locus-tag	class	description
ATOBIA_N00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ATOBIA_N00030	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ATOBIA_N00050	COG0187	DNA topoisomerase II activity
ATOBIA_N00060	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ATOBIA_N00080	COG0765	amino acid transport
ATOBIA_N00100	COG1472	Belongs to the glycosyl hydrolase 3 family
ATOBIA_N00120	COG1217	gtp-binding protein TYPA
ATOBIA_N00130	COG1201	RNA secondary structure unwinding
ATOBIA_N00150	COG2860	membrane
ATOBIA_N00170	COG0360	Binds together with S18 to 16S ribosomal RNA
ATOBIA_N00180	COG0629	single-stranded DNA binding
ATOBIA_N00190	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ATOBIA_N00210	COG0359	binds to the 23S rRNA
ATOBIA_N00220	COG0305	Participates in initiation and elongation during chromosome replication
ATOBIA_N00230	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ATOBIA_N00270	COG5002	protein histidine kinase activity
ATOBIA_N00280	COG0745	RESPONSE REGULATOR receiver
ATOBIA_N00310	COG1132	(ABC) transporter
ATOBIA_N00320	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ATOBIA_N00340	COG0351	phosphomethylpyrimidine kinase
ATOBIA_N00350	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ATOBIA_N00370	COG4509	Sortase family
ATOBIA_N00380	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ATOBIA_N00460	COG3414	Phosphotransferase system galactitol-specific IIB component
ATOBIA_N00480	COG0235	Class ii aldolase
ATOBIA_N00490	COG3775	system Galactitol-specific IIC component
ATOBIA_N00500	COG2376	Dihydroxyacetone kinase
ATOBIA_N00520	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ATOBIA_N00560	COG2957	Belongs to the agmatine deiminase family
ATOBIA_N00580	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ATOBIA_N00590	COG0531	amino acid
ATOBIA_N00610	COG0531	amino acid
ATOBIA_N00620	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ATOBIA_N00620	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ATOBIA_N00620	COG1013	pyruvate-flavodoxin oxidoreductase activity
ATOBIA_N00620	COG0674	pyruvate-flavodoxin oxidoreductase activity
ATOBIA_N00640	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ATOBIA_N00690	COG3275	phosphorelay sensor kinase activity
ATOBIA_N00700	COG3279	Response regulator of the LytR AlgR family
ATOBIA_N00730	COG0671	phosphoesterase, PA-phosphatase related
ATOBIA_N00740	COG3118	belongs to the thioredoxin family
ATOBIA_N00830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ATOBIA_N00840	COG1028	Short-chain dehydrogenase reductase Sdr
ATOBIA_N00850	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ATOBIA_N00890	COG1349	DNA-binding transcription factor activity
ATOBIA_N00930	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ATOBIA_N00940	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ATOBIA_N00950	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ATOBIA_N00960	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ATOBIA_N00980	COG2239	Acts as a magnesium transporter
ATOBIA_N01010	COG1882	Formate acetyltransferase
ATOBIA_N01020	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ATOBIA_N01030	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ATOBIA_N01070	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ATOBIA_N01120	COG0513	Belongs to the DEAD box helicase family
ATOBIA_N01130	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ATOBIA_N01180	COG1704	LemA family
ATOBIA_N01190	COG0622	Phosphoesterase
ATOBIA_N01220	COG0017	Asparaginyl-tRNA synthetase
ATOBIA_N01260	COG0493	'glutamate synthase
ATOBIA_N01260	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ATOBIA_N01280	COG0515	serine threonine protein kinase
ATOBIA_N01360	COG0443	Heat shock 70 kDa protein
ATOBIA_N01370	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ATOBIA_N01380	COG0484	heat shock protein binding
ATOBIA_N01390	COG0789	Transcriptional regulator
ATOBIA_N01400	COG0542	response to heat
ATOBIA_N01410	COG0515	serine threonine protein kinase
ATOBIA_N01410	COG2815	serine threonine protein kinase
ATOBIA_N01440	COG2188	Transcriptional regulator
ATOBIA_N01460	COG2188	Transcriptional regulator
ATOBIA_N01470	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ATOBIA_N01480	COG1482	cell wall glycoprotein biosynthetic process
ATOBIA_N01500	COG3715	PTS system
ATOBIA_N01510	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ATOBIA_N01530	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ATOBIA_N01540	COG1482	cell wall glycoprotein biosynthetic process
ATOBIA_N01560	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ATOBIA_N01570	COG0037	tRNA processing
ATOBIA_N01580	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ATOBIA_N01580	COG0037	tRNA processing
ATOBIA_N01590	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ATOBIA_N01600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ATOBIA_N01640	COG2188	Transcriptional regulator
ATOBIA_N01700	COG3716	PTS system mannose fructose sorbose family IID component
ATOBIA_N01720	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ATOBIA_N01730	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ATOBIA_N01740	COG4619	ABC transporter
ATOBIA_N01750	COG0390	transport system, permease component
ATOBIA_N01760	COG0436	Aminotransferase
ATOBIA_N01770	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ATOBIA_N01780	COG0708	Exodeoxyribonuclease III
ATOBIA_N01800	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ATOBIA_N01810	COG0302	gtp cyclohydrolase
ATOBIA_N01840	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ATOBIA_N01850	COG0254	rRNA binding
ATOBIA_N01870	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ATOBIA_N01880	COG2890	protein-(glutamine-N5) methyltransferase activity
ATOBIA_N01890	COG0009	L-threonylcarbamoyladenylate synthase
ATOBIA_N01900	COG0698	ribose 5-phosphate isomerase
ATOBIA_N01910	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ATOBIA_N01930	COG0356	it plays a direct role in the translocation of protons across the membrane
ATOBIA_N01960	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ATOBIA_N01970	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ATOBIA_N01980	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ATOBIA_N01990	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ATOBIA_N02010	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ATOBIA_N02040	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ATOBIA_N02050	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ATOBIA_N02070	COG0653	protein targeting
ATOBIA_N02080	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ATOBIA_N02090	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ATOBIA_N02110	COG2884	Cell division ATP-binding protein ftsE
ATOBIA_N02120	COG2177	Part of the ABC transporter FtsEX involved in
ATOBIA_N02130	COG0557	exoribonuclease II activity
ATOBIA_N02150	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ATOBIA_N02160	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ATOBIA_N02160	COG1773	rubredoxin
ATOBIA_N02280	COG2188	Transcriptional regulator
ATOBIA_N02290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ATOBIA_N02290	COG1263	PTS System
ATOBIA_N02300	COG1486	melibiose metabolic process
ATOBIA_N02320	COG2190	(PTS) system
ATOBIA_N02360	COG1131	(ABC) transporter
ATOBIA_N02370	COG2197	response regulator
ATOBIA_N02390	COG1105	Belongs to the carbohydrate kinase PfkB family
ATOBIA_N02400	COG4667	esterase of the alpha-beta hydrolase superfamily
ATOBIA_N02420	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ATOBIA_N02430	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ATOBIA_N02440	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ATOBIA_N02450	COG0736	holo-[acyl-carrier-protein] synthase activity
ATOBIA_N02460	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ATOBIA_N02460	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ATOBIA_N02470	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ATOBIA_N02480	COG1573	uracil-dna glycosylase
ATOBIA_N02490	COG0802	atpase or kinase
ATOBIA_N02510	COG0745	RESPONSE REGULATOR receiver
ATOBIA_N02550	COG1609	Transcriptional regulator
ATOBIA_N02560	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ATOBIA_N02570	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ATOBIA_N02590	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ATOBIA_N02600	COG1373	ATPase (AAA superfamily
ATOBIA_N02640	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ATOBIA_N02650	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ATOBIA_N02660	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ATOBIA_N02660	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ATOBIA_N02660	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ATOBIA_N02670	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ATOBIA_N02680	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ATOBIA_N02690	COG0066	3-isopropylmalate dehydratase activity
ATOBIA_N02700	COG0473	3-isopropylmalate dehydrogenase activity
ATOBIA_N02750	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ATOBIA_N02770	COG4750	Nucleotidyl transferase
ATOBIA_N02780	COG0697	spore germination
ATOBIA_N02790	COG3475	LICD family
ATOBIA_N02810	COG0706	membrane insertase activity
ATOBIA_N02850	COG3885	ferrous iron binding
ATOBIA_N02850	COG2078	PFAM AMMECR1 domain protein
ATOBIA_N02910	COG4120	Belongs to the binding-protein-dependent transport system permease family
ATOBIA_N02920	COG3842	ATPase activity
ATOBIA_N02940	COG0586	Pfam SNARE associated Golgi protein
ATOBIA_N02950	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ATOBIA_N02960	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ATOBIA_N02970	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ATOBIA_N03000	COG1136	(ABC) transporter
ATOBIA_N03060	COG1194	a g-specific adenine glycosylase
ATOBIA_N03070	COG1592	Rubrerythrin
ATOBIA_N03090	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ATOBIA_N03100	COG0058	SHG alpha-glucan phosphorylase activity
ATOBIA_N03120	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ATOBIA_N03130	COG0297	glycogen (starch) synthase activity
ATOBIA_N03150	COG0778	Nitroreductase
ATOBIA_N03180	COG0366	Alpha amylase catalytic
ATOBIA_N03270	COG0012	GTP binding
ATOBIA_N03290	COG1882	Formate acetyltransferase
ATOBIA_N03300	COG1882	Formate acetyltransferase
ATOBIA_N03370	COG0586	Pfam SNARE associated Golgi protein
ATOBIA_N03460	COG3706	GGDEF domain
ATOBIA_N03470	COG2205	protein histidine kinase activity
ATOBIA_N03470	COG5002	protein histidine kinase activity
ATOBIA_N03470	COG0784	Response regulator, receiver
ATOBIA_N03490	COG3437	response regulator, receiver
ATOBIA_N03510	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ATOBIA_N03540	COG1316	TRANSCRIPTIONal
ATOBIA_N03550	COG0519	Catalyzes the synthesis of GMP from XMP
ATOBIA_N03570	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ATOBIA_N03590	COG4974	Belongs to the 'phage' integrase family
ATOBIA_N03610	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
ATOBIA_N03770	COG0549	Belongs to the carbamate kinase family
ATOBIA_N03820	COG3077	Addiction module antitoxin, RelB DinJ family
ATOBIA_N03850	COG1151	hydroxylamine reductase activity
ATOBIA_N03880	COG0477	Major facilitator Superfamily
ATOBIA_N03930	COG1827	regulation of RNA biosynthetic process
ATOBIA_N03940	COG0778	Nitroreductase
ATOBIA_N04000	COG0519	Catalyzes the synthesis of GMP from XMP
ATOBIA_N04050	COG4716	Myosin-crossreactive antigen
ATOBIA_N04080	COG1028	Short-chain dehydrogenase reductase Sdr
ATOBIA_N04130	COG0025	NhaP-type Na H and K H
ATOBIA_N04170	COG0789	Transcriptional regulator
ATOBIA_N04240	COG0024	Methionine aminopeptidase
ATOBIA_N04260	COG0765	amino acid transport
ATOBIA_N04270	COG1126	abc transporter atp-binding protein
ATOBIA_N04300	COG1316	TRANSCRIPTIONal
ATOBIA_N04330	COG2011	ABC-type metal ion transport system permease component
ATOBIA_N04340	COG1464	Belongs to the NlpA lipoprotein family
ATOBIA_N04350	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ATOBIA_N04360	COG3956	TIGRFAM MazG family protein
ATOBIA_N04380	COG0248	Ppx GppA phosphatase
ATOBIA_N04380	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ATOBIA_N04440	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ATOBIA_N04440	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ATOBIA_N04440	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ATOBIA_N04450	COG1105	Belongs to the carbohydrate kinase PfkB family
ATOBIA_N04480	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ATOBIA_N04490	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ATOBIA_N04510	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ATOBIA_N04520	COG0363	glucosamine-6-phosphate deaminase activity
ATOBIA_N04530	COG0006	proline dipeptidase activity
ATOBIA_N04550	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ATOBIA_N04590	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ATOBIA_N04620	COG1966	Carbon starvation protein
ATOBIA_N04630	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ATOBIA_N04650	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ATOBIA_N04670	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
ATOBIA_N04680	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ATOBIA_N04690	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ATOBIA_N04700	COG1045	serine acetyltransferase
ATOBIA_N04710	COG0215	cysteine-tRNA ligase activity
ATOBIA_N04720	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ATOBIA_N04740	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ATOBIA_N04750	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ATOBIA_N04770	COG0250	Participates in transcription elongation, termination and antitermination
ATOBIA_N04780	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ATOBIA_N04790	COG0081	regulation of translation
ATOBIA_N04800	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ATOBIA_N04810	COG0222	ribosome binding
ATOBIA_N04820	COG0085	RNA polymerase activity
ATOBIA_N04830	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ATOBIA_N04850	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ATOBIA_N04870	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ATOBIA_N04880	COG0051	transcription antitermination factor activity, RNA binding
ATOBIA_N04900	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ATOBIA_N04910	COG0088	Forms part of the polypeptide exit tunnel
ATOBIA_N04920	COG0089	rRNA binding
ATOBIA_N04930	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ATOBIA_N04940	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ATOBIA_N04950	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ATOBIA_N04960	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ATOBIA_N04980	COG0255	Belongs to the universal ribosomal protein uL29 family
ATOBIA_N04990	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ATOBIA_N05000	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ATOBIA_N05010	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ATOBIA_N05020	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ATOBIA_N05030	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ATOBIA_N05040	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ATOBIA_N05050	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ATOBIA_N05060	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ATOBIA_N05070	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ATOBIA_N05080	COG1841	ribosomal large subunit assembly
ATOBIA_N05090	COG0200	Binds to the 23S rRNA
ATOBIA_N05100	COG0201	protein transport
ATOBIA_N05110	COG0563	adenylate kinase activity
ATOBIA_N05150	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ATOBIA_N05160	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ATOBIA_N05170	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ATOBIA_N05190	COG0203	ribosomal protein L17
ATOBIA_N05220	COG0101	tRNA pseudouridine synthase activity
ATOBIA_N05250	COG1216	Glycosyl transferase, family 2
ATOBIA_N05270	COG0277	FAD linked oxidase domain protein
ATOBIA_N05280	COG2086	electron transfer activity
ATOBIA_N05290	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ATOBIA_N05320	COG1489	DNA binding
ATOBIA_N05330	COG0543	2 iron, 2 sulfur cluster binding
ATOBIA_N05340	COG0493	'glutamate synthase
ATOBIA_N05340	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ATOBIA_N05370	COG0193	aminoacyl-tRNA hydrolase activity
ATOBIA_N05390	COG1349	DNA-binding transcription factor activity
ATOBIA_N05410	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ATOBIA_N05420	COG1447	Phosphotransferase system cellobiose-specific component IIA
ATOBIA_N05450	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ATOBIA_N05460	COG2971	BadF BadG BcrA BcrD
ATOBIA_N05470	COG2723	6-phospho-beta-galactosidase activity
ATOBIA_N05480	COG1737	Transcriptional regulator
ATOBIA_N05490	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ATOBIA_N05500	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ATOBIA_N06080	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ATOBIA_N06110	COG1122	ATPase activity
ATOBIA_N06130	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
ATOBIA_N06180	COG0523	cobalamin synthesis protein
ATOBIA_N06200	COG2848	UPF0210 protein
ATOBIA_N06210	COG2755	lipolytic protein G-D-S-L family
ATOBIA_N06210	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ATOBIA_N06220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ATOBIA_N06260	COG0438	transferase activity, transferring glycosyl groups
ATOBIA_N06290	COG1842	Phage shock protein A
ATOBIA_N06300	COG2195	Cleaves the N-terminal amino acid of tripeptides
ATOBIA_N06370	COG3853	Toxic anion resistance protein (TelA)
ATOBIA_N06410	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ATOBIA_N06470	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ATOBIA_N06480	COG0505	Belongs to the CarA family
ATOBIA_N06490	COG0010	Belongs to the arginase family
ATOBIA_N06520	COG5002	protein histidine kinase activity
ATOBIA_N06540	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ATOBIA_N06550	COG0581	inorganic phosphate transmembrane transporter activity
ATOBIA_N06560	COG0573	inorganic phosphate transmembrane transporter activity
ATOBIA_N06590	COG1131	(ABC) transporter
ATOBIA_N06610	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ATOBIA_N06630	COG0446	pyridine nucleotide-disulphide oxidoreductase
ATOBIA_N06650	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ATOBIA_N06710	COG1957	nucleoside hydrolase
ATOBIA_N06730	COG0347	Belongs to the P(II) protein family
ATOBIA_N06740	COG0004	ammonium transporteR
ATOBIA_N06750	COG0716	FMN binding
ATOBIA_N06780	COG1254	Belongs to the acylphosphatase family
ATOBIA_N06790	COG1136	(ABC) transporter
ATOBIA_N06850	COG0720	synthase
ATOBIA_N06870	COG1216	Glycosyl transferase, family 2
ATOBIA_N06890	COG3830	Belongs to the UPF0237 family
ATOBIA_N06900	COG0372	Belongs to the citrate synthase family
ATOBIA_N06910	COG0561	phosphatase activity
ATOBIA_N06960	COG0745	RESPONSE REGULATOR receiver
ATOBIA_N06970	COG0745	RESPONSE REGULATOR receiver
ATOBIA_N07000	COG3158	transport of potassium into the cell
ATOBIA_N07030	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ATOBIA_N07030	COG0116	Belongs to the methyltransferase superfamily
ATOBIA_N07050	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ATOBIA_N07060	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ATOBIA_N07080	COG1438	arginine binding
ATOBIA_N07090	COG0137	argininosuccinate synthase activity
ATOBIA_N07100	COG0165	Argininosuccinate lyase
ATOBIA_N07110	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ATOBIA_N07130	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ATOBIA_N07140	COG0826	peptidase U32
ATOBIA_N07150	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ATOBIA_N07170	COG0717	Belongs to the dCTP deaminase family
ATOBIA_N07190	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ATOBIA_N07230	COG3103	Sh3 type 3 domain protein
ATOBIA_N07230	COG1388	LysM domain
ATOBIA_N07230	COG0791	NLP P60 protein
ATOBIA_N07250	COG0322	excinuclease ABC activity
ATOBIA_N07260	COG1660	Displays ATPase and GTPase activities
ATOBIA_N07270	COG1481	regulation of sporulation
ATOBIA_N07280	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ATOBIA_N07300	COG0149	triose-phosphate isomerase activity
ATOBIA_N07310	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ATOBIA_N07320	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ATOBIA_N07330	COG4166	transmembrane transport
ATOBIA_N07340	COG4166	transmembrane transport
ATOBIA_N07350	COG0601	transmembrane transport
ATOBIA_N07360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ATOBIA_N07370	COG0444	Belongs to the ABC transporter superfamily
ATOBIA_N07380	COG4608	Belongs to the ABC transporter superfamily
ATOBIA_N07420	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ATOBIA_N07460	COG1760	l-serine dehydratase
ATOBIA_N07470	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ATOBIA_N07500	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ATOBIA_N07510	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ATOBIA_N07520	COG0667	Aldo Keto reductase
ATOBIA_N07530	COG4115	mRNA cleavage
ATOBIA_N07610	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ATOBIA_N07670	COG0582	viral genome integration into host DNA
ATOBIA_N07730	COG0358	DNA primase activity
ATOBIA_N07760	COG0242	peptide deformylase activity
ATOBIA_N07770	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ATOBIA_N07800	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ATOBIA_N07830	COG0488	(ABC) transporter
ATOBIA_N07850	COG1994	Peptidase M50
ATOBIA_N07860	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ATOBIA_N07870	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ATOBIA_N07890	COG0588	phosphoglycerate mutase activity
ATOBIA_N07900	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ATOBIA_N07910	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ATOBIA_N07920	COG0750	zinc metalloprotease
ATOBIA_N07930	COG1160	GTP binding
ATOBIA_N07940	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ATOBIA_N07950	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ATOBIA_N07960	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ATOBIA_N07970	COG1104	cysteine desulfurase activity
ATOBIA_N07980	COG0482	sulfurtransferase activity
ATOBIA_N08010	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ATOBIA_N08020	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ATOBIA_N08030	COG0488	(ABC) transporter
ATOBIA_N08050	COG1132	(ABC) transporter
ATOBIA_N08070	COG1335	isochorismatase
ATOBIA_N08090	COG1611	Belongs to the LOG family
ATOBIA_N08150	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ATOBIA_N08190	COG1132	(ABC) transporter
ATOBIA_N08200	COG1302	Protein conserved in bacteria
ATOBIA_N08210	COG1461	Dihydroxyacetone kinase
ATOBIA_N08220	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ATOBIA_N08230	COG0742	ribosomal rna small subunit methyltransferase
ATOBIA_N08240	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ATOBIA_N08270	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ATOBIA_N08280	COG0416	fatty acid biosynthetic process
ATOBIA_N08290	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ATOBIA_N08330	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ATOBIA_N08410	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ATOBIA_N08420	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
ATOBIA_N08430	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ATOBIA_N08440	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ATOBIA_N08450	COG0564	pseudouridine synthase activity
ATOBIA_N08460	COG1215	transferase activity, transferring glycosyl groups
ATOBIA_N08470	COG0517	IMP dehydrogenase activity
ATOBIA_N08470	COG0516	GMP reductase activity
ATOBIA_N08480	COG0495	leucyl-tRNA aminoacylation
ATOBIA_N08500	COG0779	Required for maturation of 30S ribosomal subunits
ATOBIA_N08510	COG0195	Participates in both transcription termination and antitermination
ATOBIA_N08520	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ATOBIA_N08530	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ATOBIA_N08560	COG0196	riboflavin kinase activity
ATOBIA_N08580	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ATOBIA_N08610	COG1442	glycosyl transferase family 8
ATOBIA_N08610	COG1216	Glycosyl transferase, family 2
ATOBIA_N08620	COG1215	transferase activity, transferring glycosyl groups
ATOBIA_N08650	COG3842	ATPase activity
ATOBIA_N08660	COG1216	Glycosyl transferase, family 2
ATOBIA_N08660	COG0463	Glycosyl transferase, family 2
ATOBIA_N08670	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ATOBIA_N08680	COG0540	Belongs to the ATCase OTCase family
ATOBIA_N08690	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ATOBIA_N08700	COG0543	2 iron, 2 sulfur cluster binding
ATOBIA_N08710	COG0167	dihydroorotate dehydrogenase activity
ATOBIA_N08720	COG0284	orotidine-5'-phosphate decarboxylase activity
ATOBIA_N08730	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ATOBIA_N08750	COG0194	GDP metabolic process
ATOBIA_N08770	COG0301	tRNA thio-modification
ATOBIA_N08780	COG1555	photosystem II stabilization
ATOBIA_N08780	COG1596	polysaccharide export
ATOBIA_N08800	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ATOBIA_N08800	COG0321	lipoyl(octanoyl) transferase activity
ATOBIA_N08830	COG1686	Belongs to the peptidase S11 family
ATOBIA_N08850	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ATOBIA_N08860	COG0251	oxidation-reduction process
ATOBIA_N08890	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ATOBIA_N08900	COG0628	permease
ATOBIA_N08910	COG0371	Dehydrogenase
ATOBIA_N08960	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ATOBIA_N08970	COG1482	cell wall glycoprotein biosynthetic process
ATOBIA_N08980	COG2188	Transcriptional regulator
ATOBIA_N08990	COG0038	chloride channel
ATOBIA_N09010	COG0252	asparaginase activity
ATOBIA_N09020	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ATOBIA_N09040	COG1854	S-ribosylhomocysteine lyase activity
ATOBIA_N09070	COG1215	transferase activity, transferring glycosyl groups
ATOBIA_N09080	COG1116	anion transmembrane transporter activity
ATOBIA_N09090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ATOBIA_N09100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ATOBIA_N09120	COG1473	amidohydrolase
ATOBIA_N09180	COG0217	transcriptional regulatory protein
ATOBIA_N09280	COG3579	cysteine-type endopeptidase activity
ATOBIA_N09310	COG1739	Uncharacterized protein family UPF0029
ATOBIA_N09350	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
ATOBIA_N09360	COG1940	carbohydrate kinase activity
ATOBIA_N09370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ATOBIA_N09380	COG4608	Belongs to the ABC transporter superfamily
ATOBIA_N09410	COG0747	negative chemotaxis
ATOBIA_N09430	COG0140	phosphoribosyl-ATP diphosphatase activity
ATOBIA_N09450	COG0107	imidazoleglycerol-phosphate synthase activity
ATOBIA_N09460	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ATOBIA_N09470	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ATOBIA_N09480	COG0131	Imidazoleglycerol-phosphate dehydratase
ATOBIA_N09490	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ATOBIA_N09500	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ATOBIA_N09510	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ATOBIA_N09530	COG0411	ABC transporter
ATOBIA_N09580	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ATOBIA_N09590	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ATOBIA_N09610	COG1028	Short-chain dehydrogenase reductase Sdr
ATOBIA_N09630	COG2081	HI0933 family
ATOBIA_N09640	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
ATOBIA_N09660	COG0556	nucleotide-excision repair
ATOBIA_N09670	COG0739	heme binding
ATOBIA_N09670	COG0741	lytic transglycosylase activity
ATOBIA_N09670	COG1196	nuclear chromosome segregation
ATOBIA_N09710	COG2195	Cleaves the N-terminal amino acid of tripeptides
ATOBIA_N09720	COG0747	negative chemotaxis
ATOBIA_N09730	COG4608	Belongs to the ABC transporter superfamily
ATOBIA_N09740	COG0444	Belongs to the ABC transporter superfamily
ATOBIA_N09750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ATOBIA_N09760	COG0601	transmembrane transport
ATOBIA_N09770	COG4166	transmembrane transport
ATOBIA_N09800	COG1447	Phosphotransferase system cellobiose-specific component IIA
ATOBIA_N09820	COG0328	RNA-DNA hybrid ribonuclease activity
ATOBIA_N09830	COG1132	(ABC) transporter
ATOBIA_N09840	COG1362	aminopeptidase activity
ATOBIA_N09850	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ATOBIA_N09870	COG0544	peptidyl-prolyl cis-trans isomerase activity
ATOBIA_N09920	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ATOBIA_N09930	COG1597	lipid kinase activity
ATOBIA_N09950	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ATOBIA_N09960	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ATOBIA_N09970	COG1105	Belongs to the carbohydrate kinase PfkB family
ATOBIA_N09980	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ATOBIA_N09990	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ATOBIA_N09990	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ATOBIA_N10020	COG4120	Belongs to the binding-protein-dependent transport system permease family
ATOBIA_N10030	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ATOBIA_N10040	COG1620	l-lactate permease
ATOBIA_N10060	COG1971	Probably functions as a manganese efflux pump
ATOBIA_N10070	COG2270	Major facilitator Superfamily
ATOBIA_N10150	COG0436	Aminotransferase
ATOBIA_N10160	COG2365	Tyrosine phosphatase family
ATOBIA_N10190	COG2252	PERMEase
ATOBIA_N10200	COG0756	dUTP diphosphatase activity
ATOBIA_N10210	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ATOBIA_N10220	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ATOBIA_N10240	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ATOBIA_N10250	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ATOBIA_N10260	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ATOBIA_N10270	COG2359	stage V sporulation protein S
ATOBIA_N10290	COG1418	mRNA catabolic process
ATOBIA_N10300	COG2137	regulation of response to DNA damage stimulus
ATOBIA_N10310	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ATOBIA_N10330	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ATOBIA_N10340	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ATOBIA_N10350	COG1666	GTP binding
ATOBIA_N10380	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ATOBIA_N10390	COG1185	polyribonucleotide nucleotidyltransferase activity
ATOBIA_N10410	COG1381	Involved in DNA repair and RecF pathway recombination
ATOBIA_N10420	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ATOBIA_N10430	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ATOBIA_N10440	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ATOBIA_N10460	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ATOBIA_N10470	COG0484	heat shock protein binding
ATOBIA_N10480	COG0484	heat shock protein binding
ATOBIA_N10580	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ATOBIA_N10600	COG0481	GTPase activity
ATOBIA_N10610	COG0268	Binds directly to 16S ribosomal RNA
ATOBIA_N10670	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ATOBIA_N10730	COG0442	prolyl-tRNA aminoacylation
ATOBIA_N10740	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ATOBIA_N10750	COG0750	zinc metalloprotease
ATOBIA_N10760	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ATOBIA_N10770	COG4589	Belongs to the CDS family
ATOBIA_N10780	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ATOBIA_N10790	COG0233	cytoplasmic translational termination
ATOBIA_N10800	COG0528	UMP kinase activity
ATOBIA_N10820	COG0052	Belongs to the universal ribosomal protein uS2 family
ATOBIA_N10840	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
ATOBIA_N10860	COG0606	chelatase, subunit chli
ATOBIA_N10870	COG0792	nuclease activity
ATOBIA_N10880	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ATOBIA_N10890	COG0335	large ribosomal subunit rRNA binding
ATOBIA_N10900	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ATOBIA_N10900	COG0574	Belongs to the PEP-utilizing enzyme family
ATOBIA_N10910	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ATOBIA_N10920	COG0751	glycine-tRNA ligase activity
ATOBIA_N10930	COG0752	glycyl-tRNA synthetase alpha subunit
ATOBIA_N10940	COG0681	Belongs to the peptidase S26 family
ATOBIA_N10950	COG0336	Belongs to the RNA methyltransferase TrmD family
ATOBIA_N10980	COG0228	four-way junction DNA binding
ATOBIA_N10990	COG0745	RESPONSE REGULATOR receiver
ATOBIA_N11010	COG5002	protein histidine kinase activity
ATOBIA_N11020	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ATOBIA_N11030	COG0799	negative regulation of ribosome biogenesis
ATOBIA_N11050	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ATOBIA_N11060	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ATOBIA_N11070	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ATOBIA_N11080	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ATOBIA_N11090	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ATOBIA_N11100	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ATOBIA_N11140	COG0772	Belongs to the SEDS family
ATOBIA_N11150	COG0768	penicillin binding
ATOBIA_N11180	COG1077	Cell shape determining protein MreB Mrl
ATOBIA_N11200	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ATOBIA_N11220	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ATOBIA_N11230	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ATOBIA_N11240	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ATOBIA_N11250	COG0287	Prephenate dehydrogenase
ATOBIA_N11270	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ATOBIA_N11280	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ATOBIA_N11290	COG1605	Chorismate mutase
ATOBIA_N11290	COG0077	Prephenate dehydratase
ATOBIA_N11300	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ATOBIA_N11340	COG0602	queuosine metabolic process
ATOBIA_N11350	COG1328	CTP reductase activity
ATOBIA_N11360	COG0180	Tryptophanyl-tRNA synthetase
ATOBIA_N11370	COG1288	antiporter activity
ATOBIA_N11380	COG0436	Aminotransferase
ATOBIA_N11410	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ATOBIA_N11420	COG2235	arginine
ATOBIA_N11430	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ATOBIA_N11440	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ATOBIA_N11450	COG3191	aminopeptidase activity
ATOBIA_N11460	COG0424	maF-like protein
ATOBIA_N11490	COG0463	Glycosyl transferase, family 2
ATOBIA_N11510	COG0280	phosphate acetyltransferase
ATOBIA_N11520	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ATOBIA_N11540	COG1121	(ABC) transporter
ATOBIA_N11560	COG0673	inositol 2-dehydrogenase activity
ATOBIA_N11580	COG1482	cell wall glycoprotein biosynthetic process
ATOBIA_N11590	COG2188	Transcriptional regulator
ATOBIA_N11620	COG0537	adenosine 5'-monophosphoramidase activity
ATOBIA_N11630	COG1722	exodeoxyribonuclease VII activity
ATOBIA_N11650	COG2738	Putative neutral zinc metallopeptidase
ATOBIA_N11660	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ATOBIA_N11690	COG0778	Nitroreductase
ATOBIA_N11700	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ATOBIA_N11750	COG0762	integral membrane protein
ATOBIA_N11760	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ATOBIA_N11770	COG1799	cell septum assembly
ATOBIA_N11780	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ATOBIA_N11800	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ATOBIA_N11810	COG0573	inorganic phosphate transmembrane transporter activity
ATOBIA_N11820	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ATOBIA_N11840	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ATOBIA_N11860	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ATOBIA_N11870	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ATOBIA_N11880	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ATOBIA_N11890	COG0772	Belongs to the SEDS family
ATOBIA_N11900	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ATOBIA_N11910	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ATOBIA_N11920	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ATOBIA_N11950	COG0275	rRNA processing
ATOBIA_N11990	COG0504	CTP synthase activity
ATOBIA_N12010	COG0497	DNA recombination
ATOBIA_N12020	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ATOBIA_N12050	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ATOBIA_N12070	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ATOBIA_N12090	COG3716	PTS system mannose fructose sorbose family IID component
ATOBIA_N12100	COG3715	PTS system
ATOBIA_N12120	COG0006	proline dipeptidase activity
ATOBIA_N12140	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ATOBIA_N12160	COG0647	UMP catabolic process
ATOBIA_N12170	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ATOBIA_N12180	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ATOBIA_N12190	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ATOBIA_N12250	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ATOBIA_N12260	COG1297	OPT oligopeptide transporter protein
ATOBIA_N12280	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ATOBIA_N12320	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ATOBIA_N12320	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ATOBIA_N12320	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ATOBIA_N12330	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ATOBIA_N12360	COG0494	nUDIX hydrolase
ATOBIA_N12370	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ATOBIA_N12380	COG1959	2 iron, 2 sulfur cluster binding
ATOBIA_N12420	COG2827	Endonuclease containing a URI domain
ATOBIA_N12440	COG1454	alcohol dehydrogenase
ATOBIA_N12440	COG1012	belongs to the aldehyde dehydrogenase family
ATOBIA_N12500	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ATOBIA_N12580	COG4932	domain protein
ATOBIA_N12610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ATOBIA_N12650	COG1929	Belongs to the glycerate kinase type-1 family
ATOBIA_N12660	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ATOBIA_N12690	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ATOBIA_N12720	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ATOBIA_N12730	COG1447	Phosphotransferase system cellobiose-specific component IIA
ATOBIA_N12750	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ATOBIA_N12760	COG2723	6-phospho-beta-galactosidase activity
ATOBIA_N12770	COG2188	Transcriptional regulator
ATOBIA_N12780	COG1940	carbohydrate kinase activity
ATOBIA_N12800	COG2190	(PTS) system
ATOBIA_N12800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ATOBIA_N12800	COG1263	PTS System
ATOBIA_N12820	COG0525	valine-tRNA ligase activity
ATOBIA_N12850	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ATOBIA_N12860	COG0527	aspartate kinase activity
ATOBIA_N12870	COG0460	homoserine dehydrogenase
ATOBIA_N12890	COG0083	homoserine kinase activity
ATOBIA_N12960	COG0018	arginyl-trna synthetase
ATOBIA_N13020	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ATOBIA_N13030	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ATOBIA_N13080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ATOBIA_N13090	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ATOBIA_N13100	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ATOBIA_N13100	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ATOBIA_N13110	COG0343	queuine tRNA-ribosyltransferase activity
ATOBIA_N13140	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ATOBIA_N13160	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ATOBIA_N13160	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ATOBIA_N13180	COG1454	alcohol dehydrogenase
ATOBIA_N13190	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ATOBIA_N13220	COG0738	Major facilitator superfamily
ATOBIA_N13240	COG2721	sulfolactate sulfo-lyase activity
ATOBIA_N13280	COG1132	(ABC) transporter
ATOBIA_N13290	COG1132	(ABC) transporter
ATOBIA_N13300	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ATOBIA_N13320	COG1215	transferase activity, transferring glycosyl groups
ATOBIA_N13380	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ATOBIA_N13420	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ATOBIA_N13450	COG0640	Transcriptional regulator
ATOBIA_N13480	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ATOBIA_N13500	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ATOBIA_N13530	COG1278	Cold shock
ATOBIA_N13540	COG2759	Belongs to the formate--tetrahydrofolate ligase family
ATOBIA_N13560	COG2255	four-way junction helicase activity
ATOBIA_N13570	COG0632	four-way junction helicase activity
ATOBIA_N13590	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ATOBIA_N13590	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ATOBIA_N13600	COG2033	superoxide reductase activity
ATOBIA_N13660	COG0531	amino acid
ATOBIA_N13700	COG0587	DNA-directed DNA polymerase activity
ATOBIA_N13730	COG4496	protein, YerC YecD
ATOBIA_N13740	COG1950	PFAM Membrane protein of
ATOBIA_N13760	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ATOBIA_N13770	COG0154	amidase activity
ATOBIA_N13780	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ATOBIA_N13790	COG0148	phosphopyruvate hydratase activity
ATOBIA_N13830	COG0396	ATPase activity
ATOBIA_N13840	COG0719	Fe-S assembly protein
ATOBIA_N13860	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ATOBIA_N13870	COG0822	iron-sulfur transferase activity
ATOBIA_N13880	COG1959	2 iron, 2 sulfur cluster binding
ATOBIA_N13890	COG0791	NLP P60 protein
ATOBIA_N13890	COG1388	LysM domain
ATOBIA_N13890	COG3103	Sh3 type 3 domain protein
ATOBIA_N13930	COG0493	'glutamate synthase
ATOBIA_N13940	COG0070	glutamate synthase
ATOBIA_N13940	COG0069	glutamate synthase activity
ATOBIA_N13940	COG0067	glutamate synthase
ATOBIA_N13970	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ATOBIA_N13990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ATOBIA_N14000	COG0745	RESPONSE REGULATOR receiver
ATOBIA_N14020	COG0765	amino acid transport
ATOBIA_N14030	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
ATOBIA_N14040	COG0174	glutamine synthetase
ATOBIA_N14060	COG0588	phosphoglycerate mutase activity
ATOBIA_N14140	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ATOBIA_N14140	COG1918	ferrous iron import across plasma membrane
ATOBIA_N14150	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ATOBIA_N14150	COG1918	ferrous iron import across plasma membrane
ATOBIA_N14190	COG0546	phosphoglycolate phosphatase activity
ATOBIA_N14200	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ATOBIA_N14230	COG2235	arginine
ATOBIA_N14240	COG1288	antiporter activity
ATOBIA_N14250	COG2235	arginine
ATOBIA_N14260	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ATOBIA_N14290	COG1132	(ABC) transporter
ATOBIA_N14320	COG0564	pseudouridine synthase activity
ATOBIA_N14340	COG0124	histidyl-tRNA synthetase
ATOBIA_N14360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ATOBIA_N14370	COG0765	amino acid transport
ATOBIA_N14380	COG1126	abc transporter atp-binding protein
ATOBIA_N14410	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ATOBIA_N14550	COG3142	Participates in the control of copper homeostasis
ATOBIA_N14610	COG0473	3-isopropylmalate dehydrogenase activity
ATOBIA_N14640	COG2084	Dehydrogenase
ATOBIA_N14650	COG1307	EDD domain protein, DegV family
ATOBIA_N14660	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ATOBIA_N14680	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ATOBIA_N14690	COG0084	hydrolase, TatD family'
ATOBIA_N14700	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ATOBIA_N14710	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ATOBIA_N14710	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ATOBIA_N14720	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ATOBIA_N14870	COG1162	GTPase activity
ATOBIA_N14910	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ATOBIA_N15140	COG2188	Transcriptional regulator
ATOBIA_N15160	COG2731	YhcH YjgK YiaL family protein
ATOBIA_N15170	COG0072	phenylalanine-tRNA ligase activity
ATOBIA_N15180	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ATOBIA_N15190	COG1349	DNA-binding transcription factor activity
ATOBIA_N15200	COG2186	Transcriptional regulator
ATOBIA_N15210	COG2188	Transcriptional regulator
ATOBIA_N15230	COG1882	Formate acetyltransferase
ATOBIA_N15300	COG1105	Belongs to the carbohydrate kinase PfkB family
ATOBIA_N15350	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ATOBIA_N15440	COG1940	carbohydrate kinase activity
ATOBIA_N15450	COG1181	Belongs to the D-alanine--D-alanine ligase family
ATOBIA_N15460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ATOBIA_N15470	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
ATOBIA_N15480	COG1490	D-aminoacyl-tRNA deacylase activity
ATOBIA_N15530	COG0436	Aminotransferase
ATOBIA_N15550	COG0419	ATPase involved in DNA repair
ATOBIA_N15590	COG1970	mechanosensitive ion channel activity
ATOBIA_N15600	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ATOBIA_N15610	COG1735	metal-dependent hydrolase with the TIM-barrel fold
ATOBIA_N15620	COG4948	Mandelate Racemase Muconate Lactonizing
ATOBIA_N15630	COG3775	system Galactitol-specific IIC component
ATOBIA_N15640	COG3414	Phosphotransferase system galactitol-specific IIB component
ATOBIA_N15670	COG0674	pyruvate-flavodoxin oxidoreductase activity
ATOBIA_N15670	COG1013	pyruvate-flavodoxin oxidoreductase activity
ATOBIA_N15670	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ATOBIA_N15670	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ATOBIA_N15680	COG0038	chloride channel
ATOBIA_N15690	COG0679	Auxin Efflux Carrier
ATOBIA_N15700	COG0028	Belongs to the TPP enzyme family
ATOBIA_N15740	COG1136	(ABC) transporter
ATOBIA_N15850	COG1979	alcohol dehydrogenase
ATOBIA_N15880	COG3022	response to hydroperoxide
ATOBIA_N15920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ATOBIA_N15970	COG4555	ABC transporter
ATOBIA_N15980	COG0745	RESPONSE REGULATOR receiver
ATOBIA_N15990	COG5002	protein histidine kinase activity
ATOBIA_N16080	COG0205	6-phosphofructokinase activity
ATOBIA_N16120	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ATOBIA_N16150	COG0745	RESPONSE REGULATOR receiver
ATOBIA_N16180	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ATOBIA_N16240	COG1126	abc transporter atp-binding protein
ATOBIA_N16250	COG0765	amino acid transport
ATOBIA_N16310	COG1774	PSP1 C-terminal conserved region
ATOBIA_N16320	COG0470	DNA polymerase III
ATOBIA_N16330	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ATOBIA_N16350	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ATOBIA_N16360	COG0805	protein transport
ATOBIA_N16370	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ATOBIA_N16400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ATOBIA_N16430	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ATOBIA_N16440	COG1307	EDD domain protein, DegV family
ATOBIA_N16450	COG3177	Filamentation induced by cAMP protein fic
ATOBIA_N16510	COG0646	methionine synthase
ATOBIA_N16510	COG1410	methionine synthase
ATOBIA_N16540	COG1968	undecaprenyl-diphosphatase activity
ATOBIA_N16580	COG0697	spore germination
ATOBIA_N16630	COG1131	(ABC) transporter
ATOBIA_N16650	COG1012	belongs to the aldehyde dehydrogenase family
ATOBIA_N16700	COG0747	negative chemotaxis
ATOBIA_N16710	COG1253	flavin adenine dinucleotide binding
ATOBIA_N16730	COG0426	domain, Protein
ATOBIA_N16740	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ATOBIA_N16750	COG0205	6-phosphofructokinase activity
ATOBIA_N16780	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
ATOBIA_N16780	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
ATOBIA_N16790	COG1285	pathogenesis
ATOBIA_N16830	COG0039	L-malate dehydrogenase activity
ATOBIA_N16840	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ATOBIA_N16850	COG2205	protein histidine kinase activity
ATOBIA_N16890	COG0138	bifunctional purine biosynthesis protein purh
ATOBIA_N16910	COG0549	Belongs to the carbamate kinase family
ATOBIA_N16980	COG0438	transferase activity, transferring glycosyl groups
ATOBIA_N17010	COG1215	transferase activity, transferring glycosyl groups
ATOBIA_N17020	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ATOBIA_N17030	COG1088	dTDP-glucose 4,6-dehydratase activity
ATOBIA_N17070	COG1528	Iron-storage protein
ATOBIA_N17080	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ATOBIA_N17120	COG3620	sequence-specific DNA binding
ATOBIA_N17140	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ATOBIA_N17160	COG0515	serine threonine protein kinase
ATOBIA_N17160	COG2815	serine threonine protein kinase
ATOBIA_N17210	COG0515	serine threonine protein kinase
ATOBIA_N17210	COG2815	serine threonine protein kinase
ATOBIA_N17220	COG0488	(ABC) transporter
ATOBIA_N17260	COG2205	protein histidine kinase activity
ATOBIA_N17270	COG0745	RESPONSE REGULATOR receiver
ATOBIA_N17310	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ATOBIA_N17430	COG1199	ATP-dependent helicase activity
ATOBIA_N17440	COG1181	Belongs to the D-alanine--D-alanine ligase family
ATOBIA_N17470	COG1475	DNA binding
ATOBIA_N17480	COG1192	Involved in chromosome partitioning
ATOBIA_N17490	COG0357	Ribosomal RNA small subunit methyltransferase G
ATOBIA_N17500	COG1847	R3H domain protein
ATOBIA_N17510	COG0706	membrane insertase activity
ATOBIA_N17520	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ATOBIA_N17530	COG0594	ribonuclease P activity