locus-tag	class	description
CEW83_00005	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CEW83_00010	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CEW83_00015	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CEW83_00020	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CEW83_00025	COG0573	inorganic phosphate transmembrane transporter activity
CEW83_00030	COG0581	inorganic phosphate transmembrane transporter activity
CEW83_00035	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CEW83_00045	COG0149	triose-phosphate isomerase activity
CEW83_00060	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CEW83_00065	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CEW83_00070	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CEW83_00075	COG0649	NAD binding
CEW83_00080	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CEW83_00085	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CEW83_00090	COG1034	ATP synthesis coupled electron transport
CEW83_00095	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CEW83_00100	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CEW83_00110	COG0713	ATP synthesis coupled electron transport
CEW83_00125	COG1007	ATP synthesis coupled electron transport
CEW83_00150	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CEW83_00155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEW83_00160	COG1129	ABC transporter
CEW83_00160	COG0842	Transport permease protein
CEW83_00165	COG0842	Transport permease protein
CEW83_00170	COG1309	transcriptional regulator
CEW83_00185	COG0330	HflC and HflK could
CEW83_00195	COG1126	abc transporter atp-binding protein
CEW83_00200	COG0765	amino acid transport
CEW83_00205	COG0765	amino acid transport
CEW83_00220	COG2200	EAL domain
CEW83_00225	COG1522	sequence-specific DNA binding
CEW83_00235	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CEW83_00240	COG0583	DNA-binding transcription factor activity
CEW83_00245	COG1304	FMN binding
CEW83_00255	COG0564	pseudouridine synthase activity
CEW83_00270	COG3243	poly(R)-hydroxyalkanoic acid synthase
CEW83_00275	COG1028	Short-chain dehydrogenase reductase Sdr
CEW83_00285	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
CEW83_00290	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CEW83_00295	COG1752	Esterase of the alpha-beta hydrolase superfamily
CEW83_00300	COG0277	FAD linked oxidase domain protein
CEW83_00340	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
CEW83_00345	COG1250	3-hydroxyacyl-CoA dehydrogenase
CEW83_00350	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CEW83_00360	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CEW83_00370	COG0318	PFAM AMP-dependent synthetase and ligase
CEW83_00375	COG0028	Belongs to the TPP enzyme family
CEW83_00380	COG0440	acetolactate synthase activity
CEW83_00385	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CEW83_00395	COG4783	chaperone-mediated protein folding
CEW83_00400	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CEW83_00405	COG0066	3-isopropylmalate dehydratase activity
CEW83_00410	COG0473	3-isopropylmalate dehydrogenase activity
CEW83_00430	COG0101	tRNA pseudouridine synthase activity
CEW83_00435	COG0135	phosphoribosylanthranilate isomerase activity
CEW83_00440	COG0133	tryptophan synthase activity
CEW83_00445	COG0159	tryptophan synthase activity
CEW83_00450	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CEW83_00455	COG0285	dihydrofolate synthase activity
CEW83_00480	COG2239	Acts as a magnesium transporter
CEW83_00490	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEW83_00495	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CEW83_00500	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CEW83_00505	COG0215	cysteine-tRNA ligase activity
CEW83_00515	COG0484	heat shock protein binding
CEW83_00520	COG0443	Heat shock 70 kDa protein
CEW83_00525	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CEW83_00535	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CEW83_00545	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CEW83_00550	COG0287	Prephenate dehydrogenase
CEW83_00555	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CEW83_00565	COG0776	regulation of translation
CEW83_00575	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CEW83_00615	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CEW83_00620	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CEW83_00625	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CEW83_00630	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CEW83_00635	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CEW83_00640	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEW83_00640	COG0072	phenylalanine-tRNA ligase activity
CEW83_00645	COG0776	regulation of translation
CEW83_00665	COG0494	nUDIX hydrolase
CEW83_00675	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CEW83_00680	COG1760	l-serine dehydratase
CEW83_00685	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CEW83_00690	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CEW83_00720	COG1773	rubredoxin
CEW83_00740	COG0375	protein maturation
CEW83_00750	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CEW83_00755	COG0298	carbon dioxide binding
CEW83_00760	COG0409	Hydrogenase expression formation protein
CEW83_00765	COG0309	Hydrogenase expression formation protein (HypE)
CEW83_00770	COG1024	Enoyl-CoA hydratase
CEW83_00770	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CEW83_00775	COG2204	response regulator
CEW83_00780	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CEW83_00790	COG3852	Histidine kinase
CEW83_00800	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CEW83_00805	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CEW83_00820	COG2951	lytic endotransglycosylase activity
CEW83_00835	COG0714	Associated with various cellular activities
CEW83_00840	COG0123	including yeast histone deacetylase and acetoin utilization protein
CEW83_00845	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CEW83_00850	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CEW83_00865	COG2850	peptidyl-arginine hydroxylation
CEW83_00870	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CEW83_00880	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CEW83_00900	COG0154	amidase activity
CEW83_00905	COG0444	Belongs to the ABC transporter superfamily
CEW83_00910	COG4608	Belongs to the ABC transporter superfamily
CEW83_00915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CEW83_00920	COG0601	transmembrane transport
CEW83_00925	COG0747	negative chemotaxis
CEW83_00950	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CEW83_00965	COG1191	sigma factor activity
CEW83_00970	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CEW83_00975	COG1360	Flagellar Motor Protein
CEW83_00995	COG3706	GGDEF domain
CEW83_01000	COG0187	DNA topoisomerase II activity
CEW83_01020	COG1815	bacterial-type flagellum-dependent cell motility
CEW83_01025	COG1558	bacterial-type flagellum-dependent cell motility
CEW83_01030	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CEW83_01035	COG1749	Flagellar hook protein flgE
CEW83_01040	COG4787	bacterial-type flagellum-dependent cell motility
CEW83_01045	COG4786	Flagellar basal body rod
CEW83_01050	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CEW83_01055	COG1706	bacterial-type flagellum-dependent cell motility
CEW83_01060	COG3951	Flagellar rod assembly protein muramidase FlgJ
CEW83_01060	COG1705	Flagellar rod assembly protein muramidase FlgJ
CEW83_01065	COG1256	bacterial-type flagellum assembly
CEW83_01085	COG1987	bacterial-type flagellum assembly
CEW83_01100	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CEW83_01115	COG3144	bacterial-type flagellum assembly
CEW83_01125	COG0745	RESPONSE REGULATOR receiver
CEW83_01125	COG3706	GGDEF domain
CEW83_01130	COG3706	GGDEF domain
CEW83_01145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEW83_01150	COG4215	(ABC) transporter
CEW83_01155	COG4160	amino acid transport
CEW83_01185	COG2814	Major facilitator Superfamily
CEW83_01195	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CEW83_01200	COG0471	metal ion transport
CEW83_01205	COG4181	ATPase activity
CEW83_01240	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CEW83_01265	COG3706	GGDEF domain
CEW83_01265	COG4251	negative regulation of phosphorylation
CEW83_01265	COG5001	Diguanylate cyclase
CEW83_01265	COG2203	Gaf domain
CEW83_01275	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CEW83_01280	COG0504	CTP synthase activity
CEW83_01285	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CEW83_01290	COG0148	phosphopyruvate hydratase activity
CEW83_01295	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CEW83_01305	COG0791	NLP P60 protein
CEW83_01315	COG0697	spore germination
CEW83_01330	COG2814	Major facilitator Superfamily
CEW83_01335	COG0583	DNA-binding transcription factor activity
CEW83_01350	COG0039	L-malate dehydrogenase activity
CEW83_01370	COG1053	succinate dehydrogenase
CEW83_01375	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CEW83_01380	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CEW83_01385	COG0372	Belongs to the citrate synthase family
CEW83_01390	COG0567	Dehydrogenase, E1 component
CEW83_01395	COG0508	dehydrogenase complex catalyzes the overall conversion of
CEW83_01400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEW83_01405	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CEW83_01475	COG1199	ATP-dependent helicase activity
CEW83_01480	COG1763	Mo-molybdopterin cofactor biosynthetic process
CEW83_01485	COG0303	'Molybdopterin
CEW83_01490	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CEW83_01495	COG0314	molybdopterin synthase activity
CEW83_01505	COG0741	lytic transglycosylase activity
CEW83_01505	COG1388	LysM domain
CEW83_01510	COG4251	negative regulation of phosphorylation
CEW83_01510	COG3706	GGDEF domain
CEW83_01510	COG5001	Diguanylate cyclase
CEW83_01510	COG2203	Gaf domain
CEW83_01520	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CEW83_01525	COG2226	methyltransferase
CEW83_01530	COG0328	RNA-DNA hybrid ribonuclease activity
CEW83_01535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CEW83_01540	COG0517	IMP dehydrogenase activity
CEW83_01555	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CEW83_01605	COG3045	CreA protein
CEW83_01640	COG0840	transmembrane signaling receptor activity
CEW83_01650	COG2032	superoxide dismutase activity
CEW83_01665	COG4176	ABC-type proline glycine betaine transport system permease component
CEW83_01670	COG2113	Glycine betaine
CEW83_01675	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CEW83_01685	COG0330	HflC and HflK could
CEW83_01700	COG0446	pyridine nucleotide-disulphide oxidoreductase
CEW83_01705	COG2197	response regulator
CEW83_01735	COG3790	cyd operon protein YbgE
CEW83_01745	COG1294	oxidase, subunit
CEW83_01765	COG0723	plastoquinol--plastocyanin reductase activity
CEW83_01785	COG0450	alkyl hydroperoxide reductase
CEW83_01795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CEW83_01810	COG0508	dehydrogenase complex catalyzes the overall conversion of
CEW83_01820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEW83_01830	COG3608	succinylglutamate desuccinylase aspartoacylase
CEW83_01835	COG0006	proline dipeptidase activity
CEW83_01840	COG0006	proline dipeptidase activity
CEW83_01845	COG2423	ornithine cyclodeaminase activity
CEW83_01850	COG2186	Transcriptional regulator
CEW83_01855	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CEW83_01865	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CEW83_01870	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CEW83_01875	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CEW83_01890	COG2989	Protein conserved in bacteria
CEW83_01905	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CEW83_01910	COG0730	response to heat
CEW83_01915	COG0583	DNA-binding transcription factor activity
CEW83_01935	COG3622	Belongs to the hyi family
CEW83_01940	COG0697	spore germination
CEW83_01945	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CEW83_01950	COG4266	Belongs to the allantoicase family
CEW83_01975	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CEW83_01980	COG4266	Belongs to the allantoicase family
CEW83_01995	COG2351	hydroxyisourate hydrolase activity
CEW83_02030	COG1309	transcriptional regulator
CEW83_02050	COG2860	membrane
CEW83_02090	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CEW83_02100	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CEW83_02105	COG0583	DNA-binding transcription factor activity
CEW83_02115	COG2217	Heavy metal translocating P-type atpase
CEW83_02125	COG3278	Belongs to the heme-copper respiratory oxidase family
CEW83_02170	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CEW83_02175	COG3243	poly(R)-hydroxyalkanoic acid synthase
CEW83_02180	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEW83_02185	COG3094	Invasion gene expression up-regulator, SirB
CEW83_02190	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEW83_02195	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CEW83_02210	COG2217	Heavy metal translocating P-type atpase
CEW83_02220	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CEW83_02235	COG2130	NADP-dependent
CEW83_02240	COG1979	alcohol dehydrogenase
CEW83_02245	COG1309	transcriptional regulator
CEW83_02260	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CEW83_02260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CEW83_02265	COG0347	Belongs to the P(II) protein family
CEW83_02270	COG2840	Smr protein MutS2
CEW83_02275	COG0492	ferredoxin-NADP+ reductase activity
CEW83_02285	COG1674	ftsk spoiiie
CEW83_02290	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CEW83_02295	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CEW83_02305	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CEW83_02310	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CEW83_02340	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CEW83_02355	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CEW83_02380	COG0318	PFAM AMP-dependent synthetase and ligase
CEW83_02440	COG3383	formate dehydrogenase (NAD+) activity
CEW83_02450	COG1960	acyl-CoA dehydrogenase activity
CEW83_02455	COG1960	acyl-CoA dehydrogenase activity
CEW83_02460	COG1024	Enoyl-CoA hydratase
CEW83_02470	COG0302	gtp cyclohydrolase
CEW83_02495	COG0583	DNA-binding transcription factor activity
CEW83_02505	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CEW83_02570	COG1028	Short-chain dehydrogenase reductase Sdr
CEW83_02575	COG0179	Fumarylacetoacetate (FAA) hydrolase
CEW83_02630	COG0179	Fumarylacetoacetate (FAA) hydrolase
CEW83_02635	COG1250	3-hydroxyacyl-CoA dehydrogenase
CEW83_02640	COG0183	Belongs to the thiolase family
CEW83_02675	COG1024	Enoyl-CoA hydratase
CEW83_02680	COG1028	Short-chain dehydrogenase reductase Sdr
CEW83_02700	COG2814	Major facilitator Superfamily
CEW83_02720	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CEW83_02725	COG4638	Rieske (2fe-2S)
CEW83_02730	COG1028	Short-chain dehydrogenase reductase Sdr
CEW83_02755	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CEW83_02770	COG2084	Dehydrogenase
CEW83_02775	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CEW83_02780	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CEW83_02785	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CEW83_02790	COG1028	Short-chain dehydrogenase reductase Sdr
CEW83_02795	COG3958	Transketolase
CEW83_02800	COG3959	Transketolase, thiamine diphosphate binding domain
CEW83_02805	COG0583	DNA-binding transcription factor activity
CEW83_02825	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CEW83_02835	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CEW83_02845	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CEW83_02870	COG2346	COG2346, Truncated hemoglobins
CEW83_02880	COG0167	dihydroorotate dehydrogenase activity
CEW83_02890	COG1418	mRNA catabolic process
CEW83_02895	COG0348	domain, Protein
CEW83_02900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEW83_02920	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CEW83_02925	COG0066	3-isopropylmalate dehydratase activity
CEW83_02935	COG0583	DNA-binding transcription factor activity
CEW83_02940	COG2828	Protein conserved in bacteria
CEW83_02955	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CEW83_02960	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CEW83_02995	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CEW83_03000	COG2828	Protein conserved in bacteria
CEW83_03010	COG0702	epimerase
CEW83_03030	COG2918	glutathione biosynthetic process
CEW83_03095	COG1222	aaa ATPase
CEW83_03135	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CEW83_03140	COG0642	Histidine kinase
CEW83_03145	COG0745	RESPONSE REGULATOR receiver
CEW83_03160	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CEW83_03190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CEW83_03200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEW83_03205	COG2022	thiamine diphosphate biosynthetic process
CEW83_03215	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CEW83_03220	COG2855	membrane
CEW83_03230	COG1414	Transcriptional regulator
CEW83_03290	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CEW83_03295	COG2823	Periplasmic or secreted lipoprotein
CEW83_03340	COG1414	Transcriptional regulator
CEW83_03345	COG0730	response to heat
CEW83_03360	COG1414	Transcriptional regulator
CEW83_03365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CEW83_03370	COG0242	peptide deformylase activity
CEW83_03380	COG0583	DNA-binding transcription factor activity
CEW83_03385	COG1960	acyl-CoA dehydrogenase activity
CEW83_03390	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CEW83_03405	COG0840	transmembrane signaling receptor activity
CEW83_03420	COG3220	belongs to the UPF0276 family
CEW83_03470	COG0411	ABC transporter
CEW83_03500	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CEW83_03510	COG0411	ABC transporter
CEW83_03525	COG1028	Short-chain dehydrogenase reductase Sdr
CEW83_03530	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CEW83_03535	COG0300	oxidoreductase activity
CEW83_03545	COG0318	PFAM AMP-dependent synthetase and ligase
CEW83_03550	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CEW83_03580	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CEW83_03590	COG0596	Alpha beta hydrolase
CEW83_03590	COG0508	dehydrogenase complex catalyzes the overall conversion of
CEW83_03595	COG3384	dioxygenase
CEW83_03600	COG3971	2-oxopent-4-enoate hydratase activity
CEW83_03605	COG4569	acetaldehyde dehydrogenase (acetylating) activity
CEW83_03610	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CEW83_03615	COG1063	alcohol dehydrogenase
CEW83_03625	COG1802	Transcriptional regulator
CEW83_03640	COG0346	lactoylglutathione lyase activity
CEW83_03665	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CEW83_03675	COG0633	Ferredoxin
CEW83_03675	COG0543	2 iron, 2 sulfur cluster binding
CEW83_03715	COG0583	DNA-binding transcription factor activity
CEW83_03745	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CEW83_03750	COG3300	MHYT domain
CEW83_03750	COG5001	Diguanylate cyclase
CEW83_03760	COG0437	4 iron, 4 sulfur cluster binding
CEW83_03775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CEW83_03805	COG0840	transmembrane signaling receptor activity
CEW83_03815	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CEW83_03855	COG1024	Enoyl-CoA hydratase
CEW83_03860	COG1960	acyl-CoA dehydrogenase activity
CEW83_03865	COG1960	acyl-CoA dehydrogenase activity
CEW83_03880	COG1024	Enoyl-CoA hydratase
CEW83_03885	COG1250	3-hydroxyacyl-CoA dehydrogenase
CEW83_03895	COG0516	GMP reductase activity
CEW83_03915	COG0590	tRNA wobble adenosine to inosine editing
CEW83_03920	COG1376	ErfK ybiS ycfS ynhG family protein
CEW83_03925	COG2153	protein acetylation
CEW83_03940	COG0354	folic acid binding
CEW83_03945	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CEW83_03950	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CEW83_03965	COG0084	hydrolase, TatD family'
CEW83_03975	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CEW83_03985	COG0123	including yeast histone deacetylase and acetoin utilization protein
CEW83_03995	COG2308	Evidence 4 Homologs of previously reported genes of
CEW83_03995	COG2307	Protein conserved in bacteria
CEW83_04005	COG1473	amidohydrolase
CEW83_04010	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CEW83_04020	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CEW83_04030	COG1067	ATP-dependent peptidase activity
CEW83_04060	COG0556	nucleotide-excision repair
CEW83_04065	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CEW83_04070	COG1530	ribonuclease E activity
CEW83_04080	COG0564	pseudouridine synthase activity
CEW83_04085	COG0546	phosphoglycolate phosphatase activity
CEW83_04095	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CEW83_04100	COG0424	maF-like protein
CEW83_04105	COG1399	metal-binding, possibly nucleic acid-binding protein
CEW83_04110	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CEW83_04115	COG0416	fatty acid biosynthetic process
CEW83_04120	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CEW83_04125	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CEW83_04135	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEW83_04140	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CEW83_04150	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CEW83_04175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CEW83_04185	COG0481	GTPase activity
CEW83_04190	COG0681	Belongs to the peptidase S26 family
CEW83_04200	COG0571	ribonuclease III activity
CEW83_04205	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CEW83_04210	COG1381	Involved in DNA repair and RecF pathway recombination
CEW83_04215	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CEW83_04220	COG0736	holo-[acyl-carrier-protein] synthase activity
CEW83_04225	COG1472	Belongs to the glycosyl hydrolase 3 family
CEW83_04230	COG0322	excinuclease ABC activity
CEW83_04235	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CEW83_04265	COG0484	heat shock protein binding
CEW83_04275	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CEW83_04285	COG0850	regulation of cytokinetic process
CEW83_04290	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CEW83_04295	COG1393	Belongs to the ArsC family
CEW83_04300	COG2183	response to ionizing radiation
CEW83_04310	COG0045	succinate-CoA ligase (ADP-forming) activity
CEW83_04310	COG1042	CoA-binding domain protein
CEW83_04310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEW83_04315	COG2202	Pas domain
CEW83_04315	COG2205	protein histidine kinase activity
CEW83_04325	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CEW83_04330	COG0709	Synthesizes selenophosphate from selenide and ATP
CEW83_04340	COG4181	ATPase activity
CEW83_04345	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CEW83_04350	COG1562	ergosterol biosynthetic process
CEW83_04355	COG1562	ergosterol biosynthetic process
CEW83_04375	COG5001	Diguanylate cyclase
CEW83_04375	COG5002	protein histidine kinase activity
CEW83_04395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CEW83_04400	COG0564	pseudouridine synthase activity
CEW83_04410	COG0583	DNA-binding transcription factor activity
CEW83_04420	COG1573	uracil-dna glycosylase
CEW83_04440	COG0745	RESPONSE REGULATOR receiver
CEW83_04445	COG2205	protein histidine kinase activity
CEW83_04450	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CEW83_04460	COG2917	probably involved in intracellular septation
CEW83_04465	COG2350	Protein conserved in bacteria
CEW83_04470	COG0271	Belongs to the BolA IbaG family
CEW83_04475	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CEW83_04480	COG1960	acyl-CoA dehydrogenase activity
CEW83_04500	COG1309	transcriptional regulator
CEW83_04505	COG0084	hydrolase, TatD family'
CEW83_04510	COG1024	Enoyl-CoA hydratase
CEW83_04515	COG0318	PFAM AMP-dependent synthetase and ligase
CEW83_04530	COG1127	ABC transporter
CEW83_04535	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CEW83_04540	COG0248	Ppx GppA phosphatase
CEW83_04550	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CEW83_04585	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CEW83_04590	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CEW83_04600	COG1355	regulation of microtubule-based process
CEW83_04605	COG3885	ferrous iron binding
CEW83_04605	COG2078	PFAM AMMECR1 domain protein
CEW83_04625	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CEW83_04630	COG2205	protein histidine kinase activity
CEW83_04635	COG0745	RESPONSE REGULATOR receiver
CEW83_04640	COG2831	hemolysin activation secretion protein
CEW83_04660	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CEW83_04665	COG0560	Phosphoserine phosphatase
CEW83_04670	COG2866	Carboxypeptidase
CEW83_04675	COG3022	response to hydroperoxide
CEW83_04685	COG0156	8-amino-7-oxononanoate synthase activity
CEW83_04690	COG2267	carboxylic ester hydrolase activity
CEW83_04695	COG2226	methyltransferase
CEW83_04700	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CEW83_04705	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CEW83_04715	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CEW83_04720	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEW83_04725	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEW83_04730	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CEW83_04735	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CEW83_04755	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CEW83_04760	COG0575	Belongs to the CDS family
CEW83_04765	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CEW83_04770	COG0233	cytoplasmic translational termination
CEW83_04775	COG0528	UMP kinase activity
CEW83_04780	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CEW83_04785	COG0052	Belongs to the universal ribosomal protein uS2 family
CEW83_04790	COG0024	Methionine aminopeptidase
CEW83_04795	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CEW83_04820	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CEW83_04830	COG1196	nuclear chromosome segregation
CEW83_04835	COG0436	Aminotransferase
CEW83_04840	COG2171	N-acyltransferase activity
CEW83_04850	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CEW83_04860	COG0784	Response regulator, receiver
CEW83_04870	COG0633	Ferredoxin
CEW83_04875	COG0443	Heat shock 70 kDa protein
CEW83_04880	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CEW83_04890	COG0822	iron-sulfur transferase activity
CEW83_04895	COG1104	cysteine desulfurase activity
CEW83_04900	COG1104	cysteine desulfurase activity
CEW83_04910	COG1045	serine acetyltransferase
CEW83_04995	COG2326	polyphosphate kinase activity
CEW83_05025	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CEW83_05030	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CEW83_05035	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CEW83_05045	COG0356	it plays a direct role in the translocation of protons across the membrane
CEW83_05065	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CEW83_05080	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CEW83_05085	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CEW83_05095	COG4325	translation initiation factor activity
CEW83_05125	COG0519	Catalyzes the synthesis of GMP from XMP
CEW83_05125	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CEW83_05140	COG2914	Belongs to the UPF0125 (RnfH) family
CEW83_05150	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CEW83_05155	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CEW83_05160	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CEW83_05165	COG0601	transmembrane transport
CEW83_05175	COG3781	membrane
CEW83_05185	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CEW83_05190	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CEW83_05195	COG0509	glycine decarboxylation via glycine cleavage system
CEW83_05200	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CEW83_05200	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CEW83_05215	COG1215	transferase activity, transferring glycosyl groups
CEW83_05225	COG0583	DNA-binding transcription factor activity
CEW83_05235	COG1858	cytochrome C peroxidase
CEW83_05245	COG0386	Belongs to the glutathione peroxidase family
CEW83_05255	COG0488	(ABC) transporter
CEW83_05260	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CEW83_05275	COG0243	molybdopterin cofactor binding
CEW83_05310	COG0515	serine threonine protein kinase
CEW83_05310	COG2815	serine threonine protein kinase
CEW83_05325	COG1136	(ABC) transporter
CEW83_05335	COG1032	radical SAM domain protein
CEW83_05350	COG0537	adenosine 5'-monophosphoramidase activity
CEW83_05380	COG1196	nuclear chromosome segregation
CEW83_05405	COG1522	sequence-specific DNA binding
CEW83_05420	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CEW83_05430	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CEW83_05480	COG1280	lysine exporter protein (LysE YggA)
CEW83_05495	COG4106	trans-aconitate 2-methyltransferase activity
CEW83_05500	COG0318	PFAM AMP-dependent synthetase and ligase
CEW83_05540	COG0454	-acetyltransferase
CEW83_05570	COG1794	racemase activity, acting on amino acids and derivatives
CEW83_05580	COG1522	sequence-specific DNA binding
CEW83_05595	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CEW83_05600	COG1309	transcriptional regulator
CEW83_05605	COG1744	ABC transporter substrate-binding protein PnrA-like
CEW83_05625	COG0402	S-adenosylhomocysteine deaminase activity
CEW83_05630	COG1448	Aminotransferase
CEW83_05675	COG0625	glutathione transferase activity
CEW83_05685	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CEW83_05725	COG1490	D-aminoacyl-tRNA deacylase activity
CEW83_05730	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CEW83_05735	COG3842	ATPase activity
CEW83_05740	COG1176	ABC-type spermidine putrescine transport system, permease component I
CEW83_05745	COG1177	transmembrane transport
CEW83_05750	COG1115	amino acid carrier protein
CEW83_05780	COG3300	MHYT domain
CEW83_05780	COG5001	Diguanylate cyclase
CEW83_05785	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CEW83_05785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CEW83_05800	COG5001	Diguanylate cyclase
CEW83_05800	COG3447	MASE1 domain protein
CEW83_05800	COG5002	protein histidine kinase activity
CEW83_05805	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CEW83_05820	COG3706	GGDEF domain
CEW83_05840	COG1192	Involved in chromosome partitioning
CEW83_05860	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CEW83_05865	COG0587	DNA-directed DNA polymerase activity
CEW83_05875	COG0583	DNA-binding transcription factor activity
CEW83_05880	COG1063	alcohol dehydrogenase
CEW83_05900	COG0436	Aminotransferase
CEW83_05910	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CEW83_05915	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CEW83_05920	COG0840	transmembrane signaling receptor activity
CEW83_05935	COG0791	NLP P60 protein
CEW83_05945	COG1840	ABC-type Fe3 transport system, periplasmic component
CEW83_05950	COG1178	ABC-type Fe3 transport system permease component
CEW83_05955	COG3842	ATPase activity
CEW83_05960	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CEW83_05965	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CEW83_05970	COG0167	dihydroorotate dehydrogenase activity
CEW83_05975	COG4657	Part of a membrane complex involved in electron transport
CEW83_05980	COG2878	Part of a membrane complex involved in electron transport
CEW83_05985	COG4656	Part of a membrane complex involved in electron transport
CEW83_05995	COG4659	FMN binding
CEW83_06000	COG4660	Part of a membrane complex involved in electron transport
CEW83_06005	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CEW83_06025	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CEW83_06040	COG0426	domain, Protein
CEW83_06040	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CEW83_06045	COG1846	Transcriptional regulator
CEW83_06095	COG0326	Molecular chaperone. Has ATPase activity
CEW83_06105	COG3264	Mechanosensitive ion channel
CEW83_06105	COG1196	nuclear chromosome segregation
CEW83_06120	COG0596	Alpha beta hydrolase
CEW83_06135	COG1230	cation diffusion facilitator family transporter
CEW83_06145	COG3135	benzoate transporter
CEW83_06155	COG3259	Nickel-dependent hydrogenase
CEW83_06160	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
CEW83_06165	COG3383	formate dehydrogenase (NAD+) activity
CEW83_06170	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CEW83_06175	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CEW83_06185	COG2205	protein histidine kinase activity
CEW83_06185	COG3437	response regulator, receiver
CEW83_06185	COG3850	Histidine kinase
CEW83_06185	COG4999	Histidine kinase
CEW83_06200	COG3300	MHYT domain
CEW83_06200	COG5001	Diguanylate cyclase
CEW83_06220	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CEW83_06225	COG0824	Thioesterase
CEW83_06245	COG4771	TonB-dependent receptor
CEW83_06255	COG0348	domain, Protein
CEW83_06280	COG1999	signal sequence binding
CEW83_06290	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CEW83_06290	COG0047	phosphoribosylformylglycinamidine synthase activity
CEW83_06295	COG0671	phosphoesterase, PA-phosphatase related
CEW83_06305	COG0463	Glycosyl transferase, family 2
CEW83_06325	COG0741	lytic transglycosylase activity
CEW83_06325	COG0739	heme binding
CEW83_06325	COG1196	nuclear chromosome segregation
CEW83_06335	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CEW83_06345	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEW83_06350	COG0596	Alpha beta hydrolase
CEW83_06355	COG2133	pyrroloquinoline quinone binding
CEW83_06365	COG0625	glutathione transferase activity
CEW83_06435	COG1518	maintenance of DNA repeat elements
CEW83_06445	COG3328	transposase activity
CEW83_06470	COG1764	response to oxidative stress
CEW83_06480	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CEW83_06500	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CEW83_06520	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CEW83_06525	COG0006	proline dipeptidase activity
CEW83_06535	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CEW83_06540	COG2176	DNA-directed DNA polymerase activity
CEW83_06540	COG5002	protein histidine kinase activity
CEW83_06550	COG5002	protein histidine kinase activity
CEW83_06560	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CEW83_06575	COG2010	Cytochrome c
CEW83_06590	COG2814	Major facilitator Superfamily
CEW83_06630	COG2223	nitrite transmembrane transporter activity
CEW83_06640	COG0535	radical SAM domain protein
CEW83_06645	COG2116	formate transmembrane transporter activity
CEW83_06650	COG0515	serine threonine protein kinase
CEW83_06655	COG1279	arginine transmembrane transporter activity
CEW83_06665	COG0697	spore germination
CEW83_06695	COG3300	MHYT domain
CEW83_06695	COG5001	Diguanylate cyclase
CEW83_06735	COG3391	amine dehydrogenase activity
CEW83_06750	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CEW83_06750	COG1648	precorrin-2 dehydrogenase activity
CEW83_06755	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CEW83_06765	COG0840	transmembrane signaling receptor activity
CEW83_06785	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CEW83_06790	COG1185	polyribonucleotide nucleotidyltransferase activity
CEW83_06795	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CEW83_06800	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CEW83_06805	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CEW83_06810	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CEW83_06815	COG2251	uridine kinase activity
CEW83_06815	COG0195	Participates in both transcription termination and antitermination
CEW83_06820	COG0779	Required for maturation of 30S ribosomal subunits
CEW83_06830	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CEW83_06835	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CEW83_06840	COG0180	Tryptophanyl-tRNA synthetase
CEW83_06845	COG1994	Peptidase M50
CEW83_06850	COG0009	L-threonylcarbamoyladenylate synthase
CEW83_06855	COG0613	PHP domain protein
CEW83_06860	COG2267	carboxylic ester hydrolase activity
CEW83_06870	COG0542	response to heat
CEW83_06885	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CEW83_06890	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CEW83_06905	COG2154	pterin-4-alpha-carbinolamine dehydratase
CEW83_06915	COG2081	HI0933 family
CEW83_06950	COG0826	peptidase U32
CEW83_06980	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CEW83_06985	COG1278	Cold shock
CEW83_06990	COG0513	Belongs to the DEAD box helicase family
CEW83_07005	COG4681	YaeQ
CEW83_07020	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CEW83_07030	COG0302	gtp cyclohydrolase
CEW83_07040	COG0306	phosphate transporter
CEW83_07050	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CEW83_07055	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CEW83_07060	COG2233	PERMEase
CEW83_07075	COG4206	TonB-dependent receptor
CEW83_07080	COG2204	response regulator
CEW83_07105	COG0579	oxidoreductase
CEW83_07130	COG3647	Membrane
CEW83_07135	COG0348	domain, Protein
CEW83_07140	COG1959	2 iron, 2 sulfur cluster binding
CEW83_07150	COG2354	Protein conserved in bacteria
CEW83_07195	COG1741	Belongs to the pirin family
CEW83_07220	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CEW83_07225	COG1254	Belongs to the acylphosphatase family
CEW83_07235	COG0443	Heat shock 70 kDa protein
CEW83_07245	COG2195	Cleaves the N-terminal amino acid of tripeptides
CEW83_07265	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CEW83_07280	COG2816	NAD+ diphosphatase activity
CEW83_07285	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CEW83_07300	COG0356	it plays a direct role in the translocation of protons across the membrane
CEW83_07310	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CEW83_07310	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CEW83_07315	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CEW83_07325	COG1132	(ABC) transporter
CEW83_07340	COG1272	protein, Hemolysin III
CEW83_07350	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CEW83_07355	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEW83_07400	COG3706	GGDEF domain
CEW83_07440	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CEW83_07445	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CEW83_07450	COG0740	serine-type endopeptidase activity
CEW83_07455	COG0544	peptidyl-prolyl cis-trans isomerase activity
CEW83_07460	COG2766	serine protein kinase
CEW83_07465	COG2718	Belongs to the UPF0229 family
CEW83_07470	COG2719	SpoVR family
CEW83_07475	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CEW83_07475	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CEW83_07485	COG0697	spore germination
CEW83_07495	COG1595	DNA-templated transcription, initiation
CEW83_07505	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CEW83_07535	COG0438	transferase activity, transferring glycosyl groups
CEW83_07550	COG1183	phosphatidylcholine synthase activity
CEW83_07560	COG1403	HNH endonuclease
CEW83_07565	COG3360	Dodecin
CEW83_07585	COG1309	transcriptional regulator
CEW83_07600	COG1136	(ABC) transporter
CEW83_07610	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CEW83_07710	COG0009	L-threonylcarbamoyladenylate synthase
CEW83_07715	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CEW83_07720	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CEW83_07725	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CEW83_07735	COG4566	intracellular signal transduction
CEW83_07750	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CEW83_07755	COG0508	dehydrogenase complex catalyzes the overall conversion of
CEW83_07760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEW83_07795	COG0802	atpase or kinase
CEW83_07800	COG0860	N-Acetylmuramoyl-L-alanine amidase
CEW83_07805	COG0196	riboflavin kinase activity
CEW83_07810	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CEW83_07815	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CEW83_07820	COG1047	Peptidyl-prolyl cis-trans
CEW83_07825	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CEW83_07835	COG1722	exodeoxyribonuclease VII activity
CEW83_07840	COG0142	geranyltranstransferase activity
CEW83_07845	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CEW83_07850	COG1469	GTP cyclohydrolase I activity
CEW83_07855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CEW83_07865	COG0022	dehydrogenase e1 component
CEW83_07870	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CEW83_07890	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CEW83_07930	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CEW83_07940	COG0254	rRNA binding
CEW83_07950	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CEW83_07955	COG0501	Belongs to the peptidase M48B family
CEW83_07975	COG2308	Evidence 4 Homologs of previously reported genes of
CEW83_07980	COG0183	Belongs to the thiolase family
CEW83_08010	COG1666	GTP binding
CEW83_08015	COG3123	guanosine phosphorylase activity
CEW83_08025	COG0137	argininosuccinate synthase activity
CEW83_08030	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CEW83_08035	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CEW83_08045	COG0268	Binds directly to 16S ribosomal RNA
CEW83_08070	COG0563	adenylate kinase activity
CEW83_08075	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CEW83_08080	COG2835	tetraacyldisaccharide 4'-kinase activity
CEW83_08085	COG1663	tetraacyldisaccharide 4'-kinase activity
CEW83_08095	COG0811	peptide transport
CEW83_08100	COG1570	exodeoxyribonuclease VII activity
CEW83_08105	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CEW83_08110	COG0564	pseudouridine synthase activity
CEW83_08120	COG0643	Histidine kinase
CEW83_08120	COG2198	Histidine kinase
CEW83_08125	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CEW83_08130	COG0745	RESPONSE REGULATOR receiver
CEW83_08135	COG0835	chemotaxis
CEW83_08135	COG0784	Response regulator, receiver
CEW83_08140	COG0835	chemotaxis
CEW83_08140	COG0784	Response regulator, receiver
CEW83_08145	COG0840	transmembrane signaling receptor activity
CEW83_08150	COG2201	protein-glutamate methylesterase activity
CEW83_08165	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CEW83_08180	COG0745	RESPONSE REGULATOR receiver
CEW83_08180	COG3706	GGDEF domain
CEW83_08230	COG0457	Tetratricopeptide repeat
CEW83_08270	COG3754	Rhamnan synthesis protein F
CEW83_08285	COG1334	flagellar protein FlaG
CEW83_08290	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CEW83_08310	COG2257	FlhB HrpN YscU SpaS Family
CEW83_08315	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CEW83_08320	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CEW83_08325	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CEW83_08330	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CEW83_08335	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CEW83_08340	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CEW83_08345	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CEW83_08350	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CEW83_08365	COG3181	Tripartite tricarboxylate transporter family receptor
CEW83_08370	COG2721	sulfolactate sulfo-lyase activity
CEW83_08375	COG2721	sulfolactate sulfo-lyase activity
CEW83_08385	COG2188	Transcriptional regulator
CEW83_08390	COG2855	membrane
CEW83_08410	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CEW83_08430	COG1028	Short-chain dehydrogenase reductase Sdr
CEW83_08440	COG1677	Flagellar hook-basal body complex protein FliE
CEW83_08450	COG3852	Histidine kinase
CEW83_08460	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CEW83_08470	COG1157	protein secretion by the type III secretion system
CEW83_08480	COG0402	S-adenosylhomocysteine deaminase activity
CEW83_08495	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CEW83_08495	COG0662	Cupin 2, conserved barrel domain protein
CEW83_08500	COG0175	sulfate reduction
CEW83_08515	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CEW83_08535	COG0583	DNA-binding transcription factor activity
CEW83_08555	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CEW83_08575	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CEW83_08580	COG1028	Short-chain dehydrogenase reductase Sdr
CEW83_08590	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CEW83_08600	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CEW83_08600	COG0662	Cupin 2, conserved barrel domain protein
CEW83_08625	COG0438	transferase activity, transferring glycosyl groups
CEW83_08645	COG0489	protein tyrosine kinase activity
CEW83_08675	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CEW83_08680	COG3852	Histidine kinase
CEW83_08710	COG0471	metal ion transport
CEW83_08710	COG3273	potassium ion transport
CEW83_08740	COG2204	response regulator
CEW83_08760	COG3383	formate dehydrogenase (NAD+) activity
CEW83_08780	COG3706	GGDEF domain
CEW83_08845	COG0793	Belongs to the peptidase S41A family
CEW83_08875	COG0720	synthase
CEW83_08885	COG1511	domain protein
CEW83_08885	COG3264	Mechanosensitive ion channel
CEW83_08890	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CEW83_08895	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CEW83_08895	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CEW83_08905	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CEW83_08915	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CEW83_08920	COG1238	metal cluster binding
CEW83_08930	COG3300	MHYT domain
CEW83_08930	COG5001	Diguanylate cyclase
CEW83_08940	COG1793	dna ligase
CEW83_08945	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CEW83_08975	COG0028	Belongs to the TPP enzyme family
CEW83_08980	COG0440	acetolactate synthase activity
CEW83_08985	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CEW83_09000	COG0745	RESPONSE REGULATOR receiver
CEW83_09005	COG2205	protein histidine kinase activity
CEW83_09010	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CEW83_09015	COG1183	phosphatidylcholine synthase activity
CEW83_09030	COG0642	Histidine kinase
CEW83_09040	COG3642	lipopolysaccharide core region biosynthetic process
CEW83_09050	COG2205	protein histidine kinase activity
CEW83_09055	COG0745	RESPONSE REGULATOR receiver
CEW83_09065	COG1858	cytochrome C peroxidase
CEW83_09075	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CEW83_09080	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CEW83_09095	COG1295	ribonuclease BN
CEW83_09105	COG0228	four-way junction DNA binding
CEW83_09110	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CEW83_09115	COG0336	Belongs to the RNA methyltransferase TrmD family
CEW83_09120	COG0335	large ribosomal subunit rRNA binding
CEW83_09130	COG0795	lipopolysaccharide-transporting ATPase activity
CEW83_09135	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CEW83_09150	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CEW83_09160	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CEW83_09165	COG0583	DNA-binding transcription factor activity
CEW83_09170	COG0525	valine-tRNA ligase activity
CEW83_09175	COG0425	Belongs to the sulfur carrier protein TusA family
CEW83_09180	COG4783	chaperone-mediated protein folding
CEW83_09185	COG0315	cyclic pyranopterin monophosphate synthase activity
CEW83_09200	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CEW83_09220	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CEW83_09225	COG2414	aldehyde ferredoxin oxidoreductase
CEW83_09235	COG3284	Transcriptional regulator
CEW83_09260	COG1012	belongs to the aldehyde dehydrogenase family
CEW83_09265	COG3284	Transcriptional regulator
CEW83_09285	COG0784	Response regulator, receiver
CEW83_09285	COG4191	Histidine kinase
CEW83_09290	COG0318	PFAM AMP-dependent synthetase and ligase
CEW83_09295	COG1960	acyl-CoA dehydrogenase activity
CEW83_09305	COG0659	secondary active sulfate transmembrane transporter activity
CEW83_09325	COG4172	Belongs to the ABC transporter superfamily
CEW83_09330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CEW83_09335	COG0601	transmembrane transport
CEW83_09340	COG0747	negative chemotaxis
CEW83_09350	COG0583	DNA-binding transcription factor activity
CEW83_09370	COG3264	Mechanosensitive ion channel
CEW83_09370	COG1511	domain protein
CEW83_09405	COG1131	(ABC) transporter
CEW83_09475	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEW83_09485	COG0583	DNA-binding transcription factor activity
CEW83_09510	COG0247	lactate metabolic process
CEW83_09535	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CEW83_09595	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CEW83_09605	COG1454	alcohol dehydrogenase
CEW83_09620	COG4772	TonB-dependent receptor
CEW83_09635	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CEW83_09645	COG1012	belongs to the aldehyde dehydrogenase family
CEW83_09650	COG0693	protein deglycase activity
CEW83_09660	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CEW83_09660	COG0644	oxidoreductase
CEW83_09665	COG0837	glucose binding
CEW83_09670	COG0166	Belongs to the GPI family
CEW83_09685	COG0142	geranyltranstransferase activity
CEW83_09690	COG0584	glycerophosphoryl diester phosphodiesterase
CEW83_09705	COG0667	Aldo Keto reductase
CEW83_09710	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
CEW83_09715	COG0513	Belongs to the DEAD box helicase family
CEW83_09725	COG1428	Deoxynucleoside kinase
CEW83_09730	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CEW83_09735	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CEW83_09740	COG0517	IMP dehydrogenase activity
CEW83_09740	COG0516	GMP reductase activity
CEW83_09745	COG0308	aminopeptidase N
CEW83_09775	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CEW83_09785	COG0589	response to stress
CEW83_09790	COG0538	isocitrate dehydrogenase activity
CEW83_09795	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
CEW83_09825	COG4654	Cytochrome c, class I
CEW83_09830	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CEW83_09835	COG0640	Transcriptional regulator
CEW83_09845	COG0446	pyridine nucleotide-disulphide oxidoreductase
CEW83_09860	COG0756	dUTP diphosphatase activity
CEW83_09865	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CEW83_09870	COG2003	Belongs to the UPF0758 family
CEW83_09875	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CEW83_09880	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CEW83_09885	COG1278	Cold shock
CEW83_09890	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CEW83_09895	COG0542	response to heat
CEW83_09900	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CEW83_09905	COG2224	Isocitrate lyase
CEW83_09915	COG0745	RESPONSE REGULATOR receiver
CEW83_09920	COG2205	protein histidine kinase activity
CEW83_09925	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CEW83_09930	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CEW83_09950	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CEW83_09955	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CEW83_09960	COG0739	heme binding
CEW83_09965	COG0316	Belongs to the HesB IscA family
CEW83_09970	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CEW83_09975	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CEW83_09985	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CEW83_09995	COG0494	nUDIX hydrolase
CEW83_10000	COG0442	prolyl-tRNA aminoacylation
CEW83_10005	COG0741	lytic transglycosylase activity
CEW83_10020	COG0312	modulator of DNA gyrase
CEW83_10025	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CEW83_10035	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CEW83_10040	COG5607	PFAM CHAD domain containing protein
CEW83_10040	COG3025	triphosphatase activity
CEW83_10060	COG0482	sulfurtransferase activity
CEW83_10090	COG0429	hydrolase of the alpha beta-hydrolase fold
CEW83_10100	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CEW83_10105	COG2096	Adenosyltransferase
CEW83_10110	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CEW83_10120	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CEW83_10125	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CEW83_10130	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CEW83_10135	COG0521	Mo-molybdopterin cofactor biosynthetic process
CEW83_10140	COG3028	Belongs to the UPF0307 family
CEW83_10145	COG0312	modulator of DNA gyrase
CEW83_10155	COG2951	lytic endotransglycosylase activity
CEW83_10170	COG1346	cytolysis
CEW83_10180	COG5002	protein histidine kinase activity
CEW83_10185	COG0745	RESPONSE REGULATOR receiver
CEW83_10195	COG4251	negative regulation of phosphorylation
CEW83_10205	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEW83_10210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEW83_10215	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CEW83_10220	COG0628	permease
CEW83_10225	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CEW83_10235	COG0617	tRNA 3'-terminal CCA addition
CEW83_10255	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CEW83_10260	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CEW83_10265	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CEW83_10275	COG0247	lactate metabolic process
CEW83_10280	COG0277	FAD linked oxidase domain protein
CEW83_10285	COG0277	FAD linked oxidase domain protein
CEW83_10300	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CEW83_10305	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CEW83_10310	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CEW83_10315	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CEW83_10330	COG3320	Male sterility
CEW83_10330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEW83_10345	COG4591	ABC-type transport system involved in lipoprotein release permease component
CEW83_10360	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CEW83_10370	COG0604	alcohol dehydrogenase
CEW83_10380	COG1704	LemA family
CEW83_10410	COG1196	nuclear chromosome segregation
CEW83_10410	COG0741	lytic transglycosylase activity
CEW83_10410	COG0739	heme binding
CEW83_10425	COG2204	response regulator
CEW83_10430	COG4191	Histidine kinase
CEW83_10435	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CEW83_10440	COG2030	dehydratase
CEW83_10475	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
CEW83_10515	COG0426	domain, Protein
CEW83_10525	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CEW83_10550	COG4657	Part of a membrane complex involved in electron transport
CEW83_10570	COG4659	FMN binding
CEW83_10580	COG2914	Belongs to the UPF0125 (RnfH) family
CEW83_10610	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CEW83_10620	COG4536	flavin adenine dinucleotide binding
CEW83_10635	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CEW83_10650	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CEW83_10665	COG0733	neurotransmitter:sodium symporter activity
CEW83_10670	COG1522	sequence-specific DNA binding
CEW83_10680	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEW83_10690	COG0134	indole-3-glycerol-phosphate synthase activity
CEW83_10695	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CEW83_10710	COG0546	phosphoglycolate phosphatase activity
CEW83_10720	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CEW83_10725	COG5212	phosphodiesterase
CEW83_10740	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CEW83_10745	COG0045	succinate-CoA ligase (ADP-forming) activity
CEW83_10760	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CEW83_10770	COG0805	protein transport
CEW83_10775	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CEW83_10780	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CEW83_10790	COG0140	phosphoribosyl-ATP diphosphatase activity
CEW83_10795	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CEW83_10800	COG0107	imidazoleglycerol-phosphate synthase activity
CEW83_10805	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CEW83_10810	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CEW83_10815	COG0131	Imidazoleglycerol-phosphate dehydratase
CEW83_10820	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CEW83_10825	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CEW83_10830	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CEW83_10835	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CEW83_10840	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CEW83_10850	COG0842	Transport permease protein
CEW83_10855	COG1131	(ABC) transporter
CEW83_10875	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CEW83_10880	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CEW83_10885	COG1127	ABC transporter
CEW83_10950	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CEW83_10955	COG1024	Enoyl-CoA hydratase
CEW83_10970	COG0204	Acyl-transferase
CEW83_10975	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CEW83_10980	COG0751	glycine-tRNA ligase activity
CEW83_10985	COG0752	glycyl-tRNA synthetase alpha subunit
CEW83_10990	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CEW83_10995	COG4535	Mg2 and Co2 transporter CorC
CEW83_11000	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CEW83_11005	COG1702	phosphate starvation-inducible protein PhoH
CEW83_11010	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CEW83_11025	COG1739	Uncharacterized protein family UPF0029
CEW83_11050	COG2308	Evidence 4 Homologs of previously reported genes of
CEW83_11055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEW83_11080	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
CEW83_11085	COG1607	acyl-coa hydrolase
CEW83_11090	COG3634	alkyl hydroperoxide reductase activity
CEW83_11105	COG2177	Part of the ABC transporter FtsEX involved in
CEW83_11110	COG2884	Cell division ATP-binding protein ftsE
CEW83_11120	COG0612	Peptidase, M16
CEW83_11125	COG0612	Peptidase, M16
CEW83_11130	COG0742	ribosomal rna small subunit methyltransferase
CEW83_11135	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CEW83_11140	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CEW83_11145	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CEW83_11150	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CEW83_11160	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CEW83_11165	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CEW83_11175	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CEW83_11180	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CEW83_11185	COG0193	aminoacyl-tRNA hydrolase activity
CEW83_11190	COG0012	GTP binding
CEW83_11195	COG3002	Belongs to the UPF0753 family
CEW83_11200	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CEW83_11210	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CEW83_11215	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CEW83_11215	COG2169	Transcriptional regulator
CEW83_11230	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CEW83_11235	COG1053	succinate dehydrogenase
CEW83_11255	COG4263	nitrous-oxide reductase activity
CEW83_11280	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CEW83_11310	COG0454	-acetyltransferase
CEW83_11310	COG0456	acetyltransferase
CEW83_11330	COG1115	amino acid carrier protein
CEW83_11335	COG0583	DNA-binding transcription factor activity
CEW83_11340	COG0477	Major facilitator Superfamily
CEW83_11380	COG1595	DNA-templated transcription, initiation
CEW83_11390	COG1944	ATP diphosphatase activity
CEW83_11430	COG3459	Glycosyltransferase 36 associated
CEW83_11445	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CEW83_11450	COG0798	PFAM Bile acid sodium symporter
CEW83_11465	COG0583	DNA-binding transcription factor activity
CEW83_11470	COG1741	Belongs to the pirin family
CEW83_11490	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CEW83_11495	COG3842	ATPase activity
CEW83_11500	COG1177	transmembrane transport
CEW83_11505	COG1176	ABC-type spermidine putrescine transport system, permease component I
CEW83_11515	COG1349	DNA-binding transcription factor activity
CEW83_11520	COG2267	carboxylic ester hydrolase activity
CEW83_11525	COG0697	spore germination
CEW83_11565	COG0463	Glycosyl transferase, family 2
CEW83_11610	COG0436	Aminotransferase
CEW83_11615	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CEW83_11620	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CEW83_11620	COG0235	Class ii aldolase
CEW83_11630	COG2084	Dehydrogenase
CEW83_11635	COG2084	Dehydrogenase
CEW83_11640	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CEW83_11650	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CEW83_11660	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CEW83_11690	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CEW83_11700	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CEW83_11710	COG0784	Response regulator, receiver
CEW83_11715	COG4251	negative regulation of phosphorylation
CEW83_11725	COG0629	single-stranded DNA binding
CEW83_11730	COG2814	Major facilitator Superfamily
CEW83_11745	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CEW83_11750	COG0203	ribosomal protein L17
CEW83_11755	COG0202	RNA polymerase activity
CEW83_11760	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CEW83_11765	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CEW83_11770	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CEW83_11775	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CEW83_11780	COG0201	protein transport
CEW83_11785	COG0200	Binds to the 23S rRNA
CEW83_11790	COG1841	ribosomal large subunit assembly
CEW83_11795	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CEW83_11800	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CEW83_11805	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CEW83_11810	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CEW83_11815	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CEW83_11820	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CEW83_11825	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CEW83_11830	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CEW83_11835	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CEW83_11840	COG0255	Belongs to the universal ribosomal protein uL29 family
CEW83_11845	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CEW83_11850	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CEW83_11855	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CEW83_11860	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CEW83_11865	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CEW83_11870	COG0089	rRNA binding
CEW83_11875	COG0088	Forms part of the polypeptide exit tunnel
CEW83_11880	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CEW83_11885	COG0051	transcription antitermination factor activity, RNA binding
CEW83_11890	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CEW83_11895	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CEW83_11900	COG0049	tRNA binding
CEW83_11905	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CEW83_11910	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CEW83_11915	COG0085	RNA polymerase activity
CEW83_11920	COG0222	ribosome binding
CEW83_11925	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CEW83_11930	COG0081	regulation of translation
CEW83_11935	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CEW83_11945	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CEW83_11955	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CEW83_11980	COG5265	(ABC) transporter
CEW83_12005	COG0252	asparaginase activity
CEW83_12010	COG0583	DNA-binding transcription factor activity
CEW83_12015	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CEW83_12025	COG0175	sulfate reduction
CEW83_12030	COG0175	sulfate reduction
CEW83_12040	COG2895	sulfate adenylyltransferase (ATP) activity
CEW83_12055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CEW83_12065	COG0501	Belongs to the peptidase M48B family
CEW83_12070	COG0513	Belongs to the DEAD box helicase family
CEW83_12075	COG0778	Nitroreductase
CEW83_12090	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
CEW83_12100	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CEW83_12135	COG0427	acetyl-CoA hydrolase
CEW83_12185	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CEW83_12190	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CEW83_12195	COG1538	Outer membrane efflux protein
CEW83_12200	COG0745	RESPONSE REGULATOR receiver
CEW83_12205	COG2205	protein histidine kinase activity
CEW83_12220	COG2818	Glycosylase
CEW83_12230	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CEW83_12240	COG2070	2-Nitropropane dioxygenase
CEW83_12270	COG1764	response to oxidative stress
CEW83_12290	COG0583	DNA-binding transcription factor activity
CEW83_12365	COG0628	permease
CEW83_12370	COG2823	Periplasmic or secreted lipoprotein
CEW83_12380	COG5487	UPF0391 membrane protein
CEW83_12410	COG0789	Transcriptional regulator
CEW83_12430	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CEW83_12435	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CEW83_12445	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CEW83_12460	COG0069	glutamate synthase activity
CEW83_12460	COG0070	glutamate synthase
CEW83_12460	COG0067	glutamate synthase
CEW83_12465	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CEW83_12470	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CEW83_12475	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CEW83_12510	COG1965	Belongs to the frataxin family
CEW83_12540	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CEW83_12545	COG0284	orotidine-5'-phosphate decarboxylase activity
CEW83_12550	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CEW83_12555	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CEW83_12565	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
CEW83_12610	COG1805	sodium ion transport
CEW83_12620	COG0183	Belongs to the thiolase family
CEW83_12625	COG1024	Enoyl-CoA hydratase
CEW83_12625	COG1250	3-hydroxyacyl-CoA dehydrogenase
CEW83_12630	COG2067	long-chain fatty acid transport protein
CEW83_12640	COG1024	Enoyl-CoA hydratase
CEW83_12640	COG1250	3-hydroxyacyl-CoA dehydrogenase
CEW83_12650	COG1960	acyl-CoA dehydrogenase activity
CEW83_12675	COG0523	cobalamin synthesis protein
CEW83_12680	COG0277	FAD linked oxidase domain protein
CEW83_12700	COG2197	response regulator
CEW83_12720	COG2205	protein histidine kinase activity
CEW83_12720	COG2198	Histidine kinase
CEW83_12720	COG0784	Response regulator, receiver
CEW83_12755	COG0559	Belongs to the binding-protein-dependent transport system permease family
CEW83_12765	COG1022	Amp-dependent synthetase and ligase
CEW83_12770	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CEW83_12770	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CEW83_12770	COG1703	isobutyryl-CoA mutase activity
CEW83_12780	COG0784	Response regulator, receiver
CEW83_12780	COG4191	Histidine kinase
CEW83_12795	COG2321	neutral zinc metallopeptidase
CEW83_12810	COG0439	Biotin carboxylase
CEW83_12815	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CEW83_12820	COG1703	isobutyryl-CoA mutase activity
CEW83_12825	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CEW83_12825	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CEW83_12830	COG1802	Transcriptional regulator
CEW83_12835	COG1253	flavin adenine dinucleotide binding
CEW83_12840	COG0114	fumarate hydratase activity
CEW83_12845	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CEW83_12850	COG3162	membrane
CEW83_12855	COG1024	Enoyl-CoA hydratase
CEW83_12860	COG1492	cobalamin metabolic process
CEW83_12895	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CEW83_12900	COG1999	signal sequence binding
CEW83_12905	COG0109	protoheme IX farnesyltransferase activity
CEW83_12940	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
CEW83_12945	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CEW83_12960	COG0300	oxidoreductase activity
CEW83_12980	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CEW83_12995	COG1469	GTP cyclohydrolase I activity
CEW83_13025	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CEW83_13030	COG1832	CoA-binding protein
CEW83_13035	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CEW83_13040	COG3568	Endonuclease Exonuclease Phosphatase
CEW83_13045	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CEW83_13070	COG3852	Histidine kinase
CEW83_13085	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CEW83_13095	COG0237	dephospho-CoA kinase activity
CEW83_13100	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CEW83_13105	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CEW83_13110	COG0494	nUDIX hydrolase
CEW83_13120	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CEW83_13125	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CEW83_13130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CEW83_13160	COG0305	Participates in initiation and elongation during chromosome replication
CEW83_13165	COG0359	binds to the 23S rRNA
CEW83_13170	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CEW83_13175	COG2965	DNA replication, synthesis of RNA primer
CEW83_13180	COG0360	Binds together with S18 to 16S ribosomal RNA
CEW83_13190	COG1643	Atp-dependent helicase
CEW83_13210	COG1968	undecaprenyl-diphosphatase activity
CEW83_13215	COG3150	esterase
CEW83_13220	COG2226	methyltransferase
CEW83_13225	COG2962	Rard protein
CEW83_13230	COG0557	exoribonuclease II activity
CEW83_13240	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CEW83_13245	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CEW83_13250	COG2239	Acts as a magnesium transporter
CEW83_13255	COG2119	membrane
CEW83_13260	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CEW83_13265	COG0352	thiamine-phosphate diphosphorylase activity
CEW83_13275	COG1773	rubredoxin
CEW83_13295	COG0840	transmembrane signaling receptor activity
CEW83_13300	COG0643	Histidine kinase
CEW83_13300	COG2198	Histidine kinase
CEW83_13305	COG0415	Belongs to the DNA photolyase family
CEW83_13310	COG1678	Uncharacterized ACR, COG1678
CEW83_13315	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CEW83_13320	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CEW83_13325	COG0540	Belongs to the ATCase OTCase family
CEW83_13335	COG1872	DUF167
CEW83_13340	COG0762	integral membrane protein
CEW83_13385	COG0437	4 iron, 4 sulfur cluster binding
CEW83_13425	COG0746	molybdenum cofactor guanylyltransferase activity
CEW83_13435	COG1763	Mo-molybdopterin cofactor biosynthetic process
CEW83_13440	COG4191	Histidine kinase
CEW83_13465	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CEW83_13470	COG3852	Histidine kinase
CEW83_13480	COG4654	Cytochrome c, class I
CEW83_13490	COG4302	ethanolamine ammonia-lyase activity
CEW83_13500	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CEW83_13505	COG0830	nickel cation binding
CEW83_13510	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CEW83_13515	COG0804	urea catabolic process
CEW83_13520	COG0832	Belongs to the urease beta subunit family
CEW83_13530	COG0831	urea catabolic process
CEW83_13535	COG0829	nickel cation binding
CEW83_13540	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CEW83_13540	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CEW83_13545	COG0659	secondary active sulfate transmembrane transporter activity
CEW83_13590	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CEW83_13595	COG1116	anion transmembrane transporter activity
CEW83_13600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CEW83_13605	COG0583	DNA-binding transcription factor activity
CEW83_13625	COG0559	Belongs to the binding-protein-dependent transport system permease family
CEW83_13645	COG3047	cAMP biosynthetic process
CEW83_13650	COG0513	Belongs to the DEAD box helicase family
CEW83_13660	COG1451	nucleotide metabolic process
CEW83_13665	COG1132	(ABC) transporter
CEW83_13670	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEW83_13680	COG5002	protein histidine kinase activity
CEW83_13680	COG2198	Histidine kinase
CEW83_13680	COG0784	Response regulator, receiver
CEW83_13685	COG1538	Outer membrane efflux protein
CEW83_13695	COG2203	Gaf domain
CEW83_13695	COG2200	EAL domain
CEW83_13695	COG2199	diguanylate cyclase activity
CEW83_13710	COG2197	response regulator
CEW83_13715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEW83_13720	COG2274	protein secretion by the type I secretion system
CEW83_13740	COG1136	(ABC) transporter
CEW83_13750	COG0735	belongs to the Fur family
CEW83_13755	COG1121	(ABC) transporter
CEW83_13765	COG0803	Belongs to the bacterial solute-binding protein 9 family
CEW83_13770	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CEW83_13775	COG1074	ATP-dependent DNA helicase activity
CEW83_13780	COG0688	phosphatidylethanolamine metabolic process
CEW83_13785	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CEW83_13790	COG3530	Putative quorum-sensing-regulated virulence factor
CEW83_13795	COG2095	MarC family integral membrane protein
CEW83_13805	COG1160	GTP binding
CEW83_13815	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CEW83_13820	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CEW83_13825	COG1538	Outer membrane efflux protein
CEW83_13830	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEW83_13835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEW83_13845	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CEW83_13865	COG0419	ATPase involved in DNA repair
CEW83_13870	COG0420	3'-5' exonuclease activity
CEW83_13885	COG1028	Short-chain dehydrogenase reductase Sdr
CEW83_13895	COG0432	Pfam Uncharacterised protein family UPF0047
CEW83_13910	COG0616	signal peptide processing
CEW83_13915	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CEW83_13920	COG2022	thiamine diphosphate biosynthetic process
CEW83_13930	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CEW83_13940	COG1126	abc transporter atp-binding protein
CEW83_13945	COG0765	amino acid transport
CEW83_13950	COG4597	amino acid ABC transporter
CEW83_13955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEW83_13970	COG2814	Major facilitator Superfamily
CEW83_13990	COG0288	reversible hydration of carbon dioxide
CEW83_13995	COG1940	carbohydrate kinase activity
CEW83_14000	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CEW83_14005	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CEW83_14015	COG0569	domain protein
CEW83_14020	COG2204	response regulator
CEW83_14025	COG5000	phosphorelay sensor kinase activity
CEW83_14055	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CEW83_14060	COG0706	membrane insertase activity
CEW83_14065	COG0594	ribonuclease P activity
CEW83_14070	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CEW83_14075	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CEW83_14115	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CEW83_14205	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CEW83_14235	COG3586	endonuclease activity
CEW83_14240	COG3311	Transcriptional regulator
CEW83_14245	COG1569	PIN domain
CEW83_14260	COG0583	DNA-binding transcription factor activity
CEW83_14270	COG0527	aspartate kinase activity
CEW83_14280	COG1858	cytochrome C peroxidase
CEW83_14290	COG1131	(ABC) transporter
CEW83_14295	COG0842	Transport permease protein
CEW83_14310	COG0583	DNA-binding transcription factor activity
CEW83_14340	COG3040	lipid binding
CEW83_14370	COG3842	ATPase activity
CEW83_14380	COG1176	ABC-type spermidine putrescine transport system, permease component I
CEW83_14385	COG1177	transmembrane transport
CEW83_14400	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CEW83_14405	COG1984	allophanate hydrolase subunit 2
CEW83_14410	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CEW83_14435	COG0783	Belongs to the Dps family
CEW83_14445	COG4206	TonB-dependent receptor
CEW83_14450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CEW83_14455	COG3706	GGDEF domain
CEW83_14465	COG3909	cytochrome
CEW83_14475	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CEW83_14485	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CEW83_14495	COG1187	pseudouridine synthase activity
CEW83_14505	COG2974	May be involved in recombination
CEW83_14510	COG1454	alcohol dehydrogenase
CEW83_14525	COG1454	alcohol dehydrogenase
CEW83_14530	COG0410	ABC transporter
CEW83_14535	COG1137	ATPase activity
CEW83_14545	COG0559	Belongs to the binding-protein-dependent transport system permease family
CEW83_14560	COG2204	response regulator
CEW83_14565	COG3852	Histidine kinase
CEW83_14575	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CEW83_14585	COG2922	Belongs to the Smg family
CEW83_14590	COG0758	DNA mediated transformation
CEW83_14600	COG0242	peptide deformylase activity
CEW83_14605	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CEW83_14610	COG0501	Belongs to the peptidase M48B family
CEW83_14615	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEW83_14620	COG1305	Transglutaminase-like
CEW83_14630	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CEW83_14635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEW83_14645	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CEW83_14665	COG0583	DNA-binding transcription factor activity
CEW83_14670	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CEW83_14680	COG0583	DNA-binding transcription factor activity
CEW83_14715	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CEW83_14720	COG0431	NADPH-dependent FMN reductase
CEW83_14725	COG1393	Belongs to the ArsC family
CEW83_14765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEW83_14770	COG0577	efflux transmembrane transporter activity
CEW83_14770	COG1136	(ABC) transporter
CEW83_14775	COG0577	efflux transmembrane transporter activity
CEW83_14775	COG1136	(ABC) transporter
CEW83_14790	COG1278	Cold shock
CEW83_14795	COG0535	radical SAM domain protein
CEW83_14805	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
CEW83_14810	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CEW83_14830	COG0583	DNA-binding transcription factor activity
CEW83_14855	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CEW83_14905	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CEW83_14905	COG3608	succinylglutamate desuccinylase aspartoacylase
CEW83_14935	COG0633	Ferredoxin
CEW83_14935	COG3217	Mosc domain protein beta barrel domain protein
CEW83_14940	COG3706	GGDEF domain
CEW83_14950	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CEW83_14975	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CEW83_14980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CEW83_14985	COG1116	anion transmembrane transporter activity
CEW83_14985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CEW83_14990	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
CEW83_15015	COG2249	NAD(P)H dehydrogenase (quinone) activity
CEW83_15025	COG0697	spore germination
CEW83_15030	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CEW83_15035	COG0784	Response regulator, receiver
CEW83_15035	COG2205	protein histidine kinase activity
CEW83_15035	COG5002	protein histidine kinase activity
CEW83_15040	COG3437	response regulator, receiver
CEW83_15045	COG0445	tRNA wobble uridine modification
CEW83_15050	COG0357	Ribosomal RNA small subunit methyltransferase G
CEW83_15055	COG1192	Involved in chromosome partitioning
CEW83_15060	COG1475	DNA binding
CEW83_15080	COG0356	it plays a direct role in the translocation of protons across the membrane
CEW83_15090	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CEW83_15095	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CEW83_15100	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CEW83_15105	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CEW83_15110	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CEW83_15115	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CEW83_15130	COG2226	methyltransferase
CEW83_15140	COG0745	RESPONSE REGULATOR receiver
CEW83_15160	COG0121	glutamine amidotransferase
CEW83_15165	COG2391	methyltransferase activity
CEW83_15175	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CEW83_15185	COG0154	amidase activity
CEW83_15190	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CEW83_15195	COG1077	Cell shape determining protein MreB Mrl
CEW83_15210	COG0768	penicillin binding
CEW83_15215	COG0772	Belongs to the SEDS family
CEW83_15225	COG1686	Belongs to the peptidase S11 family
CEW83_15235	COG2921	Belongs to the UPF0250 family
CEW83_15240	COG0321	lipoyl(octanoyl) transferase activity
CEW83_15245	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CEW83_15260	COG0210	DNA helicase
CEW83_15270	COG3706	GGDEF domain
CEW83_15275	COG0741	lytic transglycosylase activity
CEW83_15285	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CEW83_15300	COG1309	transcriptional regulator
CEW83_15305	COG0604	alcohol dehydrogenase
CEW83_15330	COG0765	amino acid transport
CEW83_15345	COG0583	DNA-binding transcription factor activity
CEW83_15390	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CEW83_15395	COG0022	dehydrogenase e1 component
CEW83_15405	COG0508	dehydrogenase complex catalyzes the overall conversion of
CEW83_15410	COG0095	Lipoate-protein ligase
CEW83_15435	COG3284	Transcriptional regulator
CEW83_15450	COG4628	conserved protein (DUF2132)
CEW83_15455	COG2066	Belongs to the glutaminase family
CEW83_15485	COG1063	alcohol dehydrogenase
CEW83_15495	COG1397	ADP-ribosylglycohydrolase
CEW83_15530	COG2755	lipolytic protein G-D-S-L family
CEW83_15550	COG0471	metal ion transport
CEW83_15570	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CEW83_15580	COG1053	succinate dehydrogenase
CEW83_15590	COG1012	belongs to the aldehyde dehydrogenase family
CEW83_15615	COG0583	DNA-binding transcription factor activity
CEW83_15630	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CEW83_15640	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CEW83_15645	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CEW83_15650	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CEW83_15660	COG0515	serine threonine protein kinase
CEW83_15660	COG2815	serine threonine protein kinase
CEW83_15665	COG1561	YicC-like family, N-terminal region
CEW83_15685	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CEW83_15705	COG0411	ABC transporter
CEW83_15735	COG0194	GDP metabolic process
CEW83_15740	COG1758	RNA polymerase activity
CEW83_15745	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CEW83_15755	COG2226	methyltransferase
CEW83_15760	COG0322	excinuclease ABC activity
CEW83_15770	COG3850	Histidine kinase
CEW83_15775	COG2197	response regulator
CEW83_15790	COG0243	molybdopterin cofactor binding
CEW83_15795	COG0437	4 iron, 4 sulfur cluster binding
CEW83_15800	COG0348	domain, Protein
CEW83_15805	COG3043	anaerobic respiration
CEW83_15810	COG3005	denitrification pathway
CEW83_15815	COG4133	protoheme IX ABC transporter activity
CEW83_15820	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CEW83_15835	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CEW83_15845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEW83_15860	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CEW83_15895	COG5001	Diguanylate cyclase
CEW83_15900	COG0475	glutathione-regulated potassium exporter activity
CEW83_15920	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CEW83_15930	COG0726	polysaccharide deacetylase
CEW83_15935	COG1752	Esterase of the alpha-beta hydrolase superfamily
CEW83_15985	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEW83_15995	COG1131	(ABC) transporter
CEW83_16010	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CEW83_16020	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CEW83_16045	COG1012	belongs to the aldehyde dehydrogenase family
CEW83_16050	COG1024	Enoyl-CoA hydratase
CEW83_16055	COG1250	3-hydroxyacyl-CoA dehydrogenase
CEW83_16060	COG2050	protein possibly involved in aromatic compounds catabolism
CEW83_16070	COG3396	Phenylacetate-CoA oxygenase
CEW83_16075	COG3460	Phenylacetate-CoA oxygenase
CEW83_16080	COG3396	Phenylacetate-CoA oxygenase
CEW83_16085	COG2151	metal-sulfur cluster biosynthetic enzyme
CEW83_16090	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CEW83_16100	COG0183	Belongs to the thiolase family
CEW83_16115	COG0411	ABC transporter
CEW83_16130	COG0776	regulation of translation
CEW83_16135	COG0513	Belongs to the DEAD box helicase family
CEW83_16140	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CEW83_16145	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CEW83_16160	COG4232	protein-disulfide reductase activity
CEW83_16195	COG3706	GGDEF domain
CEW83_16200	COG0534	Mate efflux family protein
CEW83_16235	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CEW83_16245	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CEW83_16250	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CEW83_16265	COG3706	GGDEF domain
CEW83_16265	COG4251	negative regulation of phosphorylation
CEW83_16265	COG5001	Diguanylate cyclase
CEW83_16265	COG2203	Gaf domain
CEW83_16275	COG3706	GGDEF domain
CEW83_16275	COG0745	RESPONSE REGULATOR receiver
CEW83_16310	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CEW83_16315	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CEW83_16330	COG2824	Alkylphosphonate utilization operon protein PhnA
CEW83_16335	COG0366	Alpha amylase catalytic
CEW83_16345	COG4178	(ABC) transporter
CEW83_16355	COG0366	Alpha amylase catalytic
CEW83_16360	COG5001	Diguanylate cyclase
CEW83_16360	COG3300	MHYT domain
CEW83_16370	COG3706	GGDEF domain
CEW83_16395	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CEW83_16400	COG0714	Associated with various cellular activities
CEW83_16405	COG2703	oxygen carrier activity
CEW83_16410	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CEW83_16420	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CEW83_16425	COG0235	Class ii aldolase
CEW83_16445	COG3971	2-oxopent-4-enoate hydratase activity
CEW83_16455	COG3384	dioxygenase
CEW83_16460	COG1012	belongs to the aldehyde dehydrogenase family
CEW83_16470	COG0179	Fumarylacetoacetate (FAA) hydrolase
CEW83_16485	COG1846	Transcriptional regulator
CEW83_16500	COG1024	Enoyl-CoA hydratase
CEW83_16510	COG1024	Enoyl-CoA hydratase
CEW83_16520	COG0446	pyridine nucleotide-disulphide oxidoreductase
CEW83_16540	COG0625	glutathione transferase activity
CEW83_16565	COG0583	DNA-binding transcription factor activity
CEW83_16595	COG0642	Histidine kinase
CEW83_16615	COG0347	Belongs to the P(II) protein family
CEW83_16620	COG0004	ammonium transporteR
CEW83_16645	COG0446	pyridine nucleotide-disulphide oxidoreductase
CEW83_16645	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CEW83_16655	COG0174	glutamine synthetase
CEW83_16660	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CEW83_16670	COG0069	glutamate synthase activity
CEW83_16675	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CEW83_16680	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CEW83_16695	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CEW83_16715	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CEW83_16725	COG3850	Histidine kinase
CEW83_16730	COG2197	response regulator
CEW83_16745	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CEW83_16750	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CEW83_16775	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CEW83_16780	COG1522	sequence-specific DNA binding
CEW83_16810	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CEW83_16815	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CEW83_16820	COG0018	arginyl-trna synthetase
CEW83_16830	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CEW83_16835	COG0300	oxidoreductase activity
CEW83_16855	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CEW83_16865	COG3243	poly(R)-hydroxyalkanoic acid synthase
CEW83_16885	COG0288	reversible hydration of carbon dioxide
CEW83_16890	COG0183	Belongs to the thiolase family
CEW83_16895	COG1960	acyl-CoA dehydrogenase activity
CEW83_16930	COG0625	glutathione transferase activity
CEW83_16945	COG5002	protein histidine kinase activity
CEW83_16945	COG5001	Diguanylate cyclase
CEW83_16955	COG1960	acyl-CoA dehydrogenase activity
CEW83_16960	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CEW83_16965	COG1024	Enoyl-CoA hydratase
CEW83_16975	COG0318	PFAM AMP-dependent synthetase and ligase
CEW83_17000	COG1660	Displays ATPase and GTPase activities
CEW83_17015	COG2201	protein-glutamate methylesterase activity
CEW83_17025	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CEW83_17030	COG0840	transmembrane signaling receptor activity
CEW83_17035	COG0835	chemotaxis
CEW83_17040	COG0840	transmembrane signaling receptor activity
CEW83_17045	COG0643	Histidine kinase
CEW83_17045	COG2198	Histidine kinase
CEW83_17065	COG0412	Dienelactone hydrolase
CEW83_17070	COG1611	Belongs to the LOG family
CEW83_17095	COG0410	ABC transporter
CEW83_17125	COG1522	sequence-specific DNA binding
CEW83_17130	COG0189	ligase activity
CEW83_17145	COG0697	spore germination
CEW83_17165	COG0788	formyltetrahydrofolate deformylase activity
CEW83_17170	COG0004	ammonium transporteR
CEW83_17175	COG0347	Belongs to the P(II) protein family
CEW83_17190	COG0606	chelatase, subunit chli
CEW83_17200	COG0439	Biotin carboxylase
CEW83_17205	COG3665	Urea carboxylase-associated protein
CEW83_17215	COG1116	anion transmembrane transporter activity
CEW83_17230	COG2814	Major facilitator Superfamily
CEW83_17280	COG3501	Rhs element vgr protein
CEW83_17375	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CEW83_17420	COG3813	Protein conserved in bacteria
CEW83_17440	COG2329	Antibiotic biosynthesis monooxygenase
CEW83_17465	COG1683	Conserved Protein
CEW83_17470	COG2076	Multidrug Resistance protein
CEW83_17480	COG0583	DNA-binding transcription factor activity
CEW83_17485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEW83_17495	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CEW83_17500	COG3876	Protein conserved in bacteria
CEW83_17515	COG0668	transmembrane transport
CEW83_17535	COG0180	Tryptophanyl-tRNA synthetase
CEW83_17545	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CEW83_17550	COG0726	polysaccharide deacetylase
CEW83_17590	COG1132	(ABC) transporter
CEW83_17600	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CEW83_17615	COG0438	transferase activity, transferring glycosyl groups
CEW83_17620	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CEW83_17635	COG0129	dihydroxy-acid dehydratase activity
CEW83_17670	COG0745	RESPONSE REGULATOR receiver
CEW83_17675	COG2205	protein histidine kinase activity
CEW83_17685	COG1280	lysine exporter protein (LysE YggA)
CEW83_17700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CEW83_17705	COG1970	mechanosensitive ion channel activity
CEW83_17710	COG2860	membrane
CEW83_17720	COG0559	Belongs to the binding-protein-dependent transport system permease family
CEW83_17750	COG1194	a g-specific adenine glycosylase
CEW83_17755	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CEW83_17760	COG3706	GGDEF domain
CEW83_17765	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CEW83_17775	COG1132	(ABC) transporter
CEW83_17780	COG0438	transferase activity, transferring glycosyl groups
CEW83_17790	COG0438	transferase activity, transferring glycosyl groups
CEW83_17795	COG1215	transferase activity, transferring glycosyl groups
CEW83_17800	COG0110	maltose O-acetyltransferase activity
CEW83_17815	COG1368	sulfuric ester hydrolase activity
CEW83_17835	COG0438	transferase activity, transferring glycosyl groups
CEW83_17840	COG0859	PFAM glycosyl transferase family 9
CEW83_17850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CEW83_17855	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CEW83_17855	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CEW83_17865	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CEW83_17870	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CEW83_17880	COG4206	TonB-dependent receptor
CEW83_17885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEW83_17890	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CEW83_17900	COG1648	precorrin-2 dehydrogenase activity
CEW83_17900	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CEW83_17905	COG1797	cobyrinic acid a,c-diamide synthase activity
CEW83_17910	COG1902	pentaerythritol trinitrate reductase activity
CEW83_17915	COG0640	Transcriptional regulator
CEW83_17925	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CEW83_17930	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEW83_17935	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEW83_17940	COG0306	phosphate transporter
CEW83_17960	COG0488	(ABC) transporter
CEW83_17980	COG0004	ammonium transporteR
CEW83_17985	COG2226	methyltransferase
CEW83_18005	COG1652	LysM domain
CEW83_18025	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CEW83_18030	COG0840	transmembrane signaling receptor activity
CEW83_18045	COG1671	Belongs to the UPF0178 family
CEW83_18050	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CEW83_18070	COG1024	Enoyl-CoA hydratase
CEW83_18080	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CEW83_18085	COG0602	queuosine metabolic process
CEW83_18100	COG0823	Involved in the tonB-independent uptake of proteins
CEW83_18110	COG0848	biopolymer transport protein
CEW83_18120	COG0824	Thioesterase
CEW83_18130	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CEW83_18135	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CEW83_18145	COG3300	MHYT domain
CEW83_18145	COG5001	Diguanylate cyclase
CEW83_18150	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CEW83_18175	COG3128	pkhd-type hydroxylase
CEW83_18185	COG4774	siderophore transport
CEW83_18195	COG1136	(ABC) transporter
CEW83_18195	COG0577	efflux transmembrane transporter activity
CEW83_18200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEW83_18245	COG3300	MHYT domain
CEW83_18245	COG5001	Diguanylate cyclase
CEW83_18255	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CEW83_18260	COG3132	Protein of unknown function, DUF480
CEW83_18265	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CEW83_18305	COG2264	protein methyltransferase activity
CEW83_18310	COG0439	Biotin carboxylase
CEW83_18315	COG0511	ligase activity, forming carbon-carbon bonds
CEW83_18320	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CEW83_18325	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEW83_18335	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CEW83_18345	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CEW83_18350	COG0792	nuclease activity
CEW83_18360	COG0418	dihydroorotase activity
CEW83_18375	COG2001	Belongs to the MraZ family
CEW83_18380	COG0275	rRNA processing
CEW83_18395	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CEW83_18400	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CEW83_18405	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CEW83_18410	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CEW83_18415	COG0772	Belongs to the SEDS family
CEW83_18420	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CEW83_18425	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CEW83_18430	COG1181	Belongs to the D-alanine--D-alanine ligase family
CEW83_18435	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CEW83_18450	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CEW83_18465	COG0653	protein targeting
CEW83_18470	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CEW83_18475	COG3158	transport of potassium into the cell
CEW83_18480	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CEW83_18490	COG2967	ApaG domain
CEW83_18505	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CEW83_18510	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CEW83_18515	COG1862	Preprotein translocase
CEW83_18520	COG0343	queuine tRNA-ribosyltransferase activity
CEW83_18525	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CEW83_18535	COG0583	DNA-binding transcription factor activity
CEW83_18545	COG0670	Belongs to the BI1 family
CEW83_18550	COG0825	malonyl-CoA metabolic process
CEW83_18555	COG0037	tRNA processing
CEW83_18585	COG1187	pseudouridine synthase activity
CEW83_18590	COG1253	flavin adenine dinucleotide binding
CEW83_18595	COG0861	Integral membrane protein TerC family
CEW83_18610	COG1136	(ABC) transporter
CEW83_18610	COG0577	efflux transmembrane transporter activity
CEW83_18615	COG0577	efflux transmembrane transporter activity
CEW83_18615	COG1136	(ABC) transporter
CEW83_18620	COG1136	(ABC) transporter
CEW83_18620	COG0577	efflux transmembrane transporter activity
CEW83_18630	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CEW83_18635	COG0668	transmembrane transport
CEW83_18640	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CEW83_18645	COG2885	chlorophyll binding
CEW83_18650	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CEW83_18660	COG4647	ligase activity
CEW83_18665	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
CEW83_18670	COG0145	ligase activity
CEW83_18675	COG3284	Transcriptional regulator
CEW83_18680	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CEW83_18685	COG0351	phosphomethylpyrimidine kinase
CEW83_18695	COG0577	efflux transmembrane transporter activity
CEW83_18695	COG1136	(ABC) transporter
CEW83_18720	COG0489	protein tyrosine kinase activity
CEW83_18730	COG3409	Peptidoglycan-binding domain 1 protein
CEW83_18730	COG3267	Type II secretory pathway component ExeA
CEW83_18760	COG0367	asparagine synthase
CEW83_18765	COG0438	transferase activity, transferring glycosyl groups
CEW83_18770	COG0367	asparagine synthase
CEW83_18790	COG0297	glycogen (starch) synthase activity
CEW83_18825	COG2327	Polysaccharide pyruvyl transferase
CEW83_18835	COG0438	transferase activity, transferring glycosyl groups
CEW83_18880	COG0367	asparagine synthase
CEW83_18895	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CEW83_18900	COG0071	Belongs to the small heat shock protein (HSP20) family
CEW83_18925	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CEW83_18935	COG0741	lytic transglycosylase activity
CEW83_18945	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CEW83_18950	COG0280	phosphate acetyltransferase
CEW83_18950	COG0281	malic enzyme
CEW83_18970	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CEW83_18970	COG2111	Na H antiporter
CEW83_18975	COG1006	Multisubunit Na H antiporter MnhC subunit
CEW83_18980	COG0651	ATP synthesis coupled electron transport
CEW83_18985	COG1863	multisubunit Na H antiporter MnhE subunit
CEW83_18990	COG2212	antiporter activity
CEW83_18995	COG1320	monovalent cation:proton antiporter activity
CEW83_19000	COG1320	monovalent cation:proton antiporter activity
CEW83_19005	COG2212	antiporter activity
CEW83_19025	COG2111	Na H antiporter
CEW83_19025	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CEW83_19030	COG0105	UTP biosynthetic process
CEW83_19035	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CEW83_19050	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CEW83_19055	COG0124	histidyl-tRNA synthetase
CEW83_19060	COG2976	Protein conserved in bacteria
CEW83_19070	COG1160	GTP binding
CEW83_19075	COG1923	regulation of RNA biosynthetic process
CEW83_19080	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CEW83_19085	COG0330	HflC and HflK could
CEW83_19090	COG0330	HflC and HflK could
CEW83_19100	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CEW83_19105	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CEW83_19125	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CEW83_19130	COG3707	response regulator
CEW83_19135	COG1116	anion transmembrane transporter activity
CEW83_19135	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CEW83_19140	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CEW83_19145	COG1116	anion transmembrane transporter activity
CEW83_19155	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CEW83_19160	COG2146	nitrite reductase [NAD(P)H] activity
CEW83_19170	COG0517	IMP dehydrogenase activity
CEW83_19175	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CEW83_19205	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CEW83_19210	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CEW83_19215	COG0723	plastoquinol--plastocyanin reductase activity
CEW83_19220	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CEW83_19225	COG2857	Cytochrome c1
CEW83_19230	COG0625	glutathione transferase activity
CEW83_19235	COG2969	positive regulation of protein catabolic process
CEW83_19240	COG0438	transferase activity, transferring glycosyl groups
CEW83_19250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CEW83_19255	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CEW83_19265	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CEW83_19270	COG0459	protein refolding
CEW83_19275	COG0745	RESPONSE REGULATOR receiver
CEW83_19280	COG0642	Histidine kinase
CEW83_19285	COG3162	membrane
CEW83_19295	COG0642	Histidine kinase
CEW83_19310	COG3046	protein related to deoxyribodipyrimidine photolyase
CEW83_19315	COG0415	Belongs to the DNA photolyase family
CEW83_19330	COG2902	Dehydrogenase
CEW83_19335	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CEW83_19340	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CEW83_19345	COG2890	protein-(glutamine-N5) methyltransferase activity
CEW83_19350	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CEW83_19375	COG2815	serine threonine protein kinase
CEW83_19375	COG0515	serine threonine protein kinase
CEW83_19380	COG0165	Argininosuccinate lyase
CEW83_19425	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CEW83_19435	COG0181	hydroxymethylbilane synthase activity
CEW83_19445	COG2959	enzyme of heme biosynthesis
CEW83_19455	COG0659	secondary active sulfate transmembrane transporter activity
CEW83_19460	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEW83_19460	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEW83_19470	COG0489	protein tyrosine kinase activity
CEW83_19475	COG0717	Belongs to the dCTP deaminase family
CEW83_19480	COG1982	Orn Lys Arg decarboxylase major
CEW83_19490	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CEW83_19630	COG3411	Ferredoxin
CEW83_19645	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CEW83_19670	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CEW83_19675	COG0393	Putative heavy-metal-binding
CEW83_19685	COG0217	transcriptional regulatory protein
CEW83_19690	COG0433	COG0433 Predicted ATPase
CEW83_19695	COG0697	spore germination
CEW83_19705	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CEW83_19710	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CEW83_19715	COG3153	acetyltransferase
CEW83_19715	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CEW83_19720	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CEW83_19720	COG3153	acetyltransferase
CEW83_19725	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CEW83_19735	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CEW83_19745	COG1560	Kdo2-lipid A biosynthetic process
CEW83_19755	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CEW83_19775	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CEW83_19785	COG2255	four-way junction helicase activity
CEW83_19790	COG0632	four-way junction helicase activity
CEW83_19795	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEW83_19805	COG1530	ribonuclease E activity
CEW83_19810	COG0424	maF-like protein
CEW83_19815	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CEW83_19820	COG0799	negative regulation of ribosome biogenesis
CEW83_19825	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CEW83_19840	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CEW83_19865	COG1088	dTDP-glucose 4,6-dehydratase activity
CEW83_19870	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CEW83_19880	COG2089	acid synthase
CEW83_19885	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CEW83_19890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CEW83_19890	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CEW83_19900	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CEW83_19910	COG1083	cytidylyl-transferase
CEW83_19920	COG2192	nodulation
CEW83_19925	COG1028	Short-chain dehydrogenase reductase Sdr
CEW83_19935	COG2226	methyltransferase
CEW83_19950	COG0110	maltose O-acetyltransferase activity
CEW83_19960	COG1215	transferase activity, transferring glycosyl groups
CEW83_19965	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CEW83_19970	COG1215	transferase activity, transferring glycosyl groups
CEW83_19975	COG1216	Glycosyl transferase, family 2
CEW83_19980	COG0438	transferase activity, transferring glycosyl groups
CEW83_19985	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CEW83_19995	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CEW83_20005	COG2192	nodulation
CEW83_20020	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CEW83_20025	COG2233	PERMEase
CEW83_20045	COG0708	Exodeoxyribonuclease III
CEW83_20050	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CEW83_20060	COG0243	molybdopterin cofactor binding
CEW83_20075	COG0251	oxidation-reduction process
CEW83_20080	COG1238	metal cluster binding
CEW83_20095	COG0037	tRNA processing
CEW83_20100	COG1028	Short-chain dehydrogenase reductase Sdr
CEW83_20120	COG0625	glutathione transferase activity
CEW83_20130	COG0617	tRNA 3'-terminal CCA addition
CEW83_20145	COG0741	lytic transglycosylase activity
CEW83_20150	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CEW83_20155	COG5002	protein histidine kinase activity
CEW83_20155	COG3447	MASE1 domain protein
CEW83_20155	COG5001	Diguanylate cyclase
CEW83_20165	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CEW83_20170	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CEW83_20180	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CEW83_20185	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CEW83_20195	COG2137	regulation of response to DNA damage stimulus
CEW83_20200	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CEW83_20205	COG1546	Belongs to the CinA family
CEW83_20210	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CEW83_20215	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CEW83_20220	COG5001	Diguanylate cyclase
CEW83_20220	COG3300	MHYT domain
CEW83_20235	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CEW83_20245	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CEW83_20250	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CEW83_20255	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CEW83_20270	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CEW83_20275	COG4974	Belongs to the 'phage' integrase family
CEW83_20280	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CEW83_20285	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CEW83_20290	COG1466	dna polymerase III delta subunit
CEW83_20300	COG0495	leucyl-tRNA aminoacylation
CEW83_20310	COG0210	DNA helicase
CEW83_20315	COG1192	Involved in chromosome partitioning
CEW83_20320	COG0280	phosphate acetyltransferase
CEW83_20320	COG0281	malic enzyme
CEW83_20335	COG0668	transmembrane transport
CEW83_20345	COG0408	coproporphyrinogen oxidase activity
CEW83_20350	COG3422	double-strand break repair
CEW83_20355	COG0151	Belongs to the GarS family
CEW83_20360	COG0138	bifunctional purine biosynthesis protein purh
CEW83_20365	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CEW83_20375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CEW83_20380	COG0006	proline dipeptidase activity
CEW83_20395	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CEW83_20400	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CEW83_20405	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CEW83_20410	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CEW83_20430	COG0004	ammonium transporteR
CEW83_20455	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CEW83_20470	COG2353	YceI-like domain
CEW83_20480	COG3038	cytochrome b561
CEW83_20485	COG3384	dioxygenase
CEW83_20495	COG3437	response regulator, receiver
CEW83_20500	COG2198	Histidine kinase
CEW83_20500	COG2205	protein histidine kinase activity
CEW83_20500	COG0784	Response regulator, receiver
CEW83_20510	COG2828	Protein conserved in bacteria
CEW83_20515	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CEW83_20530	COG0191	fructose-bisphosphate aldolase activity
CEW83_20535	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CEW83_20545	COG3954	Phosphoribulokinase
CEW83_20550	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CEW83_20560	COG4451	ribulose bisphosphate carboxylase, small
CEW83_20575	COG3706	GGDEF domain
CEW83_20575	COG0745	RESPONSE REGULATOR receiver
CEW83_20590	COG0469	pyruvate kinase activity
CEW83_20600	COG0126	phosphoglycerate kinase activity
CEW83_20610	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CEW83_20615	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CEW83_20620	COG3954	Phosphoribulokinase
CEW83_20630	COG0483	inositol monophosphate 1-phosphatase activity
CEW83_20635	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CEW83_20645	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CEW83_20645	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CEW83_20655	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CEW83_20660	COG0704	Plays a role in the regulation of phosphate uptake
CEW83_20665	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CEW83_20670	COG0303	'Molybdopterin
CEW83_20675	COG2833	Protein of unknown function (DUF455)
CEW83_20685	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CEW83_20700	COG2226	methyltransferase
CEW83_20705	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CEW83_20710	COG1040	competence protein
CEW83_20715	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CEW83_20720	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CEW83_20730	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CEW83_20740	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CEW83_20745	COG0640	Transcriptional regulator
CEW83_20750	COG0588	phosphoglycerate mutase activity
CEW83_20760	COG0793	Belongs to the peptidase S41A family
CEW83_20775	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CEW83_20775	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CEW83_20780	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CEW83_20785	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CEW83_20805	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CEW83_20810	COG4651	solute:proton antiporter activity
CEW83_20810	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CEW83_20820	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CEW83_20830	COG0402	S-adenosylhomocysteine deaminase activity
CEW83_20835	COG0515	serine threonine protein kinase
CEW83_20835	COG2815	serine threonine protein kinase
CEW83_20840	COG1950	PFAM Membrane protein of
CEW83_20845	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CEW83_20850	COG1420	regulation of RNA biosynthetic process
CEW83_20855	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CEW83_20860	COG0497	DNA recombination
CEW83_20865	COG0735	belongs to the Fur family
CEW83_20870	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CEW83_20875	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CEW83_20885	COG0505	Belongs to the CarA family
CEW83_20895	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CEW83_20905	COG1534	Rna-binding protein
CEW83_20910	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit