locus-tag	class	description
AURMO_00001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AURMO_00002	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AURMO_00004	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AURMO_00005	COG0706	membrane insertase activity
AURMO_00007	COG0357	Ribosomal RNA small subunit methyltransferase G
AURMO_00008	COG1192	Involved in chromosome partitioning
AURMO_00010	COG1181	Belongs to the D-alanine--D-alanine ligase family
AURMO_00011	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AURMO_00012	COG3118	belongs to the thioredoxin family
AURMO_00013	COG0492	ferredoxin-NADP+ reductase activity
AURMO_00015	COG0617	tRNA 3'-terminal CCA addition
AURMO_00016	COG0360	Binds together with S18 to 16S ribosomal RNA
AURMO_00018	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AURMO_00019	COG0359	binds to the 23S rRNA
AURMO_00020	COG0305	Participates in initiation and elongation during chromosome replication
AURMO_00023	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AURMO_00028	COG0022	dehydrogenase e1 component
AURMO_00029	COG0508	dehydrogenase complex catalyzes the overall conversion of
AURMO_00030	COG3177	Filamentation induced by cAMP protein fic
AURMO_00031	COG1280	lysine exporter protein (LysE YggA)
AURMO_00033	COG1522	sequence-specific DNA binding
AURMO_00034	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AURMO_00044	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AURMO_00046	COG2814	Major facilitator Superfamily
AURMO_00048	COG1028	Short-chain dehydrogenase reductase Sdr
AURMO_00053	COG1129	ABC transporter
AURMO_00054	COG1172	Belongs to the binding-protein-dependent transport system permease family
AURMO_00057	COG1012	belongs to the aldehyde dehydrogenase family
AURMO_00061	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AURMO_00062	COG1492	cobalamin metabolic process
AURMO_00063	COG3104	oligopeptide transport
AURMO_00064	COG2267	carboxylic ester hydrolase activity
AURMO_00066	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AURMO_00073	COG1132	(ABC) transporter
AURMO_00076	COG1216	Glycosyl transferase, family 2
AURMO_00081	COG0477	Major facilitator Superfamily
AURMO_00082	COG1733	regulation of RNA biosynthetic process
AURMO_00085	COG0077	Prephenate dehydratase
AURMO_00086	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AURMO_00087	COG0561	phosphatase activity
AURMO_00089	COG1316	TRANSCRIPTIONal
AURMO_00092	COG0513	Belongs to the DEAD box helicase family
AURMO_00094	COG1960	acyl-CoA dehydrogenase activity
AURMO_00098	COG2326	polyphosphate kinase activity
AURMO_00099	COG0412	Dienelactone hydrolase
AURMO_00100	COG0646	methionine synthase
AURMO_00100	COG1410	methionine synthase
AURMO_00103	COG3845	ABC transporter
AURMO_00108	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AURMO_00111	COG0181	hydroxymethylbilane synthase activity
AURMO_00112	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AURMO_00113	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AURMO_00122	COG2801	Transposase and inactivated derivatives
AURMO_00123	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AURMO_00124	COG0037	tRNA processing
AURMO_00126	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AURMO_00127	COG0302	gtp cyclohydrolase
AURMO_00129	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AURMO_00130	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AURMO_00133	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AURMO_00134	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AURMO_00136	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AURMO_00137	COG0667	Aldo Keto reductase
AURMO_00142	COG0542	response to heat
AURMO_00143	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AURMO_00148	COG2184	nucleotidyltransferase activity
AURMO_00152	COG2197	response regulator
AURMO_00153	COG4585	Histidine kinase
AURMO_00154	COG1136	(ABC) transporter
AURMO_00155	COG1136	(ABC) transporter
AURMO_00155	COG0577	efflux transmembrane transporter activity
AURMO_00156	COG4886	Leucine-rich repeat (LRR) protein
AURMO_00158	COG2197	response regulator
AURMO_00177	COG0085	RNA polymerase activity
AURMO_00178	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AURMO_00180	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AURMO_00181	COG0049	tRNA binding
AURMO_00182	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AURMO_00183	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AURMO_00186	COG0659	secondary active sulfate transmembrane transporter activity
AURMO_00187	COG0051	transcription antitermination factor activity, RNA binding
AURMO_00188	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AURMO_00189	COG0088	Forms part of the polypeptide exit tunnel
AURMO_00190	COG0089	rRNA binding
AURMO_00191	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AURMO_00192	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AURMO_00193	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AURMO_00194	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AURMO_00195	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AURMO_00196	COG0255	Belongs to the universal ribosomal protein uL29 family
AURMO_00197	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AURMO_00198	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AURMO_00199	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AURMO_00200	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AURMO_00201	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AURMO_00202	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AURMO_00203	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AURMO_00204	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AURMO_00205	COG1841	ribosomal large subunit assembly
AURMO_00206	COG0200	Binds to the 23S rRNA
AURMO_00208	COG0563	adenylate kinase activity
AURMO_00209	COG0024	Methionine aminopeptidase
AURMO_00211	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AURMO_00212	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AURMO_00213	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AURMO_00214	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AURMO_00215	COG0202	RNA polymerase activity
AURMO_00216	COG0203	ribosomal protein L17
AURMO_00217	COG0101	tRNA pseudouridine synthase activity
AURMO_00218	COG3550	peptidyl-serine autophosphorylation
AURMO_00220	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AURMO_00221	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AURMO_00222	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AURMO_00223	COG1072	(Pantothenic acid kinase))
AURMO_00224	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AURMO_00225	COG0736	holo-[acyl-carrier-protein] synthase activity
AURMO_00226	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AURMO_00227	COG0802	atpase or kinase
AURMO_00228	COG1214	PFAM Peptidase M22, glycoprotease
AURMO_00228	COG0456	acetyltransferase
AURMO_00229	COG0456	acetyltransferase
AURMO_00229	COG1214	PFAM Peptidase M22, glycoprotease
AURMO_00230	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AURMO_00235	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AURMO_00242	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AURMO_00242	COG0519	Catalyzes the synthesis of GMP from XMP
AURMO_00246	COG0516	GMP reductase activity
AURMO_00250	COG0411	ABC transporter
AURMO_00257	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AURMO_00283	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AURMO_00290	COG2132	Multicopper oxidase
AURMO_00298	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AURMO_00299	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AURMO_00302	COG0579	oxidoreductase
AURMO_00306	COG1435	thymidine kinase activity
AURMO_00307	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AURMO_00312	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AURMO_00315	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AURMO_00321	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AURMO_00321	COG1754	DNA topoisomerase type I activity
AURMO_00322	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AURMO_00323	COG0470	DNA polymerase III
AURMO_00328	COG2837	iron assimilation
AURMO_00331	COG2801	Transposase and inactivated derivatives
AURMO_00331	COG3415	Transposase
AURMO_00332	COG2409	Drug exporters of the RND superfamily
AURMO_00334	COG2801	Transposase and inactivated derivatives
AURMO_00336	COG1132	(ABC) transporter
AURMO_00338	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AURMO_00339	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AURMO_00339	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AURMO_00343	COG0180	Tryptophanyl-tRNA synthetase
AURMO_00344	COG0708	Exodeoxyribonuclease III
AURMO_00348	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AURMO_00349	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AURMO_00349	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AURMO_00349	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AURMO_00350	COG1105	Belongs to the carbohydrate kinase PfkB family
AURMO_00351	COG1349	DNA-binding transcription factor activity
AURMO_00353	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AURMO_00354	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AURMO_00355	COG1053	succinate dehydrogenase
AURMO_00357	COG2009	succinate dehydrogenase
AURMO_00358	COG0662	Cupin 2, conserved barrel domain protein
AURMO_00358	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AURMO_00359	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AURMO_00362	COG4770	biotin carboxylase activity
AURMO_00363	COG0424	maF-like protein
AURMO_00364	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AURMO_00366	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AURMO_00369	COG0463	Glycosyl transferase, family 2
AURMO_00373	COG1316	TRANSCRIPTIONal
AURMO_00376	COG1960	acyl-CoA dehydrogenase activity
AURMO_00377	COG1482	cell wall glycoprotein biosynthetic process
AURMO_00383	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AURMO_00384	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AURMO_00386	COG5000	phosphorelay sensor kinase activity
AURMO_00386	COG5002	protein histidine kinase activity
AURMO_00387	COG5401	PFAM Sporulation and spore germination
AURMO_00390	COG0653	protein targeting
AURMO_00404	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AURMO_00404	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AURMO_00406	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AURMO_00407	COG1024	Enoyl-CoA hydratase
AURMO_00407	COG1250	3-hydroxyacyl-CoA dehydrogenase
AURMO_00412	COG3594	Acyltransferase
AURMO_00413	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AURMO_00414	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AURMO_00421	COG1088	dTDP-glucose 4,6-dehydratase activity
AURMO_00423	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AURMO_00424	COG1162	GTPase activity
AURMO_00425	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AURMO_00426	COG1595	DNA-templated transcription, initiation
AURMO_00428	COG2826	transposase and inactivated derivatives, IS30 family
AURMO_00429	COG0508	dehydrogenase complex catalyzes the overall conversion of
AURMO_00429	COG0567	Dehydrogenase, E1 component
AURMO_00434	COG1132	(ABC) transporter
AURMO_00449	COG2801	Transposase and inactivated derivatives
AURMO_00449	COG3415	Transposase
AURMO_00452	COG0018	arginyl-trna synthetase
AURMO_00454	COG0460	homoserine dehydrogenase
AURMO_00456	COG0083	homoserine kinase activity
AURMO_00459	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AURMO_00460	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AURMO_00463	COG1045	serine acetyltransferase
AURMO_00466	COG2890	protein-(glutamine-N5) methyltransferase activity
AURMO_00468	COG0009	L-threonylcarbamoyladenylate synthase
AURMO_00469	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AURMO_00471	COG3177	Filamentation induced by cAMP protein fic
AURMO_00472	COG0356	it plays a direct role in the translocation of protons across the membrane
AURMO_00473	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AURMO_00474	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AURMO_00475	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AURMO_00476	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AURMO_00477	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AURMO_00478	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AURMO_00479	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AURMO_00490	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AURMO_00491	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AURMO_00492	COG0750	zinc metalloprotease
AURMO_00493	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AURMO_00496	COG0442	prolyl-tRNA aminoacylation
AURMO_00499	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AURMO_00500	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AURMO_00506	COG2884	Cell division ATP-binding protein ftsE
AURMO_00508	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AURMO_00512	COG0386	Belongs to the glutathione peroxidase family
AURMO_00515	COG0483	inositol monophosphate 1-phosphatase activity
AURMO_00517	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AURMO_00520	COG1228	amidohydrolase
AURMO_00521	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AURMO_00524	COG2076	Multidrug Resistance protein
AURMO_00527	COG0702	epimerase
AURMO_00532	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AURMO_00534	COG2267	carboxylic ester hydrolase activity
AURMO_00535	COG0306	phosphate transporter
AURMO_00537	COG2252	PERMEase
AURMO_00541	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AURMO_00553	COG3480	Lon protease (S16) C-terminal proteolytic domain
AURMO_00554	COG1615	UPF0182 protein
AURMO_00555	COG1271	oxidase subunit
AURMO_00556	COG1294	oxidase, subunit
AURMO_00557	COG4988	ABC transporter
AURMO_00558	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AURMO_00560	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AURMO_00561	COG1082	Xylose isomerase domain protein TIM barrel
AURMO_00562	COG0129	dihydroxy-acid dehydratase activity
AURMO_00564	COG0440	acetolactate synthase activity
AURMO_00565	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AURMO_00569	COG0473	3-isopropylmalate dehydrogenase activity
AURMO_00570	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AURMO_00571	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AURMO_00573	COG1597	lipid kinase activity
AURMO_00575	COG0861	Integral membrane protein TerC family
AURMO_00576	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AURMO_00577	COG0066	3-isopropylmalate dehydratase activity
AURMO_00578	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AURMO_00580	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AURMO_00581	COG1181	Belongs to the D-alanine--D-alanine ligase family
AURMO_00584	COG0742	ribosomal rna small subunit methyltransferase
AURMO_00586	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AURMO_00587	COG0552	protein localization to endoplasmic reticulum
AURMO_00589	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AURMO_00591	COG0228	four-way junction DNA binding
AURMO_00592	COG1837	Belongs to the UPF0109 family
AURMO_00593	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AURMO_00594	COG0336	Belongs to the RNA methyltransferase TrmD family
AURMO_00595	COG0335	large ribosomal subunit rRNA binding
AURMO_00597	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AURMO_00600	COG4974	Belongs to the 'phage' integrase family
AURMO_00606	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
AURMO_00607	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AURMO_00608	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AURMO_00613	COG0366	Alpha amylase catalytic
AURMO_00614	COG1674	ftsk spoiiie
AURMO_00616	COG1546	Belongs to the CinA family
AURMO_00616	COG1058	Belongs to the CinA family
AURMO_00617	COG1396	sequence-specific DNA binding
AURMO_00619	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AURMO_00620	COG2137	regulation of response to DNA damage stimulus
AURMO_00622	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AURMO_00623	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AURMO_00624	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AURMO_00626	COG2813	Specifically methylates the guanine in position
AURMO_00629	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AURMO_00634	COG0495	leucyl-tRNA aminoacylation
AURMO_00635	COG2815	serine threonine protein kinase
AURMO_00635	COG0515	serine threonine protein kinase
AURMO_00641	COG2001	Belongs to the MraZ family
AURMO_00642	COG0275	rRNA processing
AURMO_00644	COG0768	penicillin binding
AURMO_00645	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AURMO_00647	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AURMO_00648	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AURMO_00650	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AURMO_00651	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AURMO_00653	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AURMO_00654	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AURMO_00655	COG1799	cell septum assembly
AURMO_00658	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AURMO_00660	COG1660	Displays ATPase and GTPase activities
AURMO_00661	COG1481	regulation of sporulation
AURMO_00664	COG0126	phosphoglycerate kinase activity
AURMO_00665	COG0149	triose-phosphate isomerase activity
AURMO_00666	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AURMO_00668	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AURMO_00669	COG3415	Transposase
AURMO_00669	COG2801	Transposase and inactivated derivatives
AURMO_00670	COG0363	glucosamine-6-phosphate deaminase activity
AURMO_00674	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AURMO_00676	COG0109	protoheme IX farnesyltransferase activity
AURMO_00677	COG1612	heme a metabolic process
AURMO_00678	COG0719	Fe-S assembly protein
AURMO_00681	COG0396	ATPase activity
AURMO_00682	COG2151	metal-sulfur cluster biosynthetic enzyme
AURMO_00685	COG0488	(ABC) transporter
AURMO_00686	COG2860	membrane
AURMO_00687	COG1381	Involved in DNA repair and RecF pathway recombination
AURMO_00688	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AURMO_00693	COG0358	DNA primase activity
AURMO_00698	COG0242	peptide deformylase activity
AURMO_00699	COG0697	spore germination
AURMO_00700	COG0438	transferase activity, transferring glycosyl groups
AURMO_00711	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AURMO_00713	COG0582	viral genome integration into host DNA
AURMO_00719	COG2801	Transposase and inactivated derivatives
AURMO_00721	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AURMO_00722	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AURMO_00725	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AURMO_00729	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AURMO_00731	COG0406	alpha-ribazole phosphatase activity
AURMO_00731	COG0328	RNA-DNA hybrid ribonuclease activity
AURMO_00735	COG2801	Transposase and inactivated derivatives
AURMO_00735	COG3415	Transposase
AURMO_00736	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AURMO_00737	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AURMO_00737	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AURMO_00739	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AURMO_00740	COG0174	glutamine synthetase
AURMO_00743	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AURMO_00744	COG0321	lipoyl(octanoyl) transferase activity
AURMO_00746	COG0508	dehydrogenase complex catalyzes the overall conversion of
AURMO_00747	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AURMO_00748	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AURMO_00750	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AURMO_00751	COG2826	transposase and inactivated derivatives, IS30 family
AURMO_00754	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AURMO_00759	COG0756	dUTP diphosphatase activity
AURMO_00762	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AURMO_00763	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AURMO_00764	COG1250	3-hydroxyacyl-CoA dehydrogenase
AURMO_00764	COG1024	Enoyl-CoA hydratase
AURMO_00765	COG0183	Belongs to the thiolase family
AURMO_00777	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AURMO_00779	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
AURMO_00780	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AURMO_00781	COG0217	transcriptional regulatory protein
AURMO_00782	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AURMO_00783	COG0632	four-way junction helicase activity
AURMO_00784	COG2255	four-way junction helicase activity
AURMO_00786	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AURMO_00787	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AURMO_00788	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AURMO_00793	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AURMO_00795	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AURMO_00796	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AURMO_00798	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AURMO_00799	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AURMO_00800	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AURMO_00801	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AURMO_00802	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AURMO_00803	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AURMO_00804	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AURMO_00805	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AURMO_00806	COG0540	Belongs to the ATCase OTCase family
AURMO_00807	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AURMO_00809	COG0505	Belongs to the CarA family
AURMO_00810	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AURMO_00811	COG0284	orotidine-5'-phosphate decarboxylase activity
AURMO_00812	COG0194	GDP metabolic process
AURMO_00813	COG1758	RNA polymerase activity
AURMO_00815	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AURMO_00817	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AURMO_00820	COG0140	phosphoribosyl-ATP diphosphatase activity
AURMO_00821	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AURMO_00822	COG0107	imidazoleglycerol-phosphate synthase activity
AURMO_00827	COG0134	indole-3-glycerol-phosphate synthase activity
AURMO_00828	COG0133	tryptophan synthase activity
AURMO_00829	COG0159	tryptophan synthase activity
AURMO_00830	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AURMO_00831	COG0070	glutamate synthase
AURMO_00831	COG0069	glutamate synthase activity
AURMO_00831	COG0067	glutamate synthase
AURMO_00833	COG0469	pyruvate kinase activity
AURMO_00836	COG2050	protein possibly involved in aromatic compounds catabolism
AURMO_00838	COG0539	negative regulation of cytoplasmic translation
AURMO_00839	COG0237	dephospho-CoA kinase activity
AURMO_00840	COG0556	nucleotide-excision repair
AURMO_00842	COG0322	excinuclease ABC activity
AURMO_00843	COG0584	glycerophosphoryl diester phosphodiesterase
AURMO_00844	COG1028	Short-chain dehydrogenase reductase Sdr
AURMO_00845	COG0494	nUDIX hydrolase
AURMO_00849	COG0697	spore germination
AURMO_00850	COG0738	Major facilitator superfamily
AURMO_00851	COG0738	Major facilitator superfamily
AURMO_00852	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AURMO_00853	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AURMO_00854	COG1845	cytochrome c oxidase, subunit III
AURMO_00855	COG2010	Cytochrome c
AURMO_00856	COG0723	plastoquinol--plastocyanin reductase activity
AURMO_00857	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AURMO_00860	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AURMO_00861	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AURMO_00863	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AURMO_00865	COG0167	dihydroorotate dehydrogenase activity
AURMO_00866	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AURMO_00867	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AURMO_00868	COG0587	DNA-directed DNA polymerase activity
AURMO_00871	COG0805	protein transport
AURMO_00872	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AURMO_00875	COG0545	Peptidyl-prolyl cis-trans isomerase
AURMO_00877	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AURMO_00879	COG1968	undecaprenyl-diphosphatase activity
AURMO_00888	COG0254	rRNA binding
AURMO_00889	COG1119	ATPase activity
AURMO_00890	COG0297	glycogen (starch) synthase activity
AURMO_00891	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AURMO_00892	COG0560	Phosphoserine phosphatase
AURMO_00892	COG3830	Belongs to the UPF0237 family
AURMO_00893	COG1028	Short-chain dehydrogenase reductase Sdr
AURMO_00896	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AURMO_00897	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AURMO_00899	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AURMO_00901	COG0537	adenosine 5'-monophosphoramidase activity
AURMO_00903	COG0484	heat shock protein binding
AURMO_00904	COG1420	regulation of RNA biosynthetic process
AURMO_00907	COG0481	GTPase activity
AURMO_00908	COG0268	Binds directly to 16S ribosomal RNA
AURMO_00911	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AURMO_00912	COG4129	membrane
AURMO_00913	COG1472	Belongs to the glycosyl hydrolase 3 family
AURMO_00915	COG0446	pyridine nucleotide-disulphide oxidoreductase
AURMO_00917	COG3842	ATPase activity
AURMO_00919	COG0604	alcohol dehydrogenase
AURMO_00920	COG2824	Alkylphosphonate utilization operon protein PhnA
AURMO_00921	COG0698	ribose 5-phosphate isomerase
AURMO_00923	COG0799	negative regulation of ribosome biogenesis
AURMO_00925	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AURMO_00927	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AURMO_00928	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AURMO_00929	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AURMO_00930	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AURMO_00931	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AURMO_00932	COG1530	ribonuclease E activity
AURMO_00934	COG0477	Major facilitator Superfamily
AURMO_00935	COG0105	UTP biosynthetic process
AURMO_00937	COG0285	dihydrofolate synthase activity
AURMO_00938	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AURMO_00939	COG0525	valine-tRNA ligase activity
AURMO_00943	COG2801	Transposase and inactivated derivatives
AURMO_00944	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AURMO_00948	COG0531	amino acid
AURMO_00949	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AURMO_00951	COG1940	carbohydrate kinase activity
AURMO_00955	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AURMO_00956	COG1192	Involved in chromosome partitioning
AURMO_00959	COG1716	ATPase activity
AURMO_00960	COG0513	Belongs to the DEAD box helicase family
AURMO_00962	COG3046	protein related to deoxyribodipyrimidine photolyase
AURMO_00963	COG0697	spore germination
AURMO_00966	COG0697	spore germination
AURMO_00968	COG1280	lysine exporter protein (LysE YggA)
AURMO_00969	COG4702	Belongs to the UPF0303 family
AURMO_00972	COG0477	Major facilitator Superfamily
AURMO_00973	COG0402	S-adenosylhomocysteine deaminase activity
AURMO_00979	COG1160	GTP binding
AURMO_00980	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AURMO_00983	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AURMO_00984	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AURMO_00986	COG4974	Belongs to the 'phage' integrase family
AURMO_00988	COG0504	CTP synthase activity
AURMO_00989	COG0497	DNA recombination
AURMO_00990	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AURMO_00994	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AURMO_00995	COG2079	MmgE PrpD family protein
AURMO_00996	COG1802	Transcriptional regulator
AURMO_00999	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AURMO_01000	COG2801	Transposase and inactivated derivatives
AURMO_01007	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AURMO_01008	COG0165	Argininosuccinate lyase
AURMO_01009	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AURMO_01010	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AURMO_01011	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AURMO_01012	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AURMO_01014	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AURMO_01014	COG0072	phenylalanine-tRNA ligase activity
AURMO_01015	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AURMO_01016	COG2337	Toxic component of a toxin-antitoxin (TA) module
AURMO_01018	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AURMO_01019	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AURMO_01020	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AURMO_01021	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AURMO_01024	COG2409	Drug exporters of the RND superfamily
AURMO_01027	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AURMO_01028	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AURMO_01029	COG0131	Imidazoleglycerol-phosphate dehydratase
AURMO_01030	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AURMO_01032	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AURMO_01033	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AURMO_01034	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AURMO_01036	COG0740	serine-type endopeptidase activity
AURMO_01037	COG0740	serine-type endopeptidase activity
AURMO_01041	COG2826	transposase and inactivated derivatives, IS30 family
AURMO_01047	COG0544	peptidyl-prolyl cis-trans isomerase activity
AURMO_01050	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AURMO_01051	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AURMO_01059	COG0668	transmembrane transport
AURMO_01062	COG1946	Acyl-CoA thioesterase
AURMO_01064	COG0824	Thioesterase
AURMO_01068	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AURMO_01073	COG1012	belongs to the aldehyde dehydrogenase family
AURMO_01074	COG2801	Transposase and inactivated derivatives
AURMO_01076	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AURMO_01081	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AURMO_01082	COG1122	ATPase activity
AURMO_01083	COG4721	ABC-type cobalt transport system, permease component
AURMO_01086	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AURMO_01087	COG0154	amidase activity
AURMO_01088	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AURMO_01090	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AURMO_01091	COG0482	sulfurtransferase activity
AURMO_01094	COG0366	Alpha amylase catalytic
AURMO_01095	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AURMO_01099	COG0628	permease
AURMO_01104	COG0575	Belongs to the CDS family
AURMO_01105	COG0233	cytoplasmic translational termination
AURMO_01106	COG0528	UMP kinase activity
AURMO_01107	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AURMO_01108	COG0052	Belongs to the universal ribosomal protein uS2 family
AURMO_01110	COG2814	Major facilitator Superfamily
AURMO_01113	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AURMO_01115	COG0612	Peptidase, M16
AURMO_01116	COG0667	Aldo Keto reductase
AURMO_01117	COG1185	polyribonucleotide nucleotidyltransferase activity
AURMO_01118	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AURMO_01122	COG1872	DUF167
AURMO_01124	COG0545	Peptidyl-prolyl cis-trans isomerase
AURMO_01128	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AURMO_01129	COG1012	belongs to the aldehyde dehydrogenase family
AURMO_01130	COG1028	Short-chain dehydrogenase reductase Sdr
AURMO_01131	COG2186	Transcriptional regulator
AURMO_01132	COG0531	amino acid
AURMO_01134	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AURMO_01135	COG1027	Aspartate ammonia-lyase
AURMO_01136	COG1012	belongs to the aldehyde dehydrogenase family
AURMO_01137	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AURMO_01138	COG0196	riboflavin kinase activity
AURMO_01141	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AURMO_01148	COG0714	Associated with various cellular activities
AURMO_01151	COG0631	protein serine/threonine phosphatase activity
AURMO_01154	COG1414	Transcriptional regulator
AURMO_01158	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AURMO_01159	COG0571	ribonuclease III activity
AURMO_01160	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AURMO_01165	COG0586	Pfam SNARE associated Golgi protein
AURMO_01166	COG0384	phenazine biosynthesis protein PhzF
AURMO_01168	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AURMO_01169	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AURMO_01170	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AURMO_01172	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AURMO_01175	COG1960	acyl-CoA dehydrogenase activity
AURMO_01180	COG0513	Belongs to the DEAD box helicase family
AURMO_01183	COG0613	PHP domain protein
AURMO_01184	COG0006	proline dipeptidase activity
AURMO_01186	COG0583	DNA-binding transcription factor activity
AURMO_01188	COG2239	Acts as a magnesium transporter
AURMO_01191	COG1012	belongs to the aldehyde dehydrogenase family
AURMO_01193	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AURMO_01194	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AURMO_01195	COG2818	Glycosylase
AURMO_01197	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AURMO_01201	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AURMO_01219	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AURMO_01219	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AURMO_01220	COG0509	glycine decarboxylation via glycine cleavage system
AURMO_01221	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AURMO_01224	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AURMO_01225	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AURMO_01227	COG1104	cysteine desulfurase activity
AURMO_01234	COG2801	Transposase and inactivated derivatives
AURMO_01236	COG1028	Short-chain dehydrogenase reductase Sdr
AURMO_01238	COG0300	oxidoreductase activity
AURMO_01242	COG0012	GTP binding
AURMO_01246	COG1322	Protein conserved in bacteria
AURMO_01249	COG0191	fructose-bisphosphate aldolase activity
AURMO_01251	COG1063	alcohol dehydrogenase
AURMO_01252	COG0246	Mannitol dehydrogenase
AURMO_01253	COG0395	ABC-type sugar transport system, permease component
AURMO_01257	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AURMO_01258	COG1570	exodeoxyribonuclease VII activity
AURMO_01259	COG1722	exodeoxyribonuclease VII activity
AURMO_01261	COG0288	reversible hydration of carbon dioxide
AURMO_01262	COG0114	fumarate hydratase activity
AURMO_01263	COG0667	Aldo Keto reductase
AURMO_01265	COG2801	Transposase and inactivated derivatives
AURMO_01271	COG2159	amidohydrolase
AURMO_01273	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AURMO_01274	COG1414	Transcriptional regulator
AURMO_01285	COG3959	Transketolase, thiamine diphosphate binding domain
AURMO_01287	COG1063	alcohol dehydrogenase
AURMO_01288	COG1129	ABC transporter
AURMO_01289	COG1172	Belongs to the binding-protein-dependent transport system permease family
AURMO_01291	COG1028	Short-chain dehydrogenase reductase Sdr
AURMO_01292	COG1082	Xylose isomerase domain protein TIM barrel
AURMO_01301	COG0633	Ferredoxin
AURMO_01302	COG1028	Short-chain dehydrogenase reductase Sdr
AURMO_01305	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AURMO_01305	COG0574	Belongs to the PEP-utilizing enzyme family
AURMO_01307	COG1414	Transcriptional regulator
AURMO_01311	COG2301	Belongs to the HpcH HpaI aldolase family
AURMO_01312	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AURMO_01314	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AURMO_01315	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AURMO_01316	COG3177	Filamentation induced by cAMP protein fic
AURMO_01321	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AURMO_01322	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AURMO_01324	COG1704	LemA family
AURMO_01327	COG2161	toxin-antitoxin pair type II binding
AURMO_01328	COG2026	Addiction module toxin, RelE StbE family
AURMO_01334	COG0148	phosphopyruvate hydratase activity
AURMO_01335	COG0124	histidyl-tRNA synthetase
AURMO_01338	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AURMO_01340	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AURMO_01343	COG0193	aminoacyl-tRNA hydrolase activity
AURMO_01344	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AURMO_01346	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AURMO_01350	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AURMO_01351	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AURMO_01359	COG0488	(ABC) transporter
AURMO_01360	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AURMO_01361	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AURMO_01362	COG0084	hydrolase, TatD family'
AURMO_01363	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AURMO_01368	COG1760	l-serine dehydratase
AURMO_01374	COG1937	Protein conserved in bacteria
AURMO_01375	COG2217	Heavy metal translocating P-type atpase
AURMO_01378	COG0477	Major facilitator Superfamily
AURMO_01379	COG1643	Atp-dependent helicase
AURMO_01381	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AURMO_01383	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AURMO_01383	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AURMO_01385	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AURMO_01386	COG0259	pyridoxamine-phosphate oxidase activity
AURMO_01388	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AURMO_01398	COG0581	inorganic phosphate transmembrane transporter activity
AURMO_01400	COG2815	serine threonine protein kinase
AURMO_01400	COG0515	serine threonine protein kinase
AURMO_01406	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AURMO_01419	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AURMO_01421	COG1278	Cold shock
AURMO_01425	COG0745	RESPONSE REGULATOR receiver
AURMO_01426	COG5002	protein histidine kinase activity
AURMO_01428	COG0459	protein refolding
AURMO_01429	COG1470	cell adhesion involved in biofilm formation
AURMO_01430	COG1278	Cold shock
AURMO_01435	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AURMO_01436	COG0215	cysteine-tRNA ligase activity
AURMO_01437	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AURMO_01437	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AURMO_01440	COG0588	phosphoglycerate mutase activity
AURMO_01444	COG0745	RESPONSE REGULATOR receiver
AURMO_01445	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AURMO_01449	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AURMO_01452	COG2197	response regulator
AURMO_01457	COG1741	Belongs to the pirin family
AURMO_01459	COG2843	Capsule synthesis protein
AURMO_01462	COG2801	Transposase and inactivated derivatives
AURMO_01462	COG3415	Transposase
AURMO_01463	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AURMO_01464	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AURMO_01466	COG3384	dioxygenase
AURMO_01472	COG2217	Heavy metal translocating P-type atpase
AURMO_01473	COG0081	regulation of translation
AURMO_01474	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AURMO_01476	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AURMO_01478	COG0436	Aminotransferase
AURMO_01480	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AURMO_01482	COG2030	dehydratase
AURMO_01483	COG0076	glutamate decarboxylase activity
AURMO_01484	COG2957	Belongs to the agmatine deiminase family
AURMO_01490	COG1136	(ABC) transporter
AURMO_01494	COG1064	alcohol dehydrogenase
AURMO_01498	COG2078	PFAM AMMECR1 domain protein
AURMO_01498	COG3885	ferrous iron binding
AURMO_01500	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AURMO_01501	COG1846	Transcriptional regulator
AURMO_01505	COG0174	glutamine synthetase
AURMO_01507	COG1834	amidinotransferase
AURMO_01508	COG0138	bifunctional purine biosynthesis protein purh
AURMO_01510	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AURMO_01516	COG0045	succinate-CoA ligase (ADP-forming) activity
AURMO_01519	COG0584	glycerophosphoryl diester phosphodiesterase
AURMO_01523	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AURMO_01525	COG1012	belongs to the aldehyde dehydrogenase family
AURMO_01526	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AURMO_01528	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AURMO_01534	COG2801	Transposase and inactivated derivatives
AURMO_01537	COG0137	argininosuccinate synthase activity
AURMO_01538	COG0673	inositol 2-dehydrogenase activity
AURMO_01539	COG1940	carbohydrate kinase activity
AURMO_01540	COG2115	Belongs to the xylose isomerase family
AURMO_01541	COG1070	Carbohydrate kinase
AURMO_01542	COG4213	ABC transporter substrate-binding protein
AURMO_01544	COG4214	carbohydrate transport
AURMO_01548	COG0222	ribosome binding
AURMO_01549	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AURMO_01550	COG1105	Belongs to the carbohydrate kinase PfkB family
AURMO_01551	COG2205	protein histidine kinase activity
AURMO_01552	COG0745	RESPONSE REGULATOR receiver
AURMO_01555	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AURMO_01558	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AURMO_01558	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AURMO_01559	COG0604	alcohol dehydrogenase
AURMO_01560	COG0076	glutamate decarboxylase activity
AURMO_01561	COG1132	(ABC) transporter
AURMO_01562	COG1132	(ABC) transporter
AURMO_01570	COG0366	Alpha amylase catalytic
AURMO_01571	COG0739	heme binding
AURMO_01572	COG0483	inositol monophosphate 1-phosphatase activity
AURMO_01575	COG1228	amidohydrolase
AURMO_01577	COG2838	Isocitrate dehydrogenase
AURMO_01582	COG1666	GTP binding
AURMO_01585	COG2272	Belongs to the type-B carboxylesterase lipase family
AURMO_01589	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AURMO_01591	COG2826	transposase and inactivated derivatives, IS30 family
AURMO_01592	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AURMO_01599	COG0640	Transcriptional regulator
AURMO_01603	COG0151	Belongs to the GarS family
AURMO_01604	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AURMO_01605	COG2364	Membrane
AURMO_01609	COG2132	Multicopper oxidase
AURMO_01612	COG0438	transferase activity, transferring glycosyl groups
AURMO_01620	COG3483	tryptophan 2,3-dioxygenase activity
AURMO_01623	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AURMO_01624	COG0047	phosphoribosylformylglycinamidine synthase activity
AURMO_01626	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AURMO_01629	COG1605	Chorismate mutase
AURMO_01629	COG0287	Prephenate dehydrogenase
AURMO_01630	COG0697	spore germination
AURMO_01631	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AURMO_01632	COG0500	methyltransferase
AURMO_01633	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AURMO_01636	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AURMO_01637	COG0531	amino acid
AURMO_01638	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AURMO_01641	COG0730	response to heat
AURMO_01642	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AURMO_01643	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AURMO_01646	COG0142	geranyltranstransferase activity
AURMO_01647	COG2226	methyltransferase
AURMO_01649	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AURMO_01655	COG4948	Mandelate Racemase Muconate Lactonizing
AURMO_01656	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AURMO_01657	COG1333	cytochrome c biogenesis protein
AURMO_01658	COG0785	Cytochrome C biogenesis protein
AURMO_01659	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AURMO_01660	COG0406	alpha-ribazole phosphatase activity
AURMO_01661	COG0017	Asparaginyl-tRNA synthetase
AURMO_01666	COG0640	Transcriptional regulator
AURMO_01667	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AURMO_01668	COG0569	domain protein
AURMO_01669	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AURMO_01671	COG0590	tRNA wobble adenosine to inosine editing
AURMO_01673	COG0415	Belongs to the DNA photolyase family
AURMO_01675	COG1305	Transglutaminase-like
AURMO_01680	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AURMO_01683	COG0300	oxidoreductase activity
AURMO_01685	COG1305	Transglutaminase-like
AURMO_01689	COG0300	oxidoreductase activity
AURMO_01698	COG0542	response to heat
AURMO_01699	COG2813	Specifically methylates the guanine in position
AURMO_01702	COG0789	Transcriptional regulator
AURMO_01703	COG0484	heat shock protein binding
AURMO_01704	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AURMO_01705	COG0443	Heat shock 70 kDa protein
AURMO_01708	COG1396	sequence-specific DNA binding
AURMO_01709	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
AURMO_01716	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AURMO_01719	COG0717	Belongs to the dCTP deaminase family
AURMO_01721	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AURMO_01724	COG0776	regulation of translation
AURMO_01725	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AURMO_01726	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AURMO_01727	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AURMO_01729	COG0735	belongs to the Fur family
AURMO_01730	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AURMO_01731	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AURMO_01732	COG1121	(ABC) transporter
AURMO_01733	COG0803	Belongs to the bacterial solute-binding protein 9 family
AURMO_01733	COG3443	Belongs to the bacterial solute-binding protein 9 family
AURMO_01740	COG0423	glycine-tRNA ligase activity
AURMO_01741	COG3590	peptidase
AURMO_01744	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
AURMO_01760	COG0745	RESPONSE REGULATOR receiver
AURMO_01761	COG5002	protein histidine kinase activity
AURMO_01762	COG1716	ATPase activity
AURMO_01766	COG0768	penicillin binding
AURMO_01767	COG0515	serine threonine protein kinase
AURMO_01768	COG0515	serine threonine protein kinase
AURMO_01768	COG2815	serine threonine protein kinase
AURMO_01771	COG3764	Sortase (surface protein transpeptidase)
AURMO_01773	COG0705	Rhomboid family
AURMO_01773	COG0457	Tetratricopeptide repeat
AURMO_01788	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AURMO_01789	COG0187	DNA topoisomerase II activity
AURMO_01791	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AURMO_01792	COG0592	DNA-directed DNA polymerase activity