locus-tag	class	description
Q31a_00090	COG0577	efflux transmembrane transporter activity
Q31a_00100	COG1136	(ABC) transporter
Q31a_00140	COG1643	Atp-dependent helicase
Q31a_00200	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Q31a_00220	COG0515	serine threonine protein kinase
Q31a_00260	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Q31a_00270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q31a_00290	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Q31a_00300	COG0668	transmembrane transport
Q31a_00320	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Q31a_00370	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Q31a_00400	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Q31a_00430	COG0736	holo-[acyl-carrier-protein] synthase activity
Q31a_00440	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Q31a_00450	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Q31a_00540	COG2815	serine threonine protein kinase
Q31a_00540	COG0515	serine threonine protein kinase
Q31a_00560	COG1442	glycosyl transferase family 8
Q31a_00560	COG1216	Glycosyl transferase, family 2
Q31a_00570	COG0644	oxidoreductase
Q31a_00640	COG0348	domain, Protein
Q31a_00650	COG2010	Cytochrome c
Q31a_00690	COG3119	arylsulfatase activity
Q31a_00750	COG0330	HflC and HflK could
Q31a_00790	COG1381	Involved in DNA repair and RecF pathway recombination
Q31a_00800	COG0745	RESPONSE REGULATOR receiver
Q31a_00810	COG0521	Mo-molybdopterin cofactor biosynthetic process
Q31a_00820	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Q31a_00830	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Q31a_00920	COG0443	Heat shock 70 kDa protein
Q31a_01010	COG1028	Short-chain dehydrogenase reductase Sdr
Q31a_01030	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Q31a_01040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q31a_01100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Q31a_01120	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Q31a_01150	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Q31a_01190	COG0714	Associated with various cellular activities
Q31a_01240	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Q31a_01250	COG3118	belongs to the thioredoxin family
Q31a_01280	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Q31a_01300	COG2738	Putative neutral zinc metallopeptidase
Q31a_01330	COG0515	serine threonine protein kinase
Q31a_01330	COG2815	serine threonine protein kinase
Q31a_01390	COG0588	phosphoglycerate mutase activity
Q31a_01410	COG2610	gluconate transmembrane transporter activity
Q31a_01430	COG0114	fumarate hydratase activity
Q31a_01440	COG0363	glucosamine-6-phosphate deaminase activity
Q31a_01490	COG3408	Glycogen debranching enzyme
Q31a_01490	COG3119	arylsulfatase activity
Q31a_01510	COG0515	serine threonine protein kinase
Q31a_01510	COG2815	serine threonine protein kinase
Q31a_01520	COG1595	DNA-templated transcription, initiation
Q31a_01540	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Q31a_01580	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Q31a_01590	COG2076	Multidrug Resistance protein
Q31a_01700	COG0463	Glycosyl transferase, family 2
Q31a_01710	COG3263	regulation of cellular component size
Q31a_01820	COG2755	lipolytic protein G-D-S-L family
Q31a_01840	COG3119	arylsulfatase activity
Q31a_01850	COG3119	arylsulfatase activity
Q31a_01920	COG0657	acetylesterase activity
Q31a_01920	COG2755	lipolytic protein G-D-S-L family
Q31a_02060	COG2204	response regulator
Q31a_02070	COG0328	RNA-DNA hybrid ribonuclease activity
Q31a_02080	COG0626	cystathionine gamma-synthase activity
Q31a_02090	COG0626	cystathionine gamma-synthase activity
Q31a_02190	COG4284	Utp--glucose-1-phosphate uridylyltransferase
Q31a_02210	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Q31a_02230	COG1716	ATPase activity
Q31a_02250	COG2154	pterin-4-alpha-carbinolamine dehydratase
Q31a_02260	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
Q31a_02280	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
Q31a_02290	COG0189	ligase activity
Q31a_02290	COG0569	domain protein
Q31a_02340	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Q31a_02370	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Q31a_02380	COG0803	Belongs to the bacterial solute-binding protein 9 family
Q31a_02390	COG1121	(ABC) transporter
Q31a_02400	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Q31a_02400	COG1321	iron dependent repressor
Q31a_02450	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
Q31a_02500	COG3973	AAA domain
Q31a_02530	COG0534	Mate efflux family protein
Q31a_02550	COG0515	serine threonine protein kinase
Q31a_02570	COG0463	Glycosyl transferase, family 2
Q31a_02650	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
Q31a_02670	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
Q31a_02690	COG4869	propanediol catabolic process
Q31a_02730	COG3119	arylsulfatase activity
Q31a_02780	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Q31a_02790	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Q31a_02870	COG0714	Associated with various cellular activities
Q31a_02880	COG2081	HI0933 family
Q31a_02890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Q31a_02910	COG0501	Belongs to the peptidase M48B family
Q31a_02920	COG1704	LemA family
Q31a_02940	COG3119	arylsulfatase activity
Q31a_02970	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Q31a_03030	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Q31a_03050	COG3437	response regulator, receiver
Q31a_03060	COG4999	Histidine kinase
Q31a_03060	COG3850	Histidine kinase
Q31a_03060	COG3437	response regulator, receiver
Q31a_03060	COG2205	protein histidine kinase activity
Q31a_03080	COG4771	TonB-dependent receptor
Q31a_03100	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Q31a_03110	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Q31a_03200	COG1215	transferase activity, transferring glycosyl groups
Q31a_03210	COG1305	Transglutaminase-like
Q31a_03250	COG0277	FAD linked oxidase domain protein
Q31a_03330	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
Q31a_03370	COG3119	arylsulfatase activity
Q31a_03380	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Q31a_03440	COG0569	domain protein
Q31a_03650	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Q31a_03680	COG2813	Specifically methylates the guanine in position
Q31a_03680	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Q31a_03750	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Q31a_03760	COG0577	efflux transmembrane transporter activity
Q31a_03760	COG1136	(ABC) transporter
Q31a_03770	COG1136	(ABC) transporter
Q31a_03870	COG0859	PFAM glycosyl transferase family 9
Q31a_03880	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Q31a_03900	COG3119	arylsulfatase activity
Q31a_03910	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Q31a_03920	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Q31a_03930	COG2346	COG2346, Truncated hemoglobins
Q31a_03940	COG0004	ammonium transporteR
Q31a_03950	COG4912	Dna alkylation repair
Q31a_03980	COG4447	cellulose binding
Q31a_03990	COG0189	ligase activity
Q31a_03990	COG0569	domain protein
Q31a_04010	COG2308	Evidence 4 Homologs of previously reported genes of
Q31a_04050	COG2308	Evidence 4 Homologs of previously reported genes of
Q31a_04050	COG2307	Protein conserved in bacteria
Q31a_04060	COG1305	Transglutaminase-like
Q31a_04090	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
Q31a_04090	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Q31a_04160	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
Q31a_04290	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Q31a_04320	COG2890	protein-(glutamine-N5) methyltransferase activity
Q31a_04340	COG0758	DNA mediated transformation
Q31a_04340	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Q31a_04350	COG1199	ATP-dependent helicase activity
Q31a_04360	COG2818	Glycosylase
Q31a_04370	COG2815	serine threonine protein kinase
Q31a_04370	COG0515	serine threonine protein kinase
Q31a_04390	COG2755	lipolytic protein G-D-S-L family
Q31a_04390	COG0657	acetylesterase activity
Q31a_04430	COG0187	DNA topoisomerase II activity
Q31a_04490	COG1229	Formylmethanofuran dehydrogenase subunit A
Q31a_04500	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
Q31a_04540	COG2226	methyltransferase
Q31a_04580	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Q31a_04590	COG3869	Catalyzes the specific phosphorylation of arginine residues in
Q31a_04640	COG0515	serine threonine protein kinase
Q31a_04640	COG2815	serine threonine protein kinase
Q31a_04700	COG2815	serine threonine protein kinase
Q31a_04700	COG0515	serine threonine protein kinase
Q31a_04710	COG0242	peptide deformylase activity
Q31a_04720	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Q31a_04730	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
Q31a_04750	COG2957	Belongs to the agmatine deiminase family
Q31a_04800	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Q31a_04810	COG1131	(ABC) transporter
Q31a_04830	COG0432	Pfam Uncharacterised protein family UPF0047
Q31a_04840	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Q31a_05110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q31a_05330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Q31a_05480	COG3547	Transposase (IS116 IS110 IS902 family)
Q31a_05510	COG4974	Belongs to the 'phage' integrase family
Q31a_05540	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
Q31a_05550	COG0529	Catalyzes the synthesis of activated sulfate
Q31a_05550	COG2895	sulfate adenylyltransferase (ATP) activity
Q31a_05560	COG0175	sulfate reduction
Q31a_05570	COG0357	Ribosomal RNA small subunit methyltransferase G
Q31a_05600	COG4232	protein-disulfide reductase activity
Q31a_05610	COG2813	Specifically methylates the guanine in position
Q31a_05640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Q31a_05660	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Q31a_05710	COG0367	asparagine synthase
Q31a_05720	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Q31a_05770	COG0793	Belongs to the peptidase S41A family
Q31a_05790	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Q31a_05840	COG1845	cytochrome c oxidase, subunit III
Q31a_05840	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Q31a_05850	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Q31a_05910	COG0437	4 iron, 4 sulfur cluster binding
Q31a_05970	COG1082	Xylose isomerase domain protein TIM barrel
Q31a_06030	COG2353	YceI-like domain
Q31a_06150	COG0515	serine threonine protein kinase
Q31a_06150	COG3266	domain, Protein
Q31a_06190	COG3408	Glycogen debranching enzyme
Q31a_06190	COG3119	arylsulfatase activity
Q31a_06240	COG3100	YcgL domain-containing protein
Q31a_06240	COG0561	phosphatase activity
Q31a_06280	COG0657	acetylesterase activity
Q31a_06290	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Q31a_06290	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Q31a_06350	COG0714	Associated with various cellular activities
Q31a_06370	COG0488	(ABC) transporter
Q31a_06430	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Q31a_06470	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Q31a_06550	COG0587	DNA-directed DNA polymerase activity
Q31a_06690	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Q31a_06700	COG0673	inositol 2-dehydrogenase activity
Q31a_06780	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Q31a_06780	COG4651	solute:proton antiporter activity
Q31a_06790	COG3119	arylsulfatase activity
Q31a_06930	COG1192	Involved in chromosome partitioning
Q31a_06960	COG1045	serine acetyltransferase
Q31a_07030	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Q31a_07040	COG0602	queuosine metabolic process
Q31a_07100	COG0066	3-isopropylmalate dehydratase activity
Q31a_07110	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Q31a_07130	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Q31a_07200	COG0673	inositol 2-dehydrogenase activity
Q31a_07220	COG0714	Associated with various cellular activities
Q31a_07250	COG0667	Aldo Keto reductase
Q31a_07280	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Q31a_07290	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Q31a_07370	COG0577	efflux transmembrane transporter activity
Q31a_07370	COG1136	(ABC) transporter
Q31a_07380	COG1136	(ABC) transporter
Q31a_07430	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Q31a_07440	COG0459	protein refolding
Q31a_07470	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
Q31a_07620	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Q31a_07780	COG3875	lactate racemase activity
Q31a_07790	COG1620	l-lactate permease
Q31a_07800	COG3119	arylsulfatase activity
Q31a_07810	COG3119	arylsulfatase activity
Q31a_07850	COG0714	Associated with various cellular activities
Q31a_08040	COG1609	Transcriptional regulator
Q31a_08070	COG0515	serine threonine protein kinase
Q31a_08070	COG2815	serine threonine protein kinase
Q31a_08130	COG3119	arylsulfatase activity
Q31a_08180	COG3119	arylsulfatase activity
Q31a_08440	COG3119	arylsulfatase activity
Q31a_08450	COG3119	arylsulfatase activity
Q31a_08480	COG1819	glycosyl
Q31a_08580	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
Q31a_08660	COG2815	serine threonine protein kinase
Q31a_08660	COG0515	serine threonine protein kinase
Q31a_08670	COG1595	DNA-templated transcription, initiation
Q31a_08730	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Q31a_08740	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Q31a_08750	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Q31a_08770	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Q31a_08820	COG0129	dihydroxy-acid dehydratase activity
Q31a_08850	COG0163	prenyltransferase activity
Q31a_08860	COG2226	methyltransferase
Q31a_08870	COG1556	Lactate utilization protein
Q31a_08880	COG1253	flavin adenine dinucleotide binding
Q31a_08910	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Q31a_08920	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Q31a_08930	COG0577	efflux transmembrane transporter activity
Q31a_08930	COG1136	(ABC) transporter
Q31a_08970	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Q31a_08980	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
Q31a_09040	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
Q31a_09070	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Q31a_09080	COG0203	ribosomal protein L17
Q31a_09090	COG0202	RNA polymerase activity
Q31a_09100	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Q31a_09110	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Q31a_09130	COG0201	protein transport
Q31a_09140	COG0200	Binds to the 23S rRNA
Q31a_09150	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Q31a_09170	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Q31a_09180	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Q31a_09190	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Q31a_09200	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Q31a_09210	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Q31a_09220	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Q31a_09230	COG0255	Belongs to the universal ribosomal protein uL29 family
Q31a_09240	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Q31a_09250	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Q31a_09260	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Q31a_09270	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Q31a_09280	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Q31a_09290	COG0089	rRNA binding
Q31a_09300	COG0088	Forms part of the polypeptide exit tunnel
Q31a_09310	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Q31a_09320	COG0051	transcription antitermination factor activity, RNA binding
Q31a_09360	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Q31a_09380	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Q31a_09400	COG0107	imidazoleglycerol-phosphate synthase activity
Q31a_09420	COG2885	chlorophyll binding
Q31a_09460	COG0811	peptide transport
Q31a_09480	COG0180	Tryptophanyl-tRNA synthetase
Q31a_09530	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Q31a_09540	COG1758	RNA polymerase activity
Q31a_09550	COG0194	GDP metabolic process
Q31a_09560	COG1561	YicC-like family, N-terminal region
Q31a_09580	COG0149	triose-phosphate isomerase activity
Q31a_09620	COG3119	arylsulfatase activity
Q31a_09630	COG3008	intermembrane lipid transfer
Q31a_09640	COG2995	paraquat-inducible protein a
Q31a_09660	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Q31a_09690	COG0156	8-amino-7-oxononanoate synthase activity
Q31a_09710	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Q31a_09840	COG3320	Male sterility
Q31a_09840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Q31a_09860	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
Q31a_09860	COG3264	Mechanosensitive ion channel
Q31a_09990	COG2384	SAM-dependent methyltransferase
Q31a_10030	COG0318	PFAM AMP-dependent synthetase and ligase
Q31a_10030	COG0204	Acyl-transferase
Q31a_10040	COG3119	arylsulfatase activity
Q31a_10070	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
Q31a_10090	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
Q31a_10110	COG0577	efflux transmembrane transporter activity
Q31a_10110	COG1136	(ABC) transporter
Q31a_10120	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Q31a_10230	COG3119	arylsulfatase activity
Q31a_10240	COG0560	Phosphoserine phosphatase
Q31a_10240	COG3830	Belongs to the UPF0237 family
Q31a_10250	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Q31a_10270	COG1872	DUF167
Q31a_10280	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Q31a_10330	COG4650	regulator
Q31a_10350	COG0430	RNA-3'-phosphate cyclase activity
Q31a_10390	COG0024	Methionine aminopeptidase
Q31a_10400	COG1671	Belongs to the UPF0178 family
Q31a_10420	COG0513	Belongs to the DEAD box helicase family
Q31a_10430	COG1278	Cold shock
Q31a_10490	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Q31a_10540	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Q31a_10550	COG0081	regulation of translation
Q31a_10560	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Q31a_10570	COG0222	ribosome binding
Q31a_10580	COG0248	Ppx GppA phosphatase
Q31a_10620	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Q31a_10730	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Q31a_10760	COG2877	3-deoxy-8-phosphooctulonate synthase activity
Q31a_10780	COG1970	mechanosensitive ion channel activity
Q31a_10790	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Q31a_10800	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Q31a_10860	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Q31a_10890	COG0556	nucleotide-excision repair
Q31a_10900	COG0515	serine threonine protein kinase
Q31a_10900	COG2815	serine threonine protein kinase
Q31a_10920	COG0564	pseudouridine synthase activity
Q31a_11040	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Q31a_11050	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Q31a_11070	COG0724	RNA recognition motif
Q31a_11150	COG0537	adenosine 5'-monophosphoramidase activity
Q31a_11210	COG0564	pseudouridine synthase activity
Q31a_11220	COG1966	Carbon starvation protein
Q31a_11230	COG1301	dicarboxylic acid transport
Q31a_11260	COG1450	Type ii and iii secretion system protein
Q31a_11310	COG4999	Histidine kinase
Q31a_11310	COG3850	Histidine kinase
Q31a_11310	COG3437	response regulator, receiver
Q31a_11310	COG2205	protein histidine kinase activity
Q31a_11370	COG3119	arylsulfatase activity
Q31a_11380	COG1012	belongs to the aldehyde dehydrogenase family
Q31a_11430	COG0006	proline dipeptidase activity
Q31a_11440	COG0519	Catalyzes the synthesis of GMP from XMP
Q31a_11440	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Q31a_11450	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Q31a_11510	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
Q31a_11530	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
Q31a_11550	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Q31a_11560	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
Q31a_11840	COG3547	Transposase (IS116 IS110 IS902 family)
Q31a_11920	COG4974	Belongs to the 'phage' integrase family
Q31a_12280	COG2186	Transcriptional regulator
Q31a_12290	COG4221	oxidoreductase activity
Q31a_12350	COG0653	protein targeting
Q31a_12360	COG1519	Transferase
Q31a_12380	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Q31a_12390	COG0085	RNA polymerase activity
Q31a_12400	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Q31a_12420	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Q31a_12430	COG1459	type II secretion system
Q31a_12520	COG0205	6-phosphofructokinase activity
Q31a_12530	COG0439	Biotin carboxylase
Q31a_12540	COG0511	ligase activity, forming carbon-carbon bonds
Q31a_12550	COG0006	proline dipeptidase activity
Q31a_12610	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Q31a_12610	COG1754	DNA topoisomerase type I activity
Q31a_12660	COG0297	glycogen (starch) synthase activity
Q31a_12760	COG4970	Tfp pilus assembly protein FimT
Q31a_12780	COG1459	type II secretion system
Q31a_12790	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Q31a_12890	COG3119	arylsulfatase activity
Q31a_12900	COG3119	arylsulfatase activity
Q31a_12980	COG0488	(ABC) transporter
Q31a_13030	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Q31a_13050	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Q31a_13070	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Q31a_13100	COG0300	oxidoreductase activity
Q31a_13180	COG0488	(ABC) transporter
Q31a_13340	COG0247	lactate metabolic process
Q31a_13360	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Q31a_13370	COG0049	tRNA binding
Q31a_13380	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Q31a_13400	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Q31a_13420	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Q31a_13430	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Q31a_13440	COG0358	DNA primase activity
Q31a_13460	COG0517	IMP dehydrogenase activity
Q31a_13460	COG1227	inorganic diphosphatase activity
Q31a_13480	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Q31a_13650	COG1621	beta-fructofuranosidase activity
Q31a_13660	COG0589	response to stress
Q31a_13670	COG0589	response to stress
Q31a_13680	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Q31a_13720	COG0471	metal ion transport
Q31a_13720	COG0490	domain, Protein
Q31a_13740	COG4974	Belongs to the 'phage' integrase family
Q31a_13960	COG3415	Transposase
Q31a_13960	COG2801	Transposase and inactivated derivatives
Q31a_13990	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Q31a_14050	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Q31a_14090	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Q31a_14100	COG2197	response regulator
Q31a_14130	COG3119	arylsulfatase activity
Q31a_14180	COG1160	GTP binding
Q31a_14280	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Q31a_14290	COG1185	polyribonucleotide nucleotidyltransferase activity
Q31a_14330	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Q31a_14340	COG0515	serine threonine protein kinase
Q31a_14340	COG2815	serine threonine protein kinase
Q31a_14390	COG1285	pathogenesis
Q31a_14410	COG3237	CsbD-like
Q31a_14430	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Q31a_14440	COG1449	Belongs to the glycosyl hydrolase 57 family
Q31a_14460	COG4993	Dehydrogenase
Q31a_14510	COG1404	Belongs to the peptidase S8 family
Q31a_14520	COG2205	protein histidine kinase activity
Q31a_14520	COG4999	Histidine kinase
Q31a_14520	COG3850	Histidine kinase
Q31a_14520	COG3437	response regulator, receiver
Q31a_14550	COG3119	arylsulfatase activity
Q31a_14570	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
Q31a_14580	COG0823	Involved in the tonB-independent uptake of proteins
Q31a_14580	COG1506	peptidase
Q31a_14590	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Q31a_14780	COG0515	serine threonine protein kinase
Q31a_14780	COG2815	serine threonine protein kinase
Q31a_14970	COG0714	Associated with various cellular activities
Q31a_15140	COG2815	serine threonine protein kinase
Q31a_15140	COG0515	serine threonine protein kinase
Q31a_15180	COG0515	serine threonine protein kinase
Q31a_15180	COG2815	serine threonine protein kinase
Q31a_15270	COG2204	response regulator
Q31a_15280	COG4191	Histidine kinase
Q31a_15290	COG0584	glycerophosphoryl diester phosphodiesterase
Q31a_15320	COG0668	transmembrane transport
Q31a_15350	COG0702	epimerase
Q31a_15370	COG3119	arylsulfatase activity
Q31a_15390	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
Q31a_15400	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Q31a_15420	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Q31a_15470	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Q31a_15490	COG1028	Short-chain dehydrogenase reductase Sdr
Q31a_15500	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Q31a_15520	COG3119	arylsulfatase activity
Q31a_15580	COG3119	arylsulfatase activity
Q31a_15640	COG1725	Transcriptional regulator
Q31a_15650	COG1131	(ABC) transporter
Q31a_15680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Q31a_15690	COG1774	PSP1 C-terminal conserved region
Q31a_15730	COG2211	Major facilitator Superfamily
Q31a_15810	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Q31a_15820	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Q31a_15830	COG0604	alcohol dehydrogenase
Q31a_15830	COG3321	synthase
Q31a_15830	COG1028	Short-chain dehydrogenase reductase Sdr
Q31a_15870	COG0129	dihydroxy-acid dehydratase activity
Q31a_15940	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Q31a_15950	COG0322	excinuclease ABC activity
Q31a_16040	COG2706	6-phosphogluconolactonase activity
Q31a_16060	COG3119	arylsulfatase activity
Q31a_16070	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Q31a_16080	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Q31a_16150	COG0505	Belongs to the CarA family
Q31a_16160	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Q31a_16170	COG3119	arylsulfatase activity
Q31a_16190	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Q31a_16270	COG0750	zinc metalloprotease
Q31a_16280	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Q31a_16290	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Q31a_16310	COG0515	serine threonine protein kinase
Q31a_16310	COG2815	serine threonine protein kinase
Q31a_16340	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q31a_16340	COG5549	protein import
Q31a_16420	COG1937	Protein conserved in bacteria
Q31a_16450	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Q31a_16490	COG1595	DNA-templated transcription, initiation
Q31a_16620	COG4806	L-rhamnose isomerase
Q31a_16800	COG2226	methyltransferase
Q31a_16910	COG2770	Histidine kinase
Q31a_16910	COG3437	response regulator, receiver
Q31a_16940	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Q31a_17000	COG0463	Glycosyl transferase, family 2
Q31a_17020	COG2226	methyltransferase
Q31a_17050	COG0306	phosphate transporter
Q31a_17060	COG1216	Glycosyl transferase, family 2
Q31a_17080	COG4941	Belongs to the sigma-70 factor family
Q31a_17100	COG0640	Transcriptional regulator
Q31a_17140	COG3795	YCII-related domain
Q31a_17160	COG3795	YCII-related domain
Q31a_17560	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
Q31a_17590	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Q31a_17610	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Q31a_17650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q31a_17670	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Q31a_17760	COG1063	alcohol dehydrogenase
Q31a_17770	COG1082	Xylose isomerase domain protein TIM barrel
Q31a_17790	COG1132	(ABC) transporter
Q31a_17810	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Q31a_17890	COG0500	methyltransferase
Q31a_17930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Q31a_17930	COG1522	sequence-specific DNA binding
Q31a_17940	COG0438	transferase activity, transferring glycosyl groups
Q31a_17990	COG0667	Aldo Keto reductase
Q31a_18020	COG0347	Belongs to the P(II) protein family
Q31a_18100	COG1858	cytochrome C peroxidase
Q31a_18170	COG3119	arylsulfatase activity
Q31a_18220	COG3119	arylsulfatase activity
Q31a_18280	COG3119	arylsulfatase activity
Q31a_18350	COG0463	Glycosyl transferase, family 2
Q31a_18440	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Q31a_18440	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Q31a_18450	COG3142	Participates in the control of copper homeostasis
Q31a_18460	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Q31a_18480	COG2321	neutral zinc metallopeptidase
Q31a_18500	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Q31a_18510	COG2084	Dehydrogenase
Q31a_18560	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Q31a_18580	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Q31a_18580	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Q31a_18610	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Q31a_19130	COG0515	serine threonine protein kinase
Q31a_19130	COG0457	Tetratricopeptide repeat
Q31a_19150	COG2094	Belongs to the DNA glycosylase MPG family
Q31a_19190	COG1573	uracil-dna glycosylase
Q31a_19200	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Q31a_19380	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Q31a_19380	COG1042	CoA-binding domain protein
Q31a_19380	COG0045	succinate-CoA ligase (ADP-forming) activity
Q31a_19420	COG0588	phosphoglycerate mutase activity
Q31a_19500	COG3250	beta-galactosidase activity
Q31a_19570	COG2226	methyltransferase
Q31a_19660	COG0673	inositol 2-dehydrogenase activity
Q31a_19710	COG1064	alcohol dehydrogenase
Q31a_19780	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Q31a_19810	COG0528	UMP kinase activity
Q31a_19820	COG0233	cytoplasmic translational termination
Q31a_19850	COG0517	IMP dehydrogenase activity
Q31a_19850	COG1994	Peptidase M50
Q31a_19910	COG0436	Aminotransferase
Q31a_19930	COG1137	ATPase activity
Q31a_19940	COG0515	serine threonine protein kinase
Q31a_19940	COG2815	serine threonine protein kinase
Q31a_19960	COG2771	luxR family
Q31a_19960	COG2200	EAL domain
Q31a_20270	COG3119	arylsulfatase activity
Q31a_20390	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Q31a_20410	COG0826	peptidase U32
Q31a_20490	COG2022	thiamine diphosphate biosynthetic process
Q31a_20540	COG1643	Atp-dependent helicase
Q31a_20560	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Q31a_20560	COG0321	lipoyl(octanoyl) transferase activity
Q31a_20580	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Q31a_20580	COG0617	tRNA 3'-terminal CCA addition
Q31a_20580	COG0517	IMP dehydrogenase activity
Q31a_20610	COG3540	Alkaline phosphatase
Q31a_20620	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Q31a_20690	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Q31a_20700	COG1335	isochorismatase
Q31a_20720	COG1091	dTDP-4-dehydrorhamnose reductase activity
Q31a_20730	COG2382	esterase
Q31a_20770	COG1040	competence protein
Q31a_20900	COG2942	2-epimerase
Q31a_20910	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Q31a_20920	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Q31a_21000	COG0047	phosphoribosylformylglycinamidine synthase activity
Q31a_21030	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Q31a_21040	COG1250	3-hydroxyacyl-CoA dehydrogenase
Q31a_21110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q31a_21160	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
Q31a_21180	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Q31a_21190	COG1509	lysine 2,3-aminomutase activity
Q31a_21200	COG0285	dihydrofolate synthase activity
Q31a_21220	COG1131	(ABC) transporter
Q31a_21290	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Q31a_21380	COG0473	3-isopropylmalate dehydrogenase activity
Q31a_21550	COG1028	Short-chain dehydrogenase reductase Sdr
Q31a_21860	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Q31a_21870	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Q31a_21890	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
Q31a_21920	COG0134	indole-3-glycerol-phosphate synthase activity
Q31a_21930	COG0138	bifunctional purine biosynthesis protein purh
Q31a_21940	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Q31a_21960	COG1131	(ABC) transporter
Q31a_22030	COG0142	geranyltranstransferase activity
Q31a_22070	COG3119	arylsulfatase activity
Q31a_22080	COG4948	Mandelate Racemase Muconate Lactonizing
Q31a_22170	COG1028	Short-chain dehydrogenase reductase Sdr
Q31a_22200	COG0714	Associated with various cellular activities
Q31a_22210	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
Q31a_22220	COG0017	Asparaginyl-tRNA synthetase
Q31a_22230	COG0492	ferredoxin-NADP+ reductase activity
Q31a_22240	COG0471	metal ion transport
Q31a_22300	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Q31a_22320	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Q31a_22440	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
Q31a_22480	COG0084	hydrolase, TatD family'
Q31a_22490	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Q31a_22500	COG1448	Aminotransferase
Q31a_22510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Q31a_22510	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Q31a_22570	COG0037	tRNA processing
Q31a_22590	COG0343	queuine tRNA-ribosyltransferase activity
Q31a_22600	COG0202	RNA polymerase activity
Q31a_22620	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Q31a_22700	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Q31a_22720	COG0247	lactate metabolic process
Q31a_22760	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Q31a_22780	COG1070	Carbohydrate kinase
Q31a_22820	COG0135	phosphoribosylanthranilate isomerase activity
Q31a_22890	COG0189	ligase activity
Q31a_22890	COG4067	protein conserved in archaea
Q31a_22900	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Q31a_22920	COG0730	response to heat
Q31a_22930	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Q31a_22940	COG1678	Uncharacterized ACR, COG1678
Q31a_22960	COG0318	PFAM AMP-dependent synthetase and ligase
Q31a_22970	COG0673	inositol 2-dehydrogenase activity
Q31a_22990	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Q31a_23000	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Q31a_23020	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Q31a_23060	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Q31a_23100	COG0643	Histidine kinase
Q31a_23100	COG0784	Response regulator, receiver
Q31a_23100	COG2198	Histidine kinase
Q31a_23110	COG0835	chemotaxis
Q31a_23120	COG2201	protein-glutamate methylesterase activity
Q31a_23140	COG1475	DNA binding
Q31a_23150	COG1192	Involved in chromosome partitioning
Q31a_23220	COG0488	(ABC) transporter
Q31a_23280	COG0322	excinuclease ABC activity
Q31a_23370	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Q31a_23410	COG1139	Iron-sulfur cluster binding protein
Q31a_23420	COG0018	arginyl-trna synthetase
Q31a_23430	COG0799	negative regulation of ribosome biogenesis
Q31a_23440	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Q31a_23460	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Q31a_23560	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
Q31a_23580	COG1408	metallophosphoesterase
Q31a_23650	COG0515	serine threonine protein kinase
Q31a_23650	COG2815	serine threonine protein kinase
Q31a_23670	COG0076	glutamate decarboxylase activity
Q31a_23700	COG2755	lipolytic protein G-D-S-L family
Q31a_23700	COG0657	acetylesterase activity
Q31a_23720	COG1546	Belongs to the CinA family
Q31a_23720	COG1058	Belongs to the CinA family
Q31a_23750	COG0577	efflux transmembrane transporter activity
Q31a_23750	COG1136	(ABC) transporter
Q31a_23760	COG0577	efflux transmembrane transporter activity
Q31a_23810	COG0545	Peptidyl-prolyl cis-trans isomerase
Q31a_23890	COG0529	Catalyzes the synthesis of activated sulfate
Q31a_23930	COG1530	ribonuclease E activity
Q31a_23960	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Q31a_23990	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Q31a_24060	COG1070	Carbohydrate kinase
Q31a_24070	COG2205	protein histidine kinase activity
Q31a_24090	COG4864	UPF0365 protein
Q31a_24110	COG2326	polyphosphate kinase activity
Q31a_24140	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Q31a_24140	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Q31a_24160	COG1131	(ABC) transporter
Q31a_24180	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Q31a_24200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q31a_24280	COG0673	inositol 2-dehydrogenase activity
Q31a_24330	COG1692	metallophosphoesterase
Q31a_24340	COG1418	mRNA catabolic process
Q31a_24400	COG3264	Mechanosensitive ion channel
Q31a_24400	COG1511	domain protein
Q31a_24410	COG0598	Magnesium transport protein CorA
Q31a_24480	COG4251	negative regulation of phosphorylation
Q31a_24490	COG0784	Response regulator, receiver
Q31a_24500	COG0517	IMP dehydrogenase activity
Q31a_24500	COG0516	GMP reductase activity
Q31a_24570	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Q31a_24600	COG1131	(ABC) transporter
Q31a_24630	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Q31a_24680	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Q31a_24690	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Q31a_24700	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Q31a_24710	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Q31a_24720	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Q31a_24730	COG0483	inositol monophosphate 1-phosphatase activity
Q31a_24740	COG0656	L-ascorbic acid biosynthetic process
Q31a_24850	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Q31a_24920	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Q31a_24990	COG3119	arylsulfatase activity
Q31a_25090	COG3119	arylsulfatase activity
Q31a_25150	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Q31a_25170	COG1566	PFAM secretion protein HlyD family protein
Q31a_25230	COG2909	trisaccharide binding
Q31a_25300	COG2815	serine threonine protein kinase
Q31a_25300	COG0515	serine threonine protein kinase
Q31a_25330	COG0515	serine threonine protein kinase
Q31a_25330	COG2815	serine threonine protein kinase
Q31a_25370	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Q31a_25380	COG1028	Short-chain dehydrogenase reductase Sdr
Q31a_25400	COG2814	Major facilitator Superfamily
Q31a_25410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Q31a_25430	COG0512	Glutamine amidotransferase of anthranilate synthase
Q31a_25440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Q31a_25460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q31a_25470	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Q31a_25500	COG1331	Highly conserved protein containing a thioredoxin domain
Q31a_25510	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Q31a_25530	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Q31a_25550	COG1595	DNA-templated transcription, initiation
Q31a_25570	COG2373	Large extracellular alpha-helical protein
Q31a_25640	COG3781	membrane
Q31a_25690	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Q31a_25700	COG1104	cysteine desulfurase activity
Q31a_25710	COG0628	permease
Q31a_25730	COG3119	arylsulfatase activity
Q31a_25740	COG0840	transmembrane signaling receptor activity
Q31a_25810	COG0657	acetylesterase activity
Q31a_25820	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Q31a_25830	COG0052	Belongs to the universal ribosomal protein uS2 family
Q31a_25920	COG0009	L-threonylcarbamoyladenylate synthase
Q31a_25930	COG0237	dephospho-CoA kinase activity
Q31a_25960	COG1902	pentaerythritol trinitrate reductase activity
Q31a_26020	COG0573	inorganic phosphate transmembrane transporter activity
Q31a_26030	COG0581	inorganic phosphate transmembrane transporter activity
Q31a_26040	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Q31a_26100	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Q31a_26220	COG2936	dipeptidyl-peptidase activity
Q31a_26250	COG2304	oxidoreductase activity
Q31a_26260	COG2304	oxidoreductase activity
Q31a_26290	COG0714	Associated with various cellular activities
Q31a_26310	COG1505	serine-type exopeptidase activity
Q31a_26340	COG0328	RNA-DNA hybrid ribonuclease activity
Q31a_26350	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Q31a_26370	COG2382	esterase
Q31a_26390	COG1674	ftsk spoiiie
Q31a_26390	COG4980	gas vesicle protein
Q31a_26400	COG4589	Belongs to the CDS family
Q31a_26420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Q31a_26550	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Q31a_26560	COG0527	aspartate kinase activity
Q31a_26570	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
Q31a_26650	COG0714	Associated with various cellular activities
Q31a_26750	COG0495	leucyl-tRNA aminoacylation
Q31a_26760	COG1216	Glycosyl transferase, family 2
Q31a_26770	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Q31a_26780	COG0028	Belongs to the TPP enzyme family
Q31a_26800	COG0494	nUDIX hydrolase
Q31a_26850	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
Q31a_26880	COG1621	beta-fructofuranosidase activity
Q31a_27150	COG4695	Portal protein
Q31a_27160	COG1802	Transcriptional regulator
Q31a_27160	COG4626	Terminase
Q31a_27320	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Q31a_27390	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Q31a_27420	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Q31a_27450	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Q31a_27450	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Q31a_27490	COG4566	intracellular signal transduction
Q31a_27510	COG2183	response to ionizing radiation
Q31a_27510	COG0539	negative regulation of cytoplasmic translation
Q31a_27520	COG0698	ribose 5-phosphate isomerase
Q31a_27530	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Q31a_27540	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Q31a_27550	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Q31a_27620	COG0653	protein targeting
Q31a_27670	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Q31a_27710	COG3273	potassium ion transport
Q31a_27710	COG0471	metal ion transport
Q31a_27720	COG0579	oxidoreductase
Q31a_27730	COG0657	acetylesterase activity
Q31a_27740	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Q31a_27750	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Q31a_27770	COG3253	May function as heme-dependent peroxidase
Q31a_27790	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Q31a_27810	COG0584	glycerophosphoryl diester phosphodiesterase
Q31a_27860	COG0514	ATP-dependent DNA helicase (RecQ)
Q31a_27870	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
Q31a_27880	COG0659	secondary active sulfate transmembrane transporter activity
Q31a_27900	COG1252	NADH dehydrogenase
Q31a_27910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q31a_27920	COG3104	oligopeptide transport
Q31a_27930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Q31a_27940	COG3938	Belongs to the proline racemase family
Q31a_27970	COG0784	Response regulator, receiver
Q31a_27970	COG5002	protein histidine kinase activity
Q31a_27970	COG2205	protein histidine kinase activity
Q31a_28030	COG3494	Protein of unknown function (DUF1009)
Q31a_28040	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Q31a_28060	COG0268	Binds directly to 16S ribosomal RNA
Q31a_28080	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Q31a_28140	COG3258	Cytochrome c
Q31a_28160	COG3119	arylsulfatase activity
Q31a_28200	COG1595	DNA-templated transcription, initiation
Q31a_28230	COG3852	Histidine kinase
Q31a_28250	COG3002	Belongs to the UPF0753 family
Q31a_28260	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Q31a_28270	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Q31a_28280	COG0659	secondary active sulfate transmembrane transporter activity
Q31a_28330	COG0598	Magnesium transport protein CorA
Q31a_28610	COG0604	alcohol dehydrogenase
Q31a_28610	COG3321	synthase
Q31a_28660	COG3119	arylsulfatase activity
Q31a_28670	COG4566	intracellular signal transduction
Q31a_28680	COG4566	intracellular signal transduction
Q31a_28690	COG4191	Histidine kinase
Q31a_28710	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
Q31a_28730	COG3119	arylsulfatase activity
Q31a_28730	COG3408	Glycogen debranching enzyme
Q31a_28820	COG1054	Belongs to the UPF0176 family
Q31a_28830	COG0302	gtp cyclohydrolase
Q31a_28860	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Q31a_28890	COG1233	COG1233 Phytoene dehydrogenase and related
Q31a_28920	COG2971	BadF BadG BcrA BcrD
Q31a_28930	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
Q31a_28950	COG3876	Protein conserved in bacteria
Q31a_28960	COG3876	Protein conserved in bacteria
Q31a_28970	COG0657	acetylesterase activity
Q31a_28980	COG3119	arylsulfatase activity
Q31a_29010	COG4974	Belongs to the 'phage' integrase family
Q31a_29040	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Q31a_29040	COG3153	acetyltransferase
Q31a_29050	COG1166	arginine decarboxylase activity
Q31a_29060	COG3119	arylsulfatase activity
Q31a_29080	COG1301	dicarboxylic acid transport
Q31a_29090	COG0673	inositol 2-dehydrogenase activity
Q31a_29190	COG0179	Fumarylacetoacetate (FAA) hydrolase
Q31a_29210	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Q31a_29240	COG0753	catalase activity
Q31a_29250	COG3685	Protein conserved in bacteria
Q31a_29290	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Q31a_29340	COG1017	nitric oxide dioxygenase activity
Q31a_29340	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Q31a_29370	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Q31a_29390	COG2912	Transglutaminase-like superfamily
Q31a_29430	COG1104	cysteine desulfurase activity
Q31a_29510	COG0419	ATPase involved in DNA repair
Q31a_29540	COG1484	DNA-dependent DNA replication
Q31a_29600	COG2755	lipolytic protein G-D-S-L family
Q31a_29660	COG2205	protein histidine kinase activity
Q31a_29740	COG3119	arylsulfatase activity
Q31a_29790	COG1595	DNA-templated transcription, initiation
Q31a_29940	COG2183	response to ionizing radiation
Q31a_30020	COG0515	serine threonine protein kinase
Q31a_30020	COG2815	serine threonine protein kinase
Q31a_30050	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Q31a_30090	COG0347	Belongs to the P(II) protein family
Q31a_30130	COG1242	4 iron, 4 sulfur cluster binding
Q31a_30140	COG1716	ATPase activity
Q31a_30200	COG0626	cystathionine gamma-synthase activity
Q31a_30220	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
Q31a_30260	COG3119	arylsulfatase activity
Q31a_30270	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Q31a_30280	COG0438	transferase activity, transferring glycosyl groups
Q31a_30360	COG0438	transferase activity, transferring glycosyl groups
Q31a_30400	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Q31a_30460	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Q31a_30490	COG3119	arylsulfatase activity
Q31a_30500	COG3119	arylsulfatase activity
Q31a_30510	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Q31a_30520	COG1418	mRNA catabolic process
Q31a_30530	COG3119	arylsulfatase activity
Q31a_30540	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Q31a_30590	COG2151	metal-sulfur cluster biosynthetic enzyme
Q31a_30610	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
Q31a_30620	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
Q31a_30630	COG0667	Aldo Keto reductase
Q31a_30650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Q31a_30660	COG1063	alcohol dehydrogenase
Q31a_30690	COG3344	reverse transcriptase
Q31a_30710	COG2204	response regulator
Q31a_30740	COG0784	Response regulator, receiver
Q31a_30750	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Q31a_30760	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Q31a_30770	COG2382	esterase
Q31a_30830	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Q31a_30850	COG2234	aminopeptidase activity
Q31a_30880	COG0012	GTP binding
Q31a_30890	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Q31a_31060	COG0366	Alpha amylase catalytic
Q31a_31070	COG1215	transferase activity, transferring glycosyl groups
Q31a_31120	COG0842	Transport permease protein
Q31a_31130	COG0842	Transport permease protein
Q31a_31130	COG1129	ABC transporter
Q31a_31140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Q31a_31150	COG0204	Acyl-transferase
Q31a_31150	COG0318	PFAM AMP-dependent synthetase and ligase
Q31a_31170	COG0657	acetylesterase activity
Q31a_31300	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
Q31a_31390	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Q31a_31400	COG0140	phosphoribosyl-ATP diphosphatase activity
Q31a_31410	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Q31a_31430	COG2088	sporulation resulting in formation of a cellular spore
Q31a_31440	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Q31a_31450	COG0105	UTP biosynthetic process
Q31a_31470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Q31a_31480	COG0577	efflux transmembrane transporter activity
Q31a_31480	COG1136	(ABC) transporter
Q31a_31490	COG0577	efflux transmembrane transporter activity
Q31a_31490	COG1136	(ABC) transporter
Q31a_31680	COG5001	Diguanylate cyclase
Q31a_31680	COG3300	MHYT domain
Q31a_31700	COG1012	belongs to the aldehyde dehydrogenase family
Q31a_31810	COG1115	amino acid carrier protein
Q31a_31830	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Q31a_31880	COG3118	belongs to the thioredoxin family
Q31a_31920	COG4948	Mandelate Racemase Muconate Lactonizing
Q31a_32020	COG3119	arylsulfatase activity
Q31a_32140	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Q31a_32170	COG0714	Associated with various cellular activities
Q31a_32250	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Q31a_32270	COG0573	inorganic phosphate transmembrane transporter activity
Q31a_32280	COG0581	inorganic phosphate transmembrane transporter activity
Q31a_32300	COG2226	methyltransferase
Q31a_32310	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
Q31a_32320	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Q31a_32330	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Q31a_32370	COG0481	GTPase activity
Q31a_32380	COG1940	carbohydrate kinase activity
Q31a_32550	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
Q31a_32570	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
Q31a_32640	COG0644	oxidoreductase
Q31a_32670	COG3377	Domain of unknown function (DUF1805)
Q31a_32790	COG0606	chelatase, subunit chli
Q31a_32810	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Q31a_32820	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Q31a_32840	COG0509	glycine decarboxylation via glycine cleavage system
Q31a_32850	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Q31a_32870	COG1454	alcohol dehydrogenase
Q31a_32980	COG1845	cytochrome c oxidase, subunit III
Q31a_33000	COG2824	Alkylphosphonate utilization operon protein PhnA
Q31a_33060	COG0277	FAD linked oxidase domain protein
Q31a_33070	COG1297	OPT oligopeptide transporter protein
Q31a_33110	COG0318	PFAM AMP-dependent synthetase and ligase
Q31a_33130	COG0515	serine threonine protein kinase
Q31a_33130	COG2815	serine threonine protein kinase
Q31a_33140	COG1858	cytochrome C peroxidase
Q31a_33200	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Q31a_33330	COG1668	transmembrane transport
Q31a_33340	COG4555	ABC transporter
Q31a_33400	COG3119	arylsulfatase activity
Q31a_33430	COG0793	Belongs to the peptidase S41A family
Q31a_33450	COG3119	arylsulfatase activity
Q31a_33480	COG0187	DNA topoisomerase II activity
Q31a_33500	COG3239	Fatty acid desaturase
Q31a_33530	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Q31a_33540	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Q31a_33550	COG3119	arylsulfatase activity
Q31a_33570	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Q31a_33580	COG1480	7TM receptor with intracellular HD hydrolase
Q31a_33590	COG1702	phosphate starvation-inducible protein PhoH
Q31a_33600	COG4589	Belongs to the CDS family
Q31a_33610	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Q31a_33620	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Q31a_33640	COG4956	integral membrane protein (PIN domain superfamily)
Q31a_33660	COG3437	response regulator, receiver
Q31a_33740	COG1706	bacterial-type flagellum-dependent cell motility
Q31a_33750	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
Q31a_33770	COG4786	Flagellar basal body rod
Q31a_33780	COG4786	Flagellar basal body rod
Q31a_33800	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Q31a_33810	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Q31a_33860	COG0420	3'-5' exonuclease activity
Q31a_33930	COG3437	response regulator, receiver
Q31a_33930	COG3850	Histidine kinase
Q31a_33930	COG4999	Histidine kinase
Q31a_33930	COG2205	protein histidine kinase activity
Q31a_33960	COG3119	arylsulfatase activity
Q31a_34040	COG2255	four-way junction helicase activity
Q31a_34060	COG0438	transferase activity, transferring glycosyl groups
Q31a_34100	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Q31a_34110	COG2030	dehydratase
Q31a_34160	COG2814	Major facilitator Superfamily
Q31a_34180	COG4555	ABC transporter
Q31a_34250	COG0673	inositol 2-dehydrogenase activity
Q31a_34260	COG3189	MarR family transcriptional regulator
Q31a_34270	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Q31a_34320	COG3119	arylsulfatase activity
Q31a_34340	COG1446	asparaginase
Q31a_34430	COG3119	arylsulfatase activity
Q31a_34440	COG3119	arylsulfatase activity
Q31a_34450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Q31a_34460	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Q31a_34720	COG0788	formyltetrahydrofolate deformylase activity
Q31a_34740	COG0124	histidyl-tRNA synthetase
Q31a_34760	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Q31a_34870	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Q31a_34880	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
Q31a_35040	COG0515	serine threonine protein kinase
Q31a_35040	COG2815	serine threonine protein kinase
Q31a_35090	COG0076	glutamate decarboxylase activity
Q31a_35110	COG0604	alcohol dehydrogenase
Q31a_35150	COG3119	arylsulfatase activity
Q31a_35160	COG3119	arylsulfatase activity
Q31a_35180	COG2197	response regulator
Q31a_35270	COG1172	Belongs to the binding-protein-dependent transport system permease family
Q31a_35280	COG1129	ABC transporter
Q31a_35300	COG1879	ABC-type sugar transport system periplasmic component
Q31a_35310	COG1869	D-ribose catabolic process
Q31a_35320	COG1063	alcohol dehydrogenase
Q31a_35380	COG1917	Cupin 2, conserved barrel domain protein
Q31a_35380	COG4977	sequence-specific DNA binding
Q31a_35410	COG1053	succinate dehydrogenase
Q31a_35620	COG0515	serine threonine protein kinase
Q31a_35620	COG2815	serine threonine protein kinase
Q31a_35710	COG2996	Protein conserved in bacteria
Q31a_35760	COG2815	serine threonine protein kinase
Q31a_35760	COG0515	serine threonine protein kinase
Q31a_35820	COG2084	Dehydrogenase
Q31a_35830	COG3395	kinase activity
Q31a_35840	COG0235	Class ii aldolase
Q31a_35850	COG3622	Belongs to the hyi family
Q31a_35870	COG0515	serine threonine protein kinase
Q31a_35870	COG2815	serine threonine protein kinase
Q31a_35960	COG0246	Mannitol dehydrogenase
Q31a_36200	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Q31a_36240	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Q31a_36290	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Q31a_36350	COG1111	helicase
Q31a_36350	COG1205	dead DEAH box helicase
Q31a_36430	COG2801	Transposase and inactivated derivatives
Q31a_36430	COG3415	Transposase
Q31a_36460	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Q31a_36620	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
Q31a_36640	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
Q31a_36650	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Q31a_36680	COG0564	pseudouridine synthase activity
Q31a_36700	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Q31a_36710	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Q31a_36740	COG2204	response regulator
Q31a_36770	COG4566	intracellular signal transduction
Q31a_36800	COG2855	membrane
Q31a_36840	COG1233	COG1233 Phytoene dehydrogenase and related
Q31a_36850	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Q31a_36890	COG3119	arylsulfatase activity
Q31a_36900	COG1024	Enoyl-CoA hydratase
Q31a_36910	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Q31a_36910	COG2755	lipolytic protein G-D-S-L family
Q31a_37020	COG0166	Belongs to the GPI family
Q31a_37060	COG1566	PFAM secretion protein HlyD family protein
Q31a_37090	COG0584	glycerophosphoryl diester phosphodiesterase
Q31a_37150	COG3119	arylsulfatase activity
Q31a_37160	COG2205	protein histidine kinase activity
Q31a_37170	COG0745	RESPONSE REGULATOR receiver
Q31a_37190	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Q31a_37210	COG1116	anion transmembrane transporter activity
Q31a_37220	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Q31a_37260	COG2814	Major facilitator Superfamily
Q31a_37280	COG0823	Involved in the tonB-independent uptake of proteins
Q31a_37320	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Q31a_37370	COG0515	serine threonine protein kinase
Q31a_37370	COG0457	Tetratricopeptide repeat
Q31a_37400	COG0574	Belongs to the PEP-utilizing enzyme family
Q31a_37400	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Q31a_37420	COG0793	Belongs to the peptidase S41A family
Q31a_37490	COG0525	valine-tRNA ligase activity
Q31a_37520	COG3547	Transposase (IS116 IS110 IS902 family)
Q31a_37540	COG0295	cytidine deaminase activity
Q31a_37560	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Q31a_37570	COG1053	succinate dehydrogenase
Q31a_37580	COG2009	succinate dehydrogenase
Q31a_37590	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Q31a_37650	COG1136	(ABC) transporter
Q31a_37670	COG4628	conserved protein (DUF2132)
Q31a_37680	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
Q31a_37700	COG3541	Predicted nucleotidyltransferase
Q31a_37810	COG1335	isochorismatase
Q31a_37840	COG0384	phenazine biosynthesis protein PhzF
Q31a_37870	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Q31a_37900	COG3119	arylsulfatase activity
Q31a_37930	COG1321	iron dependent repressor
Q31a_37960	COG1131	(ABC) transporter
Q31a_37990	COG2258	MOSC domain
Q31a_38050	COG3119	arylsulfatase activity
Q31a_38080	COG3119	arylsulfatase activity
Q31a_38190	COG0584	glycerophosphoryl diester phosphodiesterase
Q31a_38340	COG4149	molybdate abc transporter
Q31a_38350	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
Q31a_38370	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
Q31a_38390	COG0235	Class ii aldolase
Q31a_38400	COG3395	kinase activity
Q31a_38420	COG2271	Major facilitator Superfamily
Q31a_38450	COG2706	6-phosphogluconolactonase activity
Q31a_38510	COG1595	DNA-templated transcription, initiation
Q31a_38540	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Q31a_38550	COG1595	DNA-templated transcription, initiation
Q31a_38610	COG3119	arylsulfatase activity
Q31a_38640	COG3119	arylsulfatase activity
Q31a_38690	COG3119	arylsulfatase activity
Q31a_38710	COG1595	DNA-templated transcription, initiation
Q31a_38720	COG2815	serine threonine protein kinase
Q31a_38720	COG0515	serine threonine protein kinase
Q31a_38730	COG3119	arylsulfatase activity
Q31a_38750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q31a_38830	COG1716	ATPase activity
Q31a_38910	COG1191	sigma factor activity
Q31a_39100	COG0673	inositol 2-dehydrogenase activity
Q31a_39310	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Q31a_39330	COG0351	phosphomethylpyrimidine kinase
Q31a_39350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Q31a_39360	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Q31a_39450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q31a_39460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q31a_39500	COG0386	Belongs to the glutathione peroxidase family
Q31a_39550	COG0072	phenylalanine-tRNA ligase activity
Q31a_39560	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Q31a_39570	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Q31a_39580	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Q31a_39670	COG3119	arylsulfatase activity
Q31a_39690	COG0800	Aldolase
Q31a_39700	COG0673	inositol 2-dehydrogenase activity
Q31a_39770	COG1136	(ABC) transporter
Q31a_39780	COG4591	ABC-type transport system involved in lipoprotein release permease component
Q31a_39820	COG1869	D-ribose catabolic process
Q31a_39830	COG0667	Aldo Keto reductase
Q31a_39840	COG1640	4-alpha-glucanotransferase
Q31a_39850	COG0058	SHG alpha-glucan phosphorylase activity
Q31a_39890	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
Q31a_39980	COG3266	domain, Protein
Q31a_39980	COG4932	domain protein
Q31a_39980	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
Q31a_39990	COG0354	folic acid binding
Q31a_40040	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Q31a_40110	COG1216	Glycosyl transferase, family 2
Q31a_40140	COG0698	ribose 5-phosphate isomerase
Q31a_40150	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Q31a_40200	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
Q31a_40210	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Q31a_40240	COG3119	arylsulfatase activity
Q31a_40250	COG3119	arylsulfatase activity
Q31a_40270	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Q31a_40290	COG1073	alpha beta
Q31a_40400	COG3119	arylsulfatase activity
Q31a_40500	COG0515	serine threonine protein kinase
Q31a_40500	COG2815	serine threonine protein kinase
Q31a_40510	COG1595	DNA-templated transcription, initiation
Q31a_40550	COG3795	YCII-related domain
Q31a_40560	COG3795	YCII-related domain
Q31a_40600	COG4941	Belongs to the sigma-70 factor family
Q31a_40630	COG3361	conserved protein (COG2071)
Q31a_40640	COG1090	epimerase
Q31a_40650	COG1294	oxidase, subunit
Q31a_40660	COG1271	oxidase subunit
Q31a_40820	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Q31a_40840	COG1228	amidohydrolase
Q31a_40850	COG0546	phosphoglycolate phosphatase activity
Q31a_40890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Q31a_41100	COG2205	protein histidine kinase activity
Q31a_41150	COG2815	serine threonine protein kinase
Q31a_41150	COG0515	serine threonine protein kinase
Q31a_41220	COG2801	Transposase and inactivated derivatives
Q31a_41300	COG3119	arylsulfatase activity
Q31a_41390	COG0657	acetylesterase activity
Q31a_41400	COG3119	arylsulfatase activity
Q31a_41410	COG3119	arylsulfatase activity
Q31a_41440	COG3119	arylsulfatase activity
Q31a_41450	COG3119	arylsulfatase activity
Q31a_41470	COG2801	Transposase and inactivated derivatives
Q31a_41470	COG3415	Transposase
Q31a_41580	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Q31a_41580	COG1648	precorrin-2 dehydrogenase activity
Q31a_41610	COG2197	response regulator
Q31a_41730	COG0784	Response regulator, receiver
Q31a_41730	COG2205	protein histidine kinase activity
Q31a_42220	COG0464	growth
Q31a_42360	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Q31a_42960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Q31a_42980	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Q31a_43000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Q31a_43200	COG2189	Belongs to the N(4) N(6)-methyltransferase family
Q31a_43390	COG2217	Heavy metal translocating P-type atpase
Q31a_43410	COG2132	Multicopper oxidase
Q31a_43420	COG1937	Protein conserved in bacteria
Q31a_43520	COG1595	DNA-templated transcription, initiation
Q31a_43640	COG3118	belongs to the thioredoxin family
Q31a_43650	COG2217	Heavy metal translocating P-type atpase
Q31a_43840	COG0789	Transcriptional regulator
Q31a_43890	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Q31a_43950	COG2815	serine threonine protein kinase
Q31a_43950	COG0515	serine threonine protein kinase
Q31a_44030	COG4974	Belongs to the 'phage' integrase family
Q31a_44140	COG4804	nuclease activity
Q31a_44150	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
Q31a_44360	COG1475	DNA binding
Q31a_44640	COG1164	Oligoendopeptidase f
Q31a_44660	COG1073	alpha beta
Q31a_44670	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Q31a_44820	COG0440	acetolactate synthase activity
Q31a_44830	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Q31a_44840	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Q31a_44940	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
Q31a_44950	COG0489	protein tyrosine kinase activity
Q31a_44960	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
Q31a_44970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Q31a_45010	COG0110	maltose O-acetyltransferase activity
Q31a_45080	COG0297	glycogen (starch) synthase activity
Q31a_45080	COG0438	transferase activity, transferring glycosyl groups
Q31a_45090	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Q31a_45130	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Q31a_45150	COG1086	Polysaccharide biosynthesis protein
Q31a_45320	COG0714	Associated with various cellular activities
Q31a_45360	COG0288	reversible hydration of carbon dioxide
Q31a_45380	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
Q31a_45390	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Q31a_45420	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Q31a_45430	COG0187	DNA topoisomerase II activity
Q31a_45470	COG0714	Associated with various cellular activities
Q31a_45490	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Q31a_45510	COG1272	protein, Hemolysin III
Q31a_45530	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Q31a_45560	COG0494	nUDIX hydrolase
Q31a_45590	COG0175	sulfate reduction
Q31a_45610	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
Q31a_45620	COG0363	glucosamine-6-phosphate deaminase activity
Q31a_45630	COG0363	glucosamine-6-phosphate deaminase activity
Q31a_45650	COG0514	ATP-dependent DNA helicase (RecQ)
Q31a_45660	COG1013	pyruvate-flavodoxin oxidoreductase activity
Q31a_45670	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Q31a_45670	COG0674	pyruvate-flavodoxin oxidoreductase activity
Q31a_45680	COG0126	phosphoglycerate kinase activity
Q31a_45690	COG1609	Transcriptional regulator
Q31a_45710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Q31a_45720	COG1879	ABC-type sugar transport system periplasmic component
Q31a_45730	COG1129	ABC transporter
Q31a_45740	COG1172	Belongs to the binding-protein-dependent transport system permease family
Q31a_45770	COG0243	molybdopterin cofactor binding
Q31a_45800	COG0437	4 iron, 4 sulfur cluster binding
Q31a_45850	COG3119	arylsulfatase activity
Q31a_45860	COG1129	ABC transporter
Q31a_45870	COG1172	Belongs to the binding-protein-dependent transport system permease family
Q31a_45920	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
Q31a_46060	COG2195	Cleaves the N-terminal amino acid of tripeptides
Q31a_46100	COG0720	synthase
Q31a_46110	COG1694	Mazg nucleotide pyrophosphohydrolase
Q31a_46140	COG1090	epimerase
Q31a_46150	COG1686	Belongs to the peptidase S11 family
Q31a_46170	COG0284	orotidine-5'-phosphate decarboxylase activity
Q31a_46210	COG1194	a g-specific adenine glycosylase
Q31a_46250	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Q31a_46340	COG1228	amidohydrolase
Q31a_46380	COG2204	response regulator
Q31a_46390	COG2205	protein histidine kinase activity
Q31a_46430	COG3118	belongs to the thioredoxin family
Q31a_46460	COG0612	Peptidase, M16
Q31a_46480	COG0515	serine threonine protein kinase
Q31a_46500	COG0673	inositol 2-dehydrogenase activity
Q31a_46580	COG0719	Fe-S assembly protein
Q31a_46590	COG0719	Fe-S assembly protein
Q31a_46600	COG0396	ATPase activity
Q31a_46660	COG0686	Belongs to the AlaDH PNT family
Q31a_46670	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
Q31a_46690	COG1335	isochorismatase
Q31a_46710	COG3119	arylsulfatase activity
Q31a_46720	COG2133	pyrroloquinoline quinone binding
Q31a_46760	COG0540	Belongs to the ATCase OTCase family
Q31a_46770	COG0367	asparagine synthase
Q31a_46780	COG3119	arylsulfatase activity
Q31a_46790	COG4221	oxidoreductase activity
Q31a_46800	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Q31a_46830	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Q31a_46920	COG0590	tRNA wobble adenosine to inosine editing
Q31a_46960	COG1560	Kdo2-lipid A biosynthetic process
Q31a_46970	COG0363	glucosamine-6-phosphate deaminase activity
Q31a_47010	COG0811	peptide transport
Q31a_47070	COG1136	(ABC) transporter
Q31a_47080	COG1573	uracil-dna glycosylase
Q31a_47090	COG1160	GTP binding
Q31a_47100	COG0693	protein deglycase activity
Q31a_47440	COG2815	serine threonine protein kinase
Q31a_47440	COG0515	serine threonine protein kinase
Q31a_47490	COG0640	Transcriptional regulator
Q31a_47660	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Q31a_47670	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Q31a_47690	COG0167	dihydroorotate dehydrogenase activity
Q31a_47740	COG3209	COG3209 Rhs family protein
Q31a_47780	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Q31a_47780	COG4797	methyltransferase
Q31a_47920	COG0673	inositol 2-dehydrogenase activity
Q31a_47970	COG4191	Histidine kinase
Q31a_47970	COG0784	Response regulator, receiver
Q31a_48050	COG0702	epimerase
Q31a_48090	COG0366	Alpha amylase catalytic
Q31a_48100	COG0438	transferase activity, transferring glycosyl groups
Q31a_48110	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Q31a_48120	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Q31a_48130	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Q31a_48150	COG0356	it plays a direct role in the translocation of protons across the membrane
Q31a_48200	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Q31a_48220	COG0693	protein deglycase activity
Q31a_48260	COG2217	Heavy metal translocating P-type atpase
Q31a_48300	COG0058	SHG alpha-glucan phosphorylase activity
Q31a_48310	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Q31a_48320	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
Q31a_48330	COG0406	alpha-ribazole phosphatase activity
Q31a_48350	COG1129	ABC transporter
Q31a_48350	COG0842	Transport permease protein
Q31a_48370	COG2130	NADP-dependent
Q31a_48380	COG0167	dihydroorotate dehydrogenase activity
Q31a_48400	COG2204	response regulator
Q31a_48410	COG4191	Histidine kinase
Q31a_48420	COG2204	response regulator
Q31a_48430	COG4191	Histidine kinase
Q31a_48440	COG3852	Histidine kinase
Q31a_48500	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Q31a_48540	COG1858	cytochrome C peroxidase
Q31a_48590	COG0577	efflux transmembrane transporter activity
Q31a_48590	COG1136	(ABC) transporter
Q31a_48650	COG5002	protein histidine kinase activity
Q31a_48660	COG0745	RESPONSE REGULATOR receiver
Q31a_48690	COG0589	response to stress
Q31a_48700	COG1283	sodium-dependent phosphate transmembrane transporter activity
Q31a_48740	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Q31a_48770	COG1295	ribonuclease BN
Q31a_48780	COG0443	Heat shock 70 kDa protein
Q31a_48810	COG0515	serine threonine protein kinase
Q31a_48850	COG0563	adenylate kinase activity
Q31a_48930	COG2391	methyltransferase activity
Q31a_48940	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Q31a_48940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Q31a_48960	COG1028	Short-chain dehydrogenase reductase Sdr
Q31a_48990	COG3685	Protein conserved in bacteria
Q31a_49000	COG0288	reversible hydration of carbon dioxide
Q31a_49010	COG3781	membrane
Q31a_49030	COG1012	belongs to the aldehyde dehydrogenase family
Q31a_49040	COG0300	oxidoreductase activity
Q31a_49120	COG3119	arylsulfatase activity
Q31a_49230	COG3119	arylsulfatase activity
Q31a_49280	COG0456	acetyltransferase
Q31a_49290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Q31a_49320	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Q31a_49330	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Q31a_49370	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Q31a_49380	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
Q31a_49390	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Q31a_49420	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Q31a_49440	COG0069	glutamate synthase activity
Q31a_49470	COG1028	Short-chain dehydrogenase reductase Sdr
Q31a_49500	COG0450	alkyl hydroperoxide reductase
Q31a_49530	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Q31a_49570	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Q31a_49590	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Q31a_49610	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Q31a_49660	COG0148	phosphopyruvate hydratase activity
Q31a_49680	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Q31a_49690	COG2815	serine threonine protein kinase
Q31a_49690	COG0515	serine threonine protein kinase
Q31a_49700	COG1605	Chorismate mutase
Q31a_49700	COG0077	Prephenate dehydratase
Q31a_49710	COG0443	Heat shock 70 kDa protein
Q31a_49720	COG0542	response to heat
Q31a_49740	COG0275	rRNA processing
Q31a_49750	COG2001	Belongs to the MraZ family
Q31a_49760	COG1706	bacterial-type flagellum-dependent cell motility
Q31a_49770	COG1196	nuclear chromosome segregation
Q31a_49790	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Q31a_49800	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Q31a_49810	COG0314	molybdopterin synthase activity
Q31a_49830	COG0277	FAD linked oxidase domain protein
Q31a_49920	COG0617	tRNA 3'-terminal CCA addition
Q31a_49960	COG0142	geranyltranstransferase activity
Q31a_49970	COG0315	cyclic pyranopterin monophosphate synthase activity
Q31a_50020	COG1132	(ABC) transporter
Q31a_50040	COG4106	trans-aconitate 2-methyltransferase activity
Q31a_50090	COG4566	intracellular signal transduction
Q31a_50110	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Q31a_50120	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Q31a_50250	COG1450	Type ii and iii secretion system protein
Q31a_50270	COG3344	reverse transcriptase
Q31a_50300	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Q31a_50340	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Q31a_50440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q31a_50460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q31a_50510	COG2204	response regulator
Q31a_50520	COG3852	Histidine kinase
Q31a_50530	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Q31a_50540	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Q31a_50570	COG0659	secondary active sulfate transmembrane transporter activity
Q31a_50580	COG4191	Histidine kinase
Q31a_50590	COG2204	response regulator
Q31a_50630	COG0288	reversible hydration of carbon dioxide
Q31a_50670	COG0493	'glutamate synthase
Q31a_50670	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
Q31a_50720	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Q31a_50740	COG1104	cysteine desulfurase activity
Q31a_50750	COG4112	unkown
Q31a_50760	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Q31a_50770	COG0438	transferase activity, transferring glycosyl groups
Q31a_50780	COG0740	serine-type endopeptidase activity
Q31a_50790	COG0740	serine-type endopeptidase activity
Q31a_50800	COG0544	peptidyl-prolyl cis-trans isomerase activity
Q31a_50830	COG0305	Participates in initiation and elongation during chromosome replication
Q31a_50840	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Q31a_50850	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Q31a_50870	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Q31a_50880	COG0193	aminoacyl-tRNA hydrolase activity
Q31a_50890	COG0360	Binds together with S18 to 16S ribosomal RNA
Q31a_50900	COG0629	single-stranded DNA binding
Q31a_50910	COG0359	binds to the 23S rRNA
Q31a_50930	COG1476	TRANSCRIPTIONal
Q31a_50970	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Q31a_50990	COG4974	Belongs to the 'phage' integrase family
Q31a_51100	COG4626	Terminase
Q31a_51100	COG1802	Transcriptional regulator
Q31a_51310	COG4974	Belongs to the 'phage' integrase family
Q31a_51510	COG1073	alpha beta
Q31a_51670	COG1028	Short-chain dehydrogenase reductase Sdr
Q31a_51710	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
Q31a_51770	COG0481	GTPase activity
Q31a_51800	COG2354	Protein conserved in bacteria
Q31a_51920	COG0367	asparagine synthase
Q31a_51960	COG0438	transferase activity, transferring glycosyl groups
Q31a_51970	COG2192	nodulation
Q31a_51980	COG1696	Membrane protein involved in D-alanine export
Q31a_52000	COG0438	transferase activity, transferring glycosyl groups
Q31a_52070	COG1215	transferase activity, transferring glycosyl groups
Q31a_52210	COG2197	response regulator
Q31a_52230	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Q31a_52260	COG1136	(ABC) transporter
Q31a_52260	COG0577	efflux transmembrane transporter activity
Q31a_52420	COG1082	Xylose isomerase domain protein TIM barrel
Q31a_52440	COG3386	PFAM SMP-30 Gluconolaconase
Q31a_52450	COG3119	arylsulfatase activity
Q31a_52460	COG0316	Belongs to the HesB IscA family
Q31a_52480	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Q31a_52490	COG5002	protein histidine kinase activity
Q31a_52500	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
Q31a_52550	COG1606	tRNA processing
Q31a_52590	COG0356	it plays a direct role in the translocation of protons across the membrane
Q31a_52600	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Q31a_52610	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Q31a_52620	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Q31a_52630	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Q31a_52640	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Q31a_52650	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Q31a_52660	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Q31a_52680	COG0673	inositol 2-dehydrogenase activity
Q31a_52690	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Q31a_52720	COG1254	Belongs to the acylphosphatase family
Q31a_52740	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Q31a_52760	COG2379	hydroxypyruvate reductase
Q31a_52790	COG0515	serine threonine protein kinase
Q31a_52850	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Q31a_52870	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Q31a_52870	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Q31a_52900	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Q31a_53500	COG3547	Transposase (IS116 IS110 IS902 family)
Q31a_53630	COG1017	nitric oxide dioxygenase activity
Q31a_53630	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Q31a_53640	COG0571	ribonuclease III activity
Q31a_53650	COG0673	inositol 2-dehydrogenase activity
Q31a_53660	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Q31a_53670	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Q31a_53710	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Q31a_53730	COG1570	exodeoxyribonuclease VII activity
Q31a_53760	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Q31a_53770	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
Q31a_53780	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Q31a_53790	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Q31a_53800	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Q31a_53850	COG1063	alcohol dehydrogenase
Q31a_53860	COG0156	8-amino-7-oxononanoate synthase activity
Q31a_53880	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Q31a_53920	COG0363	glucosamine-6-phosphate deaminase activity
Q31a_53950	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Q31a_53960	COG1058	Belongs to the CinA family
Q31a_53960	COG1546	Belongs to the CinA family
Q31a_54010	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Q31a_54040	COG4771	TonB-dependent receptor
Q31a_54050	COG2239	Acts as a magnesium transporter
Q31a_54100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Q31a_54110	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Q31a_54210	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
Q31a_54250	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Q31a_54280	COG1214	PFAM Peptidase M22, glycoprotease
Q31a_54360	COG2204	response regulator
Q31a_54370	COG0045	succinate-CoA ligase (ADP-forming) activity
Q31a_54380	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
Q31a_54400	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Q31a_54440	COG0612	Peptidase, M16
Q31a_54450	COG0612	Peptidase, M16
Q31a_54470	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Q31a_54480	COG0484	heat shock protein binding
Q31a_54490	COG0459	protein refolding
Q31a_54500	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Q31a_54510	COG0459	protein refolding
Q31a_54540	COG0706	membrane insertase activity
Q31a_54540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q31a_54550	COG1760	l-serine dehydratase
Q31a_54670	COG0500	methyltransferase
Q31a_54710	COG0778	Nitroreductase
Q31a_54720	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
Q31a_54800	COG1181	Belongs to the D-alanine--D-alanine ligase family
Q31a_54820	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
Q31a_54860	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Q31a_54920	COG0445	tRNA wobble uridine modification
Q31a_54930	COG0745	RESPONSE REGULATOR receiver
Q31a_54940	COG3852	Histidine kinase
Q31a_54950	COG1757	Na H antiporter
Q31a_54980	COG1677	Flagellar hook-basal body complex protein FliE
Q31a_55010	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Q31a_55020	COG1419	protein localization to endoplasmic reticulum
Q31a_55050	COG1191	sigma factor activity
Q31a_55080	COG1157	protein secretion by the type III secretion system
Q31a_55120	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
Q31a_55160	COG1078	dGTPase activity
Q31a_55250	COG1136	(ABC) transporter
Q31a_55260	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Q31a_55270	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Q31a_55310	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Q31a_55380	COG0542	response to heat
Q31a_55430	COG0805	protein transport
Q31a_55440	COG1482	cell wall glycoprotein biosynthetic process
Q31a_55470	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Q31a_55470	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Q31a_55480	COG0335	large ribosomal subunit rRNA binding
Q31a_55490	COG0792	nuclease activity
Q31a_55520	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Q31a_55560	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Q31a_55600	COG0095	Lipoate-protein ligase
Q31a_55610	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Q31a_55620	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Q31a_55630	COG0509	glycine decarboxylation via glycine cleavage system
Q31a_55640	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Q31a_55670	COG0811	peptide transport
Q31a_55680	COG0848	biopolymer transport protein
Q31a_55710	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Q31a_55720	COG0628	permease
Q31a_55760	COG2815	serine threonine protein kinase
Q31a_55760	COG0515	serine threonine protein kinase
Q31a_55780	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Q31a_55790	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Q31a_55810	COG1722	exodeoxyribonuclease VII activity
Q31a_55840	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Q31a_55860	COG0563	adenylate kinase activity
Q31a_55870	COG1032	radical SAM domain protein
Q31a_55880	COG0604	alcohol dehydrogenase
Q31a_56000	COG2195	Cleaves the N-terminal amino acid of tripeptides
Q31a_56020	COG2226	methyltransferase
Q31a_56040	COG0515	serine threonine protein kinase
Q31a_56040	COG2815	serine threonine protein kinase
Q31a_56050	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Q31a_56080	COG0673	inositol 2-dehydrogenase activity
Q31a_56110	COG0583	DNA-binding transcription factor activity
Q31a_56120	COG0067	glutamate synthase
Q31a_56120	COG0070	glutamate synthase
Q31a_56120	COG0069	glutamate synthase activity
Q31a_56130	COG0493	'glutamate synthase
Q31a_56150	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Q31a_56160	COG4974	Belongs to the 'phage' integrase family
Q31a_56190	COG0811	peptide transport
Q31a_56230	COG0515	serine threonine protein kinase
Q31a_56230	COG2815	serine threonine protein kinase
Q31a_56240	COG0039	L-malate dehydrogenase activity
Q31a_56280	COG0215	cysteine-tRNA ligase activity
Q31a_56290	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Q31a_56300	COG0632	four-way junction helicase activity
Q31a_56320	COG0596	Alpha beta hydrolase
Q31a_56350	COG0594	ribonuclease P activity
Q31a_56360	COG1595	DNA-templated transcription, initiation
Q31a_56450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q31a_56470	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Q31a_56490	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Q31a_56540	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Q31a_56580	COG2135	peptidase activity
Q31a_56630	COG0564	pseudouridine synthase activity
Q31a_56690	COG2239	Acts as a magnesium transporter
Q31a_56700	COG1691	(AIR) carboxylase
Q31a_56710	COG0137	argininosuccinate synthase activity
Q31a_56730	COG1490	D-aminoacyl-tRNA deacylase activity
Q31a_56770	COG0825	malonyl-CoA metabolic process
Q31a_56780	COG0515	serine threonine protein kinase
Q31a_56790	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Q31a_56810	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Q31a_56970	COG0489	protein tyrosine kinase activity
Q31a_57020	COG1216	Glycosyl transferase, family 2
Q31a_57250	COG3119	arylsulfatase activity
Q31a_57340	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Q31a_57350	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Q31a_57360	COG2264	protein methyltransferase activity
Q31a_57380	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Q31a_57470	COG0848	biopolymer transport protein
Q31a_57480	COG0848	biopolymer transport protein
Q31a_57560	COG0457	Tetratricopeptide repeat
Q31a_57570	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
Q31a_57620	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
Q31a_57710	COG5002	protein histidine kinase activity
Q31a_57720	COG0704	Plays a role in the regulation of phosphate uptake
Q31a_57730	COG0745	RESPONSE REGULATOR receiver
Q31a_57740	COG0438	transferase activity, transferring glycosyl groups
Q31a_57770	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
Q31a_57780	COG0724	RNA recognition motif
Q31a_57790	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Q31a_57820	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Q31a_57830	COG0228	four-way junction DNA binding
Q31a_57840	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Q31a_57870	COG0004	ammonium transporteR
Q31a_57890	COG0552	protein localization to endoplasmic reticulum
Q31a_57910	COG0235	Class ii aldolase
Q31a_57950	COG4946	Tricorn protease homolog
Q31a_57950	COG0793	Belongs to the peptidase S41A family
Q31a_57960	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
Q31a_57970	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
Q31a_58030	COG0457	Tetratricopeptide repeat
Q31a_58030	COG0859	PFAM glycosyl transferase family 9
Q31a_58040	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Q31a_58090	COG2176	DNA-directed DNA polymerase activity
Q31a_58160	COG1063	alcohol dehydrogenase
Q31a_58170	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Q31a_58180	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Q31a_58200	COG1217	gtp-binding protein TYPA
Q31a_58240	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Q31a_58250	COG3706	GGDEF domain
Q31a_58270	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Q31a_58300	COG0628	permease
Q31a_58350	COG2205	protein histidine kinase activity
Q31a_58350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Q31a_58360	COG5487	UPF0391 membrane protein
Q31a_58410	COG3237	CsbD-like
Q31a_58460	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Q31a_58520	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Q31a_58530	COG2304	oxidoreductase activity
Q31a_58560	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
Q31a_58570	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Q31a_58600	COG2255	four-way junction helicase activity
Q31a_58670	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Q31a_58680	COG0196	riboflavin kinase activity
Q31a_58690	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Q31a_58720	COG1725	Transcriptional regulator
Q31a_58730	COG1131	(ABC) transporter
Q31a_58780	COG0423	glycine-tRNA ligase activity
Q31a_58790	COG2890	protein-(glutamine-N5) methyltransferase activity
Q31a_58800	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Q31a_58810	COG0254	rRNA binding
Q31a_58820	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Q31a_58840	COG0824	Thioesterase
Q31a_58890	COG1131	(ABC) transporter
Q31a_58920	COG0424	maF-like protein
Q31a_59020	COG0557	exoribonuclease II activity
Q31a_59040	COG0745	RESPONSE REGULATOR receiver
Q31a_59120	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Q31a_59130	COG1028	Short-chain dehydrogenase reductase Sdr
Q31a_59150	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Q31a_59160	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Q31a_59210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Q31a_59220	COG0676	glucose-6-phosphate 1-epimerase activity
Q31a_59260	COG0436	Aminotransferase
Q31a_59310	COG2271	Major facilitator Superfamily
Q31a_59320	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Q31a_59470	COG4536	flavin adenine dinucleotide binding
Q31a_59480	COG4536	flavin adenine dinucleotide binding
Q31a_59520	COG0071	Belongs to the small heat shock protein (HSP20) family
Q31a_59550	COG0352	thiamine-phosphate diphosphorylase activity
Q31a_59610	COG0517	IMP dehydrogenase activity
Q31a_59620	COG4974	Belongs to the 'phage' integrase family
Q31a_59730	COG1695	Transcriptional regulator
Q31a_59750	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Q31a_59770	COG1215	transferase activity, transferring glycosyl groups
Q31a_59790	COG1131	(ABC) transporter
Q31a_59810	COG1902	pentaerythritol trinitrate reductase activity
Q31a_59830	COG0202	RNA polymerase activity
Q31a_59850	COG0673	inositol 2-dehydrogenase activity
Q31a_59950	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Q31a_59970	COG1446	asparaginase
Q31a_60000	COG0746	molybdenum cofactor guanylyltransferase activity
Q31a_60020	COG5002	protein histidine kinase activity
Q31a_60030	COG0745	RESPONSE REGULATOR receiver
Q31a_60070	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Q31a_60130	COG1187	pseudouridine synthase activity
Q31a_60160	COG1815	bacterial-type flagellum-dependent cell motility
Q31a_60190	COG0336	Belongs to the RNA methyltransferase TrmD family
Q31a_60200	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Q31a_60230	COG0631	protein serine/threonine phosphatase activity
Q31a_60240	COG0174	glutamine synthetase
Q31a_60260	COG1477	protein flavinylation
Q31a_60270	COG2871	sodium ion transport
Q31a_60280	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Q31a_60290	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Q31a_60300	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Q31a_60310	COG1805	sodium ion transport
Q31a_60340	COG3119	arylsulfatase activity
Q31a_60390	COG1131	(ABC) transporter
Q31a_60420	COG1136	(ABC) transporter
Q31a_60420	COG0577	efflux transmembrane transporter activity
Q31a_60460	COG3263	regulation of cellular component size
Q31a_60510	COG1663	tetraacyldisaccharide 4'-kinase activity
Q31a_60520	COG2721	sulfolactate sulfo-lyase activity
Q31a_60550	COG3842	ATPase activity
Q31a_60670	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Q31a_60700	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Q31a_60710	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Q31a_60740	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Q31a_60820	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Q31a_60940	COG0483	inositol monophosphate 1-phosphatase activity
Q31a_60950	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Q31a_60970	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Q31a_61000	COG0631	protein serine/threonine phosphatase activity
Q31a_61030	COG4191	Histidine kinase
Q31a_61040	COG2204	response regulator
Q31a_61090	COG0714	Associated with various cellular activities
Q31a_61130	COG1132	(ABC) transporter
Q31a_61140	COG2003	Belongs to the UPF0758 family
Q31a_61150	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Q31a_61190	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Q31a_61200	COG1131	(ABC) transporter
Q31a_61230	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Q31a_61240	COG1684	flagellar biosynthetic protein fliR
Q31a_61260	COG1338	Plays a role in the flagellum-specific transport system
Q31a_61300	COG1360	Flagellar Motor Protein
Q31a_61310	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
Q31a_61320	COG1582	Flagellar protein (FlbD)
Q31a_61340	COG1162	GTPase activity
Q31a_61350	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Q31a_61360	COG0514	ATP-dependent DNA helicase (RecQ)
Q31a_61370	COG2045	Belongs to the ComB family
Q31a_61380	COG0159	tryptophan synthase activity
Q31a_61390	COG0133	tryptophan synthase activity
Q31a_61410	COG2192	nodulation
Q31a_61470	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Q31a_61610	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Q31a_61620	COG0195	Participates in both transcription termination and antitermination
Q31a_61630	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Q31a_61640	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Q31a_61660	COG0217	transcriptional regulatory protein
Q31a_61690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Q31a_61720	COG4221	oxidoreductase activity
Q31a_61730	COG3119	arylsulfatase activity
Q31a_61740	COG2115	Belongs to the xylose isomerase family
Q31a_61800	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
Q31a_61810	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Q31a_61820	COG0243	molybdopterin cofactor binding
Q31a_61830	COG0437	4 iron, 4 sulfur cluster binding
Q31a_61830	COG3064	Membrane
Q31a_61840	COG1116	anion transmembrane transporter activity
Q31a_61850	COG1116	anion transmembrane transporter activity
Q31a_61870	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Q31a_61870	COG1116	anion transmembrane transporter activity
Q31a_61940	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Q31a_61970	COG1063	alcohol dehydrogenase
Q31a_62100	COG3119	arylsulfatase activity
Q31a_62120	COG0515	serine threonine protein kinase
Q31a_62120	COG2815	serine threonine protein kinase
Q31a_62200	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
Q31a_62210	COG0438	transferase activity, transferring glycosyl groups
Q31a_62280	COG2096	Adenosyltransferase
Q31a_62300	COG0347	Belongs to the P(II) protein family
Q31a_62390	COG1940	carbohydrate kinase activity
Q31a_62420	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Q31a_62470	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Q31a_62570	COG0318	PFAM AMP-dependent synthetase and ligase
Q31a_62580	COG0189	ligase activity
Q31a_62590	COG3252	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT
Q31a_62600	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Q31a_62610	COG0540	Belongs to the ATCase OTCase family
Q31a_62620	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Q31a_62650	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
Q31a_62700	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Q31a_62870	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Q31a_62900	COG3119	arylsulfatase activity
Q31a_63030	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
Q31a_63080	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Q31a_63100	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Q31a_63140	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Q31a_63150	COG0154	amidase activity
Q31a_63160	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Q31a_63170	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Q31a_63250	COG0673	inositol 2-dehydrogenase activity
Q31a_63270	COG2322	membrane
Q31a_63330	COG0109	protoheme IX farnesyltransferase activity
Q31a_63350	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Q31a_63380	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Q31a_63420	COG1796	DNA polymerase
Q31a_63420	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Q31a_63430	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Q31a_63440	COG0457	Tetratricopeptide repeat
Q31a_63440	COG0515	serine threonine protein kinase
Q31a_63500	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Q31a_63560	COG0165	Argininosuccinate lyase
Q31a_63580	COG2204	response regulator
Q31a_63600	COG3132	Protein of unknown function, DUF480
Q31a_63670	COG1511	domain protein
Q31a_63670	COG3264	Mechanosensitive ion channel
Q31a_63720	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Q31a_63720	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Q31a_63760	COG1174	glycine betaine transport
Q31a_63870	COG0405	Gamma-glutamyltransferase
Q31a_63930	COG1129	ABC transporter
Q31a_63940	COG1172	Belongs to the binding-protein-dependent transport system permease family
Q31a_63970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Q31a_64000	COG0697	spore germination
Q31a_64020	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Q31a_64040	COG3590	peptidase
Q31a_64060	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Q31a_64090	COG0442	prolyl-tRNA aminoacylation
Q31a_64100	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
Q31a_64120	COG3481	metal-dependent phosphohydrolase, HD sub domain
Q31a_64140	COG1125	glycine betaine transport
Q31a_64140	COG0517	IMP dehydrogenase activity
Q31a_64150	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Q31a_64160	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Q31a_64170	COG0131	Imidazoleglycerol-phosphate dehydratase
Q31a_64190	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Q31a_64230	COG1216	Glycosyl transferase, family 2
Q31a_64240	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Q31a_64280	COG0151	Belongs to the GarS family
Q31a_64290	COG1331	Highly conserved protein containing a thioredoxin domain
Q31a_64330	COG1968	undecaprenyl-diphosphatase activity
Q31a_64340	COG1355	regulation of microtubule-based process
Q31a_64390	COG0482	sulfurtransferase activity
Q31a_64400	COG4864	UPF0365 protein
Q31a_64420	COG0506	proline dehydrogenase activity
Q31a_64420	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
Q31a_64420	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
Q31a_64430	COG0631	protein serine/threonine phosphatase activity
Q31a_64440	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
Q31a_64510	COG0673	inositol 2-dehydrogenase activity
Q31a_64530	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Q31a_64540	COG1082	Xylose isomerase domain protein TIM barrel
Q31a_64550	COG5285	phytanoyl-CoA dioxygenase
Q31a_64580	COG0243	molybdopterin cofactor binding
Q31a_64600	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
Q31a_64610	COG5002	protein histidine kinase activity
Q31a_64640	COG0504	CTP synthase activity
Q31a_64660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q31a_64700	COG3415	Transposase
Q31a_64700	COG2801	Transposase and inactivated derivatives
Q31a_64740	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Q31a_64750	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Q31a_64790	COG0714	Associated with various cellular activities
Q31a_64830	COG1216	Glycosyl transferase, family 2
Q31a_64850	COG3724	N-succinylarginine dihydrolase activity
Q31a_64880	COG1012	belongs to the aldehyde dehydrogenase family
Q31a_64890	COG1012	belongs to the aldehyde dehydrogenase family
Q31a_64900	COG1012	belongs to the aldehyde dehydrogenase family
Q31a_64970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q31a_64980	COG1295	ribonuclease BN
Q31a_65020	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Q31a_65030	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Q31a_65130	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Q31a_65150	COG0489	protein tyrosine kinase activity
Q31a_65180	COG1450	Type ii and iii secretion system protein
Q31a_65230	COG1459	type II secretion system
Q31a_65240	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Q31a_65260	COG5002	protein histidine kinase activity
Q31a_65300	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Q31a_65320	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Q31a_65340	COG1104	cysteine desulfurase activity