locus-tag	class	description
CEW87_00010	ENOG4107STF	Involved in phosphonate degradation (By similarity)
CEW87_00030	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
CEW87_00035	ENOG4107QR9	Iron-sulfur cluster binding protein
CEW87_00040	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
CEW87_00050	ENOG4108NIW	Leucine export protein LeuE
CEW87_00055	ENOG4108NDG	TRAP dicarboxylate
CEW87_00060	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CEW87_00080	ENOG4105DZG	Dehydrogenase
CEW87_00095	ENOG4105BZU	Histidine kinase
CEW87_00100	ENOG4105WH1	Two component transcriptional regulator luxr family
CEW87_00105	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CEW87_00115	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
CEW87_00120	ENOG4105CYM	Glutathione S-transferase
CEW87_00125	ENOG4105CBC	glutamate synthase
CEW87_00130	ENOG4105C0A	alcohol dehydrogenase
CEW87_00145	ENOG4105E9K	Isocitrate dehydrogenase
CEW87_00150	ENOG4105CHB	tonB-dependent Receptor
CEW87_00175	ENOG4105C26	Dehydrogenase
CEW87_00180	ENOG4107R7Y	intracellular protease Pfpi family
CEW87_00190	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
CEW87_00200	ENOG4105E39	Enoyl-CoA hydratase
CEW87_00210	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
CEW87_00215	ENOG4108IV0	ABC, transporter
CEW87_00220	ENOG4105C0Z	ABC transporter
CEW87_00240	ENOG4105CEY	Amp-dependent synthetase and ligase
CEW87_00245	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
CEW87_00250	ENOG4105CHU	acetyl-coa acetyltransferase
CEW87_00260	ENOG41060WC	Enoyl-CoA hydratase
CEW87_00265	ENOG4105CC9	acyl-Coa dehydrogenase
CEW87_00270	ENOG4105C1G	acyl-Coa dehydrogenase
CEW87_00275	ENOG4105CHC	glucokinase (EC 2.7.1.2)
CEW87_00280	ENOG4107QP8	phosphohexose isomerase
CEW87_00285	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
CEW87_00295	ENOG4105EAH	synthase
CEW87_00300	ENOG4107T6V	glycerophosphoryl diester phosphodiesterase
CEW87_00315	ENOG4105CPC	Aldo Keto reductase
CEW87_00320	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
CEW87_00325	ENOG4105C1J	atp-dependent rna helicase
CEW87_00330	ENOG4105BZU	Histidine kinase
CEW87_00340	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
CEW87_00345	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
CEW87_00350	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CEW87_00355	ENOG4105CD8	aminopeptidase N
CEW87_00385	ENOG4107QN1	sodium solute
CEW87_00395	ENOG4107YZX	Universal stress protein
CEW87_00400	ENOG4108HMX	isocitrate dehydrogenase (NADP)
CEW87_00405	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
CEW87_00415	ENOG4108XRS	Monoheme cytochrome SoxX (Sulfur oxidation)
CEW87_00435	ENOG4105W2Z	cytochrome C, class I
CEW87_00440	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
CEW87_00445	ENOG4107YCR	Transcriptional regulator, ARSR family
CEW87_00455	ENOG4107S7U	Sulfide dehydrogenase
CEW87_00470	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
CEW87_00475	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
CEW87_00480	ENOG4105W5Q	DNA repair protein (RadC
CEW87_00485	ENOG4105KDC	50s ribosomal protein l28
CEW87_00490	ENOG4105W0E	50S ribosomal protein L33
CEW87_00495	ENOG4105VEQ	Cold shock protein
CEW87_00500	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
CEW87_00505	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CEW87_00510	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
CEW87_00515	ENOG4108I9X	Isocitrate lyase
CEW87_00525	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CEW87_00530	ENOG4105E0F	Histidine kinase
CEW87_00535	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
CEW87_00540	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
CEW87_00560	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
CEW87_00565	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
CEW87_00570	ENOG4105DR5	peptidase
CEW87_00575	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
CEW87_00580	ENOG4108UJD	30S ribosomal protein S9
CEW87_00585	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
CEW87_00595	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
CEW87_00605	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
CEW87_00610	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
CEW87_00615	ENOG4105E4C	Lytic transglycosylase catalytic
CEW87_00630	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
CEW87_00645	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
CEW87_00650	ENOG4107DKM	chad domain containing protein
CEW87_00670	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
CEW87_00685	ENOG4105CM2	brancheD-chain amino acid aminotransferase
CEW87_00700	ENOG4105DNZ	Alpha Beta Hydrolase
CEW87_00710	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
CEW87_00715	ENOG4108WBT	adenosyltransferase
CEW87_00720	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
CEW87_00730	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
CEW87_00735	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
CEW87_00740	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
CEW87_00745	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
CEW87_00750	ENOG4105N42	UPF0307 protein
CEW87_00755	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
CEW87_00760	ENOG4105BZU	Histidine kinase
CEW87_00765	ENOG4105CVE	Lytic murein transglycosylase
CEW87_00780	ENOG41067MG	lrgb family
CEW87_00790	ENOG4105BZU	Histidine kinase
CEW87_00795	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CEW87_00815	ENOG4105BZS	acriflavin resistance protein
CEW87_00825	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
CEW87_00830	ENOG4105C02	permease
CEW87_00835	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
CEW87_00845	ENOG4108X4D	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
CEW87_00855	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
CEW87_00870	ENOG4105E98	transcriptional regulator DeoR family
CEW87_00875	ENOG4105DJ0	Poly(A) Polymerase
CEW87_00880	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CEW87_00895	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
CEW87_00900	ENOG4105W8H	transhydrogenase (subunit alpha
CEW87_00905	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
CEW87_00915	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
CEW87_00920	ENOG4105EU8	FAD linked oxidase domain protein
CEW87_00925	ENOG4105CQB	FAD linked oxidase domain protein
CEW87_00930	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
CEW87_00940	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
CEW87_00945	ENOG4105K46	50S ribosomal protein l27
CEW87_00950	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CEW87_00955	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
CEW87_00985	ENOG4105D60	lipoprotein releasing system transmembrane protein
CEW87_01000	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
CEW87_01020	ENOG4108V0P	LemA family
CEW87_01030	ENOG4105C5H	ABC transporter
CEW87_01050	ENOG4105E4C	Lytic transglycosylase catalytic
CEW87_01070	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CEW87_01085	ENOG4108Z7G	MaoC domain protein dehydratase
CEW87_01095	ENOG4105FZE	dinitrogenase iron-molybdenum cofactor biosynthesis
CEW87_01100	ENOG4107IVC	4Fe-4S ferredoxin, iron-sulfur binding
CEW87_01110	ENOG4105CY9	nitrogenase molybdenum-iron protein beta chain
CEW87_01115	ENOG4105D0B	Nitrogenase protein alpha chain
CEW87_01120	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
CEW87_01125	ENOG4108K8Z	nad( )--dinitrogen-reductase ADP-d-ribosyltransferase
CEW87_01140	ENOG41065RQ	ADP-ribosylation crystallin J1
CEW87_01145	ENOG4105PS4	nifq family
CEW87_01150	ENOG4105U82	Ferredoxin
CEW87_01155	ENOG4105KXW	Ferredoxin
CEW87_01160	ENOG4105CNW	domain protein
CEW87_01170	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
CEW87_01175	ENOG4105CGC	Nitrogenase cofactor biosynthesis protein NifB
CEW87_01180	ENOG4105CA0	peroxidase
CEW87_01185	ENOG4108JUA	Transcriptional regulator
CEW87_01190	ENOG4105DS4	PAS PAC sensor Signal transduction histidine kinase
CEW87_01195	ENOG4105DGN	Electron transport complex
CEW87_01200	ENOG4108R3D	Electron transport complex
CEW87_01205	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
CEW87_01210	ENOG4105D6A	Electron transport complex
CEW87_01215	ENOG4108UQQ	Electron transport complex
CEW87_01220	ENOG4108E8M	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
CEW87_01225	ENOG4105VDB	UPF0125 protein
CEW87_01230	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CEW87_01255	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CEW87_01265	ENOG4108JU6	CBS domain protein
CEW87_01270	ENOG4107QHF	type ii secretion system protein e
CEW87_01295	ENOG4105C9M	aspartyl-trna synthetase
CEW87_01310	ENOG4105C8J	)-transporter
CEW87_01315	ENOG4108YXU	transcriptional regulator AsnC family
CEW87_01320	ENOG4108V1T	peptidylprolyl cis-trans isomerase
CEW87_01325	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
CEW87_01335	ENOG4105DK0	Indole-3-glycerol phosphate synthase
CEW87_01340	ENOG4107QYG	anthranilate phosphoribosyltransferase
CEW87_01345	ENOG4105DDQ	anthranilate synthase
CEW87_01360	ENOG4107QJE	Chromosome Partitioning Protein
CEW87_01395	ENOG4107YH6	single-stranded DNA-binding protein
CEW87_01400	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
CEW87_01580	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
CEW87_01590	ENOG4105VT3	DNA binding domain protein, excisionase family
CEW87_01645	ENOG4105W5Q	DNA repair protein (RadC
CEW87_01725	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
CEW87_01730	ENOG4105D0S	secretion protein (HlyD
CEW87_01735	ENOG4105CJ1	ABC, transporter
CEW87_01740	ENOG4105CMI	transporter
CEW87_01750	ENOG4105CHR	reductase
CEW87_01765	ENOG4105CHR	reductase
CEW87_01770	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
CEW87_01775	ENOG4105D6U	Sodium Glutamate Symporter
CEW87_01780	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
CEW87_01785	ENOG41081QV	Universal stress protein
CEW87_01795	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
CEW87_01805	ENOG4105CY0	Metallo-Beta-Lactamase
CEW87_01810	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
CEW87_01815	ENOG4106NZI	LysR family Transcriptional regulator
CEW87_01830	ENOG4105DFP	Integrase
CEW87_01840	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
CEW87_01845	ENOG4105DJV	ribulose-phosphate 3-epimerase
CEW87_01850	ENOG4107QHF	type ii secretion system protein e
CEW87_01855	ENOG4107RF4	Phosphodiesterase
CEW87_01870	ENOG4105EKQ	RNA-directed DNA polymerase
CEW87_01875	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
CEW87_01880	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
CEW87_01895	ENOG4107QNR	UPF0135 protein
CEW87_01900	ENOG4105C0H	protease
CEW87_01905	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
CEW87_01910	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
CEW87_01915	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
CEW87_01920	ENOG4105K59	histidine triad (HIT) protein
CEW87_01925	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
CEW87_01930	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
CEW87_01935	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
CEW87_01940	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
CEW87_01945	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
CEW87_01950	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
CEW87_01955	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CEW87_01960	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
CEW87_01965	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
CEW87_01970	ENOG4105NXH	GreA GreB family elongation factor
CEW87_01975	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
CEW87_01985	ENOG4105E3A	(ABC) transporter
CEW87_01990	ENOG4105DA5	(ABC) transporter
CEW87_02010	ENOG4107PE3	Mammalian cell entry related domain protein
CEW87_02015	ENOG4105CY3	ABC transporter, permease
CEW87_02020	ENOG4105DHJ	ABC, transporter
CEW87_02030	ENOG4107QHF	type ii secretion system protein e
CEW87_02075	ENOG4105C2X	Arabinose 5-phosphate isomerase
CEW87_02085	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
CEW87_02090	ENOG4105E39	Enoyl-CoA hydratase
CEW87_02105	ENOG4105E9Q	Acyl-transferase
CEW87_02110	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
CEW87_02115	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
CEW87_02120	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
CEW87_02125	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
CEW87_02130	ENOG4108JU5	Magnesium and cobalt efflux protein
CEW87_02135	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
CEW87_02140	ENOG4105C9A	Phoh family
CEW87_02145	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
CEW87_02160	ENOG4105BZU	Histidine kinase
CEW87_02165	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
CEW87_02170	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
CEW87_02175	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
CEW87_02180	ENOG4105DND	Transcriptional regulator
CEW87_02200	ENOG4105BZU	Histidine kinase
CEW87_02205	ENOG4107QX3	carboxylase
CEW87_02215	ENOG4105PV1	biotin lipoyl attachment domaiN-containing protein
CEW87_02220	ENOG4105D9Q	decarboxylase (Beta subunit)
CEW87_02230	ENOG4108JU3	Alkyl hydroperoxide reductase
CEW87_02245	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
CEW87_02250	ENOG4105CAK	Cell division ATP-binding protein ftsE
CEW87_02265	ENOG4105C1V	Peptidase, M16
CEW87_02270	ENOG4106H78	methyltransferase
CEW87_02275	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
CEW87_02280	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
CEW87_02285	ENOG410890F	Dynamin family
CEW87_02290	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
CEW87_02300	ENOG41081V9	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
CEW87_02305	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
CEW87_02315	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
CEW87_02320	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
CEW87_02325	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
CEW87_02330	ENOG4105C3G	gtp-binding protein
CEW87_02335	ENOG4105EVH	UPF0753 protein
CEW87_02340	ENOG4105D65	subunit l
CEW87_02345	ENOG4105DUM	transcriptional regulator, lysR family
CEW87_02355	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
CEW87_02370	ENOG4105E33	succinate dehydrogenase
CEW87_02385	ENOG4108UYB	regulatoR
CEW87_02390	ENOG4105TX3	Histidine kinase
CEW87_02400	ENOG4105HEE	Binding Domain protein
CEW87_02410	ENOG4105DH4	Periplasmic copper-binding protein
CEW87_02415	ENOG4105CIG	ABC transporter
CEW87_02420	ENOG4108T0W	nitrous oxide maturation protein NosY
CEW87_02445	ENOG4105MPD	Cytochrome
CEW87_02465	ENOG4105C5H	ABC transporter
CEW87_02470	ENOG4105SKE	transcriptional Regulator LysR family
CEW87_02475	ENOG4105CBP	Major Facilitator
CEW87_02490	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
CEW87_02500	ENOG4105BZU	Histidine kinase
CEW87_02535	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
CEW87_02590	ENOG4105E2V	Glycosyltransferase 36
CEW87_02605	ENOG4108UXE	Protein tyrosine phosphatase
CEW87_02610	ENOG4105D6J	arsenicaL-resistance protein
CEW87_02625	ENOG4105EQ1	Transcriptional regulator
CEW87_02650	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
CEW87_02655	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CEW87_02660	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
CEW87_02665	ENOG4105F38	ABC transporter, permease
CEW87_02675	ENOG4105E98	transcriptional regulator DeoR family
CEW87_02690	ENOG4105ETT	transcriptional Regulator, LysR family
CEW87_02700	ENOG4105BZU	Histidine kinase
CEW87_02750	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CEW87_02755	ENOG4107TUY	Histidine kinase
CEW87_02765	ENOG4105CHM	Aminotransferase
CEW87_02770	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
CEW87_02775	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
CEW87_02780	ENOG4105BZU	Histidine kinase
CEW87_02785	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
CEW87_02790	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
CEW87_02795	ENOG4108MTB	glycosyl transferase family
CEW87_02800	ENOG4105EUB	pirin domain protein
CEW87_02805	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
CEW87_02810	ENOG4105JQN	Transcriptional regulator
CEW87_02815	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
CEW87_02830	ENOG4105BZS	acriflavin resistance protein
CEW87_02845	ENOG4105CUZ	uba thif-type nad fad binding protein
CEW87_02855	ENOG4105C87	Aminotransferase class I and II
CEW87_02860	ENOG4105BZU	Histidine kinase
CEW87_02870	ENOG4105BZU	Histidine kinase
CEW87_02885	ENOG4107RDB	Major Facilitator
CEW87_02900	ENOG4105CMR	udp-glucose 4-epimerase
CEW87_02905	ENOG4108ZT0	50S ribosomal protein l17
CEW87_02910	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CEW87_02915	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
CEW87_02920	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
CEW87_02925	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CEW87_02930	ENOG41067V7	50S ribosomal protein L36
CEW87_02935	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
CEW87_02940	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
CEW87_02945	ENOG4105VPB	50S ribosomal protein L30
CEW87_02950	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
CEW87_02955	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
CEW87_02960	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
CEW87_02965	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
CEW87_02970	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
CEW87_02975	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CEW87_02980	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
CEW87_02985	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
CEW87_02990	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
CEW87_02995	ENOG41084PQ	50s ribosomal protein l29
CEW87_03000	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
CEW87_03005	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
CEW87_03010	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
CEW87_03015	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
CEW87_03020	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CEW87_03025	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
CEW87_03030	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
CEW87_03035	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
CEW87_03040	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
CEW87_03045	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CEW87_03050	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
CEW87_03055	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
CEW87_03060	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
CEW87_03065	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CEW87_03070	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CEW87_03075	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
CEW87_03080	ENOG4108VZM	50s ribosomal protein L10
CEW87_03085	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
CEW87_03090	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
CEW87_03095	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
CEW87_03100	ENOG4105PM1	preprotein translocase subunit SecE
CEW87_03110	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CEW87_03135	ENOG4108JJ7	ABC transporter
CEW87_03150	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
CEW87_03155	ENOG4107RP9	extracellular solute-binding protein, family 3
CEW87_03160	ENOG4107RB3	L-asparaginase
CEW87_03165	ENOG4107R11	Transcriptional regulator
CEW87_03170	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
CEW87_03185	ENOG4105C11	sulfate adenylyltransferase), subunit 2
CEW87_03190	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
CEW87_03195	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
CEW87_03200	ENOG4105EFT	decarboxylase
CEW87_03205	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
CEW87_03215	ENOG4105D0M	Protease HtpX homolog
CEW87_03220	ENOG4105C1J	atp-dependent rna helicase
CEW87_03225	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
CEW87_03235	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
CEW87_03240	ENOG4105DAT	cobalamin (vitamin b12) biosynthesis cbix protein
CEW87_03245	ENOG41081F0	Precorrin-8x methylmutase
CEW87_03250	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
CEW87_03255	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
CEW87_03260	ENOG4105DVK	Precorrin-2 c20-methyltransferase
CEW87_03265	ENOG4108P62	biosynthesis protein (CbiG)
CEW87_03275	ENOG4105E4R	Precorrin-3B C17-methyltransferase
CEW87_03285	ENOG4105CYC	Transferase
CEW87_03335	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
CEW87_03340	ENOG41082J7	Rhodanese domain protein
CEW87_03345	ENOG4105DFG	type I secretion outer membrane protein
CEW87_03350	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CEW87_03355	ENOG4105E0F	Histidine kinase
CEW87_03370	ENOG4108R3E	Dna-3-methyladenine glycosylase i
CEW87_03380	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
CEW87_03385	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
CEW87_03390	ENOG4105EA8	2-Nitropropane dioxygenase
CEW87_03395	ENOG4105BZU	Histidine kinase
CEW87_03420	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CEW87_03435	ENOG4105BZU	Histidine kinase
CEW87_03440	ENOG4108ZHJ	Organic hydroperoxide resistance protein
CEW87_03450	ENOG4105JSC	dimethylmenaquinone methyltransferase
CEW87_03480	ENOG4107YCY	Transcriptional regulator
CEW87_03485	ENOG4105FG0	Nitroreductase
CEW87_03495	ENOG4105CC0	LysR family Transcriptional regulator
CEW87_03510	ENOG4105BZU	Histidine kinase
CEW87_03520	ENOG4105BZU	Histidine kinase
CEW87_03555	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
CEW87_03565	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
CEW87_03585	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
CEW87_03590	ENOG4105D49	3-dehydroquinate synthase
CEW87_03595	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
CEW87_03600	ENOG4105E4G	Type IV pilus
CEW87_03625	ENOG4108JQC	penicillin-binding protein 1A
CEW87_03630	ENOG4105XQ6	frataxin-like protein
CEW87_03640	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
CEW87_03660	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
CEW87_03665	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
CEW87_03670	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
CEW87_03675	ENOG4105CB5	ATP-dependent DNA helicase recG
CEW87_03680	ENOG4105KME	endoribonuclease L-psp
CEW87_03685	ENOG41085EG	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
CEW87_03715	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CEW87_03725	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CEW87_03730	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CEW87_03735	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CEW87_03740	ENOG4105CHU	acetyl-coa acetyltransferase
CEW87_03750	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
CEW87_03760	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
CEW87_03765	ENOG4105CHU	acetyl-coa acetyltransferase
CEW87_03770	ENOG4107QPN	acyl-Coa dehydrogenase
CEW87_03795	ENOG4105CKI	cobalamin synthesis protein
CEW87_03800	ENOG4105CQB	FAD linked oxidase domain protein
CEW87_03820	ENOG4105WH1	Two component transcriptional regulator luxr family
CEW87_03825	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
CEW87_03835	ENOG4105BZU	Histidine kinase
CEW87_03855	ENOG4108IV0	ABC, transporter
CEW87_03870	ENOG4105C32	Amino acid ABC transporter (Permease)
CEW87_03875	ENOG4105C0Z	ABC transporter
CEW87_03880	ENOG4108IQE	Amp-dependent synthetase and ligase
CEW87_03985	ENOG4105CF2	Mu-like prophage FluMu protein GP28
CEW87_04090	ENOG4105IKI	host-nuclease inhibitor protein
CEW87_04120	ENOG4105D5P	Methylmalonyl-coA mutase
CEW87_04135	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CEW87_04145	ENOG4105CGZ	zinc metallopeptidase
CEW87_04150	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
CEW87_04155	ENOG4105BZU	Histidine kinase
CEW87_04160	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
CEW87_04165	ENOG4107QX3	carboxylase
CEW87_04170	ENOG4105DJT	lAO AO transport system ATPase
CEW87_04175	ENOG4105D5P	Methylmalonyl-coA mutase
CEW87_04180	ENOG4105DRR	Transcriptional regulator, GntR family
CEW87_04185	ENOG4105C37	(CBS) domain
CEW87_04190	ENOG4105C9Q	fumarate hydratase class II
CEW87_04195	ENOG4107QN1	sodium solute
CEW87_04200	ENOG41062QD	Membrane
CEW87_04205	ENOG4105E39	Enoyl-CoA hydratase
CEW87_04210	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
CEW87_04215	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CEW87_04220	ENOG4108ZX6	Electron transport protein SCO1 SenC
CEW87_04225	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
CEW87_04250	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
CEW87_04260	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
CEW87_04265	ENOG4105BZ9	Cytochrome C oxidase, subunit I
CEW87_04270	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
CEW87_04280	ENOG4107GJV	short-chain dehydrogenase reductase
CEW87_04300	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
CEW87_04315	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
CEW87_04345	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
CEW87_04350	ENOG4105K4P	CoA-binding domain protein
CEW87_04375	ENOG4105DZQ	phospholipase D Transphosphatidylase
CEW87_04380	ENOG4105X23	Endonuclease Exonuclease phosphatase
CEW87_04385	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
CEW87_04400	ENOG4105C5F	glutamine synthetase
CEW87_04410	ENOG4105CUX	Signal transduction histidine kinase
CEW87_04415	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CEW87_04420	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
CEW87_04425	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
CEW87_04435	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
CEW87_04440	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
CEW87_04445	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
CEW87_04450	ENOG4105M6F	mutator MutT protein
CEW87_04460	ENOG4105CA3	membrane-bound lytic murein transglycosylase
CEW87_04465	ENOG4105T95	Thiol disulfide interChange protein
CEW87_04470	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
CEW87_04500	ENOG4105CDU	Replicative dna helicase
CEW87_04505	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
CEW87_04510	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
CEW87_04520	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
CEW87_04530	ENOG4105CQ7	ATP-dependent helicase
CEW87_04545	ENOG4105KRS	Proteinase inhibitor
CEW87_04550	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
CEW87_04555	ENOG4105IPS	esterase
CEW87_04560	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CEW87_04565	ENOG4105FR1	rard protein
CEW87_04580	ENOG4105E2X	shikimate dehydrogenase
CEW87_04585	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
CEW87_04590	ENOG4105CJW	magnesium transporter
CEW87_04600	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
CEW87_04605	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
CEW87_04615	ENOG4105VCQ	rubredoxin
CEW87_04620	ENOG4108UNF	response regulator
CEW87_04625	ENOG4105M3Z	response regulator
CEW87_04635	ENOG4105C8Q	Methyl-accepting chemotaxis
CEW87_04640	ENOG4105CBS	Chea signal transduction histidine kinase
CEW87_04645	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
CEW87_04650	ENOG4108UJU	UPF0301 protein
CEW87_04655	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
CEW87_04660	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
CEW87_04665	ENOG4105CXT	aspartate transcarbamylase
CEW87_04670	ENOG4105CD3	dihydroorotase
CEW87_04675	ENOG4105VZ9	UPF0235 protein
CEW87_04680	ENOG4108VIA	integral membrane protein
CEW87_04685	ENOG4105II7	pyrroline-5-carboxylate reductase
CEW87_04690	ENOG4105DFA	alanine racemase domain protein
CEW87_04695	ENOG4105CZX	twitching motility protein
CEW87_04700	ENOG4105CZX	twitching motility protein
CEW87_04705	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
CEW87_04725	ENOG4105QAX	Iron-sulfur
CEW87_04730	ENOG4108JB9	formate dehydrogenase
CEW87_04770	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
CEW87_04780	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
CEW87_04785	ENOG4105BZU	Histidine kinase
CEW87_04795	ENOG4108YXA	Membrane
CEW87_04810	ENOG4105D58	Diguanylate phosphodiesterase
CEW87_04815	ENOG4105BZU	Histidine kinase
CEW87_04820	ENOG4105BZU	Histidine kinase
CEW87_04825	ENOG4105W2Z	cytochrome C, class I
CEW87_04840	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CEW87_04855	ENOG4105CPD	ethanolamine ammonia-lyase
CEW87_04860	ENOG4107FQ9	ethanolamine ammonia-lyase
CEW87_04870	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
CEW87_04875	ENOG4108WKG	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
CEW87_04880	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
CEW87_04885	ENOG4105CQM	Urea amidohydrolase subunit alpha
CEW87_04890	ENOG4105KI2	Urea amidohydrolase subunit beta
CEW87_04900	ENOG4108YZ9	Urea amidohydrolase subunit gamma
CEW87_04905	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
CEW87_04910	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
CEW87_04915	ENOG4105CHH	sulfate transporter
CEW87_04925	ENOG4107XWS	modD protein
CEW87_04930	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
CEW87_04935	ENOG4105E0C	molybdate abc transporter
CEW87_04940	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
CEW87_04945	ENOG4105F4R	Transcriptional regulator mode
CEW87_04950	ENOG4105F4R	Transcriptional regulator mode
CEW87_04970	ENOG4105D7T	ABC transporter
CEW87_04975	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
CEW87_04985	ENOG4105BZU	Histidine kinase
CEW87_04995	ENOG4108IV0	ABC, transporter
CEW87_05000	ENOG4105C0Z	ABC transporter
CEW87_05010	ENOG4105C32	Amino acid ABC transporter (Permease)
CEW87_05015	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
CEW87_05035	ENOG4105C1J	atp-dependent rna helicase
CEW87_05045	ENOG4108VKG	metal-dependent hydrolase
CEW87_05050	ENOG4105BZ1	(ABC) transporter
CEW87_05055	ENOG4105DC8	reductase
CEW87_05060	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CEW87_05065	ENOG4105BZU	Histidine kinase
CEW87_05070	ENOG4105DFG	type I secretion outer membrane protein
CEW87_05080	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
CEW87_05095	ENOG4105WH1	Two component transcriptional regulator luxr family
CEW87_05105	ENOG4108JJA	ABC, transporter
CEW87_05125	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CEW87_05135	ENOG4105MYN	Zinc uptake regulation protein
CEW87_05140	ENOG4105DIK	(ABC) transporter
CEW87_05145	ENOG4105CC5	ABC transporter
CEW87_05150	ENOG4105DSE	periplasmic solute binding protein
CEW87_05155	ENOG4107QYX	exodeoxyribonuclease v alpha
CEW87_05160	ENOG4107QKA	exodeoxyribonuclease V beta
CEW87_05165	ENOG4105DJ4	phosphatidylserine decarboxylase
CEW87_05170	ENOG4105DSY	exodeoxyribonuclease V, gamma
CEW87_05175	ENOG4105VRT	cytoplasmic protein
CEW87_05180	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
CEW87_05190	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
CEW87_05200	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
CEW87_05205	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CEW87_05210	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
CEW87_05215	ENOG4105BZS	acriflavin resistance protein
CEW87_05220	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
CEW87_05225	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
CEW87_05230	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
CEW87_05250	ENOG4105EYH	Exonuclease
CEW87_05255	ENOG4107RFY	SbcCD D subunit
CEW87_05270	ENOG410904N	short-chain dehydrogenase reductase
CEW87_05295	ENOG4105D07	Signal peptide peptidase, SppA
CEW87_05300	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
CEW87_05305	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
CEW87_05310	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
CEW87_05315	ENOG4105DWV	Homoserine O-trans-acetylase
CEW87_05325	ENOG4105CDA	abc transporter atp-binding protein
CEW87_05330	ENOG4105DRP	amino acid AbC transporter
CEW87_05335	ENOG4105EZ7	amino acid ABC transporter
CEW87_05350	ENOG4105BZU	Histidine kinase
CEW87_05355	ENOG4105EYM	Major Facilitator superfamily
CEW87_05375	ENOG41077A9	carbonic anhydrase
CEW87_05380	ENOG4105DKQ	ROK family
CEW87_05385	ENOG4105C25	Primosomal protein n'
CEW87_05390	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
CEW87_05395	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
CEW87_05400	ENOG4105C1A	potassium transporter peripheral membrane
CEW87_05405	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CEW87_05410	ENOG4105ES5	Histidine kinase
CEW87_05420	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
CEW87_05430	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
CEW87_05440	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
CEW87_05445	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CEW87_05450	ENOG4105X5M	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
CEW87_05460	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
CEW87_05465	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
CEW87_05470	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CEW87_05510	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
CEW87_05515	ENOG4105NI8	Cytosine-specific methyltransferase
CEW87_05560	ENOG4108UK2	deaminase
CEW87_05590	ENOG4105G2Y	Transcriptional regulator
CEW87_05595	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
CEW87_05600	ENOG4105CZK	Aspartate kinase
CEW87_05605	ENOG4105DG4	malate L-lactate dehydrogenase
CEW87_05610	ENOG4105DA5	(ABC) transporter
CEW87_05615	ENOG4105E3A	(ABC) transporter
CEW87_05625	ENOG4105BZU	Histidine kinase
CEW87_05630	ENOG4105ETT	transcriptional Regulator, LysR family
CEW87_05660	ENOG4105QNF	Outer membrane lipoprotein
CEW87_05675	ENOG4105BZU	Histidine kinase
CEW87_05695	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CEW87_05705	ENOG4105F38	ABC transporter, permease
CEW87_05710	ENOG4105D38	putrescine abc transporter
CEW87_05715	ENOG4105C26	Dehydrogenase
CEW87_05720	ENOG4108JPW	Aminotransferase
CEW87_05725	ENOG4105EE5	Membrane protein terC
CEW87_05730	ENOG4105E7W	lamb ycsf family protein
CEW87_05735	ENOG4107R7A	Allophanate hydrolase subunit 2
CEW87_05740	ENOG4105P4J	Allophanate hydrolase, subunit 1
CEW87_05760	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CEW87_05775	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
CEW87_05780	ENOG4105C0H	protease
CEW87_05785	ENOG4105BZU	Histidine kinase
CEW87_05790	ENOG4108NVR	Methyl-accepting chemotaxis
CEW87_05795	ENOG4105KA7	cytochrome C
CEW87_05805	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
CEW87_05815	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
CEW87_05835	ENOG4105DH7	May be involved in recombination (By similarity)
CEW87_05840	ENOG4105C0A	alcohol dehydrogenase
CEW87_05845	ENOG4105C26	Dehydrogenase
CEW87_05855	ENOG4105C0A	alcohol dehydrogenase
CEW87_05860	ENOG4108IV0	ABC, transporter
CEW87_05865	ENOG4108IUZ	ABC transporter
CEW87_05875	ENOG4105C32	Amino acid ABC transporter (Permease)
CEW87_05890	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CEW87_05895	ENOG4105BZU	Histidine kinase
CEW87_05905	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
CEW87_05910	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CEW87_05915	ENOG4108RPN	Protein smg homolog
CEW87_05920	ENOG4105C79	DNA protecting protein DprA
CEW87_05930	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
CEW87_05935	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
CEW87_05940	ENOG4105D0M	Protease HtpX homolog
CEW87_05945	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CEW87_05950	ENOG4108KS2	transglutaminase domain protein
CEW87_05960	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
CEW87_05965	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
CEW87_05970	ENOG4105BZU	Histidine kinase
CEW87_05975	ENOG4105BZU	Histidine kinase
CEW87_05990	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
CEW87_06010	ENOG4105FYV	Amp nucleosidase
CEW87_06020	ENOG4105E3J	oxidoreductase
CEW87_06030	ENOG4107YNJ	LysR family Transcriptional regulator
CEW87_06035	ENOG4105D82	Glutamate dehydrogenase
CEW87_06040	ENOG4105CM2	brancheD-chain amino acid aminotransferase
CEW87_06045	ENOG4105ETT	transcriptional Regulator, LysR family
CEW87_06065	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
CEW87_06070	ENOG41060NI	Is required to sustain N(2)-dependent growth in the presence of low levels of carbon monoxide (CO). Probably acts by protecting the N(2) fixation ability of the nitrogenase complex, which is inactivated in the presence of CO
CEW87_06085	ENOG4107RZC	phospholipase d
CEW87_06090	ENOG4105CAU	Arsenical resistance protein, ArsH
CEW87_06095	ENOG4105K89	arsenate reductase
CEW87_06115	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CEW87_06145	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
CEW87_06150	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CEW87_06155	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CEW87_06160	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
CEW87_06170	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
CEW87_06175	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
CEW87_06195	ENOG4105DND	Transcriptional regulator
CEW87_06200	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CEW87_06210	ENOG4105BZU	Histidine kinase
CEW87_06235	ENOG4105CH5	extracellular solute-binding protein, family 7
CEW87_06245	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CEW87_06275	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
CEW87_06300	ENOG4105QVC	MOSC domain-containing protein
CEW87_06305	ENOG4105BZU	Histidine kinase
CEW87_06330	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
CEW87_06375	ENOG4108JUA	Transcriptional regulator
CEW87_06395	ENOG4105I5W	Transporter
CEW87_06405	ENOG4105D7T	ABC transporter
CEW87_06410	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
CEW87_06425	ENOG4105J0Q	Transcriptional regulator
CEW87_06430	ENOG4105DXC	membrane
CEW87_06435	ENOG41083Z3	extracellular ligand-binding receptor
CEW87_06440	ENOG4105BZU	Histidine kinase
CEW87_06445	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CEW87_06450	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
CEW87_06455	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
CEW87_06460	ENOG4107QJE	Chromosome Partitioning Protein
CEW87_06465	ENOG4105FA0	parb-like partition protein
CEW87_06490	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
CEW87_06495	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CEW87_06500	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CEW87_06505	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CEW87_06510	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
CEW87_06515	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
CEW87_06520	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
CEW87_06525	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
CEW87_06540	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CEW87_06550	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CEW87_06555	ENOG4105BZU	Histidine kinase
CEW87_06570	ENOG4105E7A	Glutamine amidotransferase
CEW87_06575	ENOG4105CUC	YeeE YedE family protein
CEW87_06585	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
CEW87_06595	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
CEW87_06600	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
CEW87_06605	ENOG4105DFF	Rod shape-determining protein mreb
CEW87_06620	ENOG4105CJN	penicillin-binding protein
CEW87_06625	ENOG4105CNI	cell division protein FtsW
CEW87_06635	ENOG4105DZ1	carboxypeptidase
CEW87_06640	ENOG4105F0I	Aminotransferase
CEW87_06645	ENOG4108Z43	UPF0250 protein
CEW87_06650	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
CEW87_06655	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
CEW87_06670	ENOG4105C4R	Atp-dependent dna helicase
CEW87_06680	ENOG4105BZU	Histidine kinase
CEW87_06685	ENOG4105E4C	Lytic transglycosylase catalytic
CEW87_06695	ENOG4107R50	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
CEW87_06710	ENOG4108WUH	Transcriptional regulator, TetR family
CEW87_06715	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
CEW87_06760	ENOG4107RUY	(E1 component), alpha subunit
CEW87_06765	ENOG4105CPP	Dehydrogenase, E1 component
CEW87_06775	ENOG4107QKR	Dehydrogenase
CEW87_06780	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
CEW87_06805	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
CEW87_06820	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
CEW87_06825	ENOG4105CSV	Glutaminase
CEW87_06855	ENOG4105CPQ	Dehydrogenase
CEW87_06865	ENOG41065RQ	ADP-ribosylation crystallin J1
CEW87_06955	ENOG4108YYH	Nadph-dependent fmn reductase
CEW87_06965	ENOG4105ETT	transcriptional Regulator, LysR family
CEW87_06980	ENOG4105C94	Transporter
CEW87_06985	ENOG4105CJP	fad dependent oxidoreductase
CEW87_06995	ENOG4107QPK	)-transporter
CEW87_07015	ENOG4106DSS	Tartrate dehydratase subunit alpha
CEW87_07035	ENOG4105C26	Dehydrogenase
CEW87_07040	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CEW87_07055	ENOG4105C0A	alcohol dehydrogenase
CEW87_07090	ENOG4105HDD	phospholipase
CEW87_07095	ENOG4105D64	Mechanosensitive ion channel
CEW87_07150	ENOG4105FB9	CRISPR-associated protein
CEW87_07170	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
CEW87_07175	ENOG4105KCF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
CEW87_07195	ENOG4105VTR	Integrase
CEW87_07215	ENOG4105CSA	Coproporphyrinogen iii oxidase
CEW87_07220	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
CEW87_07225	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
CEW87_07235	ENOG4105D9P	serine threonine protein kinase
CEW87_07240	ENOG4105DSJ	YicC domain protein
CEW87_07245	ENOG4108594	Permease of the drug metabolite transporter
CEW87_07260	ENOG4105DCY	Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity)
CEW87_07275	ENOG4108IV0	ABC, transporter
CEW87_07280	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
CEW87_07290	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
CEW87_07295	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
CEW87_07300	ENOG4105BZU	Histidine kinase
CEW87_07305	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CEW87_07310	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
CEW87_07315	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
CEW87_07320	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
CEW87_07330	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CEW87_07335	ENOG4105DKD	Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity)
CEW87_07340	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
CEW87_07345	ENOG4105BZU	Histidine kinase
CEW87_07350	ENOG4105WH1	Two component transcriptional regulator luxr family
CEW87_07365	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
CEW87_07370	ENOG4108BGM	Quinol dehydrogenase periplasmic component
CEW87_07375	ENOG4105GXZ	Ferredoxin-type protein NapH
CEW87_07385	ENOG4105CUW	cytochrome C-TYPE protein
CEW87_07390	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
CEW87_07395	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
CEW87_07400	ENOG41060IM	Heme exporter protein
CEW87_07410	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
CEW87_07415	ENOG4105DA4	cytochrome c-type biogenesis protein
CEW87_07420	ENOG4107QX9	Thiol disulfide interChange protein
CEW87_07425	ENOG4105KWW	Biogenesis protein
CEW87_07430	ENOG4108M1T	Cytochrome c-type biogenesis protein
CEW87_07435	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
CEW87_07440	ENOG4107SDU	Methyl-accepting chemotaxis
CEW87_07470	ENOG4105BZU	Histidine kinase
CEW87_07495	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CEW87_07500	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
CEW87_07505	ENOG4108ZJ4	polysaccharide deacetylase
CEW87_07510	ENOG4105D78	K07001 NTE family protein
CEW87_07570	ENOG4105CJ1	ABC, transporter
CEW87_07585	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
CEW87_07635	ENOG4108UKI	Enoyl-CoA hydratase
CEW87_07640	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
CEW87_07645	ENOG4108ZJI	phenylacetic acid degradation protein
CEW87_07655	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
CEW87_07660	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
CEW87_07665	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
CEW87_07670	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
CEW87_07675	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
CEW87_07685	ENOG4105CHU	acetyl-coa acetyltransferase
CEW87_07700	ENOG4105C0Z	ABC transporter
CEW87_07705	ENOG4108IV0	ABC, transporter
CEW87_07715	ENOG4105K70	DNA-binding protein
CEW87_07720	ENOG4105C1J	atp-dependent rna helicase
CEW87_07725	ENOG4107YIM	Involved in the transcription termination process (By similarity)
CEW87_07730	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
CEW87_07735	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
CEW87_07745	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
CEW87_07775	ENOG4105BZU	Histidine kinase
CEW87_07780	ENOG4105BZU	Histidine kinase
CEW87_07785	ENOG4107R73	Mate efflux family protein
CEW87_07800	ENOG4105EZR	dyp-type peroxidase family protein
CEW87_07805	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
CEW87_07820	ENOG4107RSM	transcriptional regulator
CEW87_07825	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
CEW87_07830	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
CEW87_07835	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
CEW87_07840	ENOG4105C4R	Atp-dependent dna helicase
CEW87_07870	ENOG4105BZU	Histidine kinase
CEW87_07875	ENOG4105BZU	Histidine kinase
CEW87_07900	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
CEW87_07905	ENOG4107RCH	Diaminopropionate ammonia-lyase
CEW87_07910	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
CEW87_07915	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CEW87_07930	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
CEW87_07955	ENOG4107RK0	Sucrose phosphorylase
CEW87_07965	ENOG4106TD9	Diguanylate cyclase
CEW87_07975	ENOG4105C4R	Atp-dependent dna helicase
CEW87_08000	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
CEW87_08005	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
CEW87_08010	ENOG4105W3S	hemerythrin-like, metal-binding protein
CEW87_08015	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
CEW87_08025	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
CEW87_08030	ENOG4105MP9	class II Aldolase
CEW87_08040	ENOG4105C26	Dehydrogenase
CEW87_08060	ENOG4107THI	3,4-dihydroxyphenylacetate 2,3-dioxygenase
CEW87_08065	ENOG4105C26	Dehydrogenase
CEW87_08080	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CEW87_08090	ENOG4105K56	Transcriptional regulator
CEW87_08105	ENOG4105E39	Enoyl-CoA hydratase
CEW87_08110	ENOG4105CD5	CoA-binding domain protein
CEW87_08115	ENOG4105E39	Enoyl-CoA hydratase
CEW87_08120	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
CEW87_08130	ENOG4107QS8	(LipO)protein
CEW87_08135	ENOG4105CJ1	ABC, transporter
CEW87_08140	ENOG4108U78	Glutathione S-transferase
CEW87_08145	ENOG4107U2T	alpha beta
CEW87_08165	ENOG41063Z6	transcriptional regulator, lysR family
CEW87_08190	ENOG4105DHQ	Histidine kinase
CEW87_08210	ENOG4108YZA	Nitrogen regulatory protein pii
CEW87_08215	ENOG4105BZU	Histidine kinase
CEW87_08240	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
CEW87_08250	ENOG4105CFQ	glutamine synthetase
CEW87_08255	ENOG4105EYU	Glutamine amido-transferase
CEW87_08265	ENOG4105CBC	glutamate synthase
CEW87_08270	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
CEW87_08290	ENOG4105E3J	oxidoreductase
CEW87_08300	ENOG4105C1G	acyl-Coa dehydrogenase
CEW87_08310	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
CEW87_08320	ENOG4105BZU	Histidine kinase
CEW87_08325	ENOG4105WH1	Two component transcriptional regulator luxr family
CEW87_08340	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
CEW87_08345	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
CEW87_08355	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CEW87_08365	ENOG4105CH5	extracellular solute-binding protein, family 7
CEW87_08380	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
CEW87_08390	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CEW87_08395	ENOG4105XPQ	lipid carrier protein
CEW87_08400	ENOG4106RZ4	Peptidase U32
CEW87_08405	ENOG4105CFP	Peptidase U32
CEW87_08415	ENOG4105C8Y	Acetylornithine aminotransferase
CEW87_08420	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
CEW87_08425	ENOG4105C75	arginyL-tRNA synthetase
CEW87_08435	ENOG4108Z33	Thiol disulfide Interchange Protein
CEW87_08440	ENOG4107FW0	short-chain dehydrogenase reductase
CEW87_08460	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
CEW87_08470	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
CEW87_08480	ENOG4108Z6Z	Transcriptional regulator
CEW87_08490	ENOG41077A9	carbonic anhydrase
CEW87_08495	ENOG4105CHU	acetyl-coa acetyltransferase
CEW87_08500	ENOG4105C1G	acyl-Coa dehydrogenase
CEW87_08510	ENOG4108MEJ	flavin reductase domain protein
CEW87_08515	ENOG4105BZU	Histidine kinase
CEW87_08535	ENOG4108IND	Tetr family transcriptional regulator
CEW87_08550	ENOG4105CYM	Glutathione S-transferase
CEW87_08570	ENOG4105C1G	acyl-Coa dehydrogenase
CEW87_08585	ENOG4107QX3	carboxylase
CEW87_08590	ENOG4105CGU	Enoyl-CoA hydratase
CEW87_08600	ENOG4105CEY	Amp-dependent synthetase and ligase
CEW87_08605	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
CEW87_08625	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
CEW87_08645	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
CEW87_08650	ENOG4108URH	decarboxylase
CEW87_08660	ENOG4107U4J	modification
CEW87_08675	ENOG4108IV0	ABC, transporter
CEW87_08680	ENOG4105C0Z	ABC transporter
CEW87_08685	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
CEW87_08690	ENOG4105C32	Amino acid ABC transporter (Permease)
CEW87_08700	ENOG4105C26	Dehydrogenase
CEW87_08705	ENOG4105EW9	transcriptional regulator AsnC family
CEW87_08710	ENOG4105D7Z	glutathione synthase
CEW87_08715	ENOG41081YB	ApbE family
CEW87_08725	ENOG4105FDR	Membrane
CEW87_08735	ENOG4105CPI	Metal Dependent Phosphohydrolase
CEW87_08740	ENOG4105ECA	phosphoserine phosphatase homoserine phosphotransferase bifunctional protein
CEW87_08745	ENOG4105CIY	formyltetrahydrofolate deformylase
CEW87_08750	ENOG4105BZU	Histidine kinase
CEW87_08755	ENOG4108YZA	Nitrogen regulatory protein pii
CEW87_08770	ENOG4105C0P	Mg chelatase subunit ChlI
CEW87_08795	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
CEW87_08840	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
CEW87_08885	ENOG4105C0P	Mg chelatase subunit ChlI
CEW87_08895	ENOG4105C2C	drug resistance transporter, Bcr CflA
CEW87_08910	ENOG4108IV0	ABC, transporter
CEW87_08915	ENOG4105C0Z	ABC transporter
CEW87_08920	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
CEW87_08925	ENOG4105C32	Amino acid ABC transporter (Permease)
CEW87_08930	ENOG4105CP9	extracellular ligand-binding receptor
CEW87_08935	ENOG4105CP9	extracellular ligand-binding receptor
CEW87_08950	ENOG4105CS6	Rhs element vgr protein
CEW87_08990	ENOG4105C3R	Methionine synthase
CEW87_09025	ENOG4105CB2	alcohol dehydrogenase
CEW87_09045	ENOG4105NAF	rna polymerase sigma factor
CEW87_09060	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
CEW87_09065	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
CEW87_09070	ENOG4105C26	Dehydrogenase
CEW87_09115	ENOG4105KAC	Antibiotic biosynthesis monooxygenase
CEW87_09135	ENOG4105EWC	Purine nucleoside phosphorylase
CEW87_09140	ENOG4105KPY	Small multidrug resistance protein
CEW87_09150	ENOG4105EJC	lysr family transcriptional regulator
CEW87_09155	ENOG41080RH	Thioredoxin
CEW87_09165	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
CEW87_09170	ENOG4105EHZ	conserved protein UCP016719
CEW87_09205	ENOG4105C31	Tryptophanyl-tRNA synthetase
CEW87_09215	ENOG4105D4A	Cell wall formation (By similarity)
CEW87_09220	ENOG4107BJW	polysaccharide deacetylase
CEW87_09260	ENOG4105BZ1	(ABC) transporter
CEW87_09270	ENOG4107G9V	glycosyl transferase, family 39
CEW87_09275	ENOG4105D16	lipopolysaccharide heptosyltransferase i
CEW87_09280	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
CEW87_09285	ENOG4107TYR	Glycosyl Transferase
CEW87_09290	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
CEW87_09305	ENOG4105C01	Dihydroxy-acid dehydratase
CEW87_09335	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
CEW87_09340	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
CEW87_09345	ENOG4105C08	Histidine kinase
CEW87_09360	ENOG4105F4R	Transcriptional regulator mode
CEW87_09370	ENOG4105C5X	domain protein
CEW87_09375	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
CEW87_09380	ENOG4105EN6	Membrane
CEW87_09390	ENOG4105C32	Amino acid ABC transporter (Permease)
CEW87_09395	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
CEW87_09405	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
CEW87_09420	ENOG4105CEN	a g-specific adenine glycosylase
CEW87_09430	ENOG4105BZU	Histidine kinase
CEW87_09445	ENOG4105BZ1	(ABC) transporter
CEW87_09450	ENOG4105CPK	Glycosyl transferase (Group 1
CEW87_09470	ENOG4108SHN	Glycosyl transferase, family 2
CEW87_09485	ENOG4105E0M	Sulfatase
CEW87_09500	ENOG4107543	(lipo)polysaccharide
CEW87_09505	ENOG4107RJ7	Glycosyl transferase (Group 1
CEW87_09510	ENOG4105D16	lipopolysaccharide heptosyltransferase i
CEW87_09515	ENOG4105XA0	heptosyltransferase ii
CEW87_09520	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
CEW87_09525	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
CEW87_09535	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
CEW87_09540	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
CEW87_09545	ENOG4108YZT	Adenosylcobinamide kinase
CEW87_09550	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
CEW87_09555	ENOG4105EHG	Permease protein
CEW87_09560	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
CEW87_09565	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
CEW87_09570	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
CEW87_09575	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
CEW87_09580	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
CEW87_09600	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
CEW87_09605	ENOG41080Z8	PHOSPHOCARRIER protein
CEW87_09610	ENOG4108YTN	IIa component
CEW87_09615	ENOG4105CVI	Transcriptional regulator
CEW87_09625	ENOG4105CDV	Ompa motb domain protein
CEW87_09630	ENOG4105CJ3	phosphate transporter
CEW87_09645	ENOG4105BZU	Histidine kinase
CEW87_09650	ENOG4105C5H	ABC transporter
CEW87_09665	ENOG4105CFP	Peptidase U32
CEW87_09675	ENOG4105DHI	Methyltransferase
CEW87_09695	ENOG4109066	lysm domain bon superfamily protein
CEW87_09705	ENOG4105BZU	Histidine kinase
CEW87_09710	ENOG4105BZU	Histidine kinase
CEW87_09715	ENOG4107RUE	extracellular solute-binding protein family 1
CEW87_09720	ENOG4105BZU	Histidine kinase
CEW87_09725	ENOG4105BZU	Histidine kinase
CEW87_09730	ENOG4108UPT	UPF0178 protein
CEW87_09735	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
CEW87_09750	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
CEW87_09755	ENOG4105E39	Enoyl-CoA hydratase
CEW87_09765	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
CEW87_09770	ENOG4107VRB	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
CEW87_09780	ENOG4105KCK	Peptidoglycan-associated lipoprotein
CEW87_09785	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
CEW87_09795	ENOG4105M8F	Biopolymer transport protein exbD tolR
CEW87_09800	ENOG4105E02	MotA TolQ exbB proton channel
CEW87_09805	ENOG4107YD3	Thioesterase
CEW87_09815	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
CEW87_09820	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
CEW87_09830	ENOG4105BZU	Histidine kinase
CEW87_09835	ENOG4105VEJ	Heat shock protein
CEW87_09855	ENOG4105CE1	Ferrous iron transport protein b
CEW87_09860	ENOG4107E2E	PKHD-type hydroxylase
CEW87_09870	ENOG4108ESX	Receptor
CEW87_09880	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CEW87_09885	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
CEW87_09905	ENOG4108UQY	Iron-storage protein
CEW87_09915	ENOG4107F3C	Hemin uptake protein
CEW87_09940	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
CEW87_09945	ENOG4108YXG	UPF0502 protein
CEW87_09950	ENOG4108T5G	Adenylate
CEW87_09980	ENOG41080IJ	Diacylglycerol kinase
CEW87_09990	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
CEW87_09995	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
CEW87_10000	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
CEW87_10005	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
CEW87_10010	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CEW87_10020	ENOG4105DFU	Cell wall formation (By similarity)
CEW87_10030	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
CEW87_10035	ENOG41082RQ	UPF0102 protein
CEW87_10040	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
CEW87_10045	ENOG4105EKE	dihydroorotase
CEW87_10060	ENOG4108V6E	Cell division protein mraZ
CEW87_10065	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
CEW87_10075	ENOG4105CJN	penicillin-binding protein
CEW87_10080	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
CEW87_10085	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
CEW87_10090	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
CEW87_10095	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
CEW87_10100	ENOG4105CNI	cell division protein FtsW
CEW87_10105	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
CEW87_10110	ENOG4105DFU	Cell wall formation (By similarity)
CEW87_10115	ENOG4105CPF	Cell wall formation (By similarity)
CEW87_10120	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
CEW87_10125	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
CEW87_10130	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
CEW87_10135	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CEW87_10150	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
CEW87_10155	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
CEW87_10160	ENOG4105DFH	Transport of potassium into the cell (By similarity)
CEW87_10165	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
CEW87_10175	ENOG4105NWN	ApaG protein
CEW87_10180	ENOG4107QTF	adenylosuccinate lyase
CEW87_10190	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CEW87_10195	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CEW87_10200	ENOG4105VIE	preprotein translocase, subunit YajC
CEW87_10205	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
CEW87_10210	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
CEW87_10220	ENOG41063Z6	transcriptional regulator, lysR family
CEW87_10230	ENOG4108MN8	Membrane
CEW87_10235	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
CEW87_10240	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
CEW87_10250	ENOG4105BZU	Histidine kinase
CEW87_10255	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
CEW87_10260	ENOG4108RA0	tripartite ATP-independent periplasmic transporter, DctQ component
CEW87_10265	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CEW87_10270	ENOG4105FE9	pseudouridine synthase
CEW87_10280	ENOG4105DU1	integral membrane protein, terc
CEW87_10295	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CEW87_10300	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CEW87_10305	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CEW87_10315	ENOG4105CX6	glutaminyL-tRNA synthetase
CEW87_10320	ENOG4105D64	Mechanosensitive ion channel
CEW87_10330	ENOG4108WHA	ompa motb domain protein
CEW87_10345	ENOG4105HKX	acetone carboxylase, gamma subunit
CEW87_10350	ENOG4107TYC	hydantoinase B oxoprolinase
CEW87_10355	ENOG4107RID	5-oxoprolinase (ATP-hydrolyzing)
CEW87_10360	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
CEW87_10365	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
CEW87_10370	ENOG4105DWF	phosphomethylpyrimidine kinase
CEW87_10380	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CEW87_10405	ENOG4108QV3	biosynthesis protein
CEW87_10420	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
CEW87_10445	ENOG4105CAQ	asparagine synthetase
CEW87_10450	ENOG4105E2K	Glycosyl transferase (Group 1
CEW87_10455	ENOG4105CAQ	asparagine synthetase
CEW87_10465	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
CEW87_10525	ENOG4108MX3	Polysaccharide Biosynthesis Protein
CEW87_10540	ENOG4105K64	Glycosyl transferase, family 2
CEW87_10580	ENOG4105K4U	addiction module toxin, RelE StbE family
CEW87_10590	ENOG4105CAQ	asparagine synthetase
CEW87_10615	ENOG4105CEY	Amp-dependent synthetase and ligase
CEW87_10635	ENOG4105CAS	nag kinase
CEW87_10640	ENOG4105VN1	Heat shock protein
CEW87_10660	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CEW87_10665	ENOG4107Z67	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
CEW87_10675	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
CEW87_10685	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
CEW87_10690	ENOG4105C6K	Malic enzyme
CEW87_10700	ENOG41061WM	D-Alanyl-D-Alanine
CEW87_10710	ENOG4105D65	subunit l
CEW87_10715	ENOG4108ZE9	Monovalent cation H antiporter subunit C
CEW87_10720	ENOG4107R4Z	monovalent cation h antiporter subunit d
CEW87_10725	ENOG4105SC1	monovalent cation H antiporter subunit E
CEW87_10730	ENOG4105W4C	monovalent cation H antiporter subunit F
CEW87_10735	ENOG4105KJM	monovalent cation h antiporter subunit g
CEW87_10740	ENOG4105KJM	monovalent cation h antiporter subunit g
CEW87_10750	ENOG4105SC1	monovalent cation H antiporter subunit E
CEW87_10755	ENOG4108JPZ	Monovalent cation H antiporter subunit D
CEW87_10765	ENOG4105D65	subunit l
CEW87_10770	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
CEW87_10775	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CEW87_10785	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
CEW87_10790	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
CEW87_10795	ENOG4105CUT	histidyl-tRNA synthetase
CEW87_10805	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
CEW87_10810	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
CEW87_10815	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
CEW87_10820	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
CEW87_10825	ENOG4107QJR	hflk protein
CEW87_10830	ENOG4105EPW	hflc protein
CEW87_10840	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
CEW87_10845	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
CEW87_10860	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
CEW87_10865	ENOG4105C2N	RNA methyltransferase TrmH family group 3
CEW87_10890	ENOG4105D7T	ABC transporter
CEW87_10895	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
CEW87_10900	ENOG4108IFG	nitrite reductase, (NAD(P)H)
CEW87_10915	ENOG41080XP	Cbs domain
CEW87_10920	ENOG4105C94	Transporter
CEW87_10930	ENOG4108DBC	nitroreductase
CEW87_10945	ENOG4107QMP	dna polymerase iii subunits gamma and tau
CEW87_10950	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
CEW87_10955	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
CEW87_10960	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
CEW87_10965	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
CEW87_10970	ENOG4105EIX	cytochrome c1
CEW87_10975	ENOG4107MKT	Stringent starvation protein a
CEW87_10980	ENOG4105KB2	stringent starvation protein b
CEW87_10985	ENOG4105BZF	Glycosyl transferase (Group 1
CEW87_10995	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
CEW87_11000	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CEW87_11010	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
CEW87_11015	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
CEW87_11020	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
CEW87_11025	ENOG4105DHQ	Histidine kinase
CEW87_11030	ENOG41062QD	Membrane
CEW87_11040	ENOG4105DHQ	Histidine kinase
CEW87_11055	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
CEW87_11060	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
CEW87_11075	ENOG4105C7I	Dehydrogenase
CEW87_11080	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
CEW87_11085	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
CEW87_11090	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
CEW87_11120	ENOG4105D9P	serine threonine protein kinase
CEW87_11125	ENOG4105CH7	arginosuccinase
CEW87_11130	ENOG4108NEV	two component transcriptional regulator, LytTR family
CEW87_11170	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
CEW87_11180	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
CEW87_11185	ENOG41076E6	Uroporphyrinogen-III Synthase
CEW87_11190	ENOG4105ECF	c-methyltransferase
CEW87_11200	ENOG4105CHH	sulfate transporter
CEW87_11205	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
CEW87_11220	ENOG4105DHP	deoxycytidine triphosphate deaminase
CEW87_11225	ENOG4105CXN	decarboxylase
CEW87_11235	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
CEW87_11285	ENOG4105XV5	nifz family
CEW87_11290	ENOG410605C	May protect the nitrogenase Fe-Mo protein from oxidative damage (By similarity)
CEW87_11305	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
CEW87_11310	ENOG4105C3J	Cysteine desulfurase
CEW87_11315	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
CEW87_11320	ENOG4105QAS	Iron-sulfur cluster assembly accessory protein
CEW87_11350	ENOG4108UR2	Nitrogen fixation protein NifX
CEW87_11355	ENOG4105DK8	Nitrogenase molybdenum-iron cofactor biosynthesis protein NifN
CEW87_11360	ENOG4105D0B	Nitrogenase protein alpha chain
CEW87_11380	ENOG4105NZG	Ferredoxin
CEW87_11385	ENOG4108TGK	Low-potential electron donor to a number of redox enzymes (By similarity)
CEW87_11395	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
CEW87_11445	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
CEW87_11450	ENOG4105K8R	UPF0145 protein
CEW87_11460	ENOG4105CDY	transcriptional regulatory protein
CEW87_11465	ENOG4105D7A	ATP-binding protein
CEW87_11470	ENOG4106UX7	integral membrane protein
CEW87_11475	ENOG4108W2P	Methyl-accepting chemotaxis
CEW87_11480	ENOG4105SYT	Methylenetetrahydrofolate reductase
CEW87_11485	ENOG4105DX0	Hemolysin A
CEW87_11490	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
CEW87_11495	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
CEW87_11500	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
CEW87_11510	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
CEW87_11520	ENOG4105D1S	lipid A biosynthesis
CEW87_11530	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
CEW87_11540	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CEW87_11550	ENOG4105DR4	Methyltransferase
CEW87_11560	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
CEW87_11565	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
CEW87_11570	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
CEW87_11580	ENOG4105C03	ribonuclease
CEW87_11585	ENOG4108Z03	MAF-like protein
CEW87_11590	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
CEW87_11595	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
CEW87_11600	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
CEW87_11615	ENOG4105CUV	Homoserine Kinase
CEW87_11630	ENOG4108URH	decarboxylase
CEW87_11635	ENOG4105C2M	dna polymerase I
CEW87_11640	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
CEW87_11645	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
CEW87_11655	ENOG4105D2T	synthase
CEW87_11660	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
CEW87_11665	ENOG4108MCH	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
CEW87_11710	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CEW87_11720	ENOG4108UW5	maltose o-acetyltransferase
CEW87_11725	ENOG4105EVB	acetyltransferase
CEW87_11740	ENOG4108IAJ	Nad-dependent epimerase dehydratase
CEW87_11745	ENOG4105K64	Glycosyl transferase, family 2
CEW87_11750	ENOG4108RJ9	Glycosyl transferase, family 2
CEW87_11755	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
CEW87_11760	ENOG4105D3Q	Sugar transferase
CEW87_11770	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
CEW87_11790	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
CEW87_11795	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
CEW87_11800	ENOG4105C2W	permease
CEW87_11820	ENOG4105CGK	Exodeoxyribonuclease III
CEW87_11825	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
CEW87_11835	ENOG4108J2R	molybdopterin oxidoreductase
CEW87_11840	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
CEW87_11850	ENOG4105M4H	endoribonuclease L-psp
CEW87_11855	ENOG4105W39	Membrane
CEW87_11870	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
CEW87_11890	ENOG410832A	alpha/beta hydrolase fold
CEW87_11895	ENOG4105CYM	Glutathione S-transferase
CEW87_11905	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CEW87_11920	ENOG4107SC1	transglycosylase
CEW87_11925	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
CEW87_11930	ENOG4105BZU	Histidine kinase
CEW87_11940	ENOG4105C7B	Threonine dehydratase
CEW87_11945	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
CEW87_11950	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
CEW87_11955	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
CEW87_11960	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CEW87_11965	ENOG4108IUZ	ABC transporter
CEW87_11970	ENOG4108004	Modulates RecA activity (By similarity)
CEW87_11975	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
CEW87_11980	ENOG4107TH8	cina domain protein
CEW87_11985	ENOG4108ZAI	phosphatidylglycerophosphatase a
CEW87_11990	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
CEW87_11995	ENOG4105BZU	Histidine kinase
CEW87_12010	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CEW87_12020	ENOG4105VCC	30S ribosomal protein S21
CEW87_12025	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CEW87_12030	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
CEW87_12045	ENOG4108Z66	YbaK ebsC protein
CEW87_12050	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CEW87_12055	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
CEW87_12060	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
CEW87_12065	ENOG4105DJF	DNA polymerase III, delta' subunit
CEW87_12075	ENOG4105C8T	Leucyl-tRNA synthetase
CEW87_12085	ENOG4105C4R	Atp-dependent dna helicase
CEW87_12090	ENOG4107QJE	Chromosome Partitioning Protein
CEW87_12095	ENOG4105C6K	Malic enzyme
CEW87_12105	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
CEW87_12115	ENOG4105C0B	DNA polymerase III (alpha subunit)
CEW87_12120	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
CEW87_12130	ENOG4105C12	Phosphoribosylglycinamide synthetase
CEW87_12135	ENOG4105DC1	bifunctional purine biosynthesis protein purh
CEW87_12140	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
CEW87_12145	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
CEW87_12150	ENOG4105D0A	hydroxylase
CEW87_12155	ENOG4107RAQ	aminopeptidase
CEW87_12160	ENOG4108S0S	Nucleotidyl transferase
CEW87_12165	ENOG4105EHM	Aminoglycoside phosphotransferase
CEW87_12170	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
CEW87_12175	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
CEW87_12180	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
CEW87_12185	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
CEW87_12220	ENOG4105DGW	oligopeptidase A
CEW87_12230	ENOG4105C8V	SAICAR synthetase
CEW87_12245	ENOG4108YYC	ycei family
CEW87_12255	ENOG4105DS1	cytochrome b561
CEW87_12260	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
CEW87_12270	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CEW87_12275	ENOG4105BZU	Histidine kinase
CEW87_12280	ENOG4105BZU	Histidine kinase
CEW87_12285	ENOG4105C7F	AcnD-accessory protein PrpF
CEW87_12290	ENOG4105EVD	ribosomal RNA large subunit methyltransferase N
CEW87_12305	ENOG4105D2N	Aldolase
CEW87_12310	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
CEW87_12320	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
CEW87_12335	ENOG4108VFZ	ribulose bisphosphate carboxylase, small
CEW87_12345	ENOG4105DUM	transcriptional regulator, lysR family
CEW87_12360	ENOG4105CA9	Pyruvate kinase
CEW87_12375	ENOG4105I8F	Histidine kinase
CEW87_12380	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CEW87_12390	ENOG4105UYK	outer membrane protein a
CEW87_12395	ENOG4105BZA	Phosphoglycerate kinase
CEW87_12405	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
CEW87_12410	ENOG4105CV1	Transketolase (EC 2.2.1.1)
CEW87_12425	ENOG4105ECY	inositol monophosphatase
CEW87_12430	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
CEW87_12435	ENOG4105CSR	polyphosphate kinase 2
CEW87_12440	ENOG4108EKC	n-acetylglutamate synthase
CEW87_12445	ENOG4105BZU	Histidine kinase
CEW87_12450	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
CEW87_12460	ENOG4105E66	phosphoriboisomerase A
CEW87_12465	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
CEW87_12470	ENOG4105ED9	Protein of unknown function (DUF455)
CEW87_12480	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
CEW87_12485	ENOG4105D52	delta-aminolevulinic acid dehydratase
CEW87_12495	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
CEW87_12500	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
CEW87_12505	ENOG4105MJ2	Competence protein
CEW87_12510	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
CEW87_12515	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
CEW87_12525	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
CEW87_12530	ENOG4105VW4	glutaredoxin 3
CEW87_12535	ENOG4107YZP	Rhodanese domain protein
CEW87_12540	ENOG41080HT	Transcriptional regulator, arsr family
CEW87_12545	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
CEW87_12555	ENOG4105CN1	protease
CEW87_12565	ENOG4105D06	uba thif-type nad fad binding protein
CEW87_12570	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
CEW87_12575	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
CEW87_12580	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
CEW87_12590	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CEW87_12600	ENOG4105CH5	extracellular solute-binding protein, family 7
CEW87_12605	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
CEW87_12615	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
CEW87_12620	ENOG4105UYK	outer membrane protein a
CEW87_12625	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
CEW87_12630	ENOG4105D9P	serine threonine protein kinase
CEW87_12635	ENOG41082T9	Membrane
CEW87_12640	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
CEW87_12645	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
CEW87_12650	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
CEW87_12655	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
CEW87_12660	ENOG41090R7	Ferric uptake
CEW87_12665	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
CEW87_12670	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
CEW87_12675	ENOG4105BZU	Histidine kinase
CEW87_12685	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
CEW87_12690	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
CEW87_12700	ENOG4105HBR	Rna-binding protein
CEW87_12705	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
CEW87_12710	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CEW87_12715	ENOG4105EEI	dihydropteroate synthase
CEW87_12720	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
CEW87_12725	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
CEW87_12730	ENOG4105C8U	phosphate abc transporter
CEW87_12735	ENOG4105E2Z	phosphate ABC transporter (Permease
CEW87_12740	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
CEW87_12750	ENOG4105CP7	Triose-phosphate isomerase
CEW87_12755	ENOG4107EJC	Preprotein translocase subunit SecG
CEW87_12765	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CEW87_12770	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CEW87_12775	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CEW87_12780	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CEW87_12785	ENOG4105GKE	subunit e
CEW87_12790	ENOG4107QIZ	NADH dehydrogenase
CEW87_12795	ENOG4108IEH	NADH dehydrogenase subunit g
CEW87_12800	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
CEW87_12805	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CEW87_12810	ENOG4105DF2	NADH dehydrogenase subunit j
CEW87_12815	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CEW87_12820	ENOG4105D65	subunit l
CEW87_12825	ENOG4105C8S	subunit m
CEW87_12830	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CEW87_12840	ENOG4105CSR	polyphosphate kinase 2
CEW87_12855	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
CEW87_12860	ENOG4105D0S	secretion protein (HlyD
CEW87_12865	ENOG4105CJ1	ABC, transporter
CEW87_12870	ENOG4105CMI	transporter
CEW87_12890	ENOG4107QX8	SPFH domain, Band 7 family protein
CEW87_12900	ENOG4105CDA	abc transporter atp-binding protein
CEW87_12905	ENOG4105E5Q	amino acid AbC transporter
CEW87_12925	ENOG4105BZU	Histidine kinase
CEW87_12950	ENOG4108YF6	methylamine dehydrogenase accessory protein MauD
CEW87_12965	ENOG4105D25	secreted protein
CEW87_12975	ENOG4107R13	MMPL domain protein
CEW87_12990	ENOG4105C26	Dehydrogenase
CEW87_12995	ENOG4108YXU	transcriptional regulator AsnC family
CEW87_13005	ENOG4107QP3	malate synthase g
CEW87_13015	ENOG4105DMF	Dehydrogenase
CEW87_13025	ENOG4105C34	Pseudouridine synthase
CEW87_13030	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
CEW87_13040	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
CEW87_13045	ENOG4105CHR	reductase
CEW87_13055	ENOG4108NVM	synthesis repressor PhaR
CEW87_13060	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
CEW87_13065	ENOG4105D78	K07001 NTE family protein
CEW87_13070	ENOG4105CQB	FAD linked oxidase domain protein
CEW87_13105	ENOG4108QDE	fad dependent oxidoreductase
CEW87_13110	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
CEW87_13115	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
CEW87_13120	ENOG4105K63	Thioredoxin
CEW87_13125	ENOG4108Z4U	Ferredoxin
CEW87_13135	ENOG4105CEY	Amp-dependent synthetase and ligase
CEW87_13140	ENOG4105C7K	acetolactate synthase
CEW87_13145	ENOG4105M71	acetolactate synthase 1 regulatory subunit
CEW87_13150	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
CEW87_13160	ENOG4105ERG	peptidase m48, ste24p
CEW87_13165	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CEW87_13170	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CEW87_13175	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
CEW87_13180	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
CEW87_13195	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
CEW87_13200	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
CEW87_13205	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
CEW87_13210	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
CEW87_13215	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
CEW87_13220	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
CEW87_13235	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
CEW87_13240	ENOG4105C28	cystathionine
CEW87_13245	ENOG4105CJW	magnesium transporter
CEW87_13255	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
CEW87_13260	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
CEW87_13265	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
CEW87_13270	ENOG4105C8N	cysteinyl-tRNA synthetase
CEW87_13280	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CEW87_13285	ENOG4105CFG	Acts as a chaperone (By similarity)
CEW87_13290	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CEW87_13295	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CEW87_13300	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
CEW87_13310	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CEW87_13320	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
CEW87_13325	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
CEW87_13330	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
CEW87_13340	ENOG4105CFV	Tetratricopeptide repeat protein
CEW87_13345	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
CEW87_13350	ENOG4105C6T	cysteine synthase
CEW87_13380	ENOG4105C22	threonyL-tRNA synthetase
CEW87_13385	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
CEW87_13390	ENOG4105VJV	50s ribosomal protein L35
CEW87_13395	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
CEW87_13400	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
CEW87_13405	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
CEW87_13410	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
CEW87_13430	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
CEW87_13440	ENOG4108IYC	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
CEW87_13445	ENOG4105EJQ	L-serine dehydratase
CEW87_13455	ENOG4105DPX	Hydrogenase, large subunit
CEW87_13475	ENOG4105X9Y	Hydrogenase assembly chaperone hypC hupF
CEW87_13490	ENOG4107UY0	rubredoxin
CEW87_13505	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
CEW87_13510	ENOG4107RSS	Hydrogenase accessory protein HypB
CEW87_13535	ENOG4105F71	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
CEW87_13545	ENOG4105E3S	small subunit
CEW87_13550	ENOG4105DPX	Hydrogenase, large subunit
CEW87_13555	ENOG4105BZU	Histidine kinase
CEW87_13565	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
CEW87_13570	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
CEW87_13575	ENOG4108K5P	(LipO)protein
CEW87_13580	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CEW87_13585	ENOG4105CVE	Lytic murein transglycosylase
CEW87_13590	ENOG4105F8C	transglutaminase domain-containing protein
CEW87_13600	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
CEW87_13610	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CEW87_13615	ENOG4105GJM	(LipO)protein
CEW87_13630	ENOG4105EZE	Cupin 4 family protein
CEW87_13635	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
CEW87_13645	ENOG4105DR4	Methyltransferase
CEW87_13650	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
CEW87_13655	ENOG4105C26	Dehydrogenase
CEW87_13660	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
CEW87_13665	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
CEW87_13670	ENOG4105C3U	ABC transporter
CEW87_13680	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CEW87_13685	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CEW87_13690	ENOG4105DEF	Extracellular solute-binding protein, family 5
CEW87_13695	ENOG4105EVZ	LysR family transcriptional regulator
CEW87_13700	ENOG4108R99	pseudouridine synthase
CEW87_13710	ENOG4105D00	flagellar biosynthetic protein flhB
CEW87_13715	ENOG4105D7B	Flagellar biosynthesis protein flha
CEW87_13720	ENOG4105FZW	flagellar biosynthesis regulator FlhF
CEW87_13730	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CEW87_13735	ENOG4105E14	MotA TolQ exbB proton channel
CEW87_13740	ENOG4105ER2	Ompa motb domain protein
CEW87_13745	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CEW87_13755	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CEW87_13770	ENOG4105CKS	Flagella basal body P-ring formation protein flgA
CEW87_13775	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
CEW87_13780	ENOG4108ZC9	flagellar basal-body rod protein flgc
CEW87_13785	ENOG4105W00	Flagellar hook capping protein
CEW87_13790	ENOG4105BZE	flagellar hook protein, FlgE
CEW87_13795	ENOG4108KPB	Flagellar basal-body rod protein FlgF
CEW87_13800	ENOG4105CGA	flagellar basal-body rod protein FlgG
CEW87_13805	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
CEW87_13810	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
CEW87_13815	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
CEW87_13820	ENOG4105E1Q	flagellar hook-associated protein
CEW87_13825	ENOG4105DTJ	flagellar hook-associated protein
CEW87_13835	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
CEW87_13840	ENOG4105VS8	Flagellar biosynthetic protein fliq
CEW87_13845	ENOG4105CN7	Flagellar biosynthetic protein FliP
CEW87_13855	ENOG4105DD5	Flagellar motor switch protein
CEW87_13860	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
CEW87_13870	ENOG4105WF4	Flagellar hook-length control protein
CEW87_13880	ENOG4105BZU	Histidine kinase
CEW87_13885	ENOG4105BZU	Histidine kinase
CEW87_13895	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
CEW87_13900	ENOG4106PMH	Extracellular solute-binding protein family 3
CEW87_13905	ENOG4105DSP	amino acid AbC transporter
CEW87_13910	ENOG4106YG3	ABC transporter
CEW87_13915	ENOG4108JEH	abc transporter atp-binding protein
CEW87_13940	ENOG4105DXI	Major Facilitator superfamily
CEW87_13950	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
CEW87_13955	ENOG4105C8P	)-transporter
CEW87_13960	ENOG4108I0Y	(ABC) transporter
CEW87_14015	ENOG4105C0D	helicase
CEW87_14065	ENOG4105DFS	Conserved Protein
CEW87_14070	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CEW87_14105	ENOG4105DHT	Metal Dependent Phosphohydrolase
CEW87_14115	ENOG4105BZU	Histidine kinase
CEW87_14120	ENOG4105BZU	Histidine kinase
CEW87_14125	ENOG4105F8J	Adenylate Guanylate cyclase
CEW87_14135	ENOG4105BZU	Histidine kinase
CEW87_14145	ENOG4107ZXU	DSBA oxidoreductase
CEW87_14150	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
CEW87_14155	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
CEW87_14160	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
CEW87_14165	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
CEW87_14175	ENOG4105K4H	Nlp p60 protein
CEW87_14185	ENOG4105FDR	Membrane
CEW87_14190	ENOG4108Z0R	Transferase
CEW87_14210	ENOG4105D94	Major Facilitator Superfamily
CEW87_14215	ENOG4106NZI	LysR family Transcriptional regulator
CEW87_14230	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
CEW87_14235	ENOG4105FDP	GntR family transcriptional regulator
CEW87_14255	ENOG4105E33	succinate dehydrogenase
CEW87_14260	ENOG4105Y75	tpr repeat protein
CEW87_14265	ENOG4105BZN	citrate synthase
CEW87_14270	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
CEW87_14275	ENOG4105C7S	Dehydrogenase
CEW87_14280	ENOG4107QN2	dihydrolipoyl dehydrogenase
CEW87_14285	ENOG4105D6Z	AFG1 family ATPase
CEW87_14310	ENOG4108WWZ	General secretion pathway protein J
CEW87_14325	ENOG4108VAU	general secretion pathway protein G
CEW87_14330	ENOG4105D7Q	type ii secretion system
CEW87_14335	ENOG4107QHF	type ii secretion system protein e
CEW87_14340	ENOG4105GVR	general secretion pathway protein D
CEW87_14355	ENOG4105DVT	helicase
CEW87_14360	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
CEW87_14365	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
CEW87_14370	ENOG4105M00	molybdopterin converting factor, subunit 1
CEW87_14375	ENOG4108ZAF	Molybdopterin
CEW87_14385	ENOG4105E9H	Lytic Murein transglycosylase
CEW87_14400	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
CEW87_14405	ENOG4105D1A	Methyltransferase
CEW87_14410	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CEW87_14415	ENOG4108JDX	DNA polymerase iii, epsilon subunit
CEW87_14420	ENOG4105W87	Cbs domain
CEW87_14435	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
CEW87_14470	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
CEW87_14485	ENOG4108RH0	Crea protein
CEW87_14510	ENOG4105BZU	Histidine kinase
CEW87_14520	ENOG4105C8Q	Methyl-accepting chemotaxis
CEW87_14530	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
CEW87_14540	ENOG4108IJ7	Glycine betaine
CEW87_14545	ENOG4108HQS	Glycine betaine
CEW87_14550	ENOG4105GIJ	Glycine betaine
CEW87_14555	ENOG4105C6T	cysteine synthase
CEW87_14565	ENOG4107QX8	SPFH domain, Band 7 family protein
CEW87_14580	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
CEW87_14590	ENOG4105WH1	Two component transcriptional regulator luxr family
CEW87_14595	ENOG4105BZU	Histidine kinase
CEW87_14610	ENOG4108NWD	Cytochrome
CEW87_14630	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
CEW87_14635	ENOG4105C4M	(Ubiquinol oxidase) subunit I
CEW87_14645	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CEW87_14650	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
CEW87_14670	ENOG4105D3R	alkyl hydroperoxide reductase
CEW87_14680	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
CEW87_14685	ENOG4105DP0	ferredoxin-NADP reductase
CEW87_14695	ENOG4107QSN	dihydrolipoamide acetyltransferase
CEW87_14700	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
CEW87_14705	ENOG4108YXU	transcriptional regulator AsnC family
CEW87_14710	ENOG4107QN2	dihydrolipoyl dehydrogenase
CEW87_14715	ENOG4105C28	cystathionine
CEW87_14720	ENOG4105E5N	succinylglutamate desuccinylase aspartoacylase
CEW87_14725	ENOG4105ENR	peptidase, M24
CEW87_14730	ENOG4105ENR	peptidase, M24
CEW87_14740	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
CEW87_14755	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CEW87_14760	ENOG4108K1J	Transporter DctQ
CEW87_14765	ENOG4108KJ1	Trap dicarboxylate transporter, dctp subunit
CEW87_14780	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
CEW87_14795	ENOG4107QP3	malate synthase g
CEW87_14800	ENOG4105EJ9	Membrane
CEW87_14805	ENOG4105EJC	lysr family transcriptional regulator
CEW87_14825	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
CEW87_14830	ENOG4108Q5Y	Membrane
CEW87_14840	ENOG4105DHG	Allantoate amidinohydrolase
CEW87_14845	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
CEW87_14850	ENOG410633P	Hydantoin racemase
CEW87_14865	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
CEW87_14875	ENOG4105DHG	Allantoate amidinohydrolase
CEW87_14890	ENOG4105VT2	5-hydroxyisourate hydrolase
CEW87_14895	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CEW87_14905	ENOG4107S21	permease
CEW87_14930	ENOG4105DDY	UPF0142 protein ycaO
CEW87_14950	ENOG4108IND	Tetr family transcriptional regulator
CEW87_14970	ENOG4105EN6	Membrane
CEW87_15020	ENOG4105C8Y	Acetylornithine aminotransferase
CEW87_15025	ENOG4105C4W	S-formylglutathione hydrolase
CEW87_15035	ENOG4105CC0	LysR family Transcriptional regulator
CEW87_15055	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
CEW87_15070	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
CEW87_15100	ENOG4105CY0	Metallo-Beta-Lactamase
CEW87_15105	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
CEW87_15115	ENOG4108YY7	Invasion gene expression up-regulator SirB
CEW87_15120	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
CEW87_15125	ENOG4105D4P	Coproporphyrinogen iii oxidase
CEW87_15140	ENOG4105C59	p-type ATPase
CEW87_15150	ENOG4105F0N	pyrophosphate phospho-hydrolase
CEW87_15165	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
CEW87_15170	ENOG4108I6A	alcohol dehydrogenase
CEW87_15175	ENOG4108WUH	Transcriptional regulator, TetR family
CEW87_15190	ENOG4105C4K	Nad synthetase
CEW87_15195	ENOG4108YZA	Nitrogen regulatory protein pii
CEW87_15200	ENOG4108DG9	Smr protein MutS2
CEW87_15205	ENOG4105C3M	thioredoxin reductase
CEW87_15215	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
CEW87_15220	ENOG4105CNU	cell division protein FtsK
CEW87_15225	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
CEW87_15230	ENOG4105D1H	recombination factor protein RarA
CEW87_15240	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
CEW87_15245	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
CEW87_15305	ENOG4105DUM	transcriptional regulator, lysR family
CEW87_15310	ENOG4105HMI	Membrane
CEW87_15320	ENOG4105FDP	GntR family transcriptional regulator
CEW87_15325	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
CEW87_15340	ENOG4108Z4U	Ferredoxin
CEW87_15345	ENOG4106FTQ	Taurine ABC transporter, periplasmic
CEW87_15365	ENOG4105DP0	ferredoxin-NADP reductase
CEW87_15370	ENOG4105BZJ	Electron transfer flavoprotein
CEW87_15375	ENOG4105C10	Electron transfer flavoprotein
CEW87_15385	ENOG4105E90	ABC transporter
CEW87_15390	ENOG4108IJ8	ABC transporter
CEW87_15395	ENOG4108U0I	binding-protein-dependent transport systems inner membrane Component
CEW87_15400	ENOG4107SI7	Substrate-binding region of abc-type glycine betaine transport system
CEW87_15405	ENOG4105C4K	Nad synthetase
CEW87_15410	ENOG4105C1G	acyl-Coa dehydrogenase
CEW87_15415	ENOG4105CEY	Amp-dependent synthetase and ligase
CEW87_15420	ENOG4105E39	Enoyl-CoA hydratase
CEW87_15440	ENOG4108Z18	K06886 hemoglobin
CEW87_15455	ENOG4105CH6	catalase
CEW87_15470	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
CEW87_15475	ENOG4105ETX	regulatoR
CEW87_15480	ENOG4105DHQ	Histidine kinase
CEW87_15495	ENOG4105BZU	Histidine kinase
CEW87_15505	ENOG4105BZU	Histidine kinase
CEW87_15520	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
CEW87_15525	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
CEW87_15540	ENOG4105C58	cytochrome c oxidase accessory protein ccog
CEW87_15545	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
CEW87_15565	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CEW87_15570	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CEW87_15580	ENOG4105F04	LysR family Transcriptional regulator
CEW87_15585	ENOG4105C7F	AcnD-accessory protein PrpF
CEW87_15600	ENOG4108M9J	MaoC like domain protein
CEW87_15605	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
CEW87_15615	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
CEW87_15625	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
CEW87_15630	ENOG41079YP	Citrate utilization protein b
CEW87_15640	ENOG4105C5I	Dehydrogenase
CEW87_15645	ENOG4105C7F	AcnD-accessory protein PrpF
CEW87_15650	ENOG4105JQN	Transcriptional regulator
CEW87_15670	ENOG4105ECR	NmrA family
CEW87_15675	ENOG4105EXG	Transcriptional regulator
CEW87_15690	ENOG4105D9M	gamma-glutamylcysteine synthetase
CEW87_15705	ENOG41086IN	PA14
CEW87_15755	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
CEW87_15790	ENOG4105BZU	Histidine kinase
CEW87_15800	ENOG4105C0H	protease
CEW87_15805	ENOG4105DHQ	Histidine kinase
CEW87_15810	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
CEW87_15830	ENOG4105BZU	Histidine kinase
CEW87_15845	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
CEW87_15860	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CEW87_15875	ENOG4105CJP	fad dependent oxidoreductase
CEW87_15885	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
CEW87_15890	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
CEW87_15900	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
CEW87_15905	ENOG4105HMI	Membrane
CEW87_15915	ENOG4108FUF	Transcriptional regulator, IclR family
CEW87_15945	ENOG4105BZU	Histidine kinase
CEW87_15950	ENOG4108IPJ	Membrane
CEW87_15970	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
CEW87_15975	ENOG4105K3G	Periplasmic Protein
CEW87_15995	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CEW87_16015	ENOG4108FUF	Transcriptional regulator, IclR family
CEW87_16020	ENOG4105P69	integral membrane protein
CEW87_16025	ENOG4108E94	phosphate acetyltransferase
CEW87_16035	ENOG4108FUF	Transcriptional regulator, IclR family
CEW87_16040	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
CEW87_16045	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
CEW87_16055	ENOG4105ETT	transcriptional Regulator, LysR family
CEW87_16060	ENOG4105C1G	acyl-Coa dehydrogenase
CEW87_16065	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
CEW87_16070	ENOG4105BZJ	Electron transfer flavoprotein
CEW87_16075	ENOG4105C10	Electron transfer flavoprotein
CEW87_16080	ENOG4107SUD	Esterase
CEW87_16085	ENOG4108N3W	hemolysin secretion protein
CEW87_16100	ENOG4105E18	UPF0276 protein
CEW87_16125	ENOG4105DXM	phenylacetic acid degradation protein
CEW87_16145	ENOG4108IV0	ABC, transporter
CEW87_16150	ENOG4105C0Z	ABC transporter
CEW87_16160	ENOG4105C32	Amino acid ABC transporter (Permease)
CEW87_16175	ENOG4105MP9	class II Aldolase
CEW87_16180	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
CEW87_16185	ENOG4108IV0	ABC, transporter
CEW87_16190	ENOG4105C0Z	ABC transporter
CEW87_16205	ENOG4105CHR	reductase
CEW87_16210	ENOG4106IPI	cyclase, family
CEW87_16215	ENOG4108IXY	short-chain dehydrogenase reductase
CEW87_16225	ENOG4105CEY	Amp-dependent synthetase and ligase
CEW87_16230	ENOG4108UKV	benzoate 1,2-dioxygenase
CEW87_16260	ENOG4106IPI	cyclase, family
CEW87_16270	ENOG4107TTQ	Alpha beta hydrolase fold
CEW87_16275	ENOG4105MI0	Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively (By similarity)
CEW87_16280	ENOG4105IKQ	hydratase
CEW87_16285	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
CEW87_16290	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
CEW87_16295	ENOG4105CPQ	Dehydrogenase
CEW87_16305	ENOG4108PVQ	transcriptional regulator
CEW87_16320	ENOG4105H37	Glyoxalase Bleomycin resistance protein (Dioxygenase
CEW87_16355	ENOG4107TVJ	,Oxidoreductase FAD NAD(P)-binding
CEW87_16390	ENOG4105CHR	reductase
CEW87_16395	ENOG4108M0I	Transcriptional regulator
CEW87_16430	ENOG4105QAX	Iron-sulfur
CEW87_16435	ENOG4108J2R	molybdopterin oxidoreductase
CEW87_16445	ENOG4105EQP	Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity)
CEW87_16450	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
CEW87_16470	ENOG4105BZU	Histidine kinase
CEW87_16475	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
CEW87_16495	ENOG4108IV0	ABC, transporter
CEW87_16500	ENOG4105C0Z	ABC transporter
CEW87_16505	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
CEW87_16510	ENOG4105C32	Amino acid ABC transporter (Permease)
CEW87_16520	ENOG4108Q89	anthranilate 1,2-dioxygenase large subunit
CEW87_16525	ENOG4108SBK	dioxygenase, subunit beta
CEW87_16535	ENOG4105CHR	reductase
CEW87_16590	ENOG4105C1G	acyl-Coa dehydrogenase
CEW87_16605	ENOG4105E39	Enoyl-CoA hydratase
CEW87_16610	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
CEW87_16615	ENOG4105CHU	acetyl-coa acetyltransferase
CEW87_16620	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CEW87_16635	ENOG4105BZU	Histidine kinase
CEW87_16640	ENOG4108Z6B	deaminase
CEW87_16645	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
CEW87_16650	ENOG41082BV	acetyltransferase
CEW87_16670	ENOG4105HHA	aminodeoxychorismate lyase
CEW87_16675	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
CEW87_16680	ENOG4107QRG	dna polymerase iii
CEW87_16690	ENOG4105F8V	Hydrolase, tatD family
CEW87_16700	ENOG4105D82	Glutamate dehydrogenase
CEW87_16710	ENOG4105DGU	Histone deacetylase
CEW87_16720	ENOG4105NPQ	Pfam:DUF403
CEW87_16730	ENOG4105CH2	amidohydrolase
CEW87_16735	ENOG4105CV6	ABC transporter, permease
CEW87_16745	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CEW87_16755	ENOG4105DAN	ATP-dependent protease
CEW87_16770	ENOG4105HEI	LysR family (Transcriptional regulator
CEW87_16775	ENOG4105F27	Major Facilitator
CEW87_16790	ENOG4105CGF	Aromatic amino acid aminotransferase
CEW87_16795	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
CEW87_16805	ENOG4105C03	ribonuclease
CEW87_16815	ENOG4105EI2	Pseudouridine synthase
CEW87_16820	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
CEW87_16830	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
CEW87_16835	ENOG4108UHJ	MAF-like protein
CEW87_16840	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
CEW87_16845	ENOG4105VGS	50s ribosomal protein l32
CEW87_16850	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
CEW87_16855	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
CEW87_16860	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
CEW87_16865	ENOG4105CHR	reductase
CEW87_16870	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
CEW87_16875	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CEW87_16885	ENOG4108IYU	L-aspartate oxidase
CEW87_16890	ENOG4105EMN	RNA polymerase sigma factor
CEW87_16900	ENOG4105VQK	sigma E regulatory protein, MucB RseB
CEW87_16910	ENOG4105C0H	protease
CEW87_16920	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
CEW87_16925	ENOG4105C3F	Signal peptidase i
CEW87_16935	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
CEW87_16940	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
CEW87_16945	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
CEW87_16950	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
CEW87_16955	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
CEW87_16960	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
CEW87_16965	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
CEW87_17000	ENOG4106T14	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CEW87_17010	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
CEW87_17015	ENOG4107QMS	site-determining protein
CEW87_17020	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
CEW87_17025	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
CEW87_17030	ENOG4105KUZ	arsenate reductase
CEW87_17035	ENOG4105BZM	domain protein
CEW87_17045	ENOG4105CD5	CoA-binding domain protein
CEW87_17050	ENOG4105BZU	Histidine kinase
CEW87_17060	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
CEW87_17065	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
CEW87_17070	ENOG4108UJV	acyl-CoA thioesterase i
CEW87_17075	ENOG4108I0Y	(ABC) transporter
CEW87_17080	ENOG4107S11	squalene-associated FAD-dependent desaturase
CEW87_17095	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CEW87_17110	ENOG4105BZU	Histidine kinase
CEW87_17125	ENOG4105EW9	transcriptional regulator AsnC family
CEW87_17130	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
CEW87_17135	ENOG4105D3G	Pseudouridine synthase
CEW87_17140	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
CEW87_17155	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
CEW87_17165	ENOG41072GX	Peptidase M22 Glycoprotease
CEW87_17175	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CEW87_17180	ENOG4105E0F	Histidine kinase
CEW87_17185	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
CEW87_17195	ENOG4107835	probably involved in intracellular septation (By similarity)
CEW87_17200	ENOG4105K9H	YciI-like protein
CEW87_17205	ENOG4105M85	Bola protein
CEW87_17210	ENOG4107TF3	peptidylprolyl cis-trans isomerase
CEW87_17215	ENOG4105CSU	acyl-Coa dehydrogenase
CEW87_17225	ENOG4105C10	Electron transfer flavoprotein
CEW87_17230	ENOG4105BZJ	Electron transfer flavoprotein
CEW87_17235	ENOG4107Z3H	Transcriptional regulator, TetR family
CEW87_17240	ENOG4105EYA	deoxyribonuclease
CEW87_17245	ENOG4105E39	Enoyl-CoA hydratase
CEW87_17250	ENOG4105CEY	Amp-dependent synthetase and ligase
CEW87_17265	ENOG4105DHJ	ABC, transporter
CEW87_17275	ENOG4105C9X	ppx gppa phosphatase
CEW87_17280	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
CEW87_17285	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
CEW87_17295	ENOG4108IPJ	Membrane
CEW87_17320	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
CEW87_17325	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
CEW87_17335	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
CEW87_17340	ENOG4105NBF	ammecr1 domain protein
CEW87_17360	ENOG4108JA2	transcriptioN-repair coupling factor
CEW87_17365	ENOG4105C08	Histidine kinase
CEW87_17370	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
CEW87_17375	ENOG4105D5K	Hemolysin activator protein
CEW87_17385	ENOG4105D7N	magnesium and cobalt transport protein CorA
CEW87_17395	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
CEW87_17400	ENOG4105EAC	phosphoserine phosphatase
CEW87_17410	ENOG4105D1Q	UPF0246 protein
CEW87_17425	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CEW87_17430	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CEW87_17435	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CEW87_17440	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
CEW87_17445	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CEW87_17455	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CEW87_17460	ENOG4105DZP	Membrane-associated zinc metalloprotease
CEW87_17465	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
CEW87_17470	ENOG4105KNE	Phosphatidate cytidylyltransferase
CEW87_17475	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
CEW87_17480	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
CEW87_17485	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
CEW87_17490	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
CEW87_17495	ENOG4105CE9	30S ribosomal protein S2
CEW87_17500	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
CEW87_17505	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
CEW87_17510	ENOG4108TEB	UPF0114 protein
CEW87_17515	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
CEW87_17525	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
CEW87_17530	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
CEW87_17540	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
CEW87_17545	ENOG4105CHM	Aminotransferase
CEW87_17550	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
CEW87_17555	ENOG4105CZX	twitching motility protein
CEW87_17560	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
CEW87_17575	ENOG4105WVQ	Fe-S assembly protein IscX
CEW87_17580	ENOG4108ZIT	Ferredoxin, 2FE-2S
CEW87_17585	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
CEW87_17590	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
CEW87_17595	ENOG4108Z4V	iron-sulfur cluster assembly
CEW87_17600	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
CEW87_17605	ENOG4105C3J	Cysteine desulfurase
CEW87_17610	ENOG4105C3J	Cysteine desulfurase
CEW87_17615	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
CEW87_17620	ENOG4105D7W	serine acetyltransferase
CEW87_17630	ENOG4105ECY	inositol monophosphatase
CEW87_17635	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CEW87_17700	ENOG4108QJ2	2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase
CEW87_17705	ENOG4105CF7	AraC family transcriptional regulator
CEW87_17745	ENOG4105EKQ	RNA-directed DNA polymerase
CEW87_17750	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
CEW87_17755	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CEW87_17765	ENOG4105VDB	UPF0125 protein
CEW87_17775	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
CEW87_17780	ENOG4105CNG	UPF0061 protein
CEW87_17785	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CEW87_17800	ENOG4105FFC	UPF0187 protein
CEW87_17805	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
CEW87_17810	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
CEW87_17815	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
CEW87_17820	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
CEW87_17825	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CEW87_17840	ENOG4107QZ7	Cellulose synthase catalytic subunit
CEW87_17845	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
CEW87_17850	ENOG4105DUM	transcriptional regulator, lysR family
CEW87_17855	ENOG4105DP0	ferredoxin-NADP reductase
CEW87_17860	ENOG4105CA0	peroxidase
CEW87_17865	ENOG4105BZU	Histidine kinase
CEW87_17870	ENOG4108V06	Glutathione peroxidase
CEW87_17880	ENOG4105C5H	ABC transporter
CEW87_17885	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
CEW87_17935	ENOG4108EC8	DNA internalization-related competence protein ComEC
CEW87_17945	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CEW87_17955	ENOG4105CCT	upf0313 protein
CEW87_17970	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
CEW87_17975	ENOG4105K59	histidine triad (HIT) protein
CEW87_18000	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
CEW87_18020	ENOG4105E5M	Multidrug resistance protein D
CEW87_18025	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CEW87_18060	ENOG4105RD8	TRAP dicarboxylate transporter
CEW87_18065	ENOG4105CEY	Amp-dependent synthetase and ligase
CEW87_18070	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
CEW87_18090	ENOG4105EVZ	LysR family transcriptional regulator
CEW87_18100	ENOG4108HW3	(ABC) transporter
CEW87_18105	ENOG4105E5Q	amino acid AbC transporter
CEW87_18110	ENOG4105E5Q	amino acid AbC transporter
CEW87_18145	ENOG410829K	Lysine exporter protein (Lyse ygga)
CEW87_18160	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
CEW87_18165	ENOG4107RCI	amp-dependent synthetase and ligase
CEW87_18170	ENOG4105CTK	cobaltochelatase, cobn subunit
CEW87_18185	ENOG4105BZU	Histidine kinase
CEW87_18190	ENOG4105BZU	Histidine kinase
CEW87_18260	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
CEW87_18265	ENOG4108R86	Transcriptional regulator
CEW87_18270	ENOG4107TFB	basic membrane
CEW87_18275	ENOG4108JQ9	ABC transporter
CEW87_18290	ENOG4105DZC	cytosine deaminase
CEW87_18295	ENOG4105CGF	Aromatic amino acid aminotransferase
CEW87_18340	ENOG4105CRK	lysyL-tRNA synthetase
CEW87_18395	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
CEW87_18400	ENOG4107RUE	extracellular solute-binding protein family 1
CEW87_18405	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CEW87_18410	ENOG4105F38	ABC transporter, permease
CEW87_18415	ENOG4105D38	putrescine abc transporter
CEW87_18420	ENOG4105BZG	amino acid carrier protein
CEW87_18430	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
CEW87_18445	ENOG4105BZU	Histidine kinase
CEW87_18450	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
CEW87_18465	ENOG4106TD9	Diguanylate cyclase
CEW87_18475	ENOG4105CRQ	synthase (Component I)
CEW87_18485	ENOG4107QJE	Chromosome Partitioning Protein
CEW87_18505	ENOG4105C5I	Dehydrogenase
CEW87_18510	ENOG4105C0B	DNA polymerase III (alpha subunit)
CEW87_18515	ENOG4105FC8	fad dependent oxidoreductase
CEW87_18525	ENOG4105CPQ	Dehydrogenase
CEW87_18545	ENOG4105D6E	homoserine dehydrogenase
CEW87_18550	ENOG4105CHM	Aminotransferase
CEW87_18560	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CEW87_18565	ENOG4108IAB	Phoh family
CEW87_18570	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
CEW87_18585	ENOG4105K4H	Nlp p60 protein
CEW87_18600	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
CEW87_18605	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CEW87_18610	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
CEW87_18615	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
CEW87_18620	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
CEW87_18625	ENOG4105DGN	Electron transport complex
CEW87_18630	ENOG4108R3D	Electron transport complex
CEW87_18645	ENOG4108UQQ	Electron transport complex
CEW87_18655	ENOG4105CSM	endonuclease III
CEW87_18665	ENOG4106RE7	Cytochrome
CEW87_18670	ENOG4106RE7	Cytochrome
CEW87_18675	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CEW87_18695	ENOG4105PX9	Transcriptional regulator, MarR family
CEW87_18700	ENOG4105CMQ	Chloride channel
CEW87_18710	ENOG4105BZU	Histidine kinase
CEW87_18725	ENOG4105C32	Amino acid ABC transporter (Permease)
CEW87_18735	ENOG4108IV0	ABC, transporter
CEW87_18740	ENOG4105C0Z	ABC transporter
CEW87_18745	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
CEW87_18760	ENOG4105EGS	Mechanosensitive ion channel
CEW87_18775	ENOG4105EV9	Alpha Beta Hydrolase
CEW87_18790	ENOG4105PGM	cation diffusion facilitator family transporter
CEW87_18800	ENOG4105DKK	Benzoate
CEW87_18830	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CEW87_18840	ENOG4105BZU	Histidine kinase
CEW87_18860	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
CEW87_18865	ENOG41082UD	thioesterase Superfamily protein
CEW87_18870	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
CEW87_18885	ENOG4107ENK	receptor
CEW87_18895	ENOG4105HEE	Binding Domain protein
CEW87_18905	ENOG4107RNH	Outer membrane receptor FepA
CEW87_18930	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
CEW87_18935	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
CEW87_18945	ENOG4105CKK	Glycosyl transferase, family 2
CEW87_18965	ENOG4105E4C	Lytic transglycosylase catalytic
CEW87_18975	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
CEW87_18985	ENOG4105E0X	reductase
CEW87_18990	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
CEW87_19005	ENOG4108RXX	maleylacetoacetate isomerase
CEW87_19030	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
CEW87_19090	ENOG4105C26	Dehydrogenase
CEW87_19095	ENOG4107QZF	nitrite reductase NADPH large subunit
CEW87_19110	ENOG4108MP6	LysR family Transcriptional regulator
CEW87_19115	ENOG4105C94	Transporter
CEW87_19120	ENOG4105H1N	peptidase, M24
CEW87_19130	ENOG4107QN1	sodium solute
CEW87_19135	ENOG4108IRC	dna polymerase iii
CEW87_19145	ENOG4105BZU	Histidine kinase
CEW87_19155	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
CEW87_19170	ENOG4108VKQ	nitriC oxide reductase
CEW87_19175	ENOG4105DSQ	Nitric oxide reductase
CEW87_19185	ENOG4105C2C	drug resistance transporter, Bcr CflA
CEW87_19200	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
CEW87_19215	ENOG4105FAE	von Willebrand factor, type A
CEW87_19225	ENOG4105EU0	Major facilitator Superfamily
CEW87_19235	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
CEW87_19240	ENOG4105TMB	Formate nitrite transporter
CEW87_19250	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
CEW87_19255	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
CEW87_19260	ENOG4108IPJ	Membrane
CEW87_19265	ENOG4108594	Permease of the drug metabolite transporter
CEW87_19290	ENOG4108UMR	transcriptional regulator AsnC family
CEW87_19300	ENOG4108UMR	transcriptional regulator AsnC family
CEW87_19305	ENOG4106P6N	cytochrome d1 heme region
CEW87_19310	ENOG4105Y7H	Cytochrome
CEW87_19315	ENOG4105F64	nitrite reductase
CEW87_19320	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
CEW87_19325	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
CEW87_19335	ENOG4105C8Q	Methyl-accepting chemotaxis
CEW87_19355	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CEW87_19360	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
CEW87_19365	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
CEW87_19370	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
CEW87_19375	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
CEW87_19380	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
CEW87_19385	ENOG4105CHV	Transcription elongation factor NusA
CEW87_19390	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
CEW87_19395	ENOG4105FE9	pseudouridine synthase
CEW87_19400	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
CEW87_19405	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
CEW87_19410	ENOG4105C31	Tryptophanyl-tRNA synthetase
CEW87_19415	ENOG4108Z4T	Peptidase M50
CEW87_19420	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
CEW87_19425	ENOG4105DB7	PHP domain protein
CEW87_19435	ENOG4105BZU	Histidine kinase
CEW87_19440	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CEW87_19450	ENOG4108YZY	peptidylprolyl cis-trans isomerase
CEW87_19455	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CEW87_19460	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
CEW87_19475	ENOG4105KZX	Pterin carbinolamine dehydratase
CEW87_19485	ENOG4105CBX	hi0933 family
CEW87_19510	ENOG4105FQT	
CEW87_19520	ENOG4105CFP	Peptidase U32
CEW87_19525	ENOG41069P5	Protein slyX homolog
CEW87_19535	ENOG4105FZE	dinitrogenase iron-molybdenum cofactor biosynthesis
CEW87_19550	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
CEW87_19555	ENOG4105VEQ	Cold shock protein
CEW87_19560	ENOG4105C1J	atp-dependent rna helicase
CEW87_19585	ENOG4108VWS	Yaeq family
CEW87_19600	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
CEW87_19610	ENOG4105EUJ	GTP cyclohydrolase i
CEW87_19620	ENOG4105CJ3	phosphate transporter
CEW87_19630	ENOG4105D6S	protein involved in catabolism of external DNA
CEW87_19635	ENOG4105DZ0	fad dependent oxidoreductase
CEW87_19640	ENOG4105C2W	permease
CEW87_19645	ENOG4108VPC	n-acetylmuramoyl-l-alanine amidase
CEW87_19655	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
CEW87_19660	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
CEW87_19670	ENOG4105CQZ	Histidine kinase
CEW87_19690	ENOG4105D5U	fad dependent oxidoreductase
CEW87_19715	ENOG4108R5S	membrane
CEW87_19720	ENOG4105C58	cytochrome c oxidase accessory protein ccog
CEW87_19725	ENOG4105KPV	Transcriptional regulator
CEW87_19730	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CEW87_19735	ENOG4105CKW	Inner membrane protein yedI
CEW87_19755	ENOG4105MSY	salicylate hydroxylase
CEW87_19765	ENOG4105RD8	TRAP dicarboxylate transporter
CEW87_19775	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CEW87_19785	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
CEW87_19795	ENOG4105DER	m42 family
CEW87_19800	ENOG4107RRY	Cyanophycin synthetase
CEW87_19835	ENOG4105EXG	Transcriptional regulator
CEW87_19840	ENOG4105EUB	pirin domain protein
CEW87_19845	ENOG4108Z66	YbaK ebsC protein
CEW87_19850	ENOG4105C5W	Aldolase
CEW87_19855	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
CEW87_19860	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
CEW87_19870	ENOG4105DFF	Rod shape-determining protein mreb
CEW87_19880	ENOG4105CIN	aminoacyl-histidine dipeptidase
CEW87_19900	ENOG4105E3J	oxidoreductase
CEW87_19920	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
CEW87_19925	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
CEW87_19935	ENOG4107T8V	it plays a direct role in the translocation of protons across the membrane (By similarity)
CEW87_19945	ENOG4108Q71	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
CEW87_19950	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
CEW87_19960	ENOG4105BZ1	(ABC) transporter
CEW87_19970	ENOG4105EEQ	Na H antiporter
CEW87_19975	ENOG4105EQ0	Major Facilitator superfamily
CEW87_19985	ENOG4105C5I	Dehydrogenase
CEW87_19990	ENOG4108UT2	hemolysin iii
CEW87_20000	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
CEW87_20005	ENOG4105K63	Thioredoxin
CEW87_20010	ENOG4105CSU	acyl-Coa dehydrogenase
CEW87_20025	ENOG4105CHU	acetyl-coa acetyltransferase
CEW87_20030	ENOG4105E9F	Enoyl-CoA hydratase
CEW87_20035	ENOG4105CEY	Amp-dependent synthetase and ligase
CEW87_20045	ENOG4108IV0	ABC, transporter
CEW87_20050	ENOG4105C0Z	ABC transporter
CEW87_20065	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CEW87_20075	ENOG4105CH5	extracellular solute-binding protein, family 7
CEW87_20100	ENOG4105CPC	Aldo Keto reductase
CEW87_20120	ENOG4105GAK	amidohydrolase 2
CEW87_20130	ENOG4105KHM	amidohydrolase 2
CEW87_20150	ENOG4107QJN	gtp cyclohydrolase ii
CEW87_20165	ENOG4105BZU	Histidine kinase
CEW87_20175	ENOG4105BZU	Histidine kinase
CEW87_20215	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
CEW87_20220	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
CEW87_20225	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
CEW87_20230	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
CEW87_20235	ENOG4105CYN	Serine protein kinase
CEW87_20240	ENOG4106AKX	UPF0229 protein
CEW87_20245	ENOG4105ED1	spovr family
CEW87_20250	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
CEW87_20260	ENOG4107Y9U	Membrane
CEW87_20265	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
CEW87_20270	ENOG4108WQI	RNA Polymerase
CEW87_20280	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
CEW87_20310	ENOG4105E2K	Glycosyl transferase (Group 1
CEW87_20325	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
CEW87_20335	ENOG4105N1F	Hnh endonuclease
CEW87_20340	ENOG4105WKW	Pfam:DUF1458
CEW87_20375	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CEW87_20385	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
CEW87_20395	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CEW87_20400	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
CEW87_20405	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
CEW87_20410	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
CEW87_20415	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
CEW87_20420	ENOG4108ZXC	Two component transcriptional regulator, luxr family
CEW87_20425	ENOG4105BZU	Histidine kinase
CEW87_20435	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
CEW87_20440	ENOG4107QSN	dihydrolipoamide acetyltransferase
CEW87_20445	ENOG4107QN2	dihydrolipoyl dehydrogenase
CEW87_20475	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
CEW87_20480	ENOG4105K8N	protein family UPF0079, ATPase
CEW87_20485	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
CEW87_20490	ENOG4105DTN	riboflavin biosynthesis protein ribF
CEW87_20495	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
CEW87_20500	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
CEW87_20505	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
CEW87_20510	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
CEW87_20520	ENOG41082UU	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CEW87_20530	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
CEW87_20535	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
CEW87_20540	ENOG4105DEN	Luciferase family
CEW87_20550	ENOG4105CPP	Dehydrogenase, E1 component
CEW87_20555	ENOG4107RUY	(E1 component), alpha subunit
CEW87_20570	ENOG4107QIJ	Aconitate hydratase 2
CEW87_20575	ENOG4107QM5	aconitate hydratase
CEW87_20580	ENOG4105K5B	UPF0225 protein
CEW87_20615	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
CEW87_20620	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
CEW87_20625	ENOG4105VFB	Binds the 23S rRNA (By similarity)
CEW87_20635	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
CEW87_20640	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
CEW87_20665	ENOG4105CHU	acetyl-coa acetyltransferase
CEW87_20695	ENOG4108VPT	UPF0234 protein
CEW87_20700	ENOG4105NBK	UPF0345 protein
CEW87_20710	ENOG4105CDH	Citrulline--aspartate ligase
CEW87_20715	ENOG4105DBV	ornithine carbamoyltransferase
CEW87_20720	ENOG4105C8Y	Acetylornithine aminotransferase
CEW87_20730	ENOG41082GY	Binds directly to 16S ribosomal RNA (By similarity)
CEW87_20735	ENOG4105CJR	Integral membrane protein (MviN
CEW87_20740	ENOG4108V1U	phospholipid-binding protein
CEW87_20755	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
CEW87_20760	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
CEW87_20765	ENOG4105W49	UPF0434 protein
CEW87_20770	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
CEW87_20785	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CEW87_20790	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
CEW87_20795	ENOG4105DR9	pseudouridine synthase
CEW87_20805	ENOG4105CBS	Chea signal transduction histidine kinase
CEW87_20810	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
CEW87_20815	ENOG4108VYJ	response regulator receiver protein
CEW87_20820	ENOG4107R88	Chemotaxis protein (CheV)
CEW87_20825	ENOG4107R88	Chemotaxis protein (CheV)
CEW87_20830	ENOG4108N3W	hemolysin secretion protein
CEW87_20835	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
CEW87_20840	ENOG4105BZU	Histidine kinase
CEW87_20845	ENOG4105ER2	Ompa motb domain protein
CEW87_20850	ENOG4107RD7	Flagellar Motor Protein, MotA
CEW87_20855	ENOG4106CIA	Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region
CEW87_20860	ENOG4105GEH	Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity)
CEW87_20865	ENOG4105BZU	Histidine kinase
CEW87_20895	ENOG4108JQ9	ABC transporter
CEW87_20900	ENOG4105UIB	(ABC) transporter
CEW87_20955	ENOG4108YRB	methyltransferase
CEW87_20960	ENOG4105CTC	Lipopolysaccharide biosynthesis protein-like protein
CEW87_20970	ENOG4105I03	Flagellin
CEW87_20980	ENOG4105DTS	flagellar hook-associated
CEW87_20985	ENOG4105MQ3	flagellar protein FliS
CEW87_21000	ENOG4105VM1	flagellar
CEW87_21005	ENOG4108T7K	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity)
CEW87_21010	ENOG4108T7K	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity)
CEW87_21015	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
CEW87_21020	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
CEW87_21025	ENOG4105W8H	transhydrogenase (subunit alpha
CEW87_21030	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
CEW87_21035	ENOG4105DG4	malate L-lactate dehydrogenase
CEW87_21040	ENOG4108JQ1	Dehydrogenase
CEW87_21060	ENOG4105CTX	dehydratase
CEW87_21065	ENOG4105VP7	SAF domain protein
CEW87_21070	ENOG4105FDP	GntR family transcriptional regulator
CEW87_21075	ENOG4105FDP	GntR family transcriptional regulator
CEW87_21080	ENOG4105HMI	Membrane
CEW87_21085	ENOG4105ECY	inositol monophosphatase
CEW87_21090	ENOG4105ETE	Transcriptional regulator (LacI family
CEW87_21100	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
CEW87_21110	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CEW87_21120	ENOG4105CHR	reductase
CEW87_21130	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
CEW87_21140	ENOG4105BZU	Histidine kinase
CEW87_21145	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
CEW87_21150	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
CEW87_21160	ENOG4108JIR	Flagellum-specific ATP synthase
CEW87_21170	ENOG4107QUY	Guanine deaminase
CEW87_21175	ENOG4108W2P	Methyl-accepting chemotaxis
CEW87_21185	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
CEW87_21190	ENOG4105C11	sulfate adenylyltransferase), subunit 2
CEW87_21200	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
CEW87_21205	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
CEW87_21210	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
CEW87_21215	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
CEW87_21225	ENOG4105ETT	transcriptional Regulator, LysR family
CEW87_21240	ENOG4105CY0	Metallo-Beta-Lactamase
CEW87_21260	ENOG4107ZF2	Phosphatase
CEW87_21275	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
CEW87_21280	ENOG4105C2X	Arabinose 5-phosphate isomerase
CEW87_21285	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
CEW87_21295	ENOG4105EVB	acetyltransferase
CEW87_21320	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
CEW87_21330	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
CEW87_21335	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
CEW87_21345	ENOG4105DAY	polysaccharide export protein
CEW87_21355	ENOG4105D3Q	Sugar transferase
CEW87_21360	ENOG4105BZU	Histidine kinase
CEW87_21365	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CEW87_21380	ENOG4105CPI	Metal Dependent Phosphohydrolase
CEW87_21390	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
CEW87_21425	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CEW87_21450	ENOG4108JB9	formate dehydrogenase
CEW87_21505	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CEW87_21515	ENOG4109045	doxx family
CEW87_21525	ENOG4105E18	UPF0276 protein
CEW87_21550	ENOG4105CN1	protease
CEW87_21570	ENOG4105CFH	Aspartokinase
CEW87_21585	ENOG4107XVI	synthase
CEW87_21595	ENOG4105EGS	Mechanosensitive ion channel
CEW87_21600	ENOG4105N82	Endonuclease
CEW87_21615	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
CEW87_21625	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
CEW87_21630	ENOG4108UM1	dedA family
CEW87_21640	ENOG4105BZU	Histidine kinase
CEW87_21655	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
CEW87_21685	ENOG4105C7K	acetolactate synthase
CEW87_21690	ENOG4108ZP8	Acetolactate synthase small subunit
CEW87_21695	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
CEW87_21710	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
CEW87_21725	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
CEW87_21740	ENOG4105DHQ	Histidine kinase
CEW87_21750	ENOG4105FQR	PH-inducible protein involved in stress response
CEW87_21760	ENOG4105IFJ	Histidine kinase
CEW87_21765	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
CEW87_21775	ENOG4105VBA	Cytochrome
CEW87_21785	ENOG4105E3J	oxidoreductase
CEW87_21790	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
CEW87_21800	ENOG4105CS1	NAD(P)H quinone oxidoreductase
CEW87_21805	ENOG4107S2Z	UPF0761 membrane protein
CEW87_21815	ENOG4105K5M	30s ribosomal protein S16
CEW87_21820	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
CEW87_21825	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
CEW87_21830	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
CEW87_21840	ENOG4108M8S	permease YjgP YjgQ family protein
CEW87_21845	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
CEW87_21860	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CEW87_21870	ENOG4105CH5	extracellular solute-binding protein, family 7
CEW87_21875	ENOG4105CR8	Transcriptional regulator
CEW87_21880	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
CEW87_21885	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
CEW87_21890	ENOG4105ERG	peptidase m48, ste24p
CEW87_21895	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CEW87_21925	ENOG4107S1Q	Phosphatase
CEW87_21950	ENOG4108T5I	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
CEW87_21975	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
CEW87_21985	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
CEW87_22005	ENOG4105DS1	cytochrome b561
CEW87_22010	ENOG4105W2Z	cytochrome C, class I
CEW87_22020	ENOG4105C26	Dehydrogenase
CEW87_22025	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
CEW87_22040	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CEW87_22045	ENOG4105CQZ	Histidine kinase
CEW87_22050	ENOG4105CEY	Amp-dependent synthetase and ligase
CEW87_22055	ENOG4105CSU	acyl-Coa dehydrogenase
CEW87_22060	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
CEW87_22075	ENOG4105C72	UPF0176 protein
CEW87_22085	ENOG4108JQ6	ABC transporter
CEW87_22090	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CEW87_22095	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CEW87_22100	ENOG4105DEF	Extracellular solute-binding protein, family 5
CEW87_22110	ENOG4105DND	Transcriptional regulator
CEW87_22130	ENOG4105EGS	Mechanosensitive ion channel
CEW87_22155	ENOG4108F3G	Type I restriction-modification system, R subunit
CEW87_22170	ENOG4107QTH	restriction modification system DNA specificity domain
CEW87_22195	ENOG4108YZN	class I peptide chain release factor
CEW87_22220	ENOG4105UTB	Blue (Type 1) copper domain protein