locus-tag	class	description
AZL_000040	COG0237	dephospho-CoA kinase activity
AZL_000050	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AZL_000070	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AZL_000080	COG1331	Highly conserved protein containing a thioredoxin domain
AZL_000120	COG0445	tRNA wobble uridine modification
AZL_000140	COG1192	Involved in chromosome partitioning
AZL_000150	COG1475	DNA binding
AZL_000160	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AZL_000170	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AZL_000180	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AZL_000190	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AZL_000200	COG0280	phosphate acetyltransferase
AZL_000200	COG0281	malic enzyme
AZL_000230	COG5002	protein histidine kinase activity
AZL_000240	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AZL_000250	COG0573	inorganic phosphate transmembrane transporter activity
AZL_000270	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AZL_000280	COG0745	RESPONSE REGULATOR receiver
AZL_000300	COG0670	Belongs to the BI1 family
AZL_000320	COG4181	ATPase activity
AZL_000350	COG0667	Aldo Keto reductase
AZL_000360	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AZL_000390	COG3706	GGDEF domain
AZL_000410	COG0443	Heat shock 70 kDa protein
AZL_000450	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AZL_000490	COG4957	zinc ion binding
AZL_000550	COG4584	PFAM Integrase catalytic
AZL_000560	COG1484	DNA-dependent DNA replication
AZL_000620	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AZL_000640	COG0745	RESPONSE REGULATOR receiver
AZL_000650	COG0642	Histidine kinase
AZL_000680	COG1660	Displays ATPase and GTPase activities
AZL_000690	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AZL_000690	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AZL_000710	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AZL_000740	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AZL_000780	COG0271	Belongs to the BolA IbaG family
AZL_000830	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AZL_000870	COG4974	Belongs to the 'phage' integrase family
AZL_000890	COG2154	pterin-4-alpha-carbinolamine dehydratase
AZL_000910	COG1573	uracil-dna glycosylase
AZL_000930	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AZL_000940	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AZL_000950	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AZL_000960	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AZL_001020	COG2223	nitrite transmembrane transporter activity
AZL_001050	COG0517	IMP dehydrogenase activity
AZL_001050	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AZL_001080	COG1137	ATPase activity
AZL_001090	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AZL_001100	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AZL_001110	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AZL_001120	COG4636	protein conserved in cyanobacteria
AZL_001130	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AZL_001140	COG0527	aspartate kinase activity
AZL_001150	COG2070	2-Nitropropane dioxygenase
AZL_001200	COG2885	chlorophyll binding
AZL_001210	COG1484	DNA-dependent DNA replication
AZL_001220	COG4584	PFAM Integrase catalytic
AZL_001280	COG4964	Belongs to the GSP D family
AZL_001390	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AZL_001400	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AZL_001420	COG2890	protein-(glutamine-N5) methyltransferase activity
AZL_001460	COG0542	response to heat
AZL_001520	COG3162	membrane
AZL_001560	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AZL_001630	COG5001	Diguanylate cyclase
AZL_001650	COG1473	amidohydrolase
AZL_001660	COG0625	glutathione transferase activity
AZL_001670	COG3813	Protein conserved in bacteria
AZL_001680	COG0784	Response regulator, receiver
AZL_001680	COG3437	response regulator, receiver
AZL_001710	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AZL_001770	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AZL_001950	COG3339	Conserved Protein
AZL_001970	COG2423	ornithine cyclodeaminase activity
AZL_001990	COG0776	regulation of translation
AZL_002020	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AZL_002040	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AZL_002060	COG0783	Belongs to the Dps family
AZL_002080	COG0840	transmembrane signaling receptor activity
AZL_002090	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AZL_002110	COG0137	argininosuccinate synthase activity
AZL_002160	COG1272	protein, Hemolysin III
AZL_002330	COG0583	DNA-binding transcription factor activity
AZL_002360	COG1024	Enoyl-CoA hydratase
AZL_002370	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AZL_002370	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AZL_002390	COG0138	bifunctional purine biosynthesis protein purh
AZL_002400	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AZL_002430	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AZL_002440	COG0583	DNA-binding transcription factor activity
AZL_002460	COG0861	Integral membrane protein TerC family
AZL_002470	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AZL_002490	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AZL_002570	COG3660	Nucleoside-diphosphate-sugar epimerase
AZL_002580	COG1522	sequence-specific DNA binding
AZL_002610	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AZL_002620	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AZL_002660	COG3005	denitrification pathway
AZL_002680	COG0243	molybdopterin cofactor binding
AZL_002720	COG0642	Histidine kinase
AZL_002760	COG2318	DinB family
AZL_002770	COG1674	ftsk spoiiie
AZL_002790	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AZL_002810	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AZL_002820	COG1238	metal cluster binding
AZL_002930	COG0539	negative regulation of cytoplasmic translation
AZL_002950	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AZL_002970	COG0574	Belongs to the PEP-utilizing enzyme family
AZL_002970	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AZL_003030	COG0583	DNA-binding transcription factor activity
AZL_003040	COG0297	glycogen (starch) synthase activity
AZL_003050	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AZL_003060	COG0004	ammonium transporteR
AZL_003070	COG1741	Belongs to the pirin family
AZL_003100	COG2313	pseudouridylate synthase activity
AZL_003120	COG1793	dna ligase
AZL_003180	COG1028	Short-chain dehydrogenase reductase Sdr
AZL_003210	COG0156	8-amino-7-oxononanoate synthase activity
AZL_003230	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AZL_003240	COG3706	GGDEF domain
AZL_003240	COG0745	RESPONSE REGULATOR receiver
AZL_003250	COG0135	phosphoribosylanthranilate isomerase activity
AZL_003280	COG5265	(ABC) transporter
AZL_003290	COG0840	transmembrane signaling receptor activity
AZL_003300	COG1176	ABC-type spermidine putrescine transport system, permease component I
AZL_003310	COG1177	transmembrane transport
AZL_003340	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AZL_003350	COG3278	Belongs to the heme-copper respiratory oxidase family
AZL_003400	COG2217	Heavy metal translocating P-type atpase
AZL_003420	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AZL_003430	COG1612	heme a metabolic process
AZL_003440	COG3772	lysozyme
AZL_003450	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AZL_003460	COG0459	protein refolding
AZL_003490	COG4566	intracellular signal transduction
AZL_003520	COG0583	DNA-binding transcription factor activity
AZL_003590	COG4608	Belongs to the ABC transporter superfamily
AZL_003600	COG0444	Belongs to the ABC transporter superfamily
AZL_003620	COG0601	transmembrane transport
AZL_003630	COG0492	ferredoxin-NADP+ reductase activity
AZL_003650	COG1695	Transcriptional regulator
AZL_003680	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AZL_003700	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AZL_003730	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AZL_003740	COG1595	DNA-templated transcription, initiation
AZL_003790	COG2205	protein histidine kinase activity
AZL_003790	COG2202	Pas domain
AZL_003830	COG0625	glutathione transferase activity
AZL_003840	COG0456	acetyltransferase
AZL_003840	COG0454	-acetyltransferase
AZL_003880	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AZL_003890	COG0825	malonyl-CoA metabolic process
AZL_003910	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AZL_003920	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AZL_003930	COG1842	Phage shock protein A
AZL_003950	COG1983	PspC domain protein
AZL_003980	COG1216	Glycosyl transferase, family 2
AZL_003980	COG1442	glycosyl transferase family 8
AZL_004040	COG0181	hydroxymethylbilane synthase activity
AZL_004060	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AZL_004090	COG0587	DNA-directed DNA polymerase activity
AZL_004120	COG3437	response regulator, receiver
AZL_004120	COG0784	Response regulator, receiver
AZL_004130	COG3158	transport of potassium into the cell
AZL_004160	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AZL_004170	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AZL_004180	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AZL_004190	COG0842	Transport permease protein
AZL_004200	COG2137	regulation of response to DNA damage stimulus
AZL_004210	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AZL_004230	COG1703	isobutyryl-CoA mutase activity
AZL_004240	COG4172	Belongs to the ABC transporter superfamily
AZL_004250	COG4239	(ABC) transporter, permease
AZL_004260	COG4174	ABC transporter (Permease)
AZL_004270	COG4166	transmembrane transport
AZL_004280	COG4166	transmembrane transport
AZL_004340	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AZL_004350	COG3474	cytochrome
AZL_004380	COG2766	serine protein kinase
AZL_004390	COG2718	Belongs to the UPF0229 family
AZL_004400	COG2719	SpoVR family
AZL_004410	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AZL_004440	COG0318	PFAM AMP-dependent synthetase and ligase
AZL_004450	COG1254	Belongs to the acylphosphatase family
AZL_004510	COG2239	Acts as a magnesium transporter
AZL_004520	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZL_004520	COG2022	thiamine diphosphate biosynthetic process
AZL_004540	COG2022	thiamine diphosphate biosynthetic process
AZL_004640	COG4372	Transposase
AZL_004650	COG4372	Transposase
AZL_004660	COG3436	PFAM IS66 Orf2 family protein
AZL_004680	COG1484	DNA-dependent DNA replication
AZL_004700	COG4584	PFAM Integrase catalytic
AZL_004730	COG4717	serine-type aminopeptidase activity
AZL_004740	COG0420	3'-5' exonuclease activity
AZL_004770	COG0803	Belongs to the bacterial solute-binding protein 9 family
AZL_004820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AZL_004840	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AZL_004860	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AZL_004870	COG3108	Peptidase M15
AZL_004880	COG2003	Belongs to the UPF0758 family
AZL_004900	COG0642	Histidine kinase
AZL_004910	COG0745	RESPONSE REGULATOR receiver
AZL_004920	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AZL_004930	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AZL_004960	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AZL_004970	COG0277	FAD linked oxidase domain protein
AZL_004980	COG0277	FAD linked oxidase domain protein
AZL_004990	COG0247	lactate metabolic process
AZL_005030	COG1454	alcohol dehydrogenase
AZL_005040	COG1960	acyl-CoA dehydrogenase activity
AZL_005080	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AZL_005090	COG2171	N-acyltransferase activity
AZL_005150	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AZL_005160	COG0228	four-way junction DNA binding
AZL_005170	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AZL_005180	COG0336	Belongs to the RNA methyltransferase TrmD family
AZL_005190	COG0335	large ribosomal subunit rRNA binding
AZL_005200	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AZL_005220	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AZL_005230	COG0706	membrane insertase activity
AZL_005240	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AZL_005260	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AZL_005280	COG0598	Magnesium transport protein CorA
AZL_005290	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AZL_005310	COG1530	ribonuclease E activity
AZL_005320	COG0860	N-Acetylmuramoyl-L-alanine amidase
AZL_005330	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AZL_005370	COG1696	Membrane protein involved in D-alanine export
AZL_005410	COG1877	trehalose-phosphatase activity
AZL_005410	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AZL_005480	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AZL_005490	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZL_005500	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZL_005570	COG0411	ABC transporter
AZL_005650	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AZL_005680	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AZL_005690	COG0081	regulation of translation
AZL_005700	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AZL_005710	COG0222	ribosome binding
AZL_005720	COG0085	RNA polymerase activity
AZL_005730	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AZL_005770	COG0049	tRNA binding
AZL_005790	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AZL_005800	COG0051	transcription antitermination factor activity, RNA binding
AZL_005820	COG0088	Forms part of the polypeptide exit tunnel
AZL_005830	COG0089	rRNA binding
AZL_005840	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AZL_005850	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AZL_005860	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AZL_005870	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AZL_005880	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AZL_005890	COG0255	Belongs to the universal ribosomal protein uL29 family
AZL_005900	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AZL_005920	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AZL_005940	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AZL_005950	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AZL_005960	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AZL_005980	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AZL_005990	COG1841	ribosomal large subunit assembly
AZL_006000	COG0200	Binds to the 23S rRNA
AZL_006020	COG0563	adenylate kinase activity
AZL_006030	COG2186	Transcriptional regulator
AZL_006040	COG0697	spore germination
AZL_006070	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AZL_006080	COG3842	ATPase activity
AZL_006130	COG2205	protein histidine kinase activity
AZL_006140	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AZL_006210	COG1285	pathogenesis
AZL_006220	COG2814	Major facilitator Superfamily
AZL_006230	COG0196	riboflavin kinase activity
AZL_006240	COG2030	dehydratase
AZL_006250	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AZL_006260	COG2267	carboxylic ester hydrolase activity
AZL_006280	COG0628	permease
AZL_006340	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AZL_006350	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AZL_006370	COG1597	lipid kinase activity
AZL_006390	COG0438	transferase activity, transferring glycosyl groups
AZL_006410	COG1519	Transferase
AZL_006420	COG1663	tetraacyldisaccharide 4'-kinase activity
AZL_006480	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AZL_006490	COG0644	oxidoreductase
AZL_006590	COG1902	pentaerythritol trinitrate reductase activity
AZL_006610	COG2962	Rard protein
AZL_006620	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AZL_006640	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AZL_006670	COG2205	protein histidine kinase activity
AZL_006700	COG0395	ABC-type sugar transport system, permease component
AZL_006710	COG3842	ATPase activity
AZL_006720	COG5508	conserved small protein
AZL_006730	COG0501	Belongs to the peptidase M48B family
AZL_006810	COG4191	Histidine kinase
AZL_006810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZL_006820	COG1366	Belongs to the anti-sigma-factor antagonist family
AZL_006870	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AZL_006920	COG1686	Belongs to the peptidase S11 family
AZL_006930	COG2198	Histidine kinase
AZL_006930	COG5002	protein histidine kinase activity
AZL_006930	COG0784	Response regulator, receiver
AZL_006950	COG2202	Pas domain
AZL_006950	COG2205	protein histidine kinase activity
AZL_006960	COG4191	Histidine kinase
AZL_006970	COG2205	protein histidine kinase activity
AZL_006990	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AZL_007010	COG0166	Belongs to the GPI family
AZL_007020	COG0612	Peptidase, M16
AZL_007030	COG0612	Peptidase, M16
AZL_007130	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AZL_007150	COG0840	transmembrane signaling receptor activity
AZL_007170	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AZL_007200	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AZL_007230	COG0840	transmembrane signaling receptor activity
AZL_007260	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AZL_007270	COG0746	molybdenum cofactor guanylyltransferase activity
AZL_007310	COG3383	formate dehydrogenase (NAD+) activity
AZL_007320	COG0437	4 iron, 4 sulfur cluster binding
AZL_007340	COG0235	Class ii aldolase
AZL_007350	COG5002	protein histidine kinase activity
AZL_007350	COG0784	Response regulator, receiver
AZL_007360	COG3384	dioxygenase
AZL_007370	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AZL_007380	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AZL_007390	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AZL_007400	COG0356	it plays a direct role in the translocation of protons across the membrane
AZL_007420	COG1999	signal sequence binding
AZL_007430	COG0840	transmembrane signaling receptor activity
AZL_007440	COG1702	phosphate starvation-inducible protein PhoH
AZL_007450	COG0850	regulation of cytokinetic process
AZL_007460	COG2894	cell division
AZL_007470	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AZL_007500	COG0840	transmembrane signaling receptor activity
AZL_007500	COG5278	phosphoserine phosphatase activity
AZL_007520	COG4948	Mandelate Racemase Muconate Lactonizing
AZL_007540	COG1573	uracil-dna glycosylase
AZL_007570	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AZL_007590	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AZL_007610	COG4231	catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
AZL_007620	COG5420	small protein containing a coiled-coil domain
AZL_007650	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AZL_007660	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AZL_007760	COG0121	glutamine amidotransferase
AZL_007780	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AZL_007830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AZL_007840	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AZL_007880	COG1999	signal sequence binding
AZL_007910	COG4771	TonB-dependent receptor
AZL_007930	COG1858	cytochrome C peroxidase
AZL_007940	COG3220	belongs to the UPF0276 family
AZL_007970	COG1294	oxidase, subunit
AZL_008090	COG3293	Transposase
AZL_008150	COG0464	growth
AZL_008310	COG1196	nuclear chromosome segregation
AZL_008310	COG0741	lytic transglycosylase activity
AZL_008310	COG0739	heme binding
AZL_008400	COG0740	serine-type endopeptidase activity
AZL_008420	COG1802	Transcriptional regulator
AZL_008420	COG4626	Terminase
AZL_008670	COG0582	viral genome integration into host DNA
AZL_008770	COG0747	negative chemotaxis
AZL_008780	COG0601	transmembrane transport
AZL_008790	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZL_008800	COG0444	Belongs to the ABC transporter superfamily
AZL_008810	COG1124	(ABC) transporter
AZL_008830	COG0552	protein localization to endoplasmic reticulum
AZL_008840	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AZL_008850	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AZL_008940	COG2301	Belongs to the HpcH HpaI aldolase family
AZL_008950	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AZL_008960	COG2205	protein histidine kinase activity
AZL_008970	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AZL_009030	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AZL_009040	COG1063	alcohol dehydrogenase
AZL_009060	COG0596	Alpha beta hydrolase
AZL_009060	COG0508	dehydrogenase complex catalyzes the overall conversion of
AZL_009070	COG0022	dehydrogenase e1 component
AZL_009080	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AZL_009090	COG3199	ATP-NAD kinase
AZL_009100	COG0277	FAD linked oxidase domain protein
AZL_009120	COG1671	Belongs to the UPF0178 family
AZL_009130	COG0488	(ABC) transporter
AZL_009170	COG2853	Lipoprotein
AZL_009190	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AZL_009220	COG1410	methionine synthase
AZL_009220	COG0646	methionine synthase
AZL_009270	COG3706	GGDEF domain
AZL_009280	COG2070	2-Nitropropane dioxygenase
AZL_009290	COG0488	(ABC) transporter
AZL_009310	COG1966	Carbon starvation protein
AZL_009330	COG0175	sulfate reduction
AZL_009340	COG0175	sulfate reduction
AZL_009350	COG1648	precorrin-2 dehydrogenase activity
AZL_009350	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AZL_009370	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AZL_009400	COG3108	Peptidase M15
AZL_009420	COG2205	protein histidine kinase activity
AZL_009420	COG2202	Pas domain
AZL_009430	COG4566	intracellular signal transduction
AZL_009480	COG0243	molybdopterin cofactor binding
AZL_009490	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AZL_009490	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AZL_009510	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AZL_009540	COG0612	Peptidase, M16
AZL_009590	COG0483	inositol monophosphate 1-phosphatase activity
AZL_009600	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AZL_009630	COG0730	response to heat
AZL_009640	COG0352	thiamine-phosphate diphosphorylase activity
AZL_009650	COG1830	Aldolase
AZL_009690	COG0840	transmembrane signaling receptor activity
AZL_009740	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AZL_009750	COG1692	metallophosphoesterase
AZL_009760	COG0217	transcriptional regulatory protein
AZL_009780	COG0632	four-way junction helicase activity
AZL_009790	COG2255	four-way junction helicase activity
AZL_009800	COG0824	Thioesterase
AZL_009820	COG0848	biopolymer transport protein
AZL_009850	COG2885	chlorophyll binding
AZL_009870	COG0037	tRNA processing
AZL_009880	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AZL_009890	COG3609	addiction module antidote protein, CC2985 family
AZL_009910	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AZL_009920	COG1295	ribonuclease BN
AZL_009950	COG0259	pyridoxamine-phosphate oxidase activity
AZL_009970	COG0840	transmembrane signaling receptor activity
AZL_010000	COG0840	transmembrane signaling receptor activity
AZL_010010	COG2153	protein acetylation
AZL_010040	COG3685	Protein conserved in bacteria
AZL_010070	COG4957	zinc ion binding
AZL_010080	COG0698	ribose 5-phosphate isomerase
AZL_010090	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AZL_010100	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AZL_010110	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AZL_010140	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AZL_010150	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AZL_010160	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AZL_010160	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AZL_010180	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AZL_010180	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AZL_010220	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AZL_010230	COG0416	fatty acid biosynthetic process
AZL_010240	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AZL_010250	COG0776	regulation of translation
AZL_010330	COG3293	Transposase
AZL_010450	COG1764	response to oxidative stress
AZL_010460	COG1846	Transcriptional regulator
AZL_010470	COG0456	acetyltransferase
AZL_010480	COG2890	protein-(glutamine-N5) methyltransferase activity
AZL_010490	COG1393	Belongs to the ArsC family
AZL_010500	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AZL_010520	COG1403	HNH endonuclease
AZL_010530	COG0697	spore germination
AZL_010580	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AZL_010670	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AZL_010680	COG0860	N-Acetylmuramoyl-L-alanine amidase
AZL_010680	COG3409	Peptidoglycan-binding domain 1 protein
AZL_010690	COG3108	Peptidase M15
AZL_010700	COG1396	sequence-specific DNA binding
AZL_010730	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AZL_010740	COG0511	ligase activity, forming carbon-carbon bonds
AZL_010750	COG0439	Biotin carboxylase
AZL_010760	COG0840	transmembrane signaling receptor activity
AZL_010770	COG0745	RESPONSE REGULATOR receiver
AZL_010800	COG0432	Pfam Uncharacterised protein family UPF0047
AZL_010810	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AZL_010830	COG2205	protein histidine kinase activity
AZL_010840	COG0628	permease
AZL_010860	COG0616	signal peptide processing
AZL_010880	COG0745	RESPONSE REGULATOR receiver
AZL_010910	COG0840	transmembrane signaling receptor activity
AZL_010920	COG0436	Aminotransferase
AZL_010940	COG1494	fructose-1,6-bisphosphatase
AZL_010980	COG0303	'Molybdopterin
AZL_010990	COG0583	DNA-binding transcription factor activity
AZL_011010	COG2373	Large extracellular alpha-helical protein
AZL_011020	COG4953	penicillin-binding protein 1C
AZL_011040	COG2132	Multicopper oxidase
AZL_011060	COG1914	H( )-stimulated, divalent metal cation uptake system
AZL_011140	COG0583	DNA-binding transcription factor activity
AZL_011200	COG0583	DNA-binding transcription factor activity
AZL_011270	COG3293	Transposase
AZL_011320	COG3239	Fatty acid desaturase
AZL_011370	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AZL_011370	COG4651	solute:proton antiporter activity
AZL_011390	COG3932	Exopolysaccharide synthesis, ExoD
AZL_011510	COG1192	Involved in chromosome partitioning
AZL_011530	COG2894	cell division
AZL_011580	COG3451	type IV secretory pathway VirB4
AZL_011670	COG1484	DNA-dependent DNA replication
AZL_011680	COG4584	PFAM Integrase catalytic
AZL_011710	COG0519	Catalyzes the synthesis of GMP from XMP
AZL_011710	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AZL_011720	COG1247	-acetyltransferase
AZL_011740	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AZL_011750	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AZL_011770	COG1758	RNA polymerase activity
AZL_011790	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AZL_011800	COG0736	holo-[acyl-carrier-protein] synthase activity
AZL_011810	COG0681	Belongs to the peptidase S26 family
AZL_011820	COG0571	ribonuclease III activity
AZL_011830	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AZL_011860	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
AZL_011960	COG1752	Esterase of the alpha-beta hydrolase superfamily
AZL_012010	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AZL_012030	COG1338	Plays a role in the flagellum-specific transport system
AZL_012050	COG2257	FlhB HrpN YscU SpaS Family
AZL_012060	COG1815	bacterial-type flagellum-dependent cell motility
AZL_012070	COG1558	bacterial-type flagellum-dependent cell motility
AZL_012080	COG1677	Flagellar hook-basal body complex protein FliE
AZL_012100	COG1684	flagellar biosynthetic protein fliR
AZL_012110	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AZL_012180	COG2010	Cytochrome c
AZL_012200	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AZL_012220	COG2076	Multidrug Resistance protein
AZL_012260	COG0312	modulator of DNA gyrase
AZL_012280	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AZL_012290	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AZL_012300	COG0109	protoheme IX farnesyltransferase activity
AZL_012310	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AZL_012320	COG1845	cytochrome c oxidase, subunit III
AZL_012340	COG3346	SURF1 family
AZL_012360	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AZL_012370	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AZL_012380	COG3237	CsbD-like
AZL_012400	COG1742	UPF0060 membrane protein
AZL_012420	COG5001	Diguanylate cyclase
AZL_012430	COG1840	ABC-type Fe3 transport system, periplasmic component
AZL_012440	COG3842	ATPase activity
AZL_012450	COG1132	(ABC) transporter
AZL_012460	COG1752	Esterase of the alpha-beta hydrolase superfamily
AZL_012500	COG1178	ABC-type Fe3 transport system permease component
AZL_012540	COG2226	methyltransferase
AZL_012570	COG1196	nuclear chromosome segregation
AZL_012570	COG0739	heme binding
AZL_012570	COG0741	lytic transglycosylase activity
AZL_012590	COG5487	UPF0391 membrane protein
AZL_012600	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AZL_012610	COG1765	OsmC-like protein
AZL_012650	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AZL_012660	COG0728	peptidoglycan biosynthetic process
AZL_012670	COG2205	protein histidine kinase activity
AZL_012680	COG4191	Histidine kinase
AZL_012710	COG2086	electron transfer activity
AZL_012730	COG0789	Transcriptional regulator
AZL_012740	COG0318	PFAM AMP-dependent synthetase and ligase
AZL_012780	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AZL_012790	COG1360	Flagellar Motor Protein
AZL_012800	COG2308	Evidence 4 Homologs of previously reported genes of
AZL_012890	COG0626	cystathionine gamma-synthase activity
AZL_012900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZL_012910	COG4597	amino acid ABC transporter
AZL_012920	COG0765	amino acid transport
AZL_012930	COG1126	abc transporter atp-binding protein
AZL_012940	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AZL_012960	COG0454	-acetyltransferase
AZL_012960	COG0456	acetyltransferase
AZL_012970	COG2897	thiosulfate sulfurtransferase activity
AZL_012990	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AZL_013000	COG0494	nUDIX hydrolase
AZL_013010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AZL_013040	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AZL_013060	COG1538	Outer membrane efflux protein
AZL_013080	COG0525	valine-tRNA ligase activity
AZL_013090	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AZL_013100	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AZL_013120	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AZL_013130	COG0628	permease
AZL_013150	COG0300	oxidoreductase activity
AZL_013160	COG1846	Transcriptional regulator
AZL_013240	COG1396	sequence-specific DNA binding
AZL_013320	COG0704	Plays a role in the regulation of phosphate uptake
AZL_013350	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AZL_013360	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AZL_013370	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AZL_013410	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AZL_013420	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AZL_013440	COG4191	Histidine kinase
AZL_013500	COG2205	protein histidine kinase activity
AZL_013500	COG0784	Response regulator, receiver
AZL_013500	COG5002	protein histidine kinase activity
AZL_013540	COG1618	nucleotide phosphatase activity, acting on free nucleotides
AZL_013540	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AZL_013560	COG1028	Short-chain dehydrogenase reductase Sdr
AZL_013570	COG0443	Heat shock 70 kDa protein
AZL_013580	COG0489	protein tyrosine kinase activity
AZL_013590	COG0330	HflC and HflK could
AZL_013600	COG0330	HflC and HflK could
AZL_013610	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AZL_013620	COG2197	response regulator
AZL_013630	COG2205	protein histidine kinase activity
AZL_013640	COG0745	RESPONSE REGULATOR receiver
AZL_013660	COG1846	Transcriptional regulator
AZL_013680	COG0149	triose-phosphate isomerase activity
AZL_013770	COG1136	(ABC) transporter
AZL_013780	COG0577	efflux transmembrane transporter activity
AZL_013780	COG1136	(ABC) transporter
AZL_013840	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AZL_013910	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AZL_013920	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AZL_013930	COG0534	Mate efflux family protein
AZL_013950	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AZL_013960	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AZL_013970	COG2813	Specifically methylates the guanine in position
AZL_013980	COG0667	Aldo Keto reductase
AZL_014010	COG1881	PFAM PEBP family protein
AZL_014020	COG5504	Zn-dependent protease
AZL_014030	COG0113	porphobilinogen synthase activity
AZL_014050	COG1597	lipid kinase activity
AZL_014060	COG1024	Enoyl-CoA hydratase
AZL_014070	COG1846	Transcriptional regulator
AZL_014090	COG0559	Belongs to the binding-protein-dependent transport system permease family
AZL_014120	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AZL_014160	COG1028	Short-chain dehydrogenase reductase Sdr
AZL_014170	COG2972	Histidine kinase
AZL_014170	COG0840	transmembrane signaling receptor activity
AZL_014210	COG0058	SHG alpha-glucan phosphorylase activity
AZL_014220	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AZL_014230	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AZL_014240	COG4191	Histidine kinase
AZL_014260	COG1305	Transglutaminase-like
AZL_014270	COG2308	Evidence 4 Homologs of previously reported genes of
AZL_014270	COG2307	Protein conserved in bacteria
AZL_014350	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AZL_014380	COG3784	Protein of unknown function (DUF1318)
AZL_014410	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AZL_014420	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AZL_014450	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AZL_014460	COG2814	Major facilitator Superfamily
AZL_014470	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AZL_014490	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AZL_014530	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AZL_014550	COG3737	Protein of unknown function (DUF498/DUF598)
AZL_014560	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AZL_014570	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AZL_014580	COG1562	ergosterol biosynthetic process
AZL_014590	COG1562	ergosterol biosynthetic process
AZL_014630	COG0583	DNA-binding transcription factor activity
AZL_014640	COG2814	Major facilitator Superfamily
AZL_014650	COG2226	methyltransferase
AZL_014760	COG0714	Associated with various cellular activities
AZL_014780	COG0494	nUDIX hydrolase
AZL_014790	COG0617	tRNA 3'-terminal CCA addition
AZL_014800	COG1028	Short-chain dehydrogenase reductase Sdr
AZL_014820	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AZL_014850	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AZL_014860	COG0629	single-stranded DNA binding
AZL_014920	COG0123	including yeast histone deacetylase and acetoin utilization protein
AZL_014930	COG1116	anion transmembrane transporter activity
AZL_014940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZL_014950	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZL_014980	COG0483	inositol monophosphate 1-phosphatase activity
AZL_015000	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AZL_015010	COG1923	regulation of RNA biosynthetic process
AZL_015030	COG3744	PilT protein domain protein
AZL_015050	COG2204	response regulator
AZL_015110	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AZL_015110	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AZL_015120	COG1058	Belongs to the CinA family
AZL_015120	COG1546	Belongs to the CinA family
AZL_015130	COG1942	4-Oxalocrotonate Tautomerase
AZL_015140	COG2867	negative regulation of translational initiation
AZL_015150	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AZL_015170	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AZL_015190	COG0508	dehydrogenase complex catalyzes the overall conversion of
AZL_015200	COG0022	dehydrogenase e1 component
AZL_015200	COG0508	dehydrogenase complex catalyzes the overall conversion of
AZL_015210	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AZL_015250	COG4149	molybdate abc transporter
AZL_015260	COG0725	ABC transporter, periplasmic molybdate-binding protein
AZL_015280	COG2261	transglycosylase associated protein
AZL_015310	COG2135	peptidase activity
AZL_015330	COG3287	FIST C domain
AZL_015330	COG2200	EAL domain
AZL_015330	COG2199	diguanylate cyclase activity
AZL_015350	COG1218	3'(2'),5'-bisphosphate nucleotidase
AZL_015360	COG2833	Protein of unknown function (DUF455)
AZL_015370	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AZL_015380	COG0328	RNA-DNA hybrid ribonuclease activity
AZL_015390	COG0678	peroxiredoxin activity
AZL_015400	COG2824	Alkylphosphonate utilization operon protein PhnA
AZL_015410	COG4232	protein-disulfide reductase activity
AZL_015420	COG1678	Uncharacterized ACR, COG1678
AZL_015430	COG0314	molybdopterin synthase activity
AZL_015440	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AZL_015460	COG0546	phosphoglycolate phosphatase activity
AZL_015470	COG1763	Mo-molybdopterin cofactor biosynthetic process
AZL_015480	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AZL_015540	COG4120	Belongs to the binding-protein-dependent transport system permease family
AZL_015550	COG0410	ABC transporter
AZL_015620	COG0583	DNA-binding transcription factor activity
AZL_015630	COG0540	Belongs to the ATCase OTCase family
AZL_015640	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AZL_015680	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AZL_015710	COG0776	regulation of translation
AZL_015720	COG4957	zinc ion binding
AZL_015730	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AZL_015790	COG0741	lytic transglycosylase activity
AZL_015800	COG0556	nucleotide-excision repair
AZL_015810	COG2203	Gaf domain
AZL_015810	COG2199	diguanylate cyclase activity
AZL_015850	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AZL_015860	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AZL_015900	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AZL_015910	COG1492	cobalamin metabolic process
AZL_016040	COG0315	cyclic pyranopterin monophosphate synthase activity
AZL_016050	COG0303	'Molybdopterin
AZL_016060	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AZL_016070	COG2333	competence protein COMEC
AZL_016070	COG0658	competence protein
AZL_016080	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AZL_016110	COG4977	sequence-specific DNA binding
AZL_016130	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AZL_016140	COG3494	Protein of unknown function (DUF1009)
AZL_016150	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AZL_016190	COG0750	zinc metalloprotease
AZL_016200	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AZL_016210	COG0575	Belongs to the CDS family
AZL_016220	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AZL_016230	COG0233	cytoplasmic translational termination
AZL_016240	COG0528	UMP kinase activity
AZL_016250	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AZL_016260	COG0052	Belongs to the universal ribosomal protein uS2 family
AZL_016270	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AZL_016280	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AZL_016300	COG4221	oxidoreductase activity
AZL_016310	COG1561	YicC-like family, N-terminal region
AZL_016370	COG0513	Belongs to the DEAD box helicase family
AZL_016390	COG0596	Alpha beta hydrolase
AZL_016410	COG0187	DNA topoisomerase II activity
AZL_016420	COG1607	acyl-coa hydrolase
AZL_016440	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZL_016450	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZL_016510	COG4191	Histidine kinase
AZL_016510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZL_016540	COG3437	response regulator, receiver
AZL_016540	COG0784	Response regulator, receiver
AZL_016560	COG0140	phosphoribosyl-ATP diphosphatase activity
AZL_016620	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AZL_016630	COG2198	Histidine kinase
AZL_016630	COG0643	Histidine kinase
AZL_016640	COG2201	protein-glutamate methylesterase activity
AZL_016650	COG2201	protein-glutamate methylesterase activity
AZL_016680	COG0840	transmembrane signaling receptor activity
AZL_016680	COG3290	protein histidine kinase activity
AZL_016690	COG0840	transmembrane signaling receptor activity
AZL_016710	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AZL_016720	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AZL_016750	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AZL_016770	COG0360	Binds together with S18 to 16S ribosomal RNA
AZL_016780	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AZL_016800	COG0359	binds to the 23S rRNA
AZL_016810	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AZL_016820	COG3706	GGDEF domain
AZL_016830	COG0538	isocitrate dehydrogenase activity
AZL_016850	COG0330	HflC and HflK could
AZL_016900	COG0473	3-isopropylmalate dehydrogenase activity
AZL_016930	COG2814	Major facilitator Superfamily
AZL_016970	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AZL_016990	COG4221	oxidoreductase activity
AZL_017000	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AZL_017050	COG0024	Methionine aminopeptidase
AZL_017090	COG1160	GTP binding
AZL_017120	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AZL_017190	COG3290	protein histidine kinase activity
AZL_017190	COG0840	transmembrane signaling receptor activity
AZL_017200	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AZL_017210	COG5433	transposase activity
AZL_017230	COG1749	Flagellar hook protein flgE
AZL_017360	COG3321	synthase
AZL_017360	COG1028	Short-chain dehydrogenase reductase Sdr
AZL_017360	COG0604	alcohol dehydrogenase
AZL_017380	COG0163	prenyltransferase activity
AZL_017390	COG0288	reversible hydration of carbon dioxide
AZL_017430	COG0205	6-phosphofructokinase activity
AZL_017460	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AZL_017470	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AZL_017480	COG5001	Diguanylate cyclase
AZL_017510	COG0114	fumarate hydratase activity
AZL_017550	COG2951	lytic endotransglycosylase activity
AZL_017600	COG3852	Histidine kinase
AZL_017650	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AZL_017660	COG0840	transmembrane signaling receptor activity
AZL_017690	COG1366	Belongs to the anti-sigma-factor antagonist family
AZL_017700	COG2770	Histidine kinase
AZL_017700	COG2208	phosphoserine phosphatase activity
AZL_017750	COG2814	Major facilitator Superfamily
AZL_017800	COG3501	Rhs element vgr protein
AZL_017940	COG0500	methyltransferase
AZL_017970	COG2885	chlorophyll binding
AZL_018000	COG2172	sigma factor antagonist activity
AZL_018020	COG0745	RESPONSE REGULATOR receiver
AZL_018050	COG0105	UTP biosynthetic process
AZL_018070	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AZL_018090	COG0488	(ABC) transporter
AZL_018100	COG3932	Exopolysaccharide synthesis, ExoD
AZL_018150	COG1686	Belongs to the peptidase S11 family
AZL_018160	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AZL_018170	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AZL_018180	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AZL_018190	COG0084	hydrolase, TatD family'
AZL_018200	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AZL_018200	COG0321	lipoyl(octanoyl) transferase activity
AZL_018210	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AZL_018260	COG5001	Diguanylate cyclase
AZL_018270	COG1381	Involved in DNA repair and RecF pathway recombination
AZL_018280	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AZL_018330	COG4786	Flagellar basal body rod
AZL_018340	COG4786	Flagellar basal body rod
AZL_018360	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AZL_018380	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AZL_018470	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AZL_018480	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AZL_018500	COG1024	Enoyl-CoA hydratase
AZL_018520	COG0758	DNA mediated transformation
AZL_018530	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AZL_018540	COG1024	Enoyl-CoA hydratase
AZL_018550	COG1832	CoA-binding protein
AZL_018580	COG1028	Short-chain dehydrogenase reductase Sdr
AZL_018590	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AZL_018630	COG2207	Transcriptional regulator
AZL_018660	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AZL_018680	COG0745	RESPONSE REGULATOR receiver
AZL_018680	COG3706	GGDEF domain
AZL_018700	COG3447	MASE1 domain protein
AZL_018700	COG5002	protein histidine kinase activity
AZL_018700	COG5001	Diguanylate cyclase
AZL_018730	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AZL_018740	COG1238	metal cluster binding
AZL_018750	COG0203	ribosomal protein L17
AZL_018780	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AZL_018800	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AZL_018810	COG0251	oxidation-reduction process
AZL_018910	COG0582	viral genome integration into host DNA
AZL_018950	COG3293	Transposase
AZL_018980	COG3415	Transposase
AZL_018990	COG3335	DDE superfamily endonuclease
AZL_019100	COG3293	Transposase
AZL_019120	COG3668	Plasmid stabilization system
AZL_019200	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AZL_019200	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AZL_019230	COG2197	response regulator
AZL_019250	COG0154	amidase activity
AZL_019260	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AZL_019290	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AZL_019310	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
AZL_019330	COG3070	regulator of competence-specific genes
AZL_019350	COG0242	peptide deformylase activity
AZL_019360	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AZL_019370	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AZL_019380	COG1201	RNA secondary structure unwinding
AZL_019400	COG0415	Belongs to the DNA photolyase family
AZL_019410	COG0735	belongs to the Fur family
AZL_019420	COG0523	cobalamin synthesis protein
AZL_019440	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AZL_019470	COG2205	protein histidine kinase activity
AZL_019490	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AZL_019500	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AZL_019500	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AZL_019550	COG4251	negative regulation of phosphorylation
AZL_019560	COG0494	nUDIX hydrolase
AZL_019580	COG0497	DNA recombination
AZL_019590	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AZL_019620	COG0745	RESPONSE REGULATOR receiver
AZL_019630	COG0006	proline dipeptidase activity
AZL_019650	COG2264	protein methyltransferase activity
AZL_019670	COG0210	DNA helicase
AZL_019680	COG2197	response regulator
AZL_019690	COG2197	response regulator
AZL_019750	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AZL_019770	COG2910	NAD(P)H-binding
AZL_019800	COG0742	ribosomal rna small subunit methyltransferase
AZL_019810	COG1187	pseudouridine synthase activity
AZL_019820	COG0590	tRNA wobble adenosine to inosine editing
AZL_019840	COG0840	transmembrane signaling receptor activity
AZL_019860	COG1570	exodeoxyribonuclease VII activity
AZL_019870	COG0859	PFAM glycosyl transferase family 9
AZL_019870	COG0457	Tetratricopeptide repeat
AZL_019880	COG0418	dihydroorotase activity
AZL_019930	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AZL_019940	COG0193	aminoacyl-tRNA hydrolase activity
AZL_019980	COG0012	GTP binding
AZL_019990	COG5001	Diguanylate cyclase
AZL_019990	COG3300	MHYT domain
AZL_020010	COG0583	DNA-binding transcription factor activity
AZL_020060	COG2945	thiolester hydrolase activity
AZL_020070	COG1045	serine acetyltransferase
AZL_020090	COG1104	cysteine desulfurase activity
AZL_020120	COG0482	sulfurtransferase activity
AZL_020340	COG1802	Transcriptional regulator
AZL_020340	COG4626	Terminase
AZL_020360	COG0740	serine-type endopeptidase activity
AZL_020440	COG1196	nuclear chromosome segregation
AZL_020440	COG0741	lytic transglycosylase activity
AZL_020440	COG0739	heme binding
AZL_020600	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AZL_020620	COG0531	amino acid
AZL_020630	COG3706	GGDEF domain
AZL_020640	COG3284	Transcriptional regulator
AZL_020670	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AZL_020710	COG3023	N-Acetylmuramoyl-L-alanine amidase
AZL_020730	COG2001	Belongs to the MraZ family
AZL_020740	COG0275	rRNA processing
AZL_020770	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AZL_020790	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AZL_020800	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AZL_020820	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AZL_020830	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AZL_020840	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AZL_020850	COG1181	Belongs to the D-alanine--D-alanine ligase family
AZL_020860	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AZL_020870	COG0849	cell division
AZL_020880	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AZL_020910	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AZL_020950	COG0248	Ppx GppA phosphatase
AZL_020960	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AZL_020970	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AZL_021000	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AZL_021060	COG1183	phosphatidylcholine synthase activity
AZL_021130	COG0354	folic acid binding
AZL_021160	COG0546	phosphoglycolate phosphatase activity
AZL_021170	COG0564	pseudouridine synthase activity
AZL_021180	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AZL_021210	COG1136	(ABC) transporter
AZL_021250	COG0442	prolyl-tRNA aminoacylation
AZL_021290	COG0519	Catalyzes the synthesis of GMP from XMP
AZL_021350	COG1007	ATP synthesis coupled electron transport
AZL_021380	COG0713	ATP synthesis coupled electron transport
AZL_021410	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AZL_021420	COG1034	ATP synthesis coupled electron transport
AZL_021450	COG0649	NAD binding
AZL_021460	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AZL_021470	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AZL_021480	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AZL_021570	COG0583	DNA-binding transcription factor activity
AZL_021600	COG0500	methyltransferase
AZL_021610	COG0140	phosphoribosyl-ATP diphosphatase activity
AZL_021620	COG0704	Plays a role in the regulation of phosphate uptake
AZL_021630	COG2862	Uncharacterized protein family, UPF0114
AZL_021670	COG0768	penicillin binding
AZL_021700	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AZL_021740	COG0028	Belongs to the TPP enzyme family
AZL_021750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZL_021760	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AZL_021770	COG0560	Phosphoserine phosphatase
AZL_021790	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AZL_021820	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AZL_021830	COG0830	nickel cation binding
AZL_021840	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AZL_021850	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AZL_021860	COG0804	urea catabolic process
AZL_021870	COG0832	Belongs to the urease beta subunit family
AZL_021880	COG0831	urea catabolic process
AZL_021890	COG0829	nickel cation binding
AZL_021900	COG2197	response regulator
AZL_021910	COG2197	response regulator
AZL_021920	COG0693	protein deglycase activity
AZL_021950	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AZL_021960	COG0717	Belongs to the dCTP deaminase family
AZL_022170	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AZL_022220	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AZL_022230	COG0557	exoribonuclease II activity
AZL_022240	COG0793	Belongs to the peptidase S41A family
AZL_022250	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AZL_022280	COG1380	Effector of murein hydrolase LrgA
AZL_022290	COG1346	cytolysis
AZL_022300	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AZL_022350	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AZL_022400	COG4191	Histidine kinase
AZL_022400	COG0784	Response regulator, receiver
AZL_022430	COG1131	(ABC) transporter
AZL_022480	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AZL_022510	COG5554	nitrogen fixation
AZL_022560	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AZL_022600	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AZL_022620	COG0745	RESPONSE REGULATOR receiver
AZL_022630	COG2176	DNA-directed DNA polymerase activity
AZL_022630	COG5002	protein histidine kinase activity
AZL_022650	COG2204	response regulator
AZL_022660	COG3852	Histidine kinase
AZL_022670	COG2204	response regulator
AZL_022680	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AZL_022760	COG0752	glycyl-tRNA synthetase alpha subunit
AZL_022770	COG0751	glycine-tRNA ligase activity
AZL_022830	COG3437	response regulator, receiver
AZL_022830	COG2770	Histidine kinase
AZL_022840	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AZL_022860	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AZL_022870	COG0047	phosphoribosylformylglycinamidine synthase activity
AZL_022880	COG0004	ammonium transporteR
AZL_022890	COG0312	modulator of DNA gyrase
AZL_022930	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AZL_022980	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AZL_023000	COG0463	Glycosyl transferase, family 2
AZL_023030	COG0840	transmembrane signaling receptor activity
AZL_023050	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AZL_023060	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
AZL_023070	COG3118	belongs to the thioredoxin family
AZL_023090	COG2835	tetraacyldisaccharide 4'-kinase activity
AZL_023110	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AZL_023130	COG0183	Belongs to the thiolase family
AZL_023140	COG3243	poly(R)-hydroxyalkanoic acid synthase
AZL_023160	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
AZL_023200	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
AZL_023210	COG0842	Transport permease protein
AZL_023220	COG1132	(ABC) transporter
AZL_023230	COG0254	rRNA binding
AZL_023250	COG0071	Belongs to the small heat shock protein (HSP20) family
AZL_023260	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AZL_023270	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AZL_023280	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AZL_023300	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AZL_023320	COG0793	Belongs to the peptidase S41A family
AZL_023330	COG4942	peptidase
AZL_023340	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AZL_023350	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AZL_023360	COG0799	negative regulation of ribosome biogenesis
AZL_023370	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AZL_023400	COG1051	belongs to the nudix hydrolase family
AZL_023420	COG0643	Histidine kinase
AZL_023420	COG2198	Histidine kinase
AZL_023430	COG0835	chemotaxis
AZL_023440	COG2972	Histidine kinase
AZL_023440	COG0840	transmembrane signaling receptor activity
AZL_023460	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AZL_023470	COG2201	protein-glutamate methylesterase activity
AZL_023480	COG0840	transmembrane signaling receptor activity
AZL_023490	COG1366	Belongs to the anti-sigma-factor antagonist family
AZL_023520	COG0745	RESPONSE REGULATOR receiver
AZL_023520	COG3706	GGDEF domain
AZL_023540	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AZL_023550	COG5433	transposase activity
AZL_023560	COG0579	oxidoreductase
AZL_023570	COG0071	Belongs to the small heat shock protein (HSP20) family
AZL_023610	COG0840	transmembrane signaling receptor activity
AZL_023620	COG1322	Protein conserved in bacteria
AZL_023650	COG1028	Short-chain dehydrogenase reductase Sdr
AZL_023750	COG1278	Cold shock
AZL_023790	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AZL_023810	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AZL_023820	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AZL_023850	COG2193	ferroxidase activity
AZL_023870	COG1192	Involved in chromosome partitioning
AZL_023880	COG0009	L-threonylcarbamoyladenylate synthase
AZL_023910	COG0277	FAD linked oxidase domain protein
AZL_023920	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AZL_023940	COG0559	Belongs to the binding-protein-dependent transport system permease family
AZL_023950	COG5433	transposase activity
AZL_023980	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AZL_023990	COG0747	negative chemotaxis
AZL_024030	COG0101	tRNA pseudouridine synthase activity
AZL_024040	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AZL_024050	COG0242	peptide deformylase activity
AZL_024060	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AZL_024090	COG0513	Belongs to the DEAD box helicase family
AZL_024110	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AZL_024120	COG1199	ATP-dependent helicase activity
AZL_024120	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AZL_024150	COG0840	transmembrane signaling receptor activity
AZL_024170	COG1879	ABC-type sugar transport system periplasmic component
AZL_024180	COG0679	Auxin Efflux Carrier
AZL_024200	COG2084	Dehydrogenase
AZL_024210	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AZL_024240	COG1595	DNA-templated transcription, initiation
AZL_024270	COG3706	GGDEF domain
AZL_024270	COG5001	Diguanylate cyclase
AZL_024270	COG2203	Gaf domain
AZL_024270	COG4251	negative regulation of phosphorylation
AZL_024280	COG5002	protein histidine kinase activity
AZL_024280	COG2205	protein histidine kinase activity
AZL_024280	COG0784	Response regulator, receiver
AZL_024310	COG3279	Response regulator of the LytR AlgR family
AZL_024360	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AZL_024380	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AZL_024400	COG2350	Protein conserved in bacteria
AZL_024410	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AZL_024440	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AZL_024450	COG2205	protein histidine kinase activity
AZL_024470	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AZL_024490	COG0586	Pfam SNARE associated Golgi protein
AZL_024520	COG1278	Cold shock
AZL_024570	COG0410	ABC transporter
AZL_024600	COG0559	Belongs to the binding-protein-dependent transport system permease family
AZL_024620	COG3327	negative regulation of DNA-templated transcription, initiation
AZL_024640	COG2871	sodium ion transport
AZL_024650	COG0840	transmembrane signaling receptor activity
AZL_024670	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AZL_024730	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AZL_024740	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AZL_024760	COG0167	dihydroorotate dehydrogenase activity
AZL_024870	COG2032	superoxide dismutase activity
AZL_024880	COG0513	Belongs to the DEAD box helicase family
AZL_024890	COG0625	glutathione transferase activity
AZL_024930	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AZL_024950	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AZL_024980	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AZL_025000	COG4974	Belongs to the 'phage' integrase family
AZL_025010	COG0840	transmembrane signaling receptor activity
AZL_025020	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AZL_025040	COG3012	SEC-C Motif Domain Protein
AZL_025060	COG4191	Histidine kinase
AZL_025100	COG0126	phosphoglycerate kinase activity
AZL_025130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AZL_025150	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AZL_025180	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
AZL_025200	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AZL_025210	COG0582	viral genome integration into host DNA
AZL_025220	COG3311	Transcriptional regulator
AZL_025240	COG4584	PFAM Integrase catalytic
AZL_025250	COG1484	DNA-dependent DNA replication
AZL_025260	COG3335	DDE superfamily endonuclease
AZL_025270	COG3415	Transposase
AZL_025300	COG1546	Belongs to the CinA family
AZL_025300	COG1058	Belongs to the CinA family
AZL_025310	COG1489	DNA binding
AZL_025320	COG0024	Methionine aminopeptidase
AZL_025560	COG1475	DNA binding
AZL_025580	COG0514	ATP-dependent DNA helicase (RecQ)
AZL_025590	COG0494	nUDIX hydrolase
AZL_025610	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AZL_025620	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AZL_025630	COG0653	protein targeting
AZL_025640	COG1970	mechanosensitive ion channel activity
AZL_025670	COG0640	Transcriptional regulator
AZL_025690	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
AZL_025750	COG0039	L-malate dehydrogenase activity
AZL_025760	COG0045	succinate-CoA ligase (ADP-forming) activity
AZL_025810	COG3293	Transposase
AZL_025830	COG4191	Histidine kinase
AZL_025860	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AZL_025880	COG1643	Atp-dependent helicase
AZL_025890	COG1252	NADH dehydrogenase
AZL_025900	COG1309	transcriptional regulator
AZL_025910	COG0481	GTPase activity
AZL_025930	COG0252	asparaginase activity
AZL_025950	COG0583	DNA-binding transcription factor activity
AZL_025960	COG0784	Response regulator, receiver
AZL_025960	COG3437	response regulator, receiver
AZL_025990	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AZL_026000	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AZL_026010	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AZL_026030	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AZL_026050	COG1187	pseudouridine synthase activity
AZL_026060	COG1960	acyl-CoA dehydrogenase activity
AZL_026090	COG0318	PFAM AMP-dependent synthetase and ligase
AZL_026120	COG0306	phosphate transporter
AZL_026130	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AZL_026150	COG2202	Pas domain
AZL_026150	COG2205	protein histidine kinase activity
AZL_026190	COG0584	glycerophosphoryl diester phosphodiesterase
AZL_026200	COG1509	lysine 2,3-aminomutase activity
AZL_026340	COG0745	RESPONSE REGULATOR receiver
AZL_026360	COG1234	tRNA 3'-trailer cleavage
AZL_026410	COG1120	ATPase activity
AZL_026420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AZL_026460	COG0438	transferase activity, transferring glycosyl groups
AZL_026510	COG0492	ferredoxin-NADP+ reductase activity
AZL_026520	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AZL_026540	COG2264	protein methyltransferase activity
AZL_026600	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AZL_026620	COG0745	RESPONSE REGULATOR receiver
AZL_026650	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AZL_026670	COG3842	ATPase activity
AZL_026680	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AZL_026690	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AZL_026700	COG0268	Binds directly to 16S ribosomal RNA
AZL_026710	COG1024	Enoyl-CoA hydratase
AZL_026730	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AZL_026760	COG0477	Major facilitator Superfamily
AZL_026780	COG0840	transmembrane signaling receptor activity
AZL_026790	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AZL_026800	COG0215	cysteine-tRNA ligase activity
AZL_026810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZL_026830	COG0747	negative chemotaxis
AZL_026840	COG4166	transmembrane transport
AZL_026850	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AZL_026880	COG0039	L-malate dehydrogenase activity
AZL_026920	COG0598	Magnesium transport protein CorA
AZL_026930	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AZL_026940	COG1872	DUF167
AZL_026980	COG3415	Transposase
AZL_026990	COG3335	DDE superfamily endonuclease
AZL_027010	COG1715	Restriction endonuclease
AZL_027050	COG0285	dihydrofolate synthase activity
AZL_027060	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AZL_027080	COG0133	tryptophan synthase activity
AZL_027100	COG1278	Cold shock
AZL_027110	COG2204	response regulator
AZL_027120	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AZL_027130	COG0756	dUTP diphosphatase activity
AZL_027140	COG0784	Response regulator, receiver
AZL_027140	COG2205	protein histidine kinase activity
AZL_027140	COG5002	protein histidine kinase activity
AZL_027150	COG2205	protein histidine kinase activity
AZL_027170	COG0802	atpase or kinase
AZL_027190	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AZL_027200	COG2887	Belongs to the helicase family. UvrD subfamily
AZL_027210	COG1074	ATP-dependent DNA helicase activity
AZL_027220	COG3118	belongs to the thioredoxin family
AZL_027260	COG0592	DNA-directed DNA polymerase activity
AZL_027270	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AZL_027280	COG0187	DNA topoisomerase II activity
AZL_027310	COG0154	amidase activity
AZL_027330	COG3547	Transposase (IS116 IS110 IS902 family)
AZL_027350	COG3541	Predicted nucleotidyltransferase
AZL_027420	COG1074	ATP-dependent DNA helicase activity
AZL_027440	COG1518	maintenance of DNA repeat elements
AZL_027440	COG1468	defense response to virus
AZL_027450	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AZL_027480	COG1484	DNA-dependent DNA replication
AZL_027490	COG4584	PFAM Integrase catalytic
AZL_027500	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AZL_027510	COG3436	PFAM IS66 Orf2 family protein
AZL_027520	COG4372	Transposase
AZL_027550	COG4644	lycopene metabolic process
AZL_027590	COG0798	PFAM Bile acid sodium symporter
AZL_027600	COG0431	NADPH-dependent FMN reductase
AZL_027620	COG3335	DDE superfamily endonuclease
AZL_027630	COG3415	Transposase
AZL_027640	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AZL_027690	COG3547	Transposase (IS116 IS110 IS902 family)
AZL_027720	COG2226	methyltransferase
AZL_027730	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AZL_027760	COG2801	Transposase and inactivated derivatives
AZL_027800	COG3436	PFAM IS66 Orf2 family protein
AZL_027820	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AZL_027830	COG3436	PFAM IS66 Orf2 family protein
AZL_027840	COG4372	Transposase
AZL_027850	COG4372	Transposase
AZL_027860	COG3415	Transposase
AZL_027870	COG3335	DDE superfamily endonuclease
AZL_027880	COG4372	Transposase
AZL_027890	COG4584	PFAM Integrase catalytic
AZL_027900	COG1484	DNA-dependent DNA replication
AZL_027920	COG3436	PFAM IS66 Orf2 family protein
AZL_027940	COG0739	heme binding
AZL_027970	COG0386	Belongs to the glutathione peroxidase family
AZL_027980	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AZL_027990	COG4133	protoheme IX ABC transporter activity
AZL_028060	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AZL_028070	COG0792	nuclease activity
AZL_028120	COG0180	Tryptophanyl-tRNA synthetase
AZL_028130	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AZL_028150	COG0840	transmembrane signaling receptor activity
AZL_028160	COG4771	TonB-dependent receptor
AZL_028190	COG0606	chelatase, subunit chli
AZL_028210	COG2391	methyltransferase activity
AZL_028240	COG1420	regulation of RNA biosynthetic process
AZL_028260	COG0745	RESPONSE REGULATOR receiver
AZL_028280	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AZL_028310	COG0730	response to heat
AZL_028340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AZL_028370	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AZL_028410	COG0668	transmembrane transport
AZL_028420	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AZL_028430	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AZL_028440	COG0302	gtp cyclohydrolase
AZL_028450	COG2967	ApaG domain
AZL_028470	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AZL_028480	COG1702	phosphate starvation-inducible protein PhoH
AZL_028500	COG1253	flavin adenine dinucleotide binding
AZL_028510	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AZL_028520	COG1396	sequence-specific DNA binding
AZL_028530	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AZL_028540	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AZL_028550	COG2329	Antibiotic biosynthesis monooxygenase
AZL_028560	COG0779	Required for maturation of 30S ribosomal subunits
AZL_028610	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AZL_028620	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AZL_028630	COG1185	polyribonucleotide nucleotidyltransferase activity
AZL_028660	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AZL_028680	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AZL_028690	COG1138	Cytochrome C-type biogenesis protein
AZL_028700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AZL_028710	COG3088	subunit of a heme lyase
AZL_028720	COG4235	cytochrome complex assembly
AZL_028730	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AZL_028850	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AZL_028860	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AZL_028870	COG4395	Tim44
AZL_028890	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AZL_028900	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AZL_028920	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AZL_a00030	COG1192	Involved in chromosome partitioning
AZL_a00040	COG1475	DNA binding
AZL_a00050	COG0747	negative chemotaxis
AZL_a00080	COG2205	protein histidine kinase activity
AZL_a00080	COG4999	Histidine kinase
AZL_a00080	COG3850	Histidine kinase
AZL_a00080	COG3437	response regulator, receiver
AZL_a00120	COG0583	DNA-binding transcription factor activity
AZL_a00170	COG3383	formate dehydrogenase (NAD+) activity
AZL_a00180	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AZL_a00250	COG0411	ABC transporter
AZL_a00260	COG0410	ABC transporter
AZL_a00310	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AZL_a00320	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AZL_a00330	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AZL_a00340	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AZL_a00350	COG2885	chlorophyll binding
AZL_a00350	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AZL_a00400	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AZL_a00430	COG1640	4-alpha-glucanotransferase
AZL_a00440	COG3293	Transposase
AZL_a00470	COG3293	Transposase
AZL_a00710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZL_a00740	COG0667	Aldo Keto reductase
AZL_a00750	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AZL_a00760	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AZL_a00770	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AZL_a00780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZL_a00840	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AZL_a00860	COG2079	MmgE PrpD family protein
AZL_a00900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZL_a00910	COG1045	serine acetyltransferase
AZL_a00920	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AZL_a00930	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AZL_a00950	COG1396	sequence-specific DNA binding
AZL_a00960	COG2986	histidine ammonia-lyase
AZL_a00980	COG0747	negative chemotaxis
AZL_a00990	COG0601	transmembrane transport
AZL_a01020	COG4608	Belongs to the ABC transporter superfamily
AZL_a01030	COG2423	ornithine cyclodeaminase activity
AZL_a01050	COG0765	amino acid transport
AZL_a01060	COG4597	amino acid ABC transporter
AZL_a01070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZL_a01110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZL_a01120	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZL_a01130	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZL_a01130	COG1116	anion transmembrane transporter activity
AZL_a01140	COG2188	Transcriptional regulator
AZL_a01150	COG2011	ABC-type metal ion transport system permease component
AZL_a01160	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AZL_a01170	COG1464	Belongs to the NlpA lipoprotein family
AZL_a01230	COG1116	anion transmembrane transporter activity
AZL_a01240	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZL_a01260	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZL_a01290	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AZL_a01300	COG0459	protein refolding
AZL_a01330	COG0559	Belongs to the binding-protein-dependent transport system permease family
AZL_a01340	COG0411	ABC transporter
AZL_a01360	COG2072	flavoprotein involved in K transport
AZL_a01380	COG3335	DDE superfamily endonuclease
AZL_a01400	COG3293	Transposase
AZL_a01420	COG2801	Transposase and inactivated derivatives
AZL_a01470	COG3328	transposase activity
AZL_a01490	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AZL_a01520	COG2814	Major facilitator Superfamily
AZL_a01540	COG0745	RESPONSE REGULATOR receiver
AZL_a01770	COG3501	Rhs element vgr protein
AZL_a01910	COG0318	PFAM AMP-dependent synthetase and ligase
AZL_a01930	COG0604	alcohol dehydrogenase
AZL_a01930	COG3321	synthase
AZL_a01940	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AZL_a01960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AZL_a02080	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AZL_a02170	COG5002	protein histidine kinase activity
AZL_a02170	COG3850	Histidine kinase
AZL_a02230	COG1960	acyl-CoA dehydrogenase activity
AZL_a02240	COG0183	Belongs to the thiolase family
AZL_a02250	COG1960	acyl-CoA dehydrogenase activity
AZL_a02260	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AZL_a02270	COG1024	Enoyl-CoA hydratase
AZL_a02310	COG0745	RESPONSE REGULATOR receiver
AZL_a02320	COG2205	protein histidine kinase activity
AZL_a02340	COG0840	transmembrane signaling receptor activity
AZL_a02370	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AZL_a02390	COG1172	Belongs to the binding-protein-dependent transport system permease family
AZL_a02400	COG1129	ABC transporter
AZL_a02410	COG1879	ABC-type sugar transport system periplasmic component
AZL_a02420	COG1984	allophanate hydrolase subunit 2
AZL_a02440	COG0439	Biotin carboxylase
AZL_a02450	COG0511	ligase activity, forming carbon-carbon bonds
AZL_a02460	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AZL_a02490	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AZL_a02520	COG0559	Belongs to the binding-protein-dependent transport system permease family
AZL_a02610	COG3064	Membrane
AZL_a02610	COG4991	sh3 domain protein
AZL_a02610	COG0515	serine threonine protein kinase
AZL_a02620	COG0784	Response regulator, receiver
AZL_a02620	COG4191	Histidine kinase
AZL_a02630	COG3243	poly(R)-hydroxyalkanoic acid synthase
AZL_a02650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZL_a02670	COG0678	peroxiredoxin activity
AZL_a02700	COG0148	phosphopyruvate hydratase activity
AZL_a02710	COG0596	Alpha beta hydrolase
AZL_a02720	COG0728	peptidoglycan biosynthetic process
AZL_a02740	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AZL_a02770	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AZL_a02780	COG3852	Histidine kinase
AZL_a02790	COG2205	protein histidine kinase activity
AZL_a02800	COG0745	RESPONSE REGULATOR receiver
AZL_a02870	COG0455	bacterial-type flagellum organization
AZL_a02890	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AZL_a02900	COG2204	response regulator
AZL_a02910	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AZL_a02920	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AZL_a02940	COG1766	The M ring may be actively involved in energy transduction
AZL_a02950	COG1396	sequence-specific DNA binding
AZL_a02970	COG2198	Histidine kinase
AZL_a02970	COG2205	protein histidine kinase activity
AZL_a02970	COG0784	Response regulator, receiver
AZL_a03000	COG1253	flavin adenine dinucleotide binding
AZL_a03030	COG3833	ABC-type maltose transport systems, permease component
AZL_a03040	COG1840	ABC-type Fe3 transport system, periplasmic component
AZL_a03070	COG3791	Glutathione-dependent formaldehyde-activating
AZL_a03080	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AZL_a03090	COG0784	Response regulator, receiver
AZL_a03090	COG5002	protein histidine kinase activity
AZL_a03100	COG0745	RESPONSE REGULATOR receiver
AZL_a03130	COG0840	transmembrane signaling receptor activity
AZL_a03150	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AZL_a03170	COG2030	dehydratase
AZL_a03170	COG1012	belongs to the aldehyde dehydrogenase family
AZL_a03200	COG2198	Histidine kinase
AZL_a03200	COG5002	protein histidine kinase activity
AZL_a03200	COG0784	Response regulator, receiver
AZL_a03210	COG1304	FMN binding
AZL_a03230	COG0546	phosphoglycolate phosphatase activity
AZL_a03280	COG0352	thiamine-phosphate diphosphorylase activity
AZL_a03290	COG1802	Transcriptional regulator
AZL_a03300	COG0469	pyruvate kinase activity
AZL_a03320	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AZL_a03320	COG0574	Belongs to the PEP-utilizing enzyme family
AZL_a03380	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AZL_a03390	COG0517	IMP dehydrogenase activity
AZL_a03400	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AZL_a03410	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AZL_a03420	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AZL_a03450	COG2351	hydroxyisourate hydrolase activity
AZL_a03460	COG3960	tartronate-semialdehyde synthase activity
AZL_a03470	COG0840	transmembrane signaling receptor activity
AZL_a03500	COG1414	Transcriptional regulator
AZL_a03510	COG1802	Transcriptional regulator
AZL_a03530	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AZL_a03540	COG0045	succinate-CoA ligase (ADP-forming) activity
AZL_a03560	COG1414	Transcriptional regulator
AZL_a03630	COG0784	Response regulator, receiver
AZL_a03670	COG0697	spore germination
AZL_a03680	COG0747	negative chemotaxis
AZL_a03690	COG0601	transmembrane transport
AZL_a03700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZL_a03710	COG0444	Belongs to the ABC transporter superfamily
AZL_a03720	COG4608	Belongs to the ABC transporter superfamily
AZL_a03740	COG1666	GTP binding
AZL_a03780	COG2890	protein-(glutamine-N5) methyltransferase activity
AZL_a03800	COG0142	geranyltranstransferase activity
AZL_a03810	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AZL_a03840	COG2860	membrane
AZL_a03850	COG2217	Heavy metal translocating P-type atpase
AZL_a03860	COG0789	Transcriptional regulator
AZL_a03870	COG2814	Major facilitator Superfamily
AZL_a03900	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AZL_a03920	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AZL_a03930	COG0402	S-adenosylhomocysteine deaminase activity
AZL_a03950	COG4603	Belongs to the binding-protein-dependent transport system permease family
AZL_a03990	COG1414	Transcriptional regulator
AZL_a04000	COG3842	ATPase activity
AZL_a04010	COG1176	ABC-type spermidine putrescine transport system, permease component I
AZL_a04020	COG1177	transmembrane transport
AZL_a04070	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AZL_a04080	COG2223	nitrite transmembrane transporter activity
AZL_a04090	COG3546	catalase activity
AZL_a04140	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AZL_a04150	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AZL_a04160	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AZL_a04170	COG0295	cytidine deaminase activity
AZL_a04200	COG3411	Ferredoxin
AZL_a04210	COG0697	spore germination
AZL_a04230	COG0559	Belongs to the binding-protein-dependent transport system permease family
AZL_a04240	COG0411	ABC transporter
AZL_a04290	COG0740	serine-type endopeptidase activity
AZL_a04300	COG0463	Glycosyl transferase, family 2
AZL_a04330	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AZL_a04360	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AZL_a04380	COG3474	cytochrome
AZL_a04390	COG0308	aminopeptidase N
AZL_a04420	COG0604	alcohol dehydrogenase
AZL_a04450	COG0316	Belongs to the HesB IscA family
AZL_a04460	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AZL_a04490	COG1472	Belongs to the glycosyl hydrolase 3 family
AZL_a04500	COG1994	Peptidase M50
AZL_a04510	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AZL_a04520	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AZL_a04530	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AZL_a04540	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AZL_a04550	COG0805	protein transport
AZL_a04600	COG0420	3'-5' exonuclease activity
AZL_a04610	COG2084	Dehydrogenase
AZL_a04630	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AZL_a04640	COG3958	Transketolase
AZL_a04650	COG3959	Transketolase, thiamine diphosphate binding domain
AZL_a04660	COG1028	Short-chain dehydrogenase reductase Sdr
AZL_a04670	COG0583	DNA-binding transcription factor activity
AZL_a04680	COG0840	transmembrane signaling receptor activity
AZL_a04680	COG2972	Histidine kinase
AZL_a04710	COG2721	sulfolactate sulfo-lyase activity
AZL_a04730	COG2084	Dehydrogenase
AZL_a04740	COG1312	Catalyzes the dehydration of D-mannonate
AZL_a04750	COG2271	Major facilitator Superfamily
AZL_a04760	COG1609	Transcriptional regulator
AZL_a04770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZL_a04780	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZL_a04790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZL_a04790	COG3453	Protein conserved in bacteria
AZL_a04820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZL_a04830	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZL_a04930	COG1126	abc transporter atp-binding protein
AZL_a04990	COG1132	(ABC) transporter
AZL_a05060	COG1366	Belongs to the anti-sigma-factor antagonist family
AZL_a05150	COG3501	Rhs element vgr protein
AZL_a05180	COG2169	Transcriptional regulator
AZL_a05180	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AZL_a05200	COG1131	(ABC) transporter
AZL_a05230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZL_a05310	COG0559	Belongs to the binding-protein-dependent transport system permease family
AZL_a05330	COG0411	ABC transporter
AZL_a05350	COG0772	Belongs to the SEDS family
AZL_a05360	COG3706	GGDEF domain
AZL_a05370	COG1309	transcriptional regulator
AZL_a05410	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AZL_a05420	COG2183	response to ionizing radiation
AZL_a05480	COG0840	transmembrane signaling receptor activity
AZL_a05510	COG1749	Flagellar hook protein flgE
AZL_a05510	COG1749	Flagellar hook protein flgE
AZL_a05550	COG0737	Belongs to the 5'-nucleotidase family
AZL_a05560	COG0625	glutathione transferase activity
AZL_a05580	COG1024	Enoyl-CoA hydratase
AZL_a05600	COG0745	RESPONSE REGULATOR receiver
AZL_a05620	COG1640	4-alpha-glucanotransferase
AZL_a05640	COG4191	Histidine kinase
AZL_a05650	COG1301	dicarboxylic acid transport
AZL_a05660	COG0280	phosphate acetyltransferase
AZL_a05660	COG0281	malic enzyme
AZL_a05720	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AZL_a05790	COG2847	Copper chaperone PCu(A)C
AZL_a05800	COG0784	Response regulator, receiver
AZL_a05820	COG0784	Response regulator, receiver
AZL_a05830	COG4251	negative regulation of phosphorylation
AZL_a05850	COG3335	DDE superfamily endonuclease
AZL_a05860	COG3415	Transposase
AZL_a05880	COG2801	Transposase and inactivated derivatives
AZL_a05910	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AZL_a05960	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AZL_a05980	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AZL_a05990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AZL_a05990	COG1028	Short-chain dehydrogenase reductase Sdr
AZL_a05990	COG0300	oxidoreductase activity
AZL_a05990	COG0318	PFAM AMP-dependent synthetase and ligase
AZL_a05990	COG3321	synthase
AZL_a06010	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AZL_a06010	COG0072	phenylalanine-tRNA ligase activity
AZL_a06030	COG2771	luxR family
AZL_a06040	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AZL_a06050	COG2273	Hydrolase Family 16
AZL_a06050	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AZL_a06100	COG3328	transposase activity
AZL_a06120	COG3135	benzoate transporter
AZL_a06150	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AZL_a06180	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AZL_a06200	COG3436	PFAM IS66 Orf2 family protein
AZL_a06210	COG4372	Transposase
AZL_a06220	COG1484	DNA-dependent DNA replication
AZL_a06250	COG3328	transposase activity
AZL_a06260	COG4372	Transposase
AZL_a06270	COG3436	PFAM IS66 Orf2 family protein
AZL_a06310	COG1028	Short-chain dehydrogenase reductase Sdr
AZL_a06320	COG0179	Fumarylacetoacetate (FAA) hydrolase
AZL_a06330	COG1129	ABC transporter
AZL_a06340	COG4214	carbohydrate transport
AZL_a06380	COG2721	sulfolactate sulfo-lyase activity
AZL_a06390	COG4154	Belongs to the RbsD FucU family
AZL_a06400	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AZL_a06410	COG0366	Alpha amylase catalytic
AZL_a06460	COG2226	methyltransferase
AZL_a06470	COG0457	Tetratricopeptide repeat
AZL_a06470	COG0859	PFAM glycosyl transferase family 9
AZL_a06500	COG0859	PFAM glycosyl transferase family 9
AZL_a06500	COG0457	Tetratricopeptide repeat
AZL_a06530	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AZL_a06540	COG1028	Short-chain dehydrogenase reductase Sdr
AZL_a06590	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AZL_a06600	COG2089	acid synthase
AZL_a06630	COG0784	Response regulator, receiver
AZL_a06630	COG2198	Histidine kinase
AZL_a06630	COG5002	protein histidine kinase activity
AZL_a06650	COG0588	phosphoglycerate mutase activity
AZL_a06660	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AZL_a06690	COG3693	PFAM glycoside hydrolase, family 10
AZL_a06710	COG4638	Rieske (2fe-2S)
AZL_a06720	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AZL_a06730	COG2146	nitrite reductase [NAD(P)H] activity
AZL_a06780	COG0411	ABC transporter
AZL_a06850	COG2271	Major facilitator Superfamily
AZL_a06870	COG0583	DNA-binding transcription factor activity
AZL_a06890	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AZL_a06900	COG1045	serine acetyltransferase
AZL_a06940	COG1215	transferase activity, transferring glycosyl groups
AZL_a06950	COG0438	transferase activity, transferring glycosyl groups
AZL_a06960	COG0438	transferase activity, transferring glycosyl groups
AZL_a06990	COG0318	PFAM AMP-dependent synthetase and ligase
AZL_a07000	COG0367	asparagine synthase
AZL_a07010	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AZL_a07040	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AZL_a07050	COG4208	sulfate ABC transporter
AZL_a07070	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AZL_a07130	COG2226	methyltransferase
AZL_a07170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZL_a07190	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AZL_a07200	COG1846	Transcriptional regulator
AZL_a07250	COG3707	response regulator
AZL_a07270	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AZL_a07300	COG3415	Transposase
AZL_a07310	COG3335	DDE superfamily endonuclease
AZL_a07370	COG1028	Short-chain dehydrogenase reductase Sdr
AZL_a07420	COG3547	Transposase (IS116 IS110 IS902 family)
AZL_a07450	COG2226	methyltransferase
AZL_a07460	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AZL_a07530	COG4584	PFAM Integrase catalytic
AZL_a07540	COG1484	DNA-dependent DNA replication
AZL_a07570	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AZL_a07590	COG1522	sequence-specific DNA binding
AZL_a07600	COG2271	Major facilitator Superfamily
AZL_a07630	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AZL_a07630	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AZL_a07660	COG0564	pseudouridine synthase activity
AZL_a07670	COG0784	Response regulator, receiver
AZL_a07670	COG2205	protein histidine kinase activity
AZL_a07680	COG1741	Belongs to the pirin family
AZL_a07700	COG0789	Transcriptional regulator
AZL_a07710	COG2188	Transcriptional regulator
AZL_a07720	COG4615	Cyclic peptide transporter
AZL_a07740	COG4774	siderophore transport
AZL_a07820	COG1176	ABC-type spermidine putrescine transport system, permease component I
AZL_a07830	COG1177	transmembrane transport
AZL_a07840	COG3842	ATPase activity
AZL_a07850	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AZL_a07860	COG1840	ABC-type Fe3 transport system, periplasmic component
AZL_a07870	COG1176	ABC-type spermidine putrescine transport system, permease component I
AZL_a07880	COG0673	inositol 2-dehydrogenase activity
AZL_a07900	COG0395	ABC-type sugar transport system, permease component
AZL_a07950	COG0745	RESPONSE REGULATOR receiver
AZL_a07970	COG1063	alcohol dehydrogenase
AZL_a08010	COG0798	PFAM Bile acid sodium symporter
AZL_a08020	COG1012	belongs to the aldehyde dehydrogenase family
AZL_a08020	COG1454	alcohol dehydrogenase
AZL_a08070	COG5001	Diguanylate cyclase
AZL_a08070	COG3300	MHYT domain
AZL_a08080	COG5383	Protein conserved in bacteria
AZL_a08110	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
AZL_a08140	COG0601	transmembrane transport
AZL_a08150	COG5433	transposase activity
AZL_a08170	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AZL_a08180	COG0251	oxidation-reduction process
AZL_a08200	COG0444	Belongs to the ABC transporter superfamily
AZL_a08260	COG2362	D-Aminopeptidase
AZL_a08280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZL_a08300	COG0747	negative chemotaxis
AZL_a08310	COG4172	Belongs to the ABC transporter superfamily
AZL_a08340	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AZL_a08350	COG3706	GGDEF domain
AZL_a08370	COG0246	Mannitol dehydrogenase
AZL_a08380	COG1312	Catalyzes the dehydration of D-mannonate
AZL_a08390	COG3622	Belongs to the hyi family
AZL_a08400	COG1929	Belongs to the glycerate kinase type-1 family
AZL_a08410	COG3835	regulator
AZL_a08420	COG0840	transmembrane signaling receptor activity
AZL_a08440	COG3493	citrate carrier protein
AZL_a08460	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AZL_a08500	COG3052	prosthetic group binding
AZL_a08510	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
AZL_a08520	COG0281	malic enzyme
AZL_a08520	COG0280	phosphate acetyltransferase
AZL_a08570	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AZL_a08580	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AZL_a08600	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AZL_a08690	COG2201	protein-glutamate methylesterase activity
AZL_a08710	COG0835	chemotaxis
AZL_a08720	COG0840	transmembrane signaling receptor activity
AZL_a08730	COG0835	chemotaxis
AZL_a08740	COG2198	Histidine kinase
AZL_a08740	COG0643	Histidine kinase
AZL_a08780	COG0251	oxidation-reduction process
AZL_a08820	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AZL_a08860	COG4638	Rieske (2fe-2S)
AZL_a08900	COG0583	DNA-binding transcription factor activity
AZL_a08950	COG0840	transmembrane signaling receptor activity
AZL_a09040	COG0469	pyruvate kinase activity
AZL_a09050	COG1522	sequence-specific DNA binding
AZL_a09170	COG2271	Major facilitator Superfamily
AZL_a09200	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AZL_a09220	COG0446	pyridine nucleotide-disulphide oxidoreductase
AZL_a09310	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AZL_a09370	COG3842	ATPase activity
AZL_a09380	COG0395	ABC-type sugar transport system, permease component
AZL_a09390	COG1176	ABC-type spermidine putrescine transport system, permease component I
AZL_a09420	COG1012	belongs to the aldehyde dehydrogenase family
AZL_a09430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZL_a09450	COG2267	carboxylic ester hydrolase activity
AZL_a09470	COG2188	Transcriptional regulator
AZL_a09480	COG2801	Transposase and inactivated derivatives
AZL_a09490	COG0004	ammonium transporteR
AZL_a09510	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AZL_a09520	COG2218	PFAM glutamate synthase alpha subunit domain protein
AZL_a09530	COG0069	glutamate synthase activity
AZL_a09540	COG0174	glutamine synthetase
AZL_a09550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZL_a09560	COG4311	Sarcosine oxidase, delta subunit
AZL_a09570	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AZL_a09570	COG0446	pyridine nucleotide-disulphide oxidoreductase
AZL_a09600	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AZL_a09610	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AZL_a09620	COG0028	Belongs to the TPP enzyme family
AZL_a09630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZL_a09650	COG0765	amino acid transport
AZL_a09680	COG0583	DNA-binding transcription factor activity
AZL_a09700	COG2207	Transcriptional regulator
AZL_a09730	COG3321	synthase
AZL_a09730	COG1028	Short-chain dehydrogenase reductase Sdr
AZL_a09730	COG0604	alcohol dehydrogenase
AZL_a09910	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AZL_a09920	COG0129	dihydroxy-acid dehydratase activity
AZL_a09930	COG1737	Transcriptional regulator
AZL_a09980	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
AZL_a09990	COG0535	radical SAM domain protein
AZL_a10020	COG1335	isochorismatase
AZL_a10040	COG1732	Glycine betaine
AZL_a10050	COG1174	glycine betaine transport
AZL_a10060	COG1125	glycine betaine transport
AZL_a10070	COG1174	glycine betaine transport
AZL_a10110	COG3008	intermembrane lipid transfer
AZL_a10120	COG2995	paraquat-inducible protein a
AZL_a10130	COG2188	Transcriptional regulator
AZL_a10150	COG0765	amino acid transport
AZL_a10170	COG1126	abc transporter atp-binding protein
AZL_a10190	COG5001	Diguanylate cyclase
AZL_a10230	COG0840	transmembrane signaling receptor activity
AZL_a10260	COG3842	ATPase activity
AZL_a10270	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AZL_a10310	COG0444	Belongs to the ABC transporter superfamily
AZL_a10320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZL_a10330	COG0601	transmembrane transport
AZL_a10360	COG2204	response regulator
AZL_a10370	COG4191	Histidine kinase
AZL_a10390	COG1647	Serine aminopeptidase, S33
AZL_a10420	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AZL_a10470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZL_a10480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AZL_a10520	COG3842	ATPase activity
AZL_a10530	COG1840	ABC-type Fe3 transport system, periplasmic component
AZL_a10580	COG3220	belongs to the UPF0276 family
AZL_a10600	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AZL_a10610	COG0583	DNA-binding transcription factor activity
AZL_a10640	COG1566	PFAM secretion protein HlyD family protein
AZL_a10670	COG3852	Histidine kinase
AZL_a10730	COG1733	regulation of RNA biosynthetic process
AZL_a10770	COG4221	oxidoreductase activity
AZL_a10780	COG2130	NADP-dependent
AZL_a10790	COG0318	PFAM AMP-dependent synthetase and ligase
AZL_a10820	COG1960	acyl-CoA dehydrogenase activity
AZL_a10830	COG1960	acyl-CoA dehydrogenase activity
AZL_a10870	COG0183	Belongs to the thiolase family
AZL_a10880	COG2197	response regulator
AZL_a10890	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AZL_a10920	COG4447	cellulose binding
AZL_a10950	COG0840	transmembrane signaling receptor activity
AZL_a10960	COG3328	transposase activity
AZL_a10970	COG0840	transmembrane signaling receptor activity
AZL_a10980	COG1024	Enoyl-CoA hydratase
AZL_a11050	COG1304	FMN binding
AZL_a11070	COG0163	prenyltransferase activity
AZL_a11080	COG0583	DNA-binding transcription factor activity
AZL_a11100	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZL_a11100	COG1024	Enoyl-CoA hydratase
AZL_a11150	COG2267	carboxylic ester hydrolase activity
AZL_a11160	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AZL_a11170	COG1024	Enoyl-CoA hydratase
AZL_a11210	COG1960	acyl-CoA dehydrogenase activity
AZL_a11240	COG1024	Enoyl-CoA hydratase
AZL_a11250	COG1028	Short-chain dehydrogenase reductase Sdr
AZL_a11270	COG0583	DNA-binding transcription factor activity
AZL_a11280	COG2902	Dehydrogenase
AZL_b00020	COG1802	Transcriptional regulator
AZL_b00020	COG4626	Terminase
AZL_b00050	COG4214	carbohydrate transport
AZL_b00060	COG4213	ABC transporter substrate-binding protein
AZL_b00070	COG2115	Belongs to the xylose isomerase family
AZL_b00080	COG1070	Carbohydrate kinase
AZL_b00090	COG1609	Transcriptional regulator
AZL_b00120	COG2353	YceI-like domain
AZL_b00130	COG0435	Glutathione S-transferase
AZL_b00140	COG0400	carboxylic ester hydrolase activity
AZL_b00230	COG1475	DNA binding
AZL_b00240	COG1192	Involved in chromosome partitioning
AZL_b00250	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AZL_b00270	COG2731	YhcH YjgK YiaL family protein
AZL_b00280	COG2084	Dehydrogenase
AZL_b00290	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AZL_b00300	COG1063	alcohol dehydrogenase
AZL_b00310	COG1028	Short-chain dehydrogenase reductase Sdr
AZL_b00320	COG0583	DNA-binding transcription factor activity
AZL_b00400	COG0577	efflux transmembrane transporter activity
AZL_b00400	COG1136	(ABC) transporter
AZL_b00460	COG0668	transmembrane transport
AZL_b00500	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AZL_b00540	COG4166	transmembrane transport
AZL_b00610	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AZL_b00630	COG3002	Belongs to the UPF0753 family
AZL_b00640	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AZL_b00660	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AZL_b00670	COG0508	dehydrogenase complex catalyzes the overall conversion of
AZL_b00730	COG5433	transposase activity
AZL_b00770	COG2801	Transposase and inactivated derivatives
AZL_b00820	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AZL_b00870	COG1484	DNA-dependent DNA replication
AZL_b00880	COG4584	PFAM Integrase catalytic
AZL_b00920	COG3293	Transposase
AZL_b00950	COG3718	enzyme involved in inositol metabolism
AZL_b00980	COG0673	inositol 2-dehydrogenase activity
AZL_b01000	COG4211	Belongs to the binding-protein-dependent transport system permease family
AZL_b01010	COG1129	ABC transporter
AZL_b01020	COG1879	ABC-type sugar transport system periplasmic component
AZL_b01050	COG3962	Belongs to the TPP enzyme family
AZL_b01060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AZL_b01180	COG3293	Transposase
AZL_b01220	COG1414	Transcriptional regulator
AZL_b01230	COG5433	transposase activity
AZL_b01250	COG5433	transposase activity
AZL_b01270	COG1484	DNA-dependent DNA replication
AZL_b01280	COG4584	PFAM Integrase catalytic
AZL_b01290	COG4372	Transposase
AZL_b01300	COG4372	Transposase
AZL_b01310	COG3436	PFAM IS66 Orf2 family protein
AZL_b01360	COG2801	Transposase and inactivated derivatives
AZL_b01400	COG1028	Short-chain dehydrogenase reductase Sdr
AZL_b01440	COG1053	succinate dehydrogenase
AZL_b01470	COG0022	dehydrogenase e1 component
AZL_b01480	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AZL_b01520	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AZL_b01550	COG1028	Short-chain dehydrogenase reductase Sdr
AZL_b01590	COG2801	Transposase and inactivated derivatives
AZL_b01600	COG2070	2-Nitropropane dioxygenase
AZL_b01610	COG1024	Enoyl-CoA hydratase
AZL_b01630	COG1024	Enoyl-CoA hydratase
AZL_b01670	COG1960	acyl-CoA dehydrogenase activity
AZL_b01680	COG1960	acyl-CoA dehydrogenase activity
AZL_b01790	COG1028	Short-chain dehydrogenase reductase Sdr
AZL_b01820	COG5433	transposase activity
AZL_b01870	COG3436	PFAM IS66 Orf2 family protein
AZL_b01890	COG4372	Transposase
AZL_b01900	COG4372	Transposase
AZL_b01940	COG1960	acyl-CoA dehydrogenase activity
AZL_b01950	COG1960	acyl-CoA dehydrogenase activity
AZL_b01970	COG1960	acyl-CoA dehydrogenase activity
AZL_b02000	COG3547	Transposase (IS116 IS110 IS902 family)
AZL_b02030	COG0183	Belongs to the thiolase family
AZL_b02040	COG0183	Belongs to the thiolase family
AZL_b02080	COG1028	Short-chain dehydrogenase reductase Sdr
AZL_b02100	COG1960	acyl-CoA dehydrogenase activity
AZL_b02110	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AZL_b02120	COG1414	Transcriptional regulator
AZL_b02130	COG1024	Enoyl-CoA hydratase
AZL_b02140	COG1024	Enoyl-CoA hydratase
AZL_b02160	COG0183	Belongs to the thiolase family
AZL_b02170	COG1024	Enoyl-CoA hydratase
AZL_b02170	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZL_b02210	COG1024	Enoyl-CoA hydratase
AZL_b02220	COG1024	Enoyl-CoA hydratase
AZL_b02260	COG1484	DNA-dependent DNA replication
AZL_b02270	COG4584	PFAM Integrase catalytic
AZL_b02320	COG1028	Short-chain dehydrogenase reductase Sdr
AZL_b02360	COG2801	Transposase and inactivated derivatives
AZL_b02400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZL_b02430	COG2186	Transcriptional regulator
AZL_b02440	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AZL_b02460	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AZL_b02470	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZL_b02500	COG1960	acyl-CoA dehydrogenase activity
AZL_b02550	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZL_b02560	COG1116	anion transmembrane transporter activity
AZL_b02570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZL_b02580	COG0583	DNA-binding transcription factor activity
AZL_b02620	COG1116	anion transmembrane transporter activity
AZL_b02650	COG4521	taurine ABC transporter
AZL_b02660	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AZL_b02670	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZL_b02680	COG2175	clavaminate synthase activity
AZL_b02690	COG0745	RESPONSE REGULATOR receiver
AZL_b02700	COG2205	protein histidine kinase activity
AZL_b02710	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AZL_b02720	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AZL_b02730	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AZL_b02780	COG2186	Transcriptional regulator
AZL_b02790	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AZL_b02800	COG2271	Major facilitator Superfamily
AZL_b02810	COG2721	sulfolactate sulfo-lyase activity
AZL_b02830	COG0583	DNA-binding transcription factor activity
AZL_b02840	COG2851	Citrate transporter
AZL_b02910	COG2855	membrane
AZL_b02950	COG4977	sequence-specific DNA binding
AZL_b02980	COG4566	intracellular signal transduction
AZL_b02990	COG0840	transmembrane signaling receptor activity
AZL_b03010	COG0252	asparaginase activity
AZL_b03050	COG0126	phosphoglycerate kinase activity
AZL_b03070	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AZL_b03090	COG0148	phosphopyruvate hydratase activity
AZL_b03100	COG2116	formate transmembrane transporter activity
AZL_b03110	COG1802	Transcriptional regulator
AZL_b03150	COG3052	prosthetic group binding
AZL_b03240	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AZL_b03270	COG0601	transmembrane transport
AZL_b03290	COG0235	Class ii aldolase
AZL_b03300	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AZL_b03310	COG0583	DNA-binding transcription factor activity
AZL_b03320	COG4221	oxidoreductase activity
AZL_b03330	COG1028	Short-chain dehydrogenase reductase Sdr
AZL_b03370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AZL_b03380	COG1454	alcohol dehydrogenase
AZL_b03390	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AZL_b03410	COG2186	Transcriptional regulator
AZL_b03420	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AZL_b03430	COG0583	DNA-binding transcription factor activity
AZL_b03440	COG2814	Major facilitator Superfamily
AZL_b03460	COG3618	amidohydrolase
AZL_b03490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AZL_b03500	COG1609	Transcriptional regulator
AZL_b03510	COG1879	ABC-type sugar transport system periplasmic component
AZL_b03520	COG1172	Belongs to the binding-protein-dependent transport system permease family
AZL_b03540	COG1869	D-ribose catabolic process
AZL_b03580	COG0154	amidase activity
AZL_b03660	COG2814	Major facilitator Superfamily
AZL_b03680	COG1024	Enoyl-CoA hydratase
AZL_b03690	COG1012	belongs to the aldehyde dehydrogenase family
AZL_b03720	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AZL_b03780	COG1802	Transcriptional regulator
AZL_b03810	COG3842	ATPase activity
AZL_b03850	COG1116	anion transmembrane transporter activity
AZL_b03850	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZL_b03890	COG0439	Biotin carboxylase
AZL_b03900	COG3665	Urea carboxylase-associated protein
AZL_b03920	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AZL_b03940	COG1802	Transcriptional regulator
AZL_b04050	COG1760	l-serine dehydratase
AZL_b04060	COG0814	amino acid
AZL_b04070	COG3275	phosphorelay sensor kinase activity
AZL_b04080	COG3279	Response regulator of the LytR AlgR family
AZL_b04090	COG0583	DNA-binding transcription factor activity
AZL_b04130	COG0444	Belongs to the ABC transporter superfamily
AZL_b04140	COG4608	Belongs to the ABC transporter superfamily
AZL_b04150	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AZL_b04160	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AZL_b04170	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AZL_b04180	COG1522	sequence-specific DNA binding
AZL_b04200	COG0251	oxidation-reduction process
AZL_b04220	COG0154	amidase activity
AZL_b04250	COG0411	ABC transporter
AZL_b04300	COG0375	protein maturation
AZL_b04310	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AZL_b04320	COG2116	formate transmembrane transporter activity
AZL_b04330	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AZL_b04350	COG3260	NADH ubiquinone oxidoreductase 20
AZL_b04370	COG3261	NADH dehydrogenase
AZL_b04370	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AZL_b04380	COG0651	ATP synthesis coupled electron transport
AZL_b04390	COG4237	Hydrogenase 4 membrane
AZL_b04400	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AZL_b04410	COG0650	Formate hydrogenlyase subunit 4
AZL_b04420	COG0651	ATP synthesis coupled electron transport
AZL_b04430	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AZL_b04440	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AZL_b04450	COG3383	formate dehydrogenase (NAD+) activity
AZL_b04460	COG0375	protein maturation
AZL_b04470	COG0583	DNA-binding transcription factor activity
AZL_b04520	COG1914	H( )-stimulated, divalent metal cation uptake system
AZL_b04530	COG1321	iron dependent repressor
AZL_b04580	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AZL_b04580	COG1918	ferrous iron import across plasma membrane
AZL_b04600	COG2814	Major facilitator Superfamily
AZL_b04620	COG0588	phosphoglycerate mutase activity
AZL_b04630	COG0840	transmembrane signaling receptor activity
AZL_b04660	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AZL_b04680	COG0437	4 iron, 4 sulfur cluster binding
AZL_b04690	COG2414	aldehyde ferredoxin oxidoreductase
AZL_b04710	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AZL_b04710	COG2111	Na H antiporter
AZL_b04720	COG0651	ATP synthesis coupled electron transport
AZL_b04730	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AZL_b04740	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AZL_b04760	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AZL_b04770	COG0649	NAD binding
AZL_b04830	COG1175	transmembrane transport
AZL_b04850	COG1940	carbohydrate kinase activity
AZL_b04860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZL_b04870	COG0348	domain, Protein
AZL_b04910	COG0025	NhaP-type Na H and K H
AZL_b04940	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AZL_b04960	COG1335	isochorismatase
AZL_b04980	COG2853	Lipoprotein
AZL_b04990	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AZL_b04990	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AZL_b05010	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AZL_b05020	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AZL_b05030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AZL_b05050	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AZL_b05060	COG2190	(PTS) system
AZL_b05060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AZL_b05060	COG1263	PTS System
AZL_b05080	COG3842	ATPase activity
AZL_b05100	COG1176	ABC-type spermidine putrescine transport system, permease component I
AZL_b05110	COG0581	inorganic phosphate transmembrane transporter activity
AZL_b05160	COG4191	Histidine kinase
AZL_b05170	COG1301	dicarboxylic acid transport
AZL_b05180	COG1027	Aspartate ammonia-lyase
AZL_b05190	COG2258	MOSC domain
AZL_b05200	COG0840	transmembrane signaling receptor activity
AZL_b05220	COG0840	transmembrane signaling receptor activity
AZL_b05240	COG3293	Transposase
AZL_b05270	COG5433	transposase activity
AZL_b05290	COG5433	transposase activity
AZL_b05330	COG4584	PFAM Integrase catalytic
AZL_b05340	COG1484	DNA-dependent DNA replication
AZL_b05450	COG3772	lysozyme
AZL_b05460	COG1609	Transcriptional regulator
AZL_b05470	COG3842	ATPase activity
AZL_b05500	COG1177	transmembrane transport
AZL_b05510	COG1234	tRNA 3'-trailer cleavage
AZL_b05540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZL_b05570	COG0431	NADPH-dependent FMN reductase
AZL_b05590	COG0411	ABC transporter
AZL_b05630	COG0410	ABC transporter
AZL_b05650	COG0662	Cupin 2, conserved barrel domain protein
AZL_b05650	COG2207	Transcriptional regulator
AZL_b05660	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AZL_b05670	COG0840	transmembrane signaling receptor activity
AZL_b05720	COG3768	UPF0283 membrane protein
AZL_b05730	COG3106	COG3106 Predicted ATPase
AZL_b05770	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AZL_b05800	COG1349	DNA-binding transcription factor activity
AZL_b05810	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AZL_b05820	COG1879	ABC-type sugar transport system periplasmic component
AZL_b05830	COG1129	ABC transporter
AZL_b05840	COG1172	Belongs to the binding-protein-dependent transport system permease family
AZL_b05850	COG1172	Belongs to the binding-protein-dependent transport system permease family
AZL_b05870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AZL_b05880	COG1069	ribulokinase activity
AZL_b05900	COG2233	PERMEase
AZL_b05930	COG3436	PFAM IS66 Orf2 family protein
AZL_b05950	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AZL_b05970	COG1484	DNA-dependent DNA replication
AZL_b05980	COG4584	PFAM Integrase catalytic
AZL_b06020	COG0840	transmembrane signaling receptor activity
AZL_b06050	COG4372	Transposase
AZL_b06060	COG4372	Transposase
AZL_b06070	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AZL_b06090	COG3436	PFAM IS66 Orf2 family protein
AZL_b06110	COG4372	Transposase
AZL_b06170	COG1028	Short-chain dehydrogenase reductase Sdr
AZL_b06180	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AZL_b06190	COG1012	belongs to the aldehyde dehydrogenase family
AZL_b06200	COG1028	Short-chain dehydrogenase reductase Sdr
AZL_b06230	COG2801	Transposase and inactivated derivatives
AZL_b06260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZL_b06280	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AZL_b06290	COG4566	intracellular signal transduction
AZL_b06300	COG4566	intracellular signal transduction
AZL_b06310	COG4191	Histidine kinase
AZL_c00070	COG2986	histidine ammonia-lyase
AZL_c00080	COG0402	S-adenosylhomocysteine deaminase activity
AZL_c00090	COG1228	amidohydrolase
AZL_c00100	COG2188	Transcriptional regulator
AZL_c00110	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AZL_c00120	COG2723	6-phospho-beta-galactosidase activity
AZL_c00140	COG0739	heme binding
AZL_c00140	COG1196	nuclear chromosome segregation
AZL_c00140	COG0741	lytic transglycosylase activity
AZL_c00170	COG0583	DNA-binding transcription factor activity
AZL_c00200	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AZL_c00210	COG3842	ATPase activity
AZL_c00220	COG2182	Extracellular solute-binding protein
AZL_c00230	COG1176	ABC-type spermidine putrescine transport system, permease component I
AZL_c00260	COG1396	sequence-specific DNA binding
AZL_c00260	COG1917	Cupin 2, conserved barrel domain protein
AZL_c00290	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AZL_c00320	COG0840	transmembrane signaling receptor activity
AZL_c00320	COG2972	Histidine kinase
AZL_c00330	COG0840	transmembrane signaling receptor activity
AZL_c00330	COG2972	Histidine kinase
AZL_c00390	COG0471	metal ion transport
AZL_c00390	COG3273	potassium ion transport
AZL_c00400	COG0840	transmembrane signaling receptor activity
AZL_c00400	COG2972	Histidine kinase
AZL_c00420	COG5433	transposase activity
AZL_c00440	COG2202	Pas domain
AZL_c00440	COG2205	protein histidine kinase activity
AZL_c00450	COG2373	Large extracellular alpha-helical protein
AZL_c00470	COG0183	Belongs to the thiolase family
AZL_c00480	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZL_c00480	COG1024	Enoyl-CoA hydratase
AZL_c00490	COG1960	acyl-CoA dehydrogenase activity
AZL_c00500	COG2197	response regulator
AZL_c00510	COG0517	IMP dehydrogenase activity
AZL_c00510	COG0516	GMP reductase activity
AZL_c00520	COG3047	cAMP biosynthetic process
AZL_c00580	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AZL_c00590	COG1196	nuclear chromosome segregation
AZL_c00630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZL_c00640	COG0174	glutamine synthetase
AZL_c00650	COG1410	methionine synthase
AZL_c00650	COG0646	methionine synthase
AZL_c00660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZL_c00670	COG0765	amino acid transport
AZL_c00680	COG0535	radical SAM domain protein
AZL_c00700	COG3842	ATPase activity
AZL_c00710	COG1176	ABC-type spermidine putrescine transport system, permease component I
AZL_c00720	COG1177	transmembrane transport
AZL_c00740	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AZL_c00780	COG0356	it plays a direct role in the translocation of protons across the membrane
AZL_c00800	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AZL_c00810	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AZL_c00820	COG1012	belongs to the aldehyde dehydrogenase family
AZL_c00830	COG0028	Belongs to the TPP enzyme family
AZL_c00850	COG4178	(ABC) transporter
AZL_c00900	COG5002	protein histidine kinase activity
AZL_c00900	COG5001	Diguanylate cyclase
AZL_c00930	COG2363	Small membrane protein
AZL_c00940	COG0640	Transcriptional regulator
AZL_c00950	COG0425	Belongs to the sulfur carrier protein TusA family
AZL_c00960	COG0123	including yeast histone deacetylase and acetoin utilization protein
AZL_c00990	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AZL_c01010	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AZL_c01070	COG0625	glutathione transferase activity
AZL_c01170	COG4191	Histidine kinase
AZL_c01190	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AZL_c01200	COG2111	Na H antiporter
AZL_c01200	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AZL_c01210	COG1006	Multisubunit Na H antiporter MnhC subunit
AZL_c01220	COG0651	ATP synthesis coupled electron transport
AZL_c01230	COG1863	multisubunit Na H antiporter MnhE subunit
AZL_c01240	COG2212	antiporter activity
AZL_c01250	COG1320	monovalent cation:proton antiporter activity
AZL_c01260	COG2205	protein histidine kinase activity
AZL_c01270	COG0745	RESPONSE REGULATOR receiver
AZL_c01300	COG1136	(ABC) transporter
AZL_c01340	COG1126	abc transporter atp-binding protein
AZL_c01350	COG0765	amino acid transport
AZL_c01360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZL_c01370	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AZL_c01380	COG1285	pathogenesis
AZL_c01400	COG1116	anion transmembrane transporter activity
AZL_c01430	COG0840	transmembrane signaling receptor activity
AZL_c01430	COG2972	Histidine kinase
AZL_c01450	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AZL_c01460	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AZL_c01470	COG0784	Response regulator, receiver
AZL_c01470	COG5002	protein histidine kinase activity
AZL_c01530	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AZL_c01540	COG1309	transcriptional regulator
AZL_c01550	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AZL_c01560	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AZL_c01570	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AZL_c01580	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AZL_c01590	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AZL_c01610	COG3180	Ammonia monooxygenase
AZL_c01630	COG3956	TIGRFAM MazG family protein
AZL_c01650	COG2826	transposase and inactivated derivatives, IS30 family
AZL_c01660	COG1760	l-serine dehydratase
AZL_c01670	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AZL_c01690	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AZL_c01690	COG0446	pyridine nucleotide-disulphide oxidoreductase
AZL_c01790	COG0446	pyridine nucleotide-disulphide oxidoreductase
AZL_c01790	COG1902	pentaerythritol trinitrate reductase activity
AZL_c01800	COG2181	nitrate reductase activity
AZL_c01800	COG0247	lactate metabolic process
AZL_c01830	COG4175	Glycine betaine
AZL_c01840	COG4176	ABC-type proline glycine betaine transport system permease component
AZL_c01960	COG0375	protein maturation
AZL_c01970	COG2204	response regulator
AZL_c02010	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
AZL_c02020	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AZL_c02040	COG0521	Mo-molybdopterin cofactor biosynthetic process
AZL_c02060	COG0714	Associated with various cellular activities
AZL_c02070	COG3256	nitric oxide reductase
AZL_c02090	COG1845	cytochrome c oxidase, subunit III
AZL_c02100	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AZL_c02120	COG3483	tryptophan 2,3-dioxygenase activity
AZL_c02140	COG1448	Aminotransferase
AZL_c02160	COG3012	SEC-C Motif Domain Protein
AZL_c02170	COG3437	response regulator, receiver
AZL_c02170	COG2770	Histidine kinase
AZL_c02310	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AZL_c02320	COG2068	MobA-Related Protein
AZL_c02330	COG0505	Belongs to the CarA family
AZL_c02340	COG0737	Belongs to the 5'-nucleotidase family
AZL_c02390	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AZL_c02400	COG3437	response regulator, receiver
AZL_c02400	COG0784	Response regulator, receiver
AZL_c02410	COG0747	negative chemotaxis
AZL_c02420	COG3852	Histidine kinase
AZL_c02430	COG5433	transposase activity
AZL_c02460	COG4176	ABC-type proline glycine betaine transport system permease component
AZL_c02470	COG4175	Glycine betaine
AZL_c02480	COG1595	DNA-templated transcription, initiation
AZL_c02490	COG3806	Anti-sigma factor
AZL_c02540	COG2132	Multicopper oxidase
AZL_c02580	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AZL_c02590	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AZL_c02600	COG0583	DNA-binding transcription factor activity
AZL_c02610	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AZL_c02610	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AZL_c02620	COG1105	Belongs to the carbohydrate kinase PfkB family
AZL_c02630	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AZL_c02630	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AZL_c02640	COG1609	Transcriptional regulator
AZL_c02660	COG0489	protein tyrosine kinase activity
AZL_c02660	COG3206	protein involved in exopolysaccharide biosynthesis
AZL_c02700	COG0438	transferase activity, transferring glycosyl groups
AZL_c02730	COG0438	transferase activity, transferring glycosyl groups
AZL_c02790	COG1131	(ABC) transporter
AZL_c02820	COG0366	Alpha amylase catalytic
AZL_c02850	COG0459	protein refolding
AZL_c02900	COG3474	cytochrome
AZL_c02970	COG4566	intracellular signal transduction
AZL_c03010	COG2814	Major facilitator Superfamily
AZL_c03020	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
AZL_c03060	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AZL_c03080	COG0583	DNA-binding transcription factor activity
AZL_c03090	COG1028	Short-chain dehydrogenase reductase Sdr
AZL_c03140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZL_c03170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AZL_c03180	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AZL_c03200	COG1012	belongs to the aldehyde dehydrogenase family
AZL_c03230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZL_c03250	COG0454	-acetyltransferase
AZL_c03280	COG0747	negative chemotaxis
AZL_c03290	COG0601	transmembrane transport
AZL_c03300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZL_c03310	COG4172	Belongs to the ABC transporter superfamily
AZL_c03320	COG1522	sequence-specific DNA binding
AZL_c03340	COG0583	DNA-binding transcription factor activity
AZL_c03350	COG1122	ATPase activity
AZL_c03360	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AZL_c03370	COG1268	BioY protein
AZL_c03380	COG0318	PFAM AMP-dependent synthetase and ligase
AZL_c03390	COG0183	Belongs to the thiolase family
AZL_c03440	COG0577	efflux transmembrane transporter activity
AZL_c03440	COG1136	(ABC) transporter
AZL_c03450	COG0577	efflux transmembrane transporter activity
AZL_c03450	COG1136	(ABC) transporter
AZL_c03470	COG1785	Belongs to the alkaline phosphatase family
AZL_c03490	COG1136	(ABC) transporter
AZL_c03500	COG1136	(ABC) transporter
AZL_c03500	COG0577	efflux transmembrane transporter activity
AZL_c03510	COG1609	Transcriptional regulator
AZL_c03550	COG5433	transposase activity
AZL_c03570	COG1472	Belongs to the glycosyl hydrolase 3 family
AZL_c03590	COG0745	RESPONSE REGULATOR receiver
AZL_c03600	COG5002	protein histidine kinase activity
AZL_c03600	COG5000	phosphorelay sensor kinase activity
AZL_c03610	COG1131	(ABC) transporter
AZL_c03620	COG0842	Transport permease protein
AZL_c03630	COG3293	Transposase
AZL_c03660	COG5002	protein histidine kinase activity
AZL_c03670	COG3119	arylsulfatase activity
AZL_c03690	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AZL_c03770	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AZL_c03880	COG3436	PFAM IS66 Orf2 family protein
AZL_c03890	COG4584	PFAM Integrase catalytic
AZL_c03900	COG1484	DNA-dependent DNA replication
AZL_c03930	COG3436	PFAM IS66 Orf2 family protein
AZL_c03940	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AZL_c03950	COG4372	Transposase
AZL_c03960	COG4372	Transposase
AZL_c03980	COG4372	Transposase
AZL_c04000	COG4372	Transposase
AZL_c04010	COG4372	Transposase
AZL_c04080	COG5433	transposase activity
AZL_c04090	COG0704	Plays a role in the regulation of phosphate uptake
AZL_c04100	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AZL_c04110	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AZL_c04120	COG1028	Short-chain dehydrogenase reductase Sdr
AZL_c04130	COG1959	2 iron, 2 sulfur cluster binding
AZL_c04140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZL_c04150	COG1475	DNA binding
AZL_c04270	COG0719	Fe-S assembly protein
AZL_c04280	COG0396	ATPase activity
AZL_c04290	COG0719	Fe-S assembly protein
AZL_c04300	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AZL_c04310	COG0822	iron-sulfur transferase activity
AZL_c04320	COG2151	metal-sulfur cluster biosynthetic enzyme
AZL_c04330	COG0316	Belongs to the HesB IscA family
AZL_c04350	COG1741	Belongs to the pirin family
AZL_c04360	COG2329	Antibiotic biosynthesis monooxygenase
AZL_c04380	COG1414	Transcriptional regulator
AZL_c04390	COG3734	2-keto-3-deoxy-galactonokinase
AZL_c04400	COG0800	Aldolase
AZL_c04420	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AZL_c04430	COG1737	Transcriptional regulator
AZL_c04430	COG0837	glucose binding
AZL_c04440	COG1882	Formate acetyltransferase
AZL_c04450	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AZL_c04480	COG0583	DNA-binding transcription factor activity
AZL_c04500	COG1609	Transcriptional regulator
AZL_c04510	COG0246	Mannitol dehydrogenase
AZL_c04520	COG0674	pyruvate-flavodoxin oxidoreductase activity
AZL_c04520	COG1013	pyruvate-flavodoxin oxidoreductase activity
AZL_c04520	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AZL_c04530	COG2271	Major facilitator Superfamily
AZL_c04540	COG0840	transmembrane signaling receptor activity
AZL_c04580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZL_c04610	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AZL_c04610	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AZL_c04670	COG5002	protein histidine kinase activity
AZL_c04680	COG0745	RESPONSE REGULATOR receiver
AZL_c04680	COG3706	GGDEF domain
AZL_c04690	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AZL_c04700	COG2080	2 iron, 2 sulfur cluster binding
AZL_c04750	COG5433	transposase activity
AZL_c04770	COG0439	Biotin carboxylase
AZL_c04780	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AZL_c04860	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AZL_c04870	COG0408	coproporphyrinogen oxidase activity
AZL_c04910	COG0435	Glutathione S-transferase
AZL_c04920	COG0655	NAD(P)H dehydrogenase (quinone) activity
AZL_c04930	COG0583	DNA-binding transcription factor activity
AZL_c04980	COG1028	Short-chain dehydrogenase reductase Sdr
AZL_c04990	COG0542	response to heat
AZL_c05040	COG0697	spore germination
AZL_c05090	COG1484	DNA-dependent DNA replication
AZL_c05100	COG4584	PFAM Integrase catalytic
AZL_c05150	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AZL_c05170	COG1215	transferase activity, transferring glycosyl groups
AZL_c05210	COG0745	RESPONSE REGULATOR receiver
AZL_c05220	COG3275	phosphorelay sensor kinase activity
AZL_c05230	COG2205	protein histidine kinase activity
AZL_c05280	COG0795	lipopolysaccharide-transporting ATPase activity
AZL_c05310	COG1104	cysteine desulfurase activity
AZL_d00030	COG1846	Transcriptional regulator
AZL_d00070	COG0318	PFAM AMP-dependent synthetase and ligase
AZL_d00070	COG0204	Acyl-transferase
AZL_d00080	COG2884	Cell division ATP-binding protein ftsE
AZL_d00110	COG2217	Heavy metal translocating P-type atpase
AZL_d00120	COG2610	gluconate transmembrane transporter activity
AZL_d00130	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AZL_d00140	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AZL_d00150	COG1028	Short-chain dehydrogenase reductase Sdr
AZL_d00190	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AZL_d00190	COG1672	PFAM Archaeal ATPase
AZL_d00200	COG0129	dihydroxy-acid dehydratase activity
AZL_d00220	COG1566	PFAM secretion protein HlyD family protein
AZL_d00240	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AZL_d00300	COG0564	pseudouridine synthase activity
AZL_d00320	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AZL_d00340	COG0842	Transport permease protein
AZL_d00350	COG1129	ABC transporter
AZL_d00350	COG0842	Transport permease protein
AZL_d00360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZL_d00370	COG1609	Transcriptional regulator
AZL_d00380	COG3265	gluconokinase activity
AZL_d00400	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AZL_d00410	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AZL_d00450	COG0840	transmembrane signaling receptor activity
AZL_d00460	COG3485	protocatechuate 3,4-dioxygenase
AZL_d00470	COG3485	protocatechuate 3,4-dioxygenase
AZL_d00490	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AZL_d00500	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AZL_d00510	COG0183	Belongs to the thiolase family
AZL_d00520	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AZL_d00530	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AZL_d00540	COG0683	leucine binding
AZL_d00590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZL_d00620	COG1126	abc transporter atp-binding protein
AZL_d00630	COG0765	amino acid transport
AZL_d00640	COG4597	amino acid ABC transporter
AZL_d00650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZL_d00680	COG0840	transmembrane signaling receptor activity
AZL_d00710	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AZL_d00720	COG0347	Belongs to the P(II) protein family
AZL_d00750	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AZL_d00760	COG1121	(ABC) transporter
AZL_d00780	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AZL_d00790	COG3437	response regulator, receiver
AZL_d00790	COG0784	Response regulator, receiver
AZL_d00800	COG1280	lysine exporter protein (LysE YggA)
AZL_d00830	COG1396	sequence-specific DNA binding
AZL_d00830	COG3800	Transcriptional regulator
AZL_d00840	COG2224	Isocitrate lyase
AZL_d00850	COG0693	protein deglycase activity
AZL_d00870	COG0287	Prephenate dehydrogenase
AZL_d00880	COG0583	DNA-binding transcription factor activity
AZL_d00890	COG0450	alkyl hydroperoxide reductase
AZL_d00920	COG0583	DNA-binding transcription factor activity
AZL_d00940	COG1028	Short-chain dehydrogenase reductase Sdr
AZL_d00990	COG2814	Major facilitator Superfamily
AZL_d01020	COG1045	serine acetyltransferase
AZL_d01040	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AZL_d01080	COG0306	phosphate transporter
AZL_d01090	COG2205	protein histidine kinase activity
AZL_d01090	COG2202	Pas domain
AZL_d01150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AZL_d01160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AZL_d01160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AZL_d01180	COG2084	Dehydrogenase
AZL_d01190	COG3622	Belongs to the hyi family
AZL_d01200	COG1902	pentaerythritol trinitrate reductase activity
AZL_d01200	COG0446	pyridine nucleotide-disulphide oxidoreductase
AZL_d01210	COG3550	peptidyl-serine autophosphorylation
AZL_d01230	COG1802	Transcriptional regulator
AZL_d01240	COG0861	Integral membrane protein TerC family
AZL_d01270	COG1309	transcriptional regulator
AZL_d01300	COG0493	'glutamate synthase
AZL_d01310	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AZL_d01320	COG1028	Short-chain dehydrogenase reductase Sdr
AZL_d01330	COG1309	transcriptional regulator
AZL_d01340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AZL_d01360	COG2721	sulfolactate sulfo-lyase activity
AZL_d01370	COG1904	glucuronate isomerase
AZL_d01380	COG1802	Transcriptional regulator
AZL_d01390	COG1942	4-Oxalocrotonate Tautomerase
AZL_d01410	COG0625	glutathione transferase activity
AZL_d01420	COG1733	regulation of RNA biosynthetic process
AZL_d01430	COG1917	Cupin 2, conserved barrel domain protein
AZL_d01440	COG1028	Short-chain dehydrogenase reductase Sdr
AZL_d01470	COG1802	Transcriptional regulator
AZL_d01490	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZL_d01500	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZL_d01510	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AZL_d01540	COG2050	protein possibly involved in aromatic compounds catabolism
AZL_d01550	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZL_d01560	COG1024	Enoyl-CoA hydratase
AZL_d01580	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AZL_d01590	COG2151	metal-sulfur cluster biosynthetic enzyme
AZL_d01600	COG3396	Phenylacetate-CoA oxygenase
AZL_d01610	COG3460	Phenylacetate-CoA oxygenase
AZL_d01620	COG3396	Phenylacetate-CoA oxygenase
AZL_d01630	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AZL_d01650	COG2198	Histidine kinase
AZL_d01650	COG2205	protein histidine kinase activity
AZL_d01650	COG0784	Response regulator, receiver
AZL_d01680	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AZL_d01720	COG0587	DNA-directed DNA polymerase activity
AZL_d01760	COG0405	Gamma-glutamyltransferase
AZL_d01840	COG3806	Anti-sigma factor
AZL_d01850	COG1595	DNA-templated transcription, initiation
AZL_d01880	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AZL_d01910	COG4221	oxidoreductase activity
AZL_d01930	COG0848	biopolymer transport protein
AZL_d01960	COG0671	phosphoesterase, PA-phosphatase related
AZL_d01970	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AZL_d01980	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AZL_d01990	COG0736	holo-[acyl-carrier-protein] synthase activity
AZL_d02000	COG0793	Belongs to the peptidase S41A family
AZL_d02080	COG1295	ribonuclease BN
AZL_d02120	COG2723	6-phospho-beta-galactosidase activity
AZL_d02140	COG2233	PERMEase
AZL_d02170	COG1280	lysine exporter protein (LysE YggA)
AZL_d02200	COG4303	Ethanolamine ammonia lyase large subunit
AZL_d02220	COG0531	amino acid
AZL_d02250	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AZL_d02300	COG1278	Cold shock
AZL_d02310	COG3012	SEC-C Motif Domain Protein
AZL_d02330	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AZL_d02410	COG0297	glycogen (starch) synthase activity
AZL_d02420	COG0501	Belongs to the peptidase M48B family
AZL_d02440	COG1522	sequence-specific DNA binding
AZL_d02450	COG3293	Transposase
AZL_d02480	COG0438	transferase activity, transferring glycosyl groups
AZL_d02510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AZL_d02530	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AZL_d02550	COG0489	protein tyrosine kinase activity
AZL_d02550	COG3206	protein involved in exopolysaccharide biosynthesis
AZL_d02570	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AZL_d02590	COG1131	(ABC) transporter
AZL_d02610	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AZL_d02620	COG0372	Belongs to the citrate synthase family
AZL_d02630	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AZL_d02640	COG1971	Probably functions as a manganese efflux pump
AZL_d02660	COG0402	S-adenosylhomocysteine deaminase activity
AZL_d02680	COG1309	transcriptional regulator
AZL_d02700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AZL_d02740	COG0784	Response regulator, receiver
AZL_d02760	COG3214	Protein conserved in bacteria
AZL_d02780	COG1522	sequence-specific DNA binding
AZL_d02810	COG0427	acetyl-CoA hydrolase
AZL_d02840	COG2202	Pas domain
AZL_d02840	COG2205	protein histidine kinase activity
AZL_d02870	COG1012	belongs to the aldehyde dehydrogenase family
AZL_d02890	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AZL_d02920	COG4948	Mandelate Racemase Muconate Lactonizing
AZL_d02930	COG0583	DNA-binding transcription factor activity
AZL_d02960	COG1157	protein secretion by the type III secretion system
AZL_d02970	COG0745	RESPONSE REGULATOR receiver
AZL_d02980	COG1278	Cold shock
AZL_d03030	COG2201	protein-glutamate methylesterase activity
AZL_d03040	COG0835	chemotaxis
AZL_d03050	COG0643	Histidine kinase
AZL_d03050	COG2198	Histidine kinase
AZL_d03090	COG3920	Histidine kinase
AZL_d03110	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AZL_d03120	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AZL_d03130	COG0583	DNA-binding transcription factor activity
AZL_d03330	COG2099	Precorrin-6x reductase
AZL_d03390	COG1797	cobyrinic acid a,c-diamide synthase activity
AZL_d03400	COG0778	Nitroreductase
AZL_d03410	COG0662	Cupin 2, conserved barrel domain protein
AZL_d03410	COG2207	Transcriptional regulator
AZL_d03420	COG1028	Short-chain dehydrogenase reductase Sdr
AZL_d03440	COG2198	Histidine kinase
AZL_d03440	COG0643	Histidine kinase
AZL_d03460	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AZL_d03480	COG2201	protein-glutamate methylesterase activity
AZL_d03490	COG0835	chemotaxis
AZL_d03500	COG0840	transmembrane signaling receptor activity
AZL_d03510	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AZL_d03510	COG1776	CheC inhibitor of MCP methylation
AZL_d03520	COG2201	protein-glutamate methylesterase activity
AZL_d03530	COG0457	Tetratricopeptide repeat
AZL_d03530	COG0859	PFAM glycosyl transferase family 9
AZL_d03540	COG1464	Belongs to the NlpA lipoprotein family
AZL_d03550	COG2011	ABC-type metal ion transport system permease component
AZL_d03560	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AZL_d03570	COG1464	Belongs to the NlpA lipoprotein family
AZL_d03600	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AZL_d03620	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AZL_d03690	COG1530	ribonuclease E activity
AZL_d03700	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AZL_d03760	COG0745	RESPONSE REGULATOR receiver
AZL_d03860	COG1609	Transcriptional regulator
AZL_d03880	COG2814	Major facilitator Superfamily
AZL_d03900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZL_d03910	COG3842	ATPase activity
AZL_d03930	COG1176	ABC-type spermidine putrescine transport system, permease component I
AZL_d04000	COG0840	transmembrane signaling receptor activity
AZL_d04020	COG0318	PFAM AMP-dependent synthetase and ligase
AZL_d04030	COG3655	Transcriptional regulator
AZL_d04060	COG1522	sequence-specific DNA binding
AZL_d04070	COG0686	Belongs to the AlaDH PNT family
AZL_d04100	COG0411	ABC transporter
AZL_d04130	COG0840	transmembrane signaling receptor activity
AZL_d04140	COG0745	RESPONSE REGULATOR receiver
AZL_d04150	COG0784	Response regulator, receiver
AZL_d04150	COG2198	Histidine kinase
AZL_d04150	COG2205	protein histidine kinase activity
AZL_d04280	COG0583	DNA-binding transcription factor activity
AZL_d04310	COG1051	belongs to the nudix hydrolase family
AZL_d04310	COG1056	cytidyltransferase-related domain
AZL_d04330	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AZL_d04350	COG0754	glutathionylspermidine amidase activity
AZL_d04360	COG5463	Belongs to the UPF0441 family
AZL_d04400	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AZL_d04400	COG1213	nucleotidyl transferase
AZL_d04420	COG4589	Belongs to the CDS family
AZL_d04450	COG4774	siderophore transport
AZL_d04470	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AZL_d04480	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AZL_d04530	COG2972	Histidine kinase
AZL_d04530	COG0840	transmembrane signaling receptor activity
AZL_d04540	COG1028	Short-chain dehydrogenase reductase Sdr
AZL_d04590	COG0564	pseudouridine synthase activity
AZL_d04600	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AZL_d04610	COG0454	-acetyltransferase
AZL_d04670	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AZL_d04680	COG5433	transposase activity
AZL_d04700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZL_d04730	COG0667	Aldo Keto reductase
AZL_d04740	COG0306	phosphate transporter
AZL_d04750	COG1902	pentaerythritol trinitrate reductase activity
AZL_d04770	COG1192	Involved in chromosome partitioning
AZL_d04800	COG1960	acyl-CoA dehydrogenase activity
AZL_d04870	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AZL_d04890	COG4133	protoheme IX ABC transporter activity
AZL_d04920	COG0601	transmembrane transport
AZL_d04930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZL_d04960	COG0438	transferase activity, transferring glycosyl groups
AZL_d04970	COG0588	phosphoglycerate mutase activity
AZL_d05020	COG0583	DNA-binding transcription factor activity
AZL_d05040	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AZL_d05050	COG1126	abc transporter atp-binding protein
AZL_d05080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZL_d05090	COG1737	Transcriptional regulator
AZL_d05150	COG0667	Aldo Keto reductase
AZL_d05160	COG2814	Major facilitator Superfamily
AZL_e00040	COG1686	Belongs to the peptidase S11 family
AZL_e00060	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AZL_e00070	COG2814	Major facilitator Superfamily
AZL_e00100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZL_e00110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AZL_e00120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZL_e00320	COG4584	PFAM Integrase catalytic
AZL_e00330	COG1484	DNA-dependent DNA replication
AZL_e00360	COG3328	transposase activity
AZL_e00390	COG2433	Pfam Transposase IS66
AZL_e00440	COG3459	Glycosyltransferase 36 associated
AZL_e00460	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AZL_e00570	COG2197	response regulator
AZL_e00610	COG4372	Transposase
AZL_e00620	COG3436	PFAM IS66 Orf2 family protein
AZL_e00650	COG2197	response regulator
AZL_e00680	COG3436	PFAM IS66 Orf2 family protein
AZL_e00690	COG1982	Orn Lys Arg decarboxylase major
AZL_e00750	COG1706	bacterial-type flagellum-dependent cell motility
AZL_e00770	COG1256	bacterial-type flagellum assembly
AZL_e00780	COG1749	Flagellar hook protein flgE
AZL_e00800	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AZL_e00820	COG4786	Flagellar basal body rod
AZL_e00830	COG4786	Flagellar basal body rod
AZL_e00840	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
AZL_e00850	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AZL_e00870	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AZL_e00930	COG1766	The M ring may be actively involved in energy transduction
AZL_e00950	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AZL_e00960	COG1338	Plays a role in the flagellum-specific transport system
AZL_e00980	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AZL_e01010	COG0745	RESPONSE REGULATOR receiver
AZL_e01040	COG5443	negative regulation of bacterial-type flagellum assembly
AZL_e01070	COG0697	spore germination
AZL_e01100	COG1157	protein secretion by the type III secretion system
AZL_e01120	COG1558	bacterial-type flagellum-dependent cell motility
AZL_e01130	COG1677	Flagellar hook-basal body complex protein FliE
AZL_e01160	COG1120	ATPase activity
AZL_e01170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AZL_e01180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AZL_e01190	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AZL_e01210	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AZL_e01230	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AZL_e01240	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AZL_e01250	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AZL_e01270	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AZL_e01300	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AZL_e01310	COG1845	cytochrome c oxidase, subunit III
AZL_e01320	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AZL_e01330	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AZL_e01340	COG0477	Major facilitator Superfamily
AZL_e01370	COG1988	membrane-bound metal-dependent
AZL_e01390	COG2814	Major facilitator Superfamily
AZL_e01420	COG4178	(ABC) transporter
AZL_e01440	COG0840	transmembrane signaling receptor activity
AZL_e01450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AZL_e01470	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AZL_e01560	COG4993	Dehydrogenase
AZL_e01580	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZL_e01600	COG2086	electron transfer activity
AZL_e01630	COG2723	6-phospho-beta-galactosidase activity
AZL_e01660	COG0840	transmembrane signaling receptor activity
AZL_e01700	COG1127	ABC transporter
AZL_e01710	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AZL_e01720	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AZL_e01730	COG0305	Participates in initiation and elongation during chromosome replication
AZL_e01760	COG2010	Cytochrome c
AZL_e01780	COG0598	Magnesium transport protein CorA
AZL_e01840	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AZL_e01860	COG3415	Transposase
AZL_e01870	COG3335	DDE superfamily endonuclease
AZL_e01930	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AZL_e01940	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AZL_e01960	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AZL_e01960	COG3218	ABC-type transport auxiliary lipoprotein component
AZL_e02000	COG2202	Pas domain
AZL_e02000	COG2205	protein histidine kinase activity
AZL_e02020	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AZL_e02050	COG2703	oxygen carrier activity
AZL_e02120	COG0521	Mo-molybdopterin cofactor biosynthetic process
AZL_e02130	COG0741	lytic transglycosylase activity
AZL_e02140	COG1573	uracil-dna glycosylase
AZL_e02170	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AZL_e02190	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AZL_e02200	COG1063	alcohol dehydrogenase
AZL_e02210	COG0246	Mannitol dehydrogenase
AZL_e02220	COG1802	Transcriptional regulator
AZL_e02230	COG1176	ABC-type spermidine putrescine transport system, permease component I
AZL_e02250	COG3842	ATPase activity
AZL_e02270	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AZL_e02300	COG3416	Protein conserved in bacteria
AZL_e02320	COG3920	Histidine kinase
AZL_e02340	COG5265	(ABC) transporter
AZL_e02350	COG1032	radical SAM domain protein
AZL_e02380	COG1396	sequence-specific DNA binding
AZL_e02400	COG2271	Major facilitator Superfamily
AZL_e02410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZL_e02420	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AZL_e02440	COG0573	inorganic phosphate transmembrane transporter activity
AZL_e02450	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AZL_e02470	COG0625	glutathione transferase activity
AZL_e02480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZL_e02530	COG2814	Major facilitator Superfamily
AZL_e02560	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AZL_e02590	COG5002	protein histidine kinase activity
AZL_e02590	COG3850	Histidine kinase
AZL_e02600	COG0745	RESPONSE REGULATOR receiver
AZL_e02620	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AZL_e02650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZL_e02680	COG2885	chlorophyll binding
AZL_e02680	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AZL_e02740	COG0411	ABC transporter
AZL_e02790	COG1940	carbohydrate kinase activity
AZL_e02830	COG0463	Glycosyl transferase, family 2
AZL_e02880	COG0583	DNA-binding transcription factor activity
AZL_e02890	COG4191	Histidine kinase
AZL_e02890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZL_e02900	COG1238	metal cluster binding
AZL_e02960	COG4191	Histidine kinase
AZL_e02980	COG0840	transmembrane signaling receptor activity
AZL_e03010	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AZL_e03060	COG3842	ATPase activity
AZL_e03070	COG3842	ATPase activity
AZL_e03100	COG1349	DNA-binding transcription factor activity
AZL_e03180	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AZL_e03190	COG0697	spore germination
AZL_e03320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZL_e03330	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZL_e03340	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZL_e03360	COG2186	Transcriptional regulator
AZL_e03370	COG1312	Catalyzes the dehydration of D-mannonate
AZL_e03380	COG1028	Short-chain dehydrogenase reductase Sdr
AZL_e03390	COG2271	Major facilitator Superfamily
AZL_e03470	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AZL_e03470	COG1648	precorrin-2 dehydrogenase activity
AZL_e03480	COG0243	molybdopterin cofactor binding
AZL_e03500	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AZL_e03510	COG1116	anion transmembrane transporter activity
AZL_e03510	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZL_e03530	COG1116	anion transmembrane transporter activity
AZL_e03540	COG0656	L-ascorbic acid biosynthetic process
AZL_e03550	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AZL_e03570	COG1172	Belongs to the binding-protein-dependent transport system permease family
AZL_e03580	COG1172	Belongs to the binding-protein-dependent transport system permease family
AZL_e03590	COG1129	ABC transporter
AZL_e03600	COG1879	ABC-type sugar transport system periplasmic component
AZL_e03670	COG1129	ABC transporter
AZL_e03680	COG4214	carbohydrate transport
AZL_e03700	COG0129	dihydroxy-acid dehydratase activity
AZL_e03720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZL_e03740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZL_e03740	COG2205	protein histidine kinase activity
AZL_e03750	COG0528	UMP kinase activity
AZL_e03760	COG0528	UMP kinase activity
AZL_e03790	COG0372	Belongs to the citrate synthase family
AZL_e03810	COG2204	response regulator
AZL_e03820	COG2186	Transcriptional regulator
AZL_e03830	COG1620	l-lactate permease
AZL_e03850	COG0247	lactate metabolic process
AZL_e03860	COG1139	Iron-sulfur cluster binding protein
AZL_e03880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZL_e03890	COG3283	Transcriptional regulator of aromatic amino acids metabolism
AZL_e03910	COG3284	Transcriptional regulator
AZL_e03930	COG2205	protein histidine kinase activity
AZL_e03940	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AZL_e03970	COG3604	Transcriptional regulator
AZL_e04000	COG0179	Fumarylacetoacetate (FAA) hydrolase
AZL_e04010	COG1737	Transcriptional regulator
AZL_e04040	COG1966	Carbon starvation protein
AZL_e04050	COG3279	Response regulator of the LytR AlgR family
AZL_e04060	COG3275	phosphorelay sensor kinase activity
AZL_e04090	COG0318	PFAM AMP-dependent synthetase and ligase
AZL_e04110	COG0644	oxidoreductase
AZL_e04120	COG0583	DNA-binding transcription factor activity
AZL_e04140	COG1475	DNA binding
AZL_e04150	COG1192	Involved in chromosome partitioning
AZL_f00030	COG1132	(ABC) transporter
AZL_f00040	COG0438	transferase activity, transferring glycosyl groups
AZL_f00050	COG1086	Polysaccharide biosynthesis protein
AZL_f00060	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AZL_f00140	COG5433	transposase activity
AZL_f00160	COG4106	trans-aconitate 2-methyltransferase activity
AZL_f00270	COG4638	Rieske (2fe-2S)
AZL_f00340	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AZL_f00390	COG2801	Transposase and inactivated derivatives
AZL_f00430	COG0656	L-ascorbic acid biosynthetic process
AZL_f00440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AZL_f00450	COG3958	Transketolase
AZL_f00460	COG3959	Transketolase, thiamine diphosphate binding domain
AZL_f00490	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AZL_f00550	COG4584	PFAM Integrase catalytic
AZL_f00560	COG1484	DNA-dependent DNA replication
AZL_f00570	COG3547	Transposase (IS116 IS110 IS902 family)
AZL_f00610	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AZL_f00670	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AZL_f00690	COG1487	ribonuclease activity
AZL_f00700	COG2124	cytochrome p450
AZL_f00770	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AZL_f00790	COG3251	PFAM MbtH domain protein
AZL_f00810	COG3328	transposase activity
AZL_f00820	COG3335	DDE superfamily endonuclease
AZL_f00830	COG3415	Transposase
AZL_f00840	COG3328	transposase activity
AZL_f00900	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AZL_f00950	COG4584	PFAM Integrase catalytic
AZL_f00960	COG1484	DNA-dependent DNA replication
AZL_f01060	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AZL_f01100	COG0438	transferase activity, transferring glycosyl groups
AZL_f01110	COG0463	Glycosyl transferase, family 2
AZL_f01160	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AZL_f01180	COG5433	transposase activity
AZL_f01210	COG0175	sulfate reduction
AZL_f01260	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AZL_f01270	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AZL_f01350	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AZL_f01360	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AZL_f01390	COG1091	dTDP-4-dehydrorhamnose reductase activity
AZL_f01440	COG3436	PFAM IS66 Orf2 family protein
AZL_f01450	COG1484	DNA-dependent DNA replication
AZL_f01460	COG4584	PFAM Integrase catalytic
AZL_f01470	COG4372	Transposase
AZL_f01480	COG4372	Transposase
AZL_f01500	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AZL_f01560	COG0457	Tetratricopeptide repeat
AZL_f01560	COG0859	PFAM glycosyl transferase family 9
AZL_f01590	COG2274	protein secretion by the type I secretion system
AZL_f01640	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AZL_f01670	COG0297	glycogen (starch) synthase activity
AZL_f01750	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AZL_f01780	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AZL_f01800	COG1091	dTDP-4-dehydrorhamnose reductase activity
AZL_f01820	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AZL_f01840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZL_f01850	COG2274	protein secretion by the type I secretion system
AZL_f01870	COG0662	Cupin 2, conserved barrel domain protein
AZL_f01870	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family