locus-tag	class	description
AMK58_00045	COG1366	Belongs to the anti-sigma-factor antagonist family
AMK58_00055	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AMK58_00095	COG0784	Response regulator, receiver
AMK58_00095	COG2205	protein histidine kinase activity
AMK58_00105	COG0180	Tryptophanyl-tRNA synthetase
AMK58_00110	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AMK58_00120	COG3012	SEC-C Motif Domain Protein
AMK58_00135	COG0110	maltose O-acetyltransferase activity
AMK58_00140	COG1309	transcriptional regulator
AMK58_00145	COG1028	Short-chain dehydrogenase reductase Sdr
AMK58_00160	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AMK58_00165	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AMK58_00170	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AMK58_00195	COG0438	transferase activity, transferring glycosyl groups
AMK58_00200	COG3706	GGDEF domain
AMK58_00215	COG1132	(ABC) transporter
AMK58_00220	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMK58_00220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AMK58_00245	COG0747	negative chemotaxis
AMK58_00250	COG0601	transmembrane transport
AMK58_00255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AMK58_00265	COG1234	tRNA 3'-trailer cleavage
AMK58_00285	COG0745	RESPONSE REGULATOR receiver
AMK58_00350	COG1475	DNA binding
AMK58_00355	COG1192	Involved in chromosome partitioning
AMK58_00360	COG0357	Ribosomal RNA small subunit methyltransferase G
AMK58_00365	COG0445	tRNA wobble uridine modification
AMK58_00375	COG3411	Ferredoxin
AMK58_00385	COG1331	Highly conserved protein containing a thioredoxin domain
AMK58_00390	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AMK58_00400	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AMK58_00405	COG0237	dephospho-CoA kinase activity
AMK58_00450	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AMK58_00455	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AMK58_00465	COG4395	Tim44
AMK58_00470	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AMK58_00525	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AMK58_00535	COG2205	protein histidine kinase activity
AMK58_00550	COG1556	Lactate utilization protein
AMK58_00555	COG1139	Iron-sulfur cluster binding protein
AMK58_00560	COG0247	lactate metabolic process
AMK58_00565	COG0840	transmembrane signaling receptor activity
AMK58_00580	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AMK58_00585	COG1121	(ABC) transporter
AMK58_00595	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AMK58_00600	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AMK58_00610	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AMK58_00625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AMK58_00630	COG0730	response to heat
AMK58_00655	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AMK58_00665	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AMK58_00700	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AMK58_00705	COG1702	phosphate starvation-inducible protein PhoH
AMK58_00715	COG1253	flavin adenine dinucleotide binding
AMK58_00720	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AMK58_00725	COG1396	sequence-specific DNA binding
AMK58_00730	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AMK58_00735	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AMK58_00740	COG2329	Antibiotic biosynthesis monooxygenase
AMK58_00745	COG0779	Required for maturation of 30S ribosomal subunits
AMK58_00770	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AMK58_00780	COG1185	polyribonucleotide nucleotidyltransferase activity
AMK58_00790	COG2321	neutral zinc metallopeptidase
AMK58_00800	COG1509	lysine 2,3-aminomutase activity
AMK58_00805	COG0584	glycerophosphoryl diester phosphodiesterase
AMK58_00820	COG1592	Rubrerythrin
AMK58_00850	COG0039	L-malate dehydrogenase activity
AMK58_00855	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AMK58_00860	COG4166	transmembrane transport
AMK58_00870	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AMK58_00875	COG2226	methyltransferase
AMK58_00880	COG0457	Tetratricopeptide repeat
AMK58_00880	COG0859	PFAM glycosyl transferase family 9
AMK58_00890	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AMK58_00900	COG1024	Enoyl-CoA hydratase
AMK58_00905	COG0268	Binds directly to 16S ribosomal RNA
AMK58_00910	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AMK58_00915	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AMK58_00920	COG3842	ATPase activity
AMK58_00940	COG1176	ABC-type spermidine putrescine transport system, permease component I
AMK58_00945	COG1177	transmembrane transport
AMK58_00960	COG2132	Multicopper oxidase
AMK58_01010	COG2217	Heavy metal translocating P-type atpase
AMK58_01015	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMK58_01020	COG0280	phosphate acetyltransferase
AMK58_01020	COG0281	malic enzyme
AMK58_01025	COG5002	protein histidine kinase activity
AMK58_01030	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AMK58_01035	COG0573	inorganic phosphate transmembrane transporter activity
AMK58_01045	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AMK58_01050	COG0704	Plays a role in the regulation of phosphate uptake
AMK58_01055	COG0745	RESPONSE REGULATOR receiver
AMK58_01070	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AMK58_01080	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AMK58_01090	COG0756	dUTP diphosphatase activity
AMK58_01095	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AMK58_01100	COG2204	response regulator
AMK58_01105	COG1278	Cold shock
AMK58_01110	COG0784	Response regulator, receiver
AMK58_01110	COG2205	protein histidine kinase activity
AMK58_01110	COG5002	protein histidine kinase activity
AMK58_01115	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AMK58_01120	COG1321	iron dependent repressor
AMK58_01120	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AMK58_01125	COG1121	(ABC) transporter
AMK58_01130	COG0803	Belongs to the bacterial solute-binding protein 9 family
AMK58_01165	COG2205	protein histidine kinase activity
AMK58_01165	COG2202	Pas domain
AMK58_01185	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AMK58_01190	COG1253	flavin adenine dinucleotide binding
AMK58_01205	COG0477	Major facilitator Superfamily
AMK58_01210	COG0583	DNA-binding transcription factor activity
AMK58_01235	COG4783	chaperone-mediated protein folding
AMK58_01240	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AMK58_01245	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AMK58_01255	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AMK58_01260	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AMK58_01265	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AMK58_01280	COG0784	Response regulator, receiver
AMK58_01280	COG3437	response regulator, receiver
AMK58_01290	COG0583	DNA-binding transcription factor activity
AMK58_01300	COG0481	GTPase activity
AMK58_01310	COG0297	glycogen (starch) synthase activity
AMK58_01315	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AMK58_01320	COG0004	ammonium transporteR
AMK58_01330	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AMK58_01345	COG3806	Anti-sigma factor
AMK58_01350	COG1595	DNA-templated transcription, initiation
AMK58_01360	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AMK58_01375	COG0137	argininosuccinate synthase activity
AMK58_01390	COG2897	thiosulfate sulfurtransferase activity
AMK58_01395	COG3339	Conserved Protein
AMK58_01400	COG0697	spore germination
AMK58_01405	COG4235	cytochrome complex assembly
AMK58_01410	COG3088	subunit of a heme lyase
AMK58_01415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AMK58_01420	COG1138	Cytochrome C-type biogenesis protein
AMK58_01425	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AMK58_01435	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AMK58_01440	COG0583	DNA-binding transcription factor activity
AMK58_01450	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AMK58_01455	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AMK58_01460	COG1573	uracil-dna glycosylase
AMK58_01480	COG0598	Magnesium transport protein CorA
AMK58_01485	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AMK58_01490	COG1872	DUF167
AMK58_01535	COG2985	domain, Protein
AMK58_01540	COG4133	protoheme IX ABC transporter activity
AMK58_01545	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AMK58_01555	COG1074	ATP-dependent DNA helicase activity
AMK58_01565	COG2887	Belongs to the helicase family. UvrD subfamily
AMK58_01570	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AMK58_01580	COG0802	atpase or kinase
AMK58_01600	COG0745	RESPONSE REGULATOR receiver
AMK58_01610	COG1252	NADH dehydrogenase
AMK58_01615	COG2205	protein histidine kinase activity
AMK58_01625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMK58_01630	COG0133	tryptophan synthase activity
AMK58_01640	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AMK58_01645	COG0285	dihydrofolate synthase activity
AMK58_01660	COG1028	Short-chain dehydrogenase reductase Sdr
AMK58_01670	COG2205	protein histidine kinase activity
AMK58_01675	COG0302	gtp cyclohydrolase
AMK58_01685	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AMK58_01695	COG0302	gtp cyclohydrolase
AMK58_01700	COG2967	ApaG domain
AMK58_01730	COG0514	ATP-dependent DNA helicase (RecQ)
AMK58_01795	COG0443	Heat shock 70 kDa protein
AMK58_01800	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AMK58_01885	COG0582	viral genome integration into host DNA
AMK58_01905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AMK58_01920	COG0784	Response regulator, receiver
AMK58_01920	COG5002	protein histidine kinase activity
AMK58_01920	COG2205	protein histidine kinase activity
AMK58_01940	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AMK58_01945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMK58_01945	COG4191	Histidine kinase
AMK58_01955	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AMK58_01965	COG2885	chlorophyll binding
AMK58_01995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMK58_02025	COG0181	hydroxymethylbilane synthase activity
AMK58_02030	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AMK58_02045	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AMK58_02050	COG2350	Protein conserved in bacteria
AMK58_02065	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AMK58_02080	COG5508	conserved small protein
AMK58_02085	COG0501	Belongs to the peptidase M48B family
AMK58_02100	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AMK58_02100	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AMK58_02110	COG0138	bifunctional purine biosynthesis protein purh
AMK58_02135	COG2264	protein methyltransferase activity
AMK58_02140	COG2902	Dehydrogenase
AMK58_02145	COG3437	response regulator, receiver
AMK58_02145	COG2770	Histidine kinase
AMK58_02155	COG0840	transmembrane signaling receptor activity
AMK58_02170	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AMK58_02185	COG3118	belongs to the thioredoxin family
AMK58_02190	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AMK58_02195	COG2835	tetraacyldisaccharide 4'-kinase activity
AMK58_02230	COG1285	pathogenesis
AMK58_02235	COG2814	Major facilitator Superfamily
AMK58_02245	COG2205	protein histidine kinase activity
AMK58_02245	COG0784	Response regulator, receiver
AMK58_02265	COG0395	ABC-type sugar transport system, permease component
AMK58_02275	COG0625	glutathione transferase activity
AMK58_02295	COG0513	Belongs to the DEAD box helicase family
AMK58_02320	COG4191	Histidine kinase
AMK58_02325	COG1366	Belongs to the anti-sigma-factor antagonist family
AMK58_02335	COG0745	RESPONSE REGULATOR receiver
AMK58_02355	COG3706	GGDEF domain
AMK58_02355	COG0745	RESPONSE REGULATOR receiver
AMK58_02360	COG3706	GGDEF domain
AMK58_02360	COG0745	RESPONSE REGULATOR receiver
AMK58_02370	COG1366	Belongs to the anti-sigma-factor antagonist family
AMK58_02375	COG0840	transmembrane signaling receptor activity
AMK58_02380	COG2201	protein-glutamate methylesterase activity
AMK58_02385	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AMK58_02395	COG0840	transmembrane signaling receptor activity
AMK58_02400	COG0835	chemotaxis
AMK58_02405	COG0643	Histidine kinase
AMK58_02405	COG2198	Histidine kinase
AMK58_02420	COG5002	protein histidine kinase activity
AMK58_02430	COG2176	DNA-directed DNA polymerase activity
AMK58_02430	COG5002	protein histidine kinase activity
AMK58_02435	COG0745	RESPONSE REGULATOR receiver
AMK58_02450	COG2917	probably involved in intracellular septation
AMK58_02460	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AMK58_02465	COG0552	protein localization to endoplasmic reticulum
AMK58_02470	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AMK58_02475	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AMK58_02525	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AMK58_02540	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AMK58_02545	COG3706	GGDEF domain
AMK58_02550	COG2205	protein histidine kinase activity
AMK58_02555	COG0508	dehydrogenase complex catalyzes the overall conversion of
AMK58_02570	COG0045	succinate-CoA ligase (ADP-forming) activity
AMK58_02575	COG0039	L-malate dehydrogenase activity
AMK58_02590	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
AMK58_02595	COG2076	Multidrug Resistance protein
AMK58_02605	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AMK58_02610	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AMK58_02610	COG1199	ATP-dependent helicase activity
AMK58_02615	COG0840	transmembrane signaling receptor activity
AMK58_02625	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AMK58_02635	COG2972	Histidine kinase
AMK58_02635	COG0840	transmembrane signaling receptor activity
AMK58_02650	COG2084	Dehydrogenase
AMK58_02660	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AMK58_02695	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AMK58_02775	COG0531	amino acid
AMK58_02795	COG3485	protocatechuate 3,4-dioxygenase
AMK58_02805	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AMK58_02815	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AMK58_02835	COG3335	DDE superfamily endonuclease
AMK58_02850	COG3328	transposase activity
AMK58_02865	COG1074	ATP-dependent DNA helicase activity
AMK58_02885	COG2814	Major facilitator Superfamily
AMK58_03010	COG0167	dihydroorotate dehydrogenase activity
AMK58_03020	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AMK58_03025	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AMK58_03030	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AMK58_03095	COG3119	arylsulfatase activity
AMK58_03130	COG0714	Associated with various cellular activities
AMK58_03140	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AMK58_03155	COG0583	DNA-binding transcription factor activity
AMK58_03160	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AMK58_03165	COG1024	Enoyl-CoA hydratase
AMK58_03175	COG0154	amidase activity
AMK58_03180	COG1028	Short-chain dehydrogenase reductase Sdr
AMK58_03190	COG0559	Belongs to the binding-protein-dependent transport system permease family
AMK58_03200	COG0411	ABC transporter
AMK58_03230	COG1136	(ABC) transporter
AMK58_03260	COG2304	oxidoreductase activity
AMK58_03265	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMK58_03310	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AMK58_03315	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AMK58_03325	COG0783	Belongs to the Dps family
AMK58_03335	COG0492	ferredoxin-NADP+ reductase activity
AMK58_03350	COG3660	Nucleoside-diphosphate-sugar epimerase
AMK58_03355	COG1522	sequence-specific DNA binding
AMK58_03365	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AMK58_03370	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AMK58_03395	COG1674	ftsk spoiiie
AMK58_03415	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AMK58_03425	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AMK58_03430	COG1028	Short-chain dehydrogenase reductase Sdr
AMK58_03435	COG1238	metal cluster binding
AMK58_03455	COG1012	belongs to the aldehyde dehydrogenase family
AMK58_03470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMK58_03470	COG2205	protein histidine kinase activity
AMK58_03480	COG1131	(ABC) transporter
AMK58_03530	COG1116	anion transmembrane transporter activity
AMK58_03570	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
AMK58_03580	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AMK58_03585	COG2205	protein histidine kinase activity
AMK58_03585	COG0784	Response regulator, receiver
AMK58_03595	COG0745	RESPONSE REGULATOR receiver
AMK58_03600	COG2766	serine protein kinase
AMK58_03605	COG2718	Belongs to the UPF0229 family
AMK58_03610	COG2719	SpoVR family
AMK58_03625	COG1643	Atp-dependent helicase
AMK58_03630	COG1116	anion transmembrane transporter activity
AMK58_03650	COG0745	RESPONSE REGULATOR receiver
AMK58_03675	COG0330	HflC and HflK could
AMK58_03680	COG0628	permease
AMK58_03690	COG3180	Ammonia monooxygenase
AMK58_03695	COG2988	succinylglutamate desuccinylase activity
AMK58_03735	COG2202	Pas domain
AMK58_03735	COG2205	protein histidine kinase activity
AMK58_03745	COG2205	protein histidine kinase activity
AMK58_03755	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AMK58_03765	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
AMK58_03795	COG2197	response regulator
AMK58_03800	COG2197	response regulator
AMK58_03805	COG0210	DNA helicase
AMK58_03820	COG2264	protein methyltransferase activity
AMK58_03830	COG0006	proline dipeptidase activity
AMK58_03830	COG0006	proline dipeptidase activity
AMK58_03835	COG0745	RESPONSE REGULATOR receiver
AMK58_03850	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AMK58_03855	COG0497	DNA recombination
AMK58_03875	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AMK58_03890	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AMK58_03895	COG0849	cell division
AMK58_03900	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AMK58_03905	COG1181	Belongs to the D-alanine--D-alanine ligase family
AMK58_03910	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AMK58_03915	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AMK58_03925	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AMK58_03940	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AMK58_03950	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AMK58_03970	COG2001	Belongs to the MraZ family
AMK58_03990	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AMK58_04005	COG0277	FAD linked oxidase domain protein
AMK58_04010	COG2084	Dehydrogenase
AMK58_04025	COG4191	Histidine kinase
AMK58_04025	COG0784	Response regulator, receiver
AMK58_04050	COG0142	geranyltranstransferase activity
AMK58_04060	COG2890	protein-(glutamine-N5) methyltransferase activity
AMK58_04080	COG0752	glycyl-tRNA synthetase alpha subunit
AMK58_04085	COG0751	glycine-tRNA ligase activity
AMK58_04090	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AMK58_04095	COG1346	cytolysis
AMK58_04100	COG1380	Effector of murein hydrolase LrgA
AMK58_04105	COG1073	alpha beta
AMK58_04130	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AMK58_04140	COG2205	protein histidine kinase activity
AMK58_04170	COG3409	Peptidoglycan-binding domain 1 protein
AMK58_04170	COG0860	N-Acetylmuramoyl-L-alanine amidase
AMK58_04175	COG3108	Peptidase M15
AMK58_04190	COG0840	transmembrane signaling receptor activity
AMK58_04220	COG0511	ligase activity, forming carbon-carbon bonds
AMK58_04225	COG0439	Biotin carboxylase
AMK58_04230	COG3719	Belongs to the RNase T2 family
AMK58_04255	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AMK58_04280	COG1686	Belongs to the peptidase S11 family
AMK58_04295	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AMK58_04300	COG0746	molybdenum cofactor guanylyltransferase activity
AMK58_04325	COG0243	molybdopterin cofactor binding
AMK58_04325	COG3383	formate dehydrogenase (NAD+) activity
AMK58_04330	COG0437	4 iron, 4 sulfur cluster binding
AMK58_04355	COG0235	Class ii aldolase
AMK58_04365	COG3384	dioxygenase
AMK58_04375	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AMK58_04380	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AMK58_04385	COG0356	it plays a direct role in the translocation of protons across the membrane
AMK58_04395	COG1999	signal sequence binding
AMK58_04405	COG0840	transmembrane signaling receptor activity
AMK58_04410	COG1702	phosphate starvation-inducible protein PhoH
AMK58_04415	COG0850	regulation of cytokinetic process
AMK58_04420	COG2894	cell division
AMK58_04425	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AMK58_04440	COG0840	transmembrane signaling receptor activity
AMK58_04450	COG4948	Mandelate Racemase Muconate Lactonizing
AMK58_04460	COG1104	cysteine desulfurase activity
AMK58_04470	COG2154	pterin-4-alpha-carbinolamine dehydratase
AMK58_04485	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AMK58_04500	COG0840	transmembrane signaling receptor activity
AMK58_04505	COG0840	transmembrane signaling receptor activity
AMK58_04510	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AMK58_04515	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AMK58_04520	COG1278	Cold shock
AMK58_04530	COG5002	protein histidine kinase activity
AMK58_04530	COG0784	Response regulator, receiver
AMK58_04530	COG2205	protein histidine kinase activity
AMK58_04555	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AMK58_04610	COG5420	small protein containing a coiled-coil domain
AMK58_04625	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AMK58_04630	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AMK58_04685	COG0121	glutamine amidotransferase
AMK58_04700	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AMK58_04725	COG5554	nitrogen fixation
AMK58_04740	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AMK58_04765	COG1309	transcriptional regulator
AMK58_04775	COG1131	(ABC) transporter
AMK58_04785	COG0842	Transport permease protein
AMK58_04790	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
AMK58_04800	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AMK58_04805	COG0277	FAD linked oxidase domain protein
AMK58_04810	COG0277	FAD linked oxidase domain protein
AMK58_04815	COG0247	lactate metabolic process
AMK58_04835	COG1960	acyl-CoA dehydrogenase activity
AMK58_04850	COG0277	FAD linked oxidase domain protein
AMK58_04855	COG0009	L-threonylcarbamoyladenylate synthase
AMK58_04860	COG1192	Involved in chromosome partitioning
AMK58_04870	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AMK58_04875	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AMK58_04890	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AMK58_04895	COG2945	thiolester hydrolase activity
AMK58_04900	COG1045	serine acetyltransferase
AMK58_04915	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AMK58_04920	COG0633	Ferredoxin
AMK58_04925	COG0482	sulfurtransferase activity
AMK58_04940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMK58_04965	COG4221	oxidoreductase activity
AMK58_04975	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AMK58_04985	COG0784	Response regulator, receiver
AMK58_04985	COG2205	protein histidine kinase activity
AMK58_04995	COG0745	RESPONSE REGULATOR receiver
AMK58_05020	COG0432	Pfam Uncharacterised protein family UPF0047
AMK58_05030	COG2951	lytic endotransglycosylase activity
AMK58_05050	COG1454	alcohol dehydrogenase
AMK58_05080	COG0456	acetyltransferase
AMK58_05095	COG0114	fumarate hydratase activity
AMK58_05110	COG5001	Diguanylate cyclase
AMK58_05110	COG5002	protein histidine kinase activity
AMK58_05115	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AMK58_05130	COG0205	6-phosphofructokinase activity
AMK58_05160	COG0288	reversible hydration of carbon dioxide
AMK58_05220	COG0318	PFAM AMP-dependent synthetase and ligase
AMK58_05250	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AMK58_05255	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AMK58_05260	COG0343	queuine tRNA-ribosyltransferase activity
AMK58_05265	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AMK58_05270	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AMK58_05275	COG0840	transmembrane signaling receptor activity
AMK58_05345	COG2201	protein-glutamate methylesterase activity
AMK58_05375	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AMK58_05380	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AMK58_05385	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AMK58_05395	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AMK58_05400	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AMK58_05405	COG0242	peptide deformylase activity
AMK58_05415	COG3070	regulator of competence-specific genes
AMK58_05425	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
AMK58_05450	COG4120	Belongs to the binding-protein-dependent transport system permease family
AMK58_05455	COG0410	ABC transporter
AMK58_05465	COG0489	protein tyrosine kinase activity
AMK58_05470	COG0330	HflC and HflK could
AMK58_05475	COG0330	HflC and HflK could
AMK58_05500	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AMK58_05505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMK58_05510	COG0028	Belongs to the TPP enzyme family
AMK58_05525	COG0704	Plays a role in the regulation of phosphate uptake
AMK58_05530	COG2862	Uncharacterized protein family, UPF0114
AMK58_05550	COG0768	penicillin binding
AMK58_05555	COG0840	transmembrane signaling receptor activity
AMK58_05590	COG0295	cytidine deaminase activity
AMK58_05595	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AMK58_05600	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AMK58_05615	COG0697	spore germination
AMK58_05635	COG0411	ABC transporter
AMK58_05650	COG0038	chloride channel
AMK58_05660	COG2326	polyphosphate kinase activity
AMK58_05665	COG0366	Alpha amylase catalytic
AMK58_05675	COG2199	diguanylate cyclase activity
AMK58_05675	COG2203	Gaf domain
AMK58_05675	COG2200	EAL domain
AMK58_05685	COG2135	peptidase activity
AMK58_05695	COG0784	Response regulator, receiver
AMK58_05700	COG2261	transglycosylase associated protein
AMK58_05705	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AMK58_05720	COG1733	regulation of RNA biosynthetic process
AMK58_05730	COG2084	Dehydrogenase
AMK58_05735	COG1028	Short-chain dehydrogenase reductase Sdr
AMK58_05750	COG0546	phosphoglycolate phosphatase activity
AMK58_05765	COG0521	Mo-molybdopterin cofactor biosynthetic process
AMK58_05775	COG2832	Protein of unknown function (DUF454)
AMK58_05780	COG1238	metal cluster binding
AMK58_05785	COG3852	Histidine kinase
AMK58_05790	COG0469	pyruvate kinase activity
AMK58_05795	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AMK58_05810	COG0203	ribosomal protein L17
AMK58_05815	COG1238	metal cluster binding
AMK58_05830	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AMK58_05840	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AMK58_05845	COG0564	pseudouridine synthase activity
AMK58_05850	COG1802	Transcriptional regulator
AMK58_05855	COG3135	benzoate transporter
AMK58_05860	COG0546	phosphoglycolate phosphatase activity
AMK58_05885	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AMK58_05890	COG1129	ABC transporter
AMK58_05930	COG3706	GGDEF domain
AMK58_05930	COG0745	RESPONSE REGULATOR receiver
AMK58_05935	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AMK58_05940	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AMK58_05955	COG1028	Short-chain dehydrogenase reductase Sdr
AMK58_05960	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AMK58_05965	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AMK58_05975	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AMK58_05980	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AMK58_05985	COG0351	phosphomethylpyrimidine kinase
AMK58_05990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMK58_06005	COG0670	Belongs to the BI1 family
AMK58_06010	COG4325	translation initiation factor activity
AMK58_06030	COG1012	belongs to the aldehyde dehydrogenase family
AMK58_06030	COG2030	dehydratase
AMK58_06035	COG0443	Heat shock 70 kDa protein
AMK58_06060	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AMK58_06060	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AMK58_06110	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMK58_06115	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMK58_06125	COG0649	NAD binding
AMK58_06130	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AMK58_06140	COG1034	ATP synthesis coupled electron transport
AMK58_06145	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AMK58_06150	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMK58_06160	COG0713	ATP synthesis coupled electron transport
AMK58_06175	COG1007	ATP synthesis coupled electron transport
AMK58_06205	COG0519	Catalyzes the synthesis of GMP from XMP
AMK58_06220	COG0442	prolyl-tRNA aminoacylation
AMK58_06250	COG0587	DNA-directed DNA polymerase activity
AMK58_06255	COG0052	Belongs to the universal ribosomal protein uS2 family
AMK58_06260	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AMK58_06265	COG0528	UMP kinase activity
AMK58_06270	COG0233	cytoplasmic translational termination
AMK58_06275	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AMK58_06280	COG0575	Belongs to the CDS family
AMK58_06285	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AMK58_06290	COG0750	zinc metalloprotease
AMK58_06310	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AMK58_06315	COG3494	Protein of unknown function (DUF1009)
AMK58_06320	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AMK58_06335	COG0583	DNA-binding transcription factor activity
AMK58_06350	COG0372	Belongs to the citrate synthase family
AMK58_06355	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AMK58_06360	COG2333	competence protein COMEC
AMK58_06360	COG0658	competence protein
AMK58_06365	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AMK58_06370	COG0303	'Molybdopterin
AMK58_06375	COG0315	cyclic pyranopterin monophosphate synthase activity
AMK58_06420	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AMK58_06430	COG0149	triose-phosphate isomerase activity
AMK58_06460	COG0535	radical SAM domain protein
AMK58_06465	COG0535	radical SAM domain protein
AMK58_06470	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
AMK58_06475	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AMK58_06485	COG0148	phosphopyruvate hydratase activity
AMK58_06495	COG0037	tRNA processing
AMK58_06530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMK58_06550	COG0596	Alpha beta hydrolase
AMK58_06555	COG0728	peptidoglycan biosynthetic process
AMK58_06565	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AMK58_06580	COG0436	Aminotransferase
AMK58_06600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AMK58_06605	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AMK58_06630	COG0745	RESPONSE REGULATOR receiver
AMK58_06635	COG0840	transmembrane signaling receptor activity
AMK58_06670	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AMK58_06700	COG1832	CoA-binding protein
AMK58_06705	COG1024	Enoyl-CoA hydratase
AMK58_06715	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AMK58_06720	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AMK58_06725	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AMK58_06730	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AMK58_06735	COG2885	chlorophyll binding
AMK58_06735	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AMK58_06740	COG3243	poly(R)-hydroxyalkanoic acid synthase
AMK58_06755	COG2814	Major facilitator Superfamily
AMK58_06765	COG0436	Aminotransferase
AMK58_06775	COG1494	fructose-1,6-bisphosphatase
AMK58_06780	COG0371	Dehydrogenase
AMK58_06785	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AMK58_06785	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AMK58_06845	COG0656	L-ascorbic acid biosynthetic process
AMK58_06870	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AMK58_06875	COG0517	IMP dehydrogenase activity
AMK58_06880	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AMK58_06885	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AMK58_06890	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AMK58_06910	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AMK58_06915	COG0045	succinate-CoA ligase (ADP-forming) activity
AMK58_06925	COG2814	Major facilitator Superfamily
AMK58_06940	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AMK58_06955	COG2084	Dehydrogenase
AMK58_06960	COG3622	Belongs to the hyi family
AMK58_06965	COG3960	tartronate-semialdehyde synthase activity
AMK58_06970	COG0352	thiamine-phosphate diphosphorylase activity
AMK58_06970	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AMK58_06975	COG1802	Transcriptional regulator
AMK58_06980	COG0469	pyruvate kinase activity
AMK58_06990	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AMK58_06990	COG0574	Belongs to the PEP-utilizing enzyme family
AMK58_07015	COG3283	Transcriptional regulator of aromatic amino acids metabolism
AMK58_07020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMK58_07030	COG0693	protein deglycase activity
AMK58_07035	COG2197	response regulator
AMK58_07040	COG2197	response regulator
AMK58_07055	COG0829	nickel cation binding
AMK58_07060	COG0831	urea catabolic process
AMK58_07065	COG0832	Belongs to the urease beta subunit family
AMK58_07070	COG0804	urea catabolic process
AMK58_07075	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AMK58_07080	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AMK58_07085	COG0830	nickel cation binding
AMK58_07090	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AMK58_07095	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
AMK58_07105	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AMK58_07120	COG0640	Transcriptional regulator
AMK58_07150	COG1396	sequence-specific DNA binding
AMK58_07175	COG1846	Transcriptional regulator
AMK58_07185	COG0704	Plays a role in the regulation of phosphate uptake
AMK58_07205	COG0463	Glycosyl transferase, family 2
AMK58_07225	COG1940	carbohydrate kinase activity
AMK58_07250	COG0410	ABC transporter
AMK58_07275	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AMK58_07275	COG2885	chlorophyll binding
AMK58_07280	COG2197	response regulator
AMK58_07285	COG2205	protein histidine kinase activity
AMK58_07285	COG2198	Histidine kinase
AMK58_07285	COG0784	Response regulator, receiver
AMK58_07300	COG0564	pseudouridine synthase activity
AMK58_07305	COG1028	Short-chain dehydrogenase reductase Sdr
AMK58_07310	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AMK58_07325	COG0024	Methionine aminopeptidase
AMK58_07340	COG1127	ABC transporter
AMK58_07345	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AMK58_07350	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AMK58_07355	COG0305	Participates in initiation and elongation during chromosome replication
AMK58_07360	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AMK58_07365	COG0359	binds to the 23S rRNA
AMK58_07375	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AMK58_07380	COG0360	Binds together with S18 to 16S ribosomal RNA
AMK58_07385	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AMK58_07400	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AMK58_07405	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AMK58_07415	COG0741	lytic transglycosylase activity
AMK58_07420	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AMK58_07425	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AMK58_07430	COG2813	Specifically methylates the guanine in position
AMK58_07440	COG1881	PFAM PEBP family protein
AMK58_07445	COG0113	porphobilinogen synthase activity
AMK58_07450	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AMK58_07455	COG1597	lipid kinase activity
AMK58_07460	COG1024	Enoyl-CoA hydratase
AMK58_07465	COG1846	Transcriptional regulator
AMK58_07485	COG0559	Belongs to the binding-protein-dependent transport system permease family
AMK58_07500	COG0686	Belongs to the AlaDH PNT family
AMK58_07510	COG0737	Belongs to the 5'-nucleotidase family
AMK58_07515	COG0512	Glutamine amidotransferase of anthranilate synthase
AMK58_07520	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AMK58_07525	COG3608	succinylglutamate desuccinylase aspartoacylase
AMK58_07525	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AMK58_07590	COG0123	including yeast histone deacetylase and acetoin utilization protein
AMK58_07635	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AMK58_07640	COG0626	cystathionine gamma-synthase activity
AMK58_07645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMK58_07650	COG4597	amino acid ABC transporter
AMK58_07655	COG0765	amino acid transport
AMK58_07660	COG1126	abc transporter atp-binding protein
AMK58_07665	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AMK58_07685	COG2897	thiosulfate sulfurtransferase activity
AMK58_07700	COG0494	nUDIX hydrolase
AMK58_07705	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMK58_07730	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AMK58_07740	COG1538	Outer membrane efflux protein
AMK58_07750	COG0525	valine-tRNA ligase activity
AMK58_07755	COG0840	transmembrane signaling receptor activity
AMK58_07770	COG1686	Belongs to the peptidase S11 family
AMK58_07775	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AMK58_07780	COG0470	DNA polymerase III
AMK58_07785	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMK58_07790	COG0084	hydrolase, TatD family'
AMK58_07795	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AMK58_07795	COG0321	lipoyl(octanoyl) transferase activity
AMK58_07810	COG0631	protein serine/threonine phosphatase activity
AMK58_07820	COG2957	Belongs to the agmatine deiminase family
AMK58_07825	COG1177	transmembrane transport
AMK58_07830	COG1176	ABC-type spermidine putrescine transport system, permease component I
AMK58_07835	COG3842	ATPase activity
AMK58_07845	COG0174	glutamine synthetase
AMK58_07850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMK58_07880	COG0861	Integral membrane protein TerC family
AMK58_07890	COG4957	zinc ion binding
AMK58_07900	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AMK58_07925	COG1280	lysine exporter protein (LysE YggA)
AMK58_07935	COG0314	molybdopterin synthase activity
AMK58_07940	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AMK58_07950	COG1763	Mo-molybdopterin cofactor biosynthetic process
AMK58_07955	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AMK58_07965	COG1028	Short-chain dehydrogenase reductase Sdr
AMK58_08010	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AMK58_08010	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AMK58_08015	COG1160	GTP binding
AMK58_08035	COG2197	response regulator
AMK58_08045	COG2197	response regulator
AMK58_08075	COG0840	transmembrane signaling receptor activity
AMK58_08085	COG3706	GGDEF domain
AMK58_08085	COG0745	RESPONSE REGULATOR receiver
AMK58_08115	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AMK58_08120	COG2814	Major facilitator Superfamily
AMK58_08135	COG0789	Transcriptional regulator
AMK58_08140	COG0318	PFAM AMP-dependent synthetase and ligase
AMK58_08160	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AMK58_08170	COG1116	anion transmembrane transporter activity
AMK58_08170	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AMK58_08180	COG0175	sulfate reduction
AMK58_08185	COG0175	sulfate reduction
AMK58_08190	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AMK58_08190	COG1648	precorrin-2 dehydrogenase activity
AMK58_08205	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AMK58_08220	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AMK58_08220	COG4651	solute:proton antiporter activity
AMK58_08245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AMK58_08250	COG0416	fatty acid biosynthetic process
AMK58_08255	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AMK58_08275	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AMK58_08285	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AMK58_08290	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AMK58_08295	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AMK58_08300	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AMK58_08300	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AMK58_08310	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AMK58_08310	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AMK58_08315	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AMK58_08320	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AMK58_08325	COG0698	ribose 5-phosphate isomerase
AMK58_08345	COG3685	Protein conserved in bacteria
AMK58_08365	COG2153	protein acetylation
AMK58_08375	COG1793	dna ligase
AMK58_08385	COG2313	pseudouridylate synthase activity
AMK58_08395	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AMK58_08440	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMK58_08460	COG1755	Isoprenylcysteine carboxyl methyltransferase
AMK58_08465	COG3424	synthase
AMK58_08485	COG3328	transposase activity
AMK58_08490	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AMK58_08495	COG1492	cobalamin metabolic process
AMK58_08555	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AMK58_08565	COG1024	Enoyl-CoA hydratase
AMK58_08575	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AMK58_08580	COG3411	Ferredoxin
AMK58_08600	COG3546	catalase activity
AMK58_08605	COG2211	Major facilitator Superfamily
AMK58_08610	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AMK58_08655	COG0546	phosphoglycolate phosphatase activity
AMK58_08670	COG3108	Peptidase M15
AMK58_08680	COG1773	rubredoxin
AMK58_08695	COG1752	Esterase of the alpha-beta hydrolase superfamily
AMK58_08700	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
AMK58_08720	COG2205	protein histidine kinase activity
AMK58_08720	COG2202	Pas domain
AMK58_08750	COG2824	Alkylphosphonate utilization operon protein PhnA
AMK58_08755	COG0840	transmembrane signaling receptor activity
AMK58_08765	COG0243	molybdopterin cofactor binding
AMK58_08770	COG2070	2-Nitropropane dioxygenase
AMK58_08775	COG3706	GGDEF domain
AMK58_08790	COG1410	methionine synthase
AMK58_08790	COG0646	methionine synthase
AMK58_08810	COG2853	Lipoprotein
AMK58_08825	COG0488	(ABC) transporter
AMK58_08830	COG1671	Belongs to the UPF0178 family
AMK58_08835	COG5002	protein histidine kinase activity
AMK58_08835	COG2176	DNA-directed DNA polymerase activity
AMK58_08860	COG1640	4-alpha-glucanotransferase
AMK58_08865	COG0745	RESPONSE REGULATOR receiver
AMK58_08875	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AMK58_08880	COG0366	Alpha amylase catalytic
AMK58_08895	COG1218	3'(2'),5'-bisphosphate nucleotidase
AMK58_08900	COG2833	Protein of unknown function (DUF455)
AMK58_08915	COG1960	acyl-CoA dehydrogenase activity
AMK58_08920	COG1028	Short-chain dehydrogenase reductase Sdr
AMK58_08925	COG0318	PFAM AMP-dependent synthetase and ligase
AMK58_08930	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMK58_08935	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AMK58_08980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMK58_08990	COG1846	Transcriptional regulator
AMK58_08995	COG2267	carboxylic ester hydrolase activity
AMK58_09010	COG2226	methyltransferase
AMK58_09020	COG1201	RNA secondary structure unwinding
AMK58_09030	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AMK58_09035	COG0415	Belongs to the DNA photolyase family
AMK58_09045	COG0735	belongs to the Fur family
AMK58_09050	COG0523	cobalamin synthesis protein
AMK58_09060	COG0463	Glycosyl transferase, family 2
AMK58_09065	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AMK58_09070	COG1234	tRNA 3'-trailer cleavage
AMK58_09085	COG0840	transmembrane signaling receptor activity
AMK58_09100	COG4520	surface antigen
AMK58_09105	COG0484	heat shock protein binding
AMK58_09130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMK58_09130	COG4191	Histidine kinase
AMK58_09145	COG3437	response regulator, receiver
AMK58_09145	COG0784	Response regulator, receiver
AMK58_09170	COG2076	Multidrug Resistance protein
AMK58_09175	COG0300	oxidoreductase activity
AMK58_09180	COG1765	OsmC-like protein
AMK58_09190	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AMK58_09200	COG0697	spore germination
AMK58_09205	COG0367	asparagine synthase
AMK58_09220	COG0438	transferase activity, transferring glycosyl groups
AMK58_09225	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AMK58_09235	COG1086	Polysaccharide biosynthesis protein
AMK58_09245	COG2885	chlorophyll binding
AMK58_09260	COG0848	biopolymer transport protein
AMK58_09270	COG0824	Thioesterase
AMK58_09275	COG2255	four-way junction helicase activity
AMK58_09290	COG0217	transcriptional regulatory protein
AMK58_09295	COG1692	metallophosphoesterase
AMK58_09300	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AMK58_09340	COG1830	Aldolase
AMK58_09345	COG0352	thiamine-phosphate diphosphorylase activity
AMK58_09350	COG0730	response to heat
AMK58_09355	COG2067	long-chain fatty acid transport protein
AMK58_09360	COG0604	alcohol dehydrogenase
AMK58_09365	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AMK58_09370	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AMK58_09375	COG0483	inositol monophosphate 1-phosphatase activity
AMK58_09395	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AMK58_09400	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AMK58_09405	COG0509	glycine decarboxylation via glycine cleavage system
AMK58_09410	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AMK58_09425	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AMK58_09430	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AMK58_09440	COG0318	PFAM AMP-dependent synthetase and ligase
AMK58_09445	COG0678	peroxiredoxin activity
AMK58_09450	COG4232	protein-disulfide reductase activity
AMK58_09455	COG1678	Uncharacterized ACR, COG1678
AMK58_09465	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AMK58_09470	COG0612	Peptidase, M16
AMK58_09480	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AMK58_09485	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AMK58_09490	COG3346	SURF1 family
AMK58_09510	COG0109	protoheme IX farnesyltransferase activity
AMK58_09515	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AMK58_09520	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AMK58_09520	COG1565	acr, cog1565
AMK58_09530	COG0312	modulator of DNA gyrase
AMK58_09535	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AMK58_09540	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AMK58_09550	COG5487	UPF0391 membrane protein
AMK58_09560	COG0741	lytic transglycosylase activity
AMK58_09590	COG0564	pseudouridine synthase activity
AMK58_09595	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AMK58_09605	COG3266	domain, Protein
AMK58_09605	COG0515	serine threonine protein kinase
AMK58_09610	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AMK58_09615	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AMK58_09625	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AMK58_09640	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AMK58_09645	COG1295	ribonuclease BN
AMK58_09650	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AMK58_09660	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AMK58_09670	COG0745	RESPONSE REGULATOR receiver
AMK58_09680	COG0616	signal peptide processing
AMK58_09695	COG5002	protein histidine kinase activity
AMK58_09695	COG2198	Histidine kinase
AMK58_09695	COG0784	Response regulator, receiver
AMK58_09705	COG0390	transport system, permease component
AMK58_09710	COG0577	efflux transmembrane transporter activity
AMK58_09710	COG1136	(ABC) transporter
AMK58_09720	COG0628	permease
AMK58_09725	COG2205	protein histidine kinase activity
AMK58_09735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMK58_09745	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AMK58_09750	COG0251	oxidation-reduction process
AMK58_09760	COG0551	DNA topoisomerase type I activity
AMK58_09760	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AMK58_09790	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AMK58_09800	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AMK58_09820	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AMK58_09820	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AMK58_09830	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AMK58_09845	COG0505	Belongs to the CarA family
AMK58_09855	COG1403	HNH endonuclease
AMK58_09865	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AMK58_09870	COG1393	Belongs to the ArsC family
AMK58_09875	COG2890	protein-(glutamine-N5) methyltransferase activity
AMK58_09880	COG1214	PFAM Peptidase M22, glycoprotease
AMK58_09880	COG0456	acetyltransferase
AMK58_09920	COG0538	isocitrate dehydrogenase activity
AMK58_09930	COG3932	Exopolysaccharide synthesis, ExoD
AMK58_09950	COG0473	3-isopropylmalate dehydrogenase activity
AMK58_09980	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AMK58_10000	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AMK58_10015	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AMK58_10035	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AMK58_10040	COG1684	flagellar biosynthetic protein fliR
AMK58_10045	COG1987	bacterial-type flagellum assembly
AMK58_10050	COG1677	Flagellar hook-basal body complex protein FliE
AMK58_10055	COG1558	bacterial-type flagellum-dependent cell motility
AMK58_10060	COG1815	bacterial-type flagellum-dependent cell motility
AMK58_10065	COG2257	FlhB HrpN YscU SpaS Family
AMK58_10080	COG1338	Plays a role in the flagellum-specific transport system
AMK58_10095	COG1360	Flagellar Motor Protein
AMK58_10135	COG4786	Flagellar basal body rod
AMK58_10140	COG4786	Flagellar basal body rod
AMK58_10150	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AMK58_10160	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AMK58_10190	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AMK58_10215	COG0500	methyltransferase
AMK58_10225	COG1132	(ABC) transporter
AMK58_10230	COG0254	rRNA binding
AMK58_10240	COG0071	Belongs to the small heat shock protein (HSP20) family
AMK58_10260	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AMK58_10275	COG2186	Transcriptional regulator
AMK58_10280	COG0563	adenylate kinase activity
AMK58_10285	COG0201	protein transport
AMK58_10290	COG0200	Binds to the 23S rRNA
AMK58_10295	COG1841	ribosomal large subunit assembly
AMK58_10310	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AMK58_10315	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AMK58_10320	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AMK58_10330	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AMK58_10340	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AMK58_10345	COG0255	Belongs to the universal ribosomal protein uL29 family
AMK58_10350	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AMK58_10355	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AMK58_10360	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AMK58_10365	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AMK58_10370	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AMK58_10375	COG0089	rRNA binding
AMK58_10380	COG0088	Forms part of the polypeptide exit tunnel
AMK58_10390	COG0051	transcription antitermination factor activity, RNA binding
AMK58_10395	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AMK58_10405	COG0049	tRNA binding
AMK58_10420	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AMK58_10425	COG0085	RNA polymerase activity
AMK58_10430	COG0222	ribosome binding
AMK58_10435	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AMK58_10440	COG0081	regulation of translation
AMK58_10445	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AMK58_10465	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AMK58_10530	COG0410	ABC transporter
AMK58_10545	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AMK58_10555	COG1940	carbohydrate kinase activity
AMK58_10570	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AMK58_10575	COG0410	ABC transporter
AMK58_10580	COG0411	ABC transporter
AMK58_10590	COG0559	Belongs to the binding-protein-dependent transport system permease family
AMK58_10610	COG0673	inositol 2-dehydrogenase activity
AMK58_10620	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AMK58_10630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AMK58_10635	COG1309	transcriptional regulator
AMK58_10645	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AMK58_10665	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AMK58_10705	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AMK58_10710	COG0860	N-Acetylmuramoyl-L-alanine amidase
AMK58_10715	COG1530	ribonuclease E activity
AMK58_10755	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AMK58_10770	COG2264	protein methyltransferase activity
AMK58_10780	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AMK58_10795	COG0312	modulator of DNA gyrase
AMK58_10805	COG1597	lipid kinase activity
AMK58_10815	COG0438	transferase activity, transferring glycosyl groups
AMK58_10825	COG1519	Transferase
AMK58_10830	COG1663	tetraacyldisaccharide 4'-kinase activity
AMK58_10865	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AMK58_10875	COG0590	tRNA wobble adenosine to inosine editing
AMK58_10900	COG2703	oxygen carrier activity
AMK58_10905	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AMK58_10930	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AMK58_10940	COG2030	dehydratase
AMK58_10945	COG0196	riboflavin kinase activity
AMK58_10950	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AMK58_10955	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AMK58_10960	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AMK58_10970	COG0612	Peptidase, M16
AMK58_10975	COG0612	Peptidase, M16
AMK58_10985	COG0166	Belongs to the GPI family
AMK58_11005	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AMK58_11025	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AMK58_11040	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AMK58_11065	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AMK58_11070	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AMK58_11095	COG0179	Fumarylacetoacetate (FAA) hydrolase
AMK58_11100	COG2188	Transcriptional regulator
AMK58_11105	COG0667	Aldo Keto reductase
AMK58_11130	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AMK58_11135	COG1028	Short-chain dehydrogenase reductase Sdr
AMK58_11170	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AMK58_11180	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AMK58_11185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AMK58_11215	COG1309	transcriptional regulator
AMK58_11225	COG1518	maintenance of DNA repeat elements
AMK58_11265	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AMK58_11280	COG0742	ribosomal rna small subunit methyltransferase
AMK58_11285	COG1187	pseudouridine synthase activity
AMK58_11290	COG3360	Dodecin
AMK58_11295	COG0590	tRNA wobble adenosine to inosine editing
AMK58_11310	COG1570	exodeoxyribonuclease VII activity
AMK58_11320	COG0418	dihydroorotase activity
AMK58_11325	COG0124	histidyl-tRNA synthetase
AMK58_11365	COG1058	Belongs to the CinA family
AMK58_11365	COG1546	Belongs to the CinA family
AMK58_11370	COG1489	DNA binding
AMK58_11375	COG0024	Methionine aminopeptidase
AMK58_11395	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AMK58_11410	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AMK58_11415	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AMK58_11425	COG2258	MOSC domain
AMK58_11435	COG0583	DNA-binding transcription factor activity
AMK58_11440	COG0047	phosphoribosylformylglycinamidine synthase activity
AMK58_11445	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AMK58_11455	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AMK58_11465	COG2962	Rard protein
AMK58_11475	COG1902	pentaerythritol trinitrate reductase activity
AMK58_11480	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AMK58_11495	COG3279	Response regulator of the LytR AlgR family
AMK58_11505	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AMK58_11515	COG2205	protein histidine kinase activity
AMK58_11525	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AMK58_11555	COG0723	plastoquinol--plastocyanin reductase activity
AMK58_11570	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AMK58_11580	COG0463	Glycosyl transferase, family 2
AMK58_11585	COG0840	transmembrane signaling receptor activity
AMK58_11605	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AMK58_11645	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AMK58_11655	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AMK58_11665	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AMK58_11685	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AMK58_11685	COG2010	Cytochrome c
AMK58_11700	COG0799	negative regulation of ribosome biogenesis
AMK58_11705	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AMK58_11710	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AMK58_11720	COG0793	Belongs to the peptidase S41A family
AMK58_11730	COG1051	belongs to the nudix hydrolase family
AMK58_11750	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AMK58_11760	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AMK58_11780	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AMK58_11790	COG4974	Belongs to the 'phage' integrase family
AMK58_11795	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AMK58_11805	COG0596	Alpha beta hydrolase
AMK58_11825	COG4191	Histidine kinase
AMK58_11835	COG4106	trans-aconitate 2-methyltransferase activity
AMK58_11855	COG2226	methyltransferase
AMK58_11860	COG0126	phosphoglycerate kinase activity
AMK58_11870	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AMK58_11880	COG3474	cytochrome
AMK58_11885	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AMK58_11910	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AMK58_11915	COG4166	transmembrane transport
AMK58_11925	COG4166	transmembrane transport
AMK58_11930	COG4174	ABC transporter (Permease)
AMK58_11935	COG4239	(ABC) transporter, permease
AMK58_11940	COG4172	Belongs to the ABC transporter superfamily
AMK58_11975	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AMK58_11980	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AMK58_12005	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AMK58_12010	COG0587	DNA-directed DNA polymerase activity
AMK58_12025	COG4544	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
AMK58_12040	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AMK58_12045	COG0625	glutathione transferase activity
AMK58_12055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AMK58_12060	COG0601	transmembrane transport
AMK58_12085	COG0583	DNA-binding transcription factor activity
AMK58_12100	COG5001	Diguanylate cyclase
AMK58_12105	COG0625	glutathione transferase activity
AMK58_12110	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AMK58_12120	COG0156	8-amino-7-oxononanoate synthase activity
AMK58_12135	COG1028	Short-chain dehydrogenase reductase Sdr
AMK58_12150	COG1322	Protein conserved in bacteria
AMK58_12155	COG1278	Cold shock
AMK58_12165	COG0242	peptide deformylase activity
AMK58_12170	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AMK58_12175	COG0101	tRNA pseudouridine synthase activity
AMK58_12180	COG0559	Belongs to the binding-protein-dependent transport system permease family
AMK58_12195	COG2378	regulation of single-species biofilm formation
AMK58_12200	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AMK58_12215	COG0335	large ribosomal subunit rRNA binding
AMK58_12225	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AMK58_12230	COG0228	four-way junction DNA binding
AMK58_12235	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AMK58_12275	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AMK58_12290	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AMK58_12305	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AMK58_12315	COG1131	(ABC) transporter
AMK58_12325	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AMK58_12340	COG0489	protein tyrosine kinase activity
AMK58_12340	COG3206	protein involved in exopolysaccharide biosynthesis
AMK58_12350	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AMK58_12360	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMK58_12415	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AMK58_12425	COG0706	membrane insertase activity
AMK58_12430	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AMK58_12445	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AMK58_12455	COG0598	Magnesium transport protein CorA
AMK58_12470	COG0825	malonyl-CoA metabolic process
AMK58_12480	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AMK58_12485	COG4974	Belongs to the 'phage' integrase family
AMK58_12500	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AMK58_12505	COG0517	IMP dehydrogenase activity
AMK58_12520	COG0271	Belongs to the BolA IbaG family
AMK58_12550	COG1840	ABC-type Fe3 transport system, periplasmic component
AMK58_12555	COG1741	Belongs to the pirin family
AMK58_12560	COG1178	ABC-type Fe3 transport system permease component
AMK58_12565	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AMK58_12570	COG3706	GGDEF domain
AMK58_12570	COG0745	RESPONSE REGULATOR receiver
AMK58_12575	COG0135	phosphoribosylanthranilate isomerase activity
AMK58_12595	COG2423	ornithine cyclodeaminase activity
AMK58_12605	COG0776	regulation of translation
AMK58_12615	COG0539	negative regulation of cytoplasmic translation
AMK58_12630	COG0405	Gamma-glutamyltransferase
AMK58_12650	COG1741	Belongs to the pirin family
AMK58_12665	COG3706	GGDEF domain
AMK58_12665	COG0745	RESPONSE REGULATOR receiver
AMK58_12670	COG5002	protein histidine kinase activity
AMK58_12670	COG2205	protein histidine kinase activity
AMK58_12670	COG0784	Response regulator, receiver
AMK58_12680	COG0463	Glycosyl transferase, family 2
AMK58_12690	COG0071	Belongs to the small heat shock protein (HSP20) family
AMK58_12720	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AMK58_12745	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AMK58_12770	COG3162	membrane
AMK58_12785	COG1971	Probably functions as a manganese efflux pump
AMK58_12790	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AMK58_12795	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AMK58_12800	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AMK58_12805	COG1987	bacterial-type flagellum assembly
AMK58_12830	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AMK58_12835	COG0513	Belongs to the DEAD box helicase family
AMK58_12840	COG1970	mechanosensitive ion channel activity
AMK58_12845	COG0653	protein targeting
AMK58_12850	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AMK58_12855	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AMK58_12865	COG0494	nUDIX hydrolase
AMK58_12870	COG0514	ATP-dependent DNA helicase (RecQ)
AMK58_12900	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AMK58_12905	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AMK58_12935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMK58_12940	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AMK58_12945	COG0412	Dienelactone hydrolase
AMK58_12950	COG0033	Phosphoglucomutase
AMK58_12955	COG1278	Cold shock
AMK58_13005	COG0601	transmembrane transport
AMK58_13010	COG0747	negative chemotaxis
AMK58_13070	COG0671	phosphoesterase, PA-phosphatase related
AMK58_13080	COG3437	response regulator, receiver
AMK58_13080	COG0784	Response regulator, receiver
AMK58_13095	COG1983	PspC domain protein
AMK58_13105	COG1842	Phage shock protein A
AMK58_13110	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AMK58_13120	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AMK58_13135	COG3005	denitrification pathway
AMK58_13140	COG1858	cytochrome C peroxidase
AMK58_13145	COG0753	catalase activity
AMK58_13150	COG0459	protein refolding
AMK58_13155	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AMK58_13160	COG5425	PFAM Usg family protein
AMK58_13165	COG3772	lysozyme
AMK58_13170	COG0493	'glutamate synthase
AMK58_13170	COG0543	2 iron, 2 sulfur cluster binding
AMK58_13175	COG1612	heme a metabolic process
AMK58_13210	COG0668	transmembrane transport
AMK58_13215	COG3437	response regulator, receiver
AMK58_13215	COG0784	Response regulator, receiver
AMK58_13220	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AMK58_13235	COG1396	sequence-specific DNA binding
AMK58_13235	COG3800	Transcriptional regulator
AMK58_13240	COG2224	Isocitrate lyase
AMK58_13245	COG0693	protein deglycase activity
AMK58_13250	COG2202	Pas domain
AMK58_13250	COG2205	protein histidine kinase activity
AMK58_13255	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AMK58_13260	COG0674	pyruvate-flavodoxin oxidoreductase activity
AMK58_13260	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AMK58_13265	COG1013	pyruvate-flavodoxin oxidoreductase activity
AMK58_13285	COG3685	Protein conserved in bacteria
AMK58_13300	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AMK58_13315	COG0747	negative chemotaxis
AMK58_13380	COG4372	Transposase
AMK58_13385	COG3436	PFAM IS66 Orf2 family protein
AMK58_13390	COG3328	transposase activity
AMK58_13485	COG4372	Transposase
AMK58_13550	COG0464	growth
AMK58_13555	COG3485	protocatechuate 3,4-dioxygenase
AMK58_13590	COG2264	protein methyltransferase activity
AMK58_13645	COG0606	chelatase, subunit chli
AMK58_13670	COG0347	Belongs to the P(II) protein family
AMK58_13675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMK58_13680	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AMK58_13685	COG0667	Aldo Keto reductase
AMK58_13700	COG4181	ATPase activity
AMK58_13710	COG3706	GGDEF domain
AMK58_13720	COG0443	Heat shock 70 kDa protein
AMK58_13745	COG0745	RESPONSE REGULATOR receiver
AMK58_13755	COG1420	regulation of RNA biosynthetic process
AMK58_13760	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AMK58_13765	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AMK58_13770	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AMK58_13780	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AMK58_13805	COG0792	nuclease activity
AMK58_13810	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AMK58_13830	COG1366	Belongs to the anti-sigma-factor antagonist family
AMK58_13875	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AMK58_13905	COG2027	D-alanyl-D-alanine carboxypeptidase
AMK58_13915	COG2091	lysine biosynthetic process via aminoadipic acid
AMK58_13920	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AMK58_13925	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AMK58_13935	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AMK58_13935	COG2111	Na H antiporter
AMK58_13940	COG1006	Multisubunit Na H antiporter MnhC subunit
AMK58_13945	COG0651	ATP synthesis coupled electron transport
AMK58_13950	COG1863	multisubunit Na H antiporter MnhE subunit
AMK58_13955	COG2212	antiporter activity
AMK58_13960	COG1320	monovalent cation:proton antiporter activity
AMK58_14000	COG4615	Cyclic peptide transporter
AMK58_14035	COG0683	leucine binding
AMK58_14060	COG3842	ATPase activity
AMK58_14070	COG1175	transmembrane transport
AMK58_14090	COG1024	Enoyl-CoA hydratase
AMK58_14105	COG4221	oxidoreductase activity
AMK58_14110	COG1609	Transcriptional regulator
AMK58_14140	COG1966	Carbon starvation protein
AMK58_14145	COG2879	small protein
AMK58_14170	COG0765	amino acid transport
AMK58_14210	COG0840	transmembrane signaling receptor activity
AMK58_14250	COG2814	Major facilitator Superfamily
AMK58_14255	COG0583	DNA-binding transcription factor activity
AMK58_14265	COG4774	siderophore transport
AMK58_14270	COG1120	ATPase activity
AMK58_14285	COG1132	(ABC) transporter
AMK58_14305	COG0187	DNA topoisomerase II activity
AMK58_14310	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AMK58_14315	COG0592	DNA-directed DNA polymerase activity
AMK58_14355	COG4566	intracellular signal transduction
AMK58_14360	COG4191	Histidine kinase
AMK58_14365	COG1335	isochorismatase
AMK58_14425	COG0625	glutathione transferase activity
AMK58_14430	COG0583	DNA-binding transcription factor activity
AMK58_14435	COG4948	Mandelate Racemase Muconate Lactonizing
AMK58_14440	COG0288	reversible hydration of carbon dioxide
AMK58_14450	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AMK58_14475	COG0438	transferase activity, transferring glycosyl groups
AMK58_14515	COG1960	acyl-CoA dehydrogenase activity
AMK58_14525	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
AMK58_14540	COG0583	DNA-binding transcription factor activity
AMK58_14545	COG2080	2 iron, 2 sulfur cluster binding
AMK58_14550	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AMK58_14555	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AMK58_14560	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMK58_14585	COG1657	PFAM Prenyltransferase squalene oxidase
AMK58_14605	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AMK58_14620	COG2205	protein histidine kinase activity
AMK58_14625	COG3932	Exopolysaccharide synthesis, ExoD
AMK58_14630	COG1253	flavin adenine dinucleotide binding
AMK58_14650	COG0745	RESPONSE REGULATOR receiver
AMK58_14660	COG0772	Belongs to the SEDS family
AMK58_14680	COG0019	diaminopimelate decarboxylase activity
AMK58_14695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AMK58_14705	COG1250	3-hydroxyacyl-CoA dehydrogenase
AMK58_14715	COG2086	electron transfer activity
AMK58_14730	COG2723	6-phospho-beta-galactosidase activity
AMK58_14765	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AMK58_14785	COG1376	ErfK ybiS ycfS ynhG family protein
AMK58_14790	COG0559	Belongs to the binding-protein-dependent transport system permease family
AMK58_14800	COG1137	ATPase activity
AMK58_14805	COG0840	transmembrane signaling receptor activity
AMK58_14810	COG0795	lipopolysaccharide-transporting ATPase activity
AMK58_14835	COG1749	Flagellar hook protein flgE
AMK58_14860	COG0737	Belongs to the 5'-nucleotidase family
AMK58_14865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMK58_14870	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AMK58_14875	COG1309	transcriptional regulator
AMK58_14880	COG1028	Short-chain dehydrogenase reductase Sdr
AMK58_14885	COG0778	Nitroreductase
AMK58_14890	COG1797	cobyrinic acid a,c-diamide synthase activity
AMK58_14920	COG2099	Precorrin-6x reductase
AMK58_14980	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AMK58_14985	COG1028	Short-chain dehydrogenase reductase Sdr
AMK58_14990	COG0625	glutathione transferase activity
AMK58_15020	COG1640	4-alpha-glucanotransferase
AMK58_15060	COG1686	Belongs to the peptidase S11 family
AMK58_15075	COG1840	ABC-type Fe3 transport system, periplasmic component
AMK58_15080	COG4149	molybdate abc transporter
AMK58_15085	COG3842	ATPase activity
AMK58_15100	COG2391	methyltransferase activity
AMK58_15105	COG0583	DNA-binding transcription factor activity
AMK58_15110	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AMK58_15115	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AMK58_15140	COG0246	Mannitol dehydrogenase
AMK58_15145	COG2721	sulfolactate sulfo-lyase activity
AMK58_15150	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AMK58_15160	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AMK58_15165	COG1063	alcohol dehydrogenase
AMK58_15180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMK58_15190	COG1917	Cupin 2, conserved barrel domain protein
AMK58_15190	COG4977	sequence-specific DNA binding
AMK58_15210	COG2376	Dihydroxyacetone kinase
AMK58_15215	COG1414	Transcriptional regulator
AMK58_15220	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AMK58_15255	COG3547	Transposase (IS116 IS110 IS902 family)
AMK58_15350	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AMK58_15445	COG0714	Associated with various cellular activities
AMK58_15465	COG0617	tRNA 3'-terminal CCA addition
AMK58_15470	COG0408	coproporphyrinogen oxidase activity
AMK58_15475	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AMK58_15490	COG2857	Cytochrome c1
AMK58_15490	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AMK58_15510	COG0640	Transcriptional regulator
AMK58_15515	COG0425	Belongs to the sulfur carrier protein TusA family
AMK58_15535	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AMK58_15545	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AMK58_15555	COG0583	DNA-binding transcription factor activity
AMK58_15565	COG1028	Short-chain dehydrogenase reductase Sdr
AMK58_15570	COG1846	Transcriptional regulator
AMK58_15585	COG0583	DNA-binding transcription factor activity
AMK58_15595	COG0300	oxidoreductase activity
AMK58_15630	COG1396	sequence-specific DNA binding
AMK58_15645	COG3284	Transcriptional regulator
AMK58_15650	COG3199	ATP-NAD kinase
AMK58_15655	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AMK58_15660	COG0022	dehydrogenase e1 component
AMK58_15665	COG0596	Alpha beta hydrolase
AMK58_15665	COG0508	dehydrogenase complex catalyzes the overall conversion of
AMK58_15675	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AMK58_15685	COG1028	Short-chain dehydrogenase reductase Sdr
AMK58_15690	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AMK58_15710	COG1082	Xylose isomerase domain protein TIM barrel
AMK58_15720	COG0183	Belongs to the thiolase family
AMK58_15750	COG0559	Belongs to the binding-protein-dependent transport system permease family
AMK58_15755	COG0411	ABC transporter
AMK58_15780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMK58_15790	COG2205	protein histidine kinase activity
AMK58_15795	COG0745	RESPONSE REGULATOR receiver
AMK58_15805	COG1278	Cold shock
AMK58_15810	COG1846	Transcriptional regulator
AMK58_15815	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AMK58_15830	COG0556	nucleotide-excision repair
AMK58_15850	COG2205	protein histidine kinase activity
AMK58_15855	COG2927	DNA polymerase III (CHI subunit)
AMK58_15860	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AMK58_15870	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AMK58_15875	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AMK58_15890	COG0741	lytic transglycosylase activity
AMK58_15915	COG1561	YicC-like family, N-terminal region
AMK58_15920	COG0300	oxidoreductase activity
AMK58_15925	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AMK58_15930	COG3932	Exopolysaccharide synthesis, ExoD
AMK58_15935	COG0488	(ABC) transporter
AMK58_15940	COG0105	UTP biosynthetic process
AMK58_15950	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AMK58_15955	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AMK58_15965	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AMK58_15970	COG0628	permease
AMK58_15980	COG1028	Short-chain dehydrogenase reductase Sdr
AMK58_15985	COG3025	triphosphatase activity
AMK58_15995	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AMK58_16000	COG0248	Ppx GppA phosphatase
AMK58_16010	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AMK58_16015	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AMK58_16040	COG2205	protein histidine kinase activity
AMK58_16040	COG2202	Pas domain
AMK58_16050	COG0745	RESPONSE REGULATOR receiver
AMK58_16050	COG3706	GGDEF domain
AMK58_16055	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AMK58_16060	COG0793	Belongs to the peptidase S41A family
AMK58_16065	COG0557	exoribonuclease II activity
AMK58_16085	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AMK58_16115	COG5564	TIM-barrel signal transduction protein
AMK58_16120	COG5441	Belongs to the UPF0261 family
AMK58_16125	COG2204	response regulator
AMK58_16125	COG5564	TIM-barrel signal transduction protein
AMK58_16140	COG1902	pentaerythritol trinitrate reductase activity
AMK58_16140	COG0446	pyridine nucleotide-disulphide oxidoreductase
AMK58_16145	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AMK58_16170	COG0444	Belongs to the ABC transporter superfamily
AMK58_16180	COG0601	transmembrane transport
AMK58_16225	COG1845	cytochrome c oxidase, subunit III
AMK58_16230	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AMK58_16235	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AMK58_16270	COG0437	4 iron, 4 sulfur cluster binding
AMK58_16290	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AMK58_16295	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AMK58_16305	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AMK58_16310	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AMK58_16355	COG3264	Mechanosensitive ion channel
AMK58_16355	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AMK58_16365	COG2814	Major facilitator Superfamily
AMK58_16370	COG0386	Belongs to the glutathione peroxidase family
AMK58_16380	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AMK58_16385	COG0837	glucose binding
AMK58_16385	COG1737	Transcriptional regulator
AMK58_16390	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AMK58_16395	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AMK58_16400	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AMK58_16410	COG0179	Fumarylacetoacetate (FAA) hydrolase
AMK58_16425	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AMK58_16430	COG0758	DNA mediated transformation
AMK58_16450	COG2814	Major facilitator Superfamily
AMK58_16480	COG2205	protein histidine kinase activity
AMK58_16480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMK58_16485	COG0745	RESPONSE REGULATOR receiver
AMK58_16520	COG0581	inorganic phosphate transmembrane transporter activity
AMK58_16525	COG1176	ABC-type spermidine putrescine transport system, permease component I
AMK58_16535	COG3842	ATPase activity
AMK58_16545	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AMK58_16550	COG1732	Glycine betaine
AMK58_16555	COG1174	glycine betaine transport
AMK58_16560	COG1125	glycine betaine transport
AMK58_16565	COG1174	glycine betaine transport
AMK58_16575	COG1652	LysM domain
AMK58_16580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMK58_16590	COG1024	Enoyl-CoA hydratase
AMK58_16595	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AMK58_16600	COG1609	Transcriptional regulator
AMK58_16605	COG3265	gluconokinase activity
AMK58_16620	COG1609	Transcriptional regulator
AMK58_16625	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AMK58_16630	COG1126	abc transporter atp-binding protein
AMK58_16640	COG0765	amino acid transport
AMK58_16645	COG0765	amino acid transport
AMK58_16650	COG0303	'Molybdopterin
AMK58_16670	COG1028	Short-chain dehydrogenase reductase Sdr
AMK58_16675	COG0730	response to heat
AMK58_16690	COG0717	Belongs to the dCTP deaminase family
AMK58_16695	COG2188	Transcriptional regulator
AMK58_16700	COG0683	leucine binding
AMK58_16705	COG0559	Belongs to the binding-protein-dependent transport system permease family
AMK58_16740	COG1335	isochorismatase
AMK58_16750	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AMK58_16755	COG0066	3-isopropylmalate dehydratase activity
AMK58_16760	COG0745	RESPONSE REGULATOR receiver
AMK58_16760	COG3706	GGDEF domain
AMK58_16775	COG0708	Exodeoxyribonuclease III
AMK58_16780	COG0316	Belongs to the HesB IscA family
AMK58_16785	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AMK58_16800	COG1472	Belongs to the glycosyl hydrolase 3 family
AMK58_16805	COG1994	Peptidase M50
AMK58_16810	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AMK58_16815	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AMK58_16820	COG3842	ATPase activity
AMK58_16825	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AMK58_16830	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AMK58_16835	COG0805	protein transport
AMK58_16840	COG0745	RESPONSE REGULATOR receiver
AMK58_16840	COG3706	GGDEF domain
AMK58_16845	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AMK58_16855	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AMK58_16880	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AMK58_16890	COG3737	Protein of unknown function (DUF498/DUF598)
AMK58_16900	COG1233	COG1233 Phytoene dehydrogenase and related
AMK58_16905	COG1562	ergosterol biosynthetic process
AMK58_16910	COG1562	ergosterol biosynthetic process
AMK58_16925	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AMK58_16940	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AMK58_16945	COG0629	single-stranded DNA binding
AMK58_16975	COG0534	Mate efflux family protein
AMK58_16980	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AMK58_16985	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AMK58_17020	COG0129	dihydroxy-acid dehydratase activity
AMK58_17030	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AMK58_17050	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMK58_17055	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AMK58_17070	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AMK58_17075	COG3383	formate dehydrogenase (NAD+) activity
AMK58_17090	COG0583	DNA-binding transcription factor activity
AMK58_17095	COG2814	Major facilitator Superfamily
AMK58_17105	COG0697	spore germination
AMK58_17110	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AMK58_17145	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AMK58_17165	COG0308	aminopeptidase N
AMK58_17175	COG0316	Belongs to the HesB IscA family
AMK58_17185	COG0822	iron-sulfur transferase activity
AMK58_17190	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AMK58_17195	COG0719	Fe-S assembly protein
AMK58_17200	COG0396	ATPase activity
AMK58_17205	COG0719	Fe-S assembly protein
AMK58_17240	COG0745	RESPONSE REGULATOR receiver
AMK58_17245	COG5002	protein histidine kinase activity
AMK58_17290	COG0058	SHG alpha-glucan phosphorylase activity
AMK58_17295	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AMK58_17305	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AMK58_17310	COG4191	Histidine kinase
AMK58_17320	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AMK58_17325	COG1984	allophanate hydrolase subunit 2
AMK58_17330	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AMK58_17335	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AMK58_17350	COG4336	lyase activity
AMK58_17355	COG0583	DNA-binding transcription factor activity
AMK58_17365	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMK58_17400	COG0840	transmembrane signaling receptor activity
AMK58_17420	COG0366	Alpha amylase catalytic
AMK58_17425	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AMK58_17430	COG0625	glutathione transferase activity
AMK58_17435	COG4166	transmembrane transport
AMK58_17450	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AMK58_17455	COG0393	Putative heavy-metal-binding
AMK58_17485	COG1280	lysine exporter protein (LysE YggA)
AMK58_17495	COG2183	response to ionizing radiation
AMK58_17500	COG0651	ATP synthesis coupled electron transport
AMK58_17505	COG0650	Formate hydrogenlyase subunit 4
AMK58_17515	COG0651	ATP synthesis coupled electron transport
AMK58_17520	COG0649	NAD binding
AMK58_17525	COG3260	NADH ubiquinone oxidoreductase 20
AMK58_17530	COG3956	TIGRFAM MazG family protein
AMK58_17545	COG0483	inositol monophosphate 1-phosphatase activity
AMK58_17560	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AMK58_17565	COG1923	regulation of RNA biosynthetic process
AMK58_17580	COG0569	domain protein
AMK58_17590	COG2204	response regulator
AMK58_17625	COG1058	Belongs to the CinA family
AMK58_17625	COG1546	Belongs to the CinA family
AMK58_17630	COG2867	negative regulation of translational initiation
AMK58_17635	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AMK58_17640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AMK58_17645	COG0508	dehydrogenase complex catalyzes the overall conversion of
AMK58_17650	COG0508	dehydrogenase complex catalyzes the overall conversion of
AMK58_17650	COG0022	dehydrogenase e1 component
AMK58_17655	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AMK58_17660	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AMK58_17665	COG1607	acyl-coa hydrolase
AMK58_17670	COG0187	DNA topoisomerase II activity
AMK58_17680	COG0596	Alpha beta hydrolase
AMK58_17690	COG0513	Belongs to the DEAD box helicase family
AMK58_17700	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AMK58_17730	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AMK58_17735	COG2815	serine threonine protein kinase
AMK58_17735	COG0515	serine threonine protein kinase
AMK58_17740	COG2017	converts alpha-aldose to the beta-anomer
AMK58_17760	COG2010	Cytochrome c
AMK58_17765	COG2308	Evidence 4 Homologs of previously reported genes of
AMK58_17765	COG2307	Protein conserved in bacteria
AMK58_17775	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMK58_17780	COG1566	PFAM secretion protein HlyD family protein
AMK58_17785	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AMK58_17790	COG1216	Glycosyl transferase, family 2
AMK58_17795	COG0740	serine-type endopeptidase activity
AMK58_17815	COG3768	UPF0283 membrane protein
AMK58_17820	COG3106	COG3106 Predicted ATPase
AMK58_17825	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AMK58_17830	COG0571	ribonuclease III activity
AMK58_17835	COG0681	Belongs to the peptidase S26 family
AMK58_17840	COG0736	holo-[acyl-carrier-protein] synthase activity
AMK58_17845	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AMK58_17860	COG1758	RNA polymerase activity
AMK58_17875	COG3920	Histidine kinase
AMK58_17885	COG1846	Transcriptional regulator
AMK58_17895	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AMK58_17905	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AMK58_17920	COG3240	lipase activity
AMK58_17925	COG3038	cytochrome b561
AMK58_17935	COG0501	Belongs to the peptidase M48B family
AMK58_17955	COG0492	ferredoxin-NADP+ reductase activity
AMK58_17965	COG2197	response regulator
AMK58_17975	COG0435	Glutathione S-transferase
AMK58_17980	COG0655	NAD(P)H dehydrogenase (quinone) activity
AMK58_17985	COG0583	DNA-binding transcription factor activity
AMK58_17990	COG2264	protein methyltransferase activity
AMK58_18000	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AMK58_18025	COG4191	Histidine kinase
AMK58_18030	COG1132	(ABC) transporter
AMK58_18035	COG1752	Esterase of the alpha-beta hydrolase superfamily
AMK58_18065	COG5001	Diguanylate cyclase
AMK58_18070	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AMK58_18090	COG1666	GTP binding
AMK58_18120	COG4608	Belongs to the ABC transporter superfamily
AMK58_18125	COG0444	Belongs to the ABC transporter superfamily
AMK58_18130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AMK58_18135	COG0601	transmembrane transport
AMK58_18140	COG0747	negative chemotaxis
AMK58_18150	COG2226	methyltransferase
AMK58_18165	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AMK58_18180	COG1228	amidohydrolase
AMK58_18190	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AMK58_18215	COG0784	Response regulator, receiver
AMK58_18245	COG0860	N-Acetylmuramoyl-L-alanine amidase
AMK58_18265	COG0457	Tetratricopeptide repeat
AMK58_18265	COG0859	PFAM glycosyl transferase family 9
AMK58_18275	COG0457	Tetratricopeptide repeat
AMK58_18275	COG0859	PFAM glycosyl transferase family 9
AMK58_18290	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AMK58_18320	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
AMK58_18325	COG2089	acid synthase
AMK58_18350	COG1028	Short-chain dehydrogenase reductase Sdr
AMK58_18380	COG1294	oxidase, subunit
AMK58_18385	COG1271	oxidase subunit
AMK58_18390	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AMK58_18410	COG1127	ABC transporter
AMK58_18415	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AMK58_18420	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AMK58_18435	COG2703	oxygen carrier activity
AMK58_18470	COG0583	DNA-binding transcription factor activity
AMK58_18475	COG0667	Aldo Keto reductase
AMK58_18490	COG0583	DNA-binding transcription factor activity
AMK58_18505	COG0519	Catalyzes the synthesis of GMP from XMP
AMK58_18510	COG1247	-acetyltransferase
AMK58_18535	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AMK58_18545	COG3813	Protein conserved in bacteria
AMK58_18550	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AMK58_18550	COG0357	Ribosomal RNA small subunit methyltransferase G
AMK58_18585	COG0148	phosphopyruvate hydratase activity
AMK58_18605	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AMK58_18615	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AMK58_18620	COG1454	alcohol dehydrogenase
AMK58_18635	COG2267	carboxylic ester hydrolase activity
AMK58_18670	COG5002	protein histidine kinase activity
AMK58_18725	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AMK58_18755	COG2862	Uncharacterized protein family, UPF0114
AMK58_18865	COG3501	Rhs element vgr protein
AMK58_18880	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AMK58_18885	COG3806	Anti-sigma factor
AMK58_18890	COG1595	DNA-templated transcription, initiation
AMK58_18900	COG1882	Formate acetyltransferase
AMK58_18910	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AMK58_18910	COG3008	intermembrane lipid transfer
AMK58_18915	COG2995	paraquat-inducible protein a
AMK58_18925	COG0859	PFAM glycosyl transferase family 9
AMK58_18925	COG0457	Tetratricopeptide repeat
AMK58_18930	COG0281	malic enzyme
AMK58_18930	COG0280	phosphate acetyltransferase
AMK58_18935	COG1301	dicarboxylic acid transport
AMK58_18940	COG4191	Histidine kinase
AMK58_18945	COG2204	response regulator
AMK58_18965	COG1268	BioY protein
AMK58_18975	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AMK58_18985	COG1794	racemase activity, acting on amino acids and derivatives
AMK58_19000	COG4191	Histidine kinase
AMK58_19005	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AMK58_19010	COG0154	amidase activity
AMK58_19015	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AMK58_19025	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AMK58_19055	COG0583	DNA-binding transcription factor activity
AMK58_19070	COG0540	Belongs to the ATCase OTCase family
AMK58_19075	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AMK58_19080	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AMK58_19085	COG0745	RESPONSE REGULATOR receiver
AMK58_19105	COG1988	membrane-bound metal-dependent
AMK58_19115	COG2080	2 iron, 2 sulfur cluster binding
AMK58_19120	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AMK58_19125	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AMK58_19130	COG3634	alkyl hydroperoxide reductase activity
AMK58_19135	COG0450	alkyl hydroperoxide reductase
AMK58_19140	COG0583	DNA-binding transcription factor activity
AMK58_19150	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AMK58_19155	COG0287	Prephenate dehydrogenase
AMK58_19160	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AMK58_19170	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AMK58_19175	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AMK58_19175	COG2813	Specifically methylates the guanine in position
AMK58_19195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMK58_19200	COG0625	glutathione transferase activity
AMK58_19230	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AMK58_19245	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AMK58_19250	COG0437	4 iron, 4 sulfur cluster binding
AMK58_19255	COG5557	Pfam Polysulphide reductase, NrfD
AMK58_19260	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AMK58_19265	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AMK58_19270	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AMK58_19285	COG0298	carbon dioxide binding
AMK58_19300	COG0375	protein maturation
AMK58_19310	COG1280	lysine exporter protein (LysE YggA)
AMK58_19315	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AMK58_19320	COG0298	carbon dioxide binding
AMK58_19325	COG0309	Hydrogenase expression formation protein (HypE)
AMK58_19335	COG0793	Belongs to the peptidase S41A family
AMK58_19345	COG3012	SEC-C Motif Domain Protein
AMK58_19350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMK58_19350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AMK58_19360	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AMK58_19380	COG1194	a g-specific adenine glycosylase
AMK58_19395	COG1196	nuclear chromosome segregation
AMK58_19410	COG3047	cAMP biosynthetic process
AMK58_19425	COG1960	acyl-CoA dehydrogenase activity
AMK58_19430	COG1250	3-hydroxyacyl-CoA dehydrogenase
AMK58_19430	COG1024	Enoyl-CoA hydratase
AMK58_19435	COG0183	Belongs to the thiolase family
AMK58_19450	COG2373	Large extracellular alpha-helical protein
AMK58_19455	COG2205	protein histidine kinase activity
AMK58_19470	COG1766	The M ring may be actively involved in energy transduction
AMK58_19480	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AMK58_19485	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AMK58_19490	COG2204	response regulator
AMK58_19495	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AMK58_19500	COG0552	protein localization to endoplasmic reticulum
AMK58_19505	COG0455	bacterial-type flagellum organization
AMK58_19515	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AMK58_19535	COG1157	protein secretion by the type III secretion system
AMK58_19540	COG0745	RESPONSE REGULATOR receiver
AMK58_19550	COG0583	DNA-binding transcription factor activity
AMK58_19565	COG0745	RESPONSE REGULATOR receiver
AMK58_19570	COG0835	chemotaxis
AMK58_19575	COG2198	Histidine kinase
AMK58_19575	COG0643	Histidine kinase
AMK58_19600	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AMK58_19605	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AMK58_19610	COG1360	Flagellar Motor Protein
AMK58_19615	COG2308	Evidence 4 Homologs of previously reported genes of
AMK58_19625	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AMK58_19635	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AMK58_19640	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AMK58_19645	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AMK58_19650	COG1381	Involved in DNA repair and RecF pathway recombination
AMK58_19655	COG5001	Diguanylate cyclase
AMK58_19680	COG1309	transcriptional regulator
AMK58_19690	COG2884	Cell division ATP-binding protein ftsE
AMK58_19725	COG0586	Pfam SNARE associated Golgi protein
AMK58_19730	COG0505	Belongs to the CarA family
AMK58_19740	COG3135	benzoate transporter
AMK58_19745	COG0583	DNA-binding transcription factor activity
AMK58_19750	COG2249	NAD(P)H dehydrogenase (quinone) activity
AMK58_19765	COG0488	(ABC) transporter
AMK58_19775	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AMK58_19795	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AMK58_19805	COG0612	Peptidase, M16
AMK58_19835	COG2223	nitrite transmembrane transporter activity
AMK58_19845	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AMK58_19855	COG1392	Phosphate transport regulator
AMK58_19860	COG0306	phosphate transporter
AMK58_19895	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMK58_19920	COG1283	sodium-dependent phosphate transmembrane transporter activity
AMK58_19930	COG0583	DNA-binding transcription factor activity
AMK58_19980	COG0840	transmembrane signaling receptor activity
AMK58_20040	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMK58_20065	COG1573	uracil-dna glycosylase
AMK58_20070	COG0741	lytic transglycosylase activity
AMK58_20075	COG0521	Mo-molybdopterin cofactor biosynthetic process
AMK58_20090	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AMK58_20105	COG2217	Heavy metal translocating P-type atpase
AMK58_20130	COG1741	Belongs to the pirin family
AMK58_20135	COG2860	membrane
AMK58_20145	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AMK58_20150	COG0789	Transcriptional regulator
AMK58_20165	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AMK58_20210	COG1566	PFAM secretion protein HlyD family protein
AMK58_20220	COG0583	DNA-binding transcription factor activity
AMK58_20225	COG2814	Major facilitator Superfamily
AMK58_20235	COG0471	metal ion transport
AMK58_20235	COG3273	potassium ion transport
AMK58_20265	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AMK58_20275	COG0583	DNA-binding transcription factor activity
AMK58_20280	COG3842	ATPase activity
AMK58_20285	COG2182	Extracellular solute-binding protein
AMK58_20290	COG1176	ABC-type spermidine putrescine transport system, permease component I
AMK58_20300	COG1917	Cupin 2, conserved barrel domain protein
AMK58_20300	COG1396	sequence-specific DNA binding
AMK58_20310	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AMK58_20320	COG5507	3-demethylubiquinone-9 3-methyltransferase
AMK58_20335	COG1309	transcriptional regulator
AMK58_20350	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AMK58_20360	COG1522	sequence-specific DNA binding
AMK58_20365	COG1192	Involved in chromosome partitioning
AMK58_20395	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AMK58_20400	COG1530	ribonuclease E activity
AMK58_20410	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AMK58_20425	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AMK58_20435	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AMK58_20450	COG1464	Belongs to the NlpA lipoprotein family
AMK58_20455	COG0318	PFAM AMP-dependent synthetase and ligase
AMK58_20460	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AMK58_20465	COG2011	ABC-type metal ion transport system permease component
AMK58_20480	COG5002	protein histidine kinase activity
AMK58_20505	COG0588	phosphoglycerate mutase activity
AMK58_20510	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AMK58_20515	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AMK58_20525	COG3693	PFAM glycoside hydrolase, family 10
AMK58_20535	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AMK58_20555	COG1215	transferase activity, transferring glycosyl groups
AMK58_20560	COG0438	transferase activity, transferring glycosyl groups
AMK58_20565	COG0438	transferase activity, transferring glycosyl groups
AMK58_20580	COG0318	PFAM AMP-dependent synthetase and ligase
AMK58_20585	COG0367	asparagine synthase
AMK58_20590	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AMK58_20630	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AMK58_20635	COG4208	sulfate ABC transporter
AMK58_20645	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AMK58_20655	COG1959	2 iron, 2 sulfur cluster binding
AMK58_20660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMK58_20670	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AMK58_20705	COG3685	Protein conserved in bacteria
AMK58_20755	COG4206	TonB-dependent receptor
AMK58_20815	COG5002	protein histidine kinase activity
AMK58_20815	COG2205	protein histidine kinase activity
AMK58_20815	COG0784	Response regulator, receiver
AMK58_20830	COG1695	Transcriptional regulator
AMK58_20835	COG4607	ABC-type enterochelin transport system periplasmic component
AMK58_20840	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMK58_20845	COG4605	iron ion homeostasis
AMK58_20850	COG4604	ABC transporter, ATP-binding protein
AMK58_20865	COG3128	pkhd-type hydroxylase
AMK58_20870	COG4774	siderophore transport
AMK58_20875	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AMK58_20890	COG0671	phosphoesterase, PA-phosphatase related
AMK58_20895	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AMK58_20905	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AMK58_20910	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AMK58_20915	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AMK58_20920	COG0842	Transport permease protein
AMK58_20925	COG2137	regulation of response to DNA damage stimulus
AMK58_20935	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AMK58_20945	COG1703	isobutyryl-CoA mutase activity
AMK58_20955	COG5265	(ABC) transporter
AMK58_20975	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AMK58_20980	COG1272	protein, Hemolysin III
AMK58_20985	COG0542	response to heat
AMK58_21005	COG2890	protein-(glutamine-N5) methyltransferase activity
AMK58_21010	COG2852	Protein conserved in bacteria
AMK58_21020	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AMK58_21025	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AMK58_21040	COG2070	2-Nitropropane dioxygenase
AMK58_21045	COG0527	aspartate kinase activity
AMK58_21050	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AMK58_21055	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMK58_21060	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AMK58_21065	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AMK58_21070	COG1137	ATPase activity
AMK58_21105	COG2223	nitrite transmembrane transporter activity
AMK58_21150	COG0642	Histidine kinase
AMK58_21150	COG3850	Histidine kinase
AMK58_21155	COG0745	RESPONSE REGULATOR receiver
AMK58_21185	COG1028	Short-chain dehydrogenase reductase Sdr
AMK58_21195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AMK58_21220	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AMK58_21225	COG2864	formate dehydrogenase
AMK58_21230	COG0437	4 iron, 4 sulfur cluster binding
AMK58_21235	COG0243	molybdopterin cofactor binding
AMK58_21235	COG3383	formate dehydrogenase (NAD+) activity
AMK58_21275	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AMK58_21295	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AMK58_21305	COG3648	Uricase
AMK58_21305	COG3195	allantoin biosynthetic process
AMK58_21320	COG0583	DNA-binding transcription factor activity
AMK58_21325	COG1609	Transcriptional regulator
AMK58_21365	COG1032	radical SAM domain protein
AMK58_21375	COG0791	NLP P60 protein
AMK58_21380	COG1648	precorrin-2 dehydrogenase activity
AMK58_21380	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AMK58_21385	COG0243	molybdopterin cofactor binding
AMK58_21390	COG2146	nitrite reductase [NAD(P)H] activity
AMK58_21395	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AMK58_21400	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AMK58_21410	COG1116	anion transmembrane transporter activity
AMK58_21415	COG3707	response regulator
AMK58_21430	COG0251	oxidation-reduction process
AMK58_21435	COG0583	DNA-binding transcription factor activity
AMK58_21450	COG1475	DNA binding
AMK58_21455	COG1192	Involved in chromosome partitioning
AMK58_21465	COG3591	Belongs to the peptidase S1B family
AMK58_21475	COG0420	3'-5' exonuclease activity
AMK58_21515	COG1942	4-Oxalocrotonate Tautomerase
AMK58_21520	COG0235	Class ii aldolase
AMK58_21540	COG3383	formate dehydrogenase (NAD+) activity
AMK58_21540	COG0243	molybdopterin cofactor binding
AMK58_21545	COG0437	4 iron, 4 sulfur cluster binding
AMK58_21550	COG2864	formate dehydrogenase
AMK58_21555	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AMK58_21560	COG2205	protein histidine kinase activity
AMK58_21565	COG0745	RESPONSE REGULATOR receiver
AMK58_21580	COG0840	transmembrane signaling receptor activity
AMK58_21590	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AMK58_21600	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AMK58_21630	COG2027	D-alanyl-D-alanine carboxypeptidase
AMK58_21700	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AMK58_21705	COG0392	lysyltransferase activity
AMK58_21730	COG0406	alpha-ribazole phosphatase activity
AMK58_21730	COG0328	RNA-DNA hybrid ribonuclease activity
AMK58_21735	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AMK58_21745	COG0477	Major facilitator Superfamily
AMK58_21750	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AMK58_21755	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AMK58_21760	COG1845	cytochrome c oxidase, subunit III
AMK58_21795	COG3005	denitrification pathway
AMK58_21820	COG4459	periplasmic nitrate reductase
AMK58_21840	COG0670	Belongs to the BI1 family
AMK58_21865	COG2204	response regulator
AMK58_21870	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMK58_21880	COG1850	ribulose-bisphosphate carboxylase activity
AMK58_21890	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AMK58_21895	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AMK58_21910	COG3246	L-lysine catabolic process to acetate
AMK58_21915	COG0028	Belongs to the TPP enzyme family
AMK58_21935	COG4172	Belongs to the ABC transporter superfamily
AMK58_21940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AMK58_21955	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AMK58_21960	COG0583	DNA-binding transcription factor activity
AMK58_21985	COG0438	transferase activity, transferring glycosyl groups
AMK58_22005	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMK58_22030	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMK58_22035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMK58_22055	COG2197	response regulator
AMK58_22060	COG2197	response regulator
AMK58_22070	COG3387	PFAM Glycoside hydrolase 15-related
AMK58_22110	COG5002	protein histidine kinase activity
AMK58_22110	COG0784	Response regulator, receiver
AMK58_22115	COG0154	amidase activity
AMK58_22125	COG2351	hydroxyisourate hydrolase activity
AMK58_22135	COG1176	ABC-type spermidine putrescine transport system, permease component I
AMK58_22140	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AMK58_22145	COG3842	ATPase activity
AMK58_22165	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AMK58_22170	COG1116	anion transmembrane transporter activity
AMK58_22175	COG0402	S-adenosylhomocysteine deaminase activity
AMK58_22200	COG0840	transmembrane signaling receptor activity
AMK58_22205	COG0318	PFAM AMP-dependent synthetase and ligase
AMK58_22210	COG1176	ABC-type spermidine putrescine transport system, permease component I
AMK58_22215	COG3842	ATPase activity
AMK58_22225	COG1024	Enoyl-CoA hydratase
AMK58_22230	COG1414	Transcriptional regulator
AMK58_22315	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
AMK58_22325	COG0189	ligase activity
AMK58_22330	COG3252	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT
AMK58_22340	COG0702	epimerase
AMK58_22350	COG2154	pterin-4-alpha-carbinolamine dehydratase
AMK58_22360	COG1229	Formylmethanofuran dehydrogenase subunit A
AMK58_22365	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
AMK58_22385	COG1131	(ABC) transporter
AMK58_22445	COG2010	Cytochrome c
AMK58_22465	COG1573	uracil-dna glycosylase
AMK58_22480	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AMK58_22490	COG0583	DNA-binding transcription factor activity
AMK58_22515	COG1028	Short-chain dehydrogenase reductase Sdr
AMK58_22560	COG1764	response to oxidative stress
AMK58_22565	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AMK58_22570	COG1960	acyl-CoA dehydrogenase activity
AMK58_22575	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AMK58_22645	COG0668	transmembrane transport
AMK58_22685	COG1139	Iron-sulfur cluster binding protein
AMK58_22690	COG0247	lactate metabolic process
AMK58_22695	COG0277	FAD linked oxidase domain protein
AMK58_22700	COG1620	l-lactate permease
AMK58_22705	COG2186	Transcriptional regulator
AMK58_22715	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AMK58_22720	COG0542	response to heat
AMK58_22725	COG1414	Transcriptional regulator
AMK58_22730	COG3734	2-keto-3-deoxy-galactonokinase
AMK58_22735	COG0800	Aldolase
AMK58_22760	COG1028	Short-chain dehydrogenase reductase Sdr
AMK58_22780	COG2205	protein histidine kinase activity
AMK58_22780	COG0784	Response regulator, receiver
AMK58_22780	COG5002	protein histidine kinase activity
AMK58_22790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMK58_22825	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AMK58_22830	COG4191	Histidine kinase
AMK58_22835	COG4566	intracellular signal transduction
AMK58_22845	COG0848	biopolymer transport protein
AMK58_22885	COG3275	phosphorelay sensor kinase activity
AMK58_22895	COG1966	Carbon starvation protein
AMK58_22905	COG1363	Peptidase, m42
AMK58_22910	COG1181	Belongs to the D-alanine--D-alanine ligase family
AMK58_22910	COG2918	glutathione biosynthetic process
AMK58_22915	COG0367	asparagine synthase
AMK58_22955	COG1802	Transcriptional regulator
AMK58_22960	COG2239	Acts as a magnesium transporter
AMK58_22970	COG0861	Integral membrane protein TerC family
AMK58_23030	COG2226	methyltransferase
AMK58_23050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMK58_23060	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AMK58_23065	COG1846	Transcriptional regulator
AMK58_23075	COG1309	transcriptional regulator
AMK58_23080	COG0318	PFAM AMP-dependent synthetase and ligase
AMK58_23085	COG2186	Transcriptional regulator
AMK58_23090	COG1960	acyl-CoA dehydrogenase activity
AMK58_23100	COG2382	esterase
AMK58_23105	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AMK58_23115	COG1028	Short-chain dehydrogenase reductase Sdr
AMK58_23120	COG1535	isochorismatase
AMK58_23120	COG3433	isochorismatase activity
AMK58_23125	COG1021	2,3-dihydroxybenzoate-AMP ligase
AMK58_23130	COG1169	isochorismate synthase
AMK58_23150	COG4771	TonB-dependent receptor
AMK58_23170	COG2201	protein-glutamate methylesterase activity
AMK58_23180	COG0747	negative chemotaxis
AMK58_23185	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AMK58_23200	COG0559	Belongs to the binding-protein-dependent transport system permease family
AMK58_23220	COG0318	PFAM AMP-dependent synthetase and ligase
AMK58_23230	COG1960	acyl-CoA dehydrogenase activity
AMK58_23235	COG0183	Belongs to the thiolase family
AMK58_23240	COG1960	acyl-CoA dehydrogenase activity
AMK58_23245	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AMK58_23250	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AMK58_23285	COG2819	hydrolase of the alpha beta superfamily
AMK58_23305	COG2723	6-phospho-beta-galactosidase activity
AMK58_23310	COG2723	6-phospho-beta-galactosidase activity
AMK58_23320	COG4178	(ABC) transporter
AMK58_23330	COG1216	Glycosyl transferase, family 2
AMK58_23330	COG1442	glycosyl transferase family 8
AMK58_23350	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AMK58_23400	COG0739	heme binding
AMK58_23415	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AMK58_23425	COG0745	RESPONSE REGULATOR receiver
AMK58_23430	COG0642	Histidine kinase
AMK58_23445	COG1660	Displays ATPase and GTPase activities
AMK58_23450	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AMK58_23450	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMK58_23455	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMK58_23465	COG0583	DNA-binding transcription factor activity
AMK58_23475	COG0747	negative chemotaxis
AMK58_23495	COG0251	oxidation-reduction process
AMK58_23505	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AMK58_23520	COG3842	ATPase activity
AMK58_23535	COG2985	domain, Protein
AMK58_23545	COG2204	response regulator
AMK58_23575	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AMK58_23585	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AMK58_23600	COG2197	response regulator
AMK58_23610	COG2198	Histidine kinase
AMK58_23610	COG0643	Histidine kinase
AMK58_23615	COG0745	RESPONSE REGULATOR receiver
AMK58_23615	COG3706	GGDEF domain
AMK58_23620	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AMK58_23630	COG2201	protein-glutamate methylesterase activity
AMK58_23635	COG0835	chemotaxis
AMK58_23640	COG0840	transmembrane signaling receptor activity
AMK58_23655	COG2095	MarC family integral membrane protein
AMK58_23680	COG1028	Short-chain dehydrogenase reductase Sdr
AMK58_23685	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AMK58_23700	COG0395	ABC-type sugar transport system, permease component
AMK58_23710	COG3842	ATPase activity
AMK58_23725	COG0586	Pfam SNARE associated Golgi protein
AMK58_23745	COG4615	Cyclic peptide transporter
AMK58_23780	COG0840	transmembrane signaling receptor activity
AMK58_23800	COG0784	Response regulator, receiver
AMK58_23800	COG5002	protein histidine kinase activity
AMK58_23805	COG0784	Response regulator, receiver
AMK58_23805	COG4191	Histidine kinase
AMK58_23820	COG2388	GCN5-related N-acetyl-transferase
AMK58_23825	COG0366	Alpha amylase catalytic
AMK58_23830	COG1028	Short-chain dehydrogenase reductase Sdr
AMK58_23855	COG3290	protein histidine kinase activity
AMK58_23855	COG0840	transmembrane signaling receptor activity
AMK58_23860	COG1971	Probably functions as a manganese efflux pump
AMK58_23905	COG1473	amidohydrolase
AMK58_23910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMK58_23925	COG0559	Belongs to the binding-protein-dependent transport system permease family
AMK58_23935	COG0411	ABC transporter
AMK58_23950	COG0840	transmembrane signaling receptor activity
AMK58_23950	COG0840	transmembrane signaling receptor activity
AMK58_23970	COG3842	ATPase activity
AMK58_23985	COG1653	transport
AMK58_23995	COG1192	Involved in chromosome partitioning
AMK58_24025	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AMK58_24035	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AMK58_24040	COG0628	permease
AMK58_24050	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMK58_24055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMK58_24065	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AMK58_24150	COG0243	molybdopterin cofactor binding
AMK58_24175	COG0427	acetyl-CoA hydrolase
AMK58_24185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMK58_24190	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMK58_24195	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMK58_24200	COG1538	Outer membrane efflux protein
AMK58_24210	COG4191	Histidine kinase
AMK58_24215	COG4566	intracellular signal transduction
AMK58_24220	COG4566	intracellular signal transduction
AMK58_24235	COG2353	YceI-like domain
AMK58_24240	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMK58_24250	COG0861	Integral membrane protein TerC family
AMK58_24260	COG2205	protein histidine kinase activity
AMK58_24265	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AMK58_24270	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AMK58_24275	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AMK58_24285	COG1802	Transcriptional regulator
AMK58_24290	COG3180	Ammonia monooxygenase
AMK58_24295	COG1335	isochorismatase
AMK58_24300	COG4608	Belongs to the ABC transporter superfamily
AMK58_24320	COG0747	negative chemotaxis
AMK58_24325	COG1335	isochorismatase
AMK58_24330	COG0154	amidase activity
AMK58_24335	COG0154	amidase activity
AMK58_24340	COG3791	Glutathione-dependent formaldehyde-activating
AMK58_24345	COG0842	Transport permease protein
AMK58_24350	COG1131	(ABC) transporter
AMK58_24355	COG1418	mRNA catabolic process
AMK58_24375	COG2354	Protein conserved in bacteria
AMK58_24380	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AMK58_24390	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AMK58_24395	COG1802	Transcriptional regulator
AMK58_24400	COG0583	DNA-binding transcription factor activity
AMK58_24410	COG1522	sequence-specific DNA binding
AMK58_24420	COG1959	2 iron, 2 sulfur cluster binding
AMK58_24430	COG1994	Peptidase M50
AMK58_24430	COG0517	IMP dehydrogenase activity
AMK58_24450	COG1028	Short-chain dehydrogenase reductase Sdr
AMK58_24465	COG4566	intracellular signal transduction
AMK58_24475	COG0446	pyridine nucleotide-disulphide oxidoreductase
AMK58_24495	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AMK58_24500	COG0640	Transcriptional regulator
AMK58_24570	COG1216	Glycosyl transferase, family 2
AMK58_24600	COG0489	protein tyrosine kinase activity
AMK58_24600	COG3206	protein involved in exopolysaccharide biosynthesis
AMK58_24605	COG3307	-O-antigen
AMK58_24620	COG1215	transferase activity, transferring glycosyl groups
AMK58_24630	COG3622	Belongs to the hyi family
AMK58_24650	COG4783	chaperone-mediated protein folding
AMK58_24655	COG1192	Involved in chromosome partitioning
AMK58_24660	COG1475	DNA binding
AMK58_24670	COG4178	(ABC) transporter
AMK58_24675	COG0840	transmembrane signaling receptor activity
AMK58_24730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMK58_24760	COG0339	signal peptide processing
AMK58_24765	COG4175	Glycine betaine
AMK58_24770	COG4176	ABC-type proline glycine betaine transport system permease component
AMK58_24775	COG2113	Glycine betaine
AMK58_24795	COG1764	response to oxidative stress
AMK58_24800	COG1846	Transcriptional regulator
AMK58_24820	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AMK58_24825	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AMK58_24845	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AMK58_24920	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AMK58_24925	COG1028	Short-chain dehydrogenase reductase Sdr
AMK58_24940	COG1595	DNA-templated transcription, initiation
AMK58_25005	COG1132	(ABC) transporter
AMK58_25020	COG2199	diguanylate cyclase activity
AMK58_25020	COG2203	Gaf domain
AMK58_25040	COG0405	Gamma-glutamyltransferase
AMK58_25070	COG1858	cytochrome C peroxidase
AMK58_25090	COG4964	Belongs to the GSP D family
AMK58_25220	COG1012	belongs to the aldehyde dehydrogenase family
AMK58_25240	COG0668	transmembrane transport
AMK58_25255	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AMK58_25265	COG1338	Plays a role in the flagellum-specific transport system
AMK58_25270	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AMK58_25280	COG1766	The M ring may be actively involved in energy transduction
AMK58_25320	COG3005	denitrification pathway
AMK58_25330	COG0243	molybdopterin cofactor binding
AMK58_25350	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AMK58_25355	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
AMK58_25360	COG4786	Flagellar basal body rod
AMK58_25365	COG4786	Flagellar basal body rod
AMK58_25375	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AMK58_25380	COG1360	Flagellar Motor Protein
AMK58_25455	COG1454	alcohol dehydrogenase
AMK58_25455	COG1012	belongs to the aldehyde dehydrogenase family
AMK58_25515	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AMK58_25545	COG4221	oxidoreductase activity
AMK58_25560	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMK58_25565	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AMK58_25570	COG0583	DNA-binding transcription factor activity
AMK58_25575	COG0028	Belongs to the TPP enzyme family
AMK58_25580	COG1012	belongs to the aldehyde dehydrogenase family
AMK58_25605	COG0784	Response regulator, receiver
AMK58_25605	COG4191	Histidine kinase
AMK58_25610	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
AMK58_25645	COG2855	membrane
AMK58_25650	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AMK58_25650	COG2169	Transcriptional regulator
AMK58_25660	COG0546	phosphoglycolate phosphatase activity
AMK58_25680	COG1192	Involved in chromosome partitioning
AMK58_25685	COG1475	DNA binding
AMK58_25690	COG0028	Belongs to the TPP enzyme family
AMK58_25705	COG0437	4 iron, 4 sulfur cluster binding
AMK58_25710	COG0243	molybdopterin cofactor binding
AMK58_25715	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AMK58_25720	COG0045	succinate-CoA ligase (ADP-forming) activity
AMK58_25725	COG1012	belongs to the aldehyde dehydrogenase family
AMK58_25745	COG0280	phosphate acetyltransferase
AMK58_25750	COG1414	Transcriptional regulator
AMK58_25755	COG1414	Transcriptional regulator
AMK58_25760	COG1522	sequence-specific DNA binding
AMK58_25765	COG0251	oxidation-reduction process
AMK58_25770	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AMK58_25785	COG0559	Belongs to the binding-protein-dependent transport system permease family
AMK58_25795	COG0411	ABC transporter
AMK58_25815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMK58_25830	COG0583	DNA-binding transcription factor activity
AMK58_25860	COG2197	response regulator
AMK58_25865	COG3920	Histidine kinase
AMK58_25875	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AMK58_25875	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AMK58_25880	COG1105	Belongs to the carbohydrate kinase PfkB family
AMK58_25885	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AMK58_25885	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMK58_25890	COG1609	Transcriptional regulator
AMK58_25900	COG1335	isochorismatase
AMK58_25905	COG2309	aminopeptidase activity
AMK58_25910	COG0596	Alpha beta hydrolase
AMK58_25915	COG3473	Maleate cis-trans isomerase
AMK58_25940	COG0559	Belongs to the binding-protein-dependent transport system permease family
AMK58_25945	COG0683	leucine binding
AMK58_25960	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AMK58_25980	COG0559	Belongs to the binding-protein-dependent transport system permease family
AMK58_25990	COG0411	ABC transporter
AMK58_26020	COG0154	amidase activity
AMK58_26045	COG2086	electron transfer activity
AMK58_26050	COG0277	FAD linked oxidase domain protein
AMK58_26060	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AMK58_26075	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AMK58_26080	COG0567	Dehydrogenase, E1 component
AMK58_26100	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AMK58_26105	COG1845	cytochrome c oxidase, subunit III
AMK58_26115	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AMK58_26135	COG1120	ATPase activity
AMK58_26140	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AMK58_26145	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AMK58_26160	COG1802	Transcriptional regulator
AMK58_26165	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AMK58_26185	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AMK58_26195	COG5443	negative regulation of bacterial-type flagellum assembly
AMK58_26215	COG2814	Major facilitator Superfamily
AMK58_26230	COG1157	protein secretion by the type III secretion system
AMK58_26235	COG1815	bacterial-type flagellum-dependent cell motility
AMK58_26240	COG1558	bacterial-type flagellum-dependent cell motility
AMK58_26245	COG1677	Flagellar hook-basal body complex protein FliE
AMK58_26250	COG4794	Type iii secretion
AMK58_26260	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AMK58_26265	COG1684	flagellar biosynthetic protein fliR
AMK58_26270	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AMK58_26280	COG1522	sequence-specific DNA binding
AMK58_26290	COG0028	Belongs to the TPP enzyme family
AMK58_26300	COG4191	Histidine kinase
AMK58_26310	COG0793	Belongs to the peptidase S41A family
AMK58_26315	COG0583	DNA-binding transcription factor activity
AMK58_26320	COG1028	Short-chain dehydrogenase reductase Sdr
AMK58_26345	COG5001	Diguanylate cyclase
AMK58_26345	COG3300	MHYT domain
AMK58_26370	COG1706	bacterial-type flagellum-dependent cell motility
AMK58_26380	COG1256	bacterial-type flagellum assembly
AMK58_26385	COG1749	Flagellar hook protein flgE
AMK58_26410	COG0840	transmembrane signaling receptor activity
AMK58_26415	COG0861	Integral membrane protein TerC family
AMK58_26420	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AMK58_26430	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AMK58_26435	COG1802	Transcriptional regulator
AMK58_26440	COG0697	spore germination
AMK58_26445	COG2116	formate transmembrane transporter activity
AMK58_26450	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AMK58_26455	COG0469	pyruvate kinase activity
AMK58_26460	COG4251	negative regulation of phosphorylation
AMK58_26465	COG5002	protein histidine kinase activity
AMK58_26470	COG1309	transcriptional regulator
AMK58_26475	COG1309	transcriptional regulator
AMK58_26480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMK58_26485	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMK58_26490	COG1737	Transcriptional regulator
AMK58_26490	COG0837	glucose binding
AMK58_26495	COG1882	Formate acetyltransferase
AMK58_26500	COG0148	phosphopyruvate hydratase activity
AMK58_26510	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AMK58_26520	COG1028	Short-chain dehydrogenase reductase Sdr
AMK58_26525	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
AMK58_26530	COG1802	Transcriptional regulator
AMK58_26575	COG3416	Protein conserved in bacteria
AMK58_26580	COG0628	permease
AMK58_26590	COG1597	lipid kinase activity
AMK58_26610	COG3383	formate dehydrogenase (NAD+) activity
AMK58_26615	COG1414	Transcriptional regulator
AMK58_26640	COG4191	Histidine kinase
AMK58_26645	COG0840	transmembrane signaling receptor activity
AMK58_26650	COG0402	S-adenosylhomocysteine deaminase activity
AMK58_26660	COG4603	Belongs to the binding-protein-dependent transport system permease family
AMK58_26675	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AMK58_26700	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AMK58_26790	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AMK58_26790	COG2226	methyltransferase
AMK58_26790	COG0596	Alpha beta hydrolase
AMK58_26795	COG0183	Belongs to the thiolase family
AMK58_26800	COG1028	Short-chain dehydrogenase reductase Sdr
AMK58_26810	COG2814	Major facilitator Superfamily
AMK58_26815	COG0583	DNA-binding transcription factor activity
AMK58_26825	COG3300	MHYT domain
AMK58_26825	COG5001	Diguanylate cyclase
AMK58_26830	COG0012	GTP binding
AMK58_26850	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AMK58_26850	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AMK58_26875	COG1131	(ABC) transporter
AMK58_26920	COG1254	Belongs to the acylphosphatase family
AMK58_26925	COG2233	PERMEase
AMK58_26930	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AMK58_26935	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AMK58_26945	COG1178	ABC-type Fe3 transport system permease component
AMK58_26950	COG1176	ABC-type spermidine putrescine transport system, permease component I
AMK58_26955	COG3842	ATPase activity
AMK58_26980	COG1045	serine acetyltransferase
AMK58_26995	COG4191	Histidine kinase
AMK58_27020	COG0784	Response regulator, receiver
AMK58_27025	COG4251	negative regulation of phosphorylation
AMK58_27050	COG0191	fructose-bisphosphate aldolase activity
AMK58_27060	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AMK58_27065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMK58_27120	COG2022	thiamine diphosphate biosynthetic process
AMK58_27130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMK58_27130	COG2022	thiamine diphosphate biosynthetic process
AMK58_27135	COG2239	Acts as a magnesium transporter
AMK58_27165	COG0747	negative chemotaxis
AMK58_27170	COG0601	transmembrane transport
AMK58_27180	COG0444	Belongs to the ABC transporter superfamily
AMK58_27185	COG4608	Belongs to the ABC transporter superfamily
AMK58_27190	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AMK58_27200	COG1028	Short-chain dehydrogenase reductase Sdr
AMK58_27240	COG0484	heat shock protein binding
AMK58_27250	COG0564	pseudouridine synthase activity
AMK58_27265	COG0156	8-amino-7-oxononanoate synthase activity
AMK58_27275	COG4106	trans-aconitate 2-methyltransferase activity
AMK58_27275	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AMK58_27285	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AMK58_27295	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AMK58_27295	COG0574	Belongs to the PEP-utilizing enzyme family
AMK58_27305	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AMK58_27310	COG1278	Cold shock
AMK58_27315	COG0318	PFAM AMP-dependent synthetase and ligase
AMK58_27345	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AMK58_27350	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AMK58_27360	COG1172	Belongs to the binding-protein-dependent transport system permease family
AMK58_27365	COG1172	Belongs to the binding-protein-dependent transport system permease family
AMK58_27370	COG1129	ABC transporter
AMK58_27375	COG1879	ABC-type sugar transport system periplasmic component
AMK58_27410	COG4214	carbohydrate transport
AMK58_27420	COG0129	dihydroxy-acid dehydratase activity
AMK58_27435	COG0246	Mannitol dehydrogenase
AMK58_27440	COG0725	ABC transporter, periplasmic molybdate-binding protein
AMK58_27455	COG5039	Polysaccharide pyruvyl transferase
AMK58_27460	COG2132	Multicopper oxidase
AMK58_27470	COG1309	transcriptional regulator
AMK58_27475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMK58_27480	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMK58_27485	COG0702	epimerase
AMK58_27490	COG1733	regulation of RNA biosynthetic process
AMK58_27500	COG0583	DNA-binding transcription factor activity
AMK58_27515	COG2133	pyrroloquinoline quinone binding
AMK58_27550	COG1312	Catalyzes the dehydration of D-mannonate
AMK58_27555	COG0246	Mannitol dehydrogenase
AMK58_27570	COG1802	Transcriptional regulator
AMK58_27575	COG1028	Short-chain dehydrogenase reductase Sdr
AMK58_27580	COG1917	Cupin 2, conserved barrel domain protein
AMK58_27585	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AMK58_27595	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AMK58_27615	COG4774	siderophore transport
AMK58_27620	COG0667	Aldo Keto reductase
AMK58_27625	COG1802	Transcriptional regulator
AMK58_27630	COG1803	Methylglyoxal synthase
AMK58_27635	COG1904	glucuronate isomerase
AMK58_27640	COG2721	sulfolactate sulfo-lyase activity
AMK58_27675	COG0861	Integral membrane protein TerC family
AMK58_27725	COG2188	Transcriptional regulator
AMK58_27740	COG0154	amidase activity
AMK58_27755	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AMK58_27760	COG1960	acyl-CoA dehydrogenase activity
AMK58_27765	COG2079	MmgE PrpD family protein
AMK58_27785	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AMK58_27790	COG1028	Short-chain dehydrogenase reductase Sdr
AMK58_27825	COG0714	Associated with various cellular activities
AMK58_27865	COG0626	cystathionine gamma-synthase activity
AMK58_27875	COG1429	ligase activity, forming nitrogen-metal bonds
AMK58_27895	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AMK58_27900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMK58_27905	COG3411	Ferredoxin
AMK58_27910	COG4774	siderophore transport
AMK58_27915	COG0864	Transcriptional regulator
AMK58_27920	COG0747	negative chemotaxis
AMK58_27990	COG1959	2 iron, 2 sulfur cluster binding
AMK58_28010	COG1024	Enoyl-CoA hydratase
AMK58_28015	COG1028	Short-chain dehydrogenase reductase Sdr
AMK58_28020	COG0183	Belongs to the thiolase family
AMK58_28030	COG1028	Short-chain dehydrogenase reductase Sdr
AMK58_28035	COG0583	DNA-binding transcription factor activity
AMK58_28040	COG0477	Major facilitator Superfamily
AMK58_28050	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AMK58_28055	COG1012	belongs to the aldehyde dehydrogenase family
AMK58_28065	COG0583	DNA-binding transcription factor activity
AMK58_28085	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AMK58_28095	COG2010	Cytochrome c
AMK58_28095	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AMK58_28140	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AMK58_28220	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMK58_28220	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AMK58_28225	COG0673	inositol 2-dehydrogenase activity
AMK58_28245	COG0793	Belongs to the peptidase S41A family
AMK58_28275	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AMK58_28280	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AMK58_28285	COG2885	chlorophyll binding
AMK58_28290	COG0517	IMP dehydrogenase activity
AMK58_28295	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AMK58_28320	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AMK58_28335	COG4584	PFAM Integrase catalytic
AMK58_28340	COG1484	DNA-dependent DNA replication
AMK58_28425	COG0745	RESPONSE REGULATOR receiver
AMK58_28430	COG2205	protein histidine kinase activity
AMK58_28435	COG1132	(ABC) transporter
AMK58_28440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMK58_28475	COG2010	Cytochrome c
AMK58_28485	COG3794	PFAM blue (type 1) copper domain protein
AMK58_28515	COG0672	)-iron permease
AMK58_28545	COG0181	hydroxymethylbilane synthase activity
AMK58_28555	COG0535	radical SAM domain protein
AMK58_28585	COG2010	Cytochrome c
AMK58_28590	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AMK58_28590	COG1648	precorrin-2 dehydrogenase activity
AMK58_28605	COG0840	transmembrane signaling receptor activity
AMK58_28610	COG3316	Transposase and inactivated derivatives
AMK58_28615	COG0156	8-amino-7-oxononanoate synthase activity
AMK58_28635	COG3256	nitric oxide reductase
AMK58_28650	COG0045	succinate-CoA ligase (ADP-forming) activity
AMK58_28650	COG1042	CoA-binding domain protein
AMK58_28650	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AMK58_28655	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AMK58_28665	COG0784	Response regulator, receiver
AMK58_28665	COG2205	protein histidine kinase activity
AMK58_28670	COG2205	protein histidine kinase activity
AMK58_28700	COG0714	Associated with various cellular activities
AMK58_28725	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AMK58_28745	COG0438	transferase activity, transferring glycosyl groups
AMK58_28755	COG0438	transferase activity, transferring glycosyl groups
AMK58_28755	COG1216	Glycosyl transferase, family 2
AMK58_28765	COG0438	transferase activity, transferring glycosyl groups
AMK58_28805	COG0463	Glycosyl transferase, family 2
AMK58_28815	COG1215	transferase activity, transferring glycosyl groups
AMK58_28820	COG0438	transferase activity, transferring glycosyl groups
AMK58_28890	COG0438	transferase activity, transferring glycosyl groups
AMK58_28895	COG0500	methyltransferase
AMK58_28900	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AMK58_28905	COG0579	oxidoreductase
AMK58_28915	COG0297	glycogen (starch) synthase activity
AMK58_28920	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AMK58_28925	COG1088	dTDP-glucose 4,6-dehydratase activity
AMK58_28945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMK58_28960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMK58_28980	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AMK58_28990	COG3754	Rhamnan synthesis protein F
AMK58_29035	COG0297	glycogen (starch) synthase activity
AMK58_29045	COG1216	Glycosyl transferase, family 2
AMK58_29085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMK58_29095	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AMK58_29125	COG1192	Involved in chromosome partitioning
AMK58_29130	COG1475	DNA binding
AMK58_29140	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AMK58_29155	COG1086	Polysaccharide biosynthesis protein
AMK58_29165	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AMK58_29180	COG1051	belongs to the nudix hydrolase family
AMK58_29200	COG0528	UMP kinase activity
AMK58_29205	COG0528	UMP kinase activity
AMK58_29230	COG1088	dTDP-glucose 4,6-dehydratase activity
AMK58_29250	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AMK58_29260	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AMK58_29280	COG0438	transferase activity, transferring glycosyl groups
AMK58_29290	COG1216	Glycosyl transferase, family 2
AMK58_29290	COG0438	transferase activity, transferring glycosyl groups