locus-tag	class	description
AZOLI_0002	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AZOLI_0003	COG3706	GGDEF domain
AZOLI_0005	COG0745	RESPONSE REGULATOR receiver
AZOLI_0008	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AZOLI_0010	COG3842	ATPase activity
AZOLI_0011	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AZOLI_0012	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AZOLI_0024	COG2264	protein methyltransferase activity
AZOLI_0028	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AZOLI_0053	COG1234	tRNA 3'-trailer cleavage
AZOLI_0055	COG0745	RESPONSE REGULATOR receiver
AZOLI_0060	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AZOLI_0074	COG1509	lysine 2,3-aminomutase activity
AZOLI_0075	COG0584	glycerophosphoryl diester phosphodiesterase
AZOLI_0081	COG2205	protein histidine kinase activity
AZOLI_0081	COG2202	Pas domain
AZOLI_0084	COG3162	membrane
AZOLI_0087	COG0318	PFAM AMP-dependent synthetase and ligase
AZOLI_0090	COG1960	acyl-CoA dehydrogenase activity
AZOLI_0091	COG1187	pseudouridine synthase activity
AZOLI_0095	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AZOLI_0097	COG4974	Belongs to the 'phage' integrase family
AZOLI_0106	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AZOLI_0107	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AZOLI_0108	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AZOLI_0112	COG3437	response regulator, receiver
AZOLI_0112	COG0784	Response regulator, receiver
AZOLI_0114	COG0583	DNA-binding transcription factor activity
AZOLI_0116	COG0252	asparaginase activity
AZOLI_0121	COG0297	glycogen (starch) synthase activity
AZOLI_0122	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AZOLI_0124	COG0004	ammonium transporteR
AZOLI_0125	COG1741	Belongs to the pirin family
AZOLI_0131	COG2313	pseudouridylate synthase activity
AZOLI_0133	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AZOLI_0133	COG1793	dna ligase
AZOLI_0136	COG3660	Nucleoside-diphosphate-sugar epimerase
AZOLI_0137	COG1522	sequence-specific DNA binding
AZOLI_0138	COG2059	Chromate
AZOLI_0140	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AZOLI_0141	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AZOLI_0144	COG3005	denitrification pathway
AZOLI_0150	COG2205	protein histidine kinase activity
AZOLI_0152	COG2205	protein histidine kinase activity
AZOLI_0154	COG2318	DinB family
AZOLI_0155	COG1674	ftsk spoiiie
AZOLI_0159	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AZOLI_0160	COG1238	metal cluster binding
AZOLI_0162	COG2755	lipolytic protein G-D-S-L family
AZOLI_0162	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AZOLI_0174	COG0539	negative regulation of cytoplasmic translation
AZOLI_0178	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AZOLI_0181	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AZOLI_0181	COG0574	Belongs to the PEP-utilizing enzyme family
AZOLI_0182	COG1396	sequence-specific DNA binding
AZOLI_0192	COG1643	Atp-dependent helicase
AZOLI_0196	COG1366	Belongs to the anti-sigma-factor antagonist family
AZOLI_0202	COG4191	Histidine kinase
AZOLI_0206	COG0045	succinate-CoA ligase (ADP-forming) activity
AZOLI_0207	COG0039	L-malate dehydrogenase activity
AZOLI_0212	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
AZOLI_0214	COG0640	Transcriptional regulator
AZOLI_0217	COG1970	mechanosensitive ion channel activity
AZOLI_0218	COG0653	protein targeting
AZOLI_0219	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AZOLI_0220	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AZOLI_0221	COG0494	nUDIX hydrolase
AZOLI_0222	COG0514	ATP-dependent DNA helicase (RecQ)
AZOLI_0227	COG0024	Methionine aminopeptidase
AZOLI_0229	COG1489	DNA binding
AZOLI_0230	COG1546	Belongs to the CinA family
AZOLI_0230	COG1058	Belongs to the CinA family
AZOLI_0233	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AZOLI_0234	COG0640	Transcriptional regulator
AZOLI_0235	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AZOLI_0236	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
AZOLI_0237	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AZOLI_0238	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AZOLI_0241	COG1842	Phage shock protein A
AZOLI_0247	COG1216	Glycosyl transferase, family 2
AZOLI_0247	COG1442	glycosyl transferase family 8
AZOLI_0255	COG0181	hydroxymethylbilane synthase activity
AZOLI_0257	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AZOLI_0262	COG0587	DNA-directed DNA polymerase activity
AZOLI_0265	COG3437	response regulator, receiver
AZOLI_0265	COG0784	Response regulator, receiver
AZOLI_0266	COG3158	transport of potassium into the cell
AZOLI_0271	COG3609	addiction module antidote protein, CC2985 family
AZOLI_0272	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AZOLI_0274	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AZOLI_0275	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AZOLI_0276	COG0842	Transport permease protein
AZOLI_0277	COG2137	regulation of response to DNA damage stimulus
AZOLI_0279	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AZOLI_0281	COG1703	isobutyryl-CoA mutase activity
AZOLI_0282	COG4172	Belongs to the ABC transporter superfamily
AZOLI_0283	COG4239	(ABC) transporter, permease
AZOLI_0284	COG4174	ABC transporter (Permease)
AZOLI_0285	COG4166	transmembrane transport
AZOLI_0286	COG4166	transmembrane transport
AZOLI_0295	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AZOLI_0296	COG3474	cytochrome
AZOLI_0299	COG2766	serine protein kinase
AZOLI_0301	COG2718	Belongs to the UPF0229 family
AZOLI_0303	COG2719	SpoVR family
AZOLI_0308	COG0318	PFAM AMP-dependent synthetase and ligase
AZOLI_0309	COG1254	Belongs to the acylphosphatase family
AZOLI_0315	COG2239	Acts as a magnesium transporter
AZOLI_0318	COG2022	thiamine diphosphate biosynthetic process
AZOLI_0320	COG2022	thiamine diphosphate biosynthetic process
AZOLI_0320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZOLI_0321	COG0840	transmembrane signaling receptor activity
AZOLI_0340	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AZOLI_0341	COG3108	Peptidase M15
AZOLI_0342	COG2003	Belongs to the UPF0758 family
AZOLI_0344	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AZOLI_0345	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AZOLI_0348	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AZOLI_0349	COG0277	FAD linked oxidase domain protein
AZOLI_0350	COG0277	FAD linked oxidase domain protein
AZOLI_0351	COG0247	lactate metabolic process
AZOLI_0355	COG1454	alcohol dehydrogenase
AZOLI_0357	COG1960	acyl-CoA dehydrogenase activity
AZOLI_0361	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AZOLI_0362	COG2171	N-acyltransferase activity
AZOLI_0370	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AZOLI_0371	COG0228	four-way junction DNA binding
AZOLI_0372	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AZOLI_0373	COG0336	Belongs to the RNA methyltransferase TrmD family
AZOLI_0374	COG0335	large ribosomal subunit rRNA binding
AZOLI_0375	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AZOLI_0377	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AZOLI_0378	COG0706	membrane insertase activity
AZOLI_0379	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AZOLI_0381	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AZOLI_0383	COG0598	Magnesium transport protein CorA
AZOLI_0384	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AZOLI_0386	COG1530	ribonuclease E activity
AZOLI_0395	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AZOLI_0395	COG0561	phosphatase activity
AZOLI_0405	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AZOLI_0406	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZOLI_0407	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZOLI_0414	COG0411	ABC transporter
AZOLI_0434	COG3293	Transposase
AZOLI_0439	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AZOLI_0445	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AZOLI_0446	COG0081	regulation of translation
AZOLI_0448	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AZOLI_0450	COG0085	RNA polymerase activity
AZOLI_0451	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AZOLI_0456	COG0049	tRNA binding
AZOLI_0458	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AZOLI_0460	COG0051	transcription antitermination factor activity, RNA binding
AZOLI_0462	COG0088	Forms part of the polypeptide exit tunnel
AZOLI_0463	COG0089	rRNA binding
AZOLI_0464	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AZOLI_0465	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AZOLI_0466	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AZOLI_0467	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AZOLI_0468	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AZOLI_0469	COG0255	Belongs to the universal ribosomal protein uL29 family
AZOLI_0470	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AZOLI_0472	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AZOLI_0474	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AZOLI_0475	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AZOLI_0476	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AZOLI_0478	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AZOLI_0479	COG1841	ribosomal large subunit assembly
AZOLI_0480	COG0200	Binds to the 23S rRNA
AZOLI_0481	COG0201	protein transport
AZOLI_0482	COG0563	adenylate kinase activity
AZOLI_0484	COG0697	spore germination
AZOLI_0487	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AZOLI_0489	COG1073	alpha beta
AZOLI_0489	COG2226	methyltransferase
AZOLI_0491	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AZOLI_0504	COG1285	pathogenesis
AZOLI_0505	COG2814	Major facilitator Superfamily
AZOLI_0507	COG0196	riboflavin kinase activity
AZOLI_0508	COG2030	dehydratase
AZOLI_0509	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AZOLI_0512	COG0628	permease
AZOLI_0519	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AZOLI_0520	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AZOLI_0522	COG1597	lipid kinase activity
AZOLI_0524	COG0438	transferase activity, transferring glycosyl groups
AZOLI_0526	COG1280	lysine exporter protein (LysE YggA)
AZOLI_0529	COG1519	Transferase
AZOLI_0530	COG1663	tetraacyldisaccharide 4'-kinase activity
AZOLI_0536	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AZOLI_0537	COG0644	oxidoreductase
AZOLI_0549	COG1902	pentaerythritol trinitrate reductase activity
AZOLI_0551	COG2962	Rard protein
AZOLI_0554	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AZOLI_0557	COG5002	protein histidine kinase activity
AZOLI_0561	COG0395	ABC-type sugar transport system, permease component
AZOLI_0563	COG5508	conserved small protein
AZOLI_0564	COG0501	Belongs to the peptidase M48B family
AZOLI_0579	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AZOLI_0585	COG3293	Transposase
AZOLI_0591	COG1686	Belongs to the peptidase S11 family
AZOLI_0595	COG2205	protein histidine kinase activity
AZOLI_0595	COG2202	Pas domain
AZOLI_0596	COG5002	protein histidine kinase activity
AZOLI_0597	COG2205	protein histidine kinase activity
AZOLI_0599	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AZOLI_0602	COG0166	Belongs to the GPI family
AZOLI_0605	COG0612	Peptidase, M16
AZOLI_0606	COG0612	Peptidase, M16
AZOLI_0608	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AZOLI_0609	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AZOLI_0615	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AZOLI_0617	COG0840	transmembrane signaling receptor activity
AZOLI_0617	COG0840	transmembrane signaling receptor activity
AZOLI_0619	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AZOLI_0622	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AZOLI_0623	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AZOLI_0625	COG3609	addiction module antidote protein, CC2985 family
AZOLI_0628	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AZOLI_0629	COG0746	molybdenum cofactor guanylyltransferase activity
AZOLI_0634	COG3383	formate dehydrogenase (NAD+) activity
AZOLI_0634	COG0243	molybdopterin cofactor binding
AZOLI_0635	COG0437	4 iron, 4 sulfur cluster binding
AZOLI_0638	COG0235	Class ii aldolase
AZOLI_0639	COG2205	protein histidine kinase activity
AZOLI_0639	COG2202	Pas domain
AZOLI_0640	COG3384	dioxygenase
AZOLI_0641	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AZOLI_0642	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AZOLI_0643	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AZOLI_0644	COG0356	it plays a direct role in the translocation of protons across the membrane
AZOLI_0647	COG1999	signal sequence binding
AZOLI_0648	COG0840	transmembrane signaling receptor activity
AZOLI_0649	COG1702	phosphate starvation-inducible protein PhoH
AZOLI_0652	COG0850	regulation of cytokinetic process
AZOLI_0653	COG2894	cell division
AZOLI_0654	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AZOLI_0659	COG4948	Mandelate Racemase Muconate Lactonizing
AZOLI_0661	COG1573	uracil-dna glycosylase
AZOLI_0664	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AZOLI_0666	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AZOLI_0669	COG4231	catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
AZOLI_0670	COG5420	small protein containing a coiled-coil domain
AZOLI_0673	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AZOLI_0674	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AZOLI_0687	COG0121	glutamine amidotransferase
AZOLI_0689	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AZOLI_0690	COG0552	protein localization to endoplasmic reticulum
AZOLI_0691	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AZOLI_0694	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AZOLI_0704	COG2301	Belongs to the HpcH HpaI aldolase family
AZOLI_0705	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AZOLI_0706	COG2205	protein histidine kinase activity
AZOLI_0707	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AZOLI_0728	COG0582	viral genome integration into host DNA
AZOLI_0730	COG2972	Histidine kinase
AZOLI_0730	COG0840	transmembrane signaling receptor activity
AZOLI_0731	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AZOLI_0732	COG1063	alcohol dehydrogenase
AZOLI_0734	COG0596	Alpha beta hydrolase
AZOLI_0734	COG0508	dehydrogenase complex catalyzes the overall conversion of
AZOLI_0735	COG0022	dehydrogenase e1 component
AZOLI_0736	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AZOLI_0737	COG3199	ATP-NAD kinase
AZOLI_0739	COG0277	FAD linked oxidase domain protein
AZOLI_0744	COG1671	Belongs to the UPF0178 family
AZOLI_0746	COG0488	(ABC) transporter
AZOLI_0753	COG2853	Lipoprotein
AZOLI_0755	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AZOLI_0758	COG1410	methionine synthase
AZOLI_0758	COG0646	methionine synthase
AZOLI_0766	COG2814	Major facilitator Superfamily
AZOLI_0768	COG2944	sequence-specific DNA binding
AZOLI_0770	COG0175	sulfate reduction
AZOLI_0771	COG0175	sulfate reduction
AZOLI_0773	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AZOLI_0773	COG1648	precorrin-2 dehydrogenase activity
AZOLI_0775	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AZOLI_0779	COG3108	Peptidase M15
AZOLI_0782	COG2205	protein histidine kinase activity
AZOLI_0782	COG2202	Pas domain
AZOLI_0783	COG4566	intracellular signal transduction
AZOLI_0788	COG0243	molybdopterin cofactor binding
AZOLI_0789	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AZOLI_0789	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AZOLI_0791	COG3657	addiction module killer protein
AZOLI_0792	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AZOLI_0793	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AZOLI_0794	COG0840	transmembrane signaling receptor activity
AZOLI_0797	COG0612	Peptidase, M16
AZOLI_0798	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AZOLI_0802	COG0483	inositol monophosphate 1-phosphatase activity
AZOLI_0803	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AZOLI_0808	COG0730	response to heat
AZOLI_0809	COG0352	thiamine-phosphate diphosphorylase activity
AZOLI_0810	COG1830	Aldolase
AZOLI_0814	COG0840	transmembrane signaling receptor activity
AZOLI_0822	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AZOLI_0823	COG1692	metallophosphoesterase
AZOLI_0824	COG0217	transcriptional regulatory protein
AZOLI_0826	COG0632	four-way junction helicase activity
AZOLI_0827	COG2255	four-way junction helicase activity
AZOLI_0828	COG0824	Thioesterase
AZOLI_0830	COG0848	biopolymer transport protein
AZOLI_0836	COG0037	tRNA processing
AZOLI_0837	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AZOLI_0839	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AZOLI_0840	COG1295	ribonuclease BN
AZOLI_0841	COG3152	Membrane
AZOLI_0845	COG0259	pyridoxamine-phosphate oxidase activity
AZOLI_0848	COG1234	tRNA 3'-trailer cleavage
AZOLI_0849	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AZOLI_0850	COG2770	Histidine kinase
AZOLI_0850	COG3437	response regulator, receiver
AZOLI_0851	COG0409	Hydrogenase expression formation protein
AZOLI_0853	COG2153	protein acetylation
AZOLI_0856	COG3685	Protein conserved in bacteria
AZOLI_0859	COG4957	zinc ion binding
AZOLI_0861	COG0698	ribose 5-phosphate isomerase
AZOLI_0862	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AZOLI_0863	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AZOLI_0864	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AZOLI_0867	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AZOLI_0868	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AZOLI_0869	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AZOLI_0870	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AZOLI_0870	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AZOLI_0872	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AZOLI_0872	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AZOLI_0876	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AZOLI_0877	COG0416	fatty acid biosynthetic process
AZOLI_0878	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AZOLI_0890	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AZOLI_0893	COG4372	Transposase
AZOLI_0898	COG4608	Belongs to the ABC transporter superfamily
AZOLI_0899	COG0444	Belongs to the ABC transporter superfamily
AZOLI_0902	COG0747	negative chemotaxis
AZOLI_0903	COG0583	DNA-binding transcription factor activity
AZOLI_0910	COG1028	Short-chain dehydrogenase reductase Sdr
AZOLI_0913	COG0583	DNA-binding transcription factor activity
AZOLI_0915	COG1028	Short-chain dehydrogenase reductase Sdr
AZOLI_0918	COG1764	response to oxidative stress
AZOLI_0919	COG1846	Transcriptional regulator
AZOLI_0920	COG0456	acetyltransferase
AZOLI_0922	COG2890	protein-(glutamine-N5) methyltransferase activity
AZOLI_0923	COG1393	Belongs to the ArsC family
AZOLI_0924	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AZOLI_0926	COG1403	HNH endonuclease
AZOLI_0927	COG0697	spore germination
AZOLI_0932	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AZOLI_0936	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZOLI_0944	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AZOLI_0953	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AZOLI_0960	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AZOLI_0963	COG3108	Peptidase M15
AZOLI_0964	COG1396	sequence-specific DNA binding
AZOLI_0968	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AZOLI_0969	COG0511	ligase activity, forming carbon-carbon bonds
AZOLI_0970	COG0439	Biotin carboxylase
AZOLI_0972	COG0840	transmembrane signaling receptor activity
AZOLI_0973	COG4251	negative regulation of phosphorylation
AZOLI_0974	COG4251	negative regulation of phosphorylation
AZOLI_0975	COG0784	Response regulator, receiver
AZOLI_0976	COG3706	GGDEF domain
AZOLI_0976	COG0745	RESPONSE REGULATOR receiver
AZOLI_0978	COG0745	RESPONSE REGULATOR receiver
AZOLI_0982	COG0432	Pfam Uncharacterised protein family UPF0047
AZOLI_0984	COG0745	RESPONSE REGULATOR receiver
AZOLI_0986	COG2205	protein histidine kinase activity
AZOLI_0987	COG0628	permease
AZOLI_0990	COG0105	UTP biosynthetic process
AZOLI_0993	COG0745	RESPONSE REGULATOR receiver
AZOLI_0998	COG0515	serine threonine protein kinase
AZOLI_0998	COG2815	serine threonine protein kinase
AZOLI_1003	COG0500	methyltransferase
AZOLI_1018	COG3501	Rhs element vgr protein
AZOLI_1028	COG2208	phosphoserine phosphatase activity
AZOLI_1028	COG2770	Histidine kinase
AZOLI_1029	COG1366	Belongs to the anti-sigma-factor antagonist family
AZOLI_1034	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AZOLI_1036	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AZOLI_1037	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AZOLI_1039	COG3237	CsbD-like
AZOLI_1042	COG1742	UPF0060 membrane protein
AZOLI_1046	COG5001	Diguanylate cyclase
AZOLI_1047	COG1840	ABC-type Fe3 transport system, periplasmic component
AZOLI_1048	COG3842	ATPase activity
AZOLI_1049	COG1132	(ABC) transporter
AZOLI_1050	COG1752	Esterase of the alpha-beta hydrolase superfamily
AZOLI_1054	COG1178	ABC-type Fe3 transport system permease component
AZOLI_1061	COG0840	transmembrane signaling receptor activity
AZOLI_1064	COG1561	YicC-like family, N-terminal region
AZOLI_1065	COG4221	oxidoreductase activity
AZOLI_1068	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AZOLI_1069	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AZOLI_1070	COG0052	Belongs to the universal ribosomal protein uS2 family
AZOLI_1071	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AZOLI_1072	COG0528	UMP kinase activity
AZOLI_1073	COG0233	cytoplasmic translational termination
AZOLI_1074	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AZOLI_1075	COG0575	Belongs to the CDS family
AZOLI_1076	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AZOLI_1077	COG0750	zinc metalloprotease
AZOLI_1081	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AZOLI_1082	COG3494	Protein of unknown function (DUF1009)
AZOLI_1083	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AZOLI_1085	COG4977	sequence-specific DNA binding
AZOLI_1089	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AZOLI_1090	COG2333	competence protein COMEC
AZOLI_1090	COG0658	competence protein
AZOLI_1091	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AZOLI_1092	COG0303	'Molybdopterin
AZOLI_1093	COG0315	cyclic pyranopterin monophosphate synthase activity
AZOLI_1102	COG0739	heme binding
AZOLI_1102	COG0741	lytic transglycosylase activity
AZOLI_1102	COG1196	nuclear chromosome segregation
AZOLI_1103	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AZOLI_1104	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AZOLI_1105	COG2813	Specifically methylates the guanine in position
AZOLI_1106	COG0667	Aldo Keto reductase
AZOLI_1109	COG1881	PFAM PEBP family protein
AZOLI_1110	COG0113	porphobilinogen synthase activity
AZOLI_1112	COG1597	lipid kinase activity
AZOLI_1115	COG1024	Enoyl-CoA hydratase
AZOLI_1116	COG1846	Transcriptional regulator
AZOLI_1120	COG0559	Belongs to the binding-protein-dependent transport system permease family
AZOLI_1123	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AZOLI_1130	COG1028	Short-chain dehydrogenase reductase Sdr
AZOLI_1134	COG0058	SHG alpha-glucan phosphorylase activity
AZOLI_1135	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AZOLI_1137	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AZOLI_1138	COG3852	Histidine kinase
AZOLI_1140	COG1305	Transglutaminase-like
AZOLI_1141	COG2308	Evidence 4 Homologs of previously reported genes of
AZOLI_1141	COG2307	Protein conserved in bacteria
AZOLI_1142	COG2010	Cytochrome c
AZOLI_1146	COG1028	Short-chain dehydrogenase reductase Sdr
AZOLI_1147	COG0583	DNA-binding transcription factor activity
AZOLI_1151	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AZOLI_1161	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AZOLI_1162	COG2814	Major facilitator Superfamily
AZOLI_1166	COG1160	GTP binding
AZOLI_1173	COG1121	(ABC) transporter
AZOLI_1176	COG1136	(ABC) transporter
AZOLI_1176	COG0577	efflux transmembrane transporter activity
AZOLI_1177	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZOLI_1180	COG1595	DNA-templated transcription, initiation
AZOLI_1183	COG0024	Methionine aminopeptidase
AZOLI_1187	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AZOLI_1188	COG4221	oxidoreductase activity
AZOLI_1190	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AZOLI_1191	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AZOLI_1193	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AZOLI_1194	COG0628	permease
AZOLI_1196	COG0300	oxidoreductase activity
AZOLI_1197	COG1846	Transcriptional regulator
AZOLI_1207	COG1396	sequence-specific DNA binding
AZOLI_1208	COG1216	Glycosyl transferase, family 2
AZOLI_1218	COG2205	protein histidine kinase activity
AZOLI_1219	COG0745	RESPONSE REGULATOR receiver
AZOLI_1221	COG1846	Transcriptional regulator
AZOLI_1222	COG0149	triose-phosphate isomerase activity
AZOLI_1226	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AZOLI_1228	COG1566	PFAM secretion protein HlyD family protein
AZOLI_1229	COG1136	(ABC) transporter
AZOLI_1230	COG1136	(ABC) transporter
AZOLI_1230	COG0577	efflux transmembrane transporter activity
AZOLI_1234	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AZOLI_1235	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AZOLI_1236	COG0534	Mate efflux family protein
AZOLI_1244	COG1492	cobalamin metabolic process
AZOLI_1245	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AZOLI_1254	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AZOLI_1255	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AZOLI_1261	COG0556	nucleotide-excision repair
AZOLI_1262	COG0741	lytic transglycosylase activity
AZOLI_1271	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AZOLI_1274	COG4957	zinc ion binding
AZOLI_1275	COG0776	regulation of translation
AZOLI_1278	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AZOLI_1280	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AZOLI_1281	COG0540	Belongs to the ATCase OTCase family
AZOLI_1282	COG0583	DNA-binding transcription factor activity
AZOLI_1289	COG0410	ABC transporter
AZOLI_1290	COG4120	Belongs to the binding-protein-dependent transport system permease family
AZOLI_1299	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AZOLI_1300	COG1763	Mo-molybdopterin cofactor biosynthetic process
AZOLI_1301	COG0546	phosphoglycolate phosphatase activity
AZOLI_1303	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AZOLI_1304	COG0314	molybdopterin synthase activity
AZOLI_1305	COG1678	Uncharacterized ACR, COG1678
AZOLI_1307	COG2824	Alkylphosphonate utilization operon protein PhnA
AZOLI_1308	COG0678	peroxiredoxin activity
AZOLI_1310	COG0328	RNA-DNA hybrid ribonuclease activity
AZOLI_1311	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AZOLI_1312	COG2833	Protein of unknown function (DUF455)
AZOLI_1313	COG1218	3'(2'),5'-bisphosphate nucleotidase
AZOLI_1315	COG2200	EAL domain
AZOLI_1317	COG2135	peptidase activity
AZOLI_1321	COG2261	transglycosylase associated protein
AZOLI_1322	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AZOLI_1323	COG0725	ABC transporter, periplasmic molybdate-binding protein
AZOLI_1324	COG4149	molybdate abc transporter
AZOLI_1329	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AZOLI_1330	COG0022	dehydrogenase e1 component
AZOLI_1330	COG0508	dehydrogenase complex catalyzes the overall conversion of
AZOLI_1331	COG0508	dehydrogenase complex catalyzes the overall conversion of
AZOLI_1333	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AZOLI_1335	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AZOLI_1336	COG2867	negative regulation of translational initiation
AZOLI_1337	COG1942	4-Oxalocrotonate Tautomerase
AZOLI_1339	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AZOLI_1339	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AZOLI_1345	COG2204	response regulator
AZOLI_1349	COG1923	regulation of RNA biosynthetic process
AZOLI_1350	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AZOLI_1353	COG0483	inositol monophosphate 1-phosphatase activity
AZOLI_1356	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZOLI_1357	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZOLI_1358	COG1116	anion transmembrane transporter activity
AZOLI_1359	COG0123	including yeast histone deacetylase and acetoin utilization protein
AZOLI_1365	COG0629	single-stranded DNA binding
AZOLI_1366	COG0583	DNA-binding transcription factor activity
AZOLI_1368	COG2814	Major facilitator Superfamily
AZOLI_1373	COG0714	Associated with various cellular activities
AZOLI_1379	COG0248	Ppx GppA phosphatase
AZOLI_1380	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AZOLI_1383	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AZOLI_1387	COG1562	ergosterol biosynthetic process
AZOLI_1388	COG1562	ergosterol biosynthetic process
AZOLI_1389	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AZOLI_1390	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AZOLI_1393	COG3737	Protein of unknown function (DUF498/DUF598)
AZOLI_1395	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AZOLI_1399	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AZOLI_1401	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AZOLI_1403	COG2197	response regulator
AZOLI_1407	COG0840	transmembrane signaling receptor activity
AZOLI_1407	COG3290	protein histidine kinase activity
AZOLI_1408	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AZOLI_1420	COG1028	Short-chain dehydrogenase reductase Sdr
AZOLI_1420	COG0604	alcohol dehydrogenase
AZOLI_1420	COG3321	synthase
AZOLI_1423	COG0288	reversible hydration of carbon dioxide
AZOLI_1428	COG0205	6-phosphofructokinase activity
AZOLI_1432	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AZOLI_1433	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AZOLI_1434	COG5002	protein histidine kinase activity
AZOLI_1434	COG5001	Diguanylate cyclase
AZOLI_1439	COG0114	fumarate hydratase activity
AZOLI_1444	COG2951	lytic endotransglycosylase activity
AZOLI_1449	COG4191	Histidine kinase
AZOLI_1452	COG3346	SURF1 family
AZOLI_1454	COG1845	cytochrome c oxidase, subunit III
AZOLI_1455	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AZOLI_1457	COG0109	protoheme IX farnesyltransferase activity
AZOLI_1458	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AZOLI_1459	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AZOLI_1459	COG1565	acr, cog1565
AZOLI_1461	COG0312	modulator of DNA gyrase
AZOLI_1464	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AZOLI_1465	COG2076	Multidrug Resistance protein
AZOLI_1467	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AZOLI_1472	COG1309	transcriptional regulator
AZOLI_1480	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AZOLI_1483	COG1677	Flagellar hook-basal body complex protein FliE
AZOLI_1484	COG1558	bacterial-type flagellum-dependent cell motility
AZOLI_1485	COG1815	bacterial-type flagellum-dependent cell motility
AZOLI_1489	COG1338	Plays a role in the flagellum-specific transport system
AZOLI_1491	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AZOLI_1493	COG1360	Flagellar Motor Protein
AZOLI_1497	COG1752	Esterase of the alpha-beta hydrolase superfamily
AZOLI_1499	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
AZOLI_1503	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AZOLI_1504	COG0571	ribonuclease III activity
AZOLI_1505	COG0681	Belongs to the peptidase S26 family
AZOLI_1506	COG0736	holo-[acyl-carrier-protein] synthase activity
AZOLI_1507	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AZOLI_1509	COG1758	RNA polymerase activity
AZOLI_1511	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AZOLI_1512	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AZOLI_1515	COG1247	-acetyltransferase
AZOLI_1516	COG0519	Catalyzes the synthesis of GMP from XMP
AZOLI_1526	COG1914	H( )-stimulated, divalent metal cation uptake system
AZOLI_1527	COG2900	Belongs to the SlyX family
AZOLI_1528	COG2132	Multicopper oxidase
AZOLI_1533	COG4953	penicillin-binding protein 1C
AZOLI_1534	COG2373	Large extracellular alpha-helical protein
AZOLI_1537	COG0583	DNA-binding transcription factor activity
AZOLI_1538	COG0303	'Molybdopterin
AZOLI_1539	COG1324	tolerance protein
AZOLI_1541	COG2205	protein histidine kinase activity
AZOLI_1545	COG1494	fructose-1,6-bisphosphatase
AZOLI_1547	COG0436	Aminotransferase
AZOLI_1548	COG0840	transmembrane signaling receptor activity
AZOLI_1548	COG3290	protein histidine kinase activity
AZOLI_1551	COG0745	RESPONSE REGULATOR receiver
AZOLI_1553	COG0616	signal peptide processing
AZOLI_1554	COG0488	(ABC) transporter
AZOLI_1555	COG3932	Exopolysaccharide synthesis, ExoD
AZOLI_1558	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AZOLI_1559	COG0525	valine-tRNA ligase activity
AZOLI_1561	COG1538	Outer membrane efflux protein
AZOLI_1563	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AZOLI_1570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AZOLI_1571	COG0494	nUDIX hydrolase
AZOLI_1574	COG2897	thiosulfate sulfurtransferase activity
AZOLI_1575	COG0456	acetyltransferase
AZOLI_1575	COG1214	PFAM Peptidase M22, glycoprotease
AZOLI_1579	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AZOLI_1580	COG1126	abc transporter atp-binding protein
AZOLI_1581	COG0765	amino acid transport
AZOLI_1582	COG4597	amino acid ABC transporter
AZOLI_1583	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZOLI_1584	COG0626	cystathionine gamma-synthase activity
AZOLI_1596	COG2308	Evidence 4 Homologs of previously reported genes of
AZOLI_1597	COG1360	Flagellar Motor Protein
AZOLI_1598	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AZOLI_1602	COG0318	PFAM AMP-dependent synthetase and ligase
AZOLI_1603	COG0789	Transcriptional regulator
AZOLI_1605	COG2086	electron transfer activity
AZOLI_1609	COG4191	Histidine kinase
AZOLI_1610	COG2205	protein histidine kinase activity
AZOLI_1611	COG0728	peptidoglycan biosynthetic process
AZOLI_1616	COG1765	OsmC-like protein
AZOLI_1617	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AZOLI_1619	COG5487	UPF0391 membrane protein
AZOLI_1622	COG1196	nuclear chromosome segregation
AZOLI_1622	COG0741	lytic transglycosylase activity
AZOLI_1622	COG0739	heme binding
AZOLI_1625	COG2226	methyltransferase
AZOLI_1627	COG0513	Belongs to the DEAD box helicase family
AZOLI_1631	COG0187	DNA topoisomerase II activity
AZOLI_1632	COG1607	acyl-coa hydrolase
AZOLI_1634	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZOLI_1635	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZOLI_1642	COG4191	Histidine kinase
AZOLI_1642	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZOLI_1645	COG3437	response regulator, receiver
AZOLI_1645	COG0784	Response regulator, receiver
AZOLI_1647	COG3293	Transposase
AZOLI_1649	COG0140	phosphoribosyl-ATP diphosphatase activity
AZOLI_1658	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AZOLI_1660	COG0643	Histidine kinase
AZOLI_1660	COG2198	Histidine kinase
AZOLI_1661	COG2201	protein-glutamate methylesterase activity
AZOLI_1662	COG2201	protein-glutamate methylesterase activity
AZOLI_1663	COG0835	chemotaxis
AZOLI_1665	COG3290	protein histidine kinase activity
AZOLI_1665	COG0840	transmembrane signaling receptor activity
AZOLI_1666	COG3290	protein histidine kinase activity
AZOLI_1666	COG0840	transmembrane signaling receptor activity
AZOLI_1669	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AZOLI_1670	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AZOLI_1674	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AZOLI_1676	COG0360	Binds together with S18 to 16S ribosomal RNA
AZOLI_1677	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AZOLI_1679	COG0359	binds to the 23S rRNA
AZOLI_1680	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AZOLI_1681	COG0538	isocitrate dehydrogenase activity
AZOLI_1683	COG0330	HflC and HflK could
AZOLI_1690	COG0473	3-isopropylmalate dehydrogenase activity
AZOLI_1704	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AZOLI_1721	COG1686	Belongs to the peptidase S11 family
AZOLI_1722	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AZOLI_1723	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AZOLI_1724	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AZOLI_1725	COG0084	hydrolase, TatD family'
AZOLI_1726	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AZOLI_1726	COG0321	lipoyl(octanoyl) transferase activity
AZOLI_1727	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AZOLI_1731	COG1381	Involved in DNA repair and RecF pathway recombination
AZOLI_1732	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AZOLI_1738	COG4786	Flagellar basal body rod
AZOLI_1739	COG4786	Flagellar basal body rod
AZOLI_1741	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AZOLI_1757	COG3772	lysozyme
AZOLI_1782	COG0305	Participates in initiation and elongation during chromosome replication
AZOLI_1798	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AZOLI_1807	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AZOLI_1808	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AZOLI_1811	COG1024	Enoyl-CoA hydratase
AZOLI_1814	COG0758	DNA mediated transformation
AZOLI_1815	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AZOLI_1817	COG1024	Enoyl-CoA hydratase
AZOLI_1818	COG1832	CoA-binding protein
AZOLI_1823	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AZOLI_1831	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AZOLI_1833	COG3706	GGDEF domain
AZOLI_1833	COG0745	RESPONSE REGULATOR receiver
AZOLI_1834	COG0784	Response regulator, receiver
AZOLI_1835	COG3447	MASE1 domain protein
AZOLI_1835	COG5001	Diguanylate cyclase
AZOLI_1835	COG5002	protein histidine kinase activity
AZOLI_1839	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AZOLI_1842	COG1238	metal cluster binding
AZOLI_1843	COG0203	ribosomal protein L17
AZOLI_1846	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AZOLI_1851	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AZOLI_1852	COG0251	oxidation-reduction process
AZOLI_1864	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AZOLI_1864	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AZOLI_1872	COG0154	amidase activity
AZOLI_1873	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AZOLI_1876	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AZOLI_1878	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
AZOLI_1884	COG0242	peptide deformylase activity
AZOLI_1885	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AZOLI_1886	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AZOLI_1889	COG1201	RNA secondary structure unwinding
AZOLI_1892	COG0415	Belongs to the DNA photolyase family
AZOLI_1893	COG0735	belongs to the Fur family
AZOLI_1894	COG0523	cobalamin synthesis protein
AZOLI_1896	COG0840	transmembrane signaling receptor activity
AZOLI_1897	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AZOLI_1900	COG2205	protein histidine kinase activity
AZOLI_1902	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AZOLI_1904	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AZOLI_1904	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AZOLI_1909	COG0497	DNA recombination
AZOLI_1910	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AZOLI_1914	COG0745	RESPONSE REGULATOR receiver
AZOLI_1915	COG0006	proline dipeptidase activity
AZOLI_1917	COG2264	protein methyltransferase activity
AZOLI_1919	COG0210	DNA helicase
AZOLI_1921	COG2197	response regulator
AZOLI_1922	COG2197	response regulator
AZOLI_1931	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AZOLI_1940	COG2910	NAD(P)H-binding
AZOLI_1946	COG0742	ribosomal rna small subunit methyltransferase
AZOLI_1947	COG1187	pseudouridine synthase activity
AZOLI_1948	COG0590	tRNA wobble adenosine to inosine editing
AZOLI_1952	COG1570	exodeoxyribonuclease VII activity
AZOLI_1953	COG1053	succinate dehydrogenase
AZOLI_1955	COG0418	dihydroorotase activity
AZOLI_1959	COG0300	oxidoreductase activity
AZOLI_1960	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AZOLI_1961	COG0193	aminoacyl-tRNA hydrolase activity
AZOLI_1962	COG0012	GTP binding
AZOLI_1963	COG1283	sodium-dependent phosphate transmembrane transporter activity
AZOLI_1966	COG0583	DNA-binding transcription factor activity
AZOLI_1973	COG2945	thiolester hydrolase activity
AZOLI_1974	COG1045	serine acetyltransferase
AZOLI_1978	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AZOLI_1980	COG0482	sulfurtransferase activity
AZOLI_1982	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AZOLI_1994	COG5489	Protein of unknown function (DUF736)
AZOLI_1997	COG1396	sequence-specific DNA binding
AZOLI_2012	COG1074	ATP-dependent DNA helicase activity
AZOLI_2020	COG1518	maintenance of DNA repeat elements
AZOLI_2020	COG1468	defense response to virus
AZOLI_2021	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AZOLI_2026	COG2894	cell division
AZOLI_2043	COG4191	Histidine kinase
AZOLI_2050	COG2192	nodulation
AZOLI_2057	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
AZOLI_2058	COG0732	type I restriction modification DNA specificity domain
AZOLI_2059	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AZOLI_2071	COG0582	viral genome integration into host DNA
AZOLI_2098	COG0464	growth
AZOLI_2101	COG1028	Short-chain dehydrogenase reductase Sdr
AZOLI_2102	COG0534	Mate efflux family protein
AZOLI_2103	COG1309	transcriptional regulator
AZOLI_2108	COG0745	RESPONSE REGULATOR receiver
AZOLI_2108	COG3706	GGDEF domain
AZOLI_2109	COG3284	Transcriptional regulator
AZOLI_2118	COG4636	protein conserved in cyanobacteria
AZOLI_2121	COG2001	Belongs to the MraZ family
AZOLI_2125	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AZOLI_2127	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AZOLI_2128	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AZOLI_2130	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AZOLI_2132	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AZOLI_2133	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AZOLI_2134	COG1181	Belongs to the D-alanine--D-alanine ligase family
AZOLI_2135	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AZOLI_2136	COG0849	cell division
AZOLI_2137	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AZOLI_2143	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AZOLI_2149	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AZOLI_2150	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AZOLI_2153	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AZOLI_2157	COG2954	triphosphatase activity
AZOLI_2161	COG1183	phosphatidylcholine synthase activity
AZOLI_2169	COG0354	folic acid binding
AZOLI_2172	COG0546	phosphoglycolate phosphatase activity
AZOLI_2173	COG0564	pseudouridine synthase activity
AZOLI_2174	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AZOLI_2175	COG1335	isochorismatase
AZOLI_2177	COG1136	(ABC) transporter
AZOLI_2180	COG0442	prolyl-tRNA aminoacylation
AZOLI_2186	COG0519	Catalyzes the synthesis of GMP from XMP
AZOLI_2193	COG1007	ATP synthesis coupled electron transport
AZOLI_2196	COG0713	ATP synthesis coupled electron transport
AZOLI_2199	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AZOLI_2200	COG1034	ATP synthesis coupled electron transport
AZOLI_2202	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AZOLI_2203	COG0649	NAD binding
AZOLI_2204	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AZOLI_2205	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AZOLI_2206	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AZOLI_2221	COG0500	methyltransferase
AZOLI_2222	COG0140	phosphoribosyl-ATP diphosphatase activity
AZOLI_2224	COG0704	Plays a role in the regulation of phosphate uptake
AZOLI_2226	COG2862	Uncharacterized protein family, UPF0114
AZOLI_2231	COG0768	penicillin binding
AZOLI_2232	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AZOLI_2237	COG0028	Belongs to the TPP enzyme family
AZOLI_2238	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZOLI_2239	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AZOLI_2240	COG3830	Belongs to the UPF0237 family
AZOLI_2240	COG0560	Phosphoserine phosphatase
AZOLI_2242	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AZOLI_2246	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AZOLI_2247	COG0830	nickel cation binding
AZOLI_2248	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AZOLI_2249	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AZOLI_2250	COG0804	urea catabolic process
AZOLI_2251	COG0832	Belongs to the urease beta subunit family
AZOLI_2252	COG0831	urea catabolic process
AZOLI_2253	COG0829	nickel cation binding
AZOLI_2254	COG2197	response regulator
AZOLI_2256	COG2197	response regulator
AZOLI_2257	COG0693	protein deglycase activity
AZOLI_2260	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AZOLI_2261	COG0717	Belongs to the dCTP deaminase family
AZOLI_2266	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AZOLI_2271	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AZOLI_2273	COG0557	exoribonuclease II activity
AZOLI_2274	COG0793	Belongs to the peptidase S41A family
AZOLI_2275	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AZOLI_2276	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AZOLI_2281	COG1380	Effector of murein hydrolase LrgA
AZOLI_2282	COG1346	cytolysis
AZOLI_2284	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AZOLI_2290	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AZOLI_2296	COG3381	protein complex oligomerization
AZOLI_2297	COG0784	Response regulator, receiver
AZOLI_2297	COG4191	Histidine kinase
AZOLI_2303	COG1131	(ABC) transporter
AZOLI_2305	COG1309	transcriptional regulator
AZOLI_2312	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AZOLI_2315	COG5554	nitrogen fixation
AZOLI_2320	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AZOLI_2324	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AZOLI_2326	COG0745	RESPONSE REGULATOR receiver
AZOLI_2327	COG2176	DNA-directed DNA polymerase activity
AZOLI_2327	COG5002	protein histidine kinase activity
AZOLI_2329	COG5002	protein histidine kinase activity
AZOLI_2331	COG2204	response regulator
AZOLI_2332	COG3852	Histidine kinase
AZOLI_2334	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AZOLI_2343	COG0752	glycyl-tRNA synthetase alpha subunit
AZOLI_2344	COG0751	glycine-tRNA ligase activity
AZOLI_2345	COG0312	modulator of DNA gyrase
AZOLI_2347	COG0004	ammonium transporteR
AZOLI_2348	COG0047	phosphoribosylformylglycinamidine synthase activity
AZOLI_2349	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AZOLI_2361	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AZOLI_2364	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AZOLI_2364	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AZOLI_2368	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AZOLI_2370	COG0463	Glycosyl transferase, family 2
AZOLI_2371	COG0840	transmembrane signaling receptor activity
AZOLI_2373	COG0840	transmembrane signaling receptor activity
AZOLI_2376	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AZOLI_2381	COG3118	belongs to the thioredoxin family
AZOLI_2383	COG2835	tetraacyldisaccharide 4'-kinase activity
AZOLI_2385	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AZOLI_2387	COG1028	Short-chain dehydrogenase reductase Sdr
AZOLI_2388	COG0183	Belongs to the thiolase family
AZOLI_2389	COG3243	poly(R)-hydroxyalkanoic acid synthase
AZOLI_2391	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
AZOLI_2396	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
AZOLI_2398	COG0842	Transport permease protein
AZOLI_2399	COG1132	(ABC) transporter
AZOLI_2400	COG2311	Membrane
AZOLI_2401	COG1309	transcriptional regulator
AZOLI_2402	COG0254	rRNA binding
AZOLI_2404	COG0071	Belongs to the small heat shock protein (HSP20) family
AZOLI_2408	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AZOLI_2409	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AZOLI_2411	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AZOLI_2413	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AZOLI_2415	COG0793	Belongs to the peptidase S41A family
AZOLI_2416	COG4942	peptidase
AZOLI_2417	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AZOLI_2418	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AZOLI_2419	COG0799	negative regulation of ribosome biogenesis
AZOLI_2423	COG1051	belongs to the nudix hydrolase family
AZOLI_2425	COG0745	RESPONSE REGULATOR receiver
AZOLI_2426	COG2198	Histidine kinase
AZOLI_2426	COG0643	Histidine kinase
AZOLI_2427	COG0835	chemotaxis
AZOLI_2428	COG0840	transmembrane signaling receptor activity
AZOLI_2430	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AZOLI_2431	COG2201	protein-glutamate methylesterase activity
AZOLI_2432	COG0840	transmembrane signaling receptor activity
AZOLI_2433	COG1366	Belongs to the anti-sigma-factor antagonist family
AZOLI_2436	COG3706	GGDEF domain
AZOLI_2436	COG0745	RESPONSE REGULATOR receiver
AZOLI_2437	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AZOLI_2438	COG0579	oxidoreductase
AZOLI_2439	COG0071	Belongs to the small heat shock protein (HSP20) family
AZOLI_2445	COG1322	Protein conserved in bacteria
AZOLI_2449	COG1028	Short-chain dehydrogenase reductase Sdr
AZOLI_2459	COG1278	Cold shock
AZOLI_2460	COG1902	pentaerythritol trinitrate reductase activity
AZOLI_2461	COG0328	RNA-DNA hybrid ribonuclease activity
AZOLI_2461	COG0406	alpha-ribazole phosphatase activity
AZOLI_2462	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AZOLI_2465	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AZOLI_2468	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AZOLI_2469	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AZOLI_2473	COG2193	ferroxidase activity
AZOLI_2475	COG1192	Involved in chromosome partitioning
AZOLI_2476	COG0009	L-threonylcarbamoyladenylate synthase
AZOLI_2478	COG0277	FAD linked oxidase domain protein
AZOLI_2482	COG0559	Belongs to the binding-protein-dependent transport system permease family
AZOLI_2484	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AZOLI_2485	COG0747	negative chemotaxis
AZOLI_2488	COG4191	Histidine kinase
AZOLI_2490	COG0101	tRNA pseudouridine synthase activity
AZOLI_2491	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AZOLI_2492	COG0242	peptide deformylase activity
AZOLI_2493	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AZOLI_2496	COG0513	Belongs to the DEAD box helicase family
AZOLI_2501	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AZOLI_2503	COG2084	Dehydrogenase
AZOLI_2508	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AZOLI_2508	COG1199	ATP-dependent helicase activity
AZOLI_2509	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AZOLI_2511	COG1595	DNA-templated transcription, initiation
AZOLI_2514	COG3706	GGDEF domain
AZOLI_2514	COG0745	RESPONSE REGULATOR receiver
AZOLI_2515	COG0784	Response regulator, receiver
AZOLI_2515	COG2205	protein histidine kinase activity
AZOLI_2515	COG5002	protein histidine kinase activity
AZOLI_2518	COG3279	Response regulator of the LytR AlgR family
AZOLI_2523	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AZOLI_2526	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AZOLI_2529	COG2350	Protein conserved in bacteria
AZOLI_2533	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AZOLI_2536	COG2205	protein histidine kinase activity
AZOLI_2538	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AZOLI_2541	COG2885	chlorophyll binding
AZOLI_2543	COG0586	Pfam SNARE associated Golgi protein
AZOLI_2545	COG0517	IMP dehydrogenase activity
AZOLI_2545	COG0516	GMP reductase activity
AZOLI_2547	COG1278	Cold shock
AZOLI_2553	COG0625	glutathione transferase activity
AZOLI_2554	COG0410	ABC transporter
AZOLI_2557	COG0559	Belongs to the binding-protein-dependent transport system permease family
AZOLI_2560	COG3327	negative regulation of DNA-templated transcription, initiation
AZOLI_2564	COG0840	transmembrane signaling receptor activity
AZOLI_2566	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AZOLI_2571	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AZOLI_2574	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AZOLI_2575	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AZOLI_2579	COG0167	dihydroorotate dehydrogenase activity
AZOLI_2596	COG2032	superoxide dismutase activity
AZOLI_2598	COG0513	Belongs to the DEAD box helicase family
AZOLI_2599	COG0625	glutathione transferase activity
AZOLI_2601	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AZOLI_2603	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AZOLI_2605	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AZOLI_2611	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AZOLI_2613	COG4974	Belongs to the 'phage' integrase family
AZOLI_2614	COG0840	transmembrane signaling receptor activity
AZOLI_2619	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AZOLI_2622	COG1278	Cold shock
AZOLI_2625	COG4191	Histidine kinase
AZOLI_2627	COG4106	trans-aconitate 2-methyltransferase activity
AZOLI_2630	COG0126	phosphoglycerate kinase activity
AZOLI_2633	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AZOLI_2637	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AZOLI_2641	COG0825	malonyl-CoA metabolic process
AZOLI_2642	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AZOLI_2651	COG2205	protein histidine kinase activity
AZOLI_2651	COG2202	Pas domain
AZOLI_2654	COG3830	Belongs to the UPF0237 family
AZOLI_2654	COG0560	Phosphoserine phosphatase
AZOLI_2656	COG1595	DNA-templated transcription, initiation
AZOLI_2657	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AZOLI_2660	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AZOLI_2663	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AZOLI_2666	COG1695	Transcriptional regulator
AZOLI_2668	COG0492	ferredoxin-NADP+ reductase activity
AZOLI_2669	COG0601	transmembrane transport
AZOLI_2671	COG0444	Belongs to the ABC transporter superfamily
AZOLI_2672	COG4608	Belongs to the ABC transporter superfamily
AZOLI_2675	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AZOLI_2678	COG0583	DNA-binding transcription factor activity
AZOLI_2679	COG0604	alcohol dehydrogenase
AZOLI_2681	COG4566	intracellular signal transduction
AZOLI_2685	COG0459	protein refolding
AZOLI_2686	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AZOLI_2688	COG5425	PFAM Usg family protein
AZOLI_2690	COG3772	lysozyme
AZOLI_2691	COG1612	heme a metabolic process
AZOLI_2692	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AZOLI_2694	COG2217	Heavy metal translocating P-type atpase
AZOLI_2700	COG3278	Belongs to the heme-copper respiratory oxidase family
AZOLI_2703	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AZOLI_2708	COG1177	transmembrane transport
AZOLI_2709	COG1176	ABC-type spermidine putrescine transport system, permease component I
AZOLI_2712	COG0156	8-amino-7-oxononanoate synthase activity
AZOLI_2715	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AZOLI_2716	COG0745	RESPONSE REGULATOR receiver
AZOLI_2716	COG3706	GGDEF domain
AZOLI_2717	COG0135	phosphoribosylanthranilate isomerase activity
AZOLI_2720	COG5265	(ABC) transporter
AZOLI_2721	COG0840	transmembrane signaling receptor activity
AZOLI_2732	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AZOLI_2734	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AZOLI_2736	COG0861	Integral membrane protein TerC family
AZOLI_2739	COG0583	DNA-binding transcription factor activity
AZOLI_2740	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AZOLI_2744	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AZOLI_2745	COG0138	bifunctional purine biosynthesis protein purh
AZOLI_2747	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AZOLI_2747	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AZOLI_2748	COG1024	Enoyl-CoA hydratase
AZOLI_2749	COG0477	Major facilitator Superfamily
AZOLI_2751	COG0583	DNA-binding transcription factor activity
AZOLI_2754	COG1272	protein, Hemolysin III
AZOLI_2761	COG0137	argininosuccinate synthase activity
AZOLI_2766	COG0667	Aldo Keto reductase
AZOLI_2772	COG2423	ornithine cyclodeaminase activity
AZOLI_2774	COG0776	regulation of translation
AZOLI_2777	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AZOLI_2785	COG0783	Belongs to the Dps family
AZOLI_2788	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AZOLI_2809	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AZOLI_2819	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AZOLI_2822	COG3437	response regulator, receiver
AZOLI_2822	COG0784	Response regulator, receiver
AZOLI_2823	COG3813	Protein conserved in bacteria
AZOLI_2824	COG0625	glutathione transferase activity
AZOLI_2825	COG1473	amidohydrolase
AZOLI_2827	COG5001	Diguanylate cyclase
AZOLI_2835	COG1040	competence protein
AZOLI_2837	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AZOLI_2842	COG3162	membrane
AZOLI_2847	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AZOLI_2849	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AZOLI_2850	COG0542	response to heat
AZOLI_2855	COG2890	protein-(glutamine-N5) methyltransferase activity
AZOLI_2856	COG2852	Protein conserved in bacteria
AZOLI_2858	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AZOLI_2859	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AZOLI_2862	COG2070	2-Nitropropane dioxygenase
AZOLI_2863	COG0527	aspartate kinase activity
AZOLI_2864	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AZOLI_2869	COG4636	protein conserved in cyanobacteria
AZOLI_2870	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AZOLI_2871	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AZOLI_2872	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AZOLI_2873	COG1137	ATPase activity
AZOLI_2876	COG0517	IMP dehydrogenase activity
AZOLI_2876	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AZOLI_2883	COG2223	nitrite transmembrane transporter activity
AZOLI_2894	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AZOLI_2896	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AZOLI_2897	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AZOLI_2898	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AZOLI_2900	COG1573	uracil-dna glycosylase
AZOLI_2902	COG2154	pterin-4-alpha-carbinolamine dehydratase
AZOLI_2903	COG0840	transmembrane signaling receptor activity
AZOLI_2903	COG2972	Histidine kinase
AZOLI_2904	COG4166	transmembrane transport
AZOLI_2905	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AZOLI_2908	COG0039	L-malate dehydrogenase activity
AZOLI_2917	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AZOLI_2919	COG0598	Magnesium transport protein CorA
AZOLI_2920	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AZOLI_2921	COG1872	DUF167
AZOLI_2925	COG0285	dihydrofolate synthase activity
AZOLI_2926	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AZOLI_2930	COG0133	tryptophan synthase activity
AZOLI_2931	COG2205	protein histidine kinase activity
AZOLI_2931	COG0784	Response regulator, receiver
AZOLI_2932	COG1278	Cold shock
AZOLI_2933	COG2204	response regulator
AZOLI_2934	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AZOLI_2935	COG0756	dUTP diphosphatase activity
AZOLI_2936	COG2205	protein histidine kinase activity
AZOLI_2936	COG5002	protein histidine kinase activity
AZOLI_2936	COG0784	Response regulator, receiver
AZOLI_2940	COG4974	Belongs to the 'phage' integrase family
AZOLI_2944	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AZOLI_2949	COG0271	Belongs to the BolA IbaG family
AZOLI_2954	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AZOLI_2955	COG0501	Belongs to the peptidase M48B family
AZOLI_2958	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AZOLI_2959	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AZOLI_2961	COG1660	Displays ATPase and GTPase activities
AZOLI_2965	COG0642	Histidine kinase
AZOLI_2966	COG0745	RESPONSE REGULATOR receiver
AZOLI_2969	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AZOLI_2982	COG4957	zinc ion binding
AZOLI_2985	COG1214	PFAM Peptidase M22, glycoprotease
AZOLI_2986	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AZOLI_2990	COG0443	Heat shock 70 kDa protein
AZOLI_2995	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AZOLI_2997	COG0667	Aldo Keto reductase
AZOLI_3000	COG4181	ATPase activity
AZOLI_3002	COG0670	Belongs to the BI1 family
AZOLI_3004	COG0745	RESPONSE REGULATOR receiver
AZOLI_3005	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AZOLI_3007	COG0573	inorganic phosphate transmembrane transporter activity
AZOLI_3008	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AZOLI_3010	COG5002	protein histidine kinase activity
AZOLI_3014	COG0281	malic enzyme
AZOLI_3014	COG0280	phosphate acetyltransferase
AZOLI_3015	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AZOLI_3016	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AZOLI_3017	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AZOLI_3018	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AZOLI_3019	COG1475	DNA binding
AZOLI_3020	COG1192	Involved in chromosome partitioning
AZOLI_3021	COG0357	Ribosomal RNA small subunit methyltransferase G
AZOLI_3022	COG0445	tRNA wobble uridine modification
AZOLI_3026	COG1331	Highly conserved protein containing a thioredoxin domain
AZOLI_3027	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AZOLI_3029	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AZOLI_3036	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AZOLI_3038	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AZOLI_3039	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AZOLI_3042	COG4395	Tim44
AZOLI_3043	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AZOLI_3044	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AZOLI_3057	COG4235	cytochrome complex assembly
AZOLI_3058	COG3088	subunit of a heme lyase
AZOLI_3059	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AZOLI_3060	COG1138	Cytochrome C-type biogenesis protein
AZOLI_3061	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AZOLI_3063	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AZOLI_3067	COG1028	Short-chain dehydrogenase reductase Sdr
AZOLI_3068	COG1185	polyribonucleotide nucleotidyltransferase activity
AZOLI_3070	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AZOLI_3071	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AZOLI_3078	COG0779	Required for maturation of 30S ribosomal subunits
AZOLI_3079	COG2329	Antibiotic biosynthesis monooxygenase
AZOLI_3080	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AZOLI_3081	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AZOLI_3082	COG1396	sequence-specific DNA binding
AZOLI_3083	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AZOLI_3084	COG1253	flavin adenine dinucleotide binding
AZOLI_3086	COG1702	phosphate starvation-inducible protein PhoH
AZOLI_3087	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AZOLI_3089	COG2967	ApaG domain
AZOLI_3091	COG0302	gtp cyclohydrolase
AZOLI_3092	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AZOLI_3094	COG0668	transmembrane transport
AZOLI_3098	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AZOLI_3101	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AZOLI_3104	COG0730	response to heat
AZOLI_3107	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AZOLI_3109	COG0745	RESPONSE REGULATOR receiver
AZOLI_3111	COG1420	regulation of RNA biosynthetic process
AZOLI_3113	COG0606	chelatase, subunit chli
AZOLI_3120	COG0180	Tryptophanyl-tRNA synthetase
AZOLI_3123	COG0792	nuclease activity
AZOLI_3124	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AZOLI_3131	COG2985	domain, Protein
AZOLI_3131	COG0569	domain protein
AZOLI_3134	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AZOLI_3135	COG0386	Belongs to the glutathione peroxidase family
AZOLI_3139	COG0739	heme binding
AZOLI_3150	COG0859	PFAM glycosyl transferase family 9
AZOLI_3153	COG0187	DNA topoisomerase II activity
AZOLI_3154	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AZOLI_3155	COG0592	DNA-directed DNA polymerase activity
AZOLI_3159	COG3118	belongs to the thioredoxin family
AZOLI_3160	COG1074	ATP-dependent DNA helicase activity
AZOLI_3163	COG2887	Belongs to the helicase family. UvrD subfamily
AZOLI_3164	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AZOLI_3166	COG0802	atpase or kinase
AZOLI_3169	COG0747	negative chemotaxis
AZOLI_3174	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AZOLI_3176	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AZOLI_3178	COG1024	Enoyl-CoA hydratase
AZOLI_p10012	COG1522	sequence-specific DNA binding
AZOLI_p10015	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AZOLI_p10015	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AZOLI_p10018	COG0564	pseudouridine synthase activity
AZOLI_p10019	COG2205	protein histidine kinase activity
AZOLI_p10019	COG0784	Response regulator, receiver
AZOLI_p10020	COG1741	Belongs to the pirin family
AZOLI_p10022	COG3768	UPF0283 membrane protein
AZOLI_p10023	COG3106	COG3106 Predicted ATPase
AZOLI_p10026	COG1024	Enoyl-CoA hydratase
AZOLI_p10027	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AZOLI_p10028	COG1960	acyl-CoA dehydrogenase activity
AZOLI_p10029	COG0183	Belongs to the thiolase family
AZOLI_p10030	COG1960	acyl-CoA dehydrogenase activity
AZOLI_p10036	COG2205	protein histidine kinase activity
AZOLI_p10037	COG0583	DNA-binding transcription factor activity
AZOLI_p10041	COG1120	ATPase activity
AZOLI_p10042	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AZOLI_p10045	COG2902	Dehydrogenase
AZOLI_p10046	COG2207	Transcriptional regulator
AZOLI_p10053	COG1192	Involved in chromosome partitioning
AZOLI_p10054	COG1475	DNA binding
AZOLI_p10055	COG0747	negative chemotaxis
AZOLI_p10057	COG5000	phosphorelay sensor kinase activity
AZOLI_p10057	COG5002	protein histidine kinase activity
AZOLI_p10058	COG2202	Pas domain
AZOLI_p10058	COG2205	protein histidine kinase activity
AZOLI_p10067	COG0583	DNA-binding transcription factor activity
AZOLI_p10070	COG3383	formate dehydrogenase (NAD+) activity
AZOLI_p10071	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AZOLI_p10078	COG0411	ABC transporter
AZOLI_p10079	COG0410	ABC transporter
AZOLI_p10084	COG0625	glutathione transferase activity
AZOLI_p10085	COG0583	DNA-binding transcription factor activity
AZOLI_p10087	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AZOLI_p10093	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AZOLI_p10094	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AZOLI_p10095	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AZOLI_p10096	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AZOLI_p10097	COG2885	chlorophyll binding
AZOLI_p10097	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AZOLI_p10101	COG0366	Alpha amylase catalytic
AZOLI_p10102	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AZOLI_p10107	COG1640	4-alpha-glucanotransferase
AZOLI_p10109	COG3293	Transposase
AZOLI_p10161	COG4974	Belongs to the 'phage' integrase family
AZOLI_p10177	COG0745	RESPONSE REGULATOR receiver
AZOLI_p10178	COG2205	protein histidine kinase activity
AZOLI_p10187	COG2205	protein histidine kinase activity
AZOLI_p10189	COG0840	transmembrane signaling receptor activity
AZOLI_p10190	COG1309	transcriptional regulator
AZOLI_p10191	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AZOLI_p10195	COG0559	Belongs to the binding-protein-dependent transport system permease family
AZOLI_p10199	COG0318	PFAM AMP-dependent synthetase and ligase
AZOLI_p10200	COG0435	Glutathione S-transferase
AZOLI_p10203	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AZOLI_p10204	COG2342	PFAM TM1410 hypothetical-related protein
AZOLI_p10211	COG0297	glycogen (starch) synthase activity
AZOLI_p10215	COG3293	Transposase
AZOLI_p10223	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AZOLI_p10228	COG0583	DNA-binding transcription factor activity
AZOLI_p10229	COG1028	Short-chain dehydrogenase reductase Sdr
AZOLI_p10230	COG3959	Transketolase, thiamine diphosphate binding domain
AZOLI_p10231	COG3958	Transketolase
AZOLI_p10232	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AZOLI_p10233	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AZOLI_p10234	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AZOLI_p10235	COG2084	Dehydrogenase
AZOLI_p10236	COG0066	3-isopropylmalate dehydratase activity
AZOLI_p10237	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AZOLI_p10238	COG1053	succinate dehydrogenase
AZOLI_p10239	COG1335	isochorismatase
AZOLI_p10246	COG0559	Belongs to the binding-protein-dependent transport system permease family
AZOLI_p10248	COG2188	Transcriptional regulator
AZOLI_p10250	COG2972	Histidine kinase
AZOLI_p10250	COG0840	transmembrane signaling receptor activity
AZOLI_p10251	COG0488	(ABC) transporter
AZOLI_p10253	COG1454	alcohol dehydrogenase
AZOLI_p10253	COG1012	belongs to the aldehyde dehydrogenase family
AZOLI_p10259	COG4991	sh3 domain protein
AZOLI_p10259	COG3064	Membrane
AZOLI_p10259	COG0515	serine threonine protein kinase
AZOLI_p10260	COG3243	poly(R)-hydroxyalkanoic acid synthase
AZOLI_p10262	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZOLI_p10265	COG0678	peroxiredoxin activity
AZOLI_p10268	COG0148	phosphopyruvate hydratase activity
AZOLI_p10269	COG0596	Alpha beta hydrolase
AZOLI_p10270	COG0728	peptidoglycan biosynthetic process
AZOLI_p10272	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AZOLI_p10276	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AZOLI_p10277	COG4191	Histidine kinase
AZOLI_p10279	COG0803	Belongs to the bacterial solute-binding protein 9 family
AZOLI_p10280	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AZOLI_p10281	COG1121	(ABC) transporter
AZOLI_p10289	COG0352	thiamine-phosphate diphosphorylase activity
AZOLI_p10290	COG1802	Transcriptional regulator
AZOLI_p10292	COG2084	Dehydrogenase
AZOLI_p10301	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AZOLI_p10302	COG0517	IMP dehydrogenase activity
AZOLI_p10303	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AZOLI_p10304	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AZOLI_p10305	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AZOLI_p10306	COG3195	allantoin biosynthetic process
AZOLI_p10306	COG3648	Uricase
AZOLI_p10309	COG2351	hydroxyisourate hydrolase activity
AZOLI_p10310	COG3960	tartronate-semialdehyde synthase activity
AZOLI_p10311	COG0840	transmembrane signaling receptor activity
AZOLI_p10316	COG1414	Transcriptional regulator
AZOLI_p10317	COG1802	Transcriptional regulator
AZOLI_p10319	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AZOLI_p10320	COG0045	succinate-CoA ligase (ADP-forming) activity
AZOLI_p10321	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AZOLI_p10322	COG1414	Transcriptional regulator
AZOLI_p10333	COG0784	Response regulator, receiver
AZOLI_p10339	COG0697	spore germination
AZOLI_p10340	COG0747	negative chemotaxis
AZOLI_p10342	COG0601	transmembrane transport
AZOLI_p10343	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZOLI_p10344	COG0444	Belongs to the ABC transporter superfamily
AZOLI_p10345	COG4608	Belongs to the ABC transporter superfamily
AZOLI_p10347	COG1666	GTP binding
AZOLI_p10350	COG2890	protein-(glutamine-N5) methyltransferase activity
AZOLI_p10352	COG0142	geranyltranstransferase activity
AZOLI_p10354	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AZOLI_p10356	COG2860	membrane
AZOLI_p10358	COG2217	Heavy metal translocating P-type atpase
AZOLI_p10359	COG0789	Transcriptional regulator
AZOLI_p10363	COG2814	Major facilitator Superfamily
AZOLI_p10367	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AZOLI_p10369	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AZOLI_p10372	COG0402	S-adenosylhomocysteine deaminase activity
AZOLI_p10374	COG4603	Belongs to the binding-protein-dependent transport system permease family
AZOLI_p10379	COG1414	Transcriptional regulator
AZOLI_p10380	COG3842	ATPase activity
AZOLI_p10381	COG1176	ABC-type spermidine putrescine transport system, permease component I
AZOLI_p10382	COG1177	transmembrane transport
AZOLI_p10388	COG2133	pyrroloquinoline quinone binding
AZOLI_p10389	COG0459	protein refolding
AZOLI_p10390	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AZOLI_p10391	COG1063	alcohol dehydrogenase
AZOLI_p10392	COG0673	inositol 2-dehydrogenase activity
AZOLI_p10393	COG1176	ABC-type spermidine putrescine transport system, permease component I
AZOLI_p10394	COG1840	ABC-type Fe3 transport system, periplasmic component
AZOLI_p10395	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AZOLI_p10397	COG3842	ATPase activity
AZOLI_p10398	COG1177	transmembrane transport
AZOLI_p10399	COG1176	ABC-type spermidine putrescine transport system, permease component I
AZOLI_p10405	COG4774	siderophore transport
AZOLI_p10407	COG1595	DNA-templated transcription, initiation
AZOLI_p10413	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AZOLI_p10448	COG0582	viral genome integration into host DNA
AZOLI_p10449	COG4396	Host-nuclease inhibitor protein Gam
AZOLI_p10482	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AZOLI_p10483	COG2223	nitrite transmembrane transporter activity
AZOLI_p10484	COG3546	catalase activity
AZOLI_p10490	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AZOLI_p10491	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AZOLI_p10492	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AZOLI_p10493	COG0295	cytidine deaminase activity
AZOLI_p10496	COG3411	Ferredoxin
AZOLI_p10497	COG0697	spore germination
AZOLI_p10499	COG0559	Belongs to the binding-protein-dependent transport system permease family
AZOLI_p10500	COG0411	ABC transporter
AZOLI_p10503	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZOLI_p10505	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AZOLI_p10508	COG0673	inositol 2-dehydrogenase activity
AZOLI_p10511	COG1309	transcriptional regulator
AZOLI_p10513	COG1960	acyl-CoA dehydrogenase activity
AZOLI_p10514	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZOLI_p10514	COG1024	Enoyl-CoA hydratase
AZOLI_p10515	COG0318	PFAM AMP-dependent synthetase and ligase
AZOLI_p10516	COG1309	transcriptional regulator
AZOLI_p10520	COG1309	transcriptional regulator
AZOLI_p10521	COG1028	Short-chain dehydrogenase reductase Sdr
AZOLI_p10527	COG0469	pyruvate kinase activity
AZOLI_p10529	COG0546	phosphoglycolate phosphatase activity
AZOLI_p10532	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AZOLI_p10534	COG4208	sulfate ABC transporter
AZOLI_p10535	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AZOLI_p10549	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AZOLI_p10550	COG0367	asparagine synthase
AZOLI_p10551	COG0318	PFAM AMP-dependent synthetase and ligase
AZOLI_p10555	COG0438	transferase activity, transferring glycosyl groups
AZOLI_p10556	COG1215	transferase activity, transferring glycosyl groups
AZOLI_p10560	COG1045	serine acetyltransferase
AZOLI_p10561	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AZOLI_p10566	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AZOLI_p10567	COG0588	phosphoglycerate mutase activity
AZOLI_p10572	COG5002	protein histidine kinase activity
AZOLI_p10576	COG2089	acid synthase
AZOLI_p10577	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AZOLI_p10579	COG0508	dehydrogenase complex catalyzes the overall conversion of
AZOLI_p10579	COG0596	Alpha beta hydrolase
AZOLI_p10582	COG1028	Short-chain dehydrogenase reductase Sdr
AZOLI_p10583	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AZOLI_p10586	COG0457	Tetratricopeptide repeat
AZOLI_p10586	COG0859	PFAM glycosyl transferase family 9
AZOLI_p10590	COG0859	PFAM glycosyl transferase family 9
AZOLI_p10590	COG0457	Tetratricopeptide repeat
AZOLI_p10595	COG1558	bacterial-type flagellum-dependent cell motility
AZOLI_p10598	COG0366	Alpha amylase catalytic
AZOLI_p10599	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AZOLI_p10602	COG1749	Flagellar hook protein flgE
AZOLI_p10602	COG1749	Flagellar hook protein flgE
AZOLI_p10607	COG0737	Belongs to the 5'-nucleotidase family
AZOLI_p10611	COG0625	glutathione transferase activity
AZOLI_p10613	COG0318	PFAM AMP-dependent synthetase and ligase
AZOLI_p10615	COG0559	Belongs to the binding-protein-dependent transport system permease family
AZOLI_p10617	COG0411	ABC transporter
AZOLI_p10618	COG0410	ABC transporter
AZOLI_p10620	COG1024	Enoyl-CoA hydratase
AZOLI_p10622	COG0745	RESPONSE REGULATOR receiver
AZOLI_p10625	COG1640	4-alpha-glucanotransferase
AZOLI_p10629	COG4191	Histidine kinase
AZOLI_p10630	COG1301	dicarboxylic acid transport
AZOLI_p10633	COG0281	malic enzyme
AZOLI_p10633	COG0280	phosphate acetyltransferase
AZOLI_p10635	COG0859	PFAM glycosyl transferase family 9
AZOLI_p10635	COG0457	Tetratricopeptide repeat
AZOLI_p10640	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AZOLI_p10645	COG0559	Belongs to the binding-protein-dependent transport system permease family
AZOLI_p10647	COG0411	ABC transporter
AZOLI_p10648	COG2273	Hydrolase Family 16
AZOLI_p10649	COG0772	Belongs to the SEDS family
AZOLI_p10650	COG3706	GGDEF domain
AZOLI_p10651	COG1309	transcriptional regulator
AZOLI_p10655	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AZOLI_p10656	COG0393	Putative heavy-metal-binding
AZOLI_p10662	COG1280	lysine exporter protein (LysE YggA)
AZOLI_p10663	COG2183	response to ionizing radiation
AZOLI_p10668	COG3956	TIGRFAM MazG family protein
AZOLI_p10674	COG1012	belongs to the aldehyde dehydrogenase family
AZOLI_p10676	COG0183	Belongs to the thiolase family
AZOLI_p10677	COG1024	Enoyl-CoA hydratase
AZOLI_p10681	COG1028	Short-chain dehydrogenase reductase Sdr
AZOLI_p10687	COG3252	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT
AZOLI_p10688	COG0702	epimerase
AZOLI_p10691	COG1229	Formylmethanofuran dehydrogenase subunit A
AZOLI_p10692	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
AZOLI_p10696	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
AZOLI_p10699	COG0189	ligase activity
AZOLI_p10699	COG0569	domain protein
AZOLI_p10701	COG1131	(ABC) transporter
AZOLI_p10713	COG3383	formate dehydrogenase (NAD+) activity
AZOLI_p10715	COG0546	phosphoglycolate phosphatase activity
AZOLI_p10716	COG0191	fructose-bisphosphate aldolase activity
AZOLI_p10717	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AZOLI_p10719	COG3954	Phosphoribulokinase
AZOLI_p10720	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AZOLI_p10724	COG1850	ribulose-bisphosphate carboxylase activity
AZOLI_p10725	COG0583	DNA-binding transcription factor activity
AZOLI_p10728	COG0459	protein refolding
AZOLI_p10735	COG3474	cytochrome
AZOLI_p10751	COG0420	3'-5' exonuclease activity
AZOLI_p10755	COG0438	transferase activity, transferring glycosyl groups
AZOLI_p10763	COG0805	protein transport
AZOLI_p10764	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AZOLI_p10765	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AZOLI_p10766	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AZOLI_p10767	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AZOLI_p10768	COG1994	Peptidase M50
AZOLI_p10769	COG1472	Belongs to the glycosyl hydrolase 3 family
AZOLI_p10772	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AZOLI_p10773	COG0316	Belongs to the HesB IscA family
AZOLI_p10794	COG0582	viral genome integration into host DNA
AZOLI_p10806	COG0308	aminopeptidase N
AZOLI_p10810	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AZOLI_p10814	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AZOLI_p10818	COG0463	Glycosyl transferase, family 2
AZOLI_p10820	COG0740	serine-type endopeptidase activity
AZOLI_p10825	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AZOLI_p10834	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AZOLI_p10838	COG0583	DNA-binding transcription factor activity
AZOLI_p10842	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AZOLI_p10842	COG2070	2-Nitropropane dioxygenase
AZOLI_p10853	COG1760	l-serine dehydratase
AZOLI_p10855	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AZOLI_p10857	COG0446	pyridine nucleotide-disulphide oxidoreductase
AZOLI_p10857	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AZOLI_p10866	COG4175	Glycine betaine
AZOLI_p10867	COG2113	Glycine betaine
AZOLI_p10873	COG0446	pyridine nucleotide-disulphide oxidoreductase
AZOLI_p10873	COG1902	pentaerythritol trinitrate reductase activity
AZOLI_p10874	COG2181	nitrate reductase activity
AZOLI_p10874	COG0247	lactate metabolic process
AZOLI_p10877	COG4175	Glycine betaine
AZOLI_p10878	COG4176	ABC-type proline glycine betaine transport system permease component
AZOLI_p10882	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AZOLI_p10885	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AZOLI_p10886	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
AZOLI_p10888	COG0189	ligase activity
AZOLI_p10889	COG3252	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT
AZOLI_p10891	COG0702	epimerase
AZOLI_p10894	COG1229	Formylmethanofuran dehydrogenase subunit A
AZOLI_p10895	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
AZOLI_p10905	COG1891	lyase activity
AZOLI_p10914	COG4191	Histidine kinase
AZOLI_p10914	COG0784	Response regulator, receiver
AZOLI_p10915	COG2233	PERMEase
AZOLI_p10920	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZOLI_p10924	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AZOLI_p10926	COG1012	belongs to the aldehyde dehydrogenase family
AZOLI_p10929	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZOLI_p10931	COG0454	-acetyltransferase
AZOLI_p10935	COG0601	transmembrane transport
AZOLI_p10936	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZOLI_p10937	COG4172	Belongs to the ABC transporter superfamily
AZOLI_p10938	COG1522	sequence-specific DNA binding
AZOLI_p10939	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZOLI_p10940	COG0583	DNA-binding transcription factor activity
AZOLI_p10943	COG2354	Protein conserved in bacteria
AZOLI_p10948	COG4993	Dehydrogenase
AZOLI_p10949	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZOLI_p10950	COG2010	Cytochrome c
AZOLI_p10952	COG0714	Associated with various cellular activities
AZOLI_p10967	COG2814	Major facilitator Superfamily
AZOLI_p10974	COG0840	transmembrane signaling receptor activity
AZOLI_p10976	COG3485	protocatechuate 3,4-dioxygenase
AZOLI_p10980	COG0583	DNA-binding transcription factor activity
AZOLI_p10983	COG0154	amidase activity
AZOLI_p10986	COG4638	Rieske (2fe-2S)
AZOLI_p10990	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AZOLI_p10999	COG0559	Belongs to the binding-protein-dependent transport system permease family
AZOLI_p11003	COG3485	protocatechuate 3,4-dioxygenase
AZOLI_p11010	COG1252	NADH dehydrogenase
AZOLI_p11024	COG4638	Rieske (2fe-2S)
AZOLI_p11025	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AZOLI_p11026	COG2146	nitrite reductase [NAD(P)H] activity
AZOLI_p11031	COG1137	ATPase activity
AZOLI_p11034	COG4584	PFAM Integrase catalytic
AZOLI_p11035	COG1484	DNA-dependent DNA replication
AZOLI_p11042	COG2271	Major facilitator Superfamily
AZOLI_p11044	COG0583	DNA-binding transcription factor activity
AZOLI_p20005	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
AZOLI_p20006	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZOLI_p20007	COG0583	DNA-binding transcription factor activity
AZOLI_p20008	COG5383	Protein conserved in bacteria
AZOLI_p20009	COG3300	MHYT domain
AZOLI_p20009	COG5001	Diguanylate cyclase
AZOLI_p20042	COG1484	DNA-dependent DNA replication
AZOLI_p20043	COG4584	PFAM Integrase catalytic
AZOLI_p20046	COG1396	sequence-specific DNA binding
AZOLI_p20049	COG1476	TRANSCRIPTIONal
AZOLI_p20056	COG1192	Involved in chromosome partitioning
AZOLI_p20065	COG3451	type IV secretory pathway VirB4
AZOLI_p20110	COG2433	Pfam Transposase IS66
AZOLI_p20111	COG3436	PFAM IS66 Orf2 family protein
AZOLI_p20112	COG2963	transposase activity
AZOLI_p20152	COG1132	(ABC) transporter
AZOLI_p20153	COG1132	(ABC) transporter
AZOLI_p20154	COG1120	ATPase activity
AZOLI_p20155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AZOLI_p20157	COG4774	siderophore transport
AZOLI_p20159	COG1021	2,3-dihydroxybenzoate-AMP ligase
AZOLI_p20160	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AZOLI_p20160	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AZOLI_p20161	COG2226	methyltransferase
AZOLI_p20161	COG3433	isochorismatase activity
AZOLI_p20161	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AZOLI_p20164	COG1605	Chorismate mutase
AZOLI_p20164	COG0287	Prephenate dehydrogenase
AZOLI_p20166	COG0583	DNA-binding transcription factor activity
AZOLI_p20171	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZOLI_p20176	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AZOLI_p20177	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AZOLI_p20179	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AZOLI_p20180	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AZOLI_p20181	COG1609	Transcriptional regulator
AZOLI_p20183	COG3293	Transposase
AZOLI_p20185	COG2207	Transcriptional regulator
AZOLI_p20188	COG1566	PFAM secretion protein HlyD family protein
AZOLI_p20199	COG1840	ABC-type Fe3 transport system, periplasmic component
AZOLI_p20200	COG3842	ATPase activity
AZOLI_p20202	COG0583	DNA-binding transcription factor activity
AZOLI_p20203	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AZOLI_p20204	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AZOLI_p20211	COG5001	Diguanylate cyclase
AZOLI_p20212	COG0586	Pfam SNARE associated Golgi protein
AZOLI_p20221	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZOLI_p20223	COG1028	Short-chain dehydrogenase reductase Sdr
AZOLI_p20224	COG0546	phosphoglycolate phosphatase activity
AZOLI_p20225	COG1760	l-serine dehydratase
AZOLI_p20226	COG0814	amino acid
AZOLI_p20228	COG3275	phosphorelay sensor kinase activity
AZOLI_p20229	COG3279	Response regulator of the LytR AlgR family
AZOLI_p20231	COG0745	RESPONSE REGULATOR receiver
AZOLI_p20233	COG0861	Integral membrane protein TerC family
AZOLI_p20237	COG3181	Tripartite tricarboxylate transporter family receptor
AZOLI_p20248	COG3483	tryptophan 2,3-dioxygenase activity
AZOLI_p20250	COG1584	GPR1 FUN34 yaaH family protein
AZOLI_p20251	COG0583	DNA-binding transcription factor activity
AZOLI_p20252	COG1028	Short-chain dehydrogenase reductase Sdr
AZOLI_p20254	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AZOLI_p20258	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZOLI_p20259	COG1116	anion transmembrane transporter activity
AZOLI_p20264	COG1312	Catalyzes the dehydration of D-mannonate
AZOLI_p20265	COG0246	Mannitol dehydrogenase
AZOLI_p20268	COG0745	RESPONSE REGULATOR receiver
AZOLI_p20268	COG3706	GGDEF domain
AZOLI_p20269	COG1802	Transcriptional regulator
AZOLI_p20270	COG0154	amidase activity
AZOLI_p20273	COG1177	transmembrane transport
AZOLI_p20274	COG1176	ABC-type spermidine putrescine transport system, permease component I
AZOLI_p20275	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AZOLI_p20276	COG3842	ATPase activity
AZOLI_p20277	COG1984	allophanate hydrolase subunit 2
AZOLI_p20278	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AZOLI_p20283	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AZOLI_p20287	COG4172	Belongs to the ABC transporter superfamily
AZOLI_p20288	COG0747	negative chemotaxis
AZOLI_p20289	COG0601	transmembrane transport
AZOLI_p20290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZOLI_p20292	COG2362	D-Aminopeptidase
AZOLI_p20293	COG1446	asparaginase
AZOLI_p20305	COG0444	Belongs to the ABC transporter superfamily
AZOLI_p20308	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AZOLI_p20310	COG0601	transmembrane transport
AZOLI_p20317	COG4566	intracellular signal transduction
AZOLI_p20318	COG4191	Histidine kinase
AZOLI_p20320	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AZOLI_p20321	COG2111	Na H antiporter
AZOLI_p20321	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AZOLI_p20322	COG1006	Multisubunit Na H antiporter MnhC subunit
AZOLI_p20323	COG0651	ATP synthesis coupled electron transport
AZOLI_p20324	COG1863	multisubunit Na H antiporter MnhE subunit
AZOLI_p20325	COG2212	antiporter activity
AZOLI_p20326	COG1320	monovalent cation:proton antiporter activity
AZOLI_p20329	COG0455	bacterial-type flagellum organization
AZOLI_p20331	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AZOLI_p20332	COG2204	response regulator
AZOLI_p20333	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AZOLI_p20334	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AZOLI_p20336	COG1766	The M ring may be actively involved in energy transduction
AZOLI_p20337	COG1396	sequence-specific DNA binding
AZOLI_p20339	COG2198	Histidine kinase
AZOLI_p20339	COG2205	protein histidine kinase activity
AZOLI_p20339	COG0784	Response regulator, receiver
AZOLI_p20342	COG1253	flavin adenine dinucleotide binding
AZOLI_p20345	COG0784	Response regulator, receiver
AZOLI_p20345	COG2198	Histidine kinase
AZOLI_p20345	COG5002	protein histidine kinase activity
AZOLI_p20350	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AZOLI_p20351	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AZOLI_p20352	COG2080	2 iron, 2 sulfur cluster binding
AZOLI_p20353	COG3791	Glutathione-dependent formaldehyde-activating
AZOLI_p20355	COG0028	Belongs to the TPP enzyme family
AZOLI_p20357	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AZOLI_p20358	COG0367	asparagine synthase
AZOLI_p20360	COG1363	Peptidase, m42
AZOLI_p20361	COG5002	protein histidine kinase activity
AZOLI_p20361	COG0784	Response regulator, receiver
AZOLI_p20362	COG0745	RESPONSE REGULATOR receiver
AZOLI_p20363	COG2201	protein-glutamate methylesterase activity
AZOLI_p20368	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AZOLI_p20370	COG1012	belongs to the aldehyde dehydrogenase family
AZOLI_p20370	COG2030	dehydratase
AZOLI_p20379	COG1304	FMN binding
AZOLI_p20381	COG3707	response regulator
AZOLI_p20383	COG1846	Transcriptional regulator
AZOLI_p20384	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AZOLI_p20386	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZOLI_p20392	COG2226	methyltransferase
AZOLI_p20400	COG2169	Transcriptional regulator
AZOLI_p20400	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AZOLI_p20403	COG1131	(ABC) transporter
AZOLI_p20418	COG2847	Copper chaperone PCu(A)C
AZOLI_p20421	COG0784	Response regulator, receiver
AZOLI_p20422	COG3920	Histidine kinase
AZOLI_p20422	COG2202	Pas domain
AZOLI_p20423	COG0784	Response regulator, receiver
AZOLI_p20424	COG4251	negative regulation of phosphorylation
AZOLI_p20427	COG0697	spore germination
AZOLI_p20429	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZOLI_p20430	COG2010	Cytochrome c
AZOLI_p20430	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AZOLI_p20431	COG2080	2 iron, 2 sulfur cluster binding
AZOLI_p20432	COG1846	Transcriptional regulator
AZOLI_p20433	COG2309	aminopeptidase activity
AZOLI_p20435	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AZOLI_p20436	COG0596	Alpha beta hydrolase
AZOLI_p20437	COG3473	Maleate cis-trans isomerase
AZOLI_p20438	COG1335	isochorismatase
AZOLI_p20440	COG2271	Major facilitator Superfamily
AZOLI_p20441	COG0840	transmembrane signaling receptor activity
AZOLI_p20443	COG2814	Major facilitator Superfamily
AZOLI_p20445	COG0318	PFAM AMP-dependent synthetase and ligase
AZOLI_p20447	COG0583	DNA-binding transcription factor activity
AZOLI_p20451	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AZOLI_p20452	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AZOLI_p20453	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AZOLI_p20454	COG0842	Transport permease protein
AZOLI_p20455	COG1131	(ABC) transporter
AZOLI_p20457	COG2116	formate transmembrane transporter activity
AZOLI_p20459	COG0148	phosphopyruvate hydratase activity
AZOLI_p20461	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AZOLI_p20471	COG0252	asparaginase activity
AZOLI_p20474	COG2819	hydrolase of the alpha beta superfamily
AZOLI_p20475	COG4604	ABC transporter, ATP-binding protein
AZOLI_p20476	COG4605	iron ion homeostasis
AZOLI_p20477	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AZOLI_p20478	COG4607	ABC-type enterochelin transport system periplasmic component
AZOLI_p20481	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AZOLI_p20482	COG4774	siderophore transport
AZOLI_p20483	COG3128	pkhd-type hydroxylase
AZOLI_p20489	COG1414	Transcriptional regulator
AZOLI_p20493	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AZOLI_p20494	COG0066	3-isopropylmalate dehydratase activity
AZOLI_p20497	COG0559	Belongs to the binding-protein-dependent transport system permease family
AZOLI_p20500	COG0410	ABC transporter
AZOLI_p20503	COG4774	siderophore transport
AZOLI_p20504	COG1120	ATPase activity
AZOLI_p20506	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AZOLI_p20507	COG1132	(ABC) transporter
AZOLI_p20511	COG0840	transmembrane signaling receptor activity
AZOLI_p20511	COG3290	protein histidine kinase activity
AZOLI_p20514	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AZOLI_p20515	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AZOLI_p20516	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AZOLI_p20517	COG2205	protein histidine kinase activity
AZOLI_p20518	COG0745	RESPONSE REGULATOR receiver
AZOLI_p20526	COG0348	domain, Protein
AZOLI_p20527	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZOLI_p20528	COG0649	NAD binding
AZOLI_p20529	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AZOLI_p20531	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AZOLI_p20532	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AZOLI_p20533	COG0651	ATP synthesis coupled electron transport
AZOLI_p20536	COG2414	aldehyde ferredoxin oxidoreductase
AZOLI_p20540	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AZOLI_p20543	COG1028	Short-chain dehydrogenase reductase Sdr
AZOLI_p20544	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
AZOLI_p20546	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AZOLI_p20547	COG0840	transmembrane signaling receptor activity
AZOLI_p20549	COG2267	carboxylic ester hydrolase activity
AZOLI_p20554	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AZOLI_p20554	COG1918	ferrous iron import across plasma membrane
AZOLI_p20556	COG1321	iron dependent repressor
AZOLI_p20557	COG1914	H( )-stimulated, divalent metal cation uptake system
AZOLI_p20558	COG3622	Belongs to the hyi family
AZOLI_p20559	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AZOLI_p20560	COG1522	sequence-specific DNA binding
AZOLI_p20565	COG0581	inorganic phosphate transmembrane transporter activity
AZOLI_p20566	COG1176	ABC-type spermidine putrescine transport system, permease component I
AZOLI_p20568	COG3842	ATPase activity
AZOLI_p20570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AZOLI_p20570	COG1263	PTS System
AZOLI_p20571	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AZOLI_p20574	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AZOLI_p20575	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AZOLI_p20578	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AZOLI_p20578	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AZOLI_p20583	COG0840	transmembrane signaling receptor activity
AZOLI_p20584	COG1940	carbohydrate kinase activity
AZOLI_p20585	COG1129	ABC transporter
AZOLI_p20586	COG1172	Belongs to the binding-protein-dependent transport system permease family
AZOLI_p20587	COG1879	ABC-type sugar transport system periplasmic component
AZOLI_p20589	COG0673	inositol 2-dehydrogenase activity
AZOLI_p20591	COG1335	isochorismatase
AZOLI_p20593	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AZOLI_p20595	COG4566	intracellular signal transduction
AZOLI_p20596	COG4191	Histidine kinase
AZOLI_p20598	COG4566	intracellular signal transduction
AZOLI_p20599	COG1595	DNA-templated transcription, initiation
AZOLI_p20605	COG4264	IucA IucC family
AZOLI_p20608	COG1082	Xylose isomerase domain protein TIM barrel
AZOLI_p20619	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AZOLI_p20621	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AZOLI_p20624	COG4566	intracellular signal transduction
AZOLI_p20625	COG4191	Histidine kinase
AZOLI_p20626	COG4977	sequence-specific DNA binding
AZOLI_p20632	COG3706	GGDEF domain
AZOLI_p20633	COG1522	sequence-specific DNA binding
AZOLI_p20635	COG1349	DNA-binding transcription factor activity
AZOLI_p20637	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AZOLI_p20638	COG1879	ABC-type sugar transport system periplasmic component
AZOLI_p20639	COG1129	ABC transporter
AZOLI_p20640	COG1172	Belongs to the binding-protein-dependent transport system permease family
AZOLI_p20641	COG1172	Belongs to the binding-protein-dependent transport system permease family
AZOLI_p20643	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AZOLI_p20645	COG2814	Major facilitator Superfamily
AZOLI_p20648	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AZOLI_p20654	COG0861	Integral membrane protein TerC family
AZOLI_p20658	COG4221	oxidoreductase activity
AZOLI_p20659	COG1177	transmembrane transport
AZOLI_p20660	COG1176	ABC-type spermidine putrescine transport system, permease component I
AZOLI_p20669	COG0251	oxidation-reduction process
AZOLI_p20671	COG0251	oxidation-reduction process
AZOLI_p20674	COG3721	Heme iron utilization protein
AZOLI_p20675	COG2205	protein histidine kinase activity
AZOLI_p20677	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AZOLI_p20678	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AZOLI_p20679	COG4558	Periplasmic binding protein
AZOLI_p20680	COG3720	iron ion transport
AZOLI_p20682	COG0601	transmembrane transport
AZOLI_p20683	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZOLI_p20684	COG4172	Belongs to the ABC transporter superfamily
AZOLI_p20685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZOLI_p20686	COG0765	amino acid transport
AZOLI_p20687	COG1126	abc transporter atp-binding protein
AZOLI_p20688	COG1454	alcohol dehydrogenase
AZOLI_p20688	COG1012	belongs to the aldehyde dehydrogenase family
AZOLI_p20689	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AZOLI_p20691	COG4566	intracellular signal transduction
AZOLI_p20692	COG4191	Histidine kinase
AZOLI_p20695	COG4626	Terminase
AZOLI_p20695	COG1802	Transcriptional regulator
AZOLI_p20699	COG4214	carbohydrate transport
AZOLI_p20700	COG4213	ABC transporter substrate-binding protein
AZOLI_p20701	COG2115	Belongs to the xylose isomerase family
AZOLI_p20702	COG1070	Carbohydrate kinase
AZOLI_p20703	COG1609	Transcriptional regulator
AZOLI_p20707	COG2353	YceI-like domain
AZOLI_p20712	COG1028	Short-chain dehydrogenase reductase Sdr
AZOLI_p20713	COG1172	Belongs to the binding-protein-dependent transport system permease family
AZOLI_p20714	COG1129	ABC transporter
AZOLI_p20715	COG1879	ABC-type sugar transport system periplasmic component
AZOLI_p20716	COG1984	allophanate hydrolase subunit 2
AZOLI_p20718	COG0439	Biotin carboxylase
AZOLI_p20719	COG0511	ligase activity, forming carbon-carbon bonds
AZOLI_p20720	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AZOLI_p20728	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AZOLI_p20731	COG4263	nitrous-oxide reductase activity
AZOLI_p20735	COG1404	Belongs to the peptidase S8 family
AZOLI_p20738	COG3062	negative regulation of establishment of protein localization
AZOLI_p20741	COG3005	denitrification pathway
AZOLI_p20742	COG1475	DNA binding
AZOLI_p20743	COG1192	Involved in chromosome partitioning
AZOLI_p20745	COG1278	Cold shock
AZOLI_p20747	COG1192	Involved in chromosome partitioning
AZOLI_p30004	COG3273	potassium ion transport
AZOLI_p30004	COG0471	metal ion transport
AZOLI_p30005	COG0517	IMP dehydrogenase activity
AZOLI_p30007	COG0784	Response regulator, receiver
AZOLI_p30008	COG2205	protein histidine kinase activity
AZOLI_p30008	COG0784	Response regulator, receiver
AZOLI_p30009	COG1758	RNA polymerase activity
AZOLI_p30011	COG1132	(ABC) transporter
AZOLI_p30017	COG0375	protein maturation
AZOLI_p30019	COG2116	formate transmembrane transporter activity
AZOLI_p30020	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AZOLI_p30022	COG3260	NADH ubiquinone oxidoreductase 20
AZOLI_p30024	COG3261	NADH dehydrogenase
AZOLI_p30024	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AZOLI_p30025	COG0651	ATP synthesis coupled electron transport
AZOLI_p30026	COG4237	Hydrogenase 4 membrane
AZOLI_p30027	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AZOLI_p30028	COG0650	Formate hydrogenlyase subunit 4
AZOLI_p30029	COG0651	ATP synthesis coupled electron transport
AZOLI_p30030	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AZOLI_p30032	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AZOLI_p30033	COG3383	formate dehydrogenase (NAD+) activity
AZOLI_p30036	COG0583	DNA-binding transcription factor activity
AZOLI_p30043	COG1301	dicarboxylic acid transport
AZOLI_p30044	COG1027	Aspartate ammonia-lyase
AZOLI_p30045	COG1982	Orn Lys Arg decarboxylase major
AZOLI_p30047	COG2258	MOSC domain
AZOLI_p30050	COG1566	PFAM secretion protein HlyD family protein
AZOLI_p30051	COG1289	transmembrane transporter activity
AZOLI_p30053	COG3852	Histidine kinase
AZOLI_p30065	COG0375	protein maturation
AZOLI_p30066	COG2204	response regulator
AZOLI_p30070	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
AZOLI_p30071	COG4106	trans-aconitate 2-methyltransferase activity
AZOLI_p30072	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AZOLI_p30074	COG0659	secondary active sulfate transmembrane transporter activity
AZOLI_p30076	COG1755	Isoprenylcysteine carboxyl methyltransferase
AZOLI_p30077	COG1028	Short-chain dehydrogenase reductase Sdr
AZOLI_p30080	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AZOLI_p30081	COG2852	Protein conserved in bacteria
AZOLI_p30083	COG0521	Mo-molybdopterin cofactor biosynthetic process
AZOLI_p30085	COG0714	Associated with various cellular activities
AZOLI_p30086	COG3256	nitric oxide reductase
AZOLI_p30089	COG1845	cytochrome c oxidase, subunit III
AZOLI_p30092	COG1448	Aminotransferase
AZOLI_p30094	COG3012	SEC-C Motif Domain Protein
AZOLI_p30095	COG3293	Transposase
AZOLI_p30098	COG3437	response regulator, receiver
AZOLI_p30098	COG2770	Histidine kinase
AZOLI_p30115	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AZOLI_p30116	COG4191	Histidine kinase
AZOLI_p30117	COG0747	negative chemotaxis
AZOLI_p30118	COG3437	response regulator, receiver
AZOLI_p30118	COG0784	Response regulator, receiver
AZOLI_p30120	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AZOLI_p30126	COG0737	Belongs to the 5'-nucleotidase family
AZOLI_p30127	COG0505	Belongs to the CarA family
AZOLI_p30128	COG2068	MobA-Related Protein
AZOLI_p30130	COG1309	transcriptional regulator
AZOLI_p30131	COG4176	ABC-type proline glycine betaine transport system permease component
AZOLI_p30136	COG3180	Ammonia monooxygenase
AZOLI_p30138	COG3487	Iron-regulated protein
AZOLI_p30139	COG2132	Multicopper oxidase
AZOLI_p30143	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AZOLI_p30144	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AZOLI_p30145	COG0583	DNA-binding transcription factor activity
AZOLI_p30148	COG3008	intermembrane lipid transfer
AZOLI_p30148	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AZOLI_p30149	COG2995	paraquat-inducible protein a
AZOLI_p30150	COG2188	Transcriptional regulator
AZOLI_p30152	COG0765	amino acid transport
AZOLI_p30154	COG1126	abc transporter atp-binding protein
AZOLI_p30155	COG4115	mRNA cleavage
AZOLI_p30156	COG2161	toxin-antitoxin pair type II binding
AZOLI_p30157	COG1122	ATPase activity
AZOLI_p30158	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AZOLI_p30159	COG1268	BioY protein
AZOLI_p30160	COG0318	PFAM AMP-dependent synthetase and ligase
AZOLI_p30161	COG0183	Belongs to the thiolase family
AZOLI_p30165	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AZOLI_p30171	COG5002	protein histidine kinase activity
AZOLI_p30171	COG0784	Response regulator, receiver
AZOLI_p30173	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AZOLI_p30174	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AZOLI_p30178	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AZOLI_p30182	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AZOLI_p30184	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AZOLI_p30187	COG0123	including yeast histone deacetylase and acetoin utilization protein
AZOLI_p30190	COG0640	Transcriptional regulator
AZOLI_p30191	COG2363	Small membrane protein
AZOLI_p30194	COG0154	amidase activity
AZOLI_p30200	COG5001	Diguanylate cyclase
AZOLI_p30200	COG5002	protein histidine kinase activity
AZOLI_p30202	COG2116	formate transmembrane transporter activity
AZOLI_p30206	COG1131	(ABC) transporter
AZOLI_p30209	COG0366	Alpha amylase catalytic
AZOLI_p30211	COG1794	racemase activity, acting on amino acids and derivatives
AZOLI_p30215	COG2197	response regulator
AZOLI_p30218	COG5002	protein histidine kinase activity
AZOLI_p30218	COG0784	Response regulator, receiver
AZOLI_p30218	COG2205	protein histidine kinase activity
AZOLI_p30221	COG2201	protein-glutamate methylesterase activity
AZOLI_p30225	COG4325	translation initiation factor activity
AZOLI_p30229	COG2323	membrane
AZOLI_p30234	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AZOLI_p30236	COG0704	Plays a role in the regulation of phosphate uptake
AZOLI_p30238	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AZOLI_p30239	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AZOLI_p30241	COG1959	2 iron, 2 sulfur cluster binding
AZOLI_p30242	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZOLI_p30243	COG1475	DNA binding
AZOLI_p30245	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AZOLI_p30253	COG0719	Fe-S assembly protein
AZOLI_p30254	COG2827	Endonuclease containing a URI domain
AZOLI_p30255	COG0396	ATPase activity
AZOLI_p30256	COG0719	Fe-S assembly protein
AZOLI_p30257	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AZOLI_p30258	COG0822	iron-sulfur transferase activity
AZOLI_p30259	COG2151	metal-sulfur cluster biosynthetic enzyme
AZOLI_p30260	COG0316	Belongs to the HesB IscA family
AZOLI_p30267	COG1741	Belongs to the pirin family
AZOLI_p30273	COG0800	Aldolase
AZOLI_p30277	COG1028	Short-chain dehydrogenase reductase Sdr
AZOLI_p30283	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AZOLI_p30286	COG0535	radical SAM domain protein
AZOLI_p30287	COG0010	Belongs to the arginase family
AZOLI_p30288	COG1737	Transcriptional regulator
AZOLI_p30288	COG0837	glucose binding
AZOLI_p30290	COG1882	Formate acetyltransferase
AZOLI_p30291	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AZOLI_p30294	COG1609	Transcriptional regulator
AZOLI_p30296	COG0246	Mannitol dehydrogenase
AZOLI_p30297	COG1013	pyruvate-flavodoxin oxidoreductase activity
AZOLI_p30297	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AZOLI_p30297	COG0674	pyruvate-flavodoxin oxidoreductase activity
AZOLI_p30300	COG2271	Major facilitator Superfamily
AZOLI_p30306	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZOLI_p30313	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AZOLI_p30313	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AZOLI_p30320	COG5002	protein histidine kinase activity
AZOLI_p30321	COG0745	RESPONSE REGULATOR receiver
AZOLI_p30321	COG3706	GGDEF domain
AZOLI_p30327	COG3083	sulfuric ester hydrolase activity
AZOLI_p30328	COG1177	transmembrane transport
AZOLI_p30329	COG1176	ABC-type spermidine putrescine transport system, permease component I
AZOLI_p30330	COG3842	ATPase activity
AZOLI_p30332	COG0535	radical SAM domain protein
AZOLI_p30338	COG2076	Multidrug Resistance protein
AZOLI_p30339	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AZOLI_p30339	COG0546	phosphoglycolate phosphatase activity
AZOLI_p30340	COG0174	glutamine synthetase
AZOLI_p30341	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZOLI_p30343	COG1196	nuclear chromosome segregation
AZOLI_p30344	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AZOLI_p30352	COG3047	cAMP biosynthetic process
AZOLI_p30353	COG0516	GMP reductase activity
AZOLI_p30353	COG0517	IMP dehydrogenase activity
AZOLI_p30354	COG2197	response regulator
AZOLI_p30355	COG1960	acyl-CoA dehydrogenase activity
AZOLI_p30356	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZOLI_p30356	COG1024	Enoyl-CoA hydratase
AZOLI_p30357	COG0183	Belongs to the thiolase family
AZOLI_p30360	COG2373	Large extracellular alpha-helical protein
AZOLI_p30375	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AZOLI_p30376	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AZOLI_p30377	COG1012	belongs to the aldehyde dehydrogenase family
AZOLI_p30378	COG1917	Cupin 2, conserved barrel domain protein
AZOLI_p30378	COG1396	sequence-specific DNA binding
AZOLI_p30380	COG1176	ABC-type spermidine putrescine transport system, permease component I
AZOLI_p30381	COG2182	Extracellular solute-binding protein
AZOLI_p30382	COG3842	ATPase activity
AZOLI_p30383	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AZOLI_p30386	COG0583	DNA-binding transcription factor activity
AZOLI_p30395	COG0583	DNA-binding transcription factor activity
AZOLI_p30396	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AZOLI_p30397	COG0235	Class ii aldolase
AZOLI_p30399	COG0601	transmembrane transport
AZOLI_p30401	COG4172	Belongs to the ABC transporter superfamily
AZOLI_p30402	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AZOLI_p30405	COG0697	spore germination
AZOLI_p30407	COG2723	6-phospho-beta-galactosidase activity
AZOLI_p30418	COG3293	Transposase
AZOLI_p30425	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AZOLI_p30428	COG1215	transferase activity, transferring glycosyl groups
AZOLI_p30435	COG0795	lipopolysaccharide-transporting ATPase activity
AZOLI_p30438	COG1104	cysteine desulfurase activity
AZOLI_p30441	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AZOLI_p30450	COG2986	histidine ammonia-lyase
AZOLI_p30451	COG0402	S-adenosylhomocysteine deaminase activity
AZOLI_p30452	COG1228	amidohydrolase
AZOLI_p30453	COG2188	Transcriptional regulator
AZOLI_p30455	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AZOLI_p30459	COG1028	Short-chain dehydrogenase reductase Sdr
AZOLI_p30461	COG0542	response to heat
AZOLI_p30466	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AZOLI_p30466	COG2885	chlorophyll binding
AZOLI_p30472	COG0697	spore germination
AZOLI_p30482	COG1360	Flagellar Motor Protein
AZOLI_p30485	COG3501	Rhs element vgr protein
AZOLI_p30490	COG2267	carboxylic ester hydrolase activity
AZOLI_p30492	COG0583	DNA-binding transcription factor activity
AZOLI_p30493	COG0655	NAD(P)H dehydrogenase (quinone) activity
AZOLI_p30494	COG0435	Glutathione S-transferase
AZOLI_p30502	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AZOLI_p30504	COG3706	GGDEF domain
AZOLI_p30510	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AZOLI_p30511	COG0408	coproporphyrinogen oxidase activity
AZOLI_p30515	COG1271	oxidase subunit
AZOLI_p30516	COG1294	oxidase, subunit
AZOLI_p30519	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AZOLI_p30521	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AZOLI_p30522	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AZOLI_p30523	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AZOLI_p30525	COG0356	it plays a direct role in the translocation of protons across the membrane
AZOLI_p30529	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AZOLI_p30531	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AZOLI_p30533	COG1012	belongs to the aldehyde dehydrogenase family
AZOLI_p30534	COG0028	Belongs to the TPP enzyme family
AZOLI_p30536	COG1215	transferase activity, transferring glycosyl groups
AZOLI_p30537	COG4178	(ABC) transporter
AZOLI_p30542	COG0438	transferase activity, transferring glycosyl groups
AZOLI_p30545	COG0438	transferase activity, transferring glycosyl groups
AZOLI_p30549	COG0489	protein tyrosine kinase activity
AZOLI_p30549	COG3206	protein involved in exopolysaccharide biosynthesis
AZOLI_p30556	COG1609	Transcriptional regulator
AZOLI_p30557	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AZOLI_p30557	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AZOLI_p30558	COG1105	Belongs to the carbohydrate kinase PfkB family
AZOLI_p30559	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AZOLI_p30559	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AZOLI_p30561	COG0457	Tetratricopeptide repeat
AZOLI_p30561	COG0859	PFAM glycosyl transferase family 9
AZOLI_p30566	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AZOLI_p30575	COG1024	Enoyl-CoA hydratase
AZOLI_p30575	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZOLI_p30576	COG2010	Cytochrome c
AZOLI_p30577	COG0022	dehydrogenase e1 component
AZOLI_p30578	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AZOLI_p30579	COG1174	glycine betaine transport
AZOLI_p30580	COG1125	glycine betaine transport
AZOLI_p30581	COG1174	glycine betaine transport
AZOLI_p30582	COG1732	Glycine betaine
AZOLI_p30584	COG1335	isochorismatase
AZOLI_p30587	COG0535	radical SAM domain protein
AZOLI_p30588	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
AZOLI_p30596	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AZOLI_p40003	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AZOLI_p40006	COG2814	Major facilitator Superfamily
AZOLI_p40012	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZOLI_p40013	COG4597	amino acid ABC transporter
AZOLI_p40014	COG0765	amino acid transport
AZOLI_p40015	COG1126	abc transporter atp-binding protein
AZOLI_p40018	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZOLI_p40023	COG0683	leucine binding
AZOLI_p40024	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AZOLI_p40025	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AZOLI_p40026	COG0183	Belongs to the thiolase family
AZOLI_p40027	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AZOLI_p40028	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AZOLI_p40030	COG3485	protocatechuate 3,4-dioxygenase
AZOLI_p40031	COG3485	protocatechuate 3,4-dioxygenase
AZOLI_p40032	COG0840	transmembrane signaling receptor activity
AZOLI_p40037	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AZOLI_p40038	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AZOLI_p40040	COG3265	gluconokinase activity
AZOLI_p40043	COG1609	Transcriptional regulator
AZOLI_p40044	COG0840	transmembrane signaling receptor activity
AZOLI_p40045	COG1028	Short-chain dehydrogenase reductase Sdr
AZOLI_p40046	COG0116	Belongs to the methyltransferase superfamily
AZOLI_p40046	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AZOLI_p40053	COG0564	pseudouridine synthase activity
AZOLI_p40055	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AZOLI_p40056	COG0454	-acetyltransferase
AZOLI_p40063	COG2814	Major facilitator Superfamily
AZOLI_p40064	COG0583	DNA-binding transcription factor activity
AZOLI_p40065	COG0667	Aldo Keto reductase
AZOLI_p40066	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AZOLI_p40067	COG1192	Involved in chromosome partitioning
AZOLI_p40070	COG1393	Belongs to the ArsC family
AZOLI_p40071	COG0798	PFAM Bile acid sodium symporter
AZOLI_p40072	COG0431	NADPH-dependent FMN reductase
AZOLI_p40074	COG1960	acyl-CoA dehydrogenase activity
AZOLI_p40081	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AZOLI_p40087	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZOLI_p40092	COG0438	transferase activity, transferring glycosyl groups
AZOLI_p40093	COG0588	phosphoglycerate mutase activity
AZOLI_p40099	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AZOLI_p40100	COG1126	abc transporter atp-binding protein
AZOLI_p40101	COG0765	amino acid transport
AZOLI_p40102	COG0765	amino acid transport
AZOLI_p40104	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZOLI_p40112	COG0667	Aldo Keto reductase
AZOLI_p40113	COG2814	Major facilitator Superfamily
AZOLI_p40114	COG0583	DNA-binding transcription factor activity
AZOLI_p40124	COG0318	PFAM AMP-dependent synthetase and ligase
AZOLI_p40124	COG0204	Acyl-transferase
AZOLI_p40125	COG2884	Cell division ATP-binding protein ftsE
AZOLI_p40129	COG2217	Heavy metal translocating P-type atpase
AZOLI_p40131	COG2610	gluconate transmembrane transporter activity
AZOLI_p40132	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AZOLI_p40133	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AZOLI_p40134	COG1028	Short-chain dehydrogenase reductase Sdr
AZOLI_p40145	COG3293	Transposase
AZOLI_p40146	COG1672	PFAM Archaeal ATPase
AZOLI_p40146	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AZOLI_p40147	COG0129	dihydroxy-acid dehydratase activity
AZOLI_p40158	COG0583	DNA-binding transcription factor activity
AZOLI_p40161	COG0564	pseudouridine synthase activity
AZOLI_p40164	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AZOLI_p40166	COG0842	Transport permease protein
AZOLI_p40167	COG0842	Transport permease protein
AZOLI_p40167	COG1129	ABC transporter
AZOLI_p40168	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZOLI_p40176	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AZOLI_p40177	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AZOLI_p40178	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZOLI_p40180	COG0668	transmembrane transport
AZOLI_p40181	COG1802	Transcriptional regulator
AZOLI_p40183	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AZOLI_p40188	COG0840	transmembrane signaling receptor activity
AZOLI_p40191	COG0411	ABC transporter
AZOLI_p40196	COG0686	Belongs to the AlaDH PNT family
AZOLI_p40198	COG1522	sequence-specific DNA binding
AZOLI_p40200	COG0583	DNA-binding transcription factor activity
AZOLI_p40201	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AZOLI_p40205	COG0784	Response regulator, receiver
AZOLI_p40205	COG2198	Histidine kinase
AZOLI_p40205	COG2205	protein histidine kinase activity
AZOLI_p40210	COG2205	protein histidine kinase activity
AZOLI_p40210	COG2202	Pas domain
AZOLI_p40212	COG0306	phosphate transporter
AZOLI_p40219	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AZOLI_p40220	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AZOLI_p40220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AZOLI_p40223	COG0667	Aldo Keto reductase
AZOLI_p40225	COG2084	Dehydrogenase
AZOLI_p40227	COG3622	Belongs to the hyi family
AZOLI_p40229	COG0446	pyridine nucleotide-disulphide oxidoreductase
AZOLI_p40229	COG1902	pentaerythritol trinitrate reductase activity
AZOLI_p40230	COG1802	Transcriptional regulator
AZOLI_p40231	COG0673	inositol 2-dehydrogenase activity
AZOLI_p40232	COG0861	Integral membrane protein TerC family
AZOLI_p40233	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AZOLI_p40235	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AZOLI_p40236	COG0778	Nitroreductase
AZOLI_p40237	COG1797	cobyrinic acid a,c-diamide synthase activity
AZOLI_p40243	COG2099	Precorrin-6x reductase
AZOLI_p40259	COG2050	protein possibly involved in aromatic compounds catabolism
AZOLI_p40260	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZOLI_p40261	COG1024	Enoyl-CoA hydratase
AZOLI_p40262	COG1012	belongs to the aldehyde dehydrogenase family
AZOLI_p40263	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AZOLI_p40264	COG2151	metal-sulfur cluster biosynthetic enzyme
AZOLI_p40265	COG3396	Phenylacetate-CoA oxygenase
AZOLI_p40266	COG3460	Phenylacetate-CoA oxygenase
AZOLI_p40267	COG3396	Phenylacetate-CoA oxygenase
AZOLI_p40269	COG5002	protein histidine kinase activity
AZOLI_p40271	COG1764	response to oxidative stress
AZOLI_p40276	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AZOLI_p40286	COG0583	DNA-binding transcription factor activity
AZOLI_p40287	COG4948	Mandelate Racemase Muconate Lactonizing
AZOLI_p40291	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AZOLI_p40297	COG3383	formate dehydrogenase (NAD+) activity
AZOLI_p40297	COG0243	molybdopterin cofactor binding
AZOLI_p40298	COG0437	4 iron, 4 sulfur cluster binding
AZOLI_p40299	COG2864	formate dehydrogenase
AZOLI_p40300	COG1012	belongs to the aldehyde dehydrogenase family
AZOLI_p40303	COG2202	Pas domain
AZOLI_p40303	COG2205	protein histidine kinase activity
AZOLI_p40309	COG0427	acetyl-CoA hydrolase
AZOLI_p40311	COG1280	lysine exporter protein (LysE YggA)
AZOLI_p40316	COG4303	Ethanolamine ammonia lyase large subunit
AZOLI_p40318	COG0531	amino acid
AZOLI_p40322	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AZOLI_p40326	COG1278	Cold shock
AZOLI_p40327	COG3012	SEC-C Motif Domain Protein
AZOLI_p40329	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AZOLI_p40333	COG0671	phosphoesterase, PA-phosphatase related
AZOLI_p40335	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AZOLI_p40337	COG0793	Belongs to the peptidase S41A family
AZOLI_p40346	COG1295	ribonuclease BN
AZOLI_p40351	COG2723	6-phospho-beta-galactosidase activity
AZOLI_p40353	COG2233	PERMEase
AZOLI_p40354	COG3293	Transposase
AZOLI_p40359	COG0586	Pfam SNARE associated Golgi protein
AZOLI_p40360	COG1522	sequence-specific DNA binding
AZOLI_p40361	COG3214	Protein conserved in bacteria
AZOLI_p40363	COG0784	Response regulator, receiver
AZOLI_p40369	COG0402	S-adenosylhomocysteine deaminase activity
AZOLI_p40370	COG1971	Probably functions as a manganese efflux pump
AZOLI_p40372	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AZOLI_p40374	COG1131	(ABC) transporter
AZOLI_p40382	COG0489	protein tyrosine kinase activity
AZOLI_p40382	COG3206	protein involved in exopolysaccharide biosynthesis
AZOLI_p40385	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AZOLI_p40387	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AZOLI_p40390	COG0438	transferase activity, transferring glycosyl groups
AZOLI_p40391	COG1522	sequence-specific DNA binding
AZOLI_p40395	COG0628	permease
AZOLI_p40406	COG0848	biopolymer transport protein
AZOLI_p40410	COG4221	oxidoreductase activity
AZOLI_p40413	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AZOLI_p40415	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
AZOLI_p40416	COG1595	DNA-templated transcription, initiation
AZOLI_p40417	COG3806	Anti-sigma factor
AZOLI_p40425	COG2204	response regulator
AZOLI_p40429	COG0405	Gamma-glutamyltransferase
AZOLI_p40433	COG0587	DNA-directed DNA polymerase activity
AZOLI_p40435	COG1157	protein secretion by the type III secretion system
AZOLI_p40436	COG0745	RESPONSE REGULATOR receiver
AZOLI_p40437	COG1278	Cold shock
AZOLI_p40442	COG0745	RESPONSE REGULATOR receiver
AZOLI_p40443	COG0835	chemotaxis
AZOLI_p40444	COG0643	Histidine kinase
AZOLI_p40444	COG2198	Histidine kinase
AZOLI_p40449	COG2205	protein histidine kinase activity
AZOLI_p40452	COG3920	Histidine kinase
AZOLI_p40454	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AZOLI_p40458	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AZOLI_p40459	COG0583	DNA-binding transcription factor activity
AZOLI_p40461	COG2197	response regulator
AZOLI_p40463	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AZOLI_p40464	COG0330	HflC and HflK could
AZOLI_p40465	COG0330	HflC and HflK could
AZOLI_p40466	COG0489	protein tyrosine kinase activity
AZOLI_p40467	COG0443	Heat shock 70 kDa protein
AZOLI_p40468	COG1028	Short-chain dehydrogenase reductase Sdr
AZOLI_p40473	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AZOLI_p40475	COG5002	protein histidine kinase activity
AZOLI_p40475	COG2205	protein histidine kinase activity
AZOLI_p40475	COG0784	Response regulator, receiver
AZOLI_p40477	COG0745	RESPONSE REGULATOR receiver
AZOLI_p40477	COG3706	GGDEF domain
AZOLI_p40483	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AZOLI_p40485	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AZOLI_p40486	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZOLI_p40487	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZOLI_p40490	COG1802	Transcriptional regulator
AZOLI_p40491	COG1803	Methylglyoxal synthase
AZOLI_p40492	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
AZOLI_p40493	COG1028	Short-chain dehydrogenase reductase Sdr
AZOLI_p40494	COG1917	Cupin 2, conserved barrel domain protein
AZOLI_p40496	COG0625	glutathione transferase activity
AZOLI_p40498	COG1942	4-Oxalocrotonate Tautomerase
AZOLI_p40499	COG1802	Transcriptional regulator
AZOLI_p40500	COG1904	glucuronate isomerase
AZOLI_p40501	COG2721	sulfolactate sulfo-lyase activity
AZOLI_p40503	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AZOLI_p40505	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AZOLI_p40506	COG0493	'glutamate synthase
AZOLI_p40506	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AZOLI_p40509	COG1309	transcriptional regulator
AZOLI_p40512	COG2198	Histidine kinase
AZOLI_p40512	COG0643	Histidine kinase
AZOLI_p40513	COG3706	GGDEF domain
AZOLI_p40513	COG0745	RESPONSE REGULATOR receiver
AZOLI_p40514	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AZOLI_p40516	COG2201	protein-glutamate methylesterase activity
AZOLI_p40517	COG0835	chemotaxis
AZOLI_p40518	COG0840	transmembrane signaling receptor activity
AZOLI_p40519	COG1776	CheC inhibitor of MCP methylation
AZOLI_p40519	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AZOLI_p40520	COG2201	protein-glutamate methylesterase activity
AZOLI_p40521	COG0457	Tetratricopeptide repeat
AZOLI_p40521	COG0859	PFAM glycosyl transferase family 9
AZOLI_p40522	COG1464	Belongs to the NlpA lipoprotein family
AZOLI_p40523	COG2011	ABC-type metal ion transport system permease component
AZOLI_p40524	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AZOLI_p40530	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AZOLI_p40532	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AZOLI_p40540	COG1530	ribonuclease E activity
AZOLI_p40547	COG3335	DDE superfamily endonuclease
AZOLI_p40554	COG0457	Tetratricopeptide repeat
AZOLI_p40554	COG0515	serine threonine protein kinase
AZOLI_p40556	COG0515	serine threonine protein kinase
AZOLI_p40557	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AZOLI_p40558	COG0631	protein serine/threonine phosphatase activity
AZOLI_p40576	COG0375	protein maturation
AZOLI_p40577	COG0649	NAD binding
AZOLI_p40578	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AZOLI_p40580	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AZOLI_p40581	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AZOLI_p40582	COG0651	ATP synthesis coupled electron transport
AZOLI_p40585	COG2414	aldehyde ferredoxin oxidoreductase
AZOLI_p40590	COG1522	sequence-specific DNA binding
AZOLI_p40591	COG0251	oxidation-reduction process
AZOLI_p40592	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AZOLI_p40595	COG0559	Belongs to the binding-protein-dependent transport system permease family
AZOLI_p40597	COG0411	ABC transporter
AZOLI_p40598	COG0410	ABC transporter
AZOLI_p40607	COG1045	serine acetyltransferase
AZOLI_p40614	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AZOLI_p40620	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AZOLI_p40621	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AZOLI_p40622	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AZOLI_p40633	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AZOLI_p40634	COG0347	Belongs to the P(II) protein family
AZOLI_p40640	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AZOLI_p40641	COG1121	(ABC) transporter
AZOLI_p40643	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AZOLI_p40644	COG0784	Response regulator, receiver
AZOLI_p40644	COG3437	response regulator, receiver
AZOLI_p40645	COG1280	lysine exporter protein (LysE YggA)
AZOLI_p40648	COG1396	sequence-specific DNA binding
AZOLI_p40648	COG3800	Transcriptional regulator
AZOLI_p40649	COG2224	Isocitrate lyase
AZOLI_p40651	COG0693	protein deglycase activity
AZOLI_p40654	COG0287	Prephenate dehydrogenase
AZOLI_p40655	COG0583	DNA-binding transcription factor activity
AZOLI_p40656	COG0450	alkyl hydroperoxide reductase
AZOLI_p50008	COG1706	bacterial-type flagellum-dependent cell motility
AZOLI_p50011	COG1749	Flagellar hook protein flgE
AZOLI_p50012	COG1360	Flagellar Motor Protein
AZOLI_p50013	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AZOLI_p50015	COG4786	Flagellar basal body rod
AZOLI_p50016	COG4786	Flagellar basal body rod
AZOLI_p50017	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
AZOLI_p50018	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AZOLI_p50020	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AZOLI_p50026	COG1766	The M ring may be actively involved in energy transduction
AZOLI_p50028	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AZOLI_p50029	COG1338	Plays a role in the flagellum-specific transport system
AZOLI_p50031	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AZOLI_p50035	COG0745	RESPONSE REGULATOR receiver
AZOLI_p50038	COG5443	negative regulation of bacterial-type flagellum assembly
AZOLI_p50044	COG1157	protein secretion by the type III secretion system
AZOLI_p50046	COG1558	bacterial-type flagellum-dependent cell motility
AZOLI_p50047	COG1677	Flagellar hook-basal body complex protein FliE
AZOLI_p50055	COG3293	Transposase
AZOLI_p50057	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AZOLI_p50059	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AZOLI_p50060	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AZOLI_p50061	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AZOLI_p50062	COG0351	phosphomethylpyrimidine kinase
AZOLI_p50063	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZOLI_p50076	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AZOLI_p50077	COG0569	domain protein
AZOLI_p50078	COG0625	glutathione transferase activity
AZOLI_p50080	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AZOLI_p50081	COG0573	inorganic phosphate transmembrane transporter activity
AZOLI_p50083	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AZOLI_p50090	COG1032	radical SAM domain protein
AZOLI_p50093	COG3920	Histidine kinase
AZOLI_p50097	COG0784	Response regulator, receiver
AZOLI_p50097	COG5002	protein histidine kinase activity
AZOLI_p50097	COG2205	protein histidine kinase activity
AZOLI_p50101	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AZOLI_p50103	COG1802	Transcriptional regulator
AZOLI_p50104	COG0246	Mannitol dehydrogenase
AZOLI_p50105	COG1063	alcohol dehydrogenase
AZOLI_p50106	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AZOLI_p50108	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AZOLI_p50110	COG3829	transcription factor binding
AZOLI_p50110	COG3290	protein histidine kinase activity
AZOLI_p50111	COG5002	protein histidine kinase activity
AZOLI_p50112	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AZOLI_p50113	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AZOLI_p50113	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AZOLI_p50115	COG3293	Transposase
AZOLI_p50132	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AZOLI_p50133	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AZOLI_p50136	COG4774	siderophore transport
AZOLI_p50138	COG1309	transcriptional regulator
AZOLI_p50147	COG3604	Transcriptional regulator
AZOLI_p50152	COG0179	Fumarylacetoacetate (FAA) hydrolase
AZOLI_p50153	COG1737	Transcriptional regulator
AZOLI_p50155	COG1538	Outer membrane efflux protein
AZOLI_p50158	COG2885	chlorophyll binding
AZOLI_p50158	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AZOLI_p50165	COG0411	ABC transporter
AZOLI_p50169	COG1940	carbohydrate kinase activity
AZOLI_p50173	COG0463	Glycosyl transferase, family 2
AZOLI_p50176	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZOLI_p50176	COG4191	Histidine kinase
AZOLI_p50177	COG1238	metal cluster binding
AZOLI_p50182	COG1858	cytochrome C peroxidase
AZOLI_p50186	COG0840	transmembrane signaling receptor activity
AZOLI_p50187	COG0789	Transcriptional regulator
AZOLI_p50190	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AZOLI_p50195	COG3842	ATPase activity
AZOLI_p50196	COG3842	ATPase activity
AZOLI_p50200	COG1349	DNA-binding transcription factor activity
AZOLI_p50201	COG0516	GMP reductase activity
AZOLI_p50203	COG0840	transmembrane signaling receptor activity
AZOLI_p50211	COG0697	spore germination
AZOLI_p50213	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZOLI_p50221	COG2814	Major facilitator Superfamily
AZOLI_p50224	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AZOLI_p50228	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZOLI_p50230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZOLI_p50232	COG2205	protein histidine kinase activity
AZOLI_p50232	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZOLI_p50235	COG0372	Belongs to the citrate synthase family
AZOLI_p50238	COG2204	response regulator
AZOLI_p50239	COG2186	Transcriptional regulator
AZOLI_p50241	COG0247	lactate metabolic process
AZOLI_p50242	COG1139	Iron-sulfur cluster binding protein
AZOLI_p50244	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZOLI_p50245	COG3283	Transcriptional regulator of aromatic amino acids metabolism
AZOLI_p50248	COG1573	uracil-dna glycosylase
AZOLI_p50249	COG0741	lytic transglycosylase activity
AZOLI_p50250	COG0521	Mo-molybdopterin cofactor biosynthetic process
AZOLI_p50253	COG2703	oxygen carrier activity
AZOLI_p50256	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AZOLI_p50258	COG2205	protein histidine kinase activity
AZOLI_p50258	COG2202	Pas domain
AZOLI_p50262	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AZOLI_p50262	COG3218	ABC-type transport auxiliary lipoprotein component
AZOLI_p50263	COG1127	ABC transporter
AZOLI_p50264	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AZOLI_p50265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AZOLI_p50269	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AZOLI_p50274	COG0840	transmembrane signaling receptor activity
AZOLI_p50283	COG0305	Participates in initiation and elongation during chromosome replication
AZOLI_p50284	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AZOLI_p50285	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AZOLI_p50286	COG1127	ABC transporter
AZOLI_p50295	COG2723	6-phospho-beta-galactosidase activity
AZOLI_p50299	COG2086	electron transfer activity
AZOLI_p50301	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZOLI_p50302	COG4993	Dehydrogenase
AZOLI_p50307	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AZOLI_p50311	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AZOLI_p50313	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AZOLI_p50314	COG0840	transmembrane signaling receptor activity
AZOLI_p50316	COG4178	(ABC) transporter
AZOLI_p50323	COG1988	membrane-bound metal-dependent
AZOLI_p50335	COG0477	Major facilitator Superfamily
AZOLI_p50336	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AZOLI_p50337	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AZOLI_p50338	COG1845	cytochrome c oxidase, subunit III
AZOLI_p50339	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AZOLI_p50342	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AZOLI_p50347	COG1032	radical SAM domain protein
AZOLI_p50348	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AZOLI_p50351	COG0406	alpha-ribazole phosphatase activity
AZOLI_p50354	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AZOLI_p50357	COG1648	precorrin-2 dehydrogenase activity
AZOLI_p50357	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AZOLI_p50358	COG0243	molybdopterin cofactor binding
AZOLI_p50360	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AZOLI_p50362	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZOLI_p50364	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZOLI_p50365	COG1116	anion transmembrane transporter activity
AZOLI_p50366	COG0656	L-ascorbic acid biosynthetic process
AZOLI_p50367	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AZOLI_p50369	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AZOLI_p50370	COG2017	converts alpha-aldose to the beta-anomer
AZOLI_p50371	COG1172	Belongs to the binding-protein-dependent transport system permease family
AZOLI_p50372	COG1172	Belongs to the binding-protein-dependent transport system permease family
AZOLI_p50373	COG1129	ABC transporter
AZOLI_p50374	COG1879	ABC-type sugar transport system periplasmic component
AZOLI_p50381	COG1129	ABC transporter
AZOLI_p50382	COG4214	carbohydrate transport
AZOLI_p50384	COG0129	dihydroxy-acid dehydratase activity
AZOLI_p50392	COG3706	GGDEF domain
AZOLI_p50393	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AZOLI_p50394	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZOLI_p50398	COG2814	Major facilitator Superfamily
AZOLI_p50400	COG0765	amino acid transport
AZOLI_p50401	COG0765	amino acid transport
AZOLI_p50402	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZOLI_p50403	COG1126	abc transporter atp-binding protein
AZOLI_p50404	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AZOLI_p50405	COG1609	Transcriptional regulator
AZOLI_p50407	COG0789	Transcriptional regulator
AZOLI_p50414	COG1192	Involved in chromosome partitioning
AZOLI_p50415	COG1475	DNA binding
AZOLI_p50416	COG0644	oxidoreductase
AZOLI_p50419	COG0318	PFAM AMP-dependent synthetase and ligase
AZOLI_p50421	COG3275	phosphorelay sensor kinase activity
AZOLI_p50422	COG3279	Response regulator of the LytR AlgR family
AZOLI_p50424	COG1309	transcriptional regulator
AZOLI_p50426	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZOLI_p50427	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AZOLI_p50430	COG1295	ribonuclease BN
AZOLI_p50432	COG1966	Carbon starvation protein
AZOLI_p50433	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AZOLI_p50438	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZOLI_p60002	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AZOLI_p60005	COG0438	transferase activity, transferring glycosyl groups
AZOLI_p60007	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AZOLI_p60014	COG0494	nUDIX hydrolase
AZOLI_p60016	COG1032	radical SAM domain protein
AZOLI_p60017	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AZOLI_p60022	COG0529	Catalyzes the synthesis of activated sulfate
AZOLI_p60024	COG3848	Pyruvate phosphate dikinase
AZOLI_p60024	COG0574	Belongs to the PEP-utilizing enzyme family
AZOLI_p60025	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AZOLI_p60036	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AZOLI_p60039	COG0022	dehydrogenase e1 component
AZOLI_p60040	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AZOLI_p60043	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AZOLI_p60061	COG2337	Toxic component of a toxin-antitoxin (TA) module
AZOLI_p60076	COG1083	cytidylyl-transferase
AZOLI_p60081	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AZOLI_p60088	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AZOLI_p60092	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AZOLI_p60097	COG2089	acid synthase
AZOLI_p60101	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AZOLI_p60108	COG1487	ribonuclease activity
AZOLI_p60109	COG4638	Rieske (2fe-2S)
AZOLI_p60120	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AZOLI_p60131	COG3293	Transposase
AZOLI_p60132	COG4372	Transposase
AZOLI_p60134	COG3436	PFAM IS66 Orf2 family protein
AZOLI_p60139	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AZOLI_p60140	COG1083	cytidylyl-transferase
AZOLI_p60142	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AZOLI_p60143	COG0107	imidazoleglycerol-phosphate synthase activity
AZOLI_p60158	COG0463	Glycosyl transferase, family 2
AZOLI_p60172	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AZOLI_p60173	COG1086	Polysaccharide biosynthesis protein
AZOLI_p60178	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AZOLI_p60182	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AZOLI_p60182	COG0662	Cupin 2, conserved barrel domain protein
AZOLI_p60186	COG2274	protein secretion by the type I secretion system
AZOLI_p60187	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZOLI_p60189	COG0463	Glycosyl transferase, family 2
AZOLI_p60192	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AZOLI_p60193	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AZOLI_p60196	COG1091	dTDP-4-dehydrorhamnose reductase activity
AZOLI_p60197	COG1088	dTDP-glucose 4,6-dehydratase activity
AZOLI_p60198	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AZOLI_p60199	COG1216	Glycosyl transferase, family 2
AZOLI_p60199	COG0438	transferase activity, transferring glycosyl groups
AZOLI_p60203	COG0175	sulfate reduction
AZOLI_p60207	COG0457	Tetratricopeptide repeat
AZOLI_p60207	COG0859	PFAM glycosyl transferase family 9
AZOLI_p60210	COG3416	Protein conserved in bacteria
AZOLI_p60216	COG3549	Plasmid maintenance system killer
AZOLI_p60218	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AZOLI_p60220	COG1686	Belongs to the peptidase S11 family
AZOLI_p60222	COG0789	Transcriptional regulator
AZOLI_p60223	COG2217	Heavy metal translocating P-type atpase
AZOLI_p60226	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AZOLI_p60227	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AZOLI_p60234	COG1192	Involved in chromosome partitioning
AZOLI_p60238	COG0438	transferase activity, transferring glycosyl groups
AZOLI_p60238	COG0297	glycogen (starch) synthase activity
AZOLI_p60239	COG2264	protein methyltransferase activity
AZOLI_p60240	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AZOLI_p60242	COG0463	Glycosyl transferase, family 2
AZOLI_p60245	COG3293	Transposase