locus-tag	class	description
RT761_00001	COG0191	fructose-bisphosphate aldolase activity
RT761_00007	COG0395	ABC-type sugar transport system, permease component
RT761_00008	COG1175	transmembrane transport
RT761_00011	COG2186	Transcriptional regulator
RT761_00013	COG4948	Mandelate Racemase Muconate Lactonizing
RT761_00019	COG3290	protein histidine kinase activity
RT761_00020	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
RT761_00023	COG0395	ABC-type sugar transport system, permease component
RT761_00024	COG1175	transmembrane transport
RT761_00026	COG1028	Short-chain dehydrogenase reductase Sdr
RT761_00033	COG0798	PFAM Bile acid sodium symporter
RT761_00037	COG3118	belongs to the thioredoxin family
RT761_00044	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
RT761_00045	COG0135	phosphoribosylanthranilate isomerase activity
RT761_00047	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
RT761_00049	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RT761_00052	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
RT761_00054	COG2226	methyltransferase
RT761_00059	COG0095	Lipoate-protein ligase
RT761_00060	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
RT761_00061	COG0508	dehydrogenase complex catalyzes the overall conversion of
RT761_00066	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
RT761_00066	COG0758	DNA mediated transformation
RT761_00067	COG0606	chelatase, subunit chli
RT761_00068	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
RT761_00071	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
RT761_00072	COG0681	Belongs to the peptidase S26 family
RT761_00073	COG0335	large ribosomal subunit rRNA binding
RT761_00074	COG0336	Belongs to the RNA methyltransferase TrmD family
RT761_00075	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
RT761_00077	COG0228	four-way junction DNA binding
RT761_00078	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
RT761_00079	COG0552	protein localization to endoplasmic reticulum
RT761_00080	COG1196	nuclear chromosome segregation
RT761_00081	COG0571	ribonuclease III activity
RT761_00084	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
RT761_00085	COG2070	2-Nitropropane dioxygenase
RT761_00086	COG0416	fatty acid biosynthetic process
RT761_00087	COG0333	Belongs to the bacterial ribosomal protein bL32 family
RT761_00089	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
RT761_00090	COG0280	phosphate acetyltransferase
RT761_00091	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
RT761_00092	COG0742	ribosomal rna small subunit methyltransferase
RT761_00093	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
RT761_00094	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
RT761_00096	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RT761_00096	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
RT761_00097	COG2738	Putative neutral zinc metallopeptidase
RT761_00098	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
RT761_00099	COG0242	peptide deformylase activity
RT761_00100	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
RT761_00101	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
RT761_00103	COG0194	GDP metabolic process
RT761_00104	COG1561	YicC-like family, N-terminal region
RT761_00106	COG0564	pseudouridine synthase activity
RT761_00107	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
RT761_00108	COG3599	regulation of cell shape
RT761_00109	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
RT761_00110	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
RT761_00112	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
RT761_00114	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
RT761_00115	COG0812	UDP-N-acetylmuramate dehydrogenase activity
RT761_00116	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
RT761_00117	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
RT761_00118	COG0772	Belongs to the SEDS family
RT761_00119	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
RT761_00120	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RT761_00121	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
RT761_00122	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
RT761_00125	COG0275	rRNA processing
RT761_00126	COG2001	Belongs to the MraZ family
RT761_00130	COG2172	sigma factor antagonist activity
RT761_00133	COG0525	valine-tRNA ligase activity
RT761_00134	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
RT761_00135	COG0740	serine-type endopeptidase activity
RT761_00136	COG0544	peptidyl-prolyl cis-trans isomerase activity
RT761_00139	COG1131	(ABC) transporter
RT761_00140	COG0640	Transcriptional regulator
RT761_00157	COG3547	Transposase (IS116 IS110 IS902 family)
RT761_00158	COG1598	PFAM Uncharacterised protein family UPF0150
RT761_00162	COG1234	tRNA 3'-trailer cleavage
RT761_00166	COG0445	tRNA wobble uridine modification
RT761_00168	COG0445	tRNA wobble uridine modification
RT761_00169	COG0395	ABC-type sugar transport system, permease component
RT761_00170	COG1175	transmembrane transport
RT761_00171	COG1609	Transcriptional regulator
RT761_00173	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
RT761_00174	COG0527	aspartate kinase activity
RT761_00175	COG0083	homoserine kinase activity
RT761_00176	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
RT761_00177	COG1959	2 iron, 2 sulfur cluster binding
RT761_00180	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RT761_00181	COG0493	'glutamate synthase
RT761_00181	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
RT761_00183	COG0067	glutamate synthase
RT761_00184	COG0174	glutamine synthetase
RT761_00187	COG0131	Imidazoleglycerol-phosphate dehydratase
RT761_00189	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
RT761_00190	COG0107	imidazoleglycerol-phosphate synthase activity
RT761_00191	COG0140	phosphoribosyl-ATP diphosphatase activity
RT761_00191	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
RT761_00195	COG1129	ABC transporter
RT761_00198	COG0697	spore germination
RT761_00200	COG0436	Aminotransferase
RT761_00202	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RT761_00203	COG0215	cysteine-tRNA ligase activity
RT761_00205	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
RT761_00206	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
RT761_00207	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
RT761_00208	COG4956	integral membrane protein (PIN domain superfamily)
RT761_00209	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
RT761_00210	COG0542	response to heat
RT761_00211	COG3869	Catalyzes the specific phosphorylation of arginine residues in
RT761_00213	COG4463	regulation of RNA biosynthetic process
RT761_00214	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
RT761_00217	COG2223	nitrite transmembrane transporter activity
RT761_00218	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
RT761_00220	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_00221	COG1129	ABC transporter
RT761_00224	COG1175	transmembrane transport
RT761_00227	COG2801	Transposase and inactivated derivatives
RT761_00227	COG3415	Transposase
RT761_00239	COG3706	GGDEF domain
RT761_00240	COG0489	protein tyrosine kinase activity
RT761_00242	COG0731	radical SAM domain protein
RT761_00242	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
RT761_00243	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RT761_00251	COG0735	belongs to the Fur family
RT761_00253	COG0022	dehydrogenase e1 component
RT761_00254	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RT761_00255	COG0395	ABC-type sugar transport system, permease component
RT761_00256	COG1175	transmembrane transport
RT761_00259	COG0191	fructose-bisphosphate aldolase activity
RT761_00265	COG1253	flavin adenine dinucleotide binding
RT761_00267	COG2373	Large extracellular alpha-helical protein
RT761_00268	COG3234	Protein of unknown function (DUF1175)
RT761_00269	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RT761_00270	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
RT761_00271	COG0167	dihydroorotate dehydrogenase activity
RT761_00272	COG0543	2 iron, 2 sulfur cluster binding
RT761_00273	COG0284	orotidine-5'-phosphate decarboxylase activity
RT761_00274	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
RT761_00275	COG0540	Belongs to the ATCase OTCase family
RT761_00276	COG1070	Carbohydrate kinase
RT761_00277	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
RT761_00278	COG2140	Oxalate decarboxylase
RT761_00280	COG0673	inositol 2-dehydrogenase activity
RT761_00281	COG2188	Transcriptional regulator
RT761_00286	COG0395	ABC-type sugar transport system, permease component
RT761_00288	COG1653	transport
RT761_00289	COG1012	belongs to the aldehyde dehydrogenase family
RT761_00290	COG1070	Carbohydrate kinase
RT761_00294	COG0277	FAD linked oxidase domain protein
RT761_00296	COG1070	Carbohydrate kinase
RT761_00298	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_00299	COG1129	ABC transporter
RT761_00302	COG0800	Aldolase
RT761_00303	COG1525	nuclease
RT761_00304	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RT761_00306	COG1704	LemA family
RT761_00309	COG0697	spore germination
RT761_00310	COG0222	ribosome binding
RT761_00311	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
RT761_00312	COG0081	regulation of translation
RT761_00313	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
RT761_00314	COG0250	Participates in transcription elongation, termination and antitermination
RT761_00315	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
RT761_00317	COG0267	Belongs to the bacterial ribosomal protein bL33 family
RT761_00318	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
RT761_00322	COG3153	acetyltransferase
RT761_00322	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RT761_00328	COG1070	Carbohydrate kinase
RT761_00329	COG2878	Part of a membrane complex involved in electron transport
RT761_00329	COG1245	4Fe-4S binding domain
RT761_00330	COG4657	Part of a membrane complex involved in electron transport
RT761_00331	COG4660	Part of a membrane complex involved in electron transport
RT761_00332	COG4659	FMN binding
RT761_00333	COG4658	electron transport chain
RT761_00334	COG4656	Part of a membrane complex involved in electron transport
RT761_00335	COG0439	Biotin carboxylase
RT761_00336	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
RT761_00337	COG0330	HflC and HflK could
RT761_00338	COG0330	HflC and HflK could
RT761_00341	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
RT761_00344	COG1063	alcohol dehydrogenase
RT761_00346	COG0693	protein deglycase activity
RT761_00349	COG1132	(ABC) transporter
RT761_00350	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RT761_00351	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RT761_00353	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RT761_00354	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
RT761_00355	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RT761_00357	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RT761_00360	COG1077	Cell shape determining protein MreB Mrl
RT761_00361	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
RT761_00367	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RT761_00368	COG4481	Protein conserved in bacteria
RT761_00369	COG0778	Nitroreductase
RT761_00374	COG1454	alcohol dehydrogenase
RT761_00376	COG0667	Aldo Keto reductase
RT761_00377	COG0019	diaminopimelate decarboxylase activity
RT761_00379	COG1079	Belongs to the binding-protein-dependent transport system permease family
RT761_00381	COG3845	ABC transporter
RT761_00382	COG0473	3-isopropylmalate dehydrogenase activity
RT761_00383	COG0179	Fumarylacetoacetate (FAA) hydrolase
RT761_00385	COG4372	Transposase
RT761_00387	COG1137	ATPase activity
RT761_00394	COG0463	Glycosyl transferase, family 2
RT761_00395	COG0628	permease
RT761_00396	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
RT761_00401	COG1595	DNA-templated transcription, initiation
RT761_00403	COG1045	serine acetyltransferase
RT761_00406	COG1609	Transcriptional regulator
RT761_00410	COG1609	Transcriptional regulator
RT761_00411	COG1879	ABC-type sugar transport system periplasmic component
RT761_00412	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_00413	COG1129	ABC transporter
RT761_00416	COG5609	conserved protein (DUF2294)
RT761_00419	COG1082	Xylose isomerase domain protein TIM barrel
RT761_00422	COG2264	protein methyltransferase activity
RT761_00423	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
RT761_00424	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
RT761_00431	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RT761_00432	COG0493	'glutamate synthase
RT761_00432	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
RT761_00435	COG0756	dUTP diphosphatase activity
RT761_00436	COG0058	SHG alpha-glucan phosphorylase activity
RT761_00440	COG0017	Asparaginyl-tRNA synthetase
RT761_00443	COG0559	Belongs to the binding-protein-dependent transport system permease family
RT761_00449	COG1181	Belongs to the D-alanine--D-alanine ligase family
RT761_00452	COG1098	S1 RNA binding domain
RT761_00454	COG0148	phosphopyruvate hydratase activity
RT761_00455	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
RT761_00457	COG3956	TIGRFAM MazG family protein
RT761_00458	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
RT761_00460	COG0193	aminoacyl-tRNA hydrolase activity
RT761_00461	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
RT761_00463	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
RT761_00465	COG2848	UPF0210 protein
RT761_00466	COG3830	Belongs to the UPF0237 family
RT761_00467	COG1515	deoxyribonuclease V activity
RT761_00469	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
RT761_00473	COG0084	hydrolase, TatD family'
RT761_00474	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RT761_00474	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RT761_00475	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RT761_00475	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RT761_00476	COG0534	Mate efflux family protein
RT761_00480	COG3415	Transposase
RT761_00480	COG2801	Transposase and inactivated derivatives
RT761_00483	COG2801	Transposase and inactivated derivatives
RT761_00486	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
RT761_00488	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
RT761_00490	COG1210	Utp--glucose-1-phosphate uridylyltransferase
RT761_00493	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
RT761_00512	COG0438	transferase activity, transferring glycosyl groups
RT761_00513	COG3307	-O-antigen
RT761_00514	COG1216	Glycosyl transferase, family 2
RT761_00514	COG0463	Glycosyl transferase, family 2
RT761_00519	COG1132	(ABC) transporter
RT761_00520	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
RT761_00530	COG3415	Transposase
RT761_00530	COG2801	Transposase and inactivated derivatives
RT761_00536	COG0667	Aldo Keto reductase
RT761_00541	COG1528	Iron-storage protein
RT761_00542	COG0426	domain, Protein
RT761_00543	COG3706	GGDEF domain
RT761_00546	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
RT761_00548	COG2861	carbohydrate metabolic process
RT761_00549	COG0793	Belongs to the peptidase S41A family
RT761_00552	COG2884	Cell division ATP-binding protein ftsE
RT761_00556	COG0511	ligase activity, forming carbon-carbon bonds
RT761_00558	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RT761_00560	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
RT761_00561	COG0653	protein targeting
RT761_00563	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
RT761_00566	COG1105	Belongs to the carbohydrate kinase PfkB family
RT761_00567	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RT761_00568	COG1070	Carbohydrate kinase
RT761_00569	COG0508	dehydrogenase complex catalyzes the overall conversion of
RT761_00571	COG1028	Short-chain dehydrogenase reductase Sdr
RT761_00573	COG1070	Carbohydrate kinase
RT761_00574	COG1082	Xylose isomerase domain protein TIM barrel
RT761_00575	COG1070	Carbohydrate kinase
RT761_00577	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RT761_00578	COG1063	alcohol dehydrogenase
RT761_00580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RT761_00581	COG2390	Transcriptional regulator
RT761_00582	COG1040	competence protein
RT761_00588	COG2176	DNA-directed DNA polymerase activity
RT761_00588	COG5002	protein histidine kinase activity
RT761_00595	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
RT761_00598	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_00599	COG1129	ABC transporter
RT761_00601	COG1082	Xylose isomerase domain protein TIM barrel
RT761_00603	COG1879	ABC-type sugar transport system periplasmic component
RT761_00605	COG1129	ABC transporter
RT761_00606	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_00608	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
RT761_00609	COG1063	alcohol dehydrogenase
RT761_00610	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_00611	COG4603	Belongs to the binding-protein-dependent transport system permease family
RT761_00612	COG1129	ABC transporter
RT761_00613	COG1609	Transcriptional regulator
RT761_00614	COG1063	alcohol dehydrogenase
RT761_00615	COG4869	propanediol catabolic process
RT761_00616	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
RT761_00617	COG0698	ribose 5-phosphate isomerase
RT761_00619	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
RT761_00620	COG1012	belongs to the aldehyde dehydrogenase family
RT761_00623	COG4656	Part of a membrane complex involved in electron transport
RT761_00624	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
RT761_00625	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
RT761_00626	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
RT761_00627	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
RT761_00629	COG1070	Carbohydrate kinase
RT761_00631	COG4214	carbohydrate transport
RT761_00632	COG1129	ABC transporter
RT761_00633	COG4213	ABC transporter substrate-binding protein
RT761_00641	COG1228	amidohydrolase
RT761_00642	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_00643	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_00644	COG1129	ABC transporter
RT761_00646	COG1349	DNA-binding transcription factor activity
RT761_00647	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
RT761_00648	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
RT761_00651	COG0698	ribose 5-phosphate isomerase
RT761_00653	COG1461	Dihydroxyacetone kinase
RT761_00654	COG2376	Dihydroxyacetone kinase
RT761_00655	COG1070	Carbohydrate kinase
RT761_00656	COG1028	Short-chain dehydrogenase reductase Sdr
RT761_00657	COG3842	ATPase activity
RT761_00658	COG3842	ATPase activity
RT761_00660	COG0395	ABC-type sugar transport system, permease component
RT761_00661	COG1175	transmembrane transport
RT761_00663	COG1028	Short-chain dehydrogenase reductase Sdr
RT761_00667	COG1028	Short-chain dehydrogenase reductase Sdr
RT761_00668	COG1082	Xylose isomerase domain protein TIM barrel
RT761_00669	COG1082	Xylose isomerase domain protein TIM barrel
RT761_00670	COG1063	alcohol dehydrogenase
RT761_00674	COG0022	dehydrogenase e1 component
RT761_00675	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RT761_00677	COG0644	oxidoreductase
RT761_00680	COG1609	Transcriptional regulator
RT761_00681	COG1063	alcohol dehydrogenase
RT761_00686	COG0395	ABC-type sugar transport system, permease component
RT761_00687	COG1175	transmembrane transport
RT761_00688	COG1653	transport
RT761_00691	COG0129	dihydroxy-acid dehydratase activity
RT761_00692	COG1028	Short-chain dehydrogenase reductase Sdr
RT761_00694	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_00695	COG1129	ABC transporter
RT761_00697	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RT761_00699	COG3971	2-oxopent-4-enoate hydratase activity
RT761_00700	COG2197	response regulator
RT761_00704	COG0450	alkyl hydroperoxide reductase
RT761_00710	COG1028	Short-chain dehydrogenase reductase Sdr
RT761_00712	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
RT761_00714	COG0446	pyridine nucleotide-disulphide oxidoreductase
RT761_00716	COG1879	ABC-type sugar transport system periplasmic component
RT761_00717	COG1129	ABC transporter
RT761_00718	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_00719	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_00721	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RT761_00723	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_00724	COG1129	ABC transporter
RT761_00727	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RT761_00727	COG5322	oxidoreductase activity
RT761_00732	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
RT761_00733	COG2801	Transposase and inactivated derivatives
RT761_00733	COG3415	Transposase
RT761_00735	COG3191	aminopeptidase activity
RT761_00738	COG0459	protein refolding
RT761_00739	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
RT761_00746	COG1609	Transcriptional regulator
RT761_00749	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RT761_00750	COG0577	efflux transmembrane transporter activity
RT761_00750	COG1136	(ABC) transporter
RT761_00752	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
RT761_00754	COG1104	cysteine desulfurase activity
RT761_00759	COG0671	phosphoesterase, PA-phosphatase related
RT761_00760	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
RT761_00763	COG0129	dihydroxy-acid dehydratase activity
RT761_00764	COG0028	Belongs to the TPP enzyme family
RT761_00765	COG0440	acetolactate synthase activity
RT761_00766	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
RT761_00767	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RT761_00768	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
RT761_00769	COG0066	3-isopropylmalate dehydratase activity
RT761_00771	COG1609	Transcriptional regulator
RT761_00772	COG2264	protein methyltransferase activity
RT761_00774	COG1191	sigma factor activity
RT761_00777	COG0473	3-isopropylmalate dehydrogenase activity
RT761_00780	COG1595	DNA-templated transcription, initiation
RT761_00784	COG2059	Chromate
RT761_00785	COG2059	Chromate
RT761_00786	COG1739	Uncharacterized protein family UPF0029
RT761_00787	COG3850	Histidine kinase
RT761_00787	COG5002	protein histidine kinase activity
RT761_00788	COG0745	RESPONSE REGULATOR receiver
RT761_00791	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
RT761_00791	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
RT761_00799	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RT761_00800	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
RT761_00801	COG0187	DNA topoisomerase II activity
RT761_00803	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
RT761_00804	COG0592	DNA-directed DNA polymerase activity
RT761_00805	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
RT761_00806	COG0395	ABC-type sugar transport system, permease component
RT761_00810	COG1940	carbohydrate kinase activity
RT761_00811	COG0022	dehydrogenase e1 component
RT761_00812	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RT761_00816	COG2084	Dehydrogenase
RT761_00819	COG0167	dihydroorotate dehydrogenase activity
RT761_00820	COG1013	pyruvate-flavodoxin oxidoreductase activity
RT761_00820	COG0674	pyruvate-flavodoxin oxidoreductase activity
RT761_00820	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
RT761_00820	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
RT761_00821	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
RT761_00822	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
RT761_00823	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
RT761_00826	COG1940	carbohydrate kinase activity
RT761_00827	COG0391	Required for morphogenesis under gluconeogenic growth conditions
RT761_00829	COG1175	transmembrane transport
RT761_00832	COG1151	hydroxylamine reductase activity
RT761_00840	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_00841	COG1129	ABC transporter
RT761_00842	COG1879	ABC-type sugar transport system periplasmic component
RT761_00849	COG3328	transposase activity
RT761_00853	COG0277	FAD linked oxidase domain protein
RT761_00854	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
RT761_00855	COG2086	electron transfer activity
RT761_00856	COG0395	ABC-type sugar transport system, permease component
RT761_00857	COG1175	transmembrane transport
RT761_00859	COG1830	Aldolase
RT761_00860	COG1063	alcohol dehydrogenase
RT761_00861	COG1070	Carbohydrate kinase
RT761_00869	COG3459	Glycosyltransferase 36 associated
RT761_00872	COG0432	Pfam Uncharacterised protein family UPF0047
RT761_00878	COG0436	Aminotransferase
RT761_00879	COG0004	ammonium transporteR
RT761_00880	COG0347	Belongs to the P(II) protein family
RT761_00881	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
RT761_00882	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
RT761_00884	COG0860	N-Acetylmuramoyl-L-alanine amidase
RT761_00885	COG0629	single-stranded DNA binding
RT761_00886	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RT761_00889	COG0157	Belongs to the NadC ModD family
RT761_00890	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
RT761_00894	COG4608	Belongs to the ABC transporter superfamily
RT761_00895	COG0444	Belongs to the ABC transporter superfamily
RT761_00896	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RT761_00897	COG0601	transmembrane transport
RT761_00898	COG0747	negative chemotaxis
RT761_00904	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RT761_00909	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RT761_00915	COG0497	DNA recombination
RT761_00921	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
RT761_00925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RT761_00926	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RT761_00935	COG4608	Belongs to the ABC transporter superfamily
RT761_00938	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RT761_00940	COG1722	exodeoxyribonuclease VII activity
RT761_00941	COG1570	exodeoxyribonuclease VII activity
RT761_00942	COG1164	Oligoendopeptidase f
RT761_00948	COG4717	serine-type aminopeptidase activity
RT761_00953	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RT761_00954	COG1181	Belongs to the D-alanine--D-alanine ligase family
RT761_00955	COG2770	Histidine kinase
RT761_00955	COG2205	protein histidine kinase activity
RT761_00956	COG0745	RESPONSE REGULATOR receiver
RT761_00960	COG0577	efflux transmembrane transporter activity
RT761_00960	COG1136	(ABC) transporter
RT761_00961	COG1136	(ABC) transporter
RT761_00965	COG2801	Transposase and inactivated derivatives
RT761_00965	COG3415	Transposase
RT761_00968	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
RT761_00969	COG0482	sulfurtransferase activity
RT761_00970	COG0037	tRNA processing
RT761_00973	COG2003	Belongs to the UPF0758 family
RT761_00975	COG1177	transmembrane transport
RT761_00977	COG3842	ATPase activity
RT761_00980	COG5598	trimethylamine methyltransferase
RT761_00981	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
RT761_00982	COG0656	L-ascorbic acid biosynthetic process
RT761_00983	COG2608	mercury ion transmembrane transporter activity
RT761_00984	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RT761_00986	COG1136	(ABC) transporter
RT761_00988	COG0367	asparagine synthase
RT761_00990	COG2801	Transposase and inactivated derivatives
RT761_00990	COG3415	Transposase
RT761_00991	COG0598	Magnesium transport protein CorA
RT761_00992	COG1181	Belongs to the D-alanine--D-alanine ligase family
RT761_00993	COG0667	Aldo Keto reductase
RT761_00995	COG1940	carbohydrate kinase activity
RT761_00996	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
RT761_00997	COG1070	Carbohydrate kinase
RT761_00998	COG0230	Belongs to the bacterial ribosomal protein bL34 family
RT761_00999	COG0594	ribonuclease P activity
RT761_01001	COG0706	membrane insertase activity
RT761_01002	COG1847	R3H domain protein
RT761_01003	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
RT761_01004	COG0357	Ribosomal RNA small subunit methyltransferase G
RT761_01005	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
RT761_01007	COG1192	Involved in chromosome partitioning
RT761_01008	COG1475	DNA binding
RT761_01009	COG0739	heme binding
RT761_01012	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RT761_01015	COG1881	PFAM PEBP family protein
RT761_01019	COG1230	cation diffusion facilitator family transporter
RT761_01021	COG1592	Rubrerythrin
RT761_01026	COG1175	transmembrane transport
RT761_01027	COG0395	ABC-type sugar transport system, permease component
RT761_01028	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
RT761_01032	COG4974	Belongs to the 'phage' integrase family
RT761_01048	COG1598	PFAM Uncharacterised protein family UPF0150
RT761_01053	COG1609	Transcriptional regulator
RT761_01054	COG1082	Xylose isomerase domain protein TIM barrel
RT761_01057	COG1028	Short-chain dehydrogenase reductase Sdr
RT761_01061	COG4584	PFAM Integrase catalytic
RT761_01062	COG1484	DNA-dependent DNA replication
RT761_01073	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
RT761_01076	COG1598	PFAM Uncharacterised protein family UPF0150
RT761_01079	COG3547	Transposase (IS116 IS110 IS902 family)
RT761_01083	COG1175	transmembrane transport
RT761_01090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RT761_01091	COG1082	Xylose isomerase domain protein TIM barrel
RT761_01092	COG3328	transposase activity
RT761_01093	COG3328	transposase activity
RT761_01096	COG4584	PFAM Integrase catalytic
RT761_01097	COG1484	DNA-dependent DNA replication
RT761_01099	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
RT761_01116	COG1929	Belongs to the glycerate kinase type-1 family
RT761_01117	COG0497	DNA recombination
RT761_01120	COG2801	Transposase and inactivated derivatives
RT761_01120	COG3415	Transposase
RT761_01124	COG0668	transmembrane transport
RT761_01125	COG2222	sugar isomerase
RT761_01126	COG0737	Belongs to the 5'-nucleotidase family
RT761_01134	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
RT761_01136	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
RT761_01142	COG1063	alcohol dehydrogenase
RT761_01144	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
RT761_01146	COG0803	Belongs to the bacterial solute-binding protein 9 family
RT761_01147	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RT761_01149	COG1175	transmembrane transport
RT761_01153	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
RT761_01154	COG0404	The glycine cleavage system catalyzes the degradation of glycine
RT761_01155	COG0509	glycine decarboxylation via glycine cleavage system
RT761_01156	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RT761_01157	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RT761_01158	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
RT761_01159	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RT761_01162	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
RT761_01163	COG0673	inositol 2-dehydrogenase activity
RT761_01166	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RT761_01170	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
RT761_01173	COG1175	transmembrane transport
RT761_01175	COG3842	ATPase activity
RT761_01176	COG3842	ATPase activity
RT761_01177	COG1063	alcohol dehydrogenase
RT761_01178	COG3344	reverse transcriptase
RT761_01182	COG1070	Carbohydrate kinase
RT761_01183	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
RT761_01186	COG1105	Belongs to the carbohydrate kinase PfkB family
RT761_01187	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
RT761_01189	COG1472	Belongs to the glycosyl hydrolase 3 family
RT761_01190	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RT761_01191	COG1970	mechanosensitive ion channel activity
RT761_01193	COG4659	FMN binding
RT761_01195	COG2816	NAD+ diphosphatase activity
RT761_01197	COG1028	Short-chain dehydrogenase reductase Sdr
RT761_01198	COG1129	ABC transporter
RT761_01199	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_01200	COG1879	ABC-type sugar transport system periplasmic component
RT761_01203	COG2246	polysaccharide biosynthetic process
RT761_01204	COG0463	Glycosyl transferase, family 2
RT761_01208	COG1609	Transcriptional regulator
RT761_01219	COG3328	transposase activity
RT761_01223	COG3328	transposase activity
RT761_01227	COG0166	Belongs to the GPI family
RT761_01228	COG0697	spore germination
RT761_01229	COG0300	oxidoreductase activity
RT761_01230	COG1063	alcohol dehydrogenase
RT761_01234	COG1175	transmembrane transport
RT761_01239	COG0673	inositol 2-dehydrogenase activity
RT761_01240	COG1129	ABC transporter
RT761_01241	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_01243	COG0588	phosphoglycerate mutase activity
RT761_01249	COG0006	proline dipeptidase activity
RT761_01250	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
RT761_01251	COG1940	carbohydrate kinase activity
RT761_01253	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
RT761_01254	COG1879	ABC-type sugar transport system periplasmic component
RT761_01256	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_01258	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
RT761_01269	COG2033	superoxide reductase activity
RT761_01270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RT761_01271	COG0205	6-phosphofructokinase activity
RT761_01275	COG0235	Class ii aldolase
RT761_01276	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
RT761_01277	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
RT761_01285	COG1175	transmembrane transport
RT761_01286	COG0395	ABC-type sugar transport system, permease component
RT761_01287	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
RT761_01288	COG0681	Belongs to the peptidase S26 family
RT761_01289	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
RT761_01292	COG0191	fructose-bisphosphate aldolase activity
RT761_01293	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RT761_01295	COG2801	Transposase and inactivated derivatives
RT761_01295	COG3415	Transposase
RT761_01302	COG1126	abc transporter atp-binding protein
RT761_01303	COG0765	amino acid transport
RT761_01304	COG3876	Protein conserved in bacteria
RT761_01305	COG1971	Probably functions as a manganese efflux pump
RT761_01306	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
RT761_01306	COG0731	radical SAM domain protein
RT761_01307	COG1194	a g-specific adenine glycosylase
RT761_01309	COG0646	methionine synthase
RT761_01309	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
RT761_01313	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_01315	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_01322	COG0318	PFAM AMP-dependent synthetase and ligase
RT761_01323	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
RT761_01324	COG0436	Aminotransferase
RT761_01325	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
RT761_01326	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
RT761_01329	COG0205	6-phosphofructokinase activity
RT761_01330	COG0483	inositol monophosphate 1-phosphatase activity
RT761_01333	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
RT761_01336	COG1129	ABC transporter
RT761_01337	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_01338	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_01340	COG1028	Short-chain dehydrogenase reductase Sdr
RT761_01342	COG2852	Protein conserved in bacteria
RT761_01345	COG2199	diguanylate cyclase activity
RT761_01345	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
RT761_01346	COG2226	methyltransferase
RT761_01347	COG0735	belongs to the Fur family
RT761_01348	COG0753	catalase activity
RT761_01349	COG2832	Protein of unknown function (DUF454)
RT761_01356	COG1175	transmembrane transport
RT761_01357	COG0395	ABC-type sugar transport system, permease component
RT761_01363	COG3547	Transposase (IS116 IS110 IS902 family)
RT761_01375	COG1175	transmembrane transport
RT761_01376	COG0395	ABC-type sugar transport system, permease component
RT761_01377	COG1175	transmembrane transport
RT761_01378	COG0395	ABC-type sugar transport system, permease component
RT761_01379	COG1653	transport
RT761_01380	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
RT761_01382	COG3328	transposase activity
RT761_01386	COG0738	Major facilitator superfamily
RT761_01393	COG1764	response to oxidative stress
RT761_01396	COG3415	Transposase
RT761_01396	COG2801	Transposase and inactivated derivatives
RT761_01399	COG2239	Acts as a magnesium transporter
RT761_01404	COG1598	PFAM Uncharacterised protein family UPF0150
RT761_01418	COG4584	PFAM Integrase catalytic
RT761_01419	COG1484	DNA-dependent DNA replication
RT761_01427	COG4974	Belongs to the 'phage' integrase family
RT761_01433	COG0006	proline dipeptidase activity
RT761_01435	COG1129	ABC transporter
RT761_01436	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_01441	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_01445	COG1940	carbohydrate kinase activity
RT761_01446	COG0673	inositol 2-dehydrogenase activity
RT761_01447	COG1028	Short-chain dehydrogenase reductase Sdr
RT761_01449	COG1175	transmembrane transport
RT761_01450	COG0395	ABC-type sugar transport system, permease component
RT761_01453	COG1879	ABC-type sugar transport system periplasmic component
RT761_01454	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_01456	COG1879	ABC-type sugar transport system periplasmic component
RT761_01457	COG1129	ABC transporter
RT761_01458	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_01460	COG1979	alcohol dehydrogenase
RT761_01461	COG1773	rubredoxin
RT761_01461	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RT761_01464	COG4585	Histidine kinase
RT761_01465	COG2197	response regulator
RT761_01466	COG0546	phosphoglycolate phosphatase activity
RT761_01471	COG3328	transposase activity
RT761_01472	COG1598	PFAM Uncharacterised protein family UPF0150
RT761_01480	COG0019	diaminopimelate decarboxylase activity
RT761_01482	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
RT761_01483	COG0436	Aminotransferase
RT761_01484	COG0527	aspartate kinase activity
RT761_01485	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RT761_01486	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
RT761_01487	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
RT761_01488	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
RT761_01489	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RT761_01490	COG0137	argininosuccinate synthase activity
RT761_01491	COG0165	Argininosuccinate lyase
RT761_01492	COG0174	glutamine synthetase
RT761_01493	COG0445	tRNA wobble uridine modification
RT761_01494	COG1446	asparaginase
RT761_01499	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
RT761_01500	COG0352	thiamine-phosphate diphosphorylase activity
RT761_01501	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
RT761_01502	COG0352	thiamine-phosphate diphosphorylase activity
RT761_01502	COG0351	phosphomethylpyrimidine kinase
RT761_01503	COG0667	Aldo Keto reductase
RT761_01504	COG3415	Transposase
RT761_01504	COG2801	Transposase and inactivated derivatives
RT761_01507	COG2720	vancomycin resistance protein
RT761_01508	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RT761_01509	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
RT761_01510	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RT761_01511	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RT761_01512	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
RT761_01513	COG3118	belongs to the thioredoxin family
RT761_01516	COG1129	ABC transporter
RT761_01517	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_01522	COG1067	ATP-dependent peptidase activity
RT761_01524	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
RT761_01525	COG0443	Heat shock 70 kDa protein
RT761_01526	COG0484	heat shock protein binding
RT761_01527	COG1385	rRNA (uridine-N3-)-methyltransferase activity
RT761_01528	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RT761_01531	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RT761_01532	COG0371	Dehydrogenase
RT761_01534	COG1032	radical SAM domain protein
RT761_01536	COG0505	Belongs to the CarA family
RT761_01537	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
RT761_01540	COG1013	pyruvate-flavodoxin oxidoreductase activity
RT761_01543	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
RT761_01545	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
RT761_01546	COG0151	Belongs to the GarS family
RT761_01547	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
RT761_01548	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
RT761_01549	COG1573	uracil-dna glycosylase
RT761_01552	COG3854	ATPases associated with a variety of cellular activities
RT761_01553	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
RT761_01554	COG3870	Protein conserved in bacteria
RT761_01556	COG1774	PSP1 C-terminal conserved region
RT761_01561	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
RT761_01562	COG0573	inorganic phosphate transmembrane transporter activity
RT761_01563	COG0581	inorganic phosphate transmembrane transporter activity
RT761_01564	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RT761_01566	COG0811	peptide transport
RT761_01567	COG0848	biopolymer transport protein
RT761_01568	COG1470	cell adhesion involved in biofilm formation
RT761_01570	COG4974	Belongs to the 'phage' integrase family
RT761_01571	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
RT761_01573	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
RT761_01576	COG1070	Carbohydrate kinase
RT761_01578	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RT761_01580	COG4120	Belongs to the binding-protein-dependent transport system permease family
RT761_01581	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
RT761_01582	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
RT761_01584	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
RT761_01585	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
RT761_01592	COG0495	leucyl-tRNA aminoacylation
RT761_01593	COG1596	polysaccharide export
RT761_01593	COG1555	photosystem II stabilization
RT761_01594	COG1302	Protein conserved in bacteria
RT761_01595	COG0828	Belongs to the bacterial ribosomal protein bS21 family
RT761_01597	COG1702	phosphate starvation-inducible protein PhoH
RT761_01598	COG1480	7TM receptor with intracellular HD hydrolase
RT761_01599	COG0295	cytidine deaminase activity
RT761_01600	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
RT761_01601	COG1381	Involved in DNA repair and RecF pathway recombination
RT761_01602	COG0752	glycyl-tRNA synthetase alpha subunit
RT761_01603	COG0751	glycine-tRNA ligase activity
RT761_01604	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
RT761_01605	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RT761_01605	COG0574	Belongs to the PEP-utilizing enzyme family
RT761_01606	COG0232	Belongs to the dGTPase family. Type 2 subfamily
RT761_01607	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
RT761_01608	COG0358	DNA primase activity
RT761_01609	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
RT761_01614	COG3437	response regulator, receiver
RT761_01620	COG3706	GGDEF domain
RT761_01622	COG3547	Transposase (IS116 IS110 IS902 family)
RT761_01630	COG0395	ABC-type sugar transport system, permease component
RT761_01631	COG1175	transmembrane transport
RT761_01634	COG1609	Transcriptional regulator
RT761_01638	COG1522	sequence-specific DNA binding
RT761_01642	COG1028	Short-chain dehydrogenase reductase Sdr
RT761_01643	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
RT761_01646	COG1720	tRNA m6t6A37 methyltransferase activity
RT761_01656	COG1484	DNA-dependent DNA replication
RT761_01657	COG4584	PFAM Integrase catalytic
RT761_01659	COG0395	ABC-type sugar transport system, permease component
RT761_01662	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
RT761_01665	COG1125	glycine betaine transport
RT761_01665	COG0517	IMP dehydrogenase activity
RT761_01666	COG1732	Glycine betaine
RT761_01669	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RT761_01671	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RT761_01673	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
RT761_01674	COG2183	response to ionizing radiation
RT761_01676	COG1278	Cold shock
RT761_01678	COG0488	(ABC) transporter
RT761_01680	COG0318	PFAM AMP-dependent synthetase and ligase
RT761_01681	COG0039	L-malate dehydrogenase activity
RT761_01684	COG1028	Short-chain dehydrogenase reductase Sdr
RT761_01691	COG0012	GTP binding
RT761_01693	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
RT761_01706	COG1074	ATP-dependent DNA helicase activity
RT761_01707	COG0395	ABC-type sugar transport system, permease component
RT761_01708	COG1175	transmembrane transport
RT761_01710	COG1129	ABC transporter
RT761_01712	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_01713	COG1070	Carbohydrate kinase
RT761_01714	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
RT761_01715	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
RT761_01717	COG0438	transferase activity, transferring glycosyl groups
RT761_01722	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_01723	COG2186	Transcriptional regulator
RT761_01724	COG1082	Xylose isomerase domain protein TIM barrel
RT761_01727	COG2086	electron transfer activity
RT761_01728	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
RT761_01729	COG0277	FAD linked oxidase domain protein
RT761_01730	COG1132	(ABC) transporter
RT761_01731	COG1132	(ABC) transporter
RT761_01733	COG0133	tryptophan synthase activity
RT761_01734	COG0159	tryptophan synthase activity
RT761_01736	COG1129	ABC transporter
RT761_01737	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_01738	COG1070	Carbohydrate kinase
RT761_01740	COG3548	integral membrane protein
RT761_01744	COG2059	Chromate
RT761_01747	COG0395	ABC-type sugar transport system, permease component
RT761_01750	COG5598	trimethylamine methyltransferase
RT761_01751	COG3622	Belongs to the hyi family
RT761_01752	COG1940	carbohydrate kinase activity
RT761_01753	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
RT761_01757	COG1129	ABC transporter
RT761_01758	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_01759	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_01766	COG1136	(ABC) transporter
RT761_01768	COG1215	transferase activity, transferring glycosyl groups
RT761_01773	COG2342	PFAM TM1410 hypothetical-related protein
RT761_01775	COG1030	water channel activity
RT761_01776	COG4864	UPF0365 protein
RT761_01778	COG0395	ABC-type sugar transport system, permease component
RT761_01779	COG1175	transmembrane transport
RT761_01781	COG0246	Mannitol dehydrogenase
RT761_01784	COG0346	lactoylglutathione lyase activity
RT761_01787	COG0384	phenazine biosynthesis protein PhzF
RT761_01794	COG1609	Transcriptional regulator
RT761_01795	COG0006	proline dipeptidase activity
RT761_01797	COG1175	transmembrane transport
RT761_01798	COG0395	ABC-type sugar transport system, permease component
RT761_01801	COG1028	Short-chain dehydrogenase reductase Sdr
RT761_01804	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
RT761_01807	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
RT761_01810	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
RT761_01816	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
RT761_01824	COG0641	radical SAM
RT761_01825	COG3119	arylsulfatase activity
RT761_01832	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
RT761_01833	COG0732	type I restriction modification DNA specificity domain
RT761_01837	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
RT761_01839	COG1028	Short-chain dehydrogenase reductase Sdr
RT761_01848	COG1337	RAMP superfamily
RT761_01850	COG1353	crispr-associated protein
RT761_01856	COG1484	DNA-dependent DNA replication
RT761_01857	COG4584	PFAM Integrase catalytic
RT761_01860	COG1518	maintenance of DNA repeat elements
RT761_01861	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
RT761_01862	COG4584	PFAM Integrase catalytic
RT761_01863	COG1484	DNA-dependent DNA replication
RT761_01880	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RT761_01880	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RT761_01883	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_01884	COG1129	ABC transporter
RT761_01885	COG1028	Short-chain dehydrogenase reductase Sdr
RT761_01886	COG1879	ABC-type sugar transport system periplasmic component
RT761_01894	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
RT761_01895	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RT761_01895	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
RT761_01899	COG0095	Lipoate-protein ligase
RT761_01901	COG5002	protein histidine kinase activity
RT761_01901	COG5001	Diguanylate cyclase
RT761_01901	COG3447	MASE1 domain protein
RT761_01906	COG2135	peptidase activity
RT761_01913	COG1175	transmembrane transport
RT761_01914	COG0395	ABC-type sugar transport system, permease component
RT761_01915	COG1609	Transcriptional regulator
RT761_01916	COG0006	proline dipeptidase activity
RT761_01917	COG0395	ABC-type sugar transport system, permease component
RT761_01919	COG0438	transferase activity, transferring glycosyl groups
RT761_01923	COG2199	diguanylate cyclase activity
RT761_01923	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
RT761_01924	COG1472	Belongs to the glycosyl hydrolase 3 family
RT761_01925	COG4608	Belongs to the ABC transporter superfamily
RT761_01926	COG0444	Belongs to the ABC transporter superfamily
RT761_01928	COG0601	transmembrane transport
RT761_01930	COG1609	Transcriptional regulator
RT761_01931	COG4690	dipeptidase activity
RT761_01935	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_01936	COG1129	ABC transporter
RT761_01938	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_01939	COG1129	ABC transporter
RT761_01945	COG1454	alcohol dehydrogenase
RT761_01947	COG0217	transcriptional regulatory protein
RT761_01948	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
RT761_01949	COG0632	four-way junction helicase activity
RT761_01950	COG2255	four-way junction helicase activity
RT761_01951	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
RT761_01953	COG2385	sporulation resulting in formation of a cellular spore
RT761_01954	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
RT761_01955	COG0343	queuine tRNA-ribosyltransferase activity
RT761_01956	COG1862	Preprotein translocase
RT761_01957	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RT761_01958	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RT761_01959	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
RT761_01959	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
RT761_01960	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
RT761_01961	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
RT761_01962	COG1490	D-aminoacyl-tRNA deacylase activity
RT761_01964	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RT761_01965	COG3707	response regulator
RT761_01966	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RT761_01967	COG1121	(ABC) transporter
RT761_01975	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_01976	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_01977	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
RT761_01979	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
RT761_01980	COG0785	Cytochrome C biogenesis protein
RT761_01986	COG0704	Plays a role in the regulation of phosphate uptake
RT761_01989	COG1063	alcohol dehydrogenase
RT761_01990	COG1063	alcohol dehydrogenase
RT761_01991	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
RT761_01994	COG0037	tRNA processing
RT761_01996	COG0037	tRNA processing
RT761_01997	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
RT761_01998	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RT761_02000	COG0569	domain protein
RT761_02003	COG2359	stage V sporulation protein S
RT761_02005	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
RT761_02009	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
RT761_02009	COG2199	diguanylate cyclase activity
RT761_02015	COG1879	ABC-type sugar transport system periplasmic component
RT761_02017	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_02018	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_02019	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
RT761_02023	COG0110	maltose O-acetyltransferase activity
RT761_02025	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
RT761_02027	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
RT761_02028	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
RT761_02029	COG0124	histidyl-tRNA synthetase
RT761_02032	COG2321	neutral zinc metallopeptidase
RT761_02034	COG2390	Transcriptional regulator
RT761_02035	COG1653	transport
RT761_02043	COG1063	alcohol dehydrogenase
RT761_02047	COG0534	Mate efflux family protein
RT761_02048	COG1331	Highly conserved protein containing a thioredoxin domain
RT761_02050	COG0028	Belongs to the TPP enzyme family
RT761_02051	COG0747	negative chemotaxis
RT761_02053	COG1121	(ABC) transporter
RT761_02054	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RT761_02055	COG4822	anaerobic cobalamin biosynthetic process
RT761_02060	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
RT761_02062	COG1797	cobyrinic acid a,c-diamide synthase activity
RT761_02063	COG0018	arginyl-trna synthetase
RT761_02064	COG0504	CTP synthase activity
RT761_02066	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
RT761_02068	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
RT761_02069	COG0254	rRNA binding
RT761_02070	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
RT761_02071	COG3872	metal-dependent enzyme
RT761_02072	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
RT761_02074	COG0698	ribose 5-phosphate isomerase
RT761_02076	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RT761_02077	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
RT761_02078	COG0355	proton-transporting ATP synthase activity, rotational mechanism
RT761_02079	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
RT761_02080	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
RT761_02083	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
RT761_02085	COG0356	it plays a direct role in the translocation of protons across the membrane
RT761_02100	COG3328	transposase activity
RT761_02102	COG3264	Mechanosensitive ion channel
RT761_02102	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
RT761_02106	COG0667	Aldo Keto reductase
RT761_02108	COG0395	ABC-type sugar transport system, permease component
RT761_02111	COG4821	SIS domain
RT761_02112	COG2188	Transcriptional regulator
RT761_02113	COG4821	SIS domain
RT761_02114	COG1070	Carbohydrate kinase
RT761_02115	COG0363	glucosamine-6-phosphate deaminase activity
RT761_02116	COG2271	Major facilitator Superfamily
RT761_02118	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RT761_02121	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
RT761_02122	COG2239	Acts as a magnesium transporter
RT761_02123	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
RT761_02129	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RT761_02131	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
RT761_02133	COG1940	carbohydrate kinase activity
RT761_02136	COG1968	undecaprenyl-diphosphatase activity
RT761_02139	COG0009	L-threonylcarbamoyladenylate synthase
RT761_02144	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
RT761_02145	COG4145	pantothenate transmembrane transporter activity
RT761_02146	COG1063	alcohol dehydrogenase
RT761_02150	COG0395	ABC-type sugar transport system, permease component
RT761_02153	COG1192	Involved in chromosome partitioning
RT761_02154	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
RT761_02156	COG0741	lytic transglycosylase activity
RT761_02157	COG1796	DNA polymerase
RT761_02157	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
RT761_02158	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
RT761_02159	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
RT761_02160	COG0066	3-isopropylmalate dehydratase activity
RT761_02161	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
RT761_02162	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
RT761_02163	COG2116	formate transmembrane transporter activity
RT761_02164	COG5012	cobalamin binding
RT761_02165	COG2759	Belongs to the formate--tetrahydrofolate ligase family
RT761_02166	COG0492	ferredoxin-NADP+ reductase activity
RT761_02177	COG0285	dihydrofolate synthase activity
RT761_02180	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RT761_02181	COG0047	phosphoribosylformylglycinamidine synthase activity
RT761_02182	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RT761_02183	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
RT761_02184	COG0655	NAD(P)H dehydrogenase (quinone) activity
RT761_02186	COG1269	ATP hydrolysis coupled proton transport
RT761_02187	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
RT761_02191	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
RT761_02192	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
RT761_02193	COG1394	ATPase activity, coupled to movement of substances
RT761_02194	COG3415	Transposase
RT761_02194	COG2801	Transposase and inactivated derivatives
RT761_02199	COG3459	Glycosyltransferase 36 associated
RT761_02201	COG0395	ABC-type sugar transport system, permease component
RT761_02203	COG1609	Transcriptional regulator
RT761_02204	COG1349	DNA-binding transcription factor activity
RT761_02205	COG1175	transmembrane transport
RT761_02206	COG0395	ABC-type sugar transport system, permease component
RT761_02209	COG1349	DNA-binding transcription factor activity
RT761_02210	COG1653	transport
RT761_02211	COG1175	transmembrane transport
RT761_02212	COG0395	ABC-type sugar transport system, permease component
RT761_02215	COG1129	ABC transporter
RT761_02216	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_02217	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_02223	COG0395	ABC-type sugar transport system, permease component
RT761_02224	COG1175	transmembrane transport
RT761_02225	COG1653	transport
RT761_02227	COG2188	Transcriptional regulator
RT761_02229	COG1175	transmembrane transport
RT761_02230	COG0395	ABC-type sugar transport system, permease component
RT761_02231	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
RT761_02232	COG1609	Transcriptional regulator
RT761_02235	COG0395	ABC-type sugar transport system, permease component
RT761_02237	COG1882	Formate acetyltransferase
RT761_02238	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
RT761_02239	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RT761_02240	COG0022	dehydrogenase e1 component
RT761_02243	COG1484	DNA-dependent DNA replication
RT761_02244	COG4584	PFAM Integrase catalytic
RT761_02247	COG0420	3'-5' exonuclease activity
RT761_02248	COG4717	serine-type aminopeptidase activity
RT761_02250	COG2723	6-phospho-beta-galactosidase activity
RT761_02251	COG3534	alpha-L-arabinofuranosidase
RT761_02253	COG0444	Belongs to the ABC transporter superfamily
RT761_02255	COG0395	ABC-type sugar transport system, permease component
RT761_02256	COG1175	transmembrane transport
RT761_02258	COG0673	inositol 2-dehydrogenase activity
RT761_02263	COG1175	transmembrane transport
RT761_02264	COG0395	ABC-type sugar transport system, permease component
RT761_02295	COG1525	nuclease
RT761_02297	COG1484	DNA-dependent DNA replication
RT761_02298	COG4584	PFAM Integrase catalytic
RT761_02301	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
RT761_02309	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
RT761_02311	COG1943	Transposase
RT761_02312	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
RT761_02313	COG1196	nuclear chromosome segregation
RT761_02316	COG1943	Transposase
RT761_02318	COG3547	Transposase (IS116 IS110 IS902 family)
RT761_02323	COG1940	carbohydrate kinase activity
RT761_02324	COG2222	sugar isomerase
RT761_02329	COG1175	transmembrane transport
RT761_02330	COG0395	ABC-type sugar transport system, permease component
RT761_02333	COG2188	Transcriptional regulator
RT761_02338	COG1175	transmembrane transport
RT761_02339	COG0395	ABC-type sugar transport system, permease component
RT761_02340	COG4692	amylo-alpha-1,6-glucosidase activity
RT761_02342	COG2362	D-Aminopeptidase
RT761_02347	COG1070	Carbohydrate kinase
RT761_02348	COG0434	BtpA family
RT761_02350	COG1082	Xylose isomerase domain protein TIM barrel
RT761_02351	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_02352	COG4211	Belongs to the binding-protein-dependent transport system permease family
RT761_02353	COG1129	ABC transporter
RT761_02357	COG1175	transmembrane transport
RT761_02358	COG0395	ABC-type sugar transport system, permease component
RT761_02360	COG2199	diguanylate cyclase activity
RT761_02360	COG2200	EAL domain
RT761_02360	COG2203	Gaf domain
RT761_02364	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
RT761_02365	COG2133	pyrroloquinoline quinone binding
RT761_02367	COG2801	Transposase and inactivated derivatives
RT761_02367	COG3415	Transposase
RT761_02371	COG0719	Fe-S assembly protein
RT761_02374	COG1175	transmembrane transport
RT761_02375	COG0395	ABC-type sugar transport system, permease component
RT761_02376	COG0445	tRNA wobble uridine modification
RT761_02380	COG1175	transmembrane transport
RT761_02381	COG0395	ABC-type sugar transport system, permease component
RT761_02384	COG0445	tRNA wobble uridine modification
RT761_02387	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
RT761_02389	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RT761_02390	COG0395	ABC-type sugar transport system, permease component
RT761_02391	COG1175	transmembrane transport
RT761_02395	COG5001	Diguanylate cyclase
RT761_02399	COG3162	membrane
RT761_02401	COG0456	acetyltransferase
RT761_02402	COG1063	alcohol dehydrogenase
RT761_02408	COG2309	aminopeptidase activity
RT761_02410	COG3437	response regulator, receiver
RT761_02411	COG0673	inositol 2-dehydrogenase activity
RT761_02413	COG0823	Involved in the tonB-independent uptake of proteins
RT761_02418	COG0395	ABC-type sugar transport system, permease component
RT761_02419	COG1175	transmembrane transport
RT761_02429	COG0658	competence protein
RT761_02429	COG2333	competence protein COMEC
RT761_02433	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
RT761_02434	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
RT761_02436	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
RT761_02437	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
RT761_02439	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
RT761_02440	COG0736	holo-[acyl-carrier-protein] synthase activity
RT761_02441	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
RT761_02441	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
RT761_02442	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RT761_02443	COG0802	atpase or kinase
RT761_02444	COG1214	PFAM Peptidase M22, glycoprotease
RT761_02446	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
RT761_02447	COG0459	protein refolding
RT761_02449	COG0516	GMP reductase activity
RT761_02450	COG0519	Catalyzes the synthesis of GMP from XMP
RT761_02450	COG0518	GMP synthase (glutamine-hydrolyzing) activity
RT761_02451	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
RT761_02452	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
RT761_02453	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
RT761_02454	COG0154	amidase activity
RT761_02455	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
RT761_02459	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RT761_02459	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RT761_02460	COG0297	glycogen (starch) synthase activity
RT761_02461	COG0237	dephospho-CoA kinase activity
RT761_02462	COG0556	nucleotide-excision repair
RT761_02463	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
RT761_02464	COG0322	excinuclease ABC activity
RT761_02465	COG1481	regulation of sporulation
RT761_02466	COG3842	ATPase activity
RT761_02468	COG0149	triose-phosphate isomerase activity
RT761_02472	COG0601	transmembrane transport
RT761_02473	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RT761_02474	COG0444	Belongs to the ABC transporter superfamily
RT761_02475	COG4608	Belongs to the ABC transporter superfamily
RT761_02476	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
RT761_02477	COG0291	Belongs to the bacterial ribosomal protein bL35 family
RT761_02478	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
RT761_02479	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
RT761_02480	COG0072	phenylalanine-tRNA ligase activity
RT761_02482	COG1193	negative regulation of DNA recombination
RT761_02483	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
RT761_02485	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
RT761_02486	COG0195	Participates in both transcription termination and antitermination
RT761_02487	COG2740	Nucleic-acid-binding protein implicated in transcription termination
RT761_02488	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
RT761_02490	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
RT761_02492	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
RT761_02493	COG0196	riboflavin kinase activity
RT761_02494	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
RT761_02495	COG1185	polyribonucleotide nucleotidyltransferase activity
RT761_02496	COG1674	ftsk spoiiie
RT761_02499	COG1546	Belongs to the CinA family
RT761_02499	COG1058	Belongs to the CinA family
RT761_02501	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
RT761_02503	COG1418	mRNA catabolic process
RT761_02504	COG1692	metallophosphoesterase
RT761_02505	COG2359	stage V sporulation protein S
RT761_02506	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RT761_02507	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
RT761_02509	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
RT761_02511	COG0442	prolyl-tRNA aminoacylation
RT761_02512	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
RT761_02513	COG0750	zinc metalloprotease
RT761_02514	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
RT761_02515	COG4589	Belongs to the CDS family
RT761_02516	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
RT761_02517	COG0233	cytoplasmic translational termination
RT761_02518	COG0528	UMP kinase activity
RT761_02520	COG0052	Belongs to the universal ribosomal protein uS2 family
RT761_02521	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
RT761_02522	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
RT761_02524	COG1160	GTP binding
RT761_02525	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
RT761_02526	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
RT761_02527	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
RT761_02528	COG4401	Chorismate mutase type I
RT761_02530	COG1187	pseudouridine synthase activity
RT761_02531	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
RT761_02533	COG0180	Tryptophanyl-tRNA synthetase
RT761_02534	COG0617	tRNA 3'-terminal CCA addition
RT761_02534	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
RT761_02534	COG3620	sequence-specific DNA binding
RT761_02535	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
RT761_02536	COG0494	nUDIX hydrolase
RT761_02537	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
RT761_02537	COG0617	tRNA 3'-terminal CCA addition
RT761_02537	COG0517	IMP dehydrogenase activity
RT761_02540	COG0674	pyruvate-flavodoxin oxidoreductase activity
RT761_02540	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
RT761_02542	COG0497	DNA recombination
RT761_02543	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
RT761_02544	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
RT761_02545	COG0142	geranyltranstransferase activity
RT761_02546	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RT761_02548	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
RT761_02550	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
RT761_02551	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
RT761_02552	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
RT761_02563	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
RT761_02564	COG4969	Belongs to the N-Me-Phe pilin family
RT761_02565	COG1459	type II secretion system
RT761_02568	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
RT761_02569	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
RT761_02570	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
RT761_02571	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
RT761_02572	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
RT761_02573	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
RT761_02574	COG1606	tRNA processing
RT761_02575	COG2183	response to ionizing radiation
RT761_02575	COG0539	negative regulation of cytoplasmic translation
RT761_02576	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
RT761_02577	COG0124	histidyl-tRNA synthetase
RT761_02578	COG1285	pathogenesis
RT761_02579	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RT761_02580	COG0138	bifunctional purine biosynthesis protein purh
RT761_02581	COG1069	ribulokinase activity
RT761_02583	COG0126	phosphoglycerate kinase activity
RT761_02586	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RT761_02587	COG0481	GTPase activity
RT761_02591	COG0101	tRNA pseudouridine synthase activity
RT761_02592	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
RT761_02593	COG1122	ATPase activity
RT761_02594	COG1122	ATPase activity
RT761_02595	COG0203	ribosomal protein L17
RT761_02596	COG0202	RNA polymerase activity
RT761_02597	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
RT761_02598	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
RT761_02599	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
RT761_02600	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
RT761_02602	COG0563	adenylate kinase activity
RT761_02603	COG0201	protein transport
RT761_02604	COG0200	Binds to the 23S rRNA
RT761_02605	COG1841	ribosomal large subunit assembly
RT761_02607	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
RT761_02608	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
RT761_02609	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
RT761_02610	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
RT761_02612	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
RT761_02613	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
RT761_02614	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
RT761_02615	COG0255	Belongs to the universal ribosomal protein uL29 family
RT761_02616	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
RT761_02617	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
RT761_02618	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
RT761_02619	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
RT761_02620	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
RT761_02621	COG0089	rRNA binding
RT761_02622	COG0088	Forms part of the polypeptide exit tunnel
RT761_02623	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
RT761_02624	COG0051	transcription antitermination factor activity, RNA binding
RT761_02625	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
RT761_02626	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
RT761_02627	COG0049	tRNA binding
RT761_02628	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
RT761_02629	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
RT761_02629	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
RT761_02630	COG0085	RNA polymerase activity
RT761_02631	COG1355	regulation of microtubule-based process
RT761_02636	COG0071	Belongs to the small heat shock protein (HSP20) family
RT761_02642	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
RT761_02643	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
RT761_02644	COG0673	inositol 2-dehydrogenase activity
RT761_02646	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
RT761_02648	COG0287	Prephenate dehydrogenase
RT761_02649	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
RT761_02650	COG0820	rRNA (adenine-C2-)-methyltransferase activity
RT761_02652	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
RT761_02653	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
RT761_02659	COG1598	PFAM Uncharacterised protein family UPF0150
RT761_02671	COG4584	PFAM Integrase catalytic
RT761_02672	COG4584	PFAM Integrase catalytic
RT761_02674	COG1484	DNA-dependent DNA replication
RT761_02683	COG2197	response regulator
RT761_02684	COG4585	Histidine kinase
RT761_02686	COG2197	response regulator
RT761_02689	COG2801	Transposase and inactivated derivatives
RT761_02689	COG3415	Transposase
RT761_02697	COG1129	ABC transporter
RT761_02698	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_02699	COG1172	Belongs to the binding-protein-dependent transport system permease family
RT761_02701	COG0747	negative chemotaxis
RT761_02702	COG0601	transmembrane transport
RT761_02703	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RT761_02704	COG0444	Belongs to the ABC transporter superfamily
RT761_02705	COG4608	Belongs to the ABC transporter superfamily
RT761_02707	COG0460	homoserine dehydrogenase
RT761_02709	COG0765	amino acid transport
RT761_02710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RT761_02711	COG0305	Participates in initiation and elongation during chromosome replication
RT761_02712	COG0359	binds to the 23S rRNA
RT761_02714	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
RT761_02716	COG0360	Binds together with S18 to 16S ribosomal RNA
RT761_02717	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
RT761_02718	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
RT761_02719	COG0799	negative regulation of ribosome biogenesis
RT761_02720	COG1316	TRANSCRIPTIONal
RT761_02722	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
RT761_02723	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
RT761_02724	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
RT761_02725	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
RT761_02726	COG0211	Belongs to the bacterial ribosomal protein bL27 family
RT761_02727	COG0261	This protein binds to 23S rRNA in the presence of protein L20
RT761_02728	COG1530	ribonuclease E activity
RT761_02731	COG0772	Belongs to the SEDS family
RT761_02732	COG0768	penicillin binding
RT761_02734	COG1792	Involved in formation and maintenance of cell shape
RT761_02735	COG1477	protein flavinylation
RT761_02737	COG2078	PFAM AMMECR1 domain protein
RT761_02737	COG3885	ferrous iron binding
RT761_02744	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RT761_02744	COG4191	Histidine kinase
RT761_02746	COG0542	response to heat
RT761_02747	COG0789	Transcriptional regulator
RT761_02752	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
RT761_02753	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RT761_02755	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
RT761_02756	COG1085	galactose-1-phosphate uridylyltransferase
RT761_02758	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
RT761_02761	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
RT761_02764	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
RT761_02765	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
RT761_02767	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RT761_02768	COG0647	UMP catabolic process
RT761_02769	COG1131	(ABC) transporter
RT761_02773	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RT761_02774	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
RT761_02778	COG1691	(AIR) carboxylase
RT761_02779	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
RT761_02782	COG0411	ABC transporter
RT761_02784	COG0559	Belongs to the binding-protein-dependent transport system permease family
RT761_02791	COG1659	Linocin_M18 bacteriocin protein
RT761_02792	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
RT761_02795	COG2217	Heavy metal translocating P-type atpase
RT761_02796	COG2217	Heavy metal translocating P-type atpase
RT761_02797	COG1136	(ABC) transporter
RT761_02798	COG4591	ABC-type transport system involved in lipoprotein release permease component
RT761_02800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RT761_02801	COG3189	MarR family transcriptional regulator