locus-tag	class	description
AZC_0001	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AZC_0002	COG0424	maF-like protein
AZC_0003	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AZC_0004	COG0237	dephospho-CoA kinase activity
AZC_0005	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AZC_0008	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AZC_0009	COG1702	phosphate starvation-inducible protein PhoH
AZC_0010	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AZC_0011	COG1253	flavin adenine dinucleotide binding
AZC_0012	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AZC_0013	COG1396	sequence-specific DNA binding
AZC_0014	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AZC_0015	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AZC_0017	COG0779	Required for maturation of 30S ribosomal subunits
AZC_0020	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AZC_0021	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AZC_0022	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AZC_0024	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_0027	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AZC_0032	COG1522	sequence-specific DNA binding
AZC_0033	COG2030	dehydratase
AZC_0034	COG0625	glutathione transferase activity
AZC_0037	COG0156	8-amino-7-oxononanoate synthase activity
AZC_0038	COG0300	oxidoreductase activity
AZC_0058	COG2096	Adenosyltransferase
AZC_0061	COG0840	transmembrane signaling receptor activity
AZC_0063	COG1185	polyribonucleotide nucleotidyltransferase activity
AZC_0064	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AZC_0066	COG2072	flavoprotein involved in K transport
AZC_0068	COG0438	transferase activity, transferring glycosyl groups
AZC_0069	COG2144	transferase activity, transferring acyl groups
AZC_0074	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZC_0078	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AZC_0079	COG0352	thiamine-phosphate diphosphorylase activity
AZC_0080	COG0247	lactate metabolic process
AZC_0081	COG2852	Protein conserved in bacteria
AZC_0082	COG0277	FAD linked oxidase domain protein
AZC_0083	COG0277	FAD linked oxidase domain protein
AZC_0084	COG0583	DNA-binding transcription factor activity
AZC_0091	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AZC_0091	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AZC_0095	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AZC_0096	COG1674	ftsk spoiiie
AZC_0097	COG0436	Aminotransferase
AZC_0098	COG0196	riboflavin kinase activity
AZC_0101	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AZC_0102	COG2183	response to ionizing radiation
AZC_0103	COG1794	racemase activity, acting on amino acids and derivatives
AZC_0104	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AZC_0105	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AZC_0107	COG2271	Major facilitator Superfamily
AZC_0108	COG0242	peptide deformylase activity
AZC_0109	COG1201	RNA secondary structure unwinding
AZC_0114	COG1902	pentaerythritol trinitrate reductase activity
AZC_0118	COG4566	intracellular signal transduction
AZC_0119	COG0281	malic enzyme
AZC_0120	COG2985	domain, Protein
AZC_0122	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AZC_0125	COG4191	Histidine kinase
AZC_0127	COG0583	DNA-binding transcription factor activity
AZC_0129	COG4172	Belongs to the ABC transporter superfamily
AZC_0132	COG4239	(ABC) transporter, permease
AZC_0133	COG4174	ABC transporter (Permease)
AZC_0134	COG4166	transmembrane transport
AZC_0135	COG4166	transmembrane transport
AZC_0136	COG3474	cytochrome
AZC_0137	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AZC_0138	COG0077	Prephenate dehydratase
AZC_0138	COG1605	Chorismate mutase
AZC_0140	COG2816	NAD+ diphosphatase activity
AZC_0142	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AZC_0144	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AZC_0147	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AZC_0149	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AZC_0156	COG0588	phosphoglycerate mutase activity
AZC_0157	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AZC_0159	COG0284	orotidine-5'-phosphate decarboxylase activity
AZC_0161	COG3963	phosphatidate phosphatase activity
AZC_0162	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AZC_0164	COG2951	lytic endotransglycosylase activity
AZC_0166	COG0745	RESPONSE REGULATOR receiver
AZC_0174	COG3395	kinase activity
AZC_0175	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AZC_0176	COG1454	alcohol dehydrogenase
AZC_0177	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AZC_0178	COG2271	Major facilitator Superfamily
AZC_0179	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AZC_0182	COG4774	siderophore transport
AZC_0183	COG1120	ATPase activity
AZC_0184	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AZC_0185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AZC_0190	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AZC_0191	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AZC_0193	COG4191	Histidine kinase
AZC_0194	COG4566	intracellular signal transduction
AZC_0195	COG2072	flavoprotein involved in K transport
AZC_0200	COG0410	ABC transporter
AZC_0204	COG0583	DNA-binding transcription factor activity
AZC_0205	COG1733	regulation of RNA biosynthetic process
AZC_0206	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_0207	COG1733	regulation of RNA biosynthetic process
AZC_0209	COG1335	isochorismatase
AZC_0214	COG2171	N-acyltransferase activity
AZC_0218	COG0006	proline dipeptidase activity
AZC_0221	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AZC_0222	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AZC_0224	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZC_0225	COG2226	methyltransferase
AZC_0227	COG0251	oxidation-reduction process
AZC_0228	COG2813	Specifically methylates the guanine in position
AZC_0228	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AZC_0229	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AZC_0234	COG1648	precorrin-2 dehydrogenase activity
AZC_0234	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AZC_0238	COG4957	zinc ion binding
AZC_0239	COG0842	Transport permease protein
AZC_0240	COG1131	(ABC) transporter
AZC_0241	COG1522	sequence-specific DNA binding
AZC_0243	COG0400	carboxylic ester hydrolase activity
AZC_0244	COG0346	lactoylglutathione lyase activity
AZC_0246	COG0583	DNA-binding transcription factor activity
AZC_0247	COG0625	glutathione transferase activity
AZC_0251	COG1573	uracil-dna glycosylase
AZC_0254	COG0840	transmembrane signaling receptor activity
AZC_0255	COG0471	metal ion transport
AZC_0257	COG0481	GTPase activity
AZC_0262	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AZC_0263	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AZC_0264	COG2329	Antibiotic biosynthesis monooxygenase
AZC_0266	COG1522	sequence-specific DNA binding
AZC_0267	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AZC_0278	COG5001	Diguanylate cyclase
AZC_0278	COG4251	negative regulation of phosphorylation
AZC_0278	COG3706	GGDEF domain
AZC_0278	COG2203	Gaf domain
AZC_0279	COG0791	NLP P60 protein
AZC_0280	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AZC_0283	COG0583	DNA-binding transcription factor activity
AZC_0284	COG2814	Major facilitator Superfamily
AZC_0286	COG1643	Atp-dependent helicase
AZC_0288	COG4689	acetoacetate decarboxylase
AZC_0292	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZC_0293	COG0697	spore germination
AZC_0301	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AZC_0302	COG4150	thiosulfate binding
AZC_0303	COG3411	Ferredoxin
AZC_0304	COG0473	3-isopropylmalate dehydrogenase activity
AZC_0307	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
AZC_0310	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AZC_0311	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AZC_0312	COG1309	transcriptional regulator
AZC_0314	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AZC_0317	COG0824	Thioesterase
AZC_0321	COG1012	belongs to the aldehyde dehydrogenase family
AZC_0333	COG0019	diaminopimelate decarboxylase activity
AZC_0334	COG0156	8-amino-7-oxononanoate synthase activity
AZC_0337	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AZC_0338	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AZC_0341	COG2814	Major facilitator Superfamily
AZC_0343	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AZC_0344	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AZC_0349	COG0069	glutamate synthase activity
AZC_0351	COG3706	GGDEF domain
AZC_0351	COG0745	RESPONSE REGULATOR receiver
AZC_0352	COG5002	protein histidine kinase activity
AZC_0359	COG0784	Response regulator, receiver
AZC_0361	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AZC_0366	COG3290	protein histidine kinase activity
AZC_0366	COG0840	transmembrane signaling receptor activity
AZC_0368	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AZC_0370	COG0400	carboxylic ester hydrolase activity
AZC_0372	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AZC_0376	COG1999	signal sequence binding
AZC_0378	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZC_0380	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
AZC_0383	COG0450	alkyl hydroperoxide reductase
AZC_0386	COG0534	Mate efflux family protein
AZC_0390	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AZC_0393	COG1793	dna ligase
AZC_0393	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AZC_0397	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AZC_0401	COG0354	folic acid binding
AZC_0402	COG2818	Glycosylase
AZC_0406	COG0456	acetyltransferase
AZC_0407	COG0009	L-threonylcarbamoyladenylate synthase
AZC_0410	COG0574	Belongs to the PEP-utilizing enzyme family
AZC_0410	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AZC_0411	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AZC_0411	COG2885	chlorophyll binding
AZC_0413	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZC_0414	COG0123	including yeast histone deacetylase and acetoin utilization protein
AZC_0421	COG1733	regulation of RNA biosynthetic process
AZC_0422	COG2910	NAD(P)H-binding
AZC_0424	COG0459	protein refolding
AZC_0425	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AZC_0430	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AZC_0431	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AZC_0432	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AZC_0439	COG2989	Protein conserved in bacteria
AZC_0440	COG3108	Peptidase M15
AZC_0441	COG3750	Belongs to the UPF0335 family
AZC_0446	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AZC_0447	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AZC_0451	COG0583	DNA-binding transcription factor activity
AZC_0453	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AZC_0456	COG1194	a g-specific adenine glycosylase
AZC_0460	COG0069	glutamate synthase activity
AZC_0460	COG0070	glutamate synthase
AZC_0460	COG0067	glutamate synthase
AZC_0462	COG1238	metal cluster binding
AZC_0464	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AZC_0465	COG1414	Transcriptional regulator
AZC_0467	COG1802	Transcriptional regulator
AZC_0469	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AZC_0472	COG0179	Fumarylacetoacetate (FAA) hydrolase
AZC_0477	COG0683	leucine binding
AZC_0481	COG0559	Belongs to the binding-protein-dependent transport system permease family
AZC_0482	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AZC_0483	COG1877	trehalose-phosphatase activity
AZC_0486	COG0678	peroxiredoxin activity
AZC_0488	COG1678	Uncharacterized ACR, COG1678
AZC_0493	COG0254	rRNA binding
AZC_0494	COG1132	(ABC) transporter
AZC_0498	COG0483	inositol monophosphate 1-phosphatase activity
AZC_0500	COG0352	thiamine-phosphate diphosphorylase activity
AZC_0501	COG3588	fructose-bisphosphate aldolase
AZC_0502	COG0126	phosphoglycerate kinase activity
AZC_0508	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AZC_0509	COG1692	metallophosphoesterase
AZC_0510	COG0217	transcriptional regulatory protein
AZC_0511	COG0789	Transcriptional regulator
AZC_0513	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AZC_0515	COG0632	four-way junction helicase activity
AZC_0519	COG2255	four-way junction helicase activity
AZC_0520	COG0824	Thioesterase
AZC_0524	COG0823	Involved in the tonB-independent uptake of proteins
AZC_0525	COG2885	chlorophyll binding
AZC_0527	COG0037	tRNA processing
AZC_0528	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AZC_0529	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AZC_0530	COG0305	Participates in initiation and elongation during chromosome replication
AZC_0532	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AZC_0534	COG1286	toxin biosynthetic process
AZC_0535	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AZC_0536	COG4221	oxidoreductase activity
AZC_0537	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AZC_0538	COG2161	toxin-antitoxin pair type II binding
AZC_0539	COG4115	mRNA cleavage
AZC_0540	COG2927	DNA polymerase III (CHI subunit)
AZC_0547	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AZC_0548	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AZC_0549	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AZC_0551	COG3264	Mechanosensitive ion channel
AZC_0551	COG1196	nuclear chromosome segregation
AZC_0552	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AZC_0554	COG0604	alcohol dehydrogenase
AZC_0557	COG0693	protein deglycase activity
AZC_0560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AZC_0561	COG0800	Aldolase
AZC_0563	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AZC_0564	COG0803	Belongs to the bacterial solute-binding protein 9 family
AZC_0565	COG0523	cobalamin synthesis protein
AZC_0567	COG0495	leucyl-tRNA aminoacylation
AZC_0571	COG2223	nitrite transmembrane transporter activity
AZC_0576	COG1960	acyl-CoA dehydrogenase activity
AZC_0578	COG0667	Aldo Keto reductase
AZC_0579	COG0318	PFAM AMP-dependent synthetase and ligase
AZC_0582	COG4988	ABC transporter
AZC_0583	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AZC_0585	COG1294	oxidase, subunit
AZC_0587	COG2824	Alkylphosphonate utilization operon protein PhnA
AZC_0591	COG3246	L-lysine catabolic process to acetate
AZC_0592	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AZC_0594	COG4191	Histidine kinase
AZC_0600	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
AZC_0607	COG0375	protein maturation
AZC_0609	COG2204	response regulator
AZC_0615	COG4191	Histidine kinase
AZC_0617	COG2199	diguanylate cyclase activity
AZC_0617	COG2203	Gaf domain
AZC_0617	COG2200	EAL domain
AZC_0618	COG0745	RESPONSE REGULATOR receiver
AZC_0620	COG0745	RESPONSE REGULATOR receiver
AZC_0621	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AZC_0625	COG1360	Flagellar Motor Protein
AZC_0628	COG1338	Plays a role in the flagellum-specific transport system
AZC_0630	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AZC_0632	COG1706	bacterial-type flagellum-dependent cell motility
AZC_0633	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
AZC_0634	COG4786	Flagellar basal body rod
AZC_0635	COG1677	Flagellar hook-basal body complex protein FliE
AZC_0636	COG1558	bacterial-type flagellum-dependent cell motility
AZC_0637	COG1815	bacterial-type flagellum-dependent cell motility
AZC_0639	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AZC_0640	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AZC_0641	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AZC_0644	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AZC_0645	COG4786	Flagellar basal body rod
AZC_0646	COG1157	protein secretion by the type III secretion system
AZC_0651	COG5443	negative regulation of bacterial-type flagellum assembly
AZC_0652	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AZC_0653	COG1987	bacterial-type flagellum assembly
AZC_0654	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AZC_0660	COG0840	transmembrane signaling receptor activity
AZC_0660	COG5278	phosphoserine phosphatase activity
AZC_0661	COG0643	Histidine kinase
AZC_0661	COG2198	Histidine kinase
AZC_0662	COG0835	chemotaxis
AZC_0664	COG2201	protein-glutamate methylesterase activity
AZC_0665	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AZC_0666	COG0840	transmembrane signaling receptor activity
AZC_0670	COG3729	General stress protein
AZC_0671	COG2855	membrane
AZC_0672	COG0583	DNA-binding transcription factor activity
AZC_0674	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AZC_0677	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AZC_0679	COG0243	molybdopterin cofactor binding
AZC_0680	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AZC_0681	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AZC_0682	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AZC_0684	COG1116	anion transmembrane transporter activity
AZC_0685	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_0686	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZC_0689	COG0484	heat shock protein binding
AZC_0690	COG0443	Heat shock 70 kDa protein
AZC_0691	COG1116	anion transmembrane transporter activity
AZC_0691	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZC_0692	COG2201	protein-glutamate methylesterase activity
AZC_0698	COG2267	carboxylic ester hydrolase activity
AZC_0701	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AZC_0703	COG3454	Phosphonate metabolism
AZC_0704	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AZC_0707	COG0756	dUTP diphosphatase activity
AZC_0710	COG2205	protein histidine kinase activity
AZC_0711	COG3178	'Phosphotransferase
AZC_0712	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AZC_0713	COG2887	Belongs to the helicase family. UvrD subfamily
AZC_0714	COG1074	ATP-dependent DNA helicase activity
AZC_0716	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AZC_0719	COG0840	transmembrane signaling receptor activity
AZC_0721	COG0154	amidase activity
AZC_0722	COG0028	Belongs to the TPP enzyme family
AZC_0728	COG0765	amino acid transport
AZC_0730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZC_0732	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_0740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZC_0741	COG3706	GGDEF domain
AZC_0743	COG2814	Major facilitator Superfamily
AZC_0745	COG0137	argininosuccinate synthase activity
AZC_0752	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AZC_0758	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AZC_0760	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZC_0761	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_0762	COG1116	anion transmembrane transporter activity
AZC_0763	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AZC_0766	COG1454	alcohol dehydrogenase
AZC_0767	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZC_0768	COG2271	Major facilitator Superfamily
AZC_0769	COG0179	Fumarylacetoacetate (FAA) hydrolase
AZC_0771	COG0405	Gamma-glutamyltransferase
AZC_0772	COG4608	Belongs to the ABC transporter superfamily
AZC_0773	COG0444	Belongs to the ABC transporter superfamily
AZC_0775	COG0601	transmembrane transport
AZC_0776	COG0747	negative chemotaxis
AZC_0781	COG1609	Transcriptional regulator
AZC_0784	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AZC_0786	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AZC_0789	COG2351	hydroxyisourate hydrolase activity
AZC_0790	COG2233	PERMEase
AZC_0791	COG0583	DNA-binding transcription factor activity
AZC_0793	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AZC_0796	COG0101	tRNA pseudouridine synthase activity
AZC_0797	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AZC_0798	COG0242	peptide deformylase activity
AZC_0800	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AZC_0802	COG1024	Enoyl-CoA hydratase
AZC_0804	COG1252	NADH dehydrogenase
AZC_0808	COG4608	Belongs to the ABC transporter superfamily
AZC_0809	COG0444	Belongs to the ABC transporter superfamily
AZC_0810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZC_0813	COG0583	DNA-binding transcription factor activity
AZC_0814	COG1522	sequence-specific DNA binding
AZC_0815	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AZC_0816	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZC_0817	COG0765	amino acid transport
AZC_0820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZC_0821	COG0840	transmembrane signaling receptor activity
AZC_0822	COG1304	FMN binding
AZC_0823	COG2186	Transcriptional regulator
AZC_0824	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_0828	COG4974	Belongs to the 'phage' integrase family
AZC_0857	COG3179	chitinase
AZC_0872	COG3549	Plasmid maintenance system killer
AZC_0878	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AZC_0880	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AZC_0883	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AZC_0884	COG0081	regulation of translation
AZC_0885	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AZC_0886	COG0222	ribosome binding
AZC_0887	COG0085	RNA polymerase activity
AZC_0888	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AZC_0890	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
AZC_0897	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AZC_0903	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AZC_0907	COG0142	geranyltranstransferase activity
AZC_0909	COG1742	UPF0060 membrane protein
AZC_0910	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AZC_0914	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AZC_0916	COG0412	Dienelactone hydrolase
AZC_0919	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AZC_0920	COG4208	sulfate ABC transporter
AZC_0921	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AZC_0922	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AZC_0923	COG0175	sulfate reduction
AZC_0925	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AZC_0927	COG0175	sulfate reduction
AZC_0932	COG1024	Enoyl-CoA hydratase
AZC_0936	COG4221	oxidoreductase activity
AZC_0938	COG0628	permease
AZC_0941	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AZC_0942	COG0302	gtp cyclohydrolase
AZC_0944	COG0671	phosphoesterase, PA-phosphatase related
AZC_0945	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AZC_0947	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AZC_0953	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AZC_0955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZC_0956	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZC_0957	COG1376	ErfK ybiS ycfS ynhG family protein
AZC_0959	COG0670	Belongs to the BI1 family
AZC_0965	COG0583	DNA-binding transcription factor activity
AZC_0966	COG2814	Major facilitator Superfamily
AZC_0971	COG2205	protein histidine kinase activity
AZC_0971	COG0784	Response regulator, receiver
AZC_0975	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AZC_0976	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AZC_0977	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AZC_0982	COG0531	amino acid
AZC_0983	COG1982	Orn Lys Arg decarboxylase major
AZC_0984	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AZC_0985	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AZC_0989	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AZC_0993	COG1414	Transcriptional regulator
AZC_0995	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AZC_0998	COG3706	GGDEF domain
AZC_0998	COG0745	RESPONSE REGULATOR receiver
AZC_1001	COG0523	cobalamin synthesis protein
AZC_1002	COG1686	Belongs to the peptidase S11 family
AZC_1003	COG1132	(ABC) transporter
AZC_1005	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AZC_1007	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AZC_1008	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AZC_1009	COG0187	DNA topoisomerase II activity
AZC_1011	COG1376	ErfK ybiS ycfS ynhG family protein
AZC_1012	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AZC_1013	COG0592	DNA-directed DNA polymerase activity
AZC_1014	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AZC_1015	COG0268	Binds directly to 16S ribosomal RNA
AZC_1017	COG0135	phosphoribosylanthranilate isomerase activity
AZC_1018	COG0133	tryptophan synthase activity
AZC_1020	COG0159	tryptophan synthase activity
AZC_1024	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AZC_1025	COG0285	dihydrofolate synthase activity
AZC_1029	COG0752	glycyl-tRNA synthetase alpha subunit
AZC_1032	COG0751	glycine-tRNA ligase activity
AZC_1034	COG3383	formate dehydrogenase (NAD+) activity
AZC_1037	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AZC_1038	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AZC_1039	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AZC_1041	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
AZC_1042	COG2166	iron-sulfur cluster assembly
AZC_1043	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AZC_1044	COG0719	Fe-S assembly protein
AZC_1045	COG0396	ATPase activity
AZC_1046	COG0719	Fe-S assembly protein
AZC_1047	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AZC_1049	COG3604	Transcriptional regulator
AZC_1050	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AZC_1051	COG0450	alkyl hydroperoxide reductase
AZC_1054	COG3585	molybdate ion transport
AZC_1056	COG3639	organic phosphonate transmembrane transporter activity
AZC_1058	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AZC_1059	COG0154	amidase activity
AZC_1063	COG0300	oxidoreductase activity
AZC_1064	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AZC_1065	COG0384	phenazine biosynthesis protein PhzF
AZC_1066	COG1902	pentaerythritol trinitrate reductase activity
AZC_1068	COG2095	MarC family integral membrane protein
AZC_1069	COG0431	NADPH-dependent FMN reductase
AZC_1071	COG0720	synthase
AZC_1072	COG0602	queuosine metabolic process
AZC_1073	COG0346	lactoylglutathione lyase activity
AZC_1074	COG0786	glutamate:sodium symporter activity
AZC_1077	COG1566	PFAM secretion protein HlyD family protein
AZC_1078	COG0840	transmembrane signaling receptor activity
AZC_1079	COG0583	DNA-binding transcription factor activity
AZC_1085	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AZC_1090	COG3152	Membrane
AZC_1091	COG2166	iron-sulfur cluster assembly
AZC_1093	COG2205	protein histidine kinase activity
AZC_1099	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AZC_1102	COG0477	Major facilitator Superfamily
AZC_1103	COG0523	cobalamin synthesis protein
AZC_1108	COG2188	Transcriptional regulator
AZC_1109	COG4695	Portal protein
AZC_1129	COG0745	RESPONSE REGULATOR receiver
AZC_1130	COG2205	protein histidine kinase activity
AZC_1132	COG4235	cytochrome complex assembly
AZC_1133	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AZC_1134	COG1138	Cytochrome C-type biogenesis protein
AZC_1135	COG3088	subunit of a heme lyase
AZC_1136	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AZC_1137	COG0745	RESPONSE REGULATOR receiver
AZC_1139	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AZC_1145	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AZC_1146	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AZC_1147	COG1522	sequence-specific DNA binding
AZC_1148	COG0492	ferredoxin-NADP+ reductase activity
AZC_1149	COG0583	DNA-binding transcription factor activity
AZC_1155	COG1921	L-seryl-tRNASec selenium transferase activity
AZC_1157	COG2864	formate dehydrogenase
AZC_1158	COG0437	4 iron, 4 sulfur cluster binding
AZC_1159	COG3383	formate dehydrogenase (NAD+) activity
AZC_1159	COG0243	molybdopterin cofactor binding
AZC_1160	COG3383	formate dehydrogenase (NAD+) activity
AZC_1160	COG0243	molybdopterin cofactor binding
AZC_1161	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AZC_1162	COG1305	Transglutaminase-like
AZC_1163	COG0709	Synthesizes selenophosphate from selenide and ATP
AZC_1166	COG4191	Histidine kinase
AZC_1170	COG0446	pyridine nucleotide-disulphide oxidoreductase
AZC_1170	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AZC_1176	COG0446	pyridine nucleotide-disulphide oxidoreductase
AZC_1176	COG1902	pentaerythritol trinitrate reductase activity
AZC_1177	COG2181	nitrate reductase activity
AZC_1177	COG0247	lactate metabolic process
AZC_1180	COG0583	DNA-binding transcription factor activity
AZC_1182	COG2851	Citrate transporter
AZC_1184	COG1012	belongs to the aldehyde dehydrogenase family
AZC_1186	COG4176	ABC-type proline glycine betaine transport system permease component
AZC_1187	COG4175	Glycine betaine
AZC_1188	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AZC_1191	COG1522	sequence-specific DNA binding
AZC_1193	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AZC_1194	COG1376	ErfK ybiS ycfS ynhG family protein
AZC_1195	COG0598	Magnesium transport protein CorA
AZC_1196	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_1197	COG0259	pyridoxamine-phosphate oxidase activity
AZC_1199	COG0484	heat shock protein binding
AZC_1200	COG0745	RESPONSE REGULATOR receiver
AZC_1205	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AZC_1206	COG0010	Belongs to the arginase family
AZC_1207	COG0387	Pfam Sodium calcium exchanger
AZC_1209	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AZC_1210	COG5001	Diguanylate cyclase
AZC_1210	COG3706	GGDEF domain
AZC_1210	COG2203	Gaf domain
AZC_1210	COG4251	negative regulation of phosphorylation
AZC_1212	COG0420	3'-5' exonuclease activity
AZC_1216	COG0052	Belongs to the universal ribosomal protein uS2 family
AZC_1217	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AZC_1218	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AZC_1219	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AZC_1220	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AZC_1221	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AZC_1222	COG2203	Gaf domain
AZC_1222	COG5001	Diguanylate cyclase
AZC_1222	COG4251	negative regulation of phosphorylation
AZC_1222	COG3706	GGDEF domain
AZC_1225	COG0840	transmembrane signaling receptor activity
AZC_1227	COG2301	Belongs to the HpcH HpaI aldolase family
AZC_1229	COG0679	Auxin Efflux Carrier
AZC_1232	COG3842	ATPase activity
AZC_1233	COG1177	transmembrane transport
AZC_1234	COG1177	transmembrane transport
AZC_1238	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZC_1241	COG0625	glutathione transferase activity
AZC_1243	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AZC_1244	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AZC_1251	COG1573	uracil-dna glycosylase
AZC_1253	COG1758	RNA polymerase activity
AZC_1254	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AZC_1255	COG2814	Major facilitator Superfamily
AZC_1259	COG0848	biopolymer transport protein
AZC_1261	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AZC_1262	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AZC_1263	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AZC_1263	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AZC_1265	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AZC_1266	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AZC_1267	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AZC_1268	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AZC_1269	COG0640	Transcriptional regulator
AZC_1270	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AZC_1272	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AZC_1274	COG0431	NADPH-dependent FMN reductase
AZC_1277	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_1278	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AZC_1280	COG1309	transcriptional regulator
AZC_1281	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AZC_1281	COG1017	nitric oxide dioxygenase activity
AZC_1283	COG2963	transposase activity
AZC_1284	COG3436	PFAM IS66 Orf2 family protein
AZC_1285	COG2433	Pfam Transposase IS66
AZC_1286	COG1733	regulation of RNA biosynthetic process
AZC_1287	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AZC_1291	COG2207	Transcriptional regulator
AZC_1295	COG0583	DNA-binding transcription factor activity
AZC_1297	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_1299	COG3279	Response regulator of the LytR AlgR family
AZC_1300	COG3275	phosphorelay sensor kinase activity
AZC_1301	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AZC_1303	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AZC_1305	COG2610	gluconate transmembrane transporter activity
AZC_1309	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AZC_1310	COG3002	Belongs to the UPF0753 family
AZC_1311	COG0583	DNA-binding transcription factor activity
AZC_1315	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_1316	COG0583	DNA-binding transcription factor activity
AZC_1319	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_1321	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AZC_1324	COG0583	DNA-binding transcription factor activity
AZC_1325	COG1301	dicarboxylic acid transport
AZC_1326	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AZC_1332	COG3712	iron ion homeostasis
AZC_1339	COG1999	signal sequence binding
AZC_1340	COG1858	cytochrome C peroxidase
AZC_1342	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AZC_1344	COG4191	Histidine kinase
AZC_1347	COG0025	NhaP-type Na H and K H
AZC_1348	COG2140	Oxalate decarboxylase
AZC_1351	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AZC_1351	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AZC_1352	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AZC_1353	COG1294	oxidase, subunit
AZC_1354	COG1271	oxidase subunit
AZC_1355	COG0028	Belongs to the TPP enzyme family
AZC_1356	COG0243	molybdopterin cofactor binding
AZC_1357	COG1566	PFAM secretion protein HlyD family protein
AZC_1360	COG4191	Histidine kinase
AZC_1361	COG4566	intracellular signal transduction
AZC_1362	COG4566	intracellular signal transduction
AZC_1363	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AZC_1365	COG0367	asparagine synthase
AZC_1366	COG0121	glutamine amidotransferase
AZC_1379	COG4221	oxidoreductase activity
AZC_1380	COG0534	Mate efflux family protein
AZC_1386	COG2814	Major facilitator Superfamily
AZC_1387	COG0596	Alpha beta hydrolase
AZC_1389	COG0667	Aldo Keto reductase
AZC_1391	COG1275	C4-dicarboxylate transporter malic acid transport protein
AZC_1392	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AZC_1392	COG2010	Cytochrome c
AZC_1395	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AZC_1398	COG1278	Cold shock
AZC_1400	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AZC_1401	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AZC_1402	COG2080	2 iron, 2 sulfur cluster binding
AZC_1403	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AZC_1407	COG2186	Transcriptional regulator
AZC_1408	COG0129	dihydroxy-acid dehydratase activity
AZC_1411	COG1454	alcohol dehydrogenase
AZC_1412	COG0402	S-adenosylhomocysteine deaminase activity
AZC_1414	COG3485	protocatechuate 3,4-dioxygenase
AZC_1415	COG0277	FAD linked oxidase domain protein
AZC_1416	COG1129	ABC transporter
AZC_1417	COG1172	Belongs to the binding-protein-dependent transport system permease family
AZC_1418	COG4214	carbohydrate transport
AZC_1419	COG1879	ABC-type sugar transport system periplasmic component
AZC_1424	COG2223	nitrite transmembrane transporter activity
AZC_1425	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AZC_1426	COG1140	nitrate reductase beta subunit
AZC_1427	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AZC_1428	COG2181	nitrate reductase activity
AZC_1429	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AZC_1430	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AZC_1431	COG0521	Mo-molybdopterin cofactor biosynthetic process
AZC_1434	COG2132	Multicopper oxidase
AZC_1438	COG0559	Belongs to the binding-protein-dependent transport system permease family
AZC_1440	COG0683	leucine binding
AZC_1441	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AZC_1442	COG3485	protocatechuate 3,4-dioxygenase
AZC_1443	COG3485	protocatechuate 3,4-dioxygenase
AZC_1444	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AZC_1445	COG0583	DNA-binding transcription factor activity
AZC_1450	COG0765	amino acid transport
AZC_1451	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZC_1452	COG1126	abc transporter atp-binding protein
AZC_1453	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AZC_1456	COG2217	Heavy metal translocating P-type atpase
AZC_1457	COG0789	Transcriptional regulator
AZC_1460	COG3548	integral membrane protein
AZC_1466	COG0328	RNA-DNA hybrid ribonuclease activity
AZC_1467	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AZC_1468	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AZC_1471	COG0589	response to stress
AZC_1472	COG0463	Glycosyl transferase, family 2
AZC_1475	COG4178	(ABC) transporter
AZC_1476	COG0318	PFAM AMP-dependent synthetase and ligase
AZC_1482	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZC_1483	COG2135	peptidase activity
AZC_1489	COG0477	Major facilitator Superfamily
AZC_1490	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_1494	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AZC_1494	COG0446	pyridine nucleotide-disulphide oxidoreductase
AZC_1496	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZC_1497	COG4977	sequence-specific DNA binding
AZC_1500	COG0069	glutamate synthase activity
AZC_1501	COG2218	PFAM glutamate synthase alpha subunit domain protein
AZC_1502	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AZC_1507	COG5265	(ABC) transporter
AZC_1509	COG0688	phosphatidylethanolamine metabolic process
AZC_1510	COG1183	phosphatidylcholine synthase activity
AZC_1512	COG0601	transmembrane transport
AZC_1513	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZC_1514	COG4172	Belongs to the ABC transporter superfamily
AZC_1517	COG1802	Transcriptional regulator
AZC_1524	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZC_1525	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AZC_1526	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AZC_1529	COG0328	RNA-DNA hybrid ribonuclease activity
AZC_1531	COG1024	Enoyl-CoA hydratase
AZC_1533	COG0730	response to heat
AZC_1535	COG1703	isobutyryl-CoA mutase activity
AZC_1540	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AZC_1543	COG0113	porphobilinogen synthase activity
AZC_1544	COG1024	Enoyl-CoA hydratase
AZC_1549	COG0444	Belongs to the ABC transporter superfamily
AZC_1550	COG0154	amidase activity
AZC_1551	COG4608	Belongs to the ABC transporter superfamily
AZC_1552	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZC_1554	COG4166	transmembrane transport
AZC_1558	COG1216	Glycosyl transferase, family 2
AZC_1565	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AZC_1567	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AZC_1568	COG2205	protein histidine kinase activity
AZC_1580	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AZC_1581	COG0671	phosphoesterase, PA-phosphatase related
AZC_1582	COG0463	Glycosyl transferase, family 2
AZC_1584	COG0626	cystathionine gamma-synthase activity
AZC_1585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZC_1586	COG4597	amino acid ABC transporter
AZC_1587	COG0765	amino acid transport
AZC_1588	COG1126	abc transporter atp-binding protein
AZC_1589	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AZC_1591	COG0484	heat shock protein binding
AZC_1592	COG1686	Belongs to the peptidase S11 family
AZC_1594	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AZC_1597	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AZC_1601	COG0174	glutamine synthetase
AZC_1602	COG0347	Belongs to the P(II) protein family
AZC_1603	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AZC_1603	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AZC_1605	COG0667	Aldo Keto reductase
AZC_1606	COG0583	DNA-binding transcription factor activity
AZC_1607	COG0544	peptidyl-prolyl cis-trans isomerase activity
AZC_1608	COG0740	serine-type endopeptidase activity
AZC_1609	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AZC_1610	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AZC_1611	COG0776	regulation of translation
AZC_1613	COG2814	Major facilitator Superfamily
AZC_1614	COG0418	dihydroorotase activity
AZC_1617	COG3685	Protein conserved in bacteria
AZC_1620	COG1607	acyl-coa hydrolase
AZC_1621	COG1132	(ABC) transporter
AZC_1625	COG1120	ATPase activity
AZC_1626	COG4774	siderophore transport
AZC_1631	COG0179	Fumarylacetoacetate (FAA) hydrolase
AZC_1632	COG1629	transport
AZC_1632	COG4206	TonB-dependent receptor
AZC_1633	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AZC_1636	COG2186	Transcriptional regulator
AZC_1637	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AZC_1645	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AZC_1647	COG2076	Multidrug Resistance protein
AZC_1652	COG3852	Histidine kinase
AZC_1653	COG2204	response regulator
AZC_1656	COG3956	TIGRFAM MazG family protein
AZC_1659	COG3768	UPF0283 membrane protein
AZC_1660	COG3106	COG3106 Predicted ATPase
AZC_1664	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AZC_1668	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AZC_1669	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AZC_1670	COG0649	NAD binding
AZC_1671	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AZC_1672	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AZC_1675	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AZC_1676	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AZC_1678	COG0713	ATP synthesis coupled electron transport
AZC_1681	COG1007	ATP synthesis coupled electron transport
AZC_1684	COG0346	lactoylglutathione lyase activity
AZC_1686	COG0442	prolyl-tRNA aminoacylation
AZC_1688	COG1136	(ABC) transporter
AZC_1691	COG0587	DNA-directed DNA polymerase activity
AZC_1693	COG0052	Belongs to the universal ribosomal protein uS2 family
AZC_1694	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AZC_1695	COG0528	UMP kinase activity
AZC_1696	COG0233	cytoplasmic translational termination
AZC_1697	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AZC_1700	COG0750	zinc metalloprotease
AZC_1701	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AZC_1702	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AZC_1703	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AZC_1704	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AZC_1705	COG3494	Protein of unknown function (DUF1009)
AZC_1706	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AZC_1707	COG0583	DNA-binding transcription factor activity
AZC_1708	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_1710	COG0372	Belongs to the citrate synthase family
AZC_1711	COG0746	molybdenum cofactor guanylyltransferase activity
AZC_1718	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AZC_1719	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AZC_1724	COG2832	Protein of unknown function (DUF454)
AZC_1728	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AZC_1732	COG1472	Belongs to the glycosyl hydrolase 3 family
AZC_1733	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AZC_1734	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AZC_1735	COG3842	ATPase activity
AZC_1736	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AZC_1737	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AZC_1738	COG0805	protein transport
AZC_1739	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AZC_1741	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AZC_1743	COG0022	dehydrogenase e1 component
AZC_1743	COG0508	dehydrogenase complex catalyzes the overall conversion of
AZC_1744	COG0508	dehydrogenase complex catalyzes the overall conversion of
AZC_1746	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AZC_1747	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AZC_1748	COG2867	negative regulation of translational initiation
AZC_1749	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AZC_1750	COG1253	flavin adenine dinucleotide binding
AZC_1754	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AZC_1756	COG2239	Acts as a magnesium transporter
AZC_1759	COG0559	Belongs to the binding-protein-dependent transport system permease family
AZC_1761	COG0411	ABC transporter
AZC_1763	COG0829	nickel cation binding
AZC_1764	COG0831	urea catabolic process
AZC_1764	COG0832	Belongs to the urease beta subunit family
AZC_1766	COG0804	urea catabolic process
AZC_1767	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AZC_1768	COG0830	nickel cation binding
AZC_1769	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AZC_1775	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AZC_1776	COG1396	sequence-specific DNA binding
AZC_1776	COG3800	Transcriptional regulator
AZC_1781	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AZC_1782	COG3045	CreA protein
AZC_1784	COG0215	cysteine-tRNA ligase activity
AZC_1786	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AZC_1793	COG0288	reversible hydration of carbon dioxide
AZC_1800	COG1176	ABC-type spermidine putrescine transport system, permease component I
AZC_1801	COG3842	ATPase activity
AZC_1803	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AZC_1804	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AZC_1807	COG1764	response to oxidative stress
AZC_1808	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AZC_1809	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AZC_1811	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AZC_1812	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AZC_1815	COG0537	adenosine 5'-monophosphoramidase activity
AZC_1818	COG2308	Evidence 4 Homologs of previously reported genes of
AZC_1819	COG1546	Belongs to the CinA family
AZC_1819	COG1058	Belongs to the CinA family
AZC_1821	COG3909	cytochrome
AZC_1824	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AZC_1826	COG0351	phosphomethylpyrimidine kinase
AZC_1827	COG1396	sequence-specific DNA binding
AZC_1830	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AZC_1832	COG1091	dTDP-4-dehydrorhamnose reductase activity
AZC_1833	COG1088	dTDP-glucose 4,6-dehydratase activity
AZC_1838	COG0765	amino acid transport
AZC_1839	COG1126	abc transporter atp-binding protein
AZC_1840	COG2267	carboxylic ester hydrolase activity
AZC_1841	COG2301	Belongs to the HpcH HpaI aldolase family
AZC_1843	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AZC_1844	COG0583	DNA-binding transcription factor activity
AZC_1845	COG3243	poly(R)-hydroxyalkanoic acid synthase
AZC_1847	COG0436	Aminotransferase
AZC_1852	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AZC_1854	COG0784	Response regulator, receiver
AZC_1855	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AZC_1859	COG0557	exoribonuclease II activity
AZC_1860	COG0477	Major facilitator Superfamily
AZC_1861	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AZC_1864	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AZC_1865	COG0538	isocitrate dehydrogenase activity
AZC_1869	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZC_1870	COG0601	transmembrane transport
AZC_1871	COG0747	negative chemotaxis
AZC_1873	COG0583	DNA-binding transcription factor activity
AZC_1875	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AZC_1876	COG2030	dehydratase
AZC_1878	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AZC_1879	COG1802	Transcriptional regulator
AZC_1882	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AZC_1883	COG0179	Fumarylacetoacetate (FAA) hydrolase
AZC_1886	COG0411	ABC transporter
AZC_1892	COG2084	Dehydrogenase
AZC_1894	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AZC_1895	COG0583	DNA-binding transcription factor activity
AZC_1896	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AZC_1898	COG3610	response to peptide
AZC_1899	COG0579	oxidoreductase
AZC_1901	COG0114	fumarate hydratase activity
AZC_1904	COG2271	Major facilitator Superfamily
AZC_1906	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_1907	COG0508	dehydrogenase complex catalyzes the overall conversion of
AZC_1907	COG0596	Alpha beta hydrolase
AZC_1908	COG0022	dehydrogenase e1 component
AZC_1909	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AZC_1910	COG3199	ATP-NAD kinase
AZC_1911	COG3284	Transcriptional regulator
AZC_1913	COG4771	TonB-dependent receptor
AZC_1917	COG1012	belongs to the aldehyde dehydrogenase family
AZC_1924	COG1126	abc transporter atp-binding protein
AZC_1925	COG0765	amino acid transport
AZC_1926	COG0765	amino acid transport
AZC_1927	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZC_1928	COG0583	DNA-binding transcription factor activity
AZC_1932	COG2963	transposase activity
AZC_1935	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AZC_1936	COG1278	Cold shock
AZC_1942	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_1944	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZC_1948	COG0477	Major facilitator Superfamily
AZC_1949	COG0583	DNA-binding transcription factor activity
AZC_1951	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_1958	COG0601	transmembrane transport
AZC_1959	COG0747	negative chemotaxis
AZC_1960	COG2072	flavoprotein involved in K transport
AZC_1961	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_1968	COG2351	hydroxyisourate hydrolase activity
AZC_1970	COG1176	ABC-type spermidine putrescine transport system, permease component I
AZC_1971	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AZC_1972	COG3842	ATPase activity
AZC_1974	COG2186	Transcriptional regulator
AZC_1975	COG1454	alcohol dehydrogenase
AZC_1977	COG1116	anion transmembrane transporter activity
AZC_1978	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_1980	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_1981	COG4957	zinc ion binding
AZC_1982	COG4608	Belongs to the ABC transporter superfamily
AZC_1983	COG0444	Belongs to the ABC transporter superfamily
AZC_1984	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZC_1986	COG0747	negative chemotaxis
AZC_1987	COG1473	amidohydrolase
AZC_1989	COG1177	transmembrane transport
AZC_1990	COG1176	ABC-type spermidine putrescine transport system, permease component I
AZC_1991	COG3842	ATPase activity
AZC_1992	COG1840	ABC-type Fe3 transport system, periplasmic component
AZC_1998	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AZC_2001	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AZC_2002	COG0736	holo-[acyl-carrier-protein] synthase activity
AZC_2003	COG0681	Belongs to the peptidase S26 family
AZC_2004	COG0571	ribonuclease III activity
AZC_2005	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AZC_2006	COG1381	Involved in DNA repair and RecF pathway recombination
AZC_2007	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AZC_2008	COG0038	chloride channel
AZC_2009	COG0235	Class ii aldolase
AZC_2010	COG2423	ornithine cyclodeaminase activity
AZC_2011	COG4608	Belongs to the ABC transporter superfamily
AZC_2012	COG0444	Belongs to the ABC transporter superfamily
AZC_2013	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZC_2014	COG0601	transmembrane transport
AZC_2015	COG0747	negative chemotaxis
AZC_2016	COG3964	amidohydrolase
AZC_2020	COG0154	amidase activity
AZC_2021	COG2271	Major facilitator Superfamily
AZC_2027	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZC_2028	COG0601	transmembrane transport
AZC_2029	COG0747	negative chemotaxis
AZC_2034	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZC_2035	COG1012	belongs to the aldehyde dehydrogenase family
AZC_2036	COG1012	belongs to the aldehyde dehydrogenase family
AZC_2042	COG0154	amidase activity
AZC_2045	COG0747	negative chemotaxis
AZC_2046	COG0601	transmembrane transport
AZC_2047	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZC_2048	COG4172	Belongs to the ABC transporter superfamily
AZC_2050	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_2053	COG2514	catechol 2,3-dioxygenase activity
AZC_2054	COG0435	Glutathione S-transferase
AZC_2056	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZC_2057	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_2058	COG1116	anion transmembrane transporter activity
AZC_2061	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_2062	COG0318	PFAM AMP-dependent synthetase and ligase
AZC_2065	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AZC_2066	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZC_2067	COG1522	sequence-specific DNA binding
AZC_2068	COG1280	lysine exporter protein (LysE YggA)
AZC_2069	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZC_2070	COG1126	abc transporter atp-binding protein
AZC_2071	COG0765	amino acid transport
AZC_2073	COG1396	sequence-specific DNA binding
AZC_2075	COG1473	amidohydrolase
AZC_2077	COG4172	Belongs to the ABC transporter superfamily
AZC_2078	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZC_2079	COG0601	transmembrane transport
AZC_2080	COG0747	negative chemotaxis
AZC_2086	COG0640	Transcriptional regulator
AZC_2087	COG0477	Major facilitator Superfamily
AZC_2096	COG0671	phosphoesterase, PA-phosphatase related
AZC_2097	COG0477	Major facilitator Superfamily
AZC_2098	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AZC_2099	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AZC_2100	COG1845	cytochrome c oxidase, subunit III
AZC_2101	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AZC_2104	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AZC_2105	COG1053	succinate dehydrogenase
AZC_2106	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AZC_2108	COG2188	Transcriptional regulator
AZC_2120	COG1335	isochorismatase
AZC_2132	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AZC_2142	COG4373	Mu-like prophage FluMu protein gp28
AZC_2149	COG4397	Mu-like prophage major head subunit gpT
AZC_2172	COG1686	Belongs to the peptidase S11 family
AZC_2173	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AZC_2174	COG0470	DNA polymerase III
AZC_2176	COG3181	Tripartite tricarboxylate transporter family receptor
AZC_2177	COG1268	BioY protein
AZC_2178	COG0084	hydrolase, TatD family'
AZC_2181	COG0583	DNA-binding transcription factor activity
AZC_2182	COG1380	Effector of murein hydrolase LrgA
AZC_2183	COG1346	cytolysis
AZC_2184	COG1612	heme a metabolic process
AZC_2187	COG1024	Enoyl-CoA hydratase
AZC_2189	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AZC_2190	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AZC_2191	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AZC_2194	COG0667	Aldo Keto reductase
AZC_2197	COG1473	amidohydrolase
AZC_2199	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AZC_2201	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AZC_2202	COG0303	'Molybdopterin
AZC_2203	COG0315	cyclic pyranopterin monophosphate synthase activity
AZC_2205	COG0134	indole-3-glycerol-phosphate synthase activity
AZC_2206	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AZC_2208	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AZC_2212	COG4948	Mandelate Racemase Muconate Lactonizing
AZC_2213	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AZC_2214	COG1127	ABC transporter
AZC_2219	COG0633	Ferredoxin
AZC_2220	COG0463	Glycosyl transferase, family 2
AZC_2222	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AZC_2224	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AZC_2225	COG1285	pathogenesis
AZC_2228	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AZC_2229	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AZC_2230	COG0047	phosphoribosylformylglycinamidine synthase activity
AZC_2231	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AZC_2237	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AZC_2240	COG0612	Peptidase, M16
AZC_2241	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AZC_2243	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AZC_2245	COG1840	ABC-type Fe3 transport system, periplasmic component
AZC_2248	COG2205	protein histidine kinase activity
AZC_2252	COG0859	PFAM glycosyl transferase family 9
AZC_2253	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AZC_2254	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AZC_2254	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AZC_2255	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AZC_2258	COG1492	cobalamin metabolic process
AZC_2260	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AZC_2261	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AZC_2263	COG1238	metal cluster binding
AZC_2264	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AZC_2264	COG0321	lipoyl(octanoyl) transferase activity
AZC_2266	COG1280	lysine exporter protein (LysE YggA)
AZC_2267	COG1304	FMN binding
AZC_2269	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_2270	COG0179	Fumarylacetoacetate (FAA) hydrolase
AZC_2271	COG4948	Mandelate Racemase Muconate Lactonizing
AZC_2272	COG2271	Major facilitator Superfamily
AZC_2276	COG1116	anion transmembrane transporter activity
AZC_2277	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZC_2278	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_2281	COG4566	intracellular signal transduction
AZC_2282	COG4566	intracellular signal transduction
AZC_2285	COG3685	Protein conserved in bacteria
AZC_2287	COG3655	Transcriptional regulator
AZC_2291	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AZC_2293	COG0776	regulation of translation
AZC_2294	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AZC_2295	COG0416	fatty acid biosynthetic process
AZC_2300	COG0438	transferase activity, transferring glycosyl groups
AZC_2302	COG0179	Fumarylacetoacetate (FAA) hydrolase
AZC_2303	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AZC_2306	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AZC_2307	COG0343	queuine tRNA-ribosyltransferase activity
AZC_2308	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AZC_2309	COG3932	Exopolysaccharide synthesis, ExoD
AZC_2310	COG5425	PFAM Usg family protein
AZC_2311	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AZC_2312	COG0459	protein refolding
AZC_2316	COG1254	Belongs to the acylphosphatase family
AZC_2323	COG0563	adenylate kinase activity
AZC_2325	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AZC_2326	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AZC_2327	COG1280	lysine exporter protein (LysE YggA)
AZC_2330	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AZC_2332	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AZC_2333	COG2814	Major facilitator Superfamily
AZC_2335	COG0438	transferase activity, transferring glycosyl groups
AZC_2335	COG1216	Glycosyl transferase, family 2
AZC_2336	COG1414	Transcriptional regulator
AZC_2337	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZC_2341	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_2343	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AZC_2345	COG1309	transcriptional regulator
AZC_2348	COG0673	inositol 2-dehydrogenase activity
AZC_2350	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AZC_2351	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZC_2352	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_2356	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AZC_2358	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AZC_2359	COG0546	phosphoglycolate phosphatase activity
AZC_2360	COG1376	ErfK ybiS ycfS ynhG family protein
AZC_2361	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZC_2362	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_2365	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AZC_2366	COG0513	Belongs to the DEAD box helicase family
AZC_2367	COG0586	Pfam SNARE associated Golgi protein
AZC_2368	COG0725	ABC transporter, periplasmic molybdate-binding protein
AZC_2369	COG4149	molybdate abc transporter
AZC_2370	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AZC_2373	COG0716	FMN binding
AZC_2374	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AZC_2376	COG0028	Belongs to the TPP enzyme family
AZC_2378	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AZC_2379	COG0483	inositol monophosphate 1-phosphatase activity
AZC_2382	COG1519	Transferase
AZC_2383	COG1663	tetraacyldisaccharide 4'-kinase activity
AZC_2385	COG1570	exodeoxyribonuclease VII activity
AZC_2386	COG0151	Belongs to the GarS family
AZC_2387	COG0596	Alpha beta hydrolase
AZC_2389	COG0590	tRNA wobble adenosine to inosine editing
AZC_2390	COG1187	pseudouridine synthase activity
AZC_2391	COG0742	ribosomal rna small subunit methyltransferase
AZC_2392	COG0668	transmembrane transport
AZC_2393	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AZC_2395	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AZC_2396	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AZC_2398	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AZC_2399	COG2321	neutral zinc metallopeptidase
AZC_2400	COG0521	Mo-molybdopterin cofactor biosynthetic process
AZC_2402	COG1960	acyl-CoA dehydrogenase activity
AZC_2403	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AZC_2404	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AZC_2405	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AZC_2406	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AZC_2409	COG1560	Kdo2-lipid A biosynthetic process
AZC_2412	COG3706	GGDEF domain
AZC_2414	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AZC_2415	COG0840	transmembrane signaling receptor activity
AZC_2416	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AZC_2418	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AZC_2421	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AZC_2424	COG0129	dihydroxy-acid dehydratase activity
AZC_2425	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AZC_2431	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AZC_2432	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
AZC_2436	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
AZC_2438	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AZC_2441	COG2267	carboxylic ester hydrolase activity
AZC_2442	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AZC_2443	COG0300	oxidoreductase activity
AZC_2447	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZC_2448	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_2452	COG3795	YCII-related domain
AZC_2453	COG4941	Belongs to the sigma-70 factor family
AZC_2454	COG1802	Transcriptional regulator
AZC_2457	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AZC_2460	COG3842	ATPase activity
AZC_2461	COG4208	sulfate ABC transporter
AZC_2462	COG1176	ABC-type spermidine putrescine transport system, permease component I
AZC_2465	COG0583	DNA-binding transcription factor activity
AZC_2466	COG0840	transmembrane signaling receptor activity
AZC_2466	COG0840	transmembrane signaling receptor activity
AZC_2467	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AZC_2467	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AZC_2469	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_2470	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_2473	COG1846	Transcriptional regulator
AZC_2474	COG0277	FAD linked oxidase domain protein
AZC_2477	COG1176	ABC-type spermidine putrescine transport system, permease component I
AZC_2478	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AZC_2483	COG2186	Transcriptional regulator
AZC_2486	COG0765	amino acid transport
AZC_2487	COG0765	amino acid transport
AZC_2489	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AZC_2491	COG0583	DNA-binding transcription factor activity
AZC_2492	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZC_2493	COG1335	isochorismatase
AZC_2494	COG0251	oxidation-reduction process
AZC_2495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_2496	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AZC_2497	COG1116	anion transmembrane transporter activity
AZC_2498	COG0583	DNA-binding transcription factor activity
AZC_2500	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AZC_2501	COG1024	Enoyl-CoA hydratase
AZC_2503	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_2506	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_2507	COG2203	Gaf domain
AZC_2507	COG3706	GGDEF domain
AZC_2507	COG4251	negative regulation of phosphorylation
AZC_2507	COG5001	Diguanylate cyclase
AZC_2508	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
AZC_2510	COG2610	gluconate transmembrane transporter activity
AZC_2511	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AZC_2512	COG2199	diguanylate cyclase activity
AZC_2512	COG2203	Gaf domain
AZC_2513	COG0187	DNA topoisomerase II activity
AZC_2515	COG0513	Belongs to the DEAD box helicase family
AZC_2516	COG3706	GGDEF domain
AZC_2517	COG3706	GGDEF domain
AZC_2520	COG0546	phosphoglycolate phosphatase activity
AZC_2522	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AZC_2525	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AZC_2527	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AZC_2528	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AZC_2529	COG0203	ribosomal protein L17
AZC_2530	COG0202	RNA polymerase activity
AZC_2531	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AZC_2532	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AZC_2533	COG0563	adenylate kinase activity
AZC_2535	COG0200	Binds to the 23S rRNA
AZC_2536	COG1841	ribosomal large subunit assembly
AZC_2537	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AZC_2538	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AZC_2539	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AZC_2540	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AZC_2541	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AZC_2542	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AZC_2543	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AZC_2544	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AZC_2545	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AZC_2546	COG0255	Belongs to the universal ribosomal protein uL29 family
AZC_2547	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AZC_2548	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AZC_2549	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AZC_2550	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AZC_2551	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AZC_2552	COG0089	rRNA binding
AZC_2553	COG0088	Forms part of the polypeptide exit tunnel
AZC_2554	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AZC_2555	COG0051	transcription antitermination factor activity, RNA binding
AZC_2556	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AZC_2557	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AZC_2558	COG0049	tRNA binding
AZC_2559	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AZC_2561	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AZC_2562	COG1704	LemA family
AZC_2563	COG2827	Endonuclease containing a URI domain
AZC_2566	COG0114	fumarate hydratase activity
AZC_2570	COG0330	HflC and HflK could
AZC_2573	COG0840	transmembrane signaling receptor activity
AZC_2574	COG0560	Phosphoserine phosphatase
AZC_2575	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AZC_2576	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AZC_2577	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
AZC_2578	COG0154	amidase activity
AZC_2579	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_2581	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZC_2582	COG0515	serine threonine protein kinase
AZC_2582	COG2815	serine threonine protein kinase
AZC_2583	COG0631	protein serine/threonine phosphatase activity
AZC_2592	COG3501	Rhs element vgr protein
AZC_2606	COG0500	methyltransferase
AZC_2609	COG0251	oxidation-reduction process
AZC_2610	COG2084	Dehydrogenase
AZC_2611	COG1609	Transcriptional regulator
AZC_2613	COG1063	alcohol dehydrogenase
AZC_2614	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_2615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZC_2617	COG0765	amino acid transport
AZC_2619	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AZC_2620	COG2706	6-phosphogluconolactonase activity
AZC_2623	COG0154	amidase activity
AZC_2624	COG0154	amidase activity
AZC_2626	COG4166	transmembrane transport
AZC_2629	COG4608	Belongs to the ABC transporter superfamily
AZC_2630	COG0444	Belongs to the ABC transporter superfamily
AZC_2632	COG0154	amidase activity
AZC_2633	COG0154	amidase activity
AZC_2634	COG0154	amidase activity
AZC_2636	COG2721	sulfolactate sulfo-lyase activity
AZC_2637	COG1012	belongs to the aldehyde dehydrogenase family
AZC_2638	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AZC_2639	COG0583	DNA-binding transcription factor activity
AZC_2640	COG2271	Major facilitator Superfamily
AZC_2641	COG0628	permease
AZC_2642	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AZC_2644	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_2649	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AZC_2650	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_2654	COG4608	Belongs to the ABC transporter superfamily
AZC_2657	COG1309	transcriptional regulator
AZC_2660	COG0601	transmembrane transport
AZC_2661	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZC_2664	COG0667	Aldo Keto reductase
AZC_2665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZC_2671	COG0583	DNA-binding transcription factor activity
AZC_2672	COG2828	Protein conserved in bacteria
AZC_2673	COG1301	dicarboxylic acid transport
AZC_2676	COG1278	Cold shock
AZC_2677	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AZC_2680	COG0765	amino acid transport
AZC_2681	COG0765	amino acid transport
AZC_2687	COG1850	ribulose-bisphosphate carboxylase activity
AZC_2689	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AZC_2690	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AZC_2692	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AZC_2693	COG0154	amidase activity
AZC_2694	COG4608	Belongs to the ABC transporter superfamily
AZC_2697	COG0601	transmembrane transport
AZC_2698	COG0747	negative chemotaxis
AZC_2699	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AZC_2707	COG0726	polysaccharide deacetylase
AZC_2710	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AZC_2711	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AZC_2713	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZC_2715	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AZC_2716	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_2717	COG3706	GGDEF domain
AZC_2721	COG1414	Transcriptional regulator
AZC_2722	COG1176	ABC-type spermidine putrescine transport system, permease component I
AZC_2723	COG1177	transmembrane transport
AZC_2725	COG3842	ATPase activity
AZC_2730	COG0402	S-adenosylhomocysteine deaminase activity
AZC_2731	COG0583	DNA-binding transcription factor activity
AZC_2733	COG0765	amino acid transport
AZC_2734	COG1126	abc transporter atp-binding protein
AZC_2737	COG0747	negative chemotaxis
AZC_2740	COG4977	sequence-specific DNA binding
AZC_2742	COG3046	protein related to deoxyribodipyrimidine photolyase
AZC_2743	COG0672	)-iron permease
AZC_2745	COG2132	Multicopper oxidase
AZC_2749	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AZC_2751	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AZC_2751	COG1017	nitric oxide dioxygenase activity
AZC_2757	COG5265	(ABC) transporter
AZC_2758	COG0438	transferase activity, transferring glycosyl groups
AZC_2763	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AZC_2763	COG0574	Belongs to the PEP-utilizing enzyme family
AZC_2765	COG3706	GGDEF domain
AZC_2768	COG1312	Catalyzes the dehydration of D-mannonate
AZC_2769	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AZC_2772	COG0318	PFAM AMP-dependent synthetase and ligase
AZC_2773	COG1522	sequence-specific DNA binding
AZC_2775	COG3395	kinase activity
AZC_2776	COG3622	Belongs to the hyi family
AZC_2777	COG2084	Dehydrogenase
AZC_2778	COG1609	Transcriptional regulator
AZC_2779	COG0235	Class ii aldolase
AZC_2781	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AZC_2788	COG0477	Major facilitator Superfamily
AZC_2789	COG1396	sequence-specific DNA binding
AZC_2790	COG1846	Transcriptional regulator
AZC_2800	COG2080	2 iron, 2 sulfur cluster binding
AZC_2801	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AZC_2801	COG2010	Cytochrome c
AZC_2802	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AZC_2806	COG0018	arginyl-trna synthetase
AZC_2807	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AZC_2808	COG0316	Belongs to the HesB IscA family
AZC_2811	COG1696	Membrane protein involved in D-alanine export
AZC_2815	COG0525	valine-tRNA ligase activity
AZC_2818	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AZC_2820	COG1132	(ABC) transporter
AZC_2824	COG0415	Belongs to the DNA photolyase family
AZC_2825	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AZC_2826	COG2897	thiosulfate sulfurtransferase activity
AZC_2827	COG0840	transmembrane signaling receptor activity
AZC_2828	COG0840	transmembrane signaling receptor activity
AZC_2833	COG1960	acyl-CoA dehydrogenase activity
AZC_2834	COG5001	Diguanylate cyclase
AZC_2835	COG2239	Acts as a magnesium transporter
AZC_2837	COG0726	polysaccharide deacetylase
AZC_2839	COG0321	lipoyl(octanoyl) transferase activity
AZC_2840	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AZC_2841	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AZC_2842	COG0514	ATP-dependent DNA helicase (RecQ)
AZC_2843	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AZC_2844	COG0154	amidase activity
AZC_2847	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AZC_2848	COG0758	DNA mediated transformation
AZC_2849	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AZC_2850	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AZC_2851	COG0540	Belongs to the ATCase OTCase family
AZC_2854	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AZC_2855	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AZC_2858	COG2271	Major facilitator Superfamily
AZC_2860	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AZC_2863	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AZC_2864	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AZC_2866	COG1024	Enoyl-CoA hydratase
AZC_2868	COG0410	ABC transporter
AZC_2869	COG0411	ABC transporter
AZC_2871	COG0559	Belongs to the binding-protein-dependent transport system permease family
AZC_2873	COG1024	Enoyl-CoA hydratase
AZC_2873	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZC_2874	COG0318	PFAM AMP-dependent synthetase and ligase
AZC_2875	COG0183	Belongs to the thiolase family
AZC_2876	COG1960	acyl-CoA dehydrogenase activity
AZC_2877	COG1960	acyl-CoA dehydrogenase activity
AZC_2879	COG0477	Major facilitator Superfamily
AZC_2881	COG3246	L-lysine catabolic process to acetate
AZC_2882	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AZC_2883	COG0179	Fumarylacetoacetate (FAA) hydrolase
AZC_2884	COG1414	Transcriptional regulator
AZC_2886	COG0629	single-stranded DNA binding
AZC_2887	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AZC_2889	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AZC_2892	COG3737	Protein of unknown function (DUF498/DUF598)
AZC_2894	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AZC_2896	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AZC_2900	COG0656	L-ascorbic acid biosynthetic process
AZC_2901	COG3979	chitinase
AZC_2904	COG1012	belongs to the aldehyde dehydrogenase family
AZC_2906	COG0583	DNA-binding transcription factor activity
AZC_2907	COG4608	Belongs to the ABC transporter superfamily
AZC_2909	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZC_2914	COG0501	Belongs to the peptidase M48B family
AZC_2921	COG4647	ligase activity
AZC_2922	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
AZC_2923	COG0145	ligase activity
AZC_2927	COG0625	glutathione transferase activity
AZC_2928	COG1509	lysine 2,3-aminomutase activity
AZC_2930	COG3608	succinylglutamate desuccinylase aspartoacylase
AZC_2930	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AZC_2932	COG2814	Major facilitator Superfamily
AZC_2935	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AZC_2947	COG0683	leucine binding
AZC_2949	COG0785	Cytochrome C biogenesis protein
AZC_2950	COG3191	aminopeptidase activity
AZC_2952	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZC_2953	COG3346	SURF1 family
AZC_2956	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AZC_2958	COG0109	protoheme IX farnesyltransferase activity
AZC_2959	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AZC_2960	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AZC_2966	COG0583	DNA-binding transcription factor activity
AZC_2968	COG0628	permease
AZC_2969	COG0318	PFAM AMP-dependent synthetase and ligase
AZC_2972	COG0183	Belongs to the thiolase family
AZC_2973	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZC_2973	COG1024	Enoyl-CoA hydratase
AZC_2974	COG1960	acyl-CoA dehydrogenase activity
AZC_2977	COG1764	response to oxidative stress
AZC_2978	COG0477	Major facilitator Superfamily
AZC_2981	COG0840	transmembrane signaling receptor activity
AZC_2983	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AZC_2985	COG1785	Belongs to the alkaline phosphatase family
AZC_2989	COG0667	Aldo Keto reductase
AZC_2990	COG1446	asparaginase
AZC_2991	COG2362	D-Aminopeptidase
AZC_2993	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZC_2995	COG0747	negative chemotaxis
AZC_2996	COG4172	Belongs to the ABC transporter superfamily
AZC_2999	COG1228	amidohydrolase
AZC_3008	COG1283	sodium-dependent phosphate transmembrane transporter activity
AZC_3011	COG1393	Belongs to the ArsC family
AZC_3012	COG2204	response regulator
AZC_3013	COG4191	Histidine kinase
AZC_3014	COG1301	dicarboxylic acid transport
AZC_3016	COG0861	Integral membrane protein TerC family
AZC_3018	COG0583	DNA-binding transcription factor activity
AZC_3019	COG1982	Orn Lys Arg decarboxylase major
AZC_3022	COG0528	UMP kinase activity
AZC_3023	COG0528	UMP kinase activity
AZC_3025	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AZC_3027	COG2226	methyltransferase
AZC_3028	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AZC_3029	COG3179	chitinase
AZC_3032	COG2059	Chromate
AZC_3036	COG0387	Pfam Sodium calcium exchanger
AZC_3037	COG0165	Argininosuccinate lyase
AZC_3038	COG1414	Transcriptional regulator
AZC_3050	COG1760	l-serine dehydratase
AZC_3051	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AZC_3053	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AZC_3059	COG0433	COG0433 Predicted ATPase
AZC_3061	COG0148	phosphopyruvate hydratase activity
AZC_3062	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AZC_3064	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AZC_3065	COG2076	Multidrug Resistance protein
AZC_3067	COG0504	CTP synthase activity
AZC_3069	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AZC_3073	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AZC_3074	COG0511	ligase activity, forming carbon-carbon bonds
AZC_3076	COG1116	anion transmembrane transporter activity
AZC_3079	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AZC_3080	COG1923	regulation of RNA biosynthetic process
AZC_3082	COG0569	domain protein
AZC_3083	COG2204	response regulator
AZC_3084	COG5000	phosphorelay sensor kinase activity
AZC_3085	COG2199	diguanylate cyclase activity
AZC_3085	COG2200	EAL domain
AZC_3085	COG2203	Gaf domain
AZC_3086	COG2204	response regulator
AZC_3089	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AZC_3089	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AZC_3090	COG1546	Belongs to the CinA family
AZC_3090	COG1058	Belongs to the CinA family
AZC_3091	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AZC_3094	COG4566	intracellular signal transduction
AZC_3097	COG0477	Major facilitator Superfamily
AZC_3098	COG4191	Histidine kinase
AZC_3101	COG1335	isochorismatase
AZC_3102	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AZC_3102	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AZC_3104	COG3781	membrane
AZC_3106	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AZC_3107	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AZC_3111	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AZC_3112	COG3754	Rhamnan synthesis protein F
AZC_3116	COG1722	exodeoxyribonuclease VII activity
AZC_3118	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AZC_3120	COG0308	aminopeptidase N
AZC_3121	COG0583	DNA-binding transcription factor activity
AZC_3122	COG2205	protein histidine kinase activity
AZC_3122	COG2202	Pas domain
AZC_3125	COG1618	nucleotide phosphatase activity, acting on free nucleotides
AZC_3125	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AZC_3126	COG2203	Gaf domain
AZC_3126	COG3706	GGDEF domain
AZC_3126	COG4251	negative regulation of phosphorylation
AZC_3126	COG5001	Diguanylate cyclase
AZC_3127	COG0556	nucleotide-excision repair
AZC_3131	COG0625	glutathione transferase activity
AZC_3136	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AZC_3139	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AZC_3144	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AZC_3145	COG0424	maF-like protein
AZC_3148	COG5328	Belongs to the UPF0262 family
AZC_3149	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AZC_3151	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AZC_3155	COG0840	transmembrane signaling receptor activity
AZC_3157	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZC_3160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZC_3161	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_3164	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_3166	COG3258	Cytochrome c
AZC_3167	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AZC_3168	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_3169	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_3174	COG1464	Belongs to the NlpA lipoprotein family
AZC_3176	COG0778	Nitroreductase
AZC_3179	COG1959	2 iron, 2 sulfur cluster binding
AZC_3181	COG1032	radical SAM domain protein
AZC_3187	COG1960	acyl-CoA dehydrogenase activity
AZC_3188	COG1024	Enoyl-CoA hydratase
AZC_3189	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_3192	COG0559	Belongs to the binding-protein-dependent transport system permease family
AZC_3194	COG1129	ABC transporter
AZC_3195	COG0410	ABC transporter
AZC_3198	COG1414	Transcriptional regulator
AZC_3199	COG1744	ABC transporter substrate-binding protein PnrA-like
AZC_3204	COG0154	amidase activity
AZC_3206	COG2274	protein secretion by the type I secretion system
AZC_3211	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_3212	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZC_3215	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AZC_3217	COG1215	transferase activity, transferring glycosyl groups
AZC_3226	COG5001	Diguanylate cyclase
AZC_3226	COG3300	MHYT domain
AZC_3232	COG0457	Tetratricopeptide repeat
AZC_3237	COG1120	ATPase activity
AZC_3240	COG4774	siderophore transport
AZC_3241	COG2311	Membrane
AZC_3248	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AZC_3249	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AZC_3250	COG2819	hydrolase of the alpha beta superfamily
AZC_3251	COG2091	lysine biosynthetic process via aminoadipic acid
AZC_3257	COG3093	addiction module antidote protein HigA
AZC_3261	COG0419	ATPase involved in DNA repair
AZC_3263	COG2963	transposase activity
AZC_3264	COG1674	ftsk spoiiie
AZC_3265	COG1309	transcriptional regulator
AZC_3271	COG1063	alcohol dehydrogenase
AZC_3274	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AZC_3275	COG2080	2 iron, 2 sulfur cluster binding
AZC_3278	COG2721	sulfolactate sulfo-lyase activity
AZC_3279	COG1063	alcohol dehydrogenase
AZC_3280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZC_3281	COG1126	abc transporter atp-binding protein
AZC_3282	COG0765	amino acid transport
AZC_3284	COG0246	Mannitol dehydrogenase
AZC_3285	COG1802	Transcriptional regulator
AZC_3286	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AZC_3287	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZC_3290	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AZC_3292	COG4191	Histidine kinase
AZC_3293	COG4566	intracellular signal transduction
AZC_3295	COG1914	H( )-stimulated, divalent metal cation uptake system
AZC_3296	COG2186	Transcriptional regulator
AZC_3298	COG0318	PFAM AMP-dependent synthetase and ligase
AZC_3299	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AZC_3302	COG1305	Transglutaminase-like
AZC_3303	COG2308	Evidence 4 Homologs of previously reported genes of
AZC_3303	COG2307	Protein conserved in bacteria
AZC_3306	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZC_3307	COG0653	protein targeting
AZC_3309	COG1132	(ABC) transporter
AZC_3311	COG2274	protein secretion by the type I secretion system
AZC_3312	COG0154	amidase activity
AZC_3313	COG5265	(ABC) transporter
AZC_3314	COG3034	peptidoglycan biosynthetic process
AZC_3315	COG0825	malonyl-CoA metabolic process
AZC_3318	COG1872	DUF167
AZC_3325	COG0438	transferase activity, transferring glycosyl groups
AZC_3325	COG1216	Glycosyl transferase, family 2
AZC_3327	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZC_3329	COG1846	Transcriptional regulator
AZC_3334	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_3335	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
AZC_3338	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AZC_3339	COG1802	Transcriptional regulator
AZC_3340	COG2721	sulfolactate sulfo-lyase activity
AZC_3342	COG1904	glucuronate isomerase
AZC_3345	COG1175	transmembrane transport
AZC_3347	COG0246	Mannitol dehydrogenase
AZC_3352	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AZC_3353	COG1301	dicarboxylic acid transport
AZC_3357	COG0583	DNA-binding transcription factor activity
AZC_3362	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AZC_3363	COG0489	protein tyrosine kinase activity
AZC_3364	COG1573	uracil-dna glycosylase
AZC_3365	COG0625	glutathione transferase activity
AZC_3371	COG0477	Major facilitator Superfamily
AZC_3372	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AZC_3374	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AZC_3375	COG0077	Prephenate dehydratase
AZC_3375	COG1605	Chorismate mutase
AZC_3377	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AZC_3379	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AZC_3380	COG3706	GGDEF domain
AZC_3381	COG0714	Associated with various cellular activities
AZC_3391	COG2188	Transcriptional regulator
AZC_3392	COG3624	Phosphonate C-P lyase system protein PhnG
AZC_3393	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AZC_3394	COG3626	phosphonate metabolism
AZC_3395	COG3627	carbon phosphorus lyase activity
AZC_3397	COG4107	phosphonate C-P lyase system protein PhnK
AZC_3398	COG4778	phosphonate C-P lyase system protein PhnL
AZC_3399	COG3454	Phosphonate metabolism
AZC_3400	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AZC_3409	COG0316	Belongs to the HesB IscA family
AZC_3411	COG1104	cysteine desulfurase activity
AZC_3412	COG5554	nitrogen fixation
AZC_3415	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AZC_3419	COG5554	nitrogen fixation
AZC_3423	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AZC_3435	COG2151	metal-sulfur cluster biosynthetic enzyme
AZC_3438	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AZC_3443	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
AZC_3447	COG2086	electron transfer activity
AZC_3448	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AZC_3449	COG0644	oxidoreductase
AZC_3450	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AZC_3451	COG5420	small protein containing a coiled-coil domain
AZC_3454	COG3383	formate dehydrogenase (NAD+) activity
AZC_3455	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AZC_3458	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AZC_3461	COG2267	carboxylic ester hydrolase activity
AZC_3463	COG1253	flavin adenine dinucleotide binding
AZC_3465	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AZC_3470	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AZC_3475	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AZC_3480	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AZC_3485	COG3220	belongs to the UPF0276 family
AZC_3488	COG3960	tartronate-semialdehyde synthase activity
AZC_3489	COG3622	Belongs to the hyi family
AZC_3490	COG2084	Dehydrogenase
AZC_3496	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AZC_3499	COG2857	Cytochrome c1
AZC_3499	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AZC_3500	COG2857	Cytochrome c1
AZC_3500	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AZC_3501	COG0723	plastoquinol--plastocyanin reductase activity
AZC_3502	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AZC_3503	COG0408	coproporphyrinogen oxidase activity
AZC_3505	COG0617	tRNA 3'-terminal CCA addition
AZC_3509	COG0714	Associated with various cellular activities
AZC_3516	COG2755	lipolytic protein G-D-S-L family
AZC_3516	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AZC_3517	COG1177	transmembrane transport
AZC_3518	COG1176	ABC-type spermidine putrescine transport system, permease component I
AZC_3519	COG3842	ATPase activity
AZC_3521	COG1819	glycosyl
AZC_3522	COG2814	Major facilitator Superfamily
AZC_3530	COG0129	dihydroxy-acid dehydratase activity
AZC_3531	COG3237	CsbD-like
AZC_3534	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_3537	COG1253	flavin adenine dinucleotide binding
AZC_3538	COG2066	Belongs to the glutaminase family
AZC_3539	COG5001	Diguanylate cyclase
AZC_3539	COG2203	Gaf domain
AZC_3539	COG3706	GGDEF domain
AZC_3539	COG4251	negative regulation of phosphorylation
AZC_3540	COG5001	Diguanylate cyclase
AZC_3540	COG3300	MHYT domain
AZC_3541	COG0352	thiamine-phosphate diphosphorylase activity
AZC_3543	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AZC_3545	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AZC_3552	COG2022	thiamine diphosphate biosynthetic process
AZC_3554	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZC_3554	COG2022	thiamine diphosphate biosynthetic process
AZC_3555	COG1846	Transcriptional regulator
AZC_3558	COG1960	acyl-CoA dehydrogenase activity
AZC_3564	COG4303	Ethanolamine ammonia lyase large subunit
AZC_3566	COG3706	GGDEF domain
AZC_3570	COG0582	viral genome integration into host DNA
AZC_3589	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AZC_3609	COG0316	Belongs to the HesB IscA family
AZC_3611	COG2151	metal-sulfur cluster biosynthetic enzyme
AZC_3612	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AZC_3613	COG0719	Fe-S assembly protein
AZC_3614	COG0396	ATPase activity
AZC_3615	COG0719	Fe-S assembly protein
AZC_3616	COG1104	cysteine desulfurase activity
AZC_3617	COG2945	thiolester hydrolase activity
AZC_3618	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AZC_3619	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AZC_3622	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AZC_3626	COG0860	N-Acetylmuramoyl-L-alanine amidase
AZC_3627	COG1530	ribonuclease E activity
AZC_3627	COG1530	ribonuclease E activity
AZC_3628	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AZC_3629	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AZC_3630	COG0363	glucosamine-6-phosphate deaminase activity
AZC_3631	COG0166	Belongs to the GPI family
AZC_3635	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AZC_3637	COG1802	Transcriptional regulator
AZC_3638	COG0505	Belongs to the CarA family
AZC_3642	COG0358	DNA primase activity
AZC_3643	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AZC_3646	COG0747	negative chemotaxis
AZC_3648	COG0174	glutamine synthetase
AZC_3650	COG0784	Response regulator, receiver
AZC_3651	COG0745	RESPONSE REGULATOR receiver
AZC_3654	COG1703	isobutyryl-CoA mutase activity
AZC_3655	COG3409	Peptidoglycan-binding domain 1 protein
AZC_3655	COG3773	Cell wall hydrolase
AZC_3656	COG0280	phosphate acetyltransferase
AZC_3656	COG0281	malic enzyme
AZC_3659	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AZC_3660	COG3300	MHYT domain
AZC_3660	COG5001	Diguanylate cyclase
AZC_3661	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AZC_3665	COG0248	Ppx GppA phosphatase
AZC_3666	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AZC_3667	COG1752	Esterase of the alpha-beta hydrolase superfamily
AZC_3668	COG0516	GMP reductase activity
AZC_3668	COG0517	IMP dehydrogenase activity
AZC_3675	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AZC_3684	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AZC_3691	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AZC_3692	COG2011	ABC-type metal ion transport system permease component
AZC_3693	COG1464	Belongs to the NlpA lipoprotein family
AZC_3697	COG0583	DNA-binding transcription factor activity
AZC_3698	COG1942	4-Oxalocrotonate Tautomerase
AZC_3705	COG0519	Catalyzes the synthesis of GMP from XMP
AZC_3705	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AZC_3708	COG0552	protein localization to endoplasmic reticulum
AZC_3709	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AZC_3710	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AZC_3712	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AZC_3716	COG0776	regulation of translation
AZC_3717	COG0616	signal peptide processing
AZC_3718	COG0840	transmembrane signaling receptor activity
AZC_3719	COG0539	negative regulation of cytoplasmic translation
AZC_3726	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AZC_3727	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AZC_3728	COG0427	acetyl-CoA hydrolase
AZC_3731	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AZC_3734	COG4208	sulfate ABC transporter
AZC_3739	COG2030	dehydratase
AZC_3742	COG3047	cAMP biosynthetic process
AZC_3744	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AZC_3749	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AZC_3750	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_3752	COG0129	dihydroxy-acid dehydratase activity
AZC_3753	COG3128	pkhd-type hydroxylase
AZC_3754	COG4774	siderophore transport
AZC_3755	COG1122	ATPase activity
AZC_3757	COG1268	BioY protein
AZC_3759	COG1271	oxidase subunit
AZC_3760	COG1294	oxidase, subunit
AZC_3763	COG1136	(ABC) transporter
AZC_3763	COG0577	efflux transmembrane transporter activity
AZC_3764	COG1136	(ABC) transporter
AZC_3768	COG0488	(ABC) transporter
AZC_3772	COG2072	flavoprotein involved in K transport
AZC_3774	COG0601	transmembrane transport
AZC_3777	COG0444	Belongs to the ABC transporter superfamily
AZC_3779	COG0747	negative chemotaxis
AZC_3789	COG4106	trans-aconitate 2-methyltransferase activity
AZC_3790	COG0488	(ABC) transporter
AZC_3792	COG0583	DNA-binding transcription factor activity
AZC_3794	COG4977	sequence-specific DNA binding
AZC_3808	COG4221	oxidoreductase activity
AZC_3809	COG0277	FAD linked oxidase domain protein
AZC_3810	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AZC_3812	COG0842	Transport permease protein
AZC_3813	COG1131	(ABC) transporter
AZC_3814	COG2192	nodulation
AZC_3815	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AZC_3816	COG1215	transferase activity, transferring glycosyl groups
AZC_3817	COG0726	polysaccharide deacetylase
AZC_3818	COG3153	acetyltransferase
AZC_3820	COG3328	transposase activity
AZC_3823	COG1858	cytochrome C peroxidase
AZC_3829	COG0741	lytic transglycosylase activity
AZC_3833	COG1192	Involved in chromosome partitioning
AZC_3836	COG5489	Protein of unknown function (DUF736)
AZC_3840	COG4691	Plasmid stability protein
AZC_3850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AZC_3851	COG3328	transposase activity
AZC_3856	COG3177	Filamentation induced by cAMP protein fic
AZC_3858	COG4962	Type ii secretion system protein e
AZC_3861	COG3451	type IV secretory pathway VirB4
AZC_3864	COG3846	protein secretion by the type IV secretion system
AZC_3865	COG3701	Conjugal transfer protein
AZC_3867	COG2948	multi-organism process
AZC_3870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZC_3871	COG0765	amino acid transport
AZC_3872	COG0765	amino acid transport
AZC_3873	COG0165	Argininosuccinate lyase
AZC_3875	COG1126	abc transporter atp-binding protein
AZC_3876	COG1760	l-serine dehydratase
AZC_3877	COG0583	DNA-binding transcription factor activity
AZC_3881	COG1476	TRANSCRIPTIONal
AZC_3882	COG4974	Belongs to the 'phage' integrase family
AZC_3888	COG0559	Belongs to the binding-protein-dependent transport system permease family
AZC_3896	COG1116	anion transmembrane transporter activity
AZC_3897	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AZC_3898	COG0300	oxidoreductase activity
AZC_3900	COG1335	isochorismatase
AZC_3903	COG0183	Belongs to the thiolase family
AZC_3905	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AZC_3907	COG1525	nuclease
AZC_3908	COG2205	protein histidine kinase activity
AZC_3908	COG2202	Pas domain
AZC_3911	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZC_3912	COG0728	peptidoglycan biosynthetic process
AZC_3913	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AZC_3914	COG3706	GGDEF domain
AZC_3915	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AZC_3918	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AZC_3919	COG2226	methyltransferase
AZC_3923	COG2205	protein histidine kinase activity
AZC_3925	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AZC_3926	COG1137	ATPase activity
AZC_3929	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AZC_3931	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AZC_3932	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AZC_3940	COG0024	Methionine aminopeptidase
AZC_3941	COG2099	Precorrin-6x reductase
AZC_3945	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
AZC_3946	COG1797	cobyrinic acid a,c-diamide synthase activity
AZC_3952	COG0228	four-way junction DNA binding
AZC_3953	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AZC_3954	COG0336	Belongs to the RNA methyltransferase TrmD family
AZC_3955	COG0335	large ribosomal subunit rRNA binding
AZC_3957	COG0435	Glutathione S-transferase
AZC_3960	COG0673	inositol 2-dehydrogenase activity
AZC_3963	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AZC_3966	COG0322	excinuclease ABC activity
AZC_3967	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AZC_3969	COG0314	molybdopterin synthase activity
AZC_3970	COG4251	negative regulation of phosphorylation
AZC_3970	COG3706	GGDEF domain
AZC_3970	COG2203	Gaf domain
AZC_3970	COG5001	Diguanylate cyclase
AZC_3971	COG3706	GGDEF domain
AZC_3971	COG2203	Gaf domain
AZC_3971	COG4251	negative regulation of phosphorylation
AZC_3971	COG5001	Diguanylate cyclase
AZC_3972	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AZC_3973	COG1846	Transcriptional regulator
AZC_3974	COG0745	RESPONSE REGULATOR receiver
AZC_3975	COG2205	protein histidine kinase activity
AZC_3977	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AZC_3982	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AZC_3986	COG0642	Histidine kinase
AZC_3990	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AZC_3993	COG1538	Outer membrane efflux protein
AZC_3995	COG1136	(ABC) transporter
AZC_3998	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AZC_3999	COG0671	phosphoesterase, PA-phosphatase related
AZC_4000	COG1671	Belongs to the UPF0178 family
AZC_4002	COG1695	Transcriptional regulator
AZC_4003	COG4974	Belongs to the 'phage' integrase family
AZC_4004	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AZC_4004	COG2755	lipolytic protein G-D-S-L family
AZC_4009	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AZC_4010	COG1280	lysine exporter protein (LysE YggA)
AZC_4011	COG0508	dehydrogenase complex catalyzes the overall conversion of
AZC_4014	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AZC_4015	COG0045	succinate-CoA ligase (ADP-forming) activity
AZC_4016	COG0039	L-malate dehydrogenase activity
AZC_4017	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AZC_4020	COG0717	Belongs to the dCTP deaminase family
AZC_4023	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AZC_4024	COG2967	ApaG domain
AZC_4025	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AZC_4026	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AZC_4027	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AZC_4028	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AZC_4032	COG0745	RESPONSE REGULATOR receiver
AZC_4033	COG0704	Plays a role in the regulation of phosphate uptake
AZC_4034	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AZC_4036	COG0573	inorganic phosphate transmembrane transporter activity
AZC_4041	COG3158	transport of potassium into the cell
AZC_4045	COG1278	Cold shock
AZC_4046	COG0778	Nitroreductase
AZC_4050	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AZC_4052	COG2353	YceI-like domain
AZC_4053	COG0706	membrane insertase activity
AZC_4054	COG0594	ribonuclease P activity
AZC_4055	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AZC_4056	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AZC_4056	COG4651	solute:proton antiporter activity
AZC_4057	COG0066	3-isopropylmalate dehydratase activity
AZC_4058	COG3038	cytochrome b561
AZC_4061	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AZC_4063	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AZC_4065	COG0745	RESPONSE REGULATOR receiver
AZC_4066	COG2205	protein histidine kinase activity
AZC_4068	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AZC_4068	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AZC_4069	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AZC_4070	COG3852	Histidine kinase
AZC_4072	COG1984	allophanate hydrolase subunit 2
AZC_4074	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AZC_4077	COG0559	Belongs to the binding-protein-dependent transport system permease family
AZC_4080	COG4336	lyase activity
AZC_4081	COG0583	DNA-binding transcription factor activity
AZC_4084	COG1660	Displays ATPase and GTPase activities
AZC_4088	COG2326	polyphosphate kinase activity
AZC_4089	COG0655	NAD(P)H dehydrogenase (quinone) activity
AZC_4090	COG0494	nUDIX hydrolase
AZC_4093	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AZC_4094	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AZC_4095	COG1607	acyl-coa hydrolase
AZC_4096	COG5001	Diguanylate cyclase
AZC_4096	COG4251	negative regulation of phosphorylation
AZC_4096	COG3706	GGDEF domain
AZC_4096	COG2203	Gaf domain
AZC_4098	COG2226	methyltransferase
AZC_4103	COG0411	ABC transporter
AZC_4107	COG2198	Histidine kinase
AZC_4107	COG0784	Response regulator, receiver
AZC_4107	COG2205	protein histidine kinase activity
AZC_4108	COG0745	RESPONSE REGULATOR receiver
AZC_4109	COG1595	DNA-templated transcription, initiation
AZC_4112	COG0488	(ABC) transporter
AZC_4114	COG0366	Alpha amylase catalytic
AZC_4115	COG0366	Alpha amylase catalytic
AZC_4116	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AZC_4117	COG1640	4-alpha-glucanotransferase
AZC_4121	COG0783	Belongs to the Dps family
AZC_4123	COG0583	DNA-binding transcription factor activity
AZC_4124	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AZC_4125	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AZC_4126	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AZC_4127	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AZC_4128	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AZC_4130	COG0765	amino acid transport
AZC_4131	COG0765	amino acid transport
AZC_4133	COG0793	Belongs to the peptidase S41A family
AZC_4135	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AZC_4136	COG0799	negative regulation of ribosome biogenesis
AZC_4137	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AZC_4138	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AZC_4141	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AZC_4146	COG3258	Cytochrome c
AZC_4147	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AZC_4148	COG0193	aminoacyl-tRNA hydrolase activity
AZC_4150	COG0012	GTP binding
AZC_4153	COG0667	Aldo Keto reductase
AZC_4155	COG0105	UTP biosynthetic process
AZC_4156	COG0861	Integral membrane protein TerC family
AZC_4157	COG0861	Integral membrane protein TerC family
AZC_4158	COG0243	molybdopterin cofactor binding
AZC_4160	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AZC_4161	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AZC_4162	COG0583	DNA-binding transcription factor activity
AZC_4165	COG2943	transferase activity, transferring hexosyl groups
AZC_4171	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AZC_4171	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AZC_4173	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_4174	COG0438	transferase activity, transferring glycosyl groups
AZC_4175	COG0445	tRNA wobble uridine modification
AZC_4176	COG0028	Belongs to the TPP enzyme family
AZC_4184	COG5487	UPF0391 membrane protein
AZC_4186	COG0039	L-malate dehydrogenase activity
AZC_4189	COG2368	4-hydroxyphenylacetate
AZC_4190	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AZC_4192	COG0438	transferase activity, transferring glycosyl groups
AZC_4194	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_4196	COG0739	heme binding
AZC_4202	COG1309	transcriptional regulator
AZC_4203	COG0024	Methionine aminopeptidase
AZC_4204	COG2003	Belongs to the UPF0758 family
AZC_4207	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AZC_4208	COG3842	ATPase activity
AZC_4210	COG1175	transmembrane transport
AZC_4211	COG0395	ABC-type sugar transport system, permease component
AZC_4212	COG2862	Uncharacterized protein family, UPF0114
AZC_4213	COG1366	Belongs to the anti-sigma-factor antagonist family
AZC_4223	COG2770	Histidine kinase
AZC_4223	COG2208	phosphoserine phosphatase activity
AZC_4224	COG2271	Major facilitator Superfamily
AZC_4225	COG0277	FAD linked oxidase domain protein
AZC_4226	COG0004	ammonium transporteR
AZC_4227	COG0347	Belongs to the P(II) protein family
AZC_4228	COG1946	Acyl-CoA thioesterase
AZC_4229	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AZC_4232	COG2835	tetraacyldisaccharide 4'-kinase activity
AZC_4233	COG0697	spore germination
AZC_4234	COG0124	histidyl-tRNA synthetase
AZC_4238	COG1489	DNA binding
AZC_4239	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AZC_4240	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AZC_4242	COG0612	Peptidase, M16
AZC_4243	COG0612	Peptidase, M16
AZC_4245	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AZC_4246	COG0509	glycine decarboxylation via glycine cleavage system
AZC_4248	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AZC_4249	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AZC_4250	COG0697	spore germination
AZC_4251	COG1620	l-lactate permease
AZC_4253	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AZC_4254	COG0564	pseudouridine synthase activity
AZC_4256	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AZC_4258	COG1196	nuclear chromosome segregation
AZC_4260	COG0356	it plays a direct role in the translocation of protons across the membrane
AZC_4261	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AZC_4262	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AZC_4263	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AZC_4265	COG0071	Belongs to the small heat shock protein (HSP20) family
AZC_4272	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AZC_4273	COG0330	HflC and HflK could
AZC_4275	COG3279	Response regulator of the LytR AlgR family
AZC_4277	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AZC_4281	COG0840	transmembrane signaling receptor activity
AZC_4282	COG1335	isochorismatase
AZC_4284	COG3145	DNA-N1-methyladenine dioxygenase activity
AZC_4286	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AZC_4287	COG1420	regulation of RNA biosynthetic process
AZC_4289	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AZC_4290	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AZC_4293	COG1937	Protein conserved in bacteria
AZC_4295	COG1040	competence protein
AZC_4297	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AZC_4300	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AZC_4301	COG0180	Tryptophanyl-tRNA synthetase
AZC_4302	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AZC_4304	COG0359	binds to the 23S rRNA
AZC_4305	COG0359	binds to the 23S rRNA
AZC_4307	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AZC_4308	COG0360	Binds together with S18 to 16S ribosomal RNA
AZC_4312	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AZC_4314	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AZC_4315	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AZC_4316	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AZC_4317	COG1561	YicC-like family, N-terminal region
AZC_4320	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AZC_4321	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AZC_4323	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AZC_4326	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
AZC_4328	COG1160	GTP binding
AZC_4331	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AZC_4339	COG2226	methyltransferase
AZC_4342	COG0606	chelatase, subunit chli
AZC_4344	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AZC_4346	COG2226	methyltransferase
AZC_4348	COG0189	ligase activity
AZC_4349	COG2226	methyltransferase
AZC_4350	COG0482	sulfurtransferase activity
AZC_4352	COG0326	Molecular chaperone. Has ATPase activity
AZC_4355	COG3260	NADH ubiquinone oxidoreductase 20
AZC_4356	COG0649	NAD binding
AZC_4357	COG0651	ATP synthesis coupled electron transport
AZC_4359	COG0650	Formate hydrogenlyase subunit 4
AZC_4360	COG0651	ATP synthesis coupled electron transport
AZC_4365	COG0745	RESPONSE REGULATOR receiver
AZC_4367	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AZC_4370	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_4371	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AZC_4376	COG1802	Transcriptional regulator
AZC_4377	COG0402	S-adenosylhomocysteine deaminase activity
AZC_4378	COG0667	Aldo Keto reductase
AZC_4379	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_4381	COG0252	asparaginase activity
AZC_4384	COG4771	TonB-dependent receptor
AZC_4385	COG4558	Periplasmic binding protein
AZC_4386	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AZC_4387	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AZC_4390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZC_4391	COG0842	Transport permease protein
AZC_4391	COG1129	ABC transporter
AZC_4392	COG0842	Transport permease protein
AZC_4393	COG0443	Heat shock 70 kDa protein
AZC_4395	COG1175	transmembrane transport
AZC_4396	COG0395	ABC-type sugar transport system, permease component
AZC_4398	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZC_4399	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AZC_4400	COG3665	Urea carboxylase-associated protein
AZC_4401	COG3665	Urea carboxylase-associated protein
AZC_4404	COG1609	Transcriptional regulator
AZC_4405	COG0765	amino acid transport
AZC_4406	COG0765	amino acid transport
AZC_4407	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZC_4408	COG1126	abc transporter atp-binding protein
AZC_4409	COG3734	2-keto-3-deoxy-galactonokinase
AZC_4410	COG0800	Aldolase
AZC_4412	COG0477	Major facilitator Superfamily
AZC_4421	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AZC_4427	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AZC_4430	COG0154	amidase activity
AZC_4433	COG4774	siderophore transport
AZC_4434	COG2309	aminopeptidase activity
AZC_4440	COG2972	Histidine kinase
AZC_4440	COG0840	transmembrane signaling receptor activity
AZC_4441	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZC_4442	COG0174	glutamine synthetase
AZC_4444	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AZC_4447	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AZC_4448	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AZC_4449	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AZC_4450	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AZC_4450	COG0072	phenylalanine-tRNA ligase activity
AZC_4452	COG0142	geranyltranstransferase activity
AZC_4453	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AZC_4454	COG2917	probably involved in intracellular septation
AZC_4455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AZC_4457	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AZC_4459	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AZC_4460	COG4133	protoheme IX ABC transporter activity
AZC_4461	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AZC_4464	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AZC_4464	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AZC_4465	COG1309	transcriptional regulator
AZC_4467	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZC_4471	COG0792	nuclease activity
AZC_4472	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AZC_4475	COG0210	DNA helicase
AZC_4478	COG2264	protein methyltransferase activity
AZC_4481	COG0277	FAD linked oxidase domain protein
AZC_4486	COG4974	Belongs to the 'phage' integrase family
AZC_4488	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AZC_4489	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AZC_4492	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AZC_4493	COG2890	protein-(glutamine-N5) methyltransferase activity
AZC_4496	COG1072	(Pantothenic acid kinase))
AZC_4497	COG0140	phosphoribosyl-ATP diphosphatase activity
AZC_4498	COG0107	imidazoleglycerol-phosphate synthase activity
AZC_4499	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AZC_4500	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AZC_4502	COG0131	Imidazoleglycerol-phosphate dehydratase
AZC_4505	COG2267	carboxylic ester hydrolase activity
AZC_4508	COG2902	Dehydrogenase
AZC_4514	COG0559	Belongs to the binding-protein-dependent transport system permease family
AZC_4517	COG1741	Belongs to the pirin family
AZC_4519	COG1309	transcriptional regulator
AZC_4521	COG1131	(ABC) transporter
AZC_4523	COG3278	Belongs to the heme-copper respiratory oxidase family
AZC_4526	COG2010	Cytochrome c
AZC_4529	COG2217	Heavy metal translocating P-type atpase
AZC_4532	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AZC_4533	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AZC_4535	COG0183	Belongs to the thiolase family
AZC_4539	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_4541	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AZC_4543	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AZC_4546	COG0275	rRNA processing
AZC_4547	COG2001	Belongs to the MraZ family
AZC_4549	COG3023	N-Acetylmuramoyl-L-alanine amidase
AZC_4553	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZC_4555	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AZC_4556	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AZC_4559	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AZC_4560	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AZC_4561	COG1181	Belongs to the D-alanine--D-alanine ligase family
AZC_4562	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AZC_4563	COG0849	cell division
AZC_4564	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AZC_4567	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AZC_4568	COG0497	DNA recombination
AZC_4569	COG1309	transcriptional regulator
AZC_4570	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_4571	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_4577	COG1028	Short-chain dehydrogenase reductase Sdr
AZC_4581	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AZC_4582	COG2353	YceI-like domain
AZC_4587	COG0559	Belongs to the binding-protein-dependent transport system permease family
AZC_4591	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AZC_4592	COG1024	Enoyl-CoA hydratase
AZC_4594	COG0519	Catalyzes the synthesis of GMP from XMP
AZC_4594	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AZC_4596	COG0564	pseudouridine synthase activity
AZC_4598	COG0583	DNA-binding transcription factor activity
AZC_4599	COG1737	Transcriptional regulator
AZC_4599	COG0837	glucose binding
AZC_4601	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AZC_4610	COG0037	tRNA processing
AZC_4610	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AZC_4611	COG2884	Cell division ATP-binding protein ftsE
AZC_4616	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AZC_4618	COG0287	Prephenate dehydrogenase
AZC_4619	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AZC_4623	COG2080	2 iron, 2 sulfur cluster binding
AZC_4623	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AZC_4624	COG2252	PERMEase
AZC_4625	COG0402	S-adenosylhomocysteine deaminase activity
AZC_4626	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AZC_4627	COG0438	transferase activity, transferring glycosyl groups
AZC_4629	COG1596	polysaccharide export
AZC_4638	COG0438	transferase activity, transferring glycosyl groups
AZC_4639	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AZC_4640	COG0167	dihydroorotate dehydrogenase activity
AZC_4641	COG1970	mechanosensitive ion channel activity
AZC_4642	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AZC_4644	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AZC_4645	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AZC_4652	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AZC_4653	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AZC_4654	COG4191	Histidine kinase
AZC_4655	COG4566	intracellular signal transduction
AZC_4656	COG4566	intracellular signal transduction
AZC_4657	COG0045	succinate-CoA ligase (ADP-forming) activity
AZC_4657	COG1042	CoA-binding domain protein
AZC_4657	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AZC_4658	COG5001	Diguanylate cyclase
AZC_4659	COG0019	diaminopimelate decarboxylase activity
AZC_4661	COG0778	Nitroreductase
AZC_4662	COG0165	Argininosuccinate lyase
AZC_4663	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AZC_4664	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZC_4665	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AZC_4666	COG2086	electron transfer activity
AZC_4667	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZC_4669	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AZC_4670	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AZC_4672	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AZC_4674	COG1968	undecaprenyl-diphosphatase activity
AZC_4676	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AZC_4682	COG2378	regulation of single-species biofilm formation
AZC_4684	COG2249	NAD(P)H dehydrogenase (quinone) activity
AZC_4685	COG0583	DNA-binding transcription factor activity
AZC_4686	COG0778	Nitroreductase
AZC_4689	COG2259	Doxx family
AZC_4696	COG0138	bifunctional purine biosynthesis protein purh
AZC_4701	COG0501	Belongs to the peptidase M48B family
AZC_4703	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AZC_4704	COG1214	PFAM Peptidase M22, glycoprotease
AZC_4707	COG1331	Highly conserved protein containing a thioredoxin domain
AZC_4708	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AZC_4709	COG0445	tRNA wobble uridine modification
AZC_4710	COG0357	Ribosomal RNA small subunit methyltransferase G
AZC_4711	COG1192	Involved in chromosome partitioning
AZC_4712	COG1475	DNA binding
AZC_4713	COG0306	phosphate transporter
AZC_4714	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AZC_4715	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AZC_4717	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III