locus-tag	class	description
DCC27_000020	COG0537	adenosine 5'-monophosphoramidase activity
DCC27_000035	COG0501	Belongs to the peptidase M48B family
DCC27_000045	COG1666	GTP binding
DCC27_000055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DCC27_000080	COG5646	InterPro IPR014922
DCC27_000130	COG2056	Na+-H+ antiporter family
DCC27_000135	COG1760	l-serine dehydratase
DCC27_000150	COG2030	dehydratase
DCC27_000155	COG2030	dehydratase
DCC27_000160	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DCC27_000165	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DCC27_000175	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DCC27_000180	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DCC27_000195	COG0456	acetyltransferase
DCC27_000195	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DCC27_000210	COG3485	protocatechuate 3,4-dioxygenase
DCC27_000230	COG0436	Aminotransferase
DCC27_000240	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DCC27_000245	COG0250	Participates in transcription elongation, termination and antitermination
DCC27_000250	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DCC27_000255	COG0081	regulation of translation
DCC27_000260	COG1113	amino acid transport
DCC27_000265	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DCC27_000270	COG0222	ribosome binding
DCC27_000275	COG0085	RNA polymerase activity
DCC27_000280	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DCC27_000310	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DCC27_000315	COG0049	tRNA binding
DCC27_000320	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DCC27_000325	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DCC27_000330	COG0051	transcription antitermination factor activity, RNA binding
DCC27_000335	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DCC27_000340	COG0088	Forms part of the polypeptide exit tunnel
DCC27_000345	COG0089	rRNA binding
DCC27_000350	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DCC27_000355	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DCC27_000360	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DCC27_000365	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DCC27_000370	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DCC27_000375	COG0255	Belongs to the universal ribosomal protein uL29 family
DCC27_000380	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DCC27_000385	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DCC27_000395	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DCC27_000400	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DCC27_000405	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DCC27_000415	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DCC27_000420	COG1841	ribosomal large subunit assembly
DCC27_000425	COG0200	Binds to the 23S rRNA
DCC27_000435	COG0563	adenylate kinase activity
DCC27_000445	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DCC27_000450	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DCC27_000455	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DCC27_000460	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DCC27_000465	COG0202	RNA polymerase activity
DCC27_000470	COG0203	ribosomal protein L17
DCC27_000475	COG0101	tRNA pseudouridine synthase activity
DCC27_000480	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DCC27_000485	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DCC27_000490	COG1126	abc transporter atp-binding protein
DCC27_000495	COG0765	amino acid transport
DCC27_000500	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DCC27_000510	COG1970	mechanosensitive ion channel activity
DCC27_000520	COG1072	(Pantothenic acid kinase))
DCC27_000530	COG0736	holo-[acyl-carrier-protein] synthase activity
DCC27_000535	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DCC27_000535	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DCC27_000540	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DCC27_000560	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DCC27_000565	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DCC27_000595	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DCC27_000600	COG0459	protein refolding
DCC27_000605	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DCC27_000605	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DCC27_000610	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DCC27_000615	COG0509	glycine decarboxylation via glycine cleavage system
DCC27_000620	COG1090	epimerase
DCC27_000630	COG0516	GMP reductase activity
DCC27_000645	COG0586	Pfam SNARE associated Golgi protein
DCC27_000650	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DCC27_000650	COG0519	Catalyzes the synthesis of GMP from XMP
DCC27_000695	COG3547	Transposase (IS116 IS110 IS902 family)
DCC27_000755	COG1722	exodeoxyribonuclease VII activity
DCC27_000760	COG1570	exodeoxyribonuclease VII activity
DCC27_000770	COG0471	metal ion transport
DCC27_000775	COG2197	response regulator
DCC27_000780	COG4585	Histidine kinase
DCC27_000790	COG1131	(ABC) transporter
DCC27_000795	COG1028	Short-chain dehydrogenase reductase Sdr
DCC27_000820	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DCC27_000825	COG0012	GTP binding
DCC27_000860	COG1396	sequence-specific DNA binding
DCC27_000905	COG1136	(ABC) transporter
DCC27_000915	COG0667	Aldo Keto reductase
DCC27_000930	COG1028	Short-chain dehydrogenase reductase Sdr
DCC27_000935	COG0596	Alpha beta hydrolase
DCC27_000950	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DCC27_000955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DCC27_000970	COG0395	ABC-type sugar transport system, permease component
DCC27_000975	COG1175	transmembrane transport
DCC27_000980	COG2807	transmembrane transport
DCC27_001020	COG1611	Belongs to the LOG family
DCC27_001045	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DCC27_001065	COG0006	proline dipeptidase activity
DCC27_001070	COG0613	PHP domain protein
DCC27_001090	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DCC27_001095	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DCC27_001100	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
DCC27_001110	COG0181	hydroxymethylbilane synthase activity
DCC27_001125	COG0113	porphobilinogen synthase activity
DCC27_001130	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DCC27_001180	COG3480	Lon protease (S16) C-terminal proteolytic domain
DCC27_001185	COG1615	UPF0182 protein
DCC27_001200	COG0803	Belongs to the bacterial solute-binding protein 9 family
DCC27_001210	COG1121	(ABC) transporter
DCC27_001215	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DCC27_001220	COG1842	Phage shock protein A
DCC27_001235	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DCC27_001245	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DCC27_001260	COG0482	sulfurtransferase activity
DCC27_001280	COG0714	Associated with various cellular activities
DCC27_001300	COG0745	RESPONSE REGULATOR receiver
DCC27_001305	COG5002	protein histidine kinase activity
DCC27_001305	COG5000	phosphorelay sensor kinase activity
DCC27_001310	COG5401	PFAM Sporulation and spore germination
DCC27_001315	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DCC27_001320	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DCC27_001325	COG0653	protein targeting
DCC27_001355	COG0489	protein tyrosine kinase activity
DCC27_001360	COG2902	Dehydrogenase
DCC27_001385	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DCC27_001390	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DCC27_001395	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DCC27_001400	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DCC27_001405	COG1674	ftsk spoiiie
DCC27_001445	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DCC27_001450	COG2884	Cell division ATP-binding protein ftsE
DCC27_001455	COG2177	Part of the ABC transporter FtsEX involved in
DCC27_001460	COG0739	heme binding
DCC27_001465	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DCC27_001475	COG1114	Component of the transport system for branched-chain amino acids
DCC27_001500	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DCC27_001505	COG0483	inositol monophosphate 1-phosphatase activity
DCC27_001515	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DCC27_001520	COG1595	DNA-templated transcription, initiation
DCC27_001540	COG0567	Dehydrogenase, E1 component
DCC27_001540	COG0508	dehydrogenase complex catalyzes the overall conversion of
DCC27_001550	COG1253	flavin adenine dinucleotide binding
DCC27_001555	COG1253	flavin adenine dinucleotide binding
DCC27_001565	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DCC27_001570	COG1121	(ABC) transporter
DCC27_001590	COG0537	adenosine 5'-monophosphoramidase activity
DCC27_001595	COG1643	Atp-dependent helicase
DCC27_001605	COG0018	arginyl-trna synthetase
DCC27_001610	COG0019	diaminopimelate decarboxylase activity
DCC27_001615	COG0460	homoserine dehydrogenase
DCC27_001620	COG0083	homoserine kinase activity
DCC27_001630	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DCC27_001635	COG2890	protein-(glutamine-N5) methyltransferase activity
DCC27_001655	COG0356	it plays a direct role in the translocation of protons across the membrane
DCC27_001660	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DCC27_001665	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DCC27_001670	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DCC27_001675	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DCC27_001680	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DCC27_001685	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DCC27_001690	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DCC27_001700	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DCC27_001705	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
DCC27_001740	COG1335	isochorismatase
DCC27_001750	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DCC27_001760	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DCC27_001765	COG1234	tRNA 3'-trailer cleavage
DCC27_001770	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DCC27_001775	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DCC27_001790	COG0420	3'-5' exonuclease activity
DCC27_001795	COG0419	ATPase involved in DNA repair
DCC27_001800	COG0579	oxidoreductase
DCC27_001835	COG0385	Bile acid
DCC27_001845	COG2873	o-acetylhomoserine
DCC27_001855	COG2391	methyltransferase activity
DCC27_001860	COG4172	Belongs to the ABC transporter superfamily
DCC27_001870	COG0601	transmembrane transport
DCC27_001890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DCC27_001905	COG0129	dihydroxy-acid dehydratase activity
DCC27_001915	COG0440	acetolactate synthase activity
DCC27_001920	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DCC27_001925	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DCC27_001935	COG0473	3-isopropylmalate dehydrogenase activity
DCC27_001940	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DCC27_001945	COG0179	Fumarylacetoacetate (FAA) hydrolase
DCC27_001950	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DCC27_001970	COG1414	Transcriptional regulator
DCC27_001975	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DCC27_001980	COG0066	3-isopropylmalate dehydratase activity
DCC27_001985	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DCC27_001995	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DCC27_002000	COG1181	Belongs to the D-alanine--D-alanine ligase family
DCC27_002010	COG1461	Dihydroxyacetone kinase
DCC27_002030	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DCC27_002040	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DCC27_002040	COG2755	lipolytic protein G-D-S-L family
DCC27_002055	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DCC27_002065	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DCC27_002070	COG1316	TRANSCRIPTIONal
DCC27_002075	COG0438	transferase activity, transferring glycosyl groups
DCC27_002080	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DCC27_002085	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DCC27_002100	COG1134	teichoic acid transport
DCC27_002115	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DCC27_002120	COG1196	nuclear chromosome segregation
DCC27_002125	COG0477	Major facilitator Superfamily
DCC27_002145	COG0228	four-way junction DNA binding
DCC27_002150	COG1837	Belongs to the UPF0109 family
DCC27_002155	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DCC27_002160	COG0336	Belongs to the RNA methyltransferase TrmD family
DCC27_002165	COG0335	large ribosomal subunit rRNA binding
DCC27_002170	COG0681	Belongs to the peptidase S26 family
DCC27_002175	COG0681	Belongs to the peptidase S26 family
DCC27_002180	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DCC27_002190	COG0792	nuclease activity
DCC27_002195	COG0606	chelatase, subunit chli
DCC27_002205	COG4974	Belongs to the 'phage' integrase family
DCC27_002220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DCC27_002225	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DCC27_002240	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DCC27_002265	COG2326	polyphosphate kinase activity
DCC27_002270	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DCC27_002280	COG1045	serine acetyltransferase
DCC27_002290	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DCC27_002295	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DCC27_002305	COG3022	response to hydroperoxide
DCC27_002325	COG0242	peptide deformylase activity
DCC27_002330	COG2329	Antibiotic biosynthesis monooxygenase
DCC27_002345	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DCC27_002390	COG0629	single-stranded DNA binding
DCC27_002425	COG0698	ribose 5-phosphate isomerase
DCC27_002435	COG0321	lipoyl(octanoyl) transferase activity
DCC27_002440	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DCC27_002455	COG0544	peptidyl-prolyl cis-trans isomerase activity
DCC27_002460	COG0740	serine-type endopeptidase activity
DCC27_002465	COG0740	serine-type endopeptidase activity
DCC27_002470	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DCC27_002475	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DCC27_002480	COG0525	valine-tRNA ligase activity
DCC27_002485	COG4221	oxidoreductase activity
DCC27_002490	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DCC27_002495	COG0285	dihydrofolate synthase activity
DCC27_002505	COG0105	UTP biosynthetic process
DCC27_002520	COG1530	ribonuclease E activity
DCC27_002525	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DCC27_002530	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DCC27_002535	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DCC27_002540	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DCC27_002555	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DCC27_002565	COG0799	negative regulation of ribosome biogenesis
DCC27_002570	COG0406	alpha-ribazole phosphatase activity
DCC27_002585	COG3547	Transposase (IS116 IS110 IS902 family)
DCC27_002605	COG1136	(ABC) transporter
DCC27_002605	COG0577	efflux transmembrane transporter activity
DCC27_002620	COG4585	Histidine kinase
DCC27_002625	COG2197	response regulator
DCC27_002635	COG0515	serine threonine protein kinase
DCC27_002650	COG1505	serine-type exopeptidase activity
DCC27_002660	COG0587	DNA-directed DNA polymerase activity
DCC27_002680	COG4221	oxidoreductase activity
DCC27_002690	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DCC27_002740	COG1309	transcriptional regulator
DCC27_002780	COG3173	Aminoglycoside phosphotransferase
DCC27_002805	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DCC27_002815	COG1960	acyl-CoA dehydrogenase activity
DCC27_002825	COG1309	transcriptional regulator
DCC27_002835	COG0798	PFAM Bile acid sodium symporter
DCC27_002875	COG2826	transposase and inactivated derivatives, IS30 family
DCC27_002920	COG0471	metal ion transport
DCC27_002925	COG0471	metal ion transport
DCC27_002930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DCC27_002940	COG1126	abc transporter atp-binding protein
DCC27_002945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DCC27_002960	COG4868	Belongs to the UPF0371 family
DCC27_002965	COG0561	phosphatase activity
DCC27_002980	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DCC27_002985	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DCC27_003005	COG2135	peptidase activity
DCC27_003015	COG0587	DNA-directed DNA polymerase activity
DCC27_003030	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DCC27_003090	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DCC27_003100	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DCC27_003110	COG0140	phosphoribosyl-ATP diphosphatase activity
DCC27_003115	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DCC27_003120	COG0107	imidazoleglycerol-phosphate synthase activity
DCC27_003130	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DCC27_003150	COG0134	indole-3-glycerol-phosphate synthase activity
DCC27_003155	COG0133	tryptophan synthase activity
DCC27_003160	COG0159	tryptophan synthase activity
DCC27_003165	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DCC27_003190	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DCC27_003190	COG2111	Na H antiporter
DCC27_003225	COG0539	negative regulation of cytoplasmic translation
DCC27_003230	COG0135	phosphoribosylanthranilate isomerase activity
DCC27_003240	COG1739	Uncharacterized protein family UPF0029
DCC27_003245	COG0237	dephospho-CoA kinase activity
DCC27_003250	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DCC27_003250	COG2755	lipolytic protein G-D-S-L family
DCC27_003255	COG0556	nucleotide-excision repair
DCC27_003260	COG0861	Integral membrane protein TerC family
DCC27_003275	COG4106	trans-aconitate 2-methyltransferase activity
DCC27_003295	COG0204	Acyl-transferase
DCC27_003295	COG0318	PFAM AMP-dependent synthetase and ligase
DCC27_003300	COG0322	excinuclease ABC activity
DCC27_003305	COG1660	Displays ATPase and GTPase activities
DCC27_003315	COG1481	regulation of sporulation
DCC27_003325	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DCC27_003330	COG0126	phosphoglycerate kinase activity
DCC27_003335	COG0149	triose-phosphate isomerase activity
DCC27_003340	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DCC27_003345	COG0363	glucosamine-6-phosphate deaminase activity
DCC27_003360	COG0166	Belongs to the GPI family
DCC27_003365	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DCC27_003375	COG0109	protoheme IX farnesyltransferase activity
DCC27_003410	COG0719	Fe-S assembly protein
DCC27_003415	COG0396	ATPase activity
DCC27_003420	COG2151	metal-sulfur cluster biosynthetic enzyme
DCC27_003435	COG0488	(ABC) transporter
DCC27_003465	COG1028	Short-chain dehydrogenase reductase Sdr
DCC27_003470	COG3830	Belongs to the UPF0237 family
DCC27_003470	COG0560	Phosphoserine phosphatase
DCC27_003475	COG1119	ATPase activity
DCC27_003490	COG0254	rRNA binding
DCC27_003525	COG1757	Na H antiporter
DCC27_003535	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DCC27_003540	COG0297	glycogen (starch) synthase activity
DCC27_003555	COG0183	Belongs to the thiolase family
DCC27_003560	COG1028	Short-chain dehydrogenase reductase Sdr
DCC27_003570	COG0438	transferase activity, transferring glycosyl groups
DCC27_003590	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DCC27_003595	COG1960	acyl-CoA dehydrogenase activity
DCC27_003610	COG1968	undecaprenyl-diphosphatase activity
DCC27_003615	COG0215	cysteine-tRNA ligase activity
DCC27_003625	COG0546	phosphoglycolate phosphatase activity
DCC27_003630	COG0517	IMP dehydrogenase activity
DCC27_003630	COG1994	Peptidase M50
DCC27_003640	COG1222	aaa ATPase
DCC27_003645	COG4122	O-methyltransferase activity
DCC27_003655	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DCC27_003670	COG2378	regulation of single-species biofilm formation
DCC27_003675	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DCC27_003680	COG0805	protein transport
DCC27_003685	COG4581	dead DEAH box helicase
DCC27_003695	COG1216	Glycosyl transferase, family 2
DCC27_003720	COG0710	3-dehydroquinate dehydratase activity
DCC27_003740	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DCC27_003750	COG1845	cytochrome c oxidase, subunit III
DCC27_003755	COG2010	Cytochrome c
DCC27_003760	COG0723	plastoquinol--plastocyanin reductase activity
DCC27_003765	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DCC27_003770	COG2130	NADP-dependent
DCC27_003790	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DCC27_003810	COG2130	NADP-dependent
DCC27_003820	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DCC27_003825	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DCC27_003850	COG0167	dihydroorotate dehydrogenase activity
DCC27_003860	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DCC27_003865	COG1381	Involved in DNA repair and RecF pathway recombination
DCC27_003870	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DCC27_003875	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DCC27_003885	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DCC27_003900	COG0484	heat shock protein binding
DCC27_003905	COG1420	regulation of RNA biosynthetic process
DCC27_003925	COG0481	GTPase activity
DCC27_003930	COG0268	Binds directly to 16S ribosomal RNA
DCC27_003935	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
DCC27_003940	COG1473	amidohydrolase
DCC27_003990	COG1674	ftsk spoiiie
DCC27_004015	COG2333	competence protein COMEC
DCC27_004015	COG0658	competence protein
DCC27_004020	COG1555	photosystem II stabilization
DCC27_004020	COG1596	polysaccharide export
DCC27_004025	COG1307	EDD domain protein, DegV family
DCC27_004030	COG0495	leucyl-tRNA aminoacylation
DCC27_004040	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DCC27_004050	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DCC27_004055	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DCC27_004075	COG1758	RNA polymerase activity
DCC27_004080	COG0194	GDP metabolic process
DCC27_004090	COG0284	orotidine-5'-phosphate decarboxylase activity
DCC27_004095	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DCC27_004110	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DCC27_004115	COG0540	Belongs to the ATCase OTCase family
DCC27_004120	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DCC27_004125	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DCC27_004130	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DCC27_004135	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DCC27_004145	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DCC27_004150	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DCC27_004155	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DCC27_004160	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DCC27_004165	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DCC27_004175	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DCC27_004185	COG1490	D-aminoacyl-tRNA deacylase activity
DCC27_004195	COG0488	(ABC) transporter
DCC27_004205	COG2814	Major facilitator Superfamily
DCC27_004245	COG1131	(ABC) transporter
DCC27_004260	COG1309	transcriptional regulator
DCC27_004280	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DCC27_004285	COG0124	histidyl-tRNA synthetase
DCC27_004290	COG1196	nuclear chromosome segregation
DCC27_004300	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DCC27_004305	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DCC27_004310	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DCC27_004320	COG2255	four-way junction helicase activity
DCC27_004325	COG0632	four-way junction helicase activity
DCC27_004330	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DCC27_004335	COG0217	transcriptional regulatory protein
DCC27_004345	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DCC27_004355	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
DCC27_004375	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DCC27_004380	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DCC27_004390	COG0756	dUTP diphosphatase activity
DCC27_004425	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DCC27_004430	COG4988	ABC transporter
DCC27_004435	COG1294	oxidase, subunit
DCC27_004440	COG1271	oxidase subunit
DCC27_004465	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DCC27_004470	COG0187	DNA topoisomerase II activity
DCC27_004480	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DCC27_004495	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DCC27_004500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DCC27_004505	COG0508	dehydrogenase complex catalyzes the overall conversion of
DCC27_004530	COG0174	glutamine synthetase
DCC27_004535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DCC27_004540	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DCC27_004545	COG0174	glutamine synthetase
DCC27_004550	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DCC27_004555	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DCC27_004570	COG1940	carbohydrate kinase activity
DCC27_004575	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DCC27_004580	COG0587	DNA-directed DNA polymerase activity
DCC27_004590	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DCC27_004595	COG3599	regulation of cell shape
DCC27_004605	COG1799	cell septum assembly
DCC27_004615	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DCC27_004620	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DCC27_004625	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DCC27_004630	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DCC27_004640	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DCC27_004645	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DCC27_004655	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DCC27_004660	COG0768	penicillin binding
DCC27_004670	COG0275	rRNA processing
DCC27_004675	COG2001	Belongs to the MraZ family
DCC27_004690	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DCC27_004705	COG1388	LysM domain
DCC27_004705	COG3942	CHAP domain
DCC27_004710	COG2815	serine threonine protein kinase
DCC27_004710	COG0515	serine threonine protein kinase
DCC27_004715	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
DCC27_004730	COG1022	Amp-dependent synthetase and ligase
DCC27_004740	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DCC27_004760	COG1716	ATPase activity
DCC27_004770	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DCC27_004775	COG1160	GTP binding
DCC27_004780	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DCC27_004795	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DCC27_004820	COG0497	DNA recombination
DCC27_004825	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DCC27_004835	COG0647	UMP catabolic process
DCC27_004845	COG0508	dehydrogenase complex catalyzes the overall conversion of
DCC27_004850	COG0022	dehydrogenase e1 component
DCC27_004855	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DCC27_004875	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DCC27_004885	COG0165	Argininosuccinate lyase
DCC27_004895	COG1438	arginine binding
DCC27_004900	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DCC27_004905	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DCC27_004910	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DCC27_004915	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DCC27_004920	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DCC27_004930	COG0072	phenylalanine-tRNA ligase activity
DCC27_004930	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DCC27_004935	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DCC27_004955	COG0183	Belongs to the thiolase family
DCC27_004960	COG0318	PFAM AMP-dependent synthetase and ligase
DCC27_004965	COG1309	transcriptional regulator
DCC27_004970	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DCC27_004980	COG1960	acyl-CoA dehydrogenase activity
DCC27_005000	COG0583	DNA-binding transcription factor activity
DCC27_005010	COG0351	phosphomethylpyrimidine kinase
DCC27_005010	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DCC27_005010	COG0352	thiamine-phosphate diphosphorylase activity
DCC27_005015	COG0351	phosphomethylpyrimidine kinase
DCC27_005020	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DCC27_005040	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DCC27_005050	COG0010	Belongs to the arginase family
DCC27_005055	COG1228	amidohydrolase
DCC27_005060	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DCC27_005100	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DCC27_005105	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DCC27_005110	COG0131	Imidazoleglycerol-phosphate dehydratase
DCC27_005115	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DCC27_005120	COG1388	LysM domain
DCC27_005125	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DCC27_005130	COG0471	metal ion transport
DCC27_005145	COG2813	Specifically methylates the guanine in position
DCC27_005155	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DCC27_005160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DCC27_005170	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DCC27_005180	COG1396	sequence-specific DNA binding
DCC27_005185	COG1546	Belongs to the CinA family
DCC27_005185	COG1058	Belongs to the CinA family
DCC27_005195	COG1674	ftsk spoiiie
DCC27_005200	COG0662	Cupin 2, conserved barrel domain protein
DCC27_005205	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DCC27_005210	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DCC27_005225	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DCC27_005230	COG1115	amino acid carrier protein
DCC27_005235	COG2826	transposase and inactivated derivatives, IS30 family
DCC27_005270	COG4133	protoheme IX ABC transporter activity
DCC27_005310	COG2826	transposase and inactivated derivatives, IS30 family
DCC27_005320	COG0612	Peptidase, M16
DCC27_005330	COG1185	polyribonucleotide nucleotidyltransferase activity
DCC27_005335	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DCC27_005370	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DCC27_005375	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DCC27_005380	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DCC27_005395	COG0779	Required for maturation of 30S ribosomal subunits
DCC27_005405	COG0442	prolyl-tRNA aminoacylation
DCC27_005425	COG0750	zinc metalloprotease
DCC27_005445	COG0233	cytoplasmic translational termination
DCC27_005450	COG0528	UMP kinase activity
DCC27_005455	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DCC27_005460	COG0052	Belongs to the universal ribosomal protein uS2 family
DCC27_005465	COG0745	RESPONSE REGULATOR receiver
DCC27_005470	COG2205	protein histidine kinase activity
DCC27_005500	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DCC27_005520	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DCC27_005535	COG0352	thiamine-phosphate diphosphorylase activity
DCC27_005540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DCC27_005545	COG2801	Transposase and inactivated derivatives
DCC27_005545	COG3415	Transposase
DCC27_005560	COG2022	thiamine diphosphate biosynthetic process
DCC27_005570	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DCC27_005590	COG0358	DNA primase activity
DCC27_005680	COG2226	methyltransferase
DCC27_005685	COG0798	PFAM Bile acid sodium symporter
DCC27_005695	COG2072	flavoprotein involved in K transport
DCC27_005730	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DCC27_005735	COG0318	PFAM AMP-dependent synthetase and ligase
DCC27_005740	COG1960	acyl-CoA dehydrogenase activity
DCC27_005745	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DCC27_005760	COG1024	Enoyl-CoA hydratase
DCC27_005780	COG0423	glycine-tRNA ligase activity
DCC27_005790	COG0737	Belongs to the 5'-nucleotidase family
DCC27_005800	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DCC27_005805	COG2873	o-acetylhomoserine
DCC27_005810	COG1643	Atp-dependent helicase
DCC27_005840	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DCC27_005845	COG0154	amidase activity
DCC27_005850	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DCC27_005865	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DCC27_005870	COG0631	protein serine/threonine phosphatase activity
DCC27_005890	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DCC27_005900	COG0424	maF-like protein
DCC27_005905	COG4770	biotin carboxylase activity
DCC27_005910	COG0477	Major facilitator Superfamily
DCC27_005925	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DCC27_005930	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DCC27_005960	COG1309	transcriptional regulator
DCC27_005970	COG0193	aminoacyl-tRNA hydrolase activity
DCC27_005975	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DCC27_005985	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DCC27_005995	COG3842	ATPase activity
DCC27_006000	COG1178	ABC-type Fe3 transport system permease component
DCC27_006025	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DCC27_006030	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DCC27_006040	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DCC27_006040	COG1321	iron dependent repressor
DCC27_006055	COG0519	Catalyzes the synthesis of GMP from XMP
DCC27_006065	COG0583	DNA-binding transcription factor activity
DCC27_006070	COG0488	(ABC) transporter
DCC27_006080	COG2962	Rard protein
DCC27_006085	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DCC27_006115	COG2197	response regulator
DCC27_006120	COG4585	Histidine kinase
DCC27_006125	COG1131	(ABC) transporter
DCC27_006145	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DCC27_006160	COG2226	methyltransferase
DCC27_006190	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DCC27_006195	COG1819	glycosyl
DCC27_006210	COG0583	DNA-binding transcription factor activity
DCC27_006215	COG0488	(ABC) transporter
DCC27_006220	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DCC27_006225	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DCC27_006230	COG3583	domain protein
DCC27_006235	COG0084	hydrolase, TatD family'
DCC27_006245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DCC27_006260	COG2188	Transcriptional regulator
DCC27_006265	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DCC27_006285	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DCC27_006310	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DCC27_006355	COG1316	TRANSCRIPTIONal
DCC27_006360	COG1482	cell wall glycoprotein biosynthetic process
DCC27_006375	COG0288	reversible hydration of carbon dioxide
DCC27_006380	COG0114	fumarate hydratase activity
DCC27_006395	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DCC27_006405	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DCC27_006410	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DCC27_006420	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DCC27_006430	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DCC27_006440	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DCC27_006500	COG0395	ABC-type sugar transport system, permease component
DCC27_006505	COG1175	transmembrane transport
DCC27_006515	COG3547	Transposase (IS116 IS110 IS902 family)
DCC27_006520	COG0148	phosphopyruvate hydratase activity
DCC27_006530	COG3956	TIGRFAM MazG family protein
DCC27_006535	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DCC27_006555	COG1473	amidohydrolase
DCC27_006555	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DCC27_006565	COG2009	succinate dehydrogenase
DCC27_006580	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DCC27_006605	COG3842	ATPase activity
DCC27_006700	COG0789	Transcriptional regulator
DCC27_006815	COG1674	ftsk spoiiie
DCC27_006820	COG0180	Tryptophanyl-tRNA synthetase
DCC27_006845	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DCC27_006850	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DCC27_006930	COG2066	Belongs to the glutaminase family
DCC27_006930	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
DCC27_006935	COG2838	Isocitrate dehydrogenase
DCC27_006940	COG2239	Acts as a magnesium transporter
DCC27_006945	COG0138	bifunctional purine biosynthesis protein purh
DCC27_006965	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DCC27_006995	COG2149	membrane
DCC27_007005	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DCC27_007020	COG0045	succinate-CoA ligase (ADP-forming) activity
DCC27_007055	COG0791	NLP P60 protein
DCC27_007055	COG1388	LysM domain
DCC27_007055	COG3103	Sh3 type 3 domain protein
DCC27_007065	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DCC27_007095	COG0745	RESPONSE REGULATOR receiver
DCC27_007100	COG2205	protein histidine kinase activity
DCC27_007115	COG0459	protein refolding
DCC27_007130	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DCC27_007225	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DCC27_007230	COG0366	Alpha amylase catalytic
DCC27_007235	COG1116	anion transmembrane transporter activity
DCC27_007235	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DCC27_007240	COG4211	Belongs to the binding-protein-dependent transport system permease family
DCC27_007260	COG0215	cysteine-tRNA ligase activity
DCC27_007270	COG0745	RESPONSE REGULATOR receiver
DCC27_007275	COG5002	protein histidine kinase activity
DCC27_007280	COG0704	Plays a role in the regulation of phosphate uptake
DCC27_007295	COG0512	Glutamine amidotransferase of anthranilate synthase
DCC27_007295	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DCC27_007300	COG0588	phosphoglycerate mutase activity
DCC27_007310	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DCC27_007315	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DCC27_007330	COG0473	3-isopropylmalate dehydrogenase activity
DCC27_007390	COG2814	Major facilitator Superfamily
DCC27_007410	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
DCC27_007425	COG0745	RESPONSE REGULATOR receiver
DCC27_007430	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DCC27_007435	COG0590	tRNA wobble adenosine to inosine editing
DCC27_007450	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DCC27_007460	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DCC27_007465	COG2079	MmgE PrpD family protein
DCC27_007525	COG3547	Transposase (IS116 IS110 IS902 family)
DCC27_007530	COG0732	type I restriction modification DNA specificity domain
DCC27_007545	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DCC27_007550	COG0531	amino acid
DCC27_007560	COG1715	Restriction endonuclease
DCC27_007575	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DCC27_007580	COG1201	RNA secondary structure unwinding
DCC27_007585	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DCC27_007590	COG0564	pseudouridine synthase activity
DCC27_007605	COG2146	nitrite reductase [NAD(P)H] activity
DCC27_007615	COG0343	queuine tRNA-ribosyltransferase activity
DCC27_007645	COG2855	membrane
DCC27_007655	COG1329	Transcriptional regulator
DCC27_007665	COG0598	Magnesium transport protein CorA
DCC27_007690	COG0517	IMP dehydrogenase activity
DCC27_007690	COG4175	Glycine betaine
DCC27_007700	COG1012	belongs to the aldehyde dehydrogenase family
DCC27_007715	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DCC27_007715	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DCC27_007720	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DCC27_007760	COG0693	protein deglycase activity
DCC27_007770	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DCC27_007790	COG2197	response regulator
DCC27_007795	COG4152	abc transporter atp-binding protein
DCC27_007820	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DCC27_007830	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DCC27_007840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DCC27_007845	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
DCC27_007860	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DCC27_007890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DCC27_007925	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DCC27_007930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DCC27_007940	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DCC27_007950	COG0318	PFAM AMP-dependent synthetase and ligase
DCC27_007960	COG0477	Major facilitator Superfamily
DCC27_007985	COG1012	belongs to the aldehyde dehydrogenase family
DCC27_007995	COG0477	Major facilitator Superfamily
DCC27_008015	COG1832	CoA-binding protein
DCC27_008025	COG0028	Belongs to the TPP enzyme family
DCC27_008050	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DCC27_008055	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DCC27_008060	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DCC27_008065	COG1435	thymidine kinase activity
DCC27_008080	COG0747	negative chemotaxis
DCC27_008090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DCC27_008095	COG3547	Transposase (IS116 IS110 IS902 family)
DCC27_008170	COG0577	efflux transmembrane transporter activity
DCC27_008170	COG1136	(ABC) transporter
DCC27_008195	COG4585	Histidine kinase
DCC27_008200	COG2197	response regulator
DCC27_008235	COG2197	response regulator
DCC27_008240	COG4585	Histidine kinase
DCC27_008250	COG1131	(ABC) transporter
DCC27_008285	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DCC27_008290	COG2011	ABC-type metal ion transport system permease component
DCC27_008295	COG1464	Belongs to the NlpA lipoprotein family
DCC27_008325	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DCC27_008345	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DCC27_008355	COG0366	Alpha amylase catalytic
DCC27_008360	COG1321	iron dependent repressor
DCC27_008370	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DCC27_008375	COG0047	phosphoribosylformylglycinamidine synthase activity
DCC27_008380	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DCC27_008385	COG1024	Enoyl-CoA hydratase
DCC27_008385	COG1250	3-hydroxyacyl-CoA dehydrogenase
DCC27_008390	COG0183	Belongs to the thiolase family
DCC27_008400	COG1174	glycine betaine transport
DCC27_008405	COG0517	IMP dehydrogenase activity
DCC27_008405	COG1125	glycine betaine transport
DCC27_008420	COG0739	heme binding
DCC27_008445	COG1388	LysM domain
DCC27_008445	COG3103	Sh3 type 3 domain protein
DCC27_008445	COG0791	NLP P60 protein
DCC27_008470	COG0857	belongs to the CobB CobQ family
DCC27_008470	COG0280	phosphate acetyltransferase
DCC27_008475	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DCC27_008480	COG2733	membrane
DCC27_008505	COG5006	permease, DMT superfamily
DCC27_008545	COG0306	phosphate transporter
DCC27_008555	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DCC27_008560	COG0581	inorganic phosphate transmembrane transporter activity
DCC27_008600	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DCC27_008605	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DCC27_008615	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DCC27_008620	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DCC27_008640	COG0542	response to heat
DCC27_008655	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DCC27_008660	COG0583	DNA-binding transcription factor activity
DCC27_008700	COG3590	peptidase
DCC27_008710	COG0531	amino acid
DCC27_008735	COG0302	gtp cyclohydrolase
DCC27_008735	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DCC27_008745	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DCC27_008750	COG0302	gtp cyclohydrolase
DCC27_008765	COG0037	tRNA processing
DCC27_008780	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DCC27_008795	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DCC27_008800	COG1597	lipid kinase activity
DCC27_008805	COG0077	Prephenate dehydratase
DCC27_008810	COG0425	Belongs to the sulfur carrier protein TusA family
DCC27_008810	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DCC27_008820	COG1012	belongs to the aldehyde dehydrogenase family
DCC27_008830	COG0559	Belongs to the binding-protein-dependent transport system permease family
DCC27_008855	COG2130	NADP-dependent
DCC27_008860	COG0183	Belongs to the thiolase family
DCC27_008865	COG1024	Enoyl-CoA hydratase
DCC27_008885	COG1960	acyl-CoA dehydrogenase activity
DCC27_008890	COG1960	acyl-CoA dehydrogenase activity
DCC27_008895	COG0318	PFAM AMP-dependent synthetase and ligase
DCC27_008920	COG0604	alcohol dehydrogenase
DCC27_008955	COG0561	phosphatase activity
DCC27_008960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DCC27_008965	COG2233	PERMEase
DCC27_008980	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DCC27_009000	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DCC27_009010	COG1518	maintenance of DNA repeat elements
DCC27_009095	COG0582	viral genome integration into host DNA
DCC27_009115	COG1716	ATPase activity
DCC27_009130	COG0768	penicillin binding
DCC27_009135	COG0515	serine threonine protein kinase
DCC27_009140	COG0515	serine threonine protein kinase
DCC27_009140	COG2815	serine threonine protein kinase
DCC27_009150	COG3764	Sortase (surface protein transpeptidase)
DCC27_009175	COG2189	Belongs to the N(4) N(6)-methyltransferase family
DCC27_009205	COG1120	ATPase activity
DCC27_009210	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DCC27_009215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DCC27_009220	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DCC27_009270	COG1122	ATPase activity
DCC27_009315	COG2076	Multidrug Resistance protein
DCC27_009320	COG0590	tRNA wobble adenosine to inosine editing
DCC27_009345	COG1960	acyl-CoA dehydrogenase activity
DCC27_009350	COG0662	Cupin 2, conserved barrel domain protein
DCC27_009435	COG1780	Probably involved in ribonucleotide reductase function
DCC27_009440	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DCC27_009445	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DCC27_009450	COG0431	NADPH-dependent FMN reductase
DCC27_009470	COG3266	domain, Protein
DCC27_009475	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DCC27_009480	COG0187	DNA topoisomerase II activity
DCC27_009490	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DCC27_009500	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DCC27_009505	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DCC27_009510	COG0594	ribonuclease P activity
DCC27_009515	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DCC27_009520	COG0706	membrane insertase activity
DCC27_009530	COG0357	Ribosomal RNA small subunit methyltransferase G
DCC27_009535	COG1192	Involved in chromosome partitioning
DCC27_009550	COG0492	ferredoxin-NADP+ reductase activity
DCC27_009560	COG0728	peptidoglycan biosynthetic process
DCC27_009580	COG2759	Belongs to the formate--tetrahydrofolate ligase family
DCC27_009585	COG1260	myo-inositol-1-phosphate synthase
DCC27_009595	COG1362	aminopeptidase activity
DCC27_009600	COG0360	Binds together with S18 to 16S ribosomal RNA
DCC27_009610	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DCC27_009615	COG0359	binds to the 23S rRNA
DCC27_009630	COG0305	Participates in initiation and elongation during chromosome replication
DCC27_009640	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DCC27_009645	COG2357	RelA SpoT domain protein
DCC27_009650	COG0436	Aminotransferase
DCC27_009675	COG2226	methyltransferase
DCC27_009685	COG3949	Membrane
DCC27_009700	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DCC27_009720	COG1024	Enoyl-CoA hydratase
DCC27_009725	COG0318	PFAM AMP-dependent synthetase and ligase
DCC27_009730	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
DCC27_009770	COG1960	acyl-CoA dehydrogenase activity
DCC27_009775	COG1250	3-hydroxyacyl-CoA dehydrogenase
DCC27_009780	COG1024	Enoyl-CoA hydratase
DCC27_009790	COG1028	Short-chain dehydrogenase reductase Sdr
DCC27_009800	COG0577	efflux transmembrane transporter activity
DCC27_009800	COG1136	(ABC) transporter
DCC27_009815	COG2197	response regulator
DCC27_009820	COG4585	Histidine kinase
DCC27_009835	COG1121	(ABC) transporter
DCC27_009840	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DCC27_009860	COG0019	diaminopimelate decarboxylase activity
DCC27_009865	COG2197	response regulator
DCC27_009880	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DCC27_009890	COG1104	cysteine desulfurase activity
DCC27_009900	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DCC27_009910	COG5285	phytanoyl-CoA dioxygenase
DCC27_009915	COG1254	Belongs to the acylphosphatase family
DCC27_009920	COG1506	peptidase
DCC27_009920	COG0823	Involved in the tonB-independent uptake of proteins
DCC27_009930	COG4608	Belongs to the ABC transporter superfamily
DCC27_009935	COG0444	Belongs to the ABC transporter superfamily
DCC27_009940	COG2801	Transposase and inactivated derivatives
DCC27_009940	COG3415	Transposase
DCC27_009960	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DCC27_009970	COG1254	Belongs to the acylphosphatase family
DCC27_009975	COG0823	Involved in the tonB-independent uptake of proteins
DCC27_009975	COG1506	peptidase
DCC27_009990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DCC27_009995	COG4172	Belongs to the ABC transporter superfamily
DCC27_010005	COG1131	(ABC) transporter
DCC27_010020	COG2197	response regulator
DCC27_010025	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DCC27_010040	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DCC27_010050	COG3559	Exporter of polyketide antibiotics
DCC27_010055	COG1131	(ABC) transporter
DCC27_010060	COG1309	transcriptional regulator
DCC27_010065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DCC27_010070	COG0154	amidase activity
DCC27_010090	COG2205	protein histidine kinase activity
DCC27_010095	COG0745	RESPONSE REGULATOR receiver
DCC27_010100	COG0577	efflux transmembrane transporter activity
DCC27_010100	COG1136	(ABC) transporter
DCC27_010105	COG0577	efflux transmembrane transporter activity
DCC27_010105	COG1136	(ABC) transporter
DCC27_010120	COG1250	3-hydroxyacyl-CoA dehydrogenase
DCC27_010145	COG0318	PFAM AMP-dependent synthetase and ligase
DCC27_010165	COG2851	Citrate transporter
DCC27_010175	COG1301	dicarboxylic acid transport
DCC27_010180	COG4566	intracellular signal transduction
DCC27_010185	COG4191	Histidine kinase
DCC27_010190	COG2239	Acts as a magnesium transporter
DCC27_010195	COG1960	acyl-CoA dehydrogenase activity
DCC27_010205	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DCC27_010210	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DCC27_010220	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DCC27_010230	COG1574	metal-dependent hydrolase with the TIM-barrel fold
DCC27_010240	COG0765	amino acid transport
DCC27_010250	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DCC27_010255	COG2217	Heavy metal translocating P-type atpase
DCC27_010265	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DCC27_010270	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
DCC27_010280	COG1414	Transcriptional regulator
DCC27_010285	COG0028	Belongs to the TPP enzyme family
DCC27_010305	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DCC27_010315	COG1012	belongs to the aldehyde dehydrogenase family
DCC27_010325	COG0277	FAD linked oxidase domain protein
DCC27_010330	COG3971	2-oxopent-4-enoate hydratase activity
DCC27_010355	COG1012	belongs to the aldehyde dehydrogenase family
DCC27_010360	COG1785	Belongs to the alkaline phosphatase family
DCC27_010400	COG1063	alcohol dehydrogenase
DCC27_010410	COG0277	FAD linked oxidase domain protein
DCC27_010430	COG3415	Transposase
DCC27_010430	COG2801	Transposase and inactivated derivatives
DCC27_010490	COG3415	Transposase
DCC27_010490	COG2801	Transposase and inactivated derivatives
DCC27_010500	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DCC27_010505	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DCC27_010510	COG1802	Transcriptional regulator
DCC27_010525	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DCC27_010530	COG2079	MmgE PrpD family protein
DCC27_010545	COG1966	Carbon starvation protein
DCC27_010560	COG1414	Transcriptional regulator
DCC27_010565	COG4948	Mandelate Racemase Muconate Lactonizing
DCC27_010570	COG1028	Short-chain dehydrogenase reductase Sdr
DCC27_010580	COG4154	Belongs to the RbsD FucU family
DCC27_010590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DCC27_010600	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DCC27_010605	COG2011	ABC-type metal ion transport system permease component
DCC27_010610	COG1464	Belongs to the NlpA lipoprotein family
DCC27_010675	COG2076	Multidrug Resistance protein
DCC27_010680	COG0590	tRNA wobble adenosine to inosine editing
DCC27_010685	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DCC27_010715	COG3547	Transposase (IS116 IS110 IS902 family)
DCC27_010730	COG0028	Belongs to the TPP enzyme family
DCC27_010745	COG1268	BioY protein
DCC27_010755	COG1122	ATPase activity
DCC27_010760	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DCC27_010765	COG0667	Aldo Keto reductase
DCC27_010770	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DCC27_010775	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DCC27_010785	COG2203	Gaf domain
DCC27_010785	COG4585	Histidine kinase
DCC27_010790	COG2197	response regulator
DCC27_010795	COG0604	alcohol dehydrogenase
DCC27_010805	COG2608	mercury ion transmembrane transporter activity
DCC27_010810	COG1937	Protein conserved in bacteria
DCC27_010820	COG3573	Dehydrogenase
DCC27_010840	COG2201	protein-glutamate methylesterase activity
DCC27_010845	COG1120	ATPase activity
DCC27_010850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DCC27_010855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DCC27_010870	COG3486	L-lysine 6-monooxygenase (NADPH) activity
DCC27_010895	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DCC27_010900	COG0156	8-amino-7-oxononanoate synthase activity
DCC27_010905	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DCC27_010920	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DCC27_010940	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DCC27_010945	COG0477	Major facilitator Superfamily
DCC27_010955	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DCC27_010970	COG1950	PFAM Membrane protein of
DCC27_010975	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DCC27_010985	COG0022	dehydrogenase e1 component
DCC27_010990	COG0508	dehydrogenase complex catalyzes the overall conversion of
DCC27_011000	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DCC27_011005	COG1984	allophanate hydrolase subunit 2
DCC27_011010	COG4770	biotin carboxylase activity
DCC27_011020	COG4336	lyase activity
DCC27_011025	COG1914	H( )-stimulated, divalent metal cation uptake system
DCC27_011040	COG0137	argininosuccinate synthase activity
DCC27_011050	COG0584	glycerophosphoryl diester phosphodiesterase
DCC27_011055	COG1063	alcohol dehydrogenase
DCC27_011060	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
DCC27_011100	COG3425	synthase
DCC27_011105	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DCC27_011125	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DCC27_011145	COG0456	acetyltransferase
DCC27_011150	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DCC27_011155	COG1917	Cupin 2, conserved barrel domain protein
DCC27_011230	COG3850	Histidine kinase
DCC27_011260	COG1012	belongs to the aldehyde dehydrogenase family
DCC27_011265	COG0583	DNA-binding transcription factor activity
DCC27_011275	COG1028	Short-chain dehydrogenase reductase Sdr
DCC27_011280	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DCC27_011285	COG1396	sequence-specific DNA binding
DCC27_011310	COG0477	Major facilitator Superfamily
DCC27_011315	COG2957	Belongs to the agmatine deiminase family
DCC27_011325	COG1012	belongs to the aldehyde dehydrogenase family
DCC27_011330	COG0739	heme binding
DCC27_011345	COG1278	Cold shock
DCC27_011380	COG1176	ABC-type spermidine putrescine transport system, permease component I
DCC27_011385	COG1840	ABC-type Fe3 transport system, periplasmic component
DCC27_011395	COG0786	glutamate:sodium symporter activity
DCC27_011400	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DCC27_011425	COG4221	oxidoreductase activity
DCC27_011430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DCC27_011435	COG0435	Glutathione S-transferase
DCC27_011440	COG0252	asparaginase activity
DCC27_011445	COG3012	SEC-C Motif Domain Protein
DCC27_011460	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DCC27_011465	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DCC27_011470	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DCC27_011480	COG0776	regulation of translation
DCC27_011495	COG3336	cytochrome c oxidase
DCC27_011525	COG0679	Auxin Efflux Carrier
DCC27_011540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DCC27_011560	COG0789	Transcriptional regulator
DCC27_011615	COG0717	Belongs to the dCTP deaminase family
DCC27_011625	COG2111	Na H antiporter
DCC27_011625	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DCC27_011650	COG1320	monovalent cation:proton antiporter activity
DCC27_011660	COG1929	Belongs to the glycerate kinase type-1 family
DCC27_011665	COG2409	Drug exporters of the RND superfamily
DCC27_011675	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DCC27_011690	COG0783	Belongs to the Dps family
DCC27_011695	COG0443	Heat shock 70 kDa protein
DCC27_011700	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DCC27_011705	COG0484	heat shock protein binding
DCC27_011710	COG0789	Transcriptional regulator
DCC27_011725	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DCC27_011735	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DCC27_011750	COG0542	response to heat
DCC27_011765	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DCC27_011770	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DCC27_011795	COG0151	Belongs to the GarS family
DCC27_011800	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DCC27_011805	COG1408	metallophosphoesterase
DCC27_011820	COG0251	oxidation-reduction process
DCC27_011835	COG0733	neurotransmitter:sodium symporter activity
DCC27_011850	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DCC27_011895	COG1205	dead DEAH box helicase
DCC27_011895	COG1111	helicase
DCC27_011910	COG2890	protein-(glutamine-N5) methyltransferase activity
DCC27_011915	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DCC27_011915	COG1754	DNA topoisomerase type I activity
DCC27_011920	COG0248	Ppx GppA phosphatase
DCC27_011925	COG1082	Xylose isomerase domain protein TIM barrel
DCC27_011930	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DCC27_011935	COG0569	domain protein
DCC27_011940	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DCC27_011945	COG0123	including yeast histone deacetylase and acetoin utilization protein
DCC27_011970	COG0406	alpha-ribazole phosphatase activity
DCC27_011980	COG0785	Cytochrome C biogenesis protein
DCC27_011990	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DCC27_012020	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DCC27_012030	COG2814	Major facilitator Superfamily
DCC27_012035	COG1748	Saccharopine dehydrogenase
DCC27_012045	COG2252	PERMEase
DCC27_012055	COG4948	Mandelate Racemase Muconate Lactonizing
DCC27_012060	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)