locus-tag	class	description
J8L76_00020	COG0473	3-isopropylmalate dehydrogenase activity
J8L76_00025	COG0066	3-isopropylmalate dehydratase activity
J8L76_00035	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
J8L76_00040	COG2814	Major facilitator Superfamily
J8L76_00045	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
J8L76_00055	COG0308	aminopeptidase N
J8L76_00085	COG0440	acetolactate synthase activity
J8L76_00090	COG0028	Belongs to the TPP enzyme family
J8L76_00100	COG0318	PFAM AMP-dependent synthetase and ligase
J8L76_00110	COG1074	ATP-dependent DNA helicase activity
J8L76_00120	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
J8L76_00130	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
J8L76_00135	COG0254	rRNA binding
J8L76_00145	COG2010	Cytochrome c
J8L76_00150	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
J8L76_00155	COG0501	Belongs to the peptidase M48B family
J8L76_00165	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
J8L76_00190	COG0114	fumarate hydratase activity
J8L76_00195	COG1305	Transglutaminase-like
J8L76_00200	COG2308	Evidence 4 Homologs of previously reported genes of
J8L76_00215	COG3258	Cytochrome c
J8L76_00220	COG4566	intracellular signal transduction
J8L76_00240	COG2308	Evidence 4 Homologs of previously reported genes of
J8L76_00245	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
J8L76_00250	COG0494	nUDIX hydrolase
J8L76_00265	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J8L76_00265	COG0519	Catalyzes the synthesis of GMP from XMP
J8L76_00270	COG1666	GTP binding
J8L76_00275	COG3123	guanosine phosphorylase activity
J8L76_00285	COG0137	argininosuccinate synthase activity
J8L76_00290	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
J8L76_00295	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J8L76_00305	COG0268	Binds directly to 16S ribosomal RNA
J8L76_00315	COG1881	PFAM PEBP family protein
J8L76_00320	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
J8L76_00335	COG0205	6-phosphofructokinase activity
J8L76_00340	COG0563	adenylate kinase activity
J8L76_00345	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
J8L76_00350	COG2835	tetraacyldisaccharide 4'-kinase activity
J8L76_00355	COG1663	tetraacyldisaccharide 4'-kinase activity
J8L76_00360	COG0848	biopolymer transport protein
J8L76_00365	COG0811	peptide transport
J8L76_00370	COG1570	exodeoxyribonuclease VII activity
J8L76_00375	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
J8L76_00415	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
J8L76_00430	COG3161	chorismate lyase activity
J8L76_00450	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
J8L76_00460	COG0538	isocitrate dehydrogenase activity
J8L76_00500	COG0859	PFAM glycosyl transferase family 9
J8L76_00505	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
J8L76_00510	COG0022	dehydrogenase e1 component
J8L76_00530	COG1215	transferase activity, transferring glycosyl groups
J8L76_00540	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
J8L76_00545	COG0673	inositol 2-dehydrogenase activity
J8L76_00560	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J8L76_00565	COG0438	transferase activity, transferring glycosyl groups
J8L76_00565	COG1216	Glycosyl transferase, family 2
J8L76_00580	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J8L76_00585	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J8L76_00595	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
J8L76_00615	COG2257	FlhB HrpN YscU SpaS Family
J8L76_00620	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
J8L76_00625	COG1677	Flagellar hook-basal body complex protein FliE
J8L76_00635	COG4191	Histidine kinase
J8L76_00655	COG1157	protein secretion by the type III secretion system
J8L76_00665	COG3144	bacterial-type flagellum assembly
J8L76_00675	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J8L76_00680	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J8L76_00685	COG3190	flagellar
J8L76_00690	COG1338	Plays a role in the flagellum-specific transport system
J8L76_00695	COG1987	bacterial-type flagellum assembly
J8L76_00720	COG1705	Flagellar rod assembly protein muramidase FlgJ
J8L76_00720	COG3951	Flagellar rod assembly protein muramidase FlgJ
J8L76_00725	COG1706	bacterial-type flagellum-dependent cell motility
J8L76_00730	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
J8L76_00740	COG4787	bacterial-type flagellum-dependent cell motility
J8L76_00745	COG1749	Flagellar hook protein flgE
J8L76_00750	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
J8L76_00755	COG1558	bacterial-type flagellum-dependent cell motility
J8L76_00785	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J8L76_00790	COG1191	sigma factor activity
J8L76_00805	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
J8L76_00815	COG2198	Histidine kinase
J8L76_00815	COG0784	Response regulator, receiver
J8L76_00815	COG0643	Histidine kinase
J8L76_00820	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
J8L76_00830	COG0835	chemotaxis
J8L76_00830	COG0784	Response regulator, receiver
J8L76_00835	COG0835	chemotaxis
J8L76_00835	COG0784	Response regulator, receiver
J8L76_00840	COG2201	protein-glutamate methylesterase activity
J8L76_00845	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
J8L76_00855	COG0840	transmembrane signaling receptor activity
J8L76_00860	COG0835	chemotaxis
J8L76_00865	COG0643	Histidine kinase
J8L76_00865	COG2198	Histidine kinase
J8L76_00870	COG0745	RESPONSE REGULATOR receiver
J8L76_00920	COG1566	PFAM secretion protein HlyD family protein
J8L76_00925	COG2814	Major facilitator Superfamily
J8L76_00955	COG0583	DNA-binding transcription factor activity
J8L76_00965	COG2814	Major facilitator Superfamily
J8L76_00975	COG0456	acetyltransferase
J8L76_00995	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
J8L76_01000	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
J8L76_01010	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J8L76_01015	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
J8L76_01020	COG1674	ftsk spoiiie
J8L76_01025	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J8L76_01030	COG0492	ferredoxin-NADP+ reductase activity
J8L76_01035	COG1193	negative regulation of DNA recombination
J8L76_01040	COG0347	Belongs to the P(II) protein family
J8L76_01045	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
J8L76_01045	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J8L76_01050	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
J8L76_01080	COG1429	ligase activity, forming nitrogen-metal bonds
J8L76_01090	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
J8L76_01105	COG1304	FMN binding
J8L76_01110	COG4774	siderophore transport
J8L76_01115	COG3128	pkhd-type hydroxylase
J8L76_01135	COG0672	)-iron permease
J8L76_01150	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
J8L76_01160	COG2217	Heavy metal translocating P-type atpase
J8L76_01175	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J8L76_01180	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J8L76_01185	COG3945	hemerythrin HHE cation binding domain
J8L76_01205	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
J8L76_01225	COG2010	Cytochrome c
J8L76_01240	COG3278	Belongs to the heme-copper respiratory oxidase family
J8L76_01250	COG2217	Heavy metal translocating P-type atpase
J8L76_01255	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
J8L76_01260	COG0235	Class ii aldolase
J8L76_01270	COG2084	Dehydrogenase
J8L76_01275	COG2084	Dehydrogenase
J8L76_01290	COG0446	pyridine nucleotide-disulphide oxidoreductase
J8L76_01320	COG1490	D-aminoacyl-tRNA deacylase activity
J8L76_01325	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J8L76_01345	COG0280	phosphate acetyltransferase
J8L76_01345	COG0281	malic enzyme
J8L76_01350	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
J8L76_01355	COG0436	Aminotransferase
J8L76_01385	COG0267	Belongs to the bacterial ribosomal protein bL33 family
J8L76_01390	COG0227	Belongs to the bacterial ribosomal protein bL28 family
J8L76_01395	COG2003	Belongs to the UPF0758 family
J8L76_01400	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J8L76_01405	COG0756	dUTP diphosphatase activity
J8L76_01410	COG3264	Mechanosensitive ion channel
J8L76_01410	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
J8L76_01415	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J8L76_01415	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J8L76_01425	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J8L76_01435	COG0586	Pfam SNARE associated Golgi protein
J8L76_01440	COG0784	Response regulator, receiver
J8L76_01445	COG4251	negative regulation of phosphorylation
J8L76_01450	COG5001	Diguanylate cyclase
J8L76_01450	COG3300	MHYT domain
J8L76_01455	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
J8L76_01460	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
J8L76_01475	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
J8L76_01480	COG0628	permease
J8L76_01485	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
J8L76_01500	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J8L76_01520	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
J8L76_01525	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
J8L76_01530	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
J8L76_01545	COG1454	alcohol dehydrogenase
J8L76_01550	COG1012	belongs to the aldehyde dehydrogenase family
J8L76_01555	COG3284	Transcriptional regulator
J8L76_01580	COG4969	Belongs to the N-Me-Phe pilin family
J8L76_01590	COG1716	ATPase activity
J8L76_01600	COG0861	Integral membrane protein TerC family
J8L76_01605	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
J8L76_01610	COG0045	succinate-CoA ligase (ADP-forming) activity
J8L76_01620	COG0477	Major facilitator Superfamily
J8L76_01640	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
J8L76_01645	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J8L76_01650	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
J8L76_01665	COG0006	proline dipeptidase activity
J8L76_01670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J8L76_01695	COG0151	Belongs to the GarS family
J8L76_01700	COG3706	GGDEF domain
J8L76_01705	COG0408	coproporphyrinogen oxidase activity
J8L76_01720	COG2959	enzyme of heme biosynthesis
J8L76_01730	COG0181	hydroxymethylbilane synthase activity
J8L76_01735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J8L76_01765	COG0165	Argininosuccinate lyase
J8L76_01775	COG0004	ammonium transporteR
J8L76_01800	COG2890	protein-(glutamine-N5) methyltransferase activity
J8L76_01810	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
J8L76_01815	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
J8L76_01820	COG4208	sulfate ABC transporter
J8L76_01830	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
J8L76_01840	COG1858	cytochrome C peroxidase
J8L76_01850	COG0642	Histidine kinase
J8L76_01860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J8L76_01865	COG0842	Transport permease protein
J8L76_01865	COG1129	ABC transporter
J8L76_01870	COG0842	Transport permease protein
J8L76_01880	COG2205	protein histidine kinase activity
J8L76_01885	COG0745	RESPONSE REGULATOR receiver
J8L76_01890	COG3158	transport of potassium into the cell
J8L76_01900	COG2391	methyltransferase activity
J8L76_01905	COG0425	Belongs to the sulfur carrier protein TusA family
J8L76_01910	COG0459	protein refolding
J8L76_01915	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
J8L76_01920	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
J8L76_01945	COG0840	transmembrane signaling receptor activity
J8L76_01950	COG1475	DNA binding
J8L76_01955	COG0314	molybdopterin synthase activity
J8L76_01960	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
J8L76_01965	COG0303	'Molybdopterin
J8L76_01970	COG1763	Mo-molybdopterin cofactor biosynthetic process
J8L76_01975	COG2181	nitrate reductase activity
J8L76_01980	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
J8L76_01985	COG1140	nitrate reductase beta subunit
J8L76_01990	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
J8L76_01995	COG2223	nitrite transmembrane transporter activity
J8L76_02005	COG3850	Histidine kinase
J8L76_02010	COG2197	response regulator
J8L76_02015	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
J8L76_02020	COG0840	transmembrane signaling receptor activity
J8L76_02020	COG0840	transmembrane signaling receptor activity
J8L76_02030	COG0840	transmembrane signaling receptor activity
J8L76_02030	COG3290	protein histidine kinase activity
J8L76_02040	COG0330	HflC and HflK could
J8L76_02055	COG2197	response regulator
J8L76_02060	COG2201	protein-glutamate methylesterase activity
J8L76_02070	COG0745	RESPONSE REGULATOR receiver
J8L76_02080	COG2198	Histidine kinase
J8L76_02080	COG0643	Histidine kinase
J8L76_02090	COG0835	chemotaxis
J8L76_02100	COG2119	membrane
J8L76_02105	COG1230	cation diffusion facilitator family transporter
J8L76_02170	COG2204	response regulator
J8L76_02180	COG0583	DNA-binding transcription factor activity
J8L76_02190	COG3384	dioxygenase
J8L76_02200	COG3038	cytochrome b561
J8L76_02205	COG2353	YceI-like domain
J8L76_02210	COG2353	YceI-like domain
J8L76_02235	COG3162	membrane
J8L76_02240	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J8L76_02245	COG2271	Major facilitator Superfamily
J8L76_02250	COG2205	protein histidine kinase activity
J8L76_02255	COG0745	RESPONSE REGULATOR receiver
J8L76_02285	COG1489	DNA binding
J8L76_02325	COG2207	Transcriptional regulator
J8L76_02345	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
J8L76_02350	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
J8L76_02355	COG3610	response to peptide
J8L76_02375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J8L76_02390	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
J8L76_02395	COG1091	dTDP-4-dehydrorhamnose reductase activity
J8L76_02405	COG0840	transmembrane signaling receptor activity
J8L76_02410	COG0004	ammonium transporteR
J8L76_02415	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
J8L76_02425	COG0494	nUDIX hydrolase
J8L76_02430	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
J8L76_02445	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
J8L76_02450	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
J8L76_02455	COG0828	Belongs to the bacterial ribosomal protein bS21 family
J8L76_02505	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
J8L76_02515	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
J8L76_02540	COG0463	Glycosyl transferase, family 2
J8L76_02550	COG2201	protein-glutamate methylesterase activity
J8L76_02560	COG1741	Belongs to the pirin family
J8L76_02565	COG0583	DNA-binding transcription factor activity
J8L76_02570	COG0745	RESPONSE REGULATOR receiver
J8L76_02575	COG2205	protein histidine kinase activity
J8L76_02580	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
J8L76_02585	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
J8L76_02590	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
J8L76_02600	COG0477	Major facilitator Superfamily
J8L76_02620	COG2770	Histidine kinase
J8L76_02620	COG3437	response regulator, receiver
J8L76_02625	COG0210	DNA helicase
J8L76_02635	COG0495	leucyl-tRNA aminoacylation
J8L76_02645	COG1466	dna polymerase III delta subunit
J8L76_02655	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
J8L76_02670	COG4974	Belongs to the 'phage' integrase family
J8L76_02675	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
J8L76_02690	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
J8L76_02695	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
J8L76_02700	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
J8L76_02700	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
J8L76_02705	COG2204	response regulator
J8L76_02710	COG3852	Histidine kinase
J8L76_02720	COG0174	glutamine synthetase
J8L76_02730	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
J8L76_02740	COG3568	Endonuclease Exonuclease Phosphatase
J8L76_02745	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J8L76_02750	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J8L76_02760	COG0012	GTP binding
J8L76_02765	COG0193	aminoacyl-tRNA hydrolase activity
J8L76_02770	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
J8L76_02775	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J8L76_02790	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
J8L76_02795	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
J8L76_02805	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
J8L76_02810	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
J8L76_02815	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J8L76_02820	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
J8L76_02825	COG0742	ribosomal rna small subunit methyltransferase
J8L76_02830	COG0612	Peptidase, M16
J8L76_02835	COG0612	Peptidase, M16
J8L76_02845	COG2884	Cell division ATP-binding protein ftsE
J8L76_02850	COG2177	Part of the ABC transporter FtsEX involved in
J8L76_02865	COG0840	transmembrane signaling receptor activity
J8L76_02870	COG2198	Histidine kinase
J8L76_02870	COG0643	Histidine kinase
J8L76_02880	COG0745	RESPONSE REGULATOR receiver
J8L76_02905	COG4999	Histidine kinase
J8L76_02905	COG3850	Histidine kinase
J8L76_02905	COG3437	response regulator, receiver
J8L76_02905	COG2205	protein histidine kinase activity
J8L76_02920	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J8L76_02930	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J8L76_02935	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
J8L76_02940	COG0511	ligase activity, forming carbon-carbon bonds
J8L76_02945	COG0439	Biotin carboxylase
J8L76_02950	COG2264	protein methyltransferase activity
J8L76_02980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J8L76_03000	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
J8L76_03005	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J8L76_03005	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J8L76_03020	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J8L76_03035	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
J8L76_03040	COG0799	negative regulation of ribosome biogenesis
J8L76_03045	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
J8L76_03050	COG0424	maF-like protein
J8L76_03060	COG0826	peptidase U32
J8L76_03065	COG1530	ribonuclease E activity
J8L76_03070	COG0405	Gamma-glutamyltransferase
J8L76_03075	COG0412	Dienelactone hydrolase
J8L76_03085	COG0791	NLP P60 protein
J8L76_03095	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
J8L76_03100	COG2239	Acts as a magnesium transporter
J8L76_03105	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J8L76_03110	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
J8L76_03115	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
J8L76_03120	COG0557	exoribonuclease II activity
J8L76_03125	COG3150	esterase
J8L76_03135	COG1968	undecaprenyl-diphosphatase activity
J8L76_03145	COG1902	pentaerythritol trinitrate reductase activity
J8L76_03190	COG0778	Nitroreductase
J8L76_03195	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
J8L76_03200	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
J8L76_03205	COG3338	carbonate dehydratase activity
J8L76_03210	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
J8L76_03230	COG0859	PFAM glycosyl transferase family 9
J8L76_03250	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J8L76_03280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J8L76_03285	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
J8L76_03290	COG2755	lipolytic protein G-D-S-L family
J8L76_03290	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J8L76_03310	COG1215	transferase activity, transferring glycosyl groups
J8L76_03315	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J8L76_03320	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J8L76_03355	COG1216	Glycosyl transferase, family 2
J8L76_03360	COG0726	polysaccharide deacetylase
J8L76_03370	COG0438	transferase activity, transferring glycosyl groups
J8L76_03380	COG1132	(ABC) transporter
J8L76_03385	COG0438	transferase activity, transferring glycosyl groups
J8L76_03390	COG0859	PFAM glycosyl transferase family 9
J8L76_03400	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
J8L76_03405	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
J8L76_03415	COG1492	cobalamin metabolic process
J8L76_03440	COG0477	Major facilitator Superfamily
J8L76_03480	COG0738	Major facilitator superfamily
J8L76_03485	COG2165	general secretion pathway protein
J8L76_03495	COG0513	Belongs to the DEAD box helicase family
J8L76_03510	COG0488	(ABC) transporter
J8L76_03520	COG1944	ATP diphosphatase activity
J8L76_03525	COG2095	MarC family integral membrane protein
J8L76_03530	COG0583	DNA-binding transcription factor activity
J8L76_03535	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
J8L76_03540	COG0831	urea catabolic process
J8L76_03545	COG0832	Belongs to the urease beta subunit family
J8L76_03550	COG0804	urea catabolic process
J8L76_03555	COG1396	sequence-specific DNA binding
J8L76_03555	COG3800	Transcriptional regulator
J8L76_03560	COG1802	Transcriptional regulator
J8L76_03570	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J8L76_03580	COG4302	ethanolamine ammonia-lyase activity
J8L76_03595	COG2207	Transcriptional regulator
J8L76_03615	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J8L76_03635	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
J8L76_03640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J8L76_03645	COG4206	TonB-dependent receptor
J8L76_03655	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
J8L76_03665	COG0730	response to heat
J8L76_03670	COG0129	dihydroxy-acid dehydratase activity
J8L76_03675	COG0840	transmembrane signaling receptor activity
J8L76_03680	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
J8L76_03700	COG0433	COG0433 Predicted ATPase
J8L76_03705	COG0217	transcriptional regulatory protein
J8L76_03710	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
J8L76_03720	COG0632	four-way junction helicase activity
J8L76_03725	COG2255	four-way junction helicase activity
J8L76_03730	COG0824	Thioesterase
J8L76_03750	COG0823	Involved in the tonB-independent uptake of proteins
J8L76_03755	COG2885	chlorophyll binding
J8L76_03765	COG0602	queuosine metabolic process
J8L76_03775	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
J8L76_03790	COG0281	malic enzyme
J8L76_03790	COG0280	phosphate acetyltransferase
J8L76_03795	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
J8L76_03805	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
J8L76_03810	COG4191	Histidine kinase
J8L76_03820	COG0501	Belongs to the peptidase M48B family
J8L76_03830	COG0583	DNA-binding transcription factor activity
J8L76_03835	COG2204	response regulator
J8L76_03840	COG3550	peptidyl-serine autophosphorylation
J8L76_03855	COG2204	response regulator
J8L76_03865	COG0309	Hydrogenase expression formation protein (HypE)
J8L76_03880	COG0409	Hydrogenase expression formation protein
J8L76_03895	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
J8L76_03905	COG0375	protein maturation
J8L76_03910	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
J8L76_03920	COG4133	protoheme IX ABC transporter activity
J8L76_03925	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J8L76_03940	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
J8L76_03950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J8L76_03960	COG4235	cytochrome complex assembly
J8L76_03970	COG0084	hydrolase, TatD family'
J8L76_03975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J8L76_03980	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J8L76_03985	COG1758	RNA polymerase activity
J8L76_03990	COG0194	GDP metabolic process
J8L76_03995	COG1561	YicC-like family, N-terminal region
J8L76_04010	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
J8L76_04015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
J8L76_04020	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J8L76_04025	COG1515	deoxyribonuclease V activity
J8L76_04035	COG1881	PFAM PEBP family protein
J8L76_04040	COG3243	poly(R)-hydroxyalkanoic acid synthase
J8L76_04050	COG0183	Belongs to the thiolase family
J8L76_04065	COG1024	Enoyl-CoA hydratase
J8L76_04080	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J8L76_04085	COG1473	amidohydrolase
J8L76_04090	COG1660	Displays ATPase and GTPase activities
J8L76_04120	COG0741	lytic transglycosylase activity
J8L76_04135	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
J8L76_04140	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J8L76_04165	COG2022	thiamine diphosphate biosynthetic process
J8L76_04175	COG0220	tRNA (guanine-N7-)-methyltransferase activity
J8L76_04180	COG3154	lipid carrier protein
J8L76_04185	COG0826	peptidase U32
J8L76_04190	COG0826	peptidase U32
J8L76_04195	COG0730	response to heat
J8L76_04200	COG4221	oxidoreductase activity
J8L76_04205	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J8L76_04215	COG0018	arginyl-trna synthetase
J8L76_04220	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
J8L76_04225	COG2814	Major facilitator Superfamily
J8L76_04235	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J8L76_04240	COG4232	protein-disulfide reductase activity
J8L76_04260	COG3411	Ferredoxin
J8L76_04270	COG1131	(ABC) transporter
J8L76_04285	COG0010	Belongs to the arginase family
J8L76_04300	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
J8L76_04305	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J8L76_04310	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
J8L76_04315	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
J8L76_04320	COG1546	Belongs to the CinA family
J8L76_04325	COG2193	ferroxidase activity
J8L76_04335	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
J8L76_04350	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
J8L76_04355	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J8L76_04365	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
J8L76_04380	COG0037	tRNA processing
J8L76_04410	COG0625	glutathione transferase activity
J8L76_04425	COG3634	alkyl hydroperoxide reductase activity
J8L76_04440	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
J8L76_04505	COG0617	tRNA 3'-terminal CCA addition
J8L76_04520	COG0741	lytic transglycosylase activity
J8L76_04525	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
J8L76_04540	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
J8L76_04550	COG0432	Pfam Uncharacterised protein family UPF0047
J8L76_04570	COG0745	RESPONSE REGULATOR receiver
J8L76_04580	COG2226	methyltransferase
J8L76_04595	COG0355	proton-transporting ATP synthase activity, rotational mechanism
J8L76_04600	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
J8L76_04605	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
J8L76_04610	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
J8L76_04615	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
J8L76_04620	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
J8L76_04630	COG0356	it plays a direct role in the translocation of protons across the membrane
J8L76_04640	COG1475	DNA binding
J8L76_04645	COG1192	Involved in chromosome partitioning
J8L76_04650	COG0357	Ribosomal RNA small subunit methyltransferase G
J8L76_04655	COG0445	tRNA wobble uridine modification
J8L76_04670	COG4106	trans-aconitate 2-methyltransferase activity
J8L76_04675	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
J8L76_04685	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
J8L76_04690	COG0706	membrane insertase activity
J8L76_04695	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
J8L76_04700	COG0594	ribonuclease P activity
J8L76_04705	COG0230	Belongs to the bacterial ribosomal protein bL34 family
J8L76_04710	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
J8L76_04715	COG0592	DNA-directed DNA polymerase activity
J8L76_04750	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
J8L76_04780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J8L76_04810	COG1187	pseudouridine synthase activity
J8L76_04815	COG0583	DNA-binding transcription factor activity
J8L76_04820	COG1592	Rubrerythrin
J8L76_04840	COG2922	Belongs to the Smg family
J8L76_04845	COG0758	DNA mediated transformation
J8L76_04855	COG0242	peptide deformylase activity
J8L76_04860	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
J8L76_04875	COG2801	Transposase and inactivated derivatives
J8L76_04880	COG2801	Transposase and inactivated derivatives
J8L76_05000	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J8L76_05005	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J8L76_05005	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J8L76_05015	COG5000	phosphorelay sensor kinase activity
J8L76_05020	COG2204	response regulator
J8L76_05025	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
J8L76_05030	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J8L76_05035	COG2258	MOSC domain
J8L76_05040	COG1940	carbohydrate kinase activity
J8L76_05055	COG0288	reversible hydration of carbon dioxide
J8L76_05080	COG0812	UDP-N-acetylmuramate dehydrogenase activity
J8L76_05110	COG3876	Protein conserved in bacteria
J8L76_05115	COG2226	methyltransferase
J8L76_05120	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
J8L76_05140	COG3437	response regulator, receiver
J8L76_05145	COG2205	protein histidine kinase activity
J8L76_05145	COG3437	response regulator, receiver
J8L76_05145	COG3850	Histidine kinase
J8L76_05145	COG4999	Histidine kinase
J8L76_05150	COG2814	Major facilitator Superfamily
J8L76_05160	COG2960	long-chain fatty acid transporting porin activity
J8L76_05175	COG0004	ammonium transporteR
J8L76_05215	COG0174	glutamine synthetase
J8L76_05220	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
J8L76_05230	COG0069	glutamate synthase activity
J8L76_05235	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
J8L76_05240	COG0347	Belongs to the P(II) protein family
J8L76_05245	COG0004	ammonium transporteR
J8L76_05255	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
J8L76_05260	COG2863	cytochrome
J8L76_05265	COG3258	Cytochrome c
J8L76_05280	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
J8L76_05290	COG0788	formyltetrahydrofolate deformylase activity
J8L76_05300	COG0488	(ABC) transporter
J8L76_05325	COG0488	(ABC) transporter
J8L76_05340	COG0189	ligase activity
J8L76_05355	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J8L76_05360	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J8L76_05365	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J8L76_05370	COG2813	Specifically methylates the guanine in position
J8L76_05370	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J8L76_05375	COG2814	Major facilitator Superfamily
J8L76_05415	COG0708	Exodeoxyribonuclease III
J8L76_05420	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J8L76_05440	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J8L76_05450	COG0154	amidase activity
J8L76_05455	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J8L76_05460	COG1077	Cell shape determining protein MreB Mrl
J8L76_05465	COG1792	Involved in formation and maintenance of cell shape
J8L76_05475	COG0768	penicillin binding
J8L76_05480	COG0772	Belongs to the SEDS family
J8L76_05495	COG0347	Belongs to the P(II) protein family
J8L76_05515	COG1686	Belongs to the peptidase S11 family
J8L76_05520	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J8L76_05525	COG2921	Belongs to the UPF0250 family
J8L76_05530	COG0321	lipoyl(octanoyl) transferase activity
J8L76_05535	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
J8L76_05545	COG0583	DNA-binding transcription factor activity
J8L76_05550	COG1979	alcohol dehydrogenase
J8L76_05560	COG0667	Aldo Keto reductase
J8L76_05565	COG0656	L-ascorbic acid biosynthetic process
J8L76_05570	COG2814	Major facilitator Superfamily
J8L76_05650	COG0183	Belongs to the thiolase family
J8L76_05680	COG3453	Protein conserved in bacteria
J8L76_05680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J8L76_05685	COG2204	response regulator
J8L76_05700	COG0210	DNA helicase
J8L76_05710	COG3245	cytochrome
J8L76_05765	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J8L76_05795	COG3530	Putative quorum-sensing-regulated virulence factor
J8L76_05800	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
J8L76_05815	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
J8L76_05825	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
J8L76_05835	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
J8L76_05840	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
J8L76_05855	COG5420	small protein containing a coiled-coil domain
J8L76_05875	COG3585	molybdate ion transport
J8L76_05875	COG2005	Transcriptional regulator
J8L76_05940	COG3411	Ferredoxin
J8L76_05980	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
J8L76_05985	COG0352	thiamine-phosphate diphosphorylase activity
J8L76_05990	COG0351	phosphomethylpyrimidine kinase
J8L76_06015	COG2198	Histidine kinase
J8L76_06015	COG0784	Response regulator, receiver
J8L76_06015	COG0643	Histidine kinase
J8L76_06020	COG0415	Belongs to the DNA photolyase family
J8L76_06025	COG1678	Uncharacterized ACR, COG1678
J8L76_06030	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
J8L76_06035	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
J8L76_06040	COG0540	Belongs to the ATCase OTCase family
J8L76_06055	COG5000	phosphorelay sensor kinase activity
J8L76_06055	COG3279	Response regulator of the LytR AlgR family
J8L76_06060	COG1872	DUF167
J8L76_06065	COG0762	integral membrane protein
J8L76_06105	COG1981	membrane
J8L76_06115	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J8L76_06115	COG0543	2 iron, 2 sulfur cluster binding
J8L76_06120	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
J8L76_06155	COG1331	Highly conserved protein containing a thioredoxin domain
J8L76_06160	COG0583	DNA-binding transcription factor activity
J8L76_06180	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
J8L76_06185	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
J8L76_06195	COG0318	PFAM AMP-dependent synthetase and ligase
J8L76_06200	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
J8L76_06215	COG1247	-acetyltransferase
J8L76_06220	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
J8L76_06230	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
J8L76_06240	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J8L76_06250	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
J8L76_06255	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
J8L76_06260	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
J8L76_06265	COG0625	glutathione transferase activity
J8L76_06270	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
J8L76_06290	COG1965	Belongs to the frataxin family
J8L76_06295	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
J8L76_06330	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
J8L76_06335	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
J8L76_06340	COG0232	Belongs to the dGTPase family. Type 2 subfamily
J8L76_06345	COG0067	glutamate synthase
J8L76_06345	COG0069	glutamate synthase activity
J8L76_06345	COG0070	glutamate synthase
J8L76_06360	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
J8L76_06400	COG1703	isobutyryl-CoA mutase activity
J8L76_06400	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
J8L76_06400	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
J8L76_06420	COG1024	Enoyl-CoA hydratase
J8L76_06425	COG1802	Transcriptional regulator
J8L76_06430	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
J8L76_06430	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
J8L76_06435	COG1703	isobutyryl-CoA mutase activity
J8L76_06440	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J8L76_06445	COG4770	biotin carboxylase activity
J8L76_06455	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J8L76_06470	COG3210	domain, Protein
J8L76_06480	COG0277	FAD linked oxidase domain protein
J8L76_06500	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J8L76_06510	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J8L76_06525	COG0081	regulation of translation
J8L76_06530	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
J8L76_06535	COG0222	ribosome binding
J8L76_06540	COG0085	RNA polymerase activity
J8L76_06545	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
J8L76_06550	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
J8L76_06555	COG0049	tRNA binding
J8L76_06560	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J8L76_06565	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J8L76_06570	COG0051	transcription antitermination factor activity, RNA binding
J8L76_06575	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
J8L76_06580	COG0088	Forms part of the polypeptide exit tunnel
J8L76_06585	COG0089	rRNA binding
J8L76_06590	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
J8L76_06595	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
J8L76_06600	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
J8L76_06605	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
J8L76_06610	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
J8L76_06615	COG0255	Belongs to the universal ribosomal protein uL29 family
J8L76_06620	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
J8L76_06625	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
J8L76_06630	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
J8L76_06635	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
J8L76_06640	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
J8L76_06645	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
J8L76_06650	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
J8L76_06655	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
J8L76_06660	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
J8L76_06665	COG1841	ribosomal large subunit assembly
J8L76_06670	COG0200	Binds to the 23S rRNA
J8L76_06675	COG0201	protein transport
J8L76_06680	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
J8L76_06685	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J8L76_06690	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
J8L76_06695	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
J8L76_06700	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
J8L76_06705	COG0202	RNA polymerase activity
J8L76_06710	COG0203	ribosomal protein L17
J8L76_06715	COG5265	(ABC) transporter
J8L76_06730	COG1960	acyl-CoA dehydrogenase activity
J8L76_06735	COG0183	Belongs to the thiolase family
J8L76_06740	COG1250	3-hydroxyacyl-CoA dehydrogenase
J8L76_06740	COG1024	Enoyl-CoA hydratase
J8L76_06745	COG1607	acyl-coa hydrolase
J8L76_06750	COG2067	long-chain fatty acid transport protein
J8L76_06755	COG1250	3-hydroxyacyl-CoA dehydrogenase
J8L76_06755	COG1024	Enoyl-CoA hydratase
J8L76_06760	COG0183	Belongs to the thiolase family
J8L76_06800	COG1250	3-hydroxyacyl-CoA dehydrogenase
J8L76_06805	COG0840	transmembrane signaling receptor activity
J8L76_06810	COG0840	transmembrane signaling receptor activity
J8L76_06820	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
J8L76_06830	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
J8L76_06845	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J8L76_06850	COG1702	phosphate starvation-inducible protein PhoH
J8L76_06855	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
J8L76_06865	COG0815	Transfers the fatty acyl group on membrane lipoproteins
J8L76_06870	COG0752	glycyl-tRNA synthetase alpha subunit
J8L76_06875	COG0751	glycine-tRNA ligase activity
J8L76_06880	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
J8L76_06900	COG2201	protein-glutamate methylesterase activity
J8L76_06920	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J8L76_06945	COG0450	alkyl hydroperoxide reductase
J8L76_06955	COG1254	Belongs to the acylphosphatase family
J8L76_06960	COG0659	secondary active sulfate transmembrane transporter activity
J8L76_06965	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J8L76_06965	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J8L76_06970	COG0489	protein tyrosine kinase activity
J8L76_06975	COG0717	Belongs to the dCTP deaminase family
J8L76_06990	COG0166	Belongs to the GPI family
J8L76_06995	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
J8L76_07005	COG0521	Mo-molybdopterin cofactor biosynthetic process
J8L76_07010	COG3028	Belongs to the UPF0307 family
J8L76_07015	COG0312	modulator of DNA gyrase
J8L76_07020	COG0406	alpha-ribazole phosphatase activity
J8L76_07025	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J8L76_07030	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
J8L76_07035	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J8L76_07035	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J8L76_07040	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J8L76_07050	COG0793	Belongs to the peptidase S41A family
J8L76_07055	COG4942	peptidase
J8L76_07065	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J8L76_07075	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
J8L76_07085	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
J8L76_07090	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
J8L76_07095	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J8L76_07100	COG1459	type II secretion system
J8L76_07110	COG2165	general secretion pathway protein
J8L76_07180	COG3267	Type II secretory pathway component ExeA
J8L76_07180	COG3409	Peptidoglycan-binding domain 1 protein
J8L76_07190	COG1040	competence protein
J8L76_07195	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
J8L76_07200	COG2226	methyltransferase
J8L76_07210	COG0218	Necessary for normal cell division and for the maintenance of normal septation
J8L76_07225	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J8L76_07255	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
J8L76_07270	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
J8L76_07285	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J8L76_07290	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J8L76_07295	COG0741	lytic transglycosylase activity
J8L76_07300	COG0442	prolyl-tRNA aminoacylation
J8L76_07305	COG0494	nUDIX hydrolase
J8L76_07320	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
J8L76_07325	COG1765	OsmC-like protein
J8L76_07330	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
J8L76_07335	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
J8L76_07350	COG0316	Belongs to the HesB IscA family
J8L76_07400	COG1643	Atp-dependent helicase
J8L76_07410	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J8L76_07420	COG0284	orotidine-5'-phosphate decarboxylase activity
J8L76_07430	COG1024	Enoyl-CoA hydratase
J8L76_07435	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
J8L76_07445	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
J8L76_07500	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J8L76_07510	COG1450	Type ii and iii secretion system protein
J8L76_07515	COG1127	ABC transporter
J8L76_07520	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
J8L76_07525	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J8L76_07530	COG2853	Lipoprotein
J8L76_07545	COG1131	(ABC) transporter
J8L76_07550	COG0842	Transport permease protein
J8L76_07555	COG0271	Belongs to the BolA IbaG family
J8L76_07560	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J8L76_07565	COG2823	Periplasmic or secreted lipoprotein
J8L76_07570	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
J8L76_07580	COG0792	nuclease activity
J8L76_07585	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
J8L76_07590	COG0418	dihydroorotase activity
J8L76_07610	COG2001	Belongs to the MraZ family
J8L76_07615	COG0275	rRNA processing
J8L76_07620	COG3116	cell division
J8L76_07630	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J8L76_07635	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J8L76_07640	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J8L76_07645	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
J8L76_07650	COG0772	Belongs to the SEDS family
J8L76_07655	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J8L76_07660	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J8L76_07665	COG1181	Belongs to the D-alanine--D-alanine ligase family
J8L76_07670	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
J8L76_07680	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J8L76_07685	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
J8L76_07700	COG0739	heme binding
J8L76_07705	COG0653	protein targeting
J8L76_07710	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
J8L76_07725	COG2226	methyltransferase
J8L76_07730	COG2967	ApaG domain
J8L76_07735	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J8L76_07740	COG0546	phosphoglycolate phosphatase activity
J8L76_07755	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J8L76_07760	COG0134	indole-3-glycerol-phosphate synthase activity
J8L76_07770	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
J8L76_07775	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
J8L76_07780	COG0211	Belongs to the bacterial ribosomal protein bL27 family
J8L76_07785	COG0261	This protein binds to 23S rRNA in the presence of protein L20
J8L76_07790	COG0142	geranyltranstransferase activity
J8L76_07810	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J8L76_07820	COG0243	molybdopterin cofactor binding
J8L76_07835	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J8L76_07845	COG1116	anion transmembrane transporter activity
J8L76_07850	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
J8L76_07860	COG0745	RESPONSE REGULATOR receiver
J8L76_07865	COG2205	protein histidine kinase activity
J8L76_07880	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
J8L76_07885	COG3706	GGDEF domain
J8L76_07890	COG5002	protein histidine kinase activity
J8L76_07890	COG2176	DNA-directed DNA polymerase activity
J8L76_07895	COG0840	transmembrane signaling receptor activity
J8L76_07900	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J8L76_07915	COG0708	Exodeoxyribonuclease III
J8L76_07925	COG0339	signal peptide processing
J8L76_07935	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
J8L76_07940	COG2226	methyltransferase
J8L76_07970	COG0598	Magnesium transport protein CorA
J8L76_07975	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J8L76_07995	COG1187	pseudouridine synthase activity
J8L76_08005	COG0513	Belongs to the DEAD box helicase family
J8L76_08010	COG2030	dehydratase
J8L76_08020	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J8L76_08040	COG0778	Nitroreductase
J8L76_08045	COG0469	pyruvate kinase activity
J8L76_08050	COG2833	Protein of unknown function (DUF455)
J8L76_08070	COG1294	oxidase, subunit
J8L76_08085	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
J8L76_08090	COG0126	phosphoglycerate kinase activity
J8L76_08095	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J8L76_08130	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J8L76_08135	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J8L76_08140	COG3954	Phosphoribulokinase
J8L76_08145	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
J8L76_08155	COG0483	inositol monophosphate 1-phosphatase activity
J8L76_08170	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J8L76_08180	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
J8L76_08180	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J8L76_08190	COG1253	flavin adenine dinucleotide binding
J8L76_08200	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
J8L76_08210	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
J8L76_08220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J8L76_08225	COG0508	dehydrogenase complex catalyzes the overall conversion of
J8L76_08230	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
J8L76_08240	COG4566	intracellular signal transduction
J8L76_08245	COG0840	transmembrane signaling receptor activity
J8L76_08250	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
J8L76_08255	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
J8L76_08260	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
J8L76_08265	COG0009	L-threonylcarbamoyladenylate synthase
J8L76_08285	COG2814	Major facilitator Superfamily
J8L76_08290	COG0629	single-stranded DNA binding
J8L76_08305	COG3158	transport of potassium into the cell
J8L76_08315	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J8L76_08320	COG3706	GGDEF domain
J8L76_08335	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
J8L76_08340	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J8L76_08345	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J8L76_08350	COG0131	Imidazoleglycerol-phosphate dehydratase
J8L76_08355	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
J8L76_08360	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
J8L76_08365	COG0107	imidazoleglycerol-phosphate synthase activity
J8L76_08370	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
J8L76_08375	COG0140	phosphoribosyl-ATP diphosphatase activity
J8L76_08385	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J8L76_08390	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J8L76_08400	COG0121	glutamine amidotransferase
J8L76_08405	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J8L76_08410	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J8L76_08420	COG3647	Membrane
J8L76_08425	COG2203	Gaf domain
J8L76_08425	COG3706	GGDEF domain
J8L76_08425	COG4251	negative regulation of phosphorylation
J8L76_08425	COG5001	Diguanylate cyclase
J8L76_08435	COG2201	protein-glutamate methylesterase activity
J8L76_08445	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
J8L76_08450	COG0835	chemotaxis
J8L76_08455	COG0840	transmembrane signaling receptor activity
J8L76_08460	COG0643	Histidine kinase
J8L76_08460	COG2198	Histidine kinase
J8L76_08475	COG0745	RESPONSE REGULATOR receiver
J8L76_08480	COG0501	Belongs to the peptidase M48B family
J8L76_08490	COG1253	flavin adenine dinucleotide binding
J8L76_08495	COG1346	cytolysis
J8L76_08500	COG1380	Effector of murein hydrolase LrgA
J8L76_08520	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J8L76_08525	COG0840	transmembrane signaling receptor activity
J8L76_08550	COG0583	DNA-binding transcription factor activity
J8L76_08555	COG1902	pentaerythritol trinitrate reductase activity
J8L76_08560	COG0778	Nitroreductase
J8L76_08565	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
J8L76_08570	COG0730	response to heat
J8L76_08580	COG0583	DNA-binding transcription factor activity
J8L76_08590	COG4651	solute:proton antiporter activity
J8L76_08590	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J8L76_08600	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J8L76_08605	COG0542	response to heat
J8L76_08610	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
J8L76_08615	COG1278	Cold shock
J8L76_08620	COG0315	cyclic pyranopterin monophosphate synthase activity
J8L76_08625	COG4783	chaperone-mediated protein folding
J8L76_08630	COG0425	Belongs to the sulfur carrier protein TusA family
J8L76_08635	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J8L76_08640	COG0525	valine-tRNA ligase activity
J8L76_08655	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
J8L76_08660	COG0795	lipopolysaccharide-transporting ATPase activity
J8L76_08690	COG0028	Belongs to the TPP enzyme family
J8L76_08695	COG0440	acetolactate synthase activity
J8L76_08700	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
J8L76_08705	COG0688	phosphatidylethanolamine metabolic process
J8L76_08710	COG1183	phosphatidylcholine synthase activity
J8L76_08740	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J8L76_08750	COG1295	ribonuclease BN
J8L76_08760	COG0228	four-way junction DNA binding
J8L76_08765	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
J8L76_08770	COG0336	Belongs to the RNA methyltransferase TrmD family
J8L76_08775	COG0335	large ribosomal subunit rRNA binding
J8L76_08780	COG1469	GTP cyclohydrolase I activity
J8L76_08785	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
J8L76_08790	COG0142	geranyltranstransferase activity
J8L76_08795	COG1722	exodeoxyribonuclease VII activity
J8L76_08825	COG0802	atpase or kinase
J8L76_08830	COG0860	N-Acetylmuramoyl-L-alanine amidase
J8L76_08835	COG0196	riboflavin kinase activity
J8L76_08840	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
J8L76_08845	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
J8L76_08850	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
J8L76_08855	COG1047	Peptidyl-prolyl cis-trans
J8L76_08860	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
J8L76_08915	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
J8L76_08925	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J8L76_08930	COG0312	modulator of DNA gyrase
J8L76_08940	COG3437	response regulator, receiver
J8L76_08945	COG2205	protein histidine kinase activity
J8L76_08945	COG3437	response regulator, receiver
J8L76_08945	COG3850	Histidine kinase
J8L76_08945	COG4999	Histidine kinase
J8L76_08960	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J8L76_08990	COG0427	acetyl-CoA hydrolase
J8L76_09025	COG2096	Adenosyltransferase
J8L76_09030	COG3622	Belongs to the hyi family
J8L76_09065	COG0513	Belongs to the DEAD box helicase family
J8L76_09080	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J8L76_09085	COG0039	L-malate dehydrogenase activity
J8L76_09090	COG0584	glycerophosphoryl diester phosphodiesterase
J8L76_09105	COG0477	Major facilitator Superfamily
J8L76_09110	COG0667	Aldo Keto reductase
J8L76_09115	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
J8L76_09140	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
J8L76_09145	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
J8L76_09155	COG0429	hydrolase of the alpha beta-hydrolase fold
J8L76_09190	COG0482	sulfurtransferase activity
J8L76_09200	COG0277	FAD linked oxidase domain protein
J8L76_09205	COG4221	oxidoreductase activity
J8L76_09210	COG0625	glutathione transferase activity
J8L76_09225	COG3909	cytochrome
J8L76_09235	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J8L76_09240	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J8L76_09245	COG1862	Preprotein translocase
J8L76_09250	COG0343	queuine tRNA-ribosyltransferase activity
J8L76_09255	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
J8L76_09320	COG1876	peptidase activity
J8L76_09415	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
J8L76_09420	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
J8L76_09425	COG0723	plastoquinol--plastocyanin reductase activity
J8L76_09430	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
J8L76_09435	COG2857	Cytochrome c1
J8L76_09440	COG0625	glutathione transferase activity
J8L76_09445	COG2969	positive regulation of protein catabolic process
J8L76_09450	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J8L76_09465	COG0438	transferase activity, transferring glycosyl groups
J8L76_09475	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
J8L76_09480	COG1942	4-Oxalocrotonate Tautomerase
J8L76_09510	COG5002	protein histidine kinase activity
J8L76_09510	COG2205	protein histidine kinase activity
J8L76_09510	COG0784	Response regulator, receiver
J8L76_09515	COG2205	protein histidine kinase activity
J8L76_09515	COG0784	Response regulator, receiver
J8L76_09520	COG3437	response regulator, receiver
J8L76_09520	COG2205	protein histidine kinase activity
J8L76_09520	COG3850	Histidine kinase
J8L76_09520	COG4999	Histidine kinase
J8L76_09540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J8L76_09550	COG1966	Carbon starvation protein
J8L76_09570	COG1960	acyl-CoA dehydrogenase activity
J8L76_09590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J8L76_09595	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J8L76_09600	COG1538	Outer membrane efflux protein
J8L76_09605	COG3781	membrane
J8L76_09615	COG0583	DNA-binding transcription factor activity
J8L76_09620	COG0402	S-adenosylhomocysteine deaminase activity
J8L76_09635	COG0446	pyridine nucleotide-disulphide oxidoreductase
J8L76_09655	COG2010	Cytochrome c
J8L76_09675	COG0714	Associated with various cellular activities
J8L76_09700	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J8L76_09700	COG1648	precorrin-2 dehydrogenase activity
J8L76_09710	COG4654	Cytochrome c, class I
J8L76_09740	COG0535	radical SAM domain protein
J8L76_09745	COG2010	Cytochrome c
J8L76_09750	COG1959	2 iron, 2 sulfur cluster binding
J8L76_09780	COG0488	(ABC) transporter
J8L76_09790	COG1704	LemA family
J8L76_09800	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J8L76_09820	COG1832	CoA-binding protein
J8L76_09825	COG1024	Enoyl-CoA hydratase
J8L76_09830	COG0626	cystathionine gamma-synthase activity
J8L76_09855	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
J8L76_09865	COG1999	signal sequence binding
J8L76_09875	COG1116	anion transmembrane transporter activity
J8L76_09885	COG4943	cyclic-guanylate-specific phosphodiesterase activity
J8L76_09920	COG2895	sulfate adenylyltransferase (ATP) activity
J8L76_09925	COG0175	sulfate reduction
J8L76_09930	COG0175	sulfate reduction
J8L76_09940	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J8L76_09945	COG0730	response to heat
J8L76_09950	COG0583	DNA-binding transcription factor activity
J8L76_09960	COG0360	Binds together with S18 to 16S ribosomal RNA
J8L76_09970	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
J8L76_09975	COG0359	binds to the 23S rRNA
J8L76_10000	COG0305	Participates in initiation and elongation during chromosome replication
J8L76_10010	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
J8L76_10015	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J8L76_10025	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J8L76_10035	COG0726	polysaccharide deacetylase
J8L76_10045	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J8L76_10045	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
J8L76_10055	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J8L76_10060	COG2076	Multidrug Resistance protein
J8L76_10075	COG0436	Aminotransferase
J8L76_10080	COG0436	Aminotransferase
J8L76_10100	COG2890	protein-(glutamine-N5) methyltransferase activity
J8L76_10110	COG0069	glutamate synthase activity
J8L76_10120	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
J8L76_10125	COG4772	TonB-dependent receptor
J8L76_10135	COG5002	protein histidine kinase activity
J8L76_10135	COG3447	MASE1 domain protein
J8L76_10135	COG5001	Diguanylate cyclase
J8L76_10140	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J8L76_10140	COG0047	phosphoribosylformylglycinamidine synthase activity
J8L76_10150	COG2200	EAL domain
J8L76_10155	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J8L76_10165	COG2350	Protein conserved in bacteria
J8L76_10170	COG2917	probably involved in intracellular septation
J8L76_10175	COG0784	Response regulator, receiver
J8L76_10175	COG5002	protein histidine kinase activity
J8L76_10175	COG2205	protein histidine kinase activity
J8L76_10180	COG2995	paraquat-inducible protein a
J8L76_10185	COG2995	paraquat-inducible protein a
J8L76_10190	COG3008	intermembrane lipid transfer
J8L76_10210	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
J8L76_10215	COG2226	methyltransferase
J8L76_10220	COG2267	carboxylic ester hydrolase activity
J8L76_10225	COG0156	8-amino-7-oxononanoate synthase activity
J8L76_10245	COG3022	response to hydroperoxide
J8L76_10255	COG2084	Dehydrogenase
J8L76_10260	COG2050	protein possibly involved in aromatic compounds catabolism
J8L76_10270	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
J8L76_10285	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J8L76_10290	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
J8L76_10300	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
J8L76_10305	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
J8L76_10310	COG3383	formate dehydrogenase (NAD+) activity
J8L76_10315	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
J8L76_10320	COG3259	Nickel-dependent hydrogenase
J8L76_10335	COG0306	phosphate transporter
J8L76_10350	COG0596	Alpha beta hydrolase
J8L76_10370	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
J8L76_10375	COG0437	4 iron, 4 sulfur cluster binding
J8L76_10380	COG5557	Pfam Polysulphide reductase, NrfD
J8L76_10385	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
J8L76_10390	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
J8L76_10415	COG0326	Molecular chaperone. Has ATPase activity
J8L76_10420	COG0477	Major facilitator Superfamily
J8L76_10430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J8L76_10465	COG0848	biopolymer transport protein
J8L76_10470	COG0811	peptide transport
J8L76_10490	COG1250	3-hydroxyacyl-CoA dehydrogenase
J8L76_10500	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
J8L76_10505	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J8L76_10525	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
J8L76_10550	COG0587	DNA-directed DNA polymerase activity
J8L76_10655	COG2318	DinB family
J8L76_10665	COG0504	CTP synthase activity
J8L76_10670	COG2877	3-deoxy-8-phosphooctulonate synthase activity
J8L76_10675	COG0148	phosphopyruvate hydratase activity
J8L76_10680	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
J8L76_10690	COG2814	Major facilitator Superfamily
J8L76_10715	COG2205	protein histidine kinase activity
J8L76_10730	COG0528	UMP kinase activity
J8L76_10735	COG0528	UMP kinase activity
J8L76_10750	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
J8L76_10765	COG0328	RNA-DNA hybrid ribonuclease activity
J8L76_10770	COG2226	methyltransferase
J8L76_10775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J8L76_10780	COG2201	protein-glutamate methylesterase activity
J8L76_10785	COG5001	Diguanylate cyclase
J8L76_10785	COG4251	negative regulation of phosphorylation
J8L76_10785	COG3706	GGDEF domain
J8L76_10785	COG2203	Gaf domain
J8L76_10810	COG0515	serine threonine protein kinase
J8L76_10810	COG2815	serine threonine protein kinase
J8L76_10820	COG0564	pseudouridine synthase activity
J8L76_10840	COG3243	poly(R)-hydroxyalkanoic acid synthase
J8L76_10855	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J8L76_10860	COG1752	Esterase of the alpha-beta hydrolase superfamily
J8L76_10865	COG0277	FAD linked oxidase domain protein
J8L76_10880	COG1393	Belongs to the ArsC family
J8L76_10890	COG2183	response to ionizing radiation
J8L76_10900	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
J8L76_10920	COG0798	PFAM Bile acid sodium symporter
J8L76_10925	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J8L76_10945	COG2132	Multicopper oxidase
J8L76_10950	COG5002	protein histidine kinase activity
J8L76_10970	COG2195	Cleaves the N-terminal amino acid of tripeptides
J8L76_11000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J8L76_11010	COG1120	ATPase activity
J8L76_11015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J8L76_11020	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J8L76_11040	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
J8L76_11045	COG2329	Antibiotic biosynthesis monooxygenase
J8L76_11050	COG4681	YaeQ
J8L76_11060	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
J8L76_11070	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J8L76_11080	COG0840	transmembrane signaling receptor activity
J8L76_11105	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J8L76_11110	COG0443	Heat shock 70 kDa protein
J8L76_11115	COG1346	cytolysis
J8L76_11125	COG0583	DNA-binding transcription factor activity
J8L76_11130	COG2900	Belongs to the SlyX family
J8L76_11140	COG0826	peptidase U32
J8L76_11150	COG1902	pentaerythritol trinitrate reductase activity
J8L76_11155	COG0348	domain, Protein
J8L76_11160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J8L76_11170	COG1132	(ABC) transporter
J8L76_11175	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J8L76_11175	COG0189	ligase activity
J8L76_11180	COG0189	ligase activity
J8L76_11180	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J8L76_11190	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
J8L76_11210	COG0583	DNA-binding transcription factor activity
J8L76_11215	COG2199	diguanylate cyclase activity
J8L76_11215	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
J8L76_11225	COG0488	(ABC) transporter
J8L76_11230	COG2204	response regulator
J8L76_11240	COG1294	oxidase, subunit
J8L76_11245	COG0723	plastoquinol--plastocyanin reductase activity
J8L76_11260	COG0386	Belongs to the glutathione peroxidase family
J8L76_11305	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
J8L76_11305	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
J8L76_11310	COG0509	glycine decarboxylation via glycine cleavage system
J8L76_11315	COG0404	The glycine cleavage system catalyzes the degradation of glycine
J8L76_11330	COG0613	PHP domain protein
J8L76_11335	COG0009	L-threonylcarbamoyladenylate synthase
J8L76_11340	COG1994	Peptidase M50
J8L76_11345	COG0180	Tryptophanyl-tRNA synthetase
J8L76_11355	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
J8L76_11360	COG1187	pseudouridine synthase activity
J8L76_11365	COG0779	Required for maturation of 30S ribosomal subunits
J8L76_11370	COG0195	Participates in both transcription termination and antitermination
J8L76_11370	COG2251	uridine kinase activity
J8L76_11375	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
J8L76_11380	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
J8L76_11385	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
J8L76_11390	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
J8L76_11395	COG1185	polyribonucleotide nucleotidyltransferase activity
J8L76_11400	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J8L76_11430	COG0577	efflux transmembrane transporter activity
J8L76_11430	COG1136	(ABC) transporter
J8L76_11435	COG0778	Nitroreductase
J8L76_11450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J8L76_11455	COG1120	ATPase activity
J8L76_11470	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J8L76_11500	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
J8L76_11590	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J8L76_11600	COG2171	N-acyltransferase activity
J8L76_11605	COG0436	Aminotransferase
J8L76_11615	COG3318	Belongs to the UPF0149 family
J8L76_11615	COG3012	SEC-C Motif Domain Protein
J8L76_11630	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
J8L76_11640	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
J8L76_11650	COG0242	peptide deformylase activity
J8L76_11655	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
J8L76_11660	COG0024	Methionine aminopeptidase
J8L76_11665	COG0052	Belongs to the universal ribosomal protein uS2 family
J8L76_11670	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
J8L76_11675	COG0528	UMP kinase activity
J8L76_11685	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
J8L76_11695	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
J8L76_11715	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J8L76_11720	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J8L76_11725	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J8L76_11730	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J8L76_11735	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
J8L76_11740	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J8L76_11745	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
J8L76_11760	COG2860	membrane
J8L76_11765	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
J8L76_11770	COG2867	negative regulation of translational initiation
J8L76_11775	COG2914	Belongs to the UPF0125 (RnfH) family
J8L76_11790	COG0519	Catalyzes the synthesis of GMP from XMP
J8L76_11790	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J8L76_11810	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
J8L76_11830	COG2205	protein histidine kinase activity
J8L76_11830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J8L76_11830	COG0784	Response regulator, receiver
J8L76_11830	COG2198	Histidine kinase
J8L76_11835	COG2205	protein histidine kinase activity
J8L76_11845	COG2204	response regulator
J8L76_11865	COG0840	transmembrane signaling receptor activity
J8L76_11870	COG0483	inositol monophosphate 1-phosphatase activity
J8L76_11890	COG1104	cysteine desulfurase activity
J8L76_11895	COG1104	cysteine desulfurase activity
J8L76_11900	COG0822	iron-sulfur transferase activity
J8L76_11905	COG0316	Belongs to the HesB IscA family
J8L76_11910	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
J8L76_11915	COG0443	Heat shock 70 kDa protein
J8L76_11940	COG0560	Phosphoserine phosphatase
J8L76_11945	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J8L76_11950	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J8L76_11960	COG2078	PFAM AMMECR1 domain protein
J8L76_11960	COG3885	ferrous iron binding
J8L76_11965	COG1355	regulation of microtubule-based process
J8L76_11970	COG3174	membrane
J8L76_11975	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
J8L76_11985	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
J8L76_12015	COG0456	acetyltransferase
J8L76_12015	COG1214	PFAM Peptidase M22, glycoprotease
J8L76_12020	COG1573	uracil-dna glycosylase
J8L76_12025	COG1704	LemA family
J8L76_12040	COG0477	Major facilitator Superfamily
J8L76_12045	COG0583	DNA-binding transcription factor activity
J8L76_12050	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J8L76_12060	COG0778	Nitroreductase
J8L76_12085	COG2199	diguanylate cyclase activity
J8L76_12085	COG2200	EAL domain
J8L76_12085	COG2203	Gaf domain
J8L76_12095	COG1217	gtp-binding protein TYPA
J8L76_12100	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
J8L76_12140	COG0556	nucleotide-excision repair
J8L76_12145	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J8L76_12150	COG1530	ribonuclease E activity
J8L76_12175	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
J8L76_12180	COG0424	maF-like protein
J8L76_12185	COG1399	metal-binding, possibly nucleic acid-binding protein
J8L76_12190	COG0333	Belongs to the bacterial ribosomal protein bL32 family
J8L76_12195	COG0416	fatty acid biosynthetic process
J8L76_12200	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J8L76_12205	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
J8L76_12210	COG1028	Short-chain dehydrogenase reductase Sdr
J8L76_12215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J8L76_12220	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J8L76_12230	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
J8L76_12235	COG1595	DNA-templated transcription, initiation
J8L76_12250	COG0481	GTPase activity
J8L76_12255	COG0681	Belongs to the peptidase S26 family
J8L76_12265	COG0571	ribonuclease III activity
J8L76_12270	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
J8L76_12275	COG1381	Involved in DNA repair and RecF pathway recombination
J8L76_12280	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
J8L76_12285	COG0736	holo-[acyl-carrier-protein] synthase activity
J8L76_12290	COG1472	Belongs to the glycosyl hydrolase 3 family
J8L76_12295	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J8L76_12310	COG0322	excinuclease ABC activity
J8L76_12315	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J8L76_12375	COG0354	folic acid binding
J8L76_12380	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J8L76_12385	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
J8L76_12400	COG0084	hydrolase, TatD family'
J8L76_12455	COG0653	protein targeting
J8L76_12520	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J8L76_12525	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
J8L76_12535	COG0850	regulation of cytokinetic process
J8L76_12560	COG1648	precorrin-2 dehydrogenase activity
J8L76_12560	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J8L76_12595	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
J8L76_12600	COG2205	protein histidine kinase activity
J8L76_12605	COG0745	RESPONSE REGULATOR receiver
J8L76_12635	COG1960	acyl-CoA dehydrogenase activity
J8L76_12660	COG4181	ATPase activity
J8L76_12670	COG0709	Synthesizes selenophosphate from selenide and ATP
J8L76_12675	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
J8L76_12715	COG1309	transcriptional regulator
J8L76_12720	COG1979	alcohol dehydrogenase
J8L76_12740	COG3706	GGDEF domain
J8L76_12805	COG0840	transmembrane signaling receptor activity
J8L76_12825	COG0542	response to heat
J8L76_12835	COG0840	transmembrane signaling receptor activity
J8L76_12845	COG1199	ATP-dependent helicase activity
J8L76_12855	COG2974	May be involved in recombination
J8L76_12860	COG0776	regulation of translation
J8L76_12865	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J8L76_12870	COG0697	spore germination
J8L76_12875	COG3228	Belongs to the MtfA family
J8L76_12890	COG0658	competence protein
J8L76_12890	COG2333	competence protein COMEC
J8L76_12895	COG0840	transmembrane signaling receptor activity
J8L76_12910	COG1136	(ABC) transporter
J8L76_12925	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J8L76_12935	COG0210	DNA helicase
J8L76_12945	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
J8L76_12950	COG2205	protein histidine kinase activity
J8L76_12950	COG3437	response regulator, receiver
J8L76_12950	COG3850	Histidine kinase
J8L76_12950	COG4999	Histidine kinase
J8L76_12970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J8L76_12970	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
J8L76_12995	COG0747	negative chemotaxis
J8L76_13000	COG0601	transmembrane transport
J8L76_13005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J8L76_13010	COG2855	membrane
J8L76_13015	COG0583	DNA-binding transcription factor activity
J8L76_13030	COG1067	ATP-dependent peptidase activity
J8L76_13040	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
J8L76_13045	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J8L76_13050	COG0508	dehydrogenase complex catalyzes the overall conversion of
J8L76_13055	COG0567	Dehydrogenase, E1 component
J8L76_13065	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
J8L76_13070	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J8L76_13075	COG1053	succinate dehydrogenase
J8L76_13095	COG0039	L-malate dehydrogenase activity
J8L76_13135	COG0318	PFAM AMP-dependent synthetase and ligase
J8L76_13150	COG1127	ABC transporter
J8L76_13155	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
J8L76_13160	COG0248	Ppx GppA phosphatase
J8L76_13165	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
J8L76_13170	COG0670	Belongs to the BI1 family
J8L76_13190	COG3851	Histidine kinase
J8L76_13195	COG2197	response regulator
J8L76_13205	COG0835	chemotaxis
J8L76_13210	COG0840	transmembrane signaling receptor activity
J8L76_13215	COG0643	Histidine kinase
J8L76_13215	COG2198	Histidine kinase
J8L76_13225	COG0745	RESPONSE REGULATOR receiver
J8L76_13235	COG2197	response regulator
J8L76_13240	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J8L76_13250	COG0720	synthase
J8L76_13265	COG0527	aspartate kinase activity
J8L76_13295	COG1272	protein, Hemolysin III
J8L76_13310	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J8L76_13315	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
J8L76_13325	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
J8L76_13335	COG0776	regulation of translation
J8L76_13345	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
J8L76_13350	COG0287	Prephenate dehydrogenase
J8L76_13355	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J8L76_13365	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
J8L76_13375	COG0402	S-adenosylhomocysteine deaminase activity
J8L76_13385	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J8L76_13430	COG1639	'signal transduction protein
J8L76_13440	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J8L76_13480	COG0741	lytic transglycosylase activity
J8L76_13480	COG1388	LysM domain
J8L76_13495	COG0601	transmembrane transport
J8L76_13505	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
J8L76_13510	COG4266	Belongs to the allantoicase family
J8L76_13540	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
J8L76_13555	COG1529	Aldehyde oxidase and xanthine dehydrogenase
J8L76_13565	COG3845	ABC transporter
J8L76_13570	COG4603	Belongs to the binding-protein-dependent transport system permease family
J8L76_13575	COG1079	Belongs to the binding-protein-dependent transport system permease family
J8L76_13585	COG0402	S-adenosylhomocysteine deaminase activity
J8L76_13595	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J8L76_13595	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J8L76_13600	COG0829	nickel cation binding
J8L76_13605	COG0831	urea catabolic process
J8L76_13610	COG0832	Belongs to the urease beta subunit family
J8L76_13615	COG0804	urea catabolic process
J8L76_13625	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
J8L76_13630	COG0830	nickel cation binding
J8L76_13635	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
J8L76_13645	COG2818	Glycosylase
J8L76_13655	COG2837	iron assimilation
J8L76_13680	COG3243	poly(R)-hydroxyalkanoic acid synthase
J8L76_13695	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
J8L76_13700	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
J8L76_13705	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
J8L76_13710	COG0330	HflC and HflK could
J8L76_13715	COG0330	HflC and HflK could
J8L76_13720	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J8L76_13725	COG1923	regulation of RNA biosynthetic process
J8L76_13730	COG1160	GTP binding
J8L76_13745	COG0124	histidyl-tRNA synthetase
J8L76_13750	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
J8L76_13765	COG0820	rRNA (adenine-C2-)-methyltransferase activity
J8L76_13770	COG0105	UTP biosynthetic process
J8L76_13780	COG1301	dicarboxylic acid transport
J8L76_13795	COG0037	tRNA processing
J8L76_13800	COG0825	malonyl-CoA metabolic process
J8L76_13820	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
J8L76_13825	COG0644	oxidoreductase
J8L76_13840	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
J8L76_13845	COG0746	molybdenum cofactor guanylyltransferase activity
J8L76_13865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J8L76_13885	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J8L76_13900	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
J8L76_13905	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
J8L76_13910	COG0740	serine-type endopeptidase activity
J8L76_13915	COG0544	peptidyl-prolyl cis-trans isomerase activity
J8L76_13925	COG1562	ergosterol biosynthetic process
J8L76_13930	COG1562	ergosterol biosynthetic process
J8L76_13935	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
J8L76_13965	COG1131	(ABC) transporter
J8L76_13970	COG0842	Transport permease protein
J8L76_13990	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J8L76_13995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J8L76_14000	COG2274	protein secretion by the type I secretion system
J8L76_14020	COG2205	protein histidine kinase activity
J8L76_14035	COG0745	RESPONSE REGULATOR receiver
J8L76_14050	COG0471	metal ion transport
J8L76_14060	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J8L76_14075	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
J8L76_14080	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
J8L76_14085	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J8L76_14095	COG2951	lytic endotransglycosylase activity
J8L76_14110	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
J8L76_14115	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
J8L76_14135	COG0776	regulation of translation
J8L76_14140	COG0072	phenylalanine-tRNA ligase activity
J8L76_14140	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J8L76_14145	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
J8L76_14150	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
J8L76_14155	COG0291	Belongs to the bacterial ribosomal protein bL35 family
J8L76_14160	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
J8L76_14165	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
J8L76_14185	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J8L76_14190	COG2176	DNA-directed DNA polymerase activity
J8L76_14220	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
J8L76_14235	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J8L76_14240	COG0745	RESPONSE REGULATOR receiver
J8L76_14245	COG0604	alcohol dehydrogenase
J8L76_14250	COG0791	NLP P60 protein
J8L76_14255	COG1752	Esterase of the alpha-beta hydrolase superfamily
J8L76_14260	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
J8L76_14265	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
J8L76_14270	COG0167	dihydroorotate dehydrogenase activity
J8L76_14280	COG2878	Part of a membrane complex involved in electron transport
J8L76_14300	COG4660	Part of a membrane complex involved in electron transport
J8L76_14305	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J8L76_14320	COG0840	transmembrane signaling receptor activity
J8L76_14345	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J8L76_14350	COG0579	oxidoreductase
J8L76_14365	COG3012	SEC-C Motif Domain Protein
J8L76_14380	COG0494	nUDIX hydrolase
J8L76_14385	COG1007	ATP synthesis coupled electron transport
J8L76_14400	COG0713	ATP synthesis coupled electron transport
J8L76_14410	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J8L76_14415	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
J8L76_14420	COG1034	ATP synthesis coupled electron transport
J8L76_14430	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
J8L76_14435	COG0649	NAD binding
J8L76_14440	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J8L76_14445	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J8L76_14450	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J8L76_14465	COG0149	triose-phosphate isomerase activity
J8L76_14470	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J8L76_14475	COG0581	inorganic phosphate transmembrane transporter activity
J8L76_14480	COG0573	inorganic phosphate transmembrane transporter activity
J8L76_14485	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
J8L76_14490	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J8L76_14500	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J8L76_14505	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
J8L76_14520	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J8L76_14525	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J8L76_14530	COG0505	Belongs to the CarA family
J8L76_14535	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
J8L76_14540	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J8L76_14545	COG0735	belongs to the Fur family
J8L76_14560	COG0497	DNA recombination
J8L76_14565	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J8L76_14570	COG1420	regulation of RNA biosynthetic process
J8L76_14575	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
J8L76_14600	COG0515	serine threonine protein kinase
J8L76_14600	COG2815	serine threonine protein kinase
J8L76_14605	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
J8L76_14610	COG0443	Heat shock 70 kDa protein
J8L76_14615	COG0484	heat shock protein binding
J8L76_14620	COG0683	leucine binding
J8L76_14625	COG0215	cysteine-tRNA ligase activity
J8L76_14640	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J8L76_14650	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J8L76_14660	COG0861	Integral membrane protein TerC family
J8L76_14665	COG1881	PFAM PEBP family protein
J8L76_14675	COG0514	ATP-dependent DNA helicase (RecQ)
J8L76_14690	COG0513	Belongs to the DEAD box helicase family
J8L76_14720	COG0285	dihydrofolate synthase activity
J8L76_14725	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
J8L76_14730	COG0159	tryptophan synthase activity
J8L76_14735	COG0133	tryptophan synthase activity
J8L76_14740	COG0135	phosphoribosylanthranilate isomerase activity
J8L76_14745	COG0101	tRNA pseudouridine synthase activity