locus-tag	class	description
LXB15_00005	COG0527	aspartate kinase activity
LXB15_00010	COG5285	phytanoyl-CoA dioxygenase
LXB15_00015	COG1917	Cupin 2, conserved barrel domain protein
LXB15_00020	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LXB15_00040	COG3454	Phosphonate metabolism
LXB15_00045	COG3639	organic phosphonate transmembrane transporter activity
LXB15_00050	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
LXB15_00065	COG4778	phosphonate C-P lyase system protein PhnL
LXB15_00070	COG4107	phosphonate C-P lyase system protein PhnK
LXB15_00075	COG2852	Protein conserved in bacteria
LXB15_00080	COG3627	carbon phosphorus lyase activity
LXB15_00090	COG1598	PFAM Uncharacterised protein family UPF0150
LXB15_00095	COG3626	phosphonate metabolism
LXB15_00105	COG3624	Phosphonate C-P lyase system protein PhnG
LXB15_00110	COG2188	Transcriptional regulator
LXB15_00115	COG3639	organic phosphonate transmembrane transporter activity
LXB15_00130	COG3454	Phosphonate metabolism
LXB15_00135	COG2188	Transcriptional regulator
LXB15_00140	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LXB15_00145	COG0363	glucosamine-6-phosphate deaminase activity
LXB15_00155	COG1028	Short-chain dehydrogenase reductase Sdr
LXB15_00175	COG1175	transmembrane transport
LXB15_00185	COG2390	Transcriptional regulator
LXB15_00195	COG4774	siderophore transport
LXB15_00210	COG1120	ATPase activity
LXB15_00240	COG4774	siderophore transport
LXB15_00245	COG1132	(ABC) transporter
LXB15_00260	COG0848	biopolymer transport protein
LXB15_00270	COG4774	siderophore transport
LXB15_00275	COG1959	2 iron, 2 sulfur cluster binding
LXB15_00285	COG1028	Short-chain dehydrogenase reductase Sdr
LXB15_00295	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LXB15_00305	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LXB15_00315	COG1959	2 iron, 2 sulfur cluster binding
LXB15_00320	COG2346	COG2346, Truncated hemoglobins
LXB15_00340	COG0559	Belongs to the binding-protein-dependent transport system permease family
LXB15_00365	COG3842	ATPase activity
LXB15_00380	COG3833	ABC-type maltose transport systems, permease component
LXB15_00385	COG2084	Dehydrogenase
LXB15_00390	COG2084	Dehydrogenase
LXB15_00395	COG1028	Short-chain dehydrogenase reductase Sdr
LXB15_00410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LXB15_00415	COG1028	Short-chain dehydrogenase reductase Sdr
LXB15_00420	COG0129	dihydroxy-acid dehydratase activity
LXB15_00425	COG2186	Transcriptional regulator
LXB15_00430	COG4213	ABC transporter substrate-binding protein
LXB15_00440	COG4214	carbohydrate transport
LXB15_00450	COG3734	2-keto-3-deoxy-galactonokinase
LXB15_00455	COG0800	Aldolase
LXB15_00465	COG2323	membrane
LXB15_00475	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LXB15_00475	COG3743	rRNA binding
LXB15_00480	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LXB15_00495	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LXB15_00500	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LXB15_00505	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LXB15_00510	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LXB15_00515	COG0799	negative regulation of ribosome biogenesis
LXB15_00520	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LXB15_00530	COG0793	Belongs to the peptidase S41A family
LXB15_00545	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LXB15_00555	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LXB15_00560	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LXB15_00570	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LXB15_00580	COG2354	Protein conserved in bacteria
LXB15_00595	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LXB15_00600	COG0783	Belongs to the Dps family
LXB15_00605	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LXB15_00615	COG0443	Heat shock 70 kDa protein
LXB15_00670	COG1121	(ABC) transporter
LXB15_00675	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LXB15_00680	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LXB15_00685	COG2954	triphosphatase activity
LXB15_00695	COG0183	Belongs to the thiolase family
LXB15_00700	COG1454	alcohol dehydrogenase
LXB15_00705	COG1028	Short-chain dehydrogenase reductase Sdr
LXB15_00710	COG0243	molybdopterin cofactor binding
LXB15_00715	COG2146	nitrite reductase [NAD(P)H] activity
LXB15_00720	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LXB15_00725	COG1116	anion transmembrane transporter activity
LXB15_00730	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LXB15_00735	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LXB15_00745	COG3707	response regulator
LXB15_00790	COG1566	PFAM secretion protein HlyD family protein
LXB15_00795	COG2814	Major facilitator Superfamily
LXB15_00885	COG2197	response regulator
LXB15_00925	COG2080	2 iron, 2 sulfur cluster binding
LXB15_00930	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
LXB15_00935	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LXB15_00940	COG5001	Diguanylate cyclase
LXB15_00940	COG5002	protein histidine kinase activity
LXB15_00940	COG3447	MASE1 domain protein
LXB15_00955	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LXB15_00965	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
LXB15_00990	COG0702	epimerase
LXB15_01000	COG2154	pterin-4-alpha-carbinolamine dehydratase
LXB15_01010	COG1229	Formylmethanofuran dehydrogenase subunit A
LXB15_01015	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
LXB15_01050	COG0411	ABC transporter
LXB15_01065	COG0829	nickel cation binding
LXB15_01070	COG0831	urea catabolic process
LXB15_01090	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
LXB15_01110	COG0804	urea catabolic process
LXB15_01125	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
LXB15_01130	COG0830	nickel cation binding
LXB15_01135	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LXB15_01145	COG4993	Dehydrogenase
LXB15_01150	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
LXB15_01155	COG4266	Belongs to the allantoicase family
LXB15_01160	COG3648	Uricase
LXB15_01160	COG3195	allantoin biosynthetic process
LXB15_01170	COG0546	phosphoglycolate phosphatase activity
LXB15_01175	COG2351	hydroxyisourate hydrolase activity
LXB15_01185	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LXB15_01195	COG3845	ABC transporter
LXB15_01200	COG4603	Belongs to the binding-protein-dependent transport system permease family
LXB15_01205	COG1079	Belongs to the binding-protein-dependent transport system permease family
LXB15_01220	COG0402	S-adenosylhomocysteine deaminase activity
LXB15_01230	COG0366	Alpha amylase catalytic
LXB15_01240	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LXB15_01245	COG0351	phosphomethylpyrimidine kinase
LXB15_01250	COG3706	GGDEF domain
LXB15_01260	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LXB15_01260	COG2308	Evidence 4 Homologs of previously reported genes of
LXB15_01280	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LXB15_01285	COG1640	4-alpha-glucanotransferase
LXB15_01300	COG0673	inositol 2-dehydrogenase activity
LXB15_01315	COG1028	Short-chain dehydrogenase reductase Sdr
LXB15_01320	COG0183	Belongs to the thiolase family
LXB15_01325	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
LXB15_01330	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LXB15_01335	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LXB15_01350	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LXB15_01365	COG2223	nitrite transmembrane transporter activity
LXB15_01370	COG1349	DNA-binding transcription factor activity
LXB15_01375	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LXB15_01390	COG4581	dead DEAH box helicase
LXB15_01400	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LXB15_01460	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LXB15_01500	COG1401	restriction endodeoxyribonuclease activity
LXB15_01530	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
LXB15_01555	COG1473	amidohydrolase
LXB15_01560	COG1686	Belongs to the peptidase S11 family
LXB15_01565	COG0523	cobalamin synthesis protein
LXB15_01580	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LXB15_01585	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LXB15_01595	COG2094	Belongs to the DNA glycosylase MPG family
LXB15_01600	COG0513	Belongs to the DEAD box helicase family
LXB15_01620	COG5001	Diguanylate cyclase
LXB15_01635	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LXB15_01640	COG0679	Auxin Efflux Carrier
LXB15_01665	COG2096	Adenosyltransferase
LXB15_01670	COG2086	electron transfer activity
LXB15_01675	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LXB15_01680	COG1250	3-hydroxyacyl-CoA dehydrogenase
LXB15_01685	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LXB15_01690	COG0165	Argininosuccinate lyase
LXB15_01700	COG0019	diaminopimelate decarboxylase activity
LXB15_01710	COG4566	intracellular signal transduction
LXB15_01715	COG0037	tRNA processing
LXB15_01715	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LXB15_01725	COG2884	Cell division ATP-binding protein ftsE
LXB15_01755	COG0287	Prephenate dehydrogenase
LXB15_01760	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LXB15_01765	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LXB15_01770	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LXB15_01785	COG2226	methyltransferase
LXB15_01790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LXB15_01810	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LXB15_01815	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LXB15_01820	COG0596	Alpha beta hydrolase
LXB15_01820	COG0508	dehydrogenase complex catalyzes the overall conversion of
LXB15_01860	COG0659	secondary active sulfate transmembrane transporter activity
LXB15_01865	COG4536	flavin adenine dinucleotide binding
LXB15_01870	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LXB15_01875	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LXB15_01890	COG0825	malonyl-CoA metabolic process
LXB15_01900	COG1393	Belongs to the ArsC family
LXB15_01905	COG0653	protein targeting
LXB15_01910	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LXB15_01915	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LXB15_01925	COG0494	nUDIX hydrolase
LXB15_01935	COG0656	L-ascorbic acid biosynthetic process
LXB15_01945	COG0542	response to heat
LXB15_01955	COG2890	protein-(glutamine-N5) methyltransferase activity
LXB15_01960	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LXB15_01965	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LXB15_01970	COG0527	aspartate kinase activity
LXB15_01975	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LXB15_01990	COG3795	YCII-related domain
LXB15_02000	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LXB15_02010	COG1040	competence protein
LXB15_02015	COG2226	methyltransferase
LXB15_02045	COG1376	ErfK ybiS ycfS ynhG family protein
LXB15_02060	COG0667	Aldo Keto reductase
LXB15_02065	COG0739	heme binding
LXB15_02110	COG3119	arylsulfatase activity
LXB15_02115	COG1653	transport
LXB15_02120	COG1175	transmembrane transport
LXB15_02125	COG0395	ABC-type sugar transport system, permease component
LXB15_02130	COG3842	ATPase activity
LXB15_02150	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
LXB15_02155	COG0477	Major facilitator Superfamily
LXB15_02160	COG2326	polyphosphate kinase activity
LXB15_02185	COG0183	Belongs to the thiolase family
LXB15_02195	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LXB15_02200	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LXB15_02205	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LXB15_02210	COG2721	sulfolactate sulfo-lyase activity
LXB15_02220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LXB15_02225	COG1312	Catalyzes the dehydration of D-mannonate
LXB15_02230	COG1802	Transcriptional regulator
LXB15_02235	COG1904	glucuronate isomerase
LXB15_02240	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LXB15_02255	COG0246	Mannitol dehydrogenase
LXB15_02270	COG1028	Short-chain dehydrogenase reductase Sdr
LXB15_02275	COG3386	PFAM SMP-30 Gluconolaconase
LXB15_02280	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
LXB15_02295	COG3833	ABC-type maltose transport systems, permease component
LXB15_02305	COG3842	ATPase activity
LXB15_02315	COG1686	Belongs to the peptidase S11 family
LXB15_02340	COG3622	Belongs to the hyi family
LXB15_02345	COG0708	Exodeoxyribonuclease III
LXB15_02370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LXB15_02375	COG0697	spore germination
LXB15_02395	COG1063	alcohol dehydrogenase
LXB15_02400	COG3718	enzyme involved in inositol metabolism
LXB15_02410	COG3962	Belongs to the TPP enzyme family
LXB15_02415	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LXB15_02425	COG1172	Belongs to the binding-protein-dependent transport system permease family
LXB15_02430	COG1879	ABC-type sugar transport system periplasmic component
LXB15_02445	COG3622	Belongs to the hyi family
LXB15_02450	COG0673	inositol 2-dehydrogenase activity
LXB15_02455	COG2358	TRAP transporter, solute receptor (TAXI family
LXB15_02475	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LXB15_02480	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
LXB15_02485	COG2080	2 iron, 2 sulfur cluster binding
LXB15_02525	COG1136	(ABC) transporter
LXB15_02550	COG0071	Belongs to the small heat shock protein (HSP20) family
LXB15_02590	COG3300	MHYT domain
LXB15_02590	COG5001	Diguanylate cyclase
LXB15_02595	COG0640	Transcriptional regulator
LXB15_02620	COG1653	transport
LXB15_02625	COG1175	transmembrane transport
LXB15_02630	COG0395	ABC-type sugar transport system, permease component
LXB15_02635	COG3842	ATPase activity
LXB15_02645	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LXB15_02650	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LXB15_02655	COG0583	DNA-binding transcription factor activity
LXB15_02670	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
LXB15_02680	COG1858	cytochrome C peroxidase
LXB15_02700	COG1733	regulation of RNA biosynthetic process
LXB15_02740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LXB15_02745	COG0842	Transport permease protein
LXB15_02745	COG1129	ABC transporter
LXB15_02750	COG0842	Transport permease protein
LXB15_02760	COG0444	Belongs to the ABC transporter superfamily
LXB15_02765	COG4172	Belongs to the ABC transporter superfamily
LXB15_02785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LXB15_02795	COG1309	transcriptional regulator
LXB15_02820	COG4558	Periplasmic binding protein
LXB15_02825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LXB15_02830	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
LXB15_02835	COG3720	iron ion transport
LXB15_02840	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LXB15_02845	COG0604	alcohol dehydrogenase
LXB15_02865	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LXB15_02875	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LXB15_02900	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LXB15_02915	COG3386	PFAM SMP-30 Gluconolaconase
LXB15_02925	COG1129	ABC transporter
LXB15_02930	COG4213	ABC transporter substrate-binding protein
LXB15_02935	COG1172	Belongs to the binding-protein-dependent transport system permease family
LXB15_02940	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LXB15_02945	COG3958	Transketolase
LXB15_02950	COG3959	Transketolase, thiamine diphosphate binding domain
LXB15_02960	COG1028	Short-chain dehydrogenase reductase Sdr
LXB15_03025	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LXB15_03040	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LXB15_03050	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LXB15_03055	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LXB15_03060	COG1082	Xylose isomerase domain protein TIM barrel
LXB15_03060	COG3185	4-Hydroxyphenylpyruvate dioxygenase
LXB15_03105	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LXB15_03110	COG0477	Major facilitator Superfamily
LXB15_03135	COG0753	catalase activity
LXB15_03140	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LXB15_03140	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LXB15_03145	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
LXB15_03155	COG3685	Protein conserved in bacteria
LXB15_03160	COG0519	Catalyzes the synthesis of GMP from XMP
LXB15_03160	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LXB15_03175	COG2267	carboxylic ester hydrolase activity
LXB15_03195	COG0745	RESPONSE REGULATOR receiver
LXB15_03280	COG3788	relative of glutathione S-transferase, MAPEG superfamily
LXB15_03295	COG1160	GTP binding
LXB15_03305	COG0800	Aldolase
LXB15_03330	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LXB15_03340	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LXB15_03365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LXB15_03390	COG1295	ribonuclease BN
LXB15_03400	COG1024	Enoyl-CoA hydratase
LXB15_03400	COG1250	3-hydroxyacyl-CoA dehydrogenase
LXB15_03405	COG2199	diguanylate cyclase activity
LXB15_03405	COG2200	EAL domain
LXB15_03410	COG0183	Belongs to the thiolase family
LXB15_03415	COG1960	acyl-CoA dehydrogenase activity
LXB15_03420	COG0789	Transcriptional regulator
LXB15_03430	COG0730	response to heat
LXB15_03475	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LXB15_03480	COG1201	RNA secondary structure unwinding
LXB15_03525	COG2202	Pas domain
LXB15_03525	COG3920	Histidine kinase
LXB15_03535	COG0126	phosphoglycerate kinase activity
LXB15_03540	COG3263	regulation of cellular component size
LXB15_03600	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LXB15_03620	COG0523	cobalamin synthesis protein
LXB15_03630	COG3153	acetyltransferase
LXB15_03640	COG0583	DNA-binding transcription factor activity
LXB15_03645	COG1376	ErfK ybiS ycfS ynhG family protein
LXB15_03685	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LXB15_03690	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LXB15_03700	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LXB15_03715	COG2137	regulation of response to DNA damage stimulus
LXB15_03720	COG0693	protein deglycase activity
LXB15_03740	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LXB15_03755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LXB15_03765	COG0446	pyridine nucleotide-disulphide oxidoreductase
LXB15_03765	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LXB15_03775	COG0625	glutathione transferase activity
LXB15_03780	COG0431	NADPH-dependent FMN reductase
LXB15_03805	COG0747	negative chemotaxis
LXB15_03815	COG1830	Aldolase
LXB15_03840	COG0596	Alpha beta hydrolase
LXB15_03845	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LXB15_03870	COG1703	isobutyryl-CoA mutase activity
LXB15_03875	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LXB15_03880	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
LXB15_03885	COG0535	radical SAM domain protein
LXB15_03890	COG0535	radical SAM domain protein
LXB15_03900	COG5001	Diguanylate cyclase
LXB15_03900	COG3300	MHYT domain
LXB15_03905	COG0598	Magnesium transport protein CorA
LXB15_03915	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LXB15_03915	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LXB15_03920	COG3920	Histidine kinase
LXB15_03930	COG0433	COG0433 Predicted ATPase
LXB15_03950	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LXB15_03955	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LXB15_03960	COG3909	cytochrome
LXB15_03965	COG2010	Cytochrome c
LXB15_03975	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LXB15_03975	COG2111	Na H antiporter
LXB15_03980	COG2111	Na H antiporter
LXB15_03985	COG1006	Multisubunit Na H antiporter MnhC subunit
LXB15_03990	COG0651	ATP synthesis coupled electron transport
LXB15_03995	COG1863	multisubunit Na H antiporter MnhE subunit
LXB15_04000	COG2212	antiporter activity
LXB15_04005	COG1320	monovalent cation:proton antiporter activity
LXB15_04025	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LXB15_04035	COG0493	'glutamate synthase
LXB15_04045	COG5001	Diguanylate cyclase
LXB15_04045	COG3300	MHYT domain
LXB15_04055	COG1309	transcriptional regulator
LXB15_04060	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LXB15_04095	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LXB15_04100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LXB15_04110	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LXB15_04115	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LXB15_04130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LXB15_04145	COG1157	protein secretion by the type III secretion system
LXB15_04150	COG4786	Flagellar basal body rod
LXB15_04155	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LXB15_04170	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LXB15_04175	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LXB15_04180	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LXB15_04190	COG1815	bacterial-type flagellum-dependent cell motility
LXB15_04195	COG1558	bacterial-type flagellum-dependent cell motility
LXB15_04200	COG1677	Flagellar hook-basal body complex protein FliE
LXB15_04205	COG4786	Flagellar basal body rod
LXB15_04210	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
LXB15_04215	COG1706	bacterial-type flagellum-dependent cell motility
LXB15_04225	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
LXB15_04235	COG1338	Plays a role in the flagellum-specific transport system
LXB15_04250	COG0840	transmembrane signaling receptor activity
LXB15_04250	COG2972	Histidine kinase
LXB15_04265	COG0784	Response regulator, receiver
LXB15_04265	COG0835	chemotaxis
LXB15_04270	COG0643	Histidine kinase
LXB15_04270	COG2198	Histidine kinase
LXB15_04275	COG0835	chemotaxis
LXB15_04280	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LXB15_04285	COG2201	protein-glutamate methylesterase activity
LXB15_04290	COG0745	RESPONSE REGULATOR receiver
LXB15_04295	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
LXB15_04315	COG1360	Flagellar Motor Protein
LXB15_04355	COG5443	negative regulation of bacterial-type flagellum assembly
LXB15_04360	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
LXB15_04365	COG4794	Type iii secretion
LXB15_04370	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LXB15_04375	COG1684	flagellar biosynthetic protein fliR
LXB15_04415	COG0513	Belongs to the DEAD box helicase family
LXB15_04420	COG1686	Belongs to the peptidase S11 family
LXB15_04425	COG0488	(ABC) transporter
LXB15_04485	COG0784	Response regulator, receiver
LXB15_04520	COG0747	negative chemotaxis
LXB15_04525	COG0601	transmembrane transport
LXB15_04530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LXB15_04535	COG0444	Belongs to the ABC transporter superfamily
LXB15_04540	COG4608	Belongs to the ABC transporter superfamily
LXB15_04555	COG4175	Glycine betaine
LXB15_04580	COG2759	Belongs to the formate--tetrahydrofolate ligase family
LXB15_04585	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LXB15_04590	COG3842	ATPase activity
LXB15_04595	COG1178	ABC-type Fe3 transport system permease component
LXB15_04605	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
LXB15_04610	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LXB15_04610	COG0512	Glutamine amidotransferase of anthranilate synthase
LXB15_04615	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LXB15_04625	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LXB15_04635	COG0596	Alpha beta hydrolase
LXB15_04635	COG0508	dehydrogenase complex catalyzes the overall conversion of
LXB15_04650	COG0494	nUDIX hydrolase
LXB15_04655	COG0435	Glutathione S-transferase
LXB15_04680	COG0714	Associated with various cellular activities
LXB15_04690	COG0494	nUDIX hydrolase
LXB15_04695	COG0617	tRNA 3'-terminal CCA addition
LXB15_04705	COG0408	coproporphyrinogen oxidase activity
LXB15_04720	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LXB15_04725	COG1132	(ABC) transporter
LXB15_04730	COG1132	(ABC) transporter
LXB15_04745	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LXB15_04745	COG2857	Cytochrome c1
LXB15_04755	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LXB15_04760	COG0778	Nitroreductase
LXB15_04770	COG2030	dehydratase
LXB15_04775	COG0012	GTP binding
LXB15_04780	COG0193	aminoacyl-tRNA hydrolase activity
LXB15_04785	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LXB15_04815	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LXB15_04835	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LXB15_04845	COG0745	RESPONSE REGULATOR receiver
LXB15_04850	COG1846	Transcriptional regulator
LXB15_04865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LXB15_04875	COG1278	Cold shock
LXB15_04925	COG0556	nucleotide-excision repair
LXB15_04960	COG1959	2 iron, 2 sulfur cluster binding
LXB15_04965	COG2267	carboxylic ester hydrolase activity
LXB15_05000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LXB15_05005	COG0765	amino acid transport
LXB15_05010	COG1126	abc transporter atp-binding protein
LXB15_05025	COG0583	DNA-binding transcription factor activity
LXB15_05035	COG2116	formate transmembrane transporter activity
LXB15_05040	COG2226	methyltransferase
LXB15_05055	COG2032	superoxide dismutase activity
LXB15_05065	COG0436	Aminotransferase
LXB15_05080	COG1285	pathogenesis
LXB15_05085	COG2267	carboxylic ester hydrolase activity
LXB15_05105	COG0625	glutathione transferase activity
LXB15_05125	COG0784	Response regulator, receiver
LXB15_05135	COG0586	Pfam SNARE associated Golgi protein
LXB15_05150	COG1720	tRNA m6t6A37 methyltransferase activity
LXB15_05155	COG0640	Transcriptional regulator
LXB15_05210	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
LXB15_05215	COG3023	N-Acetylmuramoyl-L-alanine amidase
LXB15_05230	COG2001	Belongs to the MraZ family
LXB15_05235	COG0275	rRNA processing
LXB15_05250	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LXB15_05265	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LXB15_05275	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LXB15_05280	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LXB15_05290	COG1181	Belongs to the D-alanine--D-alanine ligase family
LXB15_05295	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LXB15_05300	COG0849	cell division
LXB15_05305	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LXB15_05315	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LXB15_05330	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LXB15_05345	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LXB15_05350	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
LXB15_05415	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LXB15_05415	COG3153	acetyltransferase
LXB15_05445	COG1122	ATPase activity
LXB15_05450	COG1268	BioY protein
LXB15_05465	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LXB15_05480	COG0395	ABC-type sugar transport system, permease component
LXB15_05490	COG3842	ATPase activity
LXB15_05495	COG3842	ATPase activity
LXB15_05555	COG0671	phosphoesterase, PA-phosphatase related
LXB15_05560	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LXB15_05570	COG1176	ABC-type spermidine putrescine transport system, permease component I
LXB15_05575	COG3842	ATPase activity
LXB15_05590	COG0436	Aminotransferase
LXB15_05595	COG0583	DNA-binding transcription factor activity
LXB15_05600	COG0840	transmembrane signaling receptor activity
LXB15_05610	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LXB15_05620	COG0500	methyltransferase
LXB15_05625	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LXB15_05640	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
LXB15_05645	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LXB15_05675	COG0395	ABC-type sugar transport system, permease component
LXB15_05680	COG1175	transmembrane transport
LXB15_05685	COG1653	transport
LXB15_05690	COG1609	Transcriptional regulator
LXB15_05705	COG3383	formate dehydrogenase (NAD+) activity
LXB15_05735	COG1215	transferase activity, transferring glycosyl groups
LXB15_05765	COG1126	abc transporter atp-binding protein
LXB15_05775	COG0765	amino acid transport
LXB15_05780	COG0765	amino acid transport
LXB15_05785	COG0640	Transcriptional regulator
LXB15_05795	COG0785	Cytochrome C biogenesis protein
LXB15_05830	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LXB15_05855	COG0346	lactoylglutathione lyase activity
LXB15_05895	COG0714	Associated with various cellular activities
LXB15_05915	COG2864	formate dehydrogenase
LXB15_05920	COG0437	4 iron, 4 sulfur cluster binding
LXB15_05925	COG0243	molybdopterin cofactor binding
LXB15_05925	COG3383	formate dehydrogenase (NAD+) activity
LXB15_05975	COG0425	Belongs to the sulfur carrier protein TusA family
LXB15_05980	COG0303	'Molybdopterin
LXB15_05985	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LXB15_05990	COG0746	molybdenum cofactor guanylyltransferase activity
LXB15_05995	COG0303	'Molybdopterin
LXB15_06025	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LXB15_06030	COG0318	PFAM AMP-dependent synthetase and ligase
LXB15_06035	COG0179	Fumarylacetoacetate (FAA) hydrolase
LXB15_06040	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LXB15_06050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LXB15_06060	COG2186	Transcriptional regulator
LXB15_06075	COG1024	Enoyl-CoA hydratase
LXB15_06105	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LXB15_06115	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LXB15_06135	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LXB15_06140	COG0730	response to heat
LXB15_06145	COG3577	Aspartyl protease
LXB15_06155	COG2202	Pas domain
LXB15_06155	COG2205	protein histidine kinase activity
LXB15_06160	COG0625	glutathione transferase activity
LXB15_06165	COG1573	uracil-dna glycosylase
LXB15_06170	COG1522	sequence-specific DNA binding
LXB15_06175	COG2084	Dehydrogenase
LXB15_06200	COG2814	Major facilitator Superfamily
LXB15_06215	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LXB15_06240	COG2308	Evidence 4 Homologs of previously reported genes of
LXB15_06245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LXB15_06250	COG0644	oxidoreductase
LXB15_06255	COG2211	Major facilitator Superfamily
LXB15_06260	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LXB15_06280	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
LXB15_06285	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
LXB15_06290	COG1429	ligase activity, forming nitrogen-metal bonds
LXB15_06295	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
LXB15_06330	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
LXB15_06335	COG0523	cobalamin synthesis protein
LXB15_06370	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
LXB15_06375	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
LXB15_06380	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
LXB15_06385	COG1063	alcohol dehydrogenase
LXB15_06390	COG0500	methyltransferase
LXB15_06405	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
LXB15_06415	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
LXB15_06440	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LXB15_06450	COG1032	radical SAM domain protein
LXB15_06495	COG0318	PFAM AMP-dependent synthetase and ligase
LXB15_06515	COG0367	asparagine synthase
LXB15_06570	COG2010	Cytochrome c
LXB15_06625	COG1228	amidohydrolase
LXB15_06630	COG2986	histidine ammonia-lyase
LXB15_06640	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LXB15_06645	COG1280	lysine exporter protein (LysE YggA)
LXB15_06675	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LXB15_06680	COG1295	ribonuclease BN
LXB15_06680	COG1959	2 iron, 2 sulfur cluster binding
LXB15_06740	COG2124	cytochrome p450
LXB15_06785	COG1615	UPF0182 protein
LXB15_06810	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LXB15_06945	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
LXB15_06950	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LXB15_06990	COG1253	flavin adenine dinucleotide binding
LXB15_07025	COG3909	cytochrome
LXB15_07120	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LXB15_07125	COG0363	glucosamine-6-phosphate deaminase activity
LXB15_07135	COG3842	ATPase activity
LXB15_07140	COG1177	transmembrane transport
LXB15_07150	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LXB15_07155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LXB15_07160	COG1397	ADP-ribosylglycohydrolase
LXB15_07165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LXB15_07170	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LXB15_07180	COG1335	isochorismatase
LXB15_07185	COG2309	aminopeptidase activity
LXB15_07190	COG0596	Alpha beta hydrolase
LXB15_07195	COG3473	Maleate cis-trans isomerase
LXB15_07200	COG1846	Transcriptional regulator
LXB15_07205	COG2080	2 iron, 2 sulfur cluster binding
LXB15_07210	COG2010	Cytochrome c
LXB15_07210	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LXB15_07215	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LXB15_07225	COG1335	isochorismatase
LXB15_07275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LXB15_07305	COG0154	amidase activity
LXB15_07350	COG4948	Mandelate Racemase Muconate Lactonizing
LXB15_07365	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LXB15_07385	COG2207	Transcriptional regulator
LXB15_07395	COG1335	isochorismatase
LXB15_07410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LXB15_07425	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LXB15_07450	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LXB15_07450	COG1017	nitric oxide dioxygenase activity
LXB15_07455	COG0625	glutathione transferase activity
LXB15_07460	COG0583	DNA-binding transcription factor activity
LXB15_07465	COG1309	transcriptional regulator
LXB15_07470	COG1028	Short-chain dehydrogenase reductase Sdr
LXB15_07485	COG5507	3-demethylubiquinone-9 3-methyltransferase
LXB15_07570	COG0546	phosphoglycolate phosphatase activity
LXB15_07575	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LXB15_07600	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
LXB15_07605	COG3384	dioxygenase
LXB15_07635	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LXB15_07635	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
LXB15_07640	COG0280	phosphate acetyltransferase
LXB15_07640	COG0281	malic enzyme
LXB15_07650	COG0438	transferase activity, transferring glycosyl groups
LXB15_07655	COG4948	Mandelate Racemase Muconate Lactonizing
LXB15_07660	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LXB15_07665	COG1127	ABC transporter
LXB15_07675	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LXB15_07675	COG3218	ABC-type transport auxiliary lipoprotein component
LXB15_07690	COG0633	Ferredoxin
LXB15_07700	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LXB15_07705	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LXB15_07715	COG3768	UPF0283 membrane protein
LXB15_07720	COG3106	COG3106 Predicted ATPase
LXB15_07745	COG2313	pseudouridylate synthase activity
LXB15_07760	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LXB15_07770	COG0538	isocitrate dehydrogenase activity
LXB15_07775	COG2272	Belongs to the type-B carboxylesterase lipase family
LXB15_07785	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LXB15_07810	COG0037	tRNA processing
LXB15_07815	COG0483	inositol monophosphate 1-phosphatase activity
LXB15_07835	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LXB15_07855	COG0047	phosphoribosylformylglycinamidine synthase activity
LXB15_07865	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LXB15_07870	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LXB15_07895	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LXB15_07905	COG3191	aminopeptidase activity
LXB15_07910	COG0683	leucine binding
LXB15_07915	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LXB15_07935	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LXB15_07935	COG3608	succinylglutamate desuccinylase aspartoacylase
LXB15_07940	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LXB15_07955	COG5425	PFAM Usg family protein
LXB15_07965	COG2003	Belongs to the UPF0758 family
LXB15_07970	COG0024	Methionine aminopeptidase
LXB15_07975	COG3243	poly(R)-hydroxyalkanoic acid synthase
LXB15_07985	COG0436	Aminotransferase
LXB15_08000	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LXB15_08010	COG3750	Belongs to the UPF0335 family
LXB15_08025	COG1960	acyl-CoA dehydrogenase activity
LXB15_08035	COG0411	ABC transporter
LXB15_08055	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LXB15_08070	COG0525	valine-tRNA ligase activity
LXB15_08080	COG0129	dihydroxy-acid dehydratase activity
LXB15_08085	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
LXB15_08095	COG0316	Belongs to the HesB IscA family
LXB15_08100	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LXB15_08105	COG0018	arginyl-trna synthetase
LXB15_08115	COG1472	Belongs to the glycosyl hydrolase 3 family
LXB15_08120	COG3842	ATPase activity
LXB15_08125	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LXB15_08130	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LXB15_08135	COG0805	protein transport
LXB15_08150	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LXB15_08165	COG1862	Preprotein translocase
LXB15_08175	COG3737	Protein of unknown function (DUF498/DUF598)
LXB15_08190	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LXB15_08205	COG0544	peptidyl-prolyl cis-trans isomerase activity
LXB15_08210	COG0668	transmembrane transport
LXB15_08215	COG0740	serine-type endopeptidase activity
LXB15_08220	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LXB15_08230	COG0776	regulation of translation
LXB15_08250	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LXB15_08255	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LXB15_08260	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LXB15_08270	COG0649	NAD binding
LXB15_08275	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
LXB15_08280	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LXB15_08290	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LXB15_08300	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LXB15_08310	COG0713	ATP synthesis coupled electron transport
LXB15_08325	COG1007	ATP synthesis coupled electron transport
LXB15_08340	COG0346	lactoylglutathione lyase activity
LXB15_08350	COG0442	prolyl-tRNA aminoacylation
LXB15_08370	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LXB15_08385	COG0784	Response regulator, receiver
LXB15_08395	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LXB15_08415	COG0557	exoribonuclease II activity
LXB15_08420	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LXB15_08420	COG1754	DNA topoisomerase type I activity
LXB15_08430	COG0758	DNA mediated transformation
LXB15_08435	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LXB15_08440	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LXB15_08450	COG1960	acyl-CoA dehydrogenase activity
LXB15_08465	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LXB15_08470	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LXB15_08475	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LXB15_08505	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LXB15_08520	COG4765	Protein conserved in bacteria
LXB15_08525	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
LXB15_08540	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LXB15_08555	COG0436	Aminotransferase
LXB15_08560	COG1530	ribonuclease E activity
LXB15_08565	COG0860	N-Acetylmuramoyl-L-alanine amidase
LXB15_08570	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LXB15_08580	COG0739	heme binding
LXB15_08585	COG2833	Protein of unknown function (DUF455)
LXB15_08590	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LXB15_08600	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LXB15_08605	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LXB15_08610	COG2945	thiolester hydrolase activity
LXB15_08615	COG1104	cysteine desulfurase activity
LXB15_08620	COG0719	Fe-S assembly protein
LXB15_08630	COG0396	ATPase activity
LXB15_08635	COG0719	Fe-S assembly protein
LXB15_08640	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LXB15_08645	COG2151	metal-sulfur cluster biosynthetic enzyme
LXB15_08655	COG0316	Belongs to the HesB IscA family
LXB15_08665	COG3956	TIGRFAM MazG family protein
LXB15_08670	COG0321	lipoyl(octanoyl) transferase activity
LXB15_08670	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LXB15_08675	COG0084	hydrolase, TatD family'
LXB15_08680	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LXB15_08685	COG0470	DNA polymerase III
LXB15_08695	COG1686	Belongs to the peptidase S11 family
LXB15_08715	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LXB15_08725	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LXB15_08730	COG2942	2-epimerase
LXB15_08735	COG1802	Transcriptional regulator
LXB15_08740	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LXB15_08745	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LXB15_08765	COG1183	phosphatidylcholine synthase activity
LXB15_08775	COG0679	Auxin Efflux Carrier
LXB15_08790	COG4166	transmembrane transport
LXB15_08800	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LXB15_08810	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LXB15_08820	COG0785	Cytochrome C biogenesis protein
LXB15_08845	COG0343	queuine tRNA-ribosyltransferase activity
LXB15_08850	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LXB15_08865	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LXB15_08870	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LXB15_08875	COG2095	MarC family integral membrane protein
LXB15_08890	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LXB15_08915	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LXB15_08915	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LXB15_08920	COG0347	Belongs to the P(II) protein family
LXB15_08925	COG0174	glutamine synthetase
LXB15_08930	COG0187	DNA topoisomerase II activity
LXB15_08940	COG2267	carboxylic ester hydrolase activity
LXB15_08945	COG0513	Belongs to the DEAD box helicase family
LXB15_08950	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LXB15_08960	COG0569	domain protein
LXB15_08965	COG2204	response regulator
LXB15_08970	COG5000	phosphorelay sensor kinase activity
LXB15_08975	COG2204	response regulator
LXB15_08980	COG3852	Histidine kinase
LXB15_08995	COG1058	Belongs to the CinA family
LXB15_08995	COG1546	Belongs to the CinA family
LXB15_09000	COG2867	negative regulation of translational initiation
LXB15_09005	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LXB15_09015	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LXB15_09030	COG0508	dehydrogenase complex catalyzes the overall conversion of
LXB15_09040	COG0022	dehydrogenase e1 component
LXB15_09040	COG0508	dehydrogenase complex catalyzes the overall conversion of
LXB15_09045	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LXB15_09050	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LXB15_09055	COG0148	phosphopyruvate hydratase activity
LXB15_09070	COG0504	CTP synthase activity
LXB15_09080	COG0149	triose-phosphate isomerase activity
LXB15_09090	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LXB15_09095	COG0134	indole-3-glycerol-phosphate synthase activity
LXB15_09100	COG0315	cyclic pyranopterin monophosphate synthase activity
LXB15_09105	COG0303	'Molybdopterin
LXB15_09115	COG2333	competence protein COMEC
LXB15_09115	COG0658	competence protein
LXB15_09125	COG0372	Belongs to the citrate synthase family
LXB15_09130	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LXB15_09140	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LXB15_09145	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LXB15_09150	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LXB15_09160	COG0750	zinc metalloprotease
LXB15_09170	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LXB15_09175	COG0233	cytoplasmic translational termination
LXB15_09180	COG0528	UMP kinase activity
LXB15_09185	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LXB15_09190	COG0052	Belongs to the universal ribosomal protein uS2 family
LXB15_09215	COG0537	adenosine 5'-monophosphoramidase activity
LXB15_09235	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LXB15_09265	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LXB15_09270	COG0656	L-ascorbic acid biosynthetic process
LXB15_09285	COG2239	Acts as a magnesium transporter
LXB15_09295	COG1597	lipid kinase activity
LXB15_09315	COG0321	lipoyl(octanoyl) transferase activity
LXB15_09320	COG4770	biotin carboxylase activity
LXB15_09335	COG1671	Belongs to the UPF0178 family
LXB15_09340	COG3706	GGDEF domain
LXB15_09340	COG5001	Diguanylate cyclase
LXB15_09340	COG4251	negative regulation of phosphorylation
LXB15_09340	COG2203	Gaf domain
LXB15_09345	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LXB15_09365	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LXB15_09370	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LXB15_09375	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LXB15_09385	COG0203	ribosomal protein L17
LXB15_09395	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LXB15_09400	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LXB15_09405	COG0563	adenylate kinase activity
LXB15_09415	COG0200	Binds to the 23S rRNA
LXB15_09420	COG1841	ribosomal large subunit assembly
LXB15_09425	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LXB15_09430	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LXB15_09440	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LXB15_09445	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LXB15_09450	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LXB15_09455	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LXB15_09460	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LXB15_09465	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LXB15_09470	COG0255	Belongs to the universal ribosomal protein uL29 family
LXB15_09475	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LXB15_09480	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LXB15_09490	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LXB15_09500	COG0089	rRNA binding
LXB15_09505	COG0088	Forms part of the polypeptide exit tunnel
LXB15_09520	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LXB15_09525	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LXB15_09530	COG0049	tRNA binding
LXB15_09535	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LXB15_09545	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LXB15_09550	COG0085	RNA polymerase activity
LXB15_09555	COG0222	ribosome binding
LXB15_09560	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LXB15_09565	COG0081	regulation of translation
LXB15_09580	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LXB15_09590	COG0546	phosphoglycolate phosphatase activity
LXB15_09625	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LXB15_09640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LXB15_09650	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LXB15_09680	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LXB15_09690	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LXB15_09700	COG0302	gtp cyclohydrolase
LXB15_09705	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LXB15_09710	COG1752	Esterase of the alpha-beta hydrolase superfamily
LXB15_09715	COG0517	IMP dehydrogenase activity
LXB15_09715	COG0516	GMP reductase activity
LXB15_09765	COG0628	permease
LXB15_09770	COG1126	abc transporter atp-binding protein
LXB15_09775	COG0765	amino acid transport
LXB15_09780	COG4597	amino acid ABC transporter
LXB15_09785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LXB15_09790	COG0626	cystathionine gamma-synthase activity
LXB15_09795	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LXB15_09825	COG0346	lactoylglutathione lyase activity
LXB15_09855	COG1450	Type ii and iii secretion system protein
LXB15_09860	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LXB15_09905	COG1459	type II secretion system
LXB15_09915	COG2132	Multicopper oxidase
LXB15_09925	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LXB15_09945	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
LXB15_09955	COG4585	Histidine kinase
LXB15_10015	COG0415	Belongs to the DNA photolyase family
LXB15_10035	COG4106	trans-aconitate 2-methyltransferase activity
LXB15_10055	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LXB15_10060	COG2897	thiosulfate sulfurtransferase activity
LXB15_10070	COG2423	ornithine cyclodeaminase activity
LXB15_10085	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LXB15_10090	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LXB15_10105	COG0655	NAD(P)H dehydrogenase (quinone) activity
LXB15_10110	COG1546	Belongs to the CinA family
LXB15_10110	COG1058	Belongs to the CinA family
LXB15_10120	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
LXB15_10125	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LXB15_10150	COG1376	ErfK ybiS ycfS ynhG family protein
LXB15_10155	COG1376	ErfK ybiS ycfS ynhG family protein
LXB15_10155	COG1388	LysM domain
LXB15_10200	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LXB15_10205	COG1335	isochorismatase
LXB15_10235	COG1802	Transcriptional regulator
LXB15_10260	COG0318	PFAM AMP-dependent synthetase and ligase
LXB15_10265	COG5001	Diguanylate cyclase
LXB15_10270	COG0784	Response regulator, receiver
LXB15_10280	COG4176	ABC-type proline glycine betaine transport system permease component
LXB15_10285	COG3448	diguanylate cyclase activity
LXB15_10285	COG4175	Glycine betaine
LXB15_10295	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LXB15_10295	COG0646	methionine synthase
LXB15_10300	COG3300	MHYT domain
LXB15_10300	COG5001	Diguanylate cyclase
LXB15_10305	COG1115	amino acid carrier protein
LXB15_10325	COG5012	cobalamin binding
LXB15_10350	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LXB15_10405	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LXB15_10415	COG0277	FAD linked oxidase domain protein
LXB15_10420	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LXB15_10420	COG0546	phosphoglycolate phosphatase activity
LXB15_10425	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LXB15_10430	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LXB15_10445	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LXB15_10450	COG0492	ferredoxin-NADP+ reductase activity
LXB15_10455	COG0583	DNA-binding transcription factor activity
LXB15_10505	COG3706	GGDEF domain
LXB15_10510	COG1832	CoA-binding protein
LXB15_10525	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LXB15_10530	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LXB15_10540	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LXB15_10545	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LXB15_10550	COG0010	Belongs to the arginase family
LXB15_10560	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LXB15_10565	COG1612	heme a metabolic process
LXB15_10580	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LXB15_10600	COG1596	polysaccharide export
LXB15_10605	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LXB15_10625	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LXB15_10640	COG0776	regulation of translation
LXB15_10650	COG0416	fatty acid biosynthetic process
LXB15_10670	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
LXB15_10675	COG2814	Major facilitator Superfamily
LXB15_10680	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LXB15_10695	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LXB15_10695	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LXB15_10700	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LXB15_10705	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LXB15_10725	COG0113	porphobilinogen synthase activity
LXB15_10735	COG3273	potassium ion transport
LXB15_10735	COG0471	metal ion transport
LXB15_10740	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
LXB15_10745	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LXB15_10760	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LXB15_10765	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
LXB15_10775	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LXB15_10785	COG0628	permease
LXB15_10795	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LXB15_10800	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LXB15_10810	COG0243	molybdopterin cofactor binding
LXB15_10815	COG1902	pentaerythritol trinitrate reductase activity
LXB15_10820	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LXB15_10845	COG0322	excinuclease ABC activity
LXB15_10860	COG0314	molybdopterin synthase activity
LXB15_10870	COG0105	UTP biosynthetic process
LXB15_10885	COG0488	(ABC) transporter
LXB15_10900	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LXB15_10925	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LXB15_10930	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LXB15_10935	COG0194	GDP metabolic process
LXB15_10940	COG1561	YicC-like family, N-terminal region
LXB15_10945	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LXB15_10950	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LXB15_10965	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LXB15_10970	COG0360	Binds together with S18 to 16S ribosomal RNA
LXB15_10975	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LXB15_10990	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LXB15_11000	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LXB15_11020	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LXB15_11025	COG4221	oxidoreductase activity
LXB15_11030	COG1183	phosphatidylcholine synthase activity
LXB15_11035	COG0688	phosphatidylethanolamine metabolic process
LXB15_11040	COG5265	(ABC) transporter
LXB15_11075	COG1401	restriction endodeoxyribonuclease activity
LXB15_11135	COG3227	Zinc metalloprotease (Elastase)
LXB15_11150	COG0583	DNA-binding transcription factor activity
LXB15_11160	COG0601	transmembrane transport
LXB15_11165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LXB15_11170	COG0444	Belongs to the ABC transporter superfamily
LXB15_11175	COG4608	Belongs to the ABC transporter superfamily
LXB15_11180	COG1473	amidohydrolase
LXB15_11195	COG4172	Belongs to the ABC transporter superfamily
LXB15_11205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LXB15_11215	COG0747	negative chemotaxis
LXB15_11225	COG0583	DNA-binding transcription factor activity
LXB15_11255	COG0583	DNA-binding transcription factor activity
LXB15_11260	COG0402	S-adenosylhomocysteine deaminase activity
LXB15_11265	COG0583	DNA-binding transcription factor activity
LXB15_11285	COG3842	ATPase activity
LXB15_11290	COG0402	S-adenosylhomocysteine deaminase activity
LXB15_11320	COG1794	racemase activity, acting on amino acids and derivatives
LXB15_11325	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LXB15_11330	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
LXB15_11345	COG0300	oxidoreductase activity
LXB15_11365	COG0583	DNA-binding transcription factor activity
LXB15_11370	COG2084	Dehydrogenase
LXB15_11375	COG0300	oxidoreductase activity
LXB15_11405	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LXB15_11410	COG1595	DNA-templated transcription, initiation
LXB15_11450	COG1335	isochorismatase
LXB15_11455	COG4566	intracellular signal transduction
LXB15_11460	COG4191	Histidine kinase
LXB15_11470	COG1335	isochorismatase
LXB15_11475	COG0583	DNA-binding transcription factor activity
LXB15_11480	COG1741	Belongs to the pirin family
LXB15_11520	COG0460	homoserine dehydrogenase
LXB15_11525	COG0505	Belongs to the CarA family
LXB15_11530	COG1505	serine-type exopeptidase activity
LXB15_11555	COG0583	DNA-binding transcription factor activity
LXB15_11560	COG1376	ErfK ybiS ycfS ynhG family protein
LXB15_11565	COG0475	glutathione-regulated potassium exporter activity
LXB15_11565	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LXB15_11595	COG1959	2 iron, 2 sulfur cluster binding
LXB15_11600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LXB15_11610	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
LXB15_11620	COG0471	metal ion transport
LXB15_11620	COG3273	potassium ion transport
LXB15_11625	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LXB15_11630	COG4208	sulfate ABC transporter
LXB15_11640	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LXB15_11645	COG1959	2 iron, 2 sulfur cluster binding
LXB15_11680	COG1366	Belongs to the anti-sigma-factor antagonist family
LXB15_11685	COG2172	sigma factor antagonist activity
LXB15_11720	COG3920	Histidine kinase
LXB15_11735	COG2968	Membrane
LXB15_11745	COG1028	Short-chain dehydrogenase reductase Sdr
LXB15_11755	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LXB15_11760	COG0358	DNA primase activity
LXB15_11770	COG1346	cytolysis
LXB15_11780	COG0505	Belongs to the CarA family
LXB15_11810	COG1802	Transcriptional regulator
LXB15_11815	COG0247	lactate metabolic process
LXB15_11815	COG0277	FAD linked oxidase domain protein
LXB15_11820	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LXB15_11825	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LXB15_11835	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LXB15_11835	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LXB15_11840	COG1024	Enoyl-CoA hydratase
LXB15_11855	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LXB15_11860	COG0509	glycine decarboxylation via glycine cleavage system
LXB15_11865	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LXB15_11865	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LXB15_11885	COG0747	negative chemotaxis
LXB15_11890	COG0601	transmembrane transport
LXB15_11895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LXB15_11910	COG1473	amidohydrolase
LXB15_11920	COG0154	amidase activity
LXB15_11945	COG0730	response to heat
LXB15_11960	COG0514	ATP-dependent DNA helicase (RecQ)
LXB15_12040	COG4964	Belongs to the GSP D family
LXB15_12055	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LXB15_12060	COG0456	acetyltransferase
LXB15_12075	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LXB15_12080	COG1309	transcriptional regulator
LXB15_12090	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LXB15_12100	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LXB15_12105	COG0784	Response regulator, receiver
LXB15_12105	COG4191	Histidine kinase
LXB15_12115	COG0440	acetolactate synthase activity
LXB15_12120	COG0028	Belongs to the TPP enzyme family
LXB15_12135	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LXB15_12140	COG0560	Phosphoserine phosphatase
LXB15_12140	COG3830	Belongs to the UPF0237 family
LXB15_12155	COG0330	HflC and HflK could
LXB15_12160	COG0330	HflC and HflK could
LXB15_12170	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LXB15_12200	COG0277	FAD linked oxidase domain protein
LXB15_12210	COG5001	Diguanylate cyclase
LXB15_12210	COG3300	MHYT domain
LXB15_12230	COG5001	Diguanylate cyclase
LXB15_12240	COG0753	catalase activity
LXB15_12255	COG0412	Dienelactone hydrolase
LXB15_12260	COG0210	DNA helicase
LXB15_12265	COG2852	Protein conserved in bacteria
LXB15_12290	COG2264	protein methyltransferase activity
LXB15_12300	COG1999	signal sequence binding
LXB15_12310	COG2814	Major facilitator Superfamily
LXB15_12320	COG0456	acetyltransferase
LXB15_12330	COG0215	cysteine-tRNA ligase activity
LXB15_12340	COG2135	peptidase activity
LXB15_12370	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LXB15_12375	COG0354	folic acid binding
LXB15_12380	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
LXB15_12405	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LXB15_12410	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LXB15_12420	COG1381	Involved in DNA repair and RecF pathway recombination
LXB15_12425	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LXB15_12435	COG0681	Belongs to the peptidase S26 family
LXB15_12450	COG1758	RNA polymerase activity
LXB15_12460	COG1573	uracil-dna glycosylase
LXB15_12470	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LXB15_12480	COG0741	lytic transglycosylase activity
LXB15_12485	COG3743	rRNA binding
LXB15_12485	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LXB15_12500	COG0420	3'-5' exonuclease activity
LXB15_12505	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LXB15_12525	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LXB15_12540	COG1028	Short-chain dehydrogenase reductase Sdr
LXB15_12545	COG1309	transcriptional regulator
LXB15_12560	COG0625	glutathione transferase activity
LXB15_12570	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LXB15_12580	COG1280	lysine exporter protein (LysE YggA)
LXB15_12585	COG2816	NAD+ diphosphatase activity
LXB15_12595	COG2378	regulation of single-species biofilm formation
LXB15_12645	COG1573	uracil-dna glycosylase
LXB15_12690	COG2197	response regulator
LXB15_12700	COG0697	spore germination
LXB15_12710	COG0308	aminopeptidase N
LXB15_12715	COG2205	protein histidine kinase activity
LXB15_12715	COG2202	Pas domain
LXB15_12720	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LXB15_12725	COG2205	protein histidine kinase activity
LXB15_12730	COG0745	RESPONSE REGULATOR receiver
LXB15_12735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LXB15_12740	COG3088	subunit of a heme lyase
LXB15_12745	COG1138	Cytochrome C-type biogenesis protein
LXB15_12870	COG4695	Portal protein
LXB15_12895	COG2983	Belongs to the UPF0260 family
LXB15_12900	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LXB15_12935	COG2205	protein histidine kinase activity
LXB15_12945	COG2166	iron-sulfur cluster assembly
LXB15_12955	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LXB15_12990	COG4565	transcriptional regulatory protein
LXB15_13000	COG5002	protein histidine kinase activity
LXB15_13005	COG1063	alcohol dehydrogenase
LXB15_13010	COG0583	DNA-binding transcription factor activity
LXB15_13015	COG4953	penicillin-binding protein 1C
LXB15_13020	COG2373	Large extracellular alpha-helical protein
LXB15_13030	COG0346	lactoylglutathione lyase activity
LXB15_13035	COG1072	(Pantothenic acid kinase))
LXB15_13040	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LXB15_13045	COG2194	sulfuric ester hydrolase activity
LXB15_13055	COG0642	Histidine kinase
LXB15_13065	COG1012	belongs to the aldehyde dehydrogenase family
LXB15_13070	COG0129	dihydroxy-acid dehydratase activity
LXB15_13105	COG1028	Short-chain dehydrogenase reductase Sdr
LXB15_13110	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LXB15_13120	COG0667	Aldo Keto reductase
LXB15_13125	COG1309	transcriptional regulator
LXB15_13145	COG3395	kinase activity
LXB15_13150	COG0235	Class ii aldolase
LXB15_13155	COG3622	Belongs to the hyi family
LXB15_13165	COG0745	RESPONSE REGULATOR receiver
LXB15_13170	COG0642	Histidine kinase
LXB15_13180	COG2223	nitrite transmembrane transporter activity
LXB15_13200	COG1280	lysine exporter protein (LysE YggA)
LXB15_13210	COG3920	Histidine kinase
LXB15_13215	COG1733	regulation of RNA biosynthetic process
LXB15_13220	COG1028	Short-chain dehydrogenase reductase Sdr
LXB15_13230	COG1733	regulation of RNA biosynthetic process
LXB15_13240	COG3239	Fatty acid desaturase
LXB15_13265	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LXB15_13285	COG4214	carbohydrate transport
LXB15_13295	COG0850	regulation of cytokinetic process
LXB15_13300	COG2894	cell division
LXB15_13305	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
LXB15_13375	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LXB15_13460	COG4115	mRNA cleavage
LXB15_13495	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LXB15_13530	COG0667	Aldo Keto reductase
LXB15_13535	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LXB15_13540	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LXB15_13565	COG4172	Belongs to the ABC transporter superfamily
LXB15_13580	COG0601	transmembrane transport
LXB15_13585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LXB15_13610	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LXB15_13630	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LXB15_13665	COG1063	alcohol dehydrogenase
LXB15_13670	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LXB15_13680	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LXB15_13705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LXB15_13720	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LXB15_13730	COG0482	sulfurtransferase activity
LXB15_13745	COG0745	RESPONSE REGULATOR receiver
LXB15_13770	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LXB15_13780	COG5001	Diguanylate cyclase
LXB15_13800	COG0564	pseudouridine synthase activity
LXB15_13805	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LXB15_13815	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LXB15_13825	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LXB15_13850	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LXB15_13855	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LXB15_13860	COG0037	tRNA processing
LXB15_13870	COG2885	chlorophyll binding
LXB15_13895	COG0824	Thioesterase
LXB15_13920	COG2255	four-way junction helicase activity
LXB15_13925	COG0632	four-way junction helicase activity
LXB15_13930	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LXB15_13940	COG0217	transcriptional regulatory protein
LXB15_13960	COG1253	flavin adenine dinucleotide binding
LXB15_13965	COG1692	metallophosphoesterase
LXB15_13985	COG0717	Belongs to the dCTP deaminase family
LXB15_13995	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LXB15_14000	COG2967	ApaG domain
LXB15_14010	COG3609	addiction module antidote protein, CC2985 family
LXB15_14025	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LXB15_14030	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LXB15_14040	COG0745	RESPONSE REGULATOR receiver
LXB15_14045	COG0704	Plays a role in the regulation of phosphate uptake
LXB15_14050	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LXB15_14060	COG0573	inorganic phosphate transmembrane transporter activity
LXB15_14070	COG5002	protein histidine kinase activity
LXB15_14085	COG1028	Short-chain dehydrogenase reductase Sdr
LXB15_14095	COG3321	synthase
LXB15_14095	COG0604	alcohol dehydrogenase
LXB15_14095	COG1028	Short-chain dehydrogenase reductase Sdr
LXB15_14105	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LXB15_14120	COG0154	amidase activity
LXB15_14130	COG0254	rRNA binding
LXB15_14135	COG1132	(ABC) transporter
LXB15_14165	COG0483	inositol monophosphate 1-phosphatase activity
LXB15_14190	COG0318	PFAM AMP-dependent synthetase and ligase
LXB15_14205	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LXB15_14210	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LXB15_14215	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LXB15_14220	COG0457	Tetratricopeptide repeat
LXB15_14225	COG0469	pyruvate kinase activity
LXB15_14240	COG3750	Belongs to the UPF0335 family
LXB15_14245	COG4957	zinc ion binding
LXB15_14250	COG3108	Peptidase M15
LXB15_14275	COG5310	Homospermidine synthase
LXB15_14290	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LXB15_14295	COG0330	HflC and HflK could
LXB15_14305	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LXB15_14305	COG0517	IMP dehydrogenase activity
LXB15_14315	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LXB15_14335	COG0067	glutamate synthase
LXB15_14335	COG0069	glutamate synthase activity
LXB15_14335	COG0070	glutamate synthase
LXB15_14340	COG3546	catalase activity
LXB15_14345	COG1937	Protein conserved in bacteria
LXB15_14360	COG0071	Belongs to the small heat shock protein (HSP20) family
LXB15_14390	COG3706	GGDEF domain
LXB15_14390	COG2203	Gaf domain
LXB15_14390	COG5001	Diguanylate cyclase
LXB15_14390	COG4251	negative regulation of phosphorylation
LXB15_14415	COG0045	succinate-CoA ligase (ADP-forming) activity
LXB15_14415	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LXB15_14415	COG1042	CoA-binding domain protein
LXB15_14420	COG2226	methyltransferase
LXB15_14430	COG0601	transmembrane transport
LXB15_14435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LXB15_14445	COG4608	Belongs to the ABC transporter superfamily
LXB15_14470	COG0156	8-amino-7-oxononanoate synthase activity
LXB15_14490	COG1970	mechanosensitive ion channel activity
LXB15_14495	COG0784	Response regulator, receiver
LXB15_14495	COG2205	protein histidine kinase activity
LXB15_14505	COG0432	Pfam Uncharacterised protein family UPF0047
LXB15_14510	COG0657	acetylesterase activity
LXB15_14525	COG0167	dihydroorotate dehydrogenase activity
LXB15_14530	COG0784	Response regulator, receiver
LXB15_14535	COG3920	Histidine kinase
LXB15_14540	COG0534	Mate efflux family protein
LXB15_14545	COG0123	including yeast histone deacetylase and acetoin utilization protein
LXB15_14555	COG1793	dna ligase
LXB15_14610	COG1960	acyl-CoA dehydrogenase activity
LXB15_14615	COG4221	oxidoreductase activity
LXB15_14620	COG4221	oxidoreductase activity
LXB15_14645	COG1064	alcohol dehydrogenase
LXB15_14655	COG0367	asparagine synthase
LXB15_14665	COG1363	Peptidase, m42
LXB15_14675	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LXB15_14680	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LXB15_14680	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LXB15_14700	COG0583	DNA-binding transcription factor activity
LXB15_14705	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LXB15_14710	COG3485	protocatechuate 3,4-dioxygenase
LXB15_14715	COG3485	protocatechuate 3,4-dioxygenase
LXB15_14720	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LXB15_14725	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LXB15_14755	COG0686	Belongs to the AlaDH PNT family
LXB15_14760	COG1054	Belongs to the UPF0176 family
LXB15_14770	COG0861	Integral membrane protein TerC family
LXB15_14810	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LXB15_14815	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LXB15_14815	COG2010	Cytochrome c
LXB15_14835	COG4935	Belongs to the peptidase S8 family
LXB15_14835	COG1404	Belongs to the peptidase S8 family
LXB15_14900	COG0628	permease
LXB15_14945	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LXB15_14950	COG2010	Cytochrome c
LXB15_14950	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LXB15_14990	COG1278	Cold shock
LXB15_14995	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LXB15_15055	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LXB15_15070	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LXB15_15070	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LXB15_15075	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LXB15_15105	COG0668	transmembrane transport
LXB15_15125	COG3938	Belongs to the proline racemase family
LXB15_15130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LXB15_15170	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LXB15_15175	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LXB15_15195	COG0673	inositol 2-dehydrogenase activity
LXB15_15210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LXB15_15225	COG0463	Glycosyl transferase, family 2
LXB15_15250	COG0463	Glycosyl transferase, family 2
LXB15_15255	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LXB15_15265	COG2072	flavoprotein involved in K transport
LXB15_15285	COG0438	transferase activity, transferring glycosyl groups
LXB15_15330	COG1176	ABC-type spermidine putrescine transport system, permease component I
LXB15_15335	COG3842	ATPase activity
LXB15_15345	COG1917	Cupin 2, conserved barrel domain protein
LXB15_15345	COG1396	sequence-specific DNA binding
LXB15_15350	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LXB15_15385	COG0318	PFAM AMP-dependent synthetase and ligase
LXB15_15395	COG1024	Enoyl-CoA hydratase
LXB15_15410	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LXB15_15415	COG1960	acyl-CoA dehydrogenase activity
LXB15_15430	COG1309	transcriptional regulator
LXB15_15440	COG1028	Short-chain dehydrogenase reductase Sdr
LXB15_15445	COG0583	DNA-binding transcription factor activity
LXB15_15455	COG1309	transcriptional regulator
LXB15_15470	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
LXB15_15475	COG1902	pentaerythritol trinitrate reductase activity
LXB15_15490	COG0583	DNA-binding transcription factor activity
LXB15_15495	COG1028	Short-chain dehydrogenase reductase Sdr
LXB15_15520	COG1309	transcriptional regulator
LXB15_15530	COG2814	Major facilitator Superfamily
LXB15_15555	COG0180	Tryptophanyl-tRNA synthetase
LXB15_15560	COG1917	Cupin 2, conserved barrel domain protein
LXB15_15560	COG2169	Transcriptional regulator
LXB15_15570	COG1136	(ABC) transporter
LXB15_15605	COG0318	PFAM AMP-dependent synthetase and ligase
LXB15_15615	COG3273	potassium ion transport
LXB15_15615	COG0471	metal ion transport
LXB15_15620	COG0574	Belongs to the PEP-utilizing enzyme family
LXB15_15620	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LXB15_15625	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LXB15_15645	COG2189	Belongs to the N(4) N(6)-methyltransferase family
LXB15_15650	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LXB15_15665	COG0612	Peptidase, M16
LXB15_15670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LXB15_15680	COG1678	Uncharacterized ACR, COG1678
LXB15_15690	COG0678	peroxiredoxin activity
LXB15_15690	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LXB15_15695	COG0328	RNA-DNA hybrid ribonuclease activity
LXB15_15700	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LXB15_15705	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LXB15_15710	COG3346	SURF1 family
LXB15_15725	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
LXB15_15730	COG0109	protoheme IX farnesyltransferase activity
LXB15_15735	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LXB15_15750	COG0312	modulator of DNA gyrase
LXB15_15755	COG0259	pyridoxamine-phosphate oxidase activity
LXB15_15765	COG0484	heat shock protein binding
LXB15_15770	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LXB15_15790	COG0123	including yeast histone deacetylase and acetoin utilization protein
LXB15_15795	COG1722	exodeoxyribonuclease VII activity
LXB15_15800	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LXB15_15810	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LXB15_15815	COG0586	Pfam SNARE associated Golgi protein
LXB15_15820	COG1024	Enoyl-CoA hydratase
LXB15_15825	COG1960	acyl-CoA dehydrogenase activity
LXB15_15840	COG1250	3-hydroxyacyl-CoA dehydrogenase
LXB15_15840	COG1024	Enoyl-CoA hydratase
LXB15_15850	COG1960	acyl-CoA dehydrogenase activity
LXB15_15855	COG0151	Belongs to the GarS family
LXB15_15860	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LXB15_15870	COG0277	FAD linked oxidase domain protein
LXB15_15875	COG0009	L-threonylcarbamoyladenylate synthase
LXB15_15885	COG0751	glycine-tRNA ligase activity
LXB15_15890	COG0563	adenylate kinase activity
LXB15_15895	COG2852	Protein conserved in bacteria
LXB15_15900	COG2321	neutral zinc metallopeptidase
LXB15_15905	COG0752	glycyl-tRNA synthetase alpha subunit
LXB15_15935	COG0142	geranyltranstransferase activity
LXB15_15945	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LXB15_15950	COG0521	Mo-molybdopterin cofactor biosynthetic process
LXB15_15965	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LXB15_15975	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LXB15_15980	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LXB15_15985	COG0356	it plays a direct role in the translocation of protons across the membrane
LXB15_15995	COG0667	Aldo Keto reductase
LXB15_16000	COG0531	amino acid
LXB15_16005	COG4302	ethanolamine ammonia-lyase activity
LXB15_16010	COG4303	Ethanolamine ammonia lyase large subunit
LXB15_16030	COG1024	Enoyl-CoA hydratase
LXB15_16055	COG4451	ribulose bisphosphate carboxylase, small
LXB15_16080	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
LXB15_16090	COG1304	FMN binding
LXB15_16145	COG1294	oxidase, subunit
LXB15_16195	COG0729	surface antigen
LXB15_16210	COG0166	Belongs to the GPI family
LXB15_16215	COG0058	SHG alpha-glucan phosphorylase activity
LXB15_16220	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LXB15_16225	COG0297	glycogen (starch) synthase activity
LXB15_16230	COG0033	Phosphoglucomutase
LXB15_16235	COG1523	belongs to the glycosyl hydrolase 13 family
LXB15_16240	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LXB15_16250	COG1663	tetraacyldisaccharide 4'-kinase activity
LXB15_16255	COG1519	Transferase
LXB15_16270	COG0483	inositol monophosphate 1-phosphatase activity
LXB15_16275	COG0312	modulator of DNA gyrase
LXB15_16280	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LXB15_16280	COG0475	glutathione-regulated potassium exporter activity
LXB15_16295	COG0612	Peptidase, M16
LXB15_16300	COG0612	Peptidase, M16
LXB15_16305	COG0742	ribosomal rna small subunit methyltransferase
LXB15_16310	COG1187	pseudouridine synthase activity
LXB15_16315	COG0590	tRNA wobble adenosine to inosine editing
LXB15_16325	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LXB15_16335	COG0196	riboflavin kinase activity
LXB15_16345	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LXB15_16350	COG0459	protein refolding
LXB15_16355	COG0730	response to heat
LXB15_16360	COG3237	CsbD-like
LXB15_16385	COG2259	Doxx family
LXB15_16390	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LXB15_16395	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LXB15_16400	COG0124	histidyl-tRNA synthetase
LXB15_16405	COG2818	Glycosylase
LXB15_16415	COG1376	ErfK ybiS ycfS ynhG family protein
LXB15_16420	COG1388	LysM domain
LXB15_16420	COG1376	ErfK ybiS ycfS ynhG family protein
LXB15_16425	COG0247	lactate metabolic process
LXB15_16440	COG0277	FAD linked oxidase domain protein
LXB15_16455	COG0277	FAD linked oxidase domain protein
LXB15_16465	COG0247	lactate metabolic process
LXB15_16470	COG1139	Iron-sulfur cluster binding protein
LXB15_16480	COG1280	lysine exporter protein (LysE YggA)
LXB15_16505	COG1253	flavin adenine dinucleotide binding
LXB15_16515	COG0583	DNA-binding transcription factor activity
LXB15_16520	COG1570	exodeoxyribonuclease VII activity
LXB15_16535	COG2205	protein histidine kinase activity
LXB15_16540	COG1840	ABC-type Fe3 transport system, periplasmic component
LXB15_16545	COG1178	ABC-type Fe3 transport system permease component
LXB15_16555	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LXB15_16570	COG1177	transmembrane transport
LXB15_16575	COG1176	ABC-type spermidine putrescine transport system, permease component I
LXB15_16580	COG3842	ATPase activity
LXB15_16585	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LXB15_16610	COG2224	Isocitrate lyase
LXB15_16620	COG0174	glutamine synthetase
LXB15_16625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LXB15_16635	COG4251	negative regulation of phosphorylation
LXB15_16640	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LXB15_16645	COG0363	glucosamine-6-phosphate deaminase activity
LXB15_16650	COG0129	dihydroxy-acid dehydratase activity
LXB15_16705	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LXB15_16710	COG5328	Belongs to the UPF0262 family
LXB15_16715	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LXB15_16720	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LXB15_16735	COG0594	ribonuclease P activity
LXB15_16740	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LXB15_16745	COG0398	Pfam SNARE associated Golgi protein
LXB15_16755	COG5002	protein histidine kinase activity
LXB15_16770	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LXB15_16770	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LXB15_16775	COG1376	ErfK ybiS ycfS ynhG family protein
LXB15_16775	COG1388	LysM domain
LXB15_16780	COG1376	ErfK ybiS ycfS ynhG family protein
LXB15_16785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LXB15_16790	COG4232	protein-disulfide reductase activity
LXB15_16830	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LXB15_16845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LXB15_16860	COG0438	transferase activity, transferring glycosyl groups
LXB15_16885	COG2943	transferase activity, transferring hexosyl groups
LXB15_16905	COG4213	ABC transporter substrate-binding protein
LXB15_16910	COG4214	carbohydrate transport
LXB15_16920	COG1070	Carbohydrate kinase
LXB15_16925	COG2115	Belongs to the xylose isomerase family
LXB15_16930	COG1879	ABC-type sugar transport system periplasmic component
LXB15_16935	COG1172	Belongs to the binding-protein-dependent transport system permease family
LXB15_16945	COG0673	inositol 2-dehydrogenase activity
LXB15_16955	COG1609	Transcriptional regulator
LXB15_16985	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LXB15_17005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LXB15_17015	COG0242	peptide deformylase activity
LXB15_17020	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LXB15_17025	COG0101	tRNA pseudouridine synthase activity
LXB15_17030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LXB15_17035	COG0765	amino acid transport
LXB15_17040	COG0765	amino acid transport
LXB15_17045	COG1126	abc transporter atp-binding protein
LXB15_17055	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LXB15_17070	COG2171	N-acyltransferase activity
LXB15_17090	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LXB15_17095	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LXB15_17100	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LXB15_17125	COG0077	Prephenate dehydratase
LXB15_17125	COG1605	Chorismate mutase
LXB15_17130	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
LXB15_17135	COG3474	cytochrome
LXB15_17140	COG4166	transmembrane transport
LXB15_17145	COG4166	transmembrane transport
LXB15_17150	COG4174	ABC transporter (Permease)
LXB15_17155	COG4239	(ABC) transporter, permease
LXB15_17160	COG1230	cation diffusion facilitator family transporter
LXB15_17165	COG4172	Belongs to the ABC transporter superfamily
LXB15_17170	COG0494	nUDIX hydrolase
LXB15_17175	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LXB15_17185	COG0583	DNA-binding transcription factor activity
LXB15_17195	COG0791	NLP P60 protein
LXB15_17235	COG4964	Belongs to the GSP D family
LXB15_17260	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LXB15_17265	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LXB15_17270	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LXB15_17280	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
LXB15_17285	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LXB15_17300	COG1079	Belongs to the binding-protein-dependent transport system permease family
LXB15_17305	COG1079	Belongs to the binding-protein-dependent transport system permease family
LXB15_17315	COG3845	ABC transporter
LXB15_17320	COG0824	Thioesterase
LXB15_17325	COG2900	Belongs to the SlyX family
LXB15_17335	COG1744	ABC transporter substrate-binding protein PnrA-like
LXB15_17340	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LXB15_17375	COG0583	DNA-binding transcription factor activity
LXB15_17385	COG1253	flavin adenine dinucleotide binding
LXB15_17390	COG3932	Exopolysaccharide synthesis, ExoD
LXB15_17400	COG0725	ABC transporter, periplasmic molybdate-binding protein
LXB15_17405	COG4149	molybdate abc transporter
LXB15_17410	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
LXB15_17415	COG3842	ATPase activity
LXB15_17420	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LXB15_17425	COG1176	ABC-type spermidine putrescine transport system, permease component I
LXB15_17430	COG1177	transmembrane transport
LXB15_17500	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LXB15_17500	COG0512	Glutamine amidotransferase of anthranilate synthase
LXB15_17505	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LXB15_17510	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LXB15_17520	COG2017	converts alpha-aldose to the beta-anomer
LXB15_17525	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
LXB15_17535	COG2943	transferase activity, transferring hexosyl groups
LXB15_17560	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LXB15_17565	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
LXB15_17580	COG1797	cobyrinic acid a,c-diamide synthase activity
LXB15_17585	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
LXB15_17590	COG2099	Precorrin-6x reductase
LXB15_17595	COG2875	Belongs to the precorrin methyltransferase family
LXB15_17635	COG1492	cobalamin metabolic process
LXB15_17640	COG1028	Short-chain dehydrogenase reductase Sdr
LXB15_17645	COG1252	NADH dehydrogenase
LXB15_17655	COG1028	Short-chain dehydrogenase reductase Sdr
LXB15_17665	COG0840	transmembrane signaling receptor activity
LXB15_17665	COG3290	protein histidine kinase activity
LXB15_17715	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LXB15_17720	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LXB15_17730	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LXB15_17735	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LXB15_17740	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LXB15_17755	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LXB15_17760	COG0792	nuclease activity
LXB15_17765	COG1132	(ABC) transporter
LXB15_17770	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LXB15_17775	COG0588	phosphoglycerate mutase activity
LXB15_17795	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LXB15_17800	COG0569	domain protein
LXB15_17805	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LXB15_17825	COG4221	oxidoreductase activity
LXB15_17830	COG2813	Specifically methylates the guanine in position
LXB15_17835	COG1187	pseudouridine synthase activity
LXB15_17845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LXB15_17855	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
LXB15_17860	COG0837	glucose binding
LXB15_17865	COG0189	ligase activity
LXB15_17875	COG0606	chelatase, subunit chli
LXB15_17880	COG2264	protein methyltransferase activity
LXB15_17885	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LXB15_17885	COG0072	phenylalanine-tRNA ligase activity
LXB15_17895	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LXB15_17900	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LXB15_17905	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LXB15_17915	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LXB15_17935	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
LXB15_17940	COG0424	maF-like protein
LXB15_17945	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LXB15_17950	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LXB15_17990	COG1012	belongs to the aldehyde dehydrogenase family
LXB15_18010	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LXB15_18030	COG0431	NADPH-dependent FMN reductase
LXB15_18035	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LXB15_18040	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LXB15_18045	COG0842	Transport permease protein
LXB15_18050	COG1131	(ABC) transporter
LXB15_18060	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LXB15_18065	COG0756	dUTP diphosphatase activity
LXB15_18070	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LXB15_18080	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LXB15_18090	COG1278	Cold shock
LXB15_18095	COG2124	cytochrome p450
LXB15_18115	COG0450	alkyl hydroperoxide reductase
LXB15_18130	COG3158	transport of potassium into the cell
LXB15_18135	COG0628	permease
LXB15_18150	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LXB15_18155	COG2226	methyltransferase
LXB15_18160	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LXB15_18175	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LXB15_18180	COG1185	polyribonucleotide nucleotidyltransferase activity
LXB15_18190	COG0583	DNA-binding transcription factor activity
LXB15_18210	COG2022	thiamine diphosphate biosynthetic process
LXB15_18225	COG5507	3-demethylubiquinone-9 3-methyltransferase
LXB15_18240	COG1733	regulation of RNA biosynthetic process
LXB15_18245	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LXB15_18255	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LXB15_18285	COG5487	UPF0391 membrane protein
LXB15_18295	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LXB15_18305	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LXB15_18315	COG0268	Binds directly to 16S ribosomal RNA
LXB15_18325	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LXB15_18330	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LXB15_18340	COG0195	Participates in both transcription termination and antitermination
LXB15_18340	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LXB15_18345	COG0779	Required for maturation of 30S ribosomal subunits
LXB15_18350	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LXB15_18355	COG1396	sequence-specific DNA binding
LXB15_18365	COG1253	flavin adenine dinucleotide binding
LXB15_18375	COG1702	phosphate starvation-inducible protein PhoH
LXB15_18380	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LXB15_18390	COG0456	acetyltransferase
LXB15_18395	COG1214	PFAM Peptidase M22, glycoprotease
LXB15_18400	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
LXB15_18410	COG0180	Tryptophanyl-tRNA synthetase
LXB15_18420	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LXB15_18430	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LXB15_18445	COG0604	alcohol dehydrogenase
LXB15_18460	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LXB15_18460	COG0116	Belongs to the methyltransferase superfamily
LXB15_18480	COG0616	signal peptide processing
LXB15_18495	COG1137	ATPase activity
LXB15_18500	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LXB15_18505	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LXB15_18510	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LXB15_18520	COG0071	Belongs to the small heat shock protein (HSP20) family
LXB15_18525	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LXB15_18530	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
LXB15_18545	COG0745	RESPONSE REGULATOR receiver
LXB15_18550	COG2205	protein histidine kinase activity
LXB15_18560	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LXB15_18560	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LXB15_18565	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LXB15_18575	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LXB15_18580	COG2205	protein histidine kinase activity
LXB15_18585	COG3178	'Phosphotransferase
LXB15_18590	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LXB15_18595	COG5001	Diguanylate cyclase
LXB15_18600	COG2887	Belongs to the helicase family. UvrD subfamily
LXB15_18605	COG1074	ATP-dependent DNA helicase activity
LXB15_18605	COG1074	ATP-dependent DNA helicase activity
LXB15_18630	COG0159	tryptophan synthase activity
LXB15_18645	COG0133	tryptophan synthase activity
LXB15_18650	COG0135	phosphoribosylanthranilate isomerase activity
LXB15_18665	COG0471	metal ion transport
LXB15_18680	COG1376	ErfK ybiS ycfS ynhG family protein
LXB15_18695	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
LXB15_18710	COG1643	Atp-dependent helicase
LXB15_18715	COG4136	ATPase activity
LXB15_18720	COG4135	transport system, permease component
LXB15_18725	COG4134	Bacterial extracellular solute-binding protein
LXB15_18730	COG1028	Short-chain dehydrogenase reductase Sdr
LXB15_18745	COG3976	FMN-binding domain protein
LXB15_18745	COG1053	succinate dehydrogenase
LXB15_18745	COG0431	NADPH-dependent FMN reductase
LXB15_18755	COG3963	phosphatidate phosphatase activity
LXB15_18760	COG0484	heat shock protein binding
LXB15_18770	COG0443	Heat shock 70 kDa protein
LXB15_18775	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LXB15_18790	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LXB15_18790	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LXB15_18795	COG3920	Histidine kinase
LXB15_18800	COG0284	orotidine-5'-phosphate decarboxylase activity
LXB15_18820	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LXB15_18825	COG2358	TRAP transporter, solute receptor (TAXI family
LXB15_18855	COG0737	Belongs to the 5'-nucleotidase family
LXB15_18865	COG0625	glutathione transferase activity
LXB15_18875	COG1162	GTPase activity
LXB15_18880	COG1940	carbohydrate kinase activity
LXB15_18900	COG4608	Belongs to the ABC transporter superfamily
LXB15_18910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LXB15_18920	COG4166	transmembrane transport
LXB15_18940	COG3214	Protein conserved in bacteria
LXB15_18960	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LXB15_18995	COG0683	leucine binding
LXB15_19000	COG0784	Response regulator, receiver
LXB15_19000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LXB15_19000	COG2198	Histidine kinase
LXB15_19000	COG2205	protein histidine kinase activity
LXB15_19020	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LXB15_19030	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LXB15_19045	COG3300	MHYT domain
LXB15_19045	COG5001	Diguanylate cyclase
LXB15_19080	COG1802	Transcriptional regulator
LXB15_19110	COG1028	Short-chain dehydrogenase reductase Sdr
LXB15_19115	COG3246	L-lysine catabolic process to acetate
LXB15_19120	COG1028	Short-chain dehydrogenase reductase Sdr
LXB15_19130	COG1250	3-hydroxyacyl-CoA dehydrogenase
LXB15_19135	COG2076	Multidrug Resistance protein
LXB15_19140	COG1760	l-serine dehydratase
LXB15_19160	COG1968	undecaprenyl-diphosphatase activity
LXB15_19180	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LXB15_19200	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
LXB15_19215	COG2186	Transcriptional regulator
LXB15_19220	COG1172	Belongs to the binding-protein-dependent transport system permease family
LXB15_19225	COG1172	Belongs to the binding-protein-dependent transport system permease family
LXB15_19230	COG1129	ABC transporter
LXB15_19235	COG1879	ABC-type sugar transport system periplasmic component
LXB15_19250	COG3920	Histidine kinase
LXB15_19250	COG2202	Pas domain
LXB15_19285	COG0539	negative regulation of cytoplasmic translation
LXB15_19290	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LXB15_19295	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LXB15_19305	COG0131	Imidazoleglycerol-phosphate dehydratase
LXB15_19315	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LXB15_19325	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LXB15_19330	COG0596	Alpha beta hydrolase
LXB15_19335	COG0107	imidazoleglycerol-phosphate synthase activity
LXB15_19340	COG0140	phosphoribosyl-ATP diphosphatase activity
LXB15_19355	COG2197	response regulator
LXB15_19360	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LXB15_19365	COG2133	pyrroloquinoline quinone binding
LXB15_19395	COG3030	protein affecting phage T7 exclusion by the F plasmid
LXB15_19400	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
LXB15_19405	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LXB15_19410	COG0251	oxidation-reduction process
LXB15_19420	COG0237	dephospho-CoA kinase activity
LXB15_19430	COG0424	maF-like protein
LXB15_19435	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LXB15_19440	COG1981	membrane
LXB15_19445	COG3265	gluconokinase activity
LXB15_19450	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LXB15_19465	COG1331	Highly conserved protein containing a thioredoxin domain
LXB15_19470	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LXB15_19475	COG0445	tRNA wobble uridine modification
LXB15_19480	COG0357	Ribosomal RNA small subunit methyltransferase G
LXB15_19505	COG0495	leucyl-tRNA aminoacylation
LXB15_19510	COG0753	catalase activity
LXB15_19515	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LXB15_19520	COG0628	permease
LXB15_19530	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LXB15_19540	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LXB15_19555	COG0501	Belongs to the peptidase M48B family
LXB15_19560	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LXB15_19560	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LXB15_19570	COG0583	DNA-binding transcription factor activity
LXB15_19575	COG4221	oxidoreductase activity
LXB15_19600	COG0138	bifunctional purine biosynthesis protein purh
LXB15_19610	COG2902	Dehydrogenase
LXB15_19625	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
LXB15_19630	COG1704	LemA family
LXB15_19650	COG0288	reversible hydration of carbon dioxide
LXB15_19665	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LXB15_19670	COG0039	L-malate dehydrogenase activity
LXB15_19675	COG0045	succinate-CoA ligase (ADP-forming) activity
LXB15_19680	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LXB15_19690	COG0508	dehydrogenase complex catalyzes the overall conversion of
LXB15_19695	COG1028	Short-chain dehydrogenase reductase Sdr
LXB15_19725	COG1764	response to oxidative stress
LXB15_19765	COG2885	chlorophyll binding
LXB15_19775	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LXB15_19810	COG0066	3-isopropylmalate dehydratase activity
LXB15_19830	COG2863	cytochrome
LXB15_19845	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LXB15_19855	COG0587	DNA-directed DNA polymerase activity
LXB15_19870	COG2391	methyltransferase activity
LXB15_19875	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LXB15_19880	COG0789	Transcriptional regulator
LXB15_19885	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LXB15_19905	COG5001	Diguanylate cyclase
LXB15_19910	COG3586	endonuclease activity
LXB15_19960	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LXB15_19985	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
LXB15_19995	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LXB15_20000	COG2835	tetraacyldisaccharide 4'-kinase activity
LXB15_20010	COG2895	sulfate adenylyltransferase (ATP) activity
LXB15_20020	COG0175	sulfate reduction
LXB15_20030	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LXB15_20040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LXB15_20045	COG1946	Acyl-CoA thioesterase
LXB15_20050	COG0347	Belongs to the P(II) protein family
LXB15_20055	COG0004	ammonium transporteR
LXB15_20060	COG2261	transglycosylase associated protein
LXB15_20060	COG1674	ftsk spoiiie
LXB15_20070	COG0596	Alpha beta hydrolase
LXB15_20085	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LXB15_20090	COG0745	RESPONSE REGULATOR receiver
LXB15_20100	COG0243	molybdopterin cofactor binding
LXB15_20105	COG2264	protein methyltransferase activity
LXB15_20130	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LXB15_20135	COG0181	hydroxymethylbilane synthase activity
LXB15_20175	COG1247	-acetyltransferase
LXB15_20180	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LXB15_20190	COG1872	DUF167
LXB15_20210	COG1217	gtp-binding protein TYPA
LXB15_20225	COG0339	signal peptide processing
LXB15_20235	COG2814	Major facilitator Superfamily
LXB15_20255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LXB15_20260	COG1620	l-lactate permease
LXB15_20270	COG0137	argininosuccinate synthase activity
LXB15_20295	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LXB15_20305	COG3339	Conserved Protein
LXB15_20310	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LXB15_20325	COG4181	ATPase activity
LXB15_20335	COG0670	Belongs to the BI1 family
LXB15_20355	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LXB15_20360	COG4133	protoheme IX ABC transporter activity
LXB15_20365	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LXB15_20370	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LXB15_20380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LXB15_20395	COG1376	ErfK ybiS ycfS ynhG family protein
LXB15_20415	COG0552	protein localization to endoplasmic reticulum
LXB15_20425	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LXB15_20430	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LXB15_20445	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LXB15_20450	COG0287	Prephenate dehydrogenase
LXB15_20450	COG1605	Chorismate mutase
LXB15_20460	COG5001	Diguanylate cyclase
LXB15_20460	COG3300	MHYT domain
LXB15_20465	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LXB15_20475	COG0336	Belongs to the RNA methyltransferase TrmD family
LXB15_20480	COG2388	GCN5-related N-acetyl-transferase
LXB15_20490	COG0335	large ribosomal subunit rRNA binding
LXB15_20515	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LXB15_20530	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LXB15_20560	COG1053	succinate dehydrogenase
LXB15_20570	COG2009	succinate dehydrogenase
LXB15_20615	COG1132	(ABC) transporter
LXB15_20620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LXB15_20620	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LXB15_20630	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
LXB15_20635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LXB15_20640	COG0601	transmembrane transport
LXB15_20645	COG0747	negative chemotaxis
LXB15_20650	COG0297	glycogen (starch) synthase activity
LXB15_20675	COG3842	ATPase activity
LXB15_20680	COG1176	ABC-type spermidine putrescine transport system, permease component I
LXB15_20685	COG1177	transmembrane transport
LXB15_20695	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LXB15_20695	COG0446	pyridine nucleotide-disulphide oxidoreductase
LXB15_20710	COG0251	oxidation-reduction process
LXB15_20725	COG0444	Belongs to the ABC transporter superfamily
LXB15_20735	COG0601	transmembrane transport
LXB15_20740	COG0747	negative chemotaxis
LXB15_20750	COG4948	Mandelate Racemase Muconate Lactonizing
LXB15_20760	COG0745	RESPONSE REGULATOR receiver
LXB15_20765	COG2205	protein histidine kinase activity
LXB15_20790	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LXB15_20820	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LXB15_20860	COG2188	Transcriptional regulator
LXB15_20875	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LXB15_20880	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
LXB15_20890	COG4948	Mandelate Racemase Muconate Lactonizing
LXB15_20895	COG0473	3-isopropylmalate dehydrogenase activity