locus-tag	class	description
DEW08_00010	COG0713	ATP synthesis coupled electron transport
DEW08_00025	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DEW08_00030	COG1034	ATP synthesis coupled electron transport
DEW08_00040	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
DEW08_00045	COG0649	NAD binding
DEW08_00050	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEW08_00055	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEW08_00060	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEW08_00095	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DEW08_00115	COG0741	lytic transglycosylase activity
DEW08_00130	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DEW08_00140	COG1360	Flagellar Motor Protein
DEW08_00145	COG2308	Evidence 4 Homologs of previously reported genes of
DEW08_00155	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
DEW08_00170	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
DEW08_00175	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DEW08_00180	COG1381	Involved in DNA repair and RecF pathway recombination
DEW08_00185	COG5001	Diguanylate cyclase
DEW08_00205	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DEW08_00210	COG1684	flagellar biosynthetic protein fliR
DEW08_00215	COG1987	bacterial-type flagellum assembly
DEW08_00220	COG1677	Flagellar hook-basal body complex protein FliE
DEW08_00225	COG1558	bacterial-type flagellum-dependent cell motility
DEW08_00230	COG1815	bacterial-type flagellum-dependent cell motility
DEW08_00240	COG2257	FlhB HrpN YscU SpaS Family
DEW08_00255	COG1338	Plays a role in the flagellum-specific transport system
DEW08_00315	COG0745	RESPONSE REGULATOR receiver
DEW08_00330	COG2814	Major facilitator Superfamily
DEW08_00335	COG0583	DNA-binding transcription factor activity
DEW08_00345	COG1024	Enoyl-CoA hydratase
DEW08_00355	COG0410	ABC transporter
DEW08_00360	COG0411	ABC transporter
DEW08_00370	COG0559	Belongs to the binding-protein-dependent transport system permease family
DEW08_00380	COG0318	PFAM AMP-dependent synthetase and ligase
DEW08_00390	COG0625	glutathione transferase activity
DEW08_00465	COG2099	Precorrin-6x reductase
DEW08_00500	COG0778	Nitroreductase
DEW08_00515	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DEW08_00515	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DEW08_00530	COG3550	peptidyl-serine autophosphorylation
DEW08_00535	COG0191	fructose-bisphosphate aldolase activity
DEW08_00540	COG0318	PFAM AMP-dependent synthetase and ligase
DEW08_00545	COG1404	Belongs to the peptidase S8 family
DEW08_00550	COG1132	(ABC) transporter
DEW08_00585	COG0733	neurotransmitter:sodium symporter activity
DEW08_00615	COG1028	Short-chain dehydrogenase reductase Sdr
DEW08_00630	COG0243	molybdopterin cofactor binding
DEW08_00630	COG3383	formate dehydrogenase (NAD+) activity
DEW08_00635	COG0437	4 iron, 4 sulfur cluster binding
DEW08_00640	COG2864	formate dehydrogenase
DEW08_00680	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DEW08_00690	COG0791	NLP P60 protein
DEW08_00695	COG1648	precorrin-2 dehydrogenase activity
DEW08_00695	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DEW08_00700	COG0243	molybdopterin cofactor binding
DEW08_00705	COG2146	nitrite reductase [NAD(P)H] activity
DEW08_00710	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DEW08_00720	COG1475	DNA binding
DEW08_00725	COG1192	Involved in chromosome partitioning
DEW08_00775	COG1278	Cold shock
DEW08_00805	COG1940	carbohydrate kinase activity
DEW08_00815	COG1175	transmembrane transport
DEW08_00925	COG5002	protein histidine kinase activity
DEW08_00925	COG2205	protein histidine kinase activity
DEW08_00925	COG0784	Response regulator, receiver
DEW08_00930	COG1609	Transcriptional regulator
DEW08_00935	COG0477	Major facilitator Superfamily
DEW08_00950	COG2084	Dehydrogenase
DEW08_00990	COG4221	oxidoreductase activity
DEW08_01000	COG0655	NAD(P)H dehydrogenase (quinone) activity
DEW08_01010	COG0583	DNA-binding transcription factor activity
DEW08_01020	COG1741	Belongs to the pirin family
DEW08_01025	COG0583	DNA-binding transcription factor activity
DEW08_01035	COG1028	Short-chain dehydrogenase reductase Sdr
DEW08_01075	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DEW08_01090	COG1271	oxidase subunit
DEW08_01095	COG1294	oxidase, subunit
DEW08_01105	COG4988	ABC transporter
DEW08_01110	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DEW08_01115	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DEW08_01120	COG1595	DNA-templated transcription, initiation
DEW08_01155	COG1082	Xylose isomerase domain protein TIM barrel
DEW08_01160	COG0840	transmembrane signaling receptor activity
DEW08_01170	COG1175	transmembrane transport
DEW08_01175	COG1653	transport
DEW08_01180	COG3842	ATPase activity
DEW08_01190	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DEW08_01195	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DEW08_01200	COG0583	DNA-binding transcription factor activity
DEW08_01220	COG3842	ATPase activity
DEW08_01225	COG1840	ABC-type Fe3 transport system, periplasmic component
DEW08_01235	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DEW08_01245	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
DEW08_01270	COG3842	ATPase activity
DEW08_01280	COG1840	ABC-type Fe3 transport system, periplasmic component
DEW08_01305	COG0446	pyridine nucleotide-disulphide oxidoreductase
DEW08_01310	COG3852	Histidine kinase
DEW08_01315	COG2204	response regulator
DEW08_01415	COG3179	chitinase
DEW08_01535	COG4626	Terminase
DEW08_01535	COG1802	Transcriptional regulator
DEW08_01590	COG1061	Type III restriction enzyme res subunit
DEW08_01630	COG1525	nuclease
DEW08_01650	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DEW08_01700	COG1131	(ABC) transporter
DEW08_01725	COG1032	radical SAM domain protein
DEW08_01730	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DEW08_01740	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DEW08_01760	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DEW08_01810	COG0303	'Molybdopterin
DEW08_01815	COG0315	cyclic pyranopterin monophosphate synthase activity
DEW08_01865	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DEW08_01870	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DEW08_01895	COG3344	reverse transcriptase
DEW08_01910	COG2877	3-deoxy-8-phosphooctulonate synthase activity
DEW08_01930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DEW08_01940	COG0678	peroxiredoxin activity
DEW08_01950	COG0148	phosphopyruvate hydratase activity
DEW08_01955	COG0596	Alpha beta hydrolase
DEW08_01970	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DEW08_01975	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DEW08_01990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DEW08_01995	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DEW08_02025	COG0708	Exodeoxyribonuclease III
DEW08_02030	COG0316	Belongs to the HesB IscA family
DEW08_02035	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DEW08_02050	COG1472	Belongs to the glycosyl hydrolase 3 family
DEW08_02055	COG1994	Peptidase M50
DEW08_02060	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DEW08_02065	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DEW08_02070	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DEW08_02075	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DEW08_02080	COG0805	protein transport
DEW08_02095	COG1283	sodium-dependent phosphate transmembrane transporter activity
DEW08_02100	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DEW08_02110	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DEW08_02130	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DEW08_02140	COG3737	Protein of unknown function (DUF498/DUF598)
DEW08_02150	COG3344	reverse transcriptase
DEW08_02160	COG1233	COG1233 Phytoene dehydrogenase and related
DEW08_02165	COG1562	ergosterol biosynthetic process
DEW08_02185	COG0840	transmembrane signaling receptor activity
DEW08_02190	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DEW08_02205	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DEW08_02210	COG0629	single-stranded DNA binding
DEW08_02245	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DEW08_02285	COG4581	dead DEAH box helicase
DEW08_02290	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DEW08_02330	COG2814	Major facilitator Superfamily
DEW08_02355	COG0427	acetyl-CoA hydrolase
DEW08_02365	COG0505	Belongs to the CarA family
DEW08_02370	COG1132	(ABC) transporter
DEW08_02385	COG0438	transferase activity, transferring glycosyl groups
DEW08_02410	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DEW08_02415	COG1596	polysaccharide export
DEW08_02435	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DEW08_02450	COG2050	protein possibly involved in aromatic compounds catabolism
DEW08_02455	COG1250	3-hydroxyacyl-CoA dehydrogenase
DEW08_02460	COG1024	Enoyl-CoA hydratase
DEW08_02465	COG1012	belongs to the aldehyde dehydrogenase family
DEW08_02470	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DEW08_02475	COG2151	metal-sulfur cluster biosynthetic enzyme
DEW08_02480	COG3396	Phenylacetate-CoA oxygenase
DEW08_02485	COG3460	Phenylacetate-CoA oxygenase
DEW08_02490	COG3396	Phenylacetate-CoA oxygenase
DEW08_02495	COG5002	protein histidine kinase activity
DEW08_02505	COG1764	response to oxidative stress
DEW08_02510	COG3707	response regulator
DEW08_02515	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DEW08_02515	COG1116	anion transmembrane transporter activity
DEW08_02520	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DEW08_02525	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DEW08_02530	COG1116	anion transmembrane transporter activity
DEW08_02540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DEW08_02555	COG0840	transmembrane signaling receptor activity
DEW08_02595	COG0745	RESPONSE REGULATOR receiver
DEW08_02600	COG2198	Histidine kinase
DEW08_02600	COG0784	Response regulator, receiver
DEW08_02600	COG2205	protein histidine kinase activity
DEW08_02610	COG5002	protein histidine kinase activity
DEW08_02655	COG0318	PFAM AMP-dependent synthetase and ligase
DEW08_02660	COG2186	Transcriptional regulator
DEW08_02665	COG1960	acyl-CoA dehydrogenase activity
DEW08_02685	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DEW08_02700	COG0559	Belongs to the binding-protein-dependent transport system permease family
DEW08_02720	COG0318	PFAM AMP-dependent synthetase and ligase
DEW08_02725	COG1012	belongs to the aldehyde dehydrogenase family
DEW08_02730	COG1960	acyl-CoA dehydrogenase activity
DEW08_02735	COG0183	Belongs to the thiolase family
DEW08_02740	COG1960	acyl-CoA dehydrogenase activity
DEW08_02745	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DEW08_02750	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DEW08_02770	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DEW08_02815	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DEW08_02815	COG1672	PFAM Archaeal ATPase
DEW08_02830	COG1846	Transcriptional regulator
DEW08_02840	COG2814	Major facilitator Superfamily
DEW08_02850	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DEW08_02885	COG0564	pseudouridine synthase activity
DEW08_02895	COG0484	heat shock protein binding
DEW08_02905	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DEW08_02920	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DEW08_02965	COG1346	cytolysis
DEW08_02970	COG1380	Effector of murein hydrolase LrgA
DEW08_02975	COG0583	DNA-binding transcription factor activity
DEW08_02980	COG0352	thiamine-phosphate diphosphorylase activity
DEW08_02980	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DEW08_02990	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DEW08_03015	COG4214	carbohydrate transport
DEW08_03020	COG1129	ABC transporter
DEW08_03030	COG4154	Belongs to the RbsD FucU family
DEW08_03045	COG3791	Glutathione-dependent formaldehyde-activating
DEW08_03050	COG2080	2 iron, 2 sulfur cluster binding
DEW08_03055	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
DEW08_03060	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DEW08_03070	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DEW08_03075	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DEW08_03085	COG3256	nitric oxide reductase
DEW08_03090	COG0714	Associated with various cellular activities
DEW08_03100	COG1845	cytochrome c oxidase, subunit III
DEW08_03115	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DEW08_03140	COG0546	phosphoglycolate phosphatase activity
DEW08_03195	COG5487	UPF0391 membrane protein
DEW08_03220	COG0655	NAD(P)H dehydrogenase (quinone) activity
DEW08_03235	COG4993	Dehydrogenase
DEW08_03240	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DEW08_03255	COG1176	ABC-type spermidine putrescine transport system, permease component I
DEW08_03260	COG3842	ATPase activity
DEW08_03275	COG2197	response regulator
DEW08_03280	COG3546	catalase activity
DEW08_03285	COG1758	RNA polymerase activity
DEW08_03305	COG3300	MHYT domain
DEW08_03305	COG5001	Diguanylate cyclase
DEW08_03325	COG1752	Esterase of the alpha-beta hydrolase superfamily
DEW08_03335	COG1324	tolerance protein
DEW08_03350	COG1403	HNH endonuclease
DEW08_03370	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DEW08_03405	COG3328	transposase activity
DEW08_03410	COG1203	CRISPR-associated helicase, Cas3
DEW08_03440	COG1518	maintenance of DNA repeat elements
DEW08_03455	COG3436	PFAM IS66 Orf2 family protein
DEW08_03565	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DEW08_03570	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DEW08_03575	COG2031	fatty acid transporter
DEW08_03580	COG0183	Belongs to the thiolase family
DEW08_03585	COG0840	transmembrane signaling receptor activity
DEW08_03595	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DEW08_03600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DEW08_03605	COG1309	transcriptional regulator
DEW08_03610	COG2273	Hydrolase Family 16
DEW08_03610	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
DEW08_03615	COG1272	protein, Hemolysin III
DEW08_03635	COG0861	Integral membrane protein TerC family
DEW08_03670	COG4771	TonB-dependent receptor
DEW08_03675	COG3720	iron ion transport
DEW08_03680	COG4558	Periplasmic binding protein
DEW08_03685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEW08_03690	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DEW08_03700	COG3842	ATPase activity
DEW08_03705	COG1176	ABC-type spermidine putrescine transport system, permease component I
DEW08_03710	COG1177	transmembrane transport
DEW08_03715	COG2957	Belongs to the agmatine deiminase family
DEW08_03720	COG0840	transmembrane signaling receptor activity
DEW08_03735	COG3328	transposase activity
DEW08_03805	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DEW08_03865	COG0714	Associated with various cellular activities
DEW08_03885	COG2249	NAD(P)H dehydrogenase (quinone) activity
DEW08_03895	COG0408	coproporphyrinogen oxidase activity
DEW08_03900	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DEW08_03915	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DEW08_03915	COG2857	Cytochrome c1
DEW08_03935	COG0640	Transcriptional regulator
DEW08_03945	COG0123	including yeast histone deacetylase and acetoin utilization protein
DEW08_03955	COG0142	geranyltranstransferase activity
DEW08_03960	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DEW08_03965	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DEW08_03985	COG0784	Response regulator, receiver
DEW08_03985	COG5002	protein histidine kinase activity
DEW08_03985	COG2205	protein histidine kinase activity
DEW08_03990	COG3437	response regulator, receiver
DEW08_03995	COG5001	Diguanylate cyclase
DEW08_03995	COG3300	MHYT domain
DEW08_04005	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DEW08_04010	COG0483	inositol monophosphate 1-phosphatase activity
DEW08_04030	COG0583	DNA-binding transcription factor activity
DEW08_04040	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DEW08_04045	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DEW08_04050	COG0509	glycine decarboxylation via glycine cleavage system
DEW08_04065	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DEW08_04070	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DEW08_04075	COG0328	RNA-DNA hybrid ribonuclease activity
DEW08_04080	COG3585	molybdate ion transport
DEW08_04100	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
DEW08_04120	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DEW08_04130	COG0739	heme binding
DEW08_04130	COG0741	lytic transglycosylase activity
DEW08_04130	COG1196	nuclear chromosome segregation
DEW08_04160	COG2863	cytochrome
DEW08_04180	COG4608	Belongs to the ABC transporter superfamily
DEW08_04190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEW08_04195	COG0601	transmembrane transport
DEW08_04200	COG0747	negative chemotaxis
DEW08_04210	COG3394	polysaccharide catabolic process
DEW08_04225	COG0784	Response regulator, receiver
DEW08_04230	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DEW08_04235	COG3920	Histidine kinase
DEW08_04245	COG0625	glutathione transferase activity
DEW08_04295	COG0457	Tetratricopeptide repeat
DEW08_04295	COG0859	PFAM glycosyl transferase family 9
DEW08_04305	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DEW08_04310	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DEW08_04315	COG1028	Short-chain dehydrogenase reductase Sdr
DEW08_04340	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
DEW08_04345	COG2089	acid synthase
DEW08_04370	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DEW08_04385	COG0280	phosphate acetyltransferase
DEW08_04385	COG0281	malic enzyme
DEW08_04390	COG1301	dicarboxylic acid transport
DEW08_04395	COG4191	Histidine kinase
DEW08_04400	COG2204	response regulator
DEW08_04405	COG0678	peroxiredoxin activity
DEW08_04415	COG1678	Uncharacterized ACR, COG1678
DEW08_04420	COG0314	molybdopterin synthase activity
DEW08_04425	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DEW08_04430	COG0303	'Molybdopterin
DEW08_04435	COG0546	phosphoglycolate phosphatase activity
DEW08_04440	COG1763	Mo-molybdopterin cofactor biosynthetic process
DEW08_04445	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DEW08_04455	COG1028	Short-chain dehydrogenase reductase Sdr
DEW08_04475	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DEW08_04480	COG0037	tRNA processing
DEW08_04505	COG0848	biopolymer transport protein
DEW08_04515	COG0824	Thioesterase
DEW08_04520	COG2255	four-way junction helicase activity
DEW08_04525	COG0632	four-way junction helicase activity
DEW08_04535	COG0217	transcriptional regulatory protein
DEW08_04545	COG1692	metallophosphoesterase
DEW08_04550	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DEW08_04580	COG0840	transmembrane signaling receptor activity
DEW08_04600	COG1830	Aldolase
DEW08_04605	COG0352	thiamine-phosphate diphosphorylase activity
DEW08_04625	COG0737	Belongs to the 5'-nucleotidase family
DEW08_04650	COG1132	(ABC) transporter
DEW08_04770	COG0306	phosphate transporter
DEW08_04780	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DEW08_04800	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DEW08_04805	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DEW08_04810	COG0318	PFAM AMP-dependent synthetase and ligase
DEW08_04825	COG0840	transmembrane signaling receptor activity
DEW08_04840	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DEW08_04845	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DEW08_04860	COG0776	regulation of translation
DEW08_04875	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DEW08_04880	COG0840	transmembrane signaling receptor activity
DEW08_04905	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DEW08_04910	COG0612	Peptidase, M16
DEW08_04940	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
DEW08_04945	COG0109	protoheme IX farnesyltransferase activity
DEW08_04950	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DEW08_04955	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DEW08_04965	COG0312	modulator of DNA gyrase
DEW08_04980	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DEW08_04990	COG5487	UPF0391 membrane protein
DEW08_05000	COG0741	lytic transglycosylase activity
DEW08_05000	COG1196	nuclear chromosome segregation
DEW08_05000	COG0739	heme binding
DEW08_05005	COG2267	carboxylic ester hydrolase activity
DEW08_05020	COG2226	methyltransferase
DEW08_05035	COG0729	surface antigen
DEW08_05050	COG1840	ABC-type Fe3 transport system, periplasmic component
DEW08_05055	COG3842	ATPase activity
DEW08_05080	COG1764	response to oxidative stress
DEW08_05085	COG1846	Transcriptional regulator
DEW08_05105	COG0754	glutathionylspermidine amidase activity
DEW08_05110	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DEW08_05130	COG3546	catalase activity
DEW08_05135	COG2223	nitrite transmembrane transporter activity
DEW08_05140	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
DEW08_05150	COG2770	Histidine kinase
DEW08_05150	COG3437	response regulator, receiver
DEW08_05155	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DEW08_05160	COG1234	tRNA 3'-trailer cleavage
DEW08_05175	COG0259	pyridoxamine-phosphate oxidase activity
DEW08_05190	COG1295	ribonuclease BN
DEW08_05195	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DEW08_05205	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DEW08_05220	COG0616	signal peptide processing
DEW08_05230	COG2205	protein histidine kinase activity
DEW08_05235	COG0390	transport system, permease component
DEW08_05240	COG1116	anion transmembrane transporter activity
DEW08_05250	COG0628	permease
DEW08_05260	COG0392	lysyltransferase activity
DEW08_05265	COG0583	DNA-binding transcription factor activity
DEW08_05270	COG0375	protein maturation
DEW08_05275	COG3383	formate dehydrogenase (NAD+) activity
DEW08_05280	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
DEW08_05285	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
DEW08_05295	COG0650	Formate hydrogenlyase subunit 4
DEW08_05300	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DEW08_05310	COG0651	ATP synthesis coupled electron transport
DEW08_05315	COG3261	NADH dehydrogenase
DEW08_05315	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
DEW08_05325	COG3260	NADH ubiquinone oxidoreductase 20
DEW08_05335	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
DEW08_05340	COG2116	formate transmembrane transporter activity
DEW08_05345	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DEW08_05355	COG0375	protein maturation
DEW08_05395	COG1522	sequence-specific DNA binding
DEW08_05400	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DEW08_05410	COG2354	Protein conserved in bacteria
DEW08_05420	COG0784	Response regulator, receiver
DEW08_05420	COG3437	response regulator, receiver
DEW08_05435	COG1983	PspC domain protein
DEW08_05445	COG1842	Phage shock protein A
DEW08_05450	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DEW08_05460	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DEW08_05475	COG0492	ferredoxin-NADP+ reductase activity
DEW08_05485	COG1278	Cold shock
DEW08_05510	COG0640	Transcriptional regulator
DEW08_05515	COG0701	Predicted permease
DEW08_05585	COG0747	negative chemotaxis
DEW08_05595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEW08_05615	COG1024	Enoyl-CoA hydratase
DEW08_05615	COG1250	3-hydroxyacyl-CoA dehydrogenase
DEW08_05620	COG0183	Belongs to the thiolase family
DEW08_05625	COG1960	acyl-CoA dehydrogenase activity
DEW08_05630	COG1960	acyl-CoA dehydrogenase activity
DEW08_05690	COG0477	Major facilitator Superfamily
DEW08_05695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DEW08_05695	COG2205	protein histidine kinase activity
DEW08_05720	COG1250	3-hydroxyacyl-CoA dehydrogenase
DEW08_05730	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DEW08_05735	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DEW08_05740	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DEW08_05745	COG1012	belongs to the aldehyde dehydrogenase family
DEW08_05745	COG1454	alcohol dehydrogenase
DEW08_05750	COG2186	Transcriptional regulator
DEW08_05760	COG0247	lactate metabolic process
DEW08_05765	COG1139	Iron-sulfur cluster binding protein
DEW08_05790	COG0848	biopolymer transport protein
DEW08_05805	COG2205	protein histidine kinase activity
DEW08_05805	COG0784	Response regulator, receiver
DEW08_05805	COG2198	Histidine kinase
DEW08_05840	COG0405	Gamma-glutamyltransferase
DEW08_05855	COG4191	Histidine kinase
DEW08_05865	COG2333	competence protein COMEC
DEW08_05865	COG0658	competence protein
DEW08_05870	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DEW08_05875	COG0372	Belongs to the citrate synthase family
DEW08_05895	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DEW08_05900	COG3494	Protein of unknown function (DUF1009)
DEW08_05905	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DEW08_05930	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DEW08_05935	COG0575	Belongs to the CDS family
DEW08_05940	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DEW08_05945	COG0233	cytoplasmic translational termination
DEW08_05950	COG0528	UMP kinase activity
DEW08_05955	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DEW08_05960	COG0052	Belongs to the universal ribosomal protein uS2 family
DEW08_05965	COG0587	DNA-directed DNA polymerase activity
DEW08_05975	COG1404	Belongs to the peptidase S8 family
DEW08_06005	COG1136	(ABC) transporter
DEW08_06015	COG0442	prolyl-tRNA aminoacylation
DEW08_06030	COG0519	Catalyzes the synthesis of GMP from XMP
DEW08_06045	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DEW08_06055	COG1007	ATP synthesis coupled electron transport
DEW08_06070	COG0268	Binds directly to 16S ribosomal RNA
DEW08_06075	COG1024	Enoyl-CoA hydratase
DEW08_06085	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DEW08_06090	COG2226	methyltransferase
DEW08_06095	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DEW08_06110	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DEW08_06115	COG0792	nuclease activity
DEW08_06145	COG1556	Lactate utilization protein
DEW08_06150	COG1139	Iron-sulfur cluster binding protein
DEW08_06155	COG0247	lactate metabolic process
DEW08_06165	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
DEW08_06175	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DEW08_06180	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
DEW08_06205	COG2814	Major facilitator Superfamily
DEW08_06260	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DEW08_06265	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DEW08_06270	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DEW08_06285	COG3685	Protein conserved in bacteria
DEW08_06300	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
DEW08_06320	COG0747	negative chemotaxis
DEW08_06325	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DEW08_06330	COG0180	Tryptophanyl-tRNA synthetase
DEW08_06340	COG2944	sequence-specific DNA binding
DEW08_06350	COG2885	chlorophyll binding
DEW08_06365	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DEW08_06375	COG0302	gtp cyclohydrolase
DEW08_06380	COG2967	ApaG domain
DEW08_06430	COG0784	Response regulator, receiver
DEW08_06430	COG2205	protein histidine kinase activity
DEW08_06440	COG3920	Histidine kinase
DEW08_06445	COG0840	transmembrane signaling receptor activity
DEW08_06445	COG3290	protein histidine kinase activity
DEW08_06465	COG3706	GGDEF domain
DEW08_06470	COG1475	DNA binding
DEW08_06485	COG0840	transmembrane signaling receptor activity
DEW08_06500	COG0840	transmembrane signaling receptor activity
DEW08_06510	COG1396	sequence-specific DNA binding
DEW08_06520	COG5001	Diguanylate cyclase
DEW08_06540	COG0745	RESPONSE REGULATOR receiver
DEW08_06545	COG0784	Response regulator, receiver
DEW08_06545	COG2198	Histidine kinase
DEW08_06545	COG5002	protein histidine kinase activity
DEW08_06610	COG3436	PFAM IS66 Orf2 family protein
DEW08_06615	COG2433	Pfam Transposase IS66
DEW08_06620	COG4974	Belongs to the 'phage' integrase family
DEW08_06625	COG0582	viral genome integration into host DNA
DEW08_06665	COG0784	Response regulator, receiver
DEW08_06665	COG4191	Histidine kinase
DEW08_06710	COG4227	nucleotidyltransferase activity
DEW08_06745	COG1192	Involved in chromosome partitioning
DEW08_06820	COG0697	spore germination
DEW08_06835	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DEW08_06840	COG0071	Belongs to the small heat shock protein (HSP20) family
DEW08_06845	COG0071	Belongs to the small heat shock protein (HSP20) family
DEW08_06890	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DEW08_06935	COG2205	protein histidine kinase activity
DEW08_06935	COG0784	Response regulator, receiver
DEW08_06960	COG0045	succinate-CoA ligase (ADP-forming) activity
DEW08_06960	COG1042	CoA-binding domain protein
DEW08_06960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DEW08_06965	COG4636	protein conserved in cyanobacteria
DEW08_06995	COG1592	Rubrerythrin
DEW08_07015	COG1509	lysine 2,3-aminomutase activity
DEW08_07025	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
DEW08_07030	COG4395	Tim44
DEW08_07040	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
DEW08_07045	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DEW08_07055	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DEW08_07080	COG0237	dephospho-CoA kinase activity
DEW08_07085	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DEW08_07095	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DEW08_07125	COG0357	Ribosomal RNA small subunit methyltransferase G
DEW08_07135	COG1475	DNA binding
DEW08_07205	COG0745	RESPONSE REGULATOR receiver
DEW08_07220	COG3706	GGDEF domain
DEW08_07235	COG0708	Exodeoxyribonuclease III
DEW08_07250	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DEW08_07265	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DEW08_07270	COG0347	Belongs to the P(II) protein family
DEW08_07275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DEW08_07285	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
DEW08_07290	COG0667	Aldo Keto reductase
DEW08_07305	COG4181	ATPase activity
DEW08_07315	COG0670	Belongs to the BI1 family
DEW08_07330	COG3706	GGDEF domain
DEW08_07335	COG0484	heat shock protein binding
DEW08_07340	COG0443	Heat shock 70 kDa protein
DEW08_07360	COG0745	RESPONSE REGULATOR receiver
DEW08_07365	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DEW08_07370	COG1420	regulation of RNA biosynthetic process
DEW08_07375	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DEW08_07380	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DEW08_07385	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DEW08_07395	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DEW08_07450	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DEW08_07455	COG1121	(ABC) transporter
DEW08_07465	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DEW08_07470	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DEW08_07505	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DEW08_07510	COG1733	regulation of RNA biosynthetic process
DEW08_07515	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DEW08_07520	COG0730	response to heat
DEW08_07535	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DEW08_07550	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DEW08_07560	COG1214	PFAM Peptidase M22, glycoprotease
DEW08_07575	COG4957	zinc ion binding
DEW08_07600	COG1702	phosphate starvation-inducible protein PhoH
DEW08_07615	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DEW08_07620	COG1396	sequence-specific DNA binding
DEW08_07630	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DEW08_07635	COG0779	Required for maturation of 30S ribosomal subunits
DEW08_07670	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DEW08_07685	COG1185	polyribonucleotide nucleotidyltransferase activity
DEW08_07700	COG0625	glutathione transferase activity
DEW08_07710	COG0410	ABC transporter
DEW08_07725	COG0559	Belongs to the binding-protein-dependent transport system permease family
DEW08_07735	COG3327	negative regulation of DNA-templated transcription, initiation
DEW08_07765	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
DEW08_07780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DEW08_07790	COG0747	negative chemotaxis
DEW08_07810	COG3162	membrane
DEW08_07825	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DEW08_07835	COG1040	competence protein
DEW08_07840	COG1987	bacterial-type flagellum assembly
DEW08_07845	COG2226	methyltransferase
DEW08_07865	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DEW08_07870	COG0513	Belongs to the DEAD box helicase family
DEW08_07895	COG0653	protein targeting
DEW08_07900	COG0133	tryptophan synthase activity
DEW08_07910	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DEW08_07915	COG0285	dihydrofolate synthase activity
DEW08_07940	COG0187	DNA topoisomerase II activity
DEW08_07945	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DEW08_07950	COG0592	DNA-directed DNA polymerase activity
DEW08_07980	COG0519	Catalyzes the synthesis of GMP from XMP
DEW08_08000	COG2223	nitrite transmembrane transporter activity
DEW08_08035	COG1137	ATPase activity
DEW08_08040	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DEW08_08045	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DEW08_08050	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DEW08_08055	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DEW08_08060	COG0527	aspartate kinase activity
DEW08_08065	COG2070	2-Nitropropane dioxygenase
DEW08_08075	COG0473	3-isopropylmalate dehydrogenase activity
DEW08_08080	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DEW08_08085	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DEW08_08095	COG2890	protein-(glutamine-N5) methyltransferase activity
DEW08_08115	COG0542	response to heat
DEW08_08120	COG3813	Protein conserved in bacteria
DEW08_08130	COG0840	transmembrane signaling receptor activity
DEW08_08135	COG5265	(ABC) transporter
DEW08_08145	COG1703	isobutyryl-CoA mutase activity
DEW08_08155	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DEW08_08160	COG2137	regulation of response to DNA damage stimulus
DEW08_08165	COG0842	Transport permease protein
DEW08_08170	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DEW08_08175	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DEW08_08180	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DEW08_08190	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DEW08_08200	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DEW08_08205	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DEW08_08210	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DEW08_08210	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
DEW08_08220	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DEW08_08230	COG2205	protein histidine kinase activity
DEW08_08235	COG0745	RESPONSE REGULATOR receiver
DEW08_08245	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
DEW08_08250	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DEW08_08265	COG0739	heme binding
DEW08_08385	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DEW08_08390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DEW08_08400	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DEW08_08410	COG0824	Thioesterase
DEW08_08445	COG1028	Short-chain dehydrogenase reductase Sdr
DEW08_08460	COG4566	intracellular signal transduction
DEW08_08475	COG0604	alcohol dehydrogenase
DEW08_08480	COG0583	DNA-binding transcription factor activity
DEW08_08495	COG2199	diguanylate cyclase activity
DEW08_08495	COG2203	Gaf domain
DEW08_08495	COG2200	EAL domain
DEW08_08505	COG0444	Belongs to the ABC transporter superfamily
DEW08_08515	COG0601	transmembrane transport
DEW08_08570	COG0776	regulation of translation
DEW08_08580	COG2423	ornithine cyclodeaminase activity
DEW08_08605	COG0135	phosphoribosylanthranilate isomerase activity
DEW08_08610	COG0745	RESPONSE REGULATOR receiver
DEW08_08610	COG3706	GGDEF domain
DEW08_08615	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DEW08_08625	COG1741	Belongs to the pirin family
DEW08_08655	COG0271	Belongs to the BolA IbaG family
DEW08_08670	COG0517	IMP dehydrogenase activity
DEW08_08675	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DEW08_08690	COG4974	Belongs to the 'phage' integrase family
DEW08_08695	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DEW08_08700	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DEW08_08705	COG0825	malonyl-CoA metabolic process
DEW08_08715	COG1442	glycosyl transferase family 8
DEW08_08715	COG1216	Glycosyl transferase, family 2
DEW08_08730	COG0840	transmembrane signaling receptor activity
DEW08_08735	COG0438	transferase activity, transferring glycosyl groups
DEW08_08750	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DEW08_08770	COG0489	protein tyrosine kinase activity
DEW08_08770	COG3206	protein involved in exopolysaccharide biosynthesis
DEW08_08785	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
DEW08_08805	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DEW08_08810	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DEW08_08830	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DEW08_08860	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DEW08_08865	COG2171	N-acyltransferase activity
DEW08_08900	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DEW08_08905	COG0228	four-way junction DNA binding
DEW08_08910	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DEW08_08915	COG0336	Belongs to the RNA methyltransferase TrmD family
DEW08_08920	COG0335	large ribosomal subunit rRNA binding
DEW08_08925	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DEW08_08930	COG0594	ribonuclease P activity
DEW08_08935	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DEW08_08940	COG0706	membrane insertase activity
DEW08_08945	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DEW08_08960	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DEW08_08970	COG0598	Magnesium transport protein CorA
DEW08_08995	COG1322	Protein conserved in bacteria
DEW08_09010	COG1028	Short-chain dehydrogenase reductase Sdr
DEW08_09020	COG0655	NAD(P)H dehydrogenase (quinone) activity
DEW08_09025	COG0156	8-amino-7-oxononanoate synthase activity
DEW08_09030	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DEW08_09045	COG5001	Diguanylate cyclase
DEW08_09060	COG0583	DNA-binding transcription factor activity
DEW08_09075	COG1024	Enoyl-CoA hydratase
DEW08_09120	COG1192	Involved in chromosome partitioning
DEW08_09155	COG4191	Histidine kinase
DEW08_09170	COG2176	DNA-directed DNA polymerase activity
DEW08_09170	COG5002	protein histidine kinase activity
DEW08_09175	COG0745	RESPONSE REGULATOR receiver
DEW08_09185	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DEW08_09190	COG2917	probably involved in intracellular septation
DEW08_09200	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DEW08_09230	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DEW08_09235	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DEW08_09245	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DEW08_09250	COG1187	pseudouridine synthase activity
DEW08_09255	COG4172	Belongs to the ABC transporter superfamily
DEW08_09260	COG4239	(ABC) transporter, permease
DEW08_09265	COG4174	ABC transporter (Permease)
DEW08_09270	COG4166	transmembrane transport
DEW08_09275	COG4166	transmembrane transport
DEW08_09280	COG0318	PFAM AMP-dependent synthetase and ligase
DEW08_09290	COG1254	Belongs to the acylphosphatase family
DEW08_09310	COG2022	thiamine diphosphate biosynthetic process
DEW08_09320	COG2022	thiamine diphosphate biosynthetic process
DEW08_09320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DEW08_09325	COG2239	Acts as a magnesium transporter
DEW08_09365	COG5433	transposase activity
DEW08_09385	COG0583	DNA-binding transcription factor activity
DEW08_09440	COG0745	RESPONSE REGULATOR receiver
DEW08_09445	COG2766	serine protein kinase
DEW08_09450	COG2718	Belongs to the UPF0229 family
DEW08_09455	COG2719	SpoVR family
DEW08_09460	COG1643	Atp-dependent helicase
DEW08_09475	COG0745	RESPONSE REGULATOR receiver
DEW08_09505	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DEW08_09520	COG2267	carboxylic ester hydrolase activity
DEW08_09525	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DEW08_09530	COG2030	dehydratase
DEW08_09535	COG0196	riboflavin kinase activity
DEW08_09545	COG0628	permease
DEW08_09575	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DEW08_09600	COG1686	Belongs to the peptidase S11 family
DEW08_09615	COG2198	Histidine kinase
DEW08_09615	COG0784	Response regulator, receiver
DEW08_09615	COG2205	protein histidine kinase activity
DEW08_09620	COG2205	protein histidine kinase activity
DEW08_09635	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DEW08_09640	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DEW08_09645	COG0277	FAD linked oxidase domain protein
DEW08_09650	COG0277	FAD linked oxidase domain protein
DEW08_09655	COG0247	lactate metabolic process
DEW08_09680	COG1454	alcohol dehydrogenase
DEW08_09685	COG1960	acyl-CoA dehydrogenase activity
DEW08_09695	COG1192	Involved in chromosome partitioning
DEW08_09700	COG0009	L-threonylcarbamoyladenylate synthase
DEW08_09710	COG0277	FAD linked oxidase domain protein
DEW08_09715	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DEW08_09725	COG0559	Belongs to the binding-protein-dependent transport system permease family
DEW08_09730	COG0101	tRNA pseudouridine synthase activity
DEW08_09735	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DEW08_09740	COG0242	peptide deformylase activity
DEW08_09755	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DEW08_09760	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DEW08_09785	COG3719	Belongs to the RNase T2 family
DEW08_09795	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DEW08_09800	COG0569	domain protein
DEW08_09840	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DEW08_09865	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DEW08_09870	COG4651	solute:proton antiporter activity
DEW08_09870	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DEW08_09895	COG0482	sulfurtransferase activity
DEW08_09905	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
DEW08_09920	COG1045	serine acetyltransferase
DEW08_09925	COG2945	thiolester hydrolase activity
DEW08_09940	COG4106	trans-aconitate 2-methyltransferase activity
DEW08_09955	COG1280	lysine exporter protein (LysE YggA)
DEW08_09965	COG1663	tetraacyldisaccharide 4'-kinase activity
DEW08_09970	COG1519	Transferase
DEW08_09985	COG0438	transferase activity, transferring glycosyl groups
DEW08_09995	COG1597	lipid kinase activity
DEW08_10005	COG0312	modulator of DNA gyrase
DEW08_10030	COG2264	protein methyltransferase activity
DEW08_10050	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DEW08_10070	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DEW08_10075	COG0860	N-Acetylmuramoyl-L-alanine amidase
DEW08_10080	COG1530	ribonuclease E activity
DEW08_10205	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DEW08_10230	COG1940	carbohydrate kinase activity
DEW08_10300	COG5433	transposase activity
DEW08_10320	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DEW08_10340	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DEW08_10345	COG0081	regulation of translation
DEW08_10350	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DEW08_10355	COG0222	ribosome binding
DEW08_10365	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DEW08_10375	COG0049	tRNA binding
DEW08_10385	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DEW08_10390	COG0051	transcription antitermination factor activity, RNA binding
DEW08_10400	COG0088	Forms part of the polypeptide exit tunnel
DEW08_10410	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DEW08_10415	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DEW08_10420	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DEW08_10425	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DEW08_10430	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DEW08_10435	COG0255	Belongs to the universal ribosomal protein uL29 family
DEW08_10440	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DEW08_10445	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DEW08_10450	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DEW08_10460	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DEW08_10465	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DEW08_10470	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DEW08_10485	COG1841	ribosomal large subunit assembly
DEW08_10490	COG0200	Binds to the 23S rRNA
DEW08_10495	COG0201	protein transport
DEW08_10500	COG0563	adenylate kinase activity
DEW08_10525	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DEW08_10555	COG0071	Belongs to the small heat shock protein (HSP20) family
DEW08_10565	COG0254	rRNA binding
DEW08_10575	COG2311	Membrane
DEW08_10585	COG1671	Belongs to the UPF0178 family
DEW08_10590	COG0488	(ABC) transporter
DEW08_10635	COG1410	methionine synthase
DEW08_10635	COG0646	methionine synthase
DEW08_10670	COG3706	GGDEF domain
DEW08_10675	COG0243	molybdopterin cofactor binding
DEW08_10700	COG4566	intracellular signal transduction
DEW08_10710	COG0745	RESPONSE REGULATOR receiver
DEW08_10715	COG0784	Response regulator, receiver
DEW08_10715	COG4191	Histidine kinase
DEW08_10725	COG0745	RESPONSE REGULATOR receiver
DEW08_10725	COG3706	GGDEF domain
DEW08_10740	COG3108	Peptidase M15
DEW08_10760	COG0583	DNA-binding transcription factor activity
DEW08_10765	COG0697	spore germination
DEW08_10780	COG0418	dihydroorotase activity
DEW08_10785	COG2755	lipolytic protein G-D-S-L family
DEW08_10785	COG0657	acetylesterase activity
DEW08_10790	COG2226	methyltransferase
DEW08_10795	COG1570	exodeoxyribonuclease VII activity
DEW08_10810	COG0590	tRNA wobble adenosine to inosine editing
DEW08_10815	COG1187	pseudouridine synthase activity
DEW08_10820	COG0742	ribosomal rna small subunit methyltransferase
DEW08_10835	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DEW08_10855	COG0612	Peptidase, M16
DEW08_10860	COG0612	Peptidase, M16
DEW08_10870	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DEW08_10885	COG1858	cytochrome C peroxidase
DEW08_10890	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DEW08_10895	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DEW08_10910	COG0754	glutathionylspermidine amidase activity
DEW08_10920	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
DEW08_10925	COG3243	poly(R)-hydroxyalkanoic acid synthase
DEW08_10930	COG0183	Belongs to the thiolase family
DEW08_10935	COG1028	Short-chain dehydrogenase reductase Sdr
DEW08_10945	COG2814	Major facilitator Superfamily
DEW08_10950	COG0583	DNA-binding transcription factor activity
DEW08_10960	COG5001	Diguanylate cyclase
DEW08_10960	COG3300	MHYT domain
DEW08_10965	COG0012	GTP binding
DEW08_10970	COG0193	aminoacyl-tRNA hydrolase activity
DEW08_10975	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DEW08_10985	COG1346	cytolysis
DEW08_10990	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DEW08_11030	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DEW08_11035	COG1073	alpha beta
DEW08_11060	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DEW08_11080	COG0726	polysaccharide deacetylase
DEW08_11085	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DEW08_11095	COG2989	Protein conserved in bacteria
DEW08_11100	COG3108	Peptidase M15
DEW08_11140	COG0511	ligase activity, forming carbon-carbon bonds
DEW08_11145	COG0439	Biotin carboxylase
DEW08_11175	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DEW08_11190	COG0432	Pfam Uncharacterised protein family UPF0047
DEW08_11205	COG1280	lysine exporter protein (LysE YggA)
DEW08_11210	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DEW08_11220	COG2205	protein histidine kinase activity
DEW08_11225	COG0523	cobalamin synthesis protein
DEW08_11230	COG0735	belongs to the Fur family
DEW08_11235	COG0415	Belongs to the DNA photolyase family
DEW08_11245	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DEW08_11250	COG1201	RNA secondary structure unwinding
DEW08_11270	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DEW08_11290	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DEW08_11315	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DEW08_11320	COG0746	molybdenum cofactor guanylyltransferase activity
DEW08_11345	COG0243	molybdopterin cofactor binding
DEW08_11345	COG3383	formate dehydrogenase (NAD+) activity
DEW08_11350	COG0437	4 iron, 4 sulfur cluster binding
DEW08_11370	COG0235	Class ii aldolase
DEW08_11385	COG3384	dioxygenase
DEW08_11390	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DEW08_11395	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DEW08_11400	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DEW08_11405	COG0356	it plays a direct role in the translocation of protons across the membrane
DEW08_11415	COG1999	signal sequence binding
DEW08_11420	COG0840	transmembrane signaling receptor activity
DEW08_11430	COG0850	regulation of cytokinetic process
DEW08_11435	COG2894	cell division
DEW08_11455	COG0840	transmembrane signaling receptor activity
DEW08_11465	COG4948	Mandelate Racemase Muconate Lactonizing
DEW08_11480	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DEW08_11505	COG5554	nitrogen fixation
DEW08_11520	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DEW08_11530	COG0583	DNA-binding transcription factor activity
DEW08_11560	COG1131	(ABC) transporter
DEW08_11570	COG0842	Transport permease protein
DEW08_11575	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
DEW08_11595	COG2030	dehydratase
DEW08_11610	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DEW08_11640	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DEW08_11650	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
DEW08_11660	COG4786	Flagellar basal body rod
DEW08_11665	COG4786	Flagellar basal body rod
DEW08_11695	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
DEW08_11710	COG1086	Polysaccharide biosynthesis protein
DEW08_11750	COG0717	Belongs to the dCTP deaminase family
DEW08_11755	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DEW08_11770	COG0693	protein deglycase activity
DEW08_11775	COG2197	response regulator
DEW08_11780	COG2197	response regulator
DEW08_11795	COG0829	nickel cation binding
DEW08_11820	COG0831	urea catabolic process
DEW08_11825	COG0832	Belongs to the urease beta subunit family
DEW08_11830	COG0804	urea catabolic process
DEW08_11840	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
DEW08_11845	COG0830	nickel cation binding
DEW08_11850	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DEW08_11865	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DEW08_11875	COG0560	Phosphoserine phosphatase
DEW08_11875	COG3830	Belongs to the UPF0237 family
DEW08_11880	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DEW08_11885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DEW08_11890	COG0028	Belongs to the TPP enzyme family
DEW08_11940	COG5433	transposase activity
DEW08_11950	COG2226	methyltransferase
DEW08_11955	COG2205	protein histidine kinase activity
DEW08_11960	COG0745	RESPONSE REGULATOR receiver
DEW08_11965	COG1846	Transcriptional regulator
DEW08_11975	COG1024	Enoyl-CoA hydratase
DEW08_11985	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DEW08_11995	COG2313	pseudouridylate synthase activity
DEW08_12015	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DEW08_12015	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DEW08_12020	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DEW08_12025	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DEW08_12040	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DEW08_12060	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DEW08_12065	COG0416	fatty acid biosynthetic process
DEW08_12070	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DEW08_12135	COG0318	PFAM AMP-dependent synthetase and ligase
DEW08_12180	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
DEW08_12185	COG2814	Major facilitator Superfamily
DEW08_12190	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DEW08_12205	COG1755	Isoprenylcysteine carboxyl methyltransferase
DEW08_12215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DEW08_12230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DEW08_12240	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DEW08_12280	COG4221	oxidoreductase activity
DEW08_12285	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DEW08_12290	COG3932	Exopolysaccharide synthesis, ExoD
DEW08_12295	COG0488	(ABC) transporter
DEW08_12300	COG0105	UTP biosynthetic process
DEW08_12315	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DEW08_12320	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DEW08_12335	COG0628	permease
DEW08_12345	COG1028	Short-chain dehydrogenase reductase Sdr
DEW08_12360	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DEW08_12365	COG0248	Ppx GppA phosphatase
DEW08_12380	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DEW08_12405	COG3290	protein histidine kinase activity
DEW08_12405	COG0840	transmembrane signaling receptor activity
DEW08_12410	COG0668	transmembrane transport
DEW08_12425	COG2853	Lipoprotein
DEW08_12465	COG1230	cation diffusion facilitator family transporter
DEW08_12475	COG1765	OsmC-like protein
DEW08_12480	COG2076	Multidrug Resistance protein
DEW08_12485	COG5433	transposase activity
DEW08_12500	COG5433	transposase activity
DEW08_12505	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DEW08_12510	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DEW08_12515	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
DEW08_12525	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DEW08_12530	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DEW08_12535	COG0242	peptide deformylase activity
DEW08_12560	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
DEW08_12580	COG4120	Belongs to the binding-protein-dependent transport system permease family
DEW08_12585	COG0410	ABC transporter
DEW08_12595	COG0489	protein tyrosine kinase activity
DEW08_12605	COG0330	HflC and HflK could
DEW08_12615	COG3344	reverse transcriptase
DEW08_12660	COG1396	sequence-specific DNA binding
DEW08_12695	COG2951	lytic endotransglycosylase activity
DEW08_12705	COG0704	Plays a role in the regulation of phosphate uptake
DEW08_12760	COG2068	MobA-Related Protein
DEW08_12765	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DEW08_12825	COG3956	TIGRFAM MazG family protein
DEW08_12835	COG0321	lipoyl(octanoyl) transferase activity
DEW08_12835	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DEW08_12840	COG0084	hydrolase, TatD family'
DEW08_12845	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DEW08_12850	COG0470	DNA polymerase III
DEW08_12855	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DEW08_12860	COG1686	Belongs to the peptidase S11 family
DEW08_12890	COG0525	valine-tRNA ligase activity
DEW08_12900	COG1538	Outer membrane efflux protein
DEW08_12910	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DEW08_12940	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DEW08_12945	COG0494	nUDIX hydrolase
DEW08_12960	COG2897	thiosulfate sulfurtransferase activity
DEW08_12975	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DEW08_12980	COG1126	abc transporter atp-binding protein
DEW08_12985	COG0765	amino acid transport
DEW08_12990	COG4597	amino acid ABC transporter
DEW08_12995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DEW08_13000	COG0626	cystathionine gamma-synthase activity
DEW08_13005	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DEW08_13040	COG1136	(ABC) transporter
DEW08_13045	COG1566	PFAM secretion protein HlyD family protein
DEW08_13065	COG0123	including yeast histone deacetylase and acetoin utilization protein
DEW08_13075	COG1116	anion transmembrane transporter activity
DEW08_13080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DEW08_13085	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DEW08_13095	COG0483	inositol monophosphate 1-phosphatase activity
DEW08_13110	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DEW08_13115	COG1923	regulation of RNA biosynthetic process
DEW08_13125	COG2204	response regulator
DEW08_13160	COG1058	Belongs to the CinA family
DEW08_13160	COG1546	Belongs to the CinA family
DEW08_13165	COG2867	negative regulation of translational initiation
DEW08_13170	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DEW08_13180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DEW08_13190	COG0508	dehydrogenase complex catalyzes the overall conversion of
DEW08_13195	COG0508	dehydrogenase complex catalyzes the overall conversion of
DEW08_13195	COG0022	dehydrogenase e1 component
DEW08_13200	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DEW08_13215	COG1607	acyl-coa hydrolase
DEW08_13230	COG2267	carboxylic ester hydrolase activity
DEW08_13240	COG0513	Belongs to the DEAD box helicase family
DEW08_13250	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
DEW08_13260	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DEW08_13270	COG2261	transglycosylase associated protein
DEW08_13275	COG0784	Response regulator, receiver
DEW08_13290	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DEW08_13300	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DEW08_13300	COG1116	anion transmembrane transporter activity
DEW08_13315	COG0175	sulfate reduction
DEW08_13340	COG3239	Fatty acid desaturase
DEW08_13370	COG4191	Histidine kinase
DEW08_13370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DEW08_13385	COG3437	response regulator, receiver
DEW08_13385	COG0784	Response regulator, receiver
DEW08_13410	COG0140	phosphoribosyl-ATP diphosphatase activity
DEW08_13415	COG0840	transmembrane signaling receptor activity
DEW08_13415	COG3290	protein histidine kinase activity
DEW08_13420	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DEW08_13490	COG0288	reversible hydration of carbon dioxide
DEW08_13510	COG0205	6-phosphofructokinase activity
DEW08_13525	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DEW08_13530	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DEW08_13535	COG2199	diguanylate cyclase activity
DEW08_13535	COG2200	EAL domain
DEW08_13560	COG0114	fumarate hydratase activity
DEW08_13580	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DEW08_13585	COG2815	serine threonine protein kinase
DEW08_13585	COG0515	serine threonine protein kinase
DEW08_13610	COG2010	Cytochrome c
DEW08_13615	COG2308	Evidence 4 Homologs of previously reported genes of
DEW08_13615	COG2307	Protein conserved in bacteria
DEW08_13620	COG1305	Transglutaminase-like
DEW08_13625	COG0745	RESPONSE REGULATOR receiver
DEW08_13630	COG4191	Histidine kinase
DEW08_13635	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DEW08_13640	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DEW08_13645	COG0058	SHG alpha-glucan phosphorylase activity
DEW08_13685	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DEW08_13710	COG1846	Transcriptional regulator
DEW08_13715	COG1024	Enoyl-CoA hydratase
DEW08_13720	COG1597	lipid kinase activity
DEW08_13725	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DEW08_13730	COG0113	porphobilinogen synthase activity
DEW08_13735	COG2813	Specifically methylates the guanine in position
DEW08_13740	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DEW08_13745	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DEW08_13760	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DEW08_13765	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DEW08_13780	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DEW08_13790	COG0360	Binds together with S18 to 16S ribosomal RNA
DEW08_13795	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DEW08_13805	COG0359	binds to the 23S rRNA
DEW08_13810	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DEW08_13815	COG0305	Participates in initiation and elongation during chromosome replication
DEW08_13820	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DEW08_13825	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DEW08_13830	COG1127	ABC transporter
DEW08_13845	COG0024	Methionine aminopeptidase
DEW08_13860	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DEW08_13865	COG1028	Short-chain dehydrogenase reductase Sdr
DEW08_13875	COG4566	intracellular signal transduction
DEW08_13875	COG0745	RESPONSE REGULATOR receiver
DEW08_13885	COG1160	GTP binding
DEW08_13900	COG2197	response regulator
DEW08_13910	COG2197	response regulator
DEW08_13935	COG2723	6-phospho-beta-galactosidase activity
DEW08_13945	COG2204	response regulator
DEW08_13950	COG3706	GGDEF domain
DEW08_13950	COG0745	RESPONSE REGULATOR receiver
DEW08_13965	COG1492	cobalamin metabolic process
DEW08_14025	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DEW08_14025	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DEW08_14060	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DEW08_14065	COG1393	Belongs to the ArsC family
DEW08_14070	COG2890	protein-(glutamine-N5) methyltransferase activity
DEW08_14100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DEW08_14125	COG1366	Belongs to the anti-sigma-factor antagonist family
DEW08_14130	COG2770	Histidine kinase
DEW08_14130	COG2208	phosphoserine phosphatase activity
DEW08_14195	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DEW08_14195	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DEW08_14200	COG0371	Dehydrogenase
DEW08_14205	COG1494	fructose-1,6-bisphosphatase
DEW08_14215	COG0436	Aminotransferase
DEW08_14240	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DEW08_14240	COG2885	chlorophyll binding
DEW08_14245	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DEW08_14250	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DEW08_14255	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DEW08_14260	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DEW08_14270	COG1024	Enoyl-CoA hydratase
DEW08_14275	COG1832	CoA-binding protein
DEW08_14285	COG1028	Short-chain dehydrogenase reductase Sdr
DEW08_14315	COG2855	membrane
DEW08_14330	COG1162	GTPase activity
DEW08_14345	COG4191	Histidine kinase
DEW08_14350	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DEW08_14365	COG0154	amidase activity
DEW08_14370	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DEW08_14380	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DEW08_14390	COG4633	Protein conserved in bacteria
DEW08_14410	COG0583	DNA-binding transcription factor activity
DEW08_14415	COG0540	Belongs to the ATCase OTCase family
DEW08_14420	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DEW08_14435	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
DEW08_14440	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DEW08_14445	COG1028	Short-chain dehydrogenase reductase Sdr
DEW08_14475	COG0598	Magnesium transport protein CorA
DEW08_14490	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DEW08_14490	COG2010	Cytochrome c
DEW08_14505	COG0538	isocitrate dehydrogenase activity
DEW08_14520	COG3932	Exopolysaccharide synthesis, ExoD
DEW08_14540	COG0473	3-isopropylmalate dehydrogenase activity
DEW08_14560	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DEW08_14575	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DEW08_14585	COG0758	DNA mediated transformation
DEW08_14605	COG0557	exoribonuclease II activity
DEW08_14610	COG0793	Belongs to the peptidase S41A family
DEW08_14615	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DEW08_14620	COG0745	RESPONSE REGULATOR receiver
DEW08_14620	COG3706	GGDEF domain
DEW08_14625	COG0784	Response regulator, receiver
DEW08_14630	COG4251	negative regulation of phosphorylation
DEW08_14635	COG3447	MASE1 domain protein
DEW08_14635	COG5002	protein histidine kinase activity
DEW08_14635	COG5001	Diguanylate cyclase
DEW08_14655	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DEW08_14660	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
DEW08_14690	COG3685	Protein conserved in bacteria
DEW08_14725	COG1573	uracil-dna glycosylase
DEW08_14730	COG2154	pterin-4-alpha-carbinolamine dehydratase
DEW08_14740	COG0121	glutamine amidotransferase
DEW08_14760	COG3179	chitinase
DEW08_14790	COG2860	membrane
DEW08_14795	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
DEW08_14800	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
DEW08_14815	COG5420	small protein containing a coiled-coil domain
DEW08_14885	COG0644	oxidoreductase
DEW08_14925	COG1278	Cold shock
DEW08_14930	COG1252	NADH dehydrogenase
DEW08_14935	COG1902	pentaerythritol trinitrate reductase activity
DEW08_14950	COG0328	RNA-DNA hybrid ribonuclease activity
DEW08_14950	COG0406	alpha-ribazole phosphatase activity
DEW08_14955	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DEW08_14970	COG1058	Belongs to the CinA family
DEW08_14970	COG1546	Belongs to the CinA family
DEW08_14980	COG0024	Methionine aminopeptidase
DEW08_14985	COG2003	Belongs to the UPF0758 family
DEW08_15000	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DEW08_15020	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DEW08_15025	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DEW08_15040	COG2258	MOSC domain
DEW08_15045	COG0840	transmembrane signaling receptor activity
DEW08_15050	COG0004	ammonium transporteR
DEW08_15065	COG0047	phosphoribosylformylglycinamidine synthase activity
DEW08_15070	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DEW08_15080	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DEW08_15085	COG2962	Rard protein
DEW08_15095	COG1902	pentaerythritol trinitrate reductase activity
DEW08_15105	COG0583	DNA-binding transcription factor activity
DEW08_15110	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DEW08_15125	COG3800	Transcriptional regulator
DEW08_15125	COG1396	sequence-specific DNA binding
DEW08_15135	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DEW08_15180	COG5433	transposase activity
DEW08_15190	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DEW08_15200	COG0463	Glycosyl transferase, family 2
DEW08_15210	COG3012	SEC-C Motif Domain Protein
DEW08_15220	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DEW08_15245	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DEW08_15250	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DEW08_15255	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DEW08_15270	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DEW08_15280	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DEW08_15280	COG2010	Cytochrome c
DEW08_15295	COG0799	negative regulation of ribosome biogenesis
DEW08_15300	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DEW08_15315	COG0793	Belongs to the peptidase S41A family
DEW08_15325	COG1051	belongs to the nudix hydrolase family
DEW08_15340	COG2198	Histidine kinase
DEW08_15340	COG0643	Histidine kinase
DEW08_15345	COG0835	chemotaxis
DEW08_15350	COG0840	transmembrane signaling receptor activity
DEW08_15355	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DEW08_15360	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
DEW08_15365	COG2201	protein-glutamate methylesterase activity
DEW08_15370	COG0840	transmembrane signaling receptor activity
DEW08_15375	COG1366	Belongs to the anti-sigma-factor antagonist family
DEW08_15385	COG3706	GGDEF domain
DEW08_15385	COG0745	RESPONSE REGULATOR receiver
DEW08_15390	COG0745	RESPONSE REGULATOR receiver
DEW08_15390	COG3706	GGDEF domain
DEW08_15420	COG0745	RESPONSE REGULATOR receiver
DEW08_15435	COG4191	Histidine kinase
DEW08_15435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DEW08_15470	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DEW08_15480	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DEW08_15500	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DEW08_15510	COG4974	Belongs to the 'phage' integrase family
DEW08_15530	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DEW08_15550	COG4106	trans-aconitate 2-methyltransferase activity
DEW08_15565	COG0126	phosphoglycerate kinase activity
DEW08_15590	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DEW08_15595	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DEW08_15600	COG3474	cytochrome
DEW08_15605	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DEW08_15620	COG2816	NAD+ diphosphatase activity
DEW08_15660	COG0142	geranyltranstransferase activity
DEW08_15670	COG2890	protein-(glutamine-N5) methyltransferase activity
DEW08_15675	COG1247	-acetyltransferase
DEW08_15680	COG3655	Transcriptional regulator
DEW08_15715	COG0752	glycyl-tRNA synthetase alpha subunit
DEW08_15765	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DEW08_15770	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DEW08_15775	COG0698	ribose 5-phosphate isomerase
DEW08_15795	COG3685	Protein conserved in bacteria
DEW08_15825	COG4191	Histidine kinase
DEW08_15825	COG0784	Response regulator, receiver
DEW08_15840	COG1752	Esterase of the alpha-beta hydrolase superfamily
DEW08_15855	COG0840	transmembrane signaling receptor activity
DEW08_15890	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
DEW08_15910	COG3023	N-Acetylmuramoyl-L-alanine amidase
DEW08_15915	COG4636	protein conserved in cyanobacteria
DEW08_15925	COG2001	Belongs to the MraZ family
DEW08_15945	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DEW08_15955	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DEW08_15960	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DEW08_15970	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DEW08_15980	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DEW08_15985	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DEW08_15990	COG1181	Belongs to the D-alanine--D-alanine ligase family
DEW08_15995	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DEW08_16000	COG0849	cell division
DEW08_16005	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DEW08_16035	COG0497	DNA recombination
DEW08_16040	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DEW08_16055	COG0745	RESPONSE REGULATOR receiver
DEW08_16060	COG0006	proline dipeptidase activity
DEW08_16060	COG0006	proline dipeptidase activity
DEW08_16070	COG2264	protein methyltransferase activity
DEW08_16095	COG2197	response regulator
DEW08_16100	COG2197	response regulator
DEW08_16140	COG1238	metal cluster binding
DEW08_16165	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
DEW08_16175	COG2205	protein histidine kinase activity
DEW08_16180	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DEW08_16190	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DEW08_16200	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DEW08_16220	COG1674	ftsk spoiiie
DEW08_16240	COG4191	Histidine kinase
DEW08_16260	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DEW08_16265	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DEW08_16285	COG1522	sequence-specific DNA binding
DEW08_16290	COG3660	Nucleoside-diphosphate-sugar epimerase
DEW08_16315	COG0492	ferredoxin-NADP+ reductase activity
DEW08_16320	COG0783	Belongs to the Dps family
DEW08_16325	COG0840	transmembrane signaling receptor activity
DEW08_16330	COG0840	transmembrane signaling receptor activity
DEW08_16335	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DEW08_16400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DEW08_16425	COG2009	succinate dehydrogenase
DEW08_16435	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DEW08_16450	COG0679	Auxin Efflux Carrier
DEW08_16455	COG0840	transmembrane signaling receptor activity
DEW08_16460	COG1199	ATP-dependent helicase activity
DEW08_16460	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DEW08_16470	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DEW08_16480	COG2076	Multidrug Resistance protein
DEW08_16485	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
DEW08_16505	COG0039	L-malate dehydrogenase activity
DEW08_16510	COG0045	succinate-CoA ligase (ADP-forming) activity
DEW08_16515	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DEW08_16525	COG0508	dehydrogenase complex catalyzes the overall conversion of
DEW08_16540	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DEW08_16550	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
DEW08_16560	COG2301	Belongs to the HpcH HpaI aldolase family
DEW08_16600	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DEW08_16615	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DEW08_16625	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DEW08_16660	COG0625	glutathione transferase activity
DEW08_16670	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DEW08_16680	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DEW08_16710	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DEW08_16715	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DEW08_16725	COG0167	dihydroorotate dehydrogenase activity
DEW08_16800	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DEW08_16895	COG0625	glutathione transferase activity
DEW08_16910	COG0395	ABC-type sugar transport system, permease component
DEW08_16950	COG1285	pathogenesis
DEW08_16995	COG2835	tetraacyldisaccharide 4'-kinase activity
DEW08_17000	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DEW08_17010	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
DEW08_17020	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DEW08_17075	COG0138	bifunctional purine biosynthesis protein purh
DEW08_17090	COG2264	protein methyltransferase activity
DEW08_17100	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DEW08_17100	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DEW08_17115	COG0501	Belongs to the peptidase M48B family
DEW08_17120	COG5508	conserved small protein
DEW08_17140	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DEW08_17160	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DEW08_17170	COG0539	negative regulation of cytoplasmic translation
DEW08_17180	COG2205	protein histidine kinase activity
DEW08_17185	COG0745	RESPONSE REGULATOR receiver
DEW08_17225	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DEW08_17255	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DEW08_17260	COG0181	hydroxymethylbilane synthase activity
DEW08_17275	COG1301	dicarboxylic acid transport
DEW08_17305	COG4251	negative regulation of phosphorylation
DEW08_17305	COG5001	Diguanylate cyclase
DEW08_17305	COG2203	Gaf domain
DEW08_17305	COG3706	GGDEF domain
DEW08_17310	COG0784	Response regulator, receiver
DEW08_17310	COG5002	protein histidine kinase activity
DEW08_17310	COG2205	protein histidine kinase activity
DEW08_17320	COG0579	oxidoreductase
DEW08_17325	COG0071	Belongs to the small heat shock protein (HSP20) family
DEW08_17350	COG0489	protein tyrosine kinase activity
DEW08_17365	COG2885	chlorophyll binding
DEW08_17420	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DEW08_17430	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
DEW08_17435	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DEW08_17450	COG0459	protein refolding
DEW08_17455	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DEW08_17460	COG5425	PFAM Usg family protein
DEW08_17465	COG1612	heme a metabolic process
DEW08_17480	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DEW08_17495	COG4608	Belongs to the ABC transporter superfamily
DEW08_17500	COG0693	protein deglycase activity
DEW08_17505	COG2224	Isocitrate lyase
DEW08_17530	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DEW08_17535	COG3437	response regulator, receiver
DEW08_17535	COG0784	Response regulator, receiver
DEW08_17545	COG0668	transmembrane transport
DEW08_17555	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DEW08_17560	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DEW08_17560	COG0674	pyruvate-flavodoxin oxidoreductase activity
DEW08_17565	COG1013	pyruvate-flavodoxin oxidoreductase activity
DEW08_17575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DEW08_17585	COG2205	protein histidine kinase activity
DEW08_17620	COG0802	atpase or kinase
DEW08_17630	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DEW08_17660	COG4235	cytochrome complex assembly
DEW08_17665	COG3088	subunit of a heme lyase
DEW08_17670	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DEW08_17675	COG1138	Cytochrome C-type biogenesis protein
DEW08_17680	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
DEW08_17690	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DEW08_17700	COG2154	pterin-4-alpha-carbinolamine dehydratase
DEW08_17715	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DEW08_17720	COG1872	DUF167
DEW08_17735	COG0386	Belongs to the glutathione peroxidase family
DEW08_17760	COG2985	domain, Protein
DEW08_17775	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DEW08_17780	COG1573	uracil-dna glycosylase
DEW08_17790	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DEW08_17805	COG0697	spore germination
DEW08_17825	COG0137	argininosuccinate synthase activity
DEW08_17840	COG2202	Pas domain
DEW08_17840	COG2205	protein histidine kinase activity
DEW08_17845	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DEW08_17855	COG1595	DNA-templated transcription, initiation
DEW08_17905	COG0861	Integral membrane protein TerC family
DEW08_17915	COG0477	Major facilitator Superfamily
DEW08_17920	COG0583	DNA-binding transcription factor activity
DEW08_17940	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DEW08_17945	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DEW08_17950	COG0501	Belongs to the peptidase M48B family
DEW08_17965	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DEW08_17970	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DEW08_17975	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DEW08_17980	COG0072	phenylalanine-tRNA ligase activity
DEW08_18000	COG0583	DNA-binding transcription factor activity
DEW08_18010	COG0481	GTPase activity
DEW08_18015	COG0297	glycogen (starch) synthase activity
DEW08_18025	COG0004	ammonium transporteR
DEW08_18060	COG1595	DNA-templated transcription, initiation
DEW08_18065	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DEW08_18080	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DEW08_18090	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DEW08_18100	COG0756	dUTP diphosphatase activity
DEW08_18105	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DEW08_18110	COG2204	response regulator
DEW08_18115	COG1278	Cold shock
DEW08_18130	COG0745	RESPONSE REGULATOR receiver
DEW08_18135	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DEW08_18145	COG0573	inorganic phosphate transmembrane transporter activity
DEW08_18150	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DEW08_18155	COG5002	protein histidine kinase activity
DEW08_18160	COG0281	malic enzyme
DEW08_18160	COG0280	phosphate acetyltransferase
DEW08_18170	COG0606	chelatase, subunit chli
DEW08_18195	COG3191	aminopeptidase activity
DEW08_18200	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DEW08_18250	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DEW08_18265	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DEW08_18270	COG4166	transmembrane transport
DEW08_18290	COG1177	transmembrane transport
DEW08_18315	COG3842	ATPase activity
DEW08_18320	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DEW08_18355	COG1120	ATPase activity
DEW08_18365	COG1522	sequence-specific DNA binding
DEW08_18390	COG2010	Cytochrome c
DEW08_18395	COG3108	Peptidase M15
DEW08_18415	COG2271	Major facilitator Superfamily
DEW08_18420	COG1609	Transcriptional regulator
DEW08_18425	COG1475	DNA binding
DEW08_18430	COG1192	Involved in chromosome partitioning
DEW08_18435	COG3706	GGDEF domain
DEW08_18440	COG0596	Alpha beta hydrolase
DEW08_18450	COG1802	Transcriptional regulator
DEW08_18460	COG1960	acyl-CoA dehydrogenase activity
DEW08_18505	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DEW08_18510	COG0045	succinate-CoA ligase (ADP-forming) activity
DEW08_18515	COG4221	oxidoreductase activity
DEW08_18585	COG1215	transferase activity, transferring glycosyl groups
DEW08_18595	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DEW08_18630	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DEW08_18640	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DEW08_18665	COG1032	radical SAM domain protein
DEW08_18670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DEW08_18675	COG1088	dTDP-glucose 4,6-dehydratase activity
DEW08_18700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DEW08_18725	COG0156	8-amino-7-oxononanoate synthase activity
DEW08_18735	COG1448	Aminotransferase
DEW08_18750	COG5002	protein histidine kinase activity
DEW08_18755	COG0840	transmembrane signaling receptor activity
DEW08_18775	COG1752	Esterase of the alpha-beta hydrolase superfamily
DEW08_18805	COG3842	ATPase activity
DEW08_18830	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DEW08_18835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DEW08_18850	COG4191	Histidine kinase
DEW08_18855	COG4566	intracellular signal transduction
DEW08_18860	COG4566	intracellular signal transduction
DEW08_18865	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DEW08_18870	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DEW08_18875	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DEW08_18880	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DEW08_18890	COG0356	it plays a direct role in the translocation of protons across the membrane
DEW08_18910	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
DEW08_18915	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DEW08_18940	COG2197	response regulator
DEW08_18955	COG1462	curli production assembly transport component CsgG
DEW08_18975	COG2226	methyltransferase
DEW08_18990	COG1045	serine acetyltransferase
DEW08_19030	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DEW08_19030	COG1648	precorrin-2 dehydrogenase activity
DEW08_19040	COG3391	amine dehydrogenase activity
DEW08_19065	COG0535	radical SAM domain protein
DEW08_19075	COG0181	hydroxymethylbilane synthase activity
DEW08_19090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DEW08_19110	COG0683	leucine binding
DEW08_19115	COG1940	carbohydrate kinase activity
DEW08_19125	COG1172	Belongs to the binding-protein-dependent transport system permease family
DEW08_19130	COG1879	ABC-type sugar transport system periplasmic component
DEW08_19145	COG2115	Belongs to the xylose isomerase family
DEW08_19150	COG1070	Carbohydrate kinase
DEW08_19160	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DEW08_19180	COG5443	negative regulation of bacterial-type flagellum assembly
DEW08_19210	COG1157	protein secretion by the type III secretion system
DEW08_19215	COG1815	bacterial-type flagellum-dependent cell motility
DEW08_19220	COG1558	bacterial-type flagellum-dependent cell motility
DEW08_19225	COG1677	Flagellar hook-basal body complex protein FliE
DEW08_19230	COG4794	Type iii secretion
DEW08_19240	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DEW08_19245	COG1684	flagellar biosynthetic protein fliR
DEW08_19250	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DEW08_19285	COG1706	bacterial-type flagellum-dependent cell motility
DEW08_19300	COG1749	Flagellar hook protein flgE
DEW08_19310	COG1360	Flagellar Motor Protein
DEW08_19335	COG4786	Flagellar basal body rod
DEW08_19340	COG4786	Flagellar basal body rod
DEW08_19345	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
DEW08_19350	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
DEW08_19390	COG1766	The M ring may be actively involved in energy transduction
DEW08_19400	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DEW08_19405	COG1338	Plays a role in the flagellum-specific transport system
DEW08_19415	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DEW08_19425	COG0745	RESPONSE REGULATOR receiver
DEW08_19440	COG4251	negative regulation of phosphorylation
DEW08_19445	COG0784	Response regulator, receiver
DEW08_19450	COG3706	GGDEF domain
DEW08_19455	COG4251	negative regulation of phosphorylation
DEW08_19460	COG4251	negative regulation of phosphorylation
DEW08_19465	COG0784	Response regulator, receiver
DEW08_19485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DEW08_19490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DEW08_19505	COG2186	Transcriptional regulator
DEW08_19515	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DEW08_19520	COG1454	alcohol dehydrogenase
DEW08_19525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DEW08_19545	COG3971	2-oxopent-4-enoate hydratase activity
DEW08_19550	COG1028	Short-chain dehydrogenase reductase Sdr
DEW08_19565	COG4774	siderophore transport
DEW08_19570	COG2819	hydrolase of the alpha beta superfamily
DEW08_19585	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
DEW08_19595	COG1215	transferase activity, transferring glycosyl groups
DEW08_19600	COG0626	cystathionine gamma-synthase activity
DEW08_19660	COG1620	l-lactate permease
DEW08_19675	COG0183	Belongs to the thiolase family
DEW08_19680	COG1024	Enoyl-CoA hydratase
DEW08_19690	COG2814	Major facilitator Superfamily
DEW08_19695	COG1522	sequence-specific DNA binding
DEW08_19705	COG1192	Involved in chromosome partitioning
DEW08_19710	COG1475	DNA binding
DEW08_19750	COG3251	PFAM MbtH domain protein
DEW08_19770	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DEW08_19775	COG0367	asparagine synthase
DEW08_19780	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DEW08_19785	COG1250	3-hydroxyacyl-CoA dehydrogenase
DEW08_19795	COG1960	acyl-CoA dehydrogenase activity
DEW08_19805	COG1289	transmembrane transporter activity
DEW08_19815	COG1566	PFAM secretion protein HlyD family protein
DEW08_19830	COG5001	Diguanylate cyclase
DEW08_19830	COG3300	MHYT domain
DEW08_19835	COG0784	Response regulator, receiver
DEW08_19855	COG1136	(ABC) transporter
DEW08_19920	COG1032	radical SAM domain protein
DEW08_19945	COG1283	sodium-dependent phosphate transmembrane transporter activity
DEW08_19955	COG1446	asparaginase
DEW08_19970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEW08_19980	COG0747	negative chemotaxis
DEW08_19985	COG4172	Belongs to the ABC transporter superfamily
DEW08_20000	COG3938	Belongs to the proline racemase family
DEW08_20010	COG1802	Transcriptional regulator
DEW08_20020	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DEW08_20025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DEW08_20030	COG0683	leucine binding
DEW08_20055	COG0659	secondary active sulfate transmembrane transporter activity
DEW08_20060	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
DEW08_20065	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
DEW08_20070	COG0583	DNA-binding transcription factor activity
DEW08_20075	COG1802	Transcriptional regulator
DEW08_20090	COG1268	BioY protein
DEW08_20100	COG1122	ATPase activity
DEW08_20175	COG1063	alcohol dehydrogenase
DEW08_20180	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DEW08_20190	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DEW08_20195	COG2721	sulfolactate sulfo-lyase activity
DEW08_20200	COG0246	Mannitol dehydrogenase
DEW08_20215	COG1132	(ABC) transporter
DEW08_20220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEW08_20230	COG1120	ATPase activity
DEW08_20235	COG4774	siderophore transport
DEW08_20255	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DEW08_20265	COG1309	transcriptional regulator
DEW08_20285	COG1309	transcriptional regulator
DEW08_20300	COG4459	periplasmic nitrate reductase
DEW08_20310	COG0243	molybdopterin cofactor binding
DEW08_20320	COG3005	denitrification pathway
DEW08_20325	COG0410	ABC transporter
DEW08_20340	COG0559	Belongs to the binding-protein-dependent transport system permease family
DEW08_20355	COG0745	RESPONSE REGULATOR receiver
DEW08_20360	COG2201	protein-glutamate methylesterase activity
DEW08_20380	COG2186	Transcriptional regulator
DEW08_20385	COG2807	transmembrane transport
DEW08_20390	COG1414	Transcriptional regulator
DEW08_20405	COG2351	hydroxyisourate hydrolase activity
DEW08_20455	COG1802	Transcriptional regulator
DEW08_20475	COG5002	protein histidine kinase activity
DEW08_20475	COG5001	Diguanylate cyclase
DEW08_20495	COG2205	protein histidine kinase activity
DEW08_20500	COG0745	RESPONSE REGULATOR receiver
DEW08_20505	COG3842	ATPase activity
DEW08_20530	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DEW08_20535	COG0205	6-phosphofructokinase activity
DEW08_20555	COG2205	protein histidine kinase activity
DEW08_20555	COG0784	Response regulator, receiver
DEW08_20565	COG0753	catalase activity
DEW08_20570	COG0583	DNA-binding transcription factor activity
DEW08_20575	COG0667	Aldo Keto reductase
DEW08_20620	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
DEW08_20645	COG0438	transferase activity, transferring glycosyl groups
DEW08_20665	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DEW08_20670	COG1215	transferase activity, transferring glycosyl groups
DEW08_20675	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
DEW08_20680	COG0438	transferase activity, transferring glycosyl groups
DEW08_20705	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DEW08_20715	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DEW08_20720	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DEW08_20760	COG2856	Zn peptidase
DEW08_20770	COG1278	Cold shock
DEW08_20780	COG3795	YCII-related domain
DEW08_20805	COG1473	amidohydrolase
DEW08_20845	COG1462	curli production assembly transport component CsgG
DEW08_20865	COG4774	siderophore transport
DEW08_20910	COG0655	NAD(P)H dehydrogenase (quinone) activity
DEW08_20915	COG0583	DNA-binding transcription factor activity
DEW08_20980	COG4566	intracellular signal transduction
DEW08_20985	COG4191	Histidine kinase
DEW08_21000	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DEW08_21005	COG2111	Na H antiporter
DEW08_21005	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DEW08_21010	COG1006	Multisubunit Na H antiporter MnhC subunit
DEW08_21015	COG0651	ATP synthesis coupled electron transport
DEW08_21020	COG1863	multisubunit Na H antiporter MnhE subunit
DEW08_21025	COG2212	antiporter activity
DEW08_21030	COG1320	monovalent cation:proton antiporter activity
DEW08_21140	COG4962	Type ii secretion system protein e
DEW08_21155	COG3451	type IV secretory pathway VirB4
DEW08_21170	COG3846	protein secretion by the type IV secretion system
DEW08_21175	COG3701	Conjugal transfer protein
DEW08_21225	COG0840	transmembrane signaling receptor activity
DEW08_21250	COG2197	response regulator
DEW08_21260	COG3437	response regulator, receiver
DEW08_21260	COG3850	Histidine kinase
DEW08_21260	COG2205	protein histidine kinase activity
DEW08_21260	COG4999	Histidine kinase
DEW08_21270	COG2801	Transposase and inactivated derivatives
DEW08_21280	COG3279	Response regulator of the LytR AlgR family
DEW08_21290	COG2011	ABC-type metal ion transport system permease component
DEW08_21325	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DEW08_21335	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DEW08_21360	COG1530	ribonuclease E activity
DEW08_21365	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
DEW08_21395	COG1177	transmembrane transport
DEW08_21410	COG3842	ATPase activity
DEW08_21415	COG1609	Transcriptional regulator
DEW08_21425	COG2130	NADP-dependent
DEW08_21430	COG1979	alcohol dehydrogenase
DEW08_21435	COG1309	transcriptional regulator
DEW08_21450	COG0640	Transcriptional regulator
DEW08_21465	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DEW08_21495	COG0521	Mo-molybdopterin cofactor biosynthetic process
DEW08_21510	COG4263	nitrous-oxide reductase activity
DEW08_21525	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DEW08_21540	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DEW08_21560	COG0577	efflux transmembrane transporter activity
DEW08_21560	COG1136	(ABC) transporter
DEW08_21565	COG1136	(ABC) transporter
DEW08_21565	COG0577	efflux transmembrane transporter activity
DEW08_21575	COG0784	Response regulator, receiver
DEW08_21575	COG4191	Histidine kinase
DEW08_21580	COG0569	domain protein
DEW08_21585	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DEW08_21590	COG1858	cytochrome C peroxidase
DEW08_21620	COG1749	Flagellar hook protein flgE
DEW08_21620	COG1749	Flagellar hook protein flgE
DEW08_21635	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
DEW08_21660	COG5433	transposase activity
DEW08_21675	COG0435	Glutathione S-transferase
DEW08_21680	COG0583	DNA-binding transcription factor activity
DEW08_21690	COG0697	spore germination
DEW08_21705	COG0859	PFAM glycosyl transferase family 9
DEW08_21710	COG0795	lipopolysaccharide-transporting ATPase activity
DEW08_21735	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DEW08_21755	COG1294	oxidase, subunit
DEW08_21760	COG1271	oxidase subunit
DEW08_21765	COG2095	MarC family integral membrane protein
DEW08_21790	COG1268	BioY protein
DEW08_21800	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DEW08_21805	COG3800	Transcriptional regulator
DEW08_21805	COG1396	sequence-specific DNA binding
DEW08_21810	COG1309	transcriptional regulator
DEW08_21830	COG3106	COG3106 Predicted ATPase
DEW08_21835	COG3768	UPF0283 membrane protein
DEW08_21840	COG0071	Belongs to the small heat shock protein (HSP20) family
DEW08_21855	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DEW08_21870	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DEW08_21880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DEW08_21890	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DEW08_21895	COG1882	Formate acetyltransferase
DEW08_21900	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DEW08_21910	COG1686	Belongs to the peptidase S11 family
DEW08_21945	COG1132	(ABC) transporter
DEW08_21965	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DEW08_21980	COG4214	carbohydrate transport
DEW08_21990	COG0129	dihydroxy-acid dehydratase activity
DEW08_22020	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DEW08_22030	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DEW08_22050	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
DEW08_22055	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DEW08_22060	COG1028	Short-chain dehydrogenase reductase Sdr
DEW08_22065	COG1802	Transcriptional regulator
DEW08_22080	COG1363	Peptidase, m42
DEW08_22090	COG0367	asparagine synthase
DEW08_22100	COG2814	Major facilitator Superfamily
DEW08_22105	COG0583	DNA-binding transcription factor activity
DEW08_22195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DEW08_22205	COG3852	Histidine kinase
DEW08_22210	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DEW08_22250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DEW08_22255	COG0583	DNA-binding transcription factor activity
DEW08_22260	COG0174	glutamine synthetase
DEW08_22265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DEW08_22290	COG1749	Flagellar hook protein flgE
DEW08_22305	COG2814	Major facilitator Superfamily
DEW08_22325	COG2217	Heavy metal translocating P-type atpase
DEW08_22345	COG2860	membrane
DEW08_22360	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DEW08_22370	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DEW08_22380	COG0840	transmembrane signaling receptor activity
DEW08_22400	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DEW08_22400	COG3218	ABC-type transport auxiliary lipoprotein component
DEW08_22405	COG1127	ABC transporter
DEW08_22410	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DEW08_22415	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DEW08_22460	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DEW08_22465	COG0697	spore germination
DEW08_22470	COG2824	Alkylphosphonate utilization operon protein PhnA
DEW08_22490	COG2884	Cell division ATP-binding protein ftsE
DEW08_22565	COG0489	protein tyrosine kinase activity
DEW08_22565	COG3206	protein involved in exopolysaccharide biosynthesis
DEW08_22580	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DEW08_22585	COG1045	serine acetyltransferase
DEW08_22605	COG1215	transferase activity, transferring glycosyl groups
DEW08_22610	COG0438	transferase activity, transferring glycosyl groups
DEW08_22615	COG0438	transferase activity, transferring glycosyl groups
DEW08_22625	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DEW08_22630	COG0318	PFAM AMP-dependent synthetase and ligase
DEW08_22635	COG0367	asparagine synthase
DEW08_22640	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DEW08_22665	COG0745	RESPONSE REGULATOR receiver
DEW08_22675	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DEW08_22680	COG4208	sulfate ABC transporter
DEW08_22690	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DEW08_22700	COG1959	2 iron, 2 sulfur cluster binding
DEW08_22705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DEW08_22710	COG1475	DNA binding
DEW08_22715	COG1192	Involved in chromosome partitioning
DEW08_22725	COG3842	ATPase activity
DEW08_22730	COG2182	Extracellular solute-binding protein
DEW08_22735	COG1176	ABC-type spermidine putrescine transport system, permease component I
DEW08_22750	COG1917	Cupin 2, conserved barrel domain protein
DEW08_22750	COG1396	sequence-specific DNA binding
DEW08_22755	COG1012	belongs to the aldehyde dehydrogenase family
DEW08_22790	COG3273	potassium ion transport
DEW08_22790	COG0471	metal ion transport
DEW08_22810	COG2205	protein histidine kinase activity
DEW08_22810	COG2202	Pas domain
DEW08_22830	COG1250	3-hydroxyacyl-CoA dehydrogenase
DEW08_22830	COG1024	Enoyl-CoA hydratase
DEW08_22850	COG3047	cAMP biosynthetic process
DEW08_22895	COG0625	glutathione transferase activity
DEW08_22900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DEW08_22925	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DEW08_22925	COG2813	Specifically methylates the guanine in position
DEW08_22930	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DEW08_22935	COG0077	Prephenate dehydratase
DEW08_22935	COG1605	Chorismate mutase
DEW08_22940	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DEW08_22955	COG0455	bacterial-type flagellum organization
DEW08_22965	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DEW08_22970	COG2204	response regulator
DEW08_22975	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DEW08_22980	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DEW08_22995	COG1396	sequence-specific DNA binding
DEW08_23000	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
DEW08_23025	COG2205	protein histidine kinase activity
DEW08_23035	COG1253	flavin adenine dinucleotide binding
DEW08_23045	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DEW08_23070	COG0559	Belongs to the binding-protein-dependent transport system permease family
DEW08_23085	COG0772	Belongs to the SEDS family
DEW08_23095	COG2189	Belongs to the N(4) N(6)-methyltransferase family
DEW08_23105	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DEW08_23110	COG3012	SEC-C Motif Domain Protein
DEW08_23115	COG1278	Cold shock
DEW08_23160	COG0521	Mo-molybdopterin cofactor biosynthetic process
DEW08_23165	COG0741	lytic transglycosylase activity
DEW08_23170	COG1573	uracil-dna glycosylase
DEW08_23185	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
DEW08_23190	COG2027	D-alanyl-D-alanine carboxypeptidase
DEW08_23205	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DEW08_23210	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DEW08_23215	COG0671	phosphoesterase, PA-phosphatase related
DEW08_23250	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DEW08_23285	COG0793	Belongs to the peptidase S41A family
DEW08_23295	COG0861	Integral membrane protein TerC family
DEW08_23315	COG0019	diaminopimelate decarboxylase activity
DEW08_23325	COG0165	Argininosuccinate lyase
DEW08_23330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DEW08_23335	COG1250	3-hydroxyacyl-CoA dehydrogenase
DEW08_23360	COG2723	6-phospho-beta-galactosidase activity
DEW08_23365	COG2249	NAD(P)H dehydrogenase (quinone) activity
DEW08_23385	COG1196	nuclear chromosome segregation
DEW08_23390	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DEW08_23410	COG4191	Histidine kinase
DEW08_23420	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
DEW08_23425	COG0840	transmembrane signaling receptor activity
DEW08_23440	COG1294	oxidase, subunit
DEW08_23445	COG1271	oxidase subunit
DEW08_23460	COG0531	amino acid
DEW08_23465	COG4302	ethanolamine ammonia-lyase activity
DEW08_23470	COG4303	Ethanolamine ammonia lyase large subunit
DEW08_23475	COG0740	serine-type endopeptidase activity
DEW08_23480	COG1215	transferase activity, transferring glycosyl groups
DEW08_23490	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DEW08_23505	COG0508	dehydrogenase complex catalyzes the overall conversion of
DEW08_23505	COG0596	Alpha beta hydrolase
DEW08_23515	COG4953	penicillin-binding protein 1C
DEW08_23530	COG2132	Multicopper oxidase
DEW08_23540	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DEW08_23550	COG1840	ABC-type Fe3 transport system, periplasmic component
DEW08_23560	COG0667	Aldo Keto reductase
DEW08_23595	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DEW08_23595	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DEW08_23600	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DEW08_23610	COG2205	protein histidine kinase activity
DEW08_23620	COG1733	regulation of RNA biosynthetic process
DEW08_23640	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DEW08_23640	COG0519	Catalyzes the synthesis of GMP from XMP
DEW08_23660	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DEW08_23675	COG1758	RNA polymerase activity
DEW08_23685	COG0537	adenosine 5'-monophosphoramidase activity
DEW08_23690	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DEW08_23695	COG0736	holo-[acyl-carrier-protein] synthase activity
DEW08_23700	COG0681	Belongs to the peptidase S26 family
DEW08_23705	COG0571	ribonuclease III activity
DEW08_23710	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DEW08_23715	COG0140	phosphoribosyl-ATP diphosphatase activity
DEW08_23720	COG0704	Plays a role in the regulation of phosphate uptake
DEW08_23735	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
DEW08_23740	COG0768	penicillin binding
DEW08_23745	COG0500	methyltransferase
DEW08_23765	COG1116	anion transmembrane transporter activity
DEW08_23785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DEW08_23790	COG0840	transmembrane signaling receptor activity
DEW08_23800	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DEW08_23805	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DEW08_23810	COG0351	phosphomethylpyrimidine kinase
DEW08_23815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DEW08_23820	COG0300	oxidoreductase activity
DEW08_23850	COG2030	dehydratase
DEW08_23870	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DEW08_23875	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DEW08_23890	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DEW08_23915	COG0546	phosphoglycolate phosphatase activity
DEW08_23930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DEW08_23930	COG4191	Histidine kinase
DEW08_23940	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DEW08_23960	COG1940	carbohydrate kinase activity
DEW08_24015	COG3344	reverse transcriptase
DEW08_24035	COG2885	chlorophyll binding
DEW08_24035	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DEW08_24055	COG0564	pseudouridine synthase activity
DEW08_24060	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DEW08_24060	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DEW08_24100	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DEW08_24130	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
DEW08_24165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DEW08_24170	COG1116	anion transmembrane transporter activity
DEW08_24175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DEW08_24180	COG0583	DNA-binding transcription factor activity
DEW08_24200	COG1116	anion transmembrane transporter activity
DEW08_24205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DEW08_24210	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
DEW08_24230	COG0559	Belongs to the binding-protein-dependent transport system permease family
DEW08_24245	COG2072	flavoprotein involved in K transport
DEW08_24255	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DEW08_24255	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DEW08_24270	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DEW08_24275	COG2226	methyltransferase
DEW08_24280	COG0583	DNA-binding transcription factor activity
DEW08_24290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DEW08_24295	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DEW08_24300	COG4191	Histidine kinase
DEW08_24305	COG4566	intracellular signal transduction
DEW08_24335	COG2205	protein histidine kinase activity
DEW08_24355	COG1136	(ABC) transporter
DEW08_24375	COG1064	alcohol dehydrogenase
DEW08_24380	COG1172	Belongs to the binding-protein-dependent transport system permease family
DEW08_24385	COG1172	Belongs to the binding-protein-dependent transport system permease family
DEW08_24405	COG1879	ABC-type sugar transport system periplasmic component
DEW08_24410	COG1129	ABC transporter
DEW08_24415	COG1172	Belongs to the binding-protein-dependent transport system permease family
DEW08_24475	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DEW08_24480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEW08_24490	COG2706	6-phosphogluconolactonase activity
DEW08_24495	COG0656	L-ascorbic acid biosynthetic process
DEW08_24535	COG1522	sequence-specific DNA binding
DEW08_24540	COG0488	(ABC) transporter
DEW08_24550	COG0840	transmembrane signaling receptor activity
DEW08_24560	COG2197	response regulator
DEW08_24565	COG2197	response regulator
DEW08_24575	COG3260	NADH ubiquinone oxidoreductase 20
DEW08_24580	COG0649	NAD binding
DEW08_24585	COG0651	ATP synthesis coupled electron transport
DEW08_24595	COG0650	Formate hydrogenlyase subunit 4
DEW08_24600	COG0651	ATP synthesis coupled electron transport
DEW08_24605	COG2183	response to ionizing radiation
DEW08_24620	COG1280	lysine exporter protein (LysE YggA)
DEW08_24650	COG0393	Putative heavy-metal-binding
DEW08_24655	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DEW08_24675	COG0297	glycogen (starch) synthase activity
DEW08_24715	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DEW08_24720	COG0784	Response regulator, receiver
DEW08_24725	COG0625	glutathione transferase activity
DEW08_24730	COG5002	protein histidine kinase activity
DEW08_24770	COG0719	Fe-S assembly protein
DEW08_24775	COG0396	ATPase activity
DEW08_24780	COG0719	Fe-S assembly protein
DEW08_24785	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DEW08_24790	COG0822	iron-sulfur transferase activity
DEW08_24795	COG2151	metal-sulfur cluster biosynthetic enzyme
DEW08_24800	COG0316	Belongs to the HesB IscA family
DEW08_24805	COG0840	transmembrane signaling receptor activity
DEW08_24815	COG0308	aminopeptidase N
DEW08_24835	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DEW08_24870	COG0287	Prephenate dehydrogenase
DEW08_24880	COG1157	protein secretion by the type III secretion system
DEW08_24885	COG0745	RESPONSE REGULATOR receiver
DEW08_24890	COG1278	Cold shock
DEW08_24915	COG2201	protein-glutamate methylesterase activity
DEW08_24920	COG0835	chemotaxis
DEW08_24925	COG2198	Histidine kinase
DEW08_24925	COG0643	Histidine kinase
DEW08_24945	COG2205	protein histidine kinase activity
DEW08_24955	COG3920	Histidine kinase
DEW08_24965	COG3416	Protein conserved in bacteria
DEW08_24980	COG3920	Histidine kinase
DEW08_24995	COG0643	Histidine kinase
DEW08_24995	COG2198	Histidine kinase
DEW08_25005	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DEW08_25015	COG2201	protein-glutamate methylesterase activity
DEW08_25025	COG0840	transmembrane signaling receptor activity
DEW08_25065	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
DEW08_25100	COG2132	Multicopper oxidase
DEW08_25115	COG0477	Major facilitator Superfamily
DEW08_25120	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DEW08_25125	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DEW08_25130	COG1845	cytochrome c oxidase, subunit III
DEW08_25135	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DEW08_25150	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
DEW08_25155	COG1960	acyl-CoA dehydrogenase activity
DEW08_25160	COG0840	transmembrane signaling receptor activity
DEW08_25170	COG0840	transmembrane signaling receptor activity
DEW08_25175	COG3275	phosphorelay sensor kinase activity
DEW08_25180	COG3279	Response regulator of the LytR AlgR family
DEW08_25200	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DEW08_25225	COG1131	(ABC) transporter
DEW08_25255	COG2010	Cytochrome c
DEW08_25270	COG1966	Carbon starvation protein
DEW08_25275	COG1882	Formate acetyltransferase
DEW08_25285	COG1126	abc transporter atp-binding protein
DEW08_25290	COG0765	amino acid transport
DEW08_25295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DEW08_25300	COG5002	protein histidine kinase activity
DEW08_25300	COG5001	Diguanylate cyclase
DEW08_25305	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DEW08_25320	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DEW08_25325	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DEW08_25340	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
DEW08_25345	COG1028	Short-chain dehydrogenase reductase Sdr
DEW08_25350	COG1917	Cupin 2, conserved barrel domain protein
DEW08_25355	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
DEW08_25390	COG0800	Aldolase
DEW08_25405	COG1028	Short-chain dehydrogenase reductase Sdr
DEW08_25410	COG0375	protein maturation
DEW08_25415	COG0437	4 iron, 4 sulfur cluster binding
DEW08_25420	COG2414	aldehyde ferredoxin oxidoreductase
DEW08_25435	COG0651	ATP synthesis coupled electron transport
DEW08_25445	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DEW08_25455	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEW08_25460	COG0649	NAD binding
DEW08_25475	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DEW08_25485	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DEW08_25490	COG1802	Transcriptional regulator
DEW08_25495	COG0435	Glutathione S-transferase
DEW08_25500	COG2353	YceI-like domain
DEW08_25515	COG1312	Catalyzes the dehydration of D-mannonate
DEW08_25520	COG0246	Mannitol dehydrogenase
DEW08_25525	COG3622	Belongs to the hyi family
DEW08_25530	COG2223	nitrite transmembrane transporter activity
DEW08_25535	COG0515	serine threonine protein kinase
DEW08_25535	COG2815	serine threonine protein kinase
DEW08_25540	COG2116	formate transmembrane transporter activity
DEW08_25545	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DEW08_25550	COG2986	histidine ammonia-lyase
DEW08_25555	COG1228	amidohydrolase
DEW08_25585	COG2188	Transcriptional regulator
DEW08_25610	COG1172	Belongs to the binding-protein-dependent transport system permease family
DEW08_25615	COG1129	ABC transporter
DEW08_25620	COG1879	ABC-type sugar transport system periplasmic component
DEW08_25625	COG1984	allophanate hydrolase subunit 2
DEW08_25640	COG0511	ligase activity, forming carbon-carbon bonds
DEW08_25660	COG3005	denitrification pathway
DEW08_25670	COG0583	DNA-binding transcription factor activity
DEW08_25675	COG2851	Citrate transporter
DEW08_25690	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DEW08_25695	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DEW08_25710	COG0459	protein refolding
DEW08_25725	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DEW08_25740	COG0346	lactoylglutathione lyase activity
DEW08_25760	COG3609	addiction module antidote protein, CC2985 family
DEW08_25765	COG2116	formate transmembrane transporter activity
DEW08_25785	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
DEW08_25785	COG2273	Hydrolase Family 16
DEW08_25790	COG3284	Transcriptional regulator
DEW08_25795	COG3199	ATP-NAD kinase
DEW08_25800	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DEW08_25805	COG0022	dehydrogenase e1 component
DEW08_25810	COG0508	dehydrogenase complex catalyzes the overall conversion of
DEW08_25810	COG0596	Alpha beta hydrolase
DEW08_25825	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DEW08_25835	COG1879	ABC-type sugar transport system periplasmic component
DEW08_25840	COG1129	ABC transporter
DEW08_25845	COG1172	Belongs to the binding-protein-dependent transport system permease family
DEW08_25850	COG1172	Belongs to the binding-protein-dependent transport system permease family
DEW08_25860	COG0840	transmembrane signaling receptor activity
DEW08_25865	COG0280	phosphate acetyltransferase
DEW08_25870	COG1760	l-serine dehydratase
DEW08_25875	COG0814	amino acid
DEW08_25880	COG3275	phosphorelay sensor kinase activity
DEW08_25885	COG3279	Response regulator of the LytR AlgR family
DEW08_25930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DEW08_25940	COG0300	oxidoreductase activity
DEW08_25950	COG0640	Transcriptional regulator
DEW08_25980	COG0745	RESPONSE REGULATOR receiver
DEW08_25995	COG1028	Short-chain dehydrogenase reductase Sdr
DEW08_26020	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DEW08_26035	COG3920	Histidine kinase
DEW08_26045	COG0318	PFAM AMP-dependent synthetase and ligase
DEW08_26050	COG1309	transcriptional regulator
DEW08_26055	COG1250	3-hydroxyacyl-CoA dehydrogenase
DEW08_26070	COG1263	PTS System
DEW08_26070	COG2190	(PTS) system
DEW08_26070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DEW08_26075	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DEW08_26115	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DEW08_26120	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DEW08_26125	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
DEW08_26125	COG0493	'glutamate synthase
DEW08_26140	COG1309	transcriptional regulator
DEW08_26155	COG0784	Response regulator, receiver
DEW08_26155	COG4191	Histidine kinase
DEW08_26165	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DEW08_26170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DEW08_26180	COG1172	Belongs to the binding-protein-dependent transport system permease family
DEW08_26185	COG1172	Belongs to the binding-protein-dependent transport system permease family
DEW08_26190	COG1129	ABC transporter
DEW08_26195	COG1879	ABC-type sugar transport system periplasmic component
DEW08_26200	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DEW08_26205	COG1349	DNA-binding transcription factor activity
DEW08_26220	COG0747	negative chemotaxis
DEW08_26225	COG0601	transmembrane transport
DEW08_26230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEW08_26245	COG0438	transferase activity, transferring glycosyl groups
DEW08_26250	COG0588	phosphoglycerate mutase activity
DEW08_26275	COG5433	transposase activity
DEW08_26280	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
DEW08_26295	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DEW08_26315	COG0840	transmembrane signaling receptor activity
DEW08_26320	COG1309	transcriptional regulator
DEW08_26325	COG1028	Short-chain dehydrogenase reductase Sdr
DEW08_26350	COG0348	domain, Protein
DEW08_26355	COG0437	4 iron, 4 sulfur cluster binding
DEW08_26385	COG0714	Associated with various cellular activities
DEW08_26445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DEW08_26450	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DEW08_26465	COG2902	Dehydrogenase
DEW08_26470	COG0583	DNA-binding transcription factor activity
DEW08_26515	COG5001	Diguanylate cyclase
DEW08_26515	COG3300	MHYT domain
DEW08_26525	COG0366	Alpha amylase catalytic
DEW08_26530	COG1028	Short-chain dehydrogenase reductase Sdr
DEW08_26565	COG1028	Short-chain dehydrogenase reductase Sdr
DEW08_26575	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DEW08_26580	COG3162	membrane
DEW08_26595	COG0318	PFAM AMP-dependent synthetase and ligase
DEW08_26610	COG1960	acyl-CoA dehydrogenase activity
DEW08_26615	COG1802	Transcriptional regulator
DEW08_26620	COG1803	Methylglyoxal synthase
DEW08_26625	COG1904	glucuronate isomerase
DEW08_26630	COG2721	sulfolactate sulfo-lyase activity
DEW08_26635	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DEW08_26645	COG3493	citrate carrier protein
DEW08_26655	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
DEW08_26675	COG3052	prosthetic group binding
DEW08_26680	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
DEW08_26685	COG0179	Fumarylacetoacetate (FAA) hydrolase
DEW08_26690	COG0280	phosphate acetyltransferase
DEW08_26690	COG0281	malic enzyme
DEW08_26705	COG3180	Ammonia monooxygenase
DEW08_26715	COG4604	ABC transporter, ATP-binding protein
DEW08_26720	COG4605	iron ion homeostasis
DEW08_26725	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DEW08_26730	COG4607	ABC-type enterochelin transport system periplasmic component
DEW08_26735	COG1695	Transcriptional regulator
DEW08_26745	COG2186	Transcriptional regulator
DEW08_26750	COG1312	Catalyzes the dehydration of D-mannonate
DEW08_26755	COG1028	Short-chain dehydrogenase reductase Sdr
DEW08_26765	COG2186	Transcriptional regulator
DEW08_26770	COG3842	ATPase activity
DEW08_26780	COG1176	ABC-type spermidine putrescine transport system, permease component I
DEW08_26785	COG0581	inorganic phosphate transmembrane transporter activity
DEW08_26800	COG1760	l-serine dehydratase
DEW08_26810	COG3344	reverse transcriptase
DEW08_26820	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DEW08_26820	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DEW08_26825	COG1105	Belongs to the carbohydrate kinase PfkB family
DEW08_26830	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DEW08_26830	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DEW08_26835	COG1609	Transcriptional regulator
DEW08_26850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DEW08_26850	COG1263	PTS System
DEW08_26860	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DEW08_26860	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DEW08_26865	COG1124	(ABC) transporter
DEW08_26870	COG0444	Belongs to the ABC transporter superfamily
DEW08_26875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEW08_26880	COG0601	transmembrane transport
DEW08_26885	COG0747	negative chemotaxis
DEW08_26895	COG2273	Hydrolase Family 16
DEW08_26895	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
DEW08_26930	COG4106	trans-aconitate 2-methyltransferase activity
DEW08_26955	COG3005	denitrification pathway
DEW08_26995	COG0411	ABC transporter
DEW08_27010	COG2814	Major facilitator Superfamily
DEW08_27025	COG1024	Enoyl-CoA hydratase
DEW08_27065	COG4172	Belongs to the ABC transporter superfamily
DEW08_27070	COG0747	negative chemotaxis
DEW08_27085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEW08_27105	COG1966	Carbon starvation protein
DEW08_27120	COG2610	gluconate transmembrane transporter activity
DEW08_27125	COG3265	gluconokinase activity
DEW08_27130	COG0288	reversible hydration of carbon dioxide
DEW08_27135	COG1737	Transcriptional regulator
DEW08_27135	COG0837	glucose binding
DEW08_27155	COG1882	Formate acetyltransferase
DEW08_27160	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DEW08_27165	COG2116	formate transmembrane transporter activity
DEW08_27175	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DEW08_27180	COG0697	spore germination
DEW08_27195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DEW08_27200	COG1802	Transcriptional regulator
DEW08_27205	COG0800	Aldolase
DEW08_27215	COG0784	Response regulator, receiver
DEW08_27240	COG1116	anion transmembrane transporter activity
DEW08_27245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DEW08_27255	COG2205	protein histidine kinase activity
DEW08_27255	COG2202	Pas domain
DEW08_27270	COG1012	belongs to the aldehyde dehydrogenase family
DEW08_27275	COG0535	radical SAM domain protein
DEW08_27280	COG0535	radical SAM domain protein
DEW08_27285	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
DEW08_27290	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DEW08_27345	COG1131	(ABC) transporter
DEW08_27355	COG0840	transmembrane signaling receptor activity
DEW08_27360	COG0612	Peptidase, M16
DEW08_27365	COG2205	protein histidine kinase activity
DEW08_27365	COG0745	RESPONSE REGULATOR receiver
DEW08_27365	COG4191	Histidine kinase
DEW08_27425	COG0375	protein maturation
DEW08_27435	COG2204	response regulator
DEW08_27485	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
DEW08_27490	COG0583	DNA-binding transcription factor activity
DEW08_27495	COG0450	alkyl hydroperoxide reductase
DEW08_27500	COG3634	alkyl hydroperoxide reductase activity
DEW08_27505	COG3920	Histidine kinase
DEW08_27550	COG1349	DNA-binding transcription factor activity
DEW08_27560	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DEW08_27565	COG1609	Transcriptional regulator
DEW08_27570	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DEW08_27575	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DEW08_27585	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DEW08_27605	COG0798	PFAM Bile acid sodium symporter
DEW08_27625	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
DEW08_27630	COG3718	enzyme involved in inositol metabolism
DEW08_27635	COG1737	Transcriptional regulator
DEW08_27640	COG0673	inositol 2-dehydrogenase activity
DEW08_27650	COG1172	Belongs to the binding-protein-dependent transport system permease family
DEW08_27655	COG1129	ABC transporter
DEW08_27660	COG1879	ABC-type sugar transport system periplasmic component
DEW08_27675	COG3962	Belongs to the TPP enzyme family
DEW08_27680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DEW08_27685	COG3383	formate dehydrogenase (NAD+) activity
DEW08_27695	COG0667	Aldo Keto reductase
DEW08_27705	COG1432	Conserved Protein
DEW08_27715	COG1309	transcriptional regulator
DEW08_27725	COG4176	ABC-type proline glycine betaine transport system permease component
DEW08_27730	COG4175	Glycine betaine
DEW08_27735	COG1280	lysine exporter protein (LysE YggA)
DEW08_27740	COG1115	amino acid carrier protein
DEW08_27750	COG1942	4-Oxalocrotonate Tautomerase
DEW08_27765	COG1609	Transcriptional regulator
DEW08_27770	COG0246	Mannitol dehydrogenase
DEW08_27775	COG2271	Major facilitator Superfamily
DEW08_27815	COG0840	transmembrane signaling receptor activity
DEW08_27820	COG1846	Transcriptional regulator
DEW08_27835	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DEW08_27840	COG1250	3-hydroxyacyl-CoA dehydrogenase
DEW08_27895	COG5433	transposase activity
DEW08_27920	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DEW08_27920	COG2755	lipolytic protein G-D-S-L family
DEW08_27935	COG1475	DNA binding
DEW08_27960	COG5265	(ABC) transporter
DEW08_27970	COG0306	phosphate transporter
DEW08_28010	COG0436	Aminotransferase
DEW08_28145	COG0477	Major facilitator Superfamily
DEW08_28150	COG0784	Response regulator, receiver
DEW08_28150	COG2198	Histidine kinase
DEW08_28150	COG2205	protein histidine kinase activity
DEW08_28165	COG2205	protein histidine kinase activity
DEW08_28165	COG2202	Pas domain
DEW08_28180	COG0446	pyridine nucleotide-disulphide oxidoreductase
DEW08_28180	COG1902	pentaerythritol trinitrate reductase activity
DEW08_28190	COG2233	PERMEase
DEW08_28200	COG0704	Plays a role in the regulation of phosphate uptake
DEW08_28225	COG0745	RESPONSE REGULATOR receiver
DEW08_28245	COG3485	protocatechuate 3,4-dioxygenase
DEW08_28250	COG3485	protocatechuate 3,4-dioxygenase
DEW08_28260	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DEW08_28265	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DEW08_28275	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DEW08_28280	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DEW08_28285	COG0683	leucine binding
DEW08_28340	COG1869	D-ribose catabolic process
DEW08_28350	COG1172	Belongs to the binding-protein-dependent transport system permease family
DEW08_28355	COG1879	ABC-type sugar transport system periplasmic component
DEW08_28360	COG1609	Transcriptional regulator
DEW08_28370	COG0076	glutamate decarboxylase activity
DEW08_28375	COG1522	sequence-specific DNA binding
DEW08_28385	COG3005	denitrification pathway
DEW08_28395	COG0243	molybdopterin cofactor binding
DEW08_28410	COG4459	periplasmic nitrate reductase
DEW08_28425	COG1028	Short-chain dehydrogenase reductase Sdr
DEW08_28440	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DEW08_28445	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DEW08_28450	COG1028	Short-chain dehydrogenase reductase Sdr
DEW08_28455	COG2233	PERMEase
DEW08_28460	COG1971	Probably functions as a manganese efflux pump
DEW08_28465	COG0402	S-adenosylhomocysteine deaminase activity
DEW08_28490	COG1640	4-alpha-glucanotransferase
DEW08_28505	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DEW08_28510	COG0366	Alpha amylase catalytic
DEW08_28515	COG2233	PERMEase
DEW08_28525	COG3806	Anti-sigma factor
DEW08_28530	COG1595	DNA-templated transcription, initiation
DEW08_28535	COG0028	Belongs to the TPP enzyme family
DEW08_28560	COG2211	Major facilitator Superfamily
DEW08_28590	COG0028	Belongs to the TPP enzyme family
DEW08_28595	COG1122	ATPase activity
DEW08_28605	COG1268	BioY protein
DEW08_28610	COG0318	PFAM AMP-dependent synthetase and ligase
DEW08_28615	COG0183	Belongs to the thiolase family
DEW08_28660	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DEW08_28665	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
DEW08_28670	COG0412	Dienelactone hydrolase
DEW08_28725	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DEW08_28735	COG0295	cytidine deaminase activity
DEW08_28760	COG2378	regulation of single-species biofilm formation
DEW08_28810	COG1160	GTP binding
DEW08_28845	COG0354	folic acid binding
DEW08_28860	COG0546	phosphoglycolate phosphatase activity
DEW08_28865	COG0564	pseudouridine synthase activity
DEW08_28870	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DEW08_28875	COG1335	isochorismatase
DEW08_28885	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DEW08_28900	COG1238	metal cluster binding
DEW08_28905	COG0203	ribosomal protein L17
DEW08_28920	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DEW08_28925	COG5433	transposase activity
DEW08_28930	COG0469	pyruvate kinase activity
DEW08_28945	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DEW08_28950	COG0251	oxidation-reduction process
DEW08_28960	COG0551	DNA topoisomerase type I activity
DEW08_28960	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DEW08_28975	COG1960	acyl-CoA dehydrogenase activity
DEW08_29000	COG1595	DNA-templated transcription, initiation
DEW08_29040	COG0366	Alpha amylase catalytic
DEW08_29050	COG0840	transmembrane signaling receptor activity
DEW08_29055	COG0840	transmembrane signaling receptor activity
DEW08_29065	COG1487	ribonuclease activity
DEW08_29085	COG2814	Major facilitator Superfamily
DEW08_29090	COG4106	trans-aconitate 2-methyltransferase activity
DEW08_29105	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DEW08_29105	COG2169	Transcriptional regulator
DEW08_29125	COG0683	leucine binding
DEW08_29145	COG0601	transmembrane transport
DEW08_29155	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
DEW08_29170	COG0444	Belongs to the ABC transporter superfamily
DEW08_29185	COG1280	lysine exporter protein (LysE YggA)
DEW08_29200	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DEW08_29220	COG0840	transmembrane signaling receptor activity
DEW08_29245	COG3214	Protein conserved in bacteria
DEW08_29260	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DEW08_29260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DEW08_29275	COG4178	(ABC) transporter
DEW08_29295	COG0840	transmembrane signaling receptor activity
DEW08_29330	COG0686	Belongs to the AlaDH PNT family
DEW08_29335	COG1522	sequence-specific DNA binding
DEW08_29350	COG2199	diguanylate cyclase activity
DEW08_29350	COG2200	EAL domain
DEW08_29350	COG2203	Gaf domain
DEW08_29365	COG1218	3'(2'),5'-bisphosphate nucleotidase
DEW08_29370	COG2833	Protein of unknown function (DUF455)
DEW08_29375	COG1846	Transcriptional regulator
DEW08_29405	COG0251	oxidation-reduction process
DEW08_29415	COG1960	acyl-CoA dehydrogenase activity
DEW08_29420	COG1024	Enoyl-CoA hydratase
DEW08_29425	COG1028	Short-chain dehydrogenase reductase Sdr
DEW08_29475	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DEW08_29480	COG3550	peptidyl-serine autophosphorylation
DEW08_29485	COG0556	nucleotide-excision repair
DEW08_29505	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DEW08_29510	COG1028	Short-chain dehydrogenase reductase Sdr
DEW08_29520	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
DEW08_29535	COG0410	ABC transporter
DEW08_29605	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DEW08_29620	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DEW08_29640	COG1091	dTDP-4-dehydrorhamnose reductase activity
DEW08_29645	COG1088	dTDP-glucose 4,6-dehydratase activity
DEW08_29650	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
DEW08_29660	COG0500	methyltransferase
DEW08_29670	COG0438	transferase activity, transferring glycosyl groups
DEW08_29680	COG0463	Glycosyl transferase, family 2
DEW08_29695	COG0297	glycogen (starch) synthase activity
DEW08_29715	COG0463	Glycosyl transferase, family 2
DEW08_29735	COG0500	methyltransferase
DEW08_29750	COG1086	Polysaccharide biosynthesis protein
DEW08_29780	COG0500	methyltransferase
DEW08_29785	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DEW08_29790	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DEW08_29800	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DEW08_29800	COG0546	phosphoglycolate phosphatase activity
DEW08_29820	COG0300	oxidoreductase activity
DEW08_29830	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
DEW08_29845	COG0508	dehydrogenase complex catalyzes the overall conversion of
DEW08_29845	COG0022	dehydrogenase e1 component
DEW08_29850	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DEW08_29855	COG0784	Response regulator, receiver
DEW08_29855	COG2205	protein histidine kinase activity
DEW08_29860	COG0494	nUDIX hydrolase
DEW08_29915	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DEW08_29930	COG1083	cytidylyl-transferase
DEW08_29935	COG1032	radical SAM domain protein
DEW08_29960	COG1028	Short-chain dehydrogenase reductase Sdr
DEW08_29965	COG1028	Short-chain dehydrogenase reductase Sdr
DEW08_29995	COG2089	acid synthase
DEW08_30000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DEW08_30005	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DEW08_30010	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DEW08_30020	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DEW08_30030	COG1083	cytidylyl-transferase
DEW08_30035	COG1028	Short-chain dehydrogenase reductase Sdr
DEW08_30050	COG2089	acid synthase
DEW08_30055	COG0107	imidazoleglycerol-phosphate synthase activity
DEW08_30060	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DEW08_30075	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DEW08_30085	COG0297	glycogen (starch) synthase activity
DEW08_30110	COG1192	Involved in chromosome partitioning
DEW08_30115	COG1475	DNA binding
DEW08_30155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DEW08_30160	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DEW08_30205	COG1215	transferase activity, transferring glycosyl groups
DEW08_30215	COG0297	glycogen (starch) synthase activity
DEW08_30225	COG1216	Glycosyl transferase, family 2
DEW08_30230	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
DEW08_30395	COG1475	DNA binding