locus-tag	class	description
dqs_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
dqs_0006	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
dqs_0021	COG1028	Short-chain dehydrogenase reductase Sdr
dqs_0022	COG0583	DNA-binding transcription factor activity
dqs_0023	COG0564	pseudouridine synthase activity
dqs_0028	COG0693	protein deglycase activity
dqs_0033	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
dqs_0033	COG3608	succinylglutamate desuccinylase aspartoacylase
dqs_0035	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
dqs_0036	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
dqs_0037	COG1216	Glycosyl transferase, family 2
dqs_0039	COG1253	flavin adenine dinucleotide binding
dqs_0040	COG0583	DNA-binding transcription factor activity
dqs_0041	COG0477	Major facilitator Superfamily
dqs_0049	COG1944	ATP diphosphatase activity
dqs_0050	COG4977	sequence-specific DNA binding
dqs_0050	COG1917	Cupin 2, conserved barrel domain protein
dqs_0053	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
dqs_0054	COG1984	allophanate hydrolase subunit 2
dqs_0055	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
dqs_0056	COG0596	Alpha beta hydrolase
dqs_0057	COG4676	Protein conserved in bacteria
dqs_0058	COG4676	Protein conserved in bacteria
dqs_0059	COG5445	Predicted secreted protein (DUF2300)
dqs_0065	COG1136	(ABC) transporter
dqs_0066	COG0577	efflux transmembrane transporter activity
dqs_0069	COG2373	Large extracellular alpha-helical protein
dqs_0071	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
dqs_0074	COG0628	permease
dqs_0076	COG1024	Enoyl-CoA hydratase
dqs_0082	COG4191	Histidine kinase
dqs_0084	COG2304	oxidoreductase activity
dqs_0085	COG1595	DNA-templated transcription, initiation
dqs_0089	COG1690	Belongs to the RtcB family
dqs_0090	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
dqs_0092	COG2974	May be involved in recombination
dqs_0094	COG1187	pseudouridine synthase activity
dqs_0096	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
dqs_0098	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
dqs_0100	COG3909	cytochrome
dqs_0101	COG0840	transmembrane signaling receptor activity
dqs_0102	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
dqs_0103	COG4206	TonB-dependent receptor
dqs_0105	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
dqs_0105	COG0551	DNA topoisomerase type I activity
dqs_0106	COG2922	Belongs to the Smg family
dqs_0107	COG0758	DNA mediated transformation
dqs_0109	COG0242	peptide deformylase activity
dqs_0110	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
dqs_0112	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
dqs_0113	COG1305	Transglutaminase-like
dqs_0119	COG1490	D-aminoacyl-tRNA deacylase activity
dqs_0120	COG1741	Belongs to the pirin family
dqs_0122	COG0583	DNA-binding transcription factor activity
dqs_0123	COG0625	glutathione transferase activity
dqs_0125	COG2030	dehydratase
dqs_0126	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
dqs_0132	COG0820	rRNA (adenine-C2-)-methyltransferase activity
dqs_0138	COG0840	transmembrane signaling receptor activity
dqs_0139	COG0840	transmembrane signaling receptor activity
dqs_0140	COG1942	4-Oxalocrotonate Tautomerase
dqs_0141	COG0583	DNA-binding transcription factor activity
dqs_0143	COG3706	GGDEF domain
dqs_0150	COG0445	tRNA wobble uridine modification
dqs_0151	COG0357	Ribosomal RNA small subunit methyltransferase G
dqs_0152	COG1192	Involved in chromosome partitioning
dqs_0155	COG1475	DNA binding
dqs_0157	COG0477	Major facilitator Superfamily
dqs_0158	COG0418	dihydroorotase activity
dqs_0160	COG0640	Transcriptional regulator
dqs_0162	COG0356	it plays a direct role in the translocation of protons across the membrane
dqs_0164	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
dqs_0165	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
dqs_0166	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
dqs_0167	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
dqs_0168	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
dqs_0169	COG0355	proton-transporting ATP synthase activity, rotational mechanism
dqs_0171	COG2226	methyltransferase
dqs_0173	COG0745	RESPONSE REGULATOR receiver
dqs_0177	COG0121	glutamine amidotransferase
dqs_0179	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
dqs_0181	COG0154	amidase activity
dqs_0182	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
dqs_0183	COG1077	Cell shape determining protein MreB Mrl
dqs_0186	COG0768	penicillin binding
dqs_0187	COG0772	Belongs to the SEDS family
dqs_0189	COG1686	Belongs to the peptidase S11 family
dqs_0191	COG2921	Belongs to the UPF0250 family
dqs_0192	COG0321	lipoyl(octanoyl) transferase activity
dqs_0193	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
dqs_0203	COG1028	Short-chain dehydrogenase reductase Sdr
dqs_0206	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
dqs_0212	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
dqs_0212	COG0512	Glutamine amidotransferase of anthranilate synthase
dqs_0214	COG0419	ATPase involved in DNA repair
dqs_0219	COG1473	amidohydrolase
dqs_0220	COG2207	Transcriptional regulator
dqs_0226	COG1522	sequence-specific DNA binding
dqs_0231	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
dqs_0233	COG0601	transmembrane transport
dqs_0234	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
dqs_0250	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
dqs_0251	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
dqs_0254	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
dqs_0259	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
dqs_0261	COG2193	ferroxidase activity
dqs_0273	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
dqs_0276	COG0642	Histidine kinase
dqs_0286	COG1595	DNA-templated transcription, initiation
dqs_0294	COG1360	Flagellar Motor Protein
dqs_0298	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
dqs_0302	COG1131	(ABC) transporter
dqs_0305	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
dqs_0309	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
dqs_0311	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
dqs_0313	COG1024	Enoyl-CoA hydratase
dqs_0314	COG1250	3-hydroxyacyl-CoA dehydrogenase
dqs_0315	COG2050	protein possibly involved in aromatic compounds catabolism
dqs_0317	COG3396	Phenylacetate-CoA oxygenase
dqs_0318	COG3460	Phenylacetate-CoA oxygenase
dqs_0319	COG3396	Phenylacetate-CoA oxygenase
dqs_0320	COG2151	metal-sulfur cluster biosynthetic enzyme
dqs_0321	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
dqs_0323	COG0183	Belongs to the thiolase family
dqs_0329	COG0513	Belongs to the DEAD box helicase family
dqs_0330	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
dqs_0331	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
dqs_0334	COG4232	protein-disulfide reductase activity
dqs_0335	COG1324	tolerance protein
dqs_0336	COG2070	2-Nitropropane dioxygenase
dqs_0338	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
dqs_0340	COG1309	transcriptional regulator
dqs_0343	COG0583	DNA-binding transcription factor activity
dqs_0348	COG1716	ATPase activity
dqs_0348	COG5001	Diguanylate cyclase
dqs_0349	COG3706	GGDEF domain
dqs_0351	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
dqs_0355	COG1192	Involved in chromosome partitioning
dqs_0358	COG0025	NhaP-type Na H and K H
dqs_0372	COG1131	(ABC) transporter
dqs_0373	COG0625	glutathione transferase activity
dqs_0378	COG1045	serine acetyltransferase
dqs_0380	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
dqs_0381	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
dqs_0382	COG2119	membrane
dqs_0384	COG3154	lipid carrier protein
dqs_0385	COG0826	peptidase U32
dqs_0386	COG0826	peptidase U32
dqs_0387	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
dqs_0388	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
dqs_0389	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
dqs_0392	COG0018	arginyl-trna synthetase
dqs_0394	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
dqs_0395	COG0300	oxidoreductase activity
dqs_0400	COG3243	poly(R)-hydroxyalkanoic acid synthase
dqs_0404	COG0183	Belongs to the thiolase family
dqs_0405	COG1960	acyl-CoA dehydrogenase activity
dqs_0409	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
dqs_0410	COG1660	Displays ATPase and GTPase activities
dqs_0413	COG2201	protein-glutamate methylesterase activity
dqs_0415	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
dqs_0416	COG0835	chemotaxis
dqs_0417	COG0840	transmembrane signaling receptor activity
dqs_0418	COG0643	Histidine kinase
dqs_0418	COG2198	Histidine kinase
dqs_0421	COG0745	RESPONSE REGULATOR receiver
dqs_0424	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
dqs_0425	COG0602	queuosine metabolic process
dqs_0427	COG2885	chlorophyll binding
dqs_0428	COG0823	Involved in the tonB-independent uptake of proteins
dqs_0430	COG0848	biopolymer transport protein
dqs_0431	COG0811	peptide transport
dqs_0432	COG0824	Thioesterase
dqs_0434	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
dqs_0435	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
dqs_0437	COG5001	Diguanylate cyclase
dqs_0437	COG3300	MHYT domain
dqs_0438	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
dqs_0439	COG2895	sulfate adenylyltransferase (ATP) activity
dqs_0440	COG0175	sulfate reduction
dqs_0441	COG0175	sulfate reduction
dqs_0444	COG0730	response to heat
dqs_0445	COG0583	DNA-binding transcription factor activity
dqs_0450	COG1126	abc transporter atp-binding protein
dqs_0451	COG0765	amino acid transport
dqs_0452	COG0765	amino acid transport
dqs_0453	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
dqs_0455	COG1793	dna ligase
dqs_0455	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
dqs_0456	COG1201	RNA secondary structure unwinding
dqs_0459	COG4191	Histidine kinase
dqs_0461	COG5001	Diguanylate cyclase
dqs_0463	COG0492	ferredoxin-NADP+ reductase activity
dqs_0464	COG5265	(ABC) transporter
dqs_0466	COG0523	cobalamin synthesis protein
dqs_0468	COG0745	RESPONSE REGULATOR receiver
dqs_0469	COG5002	protein histidine kinase activity
dqs_0470	COG0004	ammonium transporteR
dqs_0474	COG1960	acyl-CoA dehydrogenase activity
dqs_0476	COG1250	3-hydroxyacyl-CoA dehydrogenase
dqs_0476	COG1024	Enoyl-CoA hydratase
dqs_0478	COG2067	long-chain fatty acid transport protein
dqs_0479	COG1250	3-hydroxyacyl-CoA dehydrogenase
dqs_0479	COG1024	Enoyl-CoA hydratase
dqs_0480	COG0183	Belongs to the thiolase family
dqs_0481	COG1024	Enoyl-CoA hydratase
dqs_0486	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
dqs_0488	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
dqs_0489	COG3161	chorismate lyase activity
dqs_0490	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
dqs_0492	COG0251	oxidation-reduction process
dqs_0493	COG1238	metal cluster binding
dqs_0496	COG0037	tRNA processing
dqs_0501	COG0625	glutathione transferase activity
dqs_0503	COG0617	tRNA 3'-terminal CCA addition
dqs_0506	COG0741	lytic transglycosylase activity
dqs_0507	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
dqs_0510	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
dqs_0511	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
dqs_0513	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
dqs_0514	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
dqs_0516	COG2137	regulation of response to DNA damage stimulus
dqs_0517	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
dqs_0518	COG1546	Belongs to the CinA family
dqs_0519	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
dqs_0520	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
dqs_0521	COG2914	Belongs to the UPF0125 (RnfH) family
dqs_0525	COG4656	Part of a membrane complex involved in electron transport
dqs_0526	COG2878	Part of a membrane complex involved in electron transport
dqs_0527	COG4657	Part of a membrane complex involved in electron transport
dqs_0532	COG2032	superoxide dismutase activity
dqs_0534	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
dqs_0536	COG0426	domain, Protein
dqs_0537	COG0633	Ferredoxin
dqs_0543	COG3647	Membrane
dqs_0548	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
dqs_0552	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
dqs_0555	COG0840	transmembrane signaling receptor activity
dqs_0583	COG3423	Transcriptional regulator
dqs_0618	COG4383	Mu-like prophage protein gp29
dqs_0619	COG2369	cell adhesion
dqs_0641	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
dqs_0642	COG0393	Putative heavy-metal-binding
dqs_0644	COG0217	transcriptional regulatory protein
dqs_0646	COG0433	COG0433 Predicted ATPase
dqs_0647	COG0583	DNA-binding transcription factor activity
dqs_0648	COG2814	Major facilitator Superfamily
dqs_0649	COG0697	spore germination
dqs_0650	COG0840	transmembrane signaling receptor activity
dqs_0651	COG2814	Major facilitator Superfamily
dqs_0652	COG2814	Major facilitator Superfamily
dqs_0654	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
dqs_0655	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
dqs_0656	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
dqs_0658	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
dqs_0660	COG1560	Kdo2-lipid A biosynthetic process
dqs_0662	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
dqs_0664	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
dqs_0666	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
dqs_0669	COG2255	four-way junction helicase activity
dqs_0670	COG0632	four-way junction helicase activity
dqs_0676	COG4774	siderophore transport
dqs_0677	COG3128	pkhd-type hydroxylase
dqs_0680	COG0577	efflux transmembrane transporter activity
dqs_0680	COG1136	(ABC) transporter
dqs_0681	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
dqs_0687	COG4256	Hemin uptake protein
dqs_0691	COG5001	Diguanylate cyclase
dqs_0695	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
dqs_0696	COG3132	Protein of unknown function, DUF480
dqs_0700	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
dqs_0701	COG0129	dihydroxy-acid dehydratase activity
dqs_0703	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
dqs_0707	COG0247	lactate metabolic process
dqs_0711	COG1121	(ABC) transporter
dqs_0713	COG0735	belongs to the Fur family
dqs_0715	COG2274	protein secretion by the type I secretion system
dqs_0716	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
dqs_0717	COG2197	response regulator
dqs_0721	COG3706	GGDEF domain
dqs_0721	COG2203	Gaf domain
dqs_0721	COG5001	Diguanylate cyclase
dqs_0721	COG4251	negative regulation of phosphorylation
dqs_0723	COG1538	Outer membrane efflux protein
dqs_0729	COG1132	(ABC) transporter
dqs_0730	COG1451	nucleotide metabolic process
dqs_0732	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
dqs_0733	COG2267	carboxylic ester hydrolase activity
dqs_0734	COG0671	phosphoesterase, PA-phosphatase related
dqs_0734	COG2453	phosphatase
dqs_0736	COG0204	Acyl-transferase
dqs_0737	COG4589	Belongs to the CDS family
dqs_0738	COG3005	denitrification pathway
dqs_0739	COG3043	anaerobic respiration
dqs_0740	COG0243	molybdopterin cofactor binding
dqs_0742	COG4459	periplasmic nitrate reductase
dqs_0748	COG0583	DNA-binding transcription factor activity
dqs_0749	COG1024	Enoyl-CoA hydratase
dqs_0750	COG3162	membrane
dqs_0751	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
dqs_0752	COG1253	flavin adenine dinucleotide binding
dqs_0753	COG1802	Transcriptional regulator
dqs_0754	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
dqs_0754	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
dqs_0755	COG1703	isobutyryl-CoA mutase activity
dqs_0756	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
dqs_0758	COG4770	biotin carboxylase activity
dqs_0761	COG2321	neutral zinc metallopeptidase
dqs_0766	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
dqs_0766	COG1703	isobutyryl-CoA mutase activity
dqs_0766	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
dqs_0769	COG1262	PFAM Formylglycine-generating sulfatase enzyme
dqs_0771	COG4452	Inner membrane protein CreD
dqs_0772	COG2205	protein histidine kinase activity
dqs_0773	COG0745	RESPONSE REGULATOR receiver
dqs_0774	COG2239	Acts as a magnesium transporter
dqs_0775	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
dqs_0776	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
dqs_0778	COG0557	exoribonuclease II activity
dqs_0780	COG3150	esterase
dqs_0781	COG1968	undecaprenyl-diphosphatase activity
dqs_0785	COG1643	Atp-dependent helicase
dqs_0787	COG0360	Binds together with S18 to 16S ribosomal RNA
dqs_0788	COG2965	DNA replication, synthesis of RNA primer
dqs_0789	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
dqs_0790	COG0359	binds to the 23S rRNA
dqs_0791	COG0305	Participates in initiation and elongation during chromosome replication
dqs_0797	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
dqs_0798	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
dqs_0799	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
dqs_0802	COG0494	nUDIX hydrolase
dqs_0803	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
dqs_0804	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
dqs_0805	COG0237	dephospho-CoA kinase activity
dqs_0807	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
dqs_0808	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
dqs_0808	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
dqs_0810	COG3852	Histidine kinase
dqs_0812	COG0174	glutamine synthetase
dqs_0815	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
dqs_0816	COG3568	Endonuclease Exonuclease Phosphatase
dqs_0817	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
dqs_0818	COG1832	CoA-binding protein
dqs_0819	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
dqs_0823	COG0463	Glycosyl transferase, family 2
dqs_0826	COG0012	GTP binding
dqs_0827	COG0193	aminoacyl-tRNA hydrolase activity
dqs_0828	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
dqs_0829	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
dqs_0831	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
dqs_0832	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
dqs_0834	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
dqs_0835	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
dqs_0836	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
dqs_0837	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
dqs_0838	COG0742	ribosomal rna small subunit methyltransferase
dqs_0839	COG0612	Peptidase, M16
dqs_0840	COG0612	Peptidase, M16
dqs_0842	COG2884	Cell division ATP-binding protein ftsE
dqs_0843	COG2177	Part of the ABC transporter FtsEX involved in
dqs_0845	COG3634	alkyl hydroperoxide reductase activity
dqs_0848	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
dqs_0849	COG1702	phosphate starvation-inducible protein PhoH
dqs_0850	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
dqs_0851	COG4535	Mg2 and Co2 transporter CorC
dqs_0852	COG0815	Transfers the fatty acyl group on membrane lipoproteins
dqs_0855	COG0752	glycyl-tRNA synthetase alpha subunit
dqs_0856	COG0751	glycine-tRNA ligase activity
dqs_0857	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
dqs_0858	COG0204	Acyl-transferase
dqs_0860	COG1024	Enoyl-CoA hydratase
dqs_0861	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
dqs_0863	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
dqs_0873	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
dqs_0875	COG1450	Type ii and iii secretion system protein
dqs_0876	COG1127	ABC transporter
dqs_0877	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
dqs_0878	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
dqs_0879	COG2853	Lipoprotein
dqs_0882	COG1131	(ABC) transporter
dqs_0883	COG0842	Transport permease protein
dqs_0885	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
dqs_0886	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
dqs_0887	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
dqs_0888	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
dqs_0889	COG0436	Aminotransferase
dqs_0890	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
dqs_0891	COG0280	phosphate acetyltransferase
dqs_0891	COG0281	malic enzyme
dqs_0893	COG1686	Belongs to the peptidase S11 family
dqs_0896	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
dqs_0898	COG1187	pseudouridine synthase activity
dqs_0899	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
dqs_0903	COG0577	efflux transmembrane transporter activity
dqs_0903	COG1136	(ABC) transporter
dqs_0904	COG0577	efflux transmembrane transporter activity
dqs_0904	COG1136	(ABC) transporter
dqs_0905	COG1136	(ABC) transporter
dqs_0905	COG0577	efflux transmembrane transporter activity
dqs_0907	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
dqs_0908	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
dqs_0909	COG2885	chlorophyll binding
dqs_0910	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
dqs_0911	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
dqs_0912	COG0351	phosphomethylpyrimidine kinase
dqs_0919	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
dqs_0920	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
dqs_0920	COG0425	Belongs to the sulfur carrier protein TusA family
dqs_0924	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
dqs_0928	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
dqs_0932	COG2264	protein methyltransferase activity
dqs_0933	COG0439	Biotin carboxylase
dqs_0935	COG0511	ligase activity, forming carbon-carbon bonds
dqs_0936	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
dqs_0937	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
dqs_0939	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
dqs_0940	COG2823	Periplasmic or secreted lipoprotein
dqs_0941	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
dqs_0942	COG0792	nuclease activity
dqs_0944	COG0418	dihydroorotase activity
dqs_0946	COG2001	Belongs to the MraZ family
dqs_0947	COG0275	rRNA processing
dqs_0950	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
dqs_0951	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
dqs_0952	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
dqs_0953	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
dqs_0954	COG0772	Belongs to the SEDS family
dqs_0955	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
dqs_0956	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
dqs_0957	COG1181	Belongs to the D-alanine--D-alanine ligase family
dqs_0958	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
dqs_0960	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
dqs_0961	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
dqs_0964	COG0653	protein targeting
dqs_0966	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
dqs_0967	COG0631	protein serine/threonine phosphatase activity
dqs_0971	COG2967	ApaG domain
dqs_0974	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
dqs_0975	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
dqs_0976	COG1862	Preprotein translocase
dqs_0978	COG0343	queuine tRNA-ribosyltransferase activity
dqs_0979	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
dqs_0981	COG0583	DNA-binding transcription factor activity
dqs_0983	COG0670	Belongs to the BI1 family
dqs_0984	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
dqs_0984	COG4651	solute:proton antiporter activity
dqs_0985	COG1253	flavin adenine dinucleotide binding
dqs_0986	COG0861	Integral membrane protein TerC family
dqs_0987	COG0825	malonyl-CoA metabolic process
dqs_0988	COG0037	tRNA processing
dqs_0989	COG4566	intracellular signal transduction
dqs_0994	COG0586	Pfam SNARE associated Golgi protein
dqs_0995	COG0105	UTP biosynthetic process
dqs_0996	COG0820	rRNA (adenine-C2-)-methyltransferase activity
dqs_0999	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
dqs_1000	COG0124	histidyl-tRNA synthetase
dqs_1001	COG2976	Protein conserved in bacteria
dqs_1002	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
dqs_1003	COG1160	GTP binding
dqs_1004	COG1923	regulation of RNA biosynthetic process
dqs_1005	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
dqs_1006	COG0330	HflC and HflK could
dqs_1007	COG0330	HflC and HflK could
dqs_1008	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
dqs_1009	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
dqs_1010	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
dqs_1013	COG0557	exoribonuclease II activity
dqs_1014	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
dqs_1015	COG3707	response regulator
dqs_1016	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
dqs_1018	COG1116	anion transmembrane transporter activity
dqs_1020	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
dqs_1021	COG0243	molybdopterin cofactor binding
dqs_1026	COG0551	DNA topoisomerase type I activity
dqs_1028	COG0716	FMN binding
dqs_1030	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
dqs_1032	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
dqs_1033	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
dqs_1034	COG0723	plastoquinol--plastocyanin reductase activity
dqs_1035	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
dqs_1036	COG2857	Cytochrome c1
dqs_1037	COG0625	glutathione transferase activity
dqs_1039	COG0438	transferase activity, transferring glycosyl groups
dqs_1041	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
dqs_1042	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
dqs_1045	COG4120	Belongs to the binding-protein-dependent transport system permease family
dqs_1047	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
dqs_1048	COG0459	protein refolding
dqs_1050	COG0642	Histidine kinase
dqs_1051	COG3162	membrane
dqs_1081	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
dqs_1082	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
dqs_1084	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
dqs_1089	COG0515	serine threonine protein kinase
dqs_1089	COG2815	serine threonine protein kinase
dqs_1090	COG0165	Argininosuccinate lyase
dqs_1091	COG3275	phosphorelay sensor kinase activity
dqs_1093	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
dqs_1094	COG0181	hydroxymethylbilane synthase activity
dqs_1096	COG2959	enzyme of heme biosynthesis
dqs_1098	COG2186	Transcriptional regulator
dqs_1099	COG0277	FAD linked oxidase domain protein
dqs_1101	COG0277	FAD linked oxidase domain protein
dqs_1102	COG0247	lactate metabolic process
dqs_1103	COG0631	protein serine/threonine phosphatase activity
dqs_1109	COG0513	Belongs to the DEAD box helicase family
dqs_1110	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
dqs_1111	COG0667	Aldo Keto reductase
dqs_1113	COG1653	transport
dqs_1114	COG0584	glycerophosphoryl diester phosphodiesterase
dqs_1115	COG0142	geranyltranstransferase activity
dqs_1117	COG0583	DNA-binding transcription factor activity
dqs_1120	COG0564	pseudouridine synthase activity
dqs_1123	COG3243	poly(R)-hydroxyalkanoic acid synthase
dqs_1124	COG1028	Short-chain dehydrogenase reductase Sdr
dqs_1127	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
dqs_1128	COG1752	Esterase of the alpha-beta hydrolase superfamily
dqs_1129	COG0277	FAD linked oxidase domain protein
dqs_1136	COG1250	3-hydroxyacyl-CoA dehydrogenase
dqs_1137	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
dqs_1141	COG0318	PFAM AMP-dependent synthetase and ligase
dqs_1142	COG0028	Belongs to the TPP enzyme family
dqs_1143	COG0440	acetolactate synthase activity
dqs_1144	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
dqs_1145	COG2814	Major facilitator Superfamily
dqs_1146	COG4783	chaperone-mediated protein folding
dqs_1147	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
dqs_1148	COG0066	3-isopropylmalate dehydratase activity
dqs_1149	COG0473	3-isopropylmalate dehydrogenase activity
dqs_1153	COG0101	tRNA pseudouridine synthase activity
dqs_1154	COG0135	phosphoribosylanthranilate isomerase activity
dqs_1155	COG0133	tryptophan synthase activity
dqs_1156	COG0159	tryptophan synthase activity
dqs_1157	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
dqs_1158	COG0285	dihydrofolate synthase activity
dqs_1159	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
dqs_1163	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
dqs_1164	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
dqs_1165	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
dqs_1168	COG0215	cysteine-tRNA ligase activity
dqs_1170	COG0484	heat shock protein binding
dqs_1171	COG0443	Heat shock 70 kDa protein
dqs_1172	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
dqs_1175	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
dqs_1177	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
dqs_1178	COG0287	Prephenate dehydrogenase
dqs_1179	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
dqs_1181	COG0776	regulation of translation
dqs_1183	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
dqs_1188	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
dqs_1189	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
dqs_1190	COG0291	Belongs to the bacterial ribosomal protein bL35 family
dqs_1191	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
dqs_1192	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
dqs_1193	COG0072	phenylalanine-tRNA ligase activity
dqs_1193	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
dqs_1194	COG0776	regulation of translation
dqs_1197	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
dqs_1198	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
dqs_1200	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
dqs_1201	COG2951	lytic endotransglycosylase activity
dqs_1204	COG0714	Associated with various cellular activities
dqs_1205	COG0123	including yeast histone deacetylase and acetoin utilization protein
dqs_1206	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
dqs_1207	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
dqs_1209	COG2850	peptidyl-arginine hydroxylation
dqs_1210	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
dqs_1215	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
dqs_1219	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
dqs_1221	COG1360	Flagellar Motor Protein
dqs_1222	COG2703	oxygen carrier activity
dqs_1227	COG2860	membrane
dqs_1233	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
dqs_1234	COG4638	Rieske (2fe-2S)
dqs_1238	COG0411	ABC transporter
dqs_1241	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
dqs_1243	COG0542	response to heat
dqs_1244	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
dqs_1245	COG1278	Cold shock
dqs_1246	COG0267	Belongs to the bacterial ribosomal protein bL33 family
dqs_1247	COG0227	Belongs to the bacterial ribosomal protein bL28 family
dqs_1248	COG2003	Belongs to the UPF0758 family
dqs_1249	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
dqs_1250	COG0756	dUTP diphosphatase activity
dqs_1252	COG0446	pyridine nucleotide-disulphide oxidoreductase
dqs_1256	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
dqs_1258	COG0538	isocitrate dehydrogenase activity
dqs_1262	COG1346	cytolysis
dqs_1267	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
dqs_1268	COG0730	response to heat
dqs_1269	COG0583	DNA-binding transcription factor activity
dqs_1271	COG3622	Belongs to the hyi family
dqs_1275	COG1139	Iron-sulfur cluster binding protein
dqs_1277	COG0247	lactate metabolic process
dqs_1288	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
dqs_1290	COG2116	formate transmembrane transporter activity
dqs_1291	COG2815	serine threonine protein kinase
dqs_1291	COG0515	serine threonine protein kinase
dqs_1293	COG4266	Belongs to the allantoicase family
dqs_1299	COG3550	peptidyl-serine autophosphorylation
dqs_1301	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
dqs_1302	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
dqs_1304	COG0535	radical SAM domain protein
dqs_1310	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
dqs_1311	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
dqs_1312	COG1469	GTP cyclohydrolase I activity
dqs_1313	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
dqs_1314	COG0142	geranyltranstransferase activity
dqs_1315	COG1722	exodeoxyribonuclease VII activity
dqs_1317	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
dqs_1318	COG1047	Peptidyl-prolyl cis-trans
dqs_1319	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
dqs_1320	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
dqs_1321	COG0196	riboflavin kinase activity
dqs_1323	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
dqs_1330	COG0803	Belongs to the bacterial solute-binding protein 9 family
dqs_1331	COG1121	(ABC) transporter
dqs_1332	COG1321	iron dependent repressor
dqs_1332	COG1108	ABC-type Mn2 Zn2 transport systems permease components
dqs_1333	COG1108	ABC-type Mn2 Zn2 transport systems permease components
dqs_1338	COG0459	protein refolding
dqs_1341	COG0346	lactoylglutathione lyase activity
dqs_1346	COG1294	oxidase, subunit
dqs_1349	COG2204	response regulator
dqs_1350	COG0723	plastoquinol--plastocyanin reductase activity
dqs_1351	COG1132	(ABC) transporter
dqs_1353	COG0644	oxidoreductase
dqs_1355	COG0641	radical SAM
dqs_1358	COG0860	N-Acetylmuramoyl-L-alanine amidase
dqs_1359	COG0802	atpase or kinase
dqs_1361	COG4948	Mandelate Racemase Muconate Lactonizing
dqs_1362	COG0583	DNA-binding transcription factor activity
dqs_1365	COG2900	Belongs to the SlyX family
dqs_1366	COG0826	peptidase U32
dqs_1368	COG2133	pyrroloquinoline quinone binding
dqs_1369	COG5001	Diguanylate cyclase
dqs_1369	COG3300	MHYT domain
dqs_1371	COG0515	serine threonine protein kinase
dqs_1374	COG2195	Cleaves the N-terminal amino acid of tripeptides
dqs_1376	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
dqs_1377	COG1704	LemA family
dqs_1378	COG3360	Dodecin
dqs_1381	COG0484	heat shock protein binding
dqs_1382	COG1607	acyl-coa hydrolase
dqs_1383	COG4628	conserved protein (DUF2132)
dqs_1384	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
dqs_1388	COG1127	ABC transporter
dqs_1389	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
dqs_1390	COG0488	(ABC) transporter
dqs_1391	COG2226	methyltransferase
dqs_1392	COG0386	Belongs to the glutathione peroxidase family
dqs_1394	COG1858	cytochrome C peroxidase
dqs_1396	COG0583	DNA-binding transcription factor activity
dqs_1397	COG1215	transferase activity, transferring glycosyl groups
dqs_1400	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
dqs_1400	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
dqs_1401	COG0509	glycine decarboxylation via glycine cleavage system
dqs_1402	COG0404	The glycine cleavage system catalyzes the degradation of glycine
dqs_1408	COG2223	nitrite transmembrane transporter activity
dqs_1409	COG0515	serine threonine protein kinase
dqs_1409	COG2815	serine threonine protein kinase
dqs_1413	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
dqs_1416	COG0312	modulator of DNA gyrase
dqs_1432	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
dqs_1433	COG2824	Alkylphosphonate utilization operon protein PhnA
dqs_1435	COG0390	transport system, permease component
dqs_1436	COG3842	ATPase activity
dqs_1446	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
dqs_1447	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
dqs_1449	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
dqs_1450	COG0765	amino acid transport
dqs_1451	COG4597	amino acid ABC transporter
dqs_1452	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
dqs_1453	COG0583	DNA-binding transcription factor activity
dqs_1454	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
dqs_1455	COG4208	sulfate ABC transporter
dqs_1456	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
dqs_1458	COG2951	lytic endotransglycosylase activity
dqs_1462	COG3278	Belongs to the heme-copper respiratory oxidase family
dqs_1472	COG3243	poly(R)-hydroxyalkanoic acid synthase
dqs_1473	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
dqs_1474	COG0635	Involved in the biosynthesis of porphyrin-containing compound
dqs_1477	COG2217	Heavy metal translocating P-type atpase
dqs_1478	COG2608	mercury ion transmembrane transporter activity
dqs_1480	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
dqs_1482	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
dqs_1482	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
dqs_1483	COG0347	Belongs to the P(II) protein family
dqs_1484	COG2840	Smr protein MutS2
dqs_1485	COG0492	ferredoxin-NADP+ reductase activity
dqs_1487	COG1674	ftsk spoiiie
dqs_1488	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
dqs_1489	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
dqs_1491	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
dqs_1492	COG0840	transmembrane signaling receptor activity
dqs_1493	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
dqs_1494	COG0508	dehydrogenase complex catalyzes the overall conversion of
dqs_1495	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
dqs_1498	COG4566	intracellular signal transduction
dqs_1499	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
dqs_1500	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
dqs_1501	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
dqs_1502	COG0009	L-threonylcarbamoyladenylate synthase
dqs_1504	COG0505	Belongs to the CarA family
dqs_1505	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
dqs_1506	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
dqs_1508	COG1534	Rna-binding protein
dqs_1509	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
dqs_1510	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
dqs_1511	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
dqs_1512	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
dqs_1513	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
dqs_1514	COG0573	inorganic phosphate transmembrane transporter activity
dqs_1515	COG0581	inorganic phosphate transmembrane transporter activity
dqs_1517	COG0149	triose-phosphate isomerase activity
dqs_1520	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
dqs_1521	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
dqs_1522	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
dqs_1523	COG0649	NAD binding
dqs_1524	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
dqs_1526	COG1034	ATP synthesis coupled electron transport
dqs_1527	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
dqs_1528	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
dqs_1530	COG0713	ATP synthesis coupled electron transport
dqs_1533	COG1007	ATP synthesis coupled electron transport
dqs_1535	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
dqs_1536	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
dqs_1538	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
dqs_1539	COG3259	Nickel-dependent hydrogenase
dqs_1542	COG1230	cation diffusion facilitator family transporter
dqs_1549	COG0326	Molecular chaperone. Has ATPase activity
dqs_1552	COG0426	domain, Protein
dqs_1552	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
dqs_1559	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
dqs_1560	COG4660	Part of a membrane complex involved in electron transport
dqs_1562	COG4658	electron transport chain
dqs_1563	COG4656	Part of a membrane complex involved in electron transport
dqs_1564	COG2878	Part of a membrane complex involved in electron transport
dqs_1572	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
dqs_1573	COG1360	Flagellar Motor Protein
dqs_1575	COG2198	Histidine kinase
dqs_1575	COG0643	Histidine kinase
dqs_1577	COG0840	transmembrane signaling receptor activity
dqs_1579	COG2201	protein-glutamate methylesterase activity
dqs_1581	COG0784	Response regulator, receiver
dqs_1581	COG0835	chemotaxis
dqs_1582	COG0835	chemotaxis
dqs_1582	COG0784	Response regulator, receiver
dqs_1583	COG0745	RESPONSE REGULATOR receiver
dqs_1584	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
dqs_1585	COG0643	Histidine kinase
dqs_1585	COG0784	Response regulator, receiver
dqs_1585	COG2198	Histidine kinase
dqs_1587	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
dqs_1589	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
dqs_1590	COG1570	exodeoxyribonuclease VII activity
dqs_1591	COG0811	peptide transport
dqs_1592	COG0848	biopolymer transport protein
dqs_1593	COG1663	tetraacyldisaccharide 4'-kinase activity
dqs_1594	COG2835	tetraacyldisaccharide 4'-kinase activity
dqs_1595	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
dqs_1596	COG0563	adenylate kinase activity
dqs_1599	COG5002	protein histidine kinase activity
dqs_1599	COG5001	Diguanylate cyclase
dqs_1600	COG2249	NAD(P)H dehydrogenase (quinone) activity
dqs_1602	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
dqs_1605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
dqs_1605	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
dqs_1606	COG1525	nuclease
dqs_1606	COG4085	toxin activity
dqs_1606	COG0737	Belongs to the 5'-nucleotidase family
dqs_1609	COG2200	EAL domain
dqs_1609	COG3287	FIST C domain
dqs_1609	COG2199	diguanylate cyclase activity
dqs_1610	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
dqs_1612	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
dqs_1616	COG0501	Belongs to the peptidase M48B family
dqs_1617	COG1196	nuclear chromosome segregation
dqs_1620	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
dqs_1627	COG4585	Histidine kinase
dqs_1630	COG1032	radical SAM domain protein
dqs_1633	COG1136	(ABC) transporter
dqs_1636	COG2267	carboxylic ester hydrolase activity
dqs_1637	COG2308	Evidence 4 Homologs of previously reported genes of
dqs_1640	COG0501	Belongs to the peptidase M48B family
dqs_1641	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
dqs_1642	COG0166	Belongs to the GPI family
dqs_1644	COG0254	rRNA binding
dqs_1648	COG0727	PFAM Uncharacterised protein family (UPF0153)
dqs_1649	COG0727	PFAM Uncharacterised protein family (UPF0153)
dqs_1655	COG3012	SEC-C Motif Domain Protein
dqs_1656	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
dqs_1662	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
dqs_1663	COG0022	dehydrogenase e1 component
dqs_1663	COG0508	dehydrogenase complex catalyzes the overall conversion of
dqs_1665	COG2814	Major facilitator Superfamily
dqs_1670	COG0039	L-malate dehydrogenase activity
dqs_1671	COG2188	Transcriptional regulator
dqs_1674	COG1053	succinate dehydrogenase
dqs_1675	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
dqs_1676	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
dqs_1677	COG0372	Belongs to the citrate synthase family
dqs_1678	COG0567	Dehydrogenase, E1 component
dqs_1679	COG0508	dehydrogenase complex catalyzes the overall conversion of
dqs_1680	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
dqs_1682	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
dqs_1683	COG1199	ATP-dependent helicase activity
dqs_1684	COG1763	Mo-molybdopterin cofactor biosynthetic process
dqs_1685	COG0303	'Molybdopterin
dqs_1686	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
dqs_1687	COG0314	molybdopterin synthase activity
dqs_1689	COG0542	response to heat
dqs_1691	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
dqs_1693	COG3781	membrane
dqs_1694	COG0747	negative chemotaxis
dqs_1695	COG0601	transmembrane transport
dqs_1696	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
dqs_1697	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
dqs_1699	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
dqs_1700	COG2867	negative regulation of translational initiation
dqs_1701	COG2914	Belongs to the UPF0125 (RnfH) family
dqs_1704	COG0519	Catalyzes the synthesis of GMP from XMP
dqs_1704	COG0518	GMP synthase (glutamine-hydrolyzing) activity
dqs_1705	COG0583	DNA-binding transcription factor activity
dqs_1710	COG5002	protein histidine kinase activity
dqs_1712	COG1376	ErfK ybiS ycfS ynhG family protein
dqs_1717	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
dqs_1718	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
dqs_1721	COG0084	hydrolase, TatD family'
dqs_1725	COG1305	Transglutaminase-like
dqs_1726	COG2308	Evidence 4 Homologs of previously reported genes of
dqs_1726	COG2307	Protein conserved in bacteria
dqs_1728	COG1473	amidohydrolase
dqs_1729	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
dqs_1730	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
dqs_1732	COG1067	ATP-dependent peptidase activity
dqs_1736	COG0556	nucleotide-excision repair
dqs_1737	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
dqs_1738	COG1530	ribonuclease E activity
dqs_1739	COG0564	pseudouridine synthase activity
dqs_1740	COG0546	phosphoglycolate phosphatase activity
dqs_1742	COG0616	signal peptide processing
dqs_1743	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
dqs_1744	COG0424	maF-like protein
dqs_1745	COG1399	metal-binding, possibly nucleic acid-binding protein
dqs_1746	COG0333	Belongs to the bacterial ribosomal protein bL32 family
dqs_1747	COG0416	fatty acid biosynthetic process
dqs_1748	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
dqs_1749	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
dqs_1751	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
dqs_1752	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
dqs_1754	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
dqs_1759	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
dqs_1761	COG0583	DNA-binding transcription factor activity
dqs_1763	COG3181	Tripartite tricarboxylate transporter family receptor
dqs_1764	COG0481	GTPase activity
dqs_1765	COG0681	Belongs to the peptidase S26 family
dqs_1767	COG0571	ribonuclease III activity
dqs_1768	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
dqs_1769	COG1381	Involved in DNA repair and RecF pathway recombination
dqs_1770	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
dqs_1771	COG0736	holo-[acyl-carrier-protein] synthase activity
dqs_1772	COG1472	Belongs to the glycosyl hydrolase 3 family
dqs_1773	COG0322	excinuclease ABC activity
dqs_1774	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
dqs_1804	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
dqs_1806	COG0850	regulation of cytokinetic process
dqs_1807	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
dqs_1808	COG1393	Belongs to the ArsC family
dqs_1809	COG2183	response to ionizing radiation
dqs_1812	COG3852	Histidine kinase
dqs_1814	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
dqs_1817	COG4181	ATPase activity
dqs_1818	COG0560	Phosphoserine phosphatase
dqs_1819	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
dqs_1822	COG0598	Magnesium transport protein CorA
dqs_1823	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
dqs_1829	COG2078	PFAM AMMECR1 domain protein
dqs_1830	COG1355	regulation of microtubule-based process
dqs_1831	COG3174	membrane
dqs_1832	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
dqs_1833	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
dqs_1838	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
dqs_1839	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
dqs_1840	COG0248	Ppx GppA phosphatase
dqs_1841	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
dqs_1842	COG1127	ABC transporter
dqs_1843	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
dqs_1843	COG3218	ABC-type transport auxiliary lipoprotein component
dqs_1845	COG0318	PFAM AMP-dependent synthetase and ligase
dqs_1847	COG0084	hydrolase, TatD family'
dqs_1848	COG1309	transcriptional regulator
dqs_1852	COG1960	acyl-CoA dehydrogenase activity
dqs_1853	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
dqs_1855	COG2350	Protein conserved in bacteria
dqs_1856	COG2917	probably involved in intracellular septation
dqs_1862	COG0456	acetyltransferase
dqs_1863	COG1573	uracil-dna glycosylase
dqs_1864	COG0477	Major facilitator Superfamily
dqs_1865	COG0583	DNA-binding transcription factor activity
dqs_1873	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
dqs_1875	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
dqs_1876	COG0366	Alpha amylase catalytic
dqs_1877	COG0366	Alpha amylase catalytic
dqs_1878	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
dqs_1882	COG1028	Short-chain dehydrogenase reductase Sdr
dqs_1889	COG1028	Short-chain dehydrogenase reductase Sdr
dqs_1890	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
dqs_1895	COG0189	ligase activity
dqs_1903	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
dqs_1906	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
dqs_1906	COG2010	Cytochrome c
dqs_1907	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
dqs_1912	COG0628	permease
dqs_1913	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
dqs_1915	COG5487	UPF0391 membrane protein
dqs_1916	COG1252	NADH dehydrogenase
dqs_1921	COG1271	oxidase subunit
dqs_1922	COG1294	oxidase, subunit
dqs_1927	COG3023	N-Acetylmuramoyl-L-alanine amidase
dqs_1932	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
dqs_1935	COG0671	phosphoesterase, PA-phosphatase related
dqs_1937	COG0438	transferase activity, transferring glycosyl groups
dqs_1939	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
dqs_1945	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
dqs_1946	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
dqs_1947	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
dqs_1948	COG1640	4-alpha-glucanotransferase
dqs_1950	COG0297	glycogen (starch) synthase activity
dqs_1951	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
dqs_1954	COG2192	nodulation
dqs_1955	COG0859	PFAM glycosyl transferase family 9
dqs_1956	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
dqs_1958	COG0297	glycogen (starch) synthase activity
dqs_1960	COG2323	membrane
dqs_1961	COG2204	response regulator
dqs_1966	COG2205	protein histidine kinase activity
dqs_1967	COG1295	ribonuclease BN
dqs_1970	COG5265	(ABC) transporter
dqs_1972	COG1285	pathogenesis
dqs_1973	COG1546	Belongs to the CinA family
dqs_1973	COG1058	Belongs to the CinA family
dqs_1977	COG1017	nitric oxide dioxygenase activity
dqs_1977	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
dqs_1979	COG4771	TonB-dependent receptor
dqs_1984	COG1252	NADH dehydrogenase
dqs_1991	COG0840	transmembrane signaling receptor activity
dqs_2009	COG4569	acetaldehyde dehydrogenase (acetylating) activity
dqs_2010	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
dqs_2023	COG0564	pseudouridine synthase activity
dqs_2030	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
dqs_2031	COG1091	dTDP-4-dehydrorhamnose reductase activity
dqs_2034	COG3447	MASE1 domain protein
dqs_2034	COG5001	Diguanylate cyclase
dqs_2034	COG5002	protein histidine kinase activity
dqs_2037	COG4181	ATPase activity
dqs_2040	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
dqs_2041	COG2866	Carboxypeptidase
dqs_2042	COG3022	response to hydroperoxide
dqs_2044	COG0156	8-amino-7-oxononanoate synthase activity
dqs_2045	COG2267	carboxylic ester hydrolase activity
dqs_2046	COG2226	methyltransferase
dqs_2047	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
dqs_2048	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
dqs_2050	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
dqs_2051	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
dqs_2052	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
dqs_2053	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
dqs_2054	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
dqs_2058	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
dqs_2059	COG0575	Belongs to the CDS family
dqs_2060	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
dqs_2061	COG0233	cytoplasmic translational termination
dqs_2062	COG0528	UMP kinase activity
dqs_2063	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
dqs_2064	COG0052	Belongs to the universal ribosomal protein uS2 family
dqs_2066	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
dqs_2068	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
dqs_2069	COG2204	response regulator
dqs_2070	COG4191	Histidine kinase
dqs_2073	COG2358	TRAP transporter, solute receptor (TAXI family
dqs_2074	COG0579	oxidoreductase
dqs_2078	COG1804	L-carnitine dehydratase bile acid-inducible protein F
dqs_2079	COG1960	acyl-CoA dehydrogenase activity
dqs_2080	COG0583	DNA-binding transcription factor activity
dqs_2082	COG1024	Enoyl-CoA hydratase
dqs_2085	COG1960	acyl-CoA dehydrogenase activity
dqs_2086	COG1960	acyl-CoA dehydrogenase activity
dqs_2087	COG1024	Enoyl-CoA hydratase
dqs_2090	COG1846	Transcriptional regulator
dqs_2092	COG1028	Short-chain dehydrogenase reductase Sdr
dqs_2094	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
dqs_2095	COG2354	Protein conserved in bacteria
dqs_2098	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
dqs_2099	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
dqs_2101	COG0243	molybdopterin cofactor binding
dqs_2102	COG0437	4 iron, 4 sulfur cluster binding
dqs_2115	COG0633	Ferredoxin
dqs_2115	COG0543	2 iron, 2 sulfur cluster binding
dqs_2117	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
dqs_2119	COG2207	Transcriptional regulator
dqs_2124	COG1802	Transcriptional regulator
dqs_2126	COG1063	alcohol dehydrogenase
dqs_2127	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
dqs_2128	COG4569	acetaldehyde dehydrogenase (acetylating) activity
dqs_2129	COG3971	2-oxopent-4-enoate hydratase activity
dqs_2130	COG3384	dioxygenase
dqs_2131	COG0596	Alpha beta hydrolase
dqs_2131	COG0508	dehydrogenase complex catalyzes the overall conversion of
dqs_2134	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
dqs_2139	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
dqs_2140	COG0318	PFAM AMP-dependent synthetase and ligase
dqs_2143	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
dqs_2149	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
dqs_2155	COG1210	Utp--glucose-1-phosphate uridylyltransferase
dqs_2156	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
dqs_2158	COG1196	nuclear chromosome segregation
dqs_2159	COG0436	Aminotransferase
dqs_2160	COG2171	N-acyltransferase activity
dqs_2162	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
dqs_2164	COG0784	Response regulator, receiver
dqs_2166	COG0633	Ferredoxin
dqs_2167	COG0443	Heat shock 70 kDa protein
dqs_2168	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
dqs_2170	COG0822	iron-sulfur transferase activity
dqs_2171	COG1104	cysteine desulfurase activity
dqs_2172	COG1104	cysteine desulfurase activity
dqs_2174	COG1045	serine acetyltransferase
dqs_2176	COG0483	inositol monophosphate 1-phosphatase activity
dqs_2178	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
dqs_2181	COG0328	RNA-DNA hybrid ribonuclease activity
dqs_2182	COG2226	methyltransferase
dqs_2183	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
dqs_2185	COG2203	Gaf domain
dqs_2185	COG3706	GGDEF domain
dqs_2185	COG4251	negative regulation of phosphorylation
dqs_2185	COG5001	Diguanylate cyclase
dqs_2186	COG1388	LysM domain
dqs_2186	COG0741	lytic transglycosylase activity
dqs_2187	COG4172	Belongs to the ABC transporter superfamily
dqs_2188	COG1047	Peptidyl-prolyl cis-trans
dqs_2189	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
dqs_2190	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
dqs_2192	COG0534	Mate efflux family protein
dqs_2193	COG1393	Belongs to the ArsC family
dqs_2198	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
dqs_2199	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
dqs_2200	COG0740	serine-type endopeptidase activity
dqs_2201	COG0544	peptidyl-prolyl cis-trans isomerase activity
dqs_2202	COG2766	serine protein kinase
dqs_2203	COG2718	Belongs to the UPF0229 family
dqs_2204	COG2719	SpoVR family
dqs_2205	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
dqs_2205	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
dqs_2211	COG0436	Aminotransferase
dqs_2218	COG4968	Prepilin-type N-terminal cleavage methylation domain
dqs_2219	COG4796	Type ii and iii secretion system protein
dqs_2225	COG1459	type II secretion system
dqs_2226	COG2165	general secretion pathway protein
dqs_2227	COG0741	lytic transglycosylase activity
dqs_2227	COG0739	heme binding
dqs_2227	COG1196	nuclear chromosome segregation
dqs_2229	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
dqs_2234	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
dqs_2235	COG1185	polyribonucleotide nucleotidyltransferase activity
dqs_2236	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
dqs_2237	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
dqs_2238	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
dqs_2239	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
dqs_2240	COG2251	uridine kinase activity
dqs_2240	COG0195	Participates in both transcription termination and antitermination
dqs_2241	COG0779	Required for maturation of 30S ribosomal subunits
dqs_2242	COG1187	pseudouridine synthase activity
dqs_2243	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
dqs_2244	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
dqs_2245	COG1994	Peptidase M50
dqs_2246	COG0009	L-threonylcarbamoyladenylate synthase
dqs_2247	COG0613	PHP domain protein
dqs_2251	COG1012	belongs to the aldehyde dehydrogenase family
dqs_2252	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
dqs_2253	COG1278	Cold shock
dqs_2260	COG3706	GGDEF domain
dqs_2262	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
dqs_2264	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
dqs_2265	COG0302	gtp cyclohydrolase
dqs_2267	COG0306	phosphate transporter
dqs_2269	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
dqs_2274	COG0791	NLP P60 protein
dqs_2276	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
dqs_2277	COG0148	phosphopyruvate hydratase activity
dqs_2278	COG2877	3-deoxy-8-phosphooctulonate synthase activity
dqs_2279	COG0504	CTP synthase activity
dqs_2282	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
dqs_2283	COG0824	Thioesterase
dqs_2291	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
dqs_2291	COG0047	phosphoribosylformylglycinamidine synthase activity
dqs_2292	COG0671	phosphoesterase, PA-phosphatase related
dqs_2294	COG0463	Glycosyl transferase, family 2
dqs_2299	COG0739	heme binding
dqs_2301	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
dqs_2303	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
dqs_2304	COG0840	transmembrane signaling receptor activity
dqs_2305	COG0183	Belongs to the thiolase family
dqs_2306	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
dqs_2307	COG0494	nUDIX hydrolase
dqs_2316	COG1666	GTP binding
dqs_2317	COG3123	guanosine phosphorylase activity
dqs_2319	COG0137	argininosuccinate synthase activity
dqs_2320	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
dqs_2321	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
dqs_2323	COG0268	Binds directly to 16S ribosomal RNA
dqs_2328	COG2081	HI0933 family
dqs_2330	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
dqs_2331	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
dqs_2332	COG0840	transmembrane signaling receptor activity
dqs_2336	COG0791	NLP P60 protein
dqs_2338	COG1840	ABC-type Fe3 transport system, periplasmic component
dqs_2339	COG1178	ABC-type Fe3 transport system permease component
dqs_2340	COG3842	ATPase activity
dqs_2341	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
dqs_2342	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
dqs_2343	COG0167	dihydroorotate dehydrogenase activity
dqs_2347	COG3845	ABC transporter
dqs_2348	COG4603	Belongs to the binding-protein-dependent transport system permease family
dqs_2349	COG1079	Belongs to the binding-protein-dependent transport system permease family
dqs_2350	COG4772	TonB-dependent receptor
dqs_2352	COG0310	cobalt ion transport
dqs_2353	COG0310	cobalt ion transport
dqs_2355	COG1122	ATPase activity
dqs_2356	COG0402	S-adenosylhomocysteine deaminase activity
dqs_2357	COG1671	Belongs to the UPF0178 family
dqs_2361	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
dqs_2364	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
dqs_2368	COG0438	transferase activity, transferring glycosyl groups
dqs_2369	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
dqs_2370	COG0438	transferase activity, transferring glycosyl groups
dqs_2373	COG0489	protein tyrosine kinase activity
dqs_2379	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
dqs_2381	COG1012	belongs to the aldehyde dehydrogenase family
dqs_2384	COG2409	Drug exporters of the RND superfamily
dqs_2389	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
dqs_2390	COG2259	Doxx family
dqs_2396	COG0765	amino acid transport
dqs_2397	COG1126	abc transporter atp-binding protein
dqs_2404	COG3158	transport of potassium into the cell
dqs_2405	COG0657	acetylesterase activity
dqs_2406	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
dqs_2407	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
dqs_2408	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
dqs_2411	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
dqs_2415	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
dqs_2416	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
dqs_2420	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
dqs_2423	COG0121	glutamine amidotransferase
dqs_2425	COG2169	Transcriptional regulator
dqs_2425	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
dqs_2429	COG2154	pterin-4-alpha-carbinolamine dehydratase
dqs_2432	COG1960	acyl-CoA dehydrogenase activity
dqs_2435	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
dqs_2440	COG0366	Alpha amylase catalytic
dqs_2443	COG0837	glucose binding
dqs_2446	COG1132	(ABC) transporter
dqs_2452	COG0297	glycogen (starch) synthase activity
dqs_2453	COG0438	transferase activity, transferring glycosyl groups
dqs_2454	COG0726	polysaccharide deacetylase
dqs_2457	COG0583	DNA-binding transcription factor activity
dqs_2458	COG3829	transcription factor binding
dqs_2464	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
dqs_2466	COG1538	Outer membrane efflux protein
dqs_2468	COG0793	Belongs to the peptidase S41A family
dqs_2477	COG4771	TonB-dependent receptor
dqs_2483	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
dqs_2484	COG0798	PFAM Bile acid sodium symporter
dqs_2487	COG0154	amidase activity
dqs_2489	COG1942	4-Oxalocrotonate Tautomerase
dqs_2490	COG0583	DNA-binding transcription factor activity
dqs_2493	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
dqs_2495	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
dqs_2496	COG0459	protein refolding
dqs_2501	COG2391	methyltransferase activity
dqs_2502	COG2897	thiosulfate sulfurtransferase activity
dqs_2505	COG3001	Fructosamine kinase
dqs_2506	COG0463	Glycosyl transferase, family 2
dqs_2516	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
dqs_2517	COG0235	Class ii aldolase
dqs_2519	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
dqs_2521	COG1024	Enoyl-CoA hydratase
dqs_2528	COG1116	anion transmembrane transporter activity
dqs_2529	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
dqs_2530	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
dqs_2531	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
dqs_2532	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
dqs_2535	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
dqs_2536	COG1116	anion transmembrane transporter activity
dqs_2537	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
dqs_2543	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
dqs_2546	COG5002	protein histidine kinase activity
dqs_2546	COG0784	Response regulator, receiver
dqs_2546	COG2205	protein histidine kinase activity
dqs_2547	COG5001	Diguanylate cyclase
dqs_2547	COG4251	negative regulation of phosphorylation
dqs_2547	COG3706	GGDEF domain
dqs_2547	COG2203	Gaf domain
dqs_2549	COG1764	response to oxidative stress
dqs_2551	COG1522	sequence-specific DNA binding
dqs_2553	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
dqs_2554	COG5002	protein histidine kinase activity
dqs_2554	COG2176	DNA-directed DNA polymerase activity
dqs_2555	COG0745	RESPONSE REGULATOR receiver
dqs_2556	COG5002	protein histidine kinase activity
dqs_2558	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
dqs_2562	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
dqs_2566	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
dqs_2568	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
dqs_2569	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
dqs_2569	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
dqs_2570	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
dqs_2575	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
dqs_2576	COG4569	acetaldehyde dehydrogenase (acetylating) activity
dqs_2577	COG1028	Short-chain dehydrogenase reductase Sdr
dqs_2581	COG1802	Transcriptional regulator
dqs_2591	COG2205	protein histidine kinase activity
dqs_2591	COG3292	Two component regulator propeller
dqs_2591	COG0745	RESPONSE REGULATOR receiver
dqs_2594	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
dqs_2594	COG2205	protein histidine kinase activity
dqs_2600	COG2205	protein histidine kinase activity
dqs_2600	COG2202	Pas domain
dqs_2601	COG2205	protein histidine kinase activity
dqs_2612	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
dqs_2618	COG0028	Belongs to the TPP enzyme family
dqs_2619	COG0583	DNA-binding transcription factor activity
dqs_2620	COG0348	domain, Protein
dqs_2624	COG0446	pyridine nucleotide-disulphide oxidoreductase
dqs_2625	COG1116	anion transmembrane transporter activity
dqs_2625	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
dqs_2626	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
dqs_2627	COG1116	anion transmembrane transporter activity
dqs_2627	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
dqs_2628	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
dqs_2635	COG2205	protein histidine kinase activity
dqs_2635	COG0784	Response regulator, receiver
dqs_2635	COG5002	protein histidine kinase activity
dqs_2637	COG3437	response regulator, receiver
dqs_2642	COG0490	domain, Protein
dqs_2642	COG0471	metal ion transport
dqs_2643	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
dqs_2647	COG1960	acyl-CoA dehydrogenase activity
dqs_2650	COG0183	Belongs to the thiolase family
dqs_2651	COG1024	Enoyl-CoA hydratase
dqs_2652	COG0318	PFAM AMP-dependent synthetase and ligase
dqs_2657	COG1309	transcriptional regulator
dqs_2658	COG1309	transcriptional regulator
dqs_2667	COG3486	L-lysine 6-monooxygenase (NADPH) activity
dqs_2681	COG0583	DNA-binding transcription factor activity
dqs_2684	COG2124	cytochrome p450
dqs_2685	COG0633	Ferredoxin
dqs_2688	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
dqs_2692	COG0667	Aldo Keto reductase
dqs_2699	COG2159	amidohydrolase
dqs_2700	COG2814	Major facilitator Superfamily
dqs_2702	COG2814	Major facilitator Superfamily
dqs_2705	COG0840	transmembrane signaling receptor activity
dqs_2707	COG0617	tRNA 3'-terminal CCA addition
dqs_2721	COG1858	cytochrome C peroxidase
dqs_2727	COG5001	Diguanylate cyclase
dqs_2727	COG5002	protein histidine kinase activity
dqs_2728	COG0583	DNA-binding transcription factor activity
dqs_2729	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
dqs_2737	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
dqs_2738	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
dqs_2739	COG0735	belongs to the Fur family
dqs_2740	COG0497	DNA recombination
dqs_2741	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
dqs_2742	COG1420	regulation of RNA biosynthetic process
dqs_2743	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
dqs_2744	COG1950	PFAM Membrane protein of
dqs_2746	COG2815	serine threonine protein kinase
dqs_2746	COG0515	serine threonine protein kinase
dqs_2747	COG0402	S-adenosylhomocysteine deaminase activity
dqs_2749	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
dqs_2755	COG1858	cytochrome C peroxidase
dqs_2756	COG1858	cytochrome C peroxidase
dqs_2761	COG0583	DNA-binding transcription factor activity
dqs_2763	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
dqs_2764	COG1278	Cold shock
dqs_2768	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
dqs_2769	COG0235	Class ii aldolase
dqs_2773	COG5002	protein histidine kinase activity
dqs_2773	COG5001	Diguanylate cyclase
dqs_2773	COG3447	MASE1 domain protein
dqs_2778	COG0546	phosphoglycolate phosphatase activity
dqs_2779	COG0789	Transcriptional regulator
dqs_2786	COG1429	ligase activity, forming nitrogen-metal bonds
dqs_2789	COG4106	trans-aconitate 2-methyltransferase activity
dqs_2792	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
dqs_2793	COG0412	Dienelactone hydrolase
dqs_2799	COG0306	phosphate transporter
dqs_2802	COG1742	UPF0060 membrane protein
dqs_2806	COG1881	PFAM PEBP family protein
dqs_2809	COG0450	alkyl hydroperoxide reductase
dqs_2814	COG1902	pentaerythritol trinitrate reductase activity
dqs_2815	COG3258	Cytochrome c
dqs_2817	COG4566	intracellular signal transduction
dqs_2818	COG4191	Histidine kinase
dqs_2823	COG3045	CreA protein
dqs_2833	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
dqs_2835	COG1454	alcohol dehydrogenase
dqs_2836	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
dqs_2841	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
dqs_2845	COG2257	FlhB HrpN YscU SpaS Family
dqs_2846	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
dqs_2848	COG1677	Flagellar hook-basal body complex protein FliE
dqs_2854	COG1157	protein secretion by the type III secretion system
dqs_2858	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
dqs_2859	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
dqs_2861	COG1338	Plays a role in the flagellum-specific transport system
dqs_2867	COG3951	Flagellar rod assembly protein muramidase FlgJ
dqs_2867	COG1705	Flagellar rod assembly protein muramidase FlgJ
dqs_2868	COG1706	bacterial-type flagellum-dependent cell motility
dqs_2869	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
dqs_2871	COG4787	bacterial-type flagellum-dependent cell motility
dqs_2874	COG1558	bacterial-type flagellum-dependent cell motility
dqs_2875	COG1815	bacterial-type flagellum-dependent cell motility
dqs_2885	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
dqs_2886	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
dqs_2890	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
dqs_2891	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
dqs_2892	COG0739	heme binding
dqs_2893	COG0316	Belongs to the HesB IscA family
dqs_2894	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
dqs_2895	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
dqs_2897	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
dqs_2899	COG0494	nUDIX hydrolase
dqs_2900	COG0442	prolyl-tRNA aminoacylation
dqs_2901	COG0741	lytic transglycosylase activity
dqs_2903	COG2205	protein histidine kinase activity
dqs_2905	COG2204	response regulator
dqs_2907	COG0482	sulfurtransferase activity
dqs_2915	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
dqs_2916	COG2096	Adenosyltransferase
dqs_2920	COG1132	(ABC) transporter
dqs_2921	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
dqs_2923	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
dqs_2925	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
dqs_2926	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
dqs_2927	COG0521	Mo-molybdopterin cofactor biosynthetic process
dqs_2928	COG3028	Belongs to the UPF0307 family
dqs_2929	COG0312	modulator of DNA gyrase
dqs_2930	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
dqs_2931	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
dqs_2934	COG2205	protein histidine kinase activity
dqs_2935	COG0745	RESPONSE REGULATOR receiver
dqs_2940	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
dqs_2941	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
dqs_2942	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
dqs_2942	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
dqs_2943	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
dqs_2945	COG0793	Belongs to the peptidase S41A family
dqs_2947	COG0588	phosphoglycerate mutase activity
dqs_2949	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
dqs_2951	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
dqs_2953	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
dqs_2954	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
dqs_2955	COG1040	competence protein
dqs_2956	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
dqs_2957	COG2226	methyltransferase
dqs_2961	COG0218	Necessary for normal cell division and for the maintenance of normal septation
dqs_2963	COG2833	Protein of unknown function (DUF455)
dqs_2964	COG0303	'Molybdopterin
dqs_2965	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
dqs_2966	COG0704	Plays a role in the regulation of phosphate uptake
dqs_2967	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
dqs_2969	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
dqs_2969	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
dqs_2971	COG1385	rRNA (uridine-N3-)-methyltransferase activity
dqs_2972	COG0483	inositol monophosphate 1-phosphatase activity
dqs_2975	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
dqs_2976	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
dqs_2978	COG0126	phosphoglycerate kinase activity
dqs_2981	COG0469	pyruvate kinase activity
dqs_2985	COG3284	Transcriptional regulator
dqs_2989	COG0477	Major facilitator Superfamily
dqs_2993	COG3220	belongs to the UPF0276 family
dqs_2995	COG2259	Doxx family
dqs_2996	COG1595	DNA-templated transcription, initiation
dqs_2999	COG2304	oxidoreductase activity
dqs_3001	COG0714	Associated with various cellular activities
dqs_3002	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
dqs_3003	COG2304	oxidoreductase activity
dqs_3006	COG0583	DNA-binding transcription factor activity
dqs_3007	COG3384	dioxygenase
dqs_3008	COG3038	cytochrome b561
dqs_3010	COG2353	YceI-like domain
dqs_3012	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
dqs_3017	COG0339	signal peptide processing
dqs_3018	COG1393	Belongs to the ArsC family
dqs_3019	COG0004	ammonium transporteR
dqs_3022	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
dqs_3024	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
dqs_3025	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
dqs_3026	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
dqs_3027	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
dqs_3030	COG0006	proline dipeptidase activity
dqs_3031	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
dqs_3033	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
dqs_3034	COG0138	bifunctional purine biosynthesis protein purh
dqs_3035	COG0151	Belongs to the GarS family
dqs_3036	COG0408	coproporphyrinogen oxidase activity
dqs_3038	COG0228	four-way junction DNA binding
dqs_3039	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
dqs_3040	COG0336	Belongs to the RNA methyltransferase TrmD family
dqs_3041	COG0335	large ribosomal subunit rRNA binding
dqs_3043	COG0795	lipopolysaccharide-transporting ATPase activity
dqs_3044	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
dqs_3047	COG0525	valine-tRNA ligase activity
dqs_3049	COG0842	Transport permease protein
dqs_3050	COG0842	Transport permease protein
dqs_3050	COG1129	ABC transporter
dqs_3051	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
dqs_3059	COG0425	Belongs to the sulfur carrier protein TusA family
dqs_3061	COG0315	cyclic pyranopterin monophosphate synthase activity
dqs_3063	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
dqs_3069	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
dqs_3070	COG2414	aldehyde ferredoxin oxidoreductase
dqs_3072	COG3284	Transcriptional regulator
dqs_3076	COG3038	cytochrome b561
dqs_3077	COG4654	Cytochrome c, class I
dqs_3079	COG1012	belongs to the aldehyde dehydrogenase family
dqs_3080	COG3284	Transcriptional regulator
dqs_3085	COG5002	protein histidine kinase activity
dqs_3089	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
dqs_3090	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
dqs_3097	COG1595	DNA-templated transcription, initiation
dqs_3100	COG1741	Belongs to the pirin family
dqs_3101	COG2259	Doxx family
dqs_3102	COG0583	DNA-binding transcription factor activity
dqs_3103	COG0655	NAD(P)H dehydrogenase (quinone) activity
dqs_3114	COG3851	Histidine kinase
dqs_3115	COG2197	response regulator
dqs_3116	COG0840	transmembrane signaling receptor activity
dqs_3122	COG4106	trans-aconitate 2-methyltransferase activity
dqs_3125	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
dqs_3126	COG1335	isochorismatase
dqs_3128	COG0583	DNA-binding transcription factor activity
dqs_3130	COG4773	Receptor
dqs_3133	COG4774	siderophore transport
dqs_3135	COG3108	Peptidase M15
dqs_3136	COG2989	Protein conserved in bacteria
dqs_3139	COG0583	DNA-binding transcription factor activity
dqs_3147	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
dqs_3149	COG0069	glutamate synthase activity
dqs_3151	COG0004	ammonium transporteR
dqs_3156	COG1012	belongs to the aldehyde dehydrogenase family
dqs_3158	COG4772	TonB-dependent receptor
dqs_3160	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
dqs_3172	COG3383	formate dehydrogenase (NAD+) activity
dqs_3174	COG1250	3-hydroxyacyl-CoA dehydrogenase
dqs_3175	COG1773	rubredoxin
dqs_3176	COG3321	synthase
dqs_3176	COG0604	alcohol dehydrogenase
dqs_3176	COG1028	Short-chain dehydrogenase reductase Sdr
dqs_3177	COG1024	Enoyl-CoA hydratase
dqs_3189	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
dqs_3193	COG0183	Belongs to the thiolase family
dqs_3200	COG0318	PFAM AMP-dependent synthetase and ligase
dqs_3201	COG2852	Protein conserved in bacteria
dqs_3203	COG1250	3-hydroxyacyl-CoA dehydrogenase
dqs_3203	COG1024	Enoyl-CoA hydratase
dqs_3204	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
dqs_3216	COG1960	acyl-CoA dehydrogenase activity
dqs_3223	COG2010	Cytochrome c
dqs_3230	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
dqs_3232	COG1959	2 iron, 2 sulfur cluster binding
dqs_3233	COG2239	Acts as a magnesium transporter
dqs_3234	COG3245	cytochrome
dqs_3244	COG4263	nitrous-oxide reductase activity
dqs_3247	COG0527	aspartate kinase activity
dqs_3250	COG0720	synthase
dqs_3252	COG3264	Mechanosensitive ion channel
dqs_3252	COG1511	domain protein
dqs_3253	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
dqs_3254	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
dqs_3254	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
dqs_3256	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
dqs_3258	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
dqs_3260	COG0864	Transcriptional regulator
dqs_3262	COG1793	dna ligase
dqs_3263	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
dqs_3266	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
dqs_3268	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
dqs_3269	COG0628	permease
dqs_3270	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
dqs_3272	COG0617	tRNA 3'-terminal CCA addition
dqs_3275	COG1428	Deoxynucleoside kinase
dqs_3276	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
dqs_3277	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
dqs_3278	COG0516	GMP reductase activity
dqs_3278	COG0517	IMP dehydrogenase activity
dqs_3279	COG0308	aminopeptidase N
dqs_3286	COG0028	Belongs to the TPP enzyme family
dqs_3287	COG0440	acetolactate synthase activity
dqs_3288	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
dqs_3289	COG1183	phosphatidylcholine synthase activity
dqs_3291	COG0784	Response regulator, receiver
dqs_3291	COG2205	protein histidine kinase activity
dqs_3291	COG2198	Histidine kinase
dqs_3293	COG3642	lipopolysaccharide core region biosynthetic process
dqs_3294	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
dqs_3297	COG1295	ribonuclease BN
dqs_3299	COG0261	This protein binds to 23S rRNA in the presence of protein L20
dqs_3300	COG0211	Belongs to the bacterial ribosomal protein bL27 family
dqs_3301	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
dqs_3302	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
dqs_3305	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
dqs_3305	COG3320	Male sterility
dqs_3306	COG0220	tRNA (guanine-N7-)-methyltransferase activity
dqs_3308	COG4591	ABC-type transport system involved in lipoprotein release permease component
dqs_3309	COG1136	(ABC) transporter
dqs_3309	COG0577	efflux transmembrane transporter activity
dqs_3310	COG3916	Acyl-homoserine-lactone synthase
dqs_3311	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
dqs_3313	COG0604	alcohol dehydrogenase
dqs_3315	COG1704	LemA family
dqs_3317	COG0488	(ABC) transporter
dqs_3321	COG0741	lytic transglycosylase activity
dqs_3321	COG1196	nuclear chromosome segregation
dqs_3321	COG0739	heme binding
dqs_3324	COG2204	response regulator
dqs_3326	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
dqs_3327	COG2030	dehydratase
dqs_3334	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
dqs_3337	COG0717	Belongs to the dCTP deaminase family
dqs_3338	COG0489	protein tyrosine kinase activity
dqs_3339	COG3047	cAMP biosynthetic process
dqs_3339	COG2885	chlorophyll binding
dqs_3340	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
dqs_3340	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
dqs_3341	COG0659	secondary active sulfate transmembrane transporter activity
dqs_3342	COG1254	Belongs to the acylphosphatase family
dqs_3343	COG1368	sulfuric ester hydrolase activity
dqs_3348	COG0281	malic enzyme
dqs_3348	COG0280	phosphate acetyltransferase
dqs_3349	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
dqs_3350	COG0210	DNA helicase
dqs_3352	COG0495	leucyl-tRNA aminoacylation
dqs_3354	COG1466	dna polymerase III delta subunit
dqs_3355	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
dqs_3356	COG4974	Belongs to the 'phage' integrase family
dqs_3357	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
dqs_3360	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
dqs_3361	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
dqs_3362	COG0828	Belongs to the bacterial ribosomal protein bS21 family
dqs_3369	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
dqs_3376	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
dqs_3377	COG2204	response regulator
dqs_3380	COG0071	Belongs to the small heat shock protein (HSP20) family
dqs_3381	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
dqs_3383	COG0318	PFAM AMP-dependent synthetase and ligase
dqs_3392	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
dqs_3392	COG2755	lipolytic protein G-D-S-L family
dqs_3394	COG5039	Polysaccharide pyruvyl transferase
dqs_3395	COG1215	transferase activity, transferring glycosyl groups
dqs_3397	COG1216	Glycosyl transferase, family 2
dqs_3398	COG1215	transferase activity, transferring glycosyl groups
dqs_3399	COG0438	transferase activity, transferring glycosyl groups
dqs_3400	COG0438	transferase activity, transferring glycosyl groups
dqs_3407	COG0297	glycogen (starch) synthase activity
dqs_3410	COG0367	asparagine synthase
dqs_3412	COG0367	asparagine synthase
dqs_3413	COG0438	transferase activity, transferring glycosyl groups
dqs_3418	COG3267	Type II secretory pathway component ExeA
dqs_3418	COG3409	Peptidoglycan-binding domain 1 protein
dqs_3420	COG0489	protein tyrosine kinase activity
dqs_3425	COG0577	efflux transmembrane transporter activity
dqs_3425	COG1136	(ABC) transporter
dqs_3427	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
dqs_3430	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
dqs_3431	COG1999	signal sequence binding
dqs_3432	COG0109	protoheme IX farnesyltransferase activity
dqs_3433	COG1612	heme a metabolic process
dqs_3439	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
dqs_3441	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
dqs_3443	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
dqs_3444	COG1283	sodium-dependent phosphate transmembrane transporter activity
dqs_3447	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
dqs_3449	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
dqs_3455	COG0604	alcohol dehydrogenase
dqs_3458	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
dqs_3460	COG0134	indole-3-glycerol-phosphate synthase activity
dqs_3461	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
dqs_3464	COG0546	phosphoglycolate phosphatase activity
dqs_3465	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
dqs_3466	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
dqs_3467	COG1234	tRNA 3'-trailer cleavage
dqs_3469	COG0631	protein serine/threonine phosphatase activity
dqs_3470	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
dqs_3471	COG0045	succinate-CoA ligase (ADP-forming) activity
dqs_3474	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
dqs_3476	COG0805	protein transport
dqs_3477	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
dqs_3478	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
dqs_3479	COG0140	phosphoribosyl-ATP diphosphatase activity
dqs_3480	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
dqs_3481	COG0107	imidazoleglycerol-phosphate synthase activity
dqs_3482	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
dqs_3483	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
dqs_3484	COG0131	Imidazoleglycerol-phosphate dehydratase
dqs_3485	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
dqs_3486	COG0741	lytic transglycosylase activity
dqs_3488	COG3119	arylsulfatase activity
dqs_3490	COG1131	(ABC) transporter
dqs_3498	COG0436	Aminotransferase
dqs_3499	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
dqs_3501	COG2084	Dehydrogenase
dqs_3502	COG2084	Dehydrogenase
dqs_3503	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
dqs_3507	COG3411	Ferredoxin
dqs_3509	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
dqs_3511	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
dqs_3517	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
dqs_3519	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
dqs_3522	COG4251	negative regulation of phosphorylation
dqs_3524	COG0629	single-stranded DNA binding
dqs_3525	COG2814	Major facilitator Superfamily
dqs_3528	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
dqs_3529	COG0203	ribosomal protein L17
dqs_3530	COG0202	RNA polymerase activity
dqs_3531	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
dqs_3532	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
dqs_3533	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
dqs_3534	COG0257	Belongs to the bacterial ribosomal protein bL36 family
dqs_3535	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
dqs_3536	COG0201	protein transport
dqs_3537	COG0200	Binds to the 23S rRNA
dqs_3538	COG1841	ribosomal large subunit assembly
dqs_3539	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
dqs_3540	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
dqs_3541	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
dqs_3542	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
dqs_3543	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
dqs_3544	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
dqs_3545	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
dqs_3546	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
dqs_3547	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
dqs_3548	COG0255	Belongs to the universal ribosomal protein uL29 family
dqs_3549	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
dqs_3550	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
dqs_3551	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
dqs_3552	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
dqs_3553	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
dqs_3554	COG0089	rRNA binding
dqs_3555	COG0088	Forms part of the polypeptide exit tunnel
dqs_3556	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
dqs_3557	COG0051	transcription antitermination factor activity, RNA binding
dqs_3558	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
dqs_3559	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
dqs_3560	COG0049	tRNA binding
dqs_3561	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
dqs_3562	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
dqs_3563	COG0085	RNA polymerase activity
dqs_3564	COG0222	ribosome binding
dqs_3565	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
dqs_3566	COG0081	regulation of translation
dqs_3567	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
dqs_3569	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
dqs_3571	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
dqs_3575	COG0277	FAD linked oxidase domain protein
dqs_3579	COG2197	response regulator
dqs_3581	COG0784	Response regulator, receiver
dqs_3581	COG2198	Histidine kinase
dqs_3581	COG2205	protein histidine kinase activity
dqs_3583	COG1804	L-carnitine dehydratase bile acid-inducible protein F
dqs_3588	COG0559	Belongs to the binding-protein-dependent transport system permease family
dqs_3590	COG1022	Amp-dependent synthetase and ligase
dqs_3592	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
dqs_3593	COG0352	thiamine-phosphate diphosphorylase activity
dqs_3599	COG0840	transmembrane signaling receptor activity
dqs_3601	COG0415	Belongs to the DNA photolyase family
dqs_3602	COG1678	Uncharacterized ACR, COG1678
dqs_3603	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
dqs_3604	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
dqs_3605	COG0540	Belongs to the ATCase OTCase family
dqs_3607	COG1872	DUF167
dqs_3608	COG0762	integral membrane protein
dqs_3618	COG3290	protein histidine kinase activity
dqs_3618	COG0840	transmembrane signaling receptor activity
dqs_3619	COG0840	transmembrane signaling receptor activity
dqs_3624	COG0437	4 iron, 4 sulfur cluster binding
dqs_3625	COG3383	formate dehydrogenase (NAD+) activity
dqs_3625	COG0243	molybdopterin cofactor binding
dqs_3632	COG0746	molybdenum cofactor guanylyltransferase activity
dqs_3634	COG1763	Mo-molybdopterin cofactor biosynthetic process
dqs_3635	COG3852	Histidine kinase
dqs_3637	COG1981	membrane
dqs_3640	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
dqs_3641	COG5002	protein histidine kinase activity
dqs_3643	COG4654	Cytochrome c, class I
dqs_3644	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
dqs_3645	COG0830	nickel cation binding
dqs_3646	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
dqs_3647	COG0804	urea catabolic process
dqs_3648	COG0832	Belongs to the urease beta subunit family
dqs_3650	COG0831	urea catabolic process
dqs_3651	COG0829	nickel cation binding
dqs_3652	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
dqs_3652	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
dqs_3653	COG1368	sulfuric ester hydrolase activity
dqs_3655	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
dqs_3656	COG1116	anion transmembrane transporter activity
dqs_3657	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
dqs_3658	COG1733	regulation of RNA biosynthetic process
dqs_3660	COG1492	cobalamin metabolic process
dqs_3665	COG0513	Belongs to the DEAD box helicase family
dqs_3666	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
dqs_3667	COG0778	Nitroreductase
dqs_3670	COG5001	Diguanylate cyclase
dqs_3670	COG5002	protein histidine kinase activity
dqs_3675	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
dqs_3681	COG3411	Ferredoxin
dqs_3683	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
dqs_3684	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
dqs_3685	COG0625	glutathione transferase activity
dqs_3687	COG0427	acetyl-CoA hydrolase
dqs_3689	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
dqs_3692	COG0688	phosphatidylethanolamine metabolic process
dqs_3693	COG1797	cobyrinic acid a,c-diamide synthase activity
dqs_3694	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
dqs_3694	COG1648	precorrin-2 dehydrogenase activity
dqs_3696	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
dqs_3697	COG4139	cobalamin transport
dqs_3698	COG4206	TonB-dependent receptor
dqs_3701	COG0501	Belongs to the peptidase M48B family
dqs_3702	COG4269	membrane
dqs_3703	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
dqs_3704	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
dqs_3706	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
dqs_3706	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
dqs_3707	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
dqs_3708	COG0859	PFAM glycosyl transferase family 9
dqs_3710	COG0438	transferase activity, transferring glycosyl groups
dqs_3715	COG1132	(ABC) transporter
dqs_3721	COG0438	transferase activity, transferring glycosyl groups
dqs_3722	COG2192	nodulation
dqs_3723	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
dqs_3723	COG2755	lipolytic protein G-D-S-L family
dqs_3725	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
dqs_3729	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
dqs_3738	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
dqs_3742	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
dqs_3747	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
dqs_3750	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
dqs_3751	COG0799	negative regulation of ribosome biogenesis
dqs_3752	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
dqs_3753	COG0242	peptide deformylase activity
dqs_3754	COG0424	maF-like protein
dqs_3755	COG1530	ribonuclease E activity
dqs_3761	COG0583	DNA-binding transcription factor activity
dqs_3764	COG2818	Glycosylase
dqs_3766	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
dqs_3767	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
dqs_3769	COG0443	Heat shock 70 kDa protein
dqs_3770	COG0741	lytic transglycosylase activity
dqs_3774	COG0583	DNA-binding transcription factor activity
dqs_3775	COG2814	Major facilitator Superfamily
dqs_3777	COG1132	(ABC) transporter
dqs_3782	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
dqs_3787	COG0069	glutamate synthase activity
dqs_3787	COG0070	glutamate synthase
dqs_3787	COG0067	glutamate synthase
dqs_3788	COG0232	Belongs to the dGTPase family. Type 2 subfamily
dqs_3789	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
dqs_3790	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
dqs_3797	COG1965	Belongs to the frataxin family
dqs_3803	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
dqs_3804	COG0284	orotidine-5'-phosphate decarboxylase activity
dqs_3806	COG0243	molybdopterin cofactor binding
dqs_3808	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
dqs_3809	COG0708	Exodeoxyribonuclease III
dqs_3812	COG4575	ribosome binding
dqs_3815	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
dqs_3819	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
dqs_3821	COG0625	glutathione transferase activity
dqs_3822	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
dqs_3834	COG0812	UDP-N-acetylmuramate dehydrogenase activity
dqs_3836	COG0840	transmembrane signaling receptor activity
dqs_3840	COG0180	Tryptophanyl-tRNA synthetase
dqs_3844	COG3876	Protein conserved in bacteria
dqs_3845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
dqs_3847	COG2226	methyltransferase
dqs_3848	COG2020	methyltransferase activity
dqs_3850	COG2169	Transcriptional regulator
dqs_3850	COG1917	Cupin 2, conserved barrel domain protein
dqs_3851	COG4106	trans-aconitate 2-methyltransferase activity
dqs_3854	COG0456	acetyltransferase
dqs_3857	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
dqs_3858	COG2816	NAD+ diphosphatase activity
dqs_3886	COG2814	Major facilitator Superfamily
dqs_3890	COG0347	Belongs to the P(II) protein family
dqs_3891	COG0004	ammonium transporteR
dqs_3892	COG3047	cAMP biosynthetic process
dqs_3893	COG0788	formyltetrahydrofolate deformylase activity
dqs_3896	COG0488	(ABC) transporter
dqs_3901	COG1335	isochorismatase
dqs_3904	COG0506	proline dehydrogenase activity
dqs_3904	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
dqs_3904	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
dqs_3906	COG0189	ligase activity
dqs_3910	COG2703	oxygen carrier activity
dqs_3918	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
dqs_3919	COG0753	catalase activity
dqs_3920	COG0402	S-adenosylhomocysteine deaminase activity
dqs_3921	COG1652	LysM domain
dqs_3925	COG2815	serine threonine protein kinase
dqs_3925	COG0515	serine threonine protein kinase
dqs_3926	COG0826	peptidase U32
dqs_3928	COG3706	GGDEF domain
dqs_3930	COG0488	(ABC) transporter
dqs_3931	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
dqs_3931	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
dqs_3932	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
dqs_3933	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
dqs_3938	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
dqs_3939	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
dqs_3947	COG1773	rubredoxin
dqs_3951	COG0375	protein maturation
dqs_3953	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
dqs_3955	COG0409	Hydrogenase expression formation protein
dqs_3956	COG0309	Hydrogenase expression formation protein (HypE)
dqs_3957	COG2204	response regulator
dqs_3963	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
dqs_3964	COG1194	a g-specific adenine glycosylase
dqs_3974	COG1970	mechanosensitive ion channel activity
dqs_3975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
dqs_3978	COG3842	ATPase activity
dqs_3980	COG1349	DNA-binding transcription factor activity
dqs_3982	COG4302	ethanolamine ammonia-lyase activity
dqs_3990	COG3585	molybdate ion transport
dqs_3990	COG2005	Transcriptional regulator
dqs_3992	COG2982	Protein involved in outer membrane biogenesis
dqs_3994	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
dqs_3995	COG1074	ATP-dependent DNA helicase activity
dqs_3996	COG4206	TonB-dependent receptor
dqs_3998	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
dqs_3999	COG1785	Belongs to the alkaline phosphatase family
dqs_4001	COG1024	Enoyl-CoA hydratase
dqs_4001	COG1250	3-hydroxyacyl-CoA dehydrogenase
dqs_4002	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
dqs_4003	COG0583	DNA-binding transcription factor activity
dqs_4004	COG0473	3-isopropylmalate dehydrogenase activity
dqs_4005	COG3530	Putative quorum-sensing-regulated virulence factor
dqs_4006	COG2095	MarC family integral membrane protein
dqs_4011	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
dqs_4012	COG0022	dehydrogenase e1 component
dqs_4015	COG0095	Lipoate-protein ligase
dqs_4019	COG3284	Transcriptional regulator
dqs_4029	COG0631	protein serine/threonine phosphatase activity
dqs_4053	COG0840	transmembrane signaling receptor activity
dqs_4055	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
dqs_4058	COG1028	Short-chain dehydrogenase reductase Sdr
dqs_4059	COG0475	glutathione-regulated potassium exporter activity
dqs_4060	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
dqs_4068	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
dqs_4069	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
dqs_4071	COG4235	cytochrome complex assembly
dqs_4072	COG3088	subunit of a heme lyase
dqs_4073	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
dqs_4075	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
dqs_4078	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
dqs_4079	COG4133	protoheme IX ABC transporter activity
dqs_4081	COG3005	denitrification pathway
dqs_4082	COG3043	anaerobic respiration
dqs_4083	COG0348	domain, Protein
dqs_4084	COG0437	4 iron, 4 sulfur cluster binding
dqs_4085	COG0243	molybdopterin cofactor binding
dqs_4087	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
dqs_4087	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
dqs_4088	COG0784	Response regulator, receiver
dqs_4088	COG2205	protein histidine kinase activity
dqs_4088	COG5002	protein histidine kinase activity
dqs_4089	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
dqs_4089	COG2205	protein histidine kinase activity
dqs_4090	COG2205	protein histidine kinase activity
dqs_4090	COG3437	response regulator, receiver
dqs_4090	COG3850	Histidine kinase
dqs_4090	COG4999	Histidine kinase
dqs_4091	COG2176	DNA-directed DNA polymerase activity
dqs_4091	COG5002	protein histidine kinase activity
dqs_4092	COG2226	methyltransferase
dqs_4094	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
dqs_4095	COG1758	RNA polymerase activity
dqs_4096	COG0194	GDP metabolic process
dqs_4100	COG0587	DNA-directed DNA polymerase activity
dqs_4102	COG0789	Transcriptional regulator
dqs_4103	COG1561	YicC-like family, N-terminal region
dqs_4104	COG0515	serine threonine protein kinase
dqs_4104	COG3266	domain, Protein
dqs_4105	COG0631	protein serine/threonine phosphatase activity
dqs_4106	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
dqs_4107	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
dqs_4108	COG0635	Involved in the biosynthesis of porphyrin-containing compound
dqs_4110	COG0616	signal peptide processing
dqs_4111	COG0220	tRNA (guanine-N7-)-methyltransferase activity
dqs_4112	COG2022	thiamine diphosphate biosynthetic process
dqs_4114	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
dqs_4115	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
dqs_4115	COG2813	Specifically methylates the guanine in position
dqs_4118	COG2223	nitrite transmembrane transporter activity
dqs_4120	COG0288	reversible hydration of carbon dioxide
dqs_4121	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
dqs_4122	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
dqs_4123	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
dqs_4124	COG0569	domain protein
dqs_4125	COG2204	response regulator
dqs_4126	COG5000	phosphorelay sensor kinase activity
dqs_4129	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
dqs_4130	COG0730	response to heat
dqs_4131	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
dqs_4132	COG0706	membrane insertase activity
dqs_4133	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
dqs_4134	COG0594	ribonuclease P activity
dqs_4135	COG0230	Belongs to the bacterial ribosomal protein bL34 family