locus-tag	class	description
H1Q64_00025	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
H1Q64_00030	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
H1Q64_00035	COG0295	cytidine deaminase activity
H1Q64_00040	COG1079	Belongs to the binding-protein-dependent transport system permease family
H1Q64_00045	COG4603	Belongs to the binding-protein-dependent transport system permease family
H1Q64_00050	COG3845	ABC transporter
H1Q64_00055	COG1744	ABC transporter substrate-binding protein PnrA-like
H1Q64_00075	COG0768	penicillin binding
H1Q64_00095	COG2862	Uncharacterized protein family, UPF0114
H1Q64_00100	COG0704	Plays a role in the regulation of phosphate uptake
H1Q64_00115	COG0028	Belongs to the TPP enzyme family
H1Q64_00120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1Q64_00125	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
H1Q64_00150	COG0330	HflC and HflK could
H1Q64_00155	COG0330	HflC and HflK could
H1Q64_00160	COG0489	protein tyrosine kinase activity
H1Q64_00175	COG4120	Belongs to the binding-protein-dependent transport system permease family
H1Q64_00200	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
H1Q64_00215	COG3070	regulator of competence-specific genes
H1Q64_00225	COG0242	peptide deformylase activity
H1Q64_00230	COG0828	Belongs to the bacterial ribosomal protein bS21 family
H1Q64_00235	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
H1Q64_00365	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H1Q64_00370	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
H1Q64_00375	COG0343	queuine tRNA-ribosyltransferase activity
H1Q64_00380	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
H1Q64_00385	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H1Q64_00405	COG0840	transmembrane signaling receptor activity
H1Q64_00415	COG0318	PFAM AMP-dependent synthetase and ligase
H1Q64_00435	COG2960	long-chain fatty acid transporting porin activity
H1Q64_00460	COG3321	synthase
H1Q64_00460	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q64_00460	COG0604	alcohol dehydrogenase
H1Q64_00475	COG0288	reversible hydration of carbon dioxide
H1Q64_00505	COG0205	6-phosphofructokinase activity
H1Q64_00520	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H1Q64_00525	COG5001	Diguanylate cyclase
H1Q64_00525	COG5002	protein histidine kinase activity
H1Q64_00545	COG0114	fumarate hydratase activity
H1Q64_00595	COG1454	alcohol dehydrogenase
H1Q64_00615	COG2951	lytic endotransglycosylase activity
H1Q64_00625	COG0432	Pfam Uncharacterised protein family UPF0047
H1Q64_00650	COG0745	RESPONSE REGULATOR receiver
H1Q64_00660	COG5002	protein histidine kinase activity
H1Q64_00665	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
H1Q64_00675	COG4221	oxidoreductase activity
H1Q64_00700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1Q64_00720	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
H1Q64_00735	COG1045	serine acetyltransferase
H1Q64_00740	COG2945	thiolester hydrolase activity
H1Q64_00750	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
H1Q64_00765	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
H1Q64_00770	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H1Q64_00780	COG1192	Involved in chromosome partitioning
H1Q64_00785	COG0009	L-threonylcarbamoyladenylate synthase
H1Q64_00790	COG0277	FAD linked oxidase domain protein
H1Q64_00805	COG1960	acyl-CoA dehydrogenase activity
H1Q64_00825	COG0247	lactate metabolic process
H1Q64_00830	COG0277	FAD linked oxidase domain protein
H1Q64_00835	COG0277	FAD linked oxidase domain protein
H1Q64_00840	COG0257	Belongs to the bacterial ribosomal protein bL36 family
H1Q64_00850	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
H1Q64_00855	COG0842	Transport permease protein
H1Q64_00865	COG1131	(ABC) transporter
H1Q64_00875	COG1309	transcriptional regulator
H1Q64_00895	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H1Q64_00910	COG5554	nitrogen fixation
H1Q64_00935	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H1Q64_00950	COG0121	glutamine amidotransferase
H1Q64_01005	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
H1Q64_01010	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
H1Q64_01025	COG5420	small protein containing a coiled-coil domain
H1Q64_01080	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
H1Q64_01105	COG5002	protein histidine kinase activity
H1Q64_01105	COG2205	protein histidine kinase activity
H1Q64_01105	COG0784	Response regulator, receiver
H1Q64_01170	COG3437	response regulator, receiver
H1Q64_01170	COG0784	Response regulator, receiver
H1Q64_01180	COG1278	Cold shock
H1Q64_01185	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H1Q64_01190	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H1Q64_01210	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
H1Q64_01225	COG2154	pterin-4-alpha-carbinolamine dehydratase
H1Q64_01235	COG1104	cysteine desulfurase activity
H1Q64_01245	COG4948	Mandelate Racemase Muconate Lactonizing
H1Q64_01270	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
H1Q64_01275	COG2894	cell division
H1Q64_01280	COG0850	regulation of cytokinetic process
H1Q64_01285	COG1702	phosphate starvation-inducible protein PhoH
H1Q64_01300	COG1999	signal sequence binding
H1Q64_01310	COG0356	it plays a direct role in the translocation of protons across the membrane
H1Q64_01315	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
H1Q64_01320	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
H1Q64_01330	COG3384	dioxygenase
H1Q64_01340	COG0235	Class ii aldolase
H1Q64_01365	COG0437	4 iron, 4 sulfur cluster binding
H1Q64_01370	COG3383	formate dehydrogenase (NAD+) activity
H1Q64_01370	COG0243	molybdopterin cofactor binding
H1Q64_01395	COG0746	molybdenum cofactor guanylyltransferase activity
H1Q64_01400	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H1Q64_01415	COG1686	Belongs to the peptidase S11 family
H1Q64_01440	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
H1Q64_01455	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H1Q64_01465	COG0590	tRNA wobble adenosine to inosine editing
H1Q64_01490	COG2703	oxygen carrier activity
H1Q64_01495	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H1Q64_01520	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H1Q64_01530	COG2030	dehydratase
H1Q64_01535	COG0196	riboflavin kinase activity
H1Q64_01545	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
H1Q64_01550	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H1Q64_01555	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
H1Q64_01565	COG0612	Peptidase, M16
H1Q64_01570	COG0612	Peptidase, M16
H1Q64_01580	COG0166	Belongs to the GPI family
H1Q64_01650	COG0583	DNA-binding transcription factor activity
H1Q64_01660	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q64_01665	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H1Q64_01675	COG0596	Alpha beta hydrolase
H1Q64_01675	COG0508	dehydrogenase complex catalyzes the overall conversion of
H1Q64_01680	COG0022	dehydrogenase e1 component
H1Q64_01685	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H1Q64_01690	COG3199	ATP-NAD kinase
H1Q64_01695	COG3284	Transcriptional regulator
H1Q64_01705	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
H1Q64_01710	COG1082	Xylose isomerase domain protein TIM barrel
H1Q64_01730	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
H1Q64_01735	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q64_01745	COG0628	permease
H1Q64_01750	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1Q64_01755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1Q64_01765	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H1Q64_01850	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H1Q64_01865	COG0742	ribosomal rna small subunit methyltransferase
H1Q64_01870	COG1187	pseudouridine synthase activity
H1Q64_01875	COG3360	Dodecin
H1Q64_01880	COG0590	tRNA wobble adenosine to inosine editing
H1Q64_01885	COG4783	chaperone-mediated protein folding
H1Q64_01905	COG1570	exodeoxyribonuclease VII activity
H1Q64_01910	COG0418	dihydroorotase activity
H1Q64_01915	COG0124	histidyl-tRNA synthetase
H1Q64_01955	COG1058	Belongs to the CinA family
H1Q64_01955	COG1546	Belongs to the CinA family
H1Q64_01960	COG1489	DNA binding
H1Q64_01965	COG0024	Methionine aminopeptidase
H1Q64_01985	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H1Q64_02000	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
H1Q64_02005	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H1Q64_02015	COG2258	MOSC domain
H1Q64_02025	COG0583	DNA-binding transcription factor activity
H1Q64_02030	COG0047	phosphoribosylformylglycinamidine synthase activity
H1Q64_02035	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H1Q64_02045	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H1Q64_02055	COG2962	Rard protein
H1Q64_02065	COG1902	pentaerythritol trinitrate reductase activity
H1Q64_02080	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
H1Q64_02095	COG3279	Response regulator of the LytR AlgR family
H1Q64_02105	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H1Q64_02115	COG2205	protein histidine kinase activity
H1Q64_02160	COG0723	plastoquinol--plastocyanin reductase activity
H1Q64_02175	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H1Q64_02185	COG0463	Glycosyl transferase, family 2
H1Q64_02210	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H1Q64_02245	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
H1Q64_02270	COG2003	Belongs to the UPF0758 family
H1Q64_02275	COG2124	cytochrome p450
H1Q64_02305	COG0261	This protein binds to 23S rRNA in the presence of protein L20
H1Q64_02310	COG0211	Belongs to the bacterial ribosomal protein bL27 family
H1Q64_02315	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
H1Q64_02325	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H1Q64_02335	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H1Q64_02335	COG2010	Cytochrome c
H1Q64_02350	COG0799	negative regulation of ribosome biogenesis
H1Q64_02355	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
H1Q64_02360	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
H1Q64_02370	COG0793	Belongs to the peptidase S41A family
H1Q64_02380	COG1051	belongs to the nudix hydrolase family
H1Q64_02400	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
H1Q64_02410	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
H1Q64_02430	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H1Q64_02440	COG4974	Belongs to the 'phage' integrase family
H1Q64_02445	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1Q64_02455	COG0596	Alpha beta hydrolase
H1Q64_02470	COG4191	Histidine kinase
H1Q64_02480	COG4106	trans-aconitate 2-methyltransferase activity
H1Q64_02490	COG2202	Pas domain
H1Q64_02490	COG3920	Histidine kinase
H1Q64_02505	COG2226	methyltransferase
H1Q64_02510	COG0126	phosphoglycerate kinase activity
H1Q64_02520	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
H1Q64_02535	COG3474	cytochrome
H1Q64_02540	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
H1Q64_02570	COG4166	transmembrane transport
H1Q64_02575	COG4166	transmembrane transport
H1Q64_02580	COG4174	ABC transporter (Permease)
H1Q64_02610	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H1Q64_02615	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
H1Q64_02620	COG0625	glutathione transferase activity
H1Q64_02625	COG2358	TRAP transporter, solute receptor (TAXI family
H1Q64_02645	COG0587	DNA-directed DNA polymerase activity
H1Q64_02685	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H1Q64_02690	COG0625	glutathione transferase activity
H1Q64_02700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H1Q64_02705	COG0601	transmembrane transport
H1Q64_02715	COG1024	Enoyl-CoA hydratase
H1Q64_02730	COG0583	DNA-binding transcription factor activity
H1Q64_02755	COG5001	Diguanylate cyclase
H1Q64_02760	COG0625	glutathione transferase activity
H1Q64_02780	COG0156	8-amino-7-oxononanoate synthase activity
H1Q64_02795	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q64_02810	COG1322	Protein conserved in bacteria
H1Q64_02815	COG1278	Cold shock
H1Q64_02825	COG0242	peptide deformylase activity
H1Q64_02830	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
H1Q64_02835	COG0101	tRNA pseudouridine synthase activity
H1Q64_02855	COG2378	regulation of single-species biofilm formation
H1Q64_02860	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
H1Q64_02875	COG0335	large ribosomal subunit rRNA binding
H1Q64_02885	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H1Q64_02890	COG0228	four-way junction DNA binding
H1Q64_02895	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H1Q64_02935	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H1Q64_02950	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
H1Q64_02965	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H1Q64_02975	COG1131	(ABC) transporter
H1Q64_02985	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
H1Q64_03000	COG3206	protein involved in exopolysaccharide biosynthesis
H1Q64_03000	COG0489	protein tyrosine kinase activity
H1Q64_03010	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H1Q64_03020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H1Q64_03035	COG0438	transferase activity, transferring glycosyl groups
H1Q64_03070	COG1215	transferase activity, transferring glycosyl groups
H1Q64_03080	COG0230	Belongs to the bacterial ribosomal protein bL34 family
H1Q64_03090	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
H1Q64_03095	COG0706	membrane insertase activity
H1Q64_03100	COG0218	Necessary for normal cell division and for the maintenance of normal septation
H1Q64_03115	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
H1Q64_03125	COG0598	Magnesium transport protein CorA
H1Q64_03135	COG0825	malonyl-CoA metabolic process
H1Q64_03150	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H1Q64_03155	COG4974	Belongs to the 'phage' integrase family
H1Q64_03175	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
H1Q64_03180	COG0517	IMP dehydrogenase activity
H1Q64_03195	COG0271	Belongs to the BolA IbaG family
H1Q64_03225	COG1840	ABC-type Fe3 transport system, periplasmic component
H1Q64_03230	COG1741	Belongs to the pirin family
H1Q64_03235	COG1178	ABC-type Fe3 transport system permease component
H1Q64_03240	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
H1Q64_03250	COG0135	phosphoribosylanthranilate isomerase activity
H1Q64_03275	COG2423	ornithine cyclodeaminase activity
H1Q64_03285	COG0776	regulation of translation
H1Q64_03295	COG0539	negative regulation of cytoplasmic translation
H1Q64_03310	COG0405	Gamma-glutamyltransferase
H1Q64_03330	COG1741	Belongs to the pirin family
H1Q64_03350	COG2205	protein histidine kinase activity
H1Q64_03350	COG5002	protein histidine kinase activity
H1Q64_03350	COG0784	Response regulator, receiver
H1Q64_03360	COG0463	Glycosyl transferase, family 2
H1Q64_03370	COG0071	Belongs to the small heat shock protein (HSP20) family
H1Q64_03400	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H1Q64_03450	COG3162	membrane
H1Q64_03470	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H1Q64_03475	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H1Q64_03480	COG1987	bacterial-type flagellum assembly
H1Q64_03485	COG4106	trans-aconitate 2-methyltransferase activity
H1Q64_03510	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
H1Q64_03515	COG0513	Belongs to the DEAD box helicase family
H1Q64_03520	COG1970	mechanosensitive ion channel activity
H1Q64_03525	COG0653	protein targeting
H1Q64_03530	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H1Q64_03535	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
H1Q64_03545	COG0494	nUDIX hydrolase
H1Q64_03550	COG0514	ATP-dependent DNA helicase (RecQ)
H1Q64_03580	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
H1Q64_03585	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H1Q64_03620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1Q64_03630	COG0412	Dienelactone hydrolase
H1Q64_03635	COG0033	Phosphoglucomutase
H1Q64_03640	COG1278	Cold shock
H1Q64_03680	COG0444	Belongs to the ABC transporter superfamily
H1Q64_03685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H1Q64_03690	COG0601	transmembrane transport
H1Q64_03695	COG0747	negative chemotaxis
H1Q64_03755	COG0671	phosphoesterase, PA-phosphatase related
H1Q64_03765	COG3437	response regulator, receiver
H1Q64_03765	COG0784	Response regulator, receiver
H1Q64_03780	COG1983	PspC domain protein
H1Q64_03790	COG1842	Phage shock protein A
H1Q64_03800	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
H1Q64_03810	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
H1Q64_03825	COG3005	denitrification pathway
H1Q64_03830	COG1858	cytochrome C peroxidase
H1Q64_03835	COG0753	catalase activity
H1Q64_03840	COG0459	protein refolding
H1Q64_03845	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
H1Q64_03850	COG5425	PFAM Usg family protein
H1Q64_03855	COG3772	lysozyme
H1Q64_03860	COG0493	'glutamate synthase
H1Q64_03860	COG0543	2 iron, 2 sulfur cluster binding
H1Q64_03865	COG1612	heme a metabolic process
H1Q64_03895	COG4608	Belongs to the ABC transporter superfamily
H1Q64_03900	COG0668	transmembrane transport
H1Q64_03905	COG0784	Response regulator, receiver
H1Q64_03905	COG3437	response regulator, receiver
H1Q64_03910	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
H1Q64_03925	COG3800	Transcriptional regulator
H1Q64_03925	COG1396	sequence-specific DNA binding
H1Q64_03930	COG2224	Isocitrate lyase
H1Q64_03935	COG0693	protein deglycase activity
H1Q64_03950	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
H1Q64_03955	COG0674	pyruvate-flavodoxin oxidoreductase activity
H1Q64_03955	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
H1Q64_03960	COG1013	pyruvate-flavodoxin oxidoreductase activity
H1Q64_03980	COG3685	Protein conserved in bacteria
H1Q64_04000	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
H1Q64_04005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H1Q64_04015	COG0747	negative chemotaxis
H1Q64_04025	COG0606	chelatase, subunit chli
H1Q64_04045	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H1Q64_04050	COG0347	Belongs to the P(II) protein family
H1Q64_04055	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1Q64_04060	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
H1Q64_04065	COG0667	Aldo Keto reductase
H1Q64_04080	COG4181	ATPase activity
H1Q64_04090	COG3706	GGDEF domain
H1Q64_04095	COG0484	heat shock protein binding
H1Q64_04100	COG0443	Heat shock 70 kDa protein
H1Q64_04130	COG1420	regulation of RNA biosynthetic process
H1Q64_04135	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
H1Q64_04140	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
H1Q64_04145	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H1Q64_04180	COG0792	nuclease activity
H1Q64_04185	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
H1Q64_04205	COG1366	Belongs to the anti-sigma-factor antagonist family
H1Q64_04215	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
H1Q64_04255	COG2205	protein histidine kinase activity
H1Q64_04255	COG0784	Response regulator, receiver
H1Q64_04265	COG0180	Tryptophanyl-tRNA synthetase
H1Q64_04270	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
H1Q64_04280	COG3012	SEC-C Motif Domain Protein
H1Q64_04295	COG0110	maltose O-acetyltransferase activity
H1Q64_04300	COG1309	transcriptional regulator
H1Q64_04305	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q64_04315	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
H1Q64_04320	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
H1Q64_04325	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
H1Q64_04350	COG0438	transferase activity, transferring glycosyl groups
H1Q64_04355	COG3706	GGDEF domain
H1Q64_04360	COG0438	transferase activity, transferring glycosyl groups
H1Q64_04370	COG1132	(ABC) transporter
H1Q64_04375	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1Q64_04375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H1Q64_04405	COG0601	transmembrane transport
H1Q64_04410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H1Q64_04420	COG1234	tRNA 3'-trailer cleavage
H1Q64_04440	COG0745	RESPONSE REGULATOR receiver
H1Q64_04515	COG0357	Ribosomal RNA small subunit methyltransferase G
H1Q64_04520	COG0445	tRNA wobble uridine modification
H1Q64_04530	COG3411	Ferredoxin
H1Q64_04540	COG1331	Highly conserved protein containing a thioredoxin domain
H1Q64_04545	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H1Q64_04555	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H1Q64_04560	COG0237	dephospho-CoA kinase activity
H1Q64_04585	COG1981	membrane
H1Q64_04595	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
H1Q64_04600	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
H1Q64_04605	COG3030	protein affecting phage T7 exclusion by the F plasmid
H1Q64_04610	COG4395	Tim44
H1Q64_04615	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
H1Q64_04670	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
H1Q64_04675	COG0488	(ABC) transporter
H1Q64_04680	COG2205	protein histidine kinase activity
H1Q64_04695	COG1556	Lactate utilization protein
H1Q64_04700	COG1139	Iron-sulfur cluster binding protein
H1Q64_04705	COG0247	lactate metabolic process
H1Q64_04730	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H1Q64_04745	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
H1Q64_04750	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H1Q64_04760	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H1Q64_04775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H1Q64_04780	COG0730	response to heat
H1Q64_04805	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
H1Q64_04815	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
H1Q64_04820	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
H1Q64_04850	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H1Q64_04855	COG1702	phosphate starvation-inducible protein PhoH
H1Q64_04865	COG1253	flavin adenine dinucleotide binding
H1Q64_04870	COG0815	Transfers the fatty acyl group on membrane lipoproteins
H1Q64_04875	COG1396	sequence-specific DNA binding
H1Q64_04880	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
H1Q64_04885	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H1Q64_04890	COG2329	Antibiotic biosynthesis monooxygenase
H1Q64_04895	COG0779	Required for maturation of 30S ribosomal subunits
H1Q64_04915	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
H1Q64_04920	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H1Q64_04930	COG1185	polyribonucleotide nucleotidyltransferase activity
H1Q64_04945	COG2321	neutral zinc metallopeptidase
H1Q64_04955	COG1509	lysine 2,3-aminomutase activity
H1Q64_04960	COG0584	glycerophosphoryl diester phosphodiesterase
H1Q64_04975	COG1592	Rubrerythrin
H1Q64_05005	COG0039	L-malate dehydrogenase activity
H1Q64_05015	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
H1Q64_05020	COG4166	transmembrane transport
H1Q64_05030	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H1Q64_05035	COG2226	methyltransferase
H1Q64_05040	COG0859	PFAM glycosyl transferase family 9
H1Q64_05040	COG0457	Tetratricopeptide repeat
H1Q64_05050	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
H1Q64_05060	COG1024	Enoyl-CoA hydratase
H1Q64_05065	COG0268	Binds directly to 16S ribosomal RNA
H1Q64_05070	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
H1Q64_05075	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
H1Q64_05080	COG3842	ATPase activity
H1Q64_05100	COG1176	ABC-type spermidine putrescine transport system, permease component I
H1Q64_05105	COG1177	transmembrane transport
H1Q64_05120	COG2132	Multicopper oxidase
H1Q64_05170	COG2217	Heavy metal translocating P-type atpase
H1Q64_05175	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1Q64_05180	COG0280	phosphate acetyltransferase
H1Q64_05180	COG0281	malic enzyme
H1Q64_05200	COG3547	Transposase (IS116 IS110 IS902 family)
H1Q64_05210	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H1Q64_05215	COG0573	inorganic phosphate transmembrane transporter activity
H1Q64_05225	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H1Q64_05235	COG0745	RESPONSE REGULATOR receiver
H1Q64_05250	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H1Q64_05260	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H1Q64_05270	COG0756	dUTP diphosphatase activity
H1Q64_05275	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H1Q64_05280	COG2204	response regulator
H1Q64_05285	COG1278	Cold shock
H1Q64_05290	COG0784	Response regulator, receiver
H1Q64_05290	COG2205	protein histidine kinase activity
H1Q64_05290	COG5002	protein histidine kinase activity
H1Q64_05295	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H1Q64_05300	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H1Q64_05300	COG1321	iron dependent repressor
H1Q64_05305	COG1121	(ABC) transporter
H1Q64_05310	COG0803	Belongs to the bacterial solute-binding protein 9 family
H1Q64_05345	COG2205	protein histidine kinase activity
H1Q64_05345	COG2202	Pas domain
H1Q64_05365	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H1Q64_05370	COG1253	flavin adenine dinucleotide binding
H1Q64_05390	COG0583	DNA-binding transcription factor activity
H1Q64_05395	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
H1Q64_05415	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
H1Q64_05435	COG0291	Belongs to the bacterial ribosomal protein bL35 family
H1Q64_05440	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
H1Q64_05445	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
H1Q64_05460	COG3437	response regulator, receiver
H1Q64_05460	COG0784	Response regulator, receiver
H1Q64_05470	COG0583	DNA-binding transcription factor activity
H1Q64_05485	COG0481	GTPase activity
H1Q64_05490	COG0297	glycogen (starch) synthase activity
H1Q64_05495	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
H1Q64_05500	COG0004	ammonium transporteR
H1Q64_05520	COG3806	Anti-sigma factor
H1Q64_05525	COG1595	DNA-templated transcription, initiation
H1Q64_05535	COG0820	rRNA (adenine-C2-)-methyltransferase activity
H1Q64_05550	COG0137	argininosuccinate synthase activity
H1Q64_05565	COG2897	thiosulfate sulfurtransferase activity
H1Q64_05570	COG3339	Conserved Protein
H1Q64_05575	COG0697	spore germination
H1Q64_05580	COG4235	cytochrome complex assembly
H1Q64_05585	COG3088	subunit of a heme lyase
H1Q64_05590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H1Q64_05595	COG1138	Cytochrome C-type biogenesis protein
H1Q64_05600	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
H1Q64_05610	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H1Q64_05630	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H1Q64_05635	COG4133	protoheme IX ABC transporter activity
H1Q64_05640	COG2985	domain, Protein
H1Q64_05645	COG2985	domain, Protein
H1Q64_05685	COG1872	DUF167
H1Q64_05690	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
H1Q64_05695	COG0598	Magnesium transport protein CorA
H1Q64_05705	COG2154	pterin-4-alpha-carbinolamine dehydratase
H1Q64_05715	COG1573	uracil-dna glycosylase
H1Q64_05720	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H1Q64_05725	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H1Q64_05735	COG0583	DNA-binding transcription factor activity
H1Q64_05745	COG1074	ATP-dependent DNA helicase activity
H1Q64_05750	COG2887	Belongs to the helicase family. UvrD subfamily
H1Q64_05755	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H1Q64_05795	COG1252	NADH dehydrogenase
H1Q64_05800	COG2205	protein histidine kinase activity
H1Q64_05805	COG0784	Response regulator, receiver
H1Q64_05805	COG2205	protein histidine kinase activity
H1Q64_05805	COG5002	protein histidine kinase activity
H1Q64_05810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1Q64_05815	COG0133	tryptophan synthase activity
H1Q64_05825	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
H1Q64_05830	COG0285	dihydrofolate synthase activity
H1Q64_05855	COG2205	protein histidine kinase activity
H1Q64_05855	COG2202	Pas domain
H1Q64_05860	COG0302	gtp cyclohydrolase
H1Q64_05870	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H1Q64_05880	COG0302	gtp cyclohydrolase
H1Q64_05885	COG2967	ApaG domain
H1Q64_05915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1Q64_05930	COG5002	protein histidine kinase activity
H1Q64_05950	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
H1Q64_05955	COG4191	Histidine kinase
H1Q64_05955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1Q64_05965	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H1Q64_05975	COG2885	chlorophyll binding
H1Q64_06005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H1Q64_06020	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
H1Q64_06035	COG2264	protein methyltransferase activity
H1Q64_06040	COG0181	hydroxymethylbilane synthase activity
H1Q64_06060	COG2350	Protein conserved in bacteria
H1Q64_06075	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H1Q64_06090	COG5508	conserved small protein
H1Q64_06095	COG0501	Belongs to the peptidase M48B family
H1Q64_06120	COG0138	bifunctional purine biosynthesis protein purh
H1Q64_06145	COG2264	protein methyltransferase activity
H1Q64_06150	COG2902	Dehydrogenase
H1Q64_06155	COG2770	Histidine kinase
H1Q64_06155	COG3437	response regulator, receiver
H1Q64_06175	COG0679	Auxin Efflux Carrier
H1Q64_06180	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H1Q64_06195	COG3118	belongs to the thioredoxin family
H1Q64_06200	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
H1Q64_06205	COG2835	tetraacyldisaccharide 4'-kinase activity
H1Q64_06240	COG1285	pathogenesis
H1Q64_06245	COG2814	Major facilitator Superfamily
H1Q64_06255	COG0784	Response regulator, receiver
H1Q64_06255	COG2205	protein histidine kinase activity
H1Q64_06275	COG0395	ABC-type sugar transport system, permease component
H1Q64_06300	COG0513	Belongs to the DEAD box helicase family
H1Q64_06330	COG1366	Belongs to the anti-sigma-factor antagonist family
H1Q64_06340	COG0745	RESPONSE REGULATOR receiver
H1Q64_06375	COG1366	Belongs to the anti-sigma-factor antagonist family
H1Q64_06385	COG2201	protein-glutamate methylesterase activity
H1Q64_06390	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
H1Q64_06400	COG0840	transmembrane signaling receptor activity
H1Q64_06405	COG0835	chemotaxis
H1Q64_06410	COG0643	Histidine kinase
H1Q64_06410	COG2198	Histidine kinase
H1Q64_06415	COG0745	RESPONSE REGULATOR receiver
H1Q64_06425	COG5002	protein histidine kinase activity
H1Q64_06435	COG5002	protein histidine kinase activity
H1Q64_06435	COG2176	DNA-directed DNA polymerase activity
H1Q64_06440	COG0745	RESPONSE REGULATOR receiver
H1Q64_06455	COG2917	probably involved in intracellular septation
H1Q64_06465	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H1Q64_06470	COG0552	protein localization to endoplasmic reticulum
H1Q64_06475	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H1Q64_06480	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
H1Q64_06525	COG2301	Belongs to the HpcH HpaI aldolase family
H1Q64_06530	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
H1Q64_06545	COG0582	viral genome integration into host DNA
H1Q64_06610	COG0305	Participates in initiation and elongation during chromosome replication
H1Q64_06680	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H1Q64_06685	COG3706	GGDEF domain
H1Q64_06690	COG2205	protein histidine kinase activity
H1Q64_06695	COG0508	dehydrogenase complex catalyzes the overall conversion of
H1Q64_06710	COG0045	succinate-CoA ligase (ADP-forming) activity
H1Q64_06715	COG0039	L-malate dehydrogenase activity
H1Q64_06730	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
H1Q64_06735	COG2076	Multidrug Resistance protein
H1Q64_06750	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H1Q64_06750	COG1199	ATP-dependent helicase activity
H1Q64_06765	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
H1Q64_06775	COG0840	transmembrane signaling receptor activity
H1Q64_06775	COG2972	Histidine kinase
H1Q64_06785	COG2084	Dehydrogenase
H1Q64_06795	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H1Q64_06830	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H1Q64_06945	COG0167	dihydroorotate dehydrogenase activity
H1Q64_06955	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
H1Q64_06960	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
H1Q64_06965	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
H1Q64_07015	COG0058	SHG alpha-glucan phosphorylase activity
H1Q64_07020	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
H1Q64_07050	COG1757	Na H antiporter
H1Q64_07105	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
H1Q64_07110	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H1Q64_07120	COG0783	Belongs to the Dps family
H1Q64_07130	COG0492	ferredoxin-NADP+ reductase activity
H1Q64_07145	COG3660	Nucleoside-diphosphate-sugar epimerase
H1Q64_07150	COG1522	sequence-specific DNA binding
H1Q64_07160	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H1Q64_07165	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
H1Q64_07190	COG1674	ftsk spoiiie
H1Q64_07200	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H1Q64_07210	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H1Q64_07215	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q64_07220	COG1238	metal cluster binding
H1Q64_07240	COG1012	belongs to the aldehyde dehydrogenase family
H1Q64_07255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1Q64_07255	COG2205	protein histidine kinase activity
H1Q64_07265	COG1131	(ABC) transporter
H1Q64_07315	COG1116	anion transmembrane transporter activity
H1Q64_07355	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
H1Q64_07375	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H1Q64_07380	COG2205	protein histidine kinase activity
H1Q64_07380	COG0784	Response regulator, receiver
H1Q64_07390	COG0745	RESPONSE REGULATOR receiver
H1Q64_07395	COG2766	serine protein kinase
H1Q64_07400	COG2718	Belongs to the UPF0229 family
H1Q64_07405	COG2719	SpoVR family
H1Q64_07420	COG1643	Atp-dependent helicase
H1Q64_07425	COG1116	anion transmembrane transporter activity
H1Q64_07445	COG0745	RESPONSE REGULATOR receiver
H1Q64_07470	COG0330	HflC and HflK could
H1Q64_07475	COG0628	permease
H1Q64_07485	COG3180	Ammonia monooxygenase
H1Q64_07490	COG2988	succinylglutamate desuccinylase activity
H1Q64_07530	COG2205	protein histidine kinase activity
H1Q64_07530	COG2202	Pas domain
H1Q64_07540	COG2205	protein histidine kinase activity
H1Q64_07550	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H1Q64_07560	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
H1Q64_07590	COG2197	response regulator
H1Q64_07595	COG2197	response regulator
H1Q64_07600	COG0210	DNA helicase
H1Q64_07615	COG2264	protein methyltransferase activity
H1Q64_07625	COG0006	proline dipeptidase activity
H1Q64_07625	COG0006	proline dipeptidase activity
H1Q64_07630	COG0745	RESPONSE REGULATOR receiver
H1Q64_07645	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H1Q64_07650	COG0497	DNA recombination
H1Q64_07670	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
H1Q64_07685	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H1Q64_07690	COG0849	cell division
H1Q64_07695	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H1Q64_07700	COG1181	Belongs to the D-alanine--D-alanine ligase family
H1Q64_07705	COG0812	UDP-N-acetylmuramate dehydrogenase activity
H1Q64_07710	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H1Q64_07720	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
H1Q64_07735	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H1Q64_07745	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H1Q64_07765	COG2001	Belongs to the MraZ family
H1Q64_07785	COG0488	(ABC) transporter
H1Q64_07790	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
H1Q64_07805	COG0277	FAD linked oxidase domain protein
H1Q64_07810	COG2084	Dehydrogenase
H1Q64_07850	COG0142	geranyltranstransferase activity
H1Q64_07860	COG2890	protein-(glutamine-N5) methyltransferase activity
H1Q64_07880	COG0752	glycyl-tRNA synthetase alpha subunit
H1Q64_07885	COG0751	glycine-tRNA ligase activity
H1Q64_07890	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H1Q64_07895	COG1346	cytolysis
H1Q64_07900	COG1380	Effector of murein hydrolase LrgA
H1Q64_07905	COG1073	alpha beta
H1Q64_07935	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
H1Q64_07970	COG1278	Cold shock
H1Q64_07975	COG3409	Peptidoglycan-binding domain 1 protein
H1Q64_07975	COG0860	N-Acetylmuramoyl-L-alanine amidase
H1Q64_07980	COG3108	Peptidase M15
H1Q64_07995	COG0840	transmembrane signaling receptor activity
H1Q64_08025	COG0511	ligase activity, forming carbon-carbon bonds
H1Q64_08030	COG0439	Biotin carboxylase
H1Q64_08035	COG3719	Belongs to the RNase T2 family
H1Q64_08065	COG1280	lysine exporter protein (LysE YggA)
H1Q64_08075	COG1663	tetraacyldisaccharide 4'-kinase activity
H1Q64_08080	COG1519	Transferase
H1Q64_08090	COG0438	transferase activity, transferring glycosyl groups
H1Q64_08100	COG1597	lipid kinase activity
H1Q64_08115	COG0312	modulator of DNA gyrase
H1Q64_08130	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
H1Q64_08140	COG2264	protein methyltransferase activity
H1Q64_08155	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H1Q64_08165	COG0436	Aminotransferase
H1Q64_08195	COG1530	ribonuclease E activity
H1Q64_08200	COG0860	N-Acetylmuramoyl-L-alanine amidase
H1Q64_08205	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
H1Q64_08245	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H1Q64_08265	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H1Q64_08275	COG1309	transcriptional regulator
H1Q64_08280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1Q64_08290	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
H1Q64_08300	COG0673	inositol 2-dehydrogenase activity
H1Q64_08330	COG0411	ABC transporter
H1Q64_08340	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H1Q64_08345	COG2972	Histidine kinase
H1Q64_08345	COG0840	transmembrane signaling receptor activity
H1Q64_08355	COG1940	carbohydrate kinase activity
H1Q64_08365	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
H1Q64_08465	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
H1Q64_08470	COG0081	regulation of translation
H1Q64_08475	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
H1Q64_08480	COG0222	ribosome binding
H1Q64_08485	COG0085	RNA polymerase activity
H1Q64_08490	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
H1Q64_08505	COG0049	tRNA binding
H1Q64_08520	COG0051	transcription antitermination factor activity, RNA binding
H1Q64_08530	COG0088	Forms part of the polypeptide exit tunnel
H1Q64_08535	COG0089	rRNA binding
H1Q64_08540	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
H1Q64_08545	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
H1Q64_08550	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
H1Q64_08555	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
H1Q64_08560	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
H1Q64_08565	COG0255	Belongs to the universal ribosomal protein uL29 family
H1Q64_08570	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
H1Q64_08580	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
H1Q64_08590	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
H1Q64_08595	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
H1Q64_08600	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
H1Q64_08615	COG1841	ribosomal large subunit assembly
H1Q64_08620	COG0200	Binds to the 23S rRNA
H1Q64_08625	COG0201	protein transport
H1Q64_08630	COG0563	adenylate kinase activity
H1Q64_08635	COG2186	Transcriptional regulator
H1Q64_08650	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
H1Q64_08670	COG0071	Belongs to the small heat shock protein (HSP20) family
H1Q64_08680	COG0254	rRNA binding
H1Q64_08685	COG1132	(ABC) transporter
H1Q64_08695	COG0500	methyltransferase
H1Q64_08715	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
H1Q64_08760	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
H1Q64_08770	COG4786	Flagellar basal body rod
H1Q64_08775	COG4786	Flagellar basal body rod
H1Q64_08815	COG1360	Flagellar Motor Protein
H1Q64_08835	COG1338	Plays a role in the flagellum-specific transport system
H1Q64_08850	COG2257	FlhB HrpN YscU SpaS Family
H1Q64_08855	COG1815	bacterial-type flagellum-dependent cell motility
H1Q64_08860	COG1558	bacterial-type flagellum-dependent cell motility
H1Q64_08865	COG1677	Flagellar hook-basal body complex protein FliE
H1Q64_08870	COG1987	bacterial-type flagellum assembly
H1Q64_08875	COG1684	flagellar biosynthetic protein fliR
H1Q64_08880	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H1Q64_08900	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
H1Q64_08915	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H1Q64_08925	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H1Q64_08955	COG0473	3-isopropylmalate dehydrogenase activity
H1Q64_08975	COG3932	Exopolysaccharide synthesis, ExoD
H1Q64_08985	COG0538	isocitrate dehydrogenase activity
H1Q64_09025	COG0456	acetyltransferase
H1Q64_09025	COG1214	PFAM Peptidase M22, glycoprotease
H1Q64_09030	COG2890	protein-(glutamine-N5) methyltransferase activity
H1Q64_09035	COG1393	Belongs to the ArsC family
H1Q64_09040	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H1Q64_09050	COG1403	HNH endonuclease
H1Q64_09060	COG0505	Belongs to the CarA family
H1Q64_09080	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H1Q64_09105	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
H1Q64_09115	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H1Q64_09145	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H1Q64_09145	COG0551	DNA topoisomerase type I activity
H1Q64_09155	COG0251	oxidation-reduction process
H1Q64_09160	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
H1Q64_09170	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H1Q64_09185	COG0628	permease
H1Q64_09195	COG1116	anion transmembrane transporter activity
H1Q64_09200	COG0390	transport system, permease component
H1Q64_09210	COG0784	Response regulator, receiver
H1Q64_09210	COG5002	protein histidine kinase activity
H1Q64_09210	COG2198	Histidine kinase
H1Q64_09225	COG0616	signal peptide processing
H1Q64_09235	COG0745	RESPONSE REGULATOR receiver
H1Q64_09245	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
H1Q64_09255	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
H1Q64_09260	COG1295	ribonuclease BN
H1Q64_09265	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H1Q64_09280	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H1Q64_09290	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
H1Q64_09295	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H1Q64_09300	COG0515	serine threonine protein kinase
H1Q64_09300	COG3266	domain, Protein
H1Q64_09315	COG0564	pseudouridine synthase activity
H1Q64_09345	COG0741	lytic transglycosylase activity
H1Q64_09355	COG5487	UPF0391 membrane protein
H1Q64_09365	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H1Q64_09375	COG0312	modulator of DNA gyrase
H1Q64_09385	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H1Q64_09390	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H1Q64_09395	COG0109	protoheme IX farnesyltransferase activity
H1Q64_09415	COG3346	SURF1 family
H1Q64_09420	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
H1Q64_09425	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
H1Q64_09435	COG0612	Peptidase, M16
H1Q64_09440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H1Q64_09450	COG1678	Uncharacterized ACR, COG1678
H1Q64_09455	COG4232	protein-disulfide reductase activity
H1Q64_09460	COG0678	peroxiredoxin activity
H1Q64_09465	COG0318	PFAM AMP-dependent synthetase and ligase
H1Q64_09470	COG0328	RNA-DNA hybrid ribonuclease activity
H1Q64_09475	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H1Q64_09485	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
H1Q64_09500	COG0404	The glycine cleavage system catalyzes the degradation of glycine
H1Q64_09505	COG0509	glycine decarboxylation via glycine cleavage system
H1Q64_09510	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
H1Q64_09515	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
H1Q64_09535	COG0483	inositol monophosphate 1-phosphatase activity
H1Q64_09540	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
H1Q64_09550	COG0604	alcohol dehydrogenase
H1Q64_09555	COG2067	long-chain fatty acid transport protein
H1Q64_09560	COG0730	response to heat
H1Q64_09565	COG0352	thiamine-phosphate diphosphorylase activity
H1Q64_09570	COG1830	Aldolase
H1Q64_09615	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H1Q64_09620	COG1692	metallophosphoesterase
H1Q64_09625	COG0217	transcriptional regulatory protein
H1Q64_09640	COG2255	four-way junction helicase activity
H1Q64_09645	COG0824	Thioesterase
H1Q64_09655	COG0848	biopolymer transport protein
H1Q64_09670	COG2885	chlorophyll binding
H1Q64_09690	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H1Q64_09695	COG0438	transferase activity, transferring glycosyl groups
H1Q64_09710	COG0367	asparagine synthase
H1Q64_09720	COG0697	spore germination
H1Q64_09730	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H1Q64_09740	COG1765	OsmC-like protein
H1Q64_09745	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q64_09750	COG2076	Multidrug Resistance protein
H1Q64_09775	COG3437	response regulator, receiver
H1Q64_09775	COG0784	Response regulator, receiver
H1Q64_09790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1Q64_09790	COG4191	Histidine kinase
H1Q64_09820	COG4520	surface antigen
H1Q64_09825	COG0259	pyridoxamine-phosphate oxidase activity
H1Q64_09840	COG0840	transmembrane signaling receptor activity
H1Q64_09850	COG1234	tRNA 3'-trailer cleavage
H1Q64_09855	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H1Q64_09870	COG0523	cobalamin synthesis protein
H1Q64_09875	COG0735	belongs to the Fur family
H1Q64_09885	COG0415	Belongs to the DNA photolyase family
H1Q64_09890	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
H1Q64_09900	COG1201	RNA secondary structure unwinding
H1Q64_09910	COG2226	methyltransferase
H1Q64_09925	COG0508	dehydrogenase complex catalyzes the overall conversion of
H1Q64_09925	COG0596	Alpha beta hydrolase
H1Q64_09930	COG1846	Transcriptional regulator
H1Q64_09940	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1Q64_09985	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H1Q64_09990	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1Q64_09995	COG0318	PFAM AMP-dependent synthetase and ligase
H1Q64_10000	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q64_10005	COG1960	acyl-CoA dehydrogenase activity
H1Q64_10020	COG2833	Protein of unknown function (DUF455)
H1Q64_10025	COG1218	3'(2'),5'-bisphosphate nucleotidase
H1Q64_10040	COG0366	Alpha amylase catalytic
H1Q64_10045	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
H1Q64_10055	COG0745	RESPONSE REGULATOR receiver
H1Q64_10060	COG1640	4-alpha-glucanotransferase
H1Q64_10090	COG1671	Belongs to the UPF0178 family
H1Q64_10095	COG0488	(ABC) transporter
H1Q64_10110	COG2853	Lipoprotein
H1Q64_10115	COG2226	methyltransferase
H1Q64_10130	COG0646	methionine synthase
H1Q64_10130	COG1410	methionine synthase
H1Q64_10145	COG3706	GGDEF domain
H1Q64_10150	COG2070	2-Nitropropane dioxygenase
H1Q64_10155	COG0243	molybdopterin cofactor binding
H1Q64_10170	COG2824	Alkylphosphonate utilization operon protein PhnA
H1Q64_10200	COG2205	protein histidine kinase activity
H1Q64_10220	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
H1Q64_10225	COG1752	Esterase of the alpha-beta hydrolase superfamily
H1Q64_10240	COG1773	rubredoxin
H1Q64_10250	COG3108	Peptidase M15
H1Q64_10305	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H1Q64_10315	COG0546	phosphoglycolate phosphatase activity
H1Q64_10360	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
H1Q64_10365	COG2807	transmembrane transport
H1Q64_10370	COG3546	catalase activity
H1Q64_10390	COG3411	Ferredoxin
H1Q64_10395	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H1Q64_10405	COG1024	Enoyl-CoA hydratase
H1Q64_10415	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H1Q64_10475	COG1492	cobalamin metabolic process
H1Q64_10480	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H1Q64_10500	COG3424	synthase
H1Q64_10505	COG1755	Isoprenylcysteine carboxyl methyltransferase
H1Q64_10515	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1Q64_10525	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1Q64_10560	COG1217	gtp-binding protein TYPA
H1Q64_10580	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
H1Q64_10590	COG2313	pseudouridylate synthase activity
H1Q64_10600	COG1793	dna ligase
H1Q64_10610	COG2153	protein acetylation
H1Q64_10630	COG3685	Protein conserved in bacteria
H1Q64_10650	COG0698	ribose 5-phosphate isomerase
H1Q64_10655	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
H1Q64_10660	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
H1Q64_10665	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H1Q64_10665	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H1Q64_10675	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H1Q64_10675	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H1Q64_10680	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
H1Q64_10685	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H1Q64_10690	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H1Q64_10700	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
H1Q64_10720	COG0333	Belongs to the bacterial ribosomal protein bL32 family
H1Q64_10725	COG0416	fatty acid biosynthetic process
H1Q64_10730	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H1Q64_10750	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H1Q64_10750	COG4651	solute:proton antiporter activity
H1Q64_10765	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1Q64_10780	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H1Q64_10780	COG1648	precorrin-2 dehydrogenase activity
H1Q64_10785	COG0175	sulfate reduction
H1Q64_10790	COG0175	sulfate reduction
H1Q64_10800	COG1116	anion transmembrane transporter activity
H1Q64_10800	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1Q64_10810	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
H1Q64_10830	COG0318	PFAM AMP-dependent synthetase and ligase
H1Q64_10835	COG0789	Transcriptional regulator
H1Q64_10850	COG2814	Major facilitator Superfamily
H1Q64_10855	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
H1Q64_10890	COG0840	transmembrane signaling receptor activity
H1Q64_10930	COG2197	response regulator
H1Q64_10940	COG2197	response regulator
H1Q64_10960	COG1160	GTP binding
H1Q64_10965	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H1Q64_10965	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H1Q64_11010	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q64_11020	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H1Q64_11025	COG1763	Mo-molybdopterin cofactor biosynthetic process
H1Q64_11035	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
H1Q64_11040	COG0314	molybdopterin synthase activity
H1Q64_11050	COG1280	lysine exporter protein (LysE YggA)
H1Q64_11090	COG4957	zinc ion binding
H1Q64_11130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H1Q64_11135	COG0174	glutamine synthetase
H1Q64_11145	COG3842	ATPase activity
H1Q64_11150	COG1176	ABC-type spermidine putrescine transport system, permease component I
H1Q64_11155	COG1177	transmembrane transport
H1Q64_11160	COG2957	Belongs to the agmatine deiminase family
H1Q64_11170	COG0631	protein serine/threonine phosphatase activity
H1Q64_11185	COG0321	lipoyl(octanoyl) transferase activity
H1Q64_11185	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
H1Q64_11190	COG0084	hydrolase, TatD family'
H1Q64_11195	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H1Q64_11200	COG0470	DNA polymerase III
H1Q64_11205	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
H1Q64_11210	COG1686	Belongs to the peptidase S11 family
H1Q64_11225	COG0840	transmembrane signaling receptor activity
H1Q64_11230	COG0525	valine-tRNA ligase activity
H1Q64_11240	COG1538	Outer membrane efflux protein
H1Q64_11250	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
H1Q64_11280	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H1Q64_11285	COG0494	nUDIX hydrolase
H1Q64_11295	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
H1Q64_11300	COG2897	thiosulfate sulfurtransferase activity
H1Q64_11320	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H1Q64_11325	COG1126	abc transporter atp-binding protein
H1Q64_11330	COG0765	amino acid transport
H1Q64_11335	COG4597	amino acid ABC transporter
H1Q64_11340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1Q64_11345	COG0626	cystathionine gamma-synthase activity
H1Q64_11395	COG0123	including yeast histone deacetylase and acetoin utilization protein
H1Q64_11425	COG2358	TRAP transporter, solute receptor (TAXI family
H1Q64_11460	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
H1Q64_11460	COG3608	succinylglutamate desuccinylase aspartoacylase
H1Q64_11465	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
H1Q64_11470	COG0512	Glutamine amidotransferase of anthranilate synthase
H1Q64_11475	COG0737	Belongs to the 5'-nucleotidase family
H1Q64_11485	COG0686	Belongs to the AlaDH PNT family
H1Q64_11500	COG0559	Belongs to the binding-protein-dependent transport system permease family
H1Q64_11520	COG1846	Transcriptional regulator
H1Q64_11525	COG1024	Enoyl-CoA hydratase
H1Q64_11530	COG1597	lipid kinase activity
H1Q64_11540	COG0113	porphobilinogen synthase activity
H1Q64_11545	COG1881	PFAM PEBP family protein
H1Q64_11555	COG2813	Specifically methylates the guanine in position
H1Q64_11560	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
H1Q64_11565	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H1Q64_11580	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H1Q64_11585	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H1Q64_11600	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H1Q64_11605	COG0360	Binds together with S18 to 16S ribosomal RNA
H1Q64_11610	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
H1Q64_11620	COG0359	binds to the 23S rRNA
H1Q64_11625	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H1Q64_11630	COG0305	Participates in initiation and elongation during chromosome replication
H1Q64_11635	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H1Q64_11640	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H1Q64_11645	COG1127	ABC transporter
H1Q64_11660	COG0024	Methionine aminopeptidase
H1Q64_11675	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
H1Q64_11685	COG0564	pseudouridine synthase activity
H1Q64_11700	COG0784	Response regulator, receiver
H1Q64_11700	COG2198	Histidine kinase
H1Q64_11700	COG2205	protein histidine kinase activity
H1Q64_11705	COG2197	response regulator
H1Q64_11710	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H1Q64_11710	COG2885	chlorophyll binding
H1Q64_11760	COG1940	carbohydrate kinase activity
H1Q64_11780	COG0463	Glycosyl transferase, family 2
H1Q64_11800	COG0704	Plays a role in the regulation of phosphate uptake
H1Q64_11810	COG1846	Transcriptional regulator
H1Q64_11835	COG1396	sequence-specific DNA binding
H1Q64_11865	COG0640	Transcriptional regulator
H1Q64_11880	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
H1Q64_11890	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
H1Q64_11895	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
H1Q64_11900	COG0830	nickel cation binding
H1Q64_11905	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
H1Q64_11910	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H1Q64_11915	COG0804	urea catabolic process
H1Q64_11920	COG0832	Belongs to the urease beta subunit family
H1Q64_11925	COG0831	urea catabolic process
H1Q64_11930	COG1819	glycosyl
H1Q64_11935	COG0829	nickel cation binding
H1Q64_11950	COG2197	response regulator
H1Q64_11955	COG2197	response regulator
H1Q64_11960	COG0693	protein deglycase activity
H1Q64_11975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H1Q64_12005	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H1Q64_12005	COG0574	Belongs to the PEP-utilizing enzyme family
H1Q64_12015	COG0469	pyruvate kinase activity
H1Q64_12020	COG1802	Transcriptional regulator
H1Q64_12025	COG0352	thiamine-phosphate diphosphorylase activity
H1Q64_12025	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
H1Q64_12030	COG3960	tartronate-semialdehyde synthase activity
H1Q64_12035	COG3622	Belongs to the hyi family
H1Q64_12040	COG2084	Dehydrogenase
H1Q64_12055	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
H1Q64_12070	COG2814	Major facilitator Superfamily
H1Q64_12075	COG0583	DNA-binding transcription factor activity
H1Q64_12085	COG0045	succinate-CoA ligase (ADP-forming) activity
H1Q64_12090	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H1Q64_12125	COG0517	IMP dehydrogenase activity
H1Q64_12130	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H1Q64_12140	COG0123	including yeast histone deacetylase and acetoin utilization protein
H1Q64_12155	COG0656	L-ascorbic acid biosynthetic process
H1Q64_12165	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
H1Q64_12165	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H1Q64_12170	COG0371	Dehydrogenase
H1Q64_12175	COG1494	fructose-1,6-bisphosphatase
H1Q64_12185	COG0436	Aminotransferase
H1Q64_12190	COG2814	Major facilitator Superfamily
H1Q64_12205	COG3243	poly(R)-hydroxyalkanoic acid synthase
H1Q64_12210	COG2885	chlorophyll binding
H1Q64_12210	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H1Q64_12215	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H1Q64_12220	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
H1Q64_12225	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H1Q64_12230	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
H1Q64_12240	COG1024	Enoyl-CoA hydratase
H1Q64_12245	COG1832	CoA-binding protein
H1Q64_12280	COG2205	protein histidine kinase activity
H1Q64_12310	COG0840	transmembrane signaling receptor activity
H1Q64_12315	COG0745	RESPONSE REGULATOR receiver
H1Q64_12325	COG0745	RESPONSE REGULATOR receiver
H1Q64_12340	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1Q64_12345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1Q64_12365	COG0436	Aminotransferase
H1Q64_12380	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H1Q64_12390	COG0728	peptidoglycan biosynthetic process
H1Q64_12395	COG0596	Alpha beta hydrolase
H1Q64_12425	COG2986	histidine ammonia-lyase
H1Q64_12450	COG0037	tRNA processing
H1Q64_12460	COG0148	phosphopyruvate hydratase activity
H1Q64_12470	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
H1Q64_12475	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
H1Q64_12480	COG0535	radical SAM domain protein
H1Q64_12485	COG0535	radical SAM domain protein
H1Q64_12515	COG0149	triose-phosphate isomerase activity
H1Q64_12525	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H1Q64_12575	COG0315	cyclic pyranopterin monophosphate synthase activity
H1Q64_12580	COG0303	'Molybdopterin
H1Q64_12585	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H1Q64_12590	COG0658	competence protein
H1Q64_12590	COG2333	competence protein COMEC
H1Q64_12595	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H1Q64_12600	COG0372	Belongs to the citrate synthase family
H1Q64_12615	COG0583	DNA-binding transcription factor activity
H1Q64_12630	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H1Q64_12635	COG3494	Protein of unknown function (DUF1009)
H1Q64_12640	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H1Q64_12660	COG0750	zinc metalloprotease
H1Q64_12665	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
H1Q64_12675	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H1Q64_12680	COG0233	cytoplasmic translational termination
H1Q64_12685	COG0528	UMP kinase activity
H1Q64_12690	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
H1Q64_12695	COG0052	Belongs to the universal ribosomal protein uS2 family
H1Q64_12730	COG0442	prolyl-tRNA aminoacylation
H1Q64_12745	COG0519	Catalyzes the synthesis of GMP from XMP
H1Q64_12755	COG0346	lactoylglutathione lyase activity
H1Q64_12775	COG1007	ATP synthesis coupled electron transport
H1Q64_12790	COG0713	ATP synthesis coupled electron transport
H1Q64_12800	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H1Q64_12805	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
H1Q64_12810	COG1034	ATP synthesis coupled electron transport
H1Q64_12820	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
H1Q64_12825	COG0649	NAD binding
H1Q64_12835	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H1Q64_12840	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H1Q64_12890	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H1Q64_12890	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H1Q64_12915	COG0443	Heat shock 70 kDa protein
H1Q64_12920	COG1012	belongs to the aldehyde dehydrogenase family
H1Q64_12920	COG2030	dehydratase
H1Q64_12945	COG0670	Belongs to the BI1 family
H1Q64_12960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1Q64_12965	COG0352	thiamine-phosphate diphosphorylase activity
H1Q64_12965	COG0351	phosphomethylpyrimidine kinase
H1Q64_12970	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H1Q64_12975	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H1Q64_12985	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
H1Q64_12990	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H1Q64_12995	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q64_13010	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
H1Q64_13050	COG1079	Belongs to the binding-protein-dependent transport system permease family
H1Q64_13055	COG4603	Belongs to the binding-protein-dependent transport system permease family
H1Q64_13060	COG3845	ABC transporter
H1Q64_13065	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H1Q64_13070	COG0354	folic acid binding
H1Q64_13090	COG0546	phosphoglycolate phosphatase activity
H1Q64_13095	COG3135	benzoate transporter
H1Q64_13100	COG1802	Transcriptional regulator
H1Q64_13105	COG0564	pseudouridine synthase activity
H1Q64_13110	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
H1Q64_13125	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H1Q64_13140	COG1238	metal cluster binding
H1Q64_13145	COG0203	ribosomal protein L17
H1Q64_13160	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
H1Q64_13165	COG0469	pyruvate kinase activity
H1Q64_13170	COG3852	Histidine kinase
H1Q64_13175	COG1238	metal cluster binding
H1Q64_13180	COG2832	Protein of unknown function (DUF454)
H1Q64_13190	COG0521	Mo-molybdopterin cofactor biosynthetic process
H1Q64_13205	COG0546	phosphoglycolate phosphatase activity
H1Q64_13225	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q64_13245	COG1733	regulation of RNA biosynthetic process
H1Q64_13260	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H1Q64_13265	COG2261	transglycosylase associated protein
H1Q64_13270	COG0784	Response regulator, receiver
H1Q64_13280	COG2135	peptidase activity
H1Q64_13290	COG2199	diguanylate cyclase activity
H1Q64_13290	COG2203	Gaf domain
H1Q64_13290	COG2200	EAL domain
H1Q64_13300	COG0366	Alpha amylase catalytic
H1Q64_13305	COG2326	polyphosphate kinase activity
H1Q64_13315	COG0038	chloride channel
H1Q64_13330	COG0411	ABC transporter
H1Q64_13370	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H1Q64_13375	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q64_13380	COG0625	glutathione transferase activity
H1Q64_13415	COG1640	4-alpha-glucanotransferase
H1Q64_13435	COG0784	Response regulator, receiver
H1Q64_13435	COG2205	protein histidine kinase activity
H1Q64_13460	COG1686	Belongs to the peptidase S11 family
H1Q64_13475	COG1840	ABC-type Fe3 transport system, periplasmic component
H1Q64_13480	COG4149	molybdate abc transporter
H1Q64_13485	COG3842	ATPase activity
H1Q64_13500	COG2391	methyltransferase activity
H1Q64_13510	COG0583	DNA-binding transcription factor activity
H1Q64_13515	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
H1Q64_13520	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
H1Q64_13525	COG2358	TRAP transporter, solute receptor (TAXI family
H1Q64_13550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1Q64_13590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H1Q64_13605	COG0745	RESPONSE REGULATOR receiver
H1Q64_13610	COG0784	Response regulator, receiver
H1Q64_13610	COG2198	Histidine kinase
H1Q64_13610	COG2205	protein histidine kinase activity
H1Q64_13615	COG1278	Cold shock
H1Q64_13625	COG1846	Transcriptional regulator
H1Q64_13630	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H1Q64_13640	COG0556	nucleotide-excision repair
H1Q64_13660	COG2205	protein histidine kinase activity
H1Q64_13665	COG2927	DNA polymerase III (CHI subunit)
H1Q64_13670	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
H1Q64_13700	COG0741	lytic transglycosylase activity
H1Q64_13725	COG1561	YicC-like family, N-terminal region
H1Q64_13730	COG0300	oxidoreductase activity
H1Q64_13735	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H1Q64_13740	COG3932	Exopolysaccharide synthesis, ExoD
H1Q64_13745	COG0488	(ABC) transporter
H1Q64_13750	COG0105	UTP biosynthetic process
H1Q64_13765	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H1Q64_13770	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
H1Q64_13780	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H1Q64_13785	COG0628	permease
H1Q64_13795	COG0300	oxidoreductase activity
H1Q64_13810	COG3025	triphosphatase activity
H1Q64_13820	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
H1Q64_13825	COG0248	Ppx GppA phosphatase
H1Q64_13835	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
H1Q64_13840	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
H1Q64_13860	COG5002	protein histidine kinase activity
H1Q64_13860	COG3447	MASE1 domain protein
H1Q64_13860	COG5001	Diguanylate cyclase
H1Q64_13865	COG2202	Pas domain
H1Q64_13865	COG2205	protein histidine kinase activity
H1Q64_13870	COG0784	Response regulator, receiver
H1Q64_13880	COG0267	Belongs to the bacterial ribosomal protein bL33 family
H1Q64_13885	COG0793	Belongs to the peptidase S41A family
H1Q64_13890	COG0557	exoribonuclease II activity
H1Q64_13915	COG0357	Ribosomal RNA small subunit methyltransferase G
H1Q64_13915	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H1Q64_13920	COG3813	Protein conserved in bacteria
H1Q64_13955	COG1247	-acetyltransferase
H1Q64_13960	COG0519	Catalyzes the synthesis of GMP from XMP
H1Q64_13970	COG3436	PFAM IS66 Orf2 family protein
H1Q64_14045	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H1Q64_14055	COG1136	(ABC) transporter
H1Q64_14065	COG4245	von Willebrand factor, type A
H1Q64_14190	COG1397	ADP-ribosylglycohydrolase
H1Q64_14200	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
H1Q64_14240	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H1Q64_14250	COG1397	ADP-ribosylglycohydrolase
H1Q64_14285	COG2963	transposase activity
H1Q64_14290	COG3436	PFAM IS66 Orf2 family protein
H1Q64_14305	COG3436	PFAM IS66 Orf2 family protein
H1Q64_14310	COG2433	Pfam Transposase IS66
H1Q64_14320	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H1Q64_14335	COG3547	Transposase (IS116 IS110 IS902 family)
H1Q64_14345	COG0720	synthase
H1Q64_14350	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H1Q64_14355	COG0602	queuosine metabolic process
H1Q64_14380	COG3547	Transposase (IS116 IS110 IS902 family)
H1Q64_14420	COG0514	ATP-dependent DNA helicase (RecQ)
H1Q64_14435	COG3335	DDE superfamily endonuclease
H1Q64_14560	COG0714	Associated with various cellular activities
H1Q64_14580	COG0617	tRNA 3'-terminal CCA addition
H1Q64_14585	COG0408	coproporphyrinogen oxidase activity
H1Q64_14590	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H1Q64_14605	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
H1Q64_14605	COG2857	Cytochrome c1
H1Q64_14625	COG0640	Transcriptional regulator
H1Q64_14630	COG0425	Belongs to the sulfur carrier protein TusA family
H1Q64_14640	COG1722	exodeoxyribonuclease VII activity
H1Q64_14650	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
H1Q64_14660	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
H1Q64_14685	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
H1Q64_14690	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1Q64_14700	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
H1Q64_14705	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H1Q64_14715	COG0657	acetylesterase activity
H1Q64_14750	COG3264	Mechanosensitive ion channel
H1Q64_14750	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
H1Q64_14765	COG0386	Belongs to the glutathione peroxidase family
H1Q64_14775	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H1Q64_14785	COG1737	Transcriptional regulator
H1Q64_14785	COG0837	glucose binding
H1Q64_14790	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
H1Q64_14795	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
H1Q64_14800	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H1Q64_14810	COG0179	Fumarylacetoacetate (FAA) hydrolase
H1Q64_14825	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H1Q64_14830	COG0758	DNA mediated transformation
H1Q64_14850	COG2814	Major facilitator Superfamily
H1Q64_14880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1Q64_14880	COG2205	protein histidine kinase activity
H1Q64_14885	COG0745	RESPONSE REGULATOR receiver
H1Q64_14920	COG0581	inorganic phosphate transmembrane transporter activity
H1Q64_14935	COG3842	ATPase activity
H1Q64_14945	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
H1Q64_14950	COG1732	Glycine betaine
H1Q64_14955	COG1174	glycine betaine transport
H1Q64_14960	COG1125	glycine betaine transport
H1Q64_14965	COG1174	glycine betaine transport
H1Q64_14975	COG1652	LysM domain
H1Q64_14980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H1Q64_14990	COG1024	Enoyl-CoA hydratase
H1Q64_14995	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
H1Q64_15000	COG1609	Transcriptional regulator
H1Q64_15005	COG3265	gluconokinase activity
H1Q64_15015	COG3971	2-oxopent-4-enoate hydratase activity
H1Q64_15020	COG1609	Transcriptional regulator
H1Q64_15025	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H1Q64_15030	COG1126	abc transporter atp-binding protein
H1Q64_15035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1Q64_15040	COG0765	amino acid transport
H1Q64_15045	COG0765	amino acid transport
H1Q64_15070	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q64_15075	COG0730	response to heat
H1Q64_15090	COG0717	Belongs to the dCTP deaminase family
H1Q64_15095	COG2188	Transcriptional regulator
H1Q64_15100	COG0683	leucine binding
H1Q64_15150	COG1053	succinate dehydrogenase
H1Q64_15155	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
H1Q64_15160	COG0066	3-isopropylmalate dehydratase activity
H1Q64_15180	COG0708	Exodeoxyribonuclease III
H1Q64_15185	COG0316	Belongs to the HesB IscA family
H1Q64_15190	COG0232	Belongs to the dGTPase family. Type 2 subfamily
H1Q64_15205	COG1472	Belongs to the glycosyl hydrolase 3 family
H1Q64_15210	COG1994	Peptidase M50
H1Q64_15215	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
H1Q64_15220	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H1Q64_15225	COG3842	ATPase activity
H1Q64_15230	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H1Q64_15235	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H1Q64_15240	COG0805	protein transport
H1Q64_15250	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
H1Q64_15260	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
H1Q64_15280	COG1862	Preprotein translocase
H1Q64_15285	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H1Q64_15295	COG3737	Protein of unknown function (DUF498/DUF598)
H1Q64_15305	COG1233	COG1233 Phytoene dehydrogenase and related
H1Q64_15310	COG1562	ergosterol biosynthetic process
H1Q64_15315	COG1562	ergosterol biosynthetic process
H1Q64_15330	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
H1Q64_15345	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H1Q64_15350	COG0629	single-stranded DNA binding
H1Q64_15420	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H1Q64_15485	COG0534	Mate efflux family protein
H1Q64_15490	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H1Q64_15495	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
H1Q64_15530	COG0129	dihydroxy-acid dehydratase activity
H1Q64_15540	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H1Q64_15560	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H1Q64_15565	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H1Q64_15580	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H1Q64_15585	COG3383	formate dehydrogenase (NAD+) activity
H1Q64_15600	COG0583	DNA-binding transcription factor activity
H1Q64_15615	COG0697	spore germination
H1Q64_15620	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
H1Q64_15660	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H1Q64_15680	COG0308	aminopeptidase N
H1Q64_15690	COG0316	Belongs to the HesB IscA family
H1Q64_15700	COG0822	iron-sulfur transferase activity
H1Q64_15705	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H1Q64_15710	COG0719	Fe-S assembly protein
H1Q64_15715	COG0396	ATPase activity
H1Q64_15720	COG0719	Fe-S assembly protein
H1Q64_15725	COG1959	2 iron, 2 sulfur cluster binding
H1Q64_15755	COG0745	RESPONSE REGULATOR receiver
H1Q64_15760	COG5002	protein histidine kinase activity
H1Q64_15805	COG0058	SHG alpha-glucan phosphorylase activity
H1Q64_15810	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H1Q64_15815	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
H1Q64_15830	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
H1Q64_15835	COG1984	allophanate hydrolase subunit 2
H1Q64_15840	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
H1Q64_15845	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
H1Q64_15860	COG4336	lyase activity
H1Q64_15865	COG0583	DNA-binding transcription factor activity
H1Q64_15875	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1Q64_15910	COG0840	transmembrane signaling receptor activity
H1Q64_15935	COG0366	Alpha amylase catalytic
H1Q64_15940	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
H1Q64_15945	COG0625	glutathione transferase activity
H1Q64_15950	COG4166	transmembrane transport
H1Q64_15965	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H1Q64_15970	COG0393	Putative heavy-metal-binding
H1Q64_16000	COG1280	lysine exporter protein (LysE YggA)
H1Q64_16010	COG2183	response to ionizing radiation
H1Q64_16015	COG0651	ATP synthesis coupled electron transport
H1Q64_16020	COG0650	Formate hydrogenlyase subunit 4
H1Q64_16030	COG0651	ATP synthesis coupled electron transport
H1Q64_16035	COG0649	NAD binding
H1Q64_16040	COG3260	NADH ubiquinone oxidoreductase 20
H1Q64_16045	COG3956	TIGRFAM MazG family protein
H1Q64_16060	COG0483	inositol monophosphate 1-phosphatase activity
H1Q64_16075	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H1Q64_16080	COG1923	regulation of RNA biosynthetic process
H1Q64_16095	COG0569	domain protein
H1Q64_16105	COG2204	response regulator
H1Q64_16140	COG1058	Belongs to the CinA family
H1Q64_16140	COG1546	Belongs to the CinA family
H1Q64_16145	COG2867	negative regulation of translational initiation
H1Q64_16150	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H1Q64_16155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1Q64_16160	COG0508	dehydrogenase complex catalyzes the overall conversion of
H1Q64_16165	COG0022	dehydrogenase e1 component
H1Q64_16165	COG0508	dehydrogenase complex catalyzes the overall conversion of
H1Q64_16170	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H1Q64_16175	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H1Q64_16180	COG1607	acyl-coa hydrolase
H1Q64_16185	COG0187	DNA topoisomerase II activity
H1Q64_16205	COG0513	Belongs to the DEAD box helicase family
H1Q64_16250	COG2815	serine threonine protein kinase
H1Q64_16250	COG0515	serine threonine protein kinase
H1Q64_16255	COG2017	converts alpha-aldose to the beta-anomer
H1Q64_16275	COG2308	Evidence 4 Homologs of previously reported genes of
H1Q64_16275	COG2307	Protein conserved in bacteria
H1Q64_16285	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1Q64_16290	COG1566	PFAM secretion protein HlyD family protein
H1Q64_16300	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H1Q64_16305	COG1215	transferase activity, transferring glycosyl groups
H1Q64_16310	COG0740	serine-type endopeptidase activity
H1Q64_16330	COG3768	UPF0283 membrane protein
H1Q64_16335	COG3106	COG3106 Predicted ATPase
H1Q64_16340	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H1Q64_16345	COG0571	ribonuclease III activity
H1Q64_16350	COG0681	Belongs to the peptidase S26 family
H1Q64_16355	COG0736	holo-[acyl-carrier-protein] synthase activity
H1Q64_16360	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
H1Q64_16375	COG1758	RNA polymerase activity
H1Q64_16390	COG3920	Histidine kinase
H1Q64_16400	COG1846	Transcriptional regulator
H1Q64_16410	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
H1Q64_16420	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
H1Q64_16435	COG3240	lipase activity
H1Q64_16440	COG3038	cytochrome b561
H1Q64_16450	COG0501	Belongs to the peptidase M48B family
H1Q64_16455	COG0484	heat shock protein binding
H1Q64_16470	COG0492	ferredoxin-NADP+ reductase activity
H1Q64_16480	COG2197	response regulator
H1Q64_16490	COG0435	Glutathione S-transferase
H1Q64_16495	COG0655	NAD(P)H dehydrogenase (quinone) activity
H1Q64_16500	COG0583	DNA-binding transcription factor activity
H1Q64_16515	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H1Q64_16540	COG4191	Histidine kinase
H1Q64_16545	COG1132	(ABC) transporter
H1Q64_16550	COG1752	Esterase of the alpha-beta hydrolase superfamily
H1Q64_16580	COG5001	Diguanylate cyclase
H1Q64_16605	COG1666	GTP binding
H1Q64_16635	COG4608	Belongs to the ABC transporter superfamily
H1Q64_16640	COG0444	Belongs to the ABC transporter superfamily
H1Q64_16645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H1Q64_16650	COG0601	transmembrane transport
H1Q64_16655	COG0747	negative chemotaxis
H1Q64_16670	COG2226	methyltransferase
H1Q64_16685	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
H1Q64_16700	COG1228	amidohydrolase
H1Q64_16710	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H1Q64_16735	COG0784	Response regulator, receiver
H1Q64_16790	COG0859	PFAM glycosyl transferase family 9
H1Q64_16790	COG0457	Tetratricopeptide repeat
H1Q64_16800	COG0859	PFAM glycosyl transferase family 9
H1Q64_16800	COG0457	Tetratricopeptide repeat
H1Q64_16820	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H1Q64_16825	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q64_16850	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
H1Q64_16855	COG2089	acid synthase
H1Q64_16880	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q64_16895	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q64_16910	COG1294	oxidase, subunit
H1Q64_16915	COG1271	oxidase subunit
H1Q64_16920	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H1Q64_16940	COG1127	ABC transporter
H1Q64_16945	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H1Q64_16950	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
H1Q64_16965	COG2703	oxygen carrier activity
H1Q64_17000	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H1Q64_17005	COG0583	DNA-binding transcription factor activity
H1Q64_17010	COG0667	Aldo Keto reductase
H1Q64_17045	COG1401	restriction endodeoxyribonuclease activity
H1Q64_17075	COG4566	intracellular signal transduction
H1Q64_17080	COG4191	Histidine kinase
H1Q64_17095	COG2814	Major facilitator Superfamily
H1Q64_17100	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
H1Q64_17120	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H1Q64_17130	COG0583	DNA-binding transcription factor activity
H1Q64_17135	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q64_17170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1Q64_17175	COG0477	Major facilitator Superfamily
H1Q64_17180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1Q64_17190	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
H1Q64_17340	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
H1Q64_17500	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H1Q64_17505	COG3806	Anti-sigma factor
H1Q64_17510	COG1595	DNA-templated transcription, initiation
H1Q64_17520	COG1882	Formate acetyltransferase
H1Q64_17530	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H1Q64_17530	COG3008	intermembrane lipid transfer
H1Q64_17535	COG2995	paraquat-inducible protein a
H1Q64_17545	COG0457	Tetratricopeptide repeat
H1Q64_17545	COG0859	PFAM glycosyl transferase family 9
H1Q64_17550	COG0281	malic enzyme
H1Q64_17550	COG0280	phosphate acetyltransferase
H1Q64_17555	COG1301	dicarboxylic acid transport
H1Q64_17560	COG4191	Histidine kinase
H1Q64_17565	COG2204	response regulator
H1Q64_17590	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
H1Q64_17590	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
H1Q64_17595	COG1268	BioY protein
H1Q64_17600	COG4770	biotin carboxylase activity
H1Q64_17605	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H1Q64_17610	COG1396	sequence-specific DNA binding
H1Q64_17610	COG3800	Transcriptional regulator
H1Q64_17615	COG1794	racemase activity, acting on amino acids and derivatives
H1Q64_17645	COG1228	amidohydrolase
H1Q64_17670	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1Q64_17680	COG2814	Major facilitator Superfamily
H1Q64_17690	COG0583	DNA-binding transcription factor activity
H1Q64_17730	COG0318	PFAM AMP-dependent synthetase and ligase
H1Q64_17735	COG0604	alcohol dehydrogenase
H1Q64_17740	COG3547	Transposase (IS116 IS110 IS902 family)
H1Q64_17770	COG0583	DNA-binding transcription factor activity
H1Q64_17780	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q64_17785	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H1Q64_17790	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
H1Q64_17800	COG1252	NADH dehydrogenase
H1Q64_17815	COG0583	DNA-binding transcription factor activity
H1Q64_17825	COG3220	belongs to the UPF0276 family
H1Q64_17940	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H1Q64_17945	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H1Q64_18025	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H1Q64_18135	COG0582	viral genome integration into host DNA
H1Q64_18440	COG1061	Type III restriction enzyme res subunit
H1Q64_18490	COG1396	sequence-specific DNA binding
H1Q64_18550	COG3723	Recombinational DNA repair protein, rece pathway
H1Q64_18640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1Q64_18640	COG4191	Histidine kinase
H1Q64_18645	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H1Q64_18650	COG0154	amidase activity
H1Q64_18655	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H1Q64_18670	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H1Q64_18690	COG0583	DNA-binding transcription factor activity
H1Q64_18705	COG0540	Belongs to the ATCase OTCase family
H1Q64_18710	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
H1Q64_18720	COG0745	RESPONSE REGULATOR receiver
H1Q64_18740	COG1988	membrane-bound metal-dependent
H1Q64_18750	COG2080	2 iron, 2 sulfur cluster binding
H1Q64_18755	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
H1Q64_18760	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H1Q64_18765	COG3634	alkyl hydroperoxide reductase activity
H1Q64_18775	COG0583	DNA-binding transcription factor activity
H1Q64_18785	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H1Q64_18790	COG0287	Prephenate dehydrogenase
H1Q64_18795	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H1Q64_18805	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H1Q64_18810	COG2813	Specifically methylates the guanine in position
H1Q64_18810	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H1Q64_18830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1Q64_18835	COG0625	glutathione transferase activity
H1Q64_18850	COG2226	methyltransferase
H1Q64_18860	COG2267	carboxylic ester hydrolase activity
H1Q64_18865	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H1Q64_18880	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
H1Q64_18900	COG0583	DNA-binding transcription factor activity
H1Q64_18935	COG0583	DNA-binding transcription factor activity
H1Q64_18990	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
H1Q64_19005	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
H1Q64_19010	COG0437	4 iron, 4 sulfur cluster binding
H1Q64_19015	COG5557	Pfam Polysulphide reductase, NrfD
H1Q64_19020	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
H1Q64_19025	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
H1Q64_19030	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
H1Q64_19040	COG0298	carbon dioxide binding
H1Q64_19055	COG0375	protein maturation
H1Q64_19065	COG1280	lysine exporter protein (LysE YggA)
H1Q64_19070	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
H1Q64_19080	COG0309	Hydrogenase expression formation protein (HypE)
H1Q64_19090	COG0793	Belongs to the peptidase S41A family
H1Q64_19095	COG1278	Cold shock
H1Q64_19100	COG3012	SEC-C Motif Domain Protein
H1Q64_19105	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H1Q64_19105	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1Q64_19115	COG2189	Belongs to the N(4) N(6)-methyltransferase family
H1Q64_19135	COG1194	a g-specific adenine glycosylase
H1Q64_19150	COG1196	nuclear chromosome segregation
H1Q64_19165	COG3047	cAMP biosynthetic process
H1Q64_19180	COG1960	acyl-CoA dehydrogenase activity
H1Q64_19185	COG1250	3-hydroxyacyl-CoA dehydrogenase
H1Q64_19185	COG1024	Enoyl-CoA hydratase
H1Q64_19190	COG0183	Belongs to the thiolase family
H1Q64_19205	COG2373	Large extracellular alpha-helical protein
H1Q64_19210	COG2205	protein histidine kinase activity
H1Q64_19215	COG0436	Aminotransferase
H1Q64_19220	COG1396	sequence-specific DNA binding
H1Q64_19225	COG1766	The M ring may be actively involved in energy transduction
H1Q64_19235	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H1Q64_19240	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
H1Q64_19245	COG2204	response regulator
H1Q64_19250	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H1Q64_19255	COG0552	protein localization to endoplasmic reticulum
H1Q64_19270	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
H1Q64_19290	COG0745	RESPONSE REGULATOR receiver
H1Q64_19300	COG0583	DNA-binding transcription factor activity
H1Q64_19315	COG0643	Histidine kinase
H1Q64_19315	COG2198	Histidine kinase
H1Q64_19315	COG0784	Response regulator, receiver
H1Q64_19320	COG0835	chemotaxis
H1Q64_19325	COG0643	Histidine kinase
H1Q64_19325	COG2198	Histidine kinase
H1Q64_19325	COG0784	Response regulator, receiver
H1Q64_19350	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H1Q64_19355	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1Q64_19360	COG1360	Flagellar Motor Protein
H1Q64_19365	COG2308	Evidence 4 Homologs of previously reported genes of
H1Q64_19385	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
H1Q64_19385	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
H1Q64_19390	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
H1Q64_19395	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H1Q64_19400	COG1381	Involved in DNA repair and RecF pathway recombination
H1Q64_19405	COG5001	Diguanylate cyclase
H1Q64_19440	COG2884	Cell division ATP-binding protein ftsE
H1Q64_19470	COG0586	Pfam SNARE associated Golgi protein
H1Q64_19475	COG0505	Belongs to the CarA family
H1Q64_19485	COG3135	benzoate transporter
H1Q64_19490	COG0583	DNA-binding transcription factor activity
H1Q64_19495	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1Q64_19510	COG0488	(ABC) transporter
H1Q64_19520	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
H1Q64_19525	COG0409	Hydrogenase expression formation protein
H1Q64_19545	COG2217	Heavy metal translocating P-type atpase
H1Q64_19570	COG1741	Belongs to the pirin family
H1Q64_19575	COG2860	membrane
H1Q64_19585	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H1Q64_19590	COG0789	Transcriptional regulator
H1Q64_19605	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H1Q64_19610	COG4520	surface antigen
H1Q64_19650	COG1566	PFAM secretion protein HlyD family protein
H1Q64_19660	COG0583	DNA-binding transcription factor activity
H1Q64_19665	COG2814	Major facilitator Superfamily
H1Q64_19675	COG3273	potassium ion transport
H1Q64_19675	COG0471	metal ion transport
H1Q64_19705	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H1Q64_19715	COG0583	DNA-binding transcription factor activity
H1Q64_19720	COG3842	ATPase activity
H1Q64_19725	COG2182	Extracellular solute-binding protein
H1Q64_19730	COG1176	ABC-type spermidine putrescine transport system, permease component I
H1Q64_19740	COG1917	Cupin 2, conserved barrel domain protein
H1Q64_19740	COG1396	sequence-specific DNA binding
H1Q64_19750	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H1Q64_19760	COG5507	3-demethylubiquinone-9 3-methyltransferase
H1Q64_19775	COG1309	transcriptional regulator
H1Q64_19790	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H1Q64_19800	COG1522	sequence-specific DNA binding
H1Q64_19805	COG1192	Involved in chromosome partitioning
H1Q64_19835	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
H1Q64_19840	COG1530	ribonuclease E activity
H1Q64_19850	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
H1Q64_19865	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H1Q64_19875	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H1Q64_19895	COG0318	PFAM AMP-dependent synthetase and ligase
H1Q64_19900	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H1Q64_19905	COG2011	ABC-type metal ion transport system permease component
H1Q64_19920	COG5002	protein histidine kinase activity
H1Q64_19945	COG0588	phosphoglycerate mutase activity
H1Q64_19950	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H1Q64_19955	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
H1Q64_19965	COG3693	PFAM glycoside hydrolase, family 10
H1Q64_19975	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
H1Q64_19995	COG1215	transferase activity, transferring glycosyl groups
H1Q64_20000	COG0438	transferase activity, transferring glycosyl groups
H1Q64_20005	COG0438	transferase activity, transferring glycosyl groups
H1Q64_20020	COG0318	PFAM AMP-dependent synthetase and ligase
H1Q64_20025	COG0367	asparagine synthase
H1Q64_20030	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H1Q64_20055	COG0745	RESPONSE REGULATOR receiver
H1Q64_20075	COG4208	sulfate ABC transporter
H1Q64_20085	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H1Q64_20100	COG1959	2 iron, 2 sulfur cluster binding
H1Q64_20105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1Q64_20120	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
H1Q64_20125	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H1Q64_20155	COG3685	Protein conserved in bacteria
H1Q64_20205	COG4206	TonB-dependent receptor
H1Q64_20215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1Q64_20250	COG1695	Transcriptional regulator
H1Q64_20255	COG4607	ABC-type enterochelin transport system periplasmic component
H1Q64_20260	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1Q64_20265	COG4605	iron ion homeostasis
H1Q64_20270	COG4604	ABC transporter, ATP-binding protein
H1Q64_20285	COG3128	pkhd-type hydroxylase
H1Q64_20295	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H1Q64_20310	COG0671	phosphoesterase, PA-phosphatase related
H1Q64_20315	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
H1Q64_20330	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
H1Q64_20335	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H1Q64_20340	COG0842	Transport permease protein
H1Q64_20345	COG2137	regulation of response to DNA damage stimulus
H1Q64_20355	COG0227	Belongs to the bacterial ribosomal protein bL28 family
H1Q64_20365	COG1703	isobutyryl-CoA mutase activity
H1Q64_20375	COG5265	(ABC) transporter
H1Q64_20380	COG0840	transmembrane signaling receptor activity
H1Q64_20395	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H1Q64_20405	COG1272	protein, Hemolysin III
H1Q64_20410	COG0542	response to heat
H1Q64_20430	COG2890	protein-(glutamine-N5) methyltransferase activity
H1Q64_20435	COG2852	Protein conserved in bacteria
H1Q64_20445	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
H1Q64_20450	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
H1Q64_20465	COG2070	2-Nitropropane dioxygenase
H1Q64_20470	COG0527	aspartate kinase activity
H1Q64_20475	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H1Q64_20480	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1Q64_20485	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
H1Q64_20490	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
H1Q64_20495	COG1137	ATPase activity
H1Q64_20530	COG2223	nitrite transmembrane transporter activity
H1Q64_20550	COG1214	PFAM Peptidase M22, glycoprotease
H1Q64_20550	COG0456	acetyltransferase
H1Q64_20610	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q64_20620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1Q64_20625	COG1116	anion transmembrane transporter activity
H1Q64_20645	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H1Q64_20650	COG2864	formate dehydrogenase
H1Q64_20655	COG0437	4 iron, 4 sulfur cluster binding
H1Q64_20660	COG0243	molybdopterin cofactor binding
H1Q64_20660	COG3383	formate dehydrogenase (NAD+) activity
H1Q64_20700	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
H1Q64_20725	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H1Q64_20735	COG3648	Uricase
H1Q64_20735	COG3195	allantoin biosynthetic process
H1Q64_20750	COG0583	DNA-binding transcription factor activity
H1Q64_20755	COG1609	Transcriptional regulator
H1Q64_20810	COG0791	NLP P60 protein
H1Q64_20815	COG1648	precorrin-2 dehydrogenase activity
H1Q64_20815	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H1Q64_20820	COG0243	molybdopterin cofactor binding
H1Q64_20825	COG2146	nitrite reductase [NAD(P)H] activity
H1Q64_20830	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1Q64_20835	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1Q64_20845	COG1116	anion transmembrane transporter activity
H1Q64_20850	COG3707	response regulator
H1Q64_20855	COG0251	oxidation-reduction process
H1Q64_20860	COG0583	DNA-binding transcription factor activity
H1Q64_20875	COG1475	DNA binding
H1Q64_20880	COG1192	Involved in chromosome partitioning
H1Q64_20890	COG3591	Belongs to the peptidase S1B family
H1Q64_20900	COG0420	3'-5' exonuclease activity
H1Q64_20940	COG1942	4-Oxalocrotonate Tautomerase
H1Q64_20945	COG0235	Class ii aldolase
H1Q64_20955	COG4191	Histidine kinase
H1Q64_20960	COG3058	Necessary for formate dehydrogenase activity
H1Q64_20965	COG0243	molybdopterin cofactor binding
H1Q64_20965	COG3383	formate dehydrogenase (NAD+) activity
H1Q64_20970	COG0437	4 iron, 4 sulfur cluster binding
H1Q64_20975	COG2864	formate dehydrogenase
H1Q64_20980	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H1Q64_20985	COG2205	protein histidine kinase activity
H1Q64_21005	COG0840	transmembrane signaling receptor activity
H1Q64_21015	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
H1Q64_21025	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
H1Q64_21055	COG2027	D-alanyl-D-alanine carboxypeptidase
H1Q64_21065	COG2091	lysine biosynthetic process via aminoadipic acid
H1Q64_21070	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
H1Q64_21075	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H1Q64_21085	COG2111	Na H antiporter
H1Q64_21085	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H1Q64_21090	COG1006	Multisubunit Na H antiporter MnhC subunit
H1Q64_21095	COG0651	ATP synthesis coupled electron transport
H1Q64_21100	COG1863	multisubunit Na H antiporter MnhE subunit
H1Q64_21105	COG2212	antiporter activity
H1Q64_21110	COG1320	monovalent cation:proton antiporter activity
H1Q64_21150	COG4615	Cyclic peptide transporter
H1Q64_21190	COG0683	leucine binding
H1Q64_21220	COG3842	ATPase activity
H1Q64_21230	COG1175	transmembrane transport
H1Q64_21250	COG1024	Enoyl-CoA hydratase
H1Q64_21270	COG1609	Transcriptional regulator
H1Q64_21300	COG1966	Carbon starvation protein
H1Q64_21305	COG2879	small protein
H1Q64_21320	COG4221	oxidoreductase activity
H1Q64_21335	COG0765	amino acid transport
H1Q64_21340	COG0765	amino acid transport
H1Q64_21370	COG0840	transmembrane signaling receptor activity
H1Q64_21375	COG2423	ornithine cyclodeaminase activity
H1Q64_21380	COG0657	acetylesterase activity
H1Q64_21415	COG2814	Major facilitator Superfamily
H1Q64_21420	COG0583	DNA-binding transcription factor activity
H1Q64_21430	COG4774	siderophore transport
H1Q64_21435	COG1120	ATPase activity
H1Q64_21450	COG1132	(ABC) transporter
H1Q64_21515	COG1764	response to oxidative stress
H1Q64_21520	COG1846	Transcriptional regulator
H1Q64_21525	COG0583	DNA-binding transcription factor activity
H1Q64_21530	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q64_21545	COG2860	membrane
H1Q64_21550	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H1Q64_21555	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H1Q64_21570	COG3246	L-lysine catabolic process to acetate
H1Q64_21595	COG4638	Rieske (2fe-2S)
H1Q64_21635	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
H1Q64_21675	COG4566	intracellular signal transduction
H1Q64_21680	COG4191	Histidine kinase
H1Q64_21685	COG1335	isochorismatase
H1Q64_21750	COG0625	glutathione transferase activity
H1Q64_21755	COG0583	DNA-binding transcription factor activity
H1Q64_21760	COG4948	Mandelate Racemase Muconate Lactonizing
H1Q64_21770	COG0288	reversible hydration of carbon dioxide
H1Q64_21780	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H1Q64_21805	COG0438	transferase activity, transferring glycosyl groups
H1Q64_21845	COG1960	acyl-CoA dehydrogenase activity
H1Q64_21855	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
H1Q64_21870	COG0583	DNA-binding transcription factor activity
H1Q64_21875	COG2080	2 iron, 2 sulfur cluster binding
H1Q64_21880	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
H1Q64_21900	COG1280	lysine exporter protein (LysE YggA)
H1Q64_21920	COG0521	Mo-molybdopterin cofactor biosynthetic process
H1Q64_21925	COG0741	lytic transglycosylase activity
H1Q64_21930	COG1573	uracil-dna glycosylase
H1Q64_21955	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1Q64_22005	COG4520	surface antigen
H1Q64_22050	COG2900	Belongs to the SlyX family
H1Q64_22070	COG0583	DNA-binding transcription factor activity
H1Q64_22080	COG1283	sodium-dependent phosphate transmembrane transporter activity
H1Q64_22105	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1Q64_22140	COG0306	phosphate transporter
H1Q64_22145	COG1392	Phosphate transport regulator
H1Q64_22155	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H1Q64_22175	COG0716	FMN binding
H1Q64_22180	COG2223	nitrite transmembrane transporter activity
H1Q64_22215	COG0612	Peptidase, M16
H1Q64_22225	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
H1Q64_22230	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H1Q64_22255	COG1657	PFAM Prenyltransferase squalene oxidase
H1Q64_22275	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
H1Q64_22280	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
H1Q64_22295	COG2205	protein histidine kinase activity
H1Q64_22305	COG1253	flavin adenine dinucleotide binding
H1Q64_22310	COG0772	Belongs to the SEDS family
H1Q64_22330	COG0019	diaminopimelate decarboxylase activity
H1Q64_22345	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H1Q64_22350	COG1073	alpha beta
H1Q64_22360	COG1250	3-hydroxyacyl-CoA dehydrogenase
H1Q64_22370	COG2086	electron transfer activity
H1Q64_22385	COG2723	6-phospho-beta-galactosidase activity
H1Q64_22415	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H1Q64_22450	COG1137	ATPase activity
H1Q64_22455	COG0840	transmembrane signaling receptor activity
H1Q64_22460	COG0795	lipopolysaccharide-transporting ATPase activity
H1Q64_22485	COG1749	Flagellar hook protein flgE
H1Q64_22510	COG0737	Belongs to the 5'-nucleotidase family
H1Q64_22515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1Q64_22520	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H1Q64_22525	COG1309	transcriptional regulator
H1Q64_22530	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q64_22535	COG0778	Nitroreductase
H1Q64_22540	COG1797	cobyrinic acid a,c-diamide synthase activity
H1Q64_22570	COG2099	Precorrin-6x reductase
H1Q64_22630	COG3842	ATPase activity
H1Q64_22635	COG1012	belongs to the aldehyde dehydrogenase family
H1Q64_22645	COG0028	Belongs to the TPP enzyme family
H1Q64_22650	COG1942	4-Oxalocrotonate Tautomerase
H1Q64_22695	COG4948	Mandelate Racemase Muconate Lactonizing
H1Q64_22710	COG1024	Enoyl-CoA hydratase
H1Q64_22715	COG0842	Transport permease protein
H1Q64_22720	COG0842	Transport permease protein
H1Q64_22720	COG1129	ABC transporter
H1Q64_22725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1Q64_22730	COG1940	carbohydrate kinase activity
H1Q64_22740	COG1172	Belongs to the binding-protein-dependent transport system permease family
H1Q64_22745	COG1879	ABC-type sugar transport system periplasmic component
H1Q64_22755	COG0673	inositol 2-dehydrogenase activity
H1Q64_22760	COG2115	Belongs to the xylose isomerase family
H1Q64_22765	COG1070	Carbohydrate kinase
H1Q64_22770	COG0583	DNA-binding transcription factor activity
H1Q64_22780	COG1017	nitric oxide dioxygenase activity
H1Q64_22780	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1Q64_22785	COG0625	glutathione transferase activity
H1Q64_22790	COG1802	Transcriptional regulator
H1Q64_22795	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H1Q64_22800	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H1Q64_22830	COG2197	response regulator
H1Q64_22845	COG3842	ATPase activity
H1Q64_22850	COG1176	ABC-type spermidine putrescine transport system, permease component I
H1Q64_22855	COG1176	ABC-type spermidine putrescine transport system, permease component I
H1Q64_22860	COG3938	Belongs to the proline racemase family
H1Q64_22865	COG1802	Transcriptional regulator
H1Q64_22875	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
H1Q64_22880	COG0066	3-isopropylmalate dehydratase activity
H1Q64_22890	COG1116	anion transmembrane transporter activity
H1Q64_22895	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1Q64_23010	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q64_23025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1Q64_23035	COG1024	Enoyl-CoA hydratase
H1Q64_23040	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H1Q64_23045	COG0154	amidase activity
H1Q64_23075	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q64_23090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1Q64_23105	COG1733	regulation of RNA biosynthetic process
H1Q64_23110	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q64_23130	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
H1Q64_23175	COG3243	poly(R)-hydroxyalkanoic acid synthase
H1Q64_23190	COG0583	DNA-binding transcription factor activity
H1Q64_23205	COG2995	paraquat-inducible protein a
H1Q64_23215	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H1Q64_23215	COG3008	intermembrane lipid transfer
H1Q64_23245	COG0583	DNA-binding transcription factor activity
H1Q64_23255	COG0861	Integral membrane protein TerC family
H1Q64_23270	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
H1Q64_23270	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
H1Q64_23275	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H1Q64_23280	COG3250	beta-galactosidase activity
H1Q64_23295	COG0583	DNA-binding transcription factor activity
H1Q64_23305	COG2084	Dehydrogenase
H1Q64_23310	COG0300	oxidoreductase activity
H1Q64_23360	COG2217	Heavy metal translocating P-type atpase
H1Q64_23405	COG1024	Enoyl-CoA hydratase
H1Q64_23410	COG0318	PFAM AMP-dependent synthetase and ligase
H1Q64_23420	COG1176	ABC-type spermidine putrescine transport system, permease component I
H1Q64_23430	COG3842	ATPase activity
H1Q64_23440	COG0745	RESPONSE REGULATOR receiver
H1Q64_23445	COG5002	protein histidine kinase activity
H1Q64_23445	COG0784	Response regulator, receiver
H1Q64_23450	COG2010	Cytochrome c
H1Q64_23465	COG1309	transcriptional regulator
H1Q64_23470	COG0604	alcohol dehydrogenase
H1Q64_23500	COG0667	Aldo Keto reductase
H1Q64_23535	COG0798	PFAM Bile acid sodium symporter
H1Q64_23540	COG0431	NADPH-dependent FMN reductase
H1Q64_23570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1Q64_23570	COG3321	synthase
H1Q64_23570	COG0604	alcohol dehydrogenase
H1Q64_23570	COG4221	oxidoreductase activity
H1Q64_23585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1Q64_23600	COG0673	inositol 2-dehydrogenase activity
H1Q64_23610	COG0604	alcohol dehydrogenase
H1Q64_23610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1Q64_23610	COG3321	synthase
H1Q64_23610	COG4221	oxidoreductase activity
H1Q64_23625	COG1116	anion transmembrane transporter activity
H1Q64_23670	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
H1Q64_23695	COG1595	DNA-templated transcription, initiation
H1Q64_23700	COG3712	iron ion homeostasis
H1Q64_23710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1Q64_23715	COG0577	efflux transmembrane transporter activity
H1Q64_23715	COG1136	(ABC) transporter
H1Q64_23720	COG0251	oxidation-reduction process
H1Q64_23730	COG0251	oxidation-reduction process
H1Q64_23735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H1Q64_23755	COG1177	transmembrane transport
H1Q64_23760	COG1176	ABC-type spermidine putrescine transport system, permease component I
H1Q64_23765	COG3842	ATPase activity
H1Q64_23780	COG1126	abc transporter atp-binding protein
H1Q64_23785	COG0765	amino acid transport
H1Q64_23795	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H1Q64_23805	COG0277	FAD linked oxidase domain protein
H1Q64_23810	COG1396	sequence-specific DNA binding
H1Q64_23820	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q64_23825	COG3246	L-lysine catabolic process to acetate
H1Q64_23830	COG1250	3-hydroxyacyl-CoA dehydrogenase
H1Q64_23835	COG2204	response regulator
H1Q64_23855	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
H1Q64_23860	COG0828	Belongs to the bacterial ribosomal protein bS21 family
H1Q64_23865	COG1278	Cold shock
H1Q64_23875	COG0745	RESPONSE REGULATOR receiver
H1Q64_23875	COG4566	intracellular signal transduction
H1Q64_23890	COG0411	ABC transporter
H1Q64_23905	COG0683	leucine binding
H1Q64_23910	COG2814	Major facilitator Superfamily
H1Q64_23920	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H1Q64_23925	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H1Q64_23950	COG4251	negative regulation of phosphorylation
H1Q64_23955	COG0745	RESPONSE REGULATOR receiver
H1Q64_23960	COG0745	RESPONSE REGULATOR receiver
H1Q64_23965	COG4977	sequence-specific DNA binding
H1Q64_23990	COG0523	cobalamin synthesis protein
H1Q64_23995	COG2186	Transcriptional regulator
H1Q64_24000	COG1024	Enoyl-CoA hydratase
H1Q64_24005	COG1012	belongs to the aldehyde dehydrogenase family
H1Q64_24025	COG0318	PFAM AMP-dependent synthetase and ligase
H1Q64_24045	COG1959	2 iron, 2 sulfur cluster binding
H1Q64_24060	COG0583	DNA-binding transcription factor activity
H1Q64_24080	COG1959	2 iron, 2 sulfur cluster binding
H1Q64_24085	COG0583	DNA-binding transcription factor activity
H1Q64_24090	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q64_24095	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q64_24140	COG1959	2 iron, 2 sulfur cluster binding
H1Q64_24150	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H1Q64_24180	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H1Q64_24210	COG4372	Transposase
H1Q64_24215	COG3436	PFAM IS66 Orf2 family protein
H1Q64_24235	COG1136	(ABC) transporter
H1Q64_24235	COG0577	efflux transmembrane transporter activity
H1Q64_24240	COG0577	efflux transmembrane transporter activity
H1Q64_24240	COG1136	(ABC) transporter
H1Q64_24255	COG1376	ErfK ybiS ycfS ynhG family protein
H1Q64_24285	COG3920	Histidine kinase
H1Q64_24320	COG0318	PFAM AMP-dependent synthetase and ligase
H1Q64_24325	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H1Q64_24345	COG0071	Belongs to the small heat shock protein (HSP20) family
H1Q64_24355	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1Q64_24360	COG0574	Belongs to the PEP-utilizing enzyme family
H1Q64_24360	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H1Q64_24375	COG1346	cytolysis
H1Q64_24385	COG0156	8-amino-7-oxononanoate synthase activity
H1Q64_24400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1Q64_24405	COG0800	Aldolase
H1Q64_24420	COG0626	cystathionine gamma-synthase activity
H1Q64_24455	COG3547	Transposase (IS116 IS110 IS902 family)
H1Q64_24480	COG0784	Response regulator, receiver
H1Q64_24480	COG2198	Histidine kinase
H1Q64_24480	COG5002	protein histidine kinase activity
H1Q64_24530	COG3550	peptidyl-serine autophosphorylation
H1Q64_24550	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H1Q64_24560	COG4977	sequence-specific DNA binding
H1Q64_24590	COG0154	amidase activity
H1Q64_24595	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H1Q64_24600	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q64_24605	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
H1Q64_24620	COG4214	carbohydrate transport
H1Q64_24630	COG1129	ABC transporter
H1Q64_24635	COG0583	DNA-binding transcription factor activity
H1Q64_24660	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
H1Q64_24665	COG2204	response regulator
H1Q64_24735	COG3415	Transposase
H1Q64_24745	COG0477	Major facilitator Superfamily
H1Q64_24750	COG0625	glutathione transferase activity
H1Q64_24790	COG2610	gluconate transmembrane transporter activity
H1Q64_24820	COG1335	isochorismatase
H1Q64_24825	COG0277	FAD linked oxidase domain protein
H1Q64_24835	COG3842	ATPase activity
H1Q64_24840	COG1176	ABC-type spermidine putrescine transport system, permease component I
H1Q64_24845	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H1Q64_24860	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H1Q64_24865	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
H1Q64_24885	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H1Q64_24890	COG4948	Mandelate Racemase Muconate Lactonizing
H1Q64_24895	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
H1Q64_24900	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
H1Q64_24905	COG1802	Transcriptional regulator
H1Q64_24910	COG1595	DNA-templated transcription, initiation
H1Q64_24920	COG4774	siderophore transport
H1Q64_24935	COG4221	oxidoreductase activity
H1Q64_24995	COG0183	Belongs to the thiolase family
H1Q64_25025	COG0683	leucine binding
H1Q64_25030	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H1Q64_25035	COG0022	dehydrogenase e1 component
H1Q64_25035	COG0508	dehydrogenase complex catalyzes the overall conversion of
H1Q64_25040	COG1024	Enoyl-CoA hydratase
H1Q64_25045	COG0508	dehydrogenase complex catalyzes the overall conversion of
H1Q64_25070	COG0583	DNA-binding transcription factor activity
H1Q64_25075	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q64_25080	COG3959	Transketolase, thiamine diphosphate binding domain
H1Q64_25085	COG3958	Transketolase
H1Q64_25090	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H1Q64_25100	COG2084	Dehydrogenase
H1Q64_25110	COG0765	amino acid transport
H1Q64_25115	COG4597	amino acid ABC transporter
H1Q64_25130	COG0251	oxidation-reduction process
H1Q64_25135	COG3608	succinylglutamate desuccinylase aspartoacylase
H1Q64_25140	COG1609	Transcriptional regulator
H1Q64_25145	COG2188	Transcriptional regulator
H1Q64_25150	COG0179	Fumarylacetoacetate (FAA) hydrolase
H1Q64_25165	COG2301	Belongs to the HpcH HpaI aldolase family
H1Q64_25175	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H1Q64_25210	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H1Q64_25215	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H1Q64_25250	COG1032	radical SAM domain protein
H1Q64_25280	COG3609	addiction module antidote protein, CC2985 family
H1Q64_25285	COG0784	Response regulator, receiver
H1Q64_25285	COG2205	protein histidine kinase activity
H1Q64_25305	COG1063	alcohol dehydrogenase
H1Q64_25310	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H1Q64_25320	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
H1Q64_25325	COG2721	sulfolactate sulfo-lyase activity
H1Q64_25330	COG0246	Mannitol dehydrogenase
H1Q64_25350	COG3321	synthase
H1Q64_25350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1Q64_25370	COG2382	esterase
H1Q64_25375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1Q64_25390	COG3433	isochorismatase activity
H1Q64_25390	COG1535	isochorismatase
H1Q64_25400	COG1169	isochorismate synthase
H1Q64_25405	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1Q64_25415	COG0477	Major facilitator Superfamily
H1Q64_25420	COG4771	TonB-dependent receptor
H1Q64_25440	COG2201	protein-glutamate methylesterase activity
H1Q64_25445	COG2205	protein histidine kinase activity
H1Q64_25445	COG0784	Response regulator, receiver
H1Q64_25445	COG5002	protein histidine kinase activity
H1Q64_25450	COG0747	negative chemotaxis
H1Q64_25455	COG1192	Involved in chromosome partitioning
H1Q64_25470	COG4626	Terminase
H1Q64_25470	COG1802	Transcriptional regulator
H1Q64_25485	COG3721	Heme iron utilization protein
H1Q64_25495	COG0745	RESPONSE REGULATOR receiver
H1Q64_25500	COG1120	ATPase activity
H1Q64_25505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1Q64_25515	COG3720	iron ion transport
H1Q64_25525	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1Q64_25555	COG3256	nitric oxide reductase
H1Q64_25560	COG0714	Associated with various cellular activities
H1Q64_25580	COG4263	nitrous-oxide reductase activity
H1Q64_25595	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
H1Q64_25610	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H1Q64_25635	COG0826	peptidase U32
H1Q64_25650	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1Q64_25675	COG4772	TonB-dependent receptor
H1Q64_25710	COG0583	DNA-binding transcription factor activity
H1Q64_25715	COG2271	Major facilitator Superfamily
H1Q64_25740	COG0583	DNA-binding transcription factor activity
H1Q64_25760	COG0633	Ferredoxin
H1Q64_25780	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
H1Q64_25785	COG1301	dicarboxylic acid transport
H1Q64_25790	COG2828	Protein conserved in bacteria
H1Q64_25795	COG0583	DNA-binding transcription factor activity
H1Q64_25800	COG0697	spore germination
H1Q64_25815	COG2188	Transcriptional regulator
H1Q64_25845	COG1121	(ABC) transporter
H1Q64_25900	COG1175	transmembrane transport
H1Q64_25910	COG3842	ATPase activity
H1Q64_25915	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
H1Q64_25920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1Q64_25930	COG2175	clavaminate synthase activity
H1Q64_25935	COG3119	arylsulfatase activity
H1Q64_25940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1Q64_25945	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
H1Q64_25955	COG2175	clavaminate synthase activity
H1Q64_25965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1Q64_25970	COG1116	anion transmembrane transporter activity
H1Q64_25975	COG2175	clavaminate synthase activity
H1Q64_25990	COG0765	amino acid transport
H1Q64_25995	COG4597	amino acid ABC transporter
H1Q64_26000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1Q64_26015	COG1053	succinate dehydrogenase
H1Q64_26035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1Q64_26040	COG1574	metal-dependent hydrolase with the TIM-barrel fold
H1Q64_26055	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H1Q64_26060	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1Q64_26065	COG1396	sequence-specific DNA binding
H1Q64_26070	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H1Q64_26075	COG0022	dehydrogenase e1 component
H1Q64_26080	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H1Q64_26090	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
H1Q64_26090	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
H1Q64_26110	COG0628	permease
H1Q64_26140	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
H1Q64_26160	COG0542	response to heat
H1Q64_26175	COG0071	Belongs to the small heat shock protein (HSP20) family
H1Q64_26195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1Q64_26210	COG0589	response to stress
H1Q64_26215	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H1Q64_26215	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H1Q64_26250	COG0484	heat shock protein binding
H1Q64_26265	COG3293	Transposase
H1Q64_26270	COG3118	belongs to the thioredoxin family
H1Q64_26275	COG3548	integral membrane protein
H1Q64_26280	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1Q64_26285	COG4566	intracellular signal transduction
H1Q64_26335	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H1Q64_26355	COG5000	phosphorelay sensor kinase activity
H1Q64_26360	COG2204	response regulator
H1Q64_26375	COG3772	lysozyme
H1Q64_26415	COG4584	PFAM Integrase catalytic
H1Q64_26420	COG1484	DNA-dependent DNA replication
H1Q64_26460	COG0513	Belongs to the DEAD box helicase family
H1Q64_26470	COG1278	Cold shock
H1Q64_26510	COG0583	DNA-binding transcription factor activity
H1Q64_26515	COG1802	Transcriptional regulator
H1Q64_26520	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H1Q64_26530	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
H1Q64_26530	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
H1Q64_26535	COG2354	Protein conserved in bacteria
H1Q64_26555	COG1418	mRNA catabolic process
H1Q64_26560	COG1131	(ABC) transporter
H1Q64_26565	COG0842	Transport permease protein
H1Q64_26570	COG3791	Glutathione-dependent formaldehyde-activating
H1Q64_26575	COG0154	amidase activity
H1Q64_26580	COG0154	amidase activity
H1Q64_26585	COG1335	isochorismatase
H1Q64_26590	COG0747	negative chemotaxis
H1Q64_26595	COG0601	transmembrane transport
H1Q64_26600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H1Q64_26610	COG4608	Belongs to the ABC transporter superfamily
H1Q64_26615	COG1335	isochorismatase
H1Q64_26620	COG3180	Ammonia monooxygenase
H1Q64_26625	COG1802	Transcriptional regulator
H1Q64_26635	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
H1Q64_26640	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
H1Q64_26645	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
H1Q64_26650	COG2205	protein histidine kinase activity
H1Q64_26660	COG0861	Integral membrane protein TerC family
H1Q64_26670	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1Q64_26675	COG2353	YceI-like domain
H1Q64_26690	COG4566	intracellular signal transduction
H1Q64_26695	COG4566	intracellular signal transduction
H1Q64_26700	COG4191	Histidine kinase
H1Q64_26720	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1Q64_26725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1Q64_26735	COG0427	acetyl-CoA hydrolase
H1Q64_26750	COG0318	PFAM AMP-dependent synthetase and ligase
H1Q64_26755	COG1176	ABC-type spermidine putrescine transport system, permease component I
H1Q64_26760	COG3842	ATPase activity
H1Q64_26770	COG1024	Enoyl-CoA hydratase
H1Q64_26775	COG1414	Transcriptional regulator
H1Q64_26820	COG2204	response regulator
H1Q64_26830	COG2985	domain, Protein
H1Q64_26845	COG3842	ATPase activity
H1Q64_26855	COG0588	phosphoglycerate mutase activity
H1Q64_26860	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H1Q64_26870	COG0251	oxidation-reduction process
H1Q64_26880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H1Q64_26890	COG0747	negative chemotaxis
H1Q64_26900	COG0583	DNA-binding transcription factor activity
H1Q64_26910	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1Q64_26915	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H1Q64_26915	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1Q64_26920	COG1660	Displays ATPase and GTPase activities
H1Q64_26935	COG0642	Histidine kinase
H1Q64_26940	COG0745	RESPONSE REGULATOR receiver
H1Q64_26950	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
H1Q64_26970	COG0739	heme binding
H1Q64_27025	COG3415	Transposase
H1Q64_27045	COG1201	RNA secondary structure unwinding
H1Q64_27125	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
H1Q64_27135	COG0189	ligase activity
H1Q64_27150	COG0702	epimerase
H1Q64_27160	COG2154	pterin-4-alpha-carbinolamine dehydratase
H1Q64_27170	COG1229	Formylmethanofuran dehydrogenase subunit A
H1Q64_27175	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
H1Q64_27255	COG2010	Cytochrome c
H1Q64_27275	COG1573	uracil-dna glycosylase
H1Q64_27300	COG0583	DNA-binding transcription factor activity
H1Q64_27325	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q64_27340	COG3842	ATPase activity
H1Q64_27350	COG0457	Tetratricopeptide repeat
H1Q64_27370	COG1764	response to oxidative stress
H1Q64_27380	COG1960	acyl-CoA dehydrogenase activity
H1Q64_27385	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
H1Q64_27455	COG0668	transmembrane transport
H1Q64_27475	COG5001	Diguanylate cyclase
H1Q64_27495	COG1139	Iron-sulfur cluster binding protein
H1Q64_27500	COG0247	lactate metabolic process
H1Q64_27510	COG1620	l-lactate permease
H1Q64_27515	COG2186	Transcriptional regulator
H1Q64_27540	COG0243	molybdopterin cofactor binding
H1Q64_27570	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
H1Q64_27610	COG1653	transport
H1Q64_27625	COG3842	ATPase activity
H1Q64_27645	COG0840	transmembrane signaling receptor activity
H1Q64_27645	COG0840	transmembrane signaling receptor activity
H1Q64_27685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H1Q64_27690	COG1473	amidohydrolase
H1Q64_27705	COG4122	O-methyltransferase activity
H1Q64_27735	COG1971	Probably functions as a manganese efflux pump
H1Q64_27740	COG0840	transmembrane signaling receptor activity
H1Q64_27740	COG3290	protein histidine kinase activity
H1Q64_27765	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q64_27770	COG0366	Alpha amylase catalytic
H1Q64_27775	COG2388	GCN5-related N-acetyl-transferase
H1Q64_27790	COG0784	Response regulator, receiver
H1Q64_27790	COG4191	Histidine kinase
H1Q64_27795	COG0784	Response regulator, receiver
H1Q64_27795	COG5002	protein histidine kinase activity
H1Q64_27855	COG4615	Cyclic peptide transporter
H1Q64_27875	COG0586	Pfam SNARE associated Golgi protein
H1Q64_27900	COG0395	ABC-type sugar transport system, permease component
H1Q64_27915	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H1Q64_27920	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q64_27945	COG2095	MarC family integral membrane protein
H1Q64_27960	COG0840	transmembrane signaling receptor activity
H1Q64_27965	COG0835	chemotaxis
H1Q64_27970	COG2201	protein-glutamate methylesterase activity
H1Q64_27980	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
H1Q64_27990	COG0643	Histidine kinase
H1Q64_27990	COG2198	Histidine kinase
H1Q64_28000	COG2197	response regulator
H1Q64_28015	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H1Q64_28045	COG1216	Glycosyl transferase, family 2
H1Q64_28045	COG1442	glycosyl transferase family 8
H1Q64_28055	COG4178	(ABC) transporter
H1Q64_28060	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H1Q64_28065	COG3119	arylsulfatase activity
H1Q64_28080	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H1Q64_28085	COG2723	6-phospho-beta-galactosidase activity
H1Q64_28090	COG2723	6-phospho-beta-galactosidase activity
H1Q64_28140	COG4770	biotin carboxylase activity
H1Q64_28145	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
H1Q64_28150	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H1Q64_28155	COG1960	acyl-CoA dehydrogenase activity
H1Q64_28160	COG0183	Belongs to the thiolase family
H1Q64_28165	COG1960	acyl-CoA dehydrogenase activity
H1Q64_28175	COG0318	PFAM AMP-dependent synthetase and ligase
H1Q64_28210	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H1Q64_28220	COG1960	acyl-CoA dehydrogenase activity
H1Q64_28225	COG2186	Transcriptional regulator
H1Q64_28230	COG0318	PFAM AMP-dependent synthetase and ligase
H1Q64_28235	COG1309	transcriptional regulator
H1Q64_28245	COG1846	Transcriptional regulator
H1Q64_28250	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H1Q64_28260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1Q64_28280	COG2226	methyltransferase
H1Q64_28340	COG0861	Integral membrane protein TerC family
H1Q64_28350	COG0517	IMP dehydrogenase activity
H1Q64_28350	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
H1Q64_28350	COG0617	tRNA 3'-terminal CCA addition
H1Q64_28355	COG1802	Transcriptional regulator
H1Q64_28395	COG0367	asparagine synthase
H1Q64_28400	COG2918	glutathione biosynthetic process
H1Q64_28400	COG1181	Belongs to the D-alanine--D-alanine ligase family
H1Q64_28400	COG0189	ligase activity
H1Q64_28405	COG1363	Peptidase, m42
H1Q64_28415	COG1966	Carbon starvation protein
H1Q64_28425	COG3275	phosphorelay sensor kinase activity
H1Q64_28465	COG0848	biopolymer transport protein
H1Q64_28475	COG4566	intracellular signal transduction
H1Q64_28480	COG4191	Histidine kinase
H1Q64_28485	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H1Q64_28530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1Q64_28565	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q64_28590	COG0800	Aldolase
H1Q64_28595	COG3734	2-keto-3-deoxy-galactonokinase
H1Q64_28600	COG1414	Transcriptional regulator
H1Q64_28605	COG0542	response to heat
H1Q64_28625	COG0402	S-adenosylhomocysteine deaminase activity
H1Q64_28630	COG1116	anion transmembrane transporter activity
H1Q64_28635	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1Q64_28660	COG3842	ATPase activity
H1Q64_28680	COG2351	hydroxyisourate hydrolase activity
H1Q64_28710	COG2226	methyltransferase
H1Q64_28735	COG3387	PFAM Glycoside hydrolase 15-related
H1Q64_28745	COG2197	response regulator
H1Q64_28750	COG2197	response regulator
H1Q64_28765	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
H1Q64_28770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H1Q64_28775	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H1Q64_28780	COG0438	transferase activity, transferring glycosyl groups
H1Q64_28800	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H1Q64_28820	COG0438	transferase activity, transferring glycosyl groups
H1Q64_28850	COG0583	DNA-binding transcription factor activity
H1Q64_28855	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H1Q64_28870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H1Q64_28875	COG4172	Belongs to the ABC transporter superfamily
H1Q64_28895	COG0028	Belongs to the TPP enzyme family
H1Q64_28900	COG3246	L-lysine catabolic process to acetate
H1Q64_28915	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H1Q64_28920	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
H1Q64_28930	COG1850	ribulose-bisphosphate carboxylase activity
H1Q64_28940	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1Q64_28970	COG0670	Belongs to the BI1 family
H1Q64_28985	COG4459	periplasmic nitrate reductase
H1Q64_29010	COG3005	denitrification pathway
H1Q64_29025	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
H1Q64_29040	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H1Q64_29045	COG1845	cytochrome c oxidase, subunit III
H1Q64_29055	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H1Q64_29060	COG0477	Major facilitator Superfamily
H1Q64_29070	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H1Q64_29085	COG5001	Diguanylate cyclase
H1Q64_29100	COG0392	lysyltransferase activity
H1Q64_29105	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H1Q64_29155	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H1Q64_29175	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
H1Q64_29180	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H1Q64_29200	COG1846	Transcriptional regulator
H1Q64_29205	COG1764	response to oxidative stress
H1Q64_29230	COG2113	Glycine betaine
H1Q64_29235	COG4176	ABC-type proline glycine betaine transport system permease component
H1Q64_29240	COG4175	Glycine betaine
H1Q64_29275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1Q64_29280	COG0765	amino acid transport
H1Q64_29330	COG0840	transmembrane signaling receptor activity
H1Q64_29335	COG4178	(ABC) transporter
H1Q64_29345	COG1475	DNA binding
H1Q64_29350	COG1192	Involved in chromosome partitioning
H1Q64_29355	COG4783	chaperone-mediated protein folding
H1Q64_29375	COG3622	Belongs to the hyi family
H1Q64_29385	COG1215	transferase activity, transferring glycosyl groups
H1Q64_29400	COG3307	-O-antigen
H1Q64_29405	COG3206	protein involved in exopolysaccharide biosynthesis
H1Q64_29405	COG0489	protein tyrosine kinase activity
H1Q64_29435	COG1216	Glycosyl transferase, family 2
H1Q64_29510	COG0640	Transcriptional regulator
H1Q64_29515	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H1Q64_29535	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1Q64_29545	COG4566	intracellular signal transduction
H1Q64_29560	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q64_29570	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H1Q64_29580	COG1994	Peptidase M50
H1Q64_29580	COG0517	IMP dehydrogenase activity
H1Q64_29595	COG1522	sequence-specific DNA binding
H1Q64_29610	COG1744	ABC transporter substrate-binding protein PnrA-like
H1Q64_29620	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q64_29630	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H1Q64_29635	COG4608	Belongs to the ABC transporter superfamily
H1Q64_29650	COG0601	transmembrane transport
H1Q64_29655	COG0747	negative chemotaxis
H1Q64_29685	COG2239	Acts as a magnesium transporter
H1Q64_29690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H1Q64_29690	COG2022	thiamine diphosphate biosynthetic process
H1Q64_29700	COG2022	thiamine diphosphate biosynthetic process
H1Q64_29755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1Q64_29760	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
H1Q64_29765	COG3386	PFAM SMP-30 Gluconolaconase
H1Q64_29770	COG0191	fructose-bisphosphate aldolase activity
H1Q64_29785	COG0348	domain, Protein
H1Q64_29795	COG4251	negative regulation of phosphorylation
H1Q64_29800	COG0784	Response regulator, receiver
H1Q64_29845	COG1595	DNA-templated transcription, initiation
H1Q64_29855	COG1045	serine acetyltransferase
H1Q64_29870	COG3842	ATPase activity
H1Q64_29875	COG1176	ABC-type spermidine putrescine transport system, permease component I
H1Q64_29880	COG1178	ABC-type Fe3 transport system permease component
H1Q64_29890	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H1Q64_29895	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H1Q64_29900	COG2233	PERMEase
H1Q64_29905	COG1254	Belongs to the acylphosphatase family
H1Q64_29925	COG2010	Cytochrome c
H1Q64_29925	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H1Q64_29950	COG1131	(ABC) transporter
H1Q64_29975	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H1Q64_29975	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H1Q64_29985	COG2201	protein-glutamate methylesterase activity
H1Q64_29990	COG2201	protein-glutamate methylesterase activity
H1Q64_29995	COG2205	protein histidine kinase activity
H1Q64_29995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1Q64_30015	COG0012	GTP binding
H1Q64_30020	COG5001	Diguanylate cyclase
H1Q64_30020	COG3300	MHYT domain
H1Q64_30030	COG0583	DNA-binding transcription factor activity
H1Q64_30035	COG2814	Major facilitator Superfamily
H1Q64_30060	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q64_30065	COG0183	Belongs to the thiolase family
H1Q64_30125	COG0745	RESPONSE REGULATOR receiver
H1Q64_30130	COG5002	protein histidine kinase activity
H1Q64_30150	COG4584	PFAM Integrase catalytic
H1Q64_30195	COG1312	Catalyzes the dehydration of D-mannonate
H1Q64_30200	COG0246	Mannitol dehydrogenase
H1Q64_30215	COG1802	Transcriptional regulator
H1Q64_30220	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q64_30225	COG1917	Cupin 2, conserved barrel domain protein
H1Q64_30230	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H1Q64_30240	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
H1Q64_30245	COG0667	Aldo Keto reductase
H1Q64_30250	COG1802	Transcriptional regulator
H1Q64_30260	COG1904	glucuronate isomerase
H1Q64_30265	COG2721	sulfolactate sulfo-lyase activity
H1Q64_30300	COG0861	Integral membrane protein TerC family
H1Q64_30345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H1Q64_30350	COG2188	Transcriptional regulator
H1Q64_30365	COG0154	amidase activity
H1Q64_30380	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H1Q64_30385	COG1960	acyl-CoA dehydrogenase activity
H1Q64_30390	COG2079	MmgE PrpD family protein
H1Q64_30410	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H1Q64_30415	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q64_30430	COG1595	DNA-templated transcription, initiation
H1Q64_30460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1Q64_30500	COG1132	(ABC) transporter
H1Q64_30515	COG2199	diguanylate cyclase activity
H1Q64_30515	COG2203	Gaf domain
H1Q64_30535	COG0405	Gamma-glutamyltransferase
H1Q64_30565	COG1858	cytochrome C peroxidase
H1Q64_30590	COG4964	Belongs to the GSP D family
H1Q64_30715	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
H1Q64_30740	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
H1Q64_30750	COG3845	ABC transporter
H1Q64_30755	COG4603	Belongs to the binding-protein-dependent transport system permease family
H1Q64_30760	COG1079	Belongs to the binding-protein-dependent transport system permease family
H1Q64_30765	COG0402	S-adenosylhomocysteine deaminase activity
H1Q64_30770	COG0840	transmembrane signaling receptor activity
H1Q64_30775	COG4191	Histidine kinase
H1Q64_30795	COG1414	Transcriptional regulator
H1Q64_30800	COG3383	formate dehydrogenase (NAD+) activity
H1Q64_30820	COG1597	lipid kinase activity
H1Q64_30830	COG0628	permease
H1Q64_30835	COG3416	Protein conserved in bacteria
H1Q64_30895	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H1Q64_30905	COG1338	Plays a role in the flagellum-specific transport system
H1Q64_30910	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H1Q64_30920	COG1766	The M ring may be actively involved in energy transduction
H1Q64_30985	COG3005	denitrification pathway
H1Q64_30995	COG0243	molybdopterin cofactor binding
H1Q64_31015	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
H1Q64_31020	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
H1Q64_31025	COG4786	Flagellar basal body rod
H1Q64_31030	COG4786	Flagellar basal body rod
H1Q64_31040	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
H1Q64_31045	COG1360	Flagellar Motor Protein
H1Q64_31125	COG1454	alcohol dehydrogenase
H1Q64_31125	COG1012	belongs to the aldehyde dehydrogenase family
H1Q64_31140	COG0583	DNA-binding transcription factor activity
H1Q64_31145	COG0028	Belongs to the TPP enzyme family
H1Q64_31150	COG1012	belongs to the aldehyde dehydrogenase family
H1Q64_31175	COG0784	Response regulator, receiver
H1Q64_31175	COG4191	Histidine kinase
H1Q64_31180	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
H1Q64_31205	COG0583	DNA-binding transcription factor activity
H1Q64_31210	COG2855	membrane
H1Q64_31225	COG0546	phosphoglycolate phosphatase activity
H1Q64_31245	COG1192	Involved in chromosome partitioning
H1Q64_31250	COG1475	DNA binding
H1Q64_31255	COG0028	Belongs to the TPP enzyme family
H1Q64_31270	COG0437	4 iron, 4 sulfur cluster binding
H1Q64_31275	COG0243	molybdopterin cofactor binding
H1Q64_31280	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H1Q64_31285	COG0045	succinate-CoA ligase (ADP-forming) activity
H1Q64_31290	COG1012	belongs to the aldehyde dehydrogenase family
H1Q64_31310	COG0280	phosphate acetyltransferase
H1Q64_31315	COG1414	Transcriptional regulator
H1Q64_31320	COG1414	Transcriptional regulator
H1Q64_31325	COG1522	sequence-specific DNA binding
H1Q64_31330	COG0251	oxidation-reduction process
H1Q64_31335	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H1Q64_31375	COG1473	amidohydrolase
H1Q64_31380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H1Q64_31410	COG2197	response regulator
H1Q64_31415	COG3920	Histidine kinase
H1Q64_31425	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1Q64_31425	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1Q64_31430	COG1105	Belongs to the carbohydrate kinase PfkB family
H1Q64_31435	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1Q64_31435	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H1Q64_31440	COG1609	Transcriptional regulator
H1Q64_31450	COG1335	isochorismatase
H1Q64_31455	COG2309	aminopeptidase activity
H1Q64_31460	COG0596	Alpha beta hydrolase
H1Q64_31465	COG3473	Maleate cis-trans isomerase
H1Q64_31495	COG0683	leucine binding
H1Q64_31510	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
H1Q64_31570	COG0154	amidase activity
H1Q64_31595	COG2086	electron transfer activity
H1Q64_31600	COG0277	FAD linked oxidase domain protein
H1Q64_31610	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H1Q64_31625	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
H1Q64_31630	COG0567	Dehydrogenase, E1 component
H1Q64_31650	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H1Q64_31660	COG1845	cytochrome c oxidase, subunit III
H1Q64_31670	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
H1Q64_31680	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H1Q64_31685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1Q64_31690	COG1120	ATPase activity
H1Q64_31695	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
H1Q64_31700	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
H1Q64_31715	COG1802	Transcriptional regulator
H1Q64_31720	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H1Q64_31740	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H1Q64_31750	COG5443	negative regulation of bacterial-type flagellum assembly
H1Q64_31770	COG2814	Major facilitator Superfamily
H1Q64_31790	COG1815	bacterial-type flagellum-dependent cell motility
H1Q64_31795	COG1558	bacterial-type flagellum-dependent cell motility
H1Q64_31800	COG1677	Flagellar hook-basal body complex protein FliE
H1Q64_31805	COG4794	Type iii secretion
H1Q64_31815	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H1Q64_31820	COG1684	flagellar biosynthetic protein fliR
H1Q64_31825	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H1Q64_31835	COG1522	sequence-specific DNA binding
H1Q64_31845	COG0028	Belongs to the TPP enzyme family
H1Q64_31855	COG4191	Histidine kinase
H1Q64_31865	COG5487	UPF0391 membrane protein
H1Q64_31870	COG0793	Belongs to the peptidase S41A family
H1Q64_31875	COG0583	DNA-binding transcription factor activity
H1Q64_31880	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q64_31905	COG5001	Diguanylate cyclase
H1Q64_31905	COG3300	MHYT domain
H1Q64_31930	COG1706	bacterial-type flagellum-dependent cell motility
H1Q64_31945	COG1749	Flagellar hook protein flgE
H1Q64_31975	COG0861	Integral membrane protein TerC family
H1Q64_31980	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
H1Q64_31990	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H1Q64_31995	COG1802	Transcriptional regulator
H1Q64_32000	COG0697	spore germination
H1Q64_32005	COG2116	formate transmembrane transporter activity
H1Q64_32010	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H1Q64_32015	COG0469	pyruvate kinase activity
H1Q64_32020	COG4251	negative regulation of phosphorylation
H1Q64_32030	COG1309	transcriptional regulator
H1Q64_32035	COG1309	transcriptional regulator
H1Q64_32040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1Q64_32045	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1Q64_32050	COG0837	glucose binding
H1Q64_32050	COG1737	Transcriptional regulator
H1Q64_32055	COG1882	Formate acetyltransferase
H1Q64_32060	COG0148	phosphopyruvate hydratase activity
H1Q64_32070	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H1Q64_32080	COG1028	Short-chain dehydrogenase reductase Sdr
H1Q64_32085	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
H1Q64_32090	COG1802	Transcriptional regulator
H1Q64_32110	COG0668	transmembrane transport
H1Q64_32130	COG1012	belongs to the aldehyde dehydrogenase family
H1Q64_32185	COG2133	pyrroloquinoline quinone binding
H1Q64_32200	COG0583	DNA-binding transcription factor activity
H1Q64_32210	COG1733	regulation of RNA biosynthetic process
H1Q64_32215	COG0702	epimerase
H1Q64_32220	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1Q64_32225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1Q64_32230	COG1309	transcriptional regulator
H1Q64_32240	COG2132	Multicopper oxidase
H1Q64_32245	COG5039	Polysaccharide pyruvyl transferase
H1Q64_32260	COG0725	ABC transporter, periplasmic molybdate-binding protein
H1Q64_32265	COG0246	Mannitol dehydrogenase
H1Q64_32285	COG0129	dihydroxy-acid dehydratase activity
H1Q64_32295	COG4214	carbohydrate transport
H1Q64_32330	COG1879	ABC-type sugar transport system periplasmic component
H1Q64_32335	COG1129	ABC transporter
H1Q64_32340	COG1172	Belongs to the binding-protein-dependent transport system permease family
H1Q64_32345	COG1172	Belongs to the binding-protein-dependent transport system permease family
H1Q64_32355	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
H1Q64_32360	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H1Q64_32370	COG1496	oxidoreductase activity
H1Q64_32390	COG0318	PFAM AMP-dependent synthetase and ligase
H1Q64_32395	COG1278	Cold shock
H1Q64_32400	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
H1Q64_32405	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H1Q64_32410	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H1Q64_32410	COG0574	Belongs to the PEP-utilizing enzyme family
H1Q64_32420	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
H1Q64_32425	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H1Q64_32430	COG4106	trans-aconitate 2-methyltransferase activity
H1Q64_32430	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
H1Q64_32440	COG0156	8-amino-7-oxononanoate synthase activity
H1Q64_32455	COG0564	pseudouridine synthase activity
H1Q64_32465	COG0484	heat shock protein binding
H1Q64_32490	COG0463	Glycosyl transferase, family 2
H1Q64_32505	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H1Q64_32530	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
H1Q64_32565	COG2192	nodulation
H1Q64_32590	COG1088	dTDP-glucose 4,6-dehydratase activity
H1Q64_32615	COG0528	UMP kinase activity
H1Q64_32620	COG0528	UMP kinase activity
H1Q64_32640	COG1051	belongs to the nudix hydrolase family
H1Q64_32655	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H1Q64_32665	COG1086	Polysaccharide biosynthesis protein
H1Q64_32670	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H1Q64_32680	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
H1Q64_32690	COG1475	DNA binding
H1Q64_32695	COG1192	Involved in chromosome partitioning
H1Q64_32710	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H1Q64_32745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H1Q64_32775	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H1Q64_32785	COG1215	transferase activity, transferring glycosyl groups
H1Q64_32820	COG0438	transferase activity, transferring glycosyl groups
H1Q64_32820	COG1216	Glycosyl transferase, family 2
H1Q64_32845	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H1Q64_32860	COG1216	Glycosyl transferase, family 2
H1Q64_32860	COG0438	transferase activity, transferring glycosyl groups
H1Q64_32870	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
H1Q64_32890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H1Q64_32925	COG1091	dTDP-4-dehydrorhamnose reductase activity
H1Q64_32930	COG1088	dTDP-glucose 4,6-dehydratase activity
H1Q64_32935	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
H1Q64_32940	COG0297	glycogen (starch) synthase activity
H1Q64_32950	COG0579	oxidoreductase
H1Q64_32955	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H1Q64_32975	COG4106	trans-aconitate 2-methyltransferase activity
H1Q64_32990	COG2076	Multidrug Resistance protein
H1Q64_33000	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
H1Q64_33005	COG0500	methyltransferase
H1Q64_33040	COG2226	methyltransferase
H1Q64_33065	COG0438	transferase activity, transferring glycosyl groups
H1Q64_33080	COG1216	Glycosyl transferase, family 2
H1Q64_33110	COG0714	Associated with various cellular activities
H1Q64_33140	COG2205	protein histidine kinase activity
H1Q64_33145	COG0784	Response regulator, receiver
H1Q64_33145	COG2205	protein histidine kinase activity
H1Q64_33180	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H1Q64_33200	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H1Q64_33225	COG2205	protein histidine kinase activity
H1Q64_33255	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H1Q64_33280	COG1278	Cold shock
H1Q64_33285	COG2204	response regulator
H1Q64_33290	COG0784	Response regulator, receiver
H1Q64_33290	COG4191	Histidine kinase
H1Q64_33350	COG4651	solute:proton antiporter activity
H1Q64_33350	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H1Q64_33365	COG3243	poly(R)-hydroxyalkanoic acid synthase
H1Q64_33375	COG3932	Exopolysaccharide synthesis, ExoD
H1Q64_33430	COG0471	metal ion transport
H1Q64_33430	COG3273	potassium ion transport
H1Q64_33435	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H1Q64_33460	COG4584	PFAM Integrase catalytic
H1Q64_33465	COG4584	PFAM Integrase catalytic
H1Q64_33470	COG1484	DNA-dependent DNA replication
H1Q64_33485	COG5002	protein histidine kinase activity
H1Q64_33490	COG0745	RESPONSE REGULATOR receiver