locus-tag	class	description
BVH56_00005	ENOG4105BZU	Histidine kinase
BVH56_00020	ENOG4105Q2H	domain protein
BVH56_00025	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
BVH56_00045	ENOG4105DVT	helicase
BVH56_00050	ENOG4105DVT	helicase
BVH56_00060	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
BVH56_00075	ENOG41081VB	Hydrolase
BVH56_00125	ENOG4108YYS	metal-dependent hydrolase (By similarity)
BVH56_00130	ENOG4105D01	(LipO)protein
BVH56_00135	ENOG4108UMI	ABC transporter, permease
BVH56_00140	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
BVH56_00160	ENOG4108TVJ	Nitroreductase
BVH56_00165	ENOG410606W	general stress protein
BVH56_00170	ENOG4105C94	Transporter
BVH56_00230	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
BVH56_00235	ENOG4105ETU	transcriptional activator (TenA
BVH56_00240	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
BVH56_00245	ENOG4105C26	Dehydrogenase
BVH56_00250	ENOG4105DFD	Na H antiporter
BVH56_00265	ENOG4105D7N	magnesium and cobalt transport protein CorA
BVH56_00270	ENOG4108IJ7	Glycine betaine
BVH56_00290	ENOG4105CHH	sulfate transporter
BVH56_00295	ENOG4107YZX	Universal stress protein
BVH56_00300	ENOG4105C94	Transporter
BVH56_00305	ENOG4105NAA	Cytochrome C oxidase, subunit II
BVH56_00310	ENOG4105BZ9	Cytochrome C oxidase, subunit I
BVH56_00315	ENOG4108KF3	Electron transport protein SCO1 SenC
BVH56_00330	ENOG4105DWT	malate dehydrogenase (quinone)
BVH56_00345	ENOG4108IUX	(ABC) transporter
BVH56_00350	ENOG4105RHA	ABC transporter, permease
BVH56_00390	ENOG4108U05	Transcriptional regulator
BVH56_00395	ENOG4107RA9	decarboxylase
BVH56_00405	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
BVH56_00410	ENOG4105HF9	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
BVH56_00415	ENOG4105XTG	Pfam:DUF156
BVH56_00420	ENOG41087NI	Sulfite exporter TauE/SafE
BVH56_00435	ENOG4105K78	MarR family Transcriptional regulator
BVH56_00440	ENOG4105C8J	)-transporter
BVH56_00450	ENOG4108X3M	OsmC Ohr family protein
BVH56_00455	ENOG4105E1F	short-chain dehydrogenase reductase
BVH56_00460	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
BVH56_00465	ENOG4108V06	Glutathione peroxidase
BVH56_00485	ENOG4105KPY	Small multidrug resistance protein
BVH56_00505	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
BVH56_00520	ENOG4108TV1	Catalyzes the incorporation of amino acid(s) into the interchain peptide bridge of peptidoglycan, using aminoacyl-tRNA as amino acid donor (By similarity)
BVH56_00530	ENOG4108IG5	Transcriptional regulator
BVH56_00550	ENOG4105F27	Major Facilitator
BVH56_00555	ENOG4105C7N	Xanthine uracil vitamin C permease
BVH56_00560	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
BVH56_00565	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
BVH56_00570	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
BVH56_00575	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
BVH56_00580	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BVH56_00585	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
BVH56_00590	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
BVH56_00595	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
BVH56_00600	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
BVH56_00605	ENOG41082SA	50s ribosomal protein l29
BVH56_00610	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
BVH56_00615	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
BVH56_00620	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
BVH56_00625	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BVH56_00630	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
BVH56_00635	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
BVH56_00640	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
BVH56_00645	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
BVH56_00650	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
BVH56_00655	ENOG4105VPB	50S ribosomal protein L30
BVH56_00660	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
BVH56_00665	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
BVH56_00670	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
BVH56_00685	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BVH56_00690	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
BVH56_00695	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BVH56_00700	ENOG4108ZT0	50S ribosomal protein l17
BVH56_00705	ENOG4108JJB	ABC transporter
BVH56_00710	ENOG4108JJB	ABC transporter
BVH56_00715	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
BVH56_00720	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
BVH56_00725	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
BVH56_00740	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
BVH56_00745	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
BVH56_00780	ENOG4108W8B	Beta-lactamase domain protein
BVH56_00805	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
BVH56_00815	ENOG4108W0I	acetyltransferase
BVH56_00845	ENOG4105IJJ	transcriptional regulator, crp fnr family
BVH56_00900	ENOG4107TXC	Transcriptional regulator
BVH56_00920	ENOG4105VZ8	Transcriptional regulator
BVH56_00935	ENOG4105CPU	Monooxygenase
BVH56_00940	ENOG4105CHR	reductase
BVH56_00945	ENOG4108RMH	femAB family
BVH56_00960	ENOG4105EXU	Membrane
BVH56_00990	ENOG4105EXC	Acyl-transferase
BVH56_01005	ENOG4105EWC	Purine nucleoside phosphorylase
BVH56_01010	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
BVH56_01015	ENOG4107QR9	Iron-sulfur cluster binding protein
BVH56_01020	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
BVH56_01025	ENOG4105DAA	L-lactate
BVH56_01035	ENOG4108F19	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
BVH56_01040	ENOG4105D7A	ATP-binding protein
BVH56_01045	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
BVH56_01070	ENOG4105YB8	TM2 domain containing protein
BVH56_01075	ENOG4108S4H	thioesterase Superfamily protein
BVH56_01090	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
BVH56_01100	ENOG4105C8P	)-transporter
BVH56_01105	ENOG4107JTW	chlorite dismutase
BVH56_01110	ENOG4108IJ2	phosphate acetyltransferase
BVH56_01115	ENOG4105JGI	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity)
BVH56_01135	ENOG4105DCI	Phosphohydrolase
BVH56_01150	ENOG4105C75	arginyL-tRNA synthetase
BVH56_01155	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
BVH56_01160	ENOG4105EHG	Permease protein
BVH56_01210	ENOG4105D06	uba thif-type nad fad binding protein
BVH56_01215	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
BVH56_01235	ENOG4105W8X	HesB YadR YfhF-family protein
BVH56_01240	ENOG4105H93	Acyltransferase family
BVH56_01260	ENOG4105KPY	Small multidrug resistance protein
BVH56_01265	ENOG4105KPY	Small multidrug resistance protein
BVH56_01270	ENOG4105FBA	Phospholipase Carboxylesterase
BVH56_01275	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
BVH56_01280	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
BVH56_01295	ENOG4108Z1Y	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling (By similarity)
BVH56_01310	ENOG4105HNY	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
BVH56_01315	ENOG4105FDK	ABC transporter
BVH56_01325	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
BVH56_01330	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
BVH56_01335	ENOG4105CBT	Fructose-1,6-bisphosphatase
BVH56_01340	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
BVH56_01345	ENOG41082DI	50s ribosomal protein l31
BVH56_01360	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
BVH56_01365	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
BVH56_01370	ENOG4107WAU	Protein tyrosine phosphatase
BVH56_01375	ENOG4108YZG	isomerase
BVH56_01385	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
BVH56_01395	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
BVH56_01405	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
BVH56_01410	ENOG4105WS6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
BVH56_01415	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
BVH56_01420	ENOG4107YZM	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
BVH56_01425	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
BVH56_01430	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
BVH56_01435	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
BVH56_01440	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
BVH56_01460	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
BVH56_01470	ENOG4108UUM	single-stranded DNA-binding protein
BVH56_01480	ENOG41069ER	domain protein
BVH56_01485	ENOG41069ER	domain protein
BVH56_01510	ENOG4107XQC	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity)
BVH56_01530	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
BVH56_01535	ENOG4105P4J	Allophanate hydrolase, subunit 1
BVH56_01540	ENOG4107R7A	Allophanate hydrolase subunit 2
BVH56_01545	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
BVH56_01550	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
BVH56_01555	ENOG4105E7W	lamb ycsf family protein
BVH56_01560	ENOG4105C5A	transporter
BVH56_01570	ENOG4105CPF	Cell wall formation (By similarity)
BVH56_01575	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
BVH56_01580	ENOG4105C1J	atp-dependent rna helicase
BVH56_01600	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
BVH56_01605	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
BVH56_01615	ENOG4107SGM	protein serine threonine phosphatase
BVH56_01620	ENOG4105WN5	stage II sporulation protein
BVH56_01625	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
BVH56_01685	ENOG410801F	ribosomal-protein-alanine acetyltransferase
BVH56_01690	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
BVH56_01705	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
BVH56_01720	ENOG4105C5H	ABC transporter
BVH56_01725	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
BVH56_01730	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
BVH56_01735	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
BVH56_01750	ENOG4105CSR	polyphosphate kinase 2
BVH56_01770	ENOG4105C94	Transporter
BVH56_01785	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
BVH56_01790	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
BVH56_01800	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
BVH56_01805	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
BVH56_01810	ENOG4105VEQ	Cold shock protein
BVH56_01840	ENOG4108NRW	Phospholipase, patatin family
BVH56_01850	ENOG4105CE4	GlcNAc 6-P deacetylase
BVH56_01870	ENOG4105DM4	PTS System
BVH56_01875	ENOG4105DE4	1-phosphofructokinase
BVH56_01880	ENOG4105E98	transcriptional regulator DeoR family
BVH56_01885	ENOG410749K	Uncharacterized protein conserved in bacteria (DUF2179)
BVH56_01890	ENOG4108ZHJ	Organic hydroperoxide resistance protein
BVH56_01900	ENOG4105KA0	thioesterase Superfamily protein
BVH56_01910	ENOG4105KPV	Transcriptional regulator
BVH56_01915	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
BVH56_01920	ENOG4108IJ8	ABC transporter
BVH56_01925	ENOG4105E90	ABC transporter
BVH56_01940	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
BVH56_01950	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
BVH56_01955	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
BVH56_01960	ENOG4108ISG	Major Facilitator
BVH56_01965	ENOG4105DAP	Nicotinate phosphoribosyltransferase
BVH56_01970	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
BVH56_02005	ENOG4105C83	adenylosuccinate lyase
BVH56_02010	ENOG4108VXD	carboxy-peptidase
BVH56_02020	ENOG4105C4R	Atp-dependent dna helicase
BVH56_02025	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
BVH56_02035	ENOG4105CK7	Sodium proline symporter
BVH56_02040	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
BVH56_02045	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
BVH56_02050	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
BVH56_02055	ENOG4105CFC	Transporter
BVH56_02065	ENOG4105CBD	Diacylglycerol kinase
BVH56_02070	ENOG4105CGH	5'-nucleotidase
BVH56_02115	ENOG4108V3A	UPF0421 protein
BVH56_02120	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
BVH56_02125	ENOG4108V2W	Carbonate dehydratase
BVH56_02150	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
BVH56_02175	ENOG41067AE	Membrane-bound metal-dependent hydrolase
BVH56_02180	ENOG4105CEN	a g-specific adenine glycosylase
BVH56_02185	ENOG4105EVI	UPF0374 protein
BVH56_02195	ENOG4105CBC	glutamate synthase
BVH56_02200	ENOG4108VX5	3-methyladenine DNA glycosylase
BVH56_02205	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
BVH56_02210	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BVH56_02215	ENOG4105G5W	regulator Fur family
BVH56_02220	ENOG4105TUA	UPF0295 protein
BVH56_02345	ENOG4105KWG	Pfam:DUF1696
BVH56_02355	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
BVH56_02360	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
BVH56_02365	ENOG4108DBC	nitroreductase
BVH56_02370	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
BVH56_02375	ENOG4105C9Q	fumarate hydratase class II
BVH56_02380	ENOG4107R33	ppx gppa phosphatase
BVH56_02385	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
BVH56_02390	ENOG4105EMS	pseudouridine synthase
BVH56_02400	ENOG4105KVY	Required for disulfide bond formation in some proteins (By similarity)
BVH56_02405	ENOG4105BZU	Histidine kinase
BVH56_02410	ENOG4105WH1	Two component transcriptional regulator luxr family
BVH56_02420	ENOG4108UH6	UPF0754 membrane protein
BVH56_02425	ENOG4105WZB	UPF0342 protein
BVH56_02430	ENOG4107VRP	DNA repair exonuclease
BVH56_02440	ENOG4105EQI	Metal Dependent Phosphohydrolase
BVH56_02445	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
BVH56_02460	ENOG4105K59	histidine triad (HIT) protein
BVH56_02490	ENOG4105C1Q	protoporphyrinogen oxidase
BVH56_02520	ENOG4107TS3	membrane protein, TerC
BVH56_02570	ENOG4108FQ0	the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis
BVH56_02575	ENOG41082BV	acetyltransferase
BVH56_02585	ENOG4108KGH	TRANSCRIPTIONal
BVH56_02620	ENOG4105EXC	Acyl-transferase
BVH56_02625	ENOG4105EY8	ABC transporter
BVH56_02645	ENOG4108I69	Glycosyl transferases group 1
BVH56_02650	ENOG4105HTX	biosynthesis protein
BVH56_02660	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
BVH56_02670	ENOG4107QQG	Dehydrogenase
BVH56_02675	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
BVH56_02705	ENOG4105D3Q	Sugar transferase
BVH56_02710	ENOG41080C8	DUF218 domain
BVH56_02715	ENOG4105EXC	Acyl-transferase
BVH56_02735	ENOG4105CIY	formyltetrahydrofolate deformylase
BVH56_02740	ENOG4108Z0Z	intracellular protease Pfpi family
BVH56_02760	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
BVH56_02765	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
BVH56_02790	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
BVH56_02800	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
BVH56_02805	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
BVH56_02810	ENOG4105DC1	bifunctional purine biosynthesis protein purh
BVH56_02815	ENOG4105C12	Phosphoribosylglycinamide synthetase
BVH56_02825	ENOG4105DR4	Methyltransferase
BVH56_02835	ENOG4105KRI	phosphocarrier protein (HPr
BVH56_02865	ENOG4107ZYR	domain protein
BVH56_02870	ENOG4105CN5	Metallo-Beta-Lactamase
BVH56_02875	ENOG4106148	UPF0356 protein
BVH56_02880	ENOG4108X4Q	Hydrolase
BVH56_02885	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
BVH56_02895	ENOG4105CPP	Dehydrogenase, E1 component
BVH56_02900	ENOG4105C7S	Dehydrogenase
BVH56_02905	ENOG4107QN2	dihydrolipoyl dehydrogenase
BVH56_02910	ENOG4105WBI	UPF0223 protein
BVH56_02925	ENOG4105F38	ABC transporter, permease
BVH56_02930	ENOG4105D38	putrescine abc transporter
BVH56_02935	ENOG4108HM4	ABC transporter
BVH56_02945	ENOG4108WQ8	UPF0637 protein
BVH56_02950	ENOG4105ECY	inositol monophosphatase
BVH56_02960	ENOG4105CI3	gtp-binding protein typa
BVH56_02965	ENOG4105QA2	
BVH56_02975	ENOG4105ZPI	UPF0358 protein
BVH56_02980	ENOG4105CNI	cell division protein FtsW
BVH56_02985	ENOG4107SGF	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
BVH56_02990	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
BVH56_03010	ENOG41064X9	cytochrome C oxidase subunit IV
BVH56_03030	ENOG4105F1V	Acetoin utilization protein
BVH56_03055	ENOG4105C26	Dehydrogenase
BVH56_03060	ENOG4108RMU	ferritin dps family protein
BVH56_03065	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
BVH56_03075	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
BVH56_03080	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
BVH56_03095	ENOG4105CHR	reductase
BVH56_03110	ENOG410787A	Pts system, glucitol sorbitol-specific
BVH56_03115	ENOG4105DZY	Pts system, glucitol sorbitol-specific
BVH56_03130	ENOG4105W5Q	DNA repair protein (RadC
BVH56_03135	ENOG4108FPN	Integrase
BVH56_03150	ENOG41064MX	Tetr family transcriptional regulator
BVH56_03155	ENOG4105F1N	DNA alkylation repair
BVH56_03170	ENOG4105BZ1	(ABC) transporter
BVH56_03175	ENOG4105BZ1	(ABC) transporter
BVH56_03190	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
BVH56_03205	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BVH56_03210	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
BVH56_03215	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
BVH56_03220	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
BVH56_03225	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
BVH56_03235	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
BVH56_03240	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
BVH56_03245	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
BVH56_03260	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
BVH56_03265	ENOG4105CUT	histidyl-tRNA synthetase
BVH56_03270	ENOG4105C9M	aspartyl-trna synthetase
BVH56_03285	ENOG4105CJ1	ABC, transporter
BVH56_03295	ENOG4105D1H	recombination factor protein RarA
BVH56_03305	ENOG4105DEN	Luciferase family
BVH56_03310	ENOG4105C3J	Cysteine desulfurase
BVH56_03315	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
BVH56_03325	ENOG4105C7H	Helicase, RecD TraA family
BVH56_03330	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
BVH56_03335	ENOG4105VBH	UPF0297 protein
BVH56_03340	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
BVH56_03345	ENOG4105VPH	UPF0473 protein
BVH56_03350	ENOG4105HHA	aminodeoxychorismate lyase
BVH56_03355	ENOG4108VQJ	O-methyltransferase
BVH56_03360	ENOG4105XYU	peptidase (U32 family)
BVH56_03365	ENOG4105CFP	Peptidase U32
BVH56_03370	ENOG4105DBI	uridine monophosphokinase
BVH56_03375	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
BVH56_03380	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
BVH56_03385	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
BVH56_03390	ENOG4105CQW	ribosome biogenesis GTPase YqeH
BVH56_03395	ENOG4105E2X	shikimate dehydrogenase
BVH56_03400	ENOG410812S	Rna-binding protein
BVH56_03405	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
BVH56_03410	ENOG4108WF2	Metal Dependent Phosphohydrolase
BVH56_03430	ENOG4105KQC	Competence protein
BVH56_03435	ENOG4108UK2	deaminase
BVH56_03455	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
BVH56_03460	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
BVH56_03465	ENOG4105CSA	Coproporphyrinogen iii oxidase
BVH56_03470	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
BVH56_03480	ENOG4105CFG	Acts as a chaperone (By similarity)
BVH56_03485	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
BVH56_03490	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
BVH56_03500	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
BVH56_03510	ENOG4105F7J	membrane-bound serine protease
BVH56_03515	ENOG4105DI5	UPF0365 protein
BVH56_03525	ENOG4105C9A	Phoh family
BVH56_03535	ENOG41080IJ	Diacylglycerol kinase
BVH56_03540	ENOG4105KG3	cytidine deaminase
BVH56_03545	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
BVH56_03550	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
BVH56_03565	ENOG4108M1Z	surface protein
BVH56_03575	ENOG4105DWT	malate dehydrogenase (quinone)
BVH56_03590	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
BVH56_03595	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
BVH56_03600	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
BVH56_03605	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BVH56_03625	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
BVH56_03630	ENOG4105C1J	atp-dependent rna helicase
BVH56_03635	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
BVH56_03640	ENOG4105FDK	ABC transporter
BVH56_03645	ENOG4105FAV	ABC, transporter
BVH56_03650	ENOG4105N80	Ferric uptake regulator, Fur family
BVH56_03655	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
BVH56_03665	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
BVH56_03670	ENOG4107RF6	penicillin-binding protein
BVH56_03675	ENOG4105EXS	phosphate abc transporter
BVH56_03680	ENOG4105C8U	phosphate abc transporter
BVH56_03685	ENOG4105E2Z	phosphate ABC transporter (Permease
BVH56_03690	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
BVH56_03695	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
BVH56_03700	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
BVH56_03730	ENOG4105C5X	domain protein
BVH56_03775	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
BVH56_03780	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BVH56_03785	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BVH56_03790	ENOG4105WZW	rhodanese family
BVH56_03795	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
BVH56_03800	ENOG4105CBJ	Metal-dependent enzyme
BVH56_03810	ENOG4105DC7	peptidase M24
BVH56_03815	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
BVH56_03825	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
BVH56_03835	ENOG4105M7K	Involved in the transcription termination process (By similarity)
BVH56_03840	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
BVH56_03845	ENOG41083BM	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
BVH56_03855	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
BVH56_03860	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
BVH56_03865	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
BVH56_03870	ENOG4106CCJ	Protein of unknown function (DUF2627)
BVH56_03880	ENOG4107RDP	Dehydrogenase
BVH56_03885	ENOG4105CKM	Branched-chain carboxylic acid kinase
BVH56_03890	ENOG4108Y6J	UPF0403 protein
BVH56_03895	ENOG4108QEG	Membrane
BVH56_03900	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
BVH56_03905	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
BVH56_03910	ENOG4108W3Q	Transcriptional regulator
BVH56_03915	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
BVH56_03920	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
BVH56_03930	ENOG4105CPC	Aldo Keto reductase
BVH56_03940	ENOG4105I3K	Ferric uptake regulator, Fur family
BVH56_03945	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BVH56_03955	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
BVH56_03960	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
BVH56_03965	ENOG4105FE9	pseudouridine synthase
BVH56_03970	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BVH56_03975	ENOG4107TWT	Cytochrome c biogenesis protein
BVH56_03980	ENOG4105CRE	cytochrome C
BVH56_03985	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BVH56_04010	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
BVH56_04015	ENOG4105HDK	L-asparaginase
BVH56_04020	ENOG4105CAT	Cytidine monophosphate kinase
BVH56_04030	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
BVH56_04035	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
BVH56_04040	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
BVH56_04055	ENOG4105K70	DNA-binding protein
BVH56_04070	ENOG4105EAH	synthase
BVH56_04075	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
BVH56_04080	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
BVH56_04090	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
BVH56_04115	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
BVH56_04120	ENOG4105PE6	Menaquinol-cytochrome c reductase, cytochrome b c subunit
BVH56_04135	ENOG4108Z5K	methylglyoxal synthase
BVH56_04140	ENOG4105CPK	Glycosyl transferase (Group 1
BVH56_04155	ENOG4105DVT	helicase
BVH56_04160	ENOG4105CHM	Aminotransferase
BVH56_04165	ENOG4105C5S	asparaginyl-tRNA synthetase
BVH56_04175	ENOG4105CSM	endonuclease III
BVH56_04205	ENOG4108UI2	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)
BVH56_04215	ENOG4108UKS	UPF0398 protein
BVH56_04220	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
BVH56_04230	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
BVH56_04235	ENOG4107RQ2	Cytochrome c oxidase, subunit I
BVH56_04240	ENOG4105NAA	Cytochrome C oxidase, subunit II
BVH56_04245	ENOG410890F	Dynamin family
BVH56_04265	ENOG4108XG4	DNA-binding transcriptional regulator
BVH56_04275	ENOG4107E54	Small Multidrug Resistance protein
BVH56_04310	ENOG4106QQ5	PBS lyase HEAT domain protein repeat-containing protein
BVH56_04315	ENOG4108Y6J	UPF0403 protein
BVH56_04325	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
BVH56_04335	ENOG4108FKN	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
BVH56_04340	ENOG4105E0X	reductase
BVH56_04345	ENOG4105C5Y	PTS System
BVH56_04350	ENOG4106E6V	UPF0346 protein
BVH56_04360	ENOG4105CN1	protease
BVH56_04365	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
BVH56_04370	ENOG410841Q	phosphoesterase PA-phosphatase related protein
BVH56_04380	ENOG4105GR3	Histidine kinase
BVH56_04385	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
BVH56_04405	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
BVH56_04410	ENOG4107T89	von Willebrand factor, type A
BVH56_04415	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
BVH56_04420	ENOG4105CDW	Resistance protein
BVH56_04430	ENOG410855V	Acylphosphatase
BVH56_04440	ENOG4105VEQ	Cold shock protein
BVH56_04445	ENOG4105C5H	ABC transporter
BVH56_04450	ENOG4105QNR	S1 RNA binding domain protein
BVH56_04455	ENOG4105DPN	Oligoendopeptidase f
BVH56_04465	ENOG4108RMH	femAB family
BVH56_04480	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
BVH56_04485	ENOG4105C59	p-type ATPase
BVH56_04500	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
BVH56_04510	ENOG4108RCF	TRANSCRIPTIONal
BVH56_04515	ENOG4105CI1	PTS System
BVH56_04520	ENOG4105CID	antiterminator
BVH56_04535	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BVH56_04540	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
BVH56_04550	ENOG4108I0Z	Aconitate hydratase
BVH56_04555	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
BVH56_04560	ENOG4108KF3	Electron transport protein SCO1 SenC
BVH56_04565	ENOG4105EYH	Exonuclease
BVH56_04570	ENOG4107RFY	SbcCD D subunit
BVH56_04600	ENOG4107QIV	Cytochrome c biogenesis protein
BVH56_04620	ENOG4105DZR	Type I site-specific deoxyribonuclease
BVH56_04630	ENOG4105CVR	type I restriction-modification system
BVH56_04635	ENOG4105VXM	UPF0154 protein
BVH56_04640	ENOG4105CV1	Transketolase (EC 2.2.1.1)
BVH56_04645	ENOG4105VPS	UPF0291 protein
BVH56_04675	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
BVH56_04680	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
BVH56_04685	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
BVH56_04690	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
BVH56_04700	ENOG4105C5F	glutamine synthetase
BVH56_04705	ENOG4105KV4	Transcriptional regulator
BVH56_04710	ENOG4105CXI	aluminum resistance protein
BVH56_04715	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
BVH56_04720	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
BVH56_04725	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
BVH56_04735	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
BVH56_04740	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
BVH56_04760	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
BVH56_04770	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
BVH56_04780	ENOG4108JJB	ABC transporter
BVH56_04785	ENOG4105NSK	ABC superfamily ATP binding cassette transporter membrane protein
BVH56_04795	ENOG4105DQU	oxidoreductase, subunit beta
BVH56_04800	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
BVH56_04805	ENOG4105D48	metallophosphoesterase
BVH56_04815	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
BVH56_04820	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
BVH56_04825	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
BVH56_04840	ENOG4108RKS	Short-chain dehydrogenase reductase Sdr
BVH56_04855	ENOG4105CNU	cell division protein FtsK
BVH56_04860	ENOG4105CN5	Metallo-Beta-Lactamase
BVH56_04865	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
BVH56_04875	ENOG4105DTN	riboflavin biosynthesis protein ribF
BVH56_04885	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
BVH56_04890	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
BVH56_04895	ENOG4105VHM	ribosomal protein
BVH56_04900	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
BVH56_04905	ENOG4105CHV	Transcription elongation factor NusA
BVH56_04910	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
BVH56_04915	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
BVH56_04920	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
BVH56_04935	ENOG4105KNE	Phosphatidate cytidylyltransferase
BVH56_04945	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
BVH56_04955	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
BVH56_04960	ENOG4105CE9	30S ribosomal protein S2
BVH56_04965	ENOG4105EUM	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor (By similarity)
BVH56_04970	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BVH56_04975	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
BVH56_04980	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
BVH56_04985	ENOG4105C79	DNA protecting protein DprA
BVH56_04990	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
BVH56_04995	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
BVH56_05005	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
BVH56_05010	ENOG4105CKK	Glycosyl transferase, family 2
BVH56_05020	ENOG4105EJV	Membrane
BVH56_05025	ENOG4105EJV	Membrane
BVH56_05030	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
BVH56_05035	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
BVH56_05040	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
BVH56_05060	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
BVH56_05065	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
BVH56_05070	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
BVH56_05075	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
BVH56_05080	ENOG4105CHR	reductase
BVH56_05100	ENOG4108Z6X	(sortase) family
BVH56_05105	ENOG4105CB5	ATP-dependent DNA helicase recG
BVH56_05115	ENOG4108ZAA	Alkaline-shock protein
BVH56_05120	ENOG4105VB9	50S ribosomal protein l28
BVH56_05135	ENOG4105DJV	ribulose-phosphate 3-epimerase
BVH56_05140	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
BVH56_05160	ENOG4108ZF3	Phosphatase
BVH56_05165	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
BVH56_05170	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
BVH56_05175	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
BVH56_05180	ENOG4105C25	Primosomal protein n'
BVH56_05185	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
BVH56_05195	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
BVH56_05200	ENOG4105F23	Fibronectin-binding protein
BVH56_05220	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
BVH56_05225	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
BVH56_05230	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
BVH56_05235	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
BVH56_05240	ENOG4105CD3	dihydroorotase
BVH56_05245	ENOG4105CXT	aspartate transcarbamylase
BVH56_05255	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
BVH56_05260	ENOG4105C34	Pseudouridine synthase
BVH56_05265	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
BVH56_05270	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
BVH56_05285	ENOG41067XK	integral membrane protein
BVH56_05290	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
BVH56_05295	ENOG4105DFA	alanine racemase domain protein
BVH56_05300	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
BVH56_05305	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
BVH56_05310	ENOG4108W8M	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity)
BVH56_05315	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
BVH56_05320	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
BVH56_05325	ENOG4105CJN	penicillin-binding protein
BVH56_05335	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
BVH56_05340	ENOG4108V6E	Cell division protein mraZ
BVH56_05345	ENOG41074B2	UPF0747 protein
BVH56_05350	ENOG41067VY	50S ribosomal protein L32
BVH56_05360	ENOG4105CDE	UPF0348 protein
BVH56_05365	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
BVH56_05370	ENOG4106H78	methyltransferase
BVH56_05395	ENOG4105D52	delta-aminolevulinic acid dehydratase
BVH56_05405	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
BVH56_05415	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
BVH56_05420	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
BVH56_05430	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
BVH56_05440	ENOG4105U6W	MutT NUDIX family protein
BVH56_05635	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
BVH56_05680	ENOG4105VTR	Integrase
BVH56_05695	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
BVH56_05700	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
BVH56_05705	ENOG4105E33	succinate dehydrogenase
BVH56_05715	ENOG4108NU2	Succinate dehydrogenase cytochrome b558 subunit
BVH56_05725	ENOG4105K63	Thioredoxin
BVH56_05730	ENOG4105C98	muts2 protein
BVH56_05735	ENOG4105DCG	PHP domain protein
BVH56_05745	ENOG410687F	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
BVH56_05750	ENOG4107FSS	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
BVH56_05760	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
BVH56_05765	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
BVH56_05770	ENOG4108RWN	rrna methyltransferase
BVH56_05775	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
BVH56_05780	ENOG4105CN9	Peptidase m42 family protein
BVH56_05785	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
BVH56_05790	ENOG4105VJV	50s ribosomal protein L35
BVH56_05795	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
BVH56_05800	ENOG4105C22	threonyL-tRNA synthetase
BVH56_05815	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
BVH56_05820	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
BVH56_05830	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
BVH56_05835	ENOG4105C2M	dna polymerase I
BVH56_05840	ENOG4105BZU	Histidine kinase
BVH56_05845	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
BVH56_05850	ENOG4108HMX	isocitrate dehydrogenase (NADP)
BVH56_05855	ENOG4105BZN	citrate synthase
BVH56_05865	ENOG4105CA9	Pyruvate kinase
BVH56_05870	ENOG4105CTQ	phosphohexokinase
BVH56_05880	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
BVH56_05890	ENOG4105C0B	DNA polymerase III (alpha subunit)
BVH56_05895	ENOG4105SFS	phosphoesterase RecJ domain protein
BVH56_05905	ENOG4105E8R	UPF0173 metal-dependent hydrolase
BVH56_05915	ENOG4105DCF	alanine dehydrogenase
BVH56_05920	ENOG4107YZX	Universal stress protein
BVH56_05925	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
BVH56_05935	ENOG4108KKH	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
BVH56_05940	ENOG4105EJ9	Membrane
BVH56_05945	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
BVH56_05950	ENOG4107QI6	Cysteine desulfurase
BVH56_05955	ENOG4105DGY	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization (By similarity)
BVH56_05960	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
BVH56_05965	ENOG4107YZX	Universal stress protein
BVH56_05970	ENOG4105DWD	nucleoside recognition domain protein
BVH56_05985	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
BVH56_05995	ENOG4105ETE	Transcriptional regulator (LacI family
BVH56_06000	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
BVH56_06010	ENOG4105MQN	general stress protein
BVH56_06015	ENOG4105DFU	Cell wall formation (By similarity)
BVH56_06020	ENOG4105CNU	cell division protein FtsK
BVH56_06045	ENOG4105C87	Aminotransferase class I and II
BVH56_06050	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
BVH56_06055	ENOG4108V15	phosphotransferase enzyme family
BVH56_06060	ENOG4107QSE	Dipeptidase
BVH56_06080	ENOG4105CBX	hi0933 family
BVH56_06090	ENOG410605W	Major Facilitator
BVH56_06095	ENOG4105N5T	Radical SAM Protein
BVH56_06115	ENOG4108Z0R	Transferase
BVH56_06135	ENOG4106A8V	Protein CrcB homolog
BVH56_06140	ENOG4105WMR	Protein CrcB homolog
BVH56_06175	ENOG4105XN3	extracellular solute-binding protein family 1
BVH56_06185	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
BVH56_06190	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
BVH56_06205	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
BVH56_06220	ENOG4108IPT	Naphthoate synthase
BVH56_06225	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
BVH56_06235	ENOG4105E4F	Isochorismate synthase
BVH56_06240	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
BVH56_06315	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
BVH56_06330	ENOG4108QBV	Monogalactosyldiacylglycerol synthase
BVH56_06335	ENOG4108PK2	permease that is required for glycolipid anchoring of LTA. May facilitate the transport of diglucosyl- diacylglycerol (Glc2-DAG) from the inner to the outer leaflet of the cytoplasmic membrane, delivering Glc2-DAG as a substrate for LTA synthesis, thereby generating glycolipid-anchored LTA. Appears to play an important role in virulence
BVH56_06340	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
BVH56_06345	ENOG4108VPC	n-acetylmuramoyl-l-alanine amidase
BVH56_06355	ENOG4105BZG	amino acid carrier protein
BVH56_06380	ENOG4105CJW	magnesium transporter
BVH56_06385	ENOG4105C34	Pseudouridine synthase
BVH56_06400	ENOG4106EFP	UPF0738 protein
BVH56_06405	ENOG4105MIX	Adenylate cyclase
BVH56_06410	ENOG4108Z18	K06886 hemoglobin
BVH56_06415	ENOG4105T58	Dithiol-disulfide isomerase
BVH56_06420	ENOG4105DPN	Oligoendopeptidase f
BVH56_06430	ENOG4108SQ7	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
BVH56_06435	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
BVH56_06440	ENOG4105C31	Tryptophanyl-tRNA synthetase
BVH56_06445	ENOG4108JQ7	(ABC) transporter
BVH56_06455	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
BVH56_06460	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
BVH56_06480	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
BVH56_06495	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
BVH56_06500	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
BVH56_06505	ENOG4107V6Q	Cyclic nucleotide-binding domain
BVH56_06515	ENOG4105VG1	fes assembly suf system protein
BVH56_06520	ENOG4108KP7	hydrolase
BVH56_06525	ENOG4105EPR	degv family
BVH56_06530	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
BVH56_06535	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
BVH56_06550	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
BVH56_06555	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BVH56_06575	ENOG4105D82	Glutamate dehydrogenase
BVH56_06580	ENOG4105C8Y	Acetylornithine aminotransferase
BVH56_06585	ENOG4105C26	Dehydrogenase
BVH56_06590	ENOG41060GV	RNA binding s1 domain protein
BVH56_06605	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
BVH56_06610	ENOG4105D65	subunit l
BVH56_06615	ENOG4105HC0	Na H antiporter
BVH56_06625	ENOG4108JPZ	Monovalent cation H antiporter subunit D
BVH56_06630	ENOG4105SC1	monovalent cation H antiporter subunit E
BVH56_06635	ENOG4105W4C	monovalent cation H antiporter subunit F
BVH56_06640	ENOG4105KJM	monovalent cation h antiporter subunit g
BVH56_06645	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
BVH56_06650	ENOG4107UVV	polysaccharide deacetylase
BVH56_06660	ENOG4107QJZ	Glycosyl transferase, family 2
BVH56_06665	ENOG410620I	Diguanylate cyclase
BVH56_06675	ENOG4105CEP	NADH dehydrogenase
BVH56_06680	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
BVH56_06685	ENOG4105ZKE	UPF0349 protein
BVH56_06700	ENOG41083MR	nifu domain-containing protein
BVH56_06705	ENOG4105VKD	bioY protein
BVH56_06710	ENOG4105C5I	Dehydrogenase
BVH56_06715	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
BVH56_06730	ENOG4105MMD	transcriptional regulator
BVH56_06735	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
BVH56_06750	ENOG4105EJQ	L-serine dehydratase
BVH56_06755	ENOG4107S6Z	Na H antiporter
BVH56_06760	ENOG4107R8B	5'-nucleotidase
BVH56_06770	ENOG4105I3N	Conserved Protein
BVH56_06775	ENOG4108IXI	(ABC) transporter
BVH56_06780	ENOG4105C4B	ABC transporter, permease
BVH56_06785	ENOG410681U	heavy metal transport detoxification protein
BVH56_06790	ENOG4105C59	p-type ATPase
BVH56_06795	ENOG4105VPX	protein, conserved in bacteria
BVH56_06805	ENOG4105DIW	FeS assembly protein SUFB
BVH56_06810	ENOG4108UNV	SUF system FeS assembly protein, NifU family
BVH56_06815	ENOG4105C9B	Cysteine desulfurase
BVH56_06820	ENOG4105JRK	feS assembly protein SufD
BVH56_06825	ENOG4105C3K	feS assembly ATPase SufC
BVH56_06840	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
BVH56_06845	ENOG41080E8	Transcriptional regulator, Spx MgsR family
BVH56_06850	ENOG4105SZ6	Thioredoxin
BVH56_06855	ENOG4107Y03	Nitroreductase
BVH56_06875	ENOG4108UXE	Protein tyrosine phosphatase
BVH56_06880	ENOG4105BZ1	(ABC) transporter
BVH56_06885	ENOG4105D01	(LipO)protein
BVH56_06890	ENOG4108UMI	ABC transporter, permease
BVH56_06895	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
BVH56_06900	ENOG4105M6F	mutator MutT protein
BVH56_06910	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
BVH56_06945	ENOG4105D7K	pfkb domain protein
BVH56_06965	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
BVH56_06970	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
BVH56_06980	ENOG4105XZU	Preprotein translocase, subunit SecG
BVH56_06985	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
BVH56_06990	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
BVH56_06995	ENOG4105CP7	Triose-phosphate isomerase
BVH56_07000	ENOG4105BZA	Phosphoglycerate kinase
BVH56_07040	ENOG4105CIE	May be required for sporulation (By similarity)
BVH56_07045	ENOG4105CHW	UPF0052 protein
BVH56_07050	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
BVH56_07055	ENOG4105C3M	thioredoxin reductase
BVH56_07065	ENOG4108S4C	acetyltransferase
BVH56_07075	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
BVH56_07080	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
BVH56_07100	ENOG4105K63	Thioredoxin
BVH56_07105	ENOG41069ER	domain protein
BVH56_07120	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
BVH56_07125	ENOG4105MS2	ribosomal subunit Interface protein
BVH56_07130	ENOG41081UC	Inherit from COG: Competence protein
BVH56_07140	ENOG4105EPR	degv family
BVH56_07145	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
BVH56_07150	ENOG4105ESV	Glycosyl transferase, family 4
BVH56_07155	ENOG4108KGH	TRANSCRIPTIONal
BVH56_07180	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
BVH56_07210	ENOG4105D4A	Cell wall formation (By similarity)
BVH56_07220	ENOG4108IPW	abc transporter atp-binding protein
BVH56_07225	ENOG4105CM4	permease protein
BVH56_07230	ENOG4105DHS	permease protein
BVH56_07245	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
BVH56_07250	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
BVH56_07255	ENOG4107ZAE	6-carboxy-5,6,7,8-tetrahydropterin synthase
BVH56_07260	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
BVH56_07270	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
BVH56_07275	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
BVH56_07290	ENOG4105DUX	Transporter
BVH56_07295	ENOG4108ZIE	5 nucleotidase deoxy cytosolic type C
BVH56_07300	ENOG4105C9U	ATP-dependent DNA helicase RecQ
BVH56_07305	ENOG4105E0M	Sulfatase
BVH56_07325	ENOG4105CRQ	synthase (Component I)
BVH56_07330	ENOG4105DDQ	anthranilate synthase
BVH56_07335	ENOG4105CZM	Major Facilitator
BVH56_07345	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
BVH56_07355	ENOG4105C37	(CBS) domain
BVH56_07360	ENOG4105CKI	cobalamin synthesis protein
BVH56_07365	ENOG4108JJA	ABC, transporter
BVH56_07370	ENOG4108JJ8	(ABC) transporter
BVH56_07380	ENOG4108URH	decarboxylase
BVH56_07405	ENOG4105CGH	5'-nucleotidase
BVH56_07410	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
BVH56_07415	ENOG4108R6K	riboflavin synthase, subunit alpha
BVH56_07420	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
BVH56_07425	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
BVH56_07455	ENOG4105DVE	abc transporter atp-binding protein
BVH56_07465	ENOG4105CDY	transcriptional regulatory protein
BVH56_07505	ENOG41067S9	phage shock protein C, PspC
BVH56_07510	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
BVH56_07515	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
BVH56_07595	ENOG4105D1F	ATP-binding protein
BVH56_07605	ENOG4105CGZ	zinc metallopeptidase
BVH56_07615	ENOG4105II7	pyrroline-5-carboxylate reductase
BVH56_07620	ENOG4108UT2	hemolysin iii
BVH56_07625	ENOG4108MYC	UTP-glucose-1-phosphate uridylyltransferase
BVH56_07645	ENOG4105E2K	Glycosyl transferase (Group 1
BVH56_07650	ENOG4105CMR	udp-glucose 4-epimerase
BVH56_07660	ENOG4105CKI	cobalamin synthesis protein
BVH56_07675	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BVH56_07680	ENOG4105BZU	Histidine kinase
BVH56_07685	ENOG4105C0H	protease
BVH56_07700	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
BVH56_07710	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
BVH56_07715	ENOG4105C94	Transporter
BVH56_07720	ENOG4107QPK	)-transporter
BVH56_07735	ENOG41090MY	MarR family Transcriptional regulator
BVH56_07740	ENOG4105C59	p-type ATPase
BVH56_07745	ENOG4105C2C	drug resistance transporter, Bcr CflA
BVH56_07755	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
BVH56_07760	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
BVH56_07765	ENOG4105C28	cystathionine
BVH56_07780	ENOG4105DFD	Na H antiporter
BVH56_07795	ENOG4105M08	Membrane
BVH56_07805	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
BVH56_07810	ENOG4105DWF	phosphomethylpyrimidine kinase
BVH56_07820	ENOG4107YEI	lmbE family
BVH56_07825	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
BVH56_07830	ENOG410667J	hydrolase
BVH56_07835	ENOG4108Z6B	deaminase
BVH56_07840	ENOG4105ZMH	deoxynucleoside kinase
BVH56_07845	ENOG4107XGZ	Hydrolase
BVH56_07850	ENOG4105CM2	brancheD-chain amino acid aminotransferase
BVH56_07865	ENOG4105E98	transcriptional regulator DeoR family
BVH56_07870	ENOG4105UQX	Mate efflux family protein
BVH56_07880	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
BVH56_07905	ENOG4105EXW	epimerase dehydratase
BVH56_07910	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
BVH56_07925	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
BVH56_07935	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
BVH56_07940	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
BVH56_07945	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BVH56_07950	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BVH56_07955	ENOG4107Y49	methyltransferase
BVH56_07960	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
BVH56_07965	ENOG4108VZM	50s ribosomal protein L10
BVH56_07970	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
BVH56_07975	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
BVH56_07980	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
BVH56_07985	ENOG410683Z	Preprotein translocase SecE subunit
BVH56_08000	ENOG4105M0M	Tetracycline resistance protein
BVH56_08005	ENOG4105C2N	RNA methyltransferase TrmH family group 3
BVH56_08010	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BVH56_08015	ENOG4105C8N	cysteinyl-tRNA synthetase
BVH56_08020	ENOG4105D7W	serine acetyltransferase
BVH56_08025	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
BVH56_08030	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
BVH56_08035	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
BVH56_08040	ENOG4105CTP	PilT protein domain protein
BVH56_08045	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
BVH56_08050	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
BVH56_08055	ENOG4105E0C	molybdate abc transporter
BVH56_08060	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
BVH56_08075	ENOG4108ZAF	Molybdopterin
BVH56_08085	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
BVH56_08090	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
BVH56_08095	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
BVH56_08120	ENOG4105BZU	Histidine kinase
BVH56_08140	ENOG4108IUE	nitrate reductase beta subunit
BVH56_08150	ENOG4105FJH	Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity)
BVH56_08165	ENOG41066A3	ATP guanido phosphotransferase
BVH56_08170	ENOG4108Z0C	Uvrb UvrC protein
BVH56_08175	ENOG4105KEX	transcriptional regulator, ctsr
BVH56_08180	ENOG4105D9N	nucleoside
BVH56_08225	ENOG4105EYF	MMPL domain protein
BVH56_08250	ENOG4105PGM	cation diffusion facilitator family transporter
BVH56_08255	ENOG4105KTU	Transcriptional regulator, arsr family
BVH56_08265	ENOG4107STQ	Multicopper oxidase
BVH56_08285	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BVH56_08290	ENOG4105BZU	Histidine kinase
BVH56_08325	ENOG41085FC	arsR family transcriptional regulator
BVH56_08345	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
BVH56_08350	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
BVH56_08355	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
BVH56_08405	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
BVH56_08410	ENOG4105EUJ	GTP cyclohydrolase i
BVH56_08425	ENOG4105C6T	cysteine synthase
BVH56_08430	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
BVH56_08435	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
BVH56_08440	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
BVH56_08445	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
BVH56_08450	ENOG41060GV	RNA binding s1 domain protein
BVH56_08460	ENOG41082I2	s4 domain protein
BVH56_08465	ENOG4108IY2	MazG family
BVH56_08475	ENOG4108JA2	transcriptioN-repair coupling factor
BVH56_08480	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
BVH56_08485	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
BVH56_08490	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
BVH56_08500	ENOG4105KME	endoribonuclease L-psp
BVH56_08505	ENOG4105DFT	pur operon repressor
BVH56_08510	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
BVH56_08515	ENOG4105W42	Veg protein
BVH56_08520	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
BVH56_08525	ENOG4105HVR	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity)
BVH56_08530	ENOG4105F8V	Hydrolase, tatD family
BVH56_08535	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
BVH56_08540	ENOG4105KRN	Transcriptional regulator, abrb family
BVH56_08545	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
BVH56_08550	ENOG4105VC4	domain protein
BVH56_08555	ENOG41060K3	Methyltransferase
BVH56_08565	ENOG4105MA4	psp1 domain protein
BVH56_08570	ENOG4107QRG	dna polymerase iii
BVH56_08575	ENOG4105X0R	protein from nitrogen regulatory protein P-II
BVH56_08580	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
BVH56_08585	ENOG4105CXN	decarboxylase
BVH56_08605	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
BVH56_08610	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
BVH56_08615	ENOG4105C6E	dna polymerase iii
BVH56_08625	ENOG4107414	GntR family transcriptional regulator
BVH56_08630	ENOG4105CG3	alpha amylase, catalytic region
BVH56_08635	ENOG4105C5Y	PTS System
BVH56_08640	ENOG4105G6Z	alkaline phosphatase
BVH56_08660	ENOG4108Z86	Glutamine amidotransferase
BVH56_08670	ENOG4105I2S	Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity)
BVH56_08675	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
BVH56_08700	ENOG4105CJZ	response regulator
BVH56_08790	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
BVH56_08795	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
BVH56_08800	ENOG4107KM7	Heat induced stress protein YflT
BVH56_08810	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
BVH56_08815	ENOG4108UUM	single-stranded DNA-binding protein
BVH56_08825	ENOG4105C3G	gtp-binding protein
BVH56_08830	ENOG4105D8X	mechanosensitive ion channel
BVH56_08835	ENOG4105FA0	parb-like partition protein
BVH56_08840	ENOG4107QJE	Chromosome Partitioning Protein
BVH56_08850	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
BVH56_08855	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
BVH56_08860	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
BVH56_08865	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
BVH56_08875	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
BVH56_08880	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
BVH56_08885	ENOG410848D	S4 domain protein YaaA
BVH56_08890	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
BVH56_08895	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BVH56_08910	ENOG4107FQX	Alpha-acetolactate decarboxylase
BVH56_08915	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
BVH56_08925	ENOG4105BZR	domain protein
BVH56_08930	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
BVH56_08935	ENOG4105CDU	Replicative dna helicase
BVH56_08940	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
BVH56_08945	ENOG4108JYZ	YitT family