locus-tag	class	description
C5O00_00005	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
C5O00_00015	ENOG4109066	lysm domain bon superfamily protein
C5O00_00025	ENOG4105MYT	Heat shock protein
C5O00_00085	ENOG4105HP8	regulator of competence-specific genes
C5O00_00135	ENOG4105DY9	regulatoR
C5O00_00160	ENOG4108HRK	Histidine kinase
C5O00_00205	ENOG4105QIV	RNA polymerase
C5O00_00220	ENOG4105P8F	nudix hydrolase
C5O00_00225	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
C5O00_00230	ENOG4105EN6	Membrane
C5O00_00260	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
C5O00_00275	ENOG4105C5Q	Transcriptional regulator
C5O00_00320	ENOG4105C3M	thioredoxin reductase
C5O00_00355	ENOG4105CY0	Metallo-Beta-Lactamase
C5O00_00370	ENOG4107YZX	Universal stress protein
C5O00_00390	ENOG4107YZX	Universal stress protein
C5O00_00395	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
C5O00_00400	ENOG4105BZU	Histidine kinase
C5O00_00415	ENOG4105K63	Thioredoxin
C5O00_00420	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
C5O00_00425	ENOG4107YZX	Universal stress protein
C5O00_00505	ENOG4105EMN	RNA polymerase sigma factor
C5O00_00515	ENOG4105EUJ	GTP cyclohydrolase i
C5O00_00535	ENOG4105CRE	cytochrome C
C5O00_00540	ENOG4105DY8	decarboxylase
C5O00_00570	ENOG4107TJ9	Cytochrome
C5O00_00575	ENOG4105DBI	uridine monophosphokinase
C5O00_00585	ENOG4105CMN	Methylmalonyl-coA mutase
C5O00_00595	ENOG4105D5P	Methylmalonyl-coA mutase
C5O00_00605	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
C5O00_00615	ENOG4107QJE	Chromosome Partitioning Protein
C5O00_00620	ENOG4105FA0	parb-like partition protein
C5O00_00630	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
C5O00_00635	ENOG4105C3F	Signal peptidase i
C5O00_00660	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
C5O00_00670	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
C5O00_00680	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
C5O00_00710	ENOG41090KQ	Glyoxalase Bleomycin resistance protein (Dioxygenase
C5O00_00720	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
C5O00_00730	ENOG4105SFS	phosphoesterase RecJ domain protein
C5O00_00740	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
C5O00_00745	ENOG4105CIN	aminoacyl-histidine dipeptidase
C5O00_00755	ENOG4105CD3	dihydroorotase
C5O00_00780	ENOG4108RWN	rrna methyltransferase
C5O00_00785	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
C5O00_00790	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
C5O00_00795	ENOG41090R7	Ferric uptake
C5O00_00800	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
C5O00_00810	ENOG4105C8Y	Acetylornithine aminotransferase
C5O00_00830	ENOG4105E2X	shikimate dehydrogenase
C5O00_00845	ENOG4105DXN	mazG family
C5O00_00855	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
C5O00_00860	ENOG4107ZNS	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
C5O00_00865	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
C5O00_00900	ENOG4106WTF	Glycosyl transferase, family 2
C5O00_00905	ENOG4105CG5	Glycosyl transferase (Group 1
C5O00_00915	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
C5O00_00920	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
C5O00_00925	ENOG4107SF2	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
C5O00_00945	ENOG4105CJ1	ABC, transporter
C5O00_00965	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
C5O00_00980	ENOG4105FE9	pseudouridine synthase
C5O00_00985	ENOG4105VN1	Heat shock protein
C5O00_01005	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
C5O00_01010	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
C5O00_01030	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
C5O00_01040	ENOG4105EA8	2-Nitropropane dioxygenase
C5O00_01045	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
C5O00_01050	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
C5O00_01060	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
C5O00_01065	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
C5O00_01090	ENOG41068JE	domain protein
C5O00_01095	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
C5O00_01100	ENOG41074B2	UPF0747 protein
C5O00_01150	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
C5O00_01155	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
C5O00_01165	ENOG41083ND	50S ribosomal protein L33
C5O00_01170	ENOG4105KDC	50s ribosomal protein l28
C5O00_01175	ENOG4105CEV	competence damage-inducible protein
C5O00_01185	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
C5O00_01190	ENOG4107RZZ	dna polymerase iii epsilon subunit
C5O00_01210	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
C5O00_01220	ENOG4107RJ1	sodium solute
C5O00_01235	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
C5O00_01245	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
C5O00_01330	ENOG4105DG6	mannose-6-phosphate isomerase
C5O00_01345	ENOG4105CDV	Ompa motb domain protein
C5O00_01375	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
C5O00_01400	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C5O00_01405	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C5O00_01410	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
C5O00_01415	ENOG4107VNI	ribosomal protein l10
C5O00_01420	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
C5O00_01425	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
C5O00_01435	ENOG4105PM1	preprotein translocase subunit SecE
C5O00_01445	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
C5O00_01475	ENOG4105MS2	ribosomal subunit Interface protein
C5O00_01480	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
C5O00_01485	ENOG41083X6	30S ribosomal protein S21
C5O00_01490	ENOG4105C27	TonB-dependent Receptor Plug
C5O00_01495	ENOG4105C1G	acyl-Coa dehydrogenase
C5O00_01505	ENOG4105BZG	amino acid carrier protein
C5O00_01510	ENOG4107SVH	Potassium channel protein
C5O00_01530	ENOG4107R34	abc transporter permease protein
C5O00_01535	ENOG4105EHZ	conserved protein UCP016719
C5O00_01545	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
C5O00_01560	ENOG4105EFZ	amidohydrolase
C5O00_01585	ENOG4105CAK	Cell division ATP-binding protein ftsE
C5O00_01595	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
C5O00_01615	ENOG4105CG5	Glycosyl transferase (Group 1
C5O00_01670	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
C5O00_01680	ENOG41080XP	Cbs domain
C5O00_01700	ENOG4105CT7	inner membrane cred family protein
C5O00_01710	ENOG4105BZU	Histidine kinase
C5O00_01750	ENOG4107X35	defense response to bacterium
C5O00_01770	ENOG4105C72	UPF0176 protein
C5O00_01775	ENOG41085GJ	domain protein
C5O00_01785	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C5O00_01790	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
C5O00_01795	ENOG4108YYC	ycei family
C5O00_01810	ENOG4105CRQ	synthase (Component I)
C5O00_01815	ENOG4105DDQ	anthranilate synthase
C5O00_01820	ENOG4107RI6	Anthranilate phosphoribosyltransferase
C5O00_01825	ENOG4105DK0	Indole-3-glycerol phosphate synthase
C5O00_01830	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
C5O00_01835	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
C5O00_01840	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
C5O00_01860	ENOG4105D1Q	UPF0246 protein
C5O00_01865	ENOG4105C34	Pseudouridine synthase
C5O00_01875	ENOG4105CPF	Cell wall formation (By similarity)
C5O00_01880	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
C5O00_01885	ENOG4108RAV	Conserved protein
C5O00_01890	ENOG4105RA3	Binds directly to 16S ribosomal RNA (By similarity)
C5O00_01900	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
C5O00_01925	ENOG4105EUJ	GTP cyclohydrolase i
C5O00_01930	ENOG4105C8N	cysteinyl-tRNA synthetase
C5O00_01935	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
C5O00_01940	ENOG4107QZC	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
C5O00_01950	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
C5O00_01955	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
C5O00_01960	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
C5O00_01965	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C5O00_01975	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
C5O00_01980	ENOG4105KME	endoribonuclease L-psp
C5O00_01985	ENOG4105D7A	ATP-binding protein
C5O00_02025	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
C5O00_02090	ENOG4105IIU	Aminopeptidase
C5O00_02145	ENOG4105BZU	Histidine kinase
C5O00_02185	ENOG4105C75	arginyL-tRNA synthetase
C5O00_02195	ENOG4105CGD	Nad-dependent epimerase dehydratase
C5O00_02210	ENOG4105CJ2	(LipO)protein
C5O00_02230	ENOG4108UW5	maltose o-acetyltransferase
C5O00_02250	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
C5O00_02255	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
C5O00_02260	ENOG4108ZT0	50S ribosomal protein l17
C5O00_02265	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C5O00_02270	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
C5O00_02275	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
C5O00_02280	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C5O00_02285	ENOG410864M	50S ribosomal protein L36
C5O00_02290	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
C5O00_02295	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
C5O00_02300	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
C5O00_02305	ENOG41084HK	50S ribosomal protein L30
C5O00_02310	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
C5O00_02315	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
C5O00_02320	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
C5O00_02325	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
C5O00_02330	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
C5O00_02335	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C5O00_02340	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
C5O00_02345	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
C5O00_02350	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
C5O00_02355	ENOG4105WNB	50s ribosomal protein l29
C5O00_02360	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
C5O00_02365	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
C5O00_02370	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
C5O00_02375	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
C5O00_02380	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C5O00_02385	ENOG41082S5	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
C5O00_02390	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
C5O00_02395	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
C5O00_02400	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
C5O00_02405	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
C5O00_02410	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
C5O00_02415	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
C5O00_02425	ENOG4105C27	TonB-dependent Receptor Plug
C5O00_02440	ENOG4105C2N	RNA methyltransferase TrmH family group 3
C5O00_02450	ENOG4105D1H	recombination factor protein RarA
C5O00_02480	ENOG4105W5Q	DNA repair protein (RadC
C5O00_02495	ENOG4105DFU	Cell wall formation (By similarity)
C5O00_02510	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C5O00_02515	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
C5O00_02520	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
C5O00_02525	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
C5O00_02530	ENOG4105DGW	oligopeptidase A
C5O00_02550	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C5O00_02555	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
C5O00_02570	ENOG4105G6Z	alkaline phosphatase
C5O00_02605	ENOG4108IXY	short-chain dehydrogenase reductase
C5O00_02615	ENOG4108JYK	Dehydrogenase
C5O00_02620	ENOG4105KG3	cytidine deaminase
C5O00_02635	ENOG4105E6M	Sulphatase-modifying factor protein
C5O00_02640	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
C5O00_02645	ENOG4105D64	Mechanosensitive ion channel
C5O00_02695	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
C5O00_02710	ENOG4109015	Biopolymer transport protein exbD tolR
C5O00_02730	ENOG4105C1G	acyl-Coa dehydrogenase
C5O00_02790	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
C5O00_02810	ENOG4107QKZ	Ompa motb domain protein
C5O00_02825	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
C5O00_02835	ENOG4105CBG	Sulfatase
C5O00_02850	ENOG4105PFC	Transcriptional regulator
C5O00_02860	ENOG4105CRK	lysyL-tRNA synthetase
C5O00_02865	ENOG4105GVJ	transcriptional regulator
C5O00_02870	ENOG4105CN1	protease
C5O00_02880	ENOG4108Z12	YiaAB two helix domain-containing protein
C5O00_02910	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
C5O00_02915	ENOG4105K4H	Nlp p60 protein
C5O00_02960	ENOG4105CGP	Urocanate hydratase
C5O00_02975	ENOG4105CPP	Dehydrogenase, E1 component
C5O00_02980	ENOG4105CM2	brancheD-chain amino acid aminotransferase
C5O00_02985	ENOG4105C7S	Dehydrogenase
C5O00_03000	ENOG4105DXM	phenylacetic acid degradation protein
C5O00_03010	ENOG4105CHU	acetyl-coa acetyltransferase
C5O00_03020	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
C5O00_03025	ENOG4108UKI	Enoyl-CoA hydratase
C5O00_03030	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
C5O00_03035	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
C5O00_03040	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
C5O00_03045	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
C5O00_03050	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
C5O00_03055	ENOG4108RZE	Tetr family transcriptional regulator
C5O00_03105	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
C5O00_03120	ENOG4105CPP	Dehydrogenase, E1 component
C5O00_03135	ENOG4105C10	Electron transfer flavoprotein
C5O00_03145	ENOG4105D9N	nucleoside
C5O00_03150	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
C5O00_03185	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
C5O00_03195	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
C5O00_03200	ENOG4105CMR	udp-glucose 4-epimerase
C5O00_03270	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
C5O00_03275	ENOG4105C2N	RNA methyltransferase TrmH family group 3
C5O00_03315	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
C5O00_03325	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
C5O00_03330	ENOG41086DT	Membrane protein of unknown function
C5O00_03335	ENOG4105EV9	Alpha Beta Hydrolase
C5O00_03340	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
C5O00_03350	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
C5O00_03360	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
C5O00_03380	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
C5O00_03385	ENOG4108MRH	transcriptional regulatory protein
C5O00_03390	ENOG4108HRK	Histidine kinase
C5O00_03420	ENOG4105C7Z	Conserved Protein
C5O00_03445	ENOG41072GX	Peptidase M22 Glycoprotease
C5O00_03450	ENOG410624X	efflux transporter, rnd family, mfp subunit
C5O00_03460	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
C5O00_03465	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C5O00_03470	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C5O00_03475	ENOG4105C19	ABC transporter
C5O00_03485	ENOG4108SJC	Membrane
C5O00_03490	ENOG4108KF3	Electron transport protein SCO1 SenC
C5O00_03510	ENOG4107R3R	Cytochrome o ubiquinol oxidase subunit III
C5O00_03515	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
C5O00_03520	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
C5O00_03550	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
C5O00_03560	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
C5O00_03565	ENOG4105C6K	Malic enzyme
C5O00_03570	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
C5O00_03580	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
C5O00_03590	ENOG4105BZ9	Cytochrome C oxidase, subunit I
C5O00_03595	ENOG4105E2S	oxidase) subunit II
C5O00_03615	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
C5O00_03620	ENOG4107SFQ	iron-sulfur binding
C5O00_03625	ENOG4105Z6S	cytochrome C, class I
C5O00_03640	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
C5O00_03645	ENOG4105CHV	Transcription elongation factor NusA
C5O00_03650	ENOG41090IP	Required for maturation of 30S ribosomal subunits (By similarity)
C5O00_03655	ENOG4107YZX	Universal stress protein
C5O00_03665	ENOG4105ENE	Histidine kinase
C5O00_03670	ENOG4107XAV	metallophosphoesterase
C5O00_03710	ENOG4105K63	Thioredoxin
C5O00_03720	ENOG4105CWX	Alpha-1,2-mannosidase
C5O00_03730	ENOG4105RAK	Histidine kinase
C5O00_03750	ENOG4108DIG	cyanophycin synthetase
C5O00_03755	ENOG4105DDG	Cyanophycinase
C5O00_03760	ENOG4105D44	asparaginase
C5O00_03765	ENOG4105C2M	dna polymerase I
C5O00_03780	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
C5O00_03785	ENOG4108UJD	30S ribosomal protein S9
C5O00_03790	ENOG4105CE9	30S ribosomal protein S2
C5O00_03795	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
C5O00_03800	ENOG4105C0H	protease
C5O00_03805	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
C5O00_03810	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
C5O00_03825	ENOG4105C5S	asparaginyl-tRNA synthetase
C5O00_03830	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C5O00_03870	ENOG4105HDK	L-asparaginase
C5O00_03875	ENOG4105F8V	Hydrolase, tatD family
C5O00_03890	ENOG4107ZHV	Transcriptional regulator
C5O00_03895	ENOG4105C7S	Dehydrogenase
C5O00_03900	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
C5O00_03930	ENOG4105BZS	acriflavin resistance protein
C5O00_03940	ENOG4105C27	TonB-dependent Receptor Plug
C5O00_03945	ENOG4105C9M	aspartyl-trna synthetase
C5O00_03960	ENOG4105VEQ	Cold shock protein
C5O00_03965	ENOG4108Z6B	deaminase
C5O00_03970	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
C5O00_03985	ENOG4105C27	TonB-dependent Receptor Plug
C5O00_04020	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
C5O00_04040	ENOG41081FY	multiple antibiotic resistance (MarC)-related
C5O00_04050	ENOG4105CN1	protease
C5O00_04065	ENOG4107TPS	domain protein
C5O00_04075	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
C5O00_04080	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
C5O00_04085	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
C5O00_04090	ENOG4105DTN	riboflavin biosynthesis protein ribF
C5O00_04100	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
C5O00_04120	ENOG41090EK	ompa motb domain protein
C5O00_04125	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
C5O00_04130	ENOG4105CJW	magnesium transporter
C5O00_04145	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
C5O00_04150	ENOG4105WH1	Two component transcriptional regulator luxr family
C5O00_04190	ENOG4108UXE	Protein tyrosine phosphatase
C5O00_04205	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
C5O00_04255	ENOG4105CFH	Aspartokinase
C5O00_04265	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
C5O00_04280	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
C5O00_04285	ENOG4105BZU	Histidine kinase
C5O00_04295	ENOG4105EIN	peptidylprolyl cis-trans isomerase
C5O00_04310	ENOG4108JA2	transcriptioN-repair coupling factor
C5O00_04315	ENOG41080R2	UPF0102 protein
C5O00_04320	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
C5O00_04335	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
C5O00_04340	ENOG4105CYC	Transferase
C5O00_04435	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
C5O00_04450	ENOG4108UUM	single-stranded DNA-binding protein
C5O00_04470	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
C5O00_04475	ENOG4107QX3	carboxylase
C5O00_04480	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
C5O00_04490	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
C5O00_04510	ENOG41060VI	Involved in DNA repair and RecF pathway recombination (By similarity)
C5O00_04530	ENOG4105C28	cystathionine
C5O00_04545	ENOG4105DWP	Membrane
C5O00_04570	ENOG4105UTB	Blue (Type 1) copper domain protein
C5O00_04595	ENOG4105EAA	nucleoside
C5O00_04620	ENOG4105DSJ	YicC domain protein
C5O00_04625	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
C5O00_04630	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
C5O00_04640	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
C5O00_04655	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
C5O00_04670	ENOG4105CHH	sulfate transporter
C5O00_04690	ENOG4107QVM	von Willebrand factor, type A
C5O00_04695	ENOG4107QVM	von Willebrand factor, type A
C5O00_04710	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
C5O00_04715	ENOG4107QM2	Aldo Keto reductase
C5O00_04730	ENOG4105EMU	Dehydrogenase
C5O00_04770	ENOG4105C26	Dehydrogenase
C5O00_04775	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
C5O00_04780	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
C5O00_04790	ENOG4105D44	asparaginase
C5O00_04795	ENOG4105KAC	Antibiotic biosynthesis monooxygenase
C5O00_04805	ENOG4108JQB	penicillin-binding protein 1C
C5O00_04810	ENOG4105E2D	ec 3.2.1.52
C5O00_04815	ENOG4106N3A	copper homeostasis protein cutc
C5O00_04825	ENOG41080ZE	Adenylate cyclase
C5O00_04850	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
C5O00_04855	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
C5O00_04860	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
C5O00_04865	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
C5O00_04870	ENOG4108B1Q	Ribonuclease
C5O00_04880	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
C5O00_04890	ENOG4105CPQ	Dehydrogenase
C5O00_04900	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
C5O00_04905	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
C5O00_04945	ENOG4107QI1	Mate efflux family protein
C5O00_04950	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
C5O00_04955	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
C5O00_04965	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
C5O00_04975	ENOG4108RG0	uracil-dna glycosylase
C5O00_04990	ENOG4107T8J	thymidine kinase
C5O00_04995	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
C5O00_05000	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
C5O00_05005	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
C5O00_05020	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
C5O00_05035	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
C5O00_05045	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
C5O00_05050	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
C5O00_05055	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
C5O00_05060	ENOG4105WXV	50S ribosomal protein L32
C5O00_05070	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
C5O00_05075	ENOG4108R6K	riboflavin synthase, subunit alpha
C5O00_05090	ENOG4108ZVT	methylmalonyl-coA epimerase
C5O00_05095	ENOG4105H4N	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
C5O00_05100	ENOG4105D60	lipoprotein releasing system transmembrane protein
C5O00_05105	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
C5O00_05110	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
C5O00_05115	ENOG4108HRK	Histidine kinase
C5O00_05135	ENOG4105C8F	Beta-lactamase domain protein
C5O00_05150	ENOG4105WG6	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
C5O00_05170	ENOG4105BZU	Histidine kinase
C5O00_05175	ENOG4107YB6	acetyltransferase, (GNAT) family
C5O00_05180	ENOG4105PGM	cation diffusion facilitator family transporter
C5O00_05185	ENOG4108YZG	isomerase
C5O00_05195	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
C5O00_05210	ENOG4105KRF	dihydroneopterin aldolase
C5O00_05215	ENOG4105CX6	glutaminyL-tRNA synthetase
C5O00_05240	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
C5O00_05250	ENOG41080AX	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
C5O00_05255	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
C5O00_05270	ENOG4105BZA	Phosphoglycerate kinase
C5O00_05275	ENOG4107X35	defense response to bacterium
C5O00_05285	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
C5O00_05315	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
C5O00_05345	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
C5O00_05370	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
C5O00_05375	ENOG4108IAJ	Nad-dependent epimerase dehydratase
C5O00_05380	ENOG4105D3Q	Sugar transferase
C5O00_05395	ENOG4105C12	Phosphoribosylglycinamide synthetase
C5O00_05420	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
C5O00_05445	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
C5O00_05450	ENOG4105VH4	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
C5O00_05455	ENOG4107Z65	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
C5O00_05460	ENOG4107Z4P	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
C5O00_05465	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
C5O00_05470	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
C5O00_05485	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
C5O00_05490	ENOG4108J3C	UTP-glucose-1-phosphate uridylyltransferase
C5O00_05530	ENOG4105C31	Tryptophanyl-tRNA synthetase
C5O00_05550	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
C5O00_05555	ENOG4105C72	UPF0176 protein
C5O00_05560	ENOG4105MA4	psp1 domain protein
C5O00_05565	ENOG410647Z	gliding motility-associated lipoprotein GldH
C5O00_05570	ENOG4108JQC	penicillin-binding protein 1A
C5O00_05575	ENOG4107QP7	CoA-transferase subunit A
C5O00_05580	ENOG4105WH1	Two component transcriptional regulator luxr family
C5O00_05590	ENOG4108IIH	CoA-transferase subunit B
C5O00_05595	ENOG4108JQ6	ABC transporter
C5O00_05610	ENOG4107QK9	Beta-lactamase
C5O00_05615	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
C5O00_05620	ENOG4105BZU	Histidine kinase
C5O00_05630	ENOG4105D52	delta-aminolevulinic acid dehydratase
C5O00_05635	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
C5O00_05640	ENOG4105EXN	Sulfate transport protein CysZ
C5O00_05650	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
C5O00_05660	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
C5O00_05665	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
C5O00_05675	ENOG4107SF0	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
C5O00_05685	ENOG4105CSR	polyphosphate kinase 2
C5O00_05690	ENOG4105CSR	polyphosphate kinase 2
C5O00_05710	ENOG4105E39	Enoyl-CoA hydratase
C5O00_05735	ENOG4108Y6J	UPF0403 protein
C5O00_05740	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
C5O00_05755	ENOG4105DSE	periplasmic solute binding protein
C5O00_05760	ENOG4105DIK	(ABC) transporter
C5O00_05765	ENOG4107RPQ	ABC transporter
C5O00_05770	ENOG4107RBD	ABC, transporter
C5O00_05780	ENOG4105CE1	Ferrous iron transport protein b
C5O00_05790	ENOG4108KF3	Electron transport protein SCO1 SenC
C5O00_05795	ENOG4105DZP	Membrane-associated zinc metalloprotease
C5O00_05805	ENOG41082IR	Excinuclease ABC C subunit domain protein
C5O00_05810	ENOG4105EQD	regulatoR
C5O00_05830	ENOG4107QX9	Thiol disulfide interChange protein
C5O00_05860	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
C5O00_05865	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
C5O00_05880	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
C5O00_05885	ENOG4105EPC	oxidoreductase
C5O00_05900	ENOG4105EXW	epimerase dehydratase
C5O00_05910	ENOG4105C9K	Endothelin-converting enzyme 1
C5O00_05915	ENOG4108535	NAD dependent epimerase/dehydratase family
C5O00_05925	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
C5O00_05940	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
C5O00_05955	ENOG4105BZU	Histidine kinase
C5O00_05970	ENOG4107XQK	5-formyltetrahydrofolate cyclo-ligase
C5O00_05980	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
C5O00_05985	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
C5O00_05995	ENOG4105F1J	Homogentisate 1,2-dioxygenase
C5O00_06000	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
C5O00_06050	ENOG4105UYK	outer membrane protein a
C5O00_06075	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
C5O00_06090	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
C5O00_06095	ENOG4105VG1	fes assembly suf system protein
C5O00_06100	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
C5O00_06110	ENOG4105C9B	Cysteine desulfurase
C5O00_06180	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
C5O00_06195	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
C5O00_06205	ENOG4107T6F	Xaa-Pro aminopeptidase
C5O00_06230	ENOG4105E33	succinate dehydrogenase
C5O00_06235	ENOG4105BZU	Histidine kinase
C5O00_06240	ENOG4105CHM	Aminotransferase
C5O00_06260	ENOG4105MJ2	Competence protein
C5O00_06270	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
C5O00_06300	ENOG4105CGK	Exodeoxyribonuclease III
C5O00_06305	ENOG4105ER2	Ompa motb domain protein
C5O00_06310	ENOG4105CPC	Aldo Keto reductase
C5O00_06320	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
C5O00_06325	ENOG4105BZU	Histidine kinase
C5O00_06375	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
C5O00_06380	ENOG4107RWD	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
C5O00_06385	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
C5O00_06395	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
C5O00_06420	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
C5O00_06425	ENOG41082MC	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
C5O00_06435	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
C5O00_06440	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
C5O00_06445	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
C5O00_06460	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
C5O00_06485	ENOG4105C03	ribonuclease
C5O00_06490	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
C5O00_06500	ENOG4108UUM	single-stranded DNA-binding protein
C5O00_06505	ENOG4105C37	(CBS) domain
C5O00_06525	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
C5O00_06530	ENOG4105K46	50S ribosomal protein l27
C5O00_06545	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
C5O00_06555	ENOG4108RCS	geranylgeranylglyceryl phosphate synthase
C5O00_06575	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
C5O00_06590	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
C5O00_06610	ENOG4105EW6	flavin reductase domain protein, FMN-binding
C5O00_06620	ENOG4105CRW	Short chain fatty acid transporter
C5O00_06625	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
C5O00_06635	ENOG4107VPC	Peptidyl-arginine deiminase
C5O00_06645	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
C5O00_06660	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
C5O00_06665	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
C5O00_06680	ENOG4107RJ9	Cell division protein FtsX
C5O00_06690	ENOG4105C8T	Leucyl-tRNA synthetase
C5O00_06705	ENOG4105M08	Membrane
C5O00_06710	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
C5O00_06725	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
C5O00_06730	ENOG4105CD3	dihydroorotase
C5O00_06745	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
C5O00_06765	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C5O00_06770	ENOG4105BZU	Histidine kinase
C5O00_06775	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
C5O00_06780	ENOG4107UGT	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
C5O00_06805	ENOG4105CAY	ferredoxin--nadp reductase
C5O00_06810	ENOG4108ZIT	Ferredoxin, 2FE-2S
C5O00_06820	ENOG4105C1G	acyl-Coa dehydrogenase
C5O00_06825	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
C5O00_06830	ENOG4107YAY	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
C5O00_06835	ENOG4105K5M	30s ribosomal protein S16
C5O00_06845	ENOG4105C0B	DNA polymerase III (alpha subunit)
C5O00_06855	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
C5O00_06905	ENOG4105BZU	Histidine kinase
C5O00_06940	ENOG4105BZU	Histidine kinase
C5O00_06965	ENOG4105CVR	type I restriction-modification system
C5O00_06975	ENOG4105EKX	Restriction modification system DNA (Specificity
C5O00_06980	ENOG4105DZR	Type I site-specific deoxyribonuclease
C5O00_06995	ENOG4108V0P	LemA family
C5O00_07025	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
C5O00_07030	ENOG4107EEP	NADH dehydrogenase (quinone) (EC 1.6.99.5)
C5O00_07035	ENOG4108IEG	Formate dehydrogenase Alpha subunit
C5O00_07040	ENOG4105XRQ	Xanthine dehydrogenase accessory factor
C5O00_07050	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
C5O00_07055	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
C5O00_07065	ENOG4105D06	uba thif-type nad fad binding protein
C5O00_07075	ENOG41080H2	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
C5O00_07085	ENOG4105F4R	Transcriptional regulator mode
C5O00_07090	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
C5O00_07120	ENOG4107T7F	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
C5O00_07160	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
C5O00_07170	ENOG4105CSA	Coproporphyrinogen iii oxidase
C5O00_07295	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
C5O00_07325	ENOG4107UBA	reductase
C5O00_07335	ENOG4105FJH	Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity)
C5O00_07365	ENOG4105CBX	hi0933 family
C5O00_07405	ENOG4107S1E	Beta-lactamase
C5O00_07425	ENOG4105FE9	pseudouridine synthase
C5O00_07470	ENOG4107VAM	peptidase, m28
C5O00_07485	ENOG4105CND	Glycosyl transferase, family 2
C5O00_07490	ENOG4105K64	Glycosyl transferase, family 2
C5O00_07515	ENOG4107QZF	nitrite reductase NADPH large subunit
C5O00_07540	ENOG4105CJ3	phosphate transporter
C5O00_07545	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
C5O00_07550	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
C5O00_07580	ENOG4107RUZ	Sss sodium solute transporter superfamily
C5O00_07585	ENOG4107Y7Q	pfkb domain protein
C5O00_07600	ENOG4105CT4	transporter
C5O00_07645	ENOG4105C27	TonB-dependent Receptor Plug
C5O00_07655	ENOG4105ETE	Transcriptional regulator (LacI family
C5O00_07660	ENOG4108HKT	sucrose-6-phosphate hydrolase
C5O00_07675	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
C5O00_07700	ENOG4105C37	(CBS) domain
C5O00_07725	ENOG4105DUX	Transporter
C5O00_07730	ENOG4105DUX	Transporter
C5O00_07740	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
C5O00_07745	ENOG4107TT5	NLP P60 protein
C5O00_07750	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
C5O00_07760	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
C5O00_07765	ENOG4105CN1	protease
C5O00_07770	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C5O00_07780	ENOG4105CNI	cell division protein FtsW
C5O00_07800	ENOG4105DFF	Rod shape-determining protein mreb
C5O00_07805	ENOG4105DC1	bifunctional purine biosynthesis protein purh
C5O00_07855	ENOG4105C27	TonB-dependent Receptor Plug
C5O00_07865	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
C5O00_07870	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
C5O00_07890	ENOG4108JU7	Transcriptional regulator
C5O00_07895	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
C5O00_07915	ENOG4105E6M	Sulphatase-modifying factor protein
C5O00_07935	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
C5O00_07945	ENOG4105C5H	ABC transporter
C5O00_07965	ENOG4105EE5	Membrane protein terC
C5O00_08040	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
C5O00_08045	ENOG4105D6J	arsenicaL-resistance protein
C5O00_08060	ENOG41080HT	Transcriptional regulator, arsr family
C5O00_08155	ENOG4105C72	UPF0176 protein
C5O00_08160	ENOG4105D3R	alkyl hydroperoxide reductase
C5O00_08165	ENOG4107TPS	domain protein
C5O00_08170	ENOG41087NI	Sulfite exporter TauE/SafE
C5O00_08180	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
C5O00_08190	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
C5O00_08230	ENOG4108V0P	LemA family
C5O00_08240	ENOG4105DR5	peptidase
C5O00_08245	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
C5O00_08285	ENOG4105WH1	Two component transcriptional regulator luxr family
C5O00_08290	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
C5O00_08300	ENOG4105CFH	Aspartokinase
C5O00_08305	ENOG4107RDY	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
C5O00_08310	ENOG4105D98	threonine synthase
C5O00_08315	ENOG4105C28	cystathionine
C5O00_08320	ENOG4105CFH	Aspartokinase
C5O00_08325	ENOG4105II7	pyrroline-5-carboxylate reductase
C5O00_08330	ENOG4108UKZ	OsmC family
C5O00_08335	ENOG4105C3R	Methionine synthase
C5O00_08340	ENOG4105C3R	Methionine synthase
C5O00_08345	ENOG4105SYT	Methylenetetrahydrofolate reductase
C5O00_08350	ENOG4107YXA	Transcriptional regulator, BadM Rrf2 family
C5O00_08355	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
C5O00_08390	ENOG4105CQC	Prephenate dehydratase
C5O00_08395	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
C5O00_08405	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
C5O00_08410	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
C5O00_08430	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
C5O00_08440	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
C5O00_08465	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
C5O00_08470	ENOG4105WH1	Two component transcriptional regulator luxr family
C5O00_08475	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
C5O00_08495	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
C5O00_08505	ENOG4107YM1	mraZ protein
C5O00_08510	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
C5O00_08520	ENOG4105CJN	penicillin-binding protein
C5O00_08525	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
C5O00_08530	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
C5O00_08535	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
C5O00_08540	ENOG4105CNI	cell division protein FtsW
C5O00_08545	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
C5O00_08550	ENOG4105DFU	Cell wall formation (By similarity)
C5O00_08560	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
C5O00_08565	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
C5O00_08570	ENOG4105KTH	gatB Yqey
C5O00_08605	ENOG4105C59	p-type ATPase
C5O00_08615	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
C5O00_08625	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
C5O00_08630	ENOG4105C58	cytochrome c oxidase accessory protein ccog
C5O00_08645	ENOG4105D4P	Coproporphyrinogen iii oxidase
C5O00_08660	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
C5O00_08675	ENOG4105DJV	ribulose-phosphate 3-epimerase
C5O00_08685	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C5O00_08690	ENOG4105BZU	Histidine kinase
C5O00_08695	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
C5O00_08700	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
C5O00_08715	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
C5O00_08720	ENOG4105D2N	Aldolase
C5O00_08730	ENOG4108RWN	rrna methyltransferase
C5O00_08740	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
C5O00_08745	ENOG4105C1A	potassium transporter peripheral membrane
C5O00_08750	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
C5O00_08755	ENOG4105CHM	Aminotransferase
C5O00_08765	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
C5O00_08770	ENOG4105C26	Dehydrogenase
C5O00_08780	ENOG4105NWN	ApaG protein
C5O00_08800	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
C5O00_08805	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
C5O00_08810	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
C5O00_08815	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
C5O00_08825	ENOG41061HS	cysteine-type endopeptidase activity
C5O00_08850	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
C5O00_08865	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
C5O00_08870	ENOG4108K0D	peptidase, M48
C5O00_08875	ENOG4108VXD	carboxy-peptidase
C5O00_08880	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
C5O00_08900	ENOG4108CSZ	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
C5O00_08920	ENOG4105BZU	Histidine kinase
C5O00_08925	ENOG4105WH1	Two component transcriptional regulator luxr family
C5O00_08940	ENOG4105CHR	reductase
C5O00_08955	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
C5O00_08960	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
C5O00_08985	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
C5O00_08995	ENOG4107U7B	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
C5O00_09005	ENOG4105EGD	dinuclear metal center protein, YbgI family
C5O00_09010	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
C5O00_09015	ENOG4105BZU	Histidine kinase
C5O00_09020	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
C5O00_09025	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
C5O00_09030	ENOG4105K3M	)-transporter
C5O00_09040	ENOG4107QJZ	Glycosyl transferase, family 2
C5O00_09055	ENOG4107R0I	Cell wall formation (By similarity)
C5O00_09060	ENOG4105CHM	Aminotransferase
C5O00_09065	ENOG4105DZP	Membrane-associated zinc metalloprotease
C5O00_09075	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
C5O00_09085	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
C5O00_09090	ENOG4105KNE	Phosphatidate cytidylyltransferase
C5O00_09100	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
C5O00_09105	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
C5O00_09120	ENOG4107RIV	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
C5O00_09125	ENOG41062IR	nudix hydrolase
C5O00_09140	ENOG4108UVJ	appr-1-p processing domain protein
C5O00_09145	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
C5O00_09160	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
C5O00_09165	ENOG4105BZ1	(ABC) transporter
C5O00_09175	ENOG4105C8B	TIGR00159 family
C5O00_09180	ENOG4105EEI	dihydropteroate synthase
C5O00_09195	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
C5O00_09200	ENOG4105CP7	Triose-phosphate isomerase
C5O00_09205	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
C5O00_09220	ENOG4105VC4	domain protein
C5O00_09225	ENOG4105VC4	domain protein
C5O00_09230	ENOG4105VC4	domain protein
C5O00_09235	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
C5O00_09280	ENOG4108WYR	Curli production assembly transport component, CsgF
C5O00_09285	ENOG4105P8Q	Curli production assembly transport component CsgG
C5O00_09295	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
C5O00_09300	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
C5O00_09305	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
C5O00_09325	ENOG4105D5P	Methylmalonyl-coA mutase
C5O00_09355	ENOG4105WMR	Protein CrcB homolog
C5O00_09385	ENOG4105CM2	brancheD-chain amino acid aminotransferase
C5O00_09395	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
C5O00_09400	ENOG4105ECP	epimerase
C5O00_09410	ENOG4107XPB	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C5O00_09415	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
C5O00_09420	ENOG4108IUX	(ABC) transporter
C5O00_09425	ENOG4105RHA	ABC transporter, permease
C5O00_09430	ENOG4105EGS	Mechanosensitive ion channel
C5O00_09440	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C5O00_09445	ENOG4105CSR	polyphosphate kinase 2
C5O00_09485	ENOG4105CKK	Glycosyl transferase, family 2
C5O00_09490	ENOG4108IAJ	Nad-dependent epimerase dehydratase
C5O00_09515	ENOG4105EMN	RNA polymerase sigma factor
C5O00_09535	ENOG4105EMN	RNA polymerase sigma factor
C5O00_09555	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
C5O00_09580	ENOG4105C19	ABC transporter
C5O00_09590	ENOG4105C5H	ABC transporter
C5O00_09605	ENOG4105D3Q	Sugar transferase
C5O00_09610	ENOG4107QQG	Dehydrogenase
C5O00_09625	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
C5O00_09655	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
C5O00_09660	ENOG4107RBS	Methyltransferase
C5O00_09690	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
C5O00_09695	ENOG4105C30	Nad-dependent epimerase dehydratase
C5O00_09710	ENOG4107T8Q	Glycosyl transferase (Group 1
C5O00_09720	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
C5O00_09755	ENOG4105D2T	synthase
C5O00_09820	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
C5O00_09825	ENOG4108IUZ	ABC transporter
C5O00_09835	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
C5O00_09840	ENOG4105C2X	Arabinose 5-phosphate isomerase
C5O00_09845	ENOG4105C9U	ATP-dependent DNA helicase RecQ
C5O00_09850	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
C5O00_09855	ENOG4108YYS	metal-dependent hydrolase (By similarity)
C5O00_09870	ENOG4108Z7R	Chaperone CsaA
C5O00_09880	ENOG4105BZU	Histidine kinase
C5O00_09890	ENOG4105CHH	sulfate transporter
C5O00_09905	ENOG4105BZ1	(ABC) transporter
C5O00_09910	ENOG4107RDP	Dehydrogenase
C5O00_09915	ENOG4107R6T	Involved in the transcription termination process (By similarity)
C5O00_09925	ENOG4105VIE	preprotein translocase, subunit YajC
C5O00_09930	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
C5O00_09935	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
C5O00_09945	ENOG410829K	Lysine exporter protein (Lyse ygga)
C5O00_09955	ENOG4105CGH	5'-nucleotidase
C5O00_09965	ENOG41079HR	Phosphate-Selective Porin O and P
C5O00_09985	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
C5O00_10005	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
C5O00_10015	ENOG41085KW	ppic-type peptidyL-prolyl cis-trans isomerase
C5O00_10020	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
C5O00_10025	ENOG4105EXC	Acyl-transferase
C5O00_10030	ENOG4108I0Z	Aconitate hydratase
C5O00_10040	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C5O00_10060	ENOG4105EWK	phytoene
C5O00_10080	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
C5O00_10085	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
C5O00_10090	ENOG4105VEJ	Heat shock protein
C5O00_10110	ENOG4105CV1	Transketolase (EC 2.2.1.1)
C5O00_10115	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
C5O00_10130	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
C5O00_10135	ENOG4105CDU	Replicative dna helicase
C5O00_10150	ENOG4108ZG0	Ompa motb domain protein
C5O00_10155	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
C5O00_10160	ENOG4105VJV	50s ribosomal protein L35
C5O00_10165	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
C5O00_10170	ENOG4105C22	threonyL-tRNA synthetase
C5O00_10220	ENOG4108VAC	response regulator
C5O00_10225	ENOG4105C2F	Histidine kinase
C5O00_10235	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C5O00_10250	ENOG4105BZW	Glycerate kinase
C5O00_10265	ENOG4105E9K	Isocitrate dehydrogenase
C5O00_10270	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
C5O00_10275	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
C5O00_10285	ENOG4105KD7	acetyltransferase
C5O00_10290	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
C5O00_10300	ENOG4105C0H	protease
C5O00_10305	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
C5O00_10315	ENOG4105HHA	aminodeoxychorismate lyase
C5O00_10325	ENOG4105QD8	tetrapyrrole corrin porphyrin
C5O00_10335	ENOG4105KJF	protein tyrosine phosphatase
C5O00_10340	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
C5O00_10350	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
C5O00_10360	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
C5O00_10365	ENOG4108MJ3	acetyltransferase
C5O00_10370	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
C5O00_10375	ENOG4108URH	decarboxylase
C5O00_10380	ENOG4105CYP	glycoside hydrolase, family
C5O00_10385	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
C5O00_10395	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
C5O00_10420	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
C5O00_10425	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
C5O00_10440	ENOG4105K64	Glycosyl transferase, family 2
C5O00_10450	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
C5O00_10465	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
C5O00_10470	ENOG4105EYW	Ion transport protein
C5O00_10475	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
C5O00_10480	ENOG4105DFA	alanine racemase domain protein
C5O00_10490	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
C5O00_10495	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
C5O00_10500	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
C5O00_10520	ENOG4105CZ9	Domain of unknown function (DU1801)
C5O00_10530	ENOG4108NEV	two component transcriptional regulator, LytTR family
C5O00_10535	ENOG4108HRK	Histidine kinase
C5O00_10545	ENOG4105CKU	formyltetrahydrofolate synthetase
C5O00_10555	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
C5O00_10575	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
C5O00_10595	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
C5O00_10600	ENOG4105E18	UPF0276 protein
C5O00_10620	ENOG4105WH1	Two component transcriptional regulator luxr family
C5O00_10640	ENOG4105C27	TonB-dependent Receptor Plug
C5O00_10655	ENOG4105E1F	short-chain dehydrogenase reductase
C5O00_10660	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
C5O00_10670	ENOG4105C5H	ABC transporter
C5O00_10710	ENOG4105VEQ	Cold shock protein
C5O00_10725	ENOG4105CD8	aminopeptidase N
C5O00_10750	ENOG4108VAC	response regulator
C5O00_10755	ENOG4105CBC	glutamate synthase
C5O00_10770	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
C5O00_10785	ENOG4106BQ7	Glycosyl Transferase
C5O00_10810	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
C5O00_10815	ENOG4107W2A	UPF0173 metal-dependent hydrolase
C5O00_10820	ENOG4105DTQ	mandelate racemase muconate lactonizing
C5O00_10850	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
C5O00_10860	ENOG4107QX3	carboxylase
C5O00_10870	ENOG4105C5H	ABC transporter
C5O00_10880	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
C5O00_10890	ENOG4105CCS	Glutamate formiminotransferase
C5O00_10895	ENOG41088SP	formiminoglutamate hydrolase
C5O00_10900	ENOG4105CI2	imidazolone-5-propionate hydrolase
C5O00_10905	ENOG4105C28	cystathionine
C5O00_10910	ENOG4105FJR	Lmbe family
C5O00_10940	ENOG4105IIU	Aminopeptidase
C5O00_10975	ENOG4105CRE	cytochrome C
C5O00_11000	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
C5O00_11015	ENOG4108IJF	Heavy metal efflux pump, CzcA
C5O00_11030	ENOG4105C59	p-type ATPase
C5O00_11040	ENOG4105C59	p-type ATPase
C5O00_11060	ENOG41090R7	Ferric uptake
C5O00_11085	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
C5O00_11090	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
C5O00_11105	ENOG4105CNU	cell division protein FtsK
C5O00_11125	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
C5O00_11130	ENOG4105DFD	Na H antiporter
C5O00_11150	ENOG4105C28	cystathionine
C5O00_11155	ENOG4108YXU	transcriptional regulator AsnC family
C5O00_11160	ENOG4107QN2	dihydrolipoyl dehydrogenase
C5O00_11180	ENOG4105CRQ	synthase (Component I)
C5O00_11185	ENOG4107THF	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
C5O00_11205	ENOG4107URF	beta-phospho-glucomutase
C5O00_11215	ENOG4107T9C	Alpha amylase catalytic region
C5O00_11225	ENOG4105CTQ	phosphohexokinase
C5O00_11240	ENOG4107QP8	phosphohexose isomerase
C5O00_11265	ENOG4105C0P	Mg chelatase subunit ChlI
C5O00_11285	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
C5O00_11290	ENOG4105E7W	lamb ycsf family protein
C5O00_11295	ENOG4105P4J	Allophanate hydrolase, subunit 1
C5O00_11300	ENOG4107R7A	Allophanate hydrolase subunit 2
C5O00_11320	ENOG4105BZU	Histidine kinase
C5O00_11335	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
C5O00_11345	ENOG4105EJQ	L-serine dehydratase
C5O00_11350	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
C5O00_11355	ENOG4105VC4	domain protein
C5O00_11360	ENOG4105C0B	DNA polymerase III (alpha subunit)
C5O00_11375	ENOG4105CFG	Acts as a chaperone (By similarity)
C5O00_11405	ENOG4105D9P	serine threonine protein kinase
C5O00_11450	ENOG4105DKQ	ROK family
C5O00_11465	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
C5O00_11505	ENOG4107R91	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
C5O00_11510	ENOG41070F3	Catalyzes the ATP-dependent phosphorylation of maltose to maltose 1-phosphate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, GlgE and GlgB (By similarity)
C5O00_11515	ENOG4107S9Q	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
C5O00_11535	ENOG4105KA0	thioesterase Superfamily protein
C5O00_11540	ENOG4105E4F	Isochorismate synthase
C5O00_11545	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
C5O00_11560	ENOG4105QNR	S1 RNA binding domain protein
C5O00_11600	ENOG4105CAQ	asparagine synthetase
C5O00_11605	ENOG4105CPP	Dehydrogenase, E1 component
C5O00_11620	ENOG4108URH	decarboxylase
C5O00_11625	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
C5O00_11635	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
C5O00_11645	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
C5O00_11665	ENOG4105MPN	Membrane
C5O00_11670	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C5O00_11695	ENOG4108RMU	ferritin dps family protein
C5O00_11700	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
C5O00_11710	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
C5O00_11715	ENOG4105C11	sulfate adenylyltransferase), subunit 2
C5O00_11735	ENOG4105PNM	synthesis protein
C5O00_11750	ENOG4105D3Q	Sugar transferase
C5O00_11755	ENOG4105D7W	serine acetyltransferase
C5O00_11760	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
C5O00_11775	ENOG4105D75	Capsular exopolysaccharide family
C5O00_11810	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
C5O00_11825	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
C5O00_11850	ENOG4105C9A	Phoh family
C5O00_11855	ENOG4107QWK	SAICAR synthetase
C5O00_11870	ENOG4105BZG	amino acid carrier protein
C5O00_11880	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
C5O00_11885	ENOG4105CN9	Peptidase m42 family protein
C5O00_11920	ENOG4108UT2	hemolysin iii
C5O00_11930	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
C5O00_11945	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
C5O00_11950	ENOG4105C8Y	Acetylornithine aminotransferase
C5O00_11980	ENOG4107QI6	Cysteine desulfurase
C5O00_12010	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
C5O00_12015	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
C5O00_12045	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
C5O00_12050	ENOG4107QN2	dihydrolipoyl dehydrogenase
C5O00_12060	ENOG4105E0X	reductase
C5O00_12065	ENOG4105E0X	reductase
C5O00_12080	ENOG4105DEU	major facilitator superfamily
C5O00_12105	ENOG4105GFR	rna polymerase sigma factor
C5O00_12110	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
C5O00_12120	ENOG4105CAT	Cytidine monophosphate kinase
C5O00_12135	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
C5O00_12140	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
C5O00_12145	ENOG4105CXT	aspartate transcarbamylase
C5O00_12160	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
C5O00_12170	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
C5O00_12185	ENOG4105C6E	dna polymerase iii
C5O00_12210	ENOG4105C7H	Helicase, RecD TraA family
C5O00_12215	ENOG4107RJC	Iron-containing alcohol dehydrogenase
C5O00_12225	ENOG4105CDY	transcriptional regulatory protein
C5O00_12235	ENOG4105CN1	protease
C5O00_12240	ENOG4105KZX	Pterin carbinolamine dehydratase
C5O00_12250	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
C5O00_12255	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
C5O00_12260	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C5O00_12265	ENOG4105C84	Histidine ammonia-lyase
C5O00_12295	ENOG4107SN7	NLP P60 protein
C5O00_12300	ENOG4105CHU	acetyl-coa acetyltransferase
C5O00_12310	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
C5O00_12320	ENOG4105E6M	Sulphatase-modifying factor protein
C5O00_12365	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
C5O00_12385	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
C5O00_12390	ENOG4107KIA	Virulence factor Mce family protein
C5O00_12395	ENOG4105DF6	Fe-S oxidoreductase
C5O00_12405	ENOG4105DF6	Fe-S oxidoreductase
C5O00_12415	ENOG4105D17	glycoside hydrolase, family 3 domain protein
C5O00_12420	ENOG4105CPK	Glycosyl transferase (Group 1
C5O00_12440	ENOG4105CQB	FAD linked oxidase domain protein
C5O00_12445	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
C5O00_12460	ENOG4105D64	Mechanosensitive ion channel
C5O00_12465	ENOG4105D7Z	glutathione synthase
C5O00_12480	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
C5O00_12485	ENOG4105C98	muts2 protein
C5O00_12490	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
C5O00_12520	ENOG4105CPP	Dehydrogenase, E1 component
C5O00_12530	ENOG4105CDV	Ompa motb domain protein
C5O00_12545	ENOG41065KQ	synthase
C5O00_12550	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
C5O00_12560	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
C5O00_12565	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
C5O00_12570	ENOG4105EE5	Membrane protein terC
C5O00_12585	ENOG4105C6Z	Gluconate
C5O00_12590	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
C5O00_12595	ENOG4105CYF	SMP-30 gluconolaconase LRE domain protein
C5O00_12600	ENOG4108YYC	ycei family
C5O00_12625	ENOG4105C2C	drug resistance transporter, Bcr CflA
C5O00_12630	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
C5O00_12705	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C5O00_12710	ENOG4108I0Y	(ABC) transporter
C5O00_12715	ENOG4108UJV	acyl-CoA thioesterase i
C5O00_12720	ENOG4105EGS	Mechanosensitive ion channel
C5O00_12725	ENOG4105C9B	Cysteine desulfurase
C5O00_12730	ENOG4105DQ4	alcohol dehydrogenase
C5O00_12740	ENOG4105D05	Receptor
C5O00_12820	ENOG4105IIU	Aminopeptidase
C5O00_12835	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
C5O00_12845	ENOG4105W3H	MtN3 and saliva related transmembrane protein
C5O00_12915	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C5O00_12920	ENOG4105ER2	Ompa motb domain protein
C5O00_12930	ENOG4105CHR	reductase
C5O00_12945	ENOG4105VCH	membrane
C5O00_12950	ENOG4105CUY	Mechanosensitive ion channel
C5O00_12955	ENOG4108S4H	thioesterase Superfamily protein
C5O00_13000	ENOG4105D7N	magnesium and cobalt transport protein CorA
C5O00_13005	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
C5O00_13010	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
C5O00_13015	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
C5O00_13025	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
C5O00_13030	ENOG4105CIH	Imidazole acetol-phosphate transaminase
C5O00_13035	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
C5O00_13040	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
C5O00_13055	ENOG41080PD	NADH ubiquinone oxidoreductase 41 kD complex I subunit
C5O00_13070	ENOG4105CHR	reductase
C5O00_13075	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
C5O00_13085	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
C5O00_13090	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
C5O00_13095	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
C5O00_13100	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
C5O00_13105	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
C5O00_13110	ENOG4105DCI	Phosphohydrolase
C5O00_13115	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C5O00_13150	ENOG41062BK	proline dehydrogenase
C5O00_13155	ENOG4105D49	3-dehydroquinate synthase
C5O00_13170	ENOG4108VVK	transcriptional Regulator, AsnC
C5O00_13190	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
C5O00_13195	ENOG4105DF5	DNA topoisomerase IV, subunit A
C5O00_13200	ENOG4105DNX	Dna topoisomerase iv (Subunit b)
C5O00_13205	ENOG4105C3G	gtp-binding protein
C5O00_13220	ENOG4107XM9	(LipO)protein
C5O00_13265	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
C5O00_13270	ENOG4105D82	Glutamate dehydrogenase
C5O00_13275	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C5O00_13280	ENOG4105BZU	Histidine kinase
C5O00_13285	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
C5O00_13295	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
C5O00_13305	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
C5O00_13310	ENOG4108JQ1	Dehydrogenase
C5O00_13330	ENOG4105D05	Receptor
C5O00_13340	ENOG4105EUJ	GTP cyclohydrolase i
C5O00_13345	ENOG4107U7B	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
C5O00_13355	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
C5O00_13370	ENOG4105BZU	Histidine kinase
C5O00_13380	ENOG4105CD3	dihydroorotase
C5O00_13405	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
C5O00_13410	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
C5O00_13415	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
C5O00_13420	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
C5O00_13430	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C5O00_13435	ENOG4105CSM	endonuclease III
C5O00_13440	ENOG4105DU6	RNA polymerase
C5O00_13445	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
C5O00_13465	ENOG4107EF8	Glycosyl transferase (Group 1
C5O00_13490	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
C5O00_13505	ENOG41080WS	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
C5O00_13515	ENOG4105UYK	outer membrane protein a
C5O00_13520	ENOG4105KWI	UPF0339 protein
C5O00_13575	ENOG4105K89	arsenate reductase
C5O00_13585	ENOG4105C9Q	fumarate hydratase class II
C5O00_13595	ENOG4105CRE	cytochrome C
C5O00_13620	ENOG4105D9U	N-acetyltransferase
C5O00_13625	ENOG4108Z03	MAF-like protein
C5O00_13675	ENOG4105CHR	reductase
C5O00_13695	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
C5O00_13715	ENOG4105C9U	ATP-dependent DNA helicase RecQ
C5O00_13720	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
C5O00_13730	ENOG4108UJU	UPF0301 protein
C5O00_13735	ENOG4105F0I	Aminotransferase
C5O00_13930	ENOG4105KVH	Transcriptional regulator
C5O00_13935	ENOG4105NF4	modulator of drug activity
C5O00_14035	ENOG4105CUT	histidyl-tRNA synthetase
C5O00_14050	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
C5O00_14055	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
C5O00_14060	ENOG41080B9	Binds together with S18 to 16S ribosomal RNA (By similarity)
C5O00_14065	ENOG4108NEV	two component transcriptional regulator, LytTR family
C5O00_14070	ENOG4105C25	Primosomal protein n'
C5O00_14085	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
C5O00_14090	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
C5O00_14095	ENOG4105CHP	RNA polymerase
C5O00_14105	ENOG4105C26	Dehydrogenase
C5O00_14120	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
C5O00_14135	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
C5O00_14140	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
C5O00_14150	ENOG4107QTF	adenylosuccinate lyase
C5O00_14170	ENOG4105EMN	RNA polymerase sigma factor
C5O00_14190	ENOG4105EHG	Permease protein
C5O00_14195	ENOG4105E0A	ABC, transporter
C5O00_14200	ENOG4105CGY	Dna recombination protein
C5O00_14205	ENOG4105NAU	thioesterase Superfamily protein
C5O00_14240	ENOG4105VG0	50S ribosomal protein l34
C5O00_14285	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
C5O00_14290	ENOG4107QSI	ABC, transporter
C5O00_14310	ENOG41081WG	50s ribosomal protein l31
C5O00_14330	ENOG4105BZ1	(ABC) transporter
C5O00_14335	ENOG4105EMN	RNA polymerase sigma factor
C5O00_14370	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
C5O00_14375	ENOG4108IQE	Amp-dependent synthetase and ligase
C5O00_14385	ENOG41061ZR	Transcriptional regulator
C5O00_14400	ENOG4105CHU	acetyl-coa acetyltransferase
C5O00_14405	ENOG4105C1G	acyl-Coa dehydrogenase
C5O00_14420	ENOG4107VAM	peptidase, m28