locus-tag	class	description
Apar_0002	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
Apar_0003	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
Apar_0004	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
Apar_0006	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Apar_0007	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Apar_0010	ENOG4107RCV	ABC transporter, permease
Apar_0011	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Apar_0012	ENOG4108M60	Transcriptional regulator
Apar_0016	ENOG4105CI3	gtp-binding protein typa
Apar_0017	ENOG4107ZT3	family UPF0126
Apar_0019	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
Apar_0020	ENOG4108UUM	single-stranded DNA-binding protein
Apar_0021	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
Apar_0023	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
Apar_0024	ENOG4105CDU	Replicative dna helicase
Apar_0025	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
Apar_0027	ENOG4108YZ4	nudix hydrolase
Apar_0028	ENOG4105BZ1	(ABC) transporter
Apar_0030	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
Apar_0031	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
Apar_0032	ENOG4105KFN	sortase, SrtB family
Apar_0033	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
Apar_0034	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
Apar_0035	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
Apar_0041	ENOG4108W6C	Dehydrogenase
Apar_0043	ENOG4105CJ3	phosphate transporter
Apar_0053	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
Apar_0054	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
Apar_0057	ENOG4105DA5	(ABC) transporter
Apar_0059	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Apar_0060	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
Apar_0061	ENOG4105DCT	glycerol dehydrogenase
Apar_0063	ENOG4105CNW	domain protein
Apar_0069	ENOG4105CJW	magnesium transporter
Apar_0070	ENOG4108V0P	LemA family
Apar_0071	ENOG4108Z6B	deaminase
Apar_0072	ENOG4105DR4	Methyltransferase
Apar_0074	ENOG4105C1J	atp-dependent rna helicase
Apar_0075	ENOG4105CVG	Homoserine O-transsuccinylase
Apar_0076	ENOG4108RE9	Phosphodiesterase
Apar_0077	ENOG4108TZY	GntR Family Transcriptional Regulator
Apar_0078	ENOG4105CS2	ec 3.2.1.21
Apar_0079	ENOG4105CK1	PTS System
Apar_0080	ENOG4105VZJ	PTS System
Apar_0081	ENOG4105VCP	PTS System
Apar_0084	ENOG4105CU9	asparagine synthetase A
Apar_0085	ENOG4108WPJ	Ferritin-like domain
Apar_0090	ENOG4105F44	Two component transcriptional regulator, winged helix family
Apar_0091	ENOG4106F60	Histidine kinase
Apar_0092	ENOG4107T9Z	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
Apar_0094	ENOG4105CFG	Acts as a chaperone (By similarity)
Apar_0096	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Apar_0097	ENOG4105KNI	merR family transcriptional Regulator
Apar_0100	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Apar_0102	ENOG4105CNT	hydrolase family 2
Apar_0105	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
Apar_0106	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
Apar_0107	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
Apar_0108	ENOG4105CHM	Aminotransferase
Apar_0109	ENOG4107SSZ	Phosphatase
Apar_0110	ENOG4105CGK	Exodeoxyribonuclease III
Apar_0113	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
Apar_0114	ENOG41082DI	50s ribosomal protein l31
Apar_0115	ENOG4105C6E	dna polymerase iii
Apar_0116	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
Apar_0117	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
Apar_0121	ENOG4105CEN	a g-specific adenine glycosylase
Apar_0122	ENOG4108RAC	Rubrerythrin
Apar_0124	ENOG4108JA2	transcriptioN-repair coupling factor
Apar_0126	ENOG4105DXN	mazG family
Apar_0128	ENOG4105D49	3-dehydroquinate synthase
Apar_0130	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
Apar_0134	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
Apar_0135	ENOG41076CZ	activating enzyme
Apar_0136	ENOG4105G0K	glycine radical enzyme YjjI family
Apar_0139	ENOG4105DD7	kinase (PfkB family
Apar_0140	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
Apar_0141	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
Apar_0142	ENOG4105DIH	basic membrane
Apar_0143	ENOG4108JQ9	ABC transporter
Apar_0144	ENOG4105UIB	(ABC) transporter
Apar_0146	ENOG4105KG3	cytidine deaminase
Apar_0147	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
Apar_0151	ENOG4105K18	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity)
Apar_0152	ENOG4105DT3	PTS system, galactitol-specific IIc component
Apar_0155	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
Apar_0158	ENOG410667J	hydrolase
Apar_0163	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
Apar_0164	ENOG4108HVR	ABC transporter, permease
Apar_0165	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
Apar_0166	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
Apar_0167	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
Apar_0168	ENOG4105W42	Veg protein
Apar_0169	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
Apar_0172	ENOG4108HHA	Transketolase
Apar_0173	ENOG4108IUS	Transketolase
Apar_0174	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
Apar_0176	ENOG4105D85	methylase
Apar_0183	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
Apar_0184	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
Apar_0186	ENOG4105C3G	gtp-binding protein
Apar_0187	ENOG4108KGH	TRANSCRIPTIONal
Apar_0189	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Apar_0193	ENOG4105ESI	atpase involved in dna repair
Apar_0199	ENOG4105CVR	type I restriction-modification system
Apar_0208	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
Apar_0217	ENOG4105CJ1	ABC, transporter
Apar_0218	ENOG4107XNU	peptidase
Apar_0223	ENOG4105VXN	addiction module toxin, RelE StbE family
Apar_0224	ENOG410847I	Transcriptional regulator, BadM Rrf2 family
Apar_0226	ENOG4108RWI	nicotinamidase
Apar_0229	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Apar_0230	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Apar_0236	ENOG4107UUR	Chlorohydrolase aminohydrolase
Apar_0237	ENOG4105BZ8	glutamate synthase
Apar_0239	ENOG4107RCH	Diaminopropionate ammonia-lyase
Apar_0240	ENOG4107S4Y	M20 DapE family protein YgeY
Apar_0241	ENOG4105IW6	Carbamoyltransferase
Apar_0242	ENOG4105C5B	carbamate kinase
Apar_0243	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
Apar_0247	ENOG4105MJ6	selenium-dependent hydroxylase accessory protein YqeC
Apar_0249	ENOG4105C9B	Cysteine desulfurase
Apar_0251	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
Apar_0252	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
Apar_0253	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
Apar_0255	ENOG4105E0C	molybdate abc transporter
Apar_0256	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Apar_0261	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
Apar_0263	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
Apar_0272	ENOG4108JJ9	ABC, transporter
Apar_0273	ENOG4105BZ1	(ABC) transporter
Apar_0281	ENOG4105DIK	(ABC) transporter
Apar_0282	ENOG4105DSE	periplasmic solute binding protein
Apar_0283	ENOG4105CHR	reductase
Apar_0284	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
Apar_0285	ENOG410874W	AraC family transcriptional regulator
Apar_0289	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
Apar_0290	ENOG4105C59	p-type ATPase
Apar_0291	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
Apar_0292	ENOG4105DK2	UPF0207 protein
Apar_0293	ENOG4107QUY	Guanine deaminase
Apar_0294	ENOG4105CKI	cobalamin synthesis protein
Apar_0295	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
Apar_0298	ENOG4105EXC	Acyl-transferase
Apar_0301	ENOG41090A1	ferritin
Apar_0303	ENOG4105HDK	L-asparaginase
Apar_0306	ENOG4105DPH	UPF0371 protein
Apar_0312	ENOG4108IG5	Transcriptional regulator
Apar_0314	ENOG4105DG6	mannose-6-phosphate isomerase
Apar_0316	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
Apar_0317	ENOG4105CTD	carboxy-peptidase
Apar_0318	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
Apar_0319	ENOG4105CPF	Cell wall formation (By similarity)
Apar_0321	ENOG4105DM4	PTS System
Apar_0323	ENOG4105CDY	transcriptional regulatory protein
Apar_0324	ENOG4105N2W	Transcriptional regulator
Apar_0326	ENOG4105CZC	PTS system ascorbate-specific transporter subunit IIC
Apar_0331	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
Apar_0332	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
Apar_0333	ENOG4108HHA	Transketolase
Apar_0334	ENOG4108IUS	Transketolase
Apar_0336	ENOG4105BZ1	(ABC) transporter
Apar_0337	ENOG4105BZ8	glutamate synthase
Apar_0338	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
Apar_0339	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
Apar_0340	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
Apar_0342	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
Apar_0343	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
Apar_0344	ENOG4105F0V	Cell wall hydrolase
Apar_0345	ENOG4105EAH	synthase
Apar_0346	ENOG4105CMR	udp-glucose 4-epimerase
Apar_0348	ENOG4107R39	(ABC) transporter
Apar_0351	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
Apar_0352	ENOG4105BZ1	(ABC) transporter
Apar_0353	ENOG4105BZ1	(ABC) transporter
Apar_0355	ENOG4105D4A	Cell wall formation (By similarity)
Apar_0356	ENOG4105CTQ	phosphohexokinase
Apar_0357	ENOG4105CTQ	phosphohexokinase
Apar_0358	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
Apar_0360	ENOG4105EEM	helicase
Apar_0361	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
Apar_0363	ENOG4108RDQ	ABC transporter
Apar_0368	ENOG4105DUM	transcriptional regulator, lysR family
Apar_0375	ENOG4107QSE	Dipeptidase
Apar_0377	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Apar_0379	ENOG4108UZ3	Transporter
Apar_0382	ENOG4105C4R	Atp-dependent dna helicase
Apar_0384	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
Apar_0385	ENOG4107QXV	Phosphate transporter
Apar_0391	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
Apar_0393	ENOG4108IY8	ABC, transporter
Apar_0394	ENOG4105DFM	M18 family aminopeptidase
Apar_0396	ENOG4105D2N	Aldolase
Apar_0397	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
Apar_0398	ENOG4108UNV	SUF system FeS assembly protein, NifU family
Apar_0401	ENOG4105DIW	FeS assembly protein SUFB
Apar_0403	ENOG4105CUT	histidyl-tRNA synthetase
Apar_0405	ENOG4105DQ6	Transposase
Apar_0407	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Apar_0408	ENOG4105DFD	Na H antiporter
Apar_0409	ENOG4107RSM	transcriptional regulator
Apar_0413	ENOG410730G	Streptococcal surface antigen repeat
Apar_0414	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
Apar_0418	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
Apar_0420	ENOG4105C9M	aspartyl-trna synthetase
Apar_0421	ENOG4105BZ1	(ABC) transporter
Apar_0422	ENOG4105BZ1	(ABC) transporter
Apar_0423	ENOG4105WMR	Protein CrcB homolog
Apar_0424	ENOG41086D8	Transcriptional regulator
Apar_0425	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Apar_0426	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
Apar_0428	ENOG4105C5F	glutamine synthetase
Apar_0429	ENOG4107R0W	ABC transporter
Apar_0430	ENOG4105E5Q	amino acid AbC transporter
Apar_0432	ENOG4107NHD	transcriptional regulator
Apar_0433	ENOG4105C0H	protease
Apar_0434	ENOG4107QSV	RmuC domain protein
Apar_0435	ENOG4108IUW	ABC transporter
Apar_0438	ENOG4105VPX	protein, conserved in bacteria
Apar_0439	ENOG4105C59	p-type ATPase
Apar_0440	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
Apar_0441	ENOG4108KD5	ADP-ribosylation crystallin J1
Apar_0443	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
Apar_0445	ENOG4105EAD	ABC transporter
Apar_0446	ENOG4105DRP	amino acid AbC transporter
Apar_0447	ENOG4105CDA	abc transporter atp-binding protein
Apar_0448	ENOG4105EAB	amino acid AbC transporter
Apar_0449	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
Apar_0451	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
Apar_0455	ENOG4108N6D	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Apar_0457	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
Apar_0458	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
Apar_0460	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
Apar_0461	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
Apar_0463	ENOG4105DC7	peptidase M24
Apar_0465	ENOG4105ETZ	PTS System
Apar_0466	ENOG4105F3R	pts system mannose fructose sorbose family iid
Apar_0468	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
Apar_0470	ENOG410803B	Involved in the transcription termination process (By similarity)
Apar_0472	ENOG4105DX0	Hemolysin A
Apar_0473	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
Apar_0474	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
Apar_0475	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
Apar_0476	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Apar_0477	ENOG4108V6E	Cell division protein mraZ
Apar_0478	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
Apar_0480	ENOG4105CJN	penicillin-binding protein
Apar_0481	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
Apar_0482	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
Apar_0483	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
Apar_0484	ENOG4105CNI	cell division protein FtsW
Apar_0485	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
Apar_0486	ENOG4105DFU	Cell wall formation (By similarity)
Apar_0487	ENOG4105D4A	Cell wall formation (By similarity)
Apar_0488	ENOG4105ME9	cell division protein FtsQ
Apar_0489	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
Apar_0491	ENOG4105DFA	alanine racemase domain protein
Apar_0492	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
Apar_0493	ENOG41067XK	integral membrane protein
Apar_0497	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
Apar_0498	ENOG4105ECB	domain protein
Apar_0498	ENOG4105ECB	domain protein
Apar_0501	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
Apar_0503	ENOG4105EJQ	L-serine dehydratase
Apar_0504	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
Apar_0506	ENOG4105DFM	M18 family aminopeptidase
Apar_0508	ENOG4105BZ1	(ABC) transporter
Apar_0513	ENOG4105CHM	Aminotransferase
Apar_0515	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
Apar_0516	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
Apar_0518	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
Apar_0519	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
Apar_0520	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
Apar_0521	ENOG4105C5X	domain protein
Apar_0522	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
Apar_0523	ENOG4105VJV	50s ribosomal protein L35
Apar_0524	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
Apar_0525	ENOG4105ESV	Glycosyl transferase, family 4
Apar_0528	ENOG4105DAP	Nicotinate phosphoribosyltransferase
Apar_0529	ENOG4105C75	arginyL-tRNA synthetase
Apar_0534	ENOG4105C32	Amino acid ABC transporter (Permease)
Apar_0535	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
Apar_0536	ENOG4105C0Z	ABC transporter
Apar_0537	ENOG4108IV0	ABC, transporter
Apar_0538	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
Apar_0539	ENOG4105D98	threonine synthase
Apar_0540	ENOG4105D6E	homoserine dehydrogenase
Apar_0541	ENOG4105CFH	Aspartokinase
Apar_0542	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
Apar_0549	ENOG41083X2	DNA polymerase III, epsilon subunit
Apar_0551	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
Apar_0567	ENOG4105EYG	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity)
Apar_0598	ENOG4105C87	Aminotransferase class I and II
Apar_0599	ENOG4105DE4	1-phosphofructokinase
Apar_0601	ENOG4105CBD	Diacylglycerol kinase
Apar_0608	ENOG4107SBB	4-alpha-glucanotransferase (EC 2.4.1.25)
Apar_0609	ENOG4108IUN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
Apar_0610	ENOG4105D82	Glutamate dehydrogenase
Apar_0611	ENOG4108VX5	3-methyladenine DNA glycosylase
Apar_0612	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
Apar_0613	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
Apar_0614	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
Apar_0615	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
Apar_0616	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
Apar_0619	ENOG4105CUZ	uba thif-type nad fad binding protein
Apar_0620	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
Apar_0621	ENOG4105CKU	formyltetrahydrofolate synthetase
Apar_0623	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
Apar_0624	ENOG4105EUJ	GTP cyclohydrolase i
Apar_0625	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
Apar_0627	ENOG4105C22	threonyL-tRNA synthetase
Apar_0628	ENOG4105C28	cystathionine
Apar_0629	ENOG4108EKI	Dehydrogenase
Apar_0632	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
Apar_0638	ENOG4106ZEE	Diacylglycerol kinase
Apar_0639	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
Apar_0641	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
Apar_0643	ENOG4105K59	histidine triad (HIT) protein
Apar_0644	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
Apar_0646	ENOG4108IJ2	phosphate acetyltransferase
Apar_0647	ENOG4107R6R	udp-galactopyranose mutase
Apar_0652	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
Apar_0653	ENOG4105C31	Tryptophanyl-tRNA synthetase
Apar_0654	ENOG4105F1A	Pyruvate formate-lyase
Apar_0655	ENOG4105C6N	Formate acetyltransferase
Apar_0658	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
Apar_0659	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
Apar_0660	ENOG4105E2X	shikimate dehydrogenase
Apar_0662	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
Apar_0664	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
Apar_0665	ENOG4105D49	3-dehydroquinate synthase
Apar_0666	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
Apar_0668	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
Apar_0670	ENOG4105DFF	Rod shape-determining protein mreb
Apar_0673	ENOG4107RF6	penicillin-binding protein
Apar_0674	ENOG4105CNI	cell division protein FtsW
Apar_0678	ENOG410826X	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
Apar_0679	ENOG4105K46	50S ribosomal protein l27
Apar_0681	ENOG4108JJB	ABC transporter
Apar_0682	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
Apar_0683	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Apar_0684	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
Apar_0685	ENOG4108WF2	Metal Dependent Phosphohydrolase
Apar_0686	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
Apar_0689	ENOG4105VB6	UPF0109 protein
Apar_0690	ENOG41082N4	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
Apar_0691	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
Apar_0693	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
Apar_0694	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
Apar_0695	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
Apar_0696	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
Apar_0697	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
Apar_0698	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
Apar_0699	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Apar_0700	ENOG4105VFF	UPF0102 protein
Apar_0701	ENOG4105C0P	Mg chelatase subunit ChlI
Apar_0703	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
Apar_0704	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Apar_0705	ENOG4105CE9	30S ribosomal protein S2
Apar_0706	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
Apar_0708	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
Apar_0709	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
Apar_0710	ENOG4105KNE	Phosphatidate cytidylyltransferase
Apar_0711	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
Apar_0712	ENOG4105DZP	Membrane-associated zinc metalloprotease
Apar_0713	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
Apar_0714	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
Apar_0719	ENOG4105C5H	ABC transporter
Apar_0720	ENOG4108Z4T	Peptidase M50
Apar_0721	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
Apar_0722	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
Apar_0723	ENOG4105FE9	pseudouridine synthase
Apar_0724	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
Apar_0726	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
Apar_0728	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
Apar_0729	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
Apar_0730	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
Apar_0731	ENOG4105DJV	ribulose-phosphate 3-epimerase
Apar_0734	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
Apar_0736	ENOG4105C5H	ABC transporter
Apar_0737	ENOG4105BZ1	(ABC) transporter
Apar_0738	ENOG4105BZ1	(ABC) transporter
Apar_0740	ENOG4105E0X	reductase
Apar_0742	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
Apar_0743	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
Apar_0744	ENOG4105DVA	methyltransferase
Apar_0745	ENOG4105CCI	Myosin-Cross-Reactive Antigen
Apar_0746	ENOG4108I0C	methyltransferase
Apar_0747	ENOG4108HCJ	Hydrolase
Apar_0750	ENOG4105DZ1	carboxypeptidase
Apar_0752	ENOG4105KME	endoribonuclease L-psp
Apar_0755	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
Apar_0759	ENOG4105RHY	Pfam:UPF0157
Apar_0760	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
Apar_0761	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Apar_0766	ENOG4105C7N	Xanthine uracil vitamin C permease
Apar_0767	ENOG4107ZFB	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
Apar_0768	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
Apar_0770	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
Apar_0772	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
Apar_0773	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
Apar_0774	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Apar_0775	ENOG4105MCT	stage V sporulation protein S
Apar_0777	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
Apar_0778	ENOG4105Y3E	Modulates RecA activity (By similarity)
Apar_0779	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
Apar_0781	ENOG4108I62	cina-like protein
Apar_0782	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
Apar_0783	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
Apar_0784	ENOG4108VPT	UPF0234 protein
Apar_0786	ENOG4107QZI	cell division protein FtsK
Apar_0787	ENOG4105CN5	Metallo-Beta-Lactamase
Apar_0788	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
Apar_0789	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
Apar_0791	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
Apar_0792	ENOG4107YR5	Diacylglycerol kinase
Apar_0795	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Apar_0796	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Apar_0797	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Apar_0799	ENOG4105CSA	Coproporphyrinogen iii oxidase
Apar_0801	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
Apar_0802	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
Apar_0804	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
Apar_0805	ENOG4105KQC	Competence protein
Apar_0806	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
Apar_0808	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
Apar_0810	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
Apar_0811	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
Apar_0812	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
Apar_0813	ENOG4105CD3	dihydroorotase
Apar_0814	ENOG4105CXT	aspartate transcarbamylase
Apar_0815	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
Apar_0817	ENOG4105ETE	Transcriptional regulator (LacI family
Apar_0818	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
Apar_0820	ENOG4105CKN	UDP-glucose-hexose-1-phosphate uridylyltransferase
Apar_0821	ENOG4107R2W	ABC transporter, permease
Apar_0822	ENOG4105C2J	ABC transporter
Apar_0823	ENOG4105EMA	Periplasmic binding protein LacI transcriptional regulator
Apar_0824	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Apar_0826	ENOG4105DTN	riboflavin biosynthesis protein ribF
Apar_0827	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
Apar_0829	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
Apar_0830	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
Apar_0831	ENOG4105CHV	Transcription elongation factor NusA
Apar_0832	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
Apar_0833	ENOG4105C8T	Leucyl-tRNA synthetase
Apar_0834	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Apar_0838	ENOG4108NKV	transcriptional regulator
Apar_0839	ENOG4105C34	Pseudouridine synthase
Apar_0841	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
Apar_0842	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Apar_0843	ENOG4105C2N	RNA methyltransferase TrmH family group 3
Apar_0844	ENOG41067QW	Transcriptional regulator
Apar_0848	ENOG4105WD1	Membrane
Apar_0851	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
Apar_0852	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
Apar_0853	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
Apar_0854	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
Apar_0855	ENOG41085YX	50S ribosomal protein L32
Apar_0858	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
Apar_0861	ENOG4105DP4	dak2 domain fusion protein ylov
Apar_0862	ENOG4108ZAA	Alkaline-shock protein
Apar_0863	ENOG4105VB9	50S ribosomal protein l28
Apar_0866	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
Apar_0867	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
Apar_0869	ENOG4105C25	Primosomal protein n'
Apar_0872	ENOG4105D1Q	UPF0246 protein
Apar_0875	ENOG41082T9	Membrane
Apar_0876	ENOG4105KRI	phosphocarrier protein (HPr
Apar_0878	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
Apar_0879	ENOG4105WPN	DNA integration recombination invertion protein
Apar_0881	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
Apar_0884	ENOG4105BZ1	(ABC) transporter
Apar_0885	ENOG4105BZ1	(ABC) transporter
Apar_0886	ENOG4108YZS	Had-superfamily hydrolase, subfamily ia, variant 1
Apar_0891	ENOG4105S7A	ErfK ybiS ycfS ynhG family protein
Apar_0893	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
Apar_0894	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
Apar_0895	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
Apar_0897	ENOG4105MAX	Superoxide reductase
Apar_0898	ENOG4105C0B	DNA polymerase III (alpha subunit)
Apar_0899	ENOG4105CTZ	aminopeptidase c
Apar_0903	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
Apar_0904	ENOG4105C5Y	PTS System
Apar_0908	ENOG4105D3R	alkyl hydroperoxide reductase
Apar_0912	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
Apar_0913	ENOG4105C3J	Cysteine desulfurase
Apar_0915	ENOG41082AN	stage II sporulation protein
Apar_0923	ENOG4105BZA	Phosphoglycerate kinase
Apar_0925	ENOG4105CIE	May be required for sporulation (By similarity)
Apar_0926	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
Apar_0927	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
Apar_0929	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
Apar_0932	ENOG4108JQ7	(ABC) transporter
Apar_0935	ENOG4105DEF	Extracellular solute-binding protein, family 5
Apar_0938	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
Apar_0939	ENOG4105CJR	Integral membrane protein (MviN
Apar_0940	ENOG4108Z66	YbaK ebsC protein
Apar_0941	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
Apar_0942	ENOG4108R66	Conserved Protein
Apar_0945	ENOG4105DZ0	fad dependent oxidoreductase
Apar_0946	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
Apar_0948	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
Apar_0949	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Apar_0953	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
Apar_0955	ENOG4105DEF	Extracellular solute-binding protein, family 5
Apar_0956	ENOG4108JQ7	(ABC) transporter
Apar_0957	ENOG4105C3U	ABC transporter
Apar_0958	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Apar_0959	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
Apar_0960	ENOG4105DEF	Extracellular solute-binding protein, family 5
Apar_0964	ENOG4108Z29	Flavodoxin
Apar_0969	ENOG4105K56	Transcriptional regulator
Apar_0972	ENOG4105CE1	Ferrous iron transport protein b
Apar_0974	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
Apar_0981	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
Apar_0982	ENOG4105EPR	degv family
Apar_0985	ENOG4105MJ2	Competence protein
Apar_0993	ENOG4105DHP	deoxycytidine triphosphate deaminase
Apar_0994	ENOG41083MR	nifu domain-containing protein
Apar_0995	ENOG4105CFP	Peptidase U32
Apar_0996	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
Apar_0997	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
Apar_1000	ENOG4105KPE	licD family
Apar_1004	ENOG4105KPE	licD family
Apar_1005	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
Apar_1006	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
Apar_1007	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
Apar_1009	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
Apar_1010	ENOG4105BZ4	penicillin-binding protein
Apar_1011	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
Apar_1014	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
Apar_1015	ENOG4105DFH	Transport of potassium into the cell (By similarity)
Apar_1016	ENOG4108AZI	Catalyzes the hydrolysis of 4-amino-2-methyl-5- hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2- methyl-5-hydroxymethylpyrimidine phosphate (HMP-P) (By similarity)
Apar_1017	ENOG4105VUC	UPF0237 protein
Apar_1019	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
Apar_1035	ENOG4107U53	septum site-determining protein minD
Apar_1037	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
Apar_1039	ENOG4105C5I	Dehydrogenase
Apar_1041	ENOG4105BZ1	(ABC) transporter
Apar_1044	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Apar_1045	ENOG41062D9	Histidine kinase
Apar_1047	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
Apar_1049	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
Apar_1051	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
Apar_1052	ENOG4105DCT	glycerol dehydrogenase
Apar_1054	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
Apar_1055	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
Apar_1057	ENOG4105DIK	(ABC) transporter
Apar_1058	ENOG4105DSE	periplasmic solute binding protein
Apar_1059	ENOG4108QG2	Membrane
Apar_1061	ENOG4105CE4	GlcNAc 6-P deacetylase
Apar_1062	ENOG4105E70	isomerase
Apar_1063	ENOG4105FDP	GntR family transcriptional regulator
Apar_1064	ENOG4105F3R	pts system mannose fructose sorbose family iid
Apar_1065	ENOG4105ETZ	PTS System
Apar_1066	ENOG4108RG5	PTS system N-acetylgalactosamine-specific transporter subunit IIB
Apar_1067	ENOG4105VIE	preprotein translocase, subunit YajC
Apar_1070	ENOG4105D2N	Aldolase
Apar_1071	ENOG4105CM2	brancheD-chain amino acid aminotransferase
Apar_1072	ENOG4105K78	MarR family Transcriptional regulator
Apar_1077	ENOG4105C5Y	PTS System
Apar_1079	ENOG4105C19	ABC transporter
Apar_1084	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
Apar_1085	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
Apar_1089	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
Apar_1090	ENOG4105MA4	psp1 domain protein
Apar_1091	ENOG4107QMP	dna polymerase iii subunits gamma and tau
Apar_1092	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
Apar_1093	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
Apar_1094	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
Apar_1095	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
Apar_1096	ENOG4105WN5	stage II sporulation protein
Apar_1098	ENOG4105XT2	Transcriptional regulator
Apar_1103	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Apar_1104	ENOG4105C2M	dna polymerase I
Apar_1107	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
Apar_1109	ENOG41080E8	Transcriptional regulator, Spx MgsR family
Apar_1117	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
Apar_1120	ENOG4107QW4	alcohol dehydrogenase
Apar_1121	ENOG4105EPR	degv family
Apar_1124	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
Apar_1126	ENOG4105K64	Glycosyl transferase, family 2
Apar_1129	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
Apar_1130	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
Apar_1131	ENOG4108JJB	ABC transporter
Apar_1132	ENOG4108ZT0	50S ribosomal protein l17
Apar_1133	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Apar_1134	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
Apar_1135	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
Apar_1136	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Apar_1137	ENOG41067V7	50S ribosomal protein L36
Apar_1138	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
Apar_1140	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
Apar_1142	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
Apar_1143	ENOG4105VPB	50S ribosomal protein L30
Apar_1144	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
Apar_1145	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
Apar_1147	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
Apar_1150	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
Apar_1151	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
Apar_1152	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
Apar_1153	ENOG41082SA	50s ribosomal protein l29
Apar_1154	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
Apar_1155	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
Apar_1156	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
Apar_1157	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
Apar_1158	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Apar_1159	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
Apar_1160	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
Apar_1161	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
Apar_1163	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
Apar_1164	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Apar_1165	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
Apar_1166	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
Apar_1168	ENOG41066UM	arsR family transcriptional regulator
Apar_1169	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Apar_1170	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Apar_1171	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
Apar_1172	ENOG4108VZM	50s ribosomal protein L10
Apar_1173	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
Apar_1174	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
Apar_1175	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
Apar_1177	ENOG4105WDJ	50S ribosomal protein L33
Apar_1178	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Apar_1180	ENOG4105C2N	RNA methyltransferase TrmH family group 3
Apar_1181	ENOG4105C8N	cysteinyl-tRNA synthetase
Apar_1182	ENOG4105BZ1	(ABC) transporter
Apar_1183	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
Apar_1184	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
Apar_1185	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
Apar_1187	ENOG4105CRK	lysyL-tRNA synthetase
Apar_1188	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
Apar_1189	ENOG41063NY	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
Apar_1191	ENOG4105C6K	Malic enzyme
Apar_1193	ENOG4108RVA	ribokinase
Apar_1194	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
Apar_1196	ENOG4108RCM	Nitroreductase
Apar_1199	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
Apar_1200	ENOG4106KNT	transcriptional regulator
Apar_1203	ENOG4108ZGC	gaf domain protein
Apar_1205	ENOG4105DPN	Oligoendopeptidase f
Apar_1213	ENOG4107SQC	5-methylcytosine-specific restriction enzyme subunit McrC
Apar_1218	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
Apar_1220	ENOG4105ETE	Transcriptional regulator (LacI family
Apar_1221	ENOG4105CAG	UPF0210 protein
Apar_1224	ENOG4105CVR	type I restriction-modification system
Apar_1230	ENOG4107SUZ	Sodium/hydrogen exchanger family
Apar_1235	ENOG4105US7	Histidine kinase
Apar_1236	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
Apar_1243	ENOG4105K8N	protein family UPF0079, ATPase
Apar_1244	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
Apar_1245	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
Apar_1246	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
Apar_1247	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
Apar_1248	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
Apar_1250	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
Apar_1252	ENOG4105DE4	1-phosphofructokinase
Apar_1254	ENOG4108IMY	Transcriptional regulator
Apar_1256	ENOG4105CK1	PTS System
Apar_1257	ENOG4105VZJ	PTS System
Apar_1258	ENOG4105D7K	pfkb domain protein
Apar_1267	ENOG4105U3E	Transcriptional regulator
Apar_1268	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
Apar_1272	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
Apar_1274	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
Apar_1275	ENOG4107QUY	Guanine deaminase
Apar_1277	ENOG4108MP6	LysR family Transcriptional regulator
Apar_1278	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
Apar_1279	ENOG4105CAK	Cell division ATP-binding protein ftsE
Apar_1281	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
Apar_1282	ENOG4105C2X	Arabinose 5-phosphate isomerase
Apar_1287	ENOG410804X	Transcriptional regulator
Apar_1289	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
Apar_1290	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
Apar_1292	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
Apar_1293	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
Apar_1295	ENOG4108KGH	TRANSCRIPTIONal
Apar_1296	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
Apar_1298	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
Apar_1299	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
Apar_1300	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
Apar_1301	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Apar_1302	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
Apar_1303	ENOG4105VH4	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Apar_1304	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
Apar_1307	ENOG4108YZG	isomerase
Apar_1309	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
Apar_1310	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
Apar_1312	ENOG4105DQR	SNARE associated Golgi
Apar_1314	ENOG4105F3R	pts system mannose fructose sorbose family iid
Apar_1315	ENOG4105ETZ	PTS System
Apar_1318	ENOG4107QP8	phosphohexose isomerase
Apar_1320	ENOG4105K63	Thioredoxin
Apar_1321	ENOG410841Q	phosphoesterase PA-phosphatase related protein
Apar_1323	ENOG4105DY9	regulatoR
Apar_1324	ENOG4108HRK	Histidine kinase
Apar_1330	ENOG4105DC1	bifunctional purine biosynthesis protein purh
Apar_1332	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
Apar_1333	ENOG4105GR3	Histidine kinase
Apar_1335	ENOG4105C5Y	PTS System
Apar_1336	ENOG4105CG3	alpha amylase, catalytic region
Apar_1338	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
Apar_1340	ENOG4105D9P	serine threonine protein kinase
Apar_1341	ENOG4105IDI	abc transporter atp-binding protein
Apar_1343	ENOG4108ZF3	Phosphatase
Apar_1345	ENOG4105D9P	serine threonine protein kinase
Apar_1347	ENOG4105C8V	SAICAR synthetase
Apar_1348	ENOG4105BZU	Histidine kinase
Apar_1349	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Apar_1351	ENOG4105C83	adenylosuccinate lyase
Apar_1359	ENOG4105DVT	helicase
Apar_1360	ENOG4105CPF	Cell wall formation (By similarity)
Apar_1361	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
Apar_1362	ENOG4105FA0	parb-like partition protein
Apar_1363	ENOG4107QJE	Chromosome Partitioning Protein
Apar_1364	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
Apar_1366	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
Apar_1367	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
Apar_1368	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)