locus-tag	class	description
AZSP09_00010	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AZSP09_00020	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AZSP09_00030	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AZSP09_00040	COG0723	plastoquinol--plastocyanin reductase activity
AZSP09_00050	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AZSP09_00060	COG2857	Cytochrome c1
AZSP09_00070	COG0625	glutathione transferase activity
AZSP09_00090	COG2969	positive regulation of protein catabolic process
AZSP09_00100	COG0243	molybdopterin cofactor binding
AZSP09_00110	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AZSP09_00120	COG1942	4-Oxalocrotonate Tautomerase
AZSP09_00180	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AZSP09_00190	COG2146	nitrite reductase [NAD(P)H] activity
AZSP09_00210	COG3707	response regulator
AZSP09_00240	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZSP09_00260	COG1116	anion transmembrane transporter activity
AZSP09_00280	COG0438	transferase activity, transferring glycosyl groups
AZSP09_00380	COG0306	phosphate transporter
AZSP09_00390	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
AZSP09_00410	COG0798	PFAM Bile acid sodium symporter
AZSP09_00420	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AZSP09_00450	COG2205	protein histidine kinase activity
AZSP09_00460	COG0745	RESPONSE REGULATOR receiver
AZSP09_00500	COG1942	4-Oxalocrotonate Tautomerase
AZSP09_00520	COG0583	DNA-binding transcription factor activity
AZSP09_00540	COG0840	transmembrane signaling receptor activity
AZSP09_00590	COG3920	Histidine kinase
AZSP09_00600	COG2205	protein histidine kinase activity
AZSP09_00600	COG0784	Response regulator, receiver
AZSP09_00600	COG5002	protein histidine kinase activity
AZSP09_00610	COG0745	RESPONSE REGULATOR receiver
AZSP09_00620	COG2205	protein histidine kinase activity
AZSP09_00620	COG4999	Histidine kinase
AZSP09_00620	COG3850	Histidine kinase
AZSP09_00620	COG3437	response regulator, receiver
AZSP09_00650	COG1538	Outer membrane efflux protein
AZSP09_00690	COG1742	UPF0060 membrane protein
AZSP09_00700	COG3058	Necessary for formate dehydrogenase activity
AZSP09_00710	COG3383	formate dehydrogenase (NAD+) activity
AZSP09_00710	COG0243	molybdopterin cofactor binding
AZSP09_00720	COG0437	4 iron, 4 sulfur cluster binding
AZSP09_00730	COG2864	formate dehydrogenase
AZSP09_00740	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AZSP09_00750	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AZSP09_00810	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AZSP09_00840	COG1570	exodeoxyribonuclease VII activity
AZSP09_00850	COG0811	peptide transport
AZSP09_00860	COG0848	biopolymer transport protein
AZSP09_00870	COG1663	tetraacyldisaccharide 4'-kinase activity
AZSP09_00880	COG2835	tetraacyldisaccharide 4'-kinase activity
AZSP09_00890	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AZSP09_00900	COG0563	adenylate kinase activity
AZSP09_00910	COG0205	6-phosphofructokinase activity
AZSP09_00920	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AZSP09_00930	COG1028	Short-chain dehydrogenase reductase Sdr
AZSP09_00950	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AZSP09_00960	COG1881	PFAM PEBP family protein
AZSP09_00980	COG0268	Binds directly to 16S ribosomal RNA
AZSP09_01010	COG1192	Involved in chromosome partitioning
AZSP09_01020	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AZSP09_01030	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AZSP09_01040	COG0137	argininosuccinate synthase activity
AZSP09_01060	COG3123	guanosine phosphorylase activity
AZSP09_01070	COG1666	GTP binding
AZSP09_01080	COG0505	Belongs to the CarA family
AZSP09_01110	COG0494	nUDIX hydrolase
AZSP09_01130	COG0183	Belongs to the thiolase family
AZSP09_01140	COG0840	transmembrane signaling receptor activity
AZSP09_01150	COG0840	transmembrane signaling receptor activity
AZSP09_01160	COG2308	Evidence 4 Homologs of previously reported genes of
AZSP09_01200	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
AZSP09_01230	COG1305	Transglutaminase-like
AZSP09_01250	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AZSP09_01260	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
AZSP09_01280	COG1162	GTPase activity
AZSP09_01290	COG2154	pterin-4-alpha-carbinolamine dehydratase
AZSP09_01310	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AZSP09_01340	COG0254	rRNA binding
AZSP09_01350	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AZSP09_01370	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AZSP09_01390	COG1074	ATP-dependent DNA helicase activity
AZSP09_01410	COG0318	PFAM AMP-dependent synthetase and ligase
AZSP09_01490	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AZSP09_01520	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AZSP09_01540	COG0066	3-isopropylmalate dehydratase activity
AZSP09_01550	COG0473	3-isopropylmalate dehydrogenase activity
AZSP09_01590	COG0101	tRNA pseudouridine synthase activity
AZSP09_01600	COG0135	phosphoribosylanthranilate isomerase activity
AZSP09_01610	COG0133	tryptophan synthase activity
AZSP09_01620	COG0159	tryptophan synthase activity
AZSP09_01630	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AZSP09_01640	COG0285	dihydrofolate synthase activity
AZSP09_01700	COG1538	Outer membrane efflux protein
AZSP09_01710	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AZSP09_01720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZSP09_01730	COG0745	RESPONSE REGULATOR receiver
AZSP09_01740	COG2205	protein histidine kinase activity
AZSP09_01750	COG1136	(ABC) transporter
AZSP09_01750	COG0577	efflux transmembrane transporter activity
AZSP09_01760	COG1136	(ABC) transporter
AZSP09_01760	COG0577	efflux transmembrane transporter activity
AZSP09_01790	COG0513	Belongs to the DEAD box helicase family
AZSP09_01800	COG0583	DNA-binding transcription factor activity
AZSP09_01860	COG0825	malonyl-CoA metabolic process
AZSP09_01870	COG0037	tRNA processing
AZSP09_01880	COG3706	GGDEF domain
AZSP09_01880	COG0745	RESPONSE REGULATOR receiver
AZSP09_01940	COG1301	dicarboxylic acid transport
AZSP09_02000	COG2205	protein histidine kinase activity
AZSP09_02010	COG0745	RESPONSE REGULATOR receiver
AZSP09_02040	COG0644	oxidoreductase
AZSP09_02060	COG0105	UTP biosynthetic process
AZSP09_02070	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AZSP09_02100	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AZSP09_02110	COG0124	histidyl-tRNA synthetase
AZSP09_02130	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AZSP09_02140	COG1160	GTP binding
AZSP09_02150	COG1923	regulation of RNA biosynthetic process
AZSP09_02160	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AZSP09_02170	COG0330	HflC and HflK could
AZSP09_02180	COG0330	HflC and HflK could
AZSP09_02200	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AZSP09_02210	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AZSP09_02220	COG0557	exoribonuclease II activity
AZSP09_02260	COG0745	RESPONSE REGULATOR receiver
AZSP09_02270	COG0840	transmembrane signaling receptor activity
AZSP09_02280	COG0840	transmembrane signaling receptor activity
AZSP09_02360	COG1845	cytochrome c oxidase, subunit III
AZSP09_02420	COG2010	Cytochrome c
AZSP09_02440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZSP09_02460	COG1253	flavin adenine dinucleotide binding
AZSP09_02490	COG0746	molybdenum cofactor guanylyltransferase activity
AZSP09_02500	COG0583	DNA-binding transcription factor activity
AZSP09_02530	COG3145	DNA-N1-methyladenine dioxygenase activity
AZSP09_02540	COG2169	Transcriptional regulator
AZSP09_02540	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AZSP09_02570	COG1418	mRNA catabolic process
AZSP09_02580	COG0514	ATP-dependent DNA helicase (RecQ)
AZSP09_02590	COG0861	Integral membrane protein TerC family
AZSP09_02610	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AZSP09_02660	COG0215	cysteine-tRNA ligase activity
AZSP09_02680	COG0484	heat shock protein binding
AZSP09_02690	COG0443	Heat shock 70 kDa protein
AZSP09_02700	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AZSP09_02710	COG0515	serine threonine protein kinase
AZSP09_02710	COG2815	serine threonine protein kinase
AZSP09_02720	COG0840	transmembrane signaling receptor activity
AZSP09_02740	COG3118	belongs to the thioredoxin family
AZSP09_02750	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AZSP09_02760	COG1420	regulation of RNA biosynthetic process
AZSP09_02770	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AZSP09_02780	COG0497	DNA recombination
AZSP09_02810	COG2119	membrane
AZSP09_02820	COG0735	belongs to the Fur family
AZSP09_02830	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AZSP09_02840	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AZSP09_02850	COG0505	Belongs to the CarA family
AZSP09_02860	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AZSP09_02870	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AZSP09_02890	COG1534	Rna-binding protein
AZSP09_02900	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AZSP09_02910	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AZSP09_02930	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AZSP09_02940	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AZSP09_02950	COG0573	inorganic phosphate transmembrane transporter activity
AZSP09_02970	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AZSP09_02980	COG0149	triose-phosphate isomerase activity
AZSP09_03000	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AZSP09_03010	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AZSP09_03020	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AZSP09_03030	COG0649	NAD binding
AZSP09_03040	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AZSP09_03060	COG1034	ATP synthesis coupled electron transport
AZSP09_03070	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AZSP09_03080	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AZSP09_03100	COG0713	ATP synthesis coupled electron transport
AZSP09_03130	COG1007	ATP synthesis coupled electron transport
AZSP09_03140	COG0494	nUDIX hydrolase
AZSP09_03150	COG3706	GGDEF domain
AZSP09_03160	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AZSP09_03170	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AZSP09_03190	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AZSP09_03200	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AZSP09_03210	COG3383	formate dehydrogenase (NAD+) activity
AZSP09_03220	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
AZSP09_03230	COG3259	Nickel-dependent hydrogenase
AZSP09_03270	COG0306	phosphate transporter
AZSP09_03310	COG0596	Alpha beta hydrolase
AZSP09_03310	COG0508	dehydrogenase complex catalyzes the overall conversion of
AZSP09_03380	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AZSP09_03390	COG0437	4 iron, 4 sulfur cluster binding
AZSP09_03400	COG5557	Pfam Polysulphide reductase, NrfD
AZSP09_03410	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AZSP09_03420	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AZSP09_03460	COG3706	GGDEF domain
AZSP09_03460	COG0745	RESPONSE REGULATOR receiver
AZSP09_03470	COG0326	Molecular chaperone. Has ATPase activity
AZSP09_03480	COG4191	Histidine kinase
AZSP09_03510	COG4191	Histidine kinase
AZSP09_03540	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AZSP09_03560	COG0406	alpha-ribazole phosphatase activity
AZSP09_03590	COG0745	RESPONSE REGULATOR receiver
AZSP09_03590	COG3706	GGDEF domain
AZSP09_03610	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AZSP09_03620	COG0840	transmembrane signaling receptor activity
AZSP09_03630	COG0840	transmembrane signaling receptor activity
AZSP09_03670	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AZSP09_03720	COG2878	Part of a membrane complex involved in electron transport
AZSP09_03730	COG4657	Part of a membrane complex involved in electron transport
AZSP09_03740	COG0167	dihydroorotate dehydrogenase activity
AZSP09_03750	COG1595	DNA-templated transcription, initiation
AZSP09_03790	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AZSP09_03800	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AZSP09_03810	COG1752	Esterase of the alpha-beta hydrolase superfamily
AZSP09_03830	COG1648	precorrin-2 dehydrogenase activity
AZSP09_03830	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AZSP09_03900	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
AZSP09_03940	COG1122	ATPase activity
AZSP09_03970	COG0310	cobalt ion transport
AZSP09_04000	COG3706	GGDEF domain
AZSP09_04020	COG1451	nucleotide metabolic process
AZSP09_04030	COG0513	Belongs to the DEAD box helicase family
AZSP09_04050	COG3842	ATPase activity
AZSP09_04060	COG1178	ABC-type Fe3 transport system permease component
AZSP09_04110	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AZSP09_04120	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AZSP09_04130	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AZSP09_04140	COG5310	Homospermidine synthase
AZSP09_04150	COG0754	glutathionylspermidine amidase activity
AZSP09_04230	COG1840	ABC-type Fe3 transport system, periplasmic component
AZSP09_04240	COG0791	NLP P60 protein
AZSP09_04260	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AZSP09_04290	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AZSP09_04300	COG1169	isochorismate synthase
AZSP09_04360	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
AZSP09_04380	COG0726	polysaccharide deacetylase
AZSP09_04390	COG2076	Multidrug Resistance protein
AZSP09_04410	COG0436	Aminotransferase
AZSP09_04420	COG0436	Aminotransferase
AZSP09_04470	COG2890	protein-(glutamine-N5) methyltransferase activity
AZSP09_04500	COG0069	glutamate synthase activity
AZSP09_04520	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AZSP09_04520	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AZSP09_04570	COG5002	protein histidine kinase activity
AZSP09_04570	COG5001	Diguanylate cyclase
AZSP09_04580	COG3706	GGDEF domain
AZSP09_04590	COG0047	phosphoribosylformylglycinamidine synthase activity
AZSP09_04590	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AZSP09_04610	COG2200	EAL domain
AZSP09_04620	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AZSP09_04640	COG2350	Protein conserved in bacteria
AZSP09_04650	COG2917	probably involved in intracellular septation
AZSP09_04670	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AZSP09_04680	COG2226	methyltransferase
AZSP09_04690	COG2267	carboxylic ester hydrolase activity
AZSP09_04700	COG0156	8-amino-7-oxononanoate synthase activity
AZSP09_04720	COG0840	transmembrane signaling receptor activity
AZSP09_04730	COG0577	efflux transmembrane transporter activity
AZSP09_04730	COG1136	(ABC) transporter
AZSP09_04740	COG0577	efflux transmembrane transporter activity
AZSP09_04740	COG1136	(ABC) transporter
AZSP09_04750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZSP09_04780	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AZSP09_04820	COG0583	DNA-binding transcription factor activity
AZSP09_04830	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AZSP09_04830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZSP09_04870	COG0784	Response regulator, receiver
AZSP09_04870	COG2205	protein histidine kinase activity
AZSP09_04870	COG5002	protein histidine kinase activity
AZSP09_04880	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AZSP09_04890	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AZSP09_04900	COG0697	spore germination
AZSP09_04910	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AZSP09_04940	COG1136	(ABC) transporter
AZSP09_04960	COG0840	transmembrane signaling receptor activity
AZSP09_04990	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AZSP09_05000	COG0596	Alpha beta hydrolase
AZSP09_05020	COG3228	Belongs to the MtfA family
AZSP09_05040	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AZSP09_05050	COG0431	NADPH-dependent FMN reductase
AZSP09_05060	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AZSP09_05070	COG0248	Ppx GppA phosphatase
AZSP09_05080	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AZSP09_05090	COG1127	ABC transporter
AZSP09_05120	COG0318	PFAM AMP-dependent synthetase and ligase
AZSP09_05130	COG1024	Enoyl-CoA hydratase
AZSP09_05140	COG4191	Histidine kinase
AZSP09_05190	COG0601	transmembrane transport
AZSP09_05200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZSP09_05220	COG2814	Major facilitator Superfamily
AZSP09_05230	COG0741	lytic transglycosylase activity
AZSP09_05230	COG1388	LysM domain
AZSP09_05240	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AZSP09_05250	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AZSP09_05260	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AZSP09_05270	COG0187	DNA topoisomerase II activity
AZSP09_05290	COG0784	Response regulator, receiver
AZSP09_05290	COG2205	protein histidine kinase activity
AZSP09_05320	COG0784	Response regulator, receiver
AZSP09_05330	COG0642	Histidine kinase
AZSP09_05360	COG2195	Cleaves the N-terminal amino acid of tripeptides
AZSP09_05380	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AZSP09_05420	COG4681	YaeQ
AZSP09_05430	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AZSP09_05500	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AZSP09_05530	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AZSP09_05540	COG1187	pseudouridine synthase activity
AZSP09_05560	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AZSP09_05590	COG0826	peptidase U32
AZSP09_05610	COG1132	(ABC) transporter
AZSP09_05660	COG3739	integral membrane protein
AZSP09_05670	COG0488	(ABC) transporter
AZSP09_05710	COG0443	Heat shock 70 kDa protein
AZSP09_05740	COG0508	dehydrogenase complex catalyzes the overall conversion of
AZSP09_05760	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AZSP09_05760	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AZSP09_05770	COG0509	glycine decarboxylation via glycine cleavage system
AZSP09_05780	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AZSP09_05820	COG0613	PHP domain protein
AZSP09_05830	COG0009	L-threonylcarbamoyladenylate synthase
AZSP09_05840	COG1994	Peptidase M50
AZSP09_05850	COG0180	Tryptophanyl-tRNA synthetase
AZSP09_05860	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AZSP09_05870	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AZSP09_05880	COG1187	pseudouridine synthase activity
AZSP09_05890	COG0779	Required for maturation of 30S ribosomal subunits
AZSP09_05900	COG2251	uridine kinase activity
AZSP09_05900	COG0195	Participates in both transcription termination and antitermination
AZSP09_05910	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AZSP09_05920	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AZSP09_05930	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AZSP09_05940	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AZSP09_05950	COG1185	polyribonucleotide nucleotidyltransferase activity
AZSP09_05960	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AZSP09_05970	COG0330	HflC and HflK could
AZSP09_05990	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AZSP09_06010	COG2171	N-acyltransferase activity
AZSP09_06020	COG0436	Aminotransferase
AZSP09_06040	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AZSP09_06050	COG2252	PERMEase
AZSP09_06060	COG3318	Belongs to the UPF0149 family
AZSP09_06060	COG3012	SEC-C Motif Domain Protein
AZSP09_06090	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AZSP09_06100	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AZSP09_06130	COG0242	peptide deformylase activity
AZSP09_06140	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AZSP09_06150	COG0024	Methionine aminopeptidase
AZSP09_06160	COG0052	Belongs to the universal ribosomal protein uS2 family
AZSP09_06170	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AZSP09_06180	COG0528	UMP kinase activity
AZSP09_06190	COG0233	cytoplasmic translational termination
AZSP09_06200	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AZSP09_06210	COG0575	Belongs to the CDS family
AZSP09_06220	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AZSP09_06240	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AZSP09_06260	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AZSP09_06270	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AZSP09_06280	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AZSP09_06290	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AZSP09_06300	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AZSP09_06310	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AZSP09_06320	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AZSP09_06340	COG2860	membrane
AZSP09_06350	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AZSP09_06360	COG2867	negative regulation of translational initiation
AZSP09_06370	COG2914	Belongs to the UPF0125 (RnfH) family
AZSP09_06400	COG0519	Catalyzes the synthesis of GMP from XMP
AZSP09_06400	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AZSP09_06440	COG1733	regulation of RNA biosynthetic process
AZSP09_06450	COG0702	epimerase
AZSP09_06490	COG0590	tRNA wobble adenosine to inosine editing
AZSP09_06510	COG1278	Cold shock
AZSP09_06540	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AZSP09_06550	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AZSP09_06580	COG0084	hydrolase, TatD family'
AZSP09_06600	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AZSP09_06640	COG4644	lycopene metabolic process
AZSP09_06660	COG0789	Transcriptional regulator
AZSP09_06670	COG1742	UPF0060 membrane protein
AZSP09_06690	COG5002	protein histidine kinase activity
AZSP09_06760	COG3039	Transposase
AZSP09_06770	COG1815	bacterial-type flagellum-dependent cell motility
AZSP09_06790	COG2119	membrane
AZSP09_06830	COG1959	2 iron, 2 sulfur cluster binding
AZSP09_06840	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
AZSP09_06850	COG5001	Diguanylate cyclase
AZSP09_06850	COG3300	MHYT domain
AZSP09_06860	COG2183	response to ionizing radiation
AZSP09_06870	COG1393	Belongs to the ArsC family
AZSP09_06880	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AZSP09_06900	COG0277	FAD linked oxidase domain protein
AZSP09_06910	COG1752	Esterase of the alpha-beta hydrolase superfamily
AZSP09_06920	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AZSP09_06930	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
AZSP09_06950	COG3243	poly(R)-hydroxyalkanoic acid synthase
AZSP09_06990	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AZSP09_07000	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AZSP09_07020	COG0564	pseudouridine synthase activity
AZSP09_07040	COG2815	serine threonine protein kinase
AZSP09_07040	COG0515	serine threonine protein kinase
AZSP09_07070	COG1322	Protein conserved in bacteria
AZSP09_07080	COG2203	Gaf domain
AZSP09_07080	COG3706	GGDEF domain
AZSP09_07080	COG4251	negative regulation of phosphorylation
AZSP09_07080	COG5001	Diguanylate cyclase
AZSP09_07090	COG2201	protein-glutamate methylesterase activity
AZSP09_07100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZSP09_07110	COG2226	methyltransferase
AZSP09_07120	COG0328	RNA-DNA hybrid ribonuclease activity
AZSP09_07130	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AZSP09_07190	COG0322	excinuclease ABC activity
AZSP09_07220	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AZSP09_07230	COG1793	dna ligase
AZSP09_07240	COG1472	Belongs to the glycosyl hydrolase 3 family
AZSP09_07250	COG0736	holo-[acyl-carrier-protein] synthase activity
AZSP09_07260	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AZSP09_07270	COG1381	Involved in DNA repair and RecF pathway recombination
AZSP09_07280	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AZSP09_07290	COG0571	ribonuclease III activity
AZSP09_07310	COG0681	Belongs to the peptidase S26 family
AZSP09_07320	COG0481	GTPase activity
AZSP09_07340	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AZSP09_07360	COG1595	DNA-templated transcription, initiation
AZSP09_07370	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AZSP09_07390	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AZSP09_07400	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AZSP09_07430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AZSP09_07440	COG0416	fatty acid biosynthetic process
AZSP09_07450	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AZSP09_07460	COG1399	metal-binding, possibly nucleic acid-binding protein
AZSP09_07470	COG0424	maF-like protein
AZSP09_07480	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AZSP09_07490	COG0616	signal peptide processing
AZSP09_07490	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AZSP09_07530	COG1530	ribonuclease E activity
AZSP09_07540	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AZSP09_07550	COG0556	nucleotide-excision repair
AZSP09_07600	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AZSP09_07650	COG3287	FIST C domain
AZSP09_07650	COG2200	EAL domain
AZSP09_07650	COG2199	diguanylate cyclase activity
AZSP09_07660	COG1032	radical SAM domain protein
AZSP09_07710	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AZSP09_07740	COG5001	Diguanylate cyclase
AZSP09_07750	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AZSP09_07760	COG0583	DNA-binding transcription factor activity
AZSP09_07770	COG0477	Major facilitator Superfamily
AZSP09_07790	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AZSP09_07800	COG1704	LemA family
AZSP09_07810	COG1573	uracil-dna glycosylase
AZSP09_07820	COG0456	acetyltransferase
AZSP09_07850	COG0745	RESPONSE REGULATOR receiver
AZSP09_07870	COG0671	phosphoesterase, PA-phosphatase related
AZSP09_07950	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AZSP09_07960	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AZSP09_07980	COG1355	regulation of microtubule-based process
AZSP09_08010	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AZSP09_08050	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AZSP09_08060	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AZSP09_08070	COG0560	Phosphoserine phosphatase
AZSP09_08110	COG0443	Heat shock 70 kDa protein
AZSP09_08120	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AZSP09_08150	COG0822	iron-sulfur transferase activity
AZSP09_08160	COG1104	cysteine desulfurase activity
AZSP09_08170	COG1104	cysteine desulfurase activity
AZSP09_08190	COG1045	serine acetyltransferase
AZSP09_08270	COG2204	response regulator
AZSP09_08290	COG2205	protein histidine kinase activity
AZSP09_08300	COG2353	YceI-like domain
AZSP09_08320	COG3038	cytochrome b561
AZSP09_08330	COG3384	dioxygenase
AZSP09_08340	COG0583	DNA-binding transcription factor activity
AZSP09_08370	COG0789	Transcriptional regulator
AZSP09_08380	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AZSP09_08400	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AZSP09_08420	COG2501	S4 domain
AZSP09_08450	COG1131	(ABC) transporter
AZSP09_08460	COG0842	Transport permease protein
AZSP09_08470	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AZSP09_08510	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AZSP09_08520	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AZSP09_08550	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZSP09_08630	COG3210	domain, Protein
AZSP09_08640	COG2831	hemolysin activation secretion protein
AZSP09_08670	COG3012	SEC-C Motif Domain Protein
AZSP09_08700	COG3022	response to hydroperoxide
AZSP09_08740	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AZSP09_08750	COG0148	phosphopyruvate hydratase activity
AZSP09_08780	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AZSP09_08790	COG0504	CTP synthase activity
AZSP09_08800	COG1028	Short-chain dehydrogenase reductase Sdr
AZSP09_08810	COG1335	isochorismatase
AZSP09_08820	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AZSP09_08830	COG0709	Synthesizes selenophosphate from selenide and ATP
AZSP09_08850	COG4181	ATPase activity
AZSP09_08860	COG1309	transcriptional regulator
AZSP09_08900	COG1960	acyl-CoA dehydrogenase activity
AZSP09_08910	COG2200	EAL domain
AZSP09_08950	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AZSP09_08960	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AZSP09_08990	COG3243	poly(R)-hydroxyalkanoic acid synthase
AZSP09_09020	COG2995	paraquat-inducible protein a
AZSP09_09030	COG3008	intermembrane lipid transfer
AZSP09_09030	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AZSP09_09050	COG0308	aminopeptidase N
AZSP09_09120	COG3501	Rhs element vgr protein
AZSP09_09140	COG3655	Transcriptional regulator
AZSP09_09200	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AZSP09_09240	COG0587	DNA-directed DNA polymerase activity
AZSP09_09250	COG3550	peptidyl-serine autophosphorylation
AZSP09_09260	COG0587	DNA-directed DNA polymerase activity
AZSP09_09340	COG0583	DNA-binding transcription factor activity
AZSP09_09370	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AZSP09_09380	COG3135	benzoate transporter
AZSP09_09410	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AZSP09_09430	COG0745	RESPONSE REGULATOR receiver
AZSP09_09470	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AZSP09_09510	COG5002	protein histidine kinase activity
AZSP09_09510	COG0784	Response regulator, receiver
AZSP09_09510	COG2205	protein histidine kinase activity
AZSP09_09520	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AZSP09_09530	COG0747	negative chemotaxis
AZSP09_09540	COG0601	transmembrane transport
AZSP09_09550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZSP09_09580	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AZSP09_09640	COG0583	DNA-binding transcription factor activity
AZSP09_09660	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AZSP09_09690	COG2832	Protein of unknown function (DUF454)
AZSP09_09700	COG1067	ATP-dependent peptidase activity
AZSP09_09720	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AZSP09_09740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AZSP09_09750	COG0508	dehydrogenase complex catalyzes the overall conversion of
AZSP09_09760	COG0567	Dehydrogenase, E1 component
AZSP09_09780	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AZSP09_09800	COG1053	succinate dehydrogenase
AZSP09_09820	COG2009	succinate dehydrogenase
AZSP09_09840	COG0039	L-malate dehydrogenase activity
AZSP09_09930	COG2948	multi-organism process
AZSP09_09980	COG3451	type IV secretory pathway VirB4
AZSP09_10000	COG3838	Conjugal transfer protein Trbc
AZSP09_10010	COG4962	Type ii secretion system protein e
AZSP09_10050	COG0583	DNA-binding transcription factor activity
AZSP09_10060	COG1846	Transcriptional regulator
AZSP09_10110	COG1764	response to oxidative stress
AZSP09_10130	COG4959	Type IV secretory pathway protease TraF
AZSP09_10160	COG1192	Involved in chromosome partitioning
AZSP09_10230	COG5489	Protein of unknown function (DUF736)
AZSP09_10310	COG2003	Belongs to the UPF0758 family
AZSP09_10430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AZSP09_10450	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AZSP09_10460	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AZSP09_10470	COG0740	serine-type endopeptidase activity
AZSP09_10480	COG0544	peptidyl-prolyl cis-trans isomerase activity
AZSP09_10490	COG1562	ergosterol biosynthetic process
AZSP09_10500	COG1562	ergosterol biosynthetic process
AZSP09_10510	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AZSP09_10550	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AZSP09_10570	COG0519	Catalyzes the synthesis of GMP from XMP
AZSP09_10630	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AZSP09_10690	COG1764	response to oxidative stress
AZSP09_10700	COG1846	Transcriptional regulator
AZSP09_10740	COG2819	hydrolase of the alpha beta superfamily
AZSP09_10810	COG0542	response to heat
AZSP09_10830	COG0840	transmembrane signaling receptor activity
AZSP09_10840	COG2197	response regulator
AZSP09_10860	COG0840	transmembrane signaling receptor activity
AZSP09_10870	COG0314	molybdopterin synthase activity
AZSP09_10880	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AZSP09_10890	COG0303	'Molybdopterin
AZSP09_10900	COG1763	Mo-molybdopterin cofactor biosynthetic process
AZSP09_10920	COG1199	ATP-dependent helicase activity
AZSP09_10940	COG2974	May be involved in recombination
AZSP09_10950	COG0776	regulation of translation
AZSP09_11030	COG0720	synthase
AZSP09_11060	COG0527	aspartate kinase activity
AZSP09_11090	COG0776	regulation of translation
AZSP09_11120	COG0686	Belongs to the AlaDH PNT family
AZSP09_11140	COG0840	transmembrane signaling receptor activity
AZSP09_11150	COG2200	EAL domain
AZSP09_11150	COG3287	FIST C domain
AZSP09_11150	COG2199	diguanylate cyclase activity
AZSP09_11160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZSP09_11170	COG1116	anion transmembrane transporter activity
AZSP09_11210	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AZSP09_11220	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AZSP09_11240	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AZSP09_11250	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AZSP09_11260	COG1595	DNA-templated transcription, initiation
AZSP09_11270	COG4944	Protein of unknown function (DUF1109)
AZSP09_11290	COG1979	alcohol dehydrogenase
AZSP09_11300	COG0583	DNA-binding transcription factor activity
AZSP09_11320	COG1045	serine acetyltransferase
AZSP09_11330	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AZSP09_11340	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AZSP09_11380	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
AZSP09_11420	COG1595	DNA-templated transcription, initiation
AZSP09_11440	COG1408	metallophosphoesterase
AZSP09_11480	COG1285	pathogenesis
AZSP09_11490	COG0583	DNA-binding transcription factor activity
AZSP09_11510	COG3258	Cytochrome c
AZSP09_11520	COG2863	cytochrome
AZSP09_11560	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AZSP09_11570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZSP09_11580	COG4566	intracellular signal transduction
AZSP09_11590	COG4191	Histidine kinase
AZSP09_11600	COG4654	Cytochrome c, class I
AZSP09_11630	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AZSP09_11670	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AZSP09_11710	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AZSP09_11720	COG2011	ABC-type metal ion transport system permease component
AZSP09_11760	COG0683	leucine binding
AZSP09_11770	COG0559	Belongs to the binding-protein-dependent transport system permease family
AZSP09_11790	COG0411	ABC transporter
AZSP09_11840	COG1403	HNH endonuclease
AZSP09_11880	COG4178	(ABC) transporter
AZSP09_11940	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AZSP09_11950	COG0626	cystathionine gamma-synthase activity
AZSP09_11960	COG1024	Enoyl-CoA hydratase
AZSP09_11970	COG1832	CoA-binding protein
AZSP09_12020	COG0583	DNA-binding transcription factor activity
AZSP09_12030	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AZSP09_12040	COG0583	DNA-binding transcription factor activity
AZSP09_12100	COG2827	Endonuclease containing a URI domain
AZSP09_12110	COG1538	Outer membrane efflux protein
AZSP09_12130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZSP09_12150	COG0583	DNA-binding transcription factor activity
AZSP09_12160	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AZSP09_12200	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AZSP09_12240	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AZSP09_12250	COG2176	DNA-directed DNA polymerase activity
AZSP09_12270	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AZSP09_12310	COG0251	oxidation-reduction process
AZSP09_12330	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AZSP09_12340	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AZSP09_12370	COG0305	Participates in initiation and elongation during chromosome replication
AZSP09_12380	COG0359	binds to the 23S rRNA
AZSP09_12390	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AZSP09_12400	COG2965	DNA replication, synthesis of RNA primer
AZSP09_12410	COG0360	Binds together with S18 to 16S ribosomal RNA
AZSP09_12420	COG0583	DNA-binding transcription factor activity
AZSP09_12430	COG0730	response to heat
AZSP09_12460	COG0175	sulfate reduction
AZSP09_12480	COG2895	sulfate adenylyltransferase (ATP) activity
AZSP09_12490	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AZSP09_12530	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AZSP09_12540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AZSP09_12550	COG0123	including yeast histone deacetylase and acetoin utilization protein
AZSP09_12560	COG0714	Associated with various cellular activities
AZSP09_12590	COG2951	lytic endotransglycosylase activity
AZSP09_12620	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AZSP09_12630	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AZSP09_12660	COG0776	regulation of translation
AZSP09_12670	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AZSP09_12670	COG0072	phenylalanine-tRNA ligase activity
AZSP09_12680	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AZSP09_12690	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AZSP09_12700	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AZSP09_12710	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AZSP09_12720	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AZSP09_12760	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AZSP09_12770	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AZSP09_12830	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AZSP09_12850	COG0776	regulation of translation
AZSP09_12870	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AZSP09_12900	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AZSP09_12930	COG0402	S-adenosylhomocysteine deaminase activity
AZSP09_12950	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AZSP09_12960	COG0546	phosphoglycolate phosphatase activity
AZSP09_13030	COG0440	acetolactate synthase activity
AZSP09_13040	COG0028	Belongs to the TPP enzyme family
AZSP09_13060	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AZSP09_13060	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AZSP09_13070	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AZSP09_13080	COG4771	TonB-dependent receptor
AZSP09_13110	COG1429	ligase activity, forming nitrogen-metal bonds
AZSP09_13120	COG1944	ATP diphosphatase activity
AZSP09_13130	COG1294	oxidase, subunit
AZSP09_13180	COG1475	DNA binding
AZSP09_13200	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AZSP09_13210	COG0583	DNA-binding transcription factor activity
AZSP09_13220	COG1811	Na channel or pump
AZSP09_13230	COG4999	Histidine kinase
AZSP09_13230	COG3850	Histidine kinase
AZSP09_13230	COG3437	response regulator, receiver
AZSP09_13230	COG2205	protein histidine kinase activity
AZSP09_13240	COG1448	Aminotransferase
AZSP09_13280	COG3634	alkyl hydroperoxide reductase activity
AZSP09_13310	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AZSP09_13340	COG2814	Major facilitator Superfamily
AZSP09_13360	COG1704	LemA family
AZSP09_13390	COG0583	DNA-binding transcription factor activity
AZSP09_13400	COG4948	Mandelate Racemase Muconate Lactonizing
AZSP09_13430	COG1418	mRNA catabolic process
AZSP09_13430	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AZSP09_13460	COG2204	response regulator
AZSP09_13510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZSP09_13520	COG0697	spore germination
AZSP09_13530	COG1902	pentaerythritol trinitrate reductase activity
AZSP09_13540	COG1309	transcriptional regulator
AZSP09_13560	COG5002	protein histidine kinase activity
AZSP09_13570	COG2204	response regulator
AZSP09_13590	COG1366	Belongs to the anti-sigma-factor antagonist family
AZSP09_13610	COG3161	chorismate lyase activity
AZSP09_13650	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AZSP09_13670	COG0538	isocitrate dehydrogenase activity
AZSP09_13690	COG4651	solute:proton antiporter activity
AZSP09_13690	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AZSP09_13700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AZSP09_13730	COG1129	ABC transporter
AZSP09_13740	COG0348	domain, Protein
AZSP09_13750	COG0437	4 iron, 4 sulfur cluster binding
AZSP09_13790	COG2863	cytochrome
AZSP09_13800	COG4263	nitrous-oxide reductase activity
AZSP09_13820	COG1999	signal sequence binding
AZSP09_13890	COG2010	Cytochrome c
AZSP09_13900	COG1648	precorrin-2 dehydrogenase activity
AZSP09_13900	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AZSP09_13910	COG1575	Belongs to the MenA family. Type 1 subfamily
AZSP09_13920	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AZSP09_13930	COG0343	queuine tRNA-ribosyltransferase activity
AZSP09_13940	COG1862	Preprotein translocase
AZSP09_13950	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AZSP09_13960	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AZSP09_13980	COG3909	cytochrome
AZSP09_14010	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AZSP09_14020	COG0625	glutathione transferase activity
AZSP09_14030	COG2204	response regulator
AZSP09_14050	COG2204	response regulator
AZSP09_14060	COG0482	sulfurtransferase activity
AZSP09_14110	COG0859	PFAM glycosyl transferase family 9
AZSP09_14130	COG0429	hydrolase of the alpha beta-hydrolase fold
AZSP09_14150	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AZSP09_14160	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AZSP09_14210	COG1858	cytochrome C peroxidase
AZSP09_14220	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AZSP09_14230	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AZSP09_14250	COG0584	glycerophosphoryl diester phosphodiesterase
AZSP09_14280	COG1960	acyl-CoA dehydrogenase activity
AZSP09_14300	COG1988	membrane-bound metal-dependent
AZSP09_14310	COG0667	Aldo Keto reductase
AZSP09_14330	COG1283	sodium-dependent phosphate transmembrane transporter activity
AZSP09_14370	COG0436	Aminotransferase
AZSP09_14400	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AZSP09_14410	COG0235	Class ii aldolase
AZSP09_14440	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AZSP09_14470	COG4566	intracellular signal transduction
AZSP09_14480	COG4191	Histidine kinase
AZSP09_14500	COG1024	Enoyl-CoA hydratase
AZSP09_14530	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AZSP09_14570	COG2814	Major facilitator Superfamily
AZSP09_14620	COG0312	modulator of DNA gyrase
AZSP09_14630	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AZSP09_14650	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AZSP09_14680	COG0513	Belongs to the DEAD box helicase family
AZSP09_14720	COG0631	protein serine/threonine phosphatase activity
AZSP09_14750	COG0247	lactate metabolic process
AZSP09_14760	COG0277	FAD linked oxidase domain protein
AZSP09_14770	COG0277	FAD linked oxidase domain protein
AZSP09_14800	COG0730	response to heat
AZSP09_14840	COG2703	oxygen carrier activity
AZSP09_14850	COG3622	Belongs to the hyi family
AZSP09_14860	COG2096	Adenosyltransferase
AZSP09_14870	COG0251	oxidation-reduction process
AZSP09_14880	COG0583	DNA-binding transcription factor activity
AZSP09_14890	COG1335	isochorismatase
AZSP09_14960	COG3811	Belongs to the UPF0386 family
AZSP09_14980	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AZSP09_15030	COG2084	Dehydrogenase
AZSP09_15050	COG2084	Dehydrogenase
AZSP09_15090	COG0446	pyridine nucleotide-disulphide oxidoreductase
AZSP09_15100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZSP09_15110	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AZSP09_15140	COG0642	Histidine kinase
AZSP09_15150	COG0745	RESPONSE REGULATOR receiver
AZSP09_15170	COG0427	acetyl-CoA hydrolase
AZSP09_15180	COG2223	nitrite transmembrane transporter activity
AZSP09_15190	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AZSP09_15220	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AZSP09_15240	COG3158	transport of potassium into the cell
AZSP09_15250	COG0850	regulation of cytokinetic process
AZSP09_15270	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AZSP09_15310	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZSP09_15320	COG1116	anion transmembrane transporter activity
AZSP09_15350	COG2204	response regulator
AZSP09_15370	COG2197	response regulator
AZSP09_15400	COG0745	RESPONSE REGULATOR receiver
AZSP09_15430	COG0840	transmembrane signaling receptor activity
AZSP09_15440	COG0835	chemotaxis
AZSP09_15470	COG0629	single-stranded DNA binding
AZSP09_15480	COG2814	Major facilitator Superfamily
AZSP09_15490	COG1027	Aspartate ammonia-lyase
AZSP09_15500	COG1301	dicarboxylic acid transport
AZSP09_15620	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AZSP09_15630	COG1047	Peptidyl-prolyl cis-trans
AZSP09_15640	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AZSP09_15650	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AZSP09_15660	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AZSP09_15670	COG0196	riboflavin kinase activity
AZSP09_15680	COG0860	N-Acetylmuramoyl-L-alanine amidase
AZSP09_15690	COG0802	atpase or kinase
AZSP09_15760	COG1722	exodeoxyribonuclease VII activity
AZSP09_15770	COG0142	geranyltranstransferase activity
AZSP09_15780	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AZSP09_15790	COG1469	GTP cyclohydrolase I activity
AZSP09_15800	COG0335	large ribosomal subunit rRNA binding
AZSP09_15810	COG0336	Belongs to the RNA methyltransferase TrmD family
AZSP09_15820	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AZSP09_15830	COG0228	four-way junction DNA binding
AZSP09_15990	COG1295	ribonuclease BN
AZSP09_16010	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AZSP09_16050	COG0745	RESPONSE REGULATOR receiver
AZSP09_16070	COG1183	phosphatidylcholine synthase activity
AZSP09_16080	COG0688	phosphatidylethanolamine metabolic process
AZSP09_16090	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AZSP09_16100	COG0440	acetolactate synthase activity
AZSP09_16110	COG0028	Belongs to the TPP enzyme family
AZSP09_16170	COG0795	lipopolysaccharide-transporting ATPase activity
AZSP09_16180	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AZSP09_16210	COG0525	valine-tRNA ligase activity
AZSP09_16230	COG0425	Belongs to the sulfur carrier protein TusA family
AZSP09_16240	COG4783	chaperone-mediated protein folding
AZSP09_16250	COG0315	cyclic pyranopterin monophosphate synthase activity
AZSP09_16280	COG1278	Cold shock
AZSP09_16290	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AZSP09_16300	COG0542	response to heat
AZSP09_16310	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AZSP09_16320	COG2224	Isocitrate lyase
AZSP09_16350	COG2860	membrane
AZSP09_16370	COG0583	DNA-binding transcription factor activity
AZSP09_16390	COG0730	response to heat
AZSP09_16400	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AZSP09_16450	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AZSP09_16480	COG1253	flavin adenine dinucleotide binding
AZSP09_16490	COG1380	Effector of murein hydrolase LrgA
AZSP09_16500	COG1346	cytolysis
AZSP09_16530	COG2076	Multidrug Resistance protein
AZSP09_16540	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AZSP09_16550	COG0501	Belongs to the peptidase M48B family
AZSP09_16590	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AZSP09_16600	COG0537	adenosine 5'-monophosphoramidase activity
AZSP09_16610	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AZSP09_16620	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AZSP09_16660	COG0708	Exodeoxyribonuclease III
AZSP09_16680	COG0339	signal peptide processing
AZSP09_16700	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AZSP09_16730	COG0778	Nitroreductase
AZSP09_16760	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AZSP09_16790	COG0840	transmembrane signaling receptor activity
AZSP09_16800	COG0009	L-threonylcarbamoyladenylate synthase
AZSP09_16810	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AZSP09_16830	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AZSP09_16890	COG2823	Periplasmic or secreted lipoprotein
AZSP09_16900	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AZSP09_16910	COG0322	excinuclease ABC activity
AZSP09_16960	COG2833	Protein of unknown function (DUF455)
AZSP09_17010	COG0745	RESPONSE REGULATOR receiver
AZSP09_17010	COG2972	Histidine kinase
AZSP09_17020	COG0165	Argininosuccinate lyase
AZSP09_17030	COG2815	serine threonine protein kinase
AZSP09_17030	COG0515	serine threonine protein kinase
AZSP09_17050	COG0004	ammonium transporteR
AZSP09_17090	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AZSP09_17100	COG2890	protein-(glutamine-N5) methyltransferase activity
AZSP09_17110	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AZSP09_17120	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AZSP09_17130	COG1490	D-aminoacyl-tRNA deacylase activity
AZSP09_17150	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AZSP09_17160	COG1012	belongs to the aldehyde dehydrogenase family
AZSP09_17170	COG1139	Iron-sulfur cluster binding protein
AZSP09_17210	COG0280	phosphate acetyltransferase
AZSP09_17210	COG0281	malic enzyme
AZSP09_17230	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AZSP09_17240	COG0436	Aminotransferase
AZSP09_17300	COG0142	geranyltranstransferase activity
AZSP09_17310	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AZSP09_17320	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AZSP09_17330	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AZSP09_17340	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AZSP09_17360	COG0134	indole-3-glycerol-phosphate synthase activity
AZSP09_17370	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AZSP09_17400	COG0546	phosphoglycolate phosphatase activity
AZSP09_17420	COG2967	ApaG domain
AZSP09_17430	COG2226	methyltransferase
AZSP09_17460	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AZSP09_17470	COG0653	protein targeting
AZSP09_17480	COG0739	heme binding
AZSP09_17510	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AZSP09_17520	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AZSP09_17540	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AZSP09_17550	COG1181	Belongs to the D-alanine--D-alanine ligase family
AZSP09_17560	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AZSP09_17570	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AZSP09_17580	COG0772	Belongs to the SEDS family
AZSP09_17590	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AZSP09_17600	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AZSP09_17610	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AZSP09_17620	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AZSP09_17640	COG3116	cell division
AZSP09_17650	COG0275	rRNA processing
AZSP09_17660	COG2001	Belongs to the MraZ family
AZSP09_17700	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AZSP09_17710	COG0792	nuclease activity
AZSP09_17730	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AZSP09_17760	COG1469	GTP cyclohydrolase I activity
AZSP09_17770	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AZSP09_17780	COG4208	sulfate ABC transporter
AZSP09_17800	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AZSP09_17820	COG1858	cytochrome C peroxidase
AZSP09_17830	COG2963	transposase activity
AZSP09_17850	COG0438	transferase activity, transferring glycosyl groups
AZSP09_17860	COG0367	asparagine synthase
AZSP09_17870	COG0367	asparagine synthase
AZSP09_17900	COG0438	transferase activity, transferring glycosyl groups
AZSP09_17990	COG3415	Transposase
AZSP09_17990	COG2801	Transposase and inactivated derivatives
AZSP09_18020	COG0642	Histidine kinase
AZSP09_18040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZSP09_18050	COG0842	Transport permease protein
AZSP09_18050	COG1129	ABC transporter
AZSP09_18060	COG0842	Transport permease protein
AZSP09_18080	COG0745	RESPONSE REGULATOR receiver
AZSP09_18090	COG2205	protein histidine kinase activity
AZSP09_18130	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AZSP09_18140	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AZSP09_18150	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AZSP09_18160	COG1671	Belongs to the UPF0178 family
AZSP09_18170	COG0459	protein refolding
AZSP09_18180	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AZSP09_18240	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AZSP09_18370	COG2217	Heavy metal translocating P-type atpase
AZSP09_18390	COG2205	protein histidine kinase activity
AZSP09_18450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZSP09_18460	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AZSP09_18510	COG1815	bacterial-type flagellum-dependent cell motility
AZSP09_18540	COG2963	transposase activity
AZSP09_18570	COG0024	Methionine aminopeptidase
AZSP09_18610	COG3162	membrane
AZSP09_18660	COG2027	D-alanyl-D-alanine carboxypeptidase
AZSP09_18690	COG1489	DNA binding
AZSP09_18700	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AZSP09_18740	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AZSP09_18750	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AZSP09_18970	COG0477	Major facilitator Superfamily
AZSP09_18980	COG0513	Belongs to the DEAD box helicase family
AZSP09_18990	COG1607	acyl-coa hydrolase
AZSP09_19000	COG0586	Pfam SNARE associated Golgi protein
AZSP09_19010	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AZSP09_19070	COG0183	Belongs to the thiolase family
AZSP09_19080	COG1024	Enoyl-CoA hydratase
AZSP09_19080	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZSP09_19090	COG0318	PFAM AMP-dependent synthetase and ligase
AZSP09_19110	COG2067	long-chain fatty acid transport protein
AZSP09_19120	COG1607	acyl-coa hydrolase
AZSP09_19140	COG1307	EDD domain protein, DegV family
AZSP09_19150	COG0183	Belongs to the thiolase family
AZSP09_19160	COG1960	acyl-CoA dehydrogenase activity
AZSP09_19170	COG1309	transcriptional regulator
AZSP09_19180	COG5265	(ABC) transporter
AZSP09_19190	COG2205	protein histidine kinase activity
AZSP09_19190	COG2202	Pas domain
AZSP09_19220	COG0203	ribosomal protein L17
AZSP09_19230	COG0202	RNA polymerase activity
AZSP09_19240	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AZSP09_19250	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AZSP09_19260	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AZSP09_19270	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AZSP09_19280	COG0201	protein transport
AZSP09_19290	COG0200	Binds to the 23S rRNA
AZSP09_19300	COG1841	ribosomal large subunit assembly
AZSP09_19310	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AZSP09_19320	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AZSP09_19330	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AZSP09_19340	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AZSP09_19350	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AZSP09_19360	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AZSP09_19370	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AZSP09_19390	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AZSP09_19400	COG0255	Belongs to the universal ribosomal protein uL29 family
AZSP09_19410	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AZSP09_19420	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AZSP09_19430	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AZSP09_19440	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AZSP09_19450	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AZSP09_19460	COG0089	rRNA binding
AZSP09_19470	COG0088	Forms part of the polypeptide exit tunnel
AZSP09_19480	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AZSP09_19490	COG0051	transcription antitermination factor activity, RNA binding
AZSP09_19500	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AZSP09_19510	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AZSP09_19520	COG0049	tRNA binding
AZSP09_19530	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AZSP09_19540	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AZSP09_19550	COG0085	RNA polymerase activity
AZSP09_19560	COG0222	ribosome binding
AZSP09_19570	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AZSP09_19580	COG0081	regulation of translation
AZSP09_19590	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AZSP09_19610	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AZSP09_19620	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AZSP09_19630	COG0277	FAD linked oxidase domain protein
AZSP09_19660	COG2205	protein histidine kinase activity
AZSP09_19660	COG2198	Histidine kinase
AZSP09_19660	COG0784	Response regulator, receiver
AZSP09_19690	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AZSP09_19710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AZSP09_19720	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AZSP09_19730	COG0511	ligase activity, forming carbon-carbon bonds
AZSP09_19740	COG0439	Biotin carboxylase
AZSP09_19750	COG2264	protein methyltransferase activity
AZSP09_19830	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AZSP09_19910	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AZSP09_19930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZSP09_19970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZSP09_19980	COG4608	Belongs to the ABC transporter superfamily
AZSP09_20020	COG0385	Bile acid
AZSP09_20050	COG3338	carbonate dehydratase activity
AZSP09_20060	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AZSP09_20070	COG0628	permease
AZSP09_20080	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AZSP09_20100	COG0583	DNA-binding transcription factor activity
AZSP09_20110	COG1902	pentaerythritol trinitrate reductase activity
AZSP09_20120	COG0840	transmembrane signaling receptor activity
AZSP09_20180	COG1530	ribonuclease E activity
AZSP09_20200	COG0412	Dienelactone hydrolase
AZSP09_20210	COG1012	belongs to the aldehyde dehydrogenase family
AZSP09_20220	COG0791	NLP P60 protein
AZSP09_20250	COG2239	Acts as a magnesium transporter
AZSP09_20260	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AZSP09_20270	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AZSP09_20290	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AZSP09_20300	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
AZSP09_20310	COG3150	esterase
AZSP09_20330	COG1968	undecaprenyl-diphosphatase activity
AZSP09_20340	COG0424	maF-like protein
AZSP09_20350	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AZSP09_20360	COG0799	negative regulation of ribosome biogenesis
AZSP09_20370	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AZSP09_20400	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AZSP09_20430	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AZSP09_20430	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AZSP09_20440	COG0859	PFAM glycosyl transferase family 9
AZSP09_20480	COG0438	transferase activity, transferring glycosyl groups
AZSP09_20510	COG0726	polysaccharide deacetylase
AZSP09_20520	COG0438	transferase activity, transferring glycosyl groups
AZSP09_20530	COG1132	(ABC) transporter
AZSP09_20540	COG0438	transferase activity, transferring glycosyl groups
AZSP09_20550	COG0859	PFAM glycosyl transferase family 9
AZSP09_20570	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AZSP09_20580	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AZSP09_20620	COG0602	queuosine metabolic process
AZSP09_20650	COG0823	Involved in the tonB-independent uptake of proteins
AZSP09_20690	COG0824	Thioesterase
AZSP09_20700	COG2255	four-way junction helicase activity
AZSP09_20710	COG0632	four-way junction helicase activity
AZSP09_20720	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AZSP09_20750	COG0217	transcriptional regulatory protein
AZSP09_20760	COG0433	COG0433 Predicted ATPase
AZSP09_20790	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AZSP09_20810	COG0129	dihydroxy-acid dehydratase activity
AZSP09_20830	COG1999	signal sequence binding
AZSP09_20840	COG0386	Belongs to the glutathione peroxidase family
AZSP09_20860	COG2703	oxygen carrier activity
AZSP09_20870	COG0840	transmembrane signaling receptor activity
AZSP09_20880	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AZSP09_20930	COG0559	Belongs to the binding-protein-dependent transport system permease family
AZSP09_20950	COG1022	Amp-dependent synthetase and ligase
AZSP09_20980	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AZSP09_20980	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AZSP09_20980	COG1703	isobutyryl-CoA mutase activity
AZSP09_21020	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AZSP09_21040	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AZSP09_21070	COG0067	glutamate synthase
AZSP09_21070	COG0069	glutamate synthase activity
AZSP09_21070	COG0070	glutamate synthase
AZSP09_21080	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AZSP09_21090	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AZSP09_21110	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AZSP09_21120	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AZSP09_21130	COG0840	transmembrane signaling receptor activity
AZSP09_21140	COG0004	ammonium transporteR
AZSP09_21150	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AZSP09_21170	COG0352	thiamine-phosphate diphosphorylase activity
AZSP09_21180	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AZSP09_21190	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AZSP09_21200	COG0237	dephospho-CoA kinase activity
AZSP09_21220	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
AZSP09_21230	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AZSP09_21240	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AZSP09_21240	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AZSP09_21250	COG2204	response regulator
AZSP09_21260	COG3852	Histidine kinase
AZSP09_21330	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AZSP09_21350	COG3568	Endonuclease Exonuclease Phosphatase
AZSP09_21360	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AZSP09_21370	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AZSP09_21380	COG0012	GTP binding
AZSP09_21390	COG0193	aminoacyl-tRNA hydrolase activity
AZSP09_21400	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AZSP09_21410	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AZSP09_21420	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AZSP09_21450	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AZSP09_21460	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AZSP09_21470	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AZSP09_21480	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AZSP09_21490	COG0742	ribosomal rna small subunit methyltransferase
AZSP09_21500	COG0612	Peptidase, M16
AZSP09_21510	COG0612	Peptidase, M16
AZSP09_21530	COG2884	Cell division ATP-binding protein ftsE
AZSP09_21540	COG2177	Part of the ABC transporter FtsEX involved in
AZSP09_21550	COG0415	Belongs to the DNA photolyase family
AZSP09_21570	COG1678	Uncharacterized ACR, COG1678
AZSP09_21580	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AZSP09_21590	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AZSP09_21600	COG0540	Belongs to the ATCase OTCase family
AZSP09_21630	COG3279	Response regulator of the LytR AlgR family
AZSP09_21640	COG1872	DUF167
AZSP09_21650	COG0762	integral membrane protein
AZSP09_21740	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AZSP09_21750	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AZSP09_21800	COG0577	efflux transmembrane transporter activity
AZSP09_21800	COG1136	(ABC) transporter
AZSP09_21850	COG1595	DNA-templated transcription, initiation
AZSP09_21890	COG2151	metal-sulfur cluster biosynthetic enzyme
AZSP09_21950	COG4654	Cytochrome c, class I
AZSP09_21960	COG1331	Highly conserved protein containing a thioredoxin domain
AZSP09_21970	COG0583	DNA-binding transcription factor activity
AZSP09_21980	COG0697	spore germination
AZSP09_22000	COG0765	amino acid transport
AZSP09_22010	COG0765	amino acid transport
AZSP09_22020	COG1126	abc transporter atp-binding protein
AZSP09_22040	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AZSP09_22060	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AZSP09_22080	COG0318	PFAM AMP-dependent synthetase and ligase
AZSP09_22090	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AZSP09_22110	COG1560	Kdo2-lipid A biosynthetic process
AZSP09_22130	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AZSP09_22160	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AZSP09_22200	COG3647	Membrane
AZSP09_22210	COG2198	Histidine kinase
AZSP09_22210	COG0643	Histidine kinase
AZSP09_22270	COG0351	phosphomethylpyrimidine kinase
AZSP09_22280	COG0352	thiamine-phosphate diphosphorylase activity
AZSP09_22290	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AZSP09_22300	COG3152	Membrane
AZSP09_22310	COG2326	polyphosphate kinase activity
AZSP09_22400	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AZSP09_22410	COG0018	arginyl-trna synthetase
AZSP09_22430	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AZSP09_22470	COG1999	signal sequence binding
AZSP09_22490	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AZSP09_22500	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AZSP09_22510	COG0741	lytic transglycosylase activity
AZSP09_22540	COG0617	tRNA 3'-terminal CCA addition
AZSP09_22560	COG0625	glutathione transferase activity
AZSP09_22630	COG0037	tRNA processing
AZSP09_22640	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AZSP09_22650	COG2815	serine threonine protein kinase
AZSP09_22650	COG0515	serine threonine protein kinase
AZSP09_22700	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AZSP09_22720	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AZSP09_22730	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AZSP09_22740	COG1137	ATPase activity
AZSP09_22750	COG2137	regulation of response to DNA damage stimulus
AZSP09_22760	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AZSP09_22780	COG2193	ferroxidase activity
AZSP09_22790	COG1546	Belongs to the CinA family
AZSP09_22800	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AZSP09_22820	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AZSP09_22830	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AZSP09_22860	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AZSP09_22870	COG4232	protein-disulfide reductase activity
AZSP09_22930	COG1131	(ABC) transporter
AZSP09_22950	COG3411	Ferredoxin
AZSP09_22970	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AZSP09_22980	COG1238	metal cluster binding
AZSP09_23010	COG0432	Pfam Uncharacterised protein family UPF0047
AZSP09_23020	COG2223	nitrite transmembrane transporter activity
AZSP09_23030	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AZSP09_23030	COG2813	Specifically methylates the guanine in position
AZSP09_23040	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AZSP09_23050	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AZSP09_23060	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AZSP09_23090	COG0189	ligase activity
AZSP09_23170	COG0488	(ABC) transporter
AZSP09_23200	COG0488	(ABC) transporter
AZSP09_23220	COG5002	protein histidine kinase activity
AZSP09_23220	COG5001	Diguanylate cyclase
AZSP09_23250	COG0004	ammonium transporteR
AZSP09_23280	COG2960	long-chain fatty acid transporting porin activity
AZSP09_23300	COG2814	Major facilitator Superfamily
AZSP09_23330	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AZSP09_23350	COG1028	Short-chain dehydrogenase reductase Sdr
AZSP09_23370	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AZSP09_23390	COG3876	Protein conserved in bacteria
AZSP09_23440	COG2203	Gaf domain
AZSP09_23440	COG4251	negative regulation of phosphorylation
AZSP09_23440	COG5001	Diguanylate cyclase
AZSP09_23440	COG3706	GGDEF domain
AZSP09_23450	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AZSP09_23530	COG0288	reversible hydration of carbon dioxide
AZSP09_23560	COG1940	carbohydrate kinase activity
AZSP09_23570	COG2258	MOSC domain
AZSP09_23600	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AZSP09_23620	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AZSP09_23640	COG0569	domain protein
AZSP09_23650	COG2204	response regulator
AZSP09_23680	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AZSP09_23680	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AZSP09_23690	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AZSP09_23710	COG0501	Belongs to the peptidase M48B family
AZSP09_23720	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AZSP09_23730	COG0242	peptide deformylase activity
AZSP09_23750	COG0758	DNA mediated transformation
AZSP09_23760	COG2922	Belongs to the Smg family
AZSP09_23780	COG0783	Belongs to the Dps family
AZSP09_23790	COG0583	DNA-binding transcription factor activity
AZSP09_23800	COG1187	pseudouridine synthase activity
AZSP09_23830	COG2755	lipolytic protein G-D-S-L family
AZSP09_23830	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AZSP09_23850	COG3586	endonuclease activity
AZSP09_23890	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AZSP09_23920	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AZSP09_23930	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AZSP09_23940	COG0594	ribonuclease P activity
AZSP09_23950	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AZSP09_23960	COG0706	membrane insertase activity
AZSP09_23970	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AZSP09_24020	COG0411	ABC transporter
AZSP09_24060	COG0445	tRNA wobble uridine modification
AZSP09_24070	COG0357	Ribosomal RNA small subunit methyltransferase G
AZSP09_24080	COG1192	Involved in chromosome partitioning
AZSP09_24090	COG1475	DNA binding
AZSP09_24110	COG0356	it plays a direct role in the translocation of protons across the membrane
AZSP09_24130	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AZSP09_24140	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AZSP09_24150	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AZSP09_24160	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AZSP09_24170	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AZSP09_24180	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AZSP09_24230	COG0745	RESPONSE REGULATOR receiver
AZSP09_24240	COG5002	protein histidine kinase activity
AZSP09_24320	COG0708	Exodeoxyribonuclease III
AZSP09_24330	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AZSP09_24370	COG0348	domain, Protein
AZSP09_24430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZSP09_24440	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AZSP09_24460	COG0154	amidase activity
AZSP09_24470	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AZSP09_24480	COG1077	Cell shape determining protein MreB Mrl
AZSP09_24490	COG1792	Involved in formation and maintenance of cell shape
AZSP09_24500	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AZSP09_24510	COG0768	penicillin binding
AZSP09_24520	COG0772	Belongs to the SEDS family
AZSP09_24590	COG1686	Belongs to the peptidase S11 family
AZSP09_24600	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AZSP09_24610	COG2921	Belongs to the UPF0250 family
AZSP09_24620	COG0321	lipoyl(octanoyl) transferase activity
AZSP09_24630	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AZSP09_24720	COG2129	metallophosphoesterase
AZSP09_24820	COG3437	response regulator, receiver
AZSP09_24840	COG5002	protein histidine kinase activity
AZSP09_24840	COG2205	protein histidine kinase activity
AZSP09_24840	COG0784	Response regulator, receiver
AZSP09_24890	COG0114	fumarate hydratase activity
AZSP09_24910	COG0348	domain, Protein
AZSP09_24930	COG2204	response regulator
AZSP09_24960	COG0210	DNA helicase
AZSP09_24980	COG3245	cytochrome
AZSP09_25010	COG3706	GGDEF domain
AZSP09_25010	COG0745	RESPONSE REGULATOR receiver
AZSP09_25060	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AZSP09_25080	COG5554	nitrogen fixation
AZSP09_25120	COG2030	dehydratase
AZSP09_25130	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AZSP09_25170	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
AZSP09_25190	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AZSP09_25290	COG1515	deoxyribonuclease V activity
AZSP09_25310	COG3706	GGDEF domain
AZSP09_25310	COG0745	RESPONSE REGULATOR receiver
AZSP09_25320	COG3243	poly(R)-hydroxyalkanoic acid synthase
AZSP09_25360	COG1960	acyl-CoA dehydrogenase activity
AZSP09_25370	COG0183	Belongs to the thiolase family
AZSP09_25380	COG1960	acyl-CoA dehydrogenase activity
AZSP09_25400	COG1408	metallophosphoesterase
AZSP09_25420	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AZSP09_25430	COG1024	Enoyl-CoA hydratase
AZSP09_25450	COG5001	Diguanylate cyclase
AZSP09_25470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZSP09_25490	COG1473	amidohydrolase
AZSP09_25500	COG1660	Displays ATPase and GTPase activities
AZSP09_25560	COG0741	lytic transglycosylase activity
AZSP09_25580	COG1194	a g-specific adenine glycosylase
AZSP09_25590	COG0714	Associated with various cellular activities
AZSP09_25630	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AZSP09_25640	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AZSP09_25670	COG0582	viral genome integration into host DNA
AZSP09_25800	COG2003	Belongs to the UPF0758 family
AZSP09_25920	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AZSP09_25980	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AZSP09_26210	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AZSP09_26300	COG1192	Involved in chromosome partitioning
AZSP09_26330	COG0583	DNA-binding transcription factor activity
AZSP09_26360	COG0071	Belongs to the small heat shock protein (HSP20) family
AZSP09_26370	COG0542	response to heat
AZSP09_26390	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AZSP09_26430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AZSP09_26440	COG0583	DNA-binding transcription factor activity
AZSP09_26450	COG0583	DNA-binding transcription factor activity
AZSP09_26530	COG2022	thiamine diphosphate biosynthetic process
AZSP09_26550	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AZSP09_26590	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AZSP09_26600	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AZSP09_26630	COG1121	(ABC) transporter
AZSP09_26640	COG0803	Belongs to the bacterial solute-binding protein 9 family
AZSP09_26670	COG0523	cobalamin synthesis protein
AZSP09_26680	COG0523	cobalamin synthesis protein
AZSP09_26770	COG3411	Ferredoxin
AZSP09_26800	COG5001	Diguanylate cyclase
AZSP09_26800	COG3447	MASE1 domain protein
AZSP09_26800	COG5002	protein histidine kinase activity
AZSP09_26930	COG2824	Alkylphosphonate utilization operon protein PhnA
AZSP09_26960	COG4231	catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
AZSP09_26980	COG5420	small protein containing a coiled-coil domain
AZSP09_27010	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AZSP09_27020	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AZSP09_27030	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AZSP09_27040	COG2391	methyltransferase activity
AZSP09_27070	COG1492	cobalamin metabolic process
AZSP09_27100	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AZSP09_27160	COG1797	cobyrinic acid a,c-diamide synthase activity
AZSP09_27180	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AZSP09_27190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AZSP09_27200	COG4774	siderophore transport
AZSP09_27240	COG0730	response to heat
AZSP09_27250	COG3162	membrane
AZSP09_27260	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AZSP09_27270	COG1024	Enoyl-CoA hydratase
AZSP09_27280	COG1802	Transcriptional regulator
AZSP09_27290	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AZSP09_27290	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AZSP09_27300	COG1703	isobutyryl-CoA mutase activity
AZSP09_27310	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AZSP09_27320	COG0439	Biotin carboxylase
AZSP09_27370	COG2129	metallophosphoesterase
AZSP09_27400	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AZSP09_27500	COG0348	domain, Protein
AZSP09_27510	COG0437	4 iron, 4 sulfur cluster binding
AZSP09_27520	COG0243	molybdopterin cofactor binding
AZSP09_27550	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AZSP09_27550	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AZSP09_27560	COG3781	membrane
AZSP09_27570	COG0084	hydrolase, TatD family'
AZSP09_27580	COG1024	Enoyl-CoA hydratase
AZSP09_27590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZSP09_27600	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AZSP09_27610	COG1758	RNA polymerase activity
AZSP09_27620	COG0194	GDP metabolic process
AZSP09_27630	COG1561	YicC-like family, N-terminal region
AZSP09_27640	COG2815	serine threonine protein kinase
AZSP09_27640	COG0515	serine threonine protein kinase
AZSP09_27660	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AZSP09_27680	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AZSP09_27690	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AZSP09_27790	COG2814	Major facilitator Superfamily
AZSP09_27920	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AZSP09_27930	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AZSP09_27940	COG4191	Histidine kinase
AZSP09_27960	COG0501	Belongs to the peptidase M48B family
AZSP09_27980	COG0583	DNA-binding transcription factor activity
AZSP09_28010	COG2204	response regulator
AZSP09_28020	COG1024	Enoyl-CoA hydratase
AZSP09_28020	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AZSP09_28050	COG0309	Hydrogenase expression formation protein (HypE)
AZSP09_28060	COG0409	Hydrogenase expression formation protein
AZSP09_28070	COG0298	carbon dioxide binding
AZSP09_28090	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AZSP09_28120	COG0375	protein maturation
AZSP09_28140	COG1858	cytochrome C peroxidase
AZSP09_28150	COG4133	protoheme IX ABC transporter activity
AZSP09_28160	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AZSP09_28180	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AZSP09_28190	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AZSP09_28210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AZSP09_28280	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AZSP09_28290	COG4191	Histidine kinase
AZSP09_28300	COG0019	diaminopimelate decarboxylase activity
AZSP09_28320	COG1965	Belongs to the frataxin family
AZSP09_28330	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AZSP09_28360	COG1484	DNA-dependent DNA replication
AZSP09_28370	COG4584	PFAM Integrase catalytic
AZSP09_28400	COG3039	Transposase
AZSP09_28410	COG4585	Histidine kinase
AZSP09_28420	COG2197	response regulator
AZSP09_28430	COG0318	PFAM AMP-dependent synthetase and ligase
AZSP09_28450	COG1024	Enoyl-CoA hydratase
AZSP09_28450	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZSP09_28460	COG0183	Belongs to the thiolase family
AZSP09_28470	COG1960	acyl-CoA dehydrogenase activity
AZSP09_28510	COG2030	dehydratase
AZSP09_28580	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AZSP09_28590	COG1702	phosphate starvation-inducible protein PhoH
AZSP09_28600	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AZSP09_28610	COG4535	Mg2 and Co2 transporter CorC
AZSP09_28620	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AZSP09_28630	COG0752	glycyl-tRNA synthetase alpha subunit
AZSP09_28640	COG0751	glycine-tRNA ligase activity
AZSP09_28650	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AZSP09_28810	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AZSP09_28840	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AZSP09_28850	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AZSP09_28870	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AZSP09_28900	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AZSP09_28910	COG4974	Belongs to the 'phage' integrase family
AZSP09_28940	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AZSP09_28960	COG1466	dna polymerase III delta subunit
AZSP09_28980	COG0495	leucyl-tRNA aminoacylation
AZSP09_29010	COG0210	DNA helicase
AZSP09_29060	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AZSP09_29070	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AZSP09_29080	COG0312	modulator of DNA gyrase
AZSP09_29090	COG3028	Belongs to the UPF0307 family
AZSP09_29100	COG0521	Mo-molybdopterin cofactor biosynthetic process
AZSP09_29120	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AZSP09_29130	COG0166	Belongs to the GPI family
AZSP09_29150	COG1982	Orn Lys Arg decarboxylase major
AZSP09_29160	COG0717	Belongs to the dCTP deaminase family
AZSP09_29170	COG0489	protein tyrosine kinase activity
AZSP09_29180	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AZSP09_29180	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AZSP09_29200	COG0659	secondary active sulfate transmembrane transporter activity
AZSP09_29210	COG1254	Belongs to the acylphosphatase family
AZSP09_29230	COG0450	alkyl hydroperoxide reductase
AZSP09_29240	COG4771	TonB-dependent receptor
AZSP09_29310	COG0463	Glycosyl transferase, family 2
AZSP09_29330	COG0583	DNA-binding transcription factor activity
AZSP09_29340	COG1741	Belongs to the pirin family
AZSP09_29360	COG0745	RESPONSE REGULATOR receiver
AZSP09_29400	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AZSP09_29410	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AZSP09_29420	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AZSP09_29420	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AZSP09_29430	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AZSP09_29450	COG0793	Belongs to the peptidase S41A family
AZSP09_29460	COG4942	peptidase
AZSP09_29470	COG0640	Transcriptional regulator
AZSP09_29480	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AZSP09_29500	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AZSP09_29520	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AZSP09_29530	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AZSP09_29540	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AZSP09_29680	COG1450	Type ii and iii secretion system protein
AZSP09_29690	COG3267	Type II secretory pathway component ExeA
AZSP09_29690	COG3409	Peptidoglycan-binding domain 1 protein
AZSP09_29710	COG3307	-O-antigen
AZSP09_29730	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AZSP09_29740	COG2226	methyltransferase
AZSP09_29750	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AZSP09_29760	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AZSP09_29810	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AZSP09_29850	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AZSP09_29860	COG0071	Belongs to the small heat shock protein (HSP20) family
AZSP09_29880	COG0494	nUDIX hydrolase
AZSP09_29890	COG2732	(Barnase) inhibitor
AZSP09_29910	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AZSP09_29940	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AZSP09_29970	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AZSP09_29980	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AZSP09_29990	COG0741	lytic transglycosylase activity
AZSP09_30000	COG0442	prolyl-tRNA aminoacylation
AZSP09_30010	COG0494	nUDIX hydrolase
AZSP09_30040	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
AZSP09_30050	COG1765	OsmC-like protein
AZSP09_30060	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AZSP09_30070	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AZSP09_30100	COG0316	Belongs to the HesB IscA family
AZSP09_30110	COG1388	LysM domain
AZSP09_30110	COG4942	peptidase
AZSP09_30120	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AZSP09_30140	COG0596	Alpha beta hydrolase
AZSP09_30160	COG0598	Magnesium transport protein CorA
AZSP09_30170	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AZSP09_30190	COG2703	oxygen carrier activity
AZSP09_30220	COG0513	Belongs to the DEAD box helicase family
AZSP09_30230	COG2030	dehydratase
AZSP09_30250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZSP09_30290	COG0739	heme binding
AZSP09_30310	COG0284	orotidine-5'-phosphate decarboxylase activity
AZSP09_30330	COG5001	Diguanylate cyclase
AZSP09_30330	COG3447	MASE1 domain protein
AZSP09_30330	COG5002	protein histidine kinase activity
AZSP09_30380	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AZSP09_30390	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AZSP09_30410	COG0583	DNA-binding transcription factor activity
AZSP09_30420	COG0840	transmembrane signaling receptor activity
AZSP09_30430	COG1643	Atp-dependent helicase
AZSP09_30480	COG1024	Enoyl-CoA hydratase
AZSP09_30490	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AZSP09_30510	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AZSP09_30660	COG3267	Type II secretory pathway component ExeA
AZSP09_30660	COG3409	Peptidoglycan-binding domain 1 protein
AZSP09_30670	COG2204	response regulator
AZSP09_30680	COG1127	ABC transporter
AZSP09_30690	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AZSP09_30700	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AZSP09_30710	COG2853	Lipoprotein
AZSP09_30730	COG3113	response to antibiotic
AZSP09_30740	COG1131	(ABC) transporter
AZSP09_30750	COG0842	Transport permease protein
AZSP09_30760	COG5007	Belongs to the BolA IbaG family
AZSP09_30770	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AZSP09_30800	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AZSP09_30810	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AZSP09_30840	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AZSP09_30850	COG0131	Imidazoleglycerol-phosphate dehydratase
AZSP09_30860	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AZSP09_30870	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AZSP09_30880	COG0107	imidazoleglycerol-phosphate synthase activity
AZSP09_30890	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AZSP09_30900	COG0140	phosphoribosyl-ATP diphosphatase activity
AZSP09_30920	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AZSP09_30930	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AZSP09_30950	COG0121	glutamine amidotransferase
AZSP09_30960	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AZSP09_30970	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AZSP09_31000	COG5001	Diguanylate cyclase
AZSP09_31000	COG4251	negative regulation of phosphorylation
AZSP09_31000	COG3706	GGDEF domain
AZSP09_31000	COG2203	Gaf domain
AZSP09_31020	COG2201	protein-glutamate methylesterase activity
AZSP09_31030	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AZSP09_31040	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AZSP09_31050	COG0835	chemotaxis
AZSP09_31060	COG0840	transmembrane signaling receptor activity
AZSP09_31070	COG2198	Histidine kinase
AZSP09_31070	COG0643	Histidine kinase
AZSP09_31120	COG0534	Mate efflux family protein
AZSP09_31150	COG0045	succinate-CoA ligase (ADP-forming) activity
AZSP09_31160	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AZSP09_31170	COG0861	Integral membrane protein TerC family
AZSP09_31190	COG0515	serine threonine protein kinase
AZSP09_31190	COG2815	serine threonine protein kinase
AZSP09_31200	COG0631	protein serine/threonine phosphatase activity
AZSP09_31240	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AZSP09_31260	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AZSP09_31310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZSP09_31320	COG1136	(ABC) transporter
AZSP09_31330	COG3284	Transcriptional regulator
AZSP09_31340	COG1012	belongs to the aldehyde dehydrogenase family
AZSP09_31400	COG0577	efflux transmembrane transporter activity
AZSP09_31400	COG1136	(ABC) transporter
AZSP09_31420	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AZSP09_31430	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AZSP09_31440	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AZSP09_31450	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AZSP09_31460	COG0840	transmembrane signaling receptor activity
AZSP09_31570	COG1752	Esterase of the alpha-beta hydrolase superfamily
AZSP09_31610	COG0617	tRNA 3'-terminal CCA addition
AZSP09_31640	COG0628	permease
AZSP09_31660	COG4654	Cytochrome c, class I
AZSP09_31680	COG2815	serine threonine protein kinase
AZSP09_31680	COG0515	serine threonine protein kinase
AZSP09_31690	COG2814	Major facilitator Superfamily
AZSP09_31700	COG1846	Transcriptional regulator
AZSP09_31710	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AZSP09_31740	COG2205	protein histidine kinase activity
AZSP09_31750	COG0745	RESPONSE REGULATOR receiver
AZSP09_31790	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AZSP09_31800	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AZSP09_31810	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AZSP09_31830	COG2003	Belongs to the UPF0758 family
AZSP09_31840	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AZSP09_31850	COG0756	dUTP diphosphatase activity
AZSP09_31860	COG0446	pyridine nucleotide-disulphide oxidoreductase
AZSP09_31880	COG1196	nuclear chromosome segregation
AZSP09_31880	COG3264	Mechanosensitive ion channel
AZSP09_31890	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AZSP09_31890	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AZSP09_31910	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AZSP09_31930	COG0586	Pfam SNARE associated Golgi protein
AZSP09_31940	COG0784	Response regulator, receiver
AZSP09_31950	COG4251	negative regulation of phosphorylation
AZSP09_31960	COG5001	Diguanylate cyclase
AZSP09_31970	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AZSP09_31990	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AZSP09_32020	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AZSP09_32040	COG0126	phosphoglycerate kinase activity
AZSP09_32050	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AZSP09_32070	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AZSP09_32080	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AZSP09_32100	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AZSP09_32120	COG5001	Diguanylate cyclase
AZSP09_32120	COG5002	protein histidine kinase activity
AZSP09_32150	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AZSP09_32170	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AZSP09_32170	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AZSP09_32180	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AZSP09_32200	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AZSP09_32220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AZSP09_32230	COG0508	dehydrogenase complex catalyzes the overall conversion of
AZSP09_32240	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AZSP09_32270	COG4566	intracellular signal transduction
AZSP09_32280	COG0247	lactate metabolic process
AZSP09_32290	COG1139	Iron-sulfur cluster binding protein
AZSP09_32300	COG1556	Lactate utilization protein
AZSP09_32310	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AZSP09_32320	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AZSP09_32330	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AZSP09_32370	COG0006	proline dipeptidase activity
AZSP09_32380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AZSP09_32420	COG0151	Belongs to the GarS family
AZSP09_32430	COG0408	coproporphyrinogen oxidase activity
AZSP09_32460	COG2959	enzyme of heme biosynthesis
AZSP09_32480	COG0181	hydroxymethylbilane synthase activity
AZSP09_32490	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AZSP09_32520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AZSP09_32660	COG0745	RESPONSE REGULATOR receiver
AZSP09_32670	COG0642	Histidine kinase
AZSP09_32680	COG2194	sulfuric ester hydrolase activity
AZSP09_32730	COG2217	Heavy metal translocating P-type atpase
AZSP09_32750	COG3278	Belongs to the heme-copper respiratory oxidase family
AZSP09_32830	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AZSP09_32840	COG3243	poly(R)-hydroxyalkanoic acid synthase
AZSP09_32930	COG3945	hemerythrin HHE cation binding domain
AZSP09_32940	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AZSP09_32950	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AZSP09_32980	COG2217	Heavy metal translocating P-type atpase
AZSP09_33040	COG1918	ferrous iron import across plasma membrane
AZSP09_33040	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AZSP09_33070	COG0672	)-iron permease
AZSP09_33080	COG4633	Protein conserved in bacteria
AZSP09_33240	COG3128	pkhd-type hydroxylase
AZSP09_33250	COG4774	siderophore transport
AZSP09_33270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AZSP09_33280	COG1858	cytochrome C peroxidase
AZSP09_33290	COG4771	TonB-dependent receptor
AZSP09_33350	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AZSP09_33370	COG1429	ligase activity, forming nitrogen-metal bonds
AZSP09_33380	COG4771	TonB-dependent receptor
AZSP09_33440	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AZSP09_33440	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AZSP09_33450	COG0347	Belongs to the P(II) protein family
AZSP09_33460	COG2840	Smr protein MutS2
AZSP09_33470	COG0492	ferredoxin-NADP+ reductase activity
AZSP09_33490	COG1674	ftsk spoiiie
AZSP09_33500	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AZSP09_33530	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AZSP09_33550	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AZSP09_33560	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AZSP09_33650	COG2076	Multidrug Resistance protein
AZSP09_33700	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AZSP09_33710	COG1360	Flagellar Motor Protein
AZSP09_33740	COG2198	Histidine kinase
AZSP09_33740	COG0643	Histidine kinase
AZSP09_33750	COG0835	chemotaxis
AZSP09_33760	COG0840	transmembrane signaling receptor activity
AZSP09_33760	COG0840	transmembrane signaling receptor activity
AZSP09_33770	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AZSP09_33780	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AZSP09_33790	COG2201	protein-glutamate methylesterase activity
AZSP09_33820	COG0840	transmembrane signaling receptor activity
AZSP09_33830	COG0784	Response regulator, receiver
AZSP09_33830	COG0835	chemotaxis
AZSP09_33840	COG0784	Response regulator, receiver
AZSP09_33840	COG0835	chemotaxis
AZSP09_33850	COG0745	RESPONSE REGULATOR receiver
AZSP09_33860	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AZSP09_33870	COG2198	Histidine kinase
AZSP09_33870	COG0643	Histidine kinase
AZSP09_33930	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AZSP09_33990	COG1558	bacterial-type flagellum-dependent cell motility
AZSP09_34000	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AZSP09_34010	COG1749	Flagellar hook protein flgE
AZSP09_34020	COG4787	bacterial-type flagellum-dependent cell motility
AZSP09_34030	COG4786	Flagellar basal body rod
AZSP09_34040	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AZSP09_34050	COG1706	bacterial-type flagellum-dependent cell motility
AZSP09_34110	COG1987	bacterial-type flagellum assembly
AZSP09_34130	COG3190	flagellar
AZSP09_34140	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AZSP09_34150	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AZSP09_34170	COG3144	bacterial-type flagellum assembly
AZSP09_34190	COG1157	protein secretion by the type III secretion system
AZSP09_34210	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AZSP09_34230	COG0784	Response regulator, receiver
AZSP09_34230	COG2205	protein histidine kinase activity
AZSP09_34240	COG2204	response regulator
AZSP09_34250	COG1677	Flagellar hook-basal body complex protein FliE
AZSP09_34260	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
AZSP09_34270	COG2257	FlhB HrpN YscU SpaS Family
AZSP09_34330	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AZSP09_34340	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AZSP09_34370	COG0438	transferase activity, transferring glycosyl groups
AZSP09_34370	COG1216	Glycosyl transferase, family 2
AZSP09_34380	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AZSP09_34440	COG1215	transferase activity, transferring glycosyl groups
AZSP09_34480	COG0022	dehydrogenase e1 component
AZSP09_34490	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AZSP09_34500	COG0859	PFAM glycosyl transferase family 9
AZSP09_34520	COG3706	GGDEF domain
AZSP09_34520	COG0745	RESPONSE REGULATOR receiver
AZSP09_34530	COG0582	viral genome integration into host DNA
AZSP09_34710	COG1309	transcriptional regulator
AZSP09_34740	COG1538	Outer membrane efflux protein
AZSP09_34770	COG2963	transposase activity
AZSP09_34800	COG1414	Transcriptional regulator
AZSP09_34830	COG4804	nuclease activity
AZSP09_35100	COG3800	Transcriptional regulator
AZSP09_35100	COG1396	sequence-specific DNA binding
AZSP09_35140	COG1607	acyl-coa hydrolase
AZSP09_35160	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AZSP09_35170	COG1802	Transcriptional regulator
AZSP09_35180	COG0583	DNA-binding transcription factor activity
AZSP09_35190	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AZSP09_35200	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AZSP09_35240	COG1120	ATPase activity
AZSP09_35250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AZSP09_35260	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AZSP09_35280	COG1607	acyl-coa hydrolase
AZSP09_35290	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AZSP09_35290	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AZSP09_35320	COG0602	queuosine metabolic process
AZSP09_35330	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AZSP09_35350	COG4644	lycopene metabolic process
AZSP09_35400	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AZSP09_35500	COG1674	ftsk spoiiie
AZSP09_35930	COG1674	ftsk spoiiie
AZSP09_36220	COG0592	DNA-directed DNA polymerase activity
AZSP09_36400	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AZSP09_36680	COG1199	ATP-dependent helicase activity
AZSP09_36920	COG4680	protein conserved in bacteria
AZSP09_37360	COG0322	excinuclease ABC activity
AZSP09_37470	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AZSP09_37750	COG0463	Glycosyl transferase, family 2
AZSP09_37760	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AZSP09_38010	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AZSP09_38170	COG4585	Histidine kinase
AZSP09_38220	COG3541	Predicted nucleotidyltransferase
AZSP09_38230	COG4804	nuclease activity
AZSP09_38250	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AZSP09_38330	COG0629	single-stranded DNA binding
AZSP09_38410	COG2894	cell division
AZSP09_38460	COG2974	May be involved in recombination
AZSP09_38570	COG0739	heme binding
AZSP09_38630	COG4316	Uncharacterized protein conserved in bacteria (DUF2251)
AZSP09_38740	COG3451	type IV secretory pathway VirB4
AZSP09_38760	COG3838	Conjugal transfer protein Trbc
AZSP09_38770	COG4962	Type ii secretion system protein e
AZSP09_38810	COG0583	DNA-binding transcription factor activity
AZSP09_38860	COG2076	Multidrug Resistance protein
AZSP09_38890	COG4372	Transposase
AZSP09_38930	COG4959	Type IV secretory pathway protease TraF
AZSP09_38960	COG1192	Involved in chromosome partitioning
AZSP09_39030	COG5489	Protein of unknown function (DUF736)
AZSP09_39070	COG3077	Addiction module antitoxin, RelB DinJ family
AZSP09_39090	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AZSP09_39110	COG1484	DNA-dependent DNA replication
AZSP09_39120	COG4584	PFAM Integrase catalytic
AZSP09_39150	COG3039	Transposase
AZSP09_39160	COG4585	Histidine kinase
AZSP09_39170	COG2197	response regulator
AZSP09_39180	COG0318	PFAM AMP-dependent synthetase and ligase
AZSP09_39200	COG1024	Enoyl-CoA hydratase
AZSP09_39200	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZSP09_39210	COG0183	Belongs to the thiolase family
AZSP09_39220	COG1960	acyl-CoA dehydrogenase activity
AZSP09_39260	COG2030	dehydratase