	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ATHSA_0958	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ATHSA_0959	COG1461	Dihydroxyacetone kinase
ATHSA_0961	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ATHSA_0962	COG1722	exodeoxyribonuclease VII activity
ATHSA_0963	COG1570	exodeoxyribonuclease VII activity
ATHSA_0964	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ATHSA_0965	COG2759	Belongs to the formate--tetrahydrofolate ligase family
ATHSA_0967	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ATHSA_0968	COG0006	proline dipeptidase activity
ATHSA_0970	COG0574	Belongs to the PEP-utilizing enzyme family
ATHSA_0970	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ATHSA_0971	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ATHSA_0973	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ATHSA_0978	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ATHSA_0978	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ATHSA_0979	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ATHSA_0980	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ATHSA_0981	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ATHSA_0982	COG0512	Glutamine amidotransferase of anthranilate synthase
ATHSA_0982	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ATHSA_0986	COG0135	phosphoribosylanthranilate isomerase activity
ATHSA_0989	COG0497	DNA recombination
ATHSA_0990	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ATHSA_0993	COG5012	cobalamin binding
ATHSA_0999	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ATHSA_1000	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ATHSA_1002	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ATHSA_1003	COG0305	Participates in initiation and elongation during chromosome replication
ATHSA_1005	COG0704	Plays a role in the regulation of phosphate uptake
ATHSA_1007	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ATHSA_1008	COG0581	inorganic phosphate transmembrane transporter activity
ATHSA_1009	COG0573	inorganic phosphate transmembrane transporter activity
ATHSA_1011	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ATHSA_1013	COG0427	acetyl-CoA hydrolase
ATHSA_1014	COG1028	Short-chain dehydrogenase reductase Sdr
ATHSA_1015	COG0183	Belongs to the thiolase family
ATHSA_1024	COG0477	Major facilitator Superfamily
ATHSA_1025	COG0737	Belongs to the 5'-nucleotidase family
ATHSA_1026	COG1151	hydroxylamine reductase activity
ATHSA_1028	COG2046	Belongs to the sulfate adenylyltransferase family
ATHSA_1030	COG0529	Catalyzes the synthesis of activated sulfate
ATHSA_1031	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ATHSA_1035	COG1157	protein secretion by the type III secretion system
ATHSA_1036	COG1592	Rubrerythrin
ATHSA_1037	COG0531	amino acid
ATHSA_1038	COG1481	regulation of sporulation
ATHSA_1039	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ATHSA_1040	COG1660	Displays ATPase and GTPase activities
ATHSA_1044	COG1085	galactose-1-phosphate uridylyltransferase
ATHSA_1045	COG0297	glycogen (starch) synthase activity
ATHSA_1047	COG1178	ABC-type Fe3 transport system permease component
ATHSA_1054	COG1653	transport
ATHSA_1056	COG0395	ABC-type sugar transport system, permease component
ATHSA_1058	COG3459	Glycosyltransferase 36 associated
ATHSA_1063	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ATHSA_1064	COG0083	homoserine kinase activity
ATHSA_1066	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ATHSA_1067	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ATHSA_1068	COG0765	amino acid transport
ATHSA_1069	COG1126	abc transporter atp-binding protein
ATHSA_1071	COG0110	maltose O-acetyltransferase activity
ATHSA_1073	COG1122	ATPase activity
ATHSA_1074	COG1122	ATPase activity
ATHSA_1075	COG2813	Specifically methylates the guanine in position
ATHSA_1077	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ATHSA_1078	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ATHSA_1080	COG5002	protein histidine kinase activity
ATHSA_1082	COG0704	Plays a role in the regulation of phosphate uptake
ATHSA_1083	COG0840	transmembrane signaling receptor activity
ATHSA_1084	COG1490	D-aminoacyl-tRNA deacylase activity
ATHSA_1085	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ATHSA_1095	COG0395	ABC-type sugar transport system, permease component
ATHSA_1096	COG1175	transmembrane transport
ATHSA_1097	COG0673	inositol 2-dehydrogenase activity
ATHSA_1098	COG1349	DNA-binding transcription factor activity
ATHSA_1101	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ATHSA_1103	COG1131	(ABC) transporter
ATHSA_1105	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ATHSA_1111	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ATHSA_1117	COG0511	ligase activity, forming carbon-carbon bonds
ATHSA_1119	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ATHSA_1120	COG0346	lactoylglutathione lyase activity
ATHSA_1122	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ATHSA_1123	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ATHSA_1126	COG1335	isochorismatase
ATHSA_1128	COG1131	(ABC) transporter
ATHSA_1130	COG0698	ribose 5-phosphate isomerase
ATHSA_1132	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
ATHSA_1133	COG0193	aminoacyl-tRNA hydrolase activity
ATHSA_1134	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ATHSA_1135	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ATHSA_1136	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ATHSA_1137	COG0632	four-way junction helicase activity
ATHSA_1138	COG0285	dihydrofolate synthase activity
ATHSA_1139	COG0525	valine-tRNA ligase activity
ATHSA_1142	COG1278	Cold shock
ATHSA_1143	COG0735	belongs to the Fur family
ATHSA_1146	COG0395	ABC-type sugar transport system, permease component
ATHSA_1147	COG1175	transmembrane transport
ATHSA_1151	COG1098	S1 RNA binding domain
ATHSA_1152	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ATHSA_1154	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ATHSA_1155	COG0509	glycine decarboxylation via glycine cleavage system
ATHSA_1156	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ATHSA_1157	COG0156	8-amino-7-oxononanoate synthase activity
ATHSA_1158	COG1063	alcohol dehydrogenase
ATHSA_1163	COG1141	Ferredoxin
ATHSA_1166	COG0617	tRNA 3'-terminal CCA addition
ATHSA_1169	COG1131	(ABC) transporter
ATHSA_1170	COG1469	GTP cyclohydrolase I activity
ATHSA_1174	COG1477	protein flavinylation
ATHSA_1176	COG0424	maF-like protein
ATHSA_1178	COG1918	ferrous iron import across plasma membrane
ATHSA_1178	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ATHSA_1183	COG1032	radical SAM domain protein
ATHSA_1185	COG2267	carboxylic ester hydrolase activity
ATHSA_1189	COG2359	stage V sporulation protein S
ATHSA_1195	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
ATHSA_1196	COG1040	competence protein
ATHSA_1211	COG1573	uracil-dna glycosylase
ATHSA_1212	COG0124	histidyl-tRNA synthetase
ATHSA_1213	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ATHSA_1214	COG5012	cobalamin binding
ATHSA_1216	COG2199	diguanylate cyclase activity
ATHSA_1216	COG2203	Gaf domain
ATHSA_1218	COG0667	Aldo Keto reductase
ATHSA_1219	COG1575	Belongs to the MenA family. Type 1 subfamily
ATHSA_1220	COG1252	NADH dehydrogenase
ATHSA_1221	COG0655	NAD(P)H dehydrogenase (quinone) activity
ATHSA_1227	COG0346	lactoylglutathione lyase activity
ATHSA_1228	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ATHSA_1233	COG0438	transferase activity, transferring glycosyl groups
ATHSA_1235	COG0297	glycogen (starch) synthase activity
ATHSA_1236	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
ATHSA_1246	COG0592	DNA-directed DNA polymerase activity
ATHSA_1247	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ATHSA_1248	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ATHSA_1249	COG2045	Belongs to the ComB family
ATHSA_1250	COG0741	lytic transglycosylase activity
ATHSA_1251	COG1078	dGTPase activity
ATHSA_1254	COG0811	peptide transport
ATHSA_1255	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ATHSA_1256	COG1394	ATPase activity, coupled to movement of substances
ATHSA_1257	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
ATHSA_1258	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
ATHSA_1262	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ATHSA_1263	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ATHSA_1264	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ATHSA_1265	COG3829	transcription factor binding
ATHSA_1265	COG3290	protein histidine kinase activity
ATHSA_1266	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ATHSA_1268	COG2255	four-way junction helicase activity
ATHSA_1269	COG0017	Asparaginyl-tRNA synthetase
ATHSA_1273	COG0602	queuosine metabolic process
ATHSA_1282	COG0004	ammonium transporteR
ATHSA_1287	COG4974	Belongs to the 'phage' integrase family
ATHSA_1288	COG1024	Enoyl-CoA hydratase
ATHSA_1293	COG2814	Major facilitator Superfamily
ATHSA_1298	COG0656	L-ascorbic acid biosynthetic process
ATHSA_1300	COG0346	lactoylglutathione lyase activity
ATHSA_1304	COG1028	Short-chain dehydrogenase reductase Sdr
ATHSA_1305	COG0823	Involved in the tonB-independent uptake of proteins
ATHSA_1305	COG1506	peptidase
ATHSA_1305	COG4946	Tricorn protease homolog
ATHSA_1306	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ATHSA_1307	COG0594	ribonuclease P activity
ATHSA_1308	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ATHSA_1309	COG0706	membrane insertase activity
ATHSA_1310	COG1847	R3H domain protein
ATHSA_1312	COG1228	amidohydrolase
ATHSA_1313	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ATHSA_1314	COG4535	Mg2 and Co2 transporter CorC
ATHSA_1320	COG0363	glucosamine-6-phosphate deaminase activity
ATHSA_1321	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ATHSA_1322	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
ATHSA_1323	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ATHSA_1325	COG0436	Aminotransferase
ATHSA_1326	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ATHSA_1327	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ATHSA_1328	COG0674	pyruvate-flavodoxin oxidoreductase activity
ATHSA_1328	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ATHSA_1330	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ATHSA_1331	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ATHSA_1333	COG0604	alcohol dehydrogenase
ATHSA_1334	COG0395	ABC-type sugar transport system, permease component
ATHSA_1335	COG1175	transmembrane transport
ATHSA_1338	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ATHSA_1339	COG2211	Major facilitator Superfamily
ATHSA_1341	COG5001	Diguanylate cyclase
ATHSA_1341	COG1716	ATPase activity
ATHSA_1344	COG0584	glycerophosphoryl diester phosphodiesterase
ATHSA_1347	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ATHSA_1348	COG1940	carbohydrate kinase activity
ATHSA_1350	COG0626	cystathionine gamma-synthase activity
ATHSA_1351	COG0395	ABC-type sugar transport system, permease component
ATHSA_1353	COG1653	transport
ATHSA_1354	COG1940	carbohydrate kinase activity
ATHSA_1358	COG4608	Belongs to the ABC transporter superfamily
ATHSA_1359	COG0444	Belongs to the ABC transporter superfamily
ATHSA_1361	COG0601	transmembrane transport
ATHSA_1362	COG0747	negative chemotaxis
ATHSA_1363	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ATHSA_1366	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ATHSA_1368	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ATHSA_1369	COG1160	GTP binding
ATHSA_1370	COG2183	response to ionizing radiation
ATHSA_1370	COG0539	negative regulation of cytoplasmic translation
ATHSA_1371	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ATHSA_1372	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ATHSA_1373	COG1366	Belongs to the anti-sigma-factor antagonist family
ATHSA_1374	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ATHSA_1379	COG1937	Protein conserved in bacteria
ATHSA_1389	COG2226	methyltransferase
ATHSA_1390	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ATHSA_1391	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ATHSA_1392	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ATHSA_1393	COG2205	protein histidine kinase activity
ATHSA_1394	COG0477	Major facilitator Superfamily
ATHSA_1396	COG0778	Nitroreductase
ATHSA_1399	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ATHSA_1401	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ATHSA_1402	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ATHSA_1404	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ATHSA_1405	COG1728	Protein conserved in bacteria
ATHSA_1406	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ATHSA_1407	COG1774	PSP1 C-terminal conserved region
ATHSA_1408	COG0343	queuine tRNA-ribosyltransferase activity
ATHSA_1409	COG0489	protein tyrosine kinase activity
ATHSA_1410	COG0442	prolyl-tRNA aminoacylation
ATHSA_1411	COG0552	protein localization to endoplasmic reticulum
ATHSA_1417	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ATHSA_1418	COG0416	fatty acid biosynthetic process
ATHSA_1419	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ATHSA_1420	COG0799	negative regulation of ribosome biogenesis
ATHSA_1421	COG0495	leucyl-tRNA aminoacylation
ATHSA_1422	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ATHSA_1424	COG0583	DNA-binding transcription factor activity
ATHSA_1425	COG3842	ATPase activity
ATHSA_1426	COG0366	Alpha amylase catalytic
ATHSA_1427	COG0860	N-Acetylmuramoyl-L-alanine amidase
ATHSA_1428	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ATHSA_1429	COG1607	acyl-coa hydrolase
ATHSA_1430	COG3246	L-lysine catabolic process to acetate
ATHSA_1431	COG1862	Preprotein translocase
ATHSA_1432	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ATHSA_1433	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ATHSA_1435	COG0237	dephospho-CoA kinase activity
ATHSA_1436	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ATHSA_1437	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ATHSA_1438	COG0519	Catalyzes the synthesis of GMP from XMP
ATHSA_1438	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ATHSA_1440	COG0154	amidase activity
ATHSA_1441	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ATHSA_1442	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ATHSA_1443	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ATHSA_1443	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ATHSA_1444	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ATHSA_1444	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ATHSA_1453	COG3328	transposase activity
ATHSA_1457	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ATHSA_1465	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ATHSA_1466	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ATHSA_1467	COG0196	riboflavin kinase activity
ATHSA_1469	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ATHSA_1470	COG1185	polyribonucleotide nucleotidyltransferase activity
ATHSA_1471	COG0612	Peptidase, M16
ATHSA_1472	COG3437	response regulator, receiver
ATHSA_1475	COG1834	amidinotransferase
ATHSA_1477	COG1473	amidohydrolase
ATHSA_1478	COG1028	Short-chain dehydrogenase reductase Sdr
ATHSA_1481	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ATHSA_1488	COG1131	(ABC) transporter
ATHSA_1489	COG0842	Transport permease protein
ATHSA_1491	COG2096	Adenosyltransferase
ATHSA_1492	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ATHSA_1493	COG0438	transferase activity, transferring glycosyl groups
ATHSA_1495	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ATHSA_1497	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
ATHSA_1498	COG0556	nucleotide-excision repair
ATHSA_1499	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ATHSA_1502	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
ATHSA_1503	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ATHSA_1504	COG4166	transmembrane transport
ATHSA_1505	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ATHSA_1506	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ATHSA_1509	COG0577	efflux transmembrane transporter activity
ATHSA_1509	COG1136	(ABC) transporter
ATHSA_1510	COG0322	excinuclease ABC activity
ATHSA_1511	COG1435	thymidine kinase activity
ATHSA_1513	COG0174	glutamine synthetase
ATHSA_1514	COG1012	belongs to the aldehyde dehydrogenase family
ATHSA_1515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ATHSA_1518	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ATHSA_1518	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ATHSA_1522	COG0582	viral genome integration into host DNA
ATHSA_1523	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ATHSA_1528	COG4221	oxidoreductase activity
ATHSA_1529	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ATHSA_1530	COG1027	Aspartate ammonia-lyase
ATHSA_1531	COG1760	l-serine dehydratase
ATHSA_1532	COG1760	l-serine dehydratase
ATHSA_1534	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ATHSA_1535	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ATHSA_1536	COG2171	N-acyltransferase activity
ATHSA_1537	COG0527	aspartate kinase activity
ATHSA_1538	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ATHSA_1539	COG1473	amidohydrolase
ATHSA_1542	COG0642	Histidine kinase
ATHSA_1543	COG2814	Major facilitator Superfamily
ATHSA_1548	COG1136	(ABC) transporter
ATHSA_1556	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
ATHSA_1561	COG0463	Glycosyl transferase, family 2
ATHSA_1562	COG0170	dolichyl monophosphate biosynthetic process
ATHSA_1567	COG1523	belongs to the glycosyl hydrolase 13 family
ATHSA_1568	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
ATHSA_1569	COG1518	maintenance of DNA repeat elements
ATHSA_1570	COG1518	maintenance of DNA repeat elements
ATHSA_1576	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ATHSA_1603	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ATHSA_1604	COG0673	inositol 2-dehydrogenase activity
ATHSA_1606	COG1410	methionine synthase
ATHSA_1606	COG0646	methionine synthase
ATHSA_1607	COG1122	ATPase activity
ATHSA_1611	COG1131	(ABC) transporter
ATHSA_1612	COG0747	negative chemotaxis
ATHSA_1615	COG1863	multisubunit Na H antiporter MnhE subunit
ATHSA_1619	COG2111	Na H antiporter
ATHSA_1619	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ATHSA_1621	COG0651	ATP synthesis coupled electron transport
ATHSA_1622	COG1007	ATP synthesis coupled electron transport
ATHSA_1623	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ATHSA_1624	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ATHSA_1626	COG0649	NAD binding
ATHSA_1627	COG0493	'glutamate synthase
ATHSA_1628	COG0543	2 iron, 2 sulfur cluster binding
ATHSA_1630	COG4608	Belongs to the ABC transporter superfamily
ATHSA_1631	COG0444	Belongs to the ABC transporter superfamily
ATHSA_1634	COG0747	negative chemotaxis
ATHSA_1635	COG1307	EDD domain protein, DegV family
ATHSA_1637	COG0437	4 iron, 4 sulfur cluster binding
ATHSA_1638	COG0640	Transcriptional regulator
ATHSA_1641	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ATHSA_1642	COG3426	butyrate kinase activity
ATHSA_1643	COG0280	phosphate acetyltransferase
ATHSA_1644	COG3426	butyrate kinase activity
ATHSA_1650	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ATHSA_1651	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
ATHSA_1652	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ATHSA_1654	COG0303	'Molybdopterin
ATHSA_1655	COG0521	Mo-molybdopterin cofactor biosynthetic process
ATHSA_1656	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ATHSA_1657	COG1085	galactose-1-phosphate uridylyltransferase
ATHSA_1658	COG3345	alpha-galactosidase
ATHSA_1661	COG0395	ABC-type sugar transport system, permease component
ATHSA_1662	COG1175	transmembrane transport
ATHSA_1664	COG1609	Transcriptional regulator
ATHSA_1666	COG0360	Binds together with S18 to 16S ribosomal RNA
ATHSA_1667	COG0629	single-stranded DNA binding
ATHSA_1669	COG0359	binds to the 23S rRNA
ATHSA_1670	COG1234	tRNA 3'-trailer cleavage
ATHSA_1676	COG1546	Belongs to the CinA family
ATHSA_1676	COG1058	Belongs to the CinA family
ATHSA_1677	COG0494	nUDIX hydrolase
ATHSA_1679	COG0728	peptidoglycan biosynthetic process
ATHSA_1682	COG1028	Short-chain dehydrogenase reductase Sdr
ATHSA_1684	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ATHSA_1686	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ATHSA_1689	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ATHSA_1690	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ATHSA_1695	COG1175	transmembrane transport
ATHSA_1697	COG0371	Dehydrogenase
ATHSA_1700	COG0395	ABC-type sugar transport system, permease component
ATHSA_1701	COG1175	transmembrane transport
ATHSA_1703	COG2160	L-arabinose isomerase activity
ATHSA_1706	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ATHSA_1707	COG0747	negative chemotaxis
ATHSA_1708	COG0601	transmembrane transport
ATHSA_1709	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ATHSA_1710	COG0444	Belongs to the ABC transporter superfamily
ATHSA_1711	COG4608	Belongs to the ABC transporter superfamily
ATHSA_1712	COG2814	Major facilitator Superfamily
ATHSA_1713	COG3876	Protein conserved in bacteria
ATHSA_1716	COG1472	Belongs to the glycosyl hydrolase 3 family
ATHSA_1718	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ATHSA_1719	COG2188	Transcriptional regulator
ATHSA_1721	COG0791	NLP P60 protein
ATHSA_1722	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ATHSA_1724	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ATHSA_1725	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
ATHSA_1726	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ATHSA_1727	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ATHSA_1728	COG0358	DNA primase activity
ATHSA_1729	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ATHSA_1731	COG0446	pyridine nucleotide-disulphide oxidoreductase
ATHSA_1733	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
ATHSA_1734	COG0395	ABC-type sugar transport system, permease component
ATHSA_1735	COG1175	transmembrane transport
ATHSA_1738	COG1609	Transcriptional regulator
ATHSA_1740	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ATHSA_1741	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ATHSA_1742	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ATHSA_1743	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ATHSA_1745	COG0402	S-adenosylhomocysteine deaminase activity
ATHSA_1748	COG1129	ABC transporter
ATHSA_1749	COG1172	Belongs to the binding-protein-dependent transport system permease family
ATHSA_1750	COG1879	ABC-type sugar transport system periplasmic component
ATHSA_1752	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ATHSA_1755	COG1940	carbohydrate kinase activity
ATHSA_1760	COG1994	Peptidase M50
ATHSA_1761	COG0564	pseudouridine synthase activity
ATHSA_1763	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ATHSA_1768	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
ATHSA_1769	COG1691	(AIR) carboxylase
ATHSA_1770	COG1606	tRNA processing
ATHSA_1774	COG1959	2 iron, 2 sulfur cluster binding
ATHSA_1776	COG1773	rubredoxin
ATHSA_1777	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ATHSA_1778	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ATHSA_1780	COG3579	cysteine-type endopeptidase activity
ATHSA_1781	COG3706	GGDEF domain
ATHSA_1782	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ATHSA_1784	COG2264	protein methyltransferase activity
ATHSA_1789	COG1162	GTPase activity
ATHSA_1790	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ATHSA_1791	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ATHSA_1792	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ATHSA_1792	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ATHSA_1794	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ATHSA_1800	COG1703	isobutyryl-CoA mutase activity
ATHSA_1801	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ATHSA_1801	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ATHSA_1802	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ATHSA_1802	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ATHSA_1803	COG0587	DNA-directed DNA polymerase activity
ATHSA_1804	COG1136	(ABC) transporter
ATHSA_1807	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ATHSA_1808	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ATHSA_1809	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ATHSA_1810	COG1984	allophanate hydrolase subunit 2
ATHSA_1811	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ATHSA_1812	COG2313	pseudouridylate synthase activity
ATHSA_1813	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ATHSA_1814	COG1334	flagellar protein FlaG
ATHSA_1816	COG0438	transferase activity, transferring glycosyl groups
ATHSA_1821	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ATHSA_1822	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ATHSA_1824	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ATHSA_1825	COG2264	protein methyltransferase activity
ATHSA_1828	COG1193	negative regulation of DNA recombination
ATHSA_1830	COG3620	sequence-specific DNA binding
ATHSA_1830	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ATHSA_1830	COG0617	tRNA 3'-terminal CCA addition
ATHSA_1832	COG0254	rRNA binding
ATHSA_1833	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ATHSA_1834	COG2414	aldehyde ferredoxin oxidoreductase
ATHSA_1838	COG0280	phosphate acetyltransferase
ATHSA_1839	COG0019	diaminopimelate decarboxylase activity
ATHSA_1840	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ATHSA_1841	COG1067	ATP-dependent peptidase activity
ATHSA_1843	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ATHSA_1844	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ATHSA_1845	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ATHSA_1847	COG0589	response to stress
ATHSA_1848	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ATHSA_1850	COG0205	6-phosphofructokinase activity
ATHSA_1851	COG0469	pyruvate kinase activity
ATHSA_1853	COG0205	6-phosphofructokinase activity
ATHSA_1854	COG0586	Pfam SNARE associated Golgi protein
ATHSA_1855	COG3437	response regulator, receiver
ATHSA_1855	COG2770	Histidine kinase
ATHSA_1856	COG0737	Belongs to the 5'-nucleotidase family
ATHSA_1859	COG0052	Belongs to the universal ribosomal protein uS2 family
ATHSA_1861	COG1653	transport
ATHSA_1862	COG1175	transmembrane transport
ATHSA_1863	COG0395	ABC-type sugar transport system, permease component
ATHSA_1864	COG4948	Mandelate Racemase Muconate Lactonizing
ATHSA_1866	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ATHSA_1869	COG0366	Alpha amylase catalytic
ATHSA_1870	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ATHSA_1871	COG2003	Belongs to the UPF0758 family
ATHSA_1873	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ATHSA_1873	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ATHSA_1876	COG1278	Cold shock
ATHSA_1883	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ATHSA_1884	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ATHSA_1885	COG0215	cysteine-tRNA ligase activity
ATHSA_1887	COG0187	DNA topoisomerase II activity
ATHSA_1889	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ATHSA_1890	COG2176	DNA-directed DNA polymerase activity
ATHSA_1902	COG2204	response regulator
ATHSA_1904	COG1121	(ABC) transporter
ATHSA_1905	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ATHSA_1909	COG2894	cell division
ATHSA_1911	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ATHSA_1911	COG0731	radical SAM domain protein
ATHSA_1912	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ATHSA_1915	COG3250	beta-galactosidase activity
ATHSA_1916	COG2723	6-phospho-beta-galactosidase activity
ATHSA_1917	COG3534	alpha-L-arabinofuranosidase
ATHSA_1918	COG1609	Transcriptional regulator
ATHSA_1919	COG4608	Belongs to the ABC transporter superfamily
ATHSA_1920	COG0444	Belongs to the ABC transporter superfamily
ATHSA_1921	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ATHSA_1924	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ATHSA_1925	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ATHSA_1928	COG0542	response to heat
ATHSA_1930	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
ATHSA_1931	COG4956	integral membrane protein (PIN domain superfamily)
ATHSA_1932	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ATHSA_1933	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ATHSA_1938	COG0210	DNA helicase
ATHSA_1942	COG0736	holo-[acyl-carrier-protein] synthase activity
ATHSA_1945	COG3833	ABC-type maltose transport systems, permease component
ATHSA_1946	COG1175	transmembrane transport
ATHSA_1949	COG0366	Alpha amylase catalytic
ATHSA_1951	COG0300	oxidoreductase activity
ATHSA_1953	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
ATHSA_1961	COG0195	Participates in both transcription termination and antitermination
ATHSA_1964	COG0174	glutamine synthetase
ATHSA_1970	COG0798	PFAM Bile acid sodium symporter
ATHSA_1971	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ATHSA_1975	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ATHSA_1977	COG1132	(ABC) transporter
ATHSA_p10003	COG0776	regulation of translation
ATHSA_p10004	COG1923	regulation of RNA biosynthetic process
ATHSA_p10011	COG1396	sequence-specific DNA binding
ATHSA_p10016	COG2189	Belongs to the N(4) N(6)-methyltransferase family
ATHSA_p10020	COG2203	Gaf domain
ATHSA_p10020	COG2199	diguanylate cyclase activity
ATHSA_p10021	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ATHSA_p10029	COG4974	Belongs to the 'phage' integrase family
ATHSA_p10037	COG4166	transmembrane transport
ATHSA_p10038	COG1940	carbohydrate kinase activity
ATHSA_p10042	COG1192	Involved in chromosome partitioning
ATHSA_p20003	COG1192	Involved in chromosome partitioning
ATHSA_p20016	COG3328	transposase activity
ATHSA_p20021	COG4974	Belongs to the 'phage' integrase family
ATHSA_p20022	COG3328	transposase activity
ATHSA_p20026	COG0426	domain, Protein
ATHSA_p20032	COG3328	transposase activity
ATHSA_p20033	COG3328	transposase activity
ATHSA_p20034	COG2189	Belongs to the N(4) N(6)-methyltransferase family
ATHSA_p20036	COG3328	transposase activity
ATHSA_p20044	COG1923	regulation of RNA biosynthetic process
ATHSA_p20045	COG0776	regulation of translation
ATHSA_p20046	COG3189	MarR family transcriptional regulator