locus-tag	class	description
AzCIB_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AzCIB_0004	COG4974	Belongs to the 'phage' integrase family
AzCIB_0005	COG0517	IMP dehydrogenase activity
AzCIB_0012	COG0686	Belongs to the AlaDH PNT family
AzCIB_0015	COG3706	GGDEF domain
AzCIB_0016	COG0583	DNA-binding transcription factor activity
AzCIB_0017	COG1960	acyl-CoA dehydrogenase activity
AzCIB_0018	COG4251	negative regulation of phosphorylation
AzCIB_0019	COG0784	Response regulator, receiver
AzCIB_0021	COG2974	May be involved in recombination
AzCIB_0023	COG1187	pseudouridine synthase activity
AzCIB_0025	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AzCIB_0027	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AzCIB_0031	COG0583	DNA-binding transcription factor activity
AzCIB_0034	COG3909	cytochrome
AzCIB_0035	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AzCIB_0036	COG4206	TonB-dependent receptor
AzCIB_0038	COG0446	pyridine nucleotide-disulphide oxidoreductase
AzCIB_0040	COG2922	Belongs to the Smg family
AzCIB_0041	COG0758	DNA mediated transformation
AzCIB_0043	COG0242	peptide deformylase activity
AzCIB_0044	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AzCIB_0045	COG0501	Belongs to the peptidase M48B family
AzCIB_0046	COG4191	Histidine kinase
AzCIB_0047	COG2204	response regulator
AzCIB_0048	COG1763	Mo-molybdopterin cofactor biosynthetic process
AzCIB_0051	COG0746	molybdenum cofactor guanylyltransferase activity
AzCIB_0059	COG3383	formate dehydrogenase (NAD+) activity
AzCIB_0059	COG0243	molybdopterin cofactor binding
AzCIB_0060	COG0437	4 iron, 4 sulfur cluster binding
AzCIB_0065	COG4953	penicillin-binding protein 1C
AzCIB_0066	COG2373	Large extracellular alpha-helical protein
AzCIB_0069	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AzCIB_0070	COG0765	amino acid transport
AzCIB_0071	COG0765	amino acid transport
AzCIB_0072	COG1126	abc transporter atp-binding protein
AzCIB_0073	COG2824	Alkylphosphonate utilization operon protein PhnA
AzCIB_0077	COG0445	tRNA wobble uridine modification
AzCIB_0078	COG0357	Ribosomal RNA small subunit methyltransferase G
AzCIB_0079	COG1192	Involved in chromosome partitioning
AzCIB_0080	COG1475	DNA binding
AzCIB_0082	COG0356	it plays a direct role in the translocation of protons across the membrane
AzCIB_0084	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AzCIB_0085	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AzCIB_0086	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AzCIB_0087	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AzCIB_0088	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AzCIB_0089	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AzCIB_0092	COG2226	methyltransferase
AzCIB_0094	COG0745	RESPONSE REGULATOR receiver
AzCIB_0098	COG0121	glutamine amidotransferase
AzCIB_0099	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AzCIB_0101	COG0154	amidase activity
AzCIB_0102	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AzCIB_0103	COG1077	Cell shape determining protein MreB Mrl
AzCIB_0106	COG0768	penicillin binding
AzCIB_0107	COG0772	Belongs to the SEDS family
AzCIB_0109	COG1686	Belongs to the peptidase S11 family
AzCIB_0111	COG2921	Belongs to the UPF0250 family
AzCIB_0112	COG0321	lipoyl(octanoyl) transferase activity
AzCIB_0113	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AzCIB_0114	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AzCIB_0120	COG4566	intracellular signal transduction
AzCIB_0123	COG3245	cytochrome
AzCIB_0133	COG0514	ATP-dependent DNA helicase (RecQ)
AzCIB_0135	COG0500	methyltransferase
AzCIB_0138	COG2814	Major facilitator Superfamily
AzCIB_0141	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AzCIB_0142	COG3963	phosphatidate phosphatase activity
AzCIB_0144	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AzCIB_0148	COG3501	Rhs element vgr protein
AzCIB_0149	COG1132	(ABC) transporter
AzCIB_0155	COG3204	pilus organization
AzCIB_0156	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AzCIB_0157	COG1074	ATP-dependent DNA helicase activity
AzCIB_0160	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AzCIB_0162	COG5002	protein histidine kinase activity
AzCIB_0163	COG2204	response regulator
AzCIB_0165	COG2165	general secretion pathway protein
AzCIB_0166	COG0739	heme binding
AzCIB_0166	COG0741	lytic transglycosylase activity
AzCIB_0166	COG1196	nuclear chromosome segregation
AzCIB_0176	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AzCIB_0183	COG1450	Type ii and iii secretion system protein
AzCIB_0185	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AzCIB_0187	COG0477	Major facilitator Superfamily
AzCIB_0188	COG4191	Histidine kinase
AzCIB_0189	COG2204	response regulator
AzCIB_0192	COG1278	Cold shock
AzCIB_0198	COG0745	RESPONSE REGULATOR receiver
AzCIB_0201	COG0330	HflC and HflK could
AzCIB_0206	COG0477	Major facilitator Superfamily
AzCIB_0208	COG1305	Transglutaminase-like
AzCIB_0209	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AzCIB_0212	COG3045	CreA protein
AzCIB_0214	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AzCIB_0215	COG0484	heat shock protein binding
AzCIB_0220	COG0194	GDP metabolic process
AzCIB_0221	COG1758	RNA polymerase activity
AzCIB_0222	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AzCIB_0224	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AzCIB_0229	COG3850	Histidine kinase
AzCIB_0230	COG2197	response regulator
AzCIB_0233	COG0243	molybdopterin cofactor binding
AzCIB_0234	COG0437	4 iron, 4 sulfur cluster binding
AzCIB_0235	COG0348	domain, Protein
AzCIB_0236	COG3043	anaerobic respiration
AzCIB_0237	COG3005	denitrification pathway
AzCIB_0238	COG4133	protoheme IX ABC transporter activity
AzCIB_0239	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AzCIB_0242	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AzCIB_0244	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AzCIB_0245	COG3088	subunit of a heme lyase
AzCIB_0246	COG4235	cytochrome complex assembly
AzCIB_0246	COG3088	subunit of a heme lyase
AzCIB_0251	COG2204	response regulator
AzCIB_0252	COG4191	Histidine kinase
AzCIB_0257	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AzCIB_0259	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AzCIB_0264	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AzCIB_0265	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AzCIB_0276	COG3245	cytochrome
AzCIB_0277	COG2010	Cytochrome c
AzCIB_0282	COG1216	Glycosyl transferase, family 2
AzCIB_0290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AzCIB_0297	COG0714	Associated with various cellular activities
AzCIB_0299	COG0463	Glycosyl transferase, family 2
AzCIB_0302	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AzCIB_0311	COG3706	GGDEF domain
AzCIB_0313	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AzCIB_0317	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AzCIB_0318	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AzCIB_0325	COG1879	ABC-type sugar transport system periplasmic component
AzCIB_0330	COG1368	sulfuric ester hydrolase activity
AzCIB_0334	COG1024	Enoyl-CoA hydratase
AzCIB_0335	COG1250	3-hydroxyacyl-CoA dehydrogenase
AzCIB_0336	COG2050	protein possibly involved in aromatic compounds catabolism
AzCIB_0338	COG3396	Phenylacetate-CoA oxygenase
AzCIB_0339	COG3460	Phenylacetate-CoA oxygenase
AzCIB_0340	COG3396	Phenylacetate-CoA oxygenase
AzCIB_0341	COG2151	metal-sulfur cluster biosynthetic enzyme
AzCIB_0342	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AzCIB_0344	COG0683	leucine binding
AzCIB_0346	COG0411	ABC transporter
AzCIB_0349	COG0583	DNA-binding transcription factor activity
AzCIB_0350	COG4191	Histidine kinase
AzCIB_0351	COG4566	intracellular signal transduction
AzCIB_0353	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AzCIB_0360	COG0513	Belongs to the DEAD box helicase family
AzCIB_0361	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AzCIB_0362	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AzCIB_0365	COG4232	protein-disulfide reductase activity
AzCIB_0366	COG1324	tolerance protein
AzCIB_0374	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AzCIB_0383	COG0861	Integral membrane protein TerC family
AzCIB_0384	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AzCIB_0387	COG0348	domain, Protein
AzCIB_0390	COG0625	glutathione transferase activity
AzCIB_0391	COG0596	Alpha beta hydrolase
AzCIB_0391	COG2945	thiolester hydrolase activity
AzCIB_0405	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AzCIB_0409	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AzCIB_0410	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AzCIB_0411	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AzCIB_0414	COG0018	arginyl-trna synthetase
AzCIB_0416	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AzCIB_0417	COG0300	oxidoreductase activity
AzCIB_0418	COG2902	Dehydrogenase
AzCIB_0420	COG0826	peptidase U32
AzCIB_0422	COG3158	transport of potassium into the cell
AzCIB_0423	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AzCIB_0425	COG3243	poly(R)-hydroxyalkanoic acid synthase
AzCIB_0426	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AzCIB_0427	COG0789	Transcriptional regulator
AzCIB_0428	COG0288	reversible hydration of carbon dioxide
AzCIB_0429	COG0183	Belongs to the thiolase family
AzCIB_0430	COG1960	acyl-CoA dehydrogenase activity
AzCIB_0435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AzCIB_0436	COG1660	Displays ATPase and GTPase activities
AzCIB_0440	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AzCIB_0444	COG1301	dicarboxylic acid transport
AzCIB_0446	COG1053	succinate dehydrogenase
AzCIB_0447	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AzCIB_0451	COG2864	formate dehydrogenase
AzCIB_0452	COG0217	transcriptional regulatory protein
AzCIB_0454	COG0433	COG0433 Predicted ATPase
AzCIB_0461	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AzCIB_0463	COG1278	Cold shock
AzCIB_0464	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AzCIB_0466	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AzCIB_0468	COG1560	Kdo2-lipid A biosynthetic process
AzCIB_0469	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AzCIB_0471	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AzCIB_0473	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AzCIB_0475	COG2255	four-way junction helicase activity
AzCIB_0476	COG0632	four-way junction helicase activity
AzCIB_0477	COG1530	ribonuclease E activity
AzCIB_0478	COG0424	maF-like protein
AzCIB_0482	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AzCIB_0483	COG0799	negative regulation of ribosome biogenesis
AzCIB_0484	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AzCIB_0487	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AzCIB_0491	COG1115	amino acid carrier protein
AzCIB_0492	COG2192	nodulation
AzCIB_0493	COG0438	transferase activity, transferring glycosyl groups
AzCIB_0500	COG1132	(ABC) transporter
AzCIB_0501	COG1368	sulfuric ester hydrolase activity
AzCIB_0508	COG0438	transferase activity, transferring glycosyl groups
AzCIB_0509	COG0859	PFAM glycosyl transferase family 9
AzCIB_0511	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AzCIB_0512	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AzCIB_0512	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AzCIB_0514	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AzCIB_0515	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AzCIB_0519	COG4206	TonB-dependent receptor
AzCIB_0520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AzCIB_0521	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AzCIB_0523	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AzCIB_0523	COG1648	precorrin-2 dehydrogenase activity
AzCIB_0525	COG2818	Glycosylase
AzCIB_0526	COG0583	DNA-binding transcription factor activity
AzCIB_0531	COG0247	lactate metabolic process
AzCIB_0532	COG0697	spore germination
AzCIB_0535	COG0583	DNA-binding transcription factor activity
AzCIB_0536	COG1032	radical SAM domain protein
AzCIB_0538	COG0741	lytic transglycosylase activity
AzCIB_0540	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AzCIB_0541	COG0281	malic enzyme
AzCIB_0541	COG0280	phosphate acetyltransferase
AzCIB_0543	COG1686	Belongs to the peptidase S11 family
AzCIB_0545	COG1187	pseudouridine synthase activity
AzCIB_0546	COG0577	efflux transmembrane transporter activity
AzCIB_0546	COG1136	(ABC) transporter
AzCIB_0547	COG1136	(ABC) transporter
AzCIB_0547	COG0577	efflux transmembrane transporter activity
AzCIB_0548	COG1136	(ABC) transporter
AzCIB_0548	COG0577	efflux transmembrane transporter activity
AzCIB_0549	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AzCIB_0550	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AzCIB_0551	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AzCIB_0554	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AzCIB_0554	COG0493	'glutamate synthase
AzCIB_0557	COG1643	Atp-dependent helicase
AzCIB_0558	COG0360	Binds together with S18 to 16S ribosomal RNA
AzCIB_0559	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AzCIB_0560	COG0359	binds to the 23S rRNA
AzCIB_0561	COG0305	Participates in initiation and elongation during chromosome replication
AzCIB_0562	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AzCIB_0563	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AzCIB_0564	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AzCIB_0568	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AzCIB_0569	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AzCIB_0570	COG0237	dephospho-CoA kinase activity
AzCIB_0572	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
AzCIB_0573	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AzCIB_0576	COG3852	Histidine kinase
AzCIB_0581	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AzCIB_0582	COG3568	Endonuclease Exonuclease Phosphatase
AzCIB_0583	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AzCIB_0586	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AzCIB_0591	COG0463	Glycosyl transferase, family 2
AzCIB_0594	COG0564	pseudouridine synthase activity
AzCIB_0595	COG0012	GTP binding
AzCIB_0596	COG0193	aminoacyl-tRNA hydrolase activity
AzCIB_0597	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AzCIB_0598	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AzCIB_0599	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AzCIB_0600	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AzCIB_0602	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AzCIB_0603	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AzCIB_0604	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AzCIB_0605	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AzCIB_0606	COG0742	ribosomal rna small subunit methyltransferase
AzCIB_0608	COG0612	Peptidase, M16
AzCIB_0610	COG2884	Cell division ATP-binding protein ftsE
AzCIB_0611	COG2177	Part of the ABC transporter FtsEX involved in
AzCIB_0616	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AzCIB_0617	COG1607	acyl-coa hydrolase
AzCIB_0618	COG2703	oxygen carrier activity
AzCIB_0619	COG3622	Belongs to the hyi family
AzCIB_0620	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AzCIB_0621	COG0251	oxidation-reduction process
AzCIB_0629	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AzCIB_0630	COG1702	phosphate starvation-inducible protein PhoH
AzCIB_0631	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AzCIB_0632	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AzCIB_0633	COG0752	glycyl-tRNA synthetase alpha subunit
AzCIB_0634	COG0751	glycine-tRNA ligase activity
AzCIB_0635	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AzCIB_0636	COG0204	Acyl-transferase
AzCIB_0640	COG1024	Enoyl-CoA hydratase
AzCIB_0641	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AzCIB_0645	COG1127	ABC transporter
AzCIB_0646	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AzCIB_0647	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AzCIB_0651	COG1131	(ABC) transporter
AzCIB_0652	COG0842	Transport permease protein
AzCIB_0654	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AzCIB_0655	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AzCIB_0656	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AzCIB_0657	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AzCIB_0658	COG0131	Imidazoleglycerol-phosphate dehydratase
AzCIB_0659	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AzCIB_0660	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AzCIB_0661	COG0107	imidazoleglycerol-phosphate synthase activity
AzCIB_0662	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AzCIB_0663	COG0140	phosphoribosyl-ATP diphosphatase activity
AzCIB_0665	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AzCIB_0666	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AzCIB_0667	COG0805	protein transport
AzCIB_0668	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AzCIB_0669	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AzCIB_0672	COG0045	succinate-CoA ligase (ADP-forming) activity
AzCIB_0673	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AzCIB_0680	COG2878	Part of a membrane complex involved in electron transport
AzCIB_0681	COG4657	Part of a membrane complex involved in electron transport
AzCIB_0682	COG3485	protocatechuate 3,4-dioxygenase
AzCIB_0688	COG5420	small protein containing a coiled-coil domain
AzCIB_0691	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AzCIB_0693	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AzCIB_0696	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AzCIB_0698	COG0306	phosphate transporter
AzCIB_0704	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AzCIB_0706	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
AzCIB_0711	COG5554	nitrogen fixation
AzCIB_0716	COG0105	UTP biosynthetic process
AzCIB_0717	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AzCIB_0720	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AzCIB_0721	COG0124	histidyl-tRNA synthetase
AzCIB_0722	COG2976	Protein conserved in bacteria
AzCIB_0723	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AzCIB_0724	COG1160	GTP binding
AzCIB_0725	COG1923	regulation of RNA biosynthetic process
AzCIB_0726	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AzCIB_0727	COG0330	HflC and HflK could
AzCIB_0728	COG0330	HflC and HflK could
AzCIB_0730	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AzCIB_0731	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AzCIB_0732	COG0557	exoribonuclease II activity
AzCIB_0733	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AzCIB_0734	COG3707	response regulator
AzCIB_0735	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AzCIB_0736	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AzCIB_0737	COG1116	anion transmembrane transporter activity
AzCIB_0740	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AzCIB_0742	COG2223	nitrite transmembrane transporter activity
AzCIB_0743	COG0515	serine threonine protein kinase
AzCIB_0744	COG0243	molybdopterin cofactor binding
AzCIB_0748	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AzCIB_0749	COG2252	PERMEase
AzCIB_0750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AzCIB_0752	COG1752	Esterase of the alpha-beta hydrolase superfamily
AzCIB_0754	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AzCIB_0755	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AzCIB_0756	COG0723	plastoquinol--plastocyanin reductase activity
AzCIB_0757	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AzCIB_0758	COG2857	Cytochrome c1
AzCIB_0759	COG0625	glutathione transferase activity
AzCIB_0760	COG2969	positive regulation of protein catabolic process
AzCIB_0761	COG0438	transferase activity, transferring glycosyl groups
AzCIB_0762	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AzCIB_0763	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AzCIB_0771	COG1448	Aminotransferase
AzCIB_0772	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AzCIB_0773	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AzCIB_0774	COG0459	protein refolding
AzCIB_0775	COG0745	RESPONSE REGULATOR receiver
AzCIB_0776	COG0642	Histidine kinase
AzCIB_0777	COG3162	membrane
AzCIB_0779	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AzCIB_0780	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AzCIB_0787	COG2815	serine threonine protein kinase
AzCIB_0787	COG0515	serine threonine protein kinase
AzCIB_0788	COG0165	Argininosuccinate lyase
AzCIB_0790	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AzCIB_0791	COG0181	hydroxymethylbilane synthase activity
AzCIB_0793	COG2959	enzyme of heme biosynthesis
AzCIB_0795	COG0408	coproporphyrinogen oxidase activity
AzCIB_0796	COG0151	Belongs to the GarS family
AzCIB_0798	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AzCIB_0800	COG0745	RESPONSE REGULATOR receiver
AzCIB_0800	COG3706	GGDEF domain
AzCIB_0801	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AzCIB_0802	COG0006	proline dipeptidase activity
AzCIB_0805	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AzCIB_0806	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AzCIB_0807	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AzCIB_0808	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AzCIB_0810	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AzCIB_0813	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AzCIB_0819	COG0489	protein tyrosine kinase activity
AzCIB_0829	COG0438	transferase activity, transferring glycosyl groups
AzCIB_0830	COG2244	polysaccharide biosynthetic process
AzCIB_0831	COG2327	Polysaccharide pyruvyl transferase
AzCIB_0833	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AzCIB_0835	COG0339	signal peptide processing
AzCIB_0837	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AzCIB_0839	COG2885	chlorophyll binding
AzCIB_0840	COG5001	Diguanylate cyclase
AzCIB_0840	COG5002	protein histidine kinase activity
AzCIB_0843	COG3706	GGDEF domain
AzCIB_0843	COG0745	RESPONSE REGULATOR receiver
AzCIB_0846	COG0778	Nitroreductase
AzCIB_0847	COG0469	pyruvate kinase activity
AzCIB_0850	COG0126	phosphoglycerate kinase activity
AzCIB_0851	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AzCIB_0852	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AzCIB_0853	COG3954	Phosphoribulokinase
AzCIB_0855	COG0483	inositol monophosphate 1-phosphatase activity
AzCIB_0856	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AzCIB_0858	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AzCIB_0858	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AzCIB_0859	COG5001	Diguanylate cyclase
AzCIB_0859	COG5002	protein histidine kinase activity
AzCIB_0859	COG3447	MASE1 domain protein
AzCIB_0860	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AzCIB_0862	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AzCIB_0863	COG0303	'Molybdopterin
AzCIB_0865	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AzCIB_0868	COG2226	methyltransferase
AzCIB_0869	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AzCIB_0870	COG1040	competence protein
AzCIB_0871	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AzCIB_0872	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AzCIB_0874	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AzCIB_0876	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AzCIB_0877	COG0640	Transcriptional regulator
AzCIB_0878	COG0588	phosphoglycerate mutase activity
AzCIB_0880	COG0793	Belongs to the peptidase S41A family
AzCIB_0882	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AzCIB_0883	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AzCIB_0883	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AzCIB_0884	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AzCIB_0885	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AzCIB_0886	COG0406	alpha-ribazole phosphatase activity
AzCIB_0887	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AzCIB_0889	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AzCIB_0890	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AzCIB_0891	COG0312	modulator of DNA gyrase
AzCIB_0892	COG3028	Belongs to the UPF0307 family
AzCIB_0893	COG0521	Mo-molybdopterin cofactor biosynthetic process
AzCIB_0894	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AzCIB_0895	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AzCIB_0898	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AzCIB_0899	COG2096	Adenosyltransferase
AzCIB_0900	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AzCIB_0908	COG0482	sulfurtransferase activity
AzCIB_0913	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AzCIB_0915	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AzCIB_0916	COG0312	modulator of DNA gyrase
AzCIB_0918	COG2204	response regulator
AzCIB_0920	COG2205	protein histidine kinase activity
AzCIB_0923	COG0741	lytic transglycosylase activity
AzCIB_0924	COG0442	prolyl-tRNA aminoacylation
AzCIB_0925	COG0494	nUDIX hydrolase
AzCIB_0929	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
AzCIB_0930	COG1765	OsmC-like protein
AzCIB_0931	COG3033	Beta-eliminating lyase
AzCIB_0932	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AzCIB_0933	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AzCIB_0934	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AzCIB_0935	COG0316	Belongs to the HesB IscA family
AzCIB_0936	COG0739	heme binding
AzCIB_0936	COG0741	lytic transglycosylase activity
AzCIB_0936	COG1196	nuclear chromosome segregation
AzCIB_0937	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AzCIB_0945	COG1815	bacterial-type flagellum-dependent cell motility
AzCIB_0946	COG1558	bacterial-type flagellum-dependent cell motility
AzCIB_0947	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AzCIB_0948	COG1749	Flagellar hook protein flgE
AzCIB_0949	COG4787	bacterial-type flagellum-dependent cell motility
AzCIB_0950	COG4786	Flagellar basal body rod
AzCIB_0951	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AzCIB_0952	COG1706	bacterial-type flagellum-dependent cell motility
AzCIB_0954	COG1256	bacterial-type flagellum assembly
AzCIB_0958	COG1987	bacterial-type flagellum assembly
AzCIB_0959	COG1338	Plays a role in the flagellum-specific transport system
AzCIB_0960	COG3190	flagellar
AzCIB_0962	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AzCIB_0966	COG1157	protein secretion by the type III secretion system
AzCIB_0968	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AzCIB_0969	COG1766	The M ring may be actively involved in energy transduction
AzCIB_0970	COG3852	Histidine kinase
AzCIB_0972	COG1677	Flagellar hook-basal body complex protein FliE
AzCIB_0973	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
AzCIB_0974	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AzCIB_0978	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AzCIB_0979	COG1334	flagellar protein FlaG
AzCIB_0981	COG3706	GGDEF domain
AzCIB_0981	COG0745	RESPONSE REGULATOR receiver
AzCIB_0982	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AzCIB_0983	COG0508	dehydrogenase complex catalyzes the overall conversion of
AzCIB_0984	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AzCIB_0987	COG4566	intracellular signal transduction
AzCIB_0989	COG0840	transmembrane signaling receptor activity
AzCIB_0992	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AzCIB_0993	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AzCIB_0994	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AzCIB_0995	COG0009	L-threonylcarbamoyladenylate synthase
AzCIB_0997	COG0494	nUDIX hydrolase
AzCIB_0998	COG0419	ATPase involved in DNA repair
AzCIB_1000	COG4302	ethanolamine ammonia-lyase activity
AzCIB_1005	COG0559	Belongs to the binding-protein-dependent transport system permease family
AzCIB_1008	COG0410	ABC transporter
AzCIB_1009	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AzCIB_1010	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AzCIB_1011	COG0318	PFAM AMP-dependent synthetase and ligase
AzCIB_1014	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AzCIB_1015	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AzCIB_1016	COG0022	dehydrogenase e1 component
AzCIB_1016	COG0508	dehydrogenase complex catalyzes the overall conversion of
AzCIB_1018	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AzCIB_1021	COG0288	reversible hydration of carbon dioxide
AzCIB_1027	COG4772	TonB-dependent receptor
AzCIB_1029	COG1944	ATP diphosphatase activity
AzCIB_1031	COG0583	DNA-binding transcription factor activity
AzCIB_1032	COG0318	PFAM AMP-dependent synthetase and ligase
AzCIB_1034	COG2610	gluconate transmembrane transporter activity
AzCIB_1036	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AzCIB_1039	COG1403	HNH endonuclease
AzCIB_1040	COG0386	Belongs to the glutathione peroxidase family
AzCIB_1041	COG0625	glutathione transferase activity
AzCIB_1053	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AzCIB_1054	COG4215	(ABC) transporter
AzCIB_1063	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AzCIB_1065	COG1509	lysine 2,3-aminomutase activity
AzCIB_1066	COG0604	alcohol dehydrogenase
AzCIB_1068	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AzCIB_1069	COG5012	cobalamin binding
AzCIB_1070	COG1607	acyl-coa hydrolase
AzCIB_1071	COG3246	L-lysine catabolic process to acetate
AzCIB_1072	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AzCIB_1072	COG1017	nitric oxide dioxygenase activity
AzCIB_1075	COG3258	Cytochrome c
AzCIB_1076	COG3158	transport of potassium into the cell
AzCIB_1079	COG5006	permease, DMT superfamily
AzCIB_1080	COG3284	Transcriptional regulator
AzCIB_1081	COG1012	belongs to the aldehyde dehydrogenase family
AzCIB_1085	COG1131	(ABC) transporter
AzCIB_1091	COG3284	Transcriptional regulator
AzCIB_1093	COG2414	aldehyde ferredoxin oxidoreductase
AzCIB_1094	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AzCIB_1098	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AzCIB_1099	COG0583	DNA-binding transcription factor activity
AzCIB_1100	COG0702	epimerase
AzCIB_1101	COG3038	cytochrome b561
AzCIB_1102	COG2353	YceI-like domain
AzCIB_1103	COG2353	YceI-like domain
AzCIB_1109	COG0315	cyclic pyranopterin monophosphate synthase activity
AzCIB_1110	COG4783	chaperone-mediated protein folding
AzCIB_1111	COG0425	Belongs to the sulfur carrier protein TusA family
AzCIB_1112	COG0525	valine-tRNA ligase activity
AzCIB_1115	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AzCIB_1116	COG0795	lipopolysaccharide-transporting ATPase activity
AzCIB_1119	COG1959	2 iron, 2 sulfur cluster binding
AzCIB_1120	COG2814	Major facilitator Superfamily
AzCIB_1121	COG0583	DNA-binding transcription factor activity
AzCIB_1122	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AzCIB_1123	COG0564	pseudouridine synthase activity
AzCIB_1125	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AzCIB_1128	COG0798	PFAM Bile acid sodium symporter
AzCIB_1133	COG4974	Belongs to the 'phage' integrase family
AzCIB_1134	COG0517	IMP dehydrogenase activity
AzCIB_1137	COG2963	transposase activity
AzCIB_1141	COG1484	DNA-dependent DNA replication
AzCIB_1146	COG0437	4 iron, 4 sulfur cluster binding
AzCIB_1147	COG0243	molybdopterin cofactor binding
AzCIB_1150	COG3852	Histidine kinase
AzCIB_1151	COG2204	response regulator
AzCIB_1162	COG1473	amidohydrolase
AzCIB_1163	COG0583	DNA-binding transcription factor activity
AzCIB_1164	COG0583	DNA-binding transcription factor activity
AzCIB_1165	COG0509	glycine decarboxylation via glycine cleavage system
AzCIB_1166	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AzCIB_1166	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AzCIB_1168	COG1115	amino acid carrier protein
AzCIB_1169	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AzCIB_1170	COG1113	amino acid transport
AzCIB_1171	COG1760	l-serine dehydratase
AzCIB_1172	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AzCIB_1173	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AzCIB_1175	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AzCIB_1176	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AzCIB_1177	COG0625	glutathione transferase activity
AzCIB_1178	COG3158	transport of potassium into the cell
AzCIB_1179	COG0745	RESPONSE REGULATOR receiver
AzCIB_1180	COG2205	protein histidine kinase activity
AzCIB_1181	COG0604	alcohol dehydrogenase
AzCIB_1182	COG1671	Belongs to the UPF0178 family
AzCIB_1187	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AzCIB_1195	COG0456	acetyltransferase
AzCIB_1196	COG0583	DNA-binding transcription factor activity
AzCIB_1197	COG4948	Mandelate Racemase Muconate Lactonizing
AzCIB_1203	COG4657	Part of a membrane complex involved in electron transport
AzCIB_1204	COG2878	Part of a membrane complex involved in electron transport
AzCIB_1207	COG4659	FMN binding
AzCIB_1209	COG2914	Belongs to the UPF0125 (RnfH) family
AzCIB_1210	COG0625	glutathione transferase activity
AzCIB_1212	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AzCIB_1216	COG0589	response to stress
AzCIB_1217	COG0655	NAD(P)H dehydrogenase (quinone) activity
AzCIB_1221	COG1011	Hydrolase
AzCIB_1231	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AzCIB_1235	COG0583	DNA-binding transcription factor activity
AzCIB_1240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AzCIB_1242	COG0683	leucine binding
AzCIB_1244	COG0559	Belongs to the binding-protein-dependent transport system permease family
AzCIB_1245	COG0411	ABC transporter
AzCIB_1255	COG0674	pyruvate-flavodoxin oxidoreductase activity
AzCIB_1255	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AzCIB_1256	COG1013	pyruvate-flavodoxin oxidoreductase activity
AzCIB_1259	COG0513	Belongs to the DEAD box helicase family
AzCIB_1260	COG1451	nucleotide metabolic process
AzCIB_1261	COG1012	belongs to the aldehyde dehydrogenase family
AzCIB_1262	COG0800	Aldolase
AzCIB_1264	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AzCIB_1266	COG1737	Transcriptional regulator
AzCIB_1267	COG0166	Belongs to the GPI family
AzCIB_1270	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AzCIB_1271	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
AzCIB_1273	COG0535	radical SAM domain protein
AzCIB_1274	COG0435	Glutathione S-transferase
AzCIB_1275	COG2259	Doxx family
AzCIB_1276	COG0400	carboxylic ester hydrolase activity
AzCIB_1279	COG3077	Addiction module antitoxin, RelB DinJ family
AzCIB_1283	COG1115	amino acid carrier protein
AzCIB_1286	COG0402	S-adenosylhomocysteine deaminase activity
AzCIB_1288	COG0517	IMP dehydrogenase activity
AzCIB_1289	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AzCIB_1294	COG0583	DNA-binding transcription factor activity
AzCIB_1295	COG1902	pentaerythritol trinitrate reductase activity
AzCIB_1297	COG5001	Diguanylate cyclase
AzCIB_1297	COG3300	MHYT domain
AzCIB_1299	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AzCIB_1303	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AzCIB_1304	COG1737	Transcriptional regulator
AzCIB_1304	COG0837	glucose binding
AzCIB_1308	COG0582	viral genome integration into host DNA
AzCIB_1320	COG2010	Cytochrome c
AzCIB_1325	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AzCIB_1327	COG5002	protein histidine kinase activity
AzCIB_1328	COG0745	RESPONSE REGULATOR receiver
AzCIB_1329	COG2176	DNA-directed DNA polymerase activity
AzCIB_1329	COG5002	protein histidine kinase activity
AzCIB_1330	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AzCIB_1340	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AzCIB_1346	COG0514	ATP-dependent DNA helicase (RecQ)
AzCIB_1354	COG1397	ADP-ribosylglycohydrolase
AzCIB_1375	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AzCIB_1377	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AzCIB_1411	COG0129	dihydroxy-acid dehydratase activity
AzCIB_1417	COG1525	nuclease
AzCIB_1426	COG0420	3'-5' exonuclease activity
AzCIB_1440	COG1484	DNA-dependent DNA replication
AzCIB_1441	COG4584	PFAM Integrase catalytic
AzCIB_1441	COG2390	Transcriptional regulator
AzCIB_1446	COG3012	SEC-C Motif Domain Protein
AzCIB_1448	COG3436	PFAM IS66 Orf2 family protein
AzCIB_1449	COG4372	Transposase
AzCIB_1450	COG3012	SEC-C Motif Domain Protein
AzCIB_1452	COG3039	Transposase
AzCIB_1460	COG1960	acyl-CoA dehydrogenase activity
AzCIB_1463	COG2086	electron transfer activity
AzCIB_1466	COG1028	Short-chain dehydrogenase reductase Sdr
AzCIB_1468	COG1024	Enoyl-CoA hydratase
AzCIB_1471	COG1902	pentaerythritol trinitrate reductase activity
AzCIB_1471	COG0446	pyridine nucleotide-disulphide oxidoreductase
AzCIB_1472	COG1053	succinate dehydrogenase
AzCIB_1473	COG0477	Major facilitator Superfamily
AzCIB_1474	COG1902	pentaerythritol trinitrate reductase activity
AzCIB_1477	COG1028	Short-chain dehydrogenase reductase Sdr
AzCIB_1479	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AzCIB_1479	COG3608	succinylglutamate desuccinylase aspartoacylase
AzCIB_1481	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AzCIB_1485	COG1960	acyl-CoA dehydrogenase activity
AzCIB_1486	COG1960	acyl-CoA dehydrogenase activity
AzCIB_1488	COG1024	Enoyl-CoA hydratase
AzCIB_1491	COG0318	PFAM AMP-dependent synthetase and ligase
AzCIB_1494	COG2070	2-Nitropropane dioxygenase
AzCIB_1498	COG2081	HI0933 family
AzCIB_1499	COG3668	Plasmid stabilization system
AzCIB_1502	COG1012	belongs to the aldehyde dehydrogenase family
AzCIB_1505	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AzCIB_1508	COG4569	acetaldehyde dehydrogenase (acetylating) activity
AzCIB_1509	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AzCIB_1512	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AzCIB_1513	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AzCIB_1516	COG1024	Enoyl-CoA hydratase
AzCIB_1521	COG0446	pyridine nucleotide-disulphide oxidoreductase
AzCIB_1521	COG1902	pentaerythritol trinitrate reductase activity
AzCIB_1522	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AzCIB_1527	COG1024	Enoyl-CoA hydratase
AzCIB_1530	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AzCIB_1532	COG1960	acyl-CoA dehydrogenase activity
AzCIB_1536	COG1960	acyl-CoA dehydrogenase activity
AzCIB_1537	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AzCIB_1540	COG2181	nitrate reductase activity
AzCIB_1540	COG0247	lactate metabolic process
AzCIB_1545	COG0488	(ABC) transporter
AzCIB_1547	COG2259	Doxx family
AzCIB_1553	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AzCIB_1555	COG0306	phosphate transporter
AzCIB_1557	COG0302	gtp cyclohydrolase
AzCIB_1559	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AzCIB_1563	COG4681	YaeQ
AzCIB_1565	COG1253	flavin adenine dinucleotide binding
AzCIB_1566	COG1012	belongs to the aldehyde dehydrogenase family
AzCIB_1570	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AzCIB_1572	COG0477	Major facilitator Superfamily
AzCIB_1573	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AzCIB_1576	COG2205	protein histidine kinase activity
AzCIB_1576	COG0784	Response regulator, receiver
AzCIB_1578	COG0523	cobalamin synthesis protein
AzCIB_1579	COG2879	small protein
AzCIB_1580	COG1966	Carbon starvation protein
AzCIB_1584	COG0410	ABC transporter
AzCIB_1593	COG2133	pyrroloquinoline quinone binding
AzCIB_1598	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AzCIB_1601	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AzCIB_1614	COG1024	Enoyl-CoA hydratase
AzCIB_1615	COG1028	Short-chain dehydrogenase reductase Sdr
AzCIB_1620	COG0411	ABC transporter
AzCIB_1622	COG2814	Major facilitator Superfamily
AzCIB_1629	COG2363	Small membrane protein
AzCIB_1661	COG3851	Histidine kinase
AzCIB_1662	COG2197	response regulator
AzCIB_1664	COG0789	Transcriptional regulator
AzCIB_1667	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AzCIB_1669	COG0789	Transcriptional regulator
AzCIB_1676	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AzCIB_1677	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AzCIB_1681	COG0789	Transcriptional regulator
AzCIB_1707	COG3437	response regulator, receiver
AzCIB_1711	COG2226	methyltransferase
AzCIB_1714	COG0723	plastoquinol--plastocyanin reductase activity
AzCIB_1724	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AzCIB_1725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AzCIB_1728	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
AzCIB_1741	COG3591	Belongs to the peptidase S1B family
AzCIB_1751	COG2129	metallophosphoesterase
AzCIB_1760	COG0024	Methionine aminopeptidase
AzCIB_1764	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AzCIB_1767	COG3047	cAMP biosynthetic process
AzCIB_1769	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AzCIB_1772	COG1196	nuclear chromosome segregation
AzCIB_1773	COG1280	lysine exporter protein (LysE YggA)
AzCIB_1780	COG1802	Transcriptional regulator
AzCIB_1781	COG0183	Belongs to the thiolase family
AzCIB_1785	COG1960	acyl-CoA dehydrogenase activity
AzCIB_1788	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AzCIB_1791	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AzCIB_1807	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AzCIB_1808	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AzCIB_1810	COG0437	4 iron, 4 sulfur cluster binding
AzCIB_1811	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AzCIB_1819	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AzCIB_1821	COG0519	Catalyzes the synthesis of GMP from XMP
AzCIB_1821	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AzCIB_1824	COG2914	Belongs to the UPF0125 (RnfH) family
AzCIB_1826	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AzCIB_1827	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AzCIB_1828	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AzCIB_1829	COG0601	transmembrane transport
AzCIB_1846	COG3944	biosynthesis protein
AzCIB_1852	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AzCIB_1853	COG0542	response to heat
AzCIB_1855	COG0314	molybdopterin synthase activity
AzCIB_1856	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AzCIB_1857	COG0303	'Molybdopterin
AzCIB_1858	COG1763	Mo-molybdopterin cofactor biosynthetic process
AzCIB_1860	COG1199	ATP-dependent helicase activity
AzCIB_1861	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AzCIB_1862	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AzCIB_1863	COG0508	dehydrogenase complex catalyzes the overall conversion of
AzCIB_1864	COG0567	Dehydrogenase, E1 component
AzCIB_1865	COG0372	Belongs to the citrate synthase family
AzCIB_1866	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AzCIB_1867	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AzCIB_1868	COG1053	succinate dehydrogenase
AzCIB_1871	COG2188	Transcriptional regulator
AzCIB_1872	COG0039	L-malate dehydrogenase activity
AzCIB_1874	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AzCIB_1877	COG1840	ABC-type Fe3 transport system, periplasmic component
AzCIB_1880	COG1178	ABC-type Fe3 transport system permease component
AzCIB_1882	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AzCIB_1883	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AzCIB_1884	COG0167	dihydroorotate dehydrogenase activity
AzCIB_1886	COG2878	Part of a membrane complex involved in electron transport
AzCIB_1887	COG4656	Part of a membrane complex involved in electron transport
AzCIB_1888	COG4658	electron transport chain
AzCIB_1891	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AzCIB_1893	COG0745	RESPONSE REGULATOR receiver
AzCIB_1897	COG0326	Molecular chaperone. Has ATPase activity
AzCIB_1902	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AzCIB_1910	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AzCIB_1920	COG0045	succinate-CoA ligase (ADP-forming) activity
AzCIB_1920	COG1042	CoA-binding domain protein
AzCIB_1920	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AzCIB_1922	COG0210	DNA helicase
AzCIB_1923	COG2837	iron assimilation
AzCIB_1925	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AzCIB_1930	COG2989	Protein conserved in bacteria
AzCIB_1931	COG3108	Peptidase M15
AzCIB_1932	COG1522	sequence-specific DNA binding
AzCIB_1937	COG0183	Belongs to the thiolase family
AzCIB_1938	COG1250	3-hydroxyacyl-CoA dehydrogenase
AzCIB_1939	COG1024	Enoyl-CoA hydratase
AzCIB_1942	COG1960	acyl-CoA dehydrogenase activity
AzCIB_1943	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AzCIB_1945	COG1846	Transcriptional regulator
AzCIB_1947	COG0318	PFAM AMP-dependent synthetase and ligase
AzCIB_1948	COG1024	Enoyl-CoA hydratase
AzCIB_1950	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AzCIB_1951	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AzCIB_1952	COG1942	4-Oxalocrotonate Tautomerase
AzCIB_1957	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AzCIB_1957	COG2273	Hydrolase Family 16
AzCIB_1963	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AzCIB_1971	COG0791	NLP P60 protein
AzCIB_1973	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AzCIB_1974	COG0148	phosphopyruvate hydratase activity
AzCIB_1975	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AzCIB_1976	COG0504	CTP synthase activity
AzCIB_1985	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AzCIB_1985	COG0047	phosphoribosylformylglycinamidine synthase activity
AzCIB_1986	COG0671	phosphoesterase, PA-phosphatase related
AzCIB_1988	COG0463	Glycosyl transferase, family 2
AzCIB_1990	COG0671	phosphoesterase, PA-phosphatase related
AzCIB_1993	COG1196	nuclear chromosome segregation
AzCIB_1993	COG0739	heme binding
AzCIB_1993	COG0741	lytic transglycosylase activity
AzCIB_1994	COG0446	pyridine nucleotide-disulphide oxidoreductase
AzCIB_1994	COG1902	pentaerythritol trinitrate reductase activity
AzCIB_1996	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AzCIB_1998	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AzCIB_2003	COG1136	(ABC) transporter
AzCIB_2005	COG1620	l-lactate permease
AzCIB_2010	COG1846	Transcriptional regulator
AzCIB_2013	COG1127	ABC transporter
AzCIB_2014	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AzCIB_2015	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AzCIB_2016	COG2169	Transcriptional regulator
AzCIB_2016	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AzCIB_2017	COG3530	Putative quorum-sensing-regulated virulence factor
AzCIB_2018	COG2195	Cleaves the N-terminal amino acid of tripeptides
AzCIB_2020	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AzCIB_2021	COG0577	efflux transmembrane transporter activity
AzCIB_2021	COG1136	(ABC) transporter
AzCIB_2024	COG1309	transcriptional regulator
AzCIB_2027	COG0477	Major facilitator Superfamily
AzCIB_2028	COG1573	uracil-dna glycosylase
AzCIB_2030	COG1214	PFAM Peptidase M22, glycoprotease
AzCIB_2032	COG0745	RESPONSE REGULATOR receiver
AzCIB_2034	COG2917	probably involved in intracellular septation
AzCIB_2035	COG2350	Protein conserved in bacteria
AzCIB_2036	COG0271	Belongs to the BolA IbaG family
AzCIB_2037	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AzCIB_2038	COG1960	acyl-CoA dehydrogenase activity
AzCIB_2041	COG1309	transcriptional regulator
AzCIB_2042	COG0084	hydrolase, TatD family'
AzCIB_2046	COG1127	ABC transporter
AzCIB_2047	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AzCIB_2048	COG0248	Ppx GppA phosphatase
AzCIB_2049	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AzCIB_2051	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AzCIB_2058	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AzCIB_2059	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AzCIB_2061	COG1355	regulation of microtubule-based process
AzCIB_2062	COG3885	ferrous iron binding
AzCIB_2062	COG2078	PFAM AMMECR1 domain protein
AzCIB_2063	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AzCIB_2065	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AzCIB_2072	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AzCIB_2073	COG4208	sulfate ABC transporter
AzCIB_2074	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AzCIB_2075	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AzCIB_2079	COG2353	YceI-like domain
AzCIB_2082	COG2198	Histidine kinase
AzCIB_2082	COG0643	Histidine kinase
AzCIB_2083	COG2201	protein-glutamate methylesterase activity
AzCIB_2085	COG1611	Belongs to the LOG family
AzCIB_2095	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AzCIB_2096	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AzCIB_2098	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AzCIB_2106	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AzCIB_2109	COG4628	conserved protein (DUF2132)
AzCIB_2113	COG1404	Belongs to the peptidase S8 family
AzCIB_2133	COG1760	l-serine dehydratase
AzCIB_2134	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AzCIB_2136	COG3005	denitrification pathway
AzCIB_2140	COG0477	Major facilitator Superfamily
AzCIB_2142	COG3842	ATPase activity
AzCIB_2144	COG1176	ABC-type spermidine putrescine transport system, permease component I
AzCIB_2151	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AzCIB_2153	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AzCIB_2154	COG0328	RNA-DNA hybrid ribonuclease activity
AzCIB_2156	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AzCIB_2157	COG3706	GGDEF domain
AzCIB_2157	COG4251	negative regulation of phosphorylation
AzCIB_2157	COG5001	Diguanylate cyclase
AzCIB_2157	COG2203	Gaf domain
AzCIB_2158	COG0741	lytic transglycosylase activity
AzCIB_2158	COG1388	LysM domain
AzCIB_2159	COG4172	Belongs to the ABC transporter superfamily
AzCIB_2161	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AzCIB_2162	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AzCIB_2166	COG0534	Mate efflux family protein
AzCIB_2168	COG2205	protein histidine kinase activity
AzCIB_2168	COG5002	protein histidine kinase activity
AzCIB_2168	COG0784	Response regulator, receiver
AzCIB_2169	COG0587	DNA-directed DNA polymerase activity
AzCIB_2170	COG0745	RESPONSE REGULATOR receiver
AzCIB_2170	COG3706	GGDEF domain
AzCIB_2181	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AzCIB_2182	COG1140	nitrate reductase beta subunit
AzCIB_2183	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AzCIB_2184	COG2181	nitrate reductase activity
AzCIB_2185	COG3850	Histidine kinase
AzCIB_2186	COG2197	response regulator
AzCIB_2188	COG4263	nitrous-oxide reductase activity
AzCIB_2199	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AzCIB_2200	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AzCIB_2201	COG0560	Phosphoserine phosphatase
AzCIB_2202	COG2866	Carboxypeptidase
AzCIB_2203	COG3022	response to hydroperoxide
AzCIB_2205	COG0156	8-amino-7-oxononanoate synthase activity
AzCIB_2206	COG2267	carboxylic ester hydrolase activity
AzCIB_2207	COG2226	methyltransferase
AzCIB_2208	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AzCIB_2209	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AzCIB_2211	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AzCIB_2212	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AzCIB_2213	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AzCIB_2214	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AzCIB_2215	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AzCIB_2219	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AzCIB_2220	COG0575	Belongs to the CDS family
AzCIB_2221	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AzCIB_2222	COG0233	cytoplasmic translational termination
AzCIB_2223	COG0528	UMP kinase activity
AzCIB_2224	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AzCIB_2225	COG0052	Belongs to the universal ribosomal protein uS2 family
AzCIB_2226	COG0024	Methionine aminopeptidase
AzCIB_2227	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AzCIB_2228	COG2862	Uncharacterized protein family, UPF0114
AzCIB_2230	COG2151	metal-sulfur cluster biosynthetic enzyme
AzCIB_2247	COG3237	CsbD-like
AzCIB_2250	COG2982	Protein involved in outer membrane biogenesis
AzCIB_2251	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AzCIB_2254	COG3218	ABC-type transport auxiliary lipoprotein component
AzCIB_2256	COG4585	Histidine kinase
AzCIB_2257	COG2197	response regulator
AzCIB_2262	COG0484	heat shock protein binding
AzCIB_2272	COG0628	permease
AzCIB_2278	COG3459	Glycosyltransferase 36 associated
AzCIB_2280	COG2823	Periplasmic or secreted lipoprotein
AzCIB_2281	COG4575	ribosome binding
AzCIB_2288	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AzCIB_2294	COG0784	Response regulator, receiver
AzCIB_2294	COG3437	response regulator, receiver
AzCIB_2295	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AzCIB_2314	COG0559	Belongs to the binding-protein-dependent transport system permease family
AzCIB_2316	COG1609	Transcriptional regulator
AzCIB_2318	COG0277	FAD linked oxidase domain protein
AzCIB_2319	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AzCIB_2320	COG1012	belongs to the aldehyde dehydrogenase family
AzCIB_2323	COG2226	methyltransferase
AzCIB_2325	COG0659	secondary active sulfate transmembrane transporter activity
AzCIB_2329	COG1595	DNA-templated transcription, initiation
AzCIB_2331	COG2391	methyltransferase activity
AzCIB_2333	COG1215	transferase activity, transferring glycosyl groups
AzCIB_2339	COG4191	Histidine kinase
AzCIB_2340	COG2201	protein-glutamate methylesterase activity
AzCIB_2342	COG0840	transmembrane signaling receptor activity
AzCIB_2342	COG3290	protein histidine kinase activity
AzCIB_2348	COG3852	Histidine kinase
AzCIB_2352	COG4191	Histidine kinase
AzCIB_2352	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AzCIB_2353	COG1100	Small GTP-binding protein
AzCIB_2354	COG2204	response regulator
AzCIB_2355	COG2204	response regulator
AzCIB_2361	COG2902	Dehydrogenase
AzCIB_2362	COG1012	belongs to the aldehyde dehydrogenase family
AzCIB_2366	COG1012	belongs to the aldehyde dehydrogenase family
AzCIB_2367	COG4447	cellulose binding
AzCIB_2371	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AzCIB_2372	COG0589	response to stress
AzCIB_2374	COG2181	nitrate reductase activity
AzCIB_2374	COG0247	lactate metabolic process
AzCIB_2378	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AzCIB_2385	COG2095	MarC family integral membrane protein
AzCIB_2388	COG0583	DNA-binding transcription factor activity
AzCIB_2392	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AzCIB_2394	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AzCIB_2396	COG2111	Na H antiporter
AzCIB_2396	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AzCIB_2397	COG1006	Multisubunit Na H antiporter MnhC subunit
AzCIB_2398	COG0651	ATP synthesis coupled electron transport
AzCIB_2399	COG1863	multisubunit Na H antiporter MnhE subunit
AzCIB_2400	COG2212	antiporter activity
AzCIB_2404	COG3474	cytochrome
AzCIB_2408	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AzCIB_2409	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AzCIB_2412	COG2009	succinate dehydrogenase
AzCIB_2413	COG0776	regulation of translation
AzCIB_2417	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AzCIB_2421	COG2814	Major facilitator Superfamily
AzCIB_2425	COG1028	Short-chain dehydrogenase reductase Sdr
AzCIB_2426	COG1024	Enoyl-CoA hydratase
AzCIB_2434	COG1250	3-hydroxyacyl-CoA dehydrogenase
AzCIB_2435	COG0179	Fumarylacetoacetate (FAA) hydrolase
AzCIB_2442	COG2223	nitrite transmembrane transporter activity
AzCIB_2443	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AzCIB_2445	COG0179	Fumarylacetoacetate (FAA) hydrolase
AzCIB_2446	COG1028	Short-chain dehydrogenase reductase Sdr
AzCIB_2457	COG2086	electron transfer activity
AzCIB_2459	COG0583	DNA-binding transcription factor activity
AzCIB_2462	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AzCIB_2465	COG0204	Acyl-transferase
AzCIB_2466	COG1028	Short-chain dehydrogenase reductase Sdr
AzCIB_2468	COG1063	alcohol dehydrogenase
AzCIB_2469	COG1960	acyl-CoA dehydrogenase activity
AzCIB_2470	COG1024	Enoyl-CoA hydratase
AzCIB_2471	COG2271	Major facilitator Superfamily
AzCIB_2475	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AzCIB_2483	COG1846	Transcriptional regulator
AzCIB_2485	COG3012	SEC-C Motif Domain Protein
AzCIB_2486	COG4372	Transposase
AzCIB_2487	COG3436	PFAM IS66 Orf2 family protein
AzCIB_2491	COG1764	response to oxidative stress
AzCIB_2494	COG1024	Enoyl-CoA hydratase
AzCIB_2495	COG1028	Short-chain dehydrogenase reductase Sdr
AzCIB_2496	COG1024	Enoyl-CoA hydratase
AzCIB_2498	COG2130	NADP-dependent
AzCIB_2499	COG2130	NADP-dependent
AzCIB_2500	COG1960	acyl-CoA dehydrogenase activity
AzCIB_2502	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AzCIB_2504	COG1960	acyl-CoA dehydrogenase activity
AzCIB_2505	COG1024	Enoyl-CoA hydratase
AzCIB_2507	COG1960	acyl-CoA dehydrogenase activity
AzCIB_2509	COG2030	dehydratase
AzCIB_2510	COG1028	Short-chain dehydrogenase reductase Sdr
AzCIB_2511	COG1028	Short-chain dehydrogenase reductase Sdr
AzCIB_2512	COG1024	Enoyl-CoA hydratase
AzCIB_2516	COG0427	acetyl-CoA hydrolase
AzCIB_2517	COG1024	Enoyl-CoA hydratase
AzCIB_2517	COG1250	3-hydroxyacyl-CoA dehydrogenase
AzCIB_2519	COG0183	Belongs to the thiolase family
AzCIB_2530	COG0302	gtp cyclohydrolase
AzCIB_2532	COG1024	Enoyl-CoA hydratase
AzCIB_2533	COG1960	acyl-CoA dehydrogenase activity
AzCIB_2534	COG1960	acyl-CoA dehydrogenase activity
AzCIB_2536	COG2124	cytochrome p450
AzCIB_2537	COG1028	Short-chain dehydrogenase reductase Sdr
AzCIB_2541	COG1028	Short-chain dehydrogenase reductase Sdr
AzCIB_2542	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AzCIB_2548	COG1233	COG1233 Phytoene dehydrogenase and related
AzCIB_2553	COG3039	Transposase
AzCIB_2554	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AzCIB_2563	COG1192	Involved in chromosome partitioning
AzCIB_2585	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AzCIB_2593	COG2003	Belongs to the UPF0758 family
AzCIB_2602	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AzCIB_2603	COG0732	type I restriction modification DNA specificity domain
AzCIB_2604	COG4804	nuclease activity
AzCIB_2614	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AzCIB_2617	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AzCIB_2618	COG1185	polyribonucleotide nucleotidyltransferase activity
AzCIB_2619	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AzCIB_2620	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AzCIB_2621	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AzCIB_2622	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AzCIB_2623	COG0195	Participates in both transcription termination and antitermination
AzCIB_2623	COG2251	uridine kinase activity
AzCIB_2624	COG0779	Required for maturation of 30S ribosomal subunits
AzCIB_2626	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AzCIB_2627	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AzCIB_2628	COG0180	Tryptophanyl-tRNA synthetase
AzCIB_2629	COG1994	Peptidase M50
AzCIB_2630	COG0009	L-threonylcarbamoyladenylate synthase
AzCIB_2631	COG0613	PHP domain protein
AzCIB_2632	COG0509	glycine decarboxylation via glycine cleavage system
AzCIB_2633	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AzCIB_2633	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AzCIB_2635	COG1215	transferase activity, transferring glycosyl groups
AzCIB_2636	COG0583	DNA-binding transcription factor activity
AzCIB_2639	COG0508	dehydrogenase complex catalyzes the overall conversion of
AzCIB_2641	COG0488	(ABC) transporter
AzCIB_2642	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AzCIB_2643	COG3263	regulation of cellular component size
AzCIB_2645	COG0577	efflux transmembrane transporter activity
AzCIB_2646	COG1136	(ABC) transporter
AzCIB_2649	COG5002	protein histidine kinase activity
AzCIB_2649	COG5001	Diguanylate cyclase
AzCIB_2649	COG3447	MASE1 domain protein
AzCIB_2650	COG1562	ergosterol biosynthetic process
AzCIB_2652	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AzCIB_2653	COG4181	ATPase activity
AzCIB_2656	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AzCIB_2657	COG2204	response regulator
AzCIB_2658	COG4191	Histidine kinase
AzCIB_2660	COG1132	(ABC) transporter
AzCIB_2664	COG1042	CoA-binding domain protein
AzCIB_2664	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AzCIB_2664	COG0045	succinate-CoA ligase (ADP-forming) activity
AzCIB_2666	COG2183	response to ionizing radiation
AzCIB_2667	COG1393	Belongs to the ArsC family
AzCIB_2669	COG0850	regulation of cytokinetic process
AzCIB_2671	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AzCIB_2673	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AzCIB_2674	COG3657	addiction module killer protein
AzCIB_2675	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AzCIB_2676	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AzCIB_2676	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AzCIB_2677	COG4585	Histidine kinase
AzCIB_2678	COG2197	response regulator
AzCIB_2680	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AzCIB_2685	COG0574	Belongs to the PEP-utilizing enzyme family
AzCIB_2685	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AzCIB_2686	COG0517	IMP dehydrogenase activity
AzCIB_2688	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AzCIB_2691	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AzCIB_2695	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AzCIB_2699	COG2816	NAD+ diphosphatase activity
AzCIB_2700	COG0450	alkyl hydroperoxide reductase
AzCIB_2701	COG3634	alkyl hydroperoxide reductase activity
AzCIB_2706	COG2205	protein histidine kinase activity
AzCIB_2706	COG2202	Pas domain
AzCIB_2714	COG2204	response regulator
AzCIB_2716	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AzCIB_2719	COG1538	Outer membrane efflux protein
AzCIB_2720	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AzCIB_2724	COG0515	serine threonine protein kinase
AzCIB_2725	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AzCIB_2728	COG1960	acyl-CoA dehydrogenase activity
AzCIB_2730	COG0183	Belongs to the thiolase family
AzCIB_2731	COG1024	Enoyl-CoA hydratase
AzCIB_2732	COG0318	PFAM AMP-dependent synthetase and ligase
AzCIB_2736	COG0411	ABC transporter
AzCIB_2738	COG1309	transcriptional regulator
AzCIB_2741	COG5002	protein histidine kinase activity
AzCIB_2744	COG2151	metal-sulfur cluster biosynthetic enzyme
AzCIB_2746	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AzCIB_2747	COG0719	Fe-S assembly protein
AzCIB_2748	COG0396	ATPase activity
AzCIB_2749	COG0719	Fe-S assembly protein
AzCIB_2750	COG1067	ATP-dependent peptidase activity
AzCIB_2751	COG1335	isochorismatase
AzCIB_2756	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AzCIB_2758	COG1196	nuclear chromosome segregation
AzCIB_2760	COG2171	N-acyltransferase activity
AzCIB_2762	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AzCIB_2764	COG0784	Response regulator, receiver
AzCIB_2766	COG0633	Ferredoxin
AzCIB_2767	COG0443	Heat shock 70 kDa protein
AzCIB_2768	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AzCIB_2770	COG0822	iron-sulfur transferase activity
AzCIB_2771	COG1104	cysteine desulfurase activity
AzCIB_2772	COG1104	cysteine desulfurase activity
AzCIB_2774	COG1045	serine acetyltransferase
AzCIB_2777	COG0513	Belongs to the DEAD box helicase family
AzCIB_2781	COG0322	excinuclease ABC activity
AzCIB_2782	COG1472	Belongs to the glycosyl hydrolase 3 family
AzCIB_2783	COG0736	holo-[acyl-carrier-protein] synthase activity
AzCIB_2784	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AzCIB_2785	COG1381	Involved in DNA repair and RecF pathway recombination
AzCIB_2786	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AzCIB_2787	COG0571	ribonuclease III activity
AzCIB_2789	COG0681	Belongs to the peptidase S26 family
AzCIB_2790	COG0481	GTPase activity
AzCIB_2792	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AzCIB_2797	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AzCIB_2799	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AzCIB_2800	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AzCIB_2803	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AzCIB_2804	COG0416	fatty acid biosynthetic process
AzCIB_2805	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AzCIB_2806	COG1399	metal-binding, possibly nucleic acid-binding protein
AzCIB_2807	COG0424	maF-like protein
AzCIB_2808	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AzCIB_2809	COG0546	phosphoglycolate phosphatase activity
AzCIB_2810	COG0564	pseudouridine synthase activity
AzCIB_2811	COG1530	ribonuclease E activity
AzCIB_2812	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AzCIB_2813	COG0556	nucleotide-excision repair
AzCIB_2815	COG1067	ATP-dependent peptidase activity
AzCIB_2817	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AzCIB_2820	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AzCIB_2821	COG1473	amidohydrolase
AzCIB_2824	COG0084	hydrolase, TatD family'
AzCIB_2827	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AzCIB_2828	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AzCIB_2833	COG0590	tRNA wobble adenosine to inosine editing
AzCIB_2845	COG0243	molybdopterin cofactor binding
AzCIB_2846	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AzCIB_2847	COG3327	negative regulation of DNA-templated transcription, initiation
AzCIB_2851	COG2814	Major facilitator Superfamily
AzCIB_2852	COG2814	Major facilitator Superfamily
AzCIB_2854	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AzCIB_2855	COG1013	pyruvate-flavodoxin oxidoreductase activity
AzCIB_2856	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AzCIB_2856	COG0674	pyruvate-flavodoxin oxidoreductase activity
AzCIB_2857	COG1846	Transcriptional regulator
AzCIB_2858	COG4628	conserved protein (DUF2132)
AzCIB_2864	COG1012	belongs to the aldehyde dehydrogenase family
AzCIB_2873	COG1714	RDD family
AzCIB_2878	COG2814	Major facilitator Superfamily
AzCIB_2879	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AzCIB_2881	COG1538	Outer membrane efflux protein
AzCIB_2882	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AzCIB_2883	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AzCIB_2885	COG0242	peptide deformylase activity
AzCIB_2887	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AzCIB_2887	COG1013	pyruvate-flavodoxin oxidoreductase activity
AzCIB_2887	COG0674	pyruvate-flavodoxin oxidoreductase activity
AzCIB_2887	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AzCIB_2888	COG0776	regulation of translation
AzCIB_2889	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AzCIB_2890	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AzCIB_2891	COG0740	serine-type endopeptidase activity
AzCIB_2892	COG0544	peptidyl-prolyl cis-trans isomerase activity
AzCIB_2893	COG2766	serine protein kinase
AzCIB_2895	COG2719	SpoVR family
AzCIB_2896	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AzCIB_2896	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AzCIB_2898	COG0697	spore germination
AzCIB_2902	COG0436	Aminotransferase
AzCIB_2904	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AzCIB_2905	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AzCIB_2908	COG0791	NLP P60 protein
AzCIB_2911	COG2814	Major facilitator Superfamily
AzCIB_2915	COG1250	3-hydroxyacyl-CoA dehydrogenase
AzCIB_2916	COG0183	Belongs to the thiolase family
AzCIB_2920	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AzCIB_2921	COG3012	SEC-C Motif Domain Protein
AzCIB_2928	COG3012	SEC-C Motif Domain Protein
AzCIB_2928	COG3318	Belongs to the UPF0149 family
AzCIB_2929	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AzCIB_2931	COG0254	rRNA binding
AzCIB_2933	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AzCIB_2934	COG0501	Belongs to the peptidase M48B family
AzCIB_2935	COG1162	GTPase activity
AzCIB_2936	COG0183	Belongs to the thiolase family
AzCIB_2938	COG3384	dioxygenase
AzCIB_2941	COG1490	D-aminoacyl-tRNA deacylase activity
AzCIB_2952	COG1027	Aspartate ammonia-lyase
AzCIB_2956	COG1132	(ABC) transporter
AzCIB_2961	COG1012	belongs to the aldehyde dehydrogenase family
AzCIB_2964	COG2409	Drug exporters of the RND superfamily
AzCIB_2977	COG3259	Nickel-dependent hydrogenase
AzCIB_2978	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
AzCIB_2979	COG3383	formate dehydrogenase (NAD+) activity
AzCIB_2980	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AzCIB_2981	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AzCIB_2983	COG1007	ATP synthesis coupled electron transport
AzCIB_2986	COG0713	ATP synthesis coupled electron transport
AzCIB_2988	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AzCIB_2989	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AzCIB_2990	COG1034	ATP synthesis coupled electron transport
AzCIB_2993	COG0649	NAD binding
AzCIB_2994	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AzCIB_2995	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AzCIB_2996	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AzCIB_2998	COG0149	triose-phosphate isomerase activity
AzCIB_2999	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AzCIB_3000	COG0573	inorganic phosphate transmembrane transporter activity
AzCIB_3001	COG0573	inorganic phosphate transmembrane transporter activity
AzCIB_3002	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AzCIB_3003	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AzCIB_3005	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AzCIB_3006	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AzCIB_3008	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AzCIB_3009	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AzCIB_3010	COG0505	Belongs to the CarA family
AzCIB_3011	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AzCIB_3012	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AzCIB_3013	COG0735	belongs to the Fur family
AzCIB_3014	COG0497	DNA recombination
AzCIB_3015	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AzCIB_3016	COG1420	regulation of RNA biosynthetic process
AzCIB_3017	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AzCIB_3019	COG0515	serine threonine protein kinase
AzCIB_3019	COG2815	serine threonine protein kinase
AzCIB_3020	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AzCIB_3021	COG0443	Heat shock 70 kDa protein
AzCIB_3022	COG0484	heat shock protein binding
AzCIB_3023	COG0215	cysteine-tRNA ligase activity
AzCIB_3027	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AzCIB_3028	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AzCIB_3033	COG0285	dihydrofolate synthase activity
AzCIB_3034	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AzCIB_3035	COG0159	tryptophan synthase activity
AzCIB_3036	COG0133	tryptophan synthase activity
AzCIB_3037	COG0135	phosphoribosylanthranilate isomerase activity
AzCIB_3038	COG0101	tRNA pseudouridine synthase activity
AzCIB_3042	COG0473	3-isopropylmalate dehydrogenase activity
AzCIB_3043	COG0066	3-isopropylmalate dehydratase activity
AzCIB_3044	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AzCIB_3045	COG4783	chaperone-mediated protein folding
AzCIB_3046	COG2814	Major facilitator Superfamily
AzCIB_3047	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AzCIB_3048	COG0440	acetolactate synthase activity
AzCIB_3049	COG0028	Belongs to the TPP enzyme family
AzCIB_3050	COG0318	PFAM AMP-dependent synthetase and ligase
AzCIB_3054	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AzCIB_3055	COG1250	3-hydroxyacyl-CoA dehydrogenase
AzCIB_3056	COG0277	FAD linked oxidase domain protein
AzCIB_3057	COG1752	Esterase of the alpha-beta hydrolase superfamily
AzCIB_3058	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AzCIB_3059	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
AzCIB_3061	COG1028	Short-chain dehydrogenase reductase Sdr
AzCIB_3062	COG3243	poly(R)-hydroxyalkanoic acid synthase
AzCIB_3065	COG0564	pseudouridine synthase activity
AzCIB_3069	COG2951	lytic endotransglycosylase activity
AzCIB_3070	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AzCIB_3071	COG0288	reversible hydration of carbon dioxide
AzCIB_3072	COG0659	secondary active sulfate transmembrane transporter activity
AzCIB_3073	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AzCIB_3074	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AzCIB_3076	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AzCIB_3077	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AzCIB_3078	COG1674	ftsk spoiiie
AzCIB_3080	COG0492	ferredoxin-NADP+ reductase activity
AzCIB_3081	COG2840	Smr protein MutS2
AzCIB_3082	COG0347	Belongs to the P(II) protein family
AzCIB_3083	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AzCIB_3083	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AzCIB_3088	COG2217	Heavy metal translocating P-type atpase
AzCIB_3091	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AzCIB_3092	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AzCIB_3097	COG3243	poly(R)-hydroxyalkanoic acid synthase
AzCIB_3098	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AzCIB_3106	COG3278	Belongs to the heme-copper respiratory oxidase family
AzCIB_3108	COG2217	Heavy metal translocating P-type atpase
AzCIB_3110	COG0494	nUDIX hydrolase
AzCIB_3112	COG2972	Histidine kinase
AzCIB_3112	COG0745	RESPONSE REGULATOR receiver
AzCIB_3121	COG1666	GTP binding
AzCIB_3122	COG3123	guanosine phosphorylase activity
AzCIB_3124	COG0137	argininosuccinate synthase activity
AzCIB_3125	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AzCIB_3126	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AzCIB_3128	COG0268	Binds directly to 16S ribosomal RNA
AzCIB_3130	COG1881	PFAM PEBP family protein
AzCIB_3131	COG0405	Gamma-glutamyltransferase
AzCIB_3133	COG0205	6-phosphofructokinase activity
AzCIB_3134	COG0563	adenylate kinase activity
AzCIB_3135	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AzCIB_3136	COG2835	tetraacyldisaccharide 4'-kinase activity
AzCIB_3137	COG1663	tetraacyldisaccharide 4'-kinase activity
AzCIB_3138	COG0848	biopolymer transport protein
AzCIB_3139	COG0811	peptide transport
AzCIB_3140	COG1570	exodeoxyribonuclease VII activity
AzCIB_3141	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AzCIB_3142	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AzCIB_3149	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AzCIB_3150	COG4208	sulfate ABC transporter
AzCIB_3151	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AzCIB_3152	COG0583	DNA-binding transcription factor activity
AzCIB_3153	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AzCIB_3155	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AzCIB_3156	COG0643	Histidine kinase
AzCIB_3156	COG2198	Histidine kinase
AzCIB_3157	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AzCIB_3158	COG0745	RESPONSE REGULATOR receiver
AzCIB_3159	COG0835	chemotaxis
AzCIB_3159	COG0784	Response regulator, receiver
AzCIB_3160	COG0784	Response regulator, receiver
AzCIB_3160	COG0835	chemotaxis
AzCIB_3161	COG2201	protein-glutamate methylesterase activity
AzCIB_3163	COG1360	Flagellar Motor Protein
AzCIB_3164	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AzCIB_3167	COG0745	RESPONSE REGULATOR receiver
AzCIB_3167	COG3706	GGDEF domain
AzCIB_3169	COG0402	S-adenosylhomocysteine deaminase activity
AzCIB_3170	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AzCIB_3172	COG0318	PFAM AMP-dependent synthetase and ligase
AzCIB_3174	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AzCIB_3175	COG1960	acyl-CoA dehydrogenase activity
AzCIB_3178	COG0583	DNA-binding transcription factor activity
AzCIB_3179	COG2423	ornithine cyclodeaminase activity
AzCIB_3181	COG1228	amidohydrolase
AzCIB_3182	COG0010	Belongs to the arginase family
AzCIB_3188	COG3012	SEC-C Motif Domain Protein
AzCIB_3189	COG4372	Transposase
AzCIB_3190	COG3436	PFAM IS66 Orf2 family protein
AzCIB_3193	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AzCIB_3195	COG1982	Orn Lys Arg decarboxylase major
AzCIB_3196	COG0717	Belongs to the dCTP deaminase family
AzCIB_3197	COG0489	protein tyrosine kinase activity
AzCIB_3199	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AzCIB_3199	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AzCIB_3200	COG0659	secondary active sulfate transmembrane transporter activity
AzCIB_3201	COG1254	Belongs to the acylphosphatase family
AzCIB_3206	COG0450	alkyl hydroperoxide reductase
AzCIB_3211	COG0280	phosphate acetyltransferase
AzCIB_3211	COG0281	malic enzyme
AzCIB_3212	COG1192	Involved in chromosome partitioning
AzCIB_3213	COG0210	DNA helicase
AzCIB_3215	COG0495	leucyl-tRNA aminoacylation
AzCIB_3217	COG1466	dna polymerase III delta subunit
AzCIB_3218	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AzCIB_3220	COG4974	Belongs to the 'phage' integrase family
AzCIB_3221	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AzCIB_3224	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AzCIB_3225	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AzCIB_3226	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AzCIB_3227	COG1610	YqeY-like protein
AzCIB_3229	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AzCIB_3241	COG3501	Rhs element vgr protein
AzCIB_3245	COG3012	SEC-C Motif Domain Protein
AzCIB_3246	COG4372	Transposase
AzCIB_3247	COG3436	PFAM IS66 Orf2 family protein
AzCIB_3255	COG2308	Evidence 4 Homologs of previously reported genes of
AzCIB_3262	COG0730	response to heat
AzCIB_3263	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AzCIB_3266	COG4206	TonB-dependent receptor
AzCIB_3270	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AzCIB_3272	COG0538	isocitrate dehydrogenase activity
AzCIB_3274	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AzCIB_3277	COG2863	cytochrome
AzCIB_3278	COG0446	pyridine nucleotide-disulphide oxidoreductase
AzCIB_3280	COG0756	dUTP diphosphatase activity
AzCIB_3281	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AzCIB_3282	COG2003	Belongs to the UPF0758 family
AzCIB_3283	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AzCIB_3284	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AzCIB_3285	COG1278	Cold shock
AzCIB_3286	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AzCIB_3287	COG0542	response to heat
AzCIB_3288	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AzCIB_3291	COG0745	RESPONSE REGULATOR receiver
AzCIB_3292	COG2205	protein histidine kinase activity
AzCIB_3293	COG0583	DNA-binding transcription factor activity
AzCIB_3296	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AzCIB_3297	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AzCIB_3301	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AzCIB_3303	COG0802	atpase or kinase
AzCIB_3304	COG0860	N-Acetylmuramoyl-L-alanine amidase
AzCIB_3305	COG0196	riboflavin kinase activity
AzCIB_3306	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AzCIB_3307	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AzCIB_3308	COG1047	Peptidyl-prolyl cis-trans
AzCIB_3309	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AzCIB_3313	COG1722	exodeoxyribonuclease VII activity
AzCIB_3314	COG0142	geranyltranstransferase activity
AzCIB_3315	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AzCIB_3316	COG1469	GTP cyclohydrolase I activity
AzCIB_3317	COG2030	dehydratase
AzCIB_3319	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AzCIB_3320	COG0142	geranyltranstransferase activity
AzCIB_3321	COG0584	glycerophosphoryl diester phosphodiesterase
AzCIB_3324	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
AzCIB_3325	COG0513	Belongs to the DEAD box helicase family
AzCIB_3328	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AzCIB_3329	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AzCIB_3330	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AzCIB_3332	COG0598	Magnesium transport protein CorA
AzCIB_3333	COG0631	protein serine/threonine phosphatase activity
AzCIB_3334	COG0247	lactate metabolic process
AzCIB_3335	COG0277	FAD linked oxidase domain protein
AzCIB_3337	COG0277	FAD linked oxidase domain protein
AzCIB_3338	COG2186	Transcriptional regulator
AzCIB_3339	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AzCIB_3340	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AzCIB_3341	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AzCIB_3342	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AzCIB_3352	COG1459	type II secretion system
AzCIB_3353	COG0741	lytic transglycosylase activity
AzCIB_3354	COG1819	glycosyl
AzCIB_3359	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AzCIB_3361	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AzCIB_3362	COG0745	RESPONSE REGULATOR receiver
AzCIB_3363	COG0604	alcohol dehydrogenase
AzCIB_3365	COG1704	LemA family
AzCIB_3373	COG2204	response regulator
AzCIB_3374	COG5002	protein histidine kinase activity
AzCIB_3375	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AzCIB_3390	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AzCIB_3391	COG1126	abc transporter atp-binding protein
AzCIB_3392	COG0765	amino acid transport
AzCIB_3393	COG0765	amino acid transport
AzCIB_3395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AzCIB_3399	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AzCIB_3401	COG2204	response regulator
AzCIB_3404	COG2319	Wd-40 repeat
AzCIB_3404	COG4249	Peptidase C14 caspase catalytic subunit p20
AzCIB_3408	COG1272	protein, Hemolysin III
AzCIB_3409	COG3409	Peptidoglycan-binding domain 1 protein
AzCIB_3409	COG3267	Type II secretory pathway component ExeA
AzCIB_3411	COG0583	DNA-binding transcription factor activity
AzCIB_3425	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AzCIB_3428	COG2201	protein-glutamate methylesterase activity
AzCIB_3432	COG2823	Periplasmic or secreted lipoprotein
AzCIB_3437	COG0469	pyruvate kinase activity
AzCIB_3438	COG2259	Doxx family
AzCIB_3439	COG3260	NADH ubiquinone oxidoreductase 20
AzCIB_3440	COG0649	NAD binding
AzCIB_3441	COG0651	ATP synthesis coupled electron transport
AzCIB_3443	COG0650	Formate hydrogenlyase subunit 4
AzCIB_3444	COG0651	ATP synthesis coupled electron transport
AzCIB_3447	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AzCIB_3447	COG0438	transferase activity, transferring glycosyl groups
AzCIB_3450	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AzCIB_3451	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AzCIB_3452	COG0697	spore germination
AzCIB_3453	COG0004	ammonium transporteR
AzCIB_3455	COG2353	YceI-like domain
AzCIB_3456	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AzCIB_3465	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AzCIB_3468	COG2022	thiamine diphosphate biosynthetic process
AzCIB_3470	COG2855	membrane
AzCIB_3473	COG1113	amino acid transport
AzCIB_3481	COG0730	response to heat
AzCIB_3483	COG1414	Transcriptional regulator
AzCIB_3484	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AzCIB_3486	COG2733	membrane
AzCIB_3488	COG0861	Integral membrane protein TerC family
AzCIB_3489	COG5002	protein histidine kinase activity
AzCIB_3493	COG0745	RESPONSE REGULATOR receiver
AzCIB_3494	COG0642	Histidine kinase
AzCIB_3495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AzCIB_3501	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AzCIB_3505	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AzCIB_3507	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AzCIB_3508	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AzCIB_3509	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AzCIB_3510	COG0628	permease
AzCIB_3512	COG0560	Phosphoserine phosphatase
AzCIB_3513	COG0617	tRNA 3'-terminal CCA addition
AzCIB_3516	COG1428	Deoxynucleoside kinase
AzCIB_3517	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AzCIB_3518	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AzCIB_3520	COG0308	aminopeptidase N
AzCIB_3525	COG0028	Belongs to the TPP enzyme family
AzCIB_3527	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AzCIB_3528	COG0688	phosphatidylethanolamine metabolic process
AzCIB_3529	COG1183	phosphatidylcholine synthase activity
AzCIB_3530	COG1368	sulfuric ester hydrolase activity
AzCIB_3534	COG2205	protein histidine kinase activity
AzCIB_3535	COG0745	RESPONSE REGULATOR receiver
AzCIB_3537	COG1858	cytochrome C peroxidase
AzCIB_3540	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AzCIB_3543	COG1295	ribonuclease BN
AzCIB_3545	COG0228	four-way junction DNA binding
AzCIB_3546	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AzCIB_3547	COG0336	Belongs to the RNA methyltransferase TrmD family
AzCIB_3548	COG0335	large ribosomal subunit rRNA binding
AzCIB_3550	COG0527	aspartate kinase activity
AzCIB_3553	COG0720	synthase
AzCIB_3554	COG3264	Mechanosensitive ion channel
AzCIB_3554	COG1196	nuclear chromosome segregation
AzCIB_3555	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AzCIB_3556	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AzCIB_3556	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AzCIB_3558	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AzCIB_3559	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AzCIB_3561	COG0187	DNA topoisomerase II activity
AzCIB_3564	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AzCIB_3564	COG4651	solute:proton antiporter activity
AzCIB_3565	COG1360	Flagellar Motor Protein
AzCIB_3566	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AzCIB_3567	COG1191	sigma factor activity
AzCIB_3570	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AzCIB_3571	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AzCIB_3574	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AzCIB_3577	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AzCIB_3578	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AzCIB_3579	COG0123	including yeast histone deacetylase and acetoin utilization protein
AzCIB_3580	COG0714	Associated with various cellular activities
AzCIB_3583	COG2951	lytic endotransglycosylase activity
AzCIB_3584	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AzCIB_3586	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AzCIB_3587	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AzCIB_3589	COG0776	regulation of translation
AzCIB_3590	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AzCIB_3590	COG0072	phenylalanine-tRNA ligase activity
AzCIB_3591	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AzCIB_3592	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AzCIB_3593	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AzCIB_3594	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AzCIB_3595	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AzCIB_3601	COG2010	Cytochrome c
AzCIB_3605	COG3391	amine dehydrogenase activity
AzCIB_3607	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AzCIB_3607	COG1648	precorrin-2 dehydrogenase activity
AzCIB_3613	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AzCIB_3615	COG0776	regulation of translation
AzCIB_3618	COG0287	Prephenate dehydrogenase
AzCIB_3620	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AzCIB_3622	COG0402	S-adenosylhomocysteine deaminase activity
AzCIB_3624	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AzCIB_3632	COG0346	lactoylglutathione lyase activity
AzCIB_3636	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AzCIB_3640	COG1459	type II secretion system
AzCIB_3644	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AzCIB_3648	COG0494	nUDIX hydrolase
AzCIB_3651	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AzCIB_3653	COG0175	sulfate reduction
AzCIB_3654	COG1218	3'(2'),5'-bisphosphate nucleotidase
AzCIB_3655	COG3273	potassium ion transport
AzCIB_3655	COG0471	metal ion transport
AzCIB_3656	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AzCIB_3657	COG0318	PFAM AMP-dependent synthetase and ligase
AzCIB_3660	COG5652	VanZ like family
AzCIB_3667	COG1215	transferase activity, transferring glycosyl groups
AzCIB_3669	COG0463	Glycosyl transferase, family 2
AzCIB_3671	COG1216	Glycosyl transferase, family 2
AzCIB_3674	COG0297	glycogen (starch) synthase activity
AzCIB_3677	COG1696	Membrane protein involved in D-alanine export
AzCIB_3679	COG0367	asparagine synthase
AzCIB_3680	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AzCIB_3686	COG0367	asparagine synthase
AzCIB_3687	COG0438	transferase activity, transferring glycosyl groups
AzCIB_3690	COG0726	polysaccharide deacetylase
AzCIB_3692	COG3409	Peptidoglycan-binding domain 1 protein
AzCIB_3692	COG3267	Type II secretory pathway component ExeA
AzCIB_3694	COG0489	protein tyrosine kinase activity
AzCIB_3698	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AzCIB_3701	COG1999	signal sequence binding
AzCIB_3702	COG0109	protoheme IX farnesyltransferase activity
AzCIB_3708	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AzCIB_3709	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AzCIB_3712	COG4221	oxidoreductase activity
AzCIB_3716	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AzCIB_3720	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AzCIB_3721	COG3852	Histidine kinase
AzCIB_3722	COG4251	negative regulation of phosphorylation
AzCIB_3722	COG2203	Gaf domain
AzCIB_3722	COG3706	GGDEF domain
AzCIB_3722	COG5001	Diguanylate cyclase
AzCIB_3724	COG0514	ATP-dependent DNA helicase (RecQ)
AzCIB_3725	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AzCIB_3727	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AzCIB_3731	COG0443	Heat shock 70 kDa protein
AzCIB_3735	COG0411	ABC transporter
AzCIB_3737	COG1522	sequence-specific DNA binding
AzCIB_3739	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AzCIB_3740	COG2911	Protein conserved in bacteria
AzCIB_3741	COG0134	indole-3-glycerol-phosphate synthase activity
AzCIB_3742	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AzCIB_3745	COG0546	phosphoglycolate phosphatase activity
AzCIB_3747	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AzCIB_3749	COG1716	ATPase activity
AzCIB_3750	COG0631	protein serine/threonine phosphatase activity
AzCIB_3756	COG4566	intracellular signal transduction
AzCIB_3757	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AzCIB_3758	COG0037	tRNA processing
AzCIB_3759	COG0825	malonyl-CoA metabolic process
AzCIB_3761	COG1253	flavin adenine dinucleotide binding
AzCIB_3762	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AzCIB_3763	COG0670	Belongs to the BI1 family
AzCIB_3765	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AzCIB_3766	COG0343	queuine tRNA-ribosyltransferase activity
AzCIB_3767	COG1862	Preprotein translocase
AzCIB_3768	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AzCIB_3769	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AzCIB_3770	COG2095	MarC family integral membrane protein
AzCIB_3773	COG2967	ApaG domain
AzCIB_3774	COG0784	Response regulator, receiver
AzCIB_3774	COG4191	Histidine kinase
AzCIB_3775	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AzCIB_3777	COG0653	protein targeting
AzCIB_3780	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AzCIB_3781	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AzCIB_3784	COG1181	Belongs to the D-alanine--D-alanine ligase family
AzCIB_3785	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AzCIB_3786	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AzCIB_3787	COG0772	Belongs to the SEDS family
AzCIB_3788	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AzCIB_3789	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AzCIB_3790	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AzCIB_3791	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AzCIB_3794	COG0275	rRNA processing
AzCIB_3795	COG2001	Belongs to the MraZ family
AzCIB_3799	COG0418	dihydroorotase activity
AzCIB_3801	COG0792	nuclease activity
AzCIB_3802	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AzCIB_3803	COG2823	Periplasmic or secreted lipoprotein
AzCIB_3804	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AzCIB_3806	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AzCIB_3807	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AzCIB_3808	COG0511	ligase activity, forming carbon-carbon bonds
AzCIB_3809	COG0439	Biotin carboxylase
AzCIB_3810	COG2264	protein methyltransferase activity
AzCIB_3815	COG0537	adenosine 5'-monophosphoramidase activity
AzCIB_3820	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AzCIB_3822	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AzCIB_3827	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AzCIB_3833	COG0463	Glycosyl transferase, family 2
AzCIB_3841	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AzCIB_3841	COG0662	Cupin 2, conserved barrel domain protein
AzCIB_3848	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AzCIB_3851	COG1309	transcriptional regulator
AzCIB_3853	COG2119	membrane
AzCIB_3854	COG2022	thiamine diphosphate biosynthetic process
AzCIB_3856	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AzCIB_3858	COG0022	dehydrogenase e1 component
AzCIB_3859	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AzCIB_3860	COG3284	Transcriptional regulator
AzCIB_3861	COG1393	Belongs to the ArsC family
AzCIB_3865	COG0351	phosphomethylpyrimidine kinase
AzCIB_3867	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AzCIB_3868	COG3258	Cytochrome c
AzCIB_3871	COG1968	undecaprenyl-diphosphatase activity
AzCIB_3872	COG3150	esterase
AzCIB_3873	COG2226	methyltransferase
AzCIB_3874	COG2962	Rard protein
AzCIB_3875	COG0557	exoribonuclease II activity
AzCIB_3877	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AzCIB_3878	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AzCIB_3879	COG2239	Acts as a magnesium transporter
AzCIB_3880	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AzCIB_3881	COG0352	thiamine-phosphate diphosphorylase activity
AzCIB_3882	COG0351	phosphomethylpyrimidine kinase
AzCIB_3887	COG0643	Histidine kinase
AzCIB_3887	COG2198	Histidine kinase
AzCIB_3888	COG0415	Belongs to the DNA photolyase family
AzCIB_3889	COG1678	Uncharacterized ACR, COG1678
AzCIB_3890	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AzCIB_3891	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AzCIB_3892	COG0540	Belongs to the ATCase OTCase family
AzCIB_3894	COG1872	DUF167
AzCIB_3895	COG0762	integral membrane protein
AzCIB_3904	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AzCIB_3907	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AzCIB_3907	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AzCIB_3910	COG2200	EAL domain
AzCIB_3910	COG2199	diguanylate cyclase activity
AzCIB_3912	COG2197	response regulator
AzCIB_3913	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AzCIB_3914	COG2274	protein secretion by the type I secretion system
AzCIB_3916	COG0735	belongs to the Fur family
AzCIB_3917	COG1121	(ABC) transporter
AzCIB_3920	COG1280	lysine exporter protein (LysE YggA)
AzCIB_3921	COG0730	response to heat
AzCIB_3922	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AzCIB_3924	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AzCIB_3925	COG0129	dihydroxy-acid dehydratase activity
AzCIB_3926	COG3132	Protein of unknown function, DUF480
AzCIB_3927	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AzCIB_3929	COG5001	Diguanylate cyclase
AzCIB_3939	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AzCIB_3940	COG1136	(ABC) transporter
AzCIB_3940	COG0577	efflux transmembrane transporter activity
AzCIB_3941	COG1538	Outer membrane efflux protein
AzCIB_3946	COG0672	)-iron permease
AzCIB_3951	COG4774	siderophore transport
AzCIB_3955	COG3781	membrane
AzCIB_3961	COG5002	protein histidine kinase activity
AzCIB_3965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AzCIB_3966	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AzCIB_3971	COG4969	Belongs to the N-Me-Phe pilin family
AzCIB_3978	COG0436	Aminotransferase
AzCIB_3979	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AzCIB_3980	COG0235	Class ii aldolase
AzCIB_3981	COG2084	Dehydrogenase
AzCIB_3982	COG2084	Dehydrogenase
AzCIB_3983	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AzCIB_3985	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AzCIB_3986	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AzCIB_3992	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AzCIB_3994	COG2333	competence protein COMEC
AzCIB_3994	COG0658	competence protein
AzCIB_3995	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AzCIB_3999	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AzCIB_4002	COG1033	growth of symbiont in host cell
AzCIB_4002	COG2409	Drug exporters of the RND superfamily
AzCIB_4003	COG4447	cellulose binding
AzCIB_4004	COG4647	ligase activity
AzCIB_4005	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
AzCIB_4006	COG0145	ligase activity
AzCIB_4008	COG2814	Major facilitator Superfamily
AzCIB_4011	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AzCIB_4012	COG0203	ribosomal protein L17
AzCIB_4013	COG0202	RNA polymerase activity
AzCIB_4014	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AzCIB_4015	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AzCIB_4016	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AzCIB_4017	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AzCIB_4018	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AzCIB_4019	COG0201	protein transport
AzCIB_4020	COG0200	Binds to the 23S rRNA
AzCIB_4021	COG1841	ribosomal large subunit assembly
AzCIB_4022	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AzCIB_4023	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AzCIB_4024	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AzCIB_4025	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AzCIB_4026	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AzCIB_4027	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AzCIB_4028	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AzCIB_4029	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AzCIB_4030	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AzCIB_4031	COG0255	Belongs to the universal ribosomal protein uL29 family
AzCIB_4032	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AzCIB_4033	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AzCIB_4034	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AzCIB_4035	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AzCIB_4036	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AzCIB_4037	COG0089	rRNA binding
AzCIB_4038	COG0088	Forms part of the polypeptide exit tunnel
AzCIB_4039	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AzCIB_4040	COG0051	transcription antitermination factor activity, RNA binding
AzCIB_4041	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AzCIB_4042	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AzCIB_4043	COG0049	tRNA binding
AzCIB_4044	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AzCIB_4045	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AzCIB_4046	COG0085	RNA polymerase activity
AzCIB_4047	COG0222	ribosome binding
AzCIB_4048	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AzCIB_4049	COG0081	regulation of translation
AzCIB_4050	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AzCIB_4052	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AzCIB_4053	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AzCIB_4054	COG0277	FAD linked oxidase domain protein
AzCIB_4058	COG2197	response regulator
AzCIB_4060	COG3437	response regulator, receiver
AzCIB_4060	COG3850	Histidine kinase
AzCIB_4060	COG2205	protein histidine kinase activity
AzCIB_4060	COG4999	Histidine kinase
AzCIB_4063	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AzCIB_4070	COG1022	Amp-dependent synthetase and ligase
AzCIB_4077	COG0586	Pfam SNARE associated Golgi protein
AzCIB_4078	COG1716	ATPase activity
AzCIB_4078	COG5001	Diguanylate cyclase
AzCIB_4079	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AzCIB_4080	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AzCIB_4080	COG1703	isobutyryl-CoA mutase activity
AzCIB_4080	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AzCIB_4085	COG2321	neutral zinc metallopeptidase
AzCIB_4089	COG0439	Biotin carboxylase
AzCIB_4090	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AzCIB_4091	COG1703	isobutyryl-CoA mutase activity
AzCIB_4092	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AzCIB_4092	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AzCIB_4093	COG1802	Transcriptional regulator
AzCIB_4094	COG0114	fumarate hydratase activity
AzCIB_4102	COG2201	protein-glutamate methylesterase activity
AzCIB_4108	COG4964	Belongs to the GSP D family
AzCIB_4120	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AzCIB_4121	COG3162	membrane
AzCIB_4122	COG1024	Enoyl-CoA hydratase
AzCIB_4123	COG1492	cobalamin metabolic process
AzCIB_4126	COG1242	4 iron, 4 sulfur cluster binding
AzCIB_4127	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AzCIB_4129	COG0513	Belongs to the DEAD box helicase family
AzCIB_4134	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
AzCIB_4142	COG0427	acetyl-CoA hydrolase
AzCIB_4143	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AzCIB_4146	COG0583	DNA-binding transcription factor activity
AzCIB_4147	COG1028	Short-chain dehydrogenase reductase Sdr
AzCIB_4148	COG0393	Putative heavy-metal-binding
AzCIB_4149	COG1280	lysine exporter protein (LysE YggA)
AzCIB_4151	COG0545	Peptidyl-prolyl cis-trans isomerase
AzCIB_4152	COG1199	ATP-dependent helicase activity
AzCIB_4152	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AzCIB_4154	COG2132	Multicopper oxidase
AzCIB_4155	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AzCIB_4156	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AzCIB_4158	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AzCIB_4160	COG0070	glutamate synthase
AzCIB_4160	COG0069	glutamate synthase activity
AzCIB_4160	COG0067	glutamate synthase
AzCIB_4161	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AzCIB_4162	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AzCIB_4163	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AzCIB_4170	COG1965	Belongs to the frataxin family
AzCIB_4179	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AzCIB_4180	COG0284	orotidine-5'-phosphate decarboxylase activity
AzCIB_4182	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AzCIB_4183	COG3161	chorismate lyase activity
AzCIB_4184	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AzCIB_4187	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
AzCIB_4195	COG1858	cytochrome C peroxidase
AzCIB_4197	COG1741	Belongs to the pirin family
AzCIB_4198	COG0778	Nitroreductase
AzCIB_4200	COG0183	Belongs to the thiolase family
AzCIB_4201	COG1024	Enoyl-CoA hydratase
AzCIB_4201	COG1250	3-hydroxyacyl-CoA dehydrogenase
AzCIB_4204	COG1250	3-hydroxyacyl-CoA dehydrogenase
AzCIB_4204	COG1024	Enoyl-CoA hydratase
AzCIB_4206	COG1960	acyl-CoA dehydrogenase activity
AzCIB_4207	COG1309	transcriptional regulator
AzCIB_4209	COG0583	DNA-binding transcription factor activity
AzCIB_4210	COG0288	reversible hydration of carbon dioxide
AzCIB_4212	COG4178	(ABC) transporter
AzCIB_4214	COG0366	Alpha amylase catalytic
AzCIB_4215	COG1322	Protein conserved in bacteria
AzCIB_4216	COG5265	(ABC) transporter
AzCIB_4219	COG0583	DNA-binding transcription factor activity
AzCIB_4220	COG0730	response to heat
AzCIB_4223	COG0175	sulfate reduction
AzCIB_4225	COG0175	sulfate reduction
AzCIB_4226	COG2895	sulfate adenylyltransferase (ATP) activity
AzCIB_4229	COG0330	HflC and HflK could
AzCIB_4230	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AzCIB_4233	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AzCIB_4234	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AzCIB_4236	COG0824	Thioesterase
AzCIB_4237	COG0811	peptide transport
AzCIB_4240	COG0823	Involved in the tonB-independent uptake of proteins
AzCIB_4243	COG0602	queuosine metabolic process
AzCIB_4244	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AzCIB_4245	COG5002	protein histidine kinase activity
AzCIB_4246	COG2204	response regulator
AzCIB_4247	COG3300	MHYT domain
AzCIB_4247	COG5001	Diguanylate cyclase
AzCIB_4248	COG0318	PFAM AMP-dependent synthetase and ligase
AzCIB_4253	COG4214	carbohydrate transport
AzCIB_4256	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AzCIB_4257	COG1546	Belongs to the CinA family
AzCIB_4258	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AzCIB_4259	COG2137	regulation of response to DNA damage stimulus
AzCIB_4260	COG1137	ATPase activity
AzCIB_4261	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AzCIB_4262	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AzCIB_4264	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AzCIB_4265	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AzCIB_4266	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AzCIB_4267	COG0741	lytic transglycosylase activity
AzCIB_4270	COG0617	tRNA 3'-terminal CCA addition
AzCIB_4275	COG1028	Short-chain dehydrogenase reductase Sdr
AzCIB_4276	COG0037	tRNA processing
AzCIB_4278	COG1238	metal cluster binding
AzCIB_4279	COG0251	oxidation-reduction process
AzCIB_4281	COG1132	(ABC) transporter
AzCIB_4283	COG0243	molybdopterin cofactor binding
AzCIB_4285	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AzCIB_4286	COG0708	Exodeoxyribonuclease III
AzCIB_4287	COG1917	Cupin 2, conserved barrel domain protein
AzCIB_4287	COG2207	Transcriptional regulator
AzCIB_4293	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AzCIB_4305	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AzCIB_4309	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AzCIB_4311	COG0861	Integral membrane protein TerC family
AzCIB_4312	COG4206	TonB-dependent receptor
AzCIB_4314	COG3876	Protein conserved in bacteria
AzCIB_4316	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AzCIB_4329	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AzCIB_4335	COG0411	ABC transporter
AzCIB_4337	COG2453	phosphatase
AzCIB_4337	COG0671	phosphoesterase, PA-phosphatase related
AzCIB_4342	COG1988	membrane-bound metal-dependent
AzCIB_4344	COG1028	Short-chain dehydrogenase reductase Sdr
AzCIB_4345	COG3848	Pyruvate phosphate dikinase
AzCIB_4345	COG0574	Belongs to the PEP-utilizing enzyme family
AzCIB_4351	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AzCIB_4352	COG2814	Major facilitator Superfamily
AzCIB_4353	COG0606	chelatase, subunit chli
AzCIB_4356	COG0347	Belongs to the P(II) protein family
AzCIB_4357	COG0004	ammonium transporteR
AzCIB_4358	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AzCIB_4362	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AzCIB_4364	COG0488	(ABC) transporter
AzCIB_4367	COG0697	spore germination
AzCIB_4369	COG0189	ligase activity
AzCIB_4375	COG1404	Belongs to the peptidase S8 family
AzCIB_4377	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AzCIB_4380	COG3436	PFAM IS66 Orf2 family protein
AzCIB_4381	COG4372	Transposase
AzCIB_4382	COG3012	SEC-C Motif Domain Protein
AzCIB_4385	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AzCIB_4386	COG1561	YicC-like family, N-terminal region
AzCIB_4387	COG0515	serine threonine protein kinase
AzCIB_4387	COG2815	serine threonine protein kinase
AzCIB_4389	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AzCIB_4390	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AzCIB_4391	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AzCIB_4392	COG0616	signal peptide processing
AzCIB_4393	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AzCIB_4394	COG2022	thiamine diphosphate biosynthetic process
AzCIB_4396	COG0582	viral genome integration into host DNA
AzCIB_4399	COG0583	DNA-binding transcription factor activity
AzCIB_4403	COG3436	PFAM IS66 Orf2 family protein
AzCIB_4404	COG4372	Transposase
AzCIB_4405	COG3012	SEC-C Motif Domain Protein
AzCIB_4406	COG2267	carboxylic ester hydrolase activity
AzCIB_4409	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AzCIB_4410	COG4569	acetaldehyde dehydrogenase (acetylating) activity
AzCIB_4412	COG0346	lactoylglutathione lyase activity
AzCIB_4414	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AzCIB_4415	COG2146	nitrite reductase [NAD(P)H] activity
AzCIB_4419	COG1802	Transcriptional regulator
AzCIB_4426	COG1733	regulation of RNA biosynthetic process
AzCIB_4431	COG1902	pentaerythritol trinitrate reductase activity
AzCIB_4432	COG0842	Transport permease protein
AzCIB_4433	COG0842	Transport permease protein
AzCIB_4433	COG1129	ABC transporter
AzCIB_4434	COG1129	ABC transporter
AzCIB_4434	COG0842	Transport permease protein
AzCIB_4435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AzCIB_4438	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AzCIB_4439	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AzCIB_4441	COG1752	Esterase of the alpha-beta hydrolase superfamily
AzCIB_4446	COG5433	transposase activity
AzCIB_4456	COG2003	Belongs to the UPF0758 family
AzCIB_4471	COG2814	Major facilitator Superfamily
AzCIB_4474	COG1024	Enoyl-CoA hydratase
AzCIB_4476	COG1960	acyl-CoA dehydrogenase activity
AzCIB_4477	COG0427	acetyl-CoA hydrolase
AzCIB_4478	COG1960	acyl-CoA dehydrogenase activity
AzCIB_4479	COG1013	pyruvate-flavodoxin oxidoreductase activity
AzCIB_4480	COG0674	pyruvate-flavodoxin oxidoreductase activity
AzCIB_4480	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AzCIB_4481	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AzCIB_4486	COG1250	3-hydroxyacyl-CoA dehydrogenase
AzCIB_4487	COG1024	Enoyl-CoA hydratase
AzCIB_4488	COG0183	Belongs to the thiolase family
AzCIB_4495	COG0559	Belongs to the binding-protein-dependent transport system permease family
AzCIB_4497	COG0411	ABC transporter
AzCIB_4500	COG1309	transcriptional regulator
AzCIB_4517	COG1881	PFAM PEBP family protein
AzCIB_4518	COG1024	Enoyl-CoA hydratase
AzCIB_4523	COG1028	Short-chain dehydrogenase reductase Sdr
AzCIB_4524	COG1028	Short-chain dehydrogenase reductase Sdr
AzCIB_4525	COG3321	synthase
AzCIB_4525	COG1028	Short-chain dehydrogenase reductase Sdr
AzCIB_4525	COG0604	alcohol dehydrogenase
AzCIB_4542	COG0776	regulation of translation
AzCIB_4548	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AzCIB_4562	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AzCIB_4571	COG1192	Involved in chromosome partitioning
AzCIB_4574	COG2032	superoxide dismutase activity
AzCIB_4575	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AzCIB_4582	COG0559	Belongs to the binding-protein-dependent transport system permease family
AzCIB_4583	COG2860	membrane
AzCIB_4584	COG1970	mechanosensitive ion channel activity
AzCIB_4585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AzCIB_4586	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AzCIB_4593	COG3383	formate dehydrogenase (NAD+) activity
AzCIB_4595	COG0583	DNA-binding transcription factor activity
AzCIB_4598	COG0840	transmembrane signaling receptor activity
AzCIB_4599	COG3040	lipid binding
AzCIB_4601	COG1136	(ABC) transporter
AzCIB_4604	COG1943	Transposase
AzCIB_4606	COG3039	Transposase
AzCIB_4608	COG1309	transcriptional regulator
AzCIB_4609	COG1024	Enoyl-CoA hydratase
AzCIB_4610	COG1024	Enoyl-CoA hydratase
AzCIB_4616	COG1960	acyl-CoA dehydrogenase activity
AzCIB_4623	COG1773	rubredoxin
AzCIB_4628	COG0411	ABC transporter
AzCIB_4647	COG0488	(ABC) transporter
AzCIB_4649	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AzCIB_4650	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AzCIB_4651	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AzCIB_4652	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AzCIB_4655	COG2814	Major facilitator Superfamily
AzCIB_4680	COG2885	chlorophyll binding
AzCIB_4684	COG3093	addiction module antidote protein HigA
AzCIB_4692	COG1028	Short-chain dehydrogenase reductase Sdr
AzCIB_4693	COG0596	Alpha beta hydrolase
AzCIB_4695	COG2258	MOSC domain
AzCIB_4696	COG3501	Rhs element vgr protein
AzCIB_4702	COG1024	Enoyl-CoA hydratase
AzCIB_4702	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AzCIB_4703	COG0309	Hydrogenase expression formation protein (HypE)
AzCIB_4704	COG0409	Hydrogenase expression formation protein
AzCIB_4705	COG0298	carbon dioxide binding
AzCIB_4706	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AzCIB_4708	COG0375	protein maturation
AzCIB_4710	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AzCIB_4711	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AzCIB_4716	COG3181	Tripartite tricarboxylate transporter family receptor
AzCIB_4717	COG0642	Histidine kinase
AzCIB_4719	COG1840	ABC-type Fe3 transport system, periplasmic component
AzCIB_4722	COG1295	ribonuclease BN
AzCIB_4723	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AzCIB_4724	COG0569	domain protein
AzCIB_4725	COG2204	response regulator
AzCIB_4726	COG5000	phosphorelay sensor kinase activity
AzCIB_4728	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AzCIB_4729	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AzCIB_4735	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AzCIB_4736	COG0706	membrane insertase activity
AzCIB_4737	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AzCIB_4738	COG0594	ribonuclease P activity
AzCIB_4739	COG0230	Belongs to the bacterial ribosomal protein bL34 family