locus-tag	class	description
HUE56_00010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUE56_00020	COG1091	dTDP-4-dehydrorhamnose reductase activity
HUE56_00025	COG1088	dTDP-glucose 4,6-dehydratase activity
HUE56_00030	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
HUE56_00035	COG0438	transferase activity, transferring glycosyl groups
HUE56_00035	COG1216	Glycosyl transferase, family 2
HUE56_00055	COG0175	sulfate reduction
HUE56_00065	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HUE56_00070	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HUE56_00085	COG0457	Tetratricopeptide repeat
HUE56_00085	COG0859	PFAM glycosyl transferase family 9
HUE56_00100	COG2321	neutral zinc metallopeptidase
HUE56_00110	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HUE56_00120	COG1686	Belongs to the peptidase S11 family
HUE56_00125	COG0784	Response regulator, receiver
HUE56_00125	COG4191	Histidine kinase
HUE56_00130	COG0789	Transcriptional regulator
HUE56_00140	COG2217	Heavy metal translocating P-type atpase
HUE56_00160	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HUE56_00175	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HUE56_00205	COG0784	Response regulator, receiver
HUE56_00205	COG4191	Histidine kinase
HUE56_00230	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HUE56_00265	COG1192	Involved in chromosome partitioning
HUE56_00285	COG0438	transferase activity, transferring glycosyl groups
HUE56_00290	COG2264	protein methyltransferase activity
HUE56_00295	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HUE56_00305	COG0463	Glycosyl transferase, family 2
HUE56_00325	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HUE56_00340	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUE56_00345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUE56_00365	COG1216	Glycosyl transferase, family 2
HUE56_00370	COG1216	Glycosyl transferase, family 2
HUE56_00370	COG0438	transferase activity, transferring glycosyl groups
HUE56_00400	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HUE56_00410	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HUE56_00415	COG2226	methyltransferase
HUE56_00435	COG0438	transferase activity, transferring glycosyl groups
HUE56_00465	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUE56_00485	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HUE56_00520	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HUE56_00535	COG1216	Glycosyl transferase, family 2
HUE56_00535	COG0438	transferase activity, transferring glycosyl groups
HUE56_00575	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HUE56_00640	COG0489	protein tyrosine kinase activity
HUE56_00640	COG3206	protein involved in exopolysaccharide biosynthesis
HUE56_00675	COG0438	transferase activity, transferring glycosyl groups
HUE56_00685	COG1132	(ABC) transporter
HUE56_00775	COG0438	transferase activity, transferring glycosyl groups
HUE56_00780	COG0438	transferase activity, transferring glycosyl groups
HUE56_00790	COG4520	surface antigen
HUE56_00795	COG0494	nUDIX hydrolase
HUE56_00820	COG0022	dehydrogenase e1 component
HUE56_00820	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUE56_00825	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HUE56_00830	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HUE56_00835	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HUE56_00840	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
HUE56_00840	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HUE56_00845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUE56_00860	COG2192	nodulation
HUE56_00900	COG1032	radical SAM domain protein
HUE56_00915	COG2192	nodulation
HUE56_00935	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUE56_00995	COG4638	Rieske (2fe-2S)
HUE56_01075	COG4106	trans-aconitate 2-methyltransferase activity
HUE56_01095	COG2818	Glycosylase
HUE56_01160	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HUE56_01165	COG1086	Polysaccharide biosynthesis protein
HUE56_01205	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
HUE56_01205	COG0662	Cupin 2, conserved barrel domain protein
HUE56_01215	COG2274	protein secretion by the type I secretion system
HUE56_01220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUE56_01235	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUE56_01235	COG1024	Enoyl-CoA hydratase
HUE56_01240	COG0183	Belongs to the thiolase family
HUE56_01275	COG2373	Large extracellular alpha-helical protein
HUE56_01315	COG0471	metal ion transport
HUE56_01315	COG3273	potassium ion transport
HUE56_01350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUE56_01360	COG1012	belongs to the aldehyde dehydrogenase family
HUE56_01365	COG1917	Cupin 2, conserved barrel domain protein
HUE56_01365	COG1396	sequence-specific DNA binding
HUE56_01375	COG1176	ABC-type spermidine putrescine transport system, permease component I
HUE56_01380	COG2182	Extracellular solute-binding protein
HUE56_01385	COG3842	ATPase activity
HUE56_01390	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
HUE56_01410	COG0583	DNA-binding transcription factor activity
HUE56_01430	COG0741	lytic transglycosylase activity
HUE56_01430	COG1196	nuclear chromosome segregation
HUE56_01430	COG0739	heme binding
HUE56_01450	COG2723	6-phospho-beta-galactosidase activity
HUE56_01460	COG2188	Transcriptional regulator
HUE56_01465	COG1228	amidohydrolase
HUE56_01470	COG0402	S-adenosylhomocysteine deaminase activity
HUE56_01475	COG2986	histidine ammonia-lyase
HUE56_01545	COG4336	lyase activity
HUE56_01555	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HUE56_01560	COG1984	allophanate hydrolase subunit 2
HUE56_01570	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
HUE56_01585	COG1104	cysteine desulfurase activity
HUE56_01600	COG0795	lipopolysaccharide-transporting ATPase activity
HUE56_01625	COG5002	protein histidine kinase activity
HUE56_01635	COG0745	RESPONSE REGULATOR receiver
HUE56_01665	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HUE56_01710	COG0697	spore germination
HUE56_01730	COG0542	response to heat
HUE56_01740	COG1028	Short-chain dehydrogenase reductase Sdr
HUE56_01775	COG1360	Flagellar Motor Protein
HUE56_01790	COG3501	Rhs element vgr protein
HUE56_01820	COG0583	DNA-binding transcription factor activity
HUE56_01825	COG0655	NAD(P)H dehydrogenase (quinone) activity
HUE56_01830	COG0435	Glutathione S-transferase
HUE56_01860	COG0408	coproporphyrinogen oxidase activity
HUE56_01865	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HUE56_01890	COG0643	Histidine kinase
HUE56_01890	COG2198	Histidine kinase
HUE56_01890	COG0784	Response regulator, receiver
HUE56_01895	COG3706	GGDEF domain
HUE56_01905	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUE56_01910	COG4770	biotin carboxylase activity
HUE56_01915	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUE56_01915	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUE56_01925	COG2095	MarC family integral membrane protein
HUE56_01945	COG1271	oxidase subunit
HUE56_01950	COG1294	oxidase, subunit
HUE56_01960	COG2080	2 iron, 2 sulfur cluster binding
HUE56_01975	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HUE56_01980	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HUE56_01985	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HUE56_01995	COG0356	it plays a direct role in the translocation of protons across the membrane
HUE56_02015	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HUE56_02025	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HUE56_02035	COG1012	belongs to the aldehyde dehydrogenase family
HUE56_02040	COG0028	Belongs to the TPP enzyme family
HUE56_02050	COG4178	(ABC) transporter
HUE56_02055	COG0154	amidase activity
HUE56_02085	COG5001	Diguanylate cyclase
HUE56_02085	COG5002	protein histidine kinase activity
HUE56_02105	COG0640	Transcriptional regulator
HUE56_02120	COG0123	including yeast histone deacetylase and acetoin utilization protein
HUE56_02135	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HUE56_02145	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
HUE56_02150	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
HUE56_02175	COG0583	DNA-binding transcription factor activity
HUE56_02180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUE56_02185	COG1522	sequence-specific DNA binding
HUE56_02190	COG4172	Belongs to the ABC transporter superfamily
HUE56_02195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUE56_02200	COG0601	transmembrane transport
HUE56_02205	COG0747	negative chemotaxis
HUE56_02220	COG0454	-acetyltransferase
HUE56_02230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUE56_02245	COG1012	belongs to the aldehyde dehydrogenase family
HUE56_02255	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HUE56_02275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUE56_02305	COG0659	secondary active sulfate transmembrane transporter activity
HUE56_02320	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
HUE56_02325	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HUE56_02335	COG5002	protein histidine kinase activity
HUE56_02335	COG0784	Response regulator, receiver
HUE56_02365	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HUE56_02380	COG0183	Belongs to the thiolase family
HUE56_02385	COG0318	PFAM AMP-dependent synthetase and ligase
HUE56_02390	COG1268	BioY protein
HUE56_02395	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HUE56_02400	COG1122	ATPase activity
HUE56_02405	COG2161	toxin-antitoxin pair type II binding
HUE56_02410	COG4115	mRNA cleavage
HUE56_02415	COG1126	abc transporter atp-binding protein
HUE56_02425	COG0765	amino acid transport
HUE56_02435	COG2188	Transcriptional regulator
HUE56_02440	COG2995	paraquat-inducible protein a
HUE56_02445	COG3008	intermembrane lipid transfer
HUE56_02460	COG0022	dehydrogenase e1 component
HUE56_02465	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HUE56_02470	COG1174	glycine betaine transport
HUE56_02475	COG1125	glycine betaine transport
HUE56_02480	COG1174	glycine betaine transport
HUE56_02485	COG1732	Glycine betaine
HUE56_02495	COG1335	isochorismatase
HUE56_02515	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
HUE56_02545	COG1737	Transcriptional regulator
HUE56_02555	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HUE56_02595	COG4566	intracellular signal transduction
HUE56_02615	COG0028	Belongs to the TPP enzyme family
HUE56_02620	COG0745	RESPONSE REGULATOR receiver
HUE56_02625	COG2205	protein histidine kinase activity
HUE56_02630	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HUE56_02640	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HUE56_02645	COG1028	Short-chain dehydrogenase reductase Sdr
HUE56_02650	COG1755	Isoprenylcysteine carboxyl methyltransferase
HUE56_02660	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HUE56_02675	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
HUE56_02685	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HUE56_02695	COG2204	response regulator
HUE56_02700	COG0375	protein maturation
HUE56_02765	COG1566	PFAM secretion protein HlyD family protein
HUE56_02775	COG3956	TIGRFAM MazG family protein
HUE56_02795	COG1233	COG1233 Phytoene dehydrogenase and related
HUE56_02805	COG1012	belongs to the aldehyde dehydrogenase family
HUE56_02815	COG1960	acyl-CoA dehydrogenase activity
HUE56_02820	COG0318	PFAM AMP-dependent synthetase and ligase
HUE56_02835	COG3180	Ammonia monooxygenase
HUE56_02850	COG2132	Multicopper oxidase
HUE56_02870	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
HUE56_02875	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
HUE56_02880	COG0583	DNA-binding transcription factor activity
HUE56_02915	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUE56_02915	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUE56_02920	COG1105	Belongs to the carbohydrate kinase PfkB family
HUE56_02925	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUE56_02925	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUE56_02930	COG1609	Transcriptional regulator
HUE56_02950	COG0489	protein tyrosine kinase activity
HUE56_02950	COG3206	protein involved in exopolysaccharide biosynthesis
HUE56_02970	COG0438	transferase activity, transferring glycosyl groups
HUE56_02985	COG0438	transferase activity, transferring glycosyl groups
HUE56_03005	COG2116	formate transmembrane transporter activity
HUE56_03010	COG2815	serine threonine protein kinase
HUE56_03010	COG0515	serine threonine protein kinase
HUE56_03020	COG1131	(ABC) transporter
HUE56_03040	COG0366	Alpha amylase catalytic
HUE56_03050	COG0066	3-isopropylmalate dehydratase activity
HUE56_03055	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HUE56_03060	COG3976	FMN-binding domain protein
HUE56_03060	COG1053	succinate dehydrogenase
HUE56_03065	COG1335	isochorismatase
HUE56_03110	COG2188	Transcriptional regulator
HUE56_03125	COG0459	protein refolding
HUE56_03150	COG3474	cytochrome
HUE56_03155	COG0346	lactoylglutathione lyase activity
HUE56_03175	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HUE56_03180	COG2084	Dehydrogenase
HUE56_03190	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HUE56_03195	COG3958	Transketolase
HUE56_03200	COG3959	Transketolase, thiamine diphosphate binding domain
HUE56_03205	COG1028	Short-chain dehydrogenase reductase Sdr
HUE56_03210	COG0583	DNA-binding transcription factor activity
HUE56_03220	COG0668	transmembrane transport
HUE56_03225	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
HUE56_03250	COG2207	Transcriptional regulator
HUE56_03265	COG1566	PFAM secretion protein HlyD family protein
HUE56_03270	COG0318	PFAM AMP-dependent synthetase and ligase
HUE56_03285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUE56_03290	COG1024	Enoyl-CoA hydratase
HUE56_03315	COG2814	Major facilitator Superfamily
HUE56_03320	COG2207	Transcriptional regulator
HUE56_03325	COG1522	sequence-specific DNA binding
HUE56_03330	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUE56_03330	COG2010	Cytochrome c
HUE56_03335	COG2080	2 iron, 2 sulfur cluster binding
HUE56_03340	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUE56_03340	COG2010	Cytochrome c
HUE56_03400	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
HUE56_03415	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HUE56_03420	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HUE56_03425	COG1028	Short-chain dehydrogenase reductase Sdr
HUE56_03430	COG1959	2 iron, 2 sulfur cluster binding
HUE56_03435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUE56_03440	COG1475	DNA binding
HUE56_03445	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HUE56_03480	COG1959	2 iron, 2 sulfur cluster binding
HUE56_03485	COG0719	Fe-S assembly protein
HUE56_03490	COG0396	ATPase activity
HUE56_03495	COG0719	Fe-S assembly protein
HUE56_03500	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HUE56_03505	COG0822	iron-sulfur transferase activity
HUE56_03510	COG2151	metal-sulfur cluster biosynthetic enzyme
HUE56_03515	COG0316	Belongs to the HesB IscA family
HUE56_03520	COG1741	Belongs to the pirin family
HUE56_03540	COG1414	Transcriptional regulator
HUE56_03545	COG3734	2-keto-3-deoxy-galactonokinase
HUE56_03550	COG0800	Aldolase
HUE56_03570	COG1028	Short-chain dehydrogenase reductase Sdr
HUE56_03575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUE56_03580	COG1942	4-Oxalocrotonate Tautomerase
HUE56_03585	COG0583	DNA-binding transcription factor activity
HUE56_03595	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HUE56_03605	COG0837	glucose binding
HUE56_03605	COG1737	Transcriptional regulator
HUE56_03610	COG1882	Formate acetyltransferase
HUE56_03615	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HUE56_03630	COG1609	Transcriptional regulator
HUE56_03640	COG0246	Mannitol dehydrogenase
HUE56_03645	COG1013	pyruvate-flavodoxin oxidoreductase activity
HUE56_03645	COG0674	pyruvate-flavodoxin oxidoreductase activity
HUE56_03645	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HUE56_03650	COG2271	Major facilitator Superfamily
HUE56_03660	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUE56_03680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUE56_03695	COG2197	response regulator
HUE56_03700	COG2205	protein histidine kinase activity
HUE56_03705	COG0243	molybdopterin cofactor binding
HUE56_03715	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HUE56_03715	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HUE56_03745	COG5002	protein histidine kinase activity
HUE56_03770	COG1177	transmembrane transport
HUE56_03775	COG1176	ABC-type spermidine putrescine transport system, permease component I
HUE56_03780	COG3842	ATPase activity
HUE56_03790	COG0535	radical SAM domain protein
HUE56_03810	COG2076	Multidrug Resistance protein
HUE56_03815	COG0546	phosphoglycolate phosphatase activity
HUE56_03815	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HUE56_03820	COG0174	glutamine synthetase
HUE56_03825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUE56_03835	COG0513	Belongs to the DEAD box helicase family
HUE56_03845	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUE56_03850	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HUE56_03850	COG1199	ATP-dependent helicase activity
HUE56_03855	COG0679	Auxin Efflux Carrier
HUE56_03865	COG2084	Dehydrogenase
HUE56_03875	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HUE56_03885	COG1196	nuclear chromosome segregation
HUE56_03890	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HUE56_03920	COG3047	cAMP biosynthetic process
HUE56_03930	COG2197	response regulator
HUE56_03935	COG1309	transcriptional regulator
HUE56_03940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUE56_03950	COG2721	sulfolactate sulfo-lyase activity
HUE56_03955	COG1904	glucuronate isomerase
HUE56_03960	COG1802	Transcriptional regulator
HUE56_03965	COG1917	Cupin 2, conserved barrel domain protein
HUE56_03970	COG1028	Short-chain dehydrogenase reductase Sdr
HUE56_03975	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HUE56_03980	COG1803	Methylglyoxal synthase
HUE56_03985	COG1802	Transcriptional regulator
HUE56_03995	COG2274	protein secretion by the type I secretion system
HUE56_04000	COG2274	protein secretion by the type I secretion system
HUE56_04015	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUE56_04020	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUE56_04040	COG0183	Belongs to the thiolase family
HUE56_04045	COG2050	protein possibly involved in aromatic compounds catabolism
HUE56_04050	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUE56_04055	COG1024	Enoyl-CoA hydratase
HUE56_04065	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUE56_04070	COG2151	metal-sulfur cluster biosynthetic enzyme
HUE56_04075	COG3396	Phenylacetate-CoA oxygenase
HUE56_04080	COG3460	Phenylacetate-CoA oxygenase
HUE56_04085	COG3396	Phenylacetate-CoA oxygenase
HUE56_04095	COG0693	protein deglycase activity
HUE56_04100	COG2224	Isocitrate lyase
HUE56_04105	COG1396	sequence-specific DNA binding
HUE56_04105	COG3800	Transcriptional regulator
HUE56_04120	COG1280	lysine exporter protein (LysE YggA)
HUE56_04125	COG3437	response regulator, receiver
HUE56_04125	COG0784	Response regulator, receiver
HUE56_04130	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HUE56_04140	COG1121	(ABC) transporter
HUE56_04145	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HUE56_04155	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HUE56_04165	COG0347	Belongs to the P(II) protein family
HUE56_04170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUE56_04220	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUE56_04230	COG2205	protein histidine kinase activity
HUE56_04230	COG2198	Histidine kinase
HUE56_04230	COG0784	Response regulator, receiver
HUE56_04240	COG1764	response to oxidative stress
HUE56_04245	COG0019	diaminopimelate decarboxylase activity
HUE56_04260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUE56_04265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUE56_04265	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUE56_04275	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HUE56_04285	COG1131	(ABC) transporter
HUE56_04315	COG0489	protein tyrosine kinase activity
HUE56_04315	COG3206	protein involved in exopolysaccharide biosynthesis
HUE56_04325	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HUE56_04335	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUE56_04350	COG0438	transferase activity, transferring glycosyl groups
HUE56_04355	COG1522	sequence-specific DNA binding
HUE56_04385	COG3093	addiction module antidote protein HigA
HUE56_04445	COG3436	PFAM IS66 Orf2 family protein
HUE56_04450	COG4372	Transposase
HUE56_04470	COG3436	PFAM IS66 Orf2 family protein
HUE56_04645	COG2189	Belongs to the N(4) N(6)-methyltransferase family
HUE56_04655	COG3012	SEC-C Motif Domain Protein
HUE56_04660	COG1278	Cold shock
HUE56_04705	COG0583	DNA-binding transcription factor activity
HUE56_04750	COG0559	Belongs to the binding-protein-dependent transport system permease family
HUE56_04810	COG2099	Precorrin-6x reductase
HUE56_04840	COG1797	cobyrinic acid a,c-diamide synthase activity
HUE56_04845	COG0778	Nitroreductase
HUE56_04855	COG2198	Histidine kinase
HUE56_04855	COG0643	Histidine kinase
HUE56_04865	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HUE56_04875	COG2201	protein-glutamate methylesterase activity
HUE56_04880	COG0835	chemotaxis
HUE56_04885	COG0840	transmembrane signaling receptor activity
HUE56_04890	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HUE56_04890	COG1776	CheC inhibitor of MCP methylation
HUE56_04895	COG2201	protein-glutamate methylesterase activity
HUE56_04900	COG0859	PFAM glycosyl transferase family 9
HUE56_04900	COG0457	Tetratricopeptide repeat
HUE56_04905	COG1464	Belongs to the NlpA lipoprotein family
HUE56_04910	COG2011	ABC-type metal ion transport system permease component
HUE56_04915	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HUE56_04935	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HUE56_04945	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUE56_04975	COG1530	ribonuclease E activity
HUE56_04980	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
HUE56_04995	COG1045	serine acetyltransferase
HUE56_05010	COG0287	Prephenate dehydrogenase
HUE56_05015	COG0583	DNA-binding transcription factor activity
HUE56_05030	COG1971	Probably functions as a manganese efflux pump
HUE56_05035	COG0402	S-adenosylhomocysteine deaminase activity
HUE56_05045	COG1309	transcriptional regulator
HUE56_05050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUE56_05055	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUE56_05080	COG0784	Response regulator, receiver
HUE56_05090	COG3214	Protein conserved in bacteria
HUE56_05095	COG1522	sequence-specific DNA binding
HUE56_05100	COG0586	Pfam SNARE associated Golgi protein
HUE56_05115	COG0427	acetyl-CoA hydrolase
HUE56_05130	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HUE56_05135	COG2202	Pas domain
HUE56_05135	COG2205	protein histidine kinase activity
HUE56_05150	COG1012	belongs to the aldehyde dehydrogenase family
HUE56_05155	COG2864	formate dehydrogenase
HUE56_05160	COG0437	4 iron, 4 sulfur cluster binding
HUE56_05165	COG3383	formate dehydrogenase (NAD+) activity
HUE56_05165	COG0243	molybdopterin cofactor binding
HUE56_05190	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HUE56_05210	COG4948	Mandelate Racemase Muconate Lactonizing
HUE56_05215	COG0583	DNA-binding transcription factor activity
HUE56_05245	COG0745	RESPONSE REGULATOR receiver
HUE56_05250	COG1278	Cold shock
HUE56_05275	COG0784	Response regulator, receiver
HUE56_05275	COG2198	Histidine kinase
HUE56_05275	COG0643	Histidine kinase
HUE56_05280	COG0835	chemotaxis
HUE56_05285	COG0643	Histidine kinase
HUE56_05285	COG2198	Histidine kinase
HUE56_05285	COG0784	Response regulator, receiver
HUE56_05305	COG2205	protein histidine kinase activity
HUE56_05320	COG3920	Histidine kinase
HUE56_05330	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HUE56_05345	COG0531	amino acid
HUE56_05355	COG4303	Ethanolamine ammonia lyase large subunit
HUE56_05375	COG1280	lysine exporter protein (LysE YggA)
HUE56_05395	COG2233	PERMEase
HUE56_05405	COG2723	6-phospho-beta-galactosidase activity
HUE56_05435	COG1295	ribonuclease BN
HUE56_05445	COG0861	Integral membrane protein TerC family
HUE56_05480	COG0793	Belongs to the peptidase S41A family
HUE56_05490	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HUE56_05495	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HUE56_05500	COG0671	phosphoesterase, PA-phosphatase related
HUE56_05515	COG0848	biopolymer transport protein
HUE56_05530	COG4221	oxidoreductase activity
HUE56_05545	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUE56_05555	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
HUE56_05560	COG1595	DNA-templated transcription, initiation
HUE56_05565	COG3806	Anti-sigma factor
HUE56_05580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUE56_05585	COG4597	amino acid ABC transporter
HUE56_05590	COG0765	amino acid transport
HUE56_05595	COG1126	abc transporter atp-binding protein
HUE56_05610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUE56_05635	COG0683	leucine binding
HUE56_05640	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HUE56_05645	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HUE56_05650	COG0183	Belongs to the thiolase family
HUE56_05655	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HUE56_05660	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUE56_05670	COG3485	protocatechuate 3,4-dioxygenase
HUE56_05675	COG3485	protocatechuate 3,4-dioxygenase
HUE56_05680	COG0840	transmembrane signaling receptor activity
HUE56_05685	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HUE56_05690	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HUE56_05700	COG3265	gluconokinase activity
HUE56_05705	COG1609	Transcriptional regulator
HUE56_05710	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
HUE56_05715	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HUE56_05725	COG0842	Transport permease protein
HUE56_05725	COG1129	ABC transporter
HUE56_05730	COG0842	Transport permease protein
HUE56_05740	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HUE56_05750	COG0564	pseudouridine synthase activity
HUE56_05805	COG1566	PFAM secretion protein HlyD family protein
HUE56_05815	COG0129	dihydroxy-acid dehydratase activity
HUE56_05820	COG1672	PFAM Archaeal ATPase
HUE56_05820	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
HUE56_05855	COG1028	Short-chain dehydrogenase reductase Sdr
HUE56_05860	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HUE56_05865	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HUE56_05870	COG2610	gluconate transmembrane transporter activity
HUE56_05875	COG2217	Heavy metal translocating P-type atpase
HUE56_05895	COG2884	Cell division ATP-binding protein ftsE
HUE56_05900	COG0318	PFAM AMP-dependent synthetase and ligase
HUE56_05900	COG0204	Acyl-transferase
HUE56_05960	COG2814	Major facilitator Superfamily
HUE56_05965	COG0667	Aldo Keto reductase
HUE56_06005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUE56_06010	COG0765	amino acid transport
HUE56_06030	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HUE56_06055	COG0588	phosphoglycerate mutase activity
HUE56_06060	COG0438	transferase activity, transferring glycosyl groups
HUE56_06075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUE56_06080	COG0601	transmembrane transport
HUE56_06105	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
HUE56_06140	COG1960	acyl-CoA dehydrogenase activity
HUE56_06150	COG1192	Involved in chromosome partitioning
HUE56_06155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUE56_06160	COG0667	Aldo Keto reductase
HUE56_06330	COG1396	sequence-specific DNA binding
HUE56_06355	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HUE56_06365	COG1522	sequence-specific DNA binding
HUE56_06395	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HUE56_06435	COG0583	DNA-binding transcription factor activity
HUE56_06440	COG0667	Aldo Keto reductase
HUE56_06450	COG0501	Belongs to the peptidase M48B family
HUE56_06455	COG0586	Pfam SNARE associated Golgi protein
HUE56_06460	COG0587	DNA-directed DNA polymerase activity
HUE56_06485	COG1028	Short-chain dehydrogenase reductase Sdr
HUE56_06490	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HUE56_06495	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HUE56_06545	COG1432	Conserved Protein
HUE56_06555	COG0675	Transposase, IS605 OrfB family
HUE56_06560	COG0675	Transposase, IS605 OrfB family
HUE56_06605	COG0564	pseudouridine synthase activity
HUE56_06650	COG1028	Short-chain dehydrogenase reductase Sdr
HUE56_06655	COG2972	Histidine kinase
HUE56_06655	COG0840	transmembrane signaling receptor activity
HUE56_06685	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUE56_06690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUE56_06695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUE56_06700	COG4774	siderophore transport
HUE56_06725	COG4585	Histidine kinase
HUE56_06760	COG0277	FAD linked oxidase domain protein
HUE56_06770	COG3842	ATPase activity
HUE56_06775	COG1176	ABC-type spermidine putrescine transport system, permease component I
HUE56_06780	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUE56_06800	COG1181	Belongs to the D-alanine--D-alanine ligase family
HUE56_06800	COG2918	glutathione biosynthetic process
HUE56_06820	COG0840	transmembrane signaling receptor activity
HUE56_06850	COG0686	Belongs to the AlaDH PNT family
HUE56_06855	COG1522	sequence-specific DNA binding
HUE56_06860	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HUE56_06870	COG1280	lysine exporter protein (LysE YggA)
HUE56_06880	COG2205	protein histidine kinase activity
HUE56_06880	COG0784	Response regulator, receiver
HUE56_06880	COG2198	Histidine kinase
HUE56_06910	COG0306	phosphate transporter
HUE56_06920	COG2202	Pas domain
HUE56_06920	COG2205	protein histidine kinase activity
HUE56_06940	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HUE56_06985	COG0405	Gamma-glutamyltransferase
HUE56_07005	COG2204	response regulator
HUE56_07030	COG2814	Major facilitator Superfamily
HUE56_07045	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
HUE56_07060	COG2084	Dehydrogenase
HUE56_07065	COG3622	Belongs to the hyi family
HUE56_07070	COG1902	pentaerythritol trinitrate reductase activity
HUE56_07070	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUE56_07075	COG1802	Transcriptional regulator
HUE56_07085	COG0861	Integral membrane protein TerC family
HUE56_07090	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HUE56_07100	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HUE56_07115	COG1309	transcriptional regulator
HUE56_07140	COG1028	Short-chain dehydrogenase reductase Sdr
HUE56_07160	COG4615	Cyclic peptide transporter
HUE56_07165	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUE56_07190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUE56_07250	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HUE56_07255	COG0583	DNA-binding transcription factor activity
HUE56_07275	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HUE56_07290	COG1028	Short-chain dehydrogenase reductase Sdr
HUE56_07295	COG1028	Short-chain dehydrogenase reductase Sdr
HUE56_07305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUE56_07330	COG0513	Belongs to the DEAD box helicase family
HUE56_07365	COG1475	DNA binding
HUE56_07370	COG1192	Involved in chromosome partitioning
HUE56_07380	COG4626	Terminase
HUE56_07380	COG1802	Transcriptional regulator
HUE56_07395	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUE56_07405	COG1028	Short-chain dehydrogenase reductase Sdr
HUE56_07410	COG0534	Mate efflux family protein
HUE56_07415	COG1309	transcriptional regulator
HUE56_07430	COG1850	ribulose-bisphosphate carboxylase activity
HUE56_07440	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HUE56_07460	COG1028	Short-chain dehydrogenase reductase Sdr
HUE56_07505	COG3842	ATPase activity
HUE56_07525	COG1475	DNA binding
HUE56_07530	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HUE56_07535	COG4221	oxidoreductase activity
HUE56_07545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUE56_07555	COG4521	taurine ABC transporter
HUE56_07560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUE56_07595	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HUE56_07615	COG0583	DNA-binding transcription factor activity
HUE56_07625	COG1028	Short-chain dehydrogenase reductase Sdr
HUE56_07630	COG4221	oxidoreductase activity
HUE56_07630	COG4221	oxidoreductase activity
HUE56_07640	COG2814	Major facilitator Superfamily
HUE56_07650	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HUE56_07660	COG0784	Response regulator, receiver
HUE56_07660	COG5002	protein histidine kinase activity
HUE56_07660	COG2198	Histidine kinase
HUE56_07700	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUE56_07705	COG1312	Catalyzes the dehydration of D-mannonate
HUE56_07710	COG0246	Mannitol dehydrogenase
HUE56_07720	COG0583	DNA-binding transcription factor activity
HUE56_07740	COG1012	belongs to the aldehyde dehydrogenase family
HUE56_07755	COG3976	FMN-binding domain protein
HUE56_07755	COG0431	NADPH-dependent FMN reductase
HUE56_07755	COG1053	succinate dehydrogenase
HUE56_07775	COG0559	Belongs to the binding-protein-dependent transport system permease family
HUE56_07790	COG2086	electron transfer activity
HUE56_07800	COG0183	Belongs to the thiolase family
HUE56_07810	COG0402	S-adenosylhomocysteine deaminase activity
HUE56_07835	COG0601	transmembrane transport
HUE56_07840	COG0747	negative chemotaxis
HUE56_07850	COG0583	DNA-binding transcription factor activity
HUE56_07870	COG0714	Associated with various cellular activities
HUE56_07890	COG4589	Belongs to the CDS family
HUE56_07900	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HUE56_07900	COG1213	nucleotidyl transferase
HUE56_07925	COG0754	glutathionylspermidine amidase activity
HUE56_07935	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HUE56_07945	COG1051	belongs to the nudix hydrolase family
HUE56_07945	COG1056	cytidyltransferase-related domain
HUE56_07950	COG1917	Cupin 2, conserved barrel domain protein
HUE56_07950	COG2207	Transcriptional regulator
HUE56_07975	COG1024	Enoyl-CoA hydratase
HUE56_08005	COG1309	transcriptional regulator
HUE56_08010	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HUE56_08015	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HUE56_08020	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HUE56_08025	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HUE56_08030	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HUE56_08045	COG3119	arylsulfatase activity
HUE56_08085	COG0747	negative chemotaxis
HUE56_08090	COG4172	Belongs to the ABC transporter superfamily
HUE56_08115	COG3712	iron ion homeostasis
HUE56_08130	COG1959	2 iron, 2 sulfur cluster binding
HUE56_08150	COG1959	2 iron, 2 sulfur cluster binding
HUE56_08155	COG0596	Alpha beta hydrolase
HUE56_08170	COG2205	protein histidine kinase activity
HUE56_08175	COG0745	RESPONSE REGULATOR receiver
HUE56_08185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUE56_08185	COG0785	Cytochrome C biogenesis protein
HUE56_08190	COG1846	Transcriptional regulator
HUE56_08215	COG2113	Glycine betaine
HUE56_08220	COG4176	ABC-type proline glycine betaine transport system permease component
HUE56_08240	COG0596	Alpha beta hydrolase
HUE56_08245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUE56_08250	COG1012	belongs to the aldehyde dehydrogenase family
HUE56_08270	COG0840	transmembrane signaling receptor activity
HUE56_08275	COG2271	Major facilitator Superfamily
HUE56_08280	COG1335	isochorismatase
HUE56_08285	COG3473	Maleate cis-trans isomerase
HUE56_08290	COG0596	Alpha beta hydrolase
HUE56_08295	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUE56_08300	COG2309	aminopeptidase activity
HUE56_08305	COG1846	Transcriptional regulator
HUE56_08310	COG2080	2 iron, 2 sulfur cluster binding
HUE56_08315	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUE56_08315	COG2010	Cytochrome c
HUE56_08325	COG1131	(ABC) transporter
HUE56_08330	COG0842	Transport permease protein
HUE56_08355	COG0183	Belongs to the thiolase family
HUE56_08360	COG2031	fatty acid transporter
HUE56_08365	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HUE56_08370	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HUE56_08375	COG2204	response regulator
HUE56_08380	COG3852	Histidine kinase
HUE56_08395	COG0784	Response regulator, receiver
HUE56_08400	COG2201	protein-glutamate methylesterase activity
HUE56_08420	COG1609	Transcriptional regulator
HUE56_08430	COG2271	Major facilitator Superfamily
HUE56_08465	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HUE56_08475	COG3239	Fatty acid desaturase
HUE56_08485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUE56_08490	COG0583	DNA-binding transcription factor activity
HUE56_08495	COG3608	succinylglutamate desuccinylase aspartoacylase
HUE56_08500	COG0747	negative chemotaxis
HUE56_08505	COG0601	transmembrane transport
HUE56_08515	COG0444	Belongs to the ABC transporter superfamily
HUE56_08520	COG4608	Belongs to the ABC transporter superfamily
HUE56_08525	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
HUE56_08535	COG2423	ornithine cyclodeaminase activity
HUE56_08540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUE56_08550	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
HUE56_08555	COG1177	transmembrane transport
HUE56_08560	COG1176	ABC-type spermidine putrescine transport system, permease component I
HUE56_08565	COG3842	ATPase activity
HUE56_08620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUE56_08630	COG0683	leucine binding
HUE56_08640	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUE56_08645	COG0411	ABC transporter
HUE56_08665	COG1116	anion transmembrane transporter activity
HUE56_08670	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUE56_08675	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUE56_08700	COG0649	NAD binding
HUE56_08705	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUE56_08715	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HUE56_08720	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUE56_08725	COG0651	ATP synthesis coupled electron transport
HUE56_08740	COG2414	aldehyde ferredoxin oxidoreductase
HUE56_08775	COG1028	Short-chain dehydrogenase reductase Sdr
HUE56_08780	COG3246	L-lysine catabolic process to acetate
HUE56_08785	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUE56_08790	COG2204	response regulator
HUE56_08800	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUE56_08810	COG2223	nitrite transmembrane transporter activity
HUE56_08825	COG2113	Glycine betaine
HUE56_08845	COG1902	pentaerythritol trinitrate reductase activity
HUE56_08845	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUE56_08850	COG0247	lactate metabolic process
HUE56_08850	COG2181	nitrate reductase activity
HUE56_08865	COG4175	Glycine betaine
HUE56_08870	COG4176	ABC-type proline glycine betaine transport system permease component
HUE56_08885	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HUE56_08900	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HUE56_08905	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
HUE56_08915	COG0189	ligase activity
HUE56_08920	COG3252	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT
HUE56_08930	COG0702	epimerase
HUE56_08945	COG1229	Formylmethanofuran dehydrogenase subunit A
HUE56_08950	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
HUE56_08990	COG1891	lyase activity
HUE56_09020	COG4974	Belongs to the 'phage' integrase family
HUE56_09030	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HUE56_09040	COG1187	pseudouridine synthase activity
HUE56_09045	COG1960	acyl-CoA dehydrogenase activity
HUE56_09060	COG0318	PFAM AMP-dependent synthetase and ligase
HUE56_09075	COG3162	membrane
HUE56_09090	COG2205	protein histidine kinase activity
HUE56_09090	COG2202	Pas domain
HUE56_09115	COG0584	glycerophosphoryl diester phosphodiesterase
HUE56_09120	COG1509	lysine 2,3-aminomutase activity
HUE56_09200	COG0745	RESPONSE REGULATOR receiver
HUE56_09220	COG0406	alpha-ribazole phosphatase activity
HUE56_09315	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HUE56_09340	COG2264	protein methyltransferase activity
HUE56_09360	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HUE56_09365	COG2205	protein histidine kinase activity
HUE56_09370	COG0745	RESPONSE REGULATOR receiver
HUE56_09385	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HUE56_09395	COG3842	ATPase activity
HUE56_09400	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HUE56_09405	COG3706	GGDEF domain
HUE56_09410	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HUE56_09415	COG0268	Binds directly to 16S ribosomal RNA
HUE56_09420	COG1024	Enoyl-CoA hydratase
HUE56_09430	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HUE56_09465	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
HUE56_09475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUE56_09485	COG0747	negative chemotaxis
HUE56_09490	COG4166	transmembrane transport
HUE56_09495	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HUE56_09510	COG0039	L-malate dehydrogenase activity
HUE56_09525	COG0598	Magnesium transport protein CorA
HUE56_09530	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HUE56_09535	COG1872	DUF167
HUE56_09555	COG0285	dihydrofolate synthase activity
HUE56_09560	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HUE56_09570	COG0133	tryptophan synthase activity
HUE56_09575	COG2205	protein histidine kinase activity
HUE56_09575	COG0784	Response regulator, receiver
HUE56_09585	COG2204	response regulator
HUE56_09590	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HUE56_09605	COG2205	protein histidine kinase activity
HUE56_09620	COG0802	atpase or kinase
HUE56_09630	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HUE56_09635	COG2887	Belongs to the helicase family. UvrD subfamily
HUE56_09650	COG1074	ATP-dependent DNA helicase activity
HUE56_09655	COG3118	belongs to the thioredoxin family
HUE56_09685	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HUE56_09735	COG3258	Cytochrome c
HUE56_09775	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HUE56_09820	COG2070	2-Nitropropane dioxygenase
HUE56_09825	COG0527	aspartate kinase activity
HUE56_09830	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HUE56_09835	COG4636	protein conserved in cyanobacteria
HUE56_09840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUE56_09845	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HUE56_09850	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HUE56_09855	COG1137	ATPase activity
HUE56_09870	COG0517	IMP dehydrogenase activity
HUE56_09870	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HUE56_09895	COG2223	nitrite transmembrane transporter activity
HUE56_09925	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HUE56_09930	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HUE56_09935	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HUE56_09950	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUE56_09955	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUE56_09965	COG1573	uracil-dna glycosylase
HUE56_09975	COG2154	pterin-4-alpha-carbinolamine dehydratase
HUE56_09985	COG4974	Belongs to the 'phage' integrase family
HUE56_10005	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HUE56_10050	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
HUE56_10070	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUE56_10080	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUE56_10080	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUE56_10090	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HUE56_10100	COG0642	Histidine kinase
HUE56_10105	COG0745	RESPONSE REGULATOR receiver
HUE56_10120	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
HUE56_10190	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HUE56_10210	COG0443	Heat shock 70 kDa protein
HUE56_10215	COG0484	heat shock protein binding
HUE56_10225	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HUE56_10230	COG0667	Aldo Keto reductase
HUE56_10245	COG4181	ATPase activity
HUE56_10255	COG0670	Belongs to the BI1 family
HUE56_10265	COG0745	RESPONSE REGULATOR receiver
HUE56_10270	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HUE56_10280	COG0573	inorganic phosphate transmembrane transporter activity
HUE56_10285	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HUE56_10290	COG5002	protein histidine kinase activity
HUE56_10305	COG0280	phosphate acetyltransferase
HUE56_10305	COG0281	malic enzyme
HUE56_10310	COG2814	Major facilitator Superfamily
HUE56_10315	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HUE56_10320	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HUE56_10325	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HUE56_10330	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HUE56_10345	COG0357	Ribosomal RNA small subunit methyltransferase G
HUE56_10350	COG0445	tRNA wobble uridine modification
HUE56_10370	COG1331	Highly conserved protein containing a thioredoxin domain
HUE56_10385	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HUE56_10390	COG0237	dephospho-CoA kinase activity
HUE56_10425	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HUE56_10430	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
HUE56_10440	COG4395	Tim44
HUE56_10445	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HUE56_10450	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HUE56_10510	COG4235	cytochrome complex assembly
HUE56_10515	COG3088	subunit of a heme lyase
HUE56_10520	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUE56_10525	COG1138	Cytochrome C-type biogenesis protein
HUE56_10530	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
HUE56_10540	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HUE56_10560	COG1185	polyribonucleotide nucleotidyltransferase activity
HUE56_10565	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HUE56_10570	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HUE56_10595	COG0779	Required for maturation of 30S ribosomal subunits
HUE56_10600	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HUE56_10605	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HUE56_10610	COG1396	sequence-specific DNA binding
HUE56_10615	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HUE56_10620	COG1253	flavin adenine dinucleotide binding
HUE56_10630	COG1702	phosphate starvation-inducible protein PhoH
HUE56_10635	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HUE56_10650	COG0302	gtp cyclohydrolase
HUE56_10655	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HUE56_10665	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HUE56_10670	COG0668	transmembrane transport
HUE56_10690	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HUE56_10705	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUE56_10715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUE56_10730	COG0730	response to heat
HUE56_10745	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
HUE56_10755	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUE56_10760	COG0745	RESPONSE REGULATOR receiver
HUE56_10780	COG0606	chelatase, subunit chli
HUE56_10795	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HUE56_10800	COG0180	Tryptophanyl-tRNA synthetase
HUE56_10815	COG0792	nuclease activity
HUE56_10820	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HUE56_10850	COG0569	domain protein
HUE56_10850	COG2985	domain, Protein
HUE56_10860	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HUE56_10865	COG0386	Belongs to the glutathione peroxidase family
HUE56_10890	COG0739	heme binding
HUE56_10940	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HUE56_10945	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HUE56_10955	COG2852	Protein conserved in bacteria
HUE56_10960	COG2890	protein-(glutamine-N5) methyltransferase activity
HUE56_10980	COG0542	response to heat
HUE56_10985	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HUE56_10995	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HUE56_11020	COG3162	membrane
HUE56_11040	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HUE56_11060	COG4106	trans-aconitate 2-methyltransferase activity
HUE56_11080	COG5001	Diguanylate cyclase
HUE56_11090	COG1473	amidohydrolase
HUE56_11095	COG3813	Protein conserved in bacteria
HUE56_11110	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HUE56_11150	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HUE56_11245	COG2423	ornithine cyclodeaminase activity
HUE56_11255	COG0776	regulation of translation
HUE56_11270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUE56_11300	COG0783	Belongs to the Dps family
HUE56_11310	COG0840	transmembrane signaling receptor activity
HUE56_11315	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HUE56_11320	COG0137	argininosuccinate synthase activity
HUE56_11355	COG1272	protein, Hemolysin III
HUE56_11405	COG0583	DNA-binding transcription factor activity
HUE56_11410	COG0477	Major facilitator Superfamily
HUE56_11415	COG1024	Enoyl-CoA hydratase
HUE56_11425	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HUE56_11425	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HUE56_11435	COG0138	bifunctional purine biosynthesis protein purh
HUE56_11455	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HUE56_11460	COG0583	DNA-binding transcription factor activity
HUE56_11475	COG1253	flavin adenine dinucleotide binding
HUE56_11485	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HUE56_11495	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HUE56_11540	COG3660	Nucleoside-diphosphate-sugar epimerase
HUE56_11545	COG1522	sequence-specific DNA binding
HUE56_11560	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HUE56_11565	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HUE56_11580	COG3005	denitrification pathway
HUE56_11590	COG0243	molybdopterin cofactor binding
HUE56_11610	COG2205	protein histidine kinase activity
HUE56_11620	COG2318	DinB family
HUE56_11625	COG1674	ftsk spoiiie
HUE56_11635	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HUE56_11645	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUE56_11650	COG1238	metal cluster binding
HUE56_11705	COG0539	negative regulation of cytoplasmic translation
HUE56_11715	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HUE56_11725	COG0574	Belongs to the PEP-utilizing enzyme family
HUE56_11725	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUE56_11730	COG1396	sequence-specific DNA binding
HUE56_11735	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
HUE56_11745	COG3668	Plasmid stabilization system
HUE56_11750	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HUE56_11770	COG1643	Atp-dependent helicase
HUE56_11805	COG4191	Histidine kinase
HUE56_11820	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUE56_11835	COG0045	succinate-CoA ligase (ADP-forming) activity
HUE56_11840	COG0039	L-malate dehydrogenase activity
HUE56_11870	COG0640	Transcriptional regulator
HUE56_11885	COG1970	mechanosensitive ion channel activity
HUE56_11890	COG0653	protein targeting
HUE56_11895	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HUE56_11900	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HUE56_11905	COG0494	nUDIX hydrolase
HUE56_11910	COG0514	ATP-dependent DNA helicase (RecQ)
HUE56_11920	COG0024	Methionine aminopeptidase
HUE56_11925	COG1489	DNA binding
HUE56_11930	COG1546	Belongs to the CinA family
HUE56_11930	COG1058	Belongs to the CinA family
HUE56_11960	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HUE56_11975	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HUE56_11980	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
HUE56_11995	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HUE56_12005	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HUE56_12010	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HUE56_12030	COG0126	phosphoglycerate kinase activity
HUE56_12045	COG4106	trans-aconitate 2-methyltransferase activity
HUE56_12055	COG4191	Histidine kinase
HUE56_12065	COG1278	Cold shock
HUE56_12080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUE56_12095	COG0840	transmembrane signaling receptor activity
HUE56_12100	COG4974	Belongs to the 'phage' integrase family
HUE56_12110	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HUE56_12130	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HUE56_12140	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HUE56_12150	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HUE56_12160	COG0625	glutathione transferase activity
HUE56_12165	COG0513	Belongs to the DEAD box helicase family
HUE56_12170	COG2032	superoxide dismutase activity
HUE56_12235	COG0167	dihydroorotate dehydrogenase activity
HUE56_12255	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HUE56_12260	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HUE56_12275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUE56_12290	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
HUE56_12320	COG3327	negative regulation of DNA-templated transcription, initiation
HUE56_12350	COG0625	glutathione transferase activity
HUE56_12375	COG1278	Cold shock
HUE56_12395	COG0586	Pfam SNARE associated Golgi protein
HUE56_12420	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HUE56_12430	COG2205	protein histidine kinase activity
HUE56_12445	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HUE56_12450	COG0681	Belongs to the peptidase S26 family
HUE56_12470	COG2350	Protein conserved in bacteria
HUE56_12485	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUE56_12500	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HUE56_12525	COG3279	Response regulator of the LytR AlgR family
HUE56_12540	COG2205	protein histidine kinase activity
HUE56_12540	COG5002	protein histidine kinase activity
HUE56_12540	COG0784	Response regulator, receiver
HUE56_12560	COG1595	DNA-templated transcription, initiation
HUE56_12580	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HUE56_12585	COG0242	peptide deformylase activity
HUE56_12590	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HUE56_12595	COG0101	tRNA pseudouridine synthase activity
HUE56_12600	COG4191	Histidine kinase
HUE56_12615	COG0747	negative chemotaxis
HUE56_12620	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HUE56_12635	COG2193	ferroxidase activity
HUE56_12645	COG1192	Involved in chromosome partitioning
HUE56_12650	COG0009	L-threonylcarbamoyladenylate synthase
HUE56_12665	COG0277	FAD linked oxidase domain protein
HUE56_12680	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
HUE56_12685	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HUE56_12695	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HUE56_12710	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HUE56_12720	COG1902	pentaerythritol trinitrate reductase activity
HUE56_12725	COG1278	Cold shock
HUE56_12775	COG0436	Aminotransferase
HUE56_12780	COG1028	Short-chain dehydrogenase reductase Sdr
HUE56_12795	COG1322	Protein conserved in bacteria
HUE56_12825	COG0071	Belongs to the small heat shock protein (HSP20) family
HUE56_12830	COG0579	oxidoreductase
HUE56_12835	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HUE56_12855	COG1366	Belongs to the anti-sigma-factor antagonist family
HUE56_12865	COG2201	protein-glutamate methylesterase activity
HUE56_12870	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
HUE56_12880	COG0840	transmembrane signaling receptor activity
HUE56_12885	COG0835	chemotaxis
HUE56_12890	COG2198	Histidine kinase
HUE56_12890	COG0643	Histidine kinase
HUE56_12895	COG0745	RESPONSE REGULATOR receiver
HUE56_12905	COG1051	belongs to the nudix hydrolase family
HUE56_12920	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HUE56_12925	COG0799	negative regulation of ribosome biogenesis
HUE56_12930	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HUE56_12935	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HUE56_12940	COG4942	peptidase
HUE56_12945	COG0793	Belongs to the peptidase S41A family
HUE56_12960	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUE56_12970	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HUE56_12975	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HUE56_12980	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HUE56_13000	COG0071	Belongs to the small heat shock protein (HSP20) family
HUE56_13010	COG0254	rRNA binding
HUE56_13015	COG1132	(ABC) transporter
HUE56_13020	COG0842	Transport permease protein
HUE56_13030	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
HUE56_13065	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
HUE56_13070	COG3243	poly(R)-hydroxyalkanoic acid synthase
HUE56_13075	COG0183	Belongs to the thiolase family
HUE56_13080	COG1028	Short-chain dehydrogenase reductase Sdr
HUE56_13085	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HUE56_13095	COG2835	tetraacyldisaccharide 4'-kinase activity
HUE56_13105	COG3118	belongs to the thioredoxin family
HUE56_13110	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
HUE56_13130	COG0463	Glycosyl transferase, family 2
HUE56_13140	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HUE56_13170	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HUE56_13190	COG0312	modulator of DNA gyrase
HUE56_13195	COG0004	ammonium transporteR
HUE56_13200	COG0047	phosphoribosylformylglycinamidine synthase activity
HUE56_13205	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HUE56_13210	COG1234	tRNA 3'-trailer cleavage
HUE56_13215	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HUE56_13220	COG2770	Histidine kinase
HUE56_13220	COG3437	response regulator, receiver
HUE56_13240	COG2197	response regulator
HUE56_13250	COG0751	glycine-tRNA ligase activity
HUE56_13255	COG0752	glycyl-tRNA synthetase alpha subunit
HUE56_13270	COG0519	Catalyzes the synthesis of GMP from XMP
HUE56_13300	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HUE56_13310	COG3852	Histidine kinase
HUE56_13315	COG4191	Histidine kinase
HUE56_13320	COG5002	protein histidine kinase activity
HUE56_13330	COG5002	protein histidine kinase activity
HUE56_13330	COG2176	DNA-directed DNA polymerase activity
HUE56_13335	COG0745	RESPONSE REGULATOR receiver
HUE56_13345	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HUE56_13370	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HUE56_13385	COG1104	cysteine desulfurase activity
HUE56_13395	COG5554	nitrogen fixation
HUE56_13410	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HUE56_13430	COG1309	transcriptional regulator
HUE56_13440	COG1131	(ABC) transporter
HUE56_13460	COG4191	Histidine kinase
HUE56_13460	COG0784	Response regulator, receiver
HUE56_13490	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HUE56_13515	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HUE56_13520	COG1346	cytolysis
HUE56_13525	COG1380	Effector of murein hydrolase LrgA
HUE56_13545	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HUE56_13550	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HUE56_13555	COG0793	Belongs to the peptidase S41A family
HUE56_13560	COG0557	exoribonuclease II activity
HUE56_13570	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HUE56_13585	COG1086	Polysaccharide biosynthesis protein
HUE56_13605	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HUE56_13630	COG0717	Belongs to the dCTP deaminase family
HUE56_13635	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HUE56_13650	COG0693	protein deglycase activity
HUE56_13655	COG2197	response regulator
HUE56_13660	COG2197	response regulator
HUE56_13665	COG0829	nickel cation binding
HUE56_13670	COG0831	urea catabolic process
HUE56_13675	COG0832	Belongs to the urease beta subunit family
HUE56_13680	COG0804	urea catabolic process
HUE56_13685	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HUE56_13690	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
HUE56_13695	COG0830	nickel cation binding
HUE56_13700	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HUE56_13715	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HUE56_13730	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HUE56_13735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUE56_13740	COG0028	Belongs to the TPP enzyme family
HUE56_13760	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HUE56_13765	COG0640	Transcriptional regulator
HUE56_13775	COG0768	penicillin binding
HUE56_13795	COG2862	Uncharacterized protein family, UPF0114
HUE56_13805	COG0140	phosphoribosyl-ATP diphosphatase activity
HUE56_13810	COG0500	methyltransferase
HUE56_13835	COG0583	DNA-binding transcription factor activity
HUE56_13900	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUE56_13905	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUE56_13910	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUE56_13915	COG0649	NAD binding
HUE56_13920	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
HUE56_13925	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HUE56_13930	COG1034	ATP synthesis coupled electron transport
HUE56_13935	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HUE56_13950	COG0713	ATP synthesis coupled electron transport
HUE56_13965	COG1007	ATP synthesis coupled electron transport
HUE56_13985	COG0346	lactoylglutathione lyase activity
HUE56_13995	COG0519	Catalyzes the synthesis of GMP from XMP
HUE56_14010	COG0442	prolyl-tRNA aminoacylation
HUE56_14020	COG1136	(ABC) transporter
HUE56_14030	COG1335	isochorismatase
HUE56_14035	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HUE56_14040	COG0564	pseudouridine synthase activity
HUE56_14045	COG0546	phosphoglycolate phosphatase activity
HUE56_14060	COG0354	folic acid binding
HUE56_14140	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HUE56_14155	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HUE56_14160	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HUE56_14170	COG0248	Ppx GppA phosphatase
HUE56_14190	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HUE56_14205	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HUE56_14210	COG0849	cell division
HUE56_14215	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HUE56_14220	COG1181	Belongs to the D-alanine--D-alanine ligase family
HUE56_14225	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HUE56_14230	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HUE56_14240	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HUE56_14250	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HUE56_14255	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HUE56_14265	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HUE56_14285	COG2001	Belongs to the MraZ family
HUE56_14295	COG3023	N-Acetylmuramoyl-L-alanine amidase
HUE56_14330	COG3284	Transcriptional regulator
HUE56_14345	COG0482	sulfurtransferase activity
HUE56_14355	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HUE56_14370	COG1045	serine acetyltransferase
HUE56_14375	COG2945	thiolester hydrolase activity
HUE56_14400	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HUE56_14405	COG0193	aminoacyl-tRNA hydrolase activity
HUE56_14415	COG1283	sodium-dependent phosphate transmembrane transporter activity
HUE56_14420	COG5001	Diguanylate cyclase
HUE56_14420	COG3300	MHYT domain
HUE56_14460	COG0418	dihydroorotase activity
HUE56_14465	COG1570	exodeoxyribonuclease VII activity
HUE56_14485	COG0590	tRNA wobble adenosine to inosine editing
HUE56_14490	COG1187	pseudouridine synthase activity
HUE56_14495	COG0742	ribosomal rna small subunit methyltransferase
HUE56_14510	COG0366	Alpha amylase catalytic
HUE56_14520	COG2910	NAD(P)H-binding
HUE56_14525	COG2337	Toxic component of a toxin-antitoxin (TA) module
HUE56_14535	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HUE56_14570	COG2197	response regulator
HUE56_14575	COG2197	response regulator
HUE56_14580	COG0210	DNA helicase
HUE56_14590	COG2264	protein methyltransferase activity
HUE56_14600	COG0006	proline dipeptidase activity
HUE56_14620	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUE56_14625	COG0497	DNA recombination
HUE56_14630	COG0583	DNA-binding transcription factor activity
HUE56_14635	COG0494	nUDIX hydrolase
HUE56_14640	COG4251	negative regulation of phosphorylation
HUE56_14645	COG0357	Ribosomal RNA small subunit methyltransferase G
HUE56_14645	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUE56_14660	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HUE56_14660	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HUE56_14665	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HUE56_14675	COG2205	protein histidine kinase activity
HUE56_14690	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
HUE56_14705	COG0523	cobalamin synthesis protein
HUE56_14710	COG0735	belongs to the Fur family
HUE56_14715	COG0415	Belongs to the DNA photolyase family
HUE56_14730	COG1201	RNA secondary structure unwinding
HUE56_14740	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
HUE56_14745	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HUE56_14750	COG0242	peptide deformylase activity
HUE56_14775	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
HUE56_14785	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HUE56_14795	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HUE56_14800	COG0154	amidase activity
HUE56_14825	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HUE56_14830	COG1116	anion transmembrane transporter activity
HUE56_14870	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HUE56_14870	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HUE56_14925	COG0551	DNA topoisomerase type I activity
HUE56_14925	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HUE56_14935	COG0251	oxidation-reduction process
HUE56_14940	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HUE56_14955	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HUE56_14970	COG0203	ribosomal protein L17
HUE56_14975	COG1238	metal cluster binding
HUE56_14990	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HUE56_15010	COG5002	protein histidine kinase activity
HUE56_15010	COG5001	Diguanylate cyclase
HUE56_15010	COG3447	MASE1 domain protein
HUE56_15030	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HUE56_15070	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HUE56_15175	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HUE56_15180	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HUE56_15190	COG2873	o-acetylhomoserine
HUE56_15195	COG1832	CoA-binding protein
HUE56_15200	COG1024	Enoyl-CoA hydratase
HUE56_15205	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HUE56_15210	COG0758	DNA mediated transformation
HUE56_15220	COG1024	Enoyl-CoA hydratase
HUE56_15230	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
HUE56_15240	COG1309	transcriptional regulator
HUE56_15285	COG4651	solute:proton antiporter activity
HUE56_15285	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HUE56_15315	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
HUE56_15330	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
HUE56_15340	COG4786	Flagellar basal body rod
HUE56_15345	COG4786	Flagellar basal body rod
HUE56_15370	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HUE56_15375	COG1381	Involved in DNA repair and RecF pathway recombination
HUE56_15405	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
HUE56_15410	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HUE56_15410	COG0321	lipoyl(octanoyl) transferase activity
HUE56_15415	COG0084	hydrolase, TatD family'
HUE56_15425	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HUE56_15430	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HUE56_15435	COG1686	Belongs to the peptidase S11 family
HUE56_15460	COG0488	(ABC) transporter
HUE56_15465	COG1012	belongs to the aldehyde dehydrogenase family
HUE56_15470	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
HUE56_15480	COG0105	UTP biosynthetic process
HUE56_15500	COG0745	RESPONSE REGULATOR receiver
HUE56_15520	COG2815	serine threonine protein kinase
HUE56_15520	COG0515	serine threonine protein kinase
HUE56_15545	COG0500	methyltransferase
HUE56_15615	COG3501	Rhs element vgr protein
HUE56_15665	COG2208	phosphoserine phosphatase activity
HUE56_15665	COG2770	Histidine kinase
HUE56_15670	COG1366	Belongs to the anti-sigma-factor antagonist family
HUE56_15690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUE56_15695	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUE56_15705	COG4191	Histidine kinase
HUE56_15730	COG2951	lytic endotransglycosylase activity
HUE56_15755	COG0114	fumarate hydratase activity
HUE56_15775	COG5002	protein histidine kinase activity
HUE56_15775	COG5001	Diguanylate cyclase
HUE56_15790	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HUE56_15795	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HUE56_15810	COG0205	6-phosphofructokinase activity
HUE56_15835	COG0288	reversible hydration of carbon dioxide
HUE56_15840	COG0163	prenyltransferase activity
HUE56_15850	COG0604	alcohol dehydrogenase
HUE56_15850	COG3321	synthase
HUE56_15850	COG1028	Short-chain dehydrogenase reductase Sdr
HUE56_15905	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUE56_15910	COG0840	transmembrane signaling receptor activity
HUE56_15920	COG2197	response regulator
HUE56_15935	COG1160	GTP binding
HUE56_15940	COG2900	Belongs to the SlyX family
HUE56_15945	COG1914	H( )-stimulated, divalent metal cation uptake system
HUE56_15980	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HUE56_15980	COG0519	Catalyzes the synthesis of GMP from XMP
HUE56_15985	COG1247	-acetyltransferase
HUE56_15995	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HUE56_16010	COG1758	RNA polymerase activity
HUE56_16020	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HUE56_16030	COG0681	Belongs to the peptidase S26 family
HUE56_16035	COG0571	ribonuclease III activity
HUE56_16040	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HUE56_16055	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
HUE56_16065	COG1752	Esterase of the alpha-beta hydrolase superfamily
HUE56_16090	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
HUE56_16100	COG1338	Plays a role in the flagellum-specific transport system
HUE56_16115	COG2257	FlhB HrpN YscU SpaS Family
HUE56_16120	COG1815	bacterial-type flagellum-dependent cell motility
HUE56_16125	COG1558	bacterial-type flagellum-dependent cell motility
HUE56_16130	COG1677	Flagellar hook-basal body complex protein FliE
HUE56_16135	COG1987	bacterial-type flagellum assembly
HUE56_16145	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HUE56_16185	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HUE56_16195	COG2076	Multidrug Resistance protein
HUE56_16215	COG0312	modulator of DNA gyrase
HUE56_16225	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HUE56_16230	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HUE56_16235	COG0109	protoheme IX farnesyltransferase activity
HUE56_16245	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
HUE56_16250	COG1845	cytochrome c oxidase, subunit III
HUE56_16260	COG3346	SURF1 family
HUE56_16270	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HUE56_16280	COG3237	CsbD-like
HUE56_16295	COG1742	UPF0060 membrane protein
HUE56_16305	COG5001	Diguanylate cyclase
HUE56_16310	COG1840	ABC-type Fe3 transport system, periplasmic component
HUE56_16315	COG3842	ATPase activity
HUE56_16320	COG1132	(ABC) transporter
HUE56_16325	COG1752	Esterase of the alpha-beta hydrolase superfamily
HUE56_16345	COG1178	ABC-type Fe3 transport system permease component
HUE56_16365	COG2226	methyltransferase
HUE56_16380	COG1196	nuclear chromosome segregation
HUE56_16380	COG0741	lytic transglycosylase activity
HUE56_16380	COG0739	heme binding
HUE56_16390	COG5487	UPF0391 membrane protein
HUE56_16400	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUE56_16405	COG1765	OsmC-like protein
HUE56_16425	COG0728	peptidoglycan biosynthetic process
HUE56_16430	COG2205	protein histidine kinase activity
HUE56_16445	COG2086	electron transfer activity
HUE56_16455	COG0789	Transcriptional regulator
HUE56_16460	COG0318	PFAM AMP-dependent synthetase and ligase
HUE56_16480	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HUE56_16485	COG1360	Flagellar Motor Protein
HUE56_16490	COG2308	Evidence 4 Homologs of previously reported genes of
HUE56_16535	COG0626	cystathionine gamma-synthase activity
HUE56_16540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUE56_16545	COG4597	amino acid ABC transporter
HUE56_16550	COG0765	amino acid transport
HUE56_16555	COG1126	abc transporter atp-binding protein
HUE56_16560	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HUE56_16570	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HUE56_16590	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HUE56_16595	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HUE56_16620	COG2199	diguanylate cyclase activity
HUE56_16620	COG2203	Gaf domain
HUE56_16630	COG0556	nucleotide-excision repair
HUE56_16635	COG0741	lytic transglycosylase activity
HUE56_16670	COG4957	zinc ion binding
HUE56_16675	COG0776	regulation of translation
HUE56_16690	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUE56_16700	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HUE56_16705	COG0540	Belongs to the ATCase OTCase family
HUE56_16710	COG0583	DNA-binding transcription factor activity
HUE56_16735	COG0672	)-iron permease
HUE56_16750	COG4120	Belongs to the binding-protein-dependent transport system permease family
HUE56_16780	COG1028	Short-chain dehydrogenase reductase Sdr
HUE56_16790	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HUE56_16795	COG1763	Mo-molybdopterin cofactor biosynthetic process
HUE56_16805	COG0546	phosphoglycolate phosphatase activity
HUE56_16815	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HUE56_16820	COG0314	molybdopterin synthase activity
HUE56_16825	COG1678	Uncharacterized ACR, COG1678
HUE56_16830	COG4232	protein-disulfide reductase activity
HUE56_16835	COG2824	Alkylphosphonate utilization operon protein PhnA
HUE56_16840	COG0678	peroxiredoxin activity
HUE56_16850	COG0328	RNA-DNA hybrid ribonuclease activity
HUE56_16855	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HUE56_16860	COG2833	Protein of unknown function (DUF455)
HUE56_16865	COG1218	3'(2'),5'-bisphosphate nucleotidase
HUE56_16885	COG3287	FIST C domain
HUE56_16885	COG2200	EAL domain
HUE56_16885	COG2199	diguanylate cyclase activity
HUE56_16895	COG2135	peptidase activity
HUE56_16910	COG2261	transglycosylase associated protein
HUE56_16920	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HUE56_16925	COG0725	ABC transporter, periplasmic molybdate-binding protein
HUE56_16930	COG4149	molybdate abc transporter
HUE56_16950	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HUE56_16955	COG0022	dehydrogenase e1 component
HUE56_16955	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUE56_16960	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUE56_16970	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUE56_16980	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HUE56_16985	COG2867	negative regulation of translational initiation
HUE56_16990	COG1942	4-Oxalocrotonate Tautomerase
HUE56_17030	COG2204	response regulator
HUE56_17040	COG1923	regulation of RNA biosynthetic process
HUE56_17045	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HUE56_17060	COG0483	inositol monophosphate 1-phosphatase activity
HUE56_17070	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HUE56_17075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUE56_17080	COG1116	anion transmembrane transporter activity
HUE56_17085	COG0123	including yeast histone deacetylase and acetoin utilization protein
HUE56_17115	COG0629	single-stranded DNA binding
HUE56_17120	COG0583	DNA-binding transcription factor activity
HUE56_17125	COG2814	Major facilitator Superfamily
HUE56_17130	COG2226	methyltransferase
HUE56_17160	COG0714	Associated with various cellular activities
HUE56_17175	COG0617	tRNA 3'-terminal CCA addition
HUE56_17190	COG0248	Ppx GppA phosphatase
HUE56_17195	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HUE56_17200	COG2062	phosphohistidine phosphatase, SixA
HUE56_17210	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HUE56_17240	COG1562	ergosterol biosynthetic process
HUE56_17245	COG1562	ergosterol biosynthetic process
HUE56_17250	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HUE56_17255	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HUE56_17270	COG3737	Protein of unknown function (DUF498/DUF598)
HUE56_17280	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUE56_17285	COG1862	Preprotein translocase
HUE56_17300	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HUE56_17310	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HUE56_17315	COG2814	Major facilitator Superfamily
HUE56_17320	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HUE56_17350	COG3784	Protein of unknown function (DUF1318)
HUE56_17380	COG0583	DNA-binding transcription factor activity
HUE56_17390	COG1028	Short-chain dehydrogenase reductase Sdr
HUE56_17410	COG2010	Cytochrome c
HUE56_17415	COG2308	Evidence 4 Homologs of previously reported genes of
HUE56_17415	COG2307	Protein conserved in bacteria
HUE56_17420	COG1305	Transglutaminase-like
HUE56_17425	COG0745	RESPONSE REGULATOR receiver
HUE56_17435	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HUE56_17440	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HUE56_17445	COG0058	SHG alpha-glucan phosphorylase activity
HUE56_17450	COG0456	acetyltransferase
HUE56_17460	COG1028	Short-chain dehydrogenase reductase Sdr
HUE56_17475	COG2264	protein methyltransferase activity
HUE56_17485	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HUE56_17500	COG0559	Belongs to the binding-protein-dependent transport system permease family
HUE56_17515	COG1846	Transcriptional regulator
HUE56_17520	COG1024	Enoyl-CoA hydratase
HUE56_17525	COG1597	lipid kinase activity
HUE56_17535	COG0113	porphobilinogen synthase activity
HUE56_17540	COG1881	PFAM PEBP family protein
HUE56_17555	COG0667	Aldo Keto reductase
HUE56_17560	COG2813	Specifically methylates the guanine in position
HUE56_17565	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HUE56_17570	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUE56_17575	COG0741	lytic transglycosylase activity
HUE56_17590	COG0534	Mate efflux family protein
HUE56_17595	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HUE56_17600	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HUE56_17635	COG0577	efflux transmembrane transporter activity
HUE56_17635	COG1136	(ABC) transporter
HUE56_17640	COG1136	(ABC) transporter
HUE56_17645	COG1566	PFAM secretion protein HlyD family protein
HUE56_17655	COG2877	3-deoxy-8-phosphooctulonate synthase activity
HUE56_17680	COG0149	triose-phosphate isomerase activity
HUE56_17690	COG1846	Transcriptional regulator
HUE56_17700	COG0745	RESPONSE REGULATOR receiver
HUE56_17710	COG2197	response regulator
HUE56_17720	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUE56_17725	COG0330	HflC and HflK could
HUE56_17730	COG0330	HflC and HflK could
HUE56_17735	COG0489	protein tyrosine kinase activity
HUE56_17740	COG0443	Heat shock 70 kDa protein
HUE56_17745	COG1028	Short-chain dehydrogenase reductase Sdr
HUE56_17770	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HUE56_17775	COG2205	protein histidine kinase activity
HUE56_17775	COG0784	Response regulator, receiver
HUE56_17775	COG5002	protein histidine kinase activity
HUE56_17785	COG2208	phosphoserine phosphatase activity
HUE56_17790	COG1366	Belongs to the anti-sigma-factor antagonist family
HUE56_17825	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HUE56_17830	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HUE56_17905	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HUE56_17915	COG1396	sequence-specific DNA binding
HUE56_17950	COG0124	histidyl-tRNA synthetase
HUE56_17955	COG1846	Transcriptional regulator
HUE56_17960	COG0300	oxidoreductase activity
HUE56_17970	COG0628	permease
HUE56_17975	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HUE56_17985	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HUE56_17990	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HUE56_18000	COG0525	valine-tRNA ligase activity
HUE56_18010	COG1538	Outer membrane efflux protein
HUE56_18020	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HUE56_18050	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUE56_18055	COG0494	nUDIX hydrolase
HUE56_18065	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HUE56_18070	COG2897	thiosulfate sulfurtransferase activity
HUE56_18075	COG0456	acetyltransferase
HUE56_18075	COG0454	-acetyltransferase
HUE56_18085	COG1492	cobalamin metabolic process
HUE56_18150	COG0315	cyclic pyranopterin monophosphate synthase activity
HUE56_18155	COG0303	'Molybdopterin
HUE56_18160	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HUE56_18165	COG0658	competence protein
HUE56_18165	COG2333	competence protein COMEC
HUE56_18170	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HUE56_18185	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
HUE56_18195	COG4977	sequence-specific DNA binding
HUE56_18205	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HUE56_18210	COG3494	Protein of unknown function (DUF1009)
HUE56_18235	COG0750	zinc metalloprotease
HUE56_18240	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HUE56_18250	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HUE56_18255	COG0233	cytoplasmic translational termination
HUE56_18260	COG0528	UMP kinase activity
HUE56_18265	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HUE56_18270	COG0052	Belongs to the universal ribosomal protein uS2 family
HUE56_18275	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HUE56_18280	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HUE56_18295	COG1561	YicC-like family, N-terminal region
HUE56_18330	COG0513	Belongs to the DEAD box helicase family
HUE56_18365	COG0187	DNA topoisomerase II activity
HUE56_18370	COG1607	acyl-coa hydrolase
HUE56_18380	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HUE56_18385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUE56_18415	COG4191	Histidine kinase
HUE56_18415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUE56_18430	COG0784	Response regulator, receiver
HUE56_18430	COG3437	response regulator, receiver
HUE56_18440	COG0140	phosphoribosyl-ATP diphosphatase activity
HUE56_18470	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HUE56_18485	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HUE56_18490	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUE56_18505	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HUE56_18515	COG0360	Binds together with S18 to 16S ribosomal RNA
HUE56_18520	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HUE56_18530	COG0359	binds to the 23S rRNA
HUE56_18535	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUE56_18540	COG0538	isocitrate dehydrogenase activity
HUE56_18550	COG0330	HflC and HflK could
HUE56_18575	COG0473	3-isopropylmalate dehydrogenase activity
HUE56_18615	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HUE56_18645	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HUE56_18650	COG4221	oxidoreductase activity
HUE56_18655	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HUE56_18670	COG0024	Methionine aminopeptidase
HUE56_18675	COG0494	nUDIX hydrolase
HUE56_18685	COG2132	Multicopper oxidase
HUE56_18700	COG4953	penicillin-binding protein 1C
HUE56_18705	COG2373	Large extracellular alpha-helical protein
HUE56_18720	COG0583	DNA-binding transcription factor activity
HUE56_18725	COG0303	'Molybdopterin
HUE56_18730	COG1324	tolerance protein
HUE56_18750	COG1494	fructose-1,6-bisphosphatase
HUE56_18760	COG0436	Aminotransferase
HUE56_18765	COG3290	protein histidine kinase activity
HUE56_18765	COG0840	transmembrane signaling receptor activity
HUE56_18770	COG0745	RESPONSE REGULATOR receiver
HUE56_18780	COG0616	signal peptide processing
HUE56_18790	COG0628	permease
HUE56_18795	COG2205	protein histidine kinase activity
HUE56_18805	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUE56_18810	COG0432	Pfam Uncharacterised protein family UPF0047
HUE56_18830	COG0745	RESPONSE REGULATOR receiver
HUE56_18835	COG3850	Histidine kinase
HUE56_18835	COG2205	protein histidine kinase activity
HUE56_18835	COG3437	response regulator, receiver
HUE56_18835	COG4999	Histidine kinase
HUE56_18845	COG0784	Response regulator, receiver
HUE56_18850	COG4251	negative regulation of phosphorylation
HUE56_18855	COG4251	negative regulation of phosphorylation
HUE56_18860	COG0840	transmembrane signaling receptor activity
HUE56_18865	COG0439	Biotin carboxylase
HUE56_18870	COG0511	ligase activity, forming carbon-carbon bonds
HUE56_18905	COG3108	Peptidase M15
HUE56_18910	COG3409	Peptidoglycan-binding domain 1 protein
HUE56_18910	COG0860	N-Acetylmuramoyl-L-alanine amidase
HUE56_18915	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HUE56_18940	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HUE56_18975	COG1136	(ABC) transporter
HUE56_18980	COG0577	efflux transmembrane transporter activity
HUE56_18980	COG1136	(ABC) transporter
HUE56_18995	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HUE56_19010	COG1610	YqeY-like protein
HUE56_19025	COG1403	HNH endonuclease
HUE56_19035	COG2890	protein-(glutamine-N5) methyltransferase activity
HUE56_19040	COG1393	Belongs to the ArsC family
HUE56_19045	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HUE56_19060	COG1846	Transcriptional regulator
HUE56_19065	COG1764	response to oxidative stress
HUE56_19090	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUE56_19095	COG0416	fatty acid biosynthetic process
HUE56_19100	COG0333	Belongs to the bacterial ribosomal protein bL32 family
HUE56_19120	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HUE56_19120	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HUE56_19130	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUE56_19130	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUE56_19140	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HUE56_19155	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
HUE56_19160	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HUE56_19165	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HUE56_19170	COG0698	ribose 5-phosphate isomerase
HUE56_19175	COG4957	zinc ion binding
HUE56_19190	COG3685	Protein conserved in bacteria
HUE56_19205	COG2153	protein acetylation
HUE56_19235	COG0259	pyridoxamine-phosphate oxidase activity
HUE56_19240	COG4520	surface antigen
HUE56_19250	COG1295	ribonuclease BN
HUE56_19255	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HUE56_19275	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HUE56_19280	COG0037	tRNA processing
HUE56_19290	COG2885	chlorophyll binding
HUE56_19305	COG0848	biopolymer transport protein
HUE56_19315	COG0824	Thioesterase
HUE56_19320	COG2255	four-way junction helicase activity
HUE56_19335	COG0217	transcriptional regulatory protein
HUE56_19345	COG1692	metallophosphoesterase
HUE56_19350	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HUE56_19400	COG1830	Aldolase
HUE56_19405	COG0352	thiamine-phosphate diphosphorylase activity
HUE56_19410	COG0730	response to heat
HUE56_19425	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HUE56_19430	COG0483	inositol monophosphate 1-phosphatase activity
HUE56_19450	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUE56_19455	COG0612	Peptidase, M16
HUE56_19465	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HUE56_19475	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HUE56_19475	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
HUE56_19480	COG0243	molybdopterin cofactor binding
HUE56_19505	COG4566	intracellular signal transduction
HUE56_19510	COG2205	protein histidine kinase activity
HUE56_19510	COG2202	Pas domain
HUE56_19520	COG3108	Peptidase M15
HUE56_19535	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUE56_19545	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HUE56_19545	COG1648	precorrin-2 dehydrogenase activity
HUE56_19550	COG0175	sulfate reduction
HUE56_19555	COG0175	sulfate reduction
HUE56_19565	COG2814	Major facilitator Superfamily
HUE56_19570	COG0583	DNA-binding transcription factor activity
HUE56_19575	COG0488	(ABC) transporter
HUE56_19580	COG2070	2-Nitropropane dioxygenase
HUE56_19585	COG3706	GGDEF domain
HUE56_19610	COG1410	methionine synthase
HUE56_19610	COG0646	methionine synthase
HUE56_19625	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HUE56_19635	COG2853	Lipoprotein
HUE56_19665	COG0488	(ABC) transporter
HUE56_19670	COG1671	Belongs to the UPF0178 family
HUE56_19685	COG0277	FAD linked oxidase domain protein
HUE56_19690	COG3199	ATP-NAD kinase
HUE56_19695	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HUE56_19700	COG0022	dehydrogenase e1 component
HUE56_19705	COG0596	Alpha beta hydrolase
HUE56_19705	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUE56_19715	COG1063	alcohol dehydrogenase
HUE56_19720	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HUE56_19730	COG0582	viral genome integration into host DNA
HUE56_19765	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HUE56_19775	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
HUE56_19780	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HUE56_19785	COG2205	protein histidine kinase activity
HUE56_19790	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
HUE56_19795	COG2301	Belongs to the HpcH HpaI aldolase family
HUE56_19840	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HUE56_19845	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HUE56_19850	COG0552	protein localization to endoplasmic reticulum
HUE56_19855	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HUE56_19865	COG0121	glutamine amidotransferase
HUE56_19915	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
HUE56_19920	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
HUE56_19935	COG5420	small protein containing a coiled-coil domain
HUE56_19940	COG4231	catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
HUE56_19950	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HUE56_19975	COG1573	uracil-dna glycosylase
HUE56_19980	COG2154	pterin-4-alpha-carbinolamine dehydratase
HUE56_19985	COG4948	Mandelate Racemase Muconate Lactonizing
HUE56_20010	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
HUE56_20015	COG2894	cell division
HUE56_20020	COG0850	regulation of cytokinetic process
HUE56_20025	COG1702	phosphate starvation-inducible protein PhoH
HUE56_20035	COG1999	signal sequence binding
HUE56_20045	COG0356	it plays a direct role in the translocation of protons across the membrane
HUE56_20050	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HUE56_20055	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HUE56_20065	COG3384	dioxygenase
HUE56_20070	COG0784	Response regulator, receiver
HUE56_20070	COG5002	protein histidine kinase activity
HUE56_20075	COG0235	Class ii aldolase
HUE56_20090	COG0437	4 iron, 4 sulfur cluster binding
HUE56_20095	COG3383	formate dehydrogenase (NAD+) activity
HUE56_20120	COG0746	molybdenum cofactor guanylyltransferase activity
HUE56_20125	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HUE56_20145	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HUE56_20150	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUE56_20165	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HUE56_20180	COG2703	oxygen carrier activity
HUE56_20185	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HUE56_20215	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HUE56_20230	COG0612	Peptidase, M16
HUE56_20235	COG0612	Peptidase, M16
HUE56_20245	COG0166	Belongs to the GPI family
HUE56_20265	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HUE56_20275	COG2205	protein histidine kinase activity
HUE56_20280	COG5002	protein histidine kinase activity
HUE56_20285	COG2205	protein histidine kinase activity
HUE56_20285	COG2202	Pas domain
HUE56_20300	COG1686	Belongs to the peptidase S11 family
HUE56_20325	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HUE56_20350	COG1366	Belongs to the anti-sigma-factor antagonist family
HUE56_20355	COG3852	Histidine kinase
HUE56_20400	COG0501	Belongs to the peptidase M48B family
HUE56_20405	COG5508	conserved small protein
HUE56_20410	COG3842	ATPase activity
HUE56_20415	COG0395	ABC-type sugar transport system, permease component
HUE56_20430	COG2205	protein histidine kinase activity
HUE56_20445	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HUE56_20455	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HUE56_20460	COG2962	Rard protein
HUE56_20470	COG1902	pentaerythritol trinitrate reductase activity
HUE56_20525	COG0644	oxidoreductase
HUE56_20530	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HUE56_20540	COG0784	Response regulator, receiver
HUE56_20540	COG5002	protein histidine kinase activity
HUE56_20540	COG2205	protein histidine kinase activity
HUE56_20550	COG1280	lysine exporter protein (LysE YggA)
HUE56_20560	COG1663	tetraacyldisaccharide 4'-kinase activity
HUE56_20565	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HUE56_20565	COG1519	Transferase
HUE56_20570	COG1280	lysine exporter protein (LysE YggA)
HUE56_20575	COG0438	transferase activity, transferring glycosyl groups
HUE56_20585	COG1597	lipid kinase activity
HUE56_20595	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HUE56_20600	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HUE56_20630	COG0628	permease
HUE56_20645	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HUE56_20650	COG2030	dehydratase
HUE56_20655	COG0196	riboflavin kinase activity
HUE56_20665	COG2814	Major facilitator Superfamily
HUE56_20670	COG1285	pathogenesis
HUE56_20700	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HUE56_20710	COG2267	carboxylic ester hydrolase activity
HUE56_20715	COG2873	o-acetylhomoserine
HUE56_20720	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
HUE56_20735	COG0697	spore germination
HUE56_20745	COG0563	adenylate kinase activity
HUE56_20755	COG0200	Binds to the 23S rRNA
HUE56_20760	COG1841	ribosomal large subunit assembly
HUE56_20765	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HUE56_20775	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HUE56_20780	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HUE56_20785	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HUE56_20795	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HUE56_20805	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HUE56_20810	COG0255	Belongs to the universal ribosomal protein uL29 family
HUE56_20815	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HUE56_20820	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HUE56_20825	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HUE56_20830	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HUE56_20835	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HUE56_20840	COG0089	rRNA binding
HUE56_20845	COG0088	Forms part of the polypeptide exit tunnel
HUE56_20855	COG0051	transcription antitermination factor activity, RNA binding
HUE56_20860	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HUE56_20870	COG0049	tRNA binding
HUE56_20880	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HUE56_20885	COG0085	RNA polymerase activity
HUE56_20890	COG0222	ribosome binding
HUE56_20895	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HUE56_20900	COG0081	regulation of translation
HUE56_20905	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HUE56_20925	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HUE56_21015	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUE56_21020	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUE56_21025	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HUE56_21060	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUE56_21060	COG1877	trehalose-phosphatase activity
HUE56_21090	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HUE56_21095	COG0860	N-Acetylmuramoyl-L-alanine amidase
HUE56_21100	COG1530	ribonuclease E activity
HUE56_21110	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HUE56_21125	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HUE56_21135	COG0218	Necessary for normal cell division and for the maintenance of normal septation
HUE56_21140	COG0706	membrane insertase activity
HUE56_21145	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HUE56_21155	COG0230	Belongs to the bacterial ribosomal protein bL34 family
HUE56_21160	COG0335	large ribosomal subunit rRNA binding
HUE56_21165	COG0336	Belongs to the RNA methyltransferase TrmD family
HUE56_21170	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HUE56_21175	COG0228	four-way junction DNA binding
HUE56_21180	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HUE56_21215	COG2171	N-acyltransferase activity
HUE56_21220	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUE56_21240	COG1960	acyl-CoA dehydrogenase activity
HUE56_21250	COG1454	alcohol dehydrogenase
HUE56_21275	COG0247	lactate metabolic process
HUE56_21280	COG0277	FAD linked oxidase domain protein
HUE56_21285	COG0277	FAD linked oxidase domain protein
HUE56_21290	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HUE56_21300	COG0745	RESPONSE REGULATOR receiver
HUE56_21305	COG2205	protein histidine kinase activity
HUE56_21325	COG3108	Peptidase M15
HUE56_21330	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HUE56_21415	COG2022	thiamine diphosphate biosynthetic process
HUE56_21425	COG2022	thiamine diphosphate biosynthetic process
HUE56_21425	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUE56_21430	COG0840	transmembrane signaling receptor activity
HUE56_21430	COG3290	protein histidine kinase activity
HUE56_21435	COG2239	Acts as a magnesium transporter
HUE56_21450	COG0671	phosphoesterase, PA-phosphatase related
HUE56_21550	COG1254	Belongs to the acylphosphatase family
HUE56_21555	COG0318	PFAM AMP-dependent synthetase and ligase
HUE56_21575	COG2719	SpoVR family
HUE56_21580	COG2718	Belongs to the UPF0229 family
HUE56_21585	COG2766	serine protein kinase
HUE56_21590	COG0745	RESPONSE REGULATOR receiver
HUE56_21600	COG3474	cytochrome
HUE56_21610	COG0077	Prephenate dehydratase
HUE56_21640	COG4166	transmembrane transport
HUE56_21645	COG4166	transmembrane transport
HUE56_21650	COG4174	ABC transporter (Permease)
HUE56_21655	COG4239	(ABC) transporter, permease
HUE56_21660	COG4172	Belongs to the ABC transporter superfamily
HUE56_21665	COG1703	isobutyryl-CoA mutase activity
HUE56_21675	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HUE56_21680	COG2137	regulation of response to DNA damage stimulus
HUE56_21685	COG0842	Transport permease protein
HUE56_21690	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUE56_21695	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HUE56_21705	COG3609	addiction module antidote protein, CC2985 family
HUE56_21725	COG3158	transport of potassium into the cell
HUE56_21730	COG3437	response regulator, receiver
HUE56_21730	COG0784	Response regulator, receiver
HUE56_21745	COG0587	DNA-directed DNA polymerase activity
HUE56_21770	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HUE56_21780	COG0181	hydroxymethylbilane synthase activity
HUE56_21810	COG1216	Glycosyl transferase, family 2
HUE56_21810	COG1442	glycosyl transferase family 8
HUE56_21830	COG1842	Phage shock protein A
HUE56_21840	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HUE56_21845	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HUE56_21855	COG0825	malonyl-CoA metabolic process
HUE56_21910	COG2202	Pas domain
HUE56_21910	COG2205	protein histidine kinase activity
HUE56_21925	COG3830	Belongs to the UPF0237 family
HUE56_21925	COG0560	Phosphoserine phosphatase
HUE56_21935	COG1595	DNA-templated transcription, initiation
HUE56_21940	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUE56_21955	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HUE56_21965	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HUE56_21980	COG1695	Transcriptional regulator
HUE56_21990	COG0492	ferredoxin-NADP+ reductase activity
HUE56_21995	COG0601	transmembrane transport
HUE56_22005	COG0444	Belongs to the ABC transporter superfamily
HUE56_22010	COG4608	Belongs to the ABC transporter superfamily
HUE56_22035	COG0583	DNA-binding transcription factor activity
HUE56_22055	COG4566	intracellular signal transduction
HUE56_22070	COG0459	protein refolding
HUE56_22075	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HUE56_22080	COG5425	PFAM Usg family protein
HUE56_22090	COG3772	lysozyme
HUE56_22095	COG1612	heme a metabolic process
HUE56_22100	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUE56_22135	COG3278	Belongs to the heme-copper respiratory oxidase family
HUE56_22145	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HUE56_22165	COG1177	transmembrane transport
HUE56_22185	COG0156	8-amino-7-oxononanoate synthase activity
HUE56_22195	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HUE56_22205	COG0135	phosphoribosylanthranilate isomerase activity
HUE56_22220	COG5265	(ABC) transporter
HUE56_22225	COG0840	transmembrane signaling receptor activity
HUE56_22230	COG1028	Short-chain dehydrogenase reductase Sdr
HUE56_22245	COG1793	dna ligase
HUE56_22255	COG2313	pseudouridylate synthase activity
HUE56_22280	COG1741	Belongs to the pirin family
HUE56_22285	COG0004	ammonium transporteR
HUE56_22290	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HUE56_22295	COG0297	glycogen (starch) synthase activity
HUE56_22315	COG0252	asparaginase activity
HUE56_22335	COG0784	Response regulator, receiver
HUE56_22335	COG3437	response regulator, receiver
HUE56_22350	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HUE56_22355	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HUE56_22360	COG0291	Belongs to the bacterial ribosomal protein bL35 family
HUE56_22365	COG1139	Iron-sulfur cluster binding protein
HUE56_22370	COG0247	lactate metabolic process
HUE56_22380	COG1620	l-lactate permease
HUE56_22385	COG2186	Transcriptional regulator
HUE56_22390	COG2204	response regulator
HUE56_22405	COG0372	Belongs to the citrate synthase family
HUE56_22420	COG2205	protein histidine kinase activity
HUE56_22420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUE56_22435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUE56_22450	COG1737	Transcriptional regulator
HUE56_22465	COG3604	Transcriptional regulator
HUE56_22475	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HUE56_22480	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HUE56_22495	COG3604	Transcriptional regulator
HUE56_22505	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HUE56_22515	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HUE56_22520	COG1063	alcohol dehydrogenase
HUE56_22525	COG0246	Mannitol dehydrogenase
HUE56_22530	COG1802	Transcriptional regulator
HUE56_22535	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HUE56_22555	COG0784	Response regulator, receiver
HUE56_22555	COG2205	protein histidine kinase activity
HUE56_22555	COG5002	protein histidine kinase activity
HUE56_22565	COG3416	Protein conserved in bacteria
HUE56_22575	COG3920	Histidine kinase
HUE56_22585	COG5265	(ABC) transporter
HUE56_22590	COG1032	radical SAM domain protein
HUE56_22610	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HUE56_22620	COG0573	inorganic phosphate transmembrane transporter activity
HUE56_22625	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HUE56_22640	COG0625	glutathione transferase activity
HUE56_22645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUE56_22680	COG2814	Major facilitator Superfamily
HUE56_22695	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HUE56_22715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUE56_22730	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HUE56_22730	COG2885	chlorophyll binding
HUE56_22785	COG1940	carbohydrate kinase activity
HUE56_22805	COG0463	Glycosyl transferase, family 2
HUE56_22825	COG4191	Histidine kinase
HUE56_22825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUE56_22845	COG1858	cytochrome C peroxidase
HUE56_22860	COG4191	Histidine kinase
HUE56_22885	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HUE56_22910	COG3842	ATPase activity
HUE56_22915	COG3842	ATPase activity
HUE56_22935	COG1349	DNA-binding transcription factor activity
HUE56_22985	COG0697	spore germination
HUE56_22995	COG0569	domain protein
HUE56_23000	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HUE56_23055	COG1116	anion transmembrane transporter activity
HUE56_23060	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUE56_23065	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HUE56_23070	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUE56_23080	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HUE56_23090	COG0791	NLP P60 protein
HUE56_23095	COG1648	precorrin-2 dehydrogenase activity
HUE56_23095	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HUE56_23100	COG0243	molybdopterin cofactor binding
HUE56_23110	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUE56_23115	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HUE56_23125	COG1116	anion transmembrane transporter activity
HUE56_23130	COG0656	L-ascorbic acid biosynthetic process
HUE56_23140	COG1752	Esterase of the alpha-beta hydrolase superfamily
HUE56_23170	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HUE56_23175	COG2017	converts alpha-aldose to the beta-anomer
HUE56_23180	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUE56_23185	COG1129	ABC transporter
HUE56_23190	COG1879	ABC-type sugar transport system periplasmic component
HUE56_23230	COG4214	carbohydrate transport
HUE56_23240	COG0840	transmembrane signaling receptor activity
HUE56_23245	COG0129	dihydroxy-acid dehydratase activity
HUE56_23255	COG1966	Carbon starvation protein
HUE56_23260	COG1028	Short-chain dehydrogenase reductase Sdr
HUE56_23280	COG1295	ribonuclease BN
HUE56_23285	COG1794	racemase activity, acting on amino acids and derivatives
HUE56_23290	COG3279	Response regulator of the LytR AlgR family
HUE56_23295	COG3275	phosphorelay sensor kinase activity
HUE56_23305	COG0318	PFAM AMP-dependent synthetase and ligase
HUE56_23315	COG0644	oxidoreductase
HUE56_23325	COG0583	DNA-binding transcription factor activity
HUE56_23340	COG1192	Involved in chromosome partitioning
HUE56_23360	COG3321	synthase
HUE56_23360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUE56_23360	COG0604	alcohol dehydrogenase
HUE56_23360	COG4221	oxidoreductase activity
HUE56_23375	COG1686	Belongs to the peptidase S11 family
HUE56_23385	COG1609	Transcriptional regulator
HUE56_23390	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HUE56_23395	COG1126	abc transporter atp-binding protein
HUE56_23400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUE56_23405	COG0765	amino acid transport
HUE56_23410	COG0765	amino acid transport
HUE56_23415	COG2814	Major facilitator Superfamily
HUE56_23420	COG1487	ribonuclease activity
HUE56_23435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUE56_23440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUE56_23455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUE56_23500	COG1706	bacterial-type flagellum-dependent cell motility
HUE56_23510	COG1256	bacterial-type flagellum assembly
HUE56_23515	COG1749	Flagellar hook protein flgE
HUE56_23525	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HUE56_23535	COG4786	Flagellar basal body rod
HUE56_23540	COG4786	Flagellar basal body rod
HUE56_23545	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
HUE56_23550	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
HUE56_23590	COG1766	The M ring may be actively involved in energy transduction
HUE56_23600	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HUE56_23605	COG1338	Plays a role in the flagellum-specific transport system
HUE56_23615	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HUE56_23630	COG0745	RESPONSE REGULATOR receiver
HUE56_23635	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HUE56_23640	COG5442	Flagellar protein FlaF
HUE56_23645	COG5443	negative regulation of bacterial-type flagellum assembly
HUE56_23665	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HUE56_23690	COG1558	bacterial-type flagellum-dependent cell motility
HUE56_23695	COG1677	Flagellar hook-basal body complex protein FliE
HUE56_23710	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HUE56_23720	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HUE56_23735	COG2814	Major facilitator Superfamily
HUE56_23745	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HUE56_23750	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUE56_23755	COG0351	phosphomethylpyrimidine kinase
HUE56_23760	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
HUE56_23790	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HUE56_23795	COG1845	cytochrome c oxidase, subunit III
HUE56_23800	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HUE56_23805	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HUE56_23810	COG0477	Major facilitator Superfamily
HUE56_23845	COG1988	membrane-bound metal-dependent
HUE56_23870	COG2814	Major facilitator Superfamily
HUE56_23885	COG4178	(ABC) transporter
HUE56_23900	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUE56_23910	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HUE56_23930	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUE56_23955	COG4993	Dehydrogenase
HUE56_23960	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUE56_23970	COG2086	electron transfer activity
HUE56_23985	COG2723	6-phospho-beta-galactosidase activity
HUE56_24010	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HUE56_24015	COG1127	ABC transporter
HUE56_24020	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HUE56_24040	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HUE56_24045	COG0305	Participates in initiation and elongation during chromosome replication
HUE56_24060	COG2010	Cytochrome c
HUE56_24060	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUE56_24080	COG0598	Magnesium transport protein CorA
HUE56_24095	COG0840	transmembrane signaling receptor activity
HUE56_24130	COG0110	maltose O-acetyltransferase activity
HUE56_24140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUE56_24160	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HUE56_24165	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HUE56_24170	COG1127	ABC transporter
HUE56_24175	COG3218	ABC-type transport auxiliary lipoprotein component
HUE56_24175	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HUE56_24195	COG2205	protein histidine kinase activity
HUE56_24195	COG2202	Pas domain
HUE56_24205	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HUE56_24220	COG2703	oxygen carrier activity
HUE56_24235	COG0521	Mo-molybdopterin cofactor biosynthetic process
HUE56_24240	COG0741	lytic transglycosylase activity
HUE56_24245	COG1573	uracil-dna glycosylase
HUE56_24265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUE56_24285	COG0457	Tetratricopeptide repeat
HUE56_24285	COG0859	PFAM glycosyl transferase family 9
HUE56_24295	COG0280	phosphate acetyltransferase
HUE56_24295	COG0281	malic enzyme
HUE56_24300	COG1301	dicarboxylic acid transport
HUE56_24305	COG4191	Histidine kinase
HUE56_24310	COG2204	response regulator
HUE56_24320	COG1640	4-alpha-glucanotransferase
HUE56_24345	COG1024	Enoyl-CoA hydratase
HUE56_24380	COG0318	PFAM AMP-dependent synthetase and ligase
HUE56_24390	COG0625	glutathione transferase activity
HUE56_24410	COG0737	Belongs to the 5'-nucleotidase family
HUE56_24415	COG4191	Histidine kinase
HUE56_24415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUE56_24440	COG1749	Flagellar hook protein flgE
HUE56_24440	COG1749	Flagellar hook protein flgE
HUE56_24455	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
HUE56_24460	COG0366	Alpha amylase catalytic
HUE56_24475	COG1558	bacterial-type flagellum-dependent cell motility
HUE56_24495	COG2226	methyltransferase
HUE56_24500	COG0457	Tetratricopeptide repeat
HUE56_24500	COG0859	PFAM glycosyl transferase family 9
HUE56_24515	COG0859	PFAM glycosyl transferase family 9
HUE56_24515	COG0457	Tetratricopeptide repeat
HUE56_24530	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUE56_24535	COG1028	Short-chain dehydrogenase reductase Sdr
HUE56_24540	COG0318	PFAM AMP-dependent synthetase and ligase
HUE56_24560	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
HUE56_24565	COG2089	acid synthase
HUE56_24585	COG5002	protein histidine kinase activity
HUE56_24600	COG0588	phosphoglycerate mutase activity
HUE56_24605	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HUE56_24620	COG3693	PFAM glycoside hydrolase, family 10
HUE56_24630	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HUE56_24635	COG1045	serine acetyltransferase
HUE56_24655	COG1216	Glycosyl transferase, family 2
HUE56_24660	COG0438	transferase activity, transferring glycosyl groups
HUE56_24665	COG0438	transferase activity, transferring glycosyl groups
HUE56_24680	COG0318	PFAM AMP-dependent synthetase and ligase
HUE56_24685	COG0367	asparagine synthase
HUE56_24690	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HUE56_24715	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HUE56_24720	COG4208	sulfate ABC transporter
HUE56_24730	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HUE56_24780	COG2226	methyltransferase
HUE56_24795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUE56_24805	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HUE56_24810	COG1846	Transcriptional regulator
HUE56_24820	COG3707	response regulator
HUE56_24850	COG3842	ATPase activity
HUE56_24860	COG1840	ABC-type Fe3 transport system, periplasmic component
HUE56_24880	COG1335	isochorismatase
HUE56_24885	COG3791	Glutathione-dependent formaldehyde-activating
HUE56_24895	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUE56_24900	COG0367	asparagine synthase
HUE56_24905	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HUE56_24905	COG1181	Belongs to the D-alanine--D-alanine ligase family
HUE56_24910	COG1363	Peptidase, m42
HUE56_24925	COG5002	protein histidine kinase activity
HUE56_24925	COG0784	Response regulator, receiver
HUE56_24930	COG0745	RESPONSE REGULATOR receiver
HUE56_24945	COG0840	transmembrane signaling receptor activity
HUE56_24955	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HUE56_24965	COG1012	belongs to the aldehyde dehydrogenase family
HUE56_24965	COG2030	dehydratase
HUE56_24975	COG5002	protein histidine kinase activity
HUE56_24975	COG0784	Response regulator, receiver
HUE56_24975	COG2198	Histidine kinase
HUE56_24990	COG1253	flavin adenine dinucleotide binding
HUE56_25005	COG2205	protein histidine kinase activity
HUE56_25005	COG2198	Histidine kinase
HUE56_25005	COG0784	Response regulator, receiver
HUE56_25015	COG1396	sequence-specific DNA binding
HUE56_25020	COG1766	The M ring may be actively involved in energy transduction
HUE56_25030	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HUE56_25035	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HUE56_25040	COG2204	response regulator
HUE56_25045	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HUE56_25065	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HUE56_25100	COG0745	RESPONSE REGULATOR receiver
HUE56_25105	COG2205	protein histidine kinase activity
HUE56_25130	COG0469	pyruvate kinase activity
HUE56_25135	COG3437	response regulator, receiver
HUE56_25135	COG0784	Response regulator, receiver
HUE56_25140	COG5001	Diguanylate cyclase
HUE56_25165	COG1176	ABC-type spermidine putrescine transport system, permease component I
HUE56_25170	COG1177	transmembrane transport
HUE56_25175	COG3842	ATPase activity
HUE56_25180	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HUE56_25185	COG1840	ABC-type Fe3 transport system, periplasmic component
HUE56_25190	COG1176	ABC-type spermidine putrescine transport system, permease component I
HUE56_25195	COG0673	inositol 2-dehydrogenase activity
HUE56_25200	COG0363	glucosamine-6-phosphate deaminase activity
HUE56_25205	COG1175	transmembrane transport
HUE56_25210	COG0395	ABC-type sugar transport system, permease component
HUE56_25220	COG2080	2 iron, 2 sulfur cluster binding
HUE56_25225	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HUE56_25230	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUE56_25245	COG0745	RESPONSE REGULATOR receiver
HUE56_25265	COG1063	alcohol dehydrogenase
HUE56_25275	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HUE56_25280	COG0459	protein refolding
HUE56_25290	COG2133	pyrroloquinoline quinone binding
HUE56_25320	COG0798	PFAM Bile acid sodium symporter
HUE56_25325	COG1454	alcohol dehydrogenase
HUE56_25325	COG1012	belongs to the aldehyde dehydrogenase family
HUE56_25335	COG2814	Major facilitator Superfamily
HUE56_25355	COG5001	Diguanylate cyclase
HUE56_25355	COG4251	negative regulation of phosphorylation
HUE56_25355	COG3706	GGDEF domain
HUE56_25355	COG2203	Gaf domain
HUE56_25360	COG5383	Protein conserved in bacteria
HUE56_25370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUE56_25375	COG0517	IMP dehydrogenase activity
HUE56_25390	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HUE56_25410	COG1446	asparaginase
HUE56_25415	COG2362	D-Aminopeptidase
HUE56_25425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUE56_25435	COG0747	negative chemotaxis
HUE56_25440	COG4172	Belongs to the ABC transporter superfamily
HUE56_25460	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HUE56_25480	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HUE56_25485	COG1984	allophanate hydrolase subunit 2
HUE56_25495	COG3706	GGDEF domain
HUE56_25520	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HUE56_25530	COG0318	PFAM AMP-dependent synthetase and ligase
HUE56_25545	COG2249	NAD(P)H dehydrogenase (quinone) activity
HUE56_25550	COG0574	Belongs to the PEP-utilizing enzyme family
HUE56_25550	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUE56_25570	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HUE56_25600	COG0071	Belongs to the small heat shock protein (HSP20) family
HUE56_25610	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUE56_25615	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HUE56_25620	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUE56_25620	COG0022	dehydrogenase e1 component
HUE56_25625	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUE56_25695	COG3597	protein domain associated with
HUE56_25710	COG4615	Cyclic peptide transporter
HUE56_25765	COG0163	prenyltransferase activity
HUE56_25770	COG0583	DNA-binding transcription factor activity
HUE56_25780	COG2188	Transcriptional regulator
HUE56_25785	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUE56_25840	COG0511	ligase activity, forming carbon-carbon bonds
HUE56_25845	COG0439	Biotin carboxylase
HUE56_25855	COG1984	allophanate hydrolase subunit 2
HUE56_25860	COG1879	ABC-type sugar transport system periplasmic component
HUE56_25865	COG1129	ABC transporter
HUE56_25870	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUE56_25885	COG4584	PFAM Integrase catalytic
HUE56_25970	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HUE56_25995	COG0583	DNA-binding transcription factor activity
HUE56_26005	COG0183	Belongs to the thiolase family
HUE56_26010	COG1028	Short-chain dehydrogenase reductase Sdr
HUE56_26015	COG1024	Enoyl-CoA hydratase
HUE56_26035	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUE56_26065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HUE56_26080	COG1053	succinate dehydrogenase
HUE56_26085	COG1960	acyl-CoA dehydrogenase activity
HUE56_26090	COG1024	Enoyl-CoA hydratase
HUE56_26100	COG1802	Transcriptional regulator
HUE56_26140	COG0559	Belongs to the binding-protein-dependent transport system permease family
HUE56_26170	COG1879	ABC-type sugar transport system periplasmic component
HUE56_26175	COG1129	ABC transporter
HUE56_26185	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUE56_26190	COG3386	PFAM SMP-30 Gluconolaconase
HUE56_26195	COG0277	FAD linked oxidase domain protein
HUE56_26210	COG0583	DNA-binding transcription factor activity
HUE56_26225	COG4670	ketone body catabolic process
HUE56_26235	COG1012	belongs to the aldehyde dehydrogenase family
HUE56_26240	COG1960	acyl-CoA dehydrogenase activity
HUE56_26245	COG0318	PFAM AMP-dependent synthetase and ligase
HUE56_26250	COG2086	electron transfer activity
HUE56_26295	COG3451	type IV secretory pathway VirB4
HUE56_26380	COG5489	Protein of unknown function (DUF736)
HUE56_26415	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HUE56_26435	COG0210	DNA helicase
HUE56_26460	COG2390	Transcriptional regulator
HUE56_26460	COG4584	PFAM Integrase catalytic
HUE56_26465	COG1484	DNA-dependent DNA replication
HUE56_26505	COG1475	DNA binding
HUE56_26515	COG4227	nucleotidyltransferase activity
HUE56_26535	COG1640	4-alpha-glucanotransferase
HUE56_26555	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HUE56_26560	COG0366	Alpha amylase catalytic
HUE56_26580	COG2885	chlorophyll binding
HUE56_26580	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HUE56_26585	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HUE56_26590	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HUE56_26595	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HUE56_26600	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HUE56_26620	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HUE56_26625	COG0583	DNA-binding transcription factor activity
HUE56_26630	COG0625	glutathione transferase activity
HUE56_26660	COG0411	ABC transporter
HUE56_26700	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HUE56_26705	COG3383	formate dehydrogenase (NAD+) activity
HUE56_26720	COG0583	DNA-binding transcription factor activity
HUE56_26750	COG2205	protein histidine kinase activity
HUE56_26750	COG2198	Histidine kinase
HUE56_26750	COG0784	Response regulator, receiver
HUE56_26775	COG1475	DNA binding
HUE56_26780	COG1192	Involved in chromosome partitioning
HUE56_26805	COG2902	Dehydrogenase
HUE56_26825	COG0583	DNA-binding transcription factor activity
HUE56_26830	COG2205	protein histidine kinase activity
HUE56_26855	COG1960	acyl-CoA dehydrogenase activity
HUE56_26860	COG0183	Belongs to the thiolase family
HUE56_26865	COG1960	acyl-CoA dehydrogenase activity
HUE56_26870	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUE56_26875	COG1024	Enoyl-CoA hydratase
HUE56_26880	COG4770	biotin carboxylase activity
HUE56_26900	COG2205	protein histidine kinase activity
HUE56_26910	COG0840	transmembrane signaling receptor activity
HUE56_26930	COG1309	transcriptional regulator
HUE56_26935	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUE56_26975	COG0625	glutathione transferase activity
HUE56_26980	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUE56_26990	COG0640	Transcriptional regulator
HUE56_27005	COG0640	Transcriptional regulator
HUE56_27040	COG1902	pentaerythritol trinitrate reductase activity
HUE56_27050	COG3064	Membrane
HUE56_27050	COG4991	sh3 domain protein
HUE56_27050	COG0515	serine threonine protein kinase
HUE56_27055	COG3243	poly(R)-hydroxyalkanoic acid synthase
HUE56_27065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUE56_27075	COG0678	peroxiredoxin activity
HUE56_27085	COG0148	phosphopyruvate hydratase activity
HUE56_27090	COG0596	Alpha beta hydrolase
HUE56_27095	COG0728	peptidoglycan biosynthetic process
HUE56_27105	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HUE56_27120	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HUE56_27140	COG0546	phosphoglycolate phosphatase activity
HUE56_27180	COG0352	thiamine-phosphate diphosphorylase activity
HUE56_27185	COG1802	Transcriptional regulator
HUE56_27190	COG0469	pyruvate kinase activity
HUE56_27205	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUE56_27205	COG0574	Belongs to the PEP-utilizing enzyme family
HUE56_27215	COG0517	IMP dehydrogenase activity
HUE56_27240	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HUE56_27245	COG0517	IMP dehydrogenase activity
HUE56_27275	COG2351	hydroxyisourate hydrolase activity
HUE56_27280	COG3960	tartronate-semialdehyde synthase activity
HUE56_27290	COG4221	oxidoreductase activity
HUE56_27295	COG2207	Transcriptional regulator
HUE56_27300	COG1414	Transcriptional regulator
HUE56_27305	COG1802	Transcriptional regulator
HUE56_27315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUE56_27320	COG0045	succinate-CoA ligase (ADP-forming) activity
HUE56_27330	COG1414	Transcriptional regulator
HUE56_27335	COG1028	Short-chain dehydrogenase reductase Sdr
HUE56_27335	COG3321	synthase
HUE56_27335	COG0604	alcohol dehydrogenase
HUE56_27370	COG0784	Response regulator, receiver
HUE56_27390	COG0697	spore germination
HUE56_27395	COG0747	negative chemotaxis
HUE56_27400	COG0601	transmembrane transport
HUE56_27405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUE56_27410	COG0444	Belongs to the ABC transporter superfamily
HUE56_27415	COG4608	Belongs to the ABC transporter superfamily
HUE56_27425	COG1666	GTP binding
HUE56_27450	COG2890	protein-(glutamine-N5) methyltransferase activity
HUE56_27460	COG0142	geranyltranstransferase activity
HUE56_27480	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HUE56_27495	COG2860	membrane
HUE56_27505	COG2217	Heavy metal translocating P-type atpase
HUE56_27510	COG0789	Transcriptional regulator
HUE56_27525	COG2814	Major facilitator Superfamily
HUE56_27545	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HUE56_27555	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HUE56_27560	COG0402	S-adenosylhomocysteine deaminase activity
HUE56_27570	COG4603	Belongs to the binding-protein-dependent transport system permease family
HUE56_27590	COG1414	Transcriptional regulator
HUE56_27595	COG3842	ATPase activity
HUE56_27600	COG1176	ABC-type spermidine putrescine transport system, permease component I
HUE56_27605	COG1177	transmembrane transport
HUE56_27630	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
HUE56_27635	COG2223	nitrite transmembrane transporter activity
HUE56_27640	COG3546	catalase activity
HUE56_27665	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
HUE56_27670	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HUE56_27675	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HUE56_27680	COG0295	cytidine deaminase activity
HUE56_27695	COG3411	Ferredoxin
HUE56_27700	COG0697	spore germination
HUE56_27710	COG0559	Belongs to the binding-protein-dependent transport system permease family
HUE56_27750	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HUE56_27780	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HUE56_27795	COG0740	serine-type endopeptidase activity
HUE56_27800	COG0463	Glycosyl transferase, family 2
HUE56_27815	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUE56_27835	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HUE56_27855	COG0308	aminopeptidase N
HUE56_27905	COG0316	Belongs to the HesB IscA family
HUE56_27910	COG0232	Belongs to the dGTPase family. Type 2 subfamily
HUE56_27925	COG1472	Belongs to the glycosyl hydrolase 3 family
HUE56_27930	COG1994	Peptidase M50
HUE56_27935	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HUE56_27940	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HUE56_27945	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HUE56_27950	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HUE56_27955	COG0805	protein transport
HUE56_27960	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HUE56_27980	COG0420	3'-5' exonuclease activity
HUE56_28050	COG1074	ATP-dependent DNA helicase activity
HUE56_28055	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HUE56_28065	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUE56_28110	COG4974	Belongs to the 'phage' integrase family
HUE56_28140	COG1396	sequence-specific DNA binding
HUE56_28150	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HUE56_28175	COG1201	RNA secondary structure unwinding
HUE56_28250	COG1176	ABC-type spermidine putrescine transport system, permease component I
HUE56_28255	COG1177	transmembrane transport
HUE56_28260	COG1028	Short-chain dehydrogenase reductase Sdr
HUE56_28265	COG1802	Transcriptional regulator
HUE56_28270	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HUE56_28275	COG3958	Transketolase
HUE56_28280	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HUE56_28285	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HUE56_28295	COG3842	ATPase activity
HUE56_28305	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUE56_28305	COG1024	Enoyl-CoA hydratase
HUE56_28310	COG1028	Short-chain dehydrogenase reductase Sdr
HUE56_28320	COG3806	Anti-sigma factor
HUE56_28325	COG1595	DNA-templated transcription, initiation
HUE56_28330	COG0477	Major facilitator Superfamily
HUE56_28335	COG1024	Enoyl-CoA hydratase
HUE56_28340	COG0183	Belongs to the thiolase family
HUE56_28345	COG4175	Glycine betaine
HUE56_28350	COG4176	ABC-type proline glycine betaine transport system permease component
HUE56_28370	COG0747	negative chemotaxis
HUE56_28375	COG3437	response regulator, receiver
HUE56_28375	COG0784	Response regulator, receiver
HUE56_28380	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HUE56_28405	COG0737	Belongs to the 5'-nucleotidase family
HUE56_28410	COG0505	Belongs to the CarA family
HUE56_28415	COG2068	MobA-Related Protein
HUE56_28420	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HUE56_28465	COG2358	TRAP transporter, solute receptor (TAXI family
HUE56_28505	COG2770	Histidine kinase
HUE56_28505	COG3437	response regulator, receiver
HUE56_28510	COG3012	SEC-C Motif Domain Protein
HUE56_28520	COG1448	Aminotransferase
HUE56_28530	COG3483	tryptophan 2,3-dioxygenase activity
HUE56_28550	COG1845	cytochrome c oxidase, subunit III
HUE56_28560	COG3256	nitric oxide reductase
HUE56_28565	COG0714	Associated with various cellular activities
HUE56_28575	COG0521	Mo-molybdopterin cofactor biosynthetic process
HUE56_28585	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HUE56_28590	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HUE56_28595	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HUE56_28610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUE56_28650	COG0297	glycogen (starch) synthase activity
HUE56_28665	COG3106	COG3106 Predicted ATPase
HUE56_28670	COG3768	UPF0283 membrane protein
HUE56_28675	COG1741	Belongs to the pirin family
HUE56_28680	COG2205	protein histidine kinase activity
HUE56_28680	COG0784	Response regulator, receiver
HUE56_28685	COG0564	pseudouridine synthase activity
HUE56_28700	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HUE56_28700	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HUE56_28710	COG1028	Short-chain dehydrogenase reductase Sdr
HUE56_28715	COG2271	Major facilitator Superfamily
HUE56_28720	COG1522	sequence-specific DNA binding
HUE56_28760	COG2169	Transcriptional regulator
HUE56_28760	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HUE56_28775	COG1131	(ABC) transporter
HUE56_28790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUE56_28845	COG2273	Hydrolase Family 16
HUE56_28850	COG0772	Belongs to the SEDS family
HUE56_28855	COG3706	GGDEF domain
HUE56_28860	COG1309	transcriptional regulator
HUE56_28880	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HUE56_28885	COG0393	Putative heavy-metal-binding
HUE56_28915	COG1280	lysine exporter protein (LysE YggA)
HUE56_28920	COG2183	response to ionizing radiation
HUE56_28945	COG4251	negative regulation of phosphorylation
HUE56_28950	COG0784	Response regulator, receiver
HUE56_28955	COG2202	Pas domain
HUE56_28955	COG3920	Histidine kinase
HUE56_28960	COG0784	Response regulator, receiver
HUE56_28970	COG2847	Copper chaperone PCu(A)C
HUE56_29005	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUE56_29010	COG4520	surface antigen
HUE56_29020	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUE56_29060	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HUE56_29095	COG4214	carbohydrate transport
HUE56_29110	COG0673	inositol 2-dehydrogenase activity
HUE56_29115	COG0673	inositol 2-dehydrogenase activity
HUE56_29125	COG3485	protocatechuate 3,4-dioxygenase
HUE56_29130	COG2963	transposase activity
HUE56_29140	COG3344	reverse transcriptase
HUE56_29155	COG0583	DNA-binding transcription factor activity
HUE56_29170	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HUE56_29190	COG3344	reverse transcriptase
HUE56_29215	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HUE56_29260	COG4372	Transposase
HUE56_29265	COG3436	PFAM IS66 Orf2 family protein
HUE56_29290	COG1475	DNA binding
HUE56_29310	COG1396	sequence-specific DNA binding
HUE56_29355	COG1475	DNA binding
HUE56_29470	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HUE56_29540	COG0681	Belongs to the peptidase S26 family
HUE56_29660	COG0501	Belongs to the peptidase M48B family
HUE56_29755	COG0583	DNA-binding transcription factor activity
HUE56_29760	COG1063	alcohol dehydrogenase
HUE56_29875	COG2770	Histidine kinase
HUE56_29875	COG3437	response regulator, receiver
HUE56_29890	COG1484	DNA-dependent DNA replication
HUE56_29895	COG4584	PFAM Integrase catalytic
HUE56_29975	COG3436	PFAM IS66 Orf2 family protein
HUE56_30090	COG3436	PFAM IS66 Orf2 family protein
HUE56_30095	COG4372	Transposase
HUE56_30100	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HUE56_30105	COG4957	zinc ion binding
HUE56_30135	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HUE56_30300	COG0586	Pfam SNARE associated Golgi protein
HUE56_30305	COG0671	phosphoesterase, PA-phosphatase related
HUE56_30310	COG0586	Pfam SNARE associated Golgi protein
HUE56_30315	COG5002	protein histidine kinase activity
HUE56_30330	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HUE56_30355	COG1937	Protein conserved in bacteria
HUE56_30380	COG0671	phosphoesterase, PA-phosphatase related
HUE56_30445	COG3258	Cytochrome c
HUE56_30470	COG2132	Multicopper oxidase
HUE56_30490	COG0745	RESPONSE REGULATOR receiver
HUE56_30495	COG0745	RESPONSE REGULATOR receiver