locus-tag	class	description
OZN62_00015	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OZN62_00045	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OZN62_00050	COG0137	argininosuccinate synthase activity
OZN62_00060	COG0534	Mate efflux family protein
OZN62_00065	COG1137	ATPase activity
OZN62_00070	COG2133	pyrroloquinoline quinone binding
OZN62_00075	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OZN62_00085	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OZN62_00095	COG4221	oxidoreductase activity
OZN62_00100	COG2133	pyrroloquinoline quinone binding
OZN62_00130	COG2311	Membrane
OZN62_00135	COG0820	rRNA (adenine-C2-)-methyltransferase activity
OZN62_00175	COG0741	lytic transglycosylase activity
OZN62_00180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OZN62_00190	COG1073	alpha beta
OZN62_00195	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OZN62_00220	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OZN62_00230	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OZN62_00245	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OZN62_00250	COG3153	acetyltransferase
OZN62_00250	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OZN62_00255	COG0538	isocitrate dehydrogenase activity
OZN62_00265	COG1960	acyl-CoA dehydrogenase activity
OZN62_00270	COG1250	3-hydroxyacyl-CoA dehydrogenase
OZN62_00270	COG1024	Enoyl-CoA hydratase
OZN62_00275	COG0183	Belongs to the thiolase family
OZN62_00280	COG0318	PFAM AMP-dependent synthetase and ligase
OZN62_00325	COG2885	chlorophyll binding
OZN62_00330	COG0210	DNA helicase
OZN62_00340	COG0742	ribosomal rna small subunit methyltransferase
OZN62_00345	COG1187	pseudouridine synthase activity
OZN62_00350	COG2223	nitrite transmembrane transporter activity
OZN62_00355	COG0285	dihydrofolate synthase activity
OZN62_00360	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OZN62_00365	COG0159	tryptophan synthase activity
OZN62_00370	COG0133	tryptophan synthase activity
OZN62_00375	COG0135	phosphoribosylanthranilate isomerase activity
OZN62_00385	COG0284	orotidine-5'-phosphate decarboxylase activity
OZN62_00395	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OZN62_00405	COG2003	Belongs to the UPF0758 family
OZN62_00430	COG0356	it plays a direct role in the translocation of protons across the membrane
OZN62_00435	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OZN62_00440	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OZN62_00445	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OZN62_00450	COG2910	NAD(P)H-binding
OZN62_00455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OZN62_00465	COG0539	negative regulation of cytoplasmic translation
OZN62_00475	COG3647	Membrane
OZN62_00480	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
OZN62_00500	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OZN62_00515	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OZN62_00520	COG0228	four-way junction DNA binding
OZN62_00525	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OZN62_00545	COG0336	Belongs to the RNA methyltransferase TrmD family
OZN62_00550	COG0335	large ribosomal subunit rRNA binding
OZN62_00555	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OZN62_00565	COG2267	carboxylic ester hydrolase activity
OZN62_00590	COG0359	binds to the 23S rRNA
OZN62_00595	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OZN62_00600	COG0360	Binds together with S18 to 16S ribosomal RNA
OZN62_00610	COG2354	Protein conserved in bacteria
OZN62_00620	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OZN62_00660	COG0493	'glutamate synthase
OZN62_00665	COG5001	Diguanylate cyclase
OZN62_00665	COG3300	MHYT domain
OZN62_00670	COG5001	Diguanylate cyclase
OZN62_00670	COG3300	MHYT domain
OZN62_00675	COG0481	GTPase activity
OZN62_00720	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OZN62_00745	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OZN62_00760	COG2264	protein methyltransferase activity
OZN62_00765	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
OZN62_00770	COG1028	Short-chain dehydrogenase reductase Sdr
OZN62_00780	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
OZN62_00810	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OZN62_00830	COG1595	DNA-templated transcription, initiation
OZN62_00850	COG2321	neutral zinc metallopeptidase
OZN62_00855	COG1028	Short-chain dehydrogenase reductase Sdr
OZN62_00870	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OZN62_00880	COG1051	belongs to the nudix hydrolase family
OZN62_00885	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
OZN62_00885	COG0674	pyruvate-flavodoxin oxidoreductase activity
OZN62_00890	COG1013	pyruvate-flavodoxin oxidoreductase activity
OZN62_00895	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OZN62_00910	COG0415	Belongs to the DNA photolyase family
OZN62_00915	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OZN62_00930	COG4221	oxidoreductase activity
OZN62_00935	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
OZN62_00940	COG3047	cAMP biosynthetic process
OZN62_00990	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OZN62_01080	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OZN62_01105	COG1454	alcohol dehydrogenase
OZN62_01120	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OZN62_01140	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OZN62_01145	COG0126	phosphoglycerate kinase activity
OZN62_01160	COG3588	fructose-bisphosphate aldolase
OZN62_01165	COG0352	thiamine-phosphate diphosphorylase activity
OZN62_01170	COG4942	peptidase
OZN62_01180	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OZN62_01190	COG0483	inositol monophosphate 1-phosphatase activity
OZN62_01200	COG3273	potassium ion transport
OZN62_01200	COG0471	metal ion transport
OZN62_01210	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OZN62_01220	COG2204	response regulator
OZN62_01225	COG0385	Bile acid
OZN62_01235	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
OZN62_01240	COG0733	neurotransmitter:sodium symporter activity
OZN62_01260	COG1253	flavin adenine dinucleotide binding
OZN62_01280	COG0587	DNA-directed DNA polymerase activity
OZN62_01295	COG0745	RESPONSE REGULATOR receiver
OZN62_01300	COG0704	Plays a role in the regulation of phosphate uptake
OZN62_01305	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OZN62_01315	COG0573	inorganic phosphate transmembrane transporter activity
OZN62_01325	COG3746	phosphate-selective porin O and P
OZN62_01330	COG5002	protein histidine kinase activity
OZN62_01345	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OZN62_01365	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OZN62_01370	COG2353	YceI-like domain
OZN62_01375	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OZN62_01390	COG0028	Belongs to the TPP enzyme family
OZN62_01395	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OZN62_01400	COG0560	Phosphoserine phosphatase
OZN62_01415	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OZN62_01425	COG1722	exodeoxyribonuclease VII activity
OZN62_01430	COG0142	geranyltranstransferase activity
OZN62_01435	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OZN62_01445	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OZN62_01450	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
OZN62_01455	COG1131	(ABC) transporter
OZN62_01460	COG0842	Transport permease protein
OZN62_01470	COG0343	queuine tRNA-ribosyltransferase activity
OZN62_01475	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OZN62_01495	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OZN62_01505	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OZN62_01510	COG0698	ribose 5-phosphate isomerase
OZN62_01520	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
OZN62_01530	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OZN62_01535	COG0358	DNA primase activity
OZN62_01550	COG0505	Belongs to the CarA family
OZN62_01560	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OZN62_01590	COG0148	phosphopyruvate hydratase activity
OZN62_01600	COG0667	Aldo Keto reductase
OZN62_01605	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
OZN62_01610	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OZN62_01610	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OZN62_01615	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OZN62_01625	COG1304	FMN binding
OZN62_01650	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OZN62_01665	COG0772	Belongs to the SEDS family
OZN62_01690	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OZN62_01715	COG0288	reversible hydration of carbon dioxide
OZN62_01730	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OZN62_01735	COG2867	negative regulation of translational initiation
OZN62_01740	COG1546	Belongs to the CinA family
OZN62_01740	COG1058	Belongs to the CinA family
OZN62_01745	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
OZN62_01745	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
OZN62_01760	COG2204	response regulator
OZN62_01765	COG5000	phosphorelay sensor kinase activity
OZN62_01770	COG2204	response regulator
OZN62_01780	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OZN62_01785	COG3956	TIGRFAM MazG family protein
OZN62_01795	COG0321	lipoyl(octanoyl) transferase activity
OZN62_01795	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
OZN62_01800	COG0084	hydrolase, TatD family'
OZN62_01815	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OZN62_01820	COG1686	Belongs to the peptidase S11 family
OZN62_01830	COG2951	lytic endotransglycosylase activity
OZN62_01845	COG0784	Response regulator, receiver
OZN62_01845	COG2198	Histidine kinase
OZN62_01845	COG5002	protein histidine kinase activity
OZN62_01855	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OZN62_01860	COG1607	acyl-coa hydrolase
OZN62_01865	COG0508	dehydrogenase complex catalyzes the overall conversion of
OZN62_01880	COG0557	exoribonuclease II activity
OZN62_01885	COG2234	aminopeptidase activity
OZN62_01890	COG0339	signal peptide processing
OZN62_01895	COG0442	prolyl-tRNA aminoacylation
OZN62_01905	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OZN62_01915	COG0477	Major facilitator Superfamily
OZN62_01935	COG1752	Esterase of the alpha-beta hydrolase superfamily
OZN62_01940	COG0484	heat shock protein binding
OZN62_01945	COG0443	Heat shock 70 kDa protein
OZN62_01970	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OZN62_01975	COG1420	regulation of RNA biosynthetic process
OZN62_01980	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OZN62_01985	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OZN62_01995	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OZN62_02000	COG4974	Belongs to the 'phage' integrase family
OZN62_02005	COG0586	Pfam SNARE associated Golgi protein
OZN62_02010	COG0189	ligase activity
OZN62_02015	COG0792	nuclease activity
OZN62_02020	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OZN62_02030	COG0187	DNA topoisomerase II activity
OZN62_02055	COG3876	Protein conserved in bacteria
OZN62_02065	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OZN62_02095	COG1960	acyl-CoA dehydrogenase activity
OZN62_02100	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OZN62_02115	COG0574	Belongs to the PEP-utilizing enzyme family
OZN62_02115	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OZN62_02120	COG0751	glycine-tRNA ligase activity
OZN62_02125	COG0752	glycyl-tRNA synthetase alpha subunit
OZN62_02145	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OZN62_02155	COG0193	aminoacyl-tRNA hydrolase activity
OZN62_02175	COG0012	GTP binding
OZN62_02185	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OZN62_02205	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
OZN62_02250	COG0508	dehydrogenase complex catalyzes the overall conversion of
OZN62_02250	COG0022	dehydrogenase e1 component
OZN62_02255	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OZN62_02280	COG4771	TonB-dependent receptor
OZN62_02295	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OZN62_02300	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
OZN62_02305	COG0071	Belongs to the small heat shock protein (HSP20) family
OZN62_02310	COG0504	CTP synthase activity
OZN62_02320	COG0149	triose-phosphate isomerase activity
OZN62_02330	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OZN62_02350	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OZN62_02355	COG0134	indole-3-glycerol-phosphate synthase activity
OZN62_02360	COG0315	cyclic pyranopterin monophosphate synthase activity
OZN62_02365	COG0303	'Molybdopterin
OZN62_02370	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OZN62_02375	COG2333	competence protein COMEC
OZN62_02375	COG0658	competence protein
OZN62_02380	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OZN62_02385	COG0372	Belongs to the citrate synthase family
OZN62_02390	COG2205	protein histidine kinase activity
OZN62_02420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
OZN62_02430	COG1007	ATP synthesis coupled electron transport
OZN62_02445	COG0713	ATP synthesis coupled electron transport
OZN62_02455	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OZN62_02460	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
OZN62_02480	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
OZN62_02500	COG0649	NAD binding
OZN62_02505	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OZN62_02515	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OZN62_02520	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OZN62_02530	COG1012	belongs to the aldehyde dehydrogenase family
OZN62_02535	COG0183	Belongs to the thiolase family
OZN62_02565	COG0004	ammonium transporteR
OZN62_02595	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
OZN62_02605	COG1530	ribonuclease E activity
OZN62_02615	COG2226	methyltransferase
OZN62_02635	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
OZN62_02640	COG0367	asparagine synthase
OZN62_02665	COG3267	Type II secretory pathway component ExeA
OZN62_02665	COG3409	Peptidoglycan-binding domain 1 protein
OZN62_02695	COG0318	PFAM AMP-dependent synthetase and ligase
OZN62_02720	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OZN62_02735	COG0129	dihydroxy-acid dehydratase activity
OZN62_02745	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OZN62_02765	COG0521	Mo-molybdopterin cofactor biosynthetic process
OZN62_02780	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
OZN62_02780	COG2885	chlorophyll binding
OZN62_02800	COG1136	(ABC) transporter
OZN62_02815	COG0531	amino acid
OZN62_02825	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OZN62_02840	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OZN62_02850	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OZN62_02865	COG0653	protein targeting
OZN62_02875	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OZN62_02880	COG0483	inositol monophosphate 1-phosphatase activity
OZN62_02890	COG1074	ATP-dependent DNA helicase activity
OZN62_02900	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OZN62_02905	COG3178	'Phosphotransferase
OZN62_02910	COG0802	atpase or kinase
OZN62_02915	COG2205	protein histidine kinase activity
OZN62_02920	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
OZN62_02925	COG0678	peroxiredoxin activity
OZN62_02940	COG0302	gtp cyclohydrolase
OZN62_02945	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OZN62_02960	COG0494	nUDIX hydrolase
OZN62_02980	COG0825	malonyl-CoA metabolic process
OZN62_02985	COG4974	Belongs to the 'phage' integrase family
OZN62_03000	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OZN62_03005	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OZN62_03010	COG3104	oligopeptide transport
OZN62_03015	COG1024	Enoyl-CoA hydratase
OZN62_03025	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OZN62_03040	COG0513	Belongs to the DEAD box helicase family
OZN62_03060	COG0166	Belongs to the GPI family
OZN62_03065	COG0681	Belongs to the peptidase S26 family
OZN62_03070	COG0571	ribonuclease III activity
OZN62_03075	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OZN62_03080	COG0745	RESPONSE REGULATOR receiver
OZN62_03095	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OZN62_03095	COG1754	DNA topoisomerase type I activity
OZN62_03115	COG0758	DNA mediated transformation
OZN62_03120	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
OZN62_03125	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OZN62_03130	COG0156	8-amino-7-oxononanoate synthase activity
OZN62_03135	COG5001	Diguanylate cyclase
OZN62_03135	COG3300	MHYT domain
OZN62_03155	COG1704	LemA family
OZN62_03165	COG1899	peptidyl-lysine modification to peptidyl-hypusine
OZN62_03190	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
OZN62_03195	COG3387	PFAM Glycoside hydrolase 15-related
OZN62_03200	COG1877	trehalose-phosphatase activity
OZN62_03215	COG4771	TonB-dependent receptor
OZN62_03230	COG1136	(ABC) transporter
OZN62_03240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OZN62_03245	COG0346	lactoylglutathione lyase activity
OZN62_03290	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OZN62_03295	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OZN62_03300	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OZN62_03305	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OZN62_03310	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
OZN62_03315	COG0583	DNA-binding transcription factor activity
OZN62_03320	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OZN62_03335	COG0028	Belongs to the TPP enzyme family
OZN62_03345	COG5001	Diguanylate cyclase
OZN62_03345	COG3300	MHYT domain
OZN62_03350	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OZN62_03355	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OZN62_03360	COG0552	protein localization to endoplasmic reticulum
OZN62_03365	COG2917	probably involved in intracellular septation
OZN62_03380	COG3158	transport of potassium into the cell
OZN62_03395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OZN62_03400	COG1138	Cytochrome C-type biogenesis protein
OZN62_03405	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
OZN62_03415	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OZN62_03445	COG0254	rRNA binding
OZN62_03450	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OZN62_03465	COG0750	zinc metalloprotease
OZN62_03470	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
OZN62_03480	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OZN62_03485	COG0233	cytoplasmic translational termination
OZN62_03490	COG0528	UMP kinase activity
OZN62_03495	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OZN62_03500	COG0052	Belongs to the universal ribosomal protein uS2 family
OZN62_03515	COG0688	phosphatidylethanolamine metabolic process
OZN62_03550	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OZN62_03560	COG0776	regulation of translation
OZN62_03585	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OZN62_03600	COG1643	Atp-dependent helicase
OZN62_03605	COG0142	geranyltranstransferase activity
OZN62_03610	COG1605	Chorismate mutase
OZN62_03610	COG0287	Prephenate dehydrogenase
OZN62_03655	COG0438	transferase activity, transferring glycosyl groups
OZN62_03660	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OZN62_03665	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OZN62_03670	COG1862	Preprotein translocase
OZN62_03690	COG2319	Wd-40 repeat
OZN62_03735	COG4770	biotin carboxylase activity
OZN62_03740	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OZN62_03740	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OZN62_03745	COG2353	YceI-like domain
OZN62_03755	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
OZN62_03760	COG0511	ligase activity, forming carbon-carbon bonds
OZN62_03765	COG0439	Biotin carboxylase
OZN62_03780	COG1522	sequence-specific DNA binding
OZN62_03785	COG2205	protein histidine kinase activity
OZN62_03800	COG1525	nuclease
OZN62_03820	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
OZN62_03830	COG0488	(ABC) transporter
OZN62_03840	COG3920	Histidine kinase
OZN62_03840	COG2202	Pas domain
OZN62_03845	COG2020	methyltransferase activity
OZN62_03865	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
OZN62_03870	COG0668	transmembrane transport
OZN62_03895	COG1199	ATP-dependent helicase activity
OZN62_03895	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OZN62_03910	COG0776	regulation of translation
OZN62_03915	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OZN62_03920	COG0416	fatty acid biosynthetic process
OZN62_03925	COG0333	Belongs to the bacterial ribosomal protein bL32 family
OZN62_03930	COG3788	relative of glutathione S-transferase, MAPEG superfamily
OZN62_03935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OZN62_03940	COG0456	acetyltransferase
OZN62_03980	COG0215	cysteine-tRNA ligase activity
OZN62_04020	COG3046	protein related to deoxyribodipyrimidine photolyase
OZN62_04035	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OZN62_04035	COG2169	Transcriptional regulator
OZN62_04045	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OZN62_04050	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OZN62_04055	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OZN62_04065	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OZN62_04070	COG0355	proton-transporting ATP synthase activity, rotational mechanism
OZN62_04110	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OZN62_04140	COG0697	spore germination
OZN62_04160	COG0385	Bile acid
OZN62_04170	COG0232	Belongs to the dGTPase family. Type 2 subfamily
OZN62_04180	COG1404	Belongs to the peptidase S8 family
OZN62_04215	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OZN62_04220	COG2189	Belongs to the N(4) N(6)-methyltransferase family
OZN62_04230	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OZN62_04235	COG2133	pyrroloquinoline quinone binding
OZN62_04255	COG0617	tRNA 3'-terminal CCA addition
OZN62_04265	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OZN62_04270	COG0693	protein deglycase activity
OZN62_04290	COG1104	cysteine desulfurase activity
OZN62_04295	COG1104	cysteine desulfurase activity
OZN62_04300	COG2945	thiolester hydrolase activity
OZN62_04325	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OZN62_04340	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
OZN62_04345	COG0745	RESPONSE REGULATOR receiver
OZN62_04350	COG2205	protein histidine kinase activity
OZN62_04360	COG1660	Displays ATPase and GTPase activities
OZN62_04365	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OZN62_04365	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
OZN62_04370	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OZN62_04375	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OZN62_04385	COG1322	Protein conserved in bacteria
OZN62_04390	COG2759	Belongs to the formate--tetrahydrofolate ligase family
OZN62_04395	COG0242	peptide deformylase activity
OZN62_04400	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OZN62_04405	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OZN62_04410	COG0101	tRNA pseudouridine synthase activity
OZN62_04420	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OZN62_04445	COG5507	3-demethylubiquinone-9 3-methyltransferase
OZN62_04450	COG0625	glutathione transferase activity
OZN62_04470	COG1741	Belongs to the pirin family
OZN62_04480	COG0596	Alpha beta hydrolase
OZN62_04490	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OZN62_04495	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OZN62_04500	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OZN62_04505	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OZN62_04510	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
OZN62_04535	COG0322	excinuclease ABC activity
OZN62_04540	COG0531	amino acid
OZN62_04555	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OZN62_04560	COG0424	maF-like protein
OZN62_04610	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
OZN62_04615	COG0612	Peptidase, M16
OZN62_04620	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OZN62_04625	COG0047	phosphoribosylformylglycinamidine synthase activity
OZN62_04630	COG5001	Diguanylate cyclase
OZN62_04635	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OZN62_04650	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OZN62_04655	COG0546	phosphoglycolate phosphatase activity
OZN62_04670	COG1045	serine acetyltransferase
OZN62_04685	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
OZN62_04690	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OZN62_04705	COG0105	UTP biosynthetic process
OZN62_04725	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OZN62_04735	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OZN62_04740	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
OZN62_04745	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OZN62_04765	COG3724	N-succinylarginine dihydrolase activity
OZN62_04780	COG1970	mechanosensitive ion channel activity
OZN62_04805	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OZN62_04820	COG0572	uridine kinase
OZN62_04830	COG4993	Dehydrogenase
OZN62_04890	COG4993	Dehydrogenase
OZN62_04890	COG2010	Cytochrome c
OZN62_04905	COG4993	Dehydrogenase
OZN62_04920	COG2382	esterase
OZN62_04920	COG3507	Belongs to the glycosyl hydrolase 43 family
OZN62_04920	COG3693	PFAM glycoside hydrolase, family 10
OZN62_04925	COG4566	intracellular signal transduction
OZN62_04930	COG1132	(ABC) transporter
OZN62_04950	COG4638	Rieske (2fe-2S)
OZN62_04965	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
OZN62_04975	COG2116	formate transmembrane transporter activity
OZN62_04985	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
OZN62_05000	COG2989	Protein conserved in bacteria
OZN62_05020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OZN62_05030	COG1960	acyl-CoA dehydrogenase activity
OZN62_05045	COG1216	Glycosyl transferase, family 2
OZN62_05055	COG1442	glycosyl transferase family 8
OZN62_05055	COG1216	Glycosyl transferase, family 2
OZN62_05080	COG0438	transferase activity, transferring glycosyl groups
OZN62_05110	COG3386	PFAM SMP-30 Gluconolaconase
OZN62_05130	COG0183	Belongs to the thiolase family
OZN62_05145	COG0842	Transport permease protein
OZN62_05155	COG0477	Major facilitator Superfamily
OZN62_05170	COG4106	trans-aconitate 2-methyltransferase activity
OZN62_05175	COG1185	polyribonucleotide nucleotidyltransferase activity
OZN62_05180	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OZN62_05185	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OZN62_05190	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
OZN62_05200	COG1435	thymidine kinase activity
OZN62_05205	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OZN62_05215	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OZN62_05230	COG0779	Required for maturation of 30S ribosomal subunits
OZN62_05240	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
OZN62_05270	COG1842	Phage shock protein A
OZN62_05315	COG2166	iron-sulfur cluster assembly
OZN62_05340	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OZN62_05355	COG0066	3-isopropylmalate dehydratase activity
OZN62_05370	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
OZN62_05380	COG2135	peptidase activity
OZN62_05410	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OZN62_05420	COG4181	ATPase activity
OZN62_05430	COG1714	RDD family
OZN62_05435	COG4771	TonB-dependent receptor
OZN62_05440	COG1217	gtp-binding protein TYPA
OZN62_05450	COG0438	transferase activity, transferring glycosyl groups
OZN62_05465	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OZN62_05485	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OZN62_05490	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OZN62_05495	COG2897	thiosulfate sulfurtransferase activity
OZN62_05505	COG0668	transmembrane transport
OZN62_05515	COG1648	precorrin-2 dehydrogenase activity
OZN62_05515	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OZN62_05535	COG0175	sulfate reduction
OZN62_05550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OZN62_05555	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OZN62_05560	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OZN62_05575	COG0670	Belongs to the BI1 family
OZN62_05580	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OZN62_05600	COG0849	cell division
OZN62_05605	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OZN62_05610	COG1181	Belongs to the D-alanine--D-alanine ligase family
OZN62_05615	COG0812	UDP-N-acetylmuramate dehydrogenase activity
OZN62_05620	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OZN62_05625	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OZN62_05635	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OZN62_05640	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OZN62_05645	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OZN62_05650	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OZN62_05665	COG0275	rRNA processing
OZN62_05670	COG2001	Belongs to the MraZ family
OZN62_05685	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OZN62_05725	COG2154	pterin-4-alpha-carbinolamine dehydratase
OZN62_05730	COG4133	protoheme IX ABC transporter activity
OZN62_05735	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OZN62_05755	COG0024	Methionine aminopeptidase
OZN62_05765	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OZN62_05785	COG0174	glutamine synthetase
OZN62_05795	COG1476	TRANSCRIPTIONal
OZN62_05810	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
OZN62_05820	COG0729	surface antigen
OZN62_05825	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
OZN62_05830	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OZN62_05835	COG2084	Dehydrogenase
OZN62_05840	COG1574	metal-dependent hydrolase with the TIM-barrel fold
OZN62_05850	COG0805	protein transport
OZN62_05855	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OZN62_05860	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OZN62_05865	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OZN62_05870	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OZN62_05885	COG0018	arginyl-trna synthetase
OZN62_05895	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OZN62_05900	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OZN62_05905	COG0328	RNA-DNA hybrid ribonuclease activity
OZN62_05910	COG3422	double-strand break repair
OZN62_05915	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OZN62_05915	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
OZN62_05935	COG4964	Belongs to the GSP D family
OZN62_05965	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
OZN62_06005	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OZN62_06015	COG0154	amidase activity
OZN62_06020	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OZN62_06030	COG0828	Belongs to the bacterial ribosomal protein bS21 family
OZN62_06035	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OZN62_06080	COG0525	valine-tRNA ligase activity
OZN62_06105	COG0730	response to heat
OZN62_06115	COG1215	transferase activity, transferring glycosyl groups
OZN62_06120	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OZN62_06135	COG0544	peptidyl-prolyl cis-trans isomerase activity
OZN62_06145	COG0154	amidase activity
OZN62_06155	COG0740	serine-type endopeptidase activity
OZN62_06160	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OZN62_06180	COG1230	cation diffusion facilitator family transporter
OZN62_06195	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OZN62_06200	COG0564	pseudouridine synthase activity
OZN62_06215	COG3023	N-Acetylmuramoyl-L-alanine amidase
OZN62_06225	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OZN62_06240	COG0346	lactoylglutathione lyase activity
OZN62_06245	COG1160	GTP binding
OZN62_06265	COG2311	Membrane
OZN62_06290	COG1028	Short-chain dehydrogenase reductase Sdr
OZN62_06295	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OZN62_06300	COG0540	Belongs to the ATCase OTCase family
OZN62_06305	COG0616	signal peptide processing
OZN62_06315	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OZN62_06325	COG0745	RESPONSE REGULATOR receiver
OZN62_06345	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OZN62_06350	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
OZN62_06365	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OZN62_06380	COG0432	Pfam Uncharacterised protein family UPF0047
OZN62_06390	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OZN62_06395	COG0129	dihydroxy-acid dehydratase activity
OZN62_06400	COG0837	glucose binding
OZN62_06405	COG0800	Aldolase
OZN62_06420	COG0037	tRNA processing
OZN62_06430	COG1426	Protein conserved in bacteria
OZN62_06435	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
OZN62_06455	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OZN62_06460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OZN62_06475	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OZN62_06495	COG1902	pentaerythritol trinitrate reductase activity
OZN62_06510	COG0321	lipoyl(octanoyl) transferase activity
OZN62_06520	COG1393	Belongs to the ArsC family
OZN62_06530	COG2080	2 iron, 2 sulfur cluster binding
OZN62_06540	COG0235	Class ii aldolase
OZN62_06555	COG2271	Major facilitator Superfamily
OZN62_06565	COG2072	flavoprotein involved in K transport
OZN62_06585	COG1028	Short-chain dehydrogenase reductase Sdr
OZN62_06600	COG1063	alcohol dehydrogenase
OZN62_06610	COG0784	Response regulator, receiver
OZN62_06645	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
OZN62_06655	COG3243	poly(R)-hydroxyalkanoic acid synthase
OZN62_06660	COG0436	Aminotransferase
OZN62_06665	COG0745	RESPONSE REGULATOR receiver
OZN62_06675	COG0129	dihydroxy-acid dehydratase activity
OZN62_06685	COG0445	tRNA wobble uridine modification
OZN62_06700	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OZN62_06790	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
OZN62_06805	COG5001	Diguanylate cyclase
OZN62_06820	COG0514	ATP-dependent DNA helicase (RecQ)
OZN62_06845	COG2311	Membrane
OZN62_06860	COG1475	DNA binding
OZN62_06875	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
OZN62_06880	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OZN62_06900	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
OZN62_06905	COG4149	molybdate abc transporter
OZN62_06910	COG0725	ABC transporter, periplasmic molybdate-binding protein
OZN62_06915	COG3920	Histidine kinase
OZN62_06945	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OZN62_06955	COG0351	phosphomethylpyrimidine kinase
OZN62_06955	COG0352	thiamine-phosphate diphosphorylase activity
OZN62_06955	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OZN62_06960	COG1611	Belongs to the LOG family
OZN62_07000	COG0450	alkyl hydroperoxide reductase
OZN62_07005	COG0640	Transcriptional regulator
OZN62_07010	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OZN62_07015	COG0156	8-amino-7-oxononanoate synthase activity
OZN62_07020	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
OZN62_07025	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OZN62_07090	COG4964	Belongs to the GSP D family
OZN62_07110	COG4566	intracellular signal transduction
OZN62_07115	COG4191	Histidine kinase
OZN62_07130	COG2226	methyltransferase
OZN62_07160	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
OZN62_07195	COG0714	Associated with various cellular activities
OZN62_07215	COG0668	transmembrane transport
OZN62_07220	COG0456	acetyltransferase
OZN62_07225	COG2200	EAL domain
OZN62_07225	COG2199	diguanylate cyclase activity
OZN62_07240	COG2223	nitrite transmembrane transporter activity
OZN62_07245	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OZN62_07280	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OZN62_07285	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OZN62_07305	COG2255	four-way junction helicase activity
OZN62_07320	COG0632	four-way junction helicase activity
OZN62_07325	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OZN62_07330	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
OZN62_07340	COG0450	alkyl hydroperoxide reductase
OZN62_07345	COG3634	alkyl hydroperoxide reductase activity
OZN62_07350	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
OZN62_07365	COG4395	Tim44
OZN62_07370	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
OZN62_07375	COG0728	peptidoglycan biosynthetic process
OZN62_07380	COG0180	Tryptophanyl-tRNA synthetase
OZN62_07395	COG0756	dUTP diphosphatase activity
OZN62_07400	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OZN62_07410	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OZN62_07415	COG2226	methyltransferase
OZN62_07420	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OZN62_07425	COG0268	Binds directly to 16S ribosomal RNA
OZN62_07430	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OZN62_07435	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OZN62_07450	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OZN62_07455	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
OZN62_07460	COG0501	Belongs to the peptidase M48B family
OZN62_07475	COG1301	dicarboxylic acid transport
OZN62_07480	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OZN62_07490	COG0625	glutathione transferase activity
OZN62_07495	COG5001	Diguanylate cyclase
OZN62_07500	COG0218	Necessary for normal cell division and for the maintenance of normal septation
OZN62_07505	COG0706	membrane insertase activity
OZN62_07510	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
OZN62_07515	COG0594	ribonuclease P activity
OZN62_07520	COG0230	Belongs to the bacterial ribosomal protein bL34 family
OZN62_07555	COG0257	Belongs to the bacterial ribosomal protein bL36 family
OZN62_07570	COG2866	Carboxypeptidase
OZN62_07585	COG5328	Belongs to the UPF0262 family
OZN62_07590	COG0305	Participates in initiation and elongation during chromosome replication
OZN62_07600	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OZN62_07605	COG1758	RNA polymerase activity
OZN62_07655	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OZN62_07660	COG0730	response to heat
OZN62_07665	COG1482	cell wall glycoprotein biosynthetic process
OZN62_07670	COG1024	Enoyl-CoA hydratase
OZN62_07715	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OZN62_07730	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
OZN62_07775	COG1585	Membrane protein implicated in regulation of membrane protease activity
OZN62_07780	COG0330	HflC and HflK could
OZN62_07795	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OZN62_07805	COG0318	PFAM AMP-dependent synthetase and ligase
OZN62_07810	COG3618	amidohydrolase
OZN62_07820	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OZN62_07830	COG2159	amidohydrolase
OZN62_07860	COG0667	Aldo Keto reductase
OZN62_07910	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OZN62_07920	COG1012	belongs to the aldehyde dehydrogenase family
OZN62_07945	COG2175	clavaminate synthase activity
OZN62_07970	COG0404	The glycine cleavage system catalyzes the degradation of glycine
OZN62_07980	COG3964	amidohydrolase
OZN62_07995	COG0527	aspartate kinase activity
OZN62_08000	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OZN62_08005	COG0584	glycerophosphoryl diester phosphodiesterase
OZN62_08010	COG1393	Belongs to the ArsC family
OZN62_08020	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
OZN62_08025	COG0217	transcriptional regulatory protein
OZN62_08030	COG3750	Belongs to the UPF0335 family
OZN62_08040	COG0469	pyruvate kinase activity
OZN62_08060	COG2095	MarC family integral membrane protein
OZN62_08075	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
OZN62_08105	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OZN62_08120	COG1372	Participates in initiation and elongation during chromosome replication
OZN62_08120	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OZN62_08140	COG2162	N-hydroxyarylamine O-acetyltransferase activity
OZN62_08155	COG4589	Belongs to the CDS family
OZN62_08175	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OZN62_08175	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OZN62_08200	COG1131	(ABC) transporter
OZN62_08235	COG0519	Catalyzes the synthesis of GMP from XMP
OZN62_08235	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OZN62_08250	COG0628	permease
OZN62_08275	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OZN62_08285	COG2382	esterase
OZN62_08290	COG1960	acyl-CoA dehydrogenase activity
OZN62_08295	COG3920	Histidine kinase
OZN62_08300	COG1125	glycine betaine transport
OZN62_08300	COG0517	IMP dehydrogenase activity
OZN62_08305	COG1174	glycine betaine transport
OZN62_08315	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OZN62_08320	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
OZN62_08325	COG5001	Diguanylate cyclase
OZN62_08325	COG3447	MASE1 domain protein
OZN62_08325	COG5002	protein histidine kinase activity
OZN62_08325	COG5001	Diguanylate cyclase
OZN62_08325	COG5002	protein histidine kinase activity
OZN62_08325	COG3447	MASE1 domain protein
OZN62_08335	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OZN62_08340	COG0352	thiamine-phosphate diphosphorylase activity
OZN62_08345	COG1674	ftsk spoiiie
OZN62_08350	COG0189	ligase activity
OZN62_08350	COG4067	protein conserved in archaea
OZN62_08355	COG0189	ligase activity
OZN62_08370	COG0189	ligase activity
OZN62_08430	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OZN62_08435	COG0686	Belongs to the AlaDH PNT family
OZN62_08440	COG3706	GGDEF domain
OZN62_08470	COG2205	protein histidine kinase activity
OZN62_08475	COG0433	COG0433 Predicted ATPase
OZN62_08480	COG0512	Glutamine amidotransferase of anthranilate synthase
OZN62_08480	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OZN62_08490	COG0564	pseudouridine synthase activity
OZN62_08500	COG0267	Belongs to the bacterial ribosomal protein bL33 family
OZN62_08515	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OZN62_08515	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OZN62_08530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OZN62_08545	COG0514	ATP-dependent DNA helicase (RecQ)
OZN62_08560	COG3186	Phenylalanine-4-hydroxylase
OZN62_08575	COG1968	undecaprenyl-diphosphatase activity
OZN62_08580	COG3590	peptidase
OZN62_08585	COG1132	(ABC) transporter
OZN62_08620	COG0070	glutamate synthase
OZN62_08620	COG0067	glutamate synthase
OZN62_08620	COG0069	glutamate synthase activity
OZN62_08660	COG2755	lipolytic protein G-D-S-L family
OZN62_08660	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
OZN62_08670	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OZN62_08675	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
OZN62_08715	COG0367	asparagine synthase
OZN62_08740	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
OZN62_08745	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
OZN62_08770	COG0110	maltose O-acetyltransferase activity
OZN62_08805	COG0489	protein tyrosine kinase activity
OZN62_08805	COG3206	protein involved in exopolysaccharide biosynthesis
OZN62_08820	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
OZN62_08825	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OZN62_08845	COG0495	leucyl-tRNA aminoacylation
OZN62_08860	COG1028	Short-chain dehydrogenase reductase Sdr
OZN62_08875	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OZN62_08880	COG0739	heme binding
OZN62_08885	COG2833	Protein of unknown function (DUF455)
OZN62_08890	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OZN62_08895	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
OZN62_08915	COG0175	sulfate reduction
OZN62_08925	COG1218	3'(2'),5'-bisphosphate nucleotidase
OZN62_08945	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OZN62_08955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OZN62_08960	COG2902	Dehydrogenase
OZN62_08970	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OZN62_08975	COG4152	abc transporter atp-binding protein
OZN62_09000	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OZN62_09000	COG0493	'glutamate synthase
OZN62_09055	COG1028	Short-chain dehydrogenase reductase Sdr
OZN62_09070	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OZN62_09075	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OZN62_09090	COG4771	TonB-dependent receptor
OZN62_09100	COG2188	Transcriptional regulator
OZN62_09105	COG3104	oligopeptide transport
OZN62_09110	COG1228	amidohydrolase
OZN62_09120	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OZN62_09130	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OZN62_09135	COG0138	bifunctional purine biosynthesis protein purh
OZN62_09165	COG1473	amidohydrolase
OZN62_09275	COG3275	phosphorelay sensor kinase activity
OZN62_09280	COG3279	Response regulator of the LytR AlgR family
OZN62_09300	COG0071	Belongs to the small heat shock protein (HSP20) family
OZN62_09305	COG0590	tRNA wobble adenosine to inosine editing
OZN62_09310	COG0227	Belongs to the bacterial ribosomal protein bL28 family
OZN62_09330	COG1570	exodeoxyribonuclease VII activity
OZN62_09335	COG0151	Belongs to the GarS family
OZN62_09340	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OZN62_09345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OZN62_09365	COG0316	Belongs to the HesB IscA family
OZN62_09375	COG2151	metal-sulfur cluster biosynthetic enzyme
OZN62_09380	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OZN62_09390	COG0719	Fe-S assembly protein
OZN62_09395	COG0396	ATPase activity
OZN62_09405	COG0719	Fe-S assembly protein
OZN62_09435	COG0167	dihydroorotate dehydrogenase activity
OZN62_09440	COG0405	Gamma-glutamyltransferase
OZN62_09445	COG1022	Amp-dependent synthetase and ligase
OZN62_09455	COG2022	thiamine diphosphate biosynthetic process
OZN62_09470	COG1612	heme a metabolic process
OZN62_09485	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OZN62_09490	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OZN62_09495	COG0784	Response regulator, receiver
OZN62_09500	COG1446	asparaginase
OZN62_09525	COG3275	phosphorelay sensor kinase activity
OZN62_09535	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OZN62_09565	COG0316	Belongs to the HesB IscA family
OZN62_09575	COG3773	Cell wall hydrolase
OZN62_09575	COG3409	Peptidoglycan-binding domain 1 protein
OZN62_09590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OZN62_09595	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
OZN62_09600	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OZN62_09605	COG0237	dephospho-CoA kinase activity
OZN62_09610	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OZN62_09615	COG0424	maF-like protein
OZN62_09620	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
OZN62_09625	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OZN62_09635	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
OZN62_09655	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OZN62_09660	COG0445	tRNA wobble uridine modification
OZN62_09665	COG0357	Ribosomal RNA small subunit methyltransferase G
OZN62_09685	COG1956	GAF domain-containing protein
OZN62_09700	COG0009	L-threonylcarbamoyladenylate synthase
OZN62_09715	COG1329	Transcriptional regulator
OZN62_09725	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
OZN62_09730	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OZN62_09740	COG0739	heme binding
OZN62_09745	COG0113	porphobilinogen synthase activity
OZN62_09750	COG0519	Catalyzes the synthesis of GMP from XMP
OZN62_09760	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OZN62_09765	COG1872	DUF167
OZN62_09770	COG1793	dna ligase
OZN62_09775	COG1793	dna ligase
OZN62_09775	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
OZN62_09810	COG0438	transferase activity, transferring glycosyl groups
OZN62_09825	COG0739	heme binding
OZN62_09830	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OZN62_09835	COG0667	Aldo Keto reductase
OZN62_09840	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OZN62_09845	COG0799	negative regulation of ribosome biogenesis
OZN62_09850	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OZN62_09860	COG0793	Belongs to the peptidase S41A family
OZN62_09870	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
OZN62_09885	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
OZN62_09890	COG1295	ribonuclease BN
OZN62_09895	COG0484	heat shock protein binding
OZN62_09900	COG0259	pyridoxamine-phosphate oxidase activity
OZN62_09905	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OZN62_09925	COG0482	sulfurtransferase activity
OZN62_09945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OZN62_09955	COG2733	membrane
OZN62_09970	COG2086	electron transfer activity
OZN62_09985	COG0045	succinate-CoA ligase (ADP-forming) activity
OZN62_09990	COG0483	inositol monophosphate 1-phosphatase activity
OZN62_09995	COG2885	chlorophyll binding
OZN62_10000	COG1253	flavin adenine dinucleotide binding
OZN62_10010	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OZN62_10015	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OZN62_10020	COG0196	riboflavin kinase activity
OZN62_10035	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OZN62_10045	COG0588	phosphoglycerate mutase activity
OZN62_10095	COG0308	aminopeptidase N
OZN62_10100	COG1496	oxidoreductase activity
OZN62_10115	COG2857	Cytochrome c1
OZN62_10115	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
OZN62_10120	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OZN62_10140	COG3119	arylsulfatase activity
OZN62_10155	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OZN62_10160	COG1192	Involved in chromosome partitioning
OZN62_10180	COG1201	RNA secondary structure unwinding
OZN62_10225	COG1494	fructose-1,6-bisphosphatase
OZN62_10240	COG0662	Cupin 2, conserved barrel domain protein
OZN62_10245	COG0483	inositol monophosphate 1-phosphatase activity
OZN62_10255	COG0291	Belongs to the bacterial ribosomal protein bL35 family
OZN62_10260	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OZN62_10265	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OZN62_10270	COG0072	phenylalanine-tRNA ligase activity
OZN62_10275	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OZN62_10290	COG0347	Belongs to the P(II) protein family
OZN62_10295	COG0004	ammonium transporteR
OZN62_10300	COG0347	Belongs to the P(II) protein family
OZN62_10325	COG1278	Cold shock
OZN62_10330	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OZN62_10335	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OZN62_10350	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OZN62_10360	COG2032	superoxide dismutase activity
OZN62_10380	COG0798	PFAM Bile acid sodium symporter
OZN62_10385	COG0156	8-amino-7-oxononanoate synthase activity
OZN62_10455	COG3483	tryptophan 2,3-dioxygenase activity
OZN62_10470	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OZN62_10490	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OZN62_10495	COG0280	phosphate acetyltransferase
OZN62_10495	COG0281	malic enzyme
OZN62_10510	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OZN62_10515	COG0745	RESPONSE REGULATOR receiver
OZN62_10520	COG4716	Myosin-crossreactive antigen
OZN62_10525	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
OZN62_10530	COG1137	ATPase activity
OZN62_10540	COG0668	transmembrane transport
OZN62_10550	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
OZN62_10555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OZN62_10560	COG0124	histidyl-tRNA synthetase
OZN62_10565	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OZN62_10570	COG2890	protein-(glutamine-N5) methyltransferase activity
OZN62_10580	COG0815	Transfers the fatty acyl group on membrane lipoproteins
OZN62_10585	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OZN62_10590	COG2311	Membrane
OZN62_10595	COG2814	Major facilitator Superfamily
OZN62_10635	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OZN62_10645	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OZN62_10645	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OZN62_10670	COG3667	copper resistance
OZN62_10675	COG2132	Multicopper oxidase
OZN62_10680	COG1937	Protein conserved in bacteria
OZN62_10695	COG0459	protein refolding
OZN62_10700	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OZN62_10705	COG0534	Mate efflux family protein
OZN62_10720	COG0222	ribosome binding
OZN62_10725	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OZN62_10730	COG3655	Transcriptional regulator
OZN62_10750	COG0085	RNA polymerase activity
OZN62_10755	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OZN62_10770	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OZN62_10770	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
OZN62_10775	COG4771	TonB-dependent receptor
OZN62_10790	COG0717	Belongs to the dCTP deaminase family
OZN62_10815	COG0204	Acyl-transferase
OZN62_10830	COG2884	Cell division ATP-binding protein ftsE
OZN62_10845	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
OZN62_10845	COG2885	chlorophyll binding
OZN62_10865	COG0287	Prephenate dehydrogenase
OZN62_10870	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OZN62_10875	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OZN62_10880	COG2813	Specifically methylates the guanine in position
OZN62_10880	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OZN62_10890	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OZN62_10900	COG3383	formate dehydrogenase (NAD+) activity
OZN62_10905	COG0746	molybdenum cofactor guanylyltransferase activity
OZN62_10920	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
OZN62_10940	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
OZN62_10980	COG2814	Major facilitator Superfamily
OZN62_11025	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OZN62_11030	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OZN62_11045	COG0330	HflC and HflK could
OZN62_11050	COG0489	protein tyrosine kinase activity
OZN62_11060	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
OZN62_11080	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OZN62_11100	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OZN62_11100	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OZN62_11105	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OZN62_11115	COG0643	Histidine kinase
OZN62_11115	COG2198	Histidine kinase
OZN62_11125	COG0745	RESPONSE REGULATOR receiver
OZN62_11135	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
OZN62_11140	COG3300	MHYT domain
OZN62_11140	COG5001	Diguanylate cyclase
OZN62_11175	COG3119	arylsulfatase activity
OZN62_11230	COG0318	PFAM AMP-dependent synthetase and ligase
OZN62_11250	COG4765	Protein conserved in bacteria
OZN62_11255	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
OZN62_11270	COG1115	amino acid carrier protein
OZN62_11285	COG0583	DNA-binding transcription factor activity
OZN62_11290	COG0473	3-isopropylmalate dehydrogenase activity
OZN62_11300	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OZN62_11305	COG0081	regulation of translation
OZN62_11310	COG2755	lipolytic protein G-D-S-L family
OZN62_11310	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
OZN62_11315	COG1546	Belongs to the CinA family
OZN62_11315	COG1058	Belongs to the CinA family
OZN62_11325	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OZN62_11335	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
OZN62_11345	COG0404	The glycine cleavage system catalyzes the degradation of glycine
OZN62_11355	COG1414	Transcriptional regulator
OZN62_11375	COG1028	Short-chain dehydrogenase reductase Sdr
OZN62_11415	COG1846	Transcriptional regulator
OZN62_11450	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
OZN62_11455	COG0702	epimerase
OZN62_11485	COG1012	belongs to the aldehyde dehydrogenase family
OZN62_11495	COG0657	acetylesterase activity
OZN62_11500	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OZN62_11515	COG0248	Ppx GppA phosphatase
OZN62_11520	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
OZN62_11525	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
OZN62_11540	COG3704	protein secretion by the type IV secretion system
OZN62_11545	COG3451	type IV secretory pathway VirB4
OZN62_11560	COG0739	heme binding
OZN62_11560	COG0741	lytic transglycosylase activity
OZN62_11560	COG1196	nuclear chromosome segregation
OZN62_11595	COG1609	Transcriptional regulator
OZN62_11605	COG1472	Belongs to the glycosyl hydrolase 3 family
OZN62_11620	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OZN62_11625	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OZN62_11635	COG0404	The glycine cleavage system catalyzes the degradation of glycine
OZN62_11655	COG0297	glycogen (starch) synthase activity
OZN62_11695	COG1216	Glycosyl transferase, family 2
OZN62_11730	COG1448	Aminotransferase
OZN62_11745	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OZN62_11745	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OZN62_11760	COG2983	Belongs to the UPF0260 family
OZN62_11765	COG1999	signal sequence binding
OZN62_11770	COG0666	response to abiotic stimulus
OZN62_11790	COG0629	single-stranded DNA binding
OZN62_11810	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
OZN62_11815	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
OZN62_11820	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OZN62_11830	COG1823	symporter activity
OZN62_11835	COG0659	secondary active sulfate transmembrane transporter activity
OZN62_11845	COG5265	(ABC) transporter
OZN62_11860	COG1216	Glycosyl transferase, family 2
OZN62_11935	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OZN62_11945	COG1024	Enoyl-CoA hydratase
OZN62_11960	COG0251	oxidation-reduction process
OZN62_11985	COG2376	Dihydroxyacetone kinase
OZN62_11995	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OZN62_12015	COG0783	Belongs to the Dps family
OZN62_12025	COG0494	nUDIX hydrolase
OZN62_12035	COG2814	Major facilitator Superfamily
OZN62_12080	COG4946	Tricorn protease homolog
OZN62_12080	COG1506	peptidase
OZN62_12080	COG0823	Involved in the tonB-independent uptake of proteins
OZN62_12095	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
OZN62_12105	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
OZN62_12120	COG1278	Cold shock
OZN62_12160	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
OZN62_12200	COG3384	dioxygenase
OZN62_12210	COG0457	Tetratricopeptide repeat
OZN62_12240	COG2171	N-acyltransferase activity
OZN62_12250	COG0194	GDP metabolic process
OZN62_12265	COG0131	Imidazoleglycerol-phosphate dehydratase
OZN62_12270	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OZN62_12275	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OZN62_12280	COG0107	imidazoleglycerol-phosphate synthase activity
OZN62_12290	COG0140	phosphoribosyl-ATP diphosphatase activity
OZN62_12300	COG0824	Thioesterase
OZN62_12305	COG0811	peptide transport
OZN62_12320	COG0823	Involved in the tonB-independent uptake of proteins
OZN62_12325	COG2885	chlorophyll binding
OZN62_12335	COG0484	heat shock protein binding
OZN62_12365	COG0471	metal ion transport
OZN62_12380	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OZN62_12390	COG0408	coproporphyrinogen oxidase activity
OZN62_12435	COG3268	Saccharopine dehydrogenase
OZN62_12450	COG0641	radical SAM
OZN62_12470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OZN62_12495	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OZN62_12520	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OZN62_12540	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OZN62_12555	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OZN62_12570	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OZN62_12575	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OZN62_12585	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
OZN62_12610	COG0577	efflux transmembrane transporter activity
OZN62_12610	COG1136	(ABC) transporter
OZN62_12615	COG1136	(ABC) transporter
OZN62_12615	COG0577	efflux transmembrane transporter activity
OZN62_12620	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OZN62_12645	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OZN62_12655	COG0346	lactoylglutathione lyase activity
OZN62_12670	COG0511	ligase activity, forming carbon-carbon bonds
OZN62_12680	COG0574	Belongs to the PEP-utilizing enzyme family
OZN62_12680	COG3848	Pyruvate phosphate dikinase
OZN62_12720	COG1012	belongs to the aldehyde dehydrogenase family
OZN62_12750	COG1024	Enoyl-CoA hydratase
OZN62_12765	COG2885	chlorophyll binding
OZN62_12765	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
OZN62_12770	COG1960	acyl-CoA dehydrogenase activity
OZN62_12780	COG0261	This protein binds to 23S rRNA in the presence of protein L20
OZN62_12780	COG3743	rRNA binding
OZN62_12790	COG2304	oxidoreductase activity
OZN62_12800	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
OZN62_12805	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OZN62_12810	COG0181	hydroxymethylbilane synthase activity
OZN62_12825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OZN62_12845	COG0556	nucleotide-excision repair
OZN62_12875	COG2308	Evidence 4 Homologs of previously reported genes of
OZN62_12905	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
OZN62_12910	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OZN62_12915	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
OZN62_12920	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OZN62_12930	COG0252	asparaginase activity
OZN62_12940	COG3118	belongs to the thioredoxin family
OZN62_12945	COG0165	Argininosuccinate lyase
OZN62_12955	COG0019	diaminopimelate decarboxylase activity
OZN62_12960	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OZN62_12960	COG1648	precorrin-2 dehydrogenase activity
OZN62_12980	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OZN62_13000	COG0736	holo-[acyl-carrier-protein] synthase activity
OZN62_13005	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
OZN62_13010	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OZN62_13015	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OZN62_13020	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OZN62_13025	COG0109	protoheme IX farnesyltransferase activity
OZN62_13035	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
OZN62_13080	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OZN62_13090	COG0314	molybdopterin synthase activity
OZN62_13100	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OZN62_13110	COG0261	This protein binds to 23S rRNA in the presence of protein L20
OZN62_13115	COG0211	Belongs to the bacterial ribosomal protein bL27 family
OZN62_13140	COG0418	dihydroorotase activity
OZN62_13150	COG1012	belongs to the aldehyde dehydrogenase family
OZN62_13160	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
OZN62_13170	COG0297	glycogen (starch) synthase activity
OZN62_13190	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
OZN62_13195	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OZN62_13210	COG0789	Transcriptional regulator
OZN62_13215	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OZN62_13230	COG1196	nuclear chromosome segregation
OZN62_13240	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OZN62_13240	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OZN62_13265	COG2816	NAD+ diphosphatase activity
OZN62_13300	COG2239	Acts as a magnesium transporter
OZN62_13315	COG0583	DNA-binding transcription factor activity
OZN62_13320	COG1253	flavin adenine dinucleotide binding
OZN62_13325	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OZN62_13340	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OZN62_13355	COG4957	zinc ion binding
OZN62_13370	COG0778	Nitroreductase
OZN62_13375	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
OZN62_13380	COG0612	Peptidase, M16
OZN62_13385	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
OZN62_13400	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OZN62_13405	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
OZN62_13415	COG2271	Major facilitator Superfamily
OZN62_13420	COG3119	arylsulfatase activity
OZN62_13445	COG0625	glutathione transferase activity
OZN62_13465	COG1054	Belongs to the UPF0176 family
OZN62_13480	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OZN62_13515	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
OZN62_13520	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
OZN62_13540	COG1381	Involved in DNA repair and RecF pathway recombination
OZN62_13545	COG0473	3-isopropylmalate dehydrogenase activity
OZN62_13560	COG1928	C-terminal four TMM region of protein-O-mannosyltransferase
OZN62_13570	COG2967	ApaG domain
OZN62_13580	COG0583	DNA-binding transcription factor activity
OZN62_13650	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OZN62_13655	COG0049	tRNA binding
OZN62_13660	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OZN62_13665	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OZN62_13670	COG0051	transcription antitermination factor activity, RNA binding
OZN62_13675	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OZN62_13680	COG0088	Forms part of the polypeptide exit tunnel
OZN62_13685	COG0089	rRNA binding
OZN62_13690	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OZN62_13695	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OZN62_13700	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
OZN62_13705	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OZN62_13710	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OZN62_13715	COG0255	Belongs to the universal ribosomal protein uL29 family
OZN62_13720	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OZN62_13725	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OZN62_13730	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OZN62_13735	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OZN62_13740	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OZN62_13745	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OZN62_13750	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OZN62_13755	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OZN62_13760	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
OZN62_13765	COG1841	ribosomal large subunit assembly
OZN62_13770	COG0200	Binds to the 23S rRNA
OZN62_13775	COG0201	protein transport
OZN62_13780	COG0563	adenylate kinase activity
OZN62_13790	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OZN62_13795	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OZN62_13800	COG0202	RNA polymerase activity
OZN62_13805	COG0203	ribosomal protein L17
OZN62_13815	COG1505	serine-type exopeptidase activity
OZN62_13830	COG2860	membrane
OZN62_13850	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OZN62_13855	COG0508	dehydrogenase complex catalyzes the overall conversion of
OZN62_13865	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OZN62_13870	COG0039	L-malate dehydrogenase activity
OZN62_13875	COG3300	MHYT domain
OZN62_13875	COG5001	Diguanylate cyclase
OZN62_13905	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
OZN62_13910	COG0339	signal peptide processing
OZN62_13920	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester