locus-tag	class	description
EIA51_00020	COG3039	Transposase
EIA51_00070	COG0305	Participates in initiation and elongation during chromosome replication
EIA51_00095	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
EIA51_00100	COG1194	a g-specific adenine glycosylase
EIA51_00105	COG4213	ABC transporter substrate-binding protein
EIA51_00110	COG1129	ABC transporter
EIA51_00115	COG4214	carbohydrate transport
EIA51_00130	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EIA51_00155	COG1028	Short-chain dehydrogenase reductase Sdr
EIA51_00160	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
EIA51_00165	COG1349	DNA-binding transcription factor activity
EIA51_00180	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EIA51_00185	COG1757	Na H antiporter
EIA51_00190	COG0436	Aminotransferase
EIA51_00195	COG2115	Belongs to the xylose isomerase family
EIA51_00200	COG1070	Carbohydrate kinase
EIA51_00205	COG2207	Transcriptional regulator
EIA51_00205	COG1609	Transcriptional regulator
EIA51_00260	COG2095	MarC family integral membrane protein
EIA51_00265	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EIA51_00270	COG1114	Component of the transport system for branched-chain amino acids
EIA51_00275	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EIA51_00285	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EIA51_00300	COG3956	TIGRFAM MazG family protein
EIA51_00310	COG0583	DNA-binding transcription factor activity
EIA51_00320	COG3119	arylsulfatase activity
EIA51_00325	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EIA51_00360	COG0019	diaminopimelate decarboxylase activity
EIA51_00410	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
EIA51_00415	COG2195	Cleaves the N-terminal amino acid of tripeptides
EIA51_00435	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EIA51_00440	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EIA51_00450	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EIA51_00455	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EIA51_00475	COG0357	Ribosomal RNA small subunit methyltransferase G
EIA51_00485	COG0716	FMN binding
EIA51_00490	COG3074	FtsZ-dependent cytokinesis
EIA51_00495	COG1494	fructose-1,6-bisphosphatase
EIA51_00500	COG0187	DNA topoisomerase II activity
EIA51_00510	COG4988	ABC transporter
EIA51_00515	COG1132	(ABC) transporter
EIA51_00520	COG1858	cytochrome C peroxidase
EIA51_00530	COG0733	neurotransmitter:sodium symporter activity
EIA51_00545	COG0551	DNA topoisomerase type I activity
EIA51_00565	COG3070	regulator of competence-specific genes
EIA51_00595	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EIA51_00625	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EIA51_00635	COG1841	ribosomal large subunit assembly
EIA51_00645	COG0201	protein transport
EIA51_00655	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EIA51_00660	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EIA51_00665	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EIA51_00670	COG0202	RNA polymerase activity
EIA51_00675	COG0203	ribosomal protein L17
EIA51_00685	COG2960	long-chain fatty acid transporting porin activity
EIA51_00690	COG3172	ATPase kinase involved in NAD metabolism
EIA51_00695	COG2129	metallophosphoesterase
EIA51_00705	COG0582	viral genome integration into host DNA
EIA51_00775	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EIA51_00795	COG0732	type I restriction modification DNA specificity domain
EIA51_00805	COG3056	Lipoprotein
EIA51_00810	COG0271	Belongs to the BolA IbaG family
EIA51_00825	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EIA51_00830	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EIA51_00835	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EIA51_00845	COG1477	protein flavinylation
EIA51_00850	COG2991	Protein conserved in bacteria
EIA51_00860	COG1519	Transferase
EIA51_00870	COG0786	glutamate:sodium symporter activity
EIA51_00900	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EIA51_00910	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EIA51_00915	COG3068	Protein conserved in bacteria
EIA51_00925	COG1349	DNA-binding transcription factor activity
EIA51_00930	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EIA51_00940	COG0259	pyridoxamine-phosphate oxidase activity
EIA51_00945	COG2814	Major facilitator Superfamily
EIA51_00950	COG1763	Mo-molybdopterin cofactor biosynthetic process
EIA51_00955	COG3086	response to oxidative stress
EIA51_00960	COG3026	antisigma factor binding
EIA51_00965	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
EIA51_00970	COG1595	DNA-templated transcription, initiation
EIA51_00985	COG2226	methyltransferase
EIA51_01010	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EIA51_01015	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EIA51_01020	COG0493	'glutamate synthase
EIA51_01025	COG0069	glutamate synthase activity
EIA51_01025	COG0067	glutamate synthase
EIA51_01025	COG0070	glutamate synthase
EIA51_01035	COG0859	PFAM glycosyl transferase family 9
EIA51_01050	COG0549	Belongs to the carbamate kinase family
EIA51_01060	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EIA51_01070	COG1304	FMN binding
EIA51_01075	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EIA51_01080	COG1335	isochorismatase
EIA51_01085	COG0583	DNA-binding transcription factor activity
EIA51_01095	COG1304	FMN binding
EIA51_01100	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EIA51_01105	COG0666	response to abiotic stimulus
EIA51_01115	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EIA51_01125	COG1943	Transposase
EIA51_01130	COG0675	Transposase, IS605 OrfB family
EIA51_01140	COG1126	abc transporter atp-binding protein
EIA51_01145	COG0765	amino acid transport
EIA51_01150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EIA51_01155	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EIA51_01165	COG3078	GTPase activator activity
EIA51_01170	COG0564	pseudouridine synthase activity
EIA51_01180	COG3201	nicotinamide mononucleotide transporter
EIA51_01185	COG0673	inositol 2-dehydrogenase activity
EIA51_01190	COG3676	manually curated
EIA51_01200	COG3718	enzyme involved in inositol metabolism
EIA51_01215	COG0456	acetyltransferase
EIA51_01245	COG0738	Major facilitator superfamily
EIA51_01250	COG0235	Class ii aldolase
EIA51_01260	COG1070	Carbohydrate kinase
EIA51_01265	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
EIA51_01270	COG1349	DNA-binding transcription factor activity
EIA51_01280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EIA51_01295	COG0859	PFAM glycosyl transferase family 9
EIA51_01325	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EIA51_01335	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EIA51_01350	COG3691	Protein conserved in bacteria
EIA51_01355	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EIA51_01360	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
EIA51_01365	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
EIA51_01370	COG0363	glucosamine-6-phosphate deaminase activity
EIA51_01375	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EIA51_01380	COG1218	3'(2'),5'-bisphosphate nucleotidase
EIA51_01390	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EIA51_01395	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EIA51_01400	COG1609	Transcriptional regulator
EIA51_01405	COG1917	Cupin 2, conserved barrel domain protein
EIA51_01420	COG1129	ABC transporter
EIA51_01425	COG1172	Belongs to the binding-protein-dependent transport system permease family
EIA51_01430	COG1879	ABC-type sugar transport system periplasmic component
EIA51_01435	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EIA51_01445	COG0051	transcription antitermination factor activity, RNA binding
EIA51_01455	COG0088	Forms part of the polypeptide exit tunnel
EIA51_01465	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EIA51_01470	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EIA51_01480	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EIA51_01500	COG0582	viral genome integration into host DNA
EIA51_01585	COG3728	DNA packaging
EIA51_01655	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EIA51_01660	COG0594	ribonuclease P activity
EIA51_01665	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EIA51_01670	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EIA51_01675	COG0592	DNA-directed DNA polymerase activity
EIA51_01685	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EIA51_01690	COG1381	Involved in DNA repair and RecF pathway recombination
EIA51_01695	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EIA51_01700	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EIA51_01705	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EIA51_01710	COG0252	asparaginase activity
EIA51_01720	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EIA51_01740	COG3133	Outer membrane lipoprotein
EIA51_01745	COG3962	Belongs to the TPP enzyme family
EIA51_01755	COG0673	inositol 2-dehydrogenase activity
EIA51_01765	COG0431	NADPH-dependent FMN reductase
EIA51_01775	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EIA51_01785	COG1216	Glycosyl transferase, family 2
EIA51_01790	COG3307	-O-antigen
EIA51_01795	COG2976	Protein conserved in bacteria
EIA51_01805	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EIA51_01810	COG1426	Protein conserved in bacteria
EIA51_01815	COG0471	metal ion transport
EIA51_01815	COG0490	domain, Protein
EIA51_01820	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EIA51_01830	COG4589	Belongs to the CDS family
EIA51_01835	COG0521	Mo-molybdopterin cofactor biosynthetic process
EIA51_01845	COG0628	permease
EIA51_01855	COG3063	Type IV pilus biogenesis stability protein PilW
EIA51_01860	COG0758	DNA mediated transformation
EIA51_01865	COG0742	ribosomal rna small subunit methyltransferase
EIA51_01870	COG0552	protein localization to endoplasmic reticulum
EIA51_01875	COG0584	glycerophosphoryl diester phosphodiesterase
EIA51_01885	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EIA51_01895	COG0247	lactate metabolic process
EIA51_01900	COG1349	DNA-binding transcription factor activity
EIA51_01905	COG0705	Rhomboid family
EIA51_01915	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EIA51_01925	COG0546	phosphoglycolate phosphatase activity
EIA51_01930	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EIA51_01940	COG0251	oxidation-reduction process
EIA51_01955	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EIA51_01965	COG0512	Glutamine amidotransferase of anthranilate synthase
EIA51_01970	COG0783	Belongs to the Dps family
EIA51_01985	COG0196	riboflavin kinase activity
EIA51_02010	COG0745	RESPONSE REGULATOR receiver
EIA51_02015	COG0642	Histidine kinase
EIA51_02025	COG0165	Argininosuccinate lyase
EIA51_02030	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EIA51_02195	COG3566	protein conserved in bacteria
EIA51_02205	COG2369	cell adhesion
EIA51_02210	COG3567	Phage-associated protein, HI1409 family
EIA51_02215	COG1783	phage Terminase large subunit
EIA51_02220	COG3728	DNA packaging
EIA51_02280	COG1846	Transcriptional regulator
EIA51_02420	COG0629	single-stranded DNA binding
EIA51_02445	COG3617	BRO family, N-terminal domain
EIA51_02460	COG0582	viral genome integration into host DNA
EIA51_02490	COG0752	glycyl-tRNA synthetase alpha subunit
EIA51_02495	COG4545	Glutaredoxin-related protein
EIA51_02505	COG4804	nuclease activity
EIA51_02510	COG2852	Protein conserved in bacteria
EIA51_02530	COG1017	nitric oxide dioxygenase activity
EIA51_02530	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EIA51_02535	COG3676	manually curated
EIA51_02540	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EIA51_02545	COG4972	Pilus assembly protein
EIA51_02565	COG4796	Type ii and iii secretion system protein
EIA51_02575	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EIA51_02580	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EIA51_02585	COG4701	Protein of unknown function (DUF721)
EIA51_02595	COG0653	protein targeting
EIA51_02600	COG0494	nUDIX hydrolase
EIA51_02605	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EIA51_02630	COG0582	viral genome integration into host DNA
EIA51_02655	COG2026	Addiction module toxin, RelE StbE family
EIA51_02715	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EIA51_02735	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EIA51_02735	COG1328	CTP reductase activity
EIA51_02745	COG0602	queuosine metabolic process
EIA51_02750	COG0084	hydrolase, TatD family'
EIA51_02760	COG0805	protein transport
EIA51_02765	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EIA51_02775	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EIA51_02785	COG2226	methyltransferase
EIA51_02790	COG0471	metal ion transport
EIA51_02795	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EIA51_02800	COG1575	Belongs to the MenA family. Type 1 subfamily
EIA51_02805	COG1720	tRNA m6t6A37 methyltransferase activity
EIA51_02810	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EIA51_02815	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EIA51_02820	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EIA51_02825	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EIA51_02855	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EIA51_02860	COG1879	ABC-type sugar transport system periplasmic component
EIA51_02865	COG1879	ABC-type sugar transport system periplasmic component
EIA51_02870	COG1129	ABC transporter
EIA51_02875	COG1172	Belongs to the binding-protein-dependent transport system permease family
EIA51_02900	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EIA51_02910	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EIA51_02915	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EIA51_02920	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EIA51_02925	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EIA51_02930	COG1737	Transcriptional regulator
EIA51_02935	COG2731	YhcH YjgK YiaL family protein
EIA51_02945	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
EIA51_02955	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EIA51_02975	COG4771	TonB-dependent receptor
EIA51_02980	COG3721	Heme iron utilization protein
EIA51_02985	COG0748	coenzyme F420 binding
EIA51_02990	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EIA51_02995	COG1792	Involved in formation and maintenance of cell shape
EIA51_03000	COG1077	Cell shape determining protein MreB Mrl
EIA51_03070	COG0656	L-ascorbic acid biosynthetic process
EIA51_03080	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EIA51_03095	COG1028	Short-chain dehydrogenase reductase Sdr
EIA51_03100	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EIA51_03105	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EIA51_03110	COG0416	fatty acid biosynthetic process
EIA51_03115	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EIA51_03120	COG1399	metal-binding, possibly nucleic acid-binding protein
EIA51_03125	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EIA51_03130	COG0500	methyltransferase
EIA51_03135	COG2830	Protein of unknown function (DUF452)
EIA51_03145	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EIA51_03165	COG0545	Peptidyl-prolyl cis-trans isomerase
EIA51_03170	COG3676	manually curated
EIA51_03175	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EIA51_03180	COG0194	GDP metabolic process
EIA51_03190	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EIA51_03195	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EIA51_03225	COG3842	ATPase activity
EIA51_03235	COG0572	uridine kinase
EIA51_03255	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EIA51_03260	COG0513	Belongs to the DEAD box helicase family
EIA51_03265	COG0799	negative regulation of ribosome biogenesis
EIA51_03275	COG0768	penicillin binding
EIA51_03280	COG0772	Belongs to the SEDS family
EIA51_03290	COG1686	Belongs to the peptidase S11 family
EIA51_03300	COG0321	lipoyl(octanoyl) transferase activity
EIA51_03310	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
EIA51_03315	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
EIA51_03320	COG0437	4 iron, 4 sulfur cluster binding
EIA51_03325	COG3301	Polysulphide reductase, NrfD
EIA51_03335	COG2081	HI0933 family
EIA51_03340	COG3088	subunit of a heme lyase
EIA51_03340	COG4235	cytochrome complex assembly
EIA51_03345	COG4235	cytochrome complex assembly
EIA51_03345	COG3088	subunit of a heme lyase
EIA51_03360	COG1760	l-serine dehydratase
EIA51_03365	COG0814	amino acid
EIA51_03370	COG0121	glutamine amidotransferase
EIA51_03380	COG0204	Acyl-transferase
EIA51_03390	COG1702	phosphate starvation-inducible protein PhoH
EIA51_03395	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EIA51_03400	COG1444	tRNA N-acetyltransferase activity
EIA51_03415	COG3116	cell division
EIA51_03430	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EIA51_03440	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EIA51_03465	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EIA51_03470	COG0849	cell division
EIA51_03475	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EIA51_03480	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EIA51_03495	COG4221	oxidoreductase activity
EIA51_03510	COG3321	synthase
EIA51_03510	COG1028	Short-chain dehydrogenase reductase Sdr
EIA51_03510	COG0604	alcohol dehydrogenase
EIA51_03515	COG0077	Prephenate dehydratase
EIA51_03515	COG1605	Chorismate mutase
EIA51_03520	COG4974	Belongs to the 'phage' integrase family
EIA51_03525	COG2814	Major facilitator Superfamily
EIA51_03530	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EIA51_03540	COG3266	domain, Protein
EIA51_03540	COG3061	Opacity-associated protein A
EIA51_03545	COG1509	lysine 2,3-aminomutase activity
EIA51_03570	COG1177	transmembrane transport
EIA51_03580	COG3842	ATPase activity
EIA51_03585	COG0584	glycerophosphoryl diester phosphodiesterase
EIA51_03590	COG0800	Aldolase
EIA51_03595	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EIA51_03605	COG1028	Short-chain dehydrogenase reductase Sdr
EIA51_03615	COG3119	arylsulfatase activity
EIA51_03625	COG2222	sugar isomerase
EIA51_03630	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EIA51_03635	COG3715	PTS system
EIA51_03640	COG3716	PTS system mannose fructose sorbose family IID component
EIA51_03645	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EIA51_03645	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EIA51_03650	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EIA51_03660	COG0641	radical SAM
EIA51_03665	COG3119	arylsulfatase activity
EIA51_03680	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EIA51_03685	COG3684	Belongs to the aldolase LacD family
EIA51_03700	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EIA51_03705	COG2391	methyltransferase activity
EIA51_03710	COG2897	thiosulfate sulfurtransferase activity
EIA51_03715	COG0527	aspartate kinase activity
EIA51_03725	COG2860	membrane
EIA51_03735	COG2067	long-chain fatty acid transport protein
EIA51_03740	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EIA51_03745	COG3066	DNA modification
EIA51_03750	COG0861	Integral membrane protein TerC family
EIA51_03770	COG0436	Aminotransferase
EIA51_03785	COG2267	carboxylic ester hydrolase activity
EIA51_03835	COG1028	Short-chain dehydrogenase reductase Sdr
EIA51_03850	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EIA51_03865	COG2186	Transcriptional regulator
EIA51_03875	COG1660	Displays ATPase and GTPase activities
EIA51_03880	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EIA51_03885	COG1137	ATPase activity
EIA51_03890	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EIA51_03895	COG3117	lipopolysaccharide transmembrane transporter activity
EIA51_03905	COG1127	ABC transporter
EIA51_03915	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EIA51_03920	COG2854	intermembrane phospholipid transfer
EIA51_03925	COG3113	response to antibiotic
EIA51_03930	COG5007	Belongs to the BolA IbaG family
EIA51_03935	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EIA51_03940	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EIA51_03945	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EIA51_03950	COG1278	Cold shock
EIA51_03965	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
EIA51_03970	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EIA51_03975	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
EIA51_03985	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
EIA51_03995	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EIA51_04000	COG1053	succinate dehydrogenase
EIA51_04005	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EIA51_04010	COG0339	signal peptide processing
EIA51_04015	COG2832	Protein of unknown function (DUF454)
EIA51_04020	COG4166	transmembrane transport
EIA51_04030	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EIA51_04040	COG0316	Belongs to the HesB IscA family
EIA51_04045	COG0024	Methionine aminopeptidase
EIA51_04055	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EIA51_04115	COG1530	ribonuclease E activity
EIA51_04140	COG2965	DNA replication, synthesis of RNA primer
EIA51_04145	COG0360	Binds together with S18 to 16S ribosomal RNA
EIA51_04150	COG0497	DNA recombination
EIA51_04160	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EIA51_04165	COG1846	Transcriptional regulator
EIA51_04165	COG1940	carbohydrate kinase activity
EIA51_04195	COG0330	HflC and HflK could
EIA51_04205	COG2249	NAD(P)H dehydrogenase (quinone) activity
EIA51_04210	COG3381	protein complex oligomerization
EIA51_04215	COG0372	Belongs to the citrate synthase family
EIA51_04220	COG0567	Dehydrogenase, E1 component
EIA51_04225	COG0508	dehydrogenase complex catalyzes the overall conversion of
EIA51_04235	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EIA51_04240	COG0037	tRNA processing
EIA51_04250	COG0778	Nitroreductase
EIA51_04255	COG0469	pyruvate kinase activity
EIA51_04265	COG2964	Protein conserved in bacteria
EIA51_04270	COG0814	amino acid
EIA51_04280	COG4774	siderophore transport
EIA51_04290	COG5266	PFAM Nickel transport complex, NikM subunit, transmembrane
EIA51_04305	COG1120	ATPase activity
EIA51_04310	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
EIA51_04315	COG2824	Alkylphosphonate utilization operon protein PhnA
EIA51_04325	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EIA51_04325	COG2885	chlorophyll binding
EIA51_04330	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EIA51_04335	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EIA51_04340	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EIA51_04350	COG3177	Filamentation induced by cAMP protein fic
EIA51_04365	COG0676	glucose-6-phosphate 1-epimerase activity
EIA51_04370	COG1136	(ABC) transporter
EIA51_04380	COG1136	(ABC) transporter
EIA51_04380	COG0577	efflux transmembrane transporter activity
EIA51_04395	COG0672	)-iron permease
EIA51_04400	COG0489	protein tyrosine kinase activity
EIA51_04405	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EIA51_04405	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EIA51_04410	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EIA51_04410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EIA51_04415	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EIA51_04420	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EIA51_04425	COG5039	Polysaccharide pyruvyl transferase
EIA51_04435	COG3306	glycosyltransferase involved in LPS biosynthesis
EIA51_04445	COG1216	Glycosyl transferase, family 2
EIA51_04450	COG1216	Glycosyl transferase, family 2
EIA51_04455	COG2951	lytic endotransglycosylase activity
EIA51_04460	COG1741	Belongs to the pirin family
EIA51_04475	COG2378	regulation of single-species biofilm formation
EIA51_04510	COG4735	regulation of single-species biofilm formation
EIA51_04535	COG3099	Belongs to the UPF0263 family
EIA51_04545	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EIA51_04550	COG1923	regulation of RNA biosynthetic process
EIA51_04560	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EIA51_04565	COG0860	N-Acetylmuramoyl-L-alanine amidase
EIA51_04565	COG1388	LysM domain
EIA51_04570	COG0802	atpase or kinase
EIA51_04585	COG1621	beta-fructofuranosidase activity
EIA51_04595	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EIA51_04610	COG2089	acid synthase
EIA51_04620	COG3119	arylsulfatase activity
EIA51_04635	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EIA51_04640	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EIA51_04650	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EIA51_04660	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EIA51_04665	COG0745	RESPONSE REGULATOR receiver
EIA51_04670	COG0642	Histidine kinase
EIA51_04675	COG0583	DNA-binding transcription factor activity
EIA51_04685	COG2189	Belongs to the N(4) N(6)-methyltransferase family
EIA51_04710	COG3210	domain, Protein
EIA51_04720	COG3210	domain, Protein
EIA51_04735	COG2814	Major facilitator Superfamily
EIA51_04740	COG4221	oxidoreductase activity
EIA51_04755	COG0741	lytic transglycosylase activity
EIA51_04760	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EIA51_04765	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EIA51_04770	COG1862	Preprotein translocase
EIA51_04775	COG3945	hemerythrin HHE cation binding domain
EIA51_04790	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EIA51_04795	COG0506	proline dehydrogenase activity
EIA51_04795	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EIA51_04795	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EIA51_04800	COG2056	Na+-H+ antiporter family
EIA51_04805	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EIA51_04810	COG0346	lactoylglutathione lyase activity
EIA51_04820	COG0460	homoserine dehydrogenase
EIA51_04820	COG0527	aspartate kinase activity
EIA51_04825	COG0083	homoserine kinase activity
EIA51_04830	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EIA51_04850	COG1393	Belongs to the ArsC family
EIA51_04855	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EIA51_04860	COG1876	peptidase activity
EIA51_04870	COG0494	nUDIX hydrolase
EIA51_04875	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EIA51_04900	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EIA51_04905	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EIA51_04925	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EIA51_04940	COG1757	Na H antiporter
EIA51_04945	COG0028	Belongs to the TPP enzyme family
EIA51_04950	COG0440	acetolactate synthase activity
EIA51_04955	COG0039	L-malate dehydrogenase activity
EIA51_04975	COG0778	Nitroreductase
EIA51_04980	COG0616	signal peptide processing
EIA51_04985	COG0583	DNA-binding transcription factor activity
EIA51_05010	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EIA51_05015	COG1328	CTP reductase activity
EIA51_05020	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EIA51_05030	COG0187	DNA topoisomerase II activity
EIA51_05035	COG3008	intermembrane lipid transfer
EIA51_05040	COG2995	paraquat-inducible protein a
EIA51_05045	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
EIA51_05050	COG0793	Belongs to the peptidase S41A family
EIA51_05055	COG2989	Protein conserved in bacteria
EIA51_05060	COG3108	Peptidase M15
EIA51_05065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EIA51_05070	COG1560	Kdo2-lipid A biosynthetic process
EIA51_05075	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
EIA51_05075	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EIA51_05080	COG3100	YcgL domain-containing protein
EIA51_05085	COG0450	alkyl hydroperoxide reductase
EIA51_05105	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EIA51_05110	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EIA51_05125	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EIA51_05130	COG0583	DNA-binding transcription factor activity
EIA51_05150	COG0210	DNA helicase
EIA51_05155	COG2823	Periplasmic or secreted lipoprotein
EIA51_05160	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EIA51_05165	COG0792	nuclease activity
EIA51_05180	COG0009	L-threonylcarbamoyladenylate synthase
EIA51_05190	COG0583	DNA-binding transcription factor activity
EIA51_05195	COG2171	N-acyltransferase activity
EIA51_05205	COG0589	response to stress
EIA51_05210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EIA51_05215	COG1528	Iron-storage protein
EIA51_05220	COG1528	Iron-storage protein
EIA51_05225	COG2431	L-lysine efflux transmembrane transporter activity
EIA51_05230	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EIA51_05235	COG0303	'Molybdopterin
EIA51_05245	COG1696	Membrane protein involved in D-alanine export
EIA51_05290	COG0315	cyclic pyranopterin monophosphate synthase activity
EIA51_05295	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EIA51_05300	COG0314	molybdopterin synthase activity
EIA51_05305	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
EIA51_05315	COG1289	transmembrane transporter activity
EIA51_05325	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EIA51_05345	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EIA51_05350	COG4591	ABC-type transport system involved in lipoprotein release permease component
EIA51_05360	COG4591	ABC-type transport system involved in lipoprotein release permease component
EIA51_05365	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EIA51_05370	COG1609	Transcriptional regulator
EIA51_05375	COG2949	membrane
EIA51_05380	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EIA51_05385	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EIA51_05390	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EIA51_05395	COG1121	(ABC) transporter
EIA51_05405	COG2920	part of a sulfur-relay system
EIA51_05410	COG0670	Belongs to the BI1 family
EIA51_05415	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EIA51_05425	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EIA51_05430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EIA51_05445	COG2195	Cleaves the N-terminal amino acid of tripeptides
EIA51_05450	COG0488	(ABC) transporter
EIA51_05455	COG3683	transport system, periplasmic component
EIA51_05460	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
EIA51_05480	COG3306	glycosyltransferase involved in LPS biosynthesis
EIA51_05490	COG3306	glycosyltransferase involved in LPS biosynthesis
EIA51_05510	COG0582	viral genome integration into host DNA
EIA51_05515	COG1476	TRANSCRIPTIONal
EIA51_05545	COG2999	glutathione oxidoreductase activity
EIA51_05580	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EIA51_05585	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EIA51_05585	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EIA51_05590	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EIA51_05600	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EIA51_05610	COG2062	phosphohistidine phosphatase, SixA
EIA51_05620	COG0814	amino acid
EIA51_05625	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EIA51_05630	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EIA51_05635	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EIA51_05640	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EIA51_05645	COG1280	lysine exporter protein (LysE YggA)
EIA51_05655	COG0633	Ferredoxin
EIA51_05670	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EIA51_05675	COG3105	Protein conserved in bacteria
EIA51_05680	COG1944	ATP diphosphatase activity
EIA51_05685	COG2226	methyltransferase
EIA51_05690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EIA51_05695	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EIA51_05715	COG0795	lipopolysaccharide-transporting ATPase activity
EIA51_05720	COG0795	lipopolysaccharide-transporting ATPase activity
EIA51_05725	COG0668	transmembrane transport
EIA51_05750	COG0280	phosphate acetyltransferase
EIA51_05750	COG0857	belongs to the CobB CobQ family
EIA51_05760	COG3092	negative regulation of chromosome organization
EIA51_05765	COG1286	toxin biosynthetic process
EIA51_05775	COG0163	prenyltransferase activity
EIA51_05820	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EIA51_05825	COG0308	aminopeptidase N
EIA51_05830	COG0167	dihydroorotate dehydrogenase activity
EIA51_05835	COG0613	PHP domain protein
EIA51_05840	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EIA51_05845	COG0287	Prephenate dehydrogenase
EIA51_05845	COG1605	Chorismate mutase
EIA51_05855	COG3217	Mosc domain protein beta barrel domain protein
EIA51_05855	COG0633	Ferredoxin
EIA51_05865	COG1534	Rna-binding protein
EIA51_05885	COG0301	tRNA thio-modification
EIA51_05885	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EIA51_05890	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EIA51_05895	COG0617	tRNA 3'-terminal CCA addition
EIA51_05900	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EIA51_05910	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EIA51_05910	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EIA51_05915	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EIA51_05930	COG2268	Band 7 protein
EIA51_05935	COG2166	iron-sulfur cluster assembly
EIA51_05945	COG1525	nuclease
EIA51_05950	COG1380	Effector of murein hydrolase LrgA
EIA51_05955	COG1346	cytolysis
EIA51_05965	COG1522	sequence-specific DNA binding
EIA51_05995	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EIA51_06015	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EIA51_06020	COG1162	GTPase activity
EIA51_06025	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EIA51_06030	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EIA51_06035	COG2190	(PTS) system
EIA51_06040	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EIA51_06045	COG0508	dehydrogenase complex catalyzes the overall conversion of
EIA51_06050	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EIA51_06060	COG1538	Outer membrane efflux protein
EIA51_06065	COG0577	efflux transmembrane transporter activity
EIA51_06065	COG1136	(ABC) transporter
EIA51_06085	COG3152	Membrane
EIA51_06090	COG1640	4-alpha-glucanotransferase
EIA51_06095	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EIA51_06125	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EIA51_06135	COG3101	peptidyl-lysine hydroxylation
EIA51_06145	COG0842	Transport permease protein
EIA51_06150	COG1215	transferase activity, transferring glycosyl groups
EIA51_06160	COG4453	Protein conserved in bacteria
EIA51_06165	COG1611	Belongs to the LOG family
EIA51_06170	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EIA51_06170	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EIA51_06180	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
EIA51_06185	COG3098	single-species biofilm formation
EIA51_06195	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EIA51_06210	COG2969	positive regulation of protein catabolic process
EIA51_06230	COG2925	Exonuclease
EIA51_06235	COG0697	spore germination
EIA51_06265	COG0791	NLP P60 protein
EIA51_06270	COG0776	regulation of translation
EIA51_06285	COG0564	pseudouridine synthase activity
EIA51_06295	COG0406	alpha-ribazole phosphatase activity
EIA51_06300	COG0788	formyltetrahydrofolate deformylase activity
EIA51_06310	COG1846	Transcriptional regulator
EIA51_06310	COG1940	carbohydrate kinase activity
EIA51_06335	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EIA51_06340	COG1074	ATP-dependent DNA helicase activity
EIA51_06345	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
EIA51_06350	COG2252	PERMEase
EIA51_06355	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EIA51_06360	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EIA51_06370	COG1067	ATP-dependent peptidase activity
EIA51_06385	COG1609	Transcriptional regulator
EIA51_06400	COG1278	Cold shock
EIA51_06405	COG3140	Belongs to the UPF0181 family
EIA51_06410	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EIA51_06415	COG0285	dihydrofolate synthase activity
EIA51_06445	COG0517	IMP dehydrogenase activity
EIA51_06445	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EIA51_06450	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EIA51_06460	COG0039	L-malate dehydrogenase activity
EIA51_06465	COG1438	arginine binding
EIA51_06470	COG1090	epimerase
EIA51_06475	COG4657	Part of a membrane complex involved in electron transport
EIA51_06485	COG4656	Part of a membrane complex involved in electron transport
EIA51_06490	COG4658	electron transport chain
EIA51_06505	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EIA51_06510	COG0733	neurotransmitter:sodium symporter activity
EIA51_06520	COG3265	gluconokinase activity
EIA51_06525	COG2610	gluconate transmembrane transporter activity
EIA51_06530	COG3118	belongs to the thioredoxin family
EIA51_06535	COG0492	ferredoxin-NADP+ reductase activity
EIA51_06540	COG4988	ABC transporter
EIA51_06545	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EIA51_06560	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EIA51_06565	COG0318	PFAM AMP-dependent synthetase and ligase
EIA51_06570	COG1214	PFAM Peptidase M22, glycoprotease
EIA51_06575	COG1199	ATP-dependent helicase activity
EIA51_06585	COG2863	cytochrome
EIA51_06590	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EIA51_06595	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EIA51_06600	COG1408	metallophosphoesterase
EIA51_06610	COG0616	signal peptide processing
EIA51_06625	COG0708	Exodeoxyribonuclease III
EIA51_06635	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EIA51_06650	COG1914	H( )-stimulated, divalent metal cation uptake system
EIA51_06655	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EIA51_06660	COG1984	allophanate hydrolase subunit 2
EIA51_06665	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EIA51_06670	COG3955	Domain of unknown function (DUF1919)
EIA51_06675	COG0617	tRNA 3'-terminal CCA addition
EIA51_06680	COG4991	sh3 domain protein
EIA51_06725	COG1704	LemA family
EIA51_06735	COG0247	lactate metabolic process
EIA51_06735	COG0277	FAD linked oxidase domain protein
EIA51_06750	COG3047	cAMP biosynthetic process
EIA51_06760	COG2917	probably involved in intracellular septation
EIA51_06765	COG1607	acyl-coa hydrolase
EIA51_06770	COG2350	Protein conserved in bacteria
EIA51_06780	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EIA51_06785	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EIA51_06790	COG1566	PFAM secretion protein HlyD family protein
EIA51_06800	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EIA51_06805	COG0195	Participates in both transcription termination and antitermination
EIA51_06820	COG0515	serine threonine protein kinase
EIA51_06840	COG1940	carbohydrate kinase activity
EIA51_06845	COG0671	phosphoesterase, PA-phosphatase related
EIA51_06850	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EIA51_06870	COG0307	riboflavin synthase, alpha
EIA51_06880	COG0673	inositol 2-dehydrogenase activity
EIA51_06885	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EIA51_06890	COG0586	Pfam SNARE associated Golgi protein
EIA51_06900	COG1116	anion transmembrane transporter activity
EIA51_06905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EIA51_06910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EIA51_06915	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EIA51_06920	COG2835	tetraacyldisaccharide 4'-kinase activity
EIA51_06925	COG1663	tetraacyldisaccharide 4'-kinase activity
EIA51_06930	COG1132	(ABC) transporter
EIA51_06935	COG2333	competence protein COMEC
EIA51_06935	COG0658	competence protein
EIA51_06945	COG0351	phosphomethylpyrimidine kinase
EIA51_06950	COG0352	thiamine-phosphate diphosphorylase activity
EIA51_06960	COG3468	outer membrane autotransporter barrel domain protein
EIA51_06960	COG3266	domain, Protein
EIA51_06965	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EIA51_06970	COG3025	triphosphatase activity
EIA51_06975	COG1392	Phosphate transport regulator
EIA51_06980	COG0306	phosphate transporter
EIA51_06985	COG0288	reversible hydration of carbon dioxide
EIA51_06990	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EIA51_06995	COG1448	Aminotransferase
EIA51_07000	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EIA51_07005	COG3835	regulator
EIA51_07010	COG2610	gluconate transmembrane transporter activity
EIA51_07015	COG1929	Belongs to the glycerate kinase type-1 family
EIA51_07025	COG0632	four-way junction helicase activity
EIA51_07040	COG0494	nUDIX hydrolase
EIA51_07050	COG3041	Addiction module toxin RelE StbE family
EIA51_07055	COG3077	Addiction module antitoxin, RelB DinJ family
EIA51_07085	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
EIA51_07090	COG2932	Transcriptional regulator
EIA51_07115	COG0305	Participates in initiation and elongation during chromosome replication
EIA51_07130	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EIA51_07135	COG4149	molybdate abc transporter
EIA51_07140	COG0725	ABC transporter, periplasmic molybdate-binding protein
EIA51_07145	COG2005	Transcriptional regulator
EIA51_07150	COG0786	glutamate:sodium symporter activity
EIA51_07165	COG0730	response to heat
EIA51_07170	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EIA51_07180	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
EIA51_07185	COG1178	ABC-type Fe3 transport system permease component
EIA51_07190	COG4143	(ABC) transporter
EIA51_07200	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EIA51_07210	COG3842	ATPase activity
EIA51_07215	COG1176	ABC-type spermidine putrescine transport system, permease component I
EIA51_07220	COG1177	transmembrane transport
EIA51_07225	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EIA51_07235	COG1733	regulation of RNA biosynthetic process
EIA51_07240	COG0281	malic enzyme
EIA51_07250	COG0673	inositol 2-dehydrogenase activity
EIA51_07260	COG1175	transmembrane transport
EIA51_07270	COG3842	ATPase activity
EIA51_07275	COG2186	Transcriptional regulator
EIA51_07280	COG0673	inositol 2-dehydrogenase activity
EIA51_07285	COG1966	Carbon starvation protein
EIA51_07290	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EIA51_07295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EIA51_07300	COG1560	Kdo2-lipid A biosynthetic process
EIA51_07305	COG0730	response to heat
EIA51_07310	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
EIA51_07320	COG3264	Mechanosensitive ion channel
EIA51_07320	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
EIA51_07325	COG0318	PFAM AMP-dependent synthetase and ligase
EIA51_07330	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
EIA51_07335	COG0596	Alpha beta hydrolase
EIA51_07345	COG0716	FMN binding
EIA51_07350	COG0735	belongs to the Fur family
EIA51_07360	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EIA51_07365	COG3094	Invasion gene expression up-regulator, SirB
EIA51_07380	COG4221	oxidoreductase activity
EIA51_07400	COG2814	Major facilitator Superfamily
EIA51_07415	COG2249	NAD(P)H dehydrogenase (quinone) activity
EIA51_07420	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EIA51_07425	COG0525	valine-tRNA ligase activity
EIA51_07440	COG4185	zeta toxin
EIA51_07445	COG2153	protein acetylation
EIA51_07450	COG2927	DNA polymerase III (CHI subunit)
EIA51_07460	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EIA51_07465	COG0512	Glutamine amidotransferase of anthranilate synthase
EIA51_07470	COG1942	4-Oxalocrotonate Tautomerase
EIA51_07475	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EIA51_07480	COG0134	indole-3-glycerol-phosphate synthase activity
EIA51_07480	COG0135	phosphoribosylanthranilate isomerase activity
EIA51_07495	COG3422	double-strand break repair
EIA51_07505	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EIA51_07505	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EIA51_07510	COG0516	GMP reductase activity
EIA51_07510	COG0517	IMP dehydrogenase activity
EIA51_07530	COG0519	Catalyzes the synthesis of GMP from XMP
EIA51_07530	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EIA51_07535	COG0582	viral genome integration into host DNA
EIA51_07570	COG3646	Phage regulatory protein
EIA51_07595	COG3179	chitinase
EIA51_07790	COG1484	DNA-dependent DNA replication
EIA51_07920	COG2974	May be involved in recombination
EIA51_07965	COG0270	DNA (cytosine-5-)-methyltransferase activity
EIA51_07985	COG0251	oxidation-reduction process
EIA51_07990	COG3021	interspecies interaction between organisms
EIA51_08000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EIA51_08055	COG1982	Orn Lys Arg decarboxylase major
EIA51_08060	COG0531	amino acid
EIA51_08070	COG2217	Heavy metal translocating P-type atpase
EIA51_08085	COG3383	formate dehydrogenase (NAD+) activity
EIA51_08085	COG0243	molybdopterin cofactor binding
EIA51_08090	COG3383	formate dehydrogenase (NAD+) activity
EIA51_08090	COG0243	molybdopterin cofactor binding
EIA51_08095	COG0437	4 iron, 4 sulfur cluster binding
EIA51_08100	COG2864	formate dehydrogenase
EIA51_08125	COG1687	branched-chain amino acid
EIA51_08130	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EIA51_08135	COG0583	DNA-binding transcription factor activity
EIA51_08145	COG0471	metal ion transport
EIA51_08160	COG1643	Atp-dependent helicase
EIA51_08165	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EIA51_08170	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EIA51_08180	COG0484	heat shock protein binding
EIA51_08185	COG0443	Heat shock 70 kDa protein
EIA51_08190	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EIA51_08200	COG0739	heme binding
EIA51_08205	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EIA51_08220	COG2850	peptidyl-arginine hydroxylation
EIA51_08230	COG2867	negative regulation of translational initiation
EIA51_08240	COG0012	GTP binding
EIA51_08250	COG0531	amino acid
EIA51_08255	COG3283	Transcriptional regulator of aromatic amino acids metabolism
EIA51_08265	COG3106	COG3106 Predicted ATPase
EIA51_08270	COG4166	transmembrane transport
EIA51_08275	COG4168	peptide transport system, permease
EIA51_08280	COG4171	peptide transport system, permease
EIA51_08285	COG4172	Belongs to the ABC transporter superfamily
EIA51_08290	COG4172	Belongs to the ABC transporter superfamily
EIA51_08295	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EIA51_08315	COG2259	Doxx family
EIA51_08330	COG0151	Belongs to the GarS family
EIA51_08335	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EIA51_08340	COG0745	RESPONSE REGULATOR receiver
EIA51_08360	COG0023	Translation Initiation Factor
EIA51_08370	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EIA51_08375	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
EIA51_08380	COG0776	regulation of translation
EIA51_08385	COG0539	negative regulation of cytoplasmic translation
EIA51_08395	COG4771	TonB-dependent receptor
EIA51_08400	COG0612	Peptidase, M16
EIA51_08405	COG2990	Protein conserved in bacteria
EIA51_08415	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EIA51_08450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EIA51_08455	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EIA51_08460	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EIA51_08465	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EIA51_08475	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EIA51_08480	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EIA51_08485	COG1454	alcohol dehydrogenase
EIA51_08485	COG1012	belongs to the aldehyde dehydrogenase family
EIA51_08500	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EIA51_08510	COG4178	(ABC) transporter
EIA51_08520	COG5413	integral membrane protein
EIA51_08525	COG4977	sequence-specific DNA binding
EIA51_08525	COG1917	Cupin 2, conserved barrel domain protein
EIA51_08530	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EIA51_08535	COG1115	amino acid carrier protein
EIA51_08545	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
EIA51_08545	COG0237	dephospho-CoA kinase activity
EIA51_08555	COG1459	type II secretion system
EIA51_08560	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EIA51_08560	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EIA51_08565	COG3715	PTS system
EIA51_08570	COG3716	PTS system mannose fructose sorbose family IID component
EIA51_08585	COG0328	RNA-DNA hybrid ribonuclease activity
EIA51_08615	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EIA51_08620	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EIA51_08625	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EIA51_08645	COG0495	leucyl-tRNA aminoacylation
EIA51_08650	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
EIA51_08655	COG1466	dna polymerase III delta subunit
EIA51_08665	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EIA51_08680	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EIA51_08685	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EIA51_08690	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
EIA51_08700	COG0750	zinc metalloprotease
EIA51_08705	COG0575	Belongs to the CDS family
EIA51_08725	COG0528	UMP kinase activity
EIA51_08730	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EIA51_08735	COG4969	Belongs to the N-Me-Phe pilin family
EIA51_08740	COG3023	N-Acetylmuramoyl-L-alanine amidase
EIA51_08750	COG0494	nUDIX hydrolase
EIA51_08755	COG0730	response to heat
EIA51_08765	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EIA51_08770	COG0590	tRNA wobble adenosine to inosine editing
EIA51_08775	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EIA51_08780	COG0363	glucosamine-6-phosphate deaminase activity
EIA51_08785	COG1793	dna ligase
EIA51_08825	COG1215	transferase activity, transferring glycosyl groups
EIA51_08855	COG0602	queuosine metabolic process
EIA51_08860	COG0720	synthase
EIA51_08865	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EIA51_08870	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EIA51_08890	COG0626	cystathionine gamma-synthase activity
EIA51_08895	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EIA51_08905	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EIA51_08910	COG0142	geranyltranstransferase activity
EIA51_08925	COG0697	spore germination
EIA51_08970	COG3210	domain, Protein
EIA51_08975	COG3210	domain, Protein
EIA51_08980	COG2831	hemolysin activation secretion protein
EIA51_08990	COG1846	Transcriptional regulator
EIA51_09005	COG1846	Transcriptional regulator
EIA51_09010	COG1566	PFAM secretion protein HlyD family protein
EIA51_09015	COG2814	Major facilitator Superfamily
EIA51_09025	COG0557	exoribonuclease II activity
EIA51_09045	COG0681	Belongs to the peptidase S26 family
EIA51_09060	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EIA51_09085	COG0105	UTP biosynthetic process
EIA51_09105	COG0784	Response regulator, receiver
EIA51_09105	COG2198	Histidine kinase
EIA51_09105	COG5002	protein histidine kinase activity
EIA51_09110	COG0385	Bile acid
EIA51_09115	COG2814	Major facilitator Superfamily
EIA51_09120	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EIA51_09125	COG2252	PERMEase
EIA51_09130	COG1555	photosystem II stabilization
EIA51_09135	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EIA51_09140	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EIA51_09150	COG1238	metal cluster binding
EIA51_09155	COG0110	maltose O-acetyltransferase activity
EIA51_09160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EIA51_09185	COG1238	metal cluster binding
EIA51_09205	COG4783	chaperone-mediated protein folding
EIA51_09215	COG0814	amino acid
EIA51_09220	COG2226	methyltransferase
EIA51_09225	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EIA51_09230	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EIA51_09245	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EIA51_09245	COG0131	Imidazoleglycerol-phosphate dehydratase
EIA51_09250	COG4804	nuclease activity
EIA51_09260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EIA51_09270	COG0107	imidazoleglycerol-phosphate synthase activity
EIA51_09285	COG3161	chorismate lyase activity
EIA51_09290	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EIA51_09295	COG2233	PERMEase
EIA51_09300	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EIA51_09305	COG0066	3-isopropylmalate dehydratase activity
EIA51_09325	COG4133	protoheme IX ABC transporter activity
EIA51_09330	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EIA51_09335	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EIA51_09340	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EIA51_09350	COG1138	Cytochrome C-type biogenesis protein
EIA51_09355	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EIA51_09370	COG4211	Belongs to the binding-protein-dependent transport system permease family
EIA51_09375	COG1129	ABC transporter
EIA51_09380	COG1879	ABC-type sugar transport system periplasmic component
EIA51_09385	COG1085	galactose-1-phosphate uridylyltransferase
EIA51_09395	COG2017	converts alpha-aldose to the beta-anomer
EIA51_09405	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EIA51_09410	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EIA51_09415	COG1882	Formate acetyltransferase
EIA51_09420	COG2116	formate transmembrane transporter activity
EIA51_09425	COG0537	adenosine 5'-monophosphoramidase activity
EIA51_09440	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EIA51_09455	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EIA51_09460	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EIA51_09465	COG0254	rRNA binding
EIA51_09470	COG1253	flavin adenine dinucleotide binding
EIA51_09480	COG0084	hydrolase, TatD family'
EIA51_09485	COG0470	DNA polymerase III
EIA51_09490	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EIA51_09495	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EIA51_09505	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EIA51_09520	COG0330	HflC and HflK could
EIA51_09525	COG0330	HflC and HflK could
EIA51_09540	COG0326	Molecular chaperone. Has ATPase activity
EIA51_09545	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EIA51_09550	COG3091	SprT-like family
EIA51_09555	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EIA51_09560	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EIA51_09600	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EIA51_09620	COG0210	DNA helicase
EIA51_09625	COG5645	(Lipo)protein
EIA51_09640	COG1447	Phosphotransferase system cellobiose-specific component IIA
EIA51_09645	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EIA51_09650	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EIA51_09655	COG1446	asparaginase
EIA51_09660	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EIA51_09670	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EIA51_09675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EIA51_09700	COG2183	response to ionizing radiation
EIA51_09705	COG1114	Component of the transport system for branched-chain amino acids
EIA51_09730	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
EIA51_09735	COG0456	acetyltransferase
EIA51_09740	COG1022	Amp-dependent synthetase and ligase
EIA51_09745	COG1027	Aspartate ammonia-lyase
EIA51_09755	COG0740	serine-type endopeptidase activity
EIA51_09760	COG0544	peptidyl-prolyl cis-trans isomerase activity
EIA51_09780	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EIA51_09785	COG3263	regulation of cellular component size
EIA51_09790	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EIA51_09790	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EIA51_09800	COG3722	fumarate hydratase activity
EIA51_09805	COG0246	Mannitol dehydrogenase
EIA51_09820	COG0848	biopolymer transport protein
EIA51_09825	COG0811	peptide transport
EIA51_09830	COG4536	flavin adenine dinucleotide binding
EIA51_09835	COG4137	Cytochrome C assembly protein
EIA51_09840	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EIA51_09850	COG3036	rescue of stalled ribosome
EIA51_09855	COG1393	Belongs to the ArsC family
EIA51_09865	COG1126	abc transporter atp-binding protein
EIA51_09870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EIA51_09875	COG4215	(ABC) transporter
EIA51_09880	COG4160	amino acid transport
EIA51_09905	COG0174	glutamine synthetase
EIA51_09925	COG3306	glycosyltransferase involved in LPS biosynthesis
EIA51_09930	COG1216	Glycosyl transferase, family 2
EIA51_09945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EIA51_09960	COG3028	Belongs to the UPF0307 family
EIA51_09965	COG0312	modulator of DNA gyrase
EIA51_09970	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EIA51_09980	COG1271	oxidase subunit
EIA51_09985	COG1294	oxidase, subunit
EIA51_09995	COG3790	cyd operon protein YbgE
EIA51_10000	COG0824	Thioesterase
EIA51_10005	COG0811	peptide transport
EIA51_10010	COG0848	biopolymer transport protein
EIA51_10015	COG3064	Membrane
EIA51_10045	COG2165	general secretion pathway protein
EIA51_10050	COG4795	General secretion pathway protein
EIA51_10065	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EIA51_10070	COG0561	phosphatase activity
EIA51_10075	COG0235	Class ii aldolase
EIA51_10080	COG3623	hexulose-6-phosphate isomerase
EIA51_10105	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
EIA51_10175	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
EIA51_10180	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EIA51_10185	COG1739	Uncharacterized protein family UPF0029
EIA51_10190	COG0425	Belongs to the sulfur carrier protein TusA family
EIA51_10200	COG4942	peptidase
EIA51_10205	COG2861	carbohydrate metabolic process
EIA51_10210	COG1040	competence protein
EIA51_10220	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EIA51_10235	COG3850	Histidine kinase
EIA51_10240	COG3062	negative regulation of establishment of protein localization
EIA51_10245	COG0243	molybdopterin cofactor binding
EIA51_10250	COG0437	4 iron, 4 sulfur cluster binding
EIA51_10255	COG0348	domain, Protein
EIA51_10260	COG3043	anaerobic respiration
EIA51_10265	COG3005	denitrification pathway
EIA51_10275	COG4785	May be involved in cell division
EIA51_10280	COG0513	Belongs to the DEAD box helicase family
EIA51_10295	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
EIA51_10300	COG0569	domain protein
EIA51_10305	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EIA51_10305	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EIA51_10320	COG1252	NADH dehydrogenase
EIA51_10325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EIA51_10335	COG0191	fructose-bisphosphate aldolase activity
EIA51_10340	COG0126	phosphoglycerate kinase activity
EIA51_10345	COG3719	Belongs to the RNase T2 family
EIA51_10350	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EIA51_10355	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EIA51_10360	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EIA51_10370	COG0778	Nitroreductase
EIA51_10375	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EIA51_10380	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EIA51_10385	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EIA51_10395	COG1045	serine acetyltransferase
EIA51_10400	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EIA51_10405	COG2194	sulfuric ester hydrolase activity
EIA51_10410	COG0789	Transcriptional regulator
EIA51_10415	COG2814	Major facilitator Superfamily
EIA51_10420	COG1187	pseudouridine synthase activity
EIA51_10425	COG0280	phosphate acetyltransferase
EIA51_10425	COG0281	malic enzyme
EIA51_10435	COG1368	sulfuric ester hydrolase activity
EIA51_10440	COG0335	large ribosomal subunit rRNA binding
EIA51_10450	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EIA51_10455	COG0228	four-way junction DNA binding
EIA51_10460	COG0859	PFAM glycosyl transferase family 9
EIA51_10465	COG0463	Glycosyl transferase, family 2
EIA51_10470	COG0561	phosphatase activity
EIA51_10475	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EIA51_10475	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EIA51_10480	COG3715	PTS system
EIA51_10485	COG3716	PTS system mannose fructose sorbose family IID component
EIA51_10500	COG3676	manually curated
EIA51_10520	COG0633	Ferredoxin
EIA51_10530	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EIA51_10540	COG0822	iron-sulfur transferase activity
EIA51_10550	COG1959	2 iron, 2 sulfur cluster binding
EIA51_10555	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
EIA51_10570	COG2837	iron assimilation
EIA51_10580	COG0513	Belongs to the DEAD box helicase family
EIA51_10585	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EIA51_10620	COG0004	ammonium transporteR
EIA51_10625	COG2990	Protein conserved in bacteria
EIA51_10630	COG0433	COG0433 Predicted ATPase
EIA51_10665	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EIA51_10670	COG0668	transmembrane transport
EIA51_10675	COG0248	Ppx GppA phosphatase
EIA51_10680	COG2911	Protein conserved in bacteria
EIA51_10690	COG0728	peptidoglycan biosynthetic process
EIA51_10700	COG0268	Binds directly to 16S ribosomal RNA
EIA51_10710	COG0560	Phosphoserine phosphatase
EIA51_10730	COG3085	chromosome segregation
EIA51_10735	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EIA51_10740	COG3084	Protein conserved in bacteria
EIA51_10750	COG0354	folic acid binding
EIA51_10755	COG1561	YicC-like family, N-terminal region
EIA51_10760	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EIA51_10765	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EIA51_10770	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EIA51_10780	COG0402	S-adenosylhomocysteine deaminase activity
EIA51_10785	COG3083	sulfuric ester hydrolase activity
EIA51_10800	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EIA51_10805	COG0745	RESPONSE REGULATOR receiver
EIA51_10810	COG1584	GPR1 FUN34 yaaH family protein
EIA51_10815	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EIA51_10820	COG0085	RNA polymerase activity
EIA51_10835	COG0081	regulation of translation
EIA51_10840	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EIA51_10865	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EIA51_10870	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EIA51_10880	COG0049	tRNA binding
EIA51_10900	COG2923	Belongs to the DsrF TusC family
EIA51_10910	COG2964	Protein conserved in bacteria
EIA51_10915	COG0545	Peptidyl-prolyl cis-trans isomerase
EIA51_10925	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EIA51_10925	COG0678	peroxiredoxin activity
EIA51_10930	COG0583	DNA-binding transcription factor activity
EIA51_10935	COG1309	transcriptional regulator
EIA51_10940	COG2267	carboxylic ester hydrolase activity
EIA51_10945	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EIA51_10950	COG0561	phosphatase activity
EIA51_10960	COG3978	acetolactate synthase activity
EIA51_11000	COG1522	sequence-specific DNA binding
EIA51_11010	COG3021	interspecies interaction between organisms
EIA51_11020	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EIA51_11025	COG2818	Glycosylase
EIA51_11030	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EIA51_11035	COG3477	response to acidic pH
EIA51_11050	COG0538	isocitrate dehydrogenase activity
EIA51_11070	COG4145	pantothenate transmembrane transporter activity
EIA51_11075	COG3924	membrane
EIA51_11080	COG0439	Biotin carboxylase
EIA51_11085	COG0511	ligase activity, forming carbon-carbon bonds
EIA51_11090	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EIA51_11105	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EIA51_11115	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EIA51_11125	COG1530	ribonuclease E activity
EIA51_11135	COG3276	selenocysteine insertion sequence binding
EIA51_11140	COG1921	L-seryl-tRNASec selenium transferase activity
EIA51_11145	COG3171	Protein conserved in bacteria
EIA51_11150	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EIA51_11155	COG0606	chelatase, subunit chli
EIA51_11160	COG0076	glutamate decarboxylase activity
EIA51_11165	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EIA51_11170	COG3787	Belongs to the UPF0306 family
EIA51_11175	COG3071	HemY protein
EIA51_11180	COG2959	enzyme of heme biosynthesis
EIA51_11190	COG0181	hydroxymethylbilane synthase activity
EIA51_11200	COG2197	response regulator
EIA51_11210	COG1295	ribonuclease BN
EIA51_11220	COG1414	Transcriptional regulator
EIA51_11230	COG2731	YhcH YjgK YiaL family protein
EIA51_11235	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EIA51_11240	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EIA51_11245	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EIA51_11255	COG3623	hexulose-6-phosphate isomerase
EIA51_11260	COG0235	Class ii aldolase
EIA51_11270	COG2884	Cell division ATP-binding protein ftsE
EIA51_11275	COG2177	Part of the ABC transporter FtsEX involved in
EIA51_11285	COG0762	integral membrane protein
EIA51_11290	COG0598	Magnesium transport protein CorA
EIA51_11300	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EIA51_11345	COG4453	Protein conserved in bacteria
EIA51_11605	COG0640	Transcriptional regulator
EIA51_11620	COG0786	glutamate:sodium symporter activity