locus-tag	class	description
Apar_0002	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Apar_0003	COG0592	DNA-directed DNA polymerase activity
Apar_0004	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Apar_0006	COG0187	DNA topoisomerase II activity
Apar_0007	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Apar_0011	COG3842	ATPase activity
Apar_0012	COG1609	Transcriptional regulator
Apar_0017	COG2860	membrane
Apar_0019	COG0360	Binds together with S18 to 16S ribosomal RNA
Apar_0020	COG0629	single-stranded DNA binding
Apar_0021	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Apar_0023	COG0359	binds to the 23S rRNA
Apar_0024	COG0305	Participates in initiation and elongation during chromosome replication
Apar_0025	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Apar_0027	COG0494	nUDIX hydrolase
Apar_0028	COG1132	(ABC) transporter
Apar_0030	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
Apar_0031	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Apar_0032	COG4509	Sortase family
Apar_0033	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Apar_0034	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Apar_0035	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Apar_0041	COG0300	oxidoreductase activity
Apar_0043	COG0306	phosphate transporter
Apar_0053	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Apar_0054	COG0039	L-malate dehydrogenase activity
Apar_0057	COG1131	(ABC) transporter
Apar_0059	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Apar_0060	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Apar_0061	COG0371	Dehydrogenase
Apar_0063	COG0426	domain, Protein
Apar_0069	COG2239	Acts as a magnesium transporter
Apar_0070	COG1704	LemA family
Apar_0071	COG0590	tRNA wobble adenosine to inosine editing
Apar_0072	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Apar_0074	COG0513	Belongs to the DEAD box helicase family
Apar_0076	COG0622	Phosphoesterase
Apar_0077	COG2188	Transcriptional regulator
Apar_0078	COG2723	6-phospho-beta-galactosidase activity
Apar_0079	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Apar_0080	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Apar_0081	COG1447	Phosphotransferase system cellobiose-specific component IIA
Apar_0084	COG2502	aspartate--ammonia ligase
Apar_0085	COG0783	Belongs to the Dps family
Apar_0088	COG0348	domain, Protein
Apar_0090	COG0745	RESPONSE REGULATOR receiver
Apar_0091	COG2205	protein histidine kinase activity
Apar_0094	COG0443	Heat shock 70 kDa protein
Apar_0096	COG0484	heat shock protein binding
Apar_0097	COG0789	Transcriptional regulator
Apar_0100	COG0542	response to heat
Apar_0102	COG3250	beta-galactosidase activity
Apar_0105	COG1234	tRNA 3'-trailer cleavage
Apar_0106	COG0037	tRNA processing
Apar_0108	COG0436	Aminotransferase
Apar_0109	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Apar_0110	COG0708	Exodeoxyribonuclease III
Apar_0113	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Apar_0114	COG0254	rRNA binding
Apar_0115	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Apar_0116	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Apar_0117	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Apar_0120	COG1959	2 iron, 2 sulfur cluster binding
Apar_0121	COG1194	a g-specific adenine glycosylase
Apar_0122	COG1592	Rubrerythrin
Apar_0123	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Apar_0124	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Apar_0126	COG3956	TIGRFAM MazG family protein
Apar_0128	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Apar_0128	COG0248	Ppx GppA phosphatase
Apar_0129	COG3959	Transketolase, thiamine diphosphate binding domain
Apar_0130	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Apar_0134	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
Apar_0135	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Apar_0136	COG1328	CTP reductase activity
Apar_0139	COG1522	sequence-specific DNA binding
Apar_0139	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Apar_0140	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
Apar_0141	COG0813	purine-nucleoside phosphorylase activity
Apar_0146	COG0295	cytidine deaminase activity
Apar_0147	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
Apar_0151	COG3414	Phosphotransferase system galactitol-specific IIB component
Apar_0152	COG3775	system Galactitol-specific IIC component
Apar_0155	COG2195	Cleaves the N-terminal amino acid of tripeptides
Apar_0158	COG0561	phosphatase activity
Apar_0163	COG0644	oxidoreductase
Apar_0164	COG0577	efflux transmembrane transporter activity
Apar_0166	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Apar_0167	COG0363	glucosamine-6-phosphate deaminase activity
Apar_0168	COG4466	Protein conserved in bacteria
Apar_0169	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Apar_0172	COG3959	Transketolase, thiamine diphosphate binding domain
Apar_0173	COG3958	Transketolase
Apar_0174	COG1250	3-hydroxyacyl-CoA dehydrogenase
Apar_0176	COG1002	Type II restriction enzyme, methylase subunits
Apar_0183	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Apar_0184	COG0459	protein refolding
Apar_0187	COG1316	TRANSCRIPTIONal
Apar_0188	COG1388	LysM domain
Apar_0188	COG4932	domain protein
Apar_0189	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Apar_0189	COG0519	Catalyzes the synthesis of GMP from XMP
Apar_0193	COG1196	nuclear chromosome segregation
Apar_0199	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
Apar_0207	COG3177	Filamentation induced by cAMP protein fic
Apar_0217	COG1131	(ABC) transporter
Apar_0223	COG3041	Addiction module toxin RelE StbE family
Apar_0224	COG1959	2 iron, 2 sulfur cluster binding
Apar_0226	COG1335	isochorismatase
Apar_0229	COG1136	(ABC) transporter
Apar_0230	COG1136	(ABC) transporter
Apar_0230	COG0577	efflux transmembrane transporter activity
Apar_0236	COG0402	S-adenosylhomocysteine deaminase activity
Apar_0237	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Apar_0237	COG0493	'glutamate synthase
Apar_0240	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Apar_0241	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Apar_0242	COG0549	Belongs to the carbamate kinase family
Apar_0243	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Apar_0243	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Apar_0245	COG0251	oxidation-reduction process
Apar_0247	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Apar_0249	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Apar_0251	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
Apar_0251	COG3608	succinylglutamate desuccinylase aspartoacylase
Apar_0252	COG0709	Synthesizes selenophosphate from selenide and ATP
Apar_0253	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
Apar_0253	COG3608	succinylglutamate desuccinylase aspartoacylase
Apar_0255	COG4149	molybdate abc transporter
Apar_0256	COG3842	ATPase activity
Apar_0261	COG0521	Mo-molybdopterin cofactor biosynthetic process
Apar_0263	COG3976	FMN-binding domain protein
Apar_0263	COG1053	succinate dehydrogenase
Apar_0263	COG0431	NADPH-dependent FMN reductase
Apar_0267	COG1418	mRNA catabolic process
Apar_0268	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Apar_0272	COG4988	ABC transporter
Apar_0273	COG1132	(ABC) transporter
Apar_0280	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Apar_0281	COG1121	(ABC) transporter
Apar_0282	COG0803	Belongs to the bacterial solute-binding protein 9 family
Apar_0283	COG1028	Short-chain dehydrogenase reductase Sdr
Apar_0285	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Apar_0285	COG2207	Transcriptional regulator
Apar_0289	COG0584	glycerophosphoryl diester phosphodiesterase
Apar_0290	COG2217	Heavy metal translocating P-type atpase
Apar_0291	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Apar_0292	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
Apar_0293	COG0402	S-adenosylhomocysteine deaminase activity
Apar_0294	COG0523	cobalamin synthesis protein
Apar_0295	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Apar_0298	COG2755	lipolytic protein G-D-S-L family
Apar_0298	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Apar_0301	COG1528	Iron-storage protein
Apar_0303	COG0252	asparaginase activity
Apar_0306	COG4868	Belongs to the UPF0371 family
Apar_0314	COG1482	cell wall glycoprotein biosynthetic process
Apar_0316	COG1970	mechanosensitive ion channel activity
Apar_0317	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
Apar_0318	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Apar_0319	COG1181	Belongs to the D-alanine--D-alanine ligase family
Apar_0321	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Apar_0321	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Apar_0321	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Apar_0323	COG0217	transcriptional regulatory protein
Apar_0324	COG1349	DNA-binding transcription factor activity
Apar_0326	COG3037	sugar-specific permease SgaT UlaA
Apar_0331	COG3623	hexulose-6-phosphate isomerase
Apar_0332	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Apar_0333	COG3959	Transketolase, thiamine diphosphate binding domain
Apar_0334	COG3958	Transketolase
Apar_0336	COG1132	(ABC) transporter
Apar_0337	COG0493	'glutamate synthase
Apar_0337	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
Apar_0338	COG0543	2 iron, 2 sulfur cluster binding
Apar_0339	COG0193	aminoacyl-tRNA hydrolase activity
Apar_0340	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
Apar_0342	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Apar_0343	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Apar_0344	COG3409	Peptidoglycan-binding domain 1 protein
Apar_0344	COG3773	Cell wall hydrolase
Apar_0345	COG0142	geranyltranstransferase activity
Apar_0346	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Apar_0348	COG1136	(ABC) transporter
Apar_0348	COG0577	efflux transmembrane transporter activity
Apar_0351	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Apar_0355	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Apar_0356	COG0205	6-phosphofructokinase activity
Apar_0357	COG0205	6-phosphofructokinase activity
Apar_0358	COG0148	phosphopyruvate hydratase activity
Apar_0360	COG3973	AAA domain
Apar_0361	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Apar_0363	COG1131	(ABC) transporter
Apar_0375	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Apar_0377	COG0577	efflux transmembrane transporter activity
Apar_0377	COG1136	(ABC) transporter
Apar_0379	COG0697	spore germination
Apar_0382	COG0210	DNA helicase
Apar_0384	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Apar_0385	COG0306	phosphate transporter
Apar_0391	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Apar_0394	COG1362	aminopeptidase activity
Apar_0396	COG0191	fructose-bisphosphate aldolase activity
Apar_0397	COG1959	2 iron, 2 sulfur cluster binding
Apar_0398	COG0822	iron-sulfur transferase activity
Apar_0399	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Apar_0401	COG0719	Fe-S assembly protein
Apar_0402	COG0396	ATPase activity
Apar_0403	COG0124	histidyl-tRNA synthetase
Apar_0405	COG2801	Transposase and inactivated derivatives
Apar_0407	COG1136	(ABC) transporter
Apar_0407	COG0577	efflux transmembrane transporter activity
Apar_0408	COG1757	Na H antiporter
Apar_0409	COG0583	DNA-binding transcription factor activity
Apar_0410	COG0564	pseudouridine synthase activity
Apar_0418	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Apar_0420	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Apar_0421	COG1132	(ABC) transporter
Apar_0422	COG1132	(ABC) transporter
Apar_0423	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Apar_0424	COG3708	Transcriptional regulator
Apar_0424	COG2207	Transcriptional regulator
Apar_0425	COG2814	Major facilitator Superfamily
Apar_0426	COG0588	phosphoglycerate mutase activity
Apar_0428	COG0174	glutamine synthetase
Apar_0429	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Apar_0430	COG0765	amino acid transport
Apar_0432	COG0745	RESPONSE REGULATOR receiver
Apar_0433	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Apar_0434	COG1322	Protein conserved in bacteria
Apar_0435	COG4555	ABC transporter
Apar_0438	COG1937	Protein conserved in bacteria
Apar_0439	COG2217	Heavy metal translocating P-type atpase
Apar_0440	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Apar_0441	COG1397	ADP-ribosylglycohydrolase
Apar_0443	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Apar_0445	COG0765	amino acid transport
Apar_0446	COG0765	amino acid transport
Apar_0447	COG1126	abc transporter atp-binding protein
Apar_0451	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Apar_0455	COG1191	sigma factor activity
Apar_0457	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Apar_0458	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Apar_0459	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Apar_0460	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
Apar_0461	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Apar_0463	COG0006	proline dipeptidase activity
Apar_0465	COG3715	PTS system
Apar_0466	COG3716	PTS system mannose fructose sorbose family IID component
Apar_0468	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Apar_0470	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Apar_0472	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
Apar_0473	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Apar_0474	COG0497	DNA recombination
Apar_0475	COG0504	CTP synthase activity
Apar_0476	COG4974	Belongs to the 'phage' integrase family
Apar_0477	COG2001	Belongs to the MraZ family
Apar_0478	COG0275	rRNA processing
Apar_0480	COG0768	penicillin binding
Apar_0481	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Apar_0482	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Apar_0483	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Apar_0484	COG0772	Belongs to the SEDS family
Apar_0485	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Apar_0486	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Apar_0487	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Apar_0488	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Apar_0489	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Apar_0491	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Apar_0492	COG1799	cell septum assembly
Apar_0493	COG0762	integral membrane protein
Apar_0497	COG0617	tRNA 3'-terminal CCA addition
Apar_0498	COG1511	domain protein
Apar_0498	COG1511	domain protein
Apar_0501	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Apar_0503	COG1760	l-serine dehydratase
Apar_0504	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Apar_0506	COG1362	aminopeptidase activity
Apar_0508	COG1132	(ABC) transporter
Apar_0513	COG0436	Aminotransferase
Apar_0516	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Apar_0518	COG0343	queuine tRNA-ribosyltransferase activity
Apar_0519	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
Apar_0519	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Apar_0520	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Apar_0521	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Apar_0522	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Apar_0523	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Apar_0524	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Apar_0525	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Apar_0528	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
Apar_0529	COG0018	arginyl-trna synthetase
Apar_0537	COG0410	ABC transporter
Apar_0538	COG0083	homoserine kinase activity
Apar_0541	COG0527	aspartate kinase activity
Apar_0542	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Apar_0549	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Apar_0551	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Apar_0567	COG0582	viral genome integration into host DNA
Apar_0598	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
Apar_0599	COG1105	Belongs to the carbohydrate kinase PfkB family
Apar_0601	COG1597	lipid kinase activity
Apar_0607	COG3842	ATPase activity
Apar_0608	COG1640	4-alpha-glucanotransferase
Apar_0609	COG0058	SHG alpha-glucan phosphorylase activity
Apar_0610	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Apar_0611	COG2094	Belongs to the DNA glycosylase MPG family
Apar_0612	COG0505	Belongs to the CarA family
Apar_0613	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Apar_0615	COG0740	serine-type endopeptidase activity
Apar_0616	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Apar_0619	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Apar_0620	COG0525	valine-tRNA ligase activity
Apar_0621	COG2759	Belongs to the formate--tetrahydrofolate ligase family
Apar_0624	COG0302	gtp cyclohydrolase
Apar_0625	COG0285	dihydrofolate synthase activity
Apar_0628	COG0626	cystathionine gamma-synthase activity
Apar_0629	COG1012	belongs to the aldehyde dehydrogenase family
Apar_0629	COG1454	alcohol dehydrogenase
Apar_0632	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
Apar_0638	COG1597	lipid kinase activity
Apar_0639	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
Apar_0640	COG2738	Putative neutral zinc metallopeptidase
Apar_0641	COG1570	exodeoxyribonuclease VII activity
Apar_0642	COG1722	exodeoxyribonuclease VII activity
Apar_0643	COG0537	adenosine 5'-monophosphoramidase activity
Apar_0644	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Apar_0647	COG0562	UDP-galactopyranose mutase
Apar_0652	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Apar_0653	COG0180	Tryptophanyl-tRNA synthetase
Apar_0654	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Apar_0655	COG1882	Formate acetyltransferase
Apar_0658	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Apar_0659	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Apar_0660	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Apar_0662	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Apar_0664	COG0352	thiamine-phosphate diphosphorylase activity
Apar_0665	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Apar_0666	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Apar_0668	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Apar_0670	COG1077	Cell shape determining protein MreB Mrl
Apar_0673	COG0768	penicillin binding
Apar_0674	COG0772	Belongs to the SEDS family
Apar_0678	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Apar_0679	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Apar_0681	COG1122	ATPase activity
Apar_0682	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
Apar_0683	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Apar_0684	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Apar_0685	COG1713	HD superfamily hydrolase involved in NAD metabolism
Apar_0686	COG0799	negative regulation of ribosome biogenesis
Apar_0688	COG0228	four-way junction DNA binding
Apar_0691	COG0336	Belongs to the RNA methyltransferase TrmD family
Apar_0692	COG0681	Belongs to the peptidase S26 family
Apar_0693	COG0752	glycyl-tRNA synthetase alpha subunit
Apar_0694	COG0751	glycine-tRNA ligase activity
Apar_0695	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
Apar_0696	COG0574	Belongs to the PEP-utilizing enzyme family
Apar_0696	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Apar_0697	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Apar_0698	COG0335	large ribosomal subunit rRNA binding
Apar_0699	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Apar_0700	COG0792	nuclease activity
Apar_0703	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
Apar_0704	COG4974	Belongs to the 'phage' integrase family
Apar_0705	COG0052	Belongs to the universal ribosomal protein uS2 family
Apar_0706	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Apar_0707	COG0528	UMP kinase activity
Apar_0708	COG0233	cytoplasmic translational termination
Apar_0709	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Apar_0710	COG0575	Belongs to the CDS family
Apar_0711	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Apar_0712	COG0750	zinc metalloprotease
Apar_0713	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Apar_0714	COG0442	prolyl-tRNA aminoacylation
Apar_0719	COG0488	(ABC) transporter
Apar_0720	COG1994	Peptidase M50
Apar_0722	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Apar_0723	COG1187	pseudouridine synthase activity
Apar_0724	COG0588	phosphoglycerate mutase activity
Apar_0726	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Apar_0728	COG1160	GTP binding
Apar_0729	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Apar_0730	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Apar_0731	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Apar_0734	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Apar_0736	COG0488	(ABC) transporter
Apar_0737	COG1132	(ABC) transporter
Apar_0738	COG1132	(ABC) transporter
Apar_0740	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Apar_0740	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Apar_0742	COG1151	hydroxylamine reductase activity
Apar_0743	COG0446	pyridine nucleotide-disulphide oxidoreductase
Apar_0744	COG2226	methyltransferase
Apar_0745	COG4716	Myosin-crossreactive antigen
Apar_0746	COG2226	methyltransferase
Apar_0747	COG0561	phosphatase activity
Apar_0750	COG1686	Belongs to the peptidase S11 family
Apar_0755	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Apar_0758	COG2226	methyltransferase
Apar_0759	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
Apar_0759	COG0456	acetyltransferase
Apar_0760	COG0346	lactoylglutathione lyase activity
Apar_0761	COG2226	methyltransferase
Apar_0766	COG2252	PERMEase
Apar_0767	COG0756	dUTP diphosphatase activity
Apar_0768	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Apar_0770	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Apar_0772	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Apar_0773	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Apar_0774	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Apar_0775	COG2359	stage V sporulation protein S
Apar_0776	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Apar_0777	COG1418	mRNA catabolic process
Apar_0779	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Apar_0781	COG1546	Belongs to the CinA family
Apar_0781	COG1058	Belongs to the CinA family
Apar_0782	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Apar_0783	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Apar_0784	COG1666	GTP binding
Apar_0787	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Apar_0788	COG1185	polyribonucleotide nucleotidyltransferase activity
Apar_0791	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Apar_0792	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
Apar_0795	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Apar_0796	COG0484	heat shock protein binding
Apar_0797	COG0484	heat shock protein binding
Apar_0799	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Apar_0801	COG0481	GTPase activity
Apar_0802	COG0268	Binds directly to 16S ribosomal RNA
Apar_0804	COG0658	competence protein
Apar_0804	COG2333	competence protein COMEC
Apar_0805	COG1596	polysaccharide export
Apar_0805	COG1555	photosystem II stabilization
Apar_0806	COG0301	tRNA thio-modification
Apar_0808	COG0194	GDP metabolic process
Apar_0810	COG0284	orotidine-5'-phosphate decarboxylase activity
Apar_0811	COG0167	dihydroorotate dehydrogenase activity
Apar_0812	COG0543	2 iron, 2 sulfur cluster binding
Apar_0814	COG0540	Belongs to the ATCase OTCase family
Apar_0815	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
Apar_0817	COG1609	Transcriptional regulator
Apar_0820	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
Apar_0821	COG4211	Belongs to the binding-protein-dependent transport system permease family
Apar_0822	COG1129	ABC transporter
Apar_0823	COG1879	ABC-type sugar transport system periplasmic component
Apar_0824	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Apar_0826	COG0196	riboflavin kinase activity
Apar_0829	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Apar_0830	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Apar_0831	COG0195	Participates in both transcription termination and antitermination
Apar_0832	COG0779	Required for maturation of 30S ribosomal subunits
Apar_0833	COG0495	leucyl-tRNA aminoacylation
Apar_0834	COG0517	IMP dehydrogenase activity
Apar_0834	COG0516	GMP reductase activity
Apar_0838	COG2207	Transcriptional regulator
Apar_0839	COG0564	pseudouridine synthase activity
Apar_0841	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Apar_0842	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Apar_0843	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Apar_0844	COG1395	domain, Protein
Apar_0848	COG2832	Protein of unknown function (DUF454)
Apar_0849	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Apar_0851	COG1196	nuclear chromosome segregation
Apar_0852	COG0571	ribonuclease III activity
Apar_0853	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Apar_0855	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Apar_0858	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Apar_0860	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Apar_0861	COG1461	Dihydroxyacetone kinase
Apar_0862	COG1302	Protein conserved in bacteria
Apar_0863	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Apar_0866	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Apar_0866	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Apar_0867	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Apar_0869	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Apar_0872	COG3022	response to hydroperoxide
Apar_0875	COG1950	PFAM Membrane protein of
Apar_0876	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Apar_0878	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Apar_0879	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Apar_0881	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Apar_0881	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Apar_0884	COG1132	(ABC) transporter
Apar_0885	COG1132	(ABC) transporter
Apar_0886	COG0546	phosphoglycolate phosphatase activity
Apar_0890	COG1278	Cold shock
Apar_0891	COG1376	ErfK ybiS ycfS ynhG family protein
Apar_0894	COG0632	four-way junction helicase activity
Apar_0895	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Apar_0897	COG2033	superoxide reductase activity
Apar_0898	COG0587	DNA-directed DNA polymerase activity
Apar_0899	COG3579	cysteine-type endopeptidase activity
Apar_0903	COG1739	Uncharacterized protein family UPF0029
Apar_0908	COG0450	alkyl hydroperoxide reductase
Apar_0912	COG0482	sulfurtransferase activity
Apar_0913	COG1104	cysteine desulfurase activity
Apar_0915	COG1366	Belongs to the anti-sigma-factor antagonist family
Apar_0923	COG0126	phosphoglycerate kinase activity
Apar_0925	COG1481	regulation of sporulation
Apar_0926	COG1660	Displays ATPase and GTPase activities
Apar_0927	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
Apar_0929	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Apar_0932	COG4608	Belongs to the ABC transporter superfamily
Apar_0933	COG0444	Belongs to the ABC transporter superfamily
Apar_0935	COG0747	negative chemotaxis
Apar_0938	COG0322	excinuclease ABC activity
Apar_0940	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Apar_0941	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Apar_0942	COG2731	YhcH YjgK YiaL family protein
Apar_0945	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
Apar_0946	COG0556	nucleotide-excision repair
Apar_0948	COG0237	dephospho-CoA kinase activity
Apar_0949	COG3842	ATPase activity
Apar_0953	COG2195	Cleaves the N-terminal amino acid of tripeptides
Apar_0954	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Apar_0955	COG0747	negative chemotaxis
Apar_0956	COG4608	Belongs to the ABC transporter superfamily
Apar_0957	COG0444	Belongs to the ABC transporter superfamily
Apar_0958	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Apar_0959	COG0601	transmembrane transport
Apar_0969	COG1846	Transcriptional regulator
Apar_0972	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Apar_0972	COG1918	ferrous iron import across plasma membrane
Apar_0974	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
Apar_0981	COG2084	Dehydrogenase
Apar_0982	COG1307	EDD domain protein, DegV family
Apar_0983	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Apar_0985	COG1040	competence protein
Apar_0993	COG0717	Belongs to the dCTP deaminase family
Apar_0994	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
Apar_0997	COG1216	Glycosyl transferase, family 2
Apar_1000	COG3475	LICD family
Apar_1003	COG4750	Nucleotidyl transferase
Apar_1004	COG3475	LICD family
Apar_1006	COG1091	dTDP-4-dehydrorhamnose reductase activity
Apar_1009	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Apar_1010	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Apar_1011	COG1438	arginine binding
Apar_1013	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Apar_1014	COG0116	Belongs to the methyltransferase superfamily
Apar_1014	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Apar_1015	COG3158	transport of potassium into the cell
Apar_1017	COG3830	Belongs to the UPF0237 family
Apar_1035	COG2894	cell division
Apar_1037	COG1162	GTPase activity
Apar_1039	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Apar_1041	COG1132	(ABC) transporter
Apar_1044	COG0745	RESPONSE REGULATOR receiver
Apar_1045	COG3850	Histidine kinase
Apar_1045	COG5002	protein histidine kinase activity
Apar_1047	COG0297	glycogen (starch) synthase activity
Apar_1048	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Apar_1049	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Apar_1050	COG0058	SHG alpha-glucan phosphorylase activity
Apar_1051	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Apar_1052	COG0371	Dehydrogenase
Apar_1054	COG0072	phenylalanine-tRNA ligase activity
Apar_1055	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Apar_1056	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Apar_1057	COG1121	(ABC) transporter
Apar_1058	COG0803	Belongs to the bacterial solute-binding protein 9 family
Apar_1059	COG2323	membrane
Apar_1062	COG2222	sugar isomerase
Apar_1064	COG3716	PTS system mannose fructose sorbose family IID component
Apar_1065	COG3715	PTS system
Apar_1066	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Apar_1067	COG1862	Preprotein translocase
Apar_1071	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Apar_1072	COG3189	MarR family transcriptional regulator
Apar_1077	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Apar_1077	COG1263	PTS System
Apar_1077	COG2190	(PTS) system
Apar_1078	COG0577	efflux transmembrane transporter activity
Apar_1078	COG0577	efflux transmembrane transporter activity
Apar_1079	COG1136	(ABC) transporter
Apar_1081	COG2205	protein histidine kinase activity
Apar_1082	COG0745	RESPONSE REGULATOR receiver
Apar_1084	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Apar_1085	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Apar_1085	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Apar_1087	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Apar_1089	COG0720	synthase
Apar_1090	COG1774	PSP1 C-terminal conserved region
Apar_1092	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Apar_1093	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Apar_1094	COG0805	protein transport
Apar_1095	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Apar_1096	COG1366	Belongs to the anti-sigma-factor antagonist family
Apar_1098	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Apar_1103	COG0328	RNA-DNA hybrid ribonuclease activity
Apar_1104	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Apar_1104	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Apar_1109	COG1393	Belongs to the ArsC family
Apar_1112	COG1442	glycosyl transferase family 8
Apar_1117	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Apar_1120	COG1979	alcohol dehydrogenase
Apar_1121	COG1307	EDD domain protein, DegV family
Apar_1124	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Apar_1124	COG1328	CTP reductase activity
Apar_1126	COG1216	Glycosyl transferase, family 2
Apar_1129	COG0101	tRNA pseudouridine synthase activity
Apar_1130	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
Apar_1131	COG3845	ABC transporter
Apar_1132	COG0203	ribosomal protein L17
Apar_1134	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Apar_1135	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Apar_1136	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Apar_1137	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Apar_1138	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Apar_1140	COG0563	adenylate kinase activity
Apar_1143	COG1841	ribosomal large subunit assembly
Apar_1144	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Apar_1145	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Apar_1147	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Apar_1152	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Apar_1153	COG0255	Belongs to the universal ribosomal protein uL29 family
Apar_1154	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Apar_1155	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Apar_1156	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Apar_1157	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Apar_1158	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Apar_1159	COG0089	rRNA binding
Apar_1160	COG0088	Forms part of the polypeptide exit tunnel
Apar_1161	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Apar_1163	COG0051	transcription antitermination factor activity, RNA binding
Apar_1164	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Apar_1165	COG0049	tRNA binding
Apar_1166	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Apar_1168	COG0640	Transcriptional regulator
Apar_1169	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Apar_1170	COG0085	RNA polymerase activity
Apar_1171	COG0222	ribosome binding
Apar_1172	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Apar_1173	COG0081	regulation of translation
Apar_1174	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Apar_1175	COG0250	Participates in transcription elongation, termination and antitermination
Apar_1177	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Apar_1178	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Apar_1181	COG0215	cysteine-tRNA ligase activity
Apar_1182	COG1132	(ABC) transporter
Apar_1183	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Apar_1184	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Apar_1185	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
Apar_1187	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Apar_1189	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Apar_1191	COG0281	malic enzyme
Apar_1193	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Apar_1194	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Apar_1196	COG0778	Nitroreductase
Apar_1200	COG1737	Transcriptional regulator
Apar_1201	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Apar_1203	COG1956	GAF domain-containing protein
Apar_1205	COG1164	Oligoendopeptidase f
Apar_1213	COG4268	DNA restriction-modification system
Apar_1223	COG1396	sequence-specific DNA binding
Apar_1224	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
Apar_1230	COG0025	NhaP-type Na H and K H
Apar_1235	COG5002	protein histidine kinase activity
Apar_1236	COG0745	RESPONSE REGULATOR receiver
Apar_1242	COG1335	isochorismatase
Apar_1243	COG0802	atpase or kinase
Apar_1244	COG1573	uracil-dna glycosylase
Apar_1245	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Apar_1246	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Apar_1246	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Apar_1247	COG0736	holo-[acyl-carrier-protein] synthase activity
Apar_1248	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Apar_1250	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Apar_1252	COG1105	Belongs to the carbohydrate kinase PfkB family
Apar_1254	COG1396	sequence-specific DNA binding
Apar_1256	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Apar_1257	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Apar_1258	COG5492	domain, Protein
Apar_1258	COG1621	beta-fructofuranosidase activity
Apar_1258	COG3583	domain protein
Apar_1267	COG1695	Transcriptional regulator
Apar_1268	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Apar_1274	COG0557	exoribonuclease II activity
Apar_1275	COG0402	S-adenosylhomocysteine deaminase activity
Apar_1278	COG2177	Part of the ABC transporter FtsEX involved in
Apar_1279	COG2884	Cell division ATP-binding protein ftsE
Apar_1281	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Apar_1287	COG1349	DNA-binding transcription factor activity
Apar_1288	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Apar_1289	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Apar_1290	COG0653	protein targeting
Apar_1292	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Apar_1293	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Apar_1295	COG1316	TRANSCRIPTIONal
Apar_1296	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Apar_1298	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Apar_1299	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Apar_1300	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Apar_1302	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Apar_1303	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Apar_1304	COG0356	it plays a direct role in the translocation of protons across the membrane
Apar_1307	COG0698	ribose 5-phosphate isomerase
Apar_1309	COG2890	protein-(glutamine-N5) methyltransferase activity
Apar_1310	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Apar_1312	COG0586	Pfam SNARE associated Golgi protein
Apar_1314	COG3716	PTS system mannose fructose sorbose family IID component
Apar_1315	COG3715	PTS system
Apar_1320	COG3118	belongs to the thioredoxin family
Apar_1321	COG0671	phosphoesterase, PA-phosphatase related
Apar_1323	COG3279	Response regulator of the LytR AlgR family
Apar_1324	COG3275	phosphorelay sensor kinase activity
Apar_1330	COG0138	bifunctional purine biosynthesis protein purh
Apar_1332	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Apar_1333	COG5002	protein histidine kinase activity
Apar_1335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Apar_1335	COG1263	PTS System
Apar_1336	COG0366	Alpha amylase catalytic
Apar_1338	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Apar_1340	COG2815	serine threonine protein kinase
Apar_1340	COG0515	serine threonine protein kinase
Apar_1341	COG1716	ATPase activity
Apar_1341	COG1131	(ABC) transporter
Apar_1341	COG0842	Transport permease protein
Apar_1343	COG0631	protein serine/threonine phosphatase activity
Apar_1345	COG0515	serine threonine protein kinase
Apar_1345	COG2815	serine threonine protein kinase
Apar_1347	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Apar_1348	COG5002	protein histidine kinase activity
Apar_1349	COG0745	RESPONSE REGULATOR receiver
Apar_1351	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Apar_1359	COG1199	ATP-dependent helicase activity
Apar_1359	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Apar_1360	COG1181	Belongs to the D-alanine--D-alanine ligase family
Apar_1361	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Apar_1362	COG1475	DNA binding
Apar_1363	COG1192	Involved in chromosome partitioning
Apar_1364	COG0357	Ribosomal RNA small subunit methyltransferase G
Apar_1365	COG1847	R3H domain protein
Apar_1366	COG0706	membrane insertase activity
Apar_1367	COG0759	Could be involved in insertion of integral membrane proteins into the membrane